A comparable pattern of systemic CD4 T cell activation was observed in patients with CIS and MS, although patients with MS had a somewhat higher percentage of CD4 T cells in blood expressing CD26, and more CD4 T cells in CSF expressing CD71, than did CIS patients.
Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein.n genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype. The genetic code stored in DNA is interpreted by gene expression, and the properties of the expression give rise to the organism's phenotype.
To quantify gene expression, the (Cq) for an RNA or DNA from the gene of interest is subtracted from the (Cq) of RNA/DNA from a housekeeping gene in the same sample to normalize for variation in the amount and quality of RNA between different samples.uantifying gene expression by traditional DNA detection methods is unreliable. Detection of mRNA on a Northern blot or PCR products on a gel or Southern blot does not allow precise quantification.