Here in St. Louis, we take our food seriously. You may be surprised to learn that some of the countryâs best kept culinary secrets originated right here in the Gateway City. Partners
Novobiocin: an antibiotic obtained from an actinomycete and used to treat infections by gram-positive bacteria. Source: WordNet 2.1. Novobiocin: Novobiocin is one of aminocoumarin antibiotics that were produced by the actinomycete Streptomyces nivens.
Mupirocin, an antibiotic, is used to treat impetigo as well as other skin infections caused by bacteria. It is not effective, however, against fungal or viral infections. Unlike other antibiotics which act on either bacterial DNA or the cellular walls of bacteria, mupirocin blocks the activity of an enzyme called isoleucyl-tRNA synthetase within the bacteria. This enzyme is necessary in order for the bacteria to make proteins. Without the ability to make proteins, the bacteria dies.