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For acute dental and gum infections, examples of suitable antibiotics include (adult doses) for 5 days: amoxicillin 500mg 8-hourly orally, or, metronidazole 400mg 8-hourly orally, or, if penicillin allergic: clarithromycin 500mg 12-hourly orally
Penicillin (Pfizerpen, Pen-Vee K) Traditionally been considered the DOC for the treatment of a dental abscess. Antibiotic therapy alone, without surgical drainage, may not be effective because of poor antibiotic penetration into the abscess cavity, ineffectiveness at low pH levels, and the inoculum effect.