TALKEETNA, Al. (KTUU) - A cat named Stubbs has been the mayor of Talkeetna, Alaska for nearly all of his life. It's been that way for more than a decade in the small tourist town that boasts nearly 900 residents.
DAT is an integral membrane protein that removes dopamine from the synaptic cleft and deposits it into surrounding cells, thus terminating the signal of the neurotransmitter. Dopamine underlies several aspects of cognition, including reward, and DAT facilitates regulation of that signal.
Synapses are composed of three main parts: 1  The presynaptic ending that contains neurotransmitters. 2  The synaptic cleft between the two nerve cells. 3  The postsynaptic ending that contains receptor sites.