In enzymes, some of these amino acids form a site in the structure that catalyzes the enzymatic reaction. This site, called the active site of the enzyme, has amino acids that bind specifically to the substrate molecule, also called a ligand (Fig. 2). In a similar manner, certain sites in cell receptor proteins bind to specific ligand molecules that the receptor recognizes.
When did France's second empire end? The Second Empire ended with the swift and catastrophic defeat of  France in the Franco-Prussian war of 1870. The war was engineered  by Bismarck with the idea that Germany â¦would be united.This  included the capture by the Prussians of the Napoleon III. Then the  proclamation at Versailles of the German Empire, the loss to France  of Alsace and Lorraine, and the proclamation of the Third Republic.
The Republic. By the time the Second Punic War had ended, Carthage was a mere shadow of its former power. However, Hannibal proved to be as good a governor as he was as a general, and soon Carthage recovered. However, Masinissa, governor of Numidia and a strong ally of the Romans, was able to pick at Carthage until Carthage attacked Numidia in 150 BC, breaking the treaty that ended the Second War.