Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disease and liver cancer. PAs are tumorigenic. Disease associated with consumption of PAs is known as pyrrolizidine alkaloidosis.
The venom is what causes the symptoms. The main symptoms are pain, itching, swelling and redness at the sting site. Severe pain or burning at the site lasts 1 to 2 hours. Itching often follows the pain. Swelling. The bee sting may swell for 48 hours after the sting. The swelling can be small or large.
Picture of Brown Recluse Spider Bites. Brown recluse spider bites often go unnoticed initially because they are usually painless bites. Occasionally, some minor burning that feels like a bee is noticed at the time of the bite. Symptoms usually develop 2-8 hours after a bite. Keep in mind that most bites cause little tissue destruction.