NSAIDs work by reducing the production of prostaglandins, chemicals that cause pain, fever and inflammation. NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower production of prostaglandins. As a consequence, inflammation, pain and fever are reduced.
Medical Definition of BILIRUBIN. : a reddish yellow pigment C33H36N4O6 that occurs especially in bile and blood and causes jaundice if accumulated in excess.
Bilirubin that is bound to a certain protein is called unconjugated, or indirect, bilirubin. Conjugated, or direct, bilirubin travels freely through your bloodstream to your liver. Most of this bilirubin passes into the small intestine, but a very small amount passes into your kidneys and is excreted in your urine.ilirubin is a substance made when your body breaks down old red blood cells, a normal process. Bilirubin is also part of bile, which your liver makes to help digest the food you eat. A small amount of bilirubin in your blood is normal. Healthy adults produce 250 to 350 milligrams (mg) of bilirubin each day.