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Elephantiasis is a syndrome caused by infection with a nematode parasite called the filarial worm. The parasite is transmitted form human to human via the female mosquito and grows into an adult worm that lives in the lymphatic system of a human.
Two nematode species are associated with elephantiasis, Wuchereria bancrofti and Brugia malayi. They are similar in many aspects of their biology. One primary difference is that brugian filariasis is not as widely distributed as is bancroftian filariasis, although the distributions of the two diseases overlap in many areas.