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Answer Wiki. Some knots can come out within a couple minutes. Others never come out. I've had extreme back and neck pain for the past year and a half, most of it just tension in my muscles. I've had numerous massages, taken other treatment, all to no avail.
These little, irritating bubbles are caused by chronic myofascial pain, which is felt in particularly sensitive trigger points in the body. When this kind of pain doesn't go away, the muscle can swell and harden into a bump (or knot). Although there's no scientific consensus on why these knots form, we know they tend to show up after the muscle is injured or strained due to repetitive motions. And, they often occur in the shoulders, back, or neck.