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Sclerotic breast cancer metastases in the pelvis. Bone metastases, or metastatic bone disease, is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare.
If the cancer has destroyed enough of the bone, these changes appear on x-rays as a darker hole in the gray-white bone image. Osteoblastic or blastic metastases cause an area of the bone to appear denser or sclerotic. On x-rays, these metastases show up as spots that are whiter than the bone around them.This is seen more commonly in certain cancers, such as prostate cancer and some breast cancers. Often, bone metastases have both lytic and blastic features.our doctor may order lab tests and imaging tests (such as x-rays or bone scans) to see how far the cancer has spread. This may be done before, during, and after treatment. These tests may show bone metastases. In other cases, a symptom such as bone pain may be the first sign of bone metastases.