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This condition can be caused by certain medications and by infections. In some cases, it is caused by a cancer or precancerous condition. Myelofibrosis, bone marrow scarring that can result from various hematologic cancers, typically leads to low blood counts. Pancytopenia can also be caused by aplastic anemia, a bone marrow failure disorder that affects blood cell production.
When not enough platelets are made, the platelet count in your blood is too low. Chemotherapy and some radiation therapy can cause this temporarily. These cancer treatments can slow the production of platelets in the bone marrow. Another cause of a low platelet count is cancer of the bone marrow.