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Sclerotic breast cancer metastases in the pelvis. Bone metastases, or metastatic bone disease, is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare.
Definition of sclerotic. 1  1 : being or relating to the sclera. 2  2 : of, relating to, or affected with sclerosis.