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Treatment of Depression. The recommended initial dosage of trazodone is 150 mg/day taken in divided doses. The dose may be adjusted every three to four days with increment of 50 mg/day. The maximum daily dose for outpatients is 400 mg/day in divided doses.
It is primarily used to treat depression. Common side effects of trazodone include nervousness, agitation (could include irritability), drowsiness, confusion, dizziness, headache, constipation, diarrhea, nausea, dry mouth, and blurred vision.