1 on/under pain of death idiom. 2  a pain in the arse/backside idiom. 3  a pain in the ass/butt, at a pain in the arse/backside idiom.  a pain (in the neck) idiom.
In addition to the differences in replication method, transmission risk is higher with Hep B as it can be sexually transmitted, whereas generally not with Hep C. The large majority of adult patients exposed to Hep B clear it, whereas with Hep C adults who are exposed and clear are the minority.
Thus, four hypotheses are possible: 1, APRV/BIPAP is better than A/C; 2, APRV/BIPAP is worse than A/C; 3, there is no difference between APRV/BIPAP and A/C; 4, it is undetermined whether there is a difference between APRV/BIPAP and A/C.