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Quick Answer. Hand, foot and mouth disease in adults is caused by transmission from a person infected with the Coxsackievirus, according to Mayo Clinic. The virus is transmitted by personal contact such as exposure to nasal secretions, saliva, fluid from blisters, throat discharge or stool of an infected individual. Keep Learning.
Learn more about hand foot mouth disease symptoms 1  Â». Hand, foot, and mouth disease is a viral infection. 2  Hand, foot, and mouth disease produces a characteristic rash on the hands, feet, and in the mouth.  Hand, foot, and mouth disease often occurs in the spring and fall.