Page 1 of 8. Connotation and Denotation. Connotation and Denotation. Connotation and Denotation are two principal methods of describing the meanings of. words. Connotation refers to the wide array of positive and negative associations that. most words naturally carry with them, whereas denotation is the precise, literal definition. of a word that might be found in a dictionary.
Medical Definition of orphan drug. : a drug that is not developed or marketed because its extremely limited use (as in the treatment of a rare disease) makes it unprofitable.
1. opium-an addictive narcotic extracted from seed capsules of the opium poppy. controlled substance-a drug or chemical substance whose possession and use are controlled by law. narcotic-a drug that produces numbness or stupor; often taken for pleasure or to reduce pain; extensive use can lead to addiction.. opium-an addictive narcotic extracted from seed capsules of the opium poppy. controlled substance-a drug or chemical substance whose possession and use are controlled by law. narcotic-a drug that produces numbness or stupor; often taken for pleasure or to reduce pain; extensive use can lead to addiction.