Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
Water's density maximum is a product of the same phenomenon. Close to the freezing point, the water molecules start to arrange locally into ice-like structures. This creates some openness in the liquid water, which tends to decrease its density.
Ice melts when heat energy causes the molecules to move faster, breaking the hydrogen bonds between molecules to form liquid water. In the melting process, the water molecules actually absorb energy. This is why an ice cube melts more quickly on the outside and retains its coldness and solidity longer at the center: melting is a cooling process. As more heat is introduced, the ice will continue to melt, and if the temperature exceeds the boiling point, about 100 degrees Celsius (212 degrees Fahrenheit), more hydrogen bonds between water molecules will break completely, creating water vapor.