Compared to certain other plants, peace lilies don't need to be pruned very frequently. However, if, for whatever reason, one or more of your lily's limbs or leaves become brown or wilted, you may want to prune the leaves to keep the plant from wasting energy on the dying appendage.
Accutane is a retinoid, and not related to anti-biotics so the side effects are different. However, the list of potential rare side effects of accutane is long and includes headaches, nausea, muscle pain and depression.
solodyn. My advice for you is to stay on Minocyclin, because the side effects for accutane will only be stronger and worse than the side effects of Minocyclin, but if you want to try accutane and see how the side effects affect you.