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Cholecystokinin definition, a hormone secreted by the upper portion of the intestine that stimulates contraction of the gallbladder and increases secretion of pancreatic juice. See more. Dictionary.com
A polypeptide hormone produced principally by the small intestine in response to the presence of fats, causing contraction of the gallbladder, release of bile, and secretion of pancreatic digestive enzymes.Also called pancreozymin. gastrointestinal hormone liberated from the intestinal mucosa in response to arrival of the products of digestion from the stomach. It stimulates secretion of pancreatic enzymes and gallbladder contraction. Abbreviated CCK, CCK-PZ. Called also cholecystokinin-pancreozymin, pancreozymin.