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Treatment of Depression. The recommended initial dosage of trazodone is 150 mg/day taken in divided doses. The dose may be adjusted every three to four days with increment of 50 mg/day. The maximum daily dose for outpatients is 400 mg/day in divided doses.
A: Trazodone is a medication used to treat depression, insomnia, mood disorders, or anxiety. The most common side effects of trazodone are headache, nausea, stomach upset, fatigue, nightmares, and changes in appetite.