Not as wet today; hot with a 'feels like' temperature up to 100. The weather across South Florida should be drier than earlier in the week, but it will also be hot. According to the National Weather Service, it will be partly sunny on Thursday with a high near 88 but a heat index that will make it feel close to 100. Winds will be light and out of the east. ... Weather.
Glial cell line-derived neurotrophic factor (GDNF) is a secretory protein that is widely expressed in the CNS and peripheral tissues. It is synthesized in the form of precursor pre-pro-GDNF that is proteolytically cleaved to mature, biologically active neurotrophic factor (Lin et al., 1993).
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Epidermal growth factor receptor mutation is associated with response to therapy in resected advanced non-small-cell lung cancer. 2  Nuclear EGFR protein expression predicts poor survival in early stage non-small cell lung cancer. 3  EGFR activating mutations are associated with brain metastases in non-small lung cancer.