No. The fact that a person who provides services is paid as an independent contractor, that is, without payroll deductions and with income reported by an IRS form 1099 rather than a W-2, is of no significance whatsoever in determining employment status.
Inherited metabolic disorders are a range of diseases caused by defective genes. Though rare, they can have devastating consequences for patients and their families. Research by the pharmaceutical industry has led to many specialised treatments.n the human body, the urea cycle is the metabolic pathway allowing the transformation of ammonia into urea. In children with N-acetylglutamate synthetase (NAGS) deï¬ciency, the disorder leads to a build up of ammonia in the blood which can cause irreversible brain damage or death.
But the mutations we hear about most often are the ones that cause disease. Some well-known inherited genetic disorders include cystic fibrosis, sickle cell anemia, Tay-Sachs disease, phenylketonuria and color-blindness, among many others. All of these disorders are caused by the mutation of a single gene. Most inherited genetic diseases are recessive, which means that a person must inherit two copies of the mutated gene to inherit a disorder.