Carpal Tunnel Syndrome And Tarsal Tunnel Syndrome Carpal tunnel syndrome is a condition in which irritation of the wrist's median nerve causes tingling and numbness of the thumb,...learn more Â». In This Article.
1 Argyria-characterised by a metallic, slate-grey or blue-grey pigmentation. 2  The hyperpigmentation is most apparent in the UV-exposed areas of skin, especially the forehead, nose, and hands, as well as mucous membranes. 3  Argyria results from prolonged contact with or ingestion of silver salts.
Skin pigmentation disorders affect the color of your skin. Your skin gets its color from a pigment called melanin. Special cells in the skin make melanin. When these cells become damaged or unhealthy, it affects melanin production. Some pigmentation disorders affect just patches of skin. Others affect your entire body. If your body makes too much melanin, your skin gets darker.