Fair Labor Standards Act - FLSA. A maintenance worker is hired to work 35 hours at $15/hr. At $525/week, he passes the salary test (his income is greater than $455/week) but, as he cannot exercise discretion or independent judgment and is directly supervised, he is classified as a non-exempt employee.
Although Hox genes contain and are originally named because of the homeobox sequence, not all homeobox-containing genes are Hox genes (other examples include the POU genes and CDX genes). The homeobox encodes for a protein sequence called the homeodomain, which is a DNA-binding domain.
Gene Therapies for Tay-Sachs. The HEXA gene is a protein encoding gene that codes for the lysosomal enzyme beta-hexosaminidase. This enzyme, combined with the GM2 activator protein, is responsible for the breakdown of ganglioside GM2 within the lysosome. Defects in the HEXA gene, however, prevent this degradation, leading to a buildup of toxins in brain and spinal cord cells.