The strength of selection is measured by the selective effect, s, of a single gene and the strength of random genetic drift is indicated by (1/2Ne), where the population has effective size, Ne. When s exceeds (1/2Ne), then the evolutionary fate of a gene is determined primarily by Natural Selection.
Voltaren Gel (diclofenac sodium topical gel) is a topical gel nonsteroidal anti-inflammatory drug (NSAID) used to treat pain of osteoarthritis of joints that are amenable to topical treatment, such the hands and knees.
5 - Since Voltaren Gel is an NSAID, it carries the same cardiovascular risks. As with all NSAIDs, there may be an increased risk of serious or possibly fatal cardiovascular events, heart attack, or stroke with the use of Voltaren Gel. Despite the fact that the risk is less than with oral NSAIDS, there still is a risk.