The U.S. infant mortality rate generally declined throughout the 20th century, from 100 infant deaths per 1,000 live births in 1900 to 6.89 infant deaths per 1,000 live births in 2000.
hemoglobinopathies are genetic inherited disorders of hemoglobin the oxygen carrying protein of the red blood cells the hemoglobin molecule is composed of four separate polypeptide chains of amino acids two alpha chains and two beta chains as well as four iron bearing heme groups that bind oxygenemoglobinopathies are genetic inherited disorders of hemoglobin the oxygen carrying protein of the red blood cells the hemoglobin molecule is composed of four separate polypeptide chains of amino acids two alpha chains and two beta chains as well as four iron bearing heme groups that bind oxygen
Genetics of Thalassemia. The Inheritance of Thalassemia. Recall that hemoglobin is the protein that is affected in thalassemia. Hemoglobin is made of heme, alpha globins, and beta globins. At least 9 different genes direct the production of heme. Changes in these genes may lead to disorders of heme production, a group of conditions separate from the thalassemias.