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Pagetâs disease causes bones to grow too large and weak. You can have Pagetâs disease in any bones in your body, but most people have it in their spine, pelvis, skull, or leg bones. The disease may affect only one bone or several bones, but it does not affect the entire skeleton.f you have Pagetâs disease in your leg bones, you may also have bowed legs. Your spine might curve if the disease is in the bones of the spine. People with Pagetâs disease in the bones of the skull sometimes have: 1  Headaches. 2  Hearing loss. 3  Large head size.
While some people may be born with a bone disease as a result of faulty genes or inborn errors of metabolism, some people may develop degenerative bone diseases, later in life. Given below is some information on some of the common and rare bone disorders that may affect children or adults.Osteoporosis.Osteoporosis is a disease which is characterized by a gradual loss of bone mineral density. Bones are calcified tissues that have the ability to repair themselves. However, as some people age, the mineralization of bones doesn't take place in the right manner.ancer can start in another part of the body and spread to bones. Bone pain, swelling, development of a mass on the affected bone, fatigue and weakened bones are some of the symptoms of bone cancer. On a concluding note, bone diseases could be congenital or degenerative.