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Ulcerative colitis causes swelling in the large intestine and can lead to cramping, diarrhea, and more. Celiac disease Celiac disease, which is an intestinal reaction to gluten, can cause gas, diarrhea, bloating, and weight loss.
1 There are numerous causes of colitis including infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis.  diarrhea, with or without blood in the stool (one of the hallmark symptoms of colitis).