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This would include people with hypertension (high blood pressure), and heart rhythm irregularities. Mucinex does not elevate the blood pressure, cause the jitters, or cause palpitations like the pseudephedrine containing medications do.
Different blood pressure medications have different side effects. Calcium channel blockers are used to lower blood pressure, and the biggest side effect is having some edema or swelling. There are medications that may affect the kidneys. There are medications that slow the heart rate down and may make you a little bit tired or fatigued. However, without medication, the biggest side effect of hypertension is a stroke. Other negative effects of high blood pressure include heart failure, heart attack and kidney failure.