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On average sciatica affects adults between the age range of 30 to 50 years, and this is the population most likely to chalk their pain up to age and muscle deterioration and are less likely to seek medical help right away.
Other causes of sciatica include: 1  Lumbar spinal stenosis-a narrowing of the spinal cord (a channel within the vertebrae that contains the nerves) in the lower back that may compress the sciatic nerve. 2  Spondylolisthesis-a condition in which a disc may slip forward over the vertebra below it, pinching the sciatic nerve.ften, the term sciatica is confused with general back pain. However, sciatica is not just limited to the back. The sciatic nerve is the longest and widest nerve in the human body. It runs from the lower back, through the buttocks, and down the legs, ending just below the knee.