1 The primer acts as the starting point for DNA synthesis. 2  DNA polymerase binds to the leading strand and then âwalksâ along it, adding new complementary nucleotide bases (A, C, G and T) to the strand of DNA in the 5â to 3â direction. 3  This sort of replication is called continuous.4  Lagging strand: This sort of replication is called continuous. 2  Lagging strand: 3  Numerous RNA primers are made by the primase enzyme and bind at various points along the lagging strand. 4  Chunks of DNA, called Okazaki fragments, are then added to the lagging strand also in the 5â to 3â direction.
Back in Chicago, OKeh Records decided to let Armstrong make his first records with a band under his own name: Louis Armstrong and His Hot Five. From 1925 to 1928, Armstrong made more than 60 records with the Hot Five and, later, the Hot Seven.
Unfortunately, this same year Pilatre de Rozier (the world's first balloonist) was killed in his attempt at crossing the channel. His balloon exploded half an hour after takeoff due to the experimental design of using a hydrogen balloon and hot air balloon tied together. The next major pivotal point in balloon history was on January 7th 1793. Jean Pierre Blanchard became the first to fly a hot air balloon in North America. George Washington was present to see the balloon launch. Now a large jump in time, of over 100 years: In August of 1932 Swiss scientist Auguste Piccard was the first to achieve a manned flight to the Stratosphere.