Many causes: Elevated concentrations of plasma D-dimer can be caused by many conditions to include arterial (stroke, atrial fib, etc) or venous blood clots (DVT), pulmonary embolism, infection (sepsis/ inflammatory response), normal pregnancy, pre/eclampsia, malignancy, surgery, tissue necrosis, congestive heart failure, liver disease, intravascular coagulation.
Media-fill testing (also called aseptic manipulation testing) is performed to measure the ability of procedures, personnel and equipment to successfully produce a sterile end product. This test is a simulation of the actual compounding taking place in a facility.
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