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Step 3. Talk to your doctor about possible medical causes for the puffiness. Certain medications can cause you to retain water, and allergies, conjunctivitis and allergies --such as hay fever--can cause your face to look puffy. If thereâs a medical cause behind the problem, your health care provider will recommend a change in medication or other adjustments to fix the problem.
1 allergic-type conditions, such as seasonal allergies, which can cause mild swelling of the skin. 2  Allergic reactions to medications, herbs, or other substances can cause swelling in the face, tongue, and lips. 3  Food allergies can also cause facial swelling.