In addition to the sciatic nerve, many other nerve roots in the lumbar (lower) spine serve the legs, so a bulging disc at any point between the five vertebrae of the lumbar spine (L1 to L5) â or between the bottom of the lumbar spine and sacrum (L5 to S1) could result in leg pain.
A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.Fibroblasts are the most common cells of connective tissue in animals.ibroblasts and fibrocytes are two states of the same cells, the former being the activated state, the latter the less active state, concerned with maintenance and tissue metabolism.
Loose connective tissue is found in all parts of the body and is responsible for binding various structures together, such as muscle fibers to muscle fibers, and skin to underlying tissues. Various membranes and mesenteries are also composed of loose connective tissue.Study the slide of areolar tissue to the right.he most common cell type is the fibroblast. These cells are responsible for production of the extra-cellular fibers and matrix. There are other cell types in loose connective tissue but they are difficult to see in the preparations you will be using.