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White blood cells known as lymphocytes arise from by mitosis of stem cells in the bone marrow. Some lymphocytes migrate to the thymus and become T cells that circulate in the blood and are associated with the lymph nodes and spleen.
Like the thymus, the spleen houses and aids in the maturation of immune system cells called lymphocytes. Lymphocytes are white blood cells that protect against foreign organisms that have managed to infect body cells. Lymphocytes also protect the body from itself by controlling cancerous cells. The spleen is valuable to the immune response against antigens in the blood.