Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. 1  Posaconazole. 2  Probenecid. 3  Pyrimethamine. 4  St John's Wort. 5  Theophylline. 6  Valproic Acid.
Smoking not only has harmful effects on general health but can also increase the risk when having anaesthesia and surgery. Smoking is associated with heart disease, peripheral vascular (blood vessel) disease and multiple types of cancer, including lung, throat, and oesophagus (food tube) and bladder cancer.It can also cause emphysema and chronic bronchitis.mokers have a decreased ability to carry oxygen in the blood, however ceasing smoking for more than 12 hours greatly improves the ability of the blood to carry oxygen. There is also evidence of increased respiratory complications during and after general anaesthesia in children exposed to environmental tobacco smoke.
But all anesthesia has some risk. For example: 1  After general anesthesia heart problems, pneumonia, sore throat, or vomiting can occur. 2  With high doses of local anesthesia, the anesthetic can go into the rest of the body and affect your brain or heart.3  After spinal anesthesia some people get headaches. Know when to stop eating and drinking. 2  If you take any medicines regularly, ask your doctor or nurse about changes to your medicine routine for the day before or the day of your surgery. 3  Try to stay calm. 4  Many people are nervous before they have anesthesia and surgery.