Marijuana, Memory, and the Hippocampus. Image by the NIDA. Distribution of cannabinoid receptors in the rat brain. Brain image reveals high levels (shown in orange and yellow) of cannabinoid receptors in many areas, including the cortex, hippocampus, cerebellum, and nucleus accumbens (ventral striatum).
MSM is used to help treat literally dozens of illnesses, painful symptoms and diseases â and, yes, itâs been called a âmiracle supplementâ for all it does. (1, 2) So what is an MSM supplement exactly, and do you need to take one? Letâs find out.
That's not an easy question to answer because there's not a lot of research on the long-term effects of the dietary supplement called methylsulfonylmethane (MSM). MSM is formed using dimethylsulfoxide (DMSO), an organic form of sulfur that's also used as a dietary supplement.Animals observed for 90 days on a daily dose of MSM five to seven times greater than what's typically used in people had no serious problems.Stomach upset, diarrhea and headache have been reported in human trials of MSM lasting up to 12 weeks.However, people taking a placebo also reported similar symptoms. Since little is known about the long-term safety of MSM, it's no surprise that the efficacy also is unclear.tomach upset, diarrhea and headache have been reported in human trials of MSM lasting up to 12 weeks. However, people taking a placebo also reported similar symptoms. Since little is known about the long-term safety of MSM, it's no surprise that the efficacy also is unclear.