As a publication, OPCS-4 is split into two volumes; a tabular list (Volume I) and an alphabetical index (Volume II). An electronic version is also available. However, a number of supplementary publications are also used by coding staff.
The prize was claimed in 1864 by Louis Pasteur, as he published the results of an experiment he did to disproved spontaneous generation in these microscopic organisms. 1  Observation(s): From Needham s and Spallanzani s experiments, it was known that soup that was exposed to the air spoiled bacteria grew in it.
However, when Spallanzani heard of this experiment, he did not believe it. Spallanzani proposed that the microorganisms could have entered the flask after it was boiled, and before it was sealed. In order to test Needham's theory, Spallanzani put broth in a flask, sealed the flask so that way no air could get in, and boiled it.