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1. Cystic fibrosis is an autosomal recessive genetic disorder. Cystic fibrosis (CF) is an autosomal recessive disease that affects many body systems.It is caused by mutations to the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Located on human chromosome 7, the CFTR gene is made up of 250,000 DNA nucleotides.. Cystic fibrosis is an autosomal recessive genetic disorder. Cystic fibrosis (CF) is an autosomal recessive disease that affects many body systems.
1 Cystic fibrosis primarily affects the lungs and digestive system. 2  It leads to the production of mucus that is much thicker and more sticky than usual. 3  Cystic fibrosis is a hereditary condition, caused by a defective gene. 4  The cystic fibrosis gene must be present in both parents for a child to have the condition. It leads to the production of mucus that is much thicker and more sticky than usual. 2  Cystic fibrosis is a hereditary condition, caused by a defective gene. 3  The cystic fibrosis gene must be present in both parents for a child to have the condition.