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A female should be retired from breeding at the age of 7 years maximum. A female Yorkie may need to be retired much younger and this will depend on the recommendation of an experienced and trusted veterinarian who makes a determination after evaluating the individual dog's health and history.
You want to start breeding does (female rabbits) when they are reaching maturity. For small-medium breeds, they can be bred at 5-6 months old. Larger breeds can be bred at 8-9 months. Bucks (male rabbits) are usually ready around 6 months old if a small breed, 7 months if medium, and 9 months for a large breed.