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Statins and Liver Damage. Some people may develop liver-related side effects while taking statins. These may include hepatitis, jaundice, or an increase in liver enzymes. Possible symptoms of liver damage may include nausea, stomach pain, and yellowing of the skin or eyes.
The intended effect of statins was a reduction in the occurrence of cardiovascular disease. The number needed to treat for cardiovascular disease over five years was 37 (95% confidence interval 27 to 64) for women and 33 (95% CI 24 to 57) for men. Acute renal failure was a side effect of statins: the number needed to harm was 434 (95% CI 284 to 783) for women and 593 (95% CI 388 to 1070) for men.