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Histones are alkaline (basic pH) proteins. They are found inside the nucleus of eukaryotic cells. Their purpose is to package DNA into structural units called nucleosomes.They are the main proteins in chromatin (a combination of DNA and protein), which makes up the contents of a cell nucleus.2A, H2B, H3, and H4 are the core histones, and H1 and H5 are the linker histones. The core histones form the center of the nucleosome, hence the term 'core'. The linker histones are found at the entrance and exit sites of the nucleosome and lock the DNA in place, hence the term 'linker'.
histone / histones. Under the microscope in its extended form, chromatin looks like beads on a string. The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer.uclear DNA does not appear in free linear strands; it is highly condensed and wrapped around histones in order to fit inside of the nucleus and take part in the formation of chromosomes.