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A typical dose of prednisone for the average size adult is prednisone 20 mg twice a day for 7-10 days followed by 20 mg a day in the morning for 3 days. That program should be adequate to treat most cases of poison ivy. typical dose of prednisone for the average size adult is prednisone 20 mg twice a day for 7-10 days followed by 20 mg a day in the morning for 3 days. That program should be adequate to treat most cases of poison ivy.
It is possible that your dose of prednisone may need to be adjusted after considering the other medications or supplements you take. 1  Depending on the condition being treated, a starting dose between 5 mg and 60 mg per day of prednisone is not uncommon. The dose is further adjusted based on treatment response.