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Pagetâs disease causes bones to grow too large and weak. You can have Pagetâs disease in any bones in your body, but most people have it in their spine, pelvis, skull, or leg bones. The disease may affect only one bone or several bones, but it does not affect the entire skeleton.f you have Pagetâs disease in your leg bones, you may also have bowed legs. Your spine might curve if the disease is in the bones of the spine. People with Pagetâs disease in the bones of the skull sometimes have: 1  Headaches. 2  Hearing loss. 3  Large head size.
Osteomalacia is a disease that causes an adultâs bones to soften, resulting in muscle weakness and bone pain. The most common cause of osteomalacia is a lack of vitamin D. In children osteomalacia is known as rickets.People at risk for developing soft bones typically possess one or more risk factors associated with low vitamin D levels.steomalacia is caused by a dysfunction in the bone-building process. Because vitamin D is needed to build strong bones, any disorder that affects vitamin D levels in your body will affect your bones.