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How long does it take for an antibiotic to work? Well, it depends upon the type of antibiotic and how serious the infection is. Most antibiotics should work between 24-48 hours. Use the information in this article to decipher whether it is worth waiting or if you should call the doctor, nurse or pharmacist for input. Antibiotics directions and instructions.
1 73% - How long does it take for a rocephin shot to work for an ear infection? 2  44% - I had a rocephin shot yesterday for urinary infection.how long will it take to work? 3  53% - How soon should a rocephin shot along w/ a steroid shot work?evere ear infection in my child, MD only ordered 1 shot of Rocephin, how long does it take for this antibiotic to start relieving symptoms of ear infection.