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Hepatitis B vaccine is a vaccine for the prevention of hepatitis B, an infection caused by the hepatitis B virus (HBV) .The vaccine contains one of the viral envelope proteins, hepatitis B surface antigen (HBsAg). It is produced by yeast cells, into which the genetic code for HBsAg has been inserted.he vaccine contains one of the viral envelope proteins, hepatitis B surface antigen (HBsAg).
Vaccine Administration. Hepatitis B vaccine (see Table 3-04) is usually administered as a 3-dose series on a 0-, 1-, 6-month schedule to achieve immunity. The second dose should be given â¥1 month after the first dose; the third dose should be given â¥2 months after the second dose and â¥4 months after the first dose.