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Symptoms and Causes of Moon Facies. Moon facies may cause the face to gradually become round, full, or puffy. The sides of your face may become so round from the buildup of fat that the ears can't be seen from the front of your face. Fat deposits in the sides of the skull can also make the face look rounder.
An allergic reaction to oysters or other shellfish could cause puffy lips. Exposure to common allergens may cause the lips to become itchy or puffy, in addition to other symptoms. Environmental allergies may cause runny noses and puffy lips. An infection can cause lips to swell and become puffy. Some people suffer from allergies that are triggered by pet dander. An allergic reaction to toothpaste may cause puffy lips.