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Causes of Restlessness: The following medical conditions are some of the possible causes of Restlessness. There are likely to be other possible causes, so ask your doctor about your symptoms. Anxiety - general everyday anxiety may cause restlessness as a symptom. Anxiety disorders - almost all anxiety disorders may cause restlessness symptoms.
We cannot state that an imbalance in serotonin, whether by depletion or misdirection, causes every case of depression or restlessness. But for the cases that include both depression and sleep disruption arising from genetic expression, we can conclude that an imbalance in serotonin causes the disorders.