28598 County Road 4, Pequot Lakes, MN 56472 View this property at 28598 County Road 4, Pequot Lakes, MN 56472
CRISPR/Cas9, a gene-editing technique that can target and modify DNA with groundbreaking accuracy, is both the newest darling and the newest villain of genetics research.Invented in 2012 by scientists at the University of California, Berkeley, CRISPR/Cas9 has received a lot of attention this year.f scientists are able to nail down the use of CRISPR/Cas9 in human germ cells, thereâs no question that it could confer major benefits. Namely, the technology could eradicate hereditary diseases such as cystic fibrosis, sickle-cell anemia, and Huntingtonâs disease from a family line altogether.
A: CRISPR âspacerâ sequences are transcribed into short RNA sequences (âCRISPR RNAsâ or âcrRNAâ) capable of guiding the system to matching sequences of DNA. When the target DNA is found, Cas9 â one of the enzymes produced by the CRISPR system â binds to the DNA and cuts it, shutting the targeted gene off. Using modified versions of Cas9, researchers can activate gene expression instead of cutting the DNA. These techniques allow researchers to study the geneâs function.