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The important point is that the surface area to the volume ratio gets smaller as the cell gets larger. Thus, if the cell grows beyond a certain limit, not enough material will be able to cross the membrane fast enough to accommodate the increased cellular volume. When this happens, the cell must divide into smaller cells with favorable surface area/volume ratios, or cease to function. That is why cells are so small.
View Full Document. Why eukaryotic cells can be larger and more complex than prokaryotic cells - This in part, limits how big bacteria can get; bacteria are smaller than a eukaryotic cell - This is explained by an interesting relationship with regards to the size of cells, what constrains how big a cell can get?