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(Graphic computer art by Daniel Yuen). A circular bacterial chromosome is a bacterial chromosome in the form of a molecule of circular DNA. Unlike the linear DNA of most eukaryotes, typical bacterial chromosomes are circular. Most bacterial chromosomes contain a circular DNA molecule â there are no free ends to the DNA. Free ends would otherwise create significant challenges to cells with respect to DNA replication and stability.
Many bacteria (and some yeasts or other fungi) also possess looped bits of DNA known as plasmids, which exist and replicate independently of the chromosome. Plasmids have relatively few genes (fewer than 30). The genetic information of the plasmid is usually not essential to survival of the host bacteria.