Additional doses may be needed in people with poor immune function but are not necessary for most people. In those who have been exposed to the hepatitis B virus but not immunized, hepatitis B immune globulin should be given in addition to the vaccine. The vaccine is given by injection into a muscle.
Updated October 30, 2014. Neither had I until a friend with multiple sclerosis (who sees the same neurologist that I do) called me to tell me that it had changed her life.. Nuvigil (armodafinil) is a derivative of Provigil (modafinil), which many people with MS take to combat MS-related fatigue. My ears perked up at the excitement in my friend's voice. She went on to tell me that she couldn't tolerate Provigil, as it left her too wakeful to sleep at night.
Cobimetinib is approved for use in combination with vemurafenib (trade name Zelboraf) for the treatment of advanced melanoma that cannot be removed by surgery or which has spread to other parts of the body, provided that the melanoma has an abnormal gene, with a mutation of BRAF (either V600E or V600K).