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A follow-up test that measures free prostate-specific antigen (free PSA) may be used to see if a prostate biopsy should be done to check for cancer. Free PSA is the percent of prostate-specific antigen that is not attached to proteins in the blood. The lower a man's free PSA percentage, the more likely he is to have prostate cancer. A man with a total PSA between 4 and 10 ng/mL may have a test to find out his free PSA, to see if cancer is likely to be present.
What is PSA? PSA is one of three major factors that are considered when evaluating a manâs particular case of prostate cancer. PSA stands for Prostate Specific Antigen. The word âspecificâ means that this enzyme is produced only by prostate cellsâwhether normal prostate cells or prostate cancer cells. No other cells (lung, intestine, liver, etc.) make PSA. The purpose of PSA is to keep semen (the white substance ejaculated during sexual intercourse) liquefied.