Normal RAS signalling pathways. RAS proteins: diversity and processing. The RAS proteins are members of a large superfamily of low-molecular-weight GTP-binding proteins, which can be divided into several families according to the degree of sequence conservation.
Microsoft originally marketed a spreadsheet program called Multiplan in 1982, which was very popular on CP/M systems, but on MS-DOS systems it lost popularity to Lotus 1-2-3. This promoted development of a new spreadsheet called Excel which started with the intention to 'do everything 1-2-3 does and do it better'. The first version of Excel was released for the Mac in 1985 and the first Windows version was released in November 1987. Lotus was slow to bring 1-2-3 to Windows and by 1988 Excel had started to outsell 1-2-3 and helped Microsoft achieve the position of leading PC software developer.
I assume you're asking what the first commercially available video game was. That would be Computer Space, an arcade game that was released in 1971. The first home console â¦ was the Magnavox Odyssey, released early in 1972. Atari's Pong, which many believe to be the first video game, was also released as an arcade game in 1972, although the home consoles weren't made available until '75. 1 person found this useful.