Three years on ... and three key questions. The Breakthrough Therapy Designation (BTD) came into force in July 2012 after the Food and Drug Administration Safety and Innovation Act (FDASIA) was approved by Congress.
Sure, visitors to Southern California come for the sun, but they also come for the world's best family-friendly theme parks, all located within an easy drive of one another. And with one easy-to-use CityPASS, you'll get a combination of the very best attractions at a great savings. CityPASS is valid for 14 days starting with the first day of use, giving you and your family plenty of time to truly experience SoCal and make lots of memories to take home.
Playa del Carmen (Spanish pronunciation: ) is a city located along the Caribbean Sea in the municipality of Solidaridad, in the state of Quintana Roo, Mexico. It is a popular tourist area in eastern Mexico. Playa del Carmen features a wide array of tourist activities due to its geographical location in the Riviera Maya. It has also been the destination of PGA Tour golf tournaments and the set location for various television shows.