Page 1 of 8. Connotation and Denotation. Connotation and Denotation. Connotation and Denotation are two principal methods of describing the meanings of. words. Connotation refers to the wide array of positive and negative associations that. most words naturally carry with them, whereas denotation is the precise, literal definition. of a word that might be found in a dictionary.
Medical Definition of orphan drug. : a drug that is not developed or marketed because its extremely limited use (as in the treatment of a rare disease) makes it unprofitable.
adjective. noun. The definition of orphan is a child or something related to a child who's lost their parents. An example of orphan is a home for children without parents; an orphan home. An orphan is defined as a child whose parents have died. An example of an orphan is a little girl whose mother and father died in a car accident.