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Treatment of Depression. The recommended initial dosage of trazodone is 150 mg/day taken in divided doses. The dose may be adjusted every three to four days with increment of 50 mg/day. The maximum daily dose for outpatients is 400 mg/day in divided doses.
Trazodone was approved by the FDA in 1982. PRESCRIBED FOR: Trazodone is primarily used for the treatment of depression. It is sometimes prescribed as a sedative, and also is used in combination with other drugs for the treatment of panic attacks, aggressive behavior, agoraphobia, and cocaine withdrawal. Medically Reviewed by a Doctor on 3/27/2015.