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Winnsboro, South Carolina. Winnsboro is a town in Fairfield County, South Carolina, United States. The population was 3,550 at the 2010 census.[4] It is the county seat of Fairfield County.[5] Winnsboro is part of the Columbia, South Carolina Metropolitan Statistical Area.
Sponsored Topics. Winnsboro is a city in Franklin and Wood Counties in the U.S. state of Texas, located 40 miles north of Tyler. The population was 3,584 at the 2000 census. Settlement of Winnsboro began in the 1850s with a post office established in 1855.