b. PT/OT/SPL services performed, by a qualified clinician employed by a physician/NPP or physician/NPP group without a Medicare NPI should be reported to Medicare under the physicians/NPPs Medicare NPI, with an appropriate HCPCS/CPT code and the appropriate therapy modifier (GN, GO, GP).
ity.18,19 The Abl SH2 domain forms an extensive interaction interface with the C-terminal lobe of the kinase domain that is stabilized by an interlocking network of hydrogen bonds (Fig. 2).18 Due to the different relative orientation of the 2 kinase lobes in Src and Abl, the SH2 domain approaches the kinase domain much closer in Abl (Fig. 2). The SH2âC-
The role of these local sequence elements in the specificity of protein kinases has been extensively studied with short peptide substrates, which resemble the amino acid sequence of the phosphorylatable sites in substrate proteins, but allow more explicit kinetic study of the phosphorylation reaction, and considerable amount of data has been obtained about the variation of the local sequence specificity of different protein kinases [4].