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Aerobic bacteria require oxygen for cellular respiration, while anaerobic bacteria do not require oxygen and cannot grow in the presence of it. They produce energy through fermentation. They are similar in the the fact they can share nutritional requirements.
Key Difference â Aerobic vs Anaerobic Fermentation. The term Aerobic fermentation is a misnomer since fermentation is anaerobic, i.e., it does not require Oxygen. Thus, aerobic fermentation does not actually refer to a fermentation process; this process refers to the process of cellular respiration. The key difference between aerobic and anaerobic fermentation is that aerobic fermentation uses oxygen whereas anaerobic fermentation does not use oxygen.