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Mild Flu Shot Reactions. Mild Flu shot reactions include soreness, redness or swelling where the shot was given, hoarseness; sore, red or itchy eyes; cough, fever, and aches. A reaction to Flu vaccine continue they usually begin soon after the shot and last 1-2 days. Severe Flu Shot Reactions. Severe Flu shot reactions include allergic reactions. CDC says however that a life-threatening reaction to Flu vaccine is very rare. If Flu shot reactions occur, it is usually within a few minutes to a few hours after the vaccine.
Quick Answer. The side effects of a pneumonia vaccine include high fever, significant swelling at the injection site and sore muscles, according to WebMD. Some people may have an allergic reaction to the vaccine and experience serious side effects such as hives, dizziness, trouble breathing and fast heartbeats. Continue Reading.