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Cholecystokinin is secreted by I-cells in the small intestine and induces contraction of the gall bladder, relaxes the sphincter of Oddi, reduces of gastric acid secretion, increases bile acid production in the liver, delays gastric emptying, and induces digestive enzyme production in the pancreas.
The human liver produces approximately 400ml to 800ml of bile each day. Hepatocytes of the liver secrete bile, which is then released into the canaliculi before entering the bile ducts.The bile ducts add to this secretion a liquid rich with bicarbonates. Next, a hormone called cholecystokinin (CCK), causes gall bladder contraction, which discharges bile into the duodenum.he human liver produces approximately 400ml to 800ml of bile each day. Hepatocytes of the liver secrete bile, which is then released into the canaliculi before entering the bile ducts.