1 Down syndrome, usually is caused by an extra copy of chromosome 21 (trisomy 21). Characteristics include decreased muscle tone, asymmetrical skull, slanting eyes and mild to moderate mental retardation.  Edward's syndrome, which is the second most common trisomy after Down syndrome. It is a trisomy of chromosome 18.
Guanxi describes the basic dynamic in personalized networks of influence, and is a central idea in Chinese society.
Guangxi Province = Wide West. The current province name Guangxi is a contraction of the ancient name Guangnan Xilu, meaning Wide South, West Route, referring to present Guangxi's role as the western route from early China's core lands to the lands to the south.