Definition of neuralgia. : acute paroxysmal pain radiating along the course of one or more nerves usually without demonstrable changes in the nerve structure.
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It has been most extensively studied as treatment for generalized anxiety disorder (GAD). Three trials that involved >2,100 patients found quetiapine XR monotherapy is effective for GAD in doses of 50 to 300 mg/d. In 2 of the studies, quetiapine XR was as effective as paroxetine and escitalopram for GAD.