Membranes contain large amounts of lipids, which are notoriously hydrophobic (water and oil don't mix). The membrane-spanning regions of membrane proteins are typically alpha helices, made of hydrophobic amino acids.
Florence, for example, hosted a brilliant period of musico-theatrical innovation at the dawn of the seventeenth century that led to the flowering of early opera. Rome continued to influence sacred music and for a time became an important center of opera, several types of vocal chamber music, and instrumental music. Venice, a leading musical city throughout the seventeenth century, nurtured the development of opera, as did Naples in the eighteenth century.
THE CLASSICAL PERIOD (1775-1825). The Baroque period culminated in the masterpieces of J.S. Bach and G.F. Handel. In the middle of the eighteenth century, contemporaneous with the mature years of Bach and Handel, a new musical style developed that is known as Rococo or preclassical style.