Medical Definition of Immunoglobulin E. Immunoglobulin E: A class of immunoglobulins that includes the antibodies that are important in an allergic response. Abbreviated IgE. A person who has an allergy often has elevated blood levels of IgE. IgE antibodies attack and engage the invading army of allergens.
Liver failure occurs when large parts of the liver become damaged beyond repair and the liver is no longer able to function. Liver failure is a life-threatening condition that demands urgent medical care. Most often, liver failure occurs gradually and over many years.
Researchers have noted that exhaustion and fatigue are the single most common symptom of liver damage, and it typically has a significant and damaging impact on the patientâs quality of life. Unfortunately, the specific causes of liver disease-related fatigue and exhaustion are not fully understood. Researchers speculate that the root cause of liver disease-related chronic fatigue may be caused by changes in brain chemistry and hormone levels which result from impaired liver function. In particular, altered levels of corticotropins, serotonin, and noradrenaline may be at the root of depleted energy levels.