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There was also a second physician named Bernard Sachs who recognized the familial nature of the disorder and also observed numerous cases. He witnessed that Tay Sachs disease was most common in the European, Jewish origin. Â· When was Tay Sachs disease discovered?Tay Sachs disease was discovered in the year of 1880.
Metabolic refers to the body's chemical processes that produce protein and other substances, and break down nutrients to release energy. Tay-Sachs disease is a metabolic disorder because it is caused by the absence of the enzyme (a type of protein) hexosaminidase A (Hex-A). Hex-A is necessary for breaking down fatty substances called lipids. Without Hex-A, these lipids build up in, and eventually destroy, the nerve cells in the brain.