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How long does it take for an antibiotic to work? Well, it depends upon the type of antibiotic and how serious the infection is. Most antibiotics should work between 24-48 hours. Use the information in this article to decipher whether it is worth waiting or if you should call the doctor, nurse or pharmacist for input. Antibiotics directions and instructions.
Best Answer: antibiotics can start providing relief anywhere from 12 to 72 hours after you start taking them. Dental infections can be hard for the antibiotics to reach so its not uncommon to have wait a couple of days after starting the medication to see results.