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lipoprotein lipase (LPL), an enzyme that plays a key role in breaking down triglycerides present in chylomicrons and very low-density lipoprotein particles, releasing their fatty acids for entry into tissue cells.
Lipoproteins transport lipids in the circulation in four major pathways: (i) a postprandial (exogenous) pathway for chylomicrons; (it) an endogenous pathway involving very-low-density lipoprotein (VLDL) for triglyceride (TG) transport from the liver; (iii) a low-density lipoprotein (LDL) pathway from a proportion of VLDL as a source of cholesterol for cells; and (iv) a reverse cholesterol transport pathway by high-density lipoprotein (HDL).