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When someone gets HIV, the body's immune system makes antibodies to try to fight the infection. Most HIV tests available today test for HIV antibodies. If HIV antibodies are present, it means that a person is infected with HIV. One type of HIV test detects the virus itself. This is called an RNA test. RNA testing is more expensive and much less common than antibody tests.
1 Combination tests have been developed that detect HIV antibody and the HIV antigen called the p24 antigen. 2  Levels of p24 antigen are typically high early in the course of infection. 3  A combination test may be performed to increase the likelihood that HIV infection is detected sooner after exposure occurs.ince there is no cure, early treatment of HIV infection and immune system monitoring can greatly improve long-term health and survival. Also, if a person knows his HIV status, it may help change behaviors that can put him and others at risk. Screening. Different types of antibody tests may be used for HIV screening: