cerebral cortex. The outer layer of gray matter that covers the cerebral hemispheres in the brain of many vertebrate animals and is composed of folds of nerve cells and fibers.erebral cortex. The outer layer of gray matter that covers the cerebral hemispheres in the brain of many vertebrate animals and is composed of folds of nerve cells and fibers.
Dopamine blockers and depletors are used to treat conditions that arise from the over-production or increased activity of dopamine. Dopamine blockers work by binding to and blocking the action of dopamine receptors.his prevents the receptors from using the dopamine that is present in the brain or elsewhere in the body. Conversely, dopamine depletors work by preventing dopamine from being stored or released by neurons. There are numerous types of dopamine blockers and depletors.
Dopamine is a neurotransmitter, a chemical used to carry messages between neurons. Dopamine is produced in several areas of the brain, including the substantia nigra. Dopamine's effects are complex and poorly understood, but dopamine appears to play a role in signaling reward in the brain.arkinson's disease destroys dopamine-producing neurons in the substantia nigra, and causes motor symptoms (dyskinesia, tremor, rigidity) as well as cognitive symptoms. The motor symptoms can be treated by drugs that increase brain dopamine levels.