When a reaction occurs at the site of a vesicant injection (e.g., in patients receiving cancer chemotherapy), close monitoring by a physician or the injection of local antidotes may be required. Reactions that result in infection or necrosis may need to be treated with antibiotics or with surgical dÃ©bridement.
Cortisone cream is a topical corticosteroid ointment that reduces inflammation to areas where applied. It is often used to topically treat arthritis pain from inflammation of the joints, as well as inflammation of the skin caused by various skin disorders and conditions. Available in over-the-counter strength, it is usually sold as hydrocortisone.
1 Cortisone injections can offer fast-acting relief of inflamed muscles, joints, tendons, and bursa. 2  Complications are rare but may include infection and bleeding.  When administered by an expert, cortisone injections offer significant pain relief with only minimal discomfort.