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Normal platelet count in a micro litre of human blood is 150000 to 450000. Slight decrease in the platelet count does not contribute to the disease but when it is below 50,000 per micro litre, thrombocytopenia occurs. Low platelet count in dengue fever can be very dangerous.The reasons for low platelet count in dengue fever are as follows. Dengue virus, the main cause of dengue fever induces bone marrow suppression.Since bone marrow is the manufacturing centre of blood cells its suppression causes deficiency of blood cells leading to low platelet count.Anaemia and spontaneous severe bleeding are the other resultant factors of bone marrow suppression.his is one of the major causes of low platelet count in dengue fever. Even the antibodies that are produced after infection of dengue virus can contribute in destruction of platelets, thus lowering the platelet count.
A platelet count below 150,000 per mcL is called thrombocytopenia, while a platelet count over 450,000 is called thrombocytosis. Platelets seem to have a large backup capacity: blood typically still clots normally as long as the platelet count is above 50,000 per mcL (assuming no other problems are present).Spontaneous bleeding doesnât usually occur unless the platelet count falls to 10,000 or 20,000 per mcL.latelets are constantly being produced in the bone marrow. A low or high platelet count is not often a problem by itself, but can frequently be a sign of another medical condition. For this reason, high or low platelet counts require additional medical attention.