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Mouth sores may be caused by irritation from: 1  A sharp or broken tooth or poorly fitting dentures. 2  Biting your cheek, tongue, or lip. 3  Burning your mouth from hot food or drinks. 4  Braces. Chewing tobacco.
Several conditions can cause a burning sensation in the mouth. Some nutritional deficiencies â particularly of B vitamins, iron and zinc â can cause it. These problems can be detected by simple blood tests. Medicines that cause the mouth to become dry (due to decreased saliva production) can result in mouth irritation.