Demodectic Mange in Dogs. Save to mypetMD. Mange (demodicosis) is an inflammatory disease in dogs caused by various types of the Demodex mite. When the number of mites inhabiting the hair follicles and skin of the dog become exorbitant, it can lead to skin lesions, genetic disorders, problems with the immune system and hair loss (alopecia).
Osteoblast, large cell responsible for the synthesis and mineralization of bone during both initial bone formation and later bone remodeling. Osteoblasts form a closely packed sheet on the surface of the bone, from which cellular processes extend through the developing bone. They arise from the differentiation of osteogenic cells in the periosteum, the tissue that covers the outer surface of the bone, and in the endosteum of the marrow cavity. This cell differentiation requires a regular supply of blood, without which cartilage-forming chondroblasts, rather than osteoblasts, are formed.
One of the largest determinants in bone health is the ability for the cells in the process of bone building to actively continue to break down old bone and produce new bone. There are two cells in bone responsible for building bones: osteoblasts and osteoclasts.An osteoblast (from the Greek âOsteoâ meaning âboneâ and âblastâ meaning âgermâ or âembryonic) create new bone and an osteoclast breaks down and recycles old bone.here are two cells in bone responsible for building bones: osteoblasts and osteoclasts. An osteoblast (from the Greek âOsteoâ meaning âboneâ and âblastâ meaning âgermâ or âembryonic) create new bone and an osteoclast breaks down and recycles old bone.