A collection of particular persons or items, formed into one body; as a corporation aggregate, which is one formed of a number of natural persons; the union of individual charges make an aggregate charge.
3. Pleiotropy (or pliotropy) is the phenomenon in which a single gene conditions several different phenotypical traits. Some phenotypical traits may be sensitive to the pleiotropic effects (for example, inhibition) of other genes, even when conditioned by a pair of alleles in simple dominance.A mixture of pleiotropy and gene interaction is characteristic of these cases.1  Non-Mendelian Inheritance-Image Diversity: pleiotropy.ome phenotypical traits may be sensitive to the pleiotropic effects (for example, inhibition) of other genes, even when conditioned by a pair of alleles in simple dominance. A mixture of pleiotropy and gene interaction is characteristic of these cases. 1  Non-Mendelian Inheritance-Image Diversity: pleiotropy.
Amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis, or ALS, is a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement. ALS is also known as Lou Gehrig's disease. 1 out of 10 cases of ALS are due to a genetic defect. The cause is unknown in most other cases. In ALS, motor nerve cells (neurons) waste away or die, and can no longer send messages to muscles. This eventually leads to muscle weakening, twitching, and an inability to move the arms, legs, and body.