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Statins and Liver Damage. Some people may develop liver-related side effects while taking statins. These may include hepatitis, jaundice, or an increase in liver enzymes. Possible symptoms of liver damage may include nausea, stomach pain, and yellowing of the skin or eyes.
But up to 29 percent of the people who start taking statins report muscle pain and many discontinue statins because of it. Many of these people do well when they are switched to a different variety of statin. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million of patients taking statins.