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The dosage of Benadryl for dogs is 1 mg/lb given every 8 hours (three times a day). For example, a dog weighing 40 lbs would need 40 mg of Benadryl per dose. Benadryl, or diphenhydramine, is commonly prescribed by vets when a dog is suffering from allergies, or as a preventative measure for motion sickness if youâre planning on travelling with your pet.
The dosage instructions for Benadryl are one 25mg tablet per 25 pounds in body weight, so a dog weighing 50 pounds would require two tablets. There are several ways you can try giving your dog a Benadryl tablet: â¢ Crush the tablet up in some moist food.