Sickle cell disease occurs from genetic changes that cause abnormalities in hemoglobin molecules: 1  Hemoglobin A (HbA) . 2  HbA is the hemoglobin molecule found in normal red blood cells during childhood and adulthood. 3  People who do not have sickle cell disease generally have this type of hemoglobin in their blood cells.ickle cell disease is an inherited blood disorder in which the body produces abnormally shaped red blood cells. In sickle cell disease, the hemoglobin in red blood cells clumps together. This causes red blood cells to become stiff and C-shaped.
A few new pregnancy symptoms will be noticed with the rise and fall of hormonal levels when you are 2 months pregnant. Your waistline is increasing even though you have not put on any significant weight. There is a change in the texture of the hair and skin during pregnancy.
If your baby is overdue. Pregnancy normally lasts about 40 weeks (that's around 280 days from the first day of your last period).Most women go into labour a week either side of this date, but some women go overdue.If your labour doesn't start by the time you are 40 weeks pregnant, and this is your first pregnancy, your midwife will offer you a membrane sweep at your 40 and 41 weeks appointments.If you have had a baby before, you will be offered this just at your 41 weeks appointment.f your labour doesn't start by the time you are 40 weeks pregnant, and this is your first pregnancy, your midwife will offer you a membrane sweep at your 40 and 41 weeks appointments.