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Losartan can be administered once or twice daily at total daily doses of 25 to 100 mg. If the antihypertensive effect measured at trough using once-aday dosing is inadequate, a twice-a-day regimen at the same total daily dose or an increase in dose may give a more satisfactory response.
If you think you, or someone you care for, might have accidentally taken more than the recommended dose of losartan or intentional overdose is suspected, contact your local hospital, GP or if in England call 111.