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Quoting this article Efficacy, effectiveness, efficiency, 1  efficacy is the extent to which a drug has the ability to bring about its intended effect under ideal circumstances, such as in a randomised clinical trial. 2  effectiveness is the extent to which a drug achieves its intended effect in the usual clinical setting.
By Dr Ananya Mandal, MD. In medical terms, efficacy refers to the ability of a product to provide a beneficial effect. In the context of healthcare, the efficacy of a product to yield therapeutic benefits is explored.