Hoffmann's reflex. For the distal sign of nerve regeneration, see Hoffmann's sign. In medicine, Hoffmann's reflex, named after Johann Hoffmann, is a finding elicited by a reflex test which verifies the presence or absence of problems in the corticospinal tract.
Pinwheel was re-launched as Nickelodeon on April 1, 1979, and despite its prior history on the QUBE system under the Pinwheel name, Nickelodeon has declared that 1979 is the network's official launch year.
The series is based on a short produced for Nicktoons and Frederator Studios' animation incubator series Random! Cartoons. After the short became a viral hit on the Internet, Cartoon Network commissioned a full-length series that previewed on March 11, 2010, and officially premiered on April 5, 2010.