#1 of 3 B&Bs / Inns in Chenonceaux. â 1  Lives up to all its recommendations 2  â. We were welcomed to the maison with a smile and a much appreciated cup of... more. 3  December 16, 2016.
Induced fit hypothesis. Daniel Koshland's theory of enzyme-substrate binding is that the active site and the binding portion of the substrate are not exactly complementary. The induced fit model is a development of the lock-and-key model and assumes that an active site is flexible and it changes shape until the substrate is completely bound. The substrate is thought to induce a change in the shape of the active site.
lock and key hypothesis vs induced fit theory similarities both say only one substrate will work when it meets the active site of the enzyme both require an enzyme and a substrate differences lock and key states that there is no change needed and that only a certain type will fit