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CCK plays a variety of roles in digestive processes, including inhibition of food intake, consistent with a role in satiety. In the lingual epithelium, the sensing of a broad spectrum of L-amino acids is accomplished by the heteromeric amino acid (umami) taste receptor (T1R1-T1R3).T1R1 and T1R3 subunits are also expressed in the intestine.A defining characteristic of umami sensing by T1R1-T1R3 is its potentiation by IMP or GMP.ensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion.
Taste is the ability to respond to dissolved molecules and ions called tastants. Humans detect taste with taste receptor cells. These are clustered in taste buds and scattered in other areas of the body.Each taste bud has a pore that opens out to the surface of the tongue enabling molecules and ions taken into the mouth to reach the receptor cells inside.1  salty.2  sour. 3  sweet. 4  bitter.5  umami.umans detect taste with taste receptor cells. These are clustered in taste buds and scattered in other areas of the body. Each taste bud has a pore that opens out to the surface of the tongue enabling molecules and ions taken into the mouth to reach the receptor cells inside. 1  salty. 2  sour. 3  sweet. 4  bitter. 5  umami.