In November 1887, Patrick Joseph P.J. Kennedy married Mary Augusta Hickey, daughter of James Hickey of Cork, Ireland, and Margaret M. Field, also of Ireland. Their son, Joseph Patrick Kennedy, was born on September 6, 1888 in East Boston.
Tau is a protein found in neurons, where it works to stabilize the shape and function of the cell. As part of normal function, proteins in the body fold, unfold and refold into different shapes in order to perform specific functions, and when they are no longer needed, they are broken down and recycled by the cell.
Moussa likened tau to a train trackâ if itâs functioning normally, the train can run. If itâs disrupted, the train canât move debris from one end of the cell to the other. There needs to be a ratio of âgoodâ to âbadâ tau -- the âgoodâ holds the tracks together, but the âbadâ makes it fall apart.