Compared to certain other plants, peace lilies don't need to be pruned very frequently. However, if, for whatever reason, one or more of your lily's limbs or leaves become brown or wilted, you may want to prune the leaves to keep the plant from wasting energy on the dying appendage.
Accutane is a retinoid, and not related to anti-biotics so the side effects are different. However, the list of potential rare side effects of accutane is long and includes headaches, nausea, muscle pain and depression.
Accutane, which is currently no longer on the market, was only meant to be used as a last resort to treat acne, but prescriptions of its competitors and generic versions are just as health damaging and are being offered for even acute cases of a few spots.