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Manganese is a part of many enzyme systems, including the enzymes involved in blood sugar control, energy metabolism, and thyroid hormone function. Manganese also participates in the antioxidant enzyme, superoxide dismutase, or SOD.
The structure and function of the mitochondria. are therefore particularly affected by manganese. status. Manganese activates enzymes associated. with fatty acid metabolism and protein. synthesis,3 and is involved in neurological. function.