Toradol (ketorolac): Was given an im injection in the buttocks for migraines and it was completely ineffective. The pain that the injection caused was infuriating considering there was absolutely no relief of the headache..
Examples of full agonists are oxycodone, methadone, codeine, heroin and morphine. PARTIAL AGONISTS. Partial agonists are drugs that bind primarily to mu opioid receptors and cause them to produce endorphins but to a much lesser extent than full agonists. BuprenorphineÂ®, SuboxoneÂ® and SubutexÂ® are partial agonists.
Here is the integrated view : As with agonists, the degree of inverse agonism is based upon the affinity of the ligand for the receptor molecule and the effect may be full inverse agonism or partial inverse agonism. Comparing Inverse Agonists with Partial Agonists and Antagonists