Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disease and liver cancer. PAs are tumorigenic. Disease associated with consumption of PAs is known as pyrrolizidine alkaloidosis.
The venom is what causes the symptoms. The main symptoms are pain, itching, swelling and redness at the sting site. Severe pain or burning at the site lasts 1 to 2 hours. Itching often follows the pain. Swelling. The bee sting may swell for 48 hours after the sting. The swelling can be small or large.
Brown Recluse Spider Bites. The bite of a brown recluse spider is usually painless, but may feel like a mild bee sting. Symptoms of a brown recluse spider bite include severe pain at the site of the bite that develops about four hours after the bite; followed by severe itching, nausea, vomiting, fever, and muscle pain. See a doctor immediately if you think you have been bitten by a brown recluse spider bite.