Page 1 of 8. Connotation and Denotation. Connotation and Denotation. Connotation and Denotation are two principal methods of describing the meanings of. words. Connotation refers to the wide array of positive and negative associations that. most words naturally carry with them, whereas denotation is the precise, literal definition. of a word that might be found in a dictionary.
Medical Definition of orphan drug. : a drug that is not developed or marketed because its extremely limited use (as in the treatment of a rare disease) makes it unprofitable.
Some prescription medicines are controlled under the Misuse of Drugs legislation. These medicines are called controlled medicines or controlled drugs.Examples include:1  morphine. 2  pethidine. 3  methadone.ontrolled medicines are classified (by law) based on their benefit when used in medical treatment and their harm if misused. The Misuse of Drugs regulations include five schedules that classify all controlled medicines and drugs.