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Freebase(0.00 / 0 votes)Rate this definition: OSIsoft. OSIsoft, LLC is a worldwide manufacturer of Application software for real-time data infrastructure solutions, called the PI System. Founded in 1980, OSIsoft, LLC is privately held and headquartered in San Leandro, CA, with operations worldwide.
The Open Systems Interconnection OSI model divides computer network architecture into 7 layers in a logical progression, from Physical to Application. The Open Systems Interconnection OSI model divides computer network architecture into 7 layers in a logical progression, from Physical to Application.