The mechanism of action of the mammalian carbonic anhydrase has been studied in depth. The enzyme employs a two-step mechanism: in the first step, there is a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide; in the second step, the active site is regenerated by the ionisation of the zinc-bound water molecule and the removal of a proton from the active site.
Bio. 1  Born Janick âJanâ Gers on January 27, 1957. 2  Joined Iron Maiden in 1990. 3  Formerly of Gillian, White Spirit.
Jan 07 In the year 1858 birth of eliezer Ben-Yehuda, key figure in the revival of Hebrew as a spoken language (d. 1922). Jan 10 In the year 1858 birth of heinrich Zille, German illustrator and photographer (d. 1929). Jan 11 Harry Gordon Selfridge, American retailer (d. 1947) was born in the year 1858.Jan 13 On this day in history birth of oskar Minkowski, Biologist (d.1931). Jan 15 Giovanni Segantini, Italy, painter was born in the year 1858.an 03 In the year 1858 rachel, [Elisabeth Rachel-Felix], FÃ©lix fr/singer (Actress), muse dies at. 36 jan 05 gustaf Af, Geijerstam swedish (Author boken Om) lillebror in the year. 1858 jan 05 in the year 1858 JOHANN Jwafk radetzky Von, Radetz austr/earl field, marshal dies at. 91