The Covington County, Alabama sales tax is 6.00% , consisting of 4.00% Alabama state sales tax and 2.00% Covington County local sales taxes.The local sales tax consists of a 2.00% county sales tax. The Covington County Sales Tax is collected by the merchant on all qualifying sales made within Covington County.
CASK-related intellectual disability, as its name suggests, is caused by mutations in the CASK gene. This gene provides instructions for making a protein called calcium/calmodulin-dependent serine protein kinase (CASK).
Point Mutations. A point mutation is a single-letter swap -- an exchange of two bases (adenine to cytosine, for example) at a single location in the DNA molecule. Since the sequence of letters in a gene determines the sequence of amino acids in the protein it encodes, a point mutation can change the amino acid sequence of the resulting protein. Sometimes a change in the protein's amino acid sequence can have dramatic results. For example, sickle cell disease occurs when a single-point mutation in the gene that encodes the hemoglobin molecule results in deformed red blood cells.