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Elephantiasis is a syndrome caused by infection with a nematode parasite called the filarial worm. The parasite is transmitted form human to human via the female mosquito and grows into an adult worm that lives in the lymphatic system of a human.
1 Lymphatic filariasis is caused by the worms Wuchereria bancrofti, Brugia malayi, and Brugia timori. 2  These worms occupy the lymphatic system, including the lymph nodes; in chronic cases, these worms lead to the disease elephantiasis. Lymphatic filariasis is caused by the worms Wuchereria bancrofti, Brugia malayi, and Brugia timori. 2  These worms occupy the lymphatic system, including the lymph nodes; in chronic cases, these worms lead to the disease elephantiasis.