NPH insulin has the advantage that it can be mixed with an insulin that has a faster onset to complement its longer lasting action, which is the primary reason NPH remains on the market today, because manufacturers sell a variety of premixed insulin formulations.
Wrap the foil tightly around the brisket to seal in heat and moisture while it cooks. Place the baking dish with the aluminum-wrapped brisket in the oven and bake for around one hour per pound of meat. Increase cooking time to 90 minutes per pound if you are cooking larger cuts of brisket, those weighing 8 to 12 pounds.
1 Place in the oven and cover. 2  Cook until tender 3-4 hours. 3  Baste every 30 minutes to an hour. 4  If you run out of liquid add a bit more beef stock. 5  The brisket should be easy to cut and fall apart when you pull at it with a fork.6  Take out of the oven and let rest for at least 30 minutes. Place in the oven and cover. 2  Cook until tender 3-4 hours. 3  Baste every 30 minutes to an hour. 4  If you run out of liquid add a bit more beef stock. 5  The brisket should be easy to cut and fall apart when you pull at it with a fork.