English Collins Dictionary - English synonyms & Thesaurus. ( rejigs 3rd person present) ( rejigging present participle) ( rejigged past tense & past participle ) If someone rejigs an organization or a piece of work, they arrange or organize it in a different way, in order to improve it. (BRIT) verb. ...adjustments needed to rejig the industry.
Agonist: A substance that acts like another substance and therefore stimulates an action. Agonist is the opposite of antagonist. Antagonists and agonists are key players in the chemistry of the human body and in pharmacology. Last Editorial Review: 5/13/2016.
An inverse agonist is an agent that binds to the same receptor binding-site as an agonist for that receptor and inhibits the constitutive activity of the receptor. Inverse agonists exert the opposite pharmacological effect of a receptor agonist, not merely an absence of the agonist effect as seen with antagonist.An example is the cannabinoid inverse agonist rimonabant. A co-agonist works with other co-agonists to produce the desired effect together.ull agonists bind (have affinity for) and activate a receptor, producing full efficacy at that receptor. One example of a drug that acts as a full agonist is isoproterenol, which mimics the action of adrenaline at Î² adrenoreceptors.