Hello Lisagarmaise, Serotonin is to blame! Excessive release of 5HT(serotonin) from intestinal mucosa cells can cause diarrhea and nausea. Metformin stimulates these intestinal cells to produce increased levels of 5HT, as soon as 10-15 minutes after taking metformin. The good news is that most symptoms dissapear after taking metformin for 2-3 weeks.
Progesterone, hormone secreted by the female reproductive system that functions mainly to regulate the condition of the inner lining (endometrium) of the uterus. Progesterone is produced by the ovaries, placenta, and adrenal glands.
Report Abuse. Both secrete hormones. Exocrine glands secrete hormones via a duct often externally e.g. ducts in skin, eyes etc., endocrine hormones are secreted into the bloodstream so that they can quickly be dispersed to their effector cells. DragonReborn Â· 3 years ago. Thumbs up.