Dysfunction in the sacroiliac joint, also called the SI joint, can sometimes cause lower back and/or leg pain. Leg pain from sacroiliac joint dysfunction can be particularly difficult to differentiate from radiating leg pain caused by a lumbar disc herniation (sciatica) as they can feel quite similar.
Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the bodyâs immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary between people and may be mild to severe.
Lupus -- also known as systemic lupus erythematosus -- is a disease of the immune system. Normally, the immune system protects the body from infection. In lupus, however, the immune system inappropriately attacks tissues in various parts of the body.This abnormal activity leads to tissue damage and illness. Kidneys. 2  Kidney involvement in people with lupus can be life threatening and may occur in up to half of those with lupus. 3  Kidney problems are more common when someone also has other lupus symptoms, such as fatigue, arthritis, rash, fever, and weight loss.