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Do not put ice or ice water directly on second-or third-degree burns. If blisters form over the burn, do not break them. These things can cause more damage to the skin.
Ice is used when the injury is recent, red, inflamed, or sensitive. Cold therapy can also help relieve any inflammation or pain that occurs after exercise; this is a form of acute inflammation. However, unlike heat, you should apply ice after going for a run. Cold treatment can reduce post-exercise inflammation. Cold therapy can sometimes also help relieve pain in chronic injuries.