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Pulmonary hypertension is high blood pressure within the artery that connects the lungs and heart. It forces the heart to work harder to transfer blood between the heart and lungs, which may lead to an enlargement of the right side. Thyroid problems, whether they involve an underactive or overactive thyroid, can cause a heart to enlarge.
The pain experienced is a sharp stabbing sensation in the chest. At times, the pain may radiate to the arms, shoulders, jaw and/or neck. Disorders related to the digestive system, like gallstones or inflammation of the liver, can also cause pain in the right side of the chest.