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From Wikipedia, the free encyclopedia. Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction.
Water pills (aka diuretics) are the oldest and best studied of the drugs used to treat high blood pressure (aka hypertension).Diuretics help the kidneys flush extra water and salt from your body and decrease blood volume to lower pressure. There are three types of diuretics: thiazide, loop and potassium-sparing.n the years since water pills were the drugs of choice for hypertension, the pharmaceutical companies have developed a variety of medicines to keep your pressure in check in ways that are different from the mechanism of diuretics.