As folate is vital in the first trimester of pregnancy for healthy fetal development, the use of antifolates is strongly contraindicated in pregnancy and carries significant teratogenic risk. Low doses of methotrexate can deplete folate stores and cause side-effects that are similar to folate deficiency.
Cause of Adult Mumps. Adult mumps is caused by an infection with the mumps virus, which is found worldwide. The mumps virus is an RNA (ribonucleic acid) virus from the family Paramyxovirus of the genus Rubulavirus. The mumps virus only infects humans.
Mumps causes swelling in the parotid glands on either side of the neck. The cheeks can become quite swollen. Fatigue, weakness and fever can occur. Mumps can make eating painful. Mumps may cause dangerous complications, including encephalitis, meningitis, pancreatitis, inflammation of the testicles or ovaries, and hearing loss.