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NOPAT is precisely calculated as: NOPAT = (Net Income-after-tax Non-operating Gains + after-tax Non-operating Losses + after-tax Interest Expense). NOPAT doesnât include one-time losses and other non-recurring charges because they donât represent the true, on-going profitability of the business.OPAT is used by analysts and investors as a precise and accurate measurement of profitability to compare a company's financial results across its history and against competitors.