Symptoms of sciatica originating at this level of the lower back may include: pain and/or numbness at the top of the foot, particularly in the web between the great toe (big toe) and the second toe. 1  See All about the L4-L5 Spinal Segment. 2  Sciatica from S1 nerve root.
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An institutional review board, also known as an independent ethics committee, ethical review board, or research ethics board, is a type of committee that applies research ethics by reviewing the methods proposed for research to ensure that they are ethical. Such boards are formally designated to approve, monitor, and review biomedical and behavioral research involving humans. They often conduct some form of risk-benefit analysis in an attempt to determine whether or not research should be comple