Viral infections. Rabies (hydrophobia) is a fatal viral disease that can affect any mammal, although the close relationship of dogs with humans makes canine rabies a zoonotic concern. Vaccination of dogs for rabies is commonly required by law. Please see the article dog health for information on this disease in dogs.
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Bisoprolol is a beta-blocker.
Metoprolol can aggravate breathing difficulties in patients with asthma, chronic bronchitis, or emphysema. WARNING: In patients with existing slow heart rates (bradycardias) and heart blocks (defects in the electrical conduction of the heart), metoprolol can cause dangerously slow heart rates, and even shock. Metoprolol reduces the force of heart muscle contraction and can aggravate symptoms of heart failure.