PCR is short for polymerase chain reaction and is a method we can use to clone sequences of DNA. We often want to clone these sequences a whole bunch (on the order of a billion copies of a single sequence!), so technology is obviously involved. This is how it works: DNA is collected from somewhere.
E. Nazareth was an isolated city, did not take in many visitors, had the worst cultural habits in Galilee, had a bad name among neighboring towns perhaps due to lack of religious adherence and low morals. -example - there may be a location within your community that has a bad reputation, not an ideal place to live.
In Luke's Gospel, Nazareth is first described as 'a town of Galilee' and home of Mary (Luke 1:26). Following the birth and early epiphanial events of chapter 2 of Luke's Gospel, Mary, Joseph and Jesus returned to Galilee, to their own city, Nazareth.