ICH overview. 1  Guidelines for the investigator. 2  Guidelines for the trial sponsor (industrial, academic) 3  Guidelines for the clinical trial protocol and protocol amendments. 4  Guidelines for the Investigator's brochure.
A mark or sign made by an individual on an instrument or document to signify knowledge, approval, acceptance, or obligation. The term signature is generally understood to mean the signing of a written document with one's own hand. However, it is not critical that a signature actually be written by hand for it to be legally valid. It may, for example, be typewritten, engraved, or stamped.
vs. Check Point UTM-1. A signature file is a short text file you create for use as a standard appendage at the end of your e-mail notes or Usenet messages. For example, you might include your full name, occupation or position, phone number, fax number, e-mail address, and the address of your Web site if you have one.heck Point UTM-1. A signature file is a short text file you create for use as a standard appendage at the end of your e-mail notes or Usenet messages. For example, you might include your full name, occupation or position, phone number, fax number, e-mail address, and the address of your Web site if you have one.