(See Pathogenesis of metabolic alkalosis and Clinical manifestations and evaluation of metabolic alkalosis and Treatment of metabolic alkalosis.) INTRACELLULAR SHIFT OF HYDROGEN. Metabolic alkalosis can be generated by a shift of hydrogen ions into the cells. This most often occurs in patients with potassium deficits and hypokalemia. This may be an important pathophysiologic mechanism in patients with metabolic alkalosis due to vomiting or nasogastric suction [7].
An estimated 30,000 to 40,000 people were executed by guillotine during the Reign of Terror. Although many were true criminals and threats to the Committee of Public Safety, many of these people were killed merely for not being supportive enough of the revolution.
Cause of End of the Reign of Terror and the rise of the Directory. The leadership of the committee turned on each other and by 1794, Marat, Robespierre, and Danton were dead, the last two killed as enemies of the revolution. The radical phase ran its course and the people wanted stability.