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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
How to use brinzolamide eye drops. 1  Wash your hands well before you use the drops. 2  Remove the cap. 3  Tilt your head back a little and pull the lower lid of your eye out to form a pocket.  Hold the bottle upside down near to your 1  eye. Apply enough pressure to the base of the bottle to release one drop into your  eye.