Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats (see PRECAUTIONS). Spironolactone should be used only in those conditions described under INDICATIONS AND USAGE. Unnecessary use of this drug should be avoided.
The density of a population can be regulated by various factors, including biotic and abiotic factors and population size. Density-dependent regulation can be affected by factors that affect birth and death rates such as competition and predation.
Nutrition's Influence on Physical Development. A number of other factorsâso-called environmental influencesâcan affect physical development as well. Nutrition is important to normal growth processes. Parents should make an effort to ensure their child conÂ­sumes a well-balanced diet.erhaps more than any other factor, your child's growth and ultimate height will be influenced by heredity. While there are exceptions, tall parents usually have tall children, and short parents usually have short children. Those are the realities of genetics.