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CCK plays a variety of roles in digestive processes, including inhibition of food intake, consistent with a role in satiety. In the lingual epithelium, the sensing of a broad spectrum of L-amino acids is accomplished by the heteromeric amino acid (umami) taste receptor (T1R1-T1R3).T1R1 and T1R3 subunits are also expressed in the intestine.A defining characteristic of umami sensing by T1R1-T1R3 is its potentiation by IMP or GMP.ensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion.
In humans, the chemoreceptors that detect taste are called gustatory receptor cells. About 50 receptor cells, plus basal and supporting cells, make up one taste bud. Taste buds themselves are contained in goblet-shaped papillae -- the small bumps that dot your tongue.ifferent stimuli activate different sensory receptors. Chemical stimuli activate the chemoreceptors responsible for gustatory and olfactory perceptions. Because taste and smell are both reactions to the chemical makeup of solutions, the two senses are closely related.