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In reviewing the causes of endometriosis, it is important to first understand the regular menstrual cycle and how hormones in the body affect the menstrual cycle and the uterus itself. 1  The endometrium is the inner layer of uterine tissue that is shed during menstruation. The thickness of the endometrial layer is related to the egg-producing (ovulatory) cycle and the hormonal levels that regulate this cycle. 2  The endometrium is at its thinnest immediately following menstruation and thickens during the first two weeks of the menstrual cyle.
Menstruation describes the female period. The menstruation cycle begins when a woman gets her periods. The menstrual blood which leaves her body are products shed from the uterus (the uterine lining also called the endometrium). During the remainder of the menstrual cycle the uterine lining regrows.ay 1 of the menstrual cycle coincides with the start of a womanâs period (menstrual bleeding) in which the uterus sheds the lining (endometrium) built up in the previous menstrual cycle. The lining of the uterus is regrown during each menstrual cycle.