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Elephantiasis is a syndrome caused by infection with a nematode parasite called the filarial worm. The parasite is transmitted form human to human via the female mosquito and grows into an adult worm that lives in the lymphatic system of a human.
In areas where filariasis is endemic, the most common cause of elephantiasis is a parasitic disease known as lymphatic filariasis and, in the medical literature, the terms lymphatic filariasis and elephantiasis may be used interchangeably.lephantiasis is caused by obstruction of the lymphatic system, which results in the accumulation of a fluid called lymph in the affected areas. Functioning as part of the immune system, the lymphatic system helps to protect the body against infection and disease.