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Making the world better, one answer at a time. The amount of time it take for prescription drugs to get out of your system will depend on the type of medicine it is. Antibiotics take about 8 days to leave the body.he amount of time it take for prescription drugs to get out of your system will depend on the type of medicine it is.
How long does it take for Lortab to get out of your system? As explained by Merck, the time needed for a drug to be excreted out of the system is determined by its half-life and the administered dose. According to Drugs.com, a 10/500 mg dose of the pain relief drug Lortab is out of the system within 24 hours after use.