Nail discoloration, in which the nails appear white, yellow, or green, can result from different infections and conditions of the skin. In about 50% of cases, discolored nails are a result of infections with common fungi that can be found in the air, dust, and soil.
Doxycycline is well absorbed. After an oral dose of 200 mg of doxycycline, plasma concentrations of the drug reach a maximum of 3 micrograms/mL at 2 hours and are well maintained and thus dosage once daily is usually adequate. Absorption is diminished by the presence of iron, aluminium, calcium and magnesium. Doxycycline is widely distributed into pleural and peritoneal fluid, saliva, semen and prostatic fluid. It passes the placental barrier readily and is also present in the milk of lactating patients.
Cardiac tamponade is usually the result of penetration of the pericardium, which is the thin, double-walled sac that surrounds your heart. The cavity around your heart can fill with enough blood or other bodily fluids to compress your heart. As the fluid presses on your heart, less and less blood can enter. Less oxygen-rich blood is pumped to the rest of your body as a result. The lack of blood getting to the heart and the rest of your body can eventually cause shock, organ failure, and cardiac arrest. The causes of pericardial penetration or fluid accumulation might include: