Definition of NEUROFIBRILLARY TANGLE. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.weet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.
Stephen King Books In Order. On April 5, 1974, Stephen King released Carrie â the first of his novels to be published. Since then, heâs released more than 100 books, novellas, short stories, poems and screenplays, selling more than 350 million copies in the process.
Harry Potter and the Philosopherâs Stone is the first in the series of Harry Potter novels by J.K. Rowling. It was published in the U.S. as Harry Potter and the Sorcererâs Stone a year after being published in the UK. first British printing: July 1, 1997, Bloomsbury Books. first American printing: September 1, 1999, Scholastic, Arthur A. Levine Books. U.S. illustrations by Mary GrandPrÃ©, 1998.