In addition to the sciatic nerve, many other nerve roots in the lumbar (lower) spine serve the legs, so a bulging disc at any point between the five vertebrae of the lumbar spine (L1 to L5) â or between the bottom of the lumbar spine and sacrum (L5 to S1) could result in leg pain.
A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.Fibroblasts are the most common cells of connective tissue in animals.ibroblasts and fibrocytes are two states of the same cells, the former being the activated state, the latter the less active state, concerned with maintenance and tissue metabolism.
The primary purpose of fibrous connective tissue is to provide support and shock absorption to our bones and organs. This slide is a histological section of fibrous connective tissue.