Sorry to be a buzzkill, but there is no definitive answer to who-is-the-most-reactive-element-amongst-all, because it takes two to tango. One could ask which element is the most reactive with Sodium? The answer then is Fluorine, not Caesium. Or, perhaps you want to know which element is the most reactive with Nitrogen. Its Lithium! Shocker!
1 Day 1: reduce dosage of amitriptyline to 75 mg/day. 2  Day 8: reduce dosage of amitriptyline to 50 mg/day. 3  Day 15: reduce dosage of amitriptyline to 25 mg/day. 4  Day 22: reduce dosage of amitriptyline to 10 mg/day. Day 8: reduce dosage of amitriptyline to 50 mg/day. 2  Day 15: reduce dosage of amitriptyline to 25 mg/day. 3  Day 22: reduce dosage of amitriptyline to 10 mg/day. 4  Day 29: stop administration of amitriptyline.
The T1/2 alpha and T1/2 beta for amitriptyline were 1.5 - 3.1 and 15 - 43 h respectively. The rate of elimination of amitriptyline was not dose-dependent. The arteriovenous differences in the total amitriptyline+nortriptyline concentration were maximal in patients admitted soon after intake of drugs.Amitriptyline concentrations in cerebrospinal fluid were quantitatively similar to the unbound amitriptyline concentration in blood.he rate of elimination of amitriptyline was not dose-dependent. The arteriovenous differences in the total amitriptyline+nortriptyline concentration were maximal in patients admitted soon after intake of drugs.