Bipolar disorder is primarily a biological disorder that occurs in a specific area of the brain and is due to the dysfunction of certain neurotransmitters, or chemical messengers, in the brain. These chemicals may involve neurotransmitters like norepinephrine, serotonin and probably many others.
The blood transfusion will start slowly so healthcare providers can watch for signs of a reaction. Even a small amount of donor blood can cause a reaction. A healthcare provider will stay with you for at least 15 minutes after the transfusion starts. Healthcare providers will check your vital signs at least once every hour. Tell them if you have signs of a reaction, such as pain, nausea, or itching.
Delayed hemolytic reactions occur more than 24 hours after a transfusion, and occur more frequently (1 in 20,569 blood components transfused in the USA in 2011). They are due to the same mechanism as in acute hemolytic reactions.