Poewe W, Seppi K, Fitzer-Attas CJ, Wenning GK, Gilman S, Low PA, et al. Efficacy of rasagiline in patients with the parkinsonian variant of multiple system atrophy: a randomised, placebo-controlled trial.
Bread is good for you, but as with anything we eat too much of anything is bad for you. Notice also if you have bread alot, in the morning you will feel a hole in your stomach, you will be starving in the morning. That's the effect of carbs. But lack of rest and sleep will cause eyebags to droop like bin liners.
High in calories. While this one may seem a bit odd as a slice of bread typically only contains 80-120 calories; however, rarely do we eat bread alone. On every slice there is usually a pad of melted butter, a few tablespoons of peanut butter or a whopping pile of hummus.