This thesaurus page is about all possible synonyms, equivalent, same meaning and similar words for the term bona fide. Princeton's WordNet(0.00 / 0 votes)Rate these synonyms: bona fide(adj) undertaken in good faith. Synonyms: bona fide, veritable, authentic, unquestionable. Antonyms: imitative, insincere, counterfeit.
Genetic Testing for ALS. Genetic Testing for ALS - ALS is directly hereditary in only 10 percent of families. The vast majority of ALS cases are sporadic, meaning that although there is likely a genetic predisposition involved, ALS is not directly inherited in a family. Although there is a genetic test for ALS, it is still quite limited. In 20 percent of families with inherited ALS, a change in the gene called SOD1 on chromosome 21 has been found, however, 80 percent of families with inherited ALS do not show a change in their SOD1 gene.
Sporadic and Familial ALS. Most cases of ALS are âsporadic,â meaning they are due to no known cause. Approximately 5-10% of cases are due to known genetic mutations. In most of those cases, another family member also has ALS or a related disease (see C9ORF72 below).9ORF72. This gene, discovered in 2011, is the most common genetic cause of ALS. (Its name refers to the position of an âopen reading frameâ on chromosome 9). Mutations in this gene account for between 25% and 40% of all familial ALS cases (depending on the population), and also approximately 4% to 6% of sporadic cases.