1 For patients not covered by health insurance, a prostate cancer test typically costs from less than $15-$250 for a digital rectal exam to detect any physical abnormalities in the prostate, depending on the provider and whether the exam is done on its own or as part of an office visit. And it can cost up to $6,000 or more for a prostate biopsy. 2  For example, several cancer centers in Michigan offer prostate exams for $15-$20. 3  Talbert Medical in California, charges about $60. 4  And Robert Gluck, M.D, a urologist in New York, charges $250 for an office visit that includes a digital prostate exam.
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