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Answer Wiki. Some knots can come out within a couple minutes. Others never come out. I've had extreme back and neck pain for the past year and a half, most of it just tension in my muscles. I've had numerous massages, taken other treatment, all to no avail.
If muscle knots are chronic or donât respond to massage, it may be time to see your doctor. Injections of lidocaine or corticosteroids to the knot and surrounding muscle tissues induce the fibers to relax. This option is also good for dealing with trigger points that occur after an accident or injury to the muscle.