World Weather & Climate Information. Average monthly weather in Adelaide, Australia. Adelaide generally has mild, wet winters and warm, dry summers. It is the driest of all the Australian capital cities. In summer (December to February) the average maximum is around 29 degrees Celsius (84 Â°Fahrenheit), but there is considerable variation.
Cohesin is a protein complex that regulates the separation of sister chromatids during cell division, either mitosis or meiosis. Cohesins hold sister chromatids together after DNA replication until anaphase when removal of cohesin leads to separation of sister chromatids.
The amino and carboxy terminus of Scc1 bind Smc1 and Smc3. Once Scc1 binds the SMC proteins, Scc3 can also associate by binding with the C-terminal region of Scc1. When Scc1 binds on both Smc1 and Smc3, the cohesin complex forms a closed ring structure. When it binds to only one of the SMC proteins, the complex forms an open ring. Early studies suggested various ways in which cohesin may entrap DNA, including as a monomer that holds both homologues together, and a hand-cuff model where two intertwining cohesin complexes each hold one sister chromatid.