Pathogenic mutation. p-a rare allele that exist at a frequency of less than .01 in the human population. v- a change in DNA sequence that may or may not be pathogenic. patho- change in DNA sequence that has an effect on the encoded protein of gene expression that results in disease.
In the fall of 1791, Washington learned of the newly patented automated milling system invented by Oliver Evans. Evans received U.S. Patent #3 for his groundbreaking system, which moved wheat and flour throughout the mill without the need of manual labor. Washington purchased a license for the patent and had the milling system installed in his gristmill. Today, this milling system is faithfully interpreted, fully-functioning, and open to guests on a seasonal basis.
The Lowell System Not all mill owners followed this system. Francis Cabot Lowell, a businessman from New England, developed a very different approach. His ideas completely changed the textile industry in the Northeast. The Lowell system was based on water- powered textile mills that employed young, unmarried women from local farms. The sysâ¬ tem included a loom that could both spin thread and weave cloth in the same mill. Lowell constructed boardinghouses for the women. Boardinghouse residents were given a room and meals along with their jobs.