The ONLY way to produce a tiger or lion with a white coat is through inbreeding brother to sister or father to daughter; generation after generation after generation. The kind of severe inbreeding that is required to produce the mutation of a white coat also causes a number of other defects in these big cats.
Causes of Bumps on Skin. 1  Acne (Pimples) Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. 2  Actinic Keratosis Actinic keratoses are rough, scaly patches of skin that are considered precancerous and are due to sun exposure.
What causes uneven skin tone? The main causes of uneven skin tone are hyperpigmentation, sun spots, hormones and discolouration due to acne scarring. An excess of melanin or pigment in the skin due to sun exposure creates freckles and eventually, isolated dark spots.