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Diabetic kidney disease, or diabetic nephropathy, is a complication of type 1 or type 2 diabetes caused by damage to the kidneys' delicate filtering system. Your kidneys contain millions of tiny blood vessel clusters (glomeruli) that filter waste from your blood.
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. Symptoms of high blood sugar include frequent urination, increased thirst, and increased hunger. If left untreated, diabetes can cause many complications. Type 2 DM begins with insulin resistance, a condition in which cells fail to respond to insulin properly. 2  As the disease progresses a lack of insulin may also develop. 3  This form was previously referred to as non insulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes.