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Neulasta side effects. Get emergency medical help if you have signs of an allergic reaction to Neulasta: hives, skin rash, flushing (warmth, redness, or tingly feeling); wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat. A rare but serious side effect of Neulasta is called capillary leak syndrome.
To make sure you can safely use Neulasta, tell your doctor if you have any of these other conditions: 1  sickle cell disorder; 2  kidney disease; 3  chronic myeloid leukemia; 4  myelodysplasia (also called preleukemia); or. 5  a latex allergy.