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Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. Structure.
17 Reviews. Meclizine is the generic name for the prescription drug called Antivert and the over-the-counter (OTC) medicines known as Dramamine and Bonine. Meclizine is used to treat motion sickness and dizziness. The drug belongs to a class of drugs called antihistamines, which are generally used to treat allergies.However, meclizine works a little differently, reducing nausea and muscle spasms.eclizine is used to treat motion sickness and dizziness. The drug belongs to a class of drugs called antihistamines, which are generally used to treat allergies.