The mechanism of action of the mammalian carbonic anhydrase has been studied in depth. The enzyme employs a two-step mechanism: in the first step, there is a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide; in the second step, the active site is regenerated by the ionisation of the zinc-bound water molecule and the removal of a proton from the active site.
Bio. 1  Born Janick âJanâ Gers on January 27, 1957. 2  Joined Iron Maiden in 1990. 3  Formerly of Gillian, White Spirit.
3. Pearl Wojtalewicz 3. Teodozia Wojtalewicz Born 29 May 1870 in Gostycyn, Bydgoszcz, Poland Died 5 Aug 1955 in Gostycyn, Bydgoszcz, Poland Married Jan Pliszka Born 29 Mar 1871 in Gostycyn, Bydgoszcz, Poland. Died 22 Dec 1956 in Gostycyn, Bydgoszcz, Poland.