In 1980 Alberca et al. described a patient with a syndrome of increased muscle irritability, who presented ondulating muscle rolling movements and electrically silent cramps, myoedema and muscle reactions to mechanical stimulation similar to myotonic response, suggesting a disfunction at myofibrillar level.
For c-3po, it was a costume, Anthony Daniels played c-3po: For R2-D2, It was a costume and a remote controlled robot. CGI was also used in the prequel trilogy. So, they had Kenny Baker to play him : And from Portrayal section of wookieepedia article on R2-D2 :
1 Premiered: July 12, 2002. 2  Rating: TV-PG.  Premise: An ex-cop suffering from obsessive-compulsive disorder solves crimes with various (and usually exasperated) sidekicks in tow in this first-rate mystery with a breakout Emmy-winning star in Tony Shalhoub. The 'defective detective' may have an abundance of pâ¦ (more)