Page 1 of 8. Connotation and Denotation. Connotation and Denotation. Connotation and Denotation are two principal methods of describing the meanings of. words. Connotation refers to the wide array of positive and negative associations that. most words naturally carry with them, whereas denotation is the precise, literal definition. of a word that might be found in a dictionary.
Medical Definition of orphan drug. : a drug that is not developed or marketed because its extremely limited use (as in the treatment of a rare disease) makes it unprofitable.
Interstitial Lung Disease. EmphyCorp has been granted Orphan Drug status by the FDA to develop N115 for the treatment of Interstitial Lung Disease. The intent of the Orphan Drug Act is to stimulate the research, development, and approval of products that treat rare diseases.