The severity of amyloidosis depends on which organs it affects. It can be life threatening if it causes kidney or heart failure. If the amyloidosis affects the kidneys, their ability to filter the blood becomes impaired. Protein leaks from the blood into the urine. The loss of protein from the blood can cause fluid to leak out of the blood vessels, resulting in swelling in the feet, ankles and calves. Eventually, there is so much damage to the kidneys that they are not able to remove waste products from the body and they fail.
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What causes appendicitis? Appendicitis can have more than one cause, and in many cases the cause is not clear. Possible causes include: Blockage of the opening inside the appendix; enlarged tissue in the wall of your appendix, caused by infection in the gastrointestinal (GI) tract or elsewhere in your body; inflammatory bowel disease