The Covington County, Alabama sales tax is 6.00% , consisting of 4.00% Alabama state sales tax and 2.00% Covington County local sales taxes.The local sales tax consists of a 2.00% county sales tax. The Covington County Sales Tax is collected by the merchant on all qualifying sales made within Covington County.
CASK-related intellectual disability, as its name suggests, is caused by mutations in the CASK gene. This gene provides instructions for making a protein called calcium/calmodulin-dependent serine protein kinase (CASK).
These mutations allow the CFTR protein to retain some of its function. Some affected males have a mild mutation in one copy of the CFTR gene in each cell and a more severe, cystic fibrosis-causing mutation in the other copy of the gene.Mutations in the CFTR gene disrupt the function of the chloride channel, preventing the usual flow of chloride ions and water into and out of cells.hese mutations allow the CFTR protein to retain some of its function. Some affected males have a mild mutation in one copy of the CFTR gene in each cell and a more severe, cystic fibrosis-causing mutation in the other copy of the gene.