Not Now. Established in 1989, the Clearwater Volunteer Fire Department serves the Clearwater (Tennessee) community and surrounding area with support. 1,185 people like this and 1,166 people follow this.
Pathologic changes in chronic obstructive pulmonary disease (COPD) occur in the large (central) airways, the small (peripheral) bronchioles, and the lung parenchyma. Most cases of COPD are the result of exposure to noxious stimuli, most often cigarette smoke.
It destroys lung tissue, which results in the obstruction of air flow, and it causes inflammation and irritation of airways that can add to air flow obstruction. 1  Destruction of lung tissue occurs in several ways.