A non-reactive result indicates lack of specific immune response to Hepatitis B surface antigen or vaccine. Such individuals are presumed to be non-immune and therefore su â¦ sceptible to Hepatitis B infection.
Symptoms of Hip Dysplasia in German Shepherds. difficulty rising or climbing inclines ; hip soreness ; limping ; muscle atrophy on the rump ; German Shepherd hip dysplasia signs may become evident between 5 and 8 months. But, some dogs will not show any signs until they are mature adults. Other canine hip dysplasia symptoms: A young dog may run with its back legs in sync, almost like a bunny hop. Decreased range of motion may be noticed as the pup will be unable to extend their leg backward very far. The pup will hesitate to jump and will not want to stand up on its rear legs.
First estrus generally occurs when an unspayed female dog is between six and 24 months old. It tends to occur earlier for small-breed dogs and later for large-breed dogs. Although it varies with different breeds and individual dogs, an unspayed female usually goes into heat twice yearly, about every six months. The time during which male dogs are attracted to a female dog is variable, approximately 18 days. However, females are receptive to males for only about half of this time. During estrus, your female dog may appear nervous, easily distracted and more alert than usual.