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Responses (1) takes 24 hours for antibiotic to start working but it could take several days to feel better. You didnt say why you were taking it, it is used alot for urinary tract infections and bladder infections. If this is the case you should drink as much water as you can and this will help also.
Re: How long do antibiotics take to work? If your tooth has an abcess, the antibiotics alone will not take away the pain. If the infection is so bad that you need a root canal, then I hate to say this, but you will be in some pain until all the infected roots are removed.