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It is important to distinguish between a normal decline of testosterone levels and hypogonadism. Signs and symptoms of low testosterone include: 1  Change in sleep patterns: insomnia or sleep disturbances. 2  Physical changes: increased body fat and reduced muscle bulk. 3  Sexual changes: reduced sexual desires, sexual dysfunction, or infertility.
Psychological Side Effects. 1  There are a few potential psychological side effects associated with testosterone boosters that should be noted as well. 2  Mood swings are the most commonly reported psychological side effect of testosterone boosters. 3  Depression has sometimes been reported while using testosterone boosters.