1 Many skin conditions itch, including eczema (dermatitis), psoriasis, scabies, lice, chickenpox and hives. 2  The itching usually affects specific areas and is accompanied by other signs, such as red, irritated skin or bumps and blisters. 3  Internal diseases. Skin conditions and rashes. 2  Many skin conditions itch, including eczema (dermatitis), psoriasis, scabies, lice, chickenpox and hives. 3  The itching usually affects specific areas and is accompanied by other signs, such as red, irritated skin or bumps and blisters. 4  Internal diseases.
Restless legs syndrome. Restless legs syndrome (RLS) is a nervous system problem that causes you to feel an unstoppable urge to get up and pace or walk. You feel uncomfortable unless you move your legs. Moving stops the unpleasant feeling for a short time.
In the United States, restless legs syndrome may affect up to 10% of people. It is particularly common among people older than 50. Most people with restless legs syndrome also have symptoms of periodic limb movement disorder, but most people with periodic limb movement disorder do not have restless legs syndrome. What causes these disorders is unknown. But one third or more of people with restless legs syndrome have family members with the syndrome.