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A host of fractionation procedures are employed by cell biologists. Each organelle has characteristics (size, shape and density for example) which make it different from other organelles within the same cell.
Chromatography is such an important technique that two nobel prizes have been awarded to chromatographers. Over 60% of chemical analysis worldwide is currently done with chromatography or a variation thereon. Chromatography is used in many different ways. Some people use chromatography to find out what is in a solid or a liquid. It is also used to determine what unknown substances are. The Police, F.B.I., and other detectives use chromatography when trying to solve a crime. It is also used to determine the presence of cocaine in urine, alcohol in blood, PCB's in fish, and lead in water. Chromatography is used by many different people in many different ways. Chromatography is based on differential migration. The solutes in