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The four most common teratogens are  tobacco, alcohol, medications and illegal drugs. Teratogens are substances that could harm a developing fetus by affecting growth and causing birth defects or death.
Effects of teratogens during this period of developmental often times results in an âall or none effect.â That is, the effect of the teratogen, if it is to have any effect, will be so profound as to cause a spontaneous abortion. Some examples of teratogens known to cause human malformations are listed in the table below (Table 23-2). A few of the most common examples will be discussed below.