RE: factored and unfactored load. The rationale for using factored loads and cautious estimates of soil properties is to achieve a desired level of reliability. In the European codes (Eurocodes), both factored loads and cautious estimates of geotechnical values are applied (characteristic values).
Ciprofloxacin dosage for UTI. Adults: 250 mg every 12 hours for 7 to 14 days. Complicated infections require 500 mg every 12 hours. Children 1-17 years of age: 10â20 mg/kg (up to 750 mg) every 12 hours for 10â21 days. Cystitis (bladder infection) in women: The usual dosage is 250 mg every 12 hours for 3 days.
If ciprofloxacin at the dose of 750 mg twice daily cannot be. avoided, the dose of Esbriet should be reduced to 1602 mg daily (two capsules, three times a day). Esbriet should be used with caution when ciprofloxacin is used at a dose of 250 mg or 500 mg once or. twice daily. Esbriet should be used with caution in patients treated with other moderate inhibitors of CYP1A2 (e.g. amiodarone, propafenone).