HIT predisposes to thrombosis, the abnormal formation of blood clots inside a blood vessel, and when thrombosis is identified the condition is called heparin-induced thrombocytopenia and thrombosis (HITT).
When and where was the fork invented ? Helen Brown, Auckland New Zealand According to the very entertaining book Ancient Inventions by Peter James and Nick Thorpe, the fork was probably invented in the Eastern Roman Empire of Byzantium where forks were first used during the 4th century AD.
Eleven years later, James Bogardus patented a âforever pointedâ pencil in the U.S. While these patents mark a great step forward in pencil history, the giant leap wouldnât occur until 1879. This is when Joseph Hoffmann invented the pushbutton clutch in New York City. First incorporated into the Eagle Automatic, a product of the Eagle Pencil Company, this represents the first true mechanical pencil.