Multidrug-resistant tuberculosis (MDR-TB) is defined as TB that is resistant to both isoniazid [INH] and rifampicin [RMP], two of the first-line drugs used in treating smear-positive pulmonary tuberculosis.ultidrug-Resistant TB (MDR-TB). Extensively drug-resistant tuberculosis (XDR-TB) is defined by the WHO as MDR-TB with additional resistance to any fluoroquinolone (FQ) and to at least one of three injectable second-line anti-tuberculosis drugs used in treatment (capreomycin [CPM], kanamycin [KM] or amikacin [AMK]).
Wither, shrivel imply a shrinking, wilting, and wrinkling. Wither (of plants and flowers) is to dry up, shrink, wilt, fade, whether as a natural process or as the result of exposure to excessive heat or drought: Plants withered in the hot sun. Shrivel, used of thin, flat objects and substances, such as leaves, the skin, etc., means to curl, roll up, become wrinkled: The leaves shrivel in cold weather.
noun. verb. The definition of a hobble is an awkward way of walking usually caused by restraint or injury, or a rope or shackle used to hold an animal's feet to keep the animal from walking.obble is defined as to limp. walk or speak in an awkward way, or to cause some other person or animal to have trouble moving forward or walking. 1  When you break your leg and you have to walk around with crutches and a full cast, this is an example of a time when you hobble.