In HIT, the immune system forms antibodies against heparin when it is bound to a protein called platelet factor 4 (PF4). These antibodies are usually of the IgG class and their development usually takes about five days.
The first elevator shaft preceded the first elevator by four years. Construction for Peter Cooper's Cooper Union Foundation building in New York began in 1853. An elevator shaft was included in the design, because Cooper was confident that a safe passenger elevator would soon be invented.
Official Web site for Otis Elevator The company, founded by Elisha Graves Otis, web site.Otis is part of United Technologies Corporation, a Fortune 500 company and world leader in the building systems. (URL: www.otis.com) Elevator History The earliest lifts used man, animal and water power to raise the load.