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Step 3. Talk to your doctor about possible medical causes for the puffiness. Certain medications can cause you to retain water, and allergies, conjunctivitis and allergies --such as hay fever--can cause your face to look puffy. If thereâs a medical cause behind the problem, your health care provider will recommend a change in medication or other adjustments to fix the problem.
Some cosmetics could elicit one side of face swollen. Allergies to insect bites or stings, some drug allergies or allergic rhinitis may also present with one-sided facial swelling. Certain medications like some antibiotics or steroidal treatments may cause facial swelling.