The lender must document that the existing loan being refinanced is owned (or securitized) by Fannie Mae. Documentation may come from the lenderâs servicing system, the current servicer (if the lender is not the. servicer), from Fannie Maeâs Loan Lookup Tool (https://knowyouroptions.com/loanlookup ) or any other.
Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart (called coronary arteries). Plaque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time.This process is called atherosclerosis.Coronary artery disease (CAD) is the most common type of heart disease in the United States.For some people, the first sign of CAD is a heart attack.laque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time. This process is called atherosclerosis. Coronary artery disease (CAD) is the most common type of heart disease in the United States. For some people, the first sign of CAD is a heart attack.
Some hardening of the arteries is normal as you age. Exactly how atherosclerosis begins or what causes it isn't known, but some theories have been proposed. Many scientists believe plaque begins when an arteryâs inner lining (called the endothelium) becomes damaged. Three possible causes of damage are: Elevated levels of cholesterol and triglycerides in the blood; High blood pressure; Cigarette smoking; Smoking has a big role in the growth of atherosclerosis in the coronary arteries, aorta and arteries in the legs. It makes fatty deposits more likely to form and to grow bigger and faster. This content was last reviewed April 2017.