1 AbstralÂ® was launched in the principal European markets during the course of 2009 and generated sales of Â£14.1m in the first ten months of 2010 in Europe.  In the top four European markets (Source: IMS data June 2010). AbstralÂ® achieved in June 2010 a 24% market share by tablet volume of short-acting fentanyl products.
In the 15th century, the Renaissance spread with great speed from its birthplace in Florence, first to the rest of Italy, and soon to the rest of Europe. The invention of the printing press by German printer Johannes Gutenberg allowed the rapid transmission of these new ideas.arly Renaissance, mostly in Italy, bridges the art period during the fifteenth century, between the Middle Ages and the High Renaissance in Italy. It is generally known that Renaissance matured in Northern Europe later, in the 16th century.
Confidence votes 94.7K. The Bubonic Plague originated in China. It was spread by the fleas carried by rats going aboard ships and they were transported to Italy, Greece and France, when the rats left the ships entering cities and gave us the Bubonic Plague.he Bubonic Plague spread from China and East Asia to Europe through the Silk Road and arrived in the Ukraine. It also spread from fleas upon rats aboard merchant ships, and i â¦ s believed to have spread from Sicily. From both these places, the disease spread enormously and claimed over half of the population of Europe.