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Histones are alkaline (basic pH) proteins. They are found inside the nucleus of eukaryotic cells. Their purpose is to package DNA into structural units called nucleosomes.They are the main proteins in chromatin (a combination of DNA and protein), which makes up the contents of a cell nucleus.2A, H2B, H3, and H4 are the core histones, and H1 and H5 are the linker histones. The core histones form the center of the nucleosome, hence the term 'core'. The linker histones are found at the entrance and exit sites of the nucleosome and lock the DNA in place, hence the term 'linker'.
There are four types of histones found in chromatin: H2A, H2B, H3, and H4. Two of each histone comprise a protein core, a nucleosome, which DNA wraps around twice.What results is a bead on a string model in which the nucleosomes are the beads and the linker DNA binds them together.Another characteristic of histones are the protein tails that extend outward from the bead..The tails and the degree of their acetylation is an important factor in gene expression.here are four types of histones found in chromatin: H2A, H2B, H3, and H4. Two of each histone comprise a protein core, a nucleosome, which DNA wraps around twice.