Medical Definition of DISABLE. : to deprive of a mental or physical capacity. Dictionary: Definition of disable. Thesaurus: All synonyms and antonyms for disable.
While the effects of Vicodin last around 4 hours, traces of the drug can remain in your system for up to 72 hours. In some adults you can still find traces of the drug in your system after 5 days.
Factors That Influence How Long Vicodin Stays in Your System. 1  Dose: If you take a higher dose, it tends to stay in the system for a longer duration. 2  Frequency of Use: When you use more frequently, it may accumulate in the body tissues. 3  Individual Metabolism: The levels of the liver enzymes determine how much of the drug gets metabolized.