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You can take amoxicillin with or without food. A common dose of amoxicillin for an adult with a mild to moderate ear, nose, or throat infection is 500 mg every 12 hours or 250 mg every 8 hours until the prescription is finished. For a more severe infection, a common dose of amoxicillin is 875 mg every 12 hours or 500 mg every 8 hours. A common dose of amoxicillin for a child (older than 3 months) with a lower respiratory tract infection is 40 mg per kilogram (kg) of weight per day in divided doses every 8 hours. Or, doctors sometimes want the child to take 45 mg per kg per day in divided doses every 12 hours.
Children 2 months to 6 years old should be given 80 to 90 mg of amoxicillin per kilogram of body weight per day, divided into two or three doses and taken for 10 days. For instance, if a 2-year-old child weighs 25 pounds, that is about 11 kg.