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Step 3. Talk to your doctor about possible medical causes for the puffiness. Certain medications can cause you to retain water, and allergies, conjunctivitis and allergies --such as hay fever--can cause your face to look puffy. If thereâs a medical cause behind the problem, your health care provider will recommend a change in medication or other adjustments to fix the problem.
Medications or substances causing Face swelling. The following drugs, medications, substances or toxins are some of the possible causes of Face swelling as a symptom. This list is incomplete and various other drugs or substances may cause your symptoms (see Face swelling). Always advise your doctor of any medications or treatments you are using, including prescription, over-the-counter, supplements, herbal or alternative treatments.