Its competitor, Otrexup, costs $500 to $600 a month for a 25 mg dose â more than a vial of methotrexate and far more than pills, which cost $20 to $30 for a dozen 2.5 mg tablets.
The leaders of Britain, France, Italy, and Germany held a conference in Munich, Germany, on September 29-30, 1938, in which they agreed to the German annexation of the Sudetenland in exchange for a pledge of peace from Hitler. Czechoslovakia, which was not a party to the Munich negotiations, agreed under significant pressure from Britain and France. On March 15, 1939, Hitler violated the Munich agreement and moved against the Czechoslovak state. The Czech provinces of Bohemia and Moravia were proclaimed a German protectorate and were occupied by German forces. Slovakia became an independent state, closely allied with Germany.
Emboldened by Great Britain and France's reaction to the Rhineland, Hitler began to move forward with a plan to unite all German-speaking peoples under one Greater German regime. Again operating in violation of the Treaty of Versailles, Hitler made overtures regarding the annexation of Austria. While these were generally rebuffed by the government in Vienna, Hitler was able to orchestrate a coup by the Austrian Nazi Party on March 11, 1938, one day before a planned plebiscite on the issue.