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Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. Structure.
23 Reviews. 23 Reviews. Amitiza is the brand name for lubiprostone, a prescription drug used to relieve bloating and abdominal discomfort, improve stool texture, reduce the need to strain when you go to the bathroom, and decrease the feeling that you haven't completely relieved yourself.regnancy and Amitiza. If you are pregnant, planning a pregnancy or breastfeeding tell your doctor before taking Amitiza. Amitiza is in FDA Pregnancy Category C, meaning it there's some evidence it may harm a developing fetus and should only be taken when the benefits outweigh the risks.