Also, they determined that when the spleen reached or extended below the lower third of the left kidney, this was highly specific for splenomegaly despite a low sensitivity (sensitivity 20%, specificity 93%). The study validated the use of a simple splenic length measurement for splenic CT volume. When splenic length exceeds 10 cm, a diagnosis of splenomegaly should be made. This clinically practical, accurate, simple measurement replaces multiple-measurement, time-consuming methods, and allows daily routine follow-up, the authors reported.
1 This volume will in addition discuss RNA viruses and bring a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses.  This volume will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.
1 Certain genetic disorders, such as Down syndrome, are associated with an increased risk of leukemia. 2  Exposure to certain chemicals. 3  Exposure to certain chemicals, such as benzene â which is found in gasoline and is used by the chemical industry â also is linked to an increased risk of some kinds of leukemia. 4  Smoking. Previous cancer treatment. 2  People who've had certain types of chemotherapy and radiation therapy for other cancers have an increased risk of developing certain types of leukemia. 3  Genetic disorders. 4  Genetic abnormalities seem to play a role in the development of leukemia.