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Japanese encephalitis (JE) is the leading cause of viral encephalitis in Asia, with up to 70,000 cases reported annually. Case-fatality rates range from 0.3% to 60% and depend on the population and age. Rare outbreaks in U.S. territories in the Western Pacific have also occurred.
Encephalitis is inflammation of the brain. It is usually caused by a viral infection. In the UK, the most common virus to cause encephalitis is herpes simplex virus. Symptoms usually start with the common symptoms of a viral infection such as high temperature (fever), headache, muscle aches, feeling tired and feeing sick (nausea). Confusion, drowsiness and eventually coma can develop.