Background. The etiology of vitamin B12 deficiency is diverse and includes lack of intrinsic factor (IF), altered pH in the small intestine, and lack of absorption of B12 complexes in the terminal ileum. Vitamin B12 deficiency from any cause, as well as folic acid deficiency, can result in megaloblastic anemia.he etiology of vitamin B12 deficiency is diverse and includes lack of intrinsic factor (IF), altered pH in the small intestine, and lack of absorption of B12 complexes in the terminal ileum.
The Last Supper (Italian: Il Cenacolo [il tÊeËnaËkolo] or L'Ultima Cena [Ëlultima ËtÊeËna]) is a late 15th-century mural painting by Leonardo da Vinci in the refectory of the Convent of Santa Maria delle Grazie, Milan. It is one of the world's most famous paintings.
In 1483, Leonardo, with his pupil Ambrogio de Predis, was commissioned to execute the famous Madonna of the Rocks. Two versions of the painting existâone in the Louvre (1483âc.1486), another in the National Gallery, London (1483â1508). Leonardo's fresco of the Last Supper (Milan) was begun c.1495 and completed by 1498.