Toradol (ketorolac): Was given an im injection in the buttocks for migraines and it was completely ineffective. The pain that the injection caused was infuriating considering there was absolutely no relief of the headache..
Examples of full agonists are oxycodone, methadone, codeine, heroin and morphine. PARTIAL AGONISTS. Partial agonists are drugs that bind primarily to mu opioid receptors and cause them to produce endorphins but to a much lesser extent than full agonists. BuprenorphineÂ®, SuboxoneÂ® and SubutexÂ® are partial agonists.
Agonists. Agonists bind to and activate receptors in a dose-dependent manner until all opioid receptors are occupied. At this point, the response plateau is reached, and increased doses of agonist have no effect. However, continued use beyond this plateau may lead to respiratory depression and overdose.ntagonists. Antagonists bind to the same receptors as full and partial agonists but do not cause activity at the receptor. Moreover, antagonists block agonists and partial agonists from binding and therefore prevent receptor activation altogether.