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Children (7-10 years): 1  For children aged 7 through 10 years who are not fully immunized with the childhood DTaP vaccine series, Tdap vaccine should be substituted for a single dose of Td vaccine in the catch-up series; if additional doses are needed, use Td vaccine.
Tdap Questions and Answers Q: Is there a difference between DTaP and Tdap? A: Yes, the amounts of diphtheria and pertussis in these vaccines are different. Upper-case letters in these abbreviations denote full-strength doses of diphtheria (D) and tetanus (T) toxoids and pertussis (P) vaccines. Lower-case d and p denote reduced doses of diphtheria and pertussis.DTaP is given to children younger than 7 years of age. Tdap is given to older children and adults.