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Confidence votes 41. Calcium is water soluble, but not fat soluble. It is the fifth most dissolved ion in seawater. On the other hand, fat is soluble into calcium in the body. The calcium will extract the fat from food in the digestive system, and they combine to form a foamy substance which is not absorbed by the body, and so the fat will be flushed out.
But not all vitamins are water-soluble, and the ones that are lipid-soluble, meaning they like to hang around in your body's fat, don't get flushed out. Instead, if you take too much of a lipid-soluble vitamin over a few weeks to a month, they sit in the liver and can build up to toxic levels, causing problems ranging from weak bones to liver damage, according to Katherine Zeratsky, a registered dietician nutritionist at the Mayo Clinic.