Nextdoor is the private social network for your neighborhood. On Nextdoor, neighbors create private groups for their neighborhoods where they can ask questions, get to know one another, and exchange local advice and recommendations.
Up-regulation is a process that occurs within a cell triggered by a signal (originating internal or external to the cell), which results in increased expression of one or more genes and as a result the protein(s) encoded by those genes.
Eukaryotes share a number of proteins which regulate the cell cycle, such as cyclins, kinases, phosphatases, growth factors, and their receptors. Some proteins which are involved in the initiation of the eukaryotic cell cycle may have homologs in bacteria, such as Cdc6/Cdc18, MCMs, and Cdc45 (Leatherwood, 1998).