The Cas9 nuclease and requirements for RNA-guided genome-editing. Cas9 is the nuclease guided by the crRNA and tracrRNA (or trans-activating crRNA) to cleave specific DNA sequences (Deltcheva et al.2011). A guide RNA (gRNA) can be designed to include a hairpin that mimics the tracrRNA-crRNA complex (Jinek et al. 2012).he Cas9 nuclease and requirements for RNA-guided genome-editing. Cas9 is the nuclease guided by the crRNA and tracrRNA (or trans-activating crRNA) to cleave specific DNA sequences (Deltcheva et al. 2011).
Solid Surface Bathroom Countertops: These countertops are made from synthetic materials, so they are manufactured in many colors and styles. The pros of solid surface countertops include the choices, strength and a non-porous surface that cleans up quickly.
Quartz counters are made by combining 93% natural quartz stone with 7% resin binder and some colourant. This creates an extremely hard stone that is stronger that granite or marble. The slab is the same working thickness as other materials, and it is shaped, cut and finished using the same stone-cutting equipment.