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Mild Flu Shot Reactions. Mild Flu shot reactions include soreness, redness or swelling where the shot was given, hoarseness; sore, red or itchy eyes; cough, fever, and aches. A reaction to Flu vaccine continue they usually begin soon after the shot and last 1-2 days. Severe Flu Shot Reactions. Severe Flu shot reactions include allergic reactions. CDC says however that a life-threatening reaction to Flu vaccine is very rare. If Flu shot reactions occur, it is usually within a few minutes to a few hours after the vaccine.
Mild systemic symptoms, such as nausea, lethargy, headache, muscle aches, and chills, can occur. These symptoms are more common after the nose-spray version of the flu vaccine (more on this below). The side effects of the flu vaccine are mild (and nothing compared to having the flu). The most common side effects are local pain and tenderness. Fever is also seen within 24 hours after immunization in approximately 10 to 35 percent of children younger than 2 years of age, but rarely in older children and adults.