Nail discoloration, in which the nails appear white, yellow, or green, can result from different infections and conditions of the skin. In about 50% of cases, discolored nails are a result of infections with common fungi that can be found in the air, dust, and soil.
Doxycycline is well absorbed. After an oral dose of 200 mg of doxycycline, plasma concentrations of the drug reach a maximum of 3 micrograms/mL at 2 hours and are well maintained and thus dosage once daily is usually adequate. Absorption is diminished by the presence of iron, aluminium, calcium and magnesium. Doxycycline is widely distributed into pleural and peritoneal fluid, saliva, semen and prostatic fluid. It passes the placental barrier readily and is also present in the milk of lactating patients.
Removing the fluid (thoracentesis) may be done if there is a lot of fluid and it is causing chest pressure, shortness of breath, or other breathing problems, such as a low oxygen level. Removing the fluid allows the lung to expand, making breathing easier. The cause of the fluid buildup must also be treated. If it is due to congestive heart failure, you may receive diuretics (water pills) and other medications to treat heart failure. Pleural effusion caused by infection is treated with antibiotics.