Nail discoloration, in which the nails appear white, yellow, or green, can result from different infections and conditions of the skin. In about 50% of cases, discolored nails are a result of infections with common fungi that can be found in the air, dust, and soil.
Doxycycline is well absorbed. After an oral dose of 200 mg of doxycycline, plasma concentrations of the drug reach a maximum of 3 micrograms/mL at 2 hours and are well maintained and thus dosage once daily is usually adequate. Absorption is diminished by the presence of iron, aluminium, calcium and magnesium. Doxycycline is widely distributed into pleural and peritoneal fluid, saliva, semen and prostatic fluid. It passes the placental barrier readily and is also present in the milk of lactating patients.
Normally the peritoneal cavity contains no fluid, although in women a small amount (20ml, or less than an ounce) can occasionally be found depending on the menstrual cycle. Ascites is the term used to denote a fluid collection in the peritoneal cavity, a situation that is not normal. There are a variety of diseases that can cause the fluid to accumulate and the reasons that the ascites occurs may be different for each disease.