Patients with chronic hepatitis B have antibodies against hepatitis B, but these antibodies are not enough to clear the infection of the affected liver cells. The continued production of virus combined with antibodies is a likely cause of the immune complex disease seen in these patients.
1 Hydrolytic Degradation: ï This process occurs in polymers that are watersensitive active groups, especially those that take a lot of moisture. ï 2  Polymers that have an ability for hydrolytic destruction usually have heteroatoms in the main or side chain. Mechanism of Hydrolytic Degradation ï Hydrolytic degradation of members of the polylactide/glycolide family proceeds through four stages as represented in Figure 2: First stage of water diffusion followed by second stage, in which oligomers with acidic endgroups autocatalyze the hydrolysis reaction.
Usually hydrolysis is a chemical process in which a molecule of water is added to a substance. Sometimes this addition causes both substance and water molecule to split into two parts.In such reactions, one fragment of the target molecule (or parent molecule) gains a hydrogen ion.trong acids also undergo hydrolysis. For example, dissolving sulfuric acid (H 2 SO 4) in water is accompanied by hydrolysis to give hydronium and bisulfate, the sulfuric acid's conjugate base. For a more technical discussion of what occurs during such a hydrolysis, see BroenstedâBrÃ¸nsted lowryâacid base. theory