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In most cases, doctors do not know the cause of restless legs syndrome; however, they suspect that genes play a role. Nearly half of people with RLS also have a family member with the condition. Other factors associated with the development or worsening of restless legs syndrome include: Chronic diseases.
What causes chronic constipation? The truth is that we don't always know what causes chronic constipation. When constipation occurs for unknown reasons, it's often referred to as idiopathic.. However, constipation can also occur as a result of several underlying medical conditions or by medications people take. Some of the causes of constipation include diabetes mellitus, hypothyroidism (underactive thyroid), hypercalcemia, amyloidosis, Parkinson's disease, multiple sclerosis, depression, and immobility.