VOA-Sparrow Clinic The VOA-Sparrow Clinic is a collaboration between Volunteers of America and Sparrow Hospital, providing both physical and mental health care to the homeless in the Lansing area. Their location is 430 N Larch in Lansing.
Answers. Best Answer: Proposed to be an element by Carl Wilhelm Scheele in 1774, manganese was discovered by Johan Gottlieb Gahn, a Swedish chemist, by heating the mineral pyrolusite (MnO2) in the presence of charcoal later that year.
1. Manganese (Mn) is an essential trace element that is found in varying amounts in all tissues. Manganese concentrations are highest in tissues rich in mitochondria, where it forms stable complexes with ATP and inorganic phosphate. Manganese functions as a constituent of metalloenzymes and an activator of enzymes. key neurochemical alteration associated with manganese neurotoxicity is altered extracellular glutamate levels. Attenuated glutamate uptake by astrocytes has been invoked as the primary cause for this disturbance (Hazell and Norenberg, 1997 and Erikson and Aschner, 2002).