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Similar to heroin, oxycodone produces â along with pain management â a euphoric high caused by stimulation of the reward center of the brain. Oxycodone elevates levels of the neurotransmitter dopamine, which is considered the pleasure chemical of the brain. On the street, OxyContin is known as âOxy,â âOC,â âOxyCotton,â âHillbilly Heroin,â and âKickers,â and is often used if heroin or morphine is not available.
Other than a drug test, one can use the following symptoms to detect oxycodone or OxyContin abuse: 1  Drowsiness, sometimes to the point of nodding off. 2  Sedation. 3  Euphoria. Lightheadedness. 4  Itching. Nausea and vomiting. 5  Constipation. Low blood pressure.  Respiratory 1  suppression. 2  Headache. 3  Dry mouth.  Sweating.