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Lack of evidence: There is little evidence to suggest that low dose Seroquel is an effective treatment for insomnia. Despite the drugâs perception of being an effective treatment for insomnia, there is minimal evidence in support of these claims.
Seroquel is the brand name of the generic drug q uetiapine, a prescription drug used to treat schizophrenia and bipolar disorder (formerly called manic-depression). Seroquel changes the levels of neurotransmitters (naturally occurring brain substances) including serotonin and dopamine.ther side effects of Seroquel may include: 1  Headache. 2  Body aches. 3  Weakness. 4  Vomiting. 5  Increased appetite and weight gain. 6  Stuffy nose. 7  Irritability. 8  Trouble concentrating, thinking, or speaking clearly.