fourthyearmed Senior Member 5+ Year Member. Yes, 3rd year is long, hard, a lot of work, and has tests but I still enjoyed it so much more than the HELL that was 1st and 2nd years. 3rd year involves interaction not just with patients but with other people in the medical field besides your classmates.
The mitotic spindle is the macromolecular machine that segregates chromosomes to two daughter cells during mitosis. The major structural elements of the spindle are microtubule polymers, whose intrinsic polarity and dynamic properties are critical for bipolar spindle organization and function.he mitotic spindle is the macromolecular machine that segregates chromosomes to two daughter cells during mitosis. The major structural elements of the spindle are microtubule polymers, whose intrinsic polarity and dynamic properties are critical for bipolar spindle organization and function.
Some of the spindle fibers extend out and connect to a kinetochore on either side of the centromere. The spindle fibers pull and tug on the kinetochores until all the chromosomes are lined up across the center of the cell. During metaphase, the spindle fibers form a lemon-shaped array. This is called the mitotic spindle.