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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
Evidence for effectiveness of citalopram for treating depression in children is uncertain. Citalopram is licensed in the UK and other European countries for panic disorder, with or without agoraphobia. The dose is 10 mg/d for a week, increasing to 20â30 mg/d, with a maximum of 40 mg/d.