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Uremia or uraemia (see spelling differences) can be translated as  urea in the blood.Urea is one of the primary components of urine. It can be defined as an excess of amino acid and protein metabolism end products, such as urea and creatinine, in the blood that would be normally excreted in the urine.The Uremic Syndrome can be defined as the terminal clinical manifestation of kidney failure (also called renal failure).It is the signs, symptoms and results from laboratory tests which result from inadequate excretory, regulatory and endocrine function of the kidneys.he Uremic Syndrome can be defined as the terminal clinical manifestation of kidney failure (also called renal failure). It is the signs, symptoms and results from laboratory tests which result from inadequate excretory, regulatory and endocrine function of the kidneys.
One of the waste products of protein metabolism is ammonia. Too much ammonia can be toxic and harmful to the body. Enzymes in the urea cycle convert this toxic ammonia into a nontoxic substance called urea, which can be eliminated from the body.1, 2.ne of the waste products of protein metabolism is ammonia. Too much ammonia can be toxic and harmful to the body. Enzymes in the urea cycle convert this toxic ammonia into a nontoxic substance called urea, which can be eliminated from the body. 1, 2.