Chronic kidney disease speeds up hardening of the arteries (atherosclerosis) and increases the risk of stroke, heart attack, and heart failure. Heart disease is the most common cause of death in people with kidney failure. Bone disease (osteodystrophy). Abnormal levels of substances, such as calcium, phosphate, and vitamin D, can lead to bone disease.
the act of referring, or the state of being referred; as, reference to a chart for guidance. Reference (noun). that which refers to something; a specific direction of the attention; as, a reference in a text-book. Reference (noun).
A pointer is a computer science term for a variable that, instead of holding a bit of information, holds an address to where that information can be found in a computer's memory. You can imagine the variable as a signpost that \points\ to where the information can be found.