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Ganglion Cyst Quick Overview. A ganglion cyst is a tumor or swelling (benign, not cancerous) usually on top of a joint or the covering of a tendon (tissue that connects muscle to bone). It looks like a sac of liquid (cyst) located just under the skin. Inside the cyst is a thick, sticky, clear, colorless, jellylike material.
More in Orthopedics. A wrist ganglion cyst is a swelling that usually occurs over the back of the hand or wrist. These are benign, fluid-filled capsules. Ganglion cysts are not cancerous, will not spread, and while they may grow in size, they will not spread to other parts of your body.