Secondly, applied research, which is the application of basic research to understanding how behaviour can be changed in everyday setting. When applied research is conducted using samples that are representative of the population to demonstrate effective behaviour change it is particularly relevant to policy makers.
Making the world better, one answer at a time. During skeletal muscle contraction calcium ions expose myosin binding sites on to the actin. When a nerve sends a signal to a muscle to do some action the release of acetylcholine at the neuromuscular junction triggers calcium to be released into the cytoplasm. At rest, the cell has a low concentration of calcium.
1 Thin filaments in smooth muscle do not contain troponin. 2  calcium does not bind to troponin but, rather, to a protein called calmodulin. 3  The calcium-calmodulin complex 'activates' myosin which then binds to actin & contraction (swivelling of cross-bridges) begins. TROPONIN-Troponin molecules have binding sites for calcium ions. 2  When a calcium ion fills this site it causes a change in the shape and position of TROPONIN. 3  And, when TROPONIN shifts, it pulls the TROPOMYOSIN to which it is attached.