Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disease and liver cancer. PAs are tumorigenic. Disease associated with consumption of PAs is known as pyrrolizidine alkaloidosis.
The venom is what causes the symptoms. The main symptoms are pain, itching, swelling and redness at the sting site. Severe pain or burning at the site lasts 1 to 2 hours. Itching often follows the pain. Swelling. The bee sting may swell for 48 hours after the sting. The swelling can be small or large.
Redness, swelling, itching and pain are all common at the site of the bee sting. There are a few things you can do to try to alleviate the symptoms: Use an ice pack to reduce swelling at the site, but take care not to cause frostbite. Use an antihistamine like diphenhydramine (Benadryl) to reduce swelling and itching.