To make sure glyburide and metformin is safe for you, tell your doctor if you have: 1  kidney disease; 2  an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD); 3  liver disease; or.  heart disease or a history of heart attack or stroke.
The importance of siblings. 'My sister and I are very close and weâre in touch a lot, yet itâs not an easy relationshipâ, says Marie, 36, of her sister Kate, who is two years older. âOften Iâll come off the phone feeling irritated and somehow dissatisfied. A sibling relationship is likely to be the most enduring of our lives. The impact they have on our young and adult lives is enormous â they shape our history and our character, to a far greater extent than is usually acknowledged.
Furthermore, the connection between the parent-child. relationship, which is characterized both by the qualities of that relationship and the ways in. which the parents manage sibling conflicts, and the sibling relationship, which is characterized. by the four relationship factors, is bi-directional in nature.