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Japanese encephalitis (JE) is the leading cause of viral encephalitis in Asia, with up to 70,000 cases reported annually. Case-fatality rates range from 0.3% to 60% and depend on the population and age. Rare outbreaks in U.S. territories in the Western Pacific have also occurred.
Encephalitis is a sudden onset inflammation of the brain. Encephalitis with meningitis is known as meningoencephalitis. Symptoms include headache, fever, confusion, drowsiness, and fatigue. Further symptoms include seizures or convulsions, tremors, hallucinations, stroke, and memory problems. In 2013, encephalitis was estimated to have resulted in 77,000 deaths, down from 92,000 in 1990. The word is from Ancient Greek á¼Î³ÎºÎ­ÏÎ±Î»Î¿Ï, enkÃ©phalos brain, composed of á¼Î½, en, in and ÎºÎµÏÎ±Î»Î®, kephalÃ©, head, and the medical suffix -itis inflammation.