In addition to the sciatic nerve, many other nerve roots in the lumbar (lower) spine serve the legs, so a bulging disc at any point between the five vertebrae of the lumbar spine (L1 to L5) â or between the bottom of the lumbar spine and sacrum (L5 to S1) could result in leg pain.
A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.Fibroblasts are the most common cells of connective tissue in animals.ibroblasts and fibrocytes are two states of the same cells, the former being the activated state, the latter the less active state, concerned with maintenance and tissue metabolism.
Fibrous tissue consists different groups of specialized cells that work together to perform specific functions within the body. These types of tissue â including connective, dense fibrous and reticular â are categorized according to the roles they play. The one constant in this type of tissue is that the fibers work together to create a continuous mesh around various muscle fibers. One type of this tissue is known as fibrous connective tissue. This type of tissue is formed by elastic and collagen fibers and is used to bind other types of body tissues. Ligaments and tendons are made of fibrous connective tissue. There are no living cells in most of this connective tissue.