Over 25 alkaloids have been isolated from kratom. The most abundant alkaloids consist of three indoles and two oxindoles. The three indoles are mitragynine, paynanthine, and speciogynine-the first two of which appear to be unique to this species. The two oxindoles are mitraphylline and speciofoline.
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The following languages are listed as having 50 million or more native speakers in the 2015 edition of Ethnologue, a language reference published by SIL International. Speaker totals are generally not reliable, as they add together estimates from different dates.