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(Unipolar is the term used to differentiate the difference between major depression and bipolar.) For example, people with bipolar disorder canât take anti depressants alone as a treatment for the illness due to the danger of mania caused by the anti depressants.
1 Bipolar I Disorder is an illness in which people have experienced one or more episodes of mania. 2  Most people diagnosed with bipolar I will have episodes of both mania and depression, though an episode of depression is not necessary for a diagnosis.eople with bipolar disorder who have psychotic symptoms may be wrongly diagnosed as having schizophrenia. Mania. To be diagnosed with bipolar disorder, a person must have experienced mania or hypomania. Hypomania is a milder form of mania that doesn't include psychotic episodes.