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Medical Definition of Sharpey's fiber. : any of the thready processes of the periosteum that penetrate the tissue of the superficial lamellae of bones.
(type 2b). called white fibers because they have less myoglobin and a poorer blood supply. reduced respiratory capacity, so they are fatigable. (type 2a). a fast twitch fatigue resistant fiber. they have the fast twitch associated with white fibers as well as the oxidative capacity associated with red fibers.