Pseudoscience describes any belief system or methodology which tries to gain legitimacy by wearing the trappings of science, but fails to abide by the rigorous methodology and standards of evidence that are the marks of true science.
1 Flex-fuel hybrid electric and flex-fuel plug-in hybrid are two types of hybrid vehicles built with a combustion engine capable of running on gasoline, E-85, or E-100 to help drive the wheels in conjunction with the electric engine or to recharge the battery pack that powers the electric engine.
1 Jet suggests using 91 or 93 octane gasoline to achieve stated maximum power gains with the Performance Module.  Flex Fuel Vehicles: fueling with E85 is not recommended in conjunction with your Jet unit. Burning E85 reduces efficiency and power compared to using gas, which nullifies the effect of Jet's programming.