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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
A recent advance in ophthalmology is the use of the SLT laser as a first line of defense and an alternative to eye drops in treating glaucoma. SLT laser has been clinically proven to treat glaucoma by safely and effectively reducing intraocular pressure in a brief office procedure that is covered by Medicare!