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Procedures such as laceration repair, which at one time required the use of painful infiltrative anesthetics, can now be accomplished safely and comfortably with the use of topical anesthetics. An additional advantage of topical anesthetics in laceration repair is that wound margins are not distorted.
The goal of Preparation H and similar products is to make bowel movements less uncomfortable. Drugs.com reveals Preparation H blocks pain signals in nerve endings in the skin, and the ointment is a topical anesthetic. The risk of it interacting with other medications is low because Preparation H does not enter the bloodstream. People with certain medical conditions may not be able to take Preparation H, according to Drugs.com.