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Ganglion Cyst Quick Overview. A ganglion cyst is a tumor or swelling (benign, not cancerous) usually on top of a joint or the covering of a tendon (tissue that connects muscle to bone). It looks like a sac of liquid (cyst) located just under the skin. Inside the cyst is a thick, sticky, clear, colorless, jellylike material.
ganglion (plural ganglions or ganglia) ( 1 neuroanatomy) An encapsulated collection of nerve-cell bodies, located outside the brain and spinal cord. ( 2 by extension) A centre of intellectual or industrial force, activity, etc. ( 3 pathology) A cystic tumour on a tendon sheath or joint capsule; a ganglion cyst.