A mature osteocyte contains a single nucleus that is located toward the vascular side and has one or two nucleoli and a membrane. The cell also exhibits a reduced size endoplasmic reticulum, Golgi apparatus and mitochondria, and cell processes that radiate towards the mineralizing matrix.
The Paleolithic was the first era in human history. During it people lived as hunter-gatherers. It is when people learnt to make tools, to use fire, and to clothe themselves. The era produced some amazing artwork, the fabulous cave painting that have been found in Spain and in the Dordogne in southern France.
The Permian, however, represented the last gasp for much early prehistoric life. The period, and the Paleozoic era, came to a calamitous close 251 million years ago, marking a biological dividing line that few animals crossed.he Permian, however, represented the last gasp for much early prehistoric life. The period, and the Paleozoic era, came to a calamitous close 251 million years ago, marking a biological dividing line that few animals crossed.