Having the prothrombin mutation increases the risk of developing a DVT (a blood clot in the deep veins, typically the legs) and/or PE (blood clot that travels to the lungs). DVTs are dangerous because they can damage the veins, leading to pain and swelling, and sometimes to disability.
A Clinical Research Associate (CRA), also called a clinical monitor or trial monitor, is a health-care professional who performs many activities related to medical research, particularly clinical trials.
A: By definition, the difference is: PICC is short for peripherally inserted central catheter. It is a central vascular access device inserted into an extremity and advanced in the venous system until the distal tip is positioned in the vena cava.