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Neutropenia is classified as mild, moderate, or severe, based on the ANC. Mild neutropenia is present when the ANC is 1000-1500 cells/ÂµL, moderate neutropenia is present with an ANC of 500-1000/ÂµL, and severe neutropenia refers to an ANC lower than 500 cells/ÂµL. The risk of bacterial infection is related to both the severity and duration of the neutropenia.
Neutropenic enterocolitis is a life-threatening, necrotizing enterocolitis occurring primarily in neutropenic patients [1]. Neutropenic enterocolitis occurs most commonly in individuals with hematologic malignancies who are neutropenic and have breakdown of gut mucosal integrity as a result of cytotoxic chemotherapy.