Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disease and liver cancer. PAs are tumorigenic. Disease associated with consumption of PAs is known as pyrrolizidine alkaloidosis.
The venom is what causes the symptoms. The main symptoms are pain, itching, swelling and redness at the sting site. Severe pain or burning at the site lasts 1 to 2 hours. Itching often follows the pain. Swelling. The bee sting may swell for 48 hours after the sting. The swelling can be small or large.
Usually it takes a few hours for the swelling to go down. If you  have a large local reaction to the stinger, the swelling will  increase for the next 1 or 2 days but will sâ¦ubside after the course  of about a week.