In summary, we have shown the inhibitory effects of Bcl-2 family on the ceramide-mediated apoptotic pathway in glioma cells. Bcl-2 is considered to act not only downstream of ceramide to inhibit cytochrome c release followed by caspase activation, but also upstream of or at SMase to prevent ceramide generation.igure 3 Effects of Bcl-2 or Bax overexpression on ceramide formation and neutral sphingomyelinase activation in etoposide-treated C6 cells. C6/Neo (), C6/Bcl-2 (), and C6/Bax () cells were treated with 40 M etoposide for indicated periods.
Hawaii, which has the highest-paid waiters and waitresses in the country (mean wage: $13.91/hour) has a minimum wage of $7.00 for tipped employees.
How much do hosts and hostesses make? Since hosts and hostesses usually don't get any tips, they get paid more per hour than waiters or waitresses do. On average, hosts and hostesses make $8.42 an hour, but depending on the type of restaurant where you work, you could make upwards of $12 an hour. If you're really lucky, you'll also get a share of the tips waiters and waitresses make-typically between three and five percent-and an employee discount on your meals.