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Japanese encephalitis (JE) is the leading cause of viral encephalitis in Asia, with up to 70,000 cases reported annually. Case-fatality rates range from 0.3% to 60% and depend on the population and age. Rare outbreaks in U.S. territories in the Western Pacific have also occurred.
The most common viral causes of meningo-encephalitis are enteroviruses, arboviruses (the most recognized arbovirus is the West Nile virus), and the herpes virus. Herpes can cause a devastating disease, usually presenting with seizures. In newborns, it can lead to permanent brain damage.he most common viral causes of meningo-encephalitis are enteroviruses, arboviruses (the most recognized arbovirus is the West Nile virus), and the herpes virus. Herpes can cause a devastating disease, usually presenting with seizures. In newborns, it can lead to permanent brain damage.