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Sclerotic breast cancer metastases in the pelvis. Bone metastases, or metastatic bone disease, is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare.
MetastasisâMetastatic disease is the most common malignant rib lesion [4] (Figs. 6A, and 6B). Most often, the primary neoplasm is in the breast, prostate gland, lung, or kidney. Rib metastases may be osteolytic, sclerotic, or mixed.