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Medical Definition of ALANINE AMINOTRANSFERASE. : an enzyme which promotes transfer of an amino group from glutamic acid to pyruvic acid and which when present in abnormally high levels in the blood is a diagnostic indication of liver diseaseâabbreviation ALT; called also glutamic pyruvic transaminase.weet. : an enzyme which promotes transfer of an amino group from glutamic acid to pyruvic acid and which when present in abnormally high levels in the blood is a diagnostic indication of liver diseaseâabbreviation ALT; called also glutamic pyruvic transaminase.
In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver damage. Other terms employed include transaminasemia and transaminitis, although some sources consider the latter pathologically meaningless.n medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver damage. Other terms employed include transaminasemia and transaminitis, although some sources consider the latter pathologically meaningless.