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Pulmonary hypertension is high blood pressure within the artery that connects the lungs and heart. It forces the heart to work harder to transfer blood between the heart and lungs, which may lead to an enlargement of the right side. Thyroid problems, whether they involve an underactive or overactive thyroid, can cause a heart to enlarge.
The right side of the heart (RA and RV) is responsible for pumping blood to the lungs, where the blood cells pick up fresh oxygen. This oxygenated blood is then returned to the left side of the heart (LA and LV).