Hello Lisagarmaise, Serotonin is to blame! Excessive release of 5HT(serotonin) from intestinal mucosa cells can cause diarrhea and nausea. Metformin stimulates these intestinal cells to produce increased levels of 5HT, as soon as 10-15 minutes after taking metformin. The good news is that most symptoms dissapear after taking metformin for 2-3 weeks.
Progesterone, hormone secreted by the female reproductive system that functions mainly to regulate the condition of the inner lining (endometrium) of the uterus. Progesterone is produced by the ovaries, placenta, and adrenal glands.
37.6]lu contains endocrine cells that secrete prolactin, growth hormone, and several trophic hormones that stimulate other endocrine glands (see Table 37.2). -Hypothalamus secretes releasing and release-inhibiting hormones that control the anterior lobe of the pituitary. Hypothalamus links nervous and endocrine systems. - Hypothalamic neurons secrete hormones that regulate the release of hormones from the anterior lobe of the pituitary gland. Pituitary hormones, in turn, control activity of other endocrine glands.