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a group of substances comprising fatty, greasy, oily and waxy compounds that are insoluble in water and soluble in nonpolar solvents, such as hexane, ether and chloroform. Simple lipids are the triglycerides or neutral fats.ny of a group of organic compounds, including the fats, oils, waxes, sterols, and triglycerides, that are insoluble in water but soluble in common organic solvents, are oily to the touch, and together with carbohydrates and proteins constitute the principal structural material of living cells. lipÂ·idâ²ic adj.
The greater the lipid solubility, the more readily a molecule will pass through the membrane, i.e., the greater will be the flux for a given concentration difference Water soluble, lipid-insoluble substances by definition cannot pass through membranes by dissolving in the lipids.t is called the hydrophilic, or water-loving, portion of the lipid molecule. In contrast, the two tails of each lipid molecule are non-polar and water insoluble. They are composed of long-chain fatty acids which are hydrophobic, or water-hating, in nature.