1 One form of Stickler syndrome is due to mutation in the COL2A1 gene on chromosome 12 in region 12q13.11-q13.2. It is termed Stickler syndrome, type I and symbolized STL1.  A second form of Stickler syndrome is caused by mutation in the COL11A1 gene on chromosome 1 in region 1p21.
Recent technical advances in this field will give rise to conceptual advances and there is every reason to believe that a new field of cancer genetics is emerging, named here Oncogenetics: a branch of genetics describing the cause of effects of genes causing neoplasia.
âEpigeneticsâ refers to covalent modification of DNA, protein, or RNA, resulting in changes to the function and/or regulation of these molecules, without altering their primary sequences.n some cases, epigenetic modifications are stable and passed on to future generations, but in other instances they are dynamic and change in response to environmental stimuli. Nearly every aspect of biology is influenced by epigenetics, making it one of the most important fields in science.