A comparable pattern of systemic CD4 T cell activation was observed in patients with CIS and MS, although patients with MS had a somewhat higher percentage of CD4 T cells in blood expressing CD26, and more CD4 T cells in CSF expressing CD71, than did CIS patients.
Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein.n genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype. The genetic code stored in DNA is interpreted by gene expression, and the properties of the expression give rise to the organism's phenotype.
A genetic modifier, when expressed, is able to alter the expression of another gene. Modifier genes can affect transcription and alter the immediate gene transcript expression, or they can affect phenotypes at other levels of organization by altering phenotypes at the cellular or organismal level (Nadeau, 2001). genetic modifier, when expressed, is able to alter the expression of another gene. Modifier genes can affect transcription and alter the immediate gene transcript expression, or they can affect phenotypes at other levels of organization by altering phenotypes at the cellular or organismal level (Nadeau, 2001).