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Bactrim is a sulfa-based antibiotic and is not a penicillin-based medicine, according to RxList. However, a patient should discuss all allergies with a doctor to determine what drugs can and cannot be taken. Continue Reading.
Bactrim Â® (sulfamethoxazole/trimethoprim) is a prescription antibiotic approved to treat a variety of different infections. In addition to treating infections, it is also approved to prevent one particular infection, Pneumocystis carinii pneumonia, in people with a weakened immune system.actrim contains two different antibiotics, sulfamethoxazole and trimethoprim. Sulfamethoxazole belongs to a group of drugs known as sulfonamides (sulfa drugs). Trimethoprim does not belong to a specific class of medications. These two antibiotics work in different but similar ways.