Social exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.It is a term used widely in Europe, and was first used in France. It is used across disciplines including education, sociology, psychology, politics and economics.ocial exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is thought to be caused by trauma to dentoalveolar structures that have a limited capacity for bone healing due to the effects of bisphosphonate therapy. See the image below. Exposed, necrotic bone in the left anterior maxilla.
Zometa is another bisphosphonate. How it works: Bisphosphonates limit the activity of certain bone cells, called osteoclasts, which help cause the bone weakening and damage that can happen when breast cancer spreads to the bone. Bisphosphonates also can help keep blood calcium levels normal.