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Driving distance from Greenville, SC to Columbia, SC. The total driving distance from Greenville, SC to Columbia, SC is 104 miles or 167 kilometers. Your trip begins in Greenville, South Carolina. It ends in Columbia, South Carolina.
Columbia, SC, USA Summary. Columbia, the capital of South Carolina state (see coordinates for South Carolina), has a latitude of 34Â°0'2.56N and a longitude of 81Â°2'5.33W or 34.00071 and -81.034814 respectively. Based on population, the area is ranked #189 in the United States. Populated areas near Columbia: