The carrier frequency and incidence of alpha thalassemia vary by the type and population. Carrier frequency of this condition is reported to be the highest in individuals of Southeast Asian, African, West Indian, and Mediterranean descent.
Clitheroe Castle Museum is adjacent to the castle. The castle was listed as a Scheduled Monument on 10 April 1915 (and later, under the Ancient Monuments and Archaeological Areas Act 1979 law).It was Grade I listed on 19 May 1950.t has been suggested that Clitheroe Castle may have been first built before 1086 as there is reference to the  castellatu Rogerii pictaviensis  in the Domesday Book entry for nearby Barnoldswick. However, it is likely the passage refers to another castle.
Conwy Castle. Conwy Castle, a World Heritage Site, is a magnificent fortress in North Wales. Built by James Saint George for King Edward I, it has towered over the medieval town of Conwy ever since.onwy Castle. Conwy Castle, a World Heritage Site, is a magnificent fortress in North Wales. Built by James Saint George for King Edward I, it has towered over the medieval town of Conwy ever since.