Metastatic bone disease is a serious condition in which cancer has migrated from another part of the body, such as the lung, breast, prostate, thyroid, or kidney into one or more bones of the skeleton. Metastatic bone disease is not the same as cancer that originates in the bone, such as sarcoma.
In this article. Dupuytrenâs contracture, also known as Dupuytrenâs disease, is a hand deformity that causes the tissue beneath the surface of the hand to thicken and contract. Evidence of Dupuytrenâs usually begins with a thickening of the palm.
By Mayo Clinic Staff. A number of factors are believed to increase your risk of the disease, including: 1  Age. Dupuytren's contracture occurs most commonly after the age of 50. 2  Sex. Men are more likely to develop Dupuytren's and to have more severe contractures than are women.  Ancestry.