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But denosumab is a first-in-class drug: It's a biologic, which means it will likely be much more expensive than its competitor drugs, some of which are available as cheaper generics. The drug also boasts an extremely convenient dosing regimen -- subcutaneous injection every six months.
Cost could be seen as an obstacle for patients considering Prolia as a treatment option. While generic Fosamax costs roughly $100 to $200 per year and brand-name bisphosphonates slightly less than $1,000 per year, Prolia will cost about $1,650 per year plus the cost associated with an office visit.Prolia is also more expensive than Reclast, which costs $1,100 for a yearly dose.But Siris notes that Prolia will be covered under Medicare Part B, so the cost will likely be covered by the healthcare system rather than by many patients receiving this treatment.ol. 3 No. 4 P. 6. Healthcare providers involved in the fight against osteoporosis now have one more weapon in their arsenal, as the FDA recently approved the sale of Prolia (denosumab), a twice-yearly injection indicated for postmenopausal women.