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The major glands of the endocrine system are the pineal gland, pituitary gland, thyroid and parathyroid glands, adrenal glands, pancreas, thymus, ovaries, and testes. There are also other organs in the body that have secondary endocrine functions.These organs include the heart, liver, and kidneys. Hormones can be regulated by other hormones, by glands and organs, and by a negative feedback mechanism. In negative feedback, the initial stimulus is reduced by the response it provokes.he major glands of the endocrine system are the pineal gland, pituitary gland, thyroid and parathyroid glands, adrenal glands, pancreas, thymus, ovaries, and testes. There are also other organs in the body that have secondary endocrine functions.
These hormones also play a role in pregnancy. Although the endocrine glands are the body's main hormone producers, some other organs not in the endocrine system â such as the brain, heart, lungs, kidneys, liver, and skin â also produce and release hormones.nce a hormone is secreted, it travels from the endocrine gland that produced it through the bloodstream to the cells designed to receive its message. These cells are called target cells. Along the way to the target cells, special proteins bind to some of the hormones.