Multidrug-resistant tuberculosis (MDR-TB) is defined as TB that is resistant to both isoniazid [INH] and rifampicin [RMP], two of the first-line drugs used in treating smear-positive pulmonary tuberculosis.ultidrug-Resistant TB (MDR-TB). Extensively drug-resistant tuberculosis (XDR-TB) is defined by the WHO as MDR-TB with additional resistance to any fluoroquinolone (FQ) and to at least one of three injectable second-line anti-tuberculosis drugs used in treatment (capreomycin [CPM], kanamycin [KM] or amikacin [AMK]).
Wither, shrivel imply a shrinking, wilting, and wrinkling. Wither (of plants and flowers) is to dry up, shrink, wilt, fade, whether as a natural process or as the result of exposure to excessive heat or drought: Plants withered in the hot sun. Shrivel, used of thin, flat objects and substances, such as leaves, the skin, etc., means to curl, roll up, become wrinkled: The leaves shrivel in cold weather.
verb (used with object), hewed, hewed or hewn, hewing. 1. to strike forcibly with an ax, sword, or other cutting instrument; chop; hack. 2. to make, shape, smooth, etc., with cutting blows: to hew a passage through the crowd; to hew a statue from marble. 3. to sever (a part) from a whole by means of cutting blows (usually followed by away, off, out, from, etc.):