Patients with hypertensive crises may require immediate reduction in elevated blood pressure to prevent and arrest progressive end-organ damage. The best clinical setting in which to achieve this blood pressure control is in the intensive care unit, with the use of titratable intravenous hypotensive agents.
Implementation of therapeutic hypothermia has its advantages, although complications are associated with its use. Shivering is a common complication that occurs during the induction and rewarming phases of therapeutic hypothermia. Strategies for preventing and managing shivering vary across protocols.
Severe (deep) frostbite. As frostbite progresses, it affects all layers of the skin, including the tissues that lie below. You may experience numbness, losing all sensation of cold, pain or discomfort in the affected area. Joints or muscles may no longer work. Large blisters form 24 to 48 hours after rewarming.