What causes wrinkled peeling fingertips? If you have fingertips peeling and wrinkling, you could be suffering from nerve insufficiency, occupational exposure or even diabetes. Peeling is one of the most common signs, usually visible on the toes and fingers.
Hypothyroidism occurs when your thyroid does not produce enough hormones, which can result in a slow metabolism marked by weight gain, fatigue and sluggishness. If you gain weight, your body will not effectively make energy from food and may contribute to a slowed metabolism.
Some drugs can slow down your metabolism. These include many antidepressants and certain antipsychotics doctors use to treat schizophrenia. Many other medications, like those that slow the heart rate, also can have that effect. What you can do: Let your doctor know if you think your prescriptions might be a problem.