The placenta is a fetomaternal organ. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell.
A patient who misses a dose of BRILINTA should take one tablet (the next dose) at its scheduled time 1 BRILINTA is metabolized by the liver and impaired hepatic function can increase risks for bleeding and other adverse events.
The usual initial dosage is 150 mg bd or 300 mg nocte. This may be increased to ranitidine 300 mg twice daily without an increased incidence of unwanted effects. Subsequently a maintenance dose of 150 mg nocte may be used.