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CCK plays a variety of roles in digestive processes, including inhibition of food intake, consistent with a role in satiety. In the lingual epithelium, the sensing of a broad spectrum of L-amino acids is accomplished by the heteromeric amino acid (umami) taste receptor (T1R1-T1R3).T1R1 and T1R3 subunits are also expressed in the intestine.A defining characteristic of umami sensing by T1R1-T1R3 is its potentiation by IMP or GMP.ensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion.
Zinc: Results from studies investigating the potential role of zinc in treating taste and smell disorders are contradictory. Well-designed research is needed to determine if zinc contributes to the treatment of taste and smell disorders.