What physicians need to know about restrictive covenants. Roy W. BreitenbachThe mention of restrictive covenants provokes an almost visceral reaction among most physicians. But keep in mind these covenants are, for the most part, enforceable.
An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. medicinal enzyme inhibitor is often judged by its specificity (its lack of binding to other proteins) and its potency (its dissociation constant, which indicates the concentration needed to inhibit the enzyme). A high specificity and potency ensure that a drug will have few side effects and thus low toxicity.
1 This binding to an allosteric site changes the conformation of the enzyme so that the affinity of the substrate for the active site is reduced. 2  These inhibitors lower the K m and V m. 3  File:Uncompetitive inhibition.docx. 4  mixed inhibition the inhibitors can bind to the enzyme at the same time as the enzyme substrate.