28598 County Road 4, Pequot Lakes, MN 56472 View this property at 28598 County Road 4, Pequot Lakes, MN 56472
CRISPR/Cas9, a gene-editing technique that can target and modify DNA with groundbreaking accuracy, is both the newest darling and the newest villain of genetics research.Invented in 2012 by scientists at the University of California, Berkeley, CRISPR/Cas9 has received a lot of attention this year.f scientists are able to nail down the use of CRISPR/Cas9 in human germ cells, thereâs no question that it could confer major benefits. Namely, the technology could eradicate hereditary diseases such as cystic fibrosis, sickle-cell anemia, and Huntingtonâs disease from a family line altogether.
The type II CRISPR mechanism is unique compared to other CRISPR systems, as only one Cas protein (Cas9) is required for gene silencing (12). In type II systems, Cas9 participates in the processing of crRNAs (12), and is responsible for the destruction of the target DNA (11).his contrasts with other genome editing tools, including zinc finger and TALENs, where redesign of the protein-DNA interface is required. Furthermore, CRISPR/Cas9 enables rapid genome-wide interrogation of gene function by generating large gRNA libraries (51, 53) for genomic screening.