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Neutropenia is classified as mild, moderate, or severe, based on the ANC. Mild neutropenia is present when the ANC is 1000-1500 cells/ÂµL, moderate neutropenia is present with an ANC of 500-1000/ÂµL, and severe neutropenia refers to an ANC lower than 500 cells/ÂµL. The risk of bacterial infection is related to both the severity and duration of the neutropenia.
ANC: The absolute neutrophil count, the number of white blood cells (WBCs) that are neutrophils. The ANC is not measured directly. It is derived by multiplying the WBC count times the percent of neutrophils in the differential WBC count.The percent of neutrophils consists of the segmented (fully mature) neutrophils) + the bands (almost mature neutrophils).The normal range for the ANC = 1.5 to 8.0 (1,500 to 8,000/mm3).NC: The absolute neutrophil count, the number of white blood cells (WBCs) that are neutrophils. The ANC is not measured directly. It is derived by multiplying the WBC count times the percent of neutrophils in the differential WBC count.