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Making the world better, one answer at a time. The amount of time it take for prescription drugs to get out of your system will depend on the type of medicine it is. Antibiotics take about 8 days to leave the body.he amount of time it take for prescription drugs to get out of your system will depend on the type of medicine it is.
After two hours, youâd have a quarter of the drug left, and after three hours, an eighth. For most medical purposes, a drug is considered to have cleared your system after five half-lives, when only about three percent of the drug is left. Each drug has its own half-life, ranging anywhere from seconds to days. Blood testsâ effective ranges will vary based on the half-life of the drug but are generally sensitive for about one to three days. [ 2 1] Marijuana edibles will linger longer, for up to seven days. 3  Saliva tests range depending on the drug, but most can detect drugs used in the last 12 hours to three days.