Evidence for the use of low frequency ultrasound to treat wounds is limited and consists of studies that lack adequate. sample sizes and proper control groups. Additional research with larger trials is needed to demonstrate that low. frequency ultrasound is beneficial for health outcomes in patients with wounds.
The neurotransmitter, acetylcholine, once it has diffused into the synapse, binds to the nicotinic acetylcholine receptors, which are found in the motor end plate. These receptors are ligand-gated ion channels, and once acetylcholine has binded to the receptors, it causes the channels to open.
Due to crossover of affinities of certain compounds for muscarinic and nicotinic acetylcholine receptors, the compounds were evaluated for binding to muscarinic receptors labeled by [3H]oxotremorine-M, an agonist, and [3H]quinu- clidinyl benzilate, an antagonist.