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Pulmonary hypertension is high blood pressure within the artery that connects the lungs and heart. It forces the heart to work harder to transfer blood between the heart and lungs, which may lead to an enlargement of the right side. Thyroid problems, whether they involve an underactive or overactive thyroid, can cause a heart to enlarge.
Causes of Dextrocardia. The cause of dextrocardia is unknown. The heart may form in the right side of the chest during fetal development and function normally. This is usually the case when the heart is a âmirror imageâ of a normal heart. In other words, the heartâs ventricles, arteries, and other structures are all arranged in a mirror image of normal heart structures.