1 Down syndrome, usually is caused by an extra copy of chromosome 21 (trisomy 21). Characteristics include decreased muscle tone, asymmetrical skull, slanting eyes and mild to moderate mental retardation.  Edward's syndrome, which is the second most common trisomy after Down syndrome. It is a trisomy of chromosome 18.
Guanxi describes the basic dynamic in personalized networks of influence, and is a central idea in Chinese society.
The Guangxu Emperor (14 August 1871 â 14 November 1908), personal name Zaitian (Manchu: Dzai-Tiyan), was the eleventh emperor of the Qing dynasty, and the ninth Qing emperor to rule over China. His reign lasted from 1875 to 1908, but in practice he ruled, under Empress Dowager Cixi's influence, only from 1889 to 1898.