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Necrotizing soft tissue infection (NSTI) is a broad term applied to infections of âflesh eating bacteriaâ that. may cause cellulitis, fasciitis, or myositis. NSTIâs can rapidly progress to systemic toxicity, resulting in. major morbidity and mortality without prompt recognition and treatment. This guideline reviews.
Background. Latent tuberculosis infection (LTBI), defined as a state of persistent immune response to prior-acquired Mycobacterium tuberculosis antigens without evidence of clinically manifested active TB, affects about one-third of the worldâs population.urrently available treatments have an efficacy ranging from 60% to 90%. Systematic testing and treatment of LTBI in at-risk populations is a critical component of WHOâs eight-point framework adapted from the End TB Strategy to target pre-elimination and, ultimately, elimination in low incidence countries.