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The symptoms of ankylosing spondylitis are related to inflammation of the spine, joints, and other organs. Fatigue is a common symptom associated with active inflammation. Inflammation of the spine causes pain and stiffness in the low back, upper buttock area, neck, and the remainder of the spine.ther areas of the body affected by ankylosing spondylitis include the eyes, heart, and kidneys. Patients with ankylosing spondylitis can develop inflammation of the iris (iritis), the colored portion of the eye. Iritis is characterized by redness and pain in the eye, especially when looking at bright lights.
Musculoskeletal problems are the most common cause of back pain, but occasionally, back pain can be a symptom of kidney problems. If you are experiencing pain that moves towards your side and groin area, or if you have a fever or urinary symptoms, then your kidneys could be the source.