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Japanese encephalitis (JE) is the leading cause of viral encephalitis in Asia, with up to 70,000 cases reported annually. Case-fatality rates range from 0.3% to 60% and depend on the population and age. Rare outbreaks in U.S. territories in the Western Pacific have also occurred.
Infection with a virus is the main cause of encephalitis. Different types of viruses can cause the illness. For example, West Nile virus can cause encephalitis when a person is bitten by an infected mosquito. Another type is the herpes simplex virus, which is the same virus that causes cold sores and genital herpes.his inflammation can cause symptoms such as confusion, a fever, a bad headache, and a stiff neck. Sometimes it leads to symptoms like seizures and personality changes. It can also cause long-term problems, such as trouble with speech or memory. Encephalitis is uncommon, but it can be deadly.