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Inflammatory bowel disease (IBD) is a condition that involves chronic inflammation in all or part of the digestive tract. Often painful and debilitating, IBD can lead to life-threatening complications as well as increase the risk for colon cancer.hough Crohn's can affect any of the digestive tract, it most commonly affects the end of the small bowel (the ileum) and the beginning of the colon. With Crohnâs disease, the inflammation causes swelling and scar tissue to thicken the intestinal wall.
It's not clear what causes the inflammation of the colon found in microscopic colitis. Researchers believe that the causes may include: Medications that can irritate the lining of the colon. Bacteria that produce toxins that irritate the lining of the colon. Viruses that trigger inflammation.