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But denosumab is a first-in-class drug: It's a biologic, which means it will likely be much more expensive than its competitor drugs, some of which are available as cheaper generics. The drug also boasts an extremely convenient dosing regimen -- subcutaneous injection every six months.
Virtually all drugs carry possible side effects. Biologics for the treatment of RA are no different. As seen above, biologics work in a number of different ways to reduce inflammation. They all interfere with some aspect of immune system function, though.For this reason, people taking a biologic drug may be at greater risk for certain infections.hese modern âbiologicsâ have greatly improved the effectiveness of treatment for many RA patients. Unlike older disease-modifying anti-rheumatic drugs (DMARDs), biologic DMARDs are made using biotechnology. They are genetically engineered to behave like natural immune system proteins.