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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
Laser surgery treatments may be effective for different types of glaucoma. The laser is usually used in one of two ways. In open-angle glaucoma, the drain itself is treated. The laser is used to enlarge the drain (trabeculoplasty) to help control eye pressure.