1 One form of Stickler syndrome is due to mutation in the COL2A1 gene on chromosome 12 in region 12q13.11-q13.2. It is termed Stickler syndrome, type I and symbolized STL1.  A second form of Stickler syndrome is caused by mutation in the COL11A1 gene on chromosome 1 in region 1p21.
Recent technical advances in this field will give rise to conceptual advances and there is every reason to believe that a new field of cancer genetics is emerging, named here Oncogenetics: a branch of genetics describing the cause of effects of genes causing neoplasia.
Onco-, from the Greek onkos, meaning âbulk,â or âmass,â refers to the tumour-causing ability of the oncogene, which is apt, but the term proto-oncogene stresses the potential the gene has to become a malignant force, rather than its integral role as a regulator of cell activity.