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In most cases, doctors do not know the cause of restless legs syndrome; however, they suspect that genes play a role. Nearly half of people with RLS also have a family member with the condition. Other factors associated with the development or worsening of restless legs syndrome include: Chronic diseases.
Lightheadedness has many causes, including: 1  Allergies. 2  Illnesses such as the flu or colds. 3  Vomiting, diarrhea, fevers, and other illnesses that cause dehydration.  Very deep or rapid breathing 1  (hyperventilation). Anxiety and stress.  The use of tobacco, alcohol, or illegal drugs.