Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disease and liver cancer. PAs are tumorigenic. Disease associated with consumption of PAs is known as pyrrolizidine alkaloidosis.
The venom is what causes the symptoms. The main symptoms are pain, itching, swelling and redness at the sting site. Severe pain or burning at the site lasts 1 to 2 hours. Itching often follows the pain. Swelling. The bee sting may swell for 48 hours after the sting. The swelling can be small or large.
1 Mix baking soda with water; apply paste and let dry. This pulls out venom if applied immediately and works quickly to relieve pain and reduce swelling. 2  If it is a wasp or bee sting, you can mix mud and water together and apply it to the sting.  Do not itch it even if it does get itchy.