Its competitor, Otrexup, costs $500 to $600 a month for a 25 mg dose â more than a vial of methotrexate and far more than pills, which cost $20 to $30 for a dozen 2.5 mg tablets.
The leaders of Britain, France, Italy, and Germany held a conference in Munich, Germany, on September 29-30, 1938, in which they agreed to the German annexation of the Sudetenland in exchange for a pledge of peace from Hitler. Czechoslovakia, which was not a party to the Munich negotiations, agreed under significant pressure from Britain and France. On March 15, 1939, Hitler violated the Munich agreement and moved against the Czechoslovak state. The Czech provinces of Bohemia and Moravia were proclaimed a German protectorate and were occupied by German forces. Slovakia became an independent state, closely allied with Germany.
A+E Networks. Nazi leader Adolf Hitler violates the Treaty of Versailles and the Locarno Pact by sending German military forces into the Rhineland, a demilitarized zone along the Rhine River in western Germany.n 1935, Hitler unilaterally canceled the military clauses of the treaty and in March 1936 denounced the Locarno Pact and began remilitarizing of the Rhineland.