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Standing is a natural human posture and by itself poses no particular health hazard. However, working in a standing position on a regular basis can cause sore feet, swelling of the legs, varicose veins, general muscular fatigue, low back pain, stiffness in the neck and shoulders, and other health problems.
When you stand your circulation has to make adjustments. Your body is a fluid filled container. Blood naturally gravitates to your legs. When you stand, automatic responses mediated by the sympathetic nervous system (adrenaline), the heart, veins and arteries come into play.