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On average sciatica affects adults between the age range of 30 to 50 years, and this is the population most likely to chalk their pain up to age and muscle deterioration and are less likely to seek medical help right away.
1 Sciatica is nerve pain from irritation of the sciatic nerve. 2  The sciatic nerve is the largest nerve in the body. 3  Sciatica pain is typically felt from the low back to behind the thigh and radiating down below the knee. 4  Treatments for sciatica depend on the underlying cause and the severity of the pain.ciatica facts. 1  Sciatica is nerve pain from irritation of the sciatic nerve. 2  The sciatic nerve is the largest nerve in the body. 3  Sciatica pain is typically felt from the low back to behind the thigh and radiating down below the knee. 4  Treatments for sciatica depend on the underlying cause and the severity of the pain.