Most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. Often this leads to an irregular heartbeat-called an arrhythmia-that causes a severe decrease in the pumping function of the heart.
The abnormal FIG-ROS fusion protein has constitutively active kinase activity that causes oncogenic transformation (a transformation from normal cells to cancer cells). Chromosomal inversion s: reversing the orientation of a chromosomal segment.
Lesson Summary. In summary, transformation is the process in which the genetic makeup of a cell is changed by introduction of DNA from the surrounding environment. To make bacterial cells competent for transformation, the cells are incubated in chilled calcium chloride.esson Summary. In summary, transformation is the process in which the genetic makeup of a cell is changed by introduction of DNA from the surrounding environment. To make bacterial cells competent for transformation, the cells are incubated in chilled calcium chloride.