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The most common short-term side effects of radiation therapy for prostate cancer include fatigue, slight reddening of the skin in the treatment area, temporary lowering of blood counts, and urinary and bowel side effects. Brachytherapy and radium 223 dichloride may have some additional or different side effects.
1 Hormone therapy given before other treatments is called neoadjuvant hormone therapy. 2  Men with early-stage prostate cancer that has an intermediate or high risk of recurrence often receive hormone therapy before or during radiation therapy, in addition to receiving hormone therapy after radiation therapy.inally, hormone therapy used alone is also the standard treatment for men who are found to have metastatic disease (i.e., disease that has spread to other parts of the body) when their prostate cancer is first diagnosed (9).