The Covington County, Alabama sales tax is 6.00% , consisting of 4.00% Alabama state sales tax and 2.00% Covington County local sales taxes.The local sales tax consists of a 2.00% county sales tax. The Covington County Sales Tax is collected by the merchant on all qualifying sales made within Covington County.
CASK-related intellectual disability, as its name suggests, is caused by mutations in the CASK gene. This gene provides instructions for making a protein called calcium/calmodulin-dependent serine protein kinase (CASK).
1 tk, a gene that encodes thymidine kinase, an enzyme that phosphorylates the nucleoside analog ganciclovir. 2  DNA polymerase fails to discriminate against the resulting nucleotide and inserts this nonfunctional nucleotide into freshly-replicating DNA. 3  So ganciclovir kills cells that contain the tk gene.f the replacement gene (A* in the diagram) is nonfunctional (a null allele), mating of the heterozygous transgenic mice will produce a strain of  knockout mice  homozygous for the nonfunctional gene (both copies of the gene at that locus have been knocked out).