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Sclerotic breast cancer metastases in the pelvis. Bone metastases, or metastatic bone disease, is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare.
Metastasis is involved in the vast majority of cancer-related deaths. In order to metastasize to a new site, a tumor requires a subset of conditions. Cancer cells must first break off from the primary tumor and pass through the area surrounding the lesion and into the blood vessel or lymphatic system.hese phases are loosely based on how far the cancer has spread from the original site. The spread of cancer to other types of the body is known as metastasis. When a cancer undergoes metastasis, it travels to other organs in the body.