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Finally, with further decreases in the levels of CD4 cells, the person develops AIDS. According to the CDC, for an HIV-infected person, some signs that AIDS has developed (known as AIDS-defining conditions) are: The CD4 cell count has decreased to fewer than 200 cells per cubic milliliter of blood.
HIV infects cells in the central nervous system and the immune system. HIV's main target cell is the T helper lymphocyte. These cells play a crucial role in the immune system, by coordinating the actions of other immune system cells. A large reduction in the number of T helper cells seriously weakens the immune system.