5-FU injection and topical even in small doses cause both acute central nervous system (CNS) damage and progressively worsening delayed degeneration of the CNS in mice. This latter effect is caused by 5-FU-induced damage to the oligodendrocytes that produce the insulating myelin sheaths.
Home > Sexually transmitted infections > Syphilis > After treatment for syphilis. It is strongly advised that you do not have any sexual intercourse; including vaginal; anal or oral sex until you and your partner(s) have both finished the treatment and any follow-up treatment.
Primary stage. During the primary stage of syphilis, a sore (chancre) that is usually painless develops at the site where the bacteria entered the body. This commonly occurs within 3 weeks of exposure but can range from 10 to 90 days. A person is highly contagious during the primary stage.