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Hamilton considered Burr an unprincipled rogue. The antagonism between the two came to a head in 1804 when Hamilton thwarted Burr's attempt to gain re-nomination for Vice President as well as his bid to win the governorship of New York. Burr responded by challenging his antagonist to a duel, an invitation Hamilton felt compelled to accept.
In a duel held in Weehawken, New Jersey, Vice President Aaron Burr fatally shoots his long-time political antagonist Alexander Hamilton.Hamilton, a leading Federalist and the chief architect of Americaâs political economy, died the following day.hat happened next is agreed upon: Burr shot Hamilton in the stomach, and the bullet lodged next to his spine. Hamilton was taken back to New York, and he died the next afternoon. Few affairs of honor actually resulted in deaths, and the nation was outraged by the killing of a man as eminent as Alexander Hamilton.