#1 of 3 B&Bs / Inns in Chenonceaux. â 1  Lives up to all its recommendations 2  â. We were welcomed to the maison with a smile and a much appreciated cup of... more. 3  December 16, 2016.
Induced fit hypothesis. Daniel Koshland's theory of enzyme-substrate binding is that the active site and the binding portion of the substrate are not exactly complementary. The induced fit model is a development of the lock-and-key model and assumes that an active site is flexible and it changes shape until the substrate is completely bound. The substrate is thought to induce a change in the shape of the active site.
however induced fit says the active site will change to help to substrate fit in lock and key the active site has one single entry however in induced fit the active site is made of two components this is the idea that only the correctly sized substrate key fits into the active site key hole of the enzyme lock