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Step 3. Talk to your doctor about possible medical causes for the puffiness. Certain medications can cause you to retain water, and allergies, conjunctivitis and allergies --such as hay fever--can cause your face to look puffy. If thereâs a medical cause behind the problem, your health care provider will recommend a change in medication or other adjustments to fix the problem.
Conjunctivitis may also cause facial swelling. Conjunctivitis is redness and swelling of the conjunctiva, the mucous membrane that covering the eyeball and under surface of the eyelid. Drug reactions. Drugs such as aspirin, penicillin, sulfa, glucocorticoids, and others are common fluid retention in the face causes. Further reading Allergic Reaction Face Swelling and Brain Cancer and Face Swelling-Steroids to Treat Hydrocephalus.