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Commissioned by the US Government in response to ethical failures in medical research, such as the Tuskegee Syphilis Study, the Belmont Report was written by a panel of experts and proposes three principles that should underlying the ethical conduct of research involving human subjects: 1) Respect for persons; 2) Beneficence; and 3) Justice.
Federalism is an important idea in the Constitution. We call the Founding Fathers who wrote the Constitution the  Framers  of the Constitution. The Framers wanted to limit the powers of the government, so they separated the powers into three branches: executive, legislative, and judicial.