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ALT is normally found inside liver cells. However, when the liver is damaged or inflamed, ALT can be released into your bloodstream. This causes serum ALT levels to rise. Measuring the level of ALT in the blood can help doctors evaluate liver function or determine the underlying cause of a liver problem. The ALT test is often part of an initial screening for liver disease. An ALT test is also known as a serum glutamic pyruvic transaminase (SGPT) test or an alanine transaminase test.
ALT is an enzyme found primarily in the liver that helps your body metabolize protein. ALT levels in the blood are normally low. Levels increase when the liver is damaged and ALT is released into the bloodstream. AST is an enzyme that helps with the metabolism of alanine, an amino acid. AST is normally found in high concentrations but an increase in AST levels may also indicate liver damage or disease.