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No dog received an individual dose of trazodone > 300 mg. The maximum daily dose was 600 mg, which represented a combined twice-daily and asneeded dose in a dog that weighed 36 kg (79.2 lb). For as-needed doses, most clients observed that behavioral effects occurred within 1 to 2 hours of trazodone administration.
Overdose Level of Trazodone. The recommended dosage of Trazodone both for adult and geriatric clients is 150 mg once day. The dosage may be increased to 50 mg every four days or three days. The maximum daily dose may be up to 400 mg for outpatients, while hospitalized patients may take up to 600 mg daily.