Hox gene is an example of a homeobox gene. The homeobox sequence codes for a 60 amino acid protein domain known as the homeodomain. The main role of homeodomain is to act as a switch that controls gene transcription.
(Histone modification hassome attributes of an epigenetic process, but the issue ofheritability has yet to be resolved.) This review concernsDNA methylation, focusing on the generation, inheri-tance, and biological significance of genomic methyl-ation patterns in the development of mammals.
As discussed in Chapter 3, DNA replication is a semiconservative process in which each parental strand serves as a template for the synthesis of a new complementary daughter strand.ction of topoisomerases during DNA replication. (A) As the two strands of template DNA unwind, the DNA ahead of the replication fork is forced to rotate in the opposite direction, causing circular molecules to become twisted around themselves.