Historians typically use the title Republican Party. It was the second political party in the United States, and was organized by then Thomas Jefferson and his friend James Madison in 1791â93, to oppose the Federalist Party run by Secretary of the Treasury Alexander Hamilton.
Type 1 diabetes occurs when your immune system, the bodyâs system for fighting infection, attacks and destroys the insulin-producing beta cells of the pancreas. Scientists think type 1 diabetes is caused by genes and environmental factors, such as viruses, that might trigger the disease.
What happens when insulin production and secretion fails? How does the body react to a collapse of the insulin signalling system? This can follow either destruction of Islet beta cells (diabetes type 1) or loss of response to insulin (diabetes type 2/insulin resistance).