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Manganese is a part of many enzyme systems, including the enzymes involved in blood sugar control, energy metabolism, and thyroid hormone function. Manganese also participates in the antioxidant enzyme, superoxide dismutase, or SOD.
There is no specific evidence that manganese can prevent osteoporosis, but one study found that taking a combination of calcium, zinc, copper, and manganese helped lessen spinal bone loss in a group of post menopausal women. Anyone can develop osteoporosis, but it is common in older women.