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1 Use common sense: If it upsets your stomach when you eat it, avoid it. Everyone is different, but spicy foods, citrus fruits, and fatty foods are common irritants.  Stop smoking. Heavy smokers are more likely to develop duodenal ulcers than nonsmokers.
7 Foods to Prevent Ulcers. Before you reach for a glass of milk to soothe your ulcer pain, consider this: Much of what we used to know about ulcers has been proven wrong. Most ulcers aren't caused directly by stress but by the bacterium Helicobacter pylori, which is why ulcers today are often treated with antibiotics along with an acid suppressor. Find out which foods can aid in healing and preventing ulcers.