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On each side of the opening to the vagina, there is a Bartholin gland. These glands produce fluid to lubricate the opening to the vagina. If a Bartholin gland duct becomes blocked, fluid builds up inside the gland, causing a cyst. ByHealthwise Staff. Primary Medical ReviewerSarah Marshall, MD - Family Medicine.
Experts believe that the cause of a Bartholin's cyst is a backup of fluid. Fluid may accumulate when the opening of the gland (duct) becomes obstructed, perhaps caused by infection or injury. A Bartholin's cyst can become infected, forming an abscess.