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In biochemistry, a ligase is an enzyme that can catalyze the joining of two large molecules by forming a new chemical bond, usually with accompanying hydrolysis of a small pendant chemical group on one of the larger molecules or the enzyme catalyzing the linking together of two compounds, e.g., enzymes that catalyze joining of C-O, C-S, C-N, etc.
Types of enzymes. Each enzyme can usually only be the catalyst for a single reaction. For example, the enzyme maltase is the catalyst for changing maltose into glucose. Notice that the name of the enzyme is usually very similar to the substance it works on: maltase works on maltose.Enzymes have the ending-ase.or example, the enzyme maltase is the catalyst for changing maltose into glucose. Notice that the name of the enzyme is usually very similar to the substance it works on: maltase works on maltose. Enzymes have the ending-ase.