Hox gene is an example of a homeobox gene. The homeobox sequence codes for a 60 amino acid protein domain known as the homeodomain. The main role of homeodomain is to act as a switch that controls gene transcription.
(Histone modification hassome attributes of an epigenetic process, but the issue ofheritability has yet to be resolved.) This review concernsDNA methylation, focusing on the generation, inheri-tance, and biological significance of genomic methyl-ation patterns in the development of mammals.
DNA replication is the action of DNA polymerases synthesizing a DNA strand complementary to the original template strand. To synthesize DNA, the double-stranded DNA is unwound by DNA helicases ahead of polymerases, forming a replication fork containing two single-stranded templates.Replication processes permit the copying of a single DNA double helix into two DNA helices, which are divided into the daughter cells at mitosis.nitiation of eukaryotic DNA replication is the first stage of DNA synthesis where the DNA double helix is unwound and an initial priming event by DNA polymerase Î± occurs on the leading strand. The priming event on the lagging strand establishes a replication fork.