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A female should be retired from breeding at the age of 7 years maximum. A female Yorkie may need to be retired much younger and this will depend on the recommendation of an experienced and trusted veterinarian who makes a determination after evaluating the individual dog's health and history.
The Bulldog is, at best, difficult to breed. Bitches can come into there first heat cycle from 5 to 11 months of age, on average it is more in the 6-9 month range. They should not be breed before there 3rd heat or 18 months.