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Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. Structure.
Asystole is sometimes referred to as a âflat line.â. Pulseless electrical activity (PEA) is a clinical condition characterized by unresponsiveness and no palpable pulse but with some organized cardiac electrical activity.Pulseless electrical activity has previously been referred to as electromechanical dissociation (EMD).With both asystole and PEA there is no blood flow to the brain unless immediate CPR is performed. When all emergency treatments are unsuccessful, death is confirmed.ulseless electrical activity has previously been referred to as electromechanical dissociation (EMD). With both asystole and PEA there is no blood flow to the brain unless immediate CPR is performed. When all emergency treatments are unsuccessful, death is confirmed.