Keytruda is given by intravenous (IV) infusion every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months. It is currently a non-preferred brand, specialty medication on standard NPS formularies and carries an average wholesale price (AWP) of $515.79 per day. FDA Safety Update
Tears come from the lacrimal gland. And it's found in the outer part of the upper eye. When excess tears are produced, they drain into small ducts to the nasal cavity. And if you have too many tears to drain, they'll spill out of your eyes. There's an anatomical reason why crying makes your nose run.
Tears are normally discharged through your tear ducts and through evaporation. If your tears do not contain the right balance of water, salt, and oils, your eyes can become too dry. The resulting irritation causes an overproduction of tears that spill out through your tear ducts.