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Author: Dr Amanda Oakley, Dermatologist, Hamilton, New Zealand,1999. Exfoliative keratolysis is a common skin condition in which there is focal peeling of the palms and less often the soles. It is also known as âkeratolysis exfoliativaâ, dyshidrosis lamellosa sicca, and âfocal palmar peelingâ.
Reactive arthritis, a form of arthritis that often occurs after an infection of the genital, gastrointestinal system or urinary system, can cause a rash or hard nodules to develop on the palms of the hands or on the soles of the feet. Reactive arthritis also can affect the ankle, the heel and the toes, causing pain and swelling.