FDD Talk 2013: Average Pricing, Hourly Costs and Gross Revenues for College Nannies and Tutors Businesses (2013 FDD) Highlights of College Nannies and Tutorsâ Item 19 Financial Performance Representations (2013 FDD) â Part 1. Explanatory Note for Section 1. The franchisor has prepared six charts which are included in Section 1 below using current pricing and expense information from actual College Nannies and Tutors franchised businesses.
TUESDAY, July 7, 2015 (HealthDay News) -- The U.S. Food and Drug Administration on Tuesday approved the drug Entresto (sacubitril/valsartan) to treat heart failure. Characterized by the heart's inability to pump enough blood, the progressive disease affects some 5.1 million people in the United States.
Mechanism of Action. Entresto is a combination of sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin II receptor blocker. Entresto inhibits neprilysin (neutral endopeptidase; NEP) via LBQ657, the active metabolite of the prodrug sacubitril, and blocks the angiotensin II type-1 (AT1) receptor via valsartan.