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Phenylalanine has been around as long as life itself, if not longer. It's not something that someone invented one day. It's like oxygen: no one invented it, it's been here as long as anyone can remember, and far longer! J. Heinrich Matthaei and Marshall W. Nirenberg figured out a way to make a bacterium produce long chains of phenylalanine molecules in 1961.
Article Sections. The blood sample for phenylketonuria (PKU) screening should be obtained at least 12 hours after the infant's birth. Newborn screening for PKU has largely eliminated mental retardation caused by this disease. If the first phenylalanine test demonstrates positive results, a repeat test should be performed. Treatment to prevent sequelae from this disorder is best carried out in cooperation with an experienced PKU center.