Perimenopause can last anywhere from one to 10 years. During this time, the ovaries function erratically and hormonal fluctuations may bring about a range of changes, including hot flashes, night sweats, sleep disturbances, and heavy menstrual bleeding.
The thyroid hormones, triiodothyronine (T3) and its prohormone, thyroxine (T4), are tyrosine-based hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism. Iodine is necessary for the production of T 3 and T 4.hyroxine is produced by attaching iodine atoms to the ring structures of tyrosine molecules. Thyroxine (T 4) contains four iodine atoms. Triiodothyronine (T 3) is identical to T 4, but it has one less iodine atom per molecule. Iodide is actively absorbed from the bloodstream by a process called iodide trapping.
About Endotoxins. Endotoxins, which occur in the outer membrane of certain gram-negative bacteria, are not secreted but are released only when the cells are disrupted or destroyed. Endotoxins are complex polysaccharide molecules that elicit an antigenic response, resulting in fever and altered resistance to bacterial infections.