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Quadriceps weakness can be caused by various injuries to the knee or hips, acquired myopathies (diseases that affect muscle tissue) such as Lyme disease and poliomyelitis, inherited myopathies such as certain muscular dystrophies and stroke, or neurological diseases such as multiple sclerosis or Bellâs palsy.
Quadriceps strain explained. The quadriceps muscles are the muscles on the front of the thigh. They consist of the vastus lateralis, vastus medialis, vastus intermedius and the rectus femoris. A strain is a tear in the muscle. thigh strain or quadriceps strain is a tear in one of the quadriceps muscles at the front of the thigh. It can range from a mild discomfort to a full blown tear of most of the muscle resulting in severe pain and inability to walk.