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Hemosiderin collects throughout the body in hemochromatosis. Hemosiderin deposition in the liver is a common feature of hemochromatosis and is the cause of liver failure in the disease. Deposition in the pancreas leads to diabetes and in the skin leads to hyperpigmentation.
There may be several reasons for ascites: 1  If cancer cells have spread to the lining of the tummy, they can irritate it and cause fluid to build up. 2  If the liver is affected by cancer cells, this may block the circulation of blood through the liver. 3  If the liver is damaged, it may produce less blood protein.