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It is painful when the organs stop working. That is why the key to a relatively peaceful death is pain killers. I saw my grandfather die. He too had Alzheimer's and was a very moral and good man. However, as his body shut down and his organs failed, no amount of his good deeds on earth could ameliorate his pain.t is a release. There may be pain associated with the cause of death, depending upon the cause. But death itself is a painless letting go. At the time of death the body produces endorphins which actually produce a feeling of happiness, or even euphoria.
At the same time, without circulation to keep it moving through the body, blood starts to pool and settle. Rigor mortis, or a stiffening of the body, sets in about two to six hours after death [source: Marchant, Middleton ]. While the body as a whole may be dead, little things within the body are still alive. Skin cells, for example, can be viably harvested for up to 24 hours after death [source: Mims ].