A hosted Open Web App delivers all its content from a Web server, in the same way as a conventional Web site, along with an app manifest in the app's root directory. The app manifest provides details about the app such as its description, icons used to identify the installed app and so on.
Raw opium contains some 20 alkaloid substances, one of which is morphine, in a typical yield of 10%. Morphine was first isolated in 1805 by Friedrich SertÃ¼rner, an apothecary's assistant in Paderborn, Germany, however its basic structure was not correctly determined until 120 years later.
First synthesized in 1932 and patented in 1934, desomorphine was used in Switzerland under the brand name Permonid and was described as having a fast onset and a short duration of action, with relatively little nausea or respiratory depression compared to equivalent doses of morphine.