If you leave the fat cap on a brisket, you should consider injecting brine. Spices do not penetrate muscle more than a fraction of an inch, but they do flavor the surface and help form the crust. If you coated the meat with a wonderful spice rub, it will remain on top of the fat and not get onto the meat.
Drinking too much alcohol on a regular basis almost always causes liver damage, although not always cirrhosis. Drinking 32 to 48 oz. of beer, 4 to 8 oz. of liquor, or 16 to 32 oz. of wine every day for 10 to 15 years or longer greatly increases your chances of developing cirrhosis.
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