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The major target end organs for parathyroid hormone (PTH) action are the kidneys, skeletal system, and intestine. The primary response to parathyroid hormone (PTH) by the kidney is to increase renal calcium resorption and phosphate excretion.
PTH levels that are too high or too low can cause problems with the kidneys and bones and cause changes in calcium and vitamin D levels. Tests for calcium and phosphorus levels in the blood may be done at the same time as a PTH test.