Hyponatremia is an important electrolyte abnormality with the potential for significant morbidity and mortality. Common causes include medications and the syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Hyponatremia can be classified according to the volume status of the patient as hypovolemic, hypervolemic, or euvolemic.
Design-assist can be implemented on nearly any construction project regardless of type or size. Its benefits include improvements in design efficiency, cost management, speed to market, and constructability. DA is best leveraged when early engagement of certain subcontractors is most beneficial for the project.
The benefits of participating in the MDSAP pilot include: 1  The ability to pilot the implementation of the requirements that are defined in the IMDRF MDSAP Model and provide feedback towards program improvement. 2  Getting an early start at minimizing the regulatory burdens on the medical device manufacturing industry.