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NON-DOT TESTING. A dilute specimen, by definition, is a urine specimen that has a creatinine of less than 20 g/dl and a specific gravity of 1.003 or less. These 2 tests are routinely performed on every urine sample that is tested at the Lab. If the specimen meets the above 2 criteria, it is reported as a Dilute specimen.
Because the creatinine is excreted from the body at a constant rate, there are expected values for creatinine in normal human urine. Specimen validity testing is the evaluation of the specimen to determine if it is consistent with normal human urine (creatinine values greater than 20 mg/dL). When abnormally large quantities of fluids are consumed, the urine becomes diluted and the creatinine levels are substantially reduced.