Body aches or pains, Fatigue, Joint aches and Joint pain. WebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms body aches or pains, fatigue, joint aches and joint pain including Viral syndrome, Exercise or physical activity, and Lyme disease.ebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms body aches or pains, fatigue, joint aches and joint pain including Viral syndrome, Exercise or physical activity, and Lyme disease.
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They have a long history of use as medications prescribed for the treatment of depression. They are particularly effective in treating atypical depression.
Perhaps importantly, monoamine oxidase B (MAO-B) is located in the mitochondrial wall and plays a significant role in dopamine degradation in PD. This can explain the symptomatic actions of MAO-B inhibitors, such as selegiline and rasagiline on motor symptoms of PD.n this brief review, the role played by mitochondria is examined and in turn, how monoamine oxidase B (MAO-B) located in the inner mitochondrial wall might be a target for modifying cell death in PD through the use of selective MAO-B inhibitors.