Prednisone is intended for oral administration only. Adults: The initial dose is 5mg to 80mg daily depending on the condition being. treated, as a single dose after breakfast, as divided doses, or as a double dose on. alternate days. The maintenance dose is usually 5mg to 20mg daily. The dose should. be individualised according to the severity of the disease and the patients response. rather than by age or body weight. For adrenogenital syndrome: 5 to 10mg a day as a single dose. The usual adult prescribing limit is up to 250mg day.
View/Edit Mouse. Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels.
ActivaseÂ® (Alteplase), also known as t-PA, is a tissue plasminogen. activator produced by recombinant DNA technology. Activase belongs to. the thrombolytic class of drugs and is the first drug to be indicated for the. management of acute ischemic stroke. All thrombolytic agents increase the. risk of bleeding, including intracranial bleeding, and should be used only. in appropriate patients. Not all patients with acute ischemic stroke will be. eligible for Activase therapy, as defined by the following indication. and contraindications. Please see accompanying full prescribing information for additional. Important Safety Information.