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Finally, with further decreases in the levels of CD4 cells, the person develops AIDS. According to the CDC, for an HIV-infected person, some signs that AIDS has developed (known as AIDS-defining conditions) are: The CD4 cell count has decreased to fewer than 200 cells per cubic milliliter of blood.
How AIDS develops. 1  The immune system is gradually disrupted. 2  Virus levels in the blood and the lymph nodes increase because the immune system cannot keep up with the amount of virus constantly produced. 3  HIV constantly changes itself, avoiding attack by the antibodies and immune cells that normally control infections.