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Breast Cancer 101 (Interactive Multimedia) - Surgical Biopsy. Macromedia Flash. A surgical biopsy is the most accurate way to diagnose breast cancer and get complete information about the tumor. However, it is more invasive than a needle biopsy.Because core needle biopsy is accurate in diagnosing cancer and does not involve surgery, it is often the preferred biopsy method [ 3,5 ].n most surgical biopsies, the entire suspicious area plus some of the surrounding normal tissue is removed from the breast (excisional biopsy).
Core needle biopsy. This process is very similar to a fine needle biopsy, but the size of the needle used in a core needle biopsy is larger. The larger needle is used to extract a cylinder of tissue, which provides more tissue for the pathologist to analyze. Vacuum-assisted biopsy.