Prior to the mid-1950s regular dental hygiene didnât hold much promise for oral health. Toothpastes had been formulated since ancient times with ingredients ranging from burnt oyster shells to ground areca nuts. Americans using a soap-and-water-based dentifrice were developing around 700 million cavities a year.
Drug delivery into muscle using an autoinjector, akin to the EpiPen used to treat serious allergic reactions, is faster and may be a more effective way to stop status epilepticus, a prolonged seizure lasting longer than five minutes, according to a study sponsored by the National Institutes of Health.
1 These seizures are called secondary generalized because they start in one area and spread to both sides of the brain. 2  They usually last 1 to 3 minutes, but it may take a lot longer for a person to recover. These seizures generally last 1 to 3 minutes. 2  A tonic-clonic seizure that lasts longer than 5 minutes is a medical emergency. 3  It may be difficult to distinguish these seizures from primary generalized tonic-clonic seizures, especially if they occur during sleep or are not seen by anyone else.