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The four most common teratogens are  tobacco, alcohol, medications and illegal drugs. Teratogens are substances that could harm a developing fetus by affecting growth and causing birth defects or death.
A teratogen is a drug or other substance capable of interfering with the development of an embryo fetus that may lead to birth defects. Developing embryo is highly sensitive to teratogens during weeks 3 to 9 of pregnancy.