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Quetiapine (/kwÉ¨ËtaÉª.ÉpiËn/ kwi-TY-É-peen) (developed and marketed as Seroquel by AstraZeneca) is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder, and along with an antidepressant to treat major depressive disorder.he sustained-release quetiapine is marketed mainly as Seroquel XR. Other marketing names are Seroquel Prolong, Seroquel Depot and Seroquel XL. On May 18, 2007, AstraZeneca announced that the U.S. FDA approved Seroquel XR for acute treatment of schizophrenia.
1 SEROQUEL XR is approved to work alone to treat 3 types of episodes that may occur in bipolar disorder (depressive lows, manic highs, and mixed episodes of highs and lows), for the short term.  SEROQUEL XR is also approved for long-term maintenance treatment of bipolar I disorder when added to lithium or divalproex.