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The system exerts its influence via release or inhibition of vasopressin (antidiuretic hormone, ADH) which acts on the kidney to decrease water excretion. Deficiency of ADH is usually due to hypothalamic-neurohypophyseal lesions (central diabetes insipidus) or insensitivity of the kidney to ADH (nephrogenic diabetes insipidus). These patients, if untreated, have the predictable result of dehydration, hyperosmolality, hypovolemia, and eventual death in severe cases.
Hypothyroidism and Vitamin D Deficiency. Itâs important to note that both thyroid hormone and Vitamin D bind to similar receptors known as steroid hormone receptors. A gene in the vitamin D receptor was demonstrated to predispose people to auto-immune thyroiditis, i.e. Hashimotoâs and Graveâs disease.itamin D deficiency may lead to some bone problems, related to hypothyroidism. There are two possible explanations on the hypothyroidism and vitamin D deficiency link: 1. The patient does not absorb vitamin D properly. 2.