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This condition can be caused by certain medications and by infections. In some cases, it is caused by a cancer or precancerous condition. Myelofibrosis, bone marrow scarring that can result from various hematologic cancers, typically leads to low blood counts. Pancytopenia can also be caused by aplastic anemia, a bone marrow failure disorder that affects blood cell production.
Low white blood cell count. Some cancer treatments, mainly chemotherapy, may cause a decrease in your body's white blood cells. Cancers that affect the blood and bone marrow can also cause a decrease in the count.