The carrier frequency and incidence of alpha thalassemia vary by the type and population. Carrier frequency of this condition is reported to be the highest in individuals of Southeast Asian, African, West Indian, and Mediterranean descent.
Clitheroe Castle Museum is adjacent to the castle. The castle was listed as a Scheduled Monument on 10 April 1915 (and later, under the Ancient Monuments and Archaeological Areas Act 1979 law).It was Grade I listed on 19 May 1950.t has been suggested that Clitheroe Castle may have been first built before 1086 as there is reference to the  castellatu Rogerii pictaviensis  in the Domesday Book entry for nearby Barnoldswick. However, it is likely the passage refers to another castle.
The largest in England, Windsor Castle is one of the principal residences of the queen and covers nearly thirteen acres. The first castle on the site was set up by William the Conqueror in about 1070. Windsor is the only royal castle that has been in continuous occupation since the Middle Ages and is the largest inhabited castle in the world. Almost every century from the 12th. to the 19th. left its mark on this great fortress.