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It is difficult to tell. However, people have been burning up Twitter with tweets on the topic for days. Somebody even a fired up a Facebook page to add to the fun:  Make 4/21 National Drug Test Day .. With the motto Detox can't save ya now, the page has been liked by over 1,200 people.ecause there is no such holiday, officially or unofficially, as National Surprise Drug Test Day. No 4/21 to follow 4/20: National Pot Day, apparent fake holiday precursor.
Drug Tests Often Trigger False Positives. May 28, 2010 (New Orleans) -- If your child insists his positive drug test results are a mistake, there's a chance he could be telling the truth. Drug tests generally produce false-positive results in 5% to 10% of cases and false negatives in 10% to 15% of cases, new research shows.