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7 Hpw long would it take for (1) 81mg of aspirin to be completely out of your system...On for about 1 year. Dr. Venkata Chilakapati Dr. Chilakapati. Aspirin: For small dose of Aspirin elimination half life is 2 to 4.5 hours. So within 24 hours it will be completely eliminated from the body.
The logic is that taking an aspirin a day helps prevent heart attacks. Clinical data since the 1990s does show that a daily low dose of aspirin can help prevent a re-occurrence for people who have had a heart attack, stroke or disease of the heartâs blood vessels, the FDA says.