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How long does it take for an antibiotic to work? Well, it depends upon the type of antibiotic and how serious the infection is. Most antibiotics should work between 24-48 hours. Use the information in this article to decipher whether it is worth waiting or if you should call the doctor, nurse or pharmacist for input. Antibiotics directions and instructions.
It means it on this day the medicine starts to weaken the bacteria and it will another 4 days to really them. If no effect yet after taking the med. for 3 or more days, I think you can request the doctor to presecribe a higher dose and higher level of antibiotic. Nitrofurantoin (Macrodantin) is taken for 10 days.