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Canker sores are thought to be caused by: 1  Injuries to the mouth, as seen frequently by contact sports players. 2  Temperature hot food or drink may cause a canker sore in the area of the mouth that was essentially burnt by the offending substance.
No one knows what causes these small, painful blisters inside your mouth. Triggers include injury, hypersensitivity, infection, hormones, stress and not getting enough of some vitamins. Also called aphthous ulcers, mouth ulcers can appear on your tongue, cheek and gums. They usually last a week or two. Mouth ulcers can be treated with numbing gels.