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Medical Definition of Sharpey's fiber. : any of the thready processes of the periosteum that penetrate the tissue of the superficial lamellae of bones.
Skeletal muscle fibers can be classified as red fibers, white fibers or intermediate fibers. Red fibers are smaller in diameter; white fibers are larger in diameter. Red fibers have more mitochondria than white fibers. Red fibers make up slow-twitch muscle; white fibers make up fast-twitch muscle.