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A histiocytoma is a benign skin tumor that originates in the Langerhans cells, immune cells that function to provide protective immunity to the tissues that are in contact with the outer environment -- the nose, stomach, intestines and lungs, but mainly the skin's surface. histiocytoma is a benign skin tumor that originates in the Langerhans cells, immune cells that function to provide protective immunity to the tissues that are in contact with the outer environment -- the nose, stomach, intestines and lungs, but mainly the skin's surface.
Basically, a pheochromocytoma is a tumor of these catecholamine-secreting cells, and that causes the clinical signs and symptoms we will discuss below. The catecholamine-secreting cells are sometimes referred to as chromaffin cells, and they are found in other areas of the body as well as in the adrenal medulla.Sometimes, pheochromocytomas arise from chromaffin cells that are located outside of the adrenal gland.he catecholamine-secreting cells are sometimes referred to as chromaffin cells, and they are found in other areas of the body as well as in the adrenal medulla. Sometimes, pheochromocytomas arise from chromaffin cells that are located outside of the adrenal gland.