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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
In angle-closure glaucoma or in patients at risk for this condition, laser iridotomy is the preferred method of treatment. In treating glaucoma with lasers, it is important to understand what type of glaucoma you may have.