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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
Why It Is Done. Laser iridotomy is mainly used to: 1  Treat closed-angle glaucoma after the pressure in the affected eye has been reduced with medicine or when medicines fail. 2  Prevent closed-angle glaucoma in people who have narrow drainage angles and those people who have had closed-angle glaucoma in their other eye.aser Iridotomy for Glaucoma. Guide. Laser iridotomy uses a very focused beam of light to create a hole on the outer edge, or rim, of the iris, the colored part of the eye.