The PT and INR are used to monitor the effectiveness of the anticoagulant warfarin. This drug affects the function of the coagulation cascade and helps inhibit the formation of blood clots. It is prescribed on a long-term basis to people who have experienced recurrent inappropriate blood clotting.
IRS Rules on Prototype and Volume Submitter Plans. August 5, 2008. In 2005, sponsors of prototype and volume submitter retirement plan documents were required to update their documents for the Economic Growth Tax Relief and Reconciliation Act of 2001 (âEGTRRAâ) and file these updated documents with the IRS.
A request for a proposal file update automatically will be accepted if submitted prior to: 1  the deadline date specified in a program solicitation; 2  initiation of external peer review in cases when a target date is utilized; and. 3  initiation of external peer review in the case of an unsolicited proposal.