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Hemosiderin collects throughout the body in hemochromatosis. Hemosiderin deposition in the liver is a common feature of hemochromatosis and is the cause of liver failure in the disease. Deposition in the pancreas leads to diabetes and in the skin leads to hyperpigmentation.
Increases in eosinophils are also seen in response to collagen vascular disorders. Collagen vascular. disorders are a group of acquired disorders that have in common widespread inflammation in blood. vessels and connective tissue. Eosinophilic gastroenteritis can also cause the eosinophil level to be. too high. Eosinophilic gastroenteritis is a condition in which eosinophils of the blood pass into the. mucous membranes of the small intestine.