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Neulasta side effects. Get emergency medical help if you have signs of an allergic reaction to Neulasta: hives, skin rash, flushing (warmth, redness, or tingly feeling); wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat. A rare but serious side effect of Neulasta is called capillary leak syndrome.
Neulasta is prescribed to cancer patients undergoing chemotherapy who may have low white blood cell counts and are at risk for infection. According to Amgen, the manufacturer of Neulasta, the medication works by boosting the production of white cells by the bone marrow.