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Commissioned by the US Government in response to ethical failures in medical research, such as the Tuskegee Syphilis Study, the Belmont Report was written by a panel of experts and proposes three principles that should underlying the ethical conduct of research involving human subjects: 1) Respect for persons; 2) Beneficence; and 3) Justice.
Subpart E of the UG and A-21 spell out the Four Cost Principles that apply to all award costs: 1  A cost is allowable when: It serves an Institute business purpose, including instruction, research, and public service. 2  A cost is allocable: When the cost benefits the project that is being charged.