fourthyearmed Senior Member 5+ Year Member. Yes, 3rd year is long, hard, a lot of work, and has tests but I still enjoyed it so much more than the HELL that was 1st and 2nd years. 3rd year involves interaction not just with patients but with other people in the medical field besides your classmates.
The mitotic spindle is the macromolecular machine that segregates chromosomes to two daughter cells during mitosis. The major structural elements of the spindle are microtubule polymers, whose intrinsic polarity and dynamic properties are critical for bipolar spindle organization and function.he mitotic spindle is the macromolecular machine that segregates chromosomes to two daughter cells during mitosis. The major structural elements of the spindle are microtubule polymers, whose intrinsic polarity and dynamic properties are critical for bipolar spindle organization and function.
Spindle fibers are a part of the spindle apparatus, which moves chromosomes during mitosis and meiosis to ensure each daughter cell gets the correct number of chromosomes. The spindle apparatus consists of spindle fibers, motor proteins, chromosomes, and in some cells, structures called asters. In animal cells, spindle fibers are produced from cylindrical microtubules called centrioles. Centrioles form asters and asters generate spindle fibers during the cell cycle. Centrioles are located in a region of the cell known as the centrosome. Spindle Fibers and Chromosome Movement