Science vs Common Sense. Saxophones are mostly made from brass, which is an alloy mostly of copper and zinc. There are and have been slightly different combinations, and various other metals (e.g. lead) also included. Saxophones are also made from other materials, e.g. copper, bronze, silver and plastic. Various finishes are available: different types of lacquer and metal plating, e.g. silver, gold and nickel.
Due to the many other functions of melanocyte-stimulating hormone besides melanin production, there are likely to be a number of other factors that regulate its production. This means that, unlike most hormones, melanocyte-stimulating hormone release is not thought to be controlled by a direct feedback mechanism.
Melanin is produced by special cells called melanocytes. More melanin is produced when the skin is not exposed to sunlight. Melanin ranges in color from yellow to brown to black. The stratum basale cells phagocytize the melanin produced by the melanocytes and it accumulates within them. Freckles and moles are seen where melanin is concentrated in one spot.