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The sciatic nerve is the largest single nerve in the human body; it runs from each side of the lower spine through deep in the buttock into the back of the thigh and all the way down to the foot. It serves a vital role in connecting the spinal cord with the leg and foot muscles.
Where is sciatic nerve pain felt? Sciatic nerve pain can be felt anywhere along the path of the sciatic nerve, which spans from the lower spine through the hips, buttocks, legs and feet. Because this important nerve transmits motor and sensory signals throughout the lower body, interference with the sciatic nerve can be debilitating.