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Isocrates was an influential teacher, perhaps the most so in the ancient history of rhetoric. His students included many notable citizen statesmen and decorated leaders. Isocrates' school had entrance requirements (few others did in those days--other than the requisite tuition).
Miletus was the native city of Thales, Anaximander and Anaximenes; Colophon of Xenophanes; Ephesus of Heraclitus; Samos of Pythagoras and Melissus; Elea of Parmenides and Zeno; Sicily of Empedocles; Clazomenes of Anaxagoras; Abdera of Leucippus and Democritus. The Presocratic philosophy is a philosophy of nature.