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Syphilis is spread from sexual skin-to-skin contact with someone who has it. You get it when your vulva, vagina, penis, anus, or mouth touches someone's syphilis sores â usually during sex. Syphilis can be spread even if no one cums. The main ways people get syphilis are from having vaginal sex and anal sex. It's less common to get it from having oral sex, but it can happen.
They look for antibodies to the bacterium, or germ, that causes syphilis. Some tests look for the syphilis germ itself. Syphilis is a sexually transmitted infection. That means it is spread through sexual contact: vaginal, anal, or oral sex. Testing is done on blood, body fluid, or tissue samples.