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(Unipolar is the term used to differentiate the difference between major depression and bipolar.) For example, people with bipolar disorder canât take anti depressants alone as a treatment for the illness due to the danger of mania caused by the anti depressants.
A diagnosis of bipolar spectrum disorder may be made if you meet any of the following descriptions: 1  Bipolar I: Quite simply, this diagnosis is made if youâve ever had a manic episode. Even just once. 2  Bipolar II: In this classification, the individual âonlyâ has hypomanias, as opposed to full-blown mania.