As folate is vital in the first trimester of pregnancy for healthy fetal development, the use of antifolates is strongly contraindicated in pregnancy and carries significant teratogenic risk. Low doses of methotrexate can deplete folate stores and cause side-effects that are similar to folate deficiency.
Cause of Adult Mumps. Adult mumps is caused by an infection with the mumps virus, which is found worldwide. The mumps virus is an RNA (ribonucleic acid) virus from the family Paramyxovirus of the genus Rubulavirus. The mumps virus only infects humans.
Causes. Short bowel syndrome in adults is usually caused by: 1  Crohn's disease, an inflammatory disorder of the digestive tract. 2  Volvulus, a spontaneous twisting of the small intestine that cuts off the blood supply and leads to necrosis or tissue death. 3  Cancer of the small intestine.hort bowel syndrome caused by the surgical removal of a portion of the bowel may be a temporary condition, due to the adaptive property of the small intestine. In a process called intestinal adaptation, physiological changes to the remaining portion of the small intestine occur to increase its absorptive capacity.