Having the prothrombin mutation increases the risk of developing a DVT (a blood clot in the deep veins, typically the legs) and/or PE (blood clot that travels to the lungs). DVTs are dangerous because they can damage the veins, leading to pain and swelling, and sometimes to disability.
A Clinical Research Associate (CRA), also called a clinical monitor or trial monitor, is a health-care professional who performs many activities related to medical research, particularly clinical trials.
LCI and LCA should not be confused with life cycle costing. LCC is another life cycle approach (i.e, cradle to grave) but it looks at the direct monetary costs involved with a product or service and not environmental impact.