ICH overview. 1  Guidelines for the investigator. 2  Guidelines for the trial sponsor (industrial, academic) 3  Guidelines for the clinical trial protocol and protocol amendments. 4  Guidelines for the Investigator's brochure.
A mark or sign made by an individual on an instrument or document to signify knowledge, approval, acceptance, or obligation. The term signature is generally understood to mean the signing of a written document with one's own hand. However, it is not critical that a signature actually be written by hand for it to be legally valid. It may, for example, be typewritten, engraved, or stamped.
Signature Health is... Dedicated to providing accessible, comprehensive recovery services to people experiencing mental health and/or substance abuse problems. We work with adults, adolescents, children and families, offering much needed help in a supportive, respectful environment. Our staff is highly trained, experienced and professional, entirely committed to providing effective care to every single client.