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The Plague of Justinian (AD 541â542) was a pandemic that afflicted the Eastern Roman Empire, including its capital Constantinople. At its peak, 5,000 people per day in Constantinople died from it, killing half the population. From there, the plague moved east and west, becoming antiquity's most lethal known pandemic.
The bacterium legionella causes Legionnaires' disease, a lung infection which is a severe form of pneumonia. The disease spreads by inhaling the bacteria or through contact with a person suffering from the disease. Legionella also cause a flu-like illness called Pontiac fever.Yaws disease is a relatively lesser known disease caused by the bacteria Treponema pertenue. It affects the skin, bones, and cartilage, and spreads through skin contact.uberculosis is an infectious disease. The bacteria that cause tuberculosis are called mycobacterium tuberculosis. People with TB or tuberculosis cough excessively and suffer a terrible pain in the chest. They cough up blood and display excessive weight loss, fatigue, loss of appetite, and persistent fever.