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lipoprotein lipase (LPL), an enzyme that plays a key role in breaking down triglycerides present in chylomicrons and very low-density lipoprotein particles, releasing their fatty acids for entry into tissue cells.
Normal Function. The APOE gene provides instructions for making a protein called apolipoprotein E. This protein combines with fats (lipids) in the body to form molecules called lipoproteins. Lipoproteins are responsible for packaging cholesterol and other fats and carrying them through the bloodstream.