This chip let the brightness of the Afterburner be controlled using the Game Boy Advance's existing buttons, so there was no need to carve an extra hole in the case to mount a dimmer. Due to the construction of the Game Boy Advance case, the Afterburner light is slightly too narrow to illuminate the screen evenly. This creates what is called the trapezoid effect: a trapezoid-shaped pattern of light across the screen.
Insertion or deletion of a single letter can sometimes cause a frameshift mutation, in which the entire amino acid sequence of the resulting protein is changed. Gene or Region Duplication. Sometimes errors during DNA replication can duplicate an entire gene or region of a genome. This type of error can cause more of a protein to be produced, because after duplication, there are two genes that encode it rather than one.
Deletions involve the loss of DNA sequences. Phenotypic effects of deletions depend on the size and location of deleted sequences on the genome. For instance, deletions that span a centromere result in an acentric chromosome that will most likely be lost during cell division. As with duplications, deletions can affect gene dosage and thus the resulting phenotype. Also, the larger the deletion, the more genes are likely to be involved, and the more drastic the resulting defect is likely to be.