Head and neck lymphedema can be caused by surgery or radiation therapy for tongue or throat cancer. It may also occur in the lower limbs or groin after surgery for colon, ovarian or uterine cancer, in which removal of lymph nodes or radiation therapy is required.
1 Heart attack. A heart attack can damage the area of the heart muscle that supports the mitral valve, affecting the function of the valve. If the damage is extensive enough, a heart attack can cause sudden and severe mitral valve regurgitation.  Abnormality of the heart muscle (cardiomyopathy).
Mitral valve regurgitation cause anemia - Could mitral valve regurgitation cause anemia? Unlikely. If one has mixed mitral valve disease with a heavily calcified mitral valve that is both stenotic and regurgitant, one could imagine marked turbulance of the blood flow across the mitral valve with destruction of rbc's however, this is very unlikely.