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Navelbine is a chemotherapy medication for pleural mesothelioma that slows down the ability of mesothelioma cells to divide and spread. Navelbine (generic name: vinorelbine) is a relatively new chemotherapy drug on the mesothelioma scene.
Bendamustine is a white, water-soluble microcrystalline powder with amphoteric properties. It acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450.More than 95% of the drug is bound to protein-primarily albumin. Only free bendamustine is active. Elimination is biphasic with a half-life of 6â10 minutes and a terminal half-life of approximately 30 minutes.It is eliminated primarily through the kidneys.endamustine is a white, water-soluble microcrystalline powder with amphoteric properties. It acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450.