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Quick Answer. In a psychological context, labile mood refers to a mood state in which a person experiences wild, uncontrolled mood swings. Labile mood is also known as labile affect, emotional dysregulation and pseudobulbar affect.
Medical Definition of labile. : readily or frequently changing: asa: readily or continually undergoing chemical, physical, or biological change or breakdown a labile antigenb: characterized by wide fluctuations (as in blood pressure or glucose tolerance) labile hypertension labile diabetesc: emotionally unstable.