The lender must document that the existing loan being refinanced is owned (or securitized) by Fannie Mae. Documentation may come from the lenderâs servicing system, the current servicer (if the lender is not the. servicer), from Fannie Maeâs Loan Lookup Tool (https://knowyouroptions.com/loanlookup ) or any other.
Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart (called coronary arteries). Plaque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time.This process is called atherosclerosis.Coronary artery disease (CAD) is the most common type of heart disease in the United States.For some people, the first sign of CAD is a heart attack.laque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time. This process is called atherosclerosis. Coronary artery disease (CAD) is the most common type of heart disease in the United States. For some people, the first sign of CAD is a heart attack.
Atherosclerosis is a big word for a big problem: fatty deposits that can clog arteries. These buildups are called plaque. Theyâre made of cholesterol, fatty substances, cellular waste products, calcium and fibrin (a clotting material in the blood). Sometimes deposits in arteries are compared to a plumbing problem. 1  Think of sludge forming on the inside of pipes. Thatâs not a perfect comparison because buildups donât just form on artery walls but inside them. Still, you get the idea. As plaque builds up, an artery wall gets thicker. This narrows the opening, reducing blood flow and the supply of oxygen to cells. The type of artery affected and where the plaque develops varies with each person. Plaque may partially or totally block blood flow through a large or medium-sized artery in the heart, brain, pelvis, legs, arms or kidneys. When this happens, various diseases may result. These include: coronary heart disease (plaque in arteries in or leading to the heart), angina (chest pain from reduced blood flow in arteries supplying the heart muscle), carotid artery disease (plaque in neck arteries that supply blood to the brain), peripheral artery disease (PAD; plaque in arteries of the extremities, especially the legs) and; chronic kidney disease.