In patients with connective tissue diseases, it is common for collagen and elastin to become injured by inflammation. Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity).Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases. connective tissue disease is any disease that has the connective tissues of the body as a primary target of pathology. The connective tissues are the structural portions of our body that essentially hold the cells of the body together.
One of the Middle Colonies, New Jersey started out as a Proprietary colony but in 1702 it was granted a Royal charter. New Jersey, in 1787, was the third state to ratify the Constitution. (1624) New York (originally New Amsterdam) [Homepage, Constitution]
Control political power. 13 Colonies Massachusetts, New Hampshire, Connecticut, Rhode Island, New York, Pennsylvania, New Jersey, Delaware, Maryland, Virginia, North Carolina, South Carolina, Georgia Colonial Regions New England, Middle, and Southern New England Colonies Commerce and Religion Massachusetts, New Hampshire, Connecticut, Rhode Island Settled by Pilgrims, Puritans, and other Protestant religious groups; mostly from England.