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Antibiotics will stay in your system fro 7 to 10 days.... Antibiotics will stay in your system fro 7 to 10 days. The actual time will depend upon the type of antibiotic taken, the dosage of the antibiotic taken and individual human body as well. Some antibiotics may stay for shorter durations than this also. jack perry.
It will stay in your body for over a week. If you have taken only one dosage, then diflucan will stay in your system for about 30 hours to three to four days. It is difficult to state the exact time period, but that is how long it might take infection to clear up with a single dose if the infection is mild.