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The Ohio River ends at the confluence with the Mississippi River at Cairo, Illinois. This confluence borders Kentucky, Illinois and Missouri. Even though the Ohio River is much wider and carries more water than the Mississippi where they meet, the Ohio is considered the tributary to the Mississippi.
The navigable mileage markers for the lower Mississippi begin at the mouth of the river, below New Orleans, and end at the confluence of the Ohio River at Cairo, Illinois. Mile zero for the upper Mississippi begins at Cairo and continues northward to Minneapolis.