A hosted Open Web App delivers all its content from a Web server, in the same way as a conventional Web site, along with an app manifest in the app's root directory. The app manifest provides details about the app such as its description, icons used to identify the installed app and so on.
Raw opium contains some 20 alkaloid substances, one of which is morphine, in a typical yield of 10%. Morphine was first isolated in 1805 by Friedrich SertÃ¼rner, an apothecary's assistant in Paderborn, Germany, however its basic structure was not correctly determined until 120 years later.
The first true hypodermic syringe was created by Alexander Wood in 1853. He modified a regular syringe, which at that time was used for treating birthmarks, by adding a needle. He then used this new device for introducing morphine into the skin of patients who suffered from sleeping disorders.