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Test Overview. An estrogen test measures the level of the most important estrogen hormones in a blood or urine sample. It measures estradiol, estriol, and estrone. Estradiol is the most common type of estrogen measured for nonpregnant women. The amount of estradiol in a woman's blood varies throughout her menstrual cycle.
Low levels of estradiol, a form of estrogen, can indicate that your ovaries are starting to fail. When estradiol levels are below 30, it may signal that you are in menopause. However, the most important test used to diagnose premature menopause is a blood test that measures follicle stimulating hormone (FSH). FSH causes your ovaries to produce estrogen. When your ovaries slow down their production of estrogen, your levels of FSH increase. When your FSH levels rise above 40 mIU/mL, it usually indicates that you are in menopause.