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Antipsychotic Medications. Antipsychotic medications are the main form of treatment for psychotic disorders, not just for the treatment of schizophrenia. They are also called neuroleptic drugs or neuroleptics.Antipsychotic medications first came into recognition in the 1950s when it was fortuatously first used as an anxiolytic for the treatment of delirium. It was noticed that it had a very calming effect and that psychotic symptoms also improved.n scientific terms, they are called antogonists-they antagonise the action of dopamine. Drugs which attach to receptors and promote the action of the receptor are called agonists. Drugs can also be judged by the degree of potency of the action at the receptor.
The 1990s saw the development of several new drugs for schizophrenia, called atypical antipsychotics.. Because they have fewer side effects than the older drugs, today they are often used as a first-line treatment. The first atypical antipsychotic, clozapine (Clozaril), was introduced in the United States in 1990.ntipsychotic medications act against these symptoms. These medications cannot cure the illness, but they can take away many of the symptoms or make them milder. In some cases, they can shorten the course of an episode of the illness as well. There are a number of antipsychotic (neuroleptic) medications available.