Most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. Often this leads to an irregular heartbeat-called an arrhythmia-that causes a severe decrease in the pumping function of the heart.
The abnormal FIG-ROS fusion protein has constitutively active kinase activity that causes oncogenic transformation (a transformation from normal cells to cancer cells). Chromosomal inversion s: reversing the orientation of a chromosomal segment.
Teratogen, Teratogenic, Teratogenicity. A teratogen is a substance which can cause birth defects. Teratogenic means able to cause birth defects. Teratogenicity is the ability of a chemical to cause birth defects. Teratogenicity results from a harmful effect to the embryo or the fetus/foetus.