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But denosumab is a first-in-class drug: It's a biologic, which means it will likely be much more expensive than its competitor drugs, some of which are available as cheaper generics. The drug also boasts an extremely convenient dosing regimen -- subcutaneous injection every six months.
Biologics, instead, target specific parts of the immune system. The biologics used to treat psoriatic disease block the action of a specific type of immune cell called a T cell, or block proteins in the immune system, such as tumor necrosis factor-alpha (TNF-alpha), interleukin 17-A, or interleukins 12 and 23.iologics are prescribed for individuals with moderate to severe cases of plaque psoriasis and psoriatic arthritis. They are a viable option for those who have not responded to or have experienced harmful side effects from other treatments.