In HIT, the immune system forms antibodies against heparin when it is bound to a protein called platelet factor 4 (PF4). These antibodies are usually of the IgG class and their development usually takes about five days.
The first elevator shaft preceded the first elevator by four years. Construction for Peter Cooper's Cooper Union Foundation building in New York began in 1853. An elevator shaft was included in the design, because Cooper was confident that a safe passenger elevator would soon be invented.
In Los Angeles County, permit fees will add to the cost of a home elevator in the cities of Los Angeles, La Canada-Flintridge and Manhattan Beach. A standard-size elevator is 12 to 15 square feet, and a mid-size is 15 to 18 square feet. Some luxury homes will have even larger commercial elevators or more than one lift. With so many variables, costs can range from $25,000 to $125,000 or more to add an elevator to an existing house. Hoping to tap into the growing demand for design-oriented elevators, Elevator Boutique of Australia opened a showroom this year in the Pacific Design Center in West Hollywood.