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Neulasta side effects. Get emergency medical help if you have signs of an allergic reaction to Neulasta: hives, skin rash, flushing (warmth, redness, or tingly feeling); wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat. A rare but serious side effect of Neulasta is called capillary leak syndrome.
Neulasta (pegfilgrastim) is  a man-made form of a protein that stimulates the growth of white blood cells in your body. White blood cells help your body fight against infection. Neulasta is used to prevent neutropenia, a lack of certain white blood cells caused by receiving chemotherapy.