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skeleton. 1  the hard framework of an animal body, supporting the tissues and protecting the organs; specif., all the bones collectively, or the bony framework, of a human being or other vertebrate animal. 2  anything like a skeleton in any of various ways a very lean or emaciated person or animal.
bone. 1. a. one of the structures composing the skeleton of a vertebrate. b. the hard connective tissue forming these structures, composed of cells enclosed in a calcified matrix. 2. such a structure from an edible animal, usu.with meat adhering to it, as an article of food: a ham bone.. one of the structures composing the skeleton of a vertebrate. b. the hard connective tissue forming these structures, composed of cells enclosed in a calcified matrix. 2. such a structure from an edible animal, usu. with meat adhering to it, as an article of food: a ham bone.