A collection of particular persons or items, formed into one body; as a corporation aggregate, which is one formed of a number of natural persons; the union of individual charges make an aggregate charge.
Pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits. The underlying mechanism is that the gene codes for a product that is, for example, used by various cells, or has a signaling function on various targets.A classic example of pleiotropy is the human disease phenylketonuria (PKU).nsourced material may be challenged and removed. (September 2013). Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits, an example being phenylketonuria, which is a human disease that affects multiple systems but is caused by one gene defect.
Atrophy. Definition: Decrease in the size of cells, tissues, or organs. Causes of atrophy include poor nourishment, poor circulation, loss of hormonal support, loss of nerve supply to the target organ, disuse or lack of exercise, or disease intrinsic to the tissue itself.Hormonal and nerve inputs that maintain an organ or body part are referred to as trophic.Atrophy is a general physiological process of reabsorption and breakdown of tissues, involving apoptosis on a cellular level. It can be part of normal body development and homeostatic processes, or as a result of disease.ormonal and nerve inputs that maintain an organ or body part are referred to as trophic. Atrophy is a general physiological process of reabsorption and breakdown of tissues, involving apoptosis on a cellular level. It can be part of normal body development and homeostatic processes, or as a result of disease.