Clorox's answer: Itâs easy to refill the new Smart TubeÂ® spray bottle. Simply twist the trigger on the spray bottle counterclockwise and pull upward to remove the trigger head. Refill the spray bottle. Then, to replace trigger, align the red-tipped tube on the trigger over tub opening inside of the bottle.
Symptoms of botulism The time it takes to develop symptoms can vary from a few hours to several days after exposure to the Clostridium botulinum bacteria or their toxins. Depending on the exact type of the condition (see Causes and types of botulism below), some people initially have symptoms such as feeling sick, vomiting, stomach cramps, diarrhoea or constipation.
Clostridium contains around 100 species that include common free-living bacteria, as well as important pathogens. The five main species responsible for disease in humans are: 1  C. botulinum can produce botulinum toxin in food or wounds and can cause botulism. C. botulinum can produce botulinum toxin in food or wounds and can cause botulism. 2  Honey sometimes contains spores of C. botulinum, which may cause infant botulism in humans one year old and younger. 3  The toxin eventually paralyzes the infant's breathing muscles.