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Histones are alkaline (basic pH) proteins. They are found inside the nucleus of eukaryotic cells. Their purpose is to package DNA into structural units called nucleosomes.They are the main proteins in chromatin (a combination of DNA and protein), which makes up the contents of a cell nucleus.2A, H2B, H3, and H4 are the core histones, and H1 and H5 are the linker histones. The core histones form the center of the nucleosome, hence the term 'core'. The linker histones are found at the entrance and exit sites of the nucleosome and lock the DNA in place, hence the term 'linker'.
1 The binding of the chromosomal DNA to histones is the first level of packaging. 2  The DNA-histone protein complex is called the chromatin. The DNA-histone protein complex is called the chromatin. 2  There are 5 types of histones namely, H1, H2A, H2B, H3 and H4. 3  These are basic proteins (25% of basic amino acids lysine and arginine) and negatively charged DNA (due to the presence of phosphate group) can easily bind to these positively charged proteins.