NPH insulin has the advantage that it can be mixed with an insulin that has a faster onset to complement its longer lasting action, which is the primary reason NPH remains on the market today, because manufacturers sell a variety of premixed insulin formulations.
Wrap the foil tightly around the brisket to seal in heat and moisture while it cooks. Place the baking dish with the aluminum-wrapped brisket in the oven and bake for around one hour per pound of meat. Increase cooking time to 90 minutes per pound if you are cooking larger cuts of brisket, those weighing 8 to 12 pounds.
Estimated Cooking Time. How long will it take to cook brisket to 200-205 F? As a rough estimate, assuming a cooker temp of 225-250Â°F, figure 1 hour to 1 hour 30 minutes per pound for a whole, packer brisket weighing 12 pounds after trimming any excess fat.hole, untrimmed briskets weigh 8-20 pounds. A brisket about 12 pounds fits easily on either WSM cooking grate. Briskets larger than 12 pounds can be shoehorned between the handles on the cooking grate and will shrink during cooking.