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Androgen: A male sex hormone that promotes the development and maintenance of the male sex characteristics. The major androgen is testosterone.
1 Androgen replacement therapy (andropausal and ergogenic use) is a hormone treatment often prescribed to counter the effects of male hypogonadism. 2  It is also prescribed to lessen the effects or delay the onset of normal male aging. It is often referred to as treatment rather than therapy. 2  Hormone replacement therapy for transgender people introduces hormones associated with the gender that the patient identifies with (notably testosterone for trans men and estrogen for trans women).