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The major glands of the endocrine system are the pineal gland, pituitary gland, thyroid and parathyroid glands, adrenal glands, pancreas, thymus, ovaries, and testes. There are also other organs in the body that have secondary endocrine functions.These organs include the heart, liver, and kidneys. Hormones can be regulated by other hormones, by glands and organs, and by a negative feedback mechanism. In negative feedback, the initial stimulus is reduced by the response it provokes.he major glands of the endocrine system are the pineal gland, pituitary gland, thyroid and parathyroid glands, adrenal glands, pancreas, thymus, ovaries, and testes. There are also other organs in the body that have secondary endocrine functions.
As a component of the endocrine system, both male and female gonads produce sex hormones. Male and female sex hormones are steroid hormones and as such, can pass through the cell membrane of their target cells to influence gene expression within cells.onads are the male and female primary reproductive organs. The male gonads are the testes and the female gonads are the ovaries. These reproductive system organs are necessary for sexual reproduction as they are responsible for the production of male and female gametes.