According to the U.S. Census Bureau, the county has a total area of 685 square miles (1,770 km2), of which 681 square miles (1,760 km2) is land and 3.8 square miles (9.8 km2) (0.6%) is water. It is the fourth-largest county in Tennessee by area. The county is located atop the Cumberland Plateau.
Revenue passenger kilometres (RPK) is a measure of the volume of passengers carried by an airline. A revenue passenger-kilometre is flown when a revenue passenger is carried one kilometre. A passenger for whose transportation an air carrier receives commercial remuneration is called a revenue passenger.
Creatine kinase (CK) â also known as creatine phosphokinase (CPK) or phospho-creatine kinase â is an enzyme (EC 2.7.3.2) expressed by various tissues and cell types.CK catalyses the conversion of creatine and utilizes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP).hus creatine kinase is an important enzyme in such tissues. Clinically, creatine kinase is assayed in blood tests as a marker of damage of CK-rich tissue such as in myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular dystrophy, the autoimmune myositides and in acute renal failure.