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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
The standard dosage of mitomycin ophthalmic for use during glaucoma surgery is one vial (0.2 mg) dissolved in 1 mL of sterile water, applied topically to the surgical site. The medication is not injected into the eye.