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Sclerotic breast cancer metastases in the pelvis. Bone metastases, or metastatic bone disease, is a class of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare.
Definition of metastasis. plural. metastases. play \-ËsÄz\. 1a : change of position, state, or formb : the spread of a disease-producing agency (as cancer cells) from the initial or primary site of disease to another part of the body metastasis of breast cancer to bone â Medical Physics; also : the process by which such spreading occurs.