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Causes of sepsis. Sepsis can be triggered by an infection in any part of the body. The most common sites of infection leading to sepsis are the lungs, urinary tract, tummy (abdomen) and pelvis. Sepsis may develop when you're already in hospital. For example, you're more likely to develop sepsis if:
Possible cause. The low blood pressure and inflammation patients experience during sepsis may lead to brain damage that causes cognitive problems. Sepsis patients also frequently become delirious, a state known to be associated with Alzheimer's disease.t can start as a reaction to an infection, such as pneumonia, and go on to damage the body itself. When organs are damaged, the condition is known as severe sepsis. Sepsis affects hundreds of thousands of patients each year, and about 40 percent of people with the illness die from it.