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Making the world better, one answer at a time. The amount of time it take for prescription drugs to get out of your system will depend on the type of medicine it is. Antibiotics take about 8 days to leave the body.he amount of time it take for prescription drugs to get out of your system will depend on the type of medicine it is.
About 90% of the drug is eliminated by the kidneys in urine. With a half-life of only 3 hours, 50% of the dosage taken would be eliminated from the body within three hours. However, the remaining dose would not be eliminated for 7 to 10 hours. Sources: