Carpal Tunnel Syndrome And Tarsal Tunnel Syndrome Carpal tunnel syndrome is a condition in which irritation of the wrist's median nerve causes tingling and numbness of the thumb,...learn more Â». In This Article.
1 Argyria-characterised by a metallic, slate-grey or blue-grey pigmentation. 2  The hyperpigmentation is most apparent in the UV-exposed areas of skin, especially the forehead, nose, and hands, as well as mucous membranes. 3  Argyria results from prolonged contact with or ingestion of silver salts.
An Overview of Human Pigmentation. Human skin contains specialized cells, called melanocytes, which are located at the base of the epidermis. These cells are programmed to manufacture a brown pigment, called melanin, in response to exposure of skin to sunlight.