steve.kubeny@state.mn.us: Jody Derks: Fisheries specialist: 218-739-7576: jody.derks@state.mn.us: Mike Nelson: Fisheries techniian: 218-739-7576: mike.nelson@state.mn.us: Ron Erickson: Fisheries technicia: 218-739-7576: ron.erickson@state.mn.us: Kate Baldwin: Office administrative specialist: 218-739-7576: kate.baldwin@state.mn.us
Experts describe gluconeogenesis as the process by which the liver contributes to the maintenance of normal blood glucose levels (and thus energy metabolism) through synthesis of glucose. This process occurs in the fasting state, such as at night, and requires the presence of amino acids, lactate, and glycerol.
1 The final reaction of gluconeogenesis, the formation of glucose, occurs in the lumen of the endoplasmic reticulum, where glucose-6-phosphate is hydrolyzed by glucose-6-phosphatase to produce glucose and release an inorganic phosphate.he liver uses primarily lactate, alanine and glycerol while the kidney uses lactate, glutamine and glycerol. Propionate is the principal substrate for gluconeogenesis in the ruminant liver, and the ruminant liver may make increased use of gluconeogenic amino acids, e.g. alanine, when glucose demand is increased.