Discourse markers have variant degrees of semantic meaning; they are utterance-initial; and they can signal a discourse relationship or signal a writerâs or a speakerâs attitude. When we are planning to write a well-organized text, cohesion and coherence must be taken into
Koilonychia can also be caused by medical conditions created by unbalanced diets, problems with absorption, inadequate intake of nutrients, inability to digest nutrients, digestive issues, or anything that is capable of hindering the proper development of nails, nail biting included.
Specific causes include: 1  Kostmann's syndrome â a congenital disorder involving low production of neutrophils. 2  Myelokathexis â a congenital disorder involving failure of neutrophils to enter the bloodstream. 3  Leukemia. Myelodysplastic syndromes. 4  Myelofibrosis. Chemotherapy.  Alcohol use 1  disorder. Chronic idiopathic neutropenia in  adults.