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The following causes of Eosinophilia are diseases or conditions that affect more than 1 million people in the USA: 1  Connective tissue disease. 2  Food allergy. 3  Psoriasis. 4  Systemic lupus erythematosus. 5  more causes...Â».
Eosinophilic granulocytes are mostly located in tissues, and not in the peripheral blood. They are produced in the bone marrow. Before moving to tissues they remain in the peripheral blood for about 10 hours. Eosinophilia accompanies immune and allergic reactions. Eosinophilic granulocytes have antihistaminic function, so by eliminating histamine they prevent its activities available for producing edema and smooth muscles spasm. They have power of phagocytosis, but in that ability they are far behind neutrophilis.