Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats (see PRECAUTIONS). Spironolactone should be used only in those conditions described under INDICATIONS AND USAGE. Unnecessary use of this drug should be avoided.
The density of a population can be regulated by various factors, including biotic and abiotic factors and population size. Density-dependent regulation can be affected by factors that affect birth and death rates such as competition and predation.
Many factors influence the ability of deer populations to successfully reproduce and maintain a constant population over time. Some of these include: disease, predator/prey relationships, habitat destruction and degradation, food availability, hunting pressure, and weather conditions.