There are a few problems with the common form of Tianeptine, the sodium salt. For one, it is very hygroscopic. This makes handling and storage a pain. More importantly, its short half life and pharmacodynamic properties make dosing required up to 3 times a day.
A dull, sickly yellow began to obscure the sky, and the water, from a beautiful blue, turned a slate color and ran along the sides of the vessel with a hissing sound as though the sullen waves would ask nothing better than to suck the craft down into their depths.
profound. That is obscure which the eye or the mind can not clearly discern or see through, whether because of its own want of transparency, its depth or intricacy, or because of mere defect of light.