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Driving distance from Greenville, SC to Columbia, SC. The total driving distance from Greenville, SC to Columbia, SC is 104 miles or 167 kilometers. Your trip begins in Greenville, South Carolina. It ends in Columbia, South Carolina.
There are 193.13 miles from Columbia to Atlanta in west direction and 214.50 miles (345.20 kilometers) by car, following the I-20 route. Columbia and Atlanta are 2 hours 53 mins far apart, if you drive non-stop. This is the fastest route from Columbia, SC to Atlanta, GA. The halfway point is Camak, GA. Columbia, SC and Atlanta, GA are in the same time zone (Eastern Daylight Time).