As folate is vital in the first trimester of pregnancy for healthy fetal development, the use of antifolates is strongly contraindicated in pregnancy and carries significant teratogenic risk. Low doses of methotrexate can deplete folate stores and cause side-effects that are similar to folate deficiency.
Cause of Adult Mumps. Adult mumps is caused by an infection with the mumps virus, which is found worldwide. The mumps virus is an RNA (ribonucleic acid) virus from the family Paramyxovirus of the genus Rubulavirus. The mumps virus only infects humans.
Causes Of Thrush In Adults. 1  Thrush or candida infection occurs in an adult only when his immune system is compromised. 2  Excess use of antibiotics can also destroy the good bacteria present in the intestine and allow the growth of yeast. 3  A hormonal change especially in women is the reason of vaginal thrush.