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Ankylosing Spondylitis (AS) is a type of progressive arthritis that leads to chronic inflammation of the spine and sacroiliac joints. It can also affect other joints and organs in the body, such as the eyes, lungs, kidneys, shoulders, knees, hips, heart, and ankles.
Unlike ordinary back pain, ankylosing spondylitis (AS) is not caused by physical trauma to the spine. Rather, it is a chronic condition caused by inflammation in the vertebrae (the bones of the spine). AS is a form of spinal arthritis. Although intermittent flare-ups of spinal pain and stiffness are the most common symptoms, the disease can also affect other joints, as well as the eyes and the intestines. In advanced AS, abnormal bone growth in the vertebrae may cause joints to fuse, severely reducing mobility.