Demodectic Mange in Dogs. Save to mypetMD. Mange (demodicosis) is an inflammatory disease in dogs caused by various types of the Demodex mite. When the number of mites inhabiting the hair follicles and skin of the dog become exorbitant, it can lead to skin lesions, genetic disorders, problems with the immune system and hair loss (alopecia).
Osteoclasts are found on top of or next to existing bone tissue, sometimes in close proximity to osteoblasts. There is on-going race between the two cell types; osteoblasts make bone tissue while osteoclasts reabsorb it.
An osteoclast is a large multinucleated cell and human osteoclasts on bone typically have five nuclei and are about 150-200 Âµm in diameter. When osteoclast-inducing cytokines are used to convert macrophages to osteoclasts, very large cells that may reach 100 Âµm in diameter occur.