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Then there were the scary side effects. Though rare, some of Neulastaâs serious side effects include acute respiratory distress syndrome (ARDS), severe allergic reactions and fatal splenic rupture. The scariest one for me, however, was the more commonly reported reaction: bone pain.
Neulasta is given once for each cycle of high-dose chemotherapy, at least 24 hours after chemo, and no sooner than 14 days before your next chemo infusion. Neupogen is given in several injections on a daily basis, until your neutrophil counts come back to normal levels.