Sickle cell disease occurs from genetic changes that cause abnormalities in hemoglobin molecules: 1  Hemoglobin A (HbA) . 2  HbA is the hemoglobin molecule found in normal red blood cells during childhood and adulthood. 3  People who do not have sickle cell disease generally have this type of hemoglobin in their blood cells.ickle cell disease is an inherited blood disorder in which the body produces abnormally shaped red blood cells. In sickle cell disease, the hemoglobin in red blood cells clumps together. This causes red blood cells to become stiff and C-shaped.
A few new pregnancy symptoms will be noticed with the rise and fall of hormonal levels when you are 2 months pregnant. Your waistline is increasing even though you have not put on any significant weight. There is a change in the texture of the hair and skin during pregnancy.
As you enter your second trimester of pregnancy, the morning sickness and fatigue that plagued you during the last three months should be fading, leaving you feeling more energetic and like your old self again. The second trimester is, for many women, the easiest three months of pregnancy. Take the time now, while you're feeling better and your energy is up, to start planning for your baby's arrival. During the second trimester, your baby is growing quickly. Between your 18th and 22nd week of pregnancy you'll have an ultrasound so your doctor can see how your baby is progressing. You also can learn the sex of your baby, unless you'd rather be surprised.