You must submit your correlations or covariances into a com-. puter program to extract your factors. This step is too complex to reasonably be done by hand. There. are a number of diï¬erent extraction methods, including maximum likelihood, principal component, and principal axis extraction. The best method is generally maximum likelihood extraction, unless you. seriously lack multivariate normality in your measures.
However the incidence of malignancy (invasive or in situ) as a cause of PND varies between 1 and 23% depending upon the series studied [3]. A solitary papilloma is not thought to be a pre-malignant lesion [5] and is considered by some to be an aberration rather than a true disease process [6].
A neoplasm can be benign, potentially malignant (pre-cancer), or malignant (cancer). 1  Benign tumors include uterine fibroids and melanocytic nevi (skin moles). 2  They are circumscribed and localized and do not transform into cancer.3  Potentially-malignant neoplasms include carcinoma in situ. Secondary neoplasm refers to any of a class of cancerous tumor that is either a metastatic offshoot of a primary tumor, or an apparently unrelated tumor that increases in frequency following certain cancer treatments such as chemotherapy or radiotherapy.