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Hepatitis B vaccine is a vaccine for the prevention of hepatitis B, an infection caused by the hepatitis B virus (HBV) .The vaccine contains one of the viral envelope proteins, hepatitis B surface antigen (HBsAg). It is produced by yeast cells, into which the genetic code for HBsAg has been inserted.he vaccine contains one of the viral envelope proteins, hepatitis B surface antigen (HBsAg).
Adults who seek protection from hepatitis B virus infection may receive a 3-dose series of single-antigen hepatitis B vaccine (HepB) (Engerix-B, Recombivax HB) at 0, 1, and 6 months. Adults may also receive a combined hepatitis A and hepatitis B vaccine (HepA-HepB) (Twinrix) at 0, 1, and 6 months.