Using the process flowchart, label each component with a sequential reference number. 1  These reference numbers will be used throughout the FMEA process. 2  The marked-up flowchart will give you a powerful visual to refer to throughout the PFMEA.
Although vitamin D deficiency rickets is rare in the United States, children who are dark skinned and living in cloudy northern cities as well as children on restricted diets due to cultural or religious beliefs are more likely to develop this disorder.
Rickets and osteomalacia are the classical vitamin D deficiency diseases. In children, vitamin D deficiency causes rickets, a disease characterized by a failure of bone tissue to properly mineralize, resulting in soft bones and skeletal deformities [ 17 ].Rickets was first described in the mid-17th century by British researchers [ 17, 26 ].n children, vitamin D deficiency causes rickets, a disease characterized by a failure of bone tissue to properly mineralize, resulting in soft bones and skeletal deformities [ 17 ]. Rickets was first described in the mid-17th century by British researchers [ 17, 26 ].