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Monoclonal antibodies are laboratory-produced molecules engineered to serve as substitute antibodies that can restore, enhance or mimic the immune system's attack on cancer cells. They are designed to bind to antigens that are generally more numerous on the surface of cancer cells than healthy cells.
The three groups of heterophile antibodies are polyspecific antibodies, antiimmunoglobulin antibodies, and high-specificity high-affinity antibodies against antigens from animal species. In clinical practice, the most important significance of heterophile antibodies is their use in diagnosing infectious mononucleosis.