Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
A roundabout, also called a traffic circle, road circle, rotary, rotunda or island, is a type of circular intersection or junction in which road traffic flows almost continuously in one direction around a central island. So-called modern roundabouts require entering traffic to give way to traffic already in the circle and optimally observe various design rules to increase safety. Compared to stop signs, traffic signals, and earlier forms of roundabouts, modern roundabouts reduce the likelihood