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Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. Structure.
Medical and Recreational Uses: Zolpidem is a non-benzodiazepine hypnotic used in short-term treatment (up to 4 weeks) of insomnia. Zaleplon and zopiclone also are indicated for the treatment of insomnia. Potency, Purity and Dose: Recommended zolpidem dose is 10 mg immediately before bedtime (5 mg in the elderly).Recommended nighttime zaleplon and zopiclone doses are 5-20 mg and 7.5 mg, respectively.or zopiclone, a single 7.5 mg dose can cause severe residual effects on actual driving at 5 and 10 hours, severe residual effects on body sway and memory at 4 hours, and minor impairment of delayed free recall 9 hours after dosing.