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Syphilis is spread from sexual skin-to-skin contact with someone who has it. You get it when your vulva, vagina, penis, anus, or mouth touches someone's syphilis sores â usually during sex. Syphilis can be spread even if no one cums. The main ways people get syphilis are from having vaginal sex and anal sex. It's less common to get it from having oral sex, but it can happen.
In general, a person can no longer transmit syphilis 24 hours after starting treatment. Some people, however, do not respond to the usual doses of penicillin, so it is important that your health care provider advises individuals on when it is safe for them to commence unprotected sex.