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CCK plays a variety of roles in digestive processes, including inhibition of food intake, consistent with a role in satiety. In the lingual epithelium, the sensing of a broad spectrum of L-amino acids is accomplished by the heteromeric amino acid (umami) taste receptor (T1R1-T1R3).T1R1 and T1R3 subunits are also expressed in the intestine.A defining characteristic of umami sensing by T1R1-T1R3 is its potentiation by IMP or GMP.ensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion.
Itâs not your taste budsâ fault. Blame your stuffed-up nose. Seventy to seventy-five percent of what we perceive as taste actually comes from our sense of smell. Taste buds allow us to perceive only bitter, salty, sweet, and sour flavors. Itâs the odor molecules from food that give us most of our taste sensation.