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Responses (1) takes 24 hours for antibiotic to start working but it could take several days to feel better. You didnt say why you were taking it, it is used alot for urinary tract infections and bladder infections. If this is the case you should drink as much water as you can and this will help also.
If you get the right antibiotic it can be as little as 2 doses - 24 hours for the swelling to goâ¦ down. Sometimes it can take 3 or 4 doses to go down - about 48 hours. If you have been on an antibiotic for 3 days and there is no change in the swelling, you should call your doctor. You may need a stronger antibiotic or a different class of antibiotics.