1 A physical change, such as a state change or dissolving, does not create a new substance, but a chemical change does. 2  In a chemical reaction, the atoms and molecules that interact with each other are called reactants. 3  In a chemical reaction, the atoms and molecules produced by the reaction are called products. In a chemical reaction, the atoms and molecules produced by the reaction are called products. 2  In a chemical reaction, only the atoms present in the reactants can end up in the products. 3  No new atoms are created, and no atoms are destroyed.
Humira (adalimumab) is a biologic drug that works by blocking a protein known as TNF-alpha. Normally, TNF-alpha helps fight infection, but in excess amounts, it can cause painful inflammation and severe joint damage -- common symptoms of rheumatoid arthritis and other forms of inflammatory arthritis.
For ulcerative colitis, Humira is approved when other drugs to suppress immune responses haven't worked. Each patient with ulcerative colitis experiences the disease differently, and treatment must be adjusted to meet each individualâs needs, says Donna Griebel, MD, director of the FDA's gastroenterology division.