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Therefore, a large left-to-right shunt through a patent ductus arteriosus (PDA) results in left atrial and left ventricular enlargement. The pulmonary veins and the ascending aorta can also be dilated with a sufficiently large patent ductus arteriosus (PDA).
Intracardiac shunts are the most common form of congenital heart lesion and are often diagnosed in otherwise healthy adults. They are associated with increased pulmonary blood flow, which can lead to right heart chamber enlargement and arrhythmias, and with pulmonary hypertension.