slide 2 of 12. Skin The skin is the largest organ in the human body. Its main job is to maintain the body's temperature, which means that sweat is created to cool the body, and goosebumps or raised hair occur to trap heat in the body. Along with sweat glands, the skin contains oil glands.
...However, if I am wrong about that, the answer is that acetaminophen (and its metabolites) are identifiable for up to 48 hours after you took the pill. Less if you took tiny doses, but up to standard clinical doses (<8g), it's 48ish hours.
Hydrocodone itself does not cause possible liver damage, but the actual acetaminophen in the pill is what can cause liver damage in high doses. Typically one must consume more then 8,000 mg in a 24 hour period consistently over a period of time to cause damage.cetaminophen is processed by the liver and it takes about 4 hours for the liver to break it down. Taking more then the recommended dosage can cause the liver hardship. Granted going over a few times won't necessarily cause permanent damage, but consistent use may.