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In general for most vegetables you want at least 12 inches deep, for tomatoes and large squash 18 inches deep, for herbs and small flowers 8 inches deep. Longer and wider is always better because the soil stays more evenly moist (up to 8ft long x 4 ft wide for raised beds and 8ft long x 3 ft wide for boxes).
Rows of tomatoes should be at least 5 feet apart, or wider if space allows. In the row, space the plants 18 to 36 inches apart, using the wider measurement if you use cages. We grow our tomatoes up wire fences so we can fan them out and because almost all the varieties we grow are tall, indeterminate types.