Cramping or pain in a leg caused by poor blood circulation. This condition is frequently caused by hardening of the arteries (atherosclerosis). Intermittent claudication occurs only at certain times, usually after exercise, and is relieved by rest.
RESULTS: 22% (29/129) of respondents admitted to abusing gabapentinoids, and of these, 38% (11/29) abused gabapentinoids in order to potentiate the 'high' they obtained from methadone. CONCLUSIONS: Gabapentinoid abuse along with methadone has not previously been described.
(6) There are numerous reports of experimentation with gabapentin alone and in combination with other substances. Effects reported vary with the user, dosage, past experience, psychiatric history, and expectations; indeed some reporters admit to a possible placebo effect.he second case described a 63-year-old man with a prior history of abusing alcohol who was taking gabapentin 4900 mg/day instead of the prescribed 1800 mg/day. Following presentation to hospital and discontinuation of gabapentin he developed severe withdrawal symptoms.