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Standing is a natural human posture and by itself poses no particular health hazard. However, working in a standing position on a regular basis can cause sore feet, swelling of the legs, varicose veins, general muscular fatigue, low back pain, stiffness in the neck and shoulders, and other health problems.
When you stand up from lying down or sitting, a small momentary dip in blood pressure occurs in the first few seconds. This occurs because gravity causes about 0.5 to 1.0 liters of blood to pool in your lower body.