The Covington County, Alabama sales tax is 6.00% , consisting of 4.00% Alabama state sales tax and 2.00% Covington County local sales taxes.The local sales tax consists of a 2.00% county sales tax. The Covington County Sales Tax is collected by the merchant on all qualifying sales made within Covington County.
CASK-related intellectual disability, as its name suggests, is caused by mutations in the CASK gene. This gene provides instructions for making a protein called calcium/calmodulin-dependent serine protein kinase (CASK).
1 Missense mutations or nonsynonymous mutations are types of point mutations where a single nucleotide is changed to cause substitution of a different amino acid. 2  This in turn can render the resulting protein nonfunctional. A nonsense mutation is a point mutation in a sequence of DNA that results in a premature stop codon, or a nonsense codon in the transcribed mRNA, and possibly a truncated, and often nonfunctional protein product.