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The drugâs initial approval noted mild side effects such as vomiting, itching, lethargy and diarrhea. Some 70 million doses of Trifexis have been distributed through 15,000 veterinary clinics, said Elanco spokeswoman Julie Lawless.
Medicine/Medical. immediate, temporary immunization against the effects of injection of a toxic extract owing to previous small injections of the same extract. 2. a decreased response to a medicine given over a period of time so that larger doses are required to produce the same response. . tachyphylaxis.