In HIT, the immune system forms antibodies against heparin when it is bound to a protein called platelet factor 4 (PF4). These antibodies are usually of the IgG class and their development usually takes about five days.
The first elevator shaft preceded the first elevator by four years. Construction for Peter Cooper's Cooper Union Foundation building in New York began in 1853. An elevator shaft was included in the design, because Cooper was confident that a safe passenger elevator would soon be invented.
The building used to hold the record for the fastest ascending elevator (16.83 m/s) and for the largest countdown clock which is displayed on New Yearâs Eve. Taipei 101 is also one of the most stable buildings ever to be constructed. Its foundation is reinforced by 380 pillars driven 80 meters into the ground.