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Orchitis (or-KIE-tis) is an inflammation of one or both testicles. It is usually caused by a bacterial infection or by the mumps virus. Bacterial orchitis can be caused by sexually transmitted infections (STIs), particularly gonorrhea or chlamydia. Bacterial orchitis often results from epididymitis, an inflammation of the coiled tube (epididymis) at the back of the testicle that stores and carries sperm. In that case, it's called epididymo-orchitis.
Viral mumps is the most common cause of orchitis. Bacterial infections associated with the disorder are tuberculosis, syphilis, gonorrhea, and chlamydia. A mechanical injury to the groin area may also cause orchitis. Fifteen to twenty-five percent of males past the age of puberty with mumps develop orchitis. Epididymo-orchitis (inflammation of both testes and part of the spermatic duct) is the most common bacterial type of Orchitis.