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Alanine aminotransferase (ALT): An enzyme that is normally present in liver and heart cells. ALT is released into blood when the liver or heart is damaged.The blood ALT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack).Some medications can also raise ALT levels.LT is released into blood when the liver or heart is damaged. The blood ALT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack).
Aminotransfer reaction between an amino acid and an alpha-keto acid. Transamination (or aminotransfer) is a chemical reaction that replaces an amine functional group with another amine. In many applications, an amino acid is the substrate. The other substrate is a keto acid, which contains a keto (=O) group. In transamination, the NH 2 group on one molecule is exchanged with the =O group on the other. The original amino acid converts to a keto acid, and the keto acid converts to an amino acid.