1 One form of Stickler syndrome is due to mutation in the COL2A1 gene on chromosome 12 in region 12q13.11-q13.2. It is termed Stickler syndrome, type I and symbolized STL1.  A second form of Stickler syndrome is caused by mutation in the COL11A1 gene on chromosome 1 in region 1p21.
Recent technical advances in this field will give rise to conceptual advances and there is every reason to believe that a new field of cancer genetics is emerging, named here Oncogenetics: a branch of genetics describing the cause of effects of genes causing neoplasia.
Oncogenes are damaged versions of normal genes called proto-oncogenes proto-oncogenesA normal gene involved in the control of cell growth and division that can mutate (change) and become an oncogene. Mutations can be inherited or caused by exposure to a carcinogen (a substance that causes cancer) in the environment. .