World Changes Due to the Telephone. Within 50 years of its invention, the telephone had become an indispensable tool in the United States. In the late 19th century, people raved about the telephone's positive aspects and ranted about what they anticipated would be negatives.
When you hold the ice cube for a very long time, the enzymes deactivate. Blood circulation stops. The brain initiates impulses for blood circulation. The local nerves therefore get irritated and produce a sensation of heat.
Given your family history and the fact that this happens every time you touch something cold, I would suggest two things: 1  Protect yourself from the cold. For example, avoid holding cold cans, don't wash garments in cold water, and be sure to wear gloves outdoors.  Get tested.