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A: Zyrtec-D is a combination tablet of an antihistamine (Zyrtec) and a decongestant (pseudoephedrine). Antihistamines help with sneezing, runny noses and drainage. Decongestants help relieve pressure and pain in the sinuses. Zyrtec or the antihistamine portion has a potential to cause some drowsiness and dry mouth. Sudafed (pseudoephedrine) can cause difficulty sleeping, nausea, and loss of appetite.
Conclusion on Zyrtec. Never give a dog Zyrtec-D. This strong medication does nothing to address underlying allergies. If your dog has a worsening condition, or is experiencing an acute reaction, get them to a professional. Zyrtec can actually worsen symptoms, such as wheezing or trouble breathing.