Sponsored Topics. Oaktown is a town in Busseron Township, Knox County, Indiana, United States. The population was 608 at the 2010 census. Oaktown is located at 38Â°52â²17â³N 87Â°26â²25â³W / 38.87139Â°N 87.44028Â°W / 38.87139; -87.44028 (38.871331, -87.440163).
The pathophysiology of rheumatoid arthritis is mediated by an inter-related network of cytokines, proteolytic enzymes and prostanoids. IL-1, TNF-alpha, etc. are proinflammatory cytokines and are the central mediators in the disease.he pathophysiology of rheumatoid arthritis is mediated by an inter-related network of cytokines, proteolytic enzymes and prostanoids. IL-1, TNF-alpha, etc. are proinflammatory cytokines and are the central mediators in the disease.
Arthritis means joint inflammation. The joint inflammation of rheumatoid arthritis causes swelling, pain, stiffness, and redness in the joints. The inflammation of rheumatoid disease can also occur in tissues around the joints, such as the tendons, ligaments, and muscles.In some people with rheumatoid arthritis, chronic inflammation leads to the destruction of the cartilage, bone, and ligaments, causing deformity of the joints.heumatoid arthritis (RA or atrophic arthritis) facts. 1  Rheumatoid arthritis is an autoimmune disease that can cause chronic inflammation of the joints and other areas of the body. 2  Rheumatoid arthritis symptoms and signs include. 3  joint pain in the feet, hands, and knees, 4  swollen joints, 5  fever, 6  tender joints,