Federal Home Loan Mortgage Corporation: FRM: fixed-rate mortgage: GAAP: generally accepted accounting principles: GSE: government-sponsored enterprise: HCLTV: home equity combined loan-to-value: HELOC: home equity line of credit: HFA: Housing Finance Agency: HOA: homeownersâ association: HOEPA: Home Ownership and Equity Protection Act of 1994
Hydrogen bonds, as well as the other types of noncovalent interactions, are very important in terms of the binding of a ligand to a protein. In section 1.3, we saw a 'space-filling' picture of an enzyme with its substrate bound in its active site.
But, only molecules which have polar covalent bonds can do this, non polar covalent bonds cannot form a hydrogen bond. A hydrogen bond is one kind of weak bonds. Other forms of weak bonds are ionic bonds and van der Waals interaction. Weak bonds are attractions which forms easily and quickly and do not a need large amount of energy to break because they are easily broken under natural biological conditions.