Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disease and liver cancer. PAs are tumorigenic. Disease associated with consumption of PAs is known as pyrrolizidine alkaloidosis.
The venom is what causes the symptoms. The main symptoms are pain, itching, swelling and redness at the sting site. Severe pain or burning at the site lasts 1 to 2 hours. Itching often follows the pain. Swelling. The bee sting may swell for 48 hours after the sting. The swelling can be small or large.
Dealing with the rash. If you don't cleanse quickly enough, or your skin is so sensitive that cleansing didn't help, redness and swelling will appear in about 12 to 48 hours. Blisters and itching will follow. For those rare people who react after their very first exposure, the rash appears after seven to 10 days.ealing with the rash. If you don't cleanse quickly enough, or your skin is so sensitive that cleansing didn't help, redness and swelling will appear in about 12 to 48 hours. Blisters and itching will follow. For those rare people who react after their very first exposure, the rash appears after seven to 10 days.