ICH overview. 1  Guidelines for the investigator. 2  Guidelines for the trial sponsor (industrial, academic) 3  Guidelines for the clinical trial protocol and protocol amendments. 4  Guidelines for the Investigator's brochure.
A mark or sign made by an individual on an instrument or document to signify knowledge, approval, acceptance, or obligation. The term signature is generally understood to mean the signing of a written document with one's own hand. However, it is not critical that a signature actually be written by hand for it to be legally valid. It may, for example, be typewritten, engraved, or stamped.
Signatures. Signatures are blocks of text that are automatically appended to every message that you send (including both new messages and replies to incoming messages). They are generally used to provide additional contact information, legal terms or some other boilerplate information that is relevant to every email.ignatures. Signatures are blocks of text that are automatically appended to every message that you send (including both new messages and replies to incoming messages). They are generally used to provide additional contact information, legal terms or some other boilerplate information that is relevant to every email.