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Hand numbness is usually caused by damage, irritation or compression of one of the nerves or a branch of one of the nerves in your arm and wrist. Diseases affecting the peripheral nerves, such as diabetes, also can cause numbness, although with diabetes similar symptoms usually occur first in your feet. In very uncommon instances, numbness can be caused by problems in your brain or spinal cord, although in such cases arm or hand weakness or loss of function also occurs. Numbness alone is only rarely associated with potentially life-threatening disorders, such as strokes or tumors.
Bursitis, or inflammation of a bursa sac, can develop at either of these locations. Nerves travel from the spine to the fingertips, giving sensation to the skin along the way. Compression of these nerves as they arise from the spine or along their route through the neck and arm can cause tingling in the arm and hand.