Of the 56.4 million deaths worldwide in 2015, more than half (54%) were due to the top 10 causes. Ischaemic heart disease and stroke are the worldâs biggest killers, accounting for a combined 15 million deaths in 2015. These diseases have remained the leading causes of death globally in the last 15 years.
Contraction and Spread of Streptococcus pyogenes. Streptococcus pyogenes is a very common bacteria found in humans. It is very transmissible and can be caught through the air via coughing or sneezing. This form of Strep. illness is referred to as Streptococcal pharyngitis, also known as Strep. throat, which can complicate into Scarlet Fever.
Streptococcus pyogenes possesses a wide variety of virulence factors and can cause severe invasive infections. Most S. pyogenes express surface-located fibronectin-binding proteins as major invasion molecules.. Group A Streptococcus pyogenes is an important gram-positive bacterial pathogen that causes a wide variety of clinical conditions, ranging from pharyngitis to severe invasive infections and necrotizing fasciitis. The reported lethality of severe S. pyogenes infections is high, ranging from 10%â30% [1] .