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The important point is that the surface area to the volume ratio gets smaller as the cell gets larger. Thus, if the cell grows beyond a certain limit, not enough material will be able to cross the membrane fast enough to accommodate the increased cellular volume. When this happens, the cell must divide into smaller cells with favorable surface area/volume ratios, or cease to function. That is why cells are so small.
Too many plasma cells can form a tumor in the bone marrow called a myeloma; many tumors are called multiple myeloma. The excess growth of plasma cells interferes with the body's ability to make red blood cells, white blood cells and platelets.