The most common and severe form of Î±1-antitrypsin deficiency is caused by the Z mutation, a single base substitution (Gul342-Lys) in the Î±1-antitrypsin gene. Misfolding of proteins during synthesis can initiate an ordered polymerization, which leads to aggregation of the protein within the cell.
Main article: List of place names of Native American origin in California. 1  Malibu â from VentureÃ±o <Umalibu>, perhaps reflecting [(hu)maliwu], it (the surf) makes a loud noise all the time over there. 2  Pismo Beach - from Chumash Pismu for tar. 3  Simi Valley â from VentureÃ±o <Simiyi>.
History Native Americans for Kids. The Native American Navajo tribe is one of the largest tribes of American Indians. They lived in the Southwest in areas that are today Arizona, New Mexico, Colorado, and Utah.The name Navajo comes from the Spanish who called them the Apaches of Navajo.They called themselves Dine or the People.hey lived in the Southwest in areas that are today Arizona, New Mexico, Colorado, and Utah. The name Navajo comes from the Spanish who called them the Apaches of Navajo. They called themselves Dine or the People.