Collagenase is potentially irreversibly inactivated at pH <5 and reversibly inactivated at pH â¥8.5; activity can be restored by return of pH to 7.4.a. Collagenase can be destroyed by other proteolytic enzymes or by exposure to temperatures >56Â°C.a.
Splenectomy is a surgical procedure to remove your spleen. The spleen is an organ that sits under your rib cage on the upper left side of your abdomen. It helps fight infection and filters unneeded material, such as old or damaged blood cells. The most common reason for splenectomy is to treat a ruptured spleen, often caused by an abdominal injury.
Introduction. The spleen is a fist-sized organ found in the upper left side of your abdomen, behind your stomach and left ribs. Some people are born without a spleen or need to have it removed because of disease or injury.he spleen has a few important functions: 1  it fights any invading germs in the blood (the spleen contains infection-fighting white blood cells). 2  it controls the level of white blood cells, red blood cells and platelets (platelets are small cells that form blood clots).