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A new understand is now emerging that greater health benefits of melatonin supplementation are associated with increased duration of REM and deep sleep, crucial for nightly repair, regeneration and detoxification. Beyond sleep, research (over 6000 studies) shows that melatonin benefits are profound and far reaching. Known as the bodyâs most efficient free-radical scavenger with an impressive ability to control oxidative damage, melatonin has powerful antioxidant, anti-inflammatory and immune properties.
In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythms of physiological functions including sleep timing, blood pressure regulation, seasonal reproduction and many others.any of melatonin's biological effects in animals are produced through activation of melatonin receptors, while others are due to its role as a pervasive and powerful antioxidant, with a particular role in the protection of nuclear and mitochondrial DNA.