As folate is vital in the first trimester of pregnancy for healthy fetal development, the use of antifolates is strongly contraindicated in pregnancy and carries significant teratogenic risk. Low doses of methotrexate can deplete folate stores and cause side-effects that are similar to folate deficiency.
Cause of Adult Mumps. Adult mumps is caused by an infection with the mumps virus, which is found worldwide. The mumps virus is an RNA (ribonucleic acid) virus from the family Paramyxovirus of the genus Rubulavirus. The mumps virus only infects humans.
Growth hormone deficiency in adults is rare and may be caused by pituitary adenoma â a tumor on the pituitary gland â or treatment of the adenoma with surgery or radiotherapy. For adults who have a growth hormone deficiency, injections of human growth hormone can: 1  Increase exercise capacity. 2  Increase bone density.