In November 1887, Patrick Joseph P.J. Kennedy married Mary Augusta Hickey, daughter of James Hickey of Cork, Ireland, and Margaret M. Field, also of Ireland. Their son, Joseph Patrick Kennedy, was born on September 6, 1888 in East Boston.
Tau is a protein found in neurons, where it works to stabilize the shape and function of the cell. As part of normal function, proteins in the body fold, unfold and refold into different shapes in order to perform specific functions, and when they are no longer needed, they are broken down and recycled by the cell.
Natural unsaturated fatty acids are in configuration that is called cis, but partial hydrogenation can flip the chemical bonds into a different configuration that is called trans. The difference between cis and trans is that the two H atoms are on the same side of the double bond (cis), compared to being on opposite sides (trans). This may not seem like much of a difference, but it affects the shapes of the molecules. In a cis configuration, the double bond creates a kink in the fatty acid. In the trans configuration, there is no kink. Therefore, a trans-fatty acid is structurally similar to a saturated fatty acid (which has no kinks, either). The kinks in the molecules determine whether the material is solid or liquid at room temperature.