The carrier frequency and incidence of alpha thalassemia vary by the type and population. Carrier frequency of this condition is reported to be the highest in individuals of Southeast Asian, African, West Indian, and Mediterranean descent.
Clitheroe Castle Museum is adjacent to the castle. The castle was listed as a Scheduled Monument on 10 April 1915 (and later, under the Ancient Monuments and Archaeological Areas Act 1979 law).It was Grade I listed on 19 May 1950.t has been suggested that Clitheroe Castle may have been first built before 1086 as there is reference to the  castellatu Rogerii pictaviensis  in the Domesday Book entry for nearby Barnoldswick. However, it is likely the passage refers to another castle.
Features of castles changed greatly throughout the centuries. A motte and bailey castle, for example, prevalent in France after the viking invasion and England after 1066, consisted of a huge mound of earth with a tower on top.An early stone castle consisted of one stone keep, sometimes huge in size (e.g Rochester) and perhaps a ditch around the outside.edingham is typical of English castles since it was really two (perhaps three) different castles built on the same site. The original, first castle was a simple motte-and-b â¦ ailey built by Sir Aubrey de Vere in about 1100.