The U.S. infant mortality rate generally declined throughout the 20th century, from 100 infant deaths per 1,000 live births in 1900 to 6.89 infant deaths per 1,000 live births in 2000.
hemoglobinopathies are genetic inherited disorders of hemoglobin the oxygen carrying protein of the red blood cells the hemoglobin molecule is composed of four separate polypeptide chains of amino acids two alpha chains and two beta chains as well as four iron bearing heme groups that bind oxygenemoglobinopathies are genetic inherited disorders of hemoglobin the oxygen carrying protein of the red blood cells the hemoglobin molecule is composed of four separate polypeptide chains of amino acids two alpha chains and two beta chains as well as four iron bearing heme groups that bind oxygen
1 Sickle/beta-thalassemia. 2  In this condition, the patient has inherited a gene for hemoglobin S from one parent and a gene for beta-thalassemia from the other. 3  The severity of the condition is determined to a large extent by the quantity of normal hemoglobin produced by the beta-thalassemia gene. Hemoglobin C. Hemoglobin C results from a mutation in the beta globin gene and is the predominant hemoglobin found in people with hemoglobin C disease (a 2 b 2). 2  Hemoglobin C disease is relatively benign, producing a mild hemolytic anemia and splenomegaly.