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Sclerotic breast cancer metastases in the pelvis. Bone metastases, or metastatic bone disease, is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare.
METASTASIS means one tumor. METASTASES is plural â it means two or more tumors. METASTASIZE is the process of cells traveling through the. body to reach another part of the body. PRIMARY SITE refers to the location of the original cancer. Lung, breast, melanoma (skin cancer), colon and. kidney cancers commonly spread to the brain.