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Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability (cognition).Adult-onset Huntington disease, the most common form of this disorder, usually appears in a person's thirties or forties.n rare cases, an individual with Huntington disease does not have a parent with the disorder. As the altered HTT gene is passed from one generation to the next, the size of the CAG trinucleotide repeat often increases in size.
Like many so-called 'genetic' disorders, Huntington's disease only emerges when certain protective genes are suppressed while other harmful genes are activated, explained Mike Adams, a consumer health advocate and nutrition author.