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Hemosiderin collects throughout the body in hemochromatosis. Hemosiderin deposition in the liver is a common feature of hemochromatosis and is the cause of liver failure in the disease. Deposition in the pancreas leads to diabetes and in the skin leads to hyperpigmentation.
Other possible causes of hydronephrosis include: 1  Blood clots in the kidney or ureter. 2  Narrowing or stricture of the urinary tract due to injury, infection, birth defects or surgery.3  Nerve or muscle problems that affect the kidneys or ureters.4  Urinary retention due to an inability to empty the bladder.ther possible causes of hydronephrosis include: 1  Blood clots in the kidney or ureter. 2  Narrowing or stricture of the urinary tract due to injury, infection, birth defects or surgery.