Related Terms. 1  annual gross income. 2  exclusion ratio. 3  gift tax. 4  creditable coverage. 5  annual exclusion. 6  mutually exclusive investment decisions. 7  foreign housing exclusion. 8  mutual exclusion doctrine. 9  low exercise price option (LEPO). 10  foreign earned income exclusion.
Methaqualone was first synthesized in India in 1955 by scientists trying to find a cure for malaria. The drug was ineffective against the disease, but not as a central nervous system depressant â and if a user could resist its sedative effects, a user could get high.
[edit] Methadone maintenance has been used to treat opioid dependence for more than 45 years (invented in 1937). Therapeutic dosing is contingent upon individual patient needs, and the therapeutic dosage range is generally between 25 to 150 mg. Such a dose would not be tolerated by an opioid-naive individual.