I have Googled like mad, but can't find a clear answer on this! I bought a spaghetti squash about 5 weeks ago meaning to cook it and never got around to it.I have never eaten it before, and my husband was skeptical, so I kept putting it off. Anyway, everything I read says that it will keep a long time..eople used to keep squash and other foods in their cellars for long periods of time. If it's been kept cool, has no soft or dark spots on, and looks okay when you cut into it (today or tomorrow!!), I'd say go ahead and eat it.
1 Because alpha motor neurons are the only way to stimulate extrafusal muscle fibers, the loss of these neurons causes a decrease in muscle tone. 2  Hyporeflexia. 3  The myotatic (stretch) reflex is weak or absent with lower motor neuron disorders, because the alpha motor neurons that cause muscle contraction are damaged. When alpha motor neurons die, the muscle fibers that they innervate become deprived of necessary trophic factors and eventually the muscle itself atrophies. 2  Weakness. 3  Because of the damage to alpha motor neurons and the atrophy of muscles, weakness is profound in lower motor neuron disorders.
A brief description of the symptoms of some of the more common MNDs follows. Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease or classical motor neuron disease, is a progressive, ultimately fatal disorder that disrupts signals to all voluntary muscles.pinal muscular atrophy (SMA) is a hereditary disease affecting the lower motor neurons. It is an autosomal recessive disorder caused by defects in the gene SMN1, which makes a protein that is important for the survival of motor neurons (SMN protein).