The mechanism of action of the mammalian carbonic anhydrase has been studied in depth. The enzyme employs a two-step mechanism: in the first step, there is a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide; in the second step, the active site is regenerated by the ionisation of the zinc-bound water molecule and the removal of a proton from the active site.
Bio. 1  Born Janick âJanâ Gers on January 27, 1957. 2  Joined Iron Maiden in 1990. 3  Formerly of Gillian, White Spirit.
DIE ANTWOORD on a drive through Green Point with Taxijam. Die Antwoord is a zef rap-rave crew from Cape Town, South Africa.The crew is Ninja, Yo-landi Vi$$er and DJ Hi-Tek.Visit: http://www.dieantwoord.com/.IE ANTWOORD on a drive through Green Point with Taxijam. Die Antwoord is a zef rap-rave crew from Cape Town, South Africa.