The ONLY way to produce a tiger or lion with a white coat is through inbreeding brother to sister or father to daughter; generation after generation after generation. The kind of severe inbreeding that is required to produce the mutation of a white coat also causes a number of other defects in these big cats.
Causes of Bumps on Skin. 1  Acne (Pimples) Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. 2  Actinic Keratosis Actinic keratoses are rough, scaly patches of skin that are considered precancerous and are due to sun exposure.
Common causes of skin changes include: 1  Skin puckering or dimpling. 2  Skin puckering or dimpling can be caused by scarring from a previous operation or infection, but in the majority of cases, no specific reason can be found. 3  Most often it is not a sign of underlying cancer, but should be evaluated with exam and imaging.