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Squamous cell carcinoma is the second most common type of skin cancer, after basal cell carcinoma. In the United States, approximately 700,000 cases of squamous cell carcinoma are diagnosed each year and the incidence has been following an upward trend.
Some common types of carcinoma include: 1  Basal cell carcinoma: The most common type of skin cancer. Cancerous cells develop within the basal cell layer of the skin, or the lowest part of the epidermis. 2  Squamous cell carcinoma: The second most common type of skin cancer.