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Treatment of Depression. The recommended initial dosage of trazodone is 150 mg/day taken in divided doses. The dose may be adjusted every three to four days with increment of 50 mg/day. The maximum daily dose for outpatients is 400 mg/day in divided doses.
Forms of trazodone [edit]. Trazodone tablets are available in 50, 100, 150 and 300 mg strengths. However, the less-frequently prescribed 300 mg strength has been widely discontinued by many pharmaceutical manufacturers as of mid-2015. The active ingredient is trazodone hydrochloride, USP. Inactive ingredients vary by manufacturer.