Most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. Often this leads to an irregular heartbeat-called an arrhythmia-that causes a severe decrease in the pumping function of the heart.
The abnormal FIG-ROS fusion protein has constitutively active kinase activity that causes oncogenic transformation (a transformation from normal cells to cancer cells). Chromosomal inversion s: reversing the orientation of a chromosomal segment.
A transformation is a dramatic change in form or appearance. An important event like getting your driverâs license, going to college, or getting married can cause a transformation in your life. A transformation is an extreme, radical change. A simple haircut won't cause a transformation in your appearance, but if you dyed your hair purple and got a tattoo across your forehead, that would be another story.