Toradol (ketorolac): Was given an im injection in the buttocks for migraines and it was completely ineffective. The pain that the injection caused was infuriating considering there was absolutely no relief of the headache..
Examples of full agonists are oxycodone, methadone, codeine, heroin and morphine. PARTIAL AGONISTS. Partial agonists are drugs that bind primarily to mu opioid receptors and cause them to produce endorphins but to a much lesser extent than full agonists. BuprenorphineÂ®, SuboxoneÂ® and SubutexÂ® are partial agonists.
where K is the dissociation constant for the drug and [D] is its concentration. Partial agonist. An agonist which, no matter how high a concentration is applied, is unable to produce maximal activation of the receptors. In a preparation with a low receptor reserve, it is therefore unable to produce a maximal response.