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(Graphic computer art by Daniel Yuen). A circular bacterial chromosome is a bacterial chromosome in the form of a molecule of circular DNA. Unlike the linear DNA of most eukaryotes, typical bacterial chromosomes are circular. Most bacterial chromosomes contain a circular DNA molecule â there are no free ends to the DNA. Free ends would otherwise create significant challenges to cells with respect to DNA replication and stability.
artificial chromosome A type of cloning vector that has some features of true chromosomes and is used to clone relatively large fragments of DNA.Bacterial artificial chromosomes (BACs) are based on the F (fertility) plasmid found naturally in E. coli bacteria (see sex factor).hromosomes, Artificial. Artificial chromosomes are laboratory constructs that contain DNA sequences and that perform the critical functions of natural chromosomes. They are used to introduce and control new DNA in a cell, to study how chromosomes function, and to map genes in genomes.