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Each of these activities is required during the process of reverse transcription to convert the single-stranded RNA genome into a double DNA copy, which in turn becomes integrated into the host chromosome of the infected cell catalyzed by a second pol gene-encoded enzyme, called integrase.everse Transcriptase. Reverse transcriptase catalyzes the formation of double-stranded deoxyribonucleic acid (DNA) from a single-stranded ribonucleic acid (RNA) genome.
Major Enzymes. The process of DNA replication is catalyzed by a type of enzyme called DNA polymerase (poly meaning many, mer meaning pieces, and âase meaning enzyme; so an enzyme that attaches many pieces of DNA).