What is polycystic ovarian syndrome (PCOS)? Polycystic ovarian syndrome, or PCOS, is a condition in which a womanâs levels of the sex hormones estrogen and progesterone are out of balance. This leads to the growth of ovarian cysts (benign masses on the ovaries). PCOS can cause problems with a womenâs menstrual cycle, fertility, cardiac function, and appearance.
For the serious over-pronator who needs maximum support from a shoe. 1  Brooks Beast: Solid motion control without excess weight. 2  Brooks Addiction: Very strong support. 3  Asics Foundation: Gel cushioning with plenty of strong arch support.
Report Abuse. You need to replace shoes every 300 miles, so I would say run at least 30 miles in them before a race, to break them in well. 50 would be optimal, but 30 would be fine. That way you get a week or two to figure out what spots you need to tape or ice pre-race.Good luck in your 5k's!aking the proper care in selecting and breaking in running shoes can mean the difference between a smooth run and a rocky one full of blisters and foot and joint pain. Break in running shoes by running 60 to 70 miles.