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/imÂ·muÂ·noÂ·comÂ·proÂ·mised/ (-komÂ´pro-mÄ«zd) having the immune response attenuated by administration of immunosuppressive drugs, by irradiation, by malnutrition, or by certain disease processes (e.g., cancer).
Immune reconstitution inflammatory syndrome is a condition seen in some cases of AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.