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Mild Flu Shot Reactions. Mild Flu shot reactions include soreness, redness or swelling where the shot was given, hoarseness; sore, red or itchy eyes; cough, fever, and aches. A reaction to Flu vaccine continue they usually begin soon after the shot and last 1-2 days. Severe Flu Shot Reactions. Severe Flu shot reactions include allergic reactions. CDC says however that a life-threatening reaction to Flu vaccine is very rare. If Flu shot reactions occur, it is usually within a few minutes to a few hours after the vaccine.
Vaccines, like any medicine, can have side effects. For most vaccines, serious side effects are extremely rare. The risks of vaccines are much lower than the risks of the diseases they prevent. Different vaccines have different side effects, most of which are mild. They include: 1  temporary pain.2  redness, swelling, or soreness where the shot was given.3  short-lived flu-like symptoms.he risks of vaccines are much lower than the risks of the diseases they prevent. Different vaccines have different side effects, most of which are mild. They include: 1  temporary pain. 2  redness, swelling, or soreness where the shot was given. 3  short-lived flu-like symptoms.