What is polycystic ovarian syndrome (PCOS)? Polycystic ovarian syndrome, or PCOS, is a condition in which a womanâs levels of the sex hormones estrogen and progesterone are out of balance. This leads to the growth of ovarian cysts (benign masses on the ovaries). PCOS can cause problems with a womenâs menstrual cycle, fertility, cardiac function, and appearance.
For the serious over-pronator who needs maximum support from a shoe. 1  Brooks Beast: Solid motion control without excess weight. 2  Brooks Addiction: Very strong support. 3  Asics Foundation: Gel cushioning with plenty of strong arch support.
Same for if you âpoundâ the ground when you run as opposed to having a softer stride. Most pros agree that shoes should be replaced between 300â500 miles of use. After that, they lose maximum support and shock absorption, which may leave you vulnerable to injury. Still, the exact timing is up to how you use them.