Medicines may be needed when symptoms of sinusitis are severe or do not improve. The goals of treatment with medicine are to: Treat the infection, which is usually caused by bacteria if your symptoms have lasted more than 7 to 10 days. Relieve pressure and pain caused by poor sinus drainage.
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Some of the more serious but rare side effects of nitrofurantoin have been a cause of concern. These include pulmonary reactions, hepatotoxicity, and neuropathy. Pulmonary toxicity. The pulmonary toxicity caused by nitrofurantoin can be categorized into acute, subacute, and chronic pulmonary reactions.