Which type of reins a rider uses, split reins or one rein, is a matter of personal preference. Split reins are commonly seen in the Western riding disciplines, although some Western riders might use one rein. Split reins are heavily preferred by most working cowboys and cowgirls.
Antimicrotubule agent, mitotic inhibitor Oncology An agent that inhibits cancer growth by stopping cell division Pharmacology A drug that inhibits or blocks mitosis in a particular phase of the cell cycleâeg, metaphase arrest caused by colchicine and vinca alkaloids. See Chemotherapy.
The inhibitor chemicallyresembles a (one of the) substrate(s) and binds in the active site in the same way as thesubstrate(s) binds. The inhibitor, however, has a functional group, ususally a leaving group,that is replaced by a nucleophile in the enzyme active site.herefore thistype of inhibition is called suicide inhibition or affinity labeling and the inhibitor is called a suicide inhibitor. This reaction with the suicide inhibitor removes active enzyme from the system; this removal is measured as inhibition.