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White blood cells known as lymphocytes arise from by mitosis of stem cells in the bone marrow. Some lymphocytes migrate to the thymus and become T cells that circulate in the blood and are associated with the lymph nodes and spleen.
How lymphocytes are made. Some lymphocytes are processed in the bone marrow and then migrate to other areas of the body --- specifically the lymphoid organs (see Lymphatic System). These lymphocytes are called B lymphocytes, or B cells (for bone-marrow-derived cells).hese two types of lymphocytes --- cells and T cells --- play different roles in the immune response, though they may act together and influence one another's functions.