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The innervation is supplied by the inferior gluteal nerve, a branch of the sacral plexus (L4-S2). Numerous vessels and nerves run under the gluteus maximus muscle, including the sciatic nerve, the pudendal nerve and the superior gluteal vessels.
The nerve plexus also offers sensory and motor nerves for sections of the pelvis, the entirety of the foot, the back of the thigh, and the majority of the lower legs. The superior nerve starts out in the pelvis and supplies the tensor fasciae latae, the gluteus minimus, and the gluteus medius muscles.