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In reviewing the causes of endometriosis, it is important to first understand the regular menstrual cycle and how hormones in the body affect the menstrual cycle and the uterus itself. 1  The endometrium is the inner layer of uterine tissue that is shed during menstruation. The thickness of the endometrial layer is related to the egg-producing (ovulatory) cycle and the hormonal levels that regulate this cycle. 2  The endometrium is at its thinnest immediately following menstruation and thickens during the first two weeks of the menstrual cyle.
This lining is known as the endometrium and it provides nourishment for the embryo during the very early days of life. Otherwise, the lining of the uterus is shed each month, resulting in a flow of blood lasting for several days.This is known as the menstrual flow, menstruation or the monthly period.he uterus sits centrally in the pelvis supported by strong fibrous structures called ligaments. The uterine muscle wall expands greatly during pregnancy and strong contractions of this muscle wall during childbirth give rise to the pains of labour.