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Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. Structure.
Xyzal is a brand of anti-histamine drug with the generic name of âlevocetirizineâ. It comes in tablets and oral solutions and is typically used to counter allergy-related symptoms. Xyzal is also considered a ânon-drowseâ anti-histamine since this drug does not have sedative effects. As the label âanti-histamineâ suggests, this drug opposes the action of histamine in the body. Histamine is said to be produced by the mast cells in the body in response to invasion by a foreign irritant or substance, commonly known as allergens.