Cramping or pain in a leg caused by poor blood circulation. This condition is frequently caused by hardening of the arteries (atherosclerosis). Intermittent claudication occurs only at certain times, usually after exercise, and is relieved by rest.
RESULTS: 22% (29/129) of respondents admitted to abusing gabapentinoids, and of these, 38% (11/29) abused gabapentinoids in order to potentiate the 'high' they obtained from methadone. CONCLUSIONS: Gabapentinoid abuse along with methadone has not previously been described.
2) Gabapentin has been associated with an increased risk of suicidal acts or violent deaths. 3) Abrupt withdrawal will cause suffering. 4) Gabapentin's most common side effects in adult patients include dizziness, fatigue, weight gain, drowsiness, and edema.5) In certain cases, susceptibility to mild-to-moderate mood swings, hostility, concentration problems, liver damage and hyperactivity have been observed.) It produces psychoactive effects that cause it to have potential for recreational use. Even in low doses, gabapentin causes sensations of reduced acute pain and reduced anxiety.