cerebral cortex. The outer layer of gray matter that covers the cerebral hemispheres in the brain of many vertebrate animals and is composed of folds of nerve cells and fibers.erebral cortex. The outer layer of gray matter that covers the cerebral hemispheres in the brain of many vertebrate animals and is composed of folds of nerve cells and fibers.
Dopamine blockers and depletors are used to treat conditions that arise from the over-production or increased activity of dopamine. Dopamine blockers work by binding to and blocking the action of dopamine receptors.his prevents the receptors from using the dopamine that is present in the brain or elsewhere in the body. Conversely, dopamine depletors work by preventing dopamine from being stored or released by neurons. There are numerous types of dopamine blockers and depletors.
The Biochemistry of Addiction. Dopamine plays an important role in the reward system. Dopamine is a natural chemical in the brain that sends signals to the limbic system. When introduced into the limbic system, drugs either mimic dopamine or cause an overproduction of it in the brain. The reason normal actions that activate the brain reward system (food, drinking, sex, music, etc.) donât reprogram the brain for addiction is because they produce normal levels of dopamine.