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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
There are 2 main types of glaucoma laser treatments that are used to widen the anterior chamber drainage angle for angle closure glaucoma: YAG laser peripheral iridotomy and argon laser peripheral iridoplasty.