TOPROL-XL administered once a day, and immediate-release metoprolol administered once to four times a day, provided comparable total beta 1 -blockade over 24 hours (area under the beta 1 -blockade versus time curve) in the dose range 100-400 mg.
Antimicrobial: A drug used to treat a microbial infection. Antimicrobial is a general term that refers to a group of drugs that includes antibiotics, antifungals, antiprotozoals, and antivirals.
1. destructive of life. 2. a chemical substance produced by a microorganism that has the capacity, in dilute solutions, to kill other microorganisms or inhibit their growth. Antibiotics that are sufficiently nontoxic to the host are used as chemotherapeutic agents in the treatment of infectious diseases.See also antimicrobial agent.ntibiotic (anÂ´tibÄ«otÂ´ik) , n an organic substance produced by one of several microorganisms, especially certain molds, that is capable, in low concentration, of destroying or inhibiting the growth of certain other microorganisms.