Definitive laceration management depends. on the time since injury, the extent and loca-. tion of the wound, available laceration repair. materials, and the skill of the physician. Guidelines for seeking surgical consultation. for laceration repair are presented in Table 1. The optimal time interval from injury to. laceration repair is not clearly defined. Ana-. tomic location of the wound, health of the. patient, mechanism of injury, and wound.
This gene on chromosome 2 codes for the enzyme lactase. This enzyme enables infants to break down lactose, the main sugar in milk. In people who are lactose tolerant, the gene remains active throughout their lives.In most people who are lactose intolerant, the gene is turned off after infancy, making the digestion of dairy products difficult and painful.his enzyme enables infants to break down lactose, the main sugar in milk. In people who are lactose tolerant, the gene remains active throughout their lives. In most people who are lactose intolerant, the gene is turned off after infancy, making the digestion of dairy products difficult and painful.
lactose intolerance-caused by mutations in the LCT gene. At least nine LCT gene mutations cause congenital lactase deficiency, also called congenital alactasia. In this disorder, infants are unable to break down lactose (lactose intolerance) in breast milk or formula.The LCT gene mutations change single protein building blocks (amino acids) in the lactase enzyme or result in an enzyme that is abnormally short.he mutations are believed to interfere with the function of the lactase enzyme, leading to undigested lactose in the small intestine and causing severe diarrhea. Lactose intolerance in adulthood is caused by gradually decreasing activity (expression) of the LCT gene after infancy, which occurs in most humans.