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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
Forskolin appears to work in a way similar to certain types of conventional asthma drugs, by boosting the levels of a compound called cyclic AMP. This helps relax the muscles around the bronchial tubes to make breathing easier. Forskolin has also been used to try to treat glaucoma. But there is no proof that it works.