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But denosumab is a first-in-class drug: It's a biologic, which means it will likely be much more expensive than its competitor drugs, some of which are available as cheaper generics. The drug also boasts an extremely convenient dosing regimen -- subcutaneous injection every six months.
Common side effects of Prolia include low calcium levels (especially if you have kidney problems), weakness, constipation, back pain, muscle pain, pain in your arms and legs, anemia, diarrhea, or skin problems (eczema, blisters, dry skin, peeling, redness, itching, small bumps).rolia should be administered by a doctor. The recommended dose of Prolia is 60 mg administered as a single subcutaneous (under the skin) injection once every 6 months. The effects of some drugs can change if you take other drugs or herbal products at the same time.