5-FU injection and topical even in small doses cause both acute central nervous system (CNS) damage and progressively worsening delayed degeneration of the CNS in mice. This latter effect is caused by 5-FU-induced damage to the oligodendrocytes that produce the insulating myelin sheaths.
Home > Sexually transmitted infections > Syphilis > After treatment for syphilis. It is strongly advised that you do not have any sexual intercourse; including vaginal; anal or oral sex until you and your partner(s) have both finished the treatment and any follow-up treatment.
Primary syphilis usually breaks out about 3 weeks after exposure but can range from 9 to 30 days after exposure. The chancre will last from 3 to 6 weeks and then will disappear with or without treatment. The infection will persist even when the ulcer leaves, unless antibiotics are used. The rash of secondary syphilis occurs 2 to 10 weeks after the chancre appears, often after the chancre is completely gone.