1 Stair Treads and Risers should be pre-cut side to side and front to back before spreading any adhesive. 2  Abrasive Strips should be cut 1â16 shorter than the overall length of the Stair Tread. 3  Make sure Stair Treads will slide onto and off of step before applying adhesive. 4  Do not force Treads in at ends-cut loosely.
Rating Newest Oldest. Best Answer: Topamax (topiramate) is an antiepileptic (AED) and anti-migraine drug that is well known to cause weight loss in some patients. Typically weight loss is minimal and it is heavily dose dependent (ie a larger dose causes more weight loss and anorexia (loss of appetite)).
Since the brains dopamine and norepinephrine systems are closely linked, the ability of topiramate to reduce increases in both neurotransmitters suggests that this drug has potential for treating nicotine abuse, Schiffer said. Topiramate did not significantly modulate the effect of nicotine on serotonin, however. In fact, serotonin was the only neurotransmitter affected by topiramate alone, showing a slight increase.