Hello Lisagarmaise, Serotonin is to blame! Excessive release of 5HT(serotonin) from intestinal mucosa cells can cause diarrhea and nausea. Metformin stimulates these intestinal cells to produce increased levels of 5HT, as soon as 10-15 minutes after taking metformin. The good news is that most symptoms dissapear after taking metformin for 2-3 weeks.
Progesterone, hormone secreted by the female reproductive system that functions mainly to regulate the condition of the inner lining (endometrium) of the uterus. Progesterone is produced by the ovaries, placenta, and adrenal glands.
The hormones secreted by the thyroid gland are the triiodothyronine (T3), thyroxine (T4) and the thyrocalcitonin which is responsible for the calcium reabsorption or breakdown. T3 and T4 are the two primary hormones responsible for metabolism. The anterior pituitary gland signals the thyroid gland to secrete hormones.s I have said earlier, the thyroid gland is responsible for the regulation of the metabolism of the body. This means that the thyroid secretes hormones that are responsible for burning the calories, fats and other nutrients used by our body for energy.