Collagenase is potentially irreversibly inactivated at pH <5 and reversibly inactivated at pH â¥8.5; activity can be restored by return of pH to 7.4.a. Collagenase can be destroyed by other proteolytic enzymes or by exposure to temperatures >56Â°C.a.
Splenectomy is a surgical procedure to remove your spleen. The spleen is an organ that sits under your rib cage on the upper left side of your abdomen. It helps fight infection and filters unneeded material, such as old or damaged blood cells. The most common reason for splenectomy is to treat a ruptured spleen, often caused by an abdominal injury.
Enlarged spleen: Causes, symptoms and treatments. Enlarged spleen, also called hypersplenism or splenomegaly, happens when the spleen grows in size because of infection or other medical conditions, including blood disorders. The spleen sits under your rib cage in the upper left part of your abdomen toward your back.