  Although the terms ocean and sea are often used interchangeably, a sea is generally considered to be smaller than an ocean. One definition of ocean is: a great bod â¦ y of interconnecting salt water that covers 71 percent of the Earth's surface.
Sharpie brand permanent markers. A permanent marker or indelible marker is a type of marker pen that is used to create permanent writing on an object. In general, the ink comprises a main carrier solvent, a glyceride, a pyrrolidone, a resin and a colorant, making it waterproof.
A high level of the marker may indicate a worsened prognosis in some situations. The most effective and common purpose of tumor markers is to monitor the cancer treatment. As the cancer levels go on decreasing in the body, the marker also goes down. If the marker remains stagnant or increases, it is usually an indication that the patient is not responding sufficiently to the treatment.