A non-reactive result indicates lack of specific immune response to Hepatitis B surface antigen or vaccine. Such individuals are presumed to be non-immune and therefore su â¦ sceptible to Hepatitis B infection.
Symptoms of Hip Dysplasia in German Shepherds. difficulty rising or climbing inclines ; hip soreness ; limping ; muscle atrophy on the rump ; German Shepherd hip dysplasia signs may become evident between 5 and 8 months. But, some dogs will not show any signs until they are mature adults. Other canine hip dysplasia symptoms: A young dog may run with its back legs in sync, almost like a bunny hop. Decreased range of motion may be noticed as the pup will be unable to extend their leg backward very far. The pup will hesitate to jump and will not want to stand up on its rear legs.
Birth Control for Dogs. When does a female dog first come into \heat?\. Puberty, or sexual maturity, in the female dog usually occurs around six months of age. The smaller breeds tend to go into estrus, or heat, earlier, and some females can have their first heat cycle as early as four months of age.