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Medical Definition of Karyocyte. Karyocyte: Any cell that possesses a nucleus. A neuron (nerve cell) is a karyocyte; it has a nucleus. A mature erythrocyte (red blood cell) is not a karyocyte; it lacks a nucleus. The term karyocyte is made up of kary- from the Greek karyon meaning nut or kernel + -cyte from the Greek kytos meaning a hollow vessel = a hollow vessel (a cell) containing a nut or kernel (a nucleus).
The term macrocytic is from Greek words meaning large cell. A macrocytic class of anemia is an anemia in which the red blood cells are larger than their normal volume. The normal erythrocyte volume in humans is about 80 to 100 femtoliters. In metric terms the size is given in equivalent cubic micrometers. The condition of having erythrocytes which are too large, is called macrocytosis. In contrast, in microcytic anemia, the erythrocytes are smaller than normal. In a macrocytic anemia, the larg