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One common cause of muscle aches and pain is fibromyalgia, a condition that causes tenderness in your muscles and surrounding soft tissue, sleep difficulties, fatigue, and headaches.
Voila! Thatâs your muscle knot right there, and the effect can be anything from mild discomfort to intense pain. Even if we arenât 100% sure what causes muscle knots, we do know for sure how to identify them.Muscle knots are: 1  Pain that occurs in the fascia or skeletal muscle.2  Nodules or banded muscle that can be felt when palpating the point. 3  Reproducible when the trigger point is palpated.oila! Thatâs your muscle knot right there, and the effect can be anything from mild discomfort to intense pain. Even if we arenât 100% sure what causes muscle knots, we do know for sure how to identify them.