1 Down syndrome, usually is caused by an extra copy of chromosome 21 (trisomy 21). Characteristics include decreased muscle tone, asymmetrical skull, slanting eyes and mild to moderate mental retardation.  Edward's syndrome, which is the second most common trisomy after Down syndrome. It is a trisomy of chromosome 18.
Guanxi describes the basic dynamic in personalized networks of influence, and is a central idea in Chinese society.
Zhejiang, formerly romanized as Chekiang, is an eastern coastal province of China. Zhejiang is bordered by the Jiangsu province and the Shanghai municipality to the north, the Anhui province to the northwest, the Jiangxi province to the west, the Taiwan province to the southeast, and the Fujian province to the south. To the east is the East China Sea, beyond which lies the Ryukyu Islands of Japan.