Of or pertaining to James the First, of England, or of his reign or times; especially, pertaining to a style of architecture and decoration popular in the time of James I.; as, Jacobean writers. Etymology: From L. Jacobus James.
ALS is a progressive, degenerative disease of the nervous system. It is one of a group of diseases, called motor neuron diseases (MND), in which specialized nerve cells that control movement of the voluntary muscles gradually cease functioning and die. Fasciculation is a sign of muscle irritability, as the normal action of the lower motor neuron on the muscle is impaired. 2  The sole involvement of lower motor neurons can be seen in a form of ALS called progressive muscular atrophy.
What is progressive supranuclear palsy? Progressive supranuclear palsy (PSP) is an uncommon brain disorder that affects movement, control of walking (gait) and balance, speech, swallowing, vision, mood and behavior, and thinking. The disease results from damage to nerve cells in the brain. The disorderâs long name indicates that the disease worsens (progressive) and causes weakness (palsy) by damaging certain parts of the brain above nerve cell clusters called nuclei (supranuclear). These nuclei particularly control eye movements.