Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disease and liver cancer. PAs are tumorigenic. Disease associated with consumption of PAs is known as pyrrolizidine alkaloidosis.
The venom is what causes the symptoms. The main symptoms are pain, itching, swelling and redness at the sting site. Severe pain or burning at the site lasts 1 to 2 hours. Itching often follows the pain. Swelling. The bee sting may swell for 48 hours after the sting. The swelling can be small or large.
Bee sting allergies: Symptoms, diagnosis and treatment. A bee sting is painful and irritating for several hours, but not too serious for most people. However, for around 1 in 150 children and 3 in 100 adults, a sting from a bee can trigger a serious allergic reaction, including anaphylactic shock.hen to call 999 for a bee sting. Serious allergic reactions to bee stings are rare, but when they do happen, they are a medical emergency and an ambulance should be called by dialling 999. It is not clear why bee sting allergies develop.