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The drugâs initial approval noted mild side effects such as vomiting, itching, lethargy and diarrhea. Some 70 million doses of Trifexis have been distributed through 15,000 veterinary clinics, said Elanco spokeswoman Julie Lawless.
ANAPHYLAXIS: A Severe Allergic Reaction. Anaphylaxis (anna-fih-LACK-sis) is a serious allergic reaction that is rapid in onset and may cause death. Symptoms usually involve more than one organ system (part of the body), such as the skin or mouth, the lungs, the heart, and the gut. Some symptoms include: Skin rashes, itching or hives.