Definition of NEUROFIBRILLARY TANGLE. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.weet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.
Stephen King Books In Order. On April 5, 1974, Stephen King released Carrie â the first of his novels to be published. Since then, heâs released more than 100 books, novellas, short stories, poems and screenplays, selling more than 350 million copies in the process.
Harry Potter and the Sorcerers Stone (Book One) was published by Scholastic Press; First American edition in October 1998. Dennis Rigsby. Harry Potter and the Sorcerer's Stone (Book 1) came out in 1998 by J.K. Rowling.