Crowns may be temporary or permanent and may be made out of materials such as porcelain, resin, or metal. Dentures Dentures, removable replacements for missing teeth, come in two types: partial and complete dentures. Dental implants and bridges are suitable alternatives to dentures.
Investigational Drugs and Devices (IND/IDE) Overview. As defined by the Food and Drug Administration (FDA), an IND, or investigational new drug application, is a request for authorization from the FDA to administer an investigational drug or biological product to humans.
Abstract. Purpose: Intestinal neuronal dysplasia (IND) is a disease of the enteric nervous system, which clinically resembles Hirschsprung's disease. The authors reviewed their experience of IND over an 8-year period.Methods: Between 1992 and 1999, 418 patients underwent rectal suction biopsy for persistent constipation.wenty-nine of the 33 patients with IND were diagnosed purely on rectal suction biopsy findings; 4 children required an additional full-thickness biopsy to make the diagnosis. There were 26 male and 7 female patients. Their ages on presentation ranged from 1 day to 10 years.