The Structures of Life in PDF Chapter 4: Structure-Based Drug Design: From the Computer to the Clinic In 1981, doctors recognized a strange new disease in the United States. The first handful of patients suffered from unusual cancers and pneumonias.
A recent randomized controlled trial found that vitamin K supplementation in conjunction to vitamin D supplementation reduced the progression of atherosclerosis in patients with chronic kidney disease (CKD) significantly more so than supplementing with vitamin D alone.
The problem: Vitamin B12 deficiency can boost blood levels of homocysteine, an amino acid implicated as a strong risk factor for heart disease and stroke. Studies have suggested that high homocysteine levels can promote blockages in arteries over time, possibly leading to heart disease and stroke.