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What is the best time to take Insulin? The best time to take ordinary insulin is 30 minutes before food, so the level of insulin and sugar in the blood after food intake matches . But in case you have eaten already, it is better to take the injection immediately after, rather than not taking.
A American Diabetes Association answered. There are two types of basal insulin people with diabetes could take: - Intermediate-acting insulin (NPH) takes 2 to 4 hours to reach the blood.It works hardest from 4 to 10 hours after your shot and lasts 10 to 16 hours. - Long-acting insulin (Detemir or Glargine) starts working several hours after your shot.here are two types of basal insulin people with diabetes could take: - Intermediate-acting insulin (NPH) takes 2 to 4 hours to reach the blood.