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Alpha type receptors. Alpha receptors are found in smooth muscle surrounding blood vessels of peripheral circulation. Stress â epinephrine â muscles contract â constrict peripheral circulation â direct blood to essential organs for responding to stress (heart, lungs, skeletal muscle).lpha type receptors. Alpha receptors are found in smooth muscle surrounding blood vessels of peripheral circulation. Stress â epinephrine â muscles contract â constrict peripheral circulation â direct blood to essential organs for responding to stress (heart, lungs, skeletal muscle).
NE can also bind to Î± 1-adrenoceptors found on myocytes to produce small increases in inotropy. Circulating catecholamines (epinephrine) released by the adrenal medulla also bind to these same alpha and beta adrenoceptors in the heart. In addition to sympathetic adrenergic nerves, the heart is innervated by parasympathetic cholinergic nerves derived from the vagus nerves.