Mutations in the TCOF1, POLR1C, or POLR1D gene can cause Treacher Collins syndrome. TCOF1 gene mutations are the most common cause of the disorder, accounting for 81 to 93 percent of all cases. POLR1C and POLR1D gene mutations cause an additional 2 percent of cases.
B vitamins stimulate immune T cells that recognize and destroy pathogens. The research team examined how byproducts of bacterial vitamin synthesis, including some derived from Folic acid or vitamin B9 and Riboflavin or vitamin B2, could be captured by the immune receptor cells to fine-tune the activity of T cells.
Vitamin B5 (pantothenic acid): Deficiencies of this vitamin are rare, but may lead to symptoms of fatigue and depression. Vitamin B6 (pyridoxine): This vitamin helps your body process amino acids, which are the building blocks of all proteins and some hormones. It is needed to make serotonin, melatonin and dopamine. Vitamin B6 deficiencies, although very rare, cause impaired immunity, skin lesions, and mental confusion.