Of or pertaining to James the First, of England, or of his reign or times; especially, pertaining to a style of architecture and decoration popular in the time of James I.; as, Jacobean writers. Etymology: From L. Jacobus James.
ALS is a progressive, degenerative disease of the nervous system. It is one of a group of diseases, called motor neuron diseases (MND), in which specialized nerve cells that control movement of the voluntary muscles gradually cease functioning and die. Fasciculation is a sign of muscle irritability, as the normal action of the lower motor neuron on the muscle is impaired. 2  The sole involvement of lower motor neurons can be seen in a form of ALS called progressive muscular atrophy.
So, what is muscle atrophy and what can be done to reverse it? Muscle atrophy is the loss or decrease of muscle mass. The synonyms for it are muscle wasting, muscle loss, muscle catabolism, muscle withering. The cause of muscle atrophy are a lack of use of the muscle or a disruption of the nerve signals to the muscle. It is seen in many conditions, especially with cachexia in cancer and HIV/AIDS. The cure for muscle atrophy is using the muscle, most easily through exercise and being active in normal daily activities.