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Sclerotic breast cancer metastases in the pelvis. Bone metastases, or metastatic bone disease, is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare.
Here a 44-year old male with a mixed lytic and sclerotic mass arising from the fifth metacarpal bone. There are calcified strands within the soft tissues. T2-weighted axial MR image demonstrates high signal intensity of the tumor in the metacarpal bone with extension of a lobulated soft tissue mass.hese lesions usually regress spontaneously and may then become sclerotic. Other benign lesions, like solitary bone cyst, fibrous dysplasia, chondroblastoma and other benign bone tumors may become inert and may also become sclerotic. The images show on the left a typical osteolytic NOF with a sharp sclerotic border.