Graves' disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). Although a number of disorders may result in hyperthyroidism, Graves' disease is a common cause.
Flight time from LAX to JFK is 5 hours 6 minutes. Delta Air Lines is one of the direct flight which takes 5 hours 6 minutes to travel from Los Angeles International Airport (LAX) to John F Kennedy International Airport (JFK). Flight time from New York to Los Angeles (all airports).
F-22 Raptor > U.S. Air Force > Fact Sheet Display. Therefore, to fly from JFK to LHR the F-22 would need to perform at least one aerial refueling, and most likely two (for safety). It would be just under seven hours to make that flight (at a subsonic cruise speed) with two aerial refuelings.