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Bactrim is a sulfa-based antibiotic and is not a penicillin-based medicine, according to RxList. However, a patient should discuss all allergies with a doctor to determine what drugs can and cannot be taken. Continue Reading.
In particular, Bactrim is approved to treat the following infections: 1  Urinary tract infections (UTIs), such as bladder infections. 2  Ear infections. 3  Acute worsening of chronic bronchitis.  Shigellosis (a form of 1  dysentery) Traveler's diarrhea.  A certain type of pneumonia known as Pneumocystis carinii pneumonia.