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An example of a medicinal enzyme inhibitor is sildenafil (Viagra), a common treatment for male erectile dysfunction. Drugs also are used to inhibit enzymes needed for the survival of pathogens. For example, bacteria are surrounded by a thick cell wall made of a net-like polymer called peptidoglycan.
A competitive inhibitor is a molecule that is structurally similar to the natural substrate of an enzyme such that it is capable of binding to the active site. The small molecule is also assumed to be catalytically inactive, that is, it is not transformed into any product.