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Sclerotic breast cancer metastases in the pelvis. Bone metastases, or metastatic bone disease, is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare.
The bone can either be destroyed (lytic process), or condense which is sclerotic. You can only speculate from the scan what it means. As the radiologist suggested, in most places sclerotic changes indicate a response to treatment, and body creating dense bone around the cancer.here is a sclerotic lesion with central bony destruction in the upper sacrum, noting slightly increased marginal sclerosis. There is increasing sclerosis within a lesion in L3 extending into the left pedicle from the left vertebral body, 2/36, 22 x 26 mm.