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Back to Top Causes. Hypothyroidism in the newborn may be caused by: 1  A missing or poorly developed thyroid gland. 2  A pituitary gland that does not stimulate the thyroid gland. 3  Thyroid hormones that are poorly formed or do not work.
TSH causes the thyroid gland to make two hormones: triiodothyronine (T3) and thyroxine (T4). T3 and T4 help control your body's metabolism. Triiodothyronine (T3) and thyroxine (T4) are needed for normal growth of the brain, especially during the first 3 years of life.A baby whose thyroid gland does not make enough thyroid hormone (congenital hypothyroidism) may, in severe cases, be mentally retarded. Find the cause of an underactive thyroid gland (hypothyroidism). 2  TSH levels can help determine whether hypothyroidism is due to a damaged thyroid gland or some other cause (such as a problem with the pituitary gland or the hypothalamus).