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Answer Wiki. Some knots can come out within a couple minutes. Others never come out. I've had extreme back and neck pain for the past year and a half, most of it just tension in my muscles. I've had numerous massages, taken other treatment, all to no avail.
Muscle knots present as stiffening of shoulder or upper back muscles that makes any activity difficult across the inflamed muscles due to intense pain (and sometimes swelling). The size of muscle knots may vary from the size of a resin to about the size of thumb depending upon the number of muscle fibers involved.