Police and civil prefects. 1  Praefectus urbi, or praefectus urbanus: city prefect, in charge of the administration of Rome. 2  Praefectus vigilum: commander of the Vigiles. 3  Praefectus aerarii: nobles appointed guardians of the state treasury. 4  Praefectus aerarii militaris: prefect of the military treasury.
Puppies normally get their first shots around 8 weeks old, but they can be given earlier if needed (ie with stray, abandoned pups or those who were formula fed). Three sets of combination vaccinations (a shot that protects against more than one disease) given at 3 week intervals. 8 weeks - first round.
How long a puppy can actually hold her bladder, depends on the puppy's age. In theory, a pup is able to hold her bladder roughly one hour per month of her age. I said in theory as, in my experience, a puppy needs to go a lot more often than once every 2 hours at 8 weeks old. About 10 minutes after your puppy finishes eating, take your puppy to her designated bathroom area. 2  Now wait. 3  Don't play with your puppy just let her walk round and sniff. 4  As soon as she pees or poops pair the action with the appropriate word (I use wee-wee for a pee and go sniff for a poop).