The carrier frequency and incidence of alpha thalassemia vary by the type and population. Carrier frequency of this condition is reported to be the highest in individuals of Southeast Asian, African, West Indian, and Mediterranean descent.
Clitheroe Castle Museum is adjacent to the castle. The castle was listed as a Scheduled Monument on 10 April 1915 (and later, under the Ancient Monuments and Archaeological Areas Act 1979 law).It was Grade I listed on 19 May 1950.t has been suggested that Clitheroe Castle may have been first built before 1086 as there is reference to the  castellatu Rogerii pictaviensis  in the Domesday Book entry for nearby Barnoldswick. However, it is likely the passage refers to another castle.
The Pagoda is a notable example of a beautiful property situated in Blackheath, built in 1760 by Sir William Chambers in the style of a traditional Chinese pagoda. It was later leased to the Prince Regent, who would become King George IV, and used as a summer home by his wife Caroline, Princess of Wales.lackheath also gave its name to the first hockey club, established during the mid 19th century. However, Blackheath is perhaps most famous for founding the Blackheath Rugby Club in 1858, which is the oldest documented rugby club in England and located on Charlton Road.