Social exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.It is a term used widely in Europe, and was first used in France. It is used across disciplines including education, sociology, psychology, politics and economics.ocial exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is thought to be caused by trauma to dentoalveolar structures that have a limited capacity for bone healing due to the effects of bisphosphonate therapy. See the image below. Exposed, necrotic bone in the left anterior maxilla.
Osteonecrosis of the Jaw. Osteonecrosis of the jaw (ONJ) may occur in patients taking strong antiresorptive medications such as bisphosphonates or RANKL inhibitors. ONJ has not been reported with other antiresorptive therapies such as SERMs or calcitonin. SERMs include therapies like raloxifene (Evista).