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Medical Definition of Karyocyte. Karyocyte: Any cell that possesses a nucleus. A neuron (nerve cell) is a karyocyte; it has a nucleus. A mature erythrocyte (red blood cell) is not a karyocyte; it lacks a nucleus. The term karyocyte is made up of kary- from the Greek karyon meaning nut or kernel + -cyte from the Greek kytos meaning a hollow vessel = a hollow vessel (a cell) containing a nut or kernel (a nucleus).
A histiocyte is a normal immune cell that is found in many parts of the body especially in the bone marrow, the blood stream, the skin, the liver, the lungs, the lymph glands and the spleen. In histiocytosis, the histiocytes move into tissues where they are not normally found and cause damage to those tissues. These proliferating immune cells may form tumors, which can affect various parts of the body.