Demodectic Mange in Dogs. Save to mypetMD. Mange (demodicosis) is an inflammatory disease in dogs caused by various types of the Demodex mite. When the number of mites inhabiting the hair follicles and skin of the dog become exorbitant, it can lead to skin lesions, genetic disorders, problems with the immune system and hair loss (alopecia).
Osteoclasts are found on top of or next to existing bone tissue, sometimes in close proximity to osteoblasts. There is on-going race between the two cell types; osteoblasts make bone tissue while osteoclasts reabsorb it.
os'teÂ·oÂ·clas'tic adj. osteoclast. A specialized bone cell that absorbs bone, allowing for the deposition of new bone and maintenance of bone strength. Osteoclasts secrete enyzmes that dissolve the matrix of old bone tissue and acids that dissolve bone salts, which contain calcium and phosphorus. Except in growing bone, the rate of bone deposition and bone absorption equal each other so that bone mass remains constant. A mass of osteoclasts absorbs bone from the outer surfaces inward for about three weeks.