The Patch is created in the gyre of the North Pacific Subtropical Convergence Zone. The Great Pacific garbage patch was predicted in a 1988 paper published by the National Oceanic and Atmospheric Administration (NOAA) of the United States. The prediction was based on results obtained by several Alaska-based researchers between 1985 and 1988 that measured neustonic plastic in the North Pacific Ocean.
Bovine Spongiform Encephalopathy (BSE), or Mad Cow Disease. BSE (bovine spongiform encephalopathy) is a progressive neurological disorder of cattle that results from infection by an unusual transmissible agent called a prion. The nature of the transmissible agent is not well understood. Currently, the most accepted theory is that the agent is a modified form of a normal protein known as prion protein.
Cushingâs disease is a specific type of Cushingâs syndrome caused by a pituitary tumor leading to excessive production of ACTH (adrenocorticotropic hormone). Excessive ACTH stimulates the adrenal cortex to produce high levels of cortisol, producing the disease state. Cushing's disease due to excess ACTH may also result in hyperpigmentation. This is due to Melanocyte-Stimulating Hormone production as a byproduct of ACTH synthesis from Pro-opiomelanocortin (POMC).