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The Parkes Weber syndrome is a congenital vascular malformation, characterized by varicose veins, arterio-venous fistulas and overgrown limbs. No broadly accepted animal model of Parkes Weber syndrome has been described. We created side-to-side arterio-venous fistula between common ...
(See 'Differential diagnosis' below.) âChronic kidney disease (CKD) â Some patients with multiple myeloma may experience a gradual or progressive increase in serum creatinine over a period of six months or more. These patients are less likely to have a diagnosis of light chain cast nephropathy. However, patients who have experienced one or more prior episodes of light chain cast nephropathy without complete renal recovery can develop CKD. CKD as a presenting clinical feature is more commonly seen in patients with immunoglobulin light chain (AL) amyloidosis or monoclonal immunoglobulin deposition disease (MIDD).