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The major target end organs for parathyroid hormone (PTH) action are the kidneys, skeletal system, and intestine. The primary response to parathyroid hormone (PTH) by the kidney is to increase renal calcium resorption and phosphate excretion.
PTH is not the only thing in your blood that can suggest that you may have a parathyroid tumor. Because PTH helps regulate your calcium and phosphorus, unusual blood levels of those minerals may also suggest that you have one of these tumors.