A hosted Open Web App delivers all its content from a Web server, in the same way as a conventional Web site, along with an app manifest in the app's root directory. The app manifest provides details about the app such as its description, icons used to identify the installed app and so on.
Raw opium contains some 20 alkaloid substances, one of which is morphine, in a typical yield of 10%. Morphine was first isolated in 1805 by Friedrich SertÃ¼rner, an apothecary's assistant in Paderborn, Germany, however its basic structure was not correctly determined until 120 years later.
Methamphetamine was first synthesized by Nagayoshi Nagai in Japan in the early 1900s. Cocaine is actually natural, like marijuana, and heroin is only semi-synthetic, being only a slightly changed form of morphine. It was first synthesized by C.R. Alder Wright, an English chemist in 1874.