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The resulting stretch of newly synthesized DNA that is associated with this lagging or discontinuous strand is called an Okazaki fragment. Okazaki fragments, as with DNA replication in general, requires RNA priming, which serves as the beginning of an Okazaki fragment.
Difference between Leading strand and Lagging strand. The DNA replication process is generally referred to as discontinuous, because the polymerizing enzyme can add nucleotides only in the 5â-3â direction, synthesis in one strand(leading strand is continuous in the 5â-3â direction towards the fork. In the other strand (lagging strand), as the forks opens, multiple sites of initiation are exposed.