Toradol (ketorolac): Was given an im injection in the buttocks for migraines and it was completely ineffective. The pain that the injection caused was infuriating considering there was absolutely no relief of the headache..
Examples of full agonists are oxycodone, methadone, codeine, heroin and morphine. PARTIAL AGONISTS. Partial agonists are drugs that bind primarily to mu opioid receptors and cause them to produce endorphins but to a much lesser extent than full agonists. BuprenorphineÂ®, SuboxoneÂ® and SubutexÂ® are partial agonists.
Codeine is a weak analgesic widely used in the management of mild-to-moderate pain. Morphine, the product of codeine O-demethylation by the highly polymorphic enzyme cytochrome P450 2D6 (CYP2D6), is the metabolite primarily responsible for the analgesic effect of codeine.