Pathogenic mutation. p-a rare allele that exist at a frequency of less than .01 in the human population. v- a change in DNA sequence that may or may not be pathogenic. patho- change in DNA sequence that has an effect on the encoded protein of gene expression that results in disease.
In the fall of 1791, Washington learned of the newly patented automated milling system invented by Oliver Evans. Evans received U.S. Patent #3 for his groundbreaking system, which moved wheat and flour throughout the mill without the need of manual labor. Washington purchased a license for the patent and had the milling system installed in his gristmill. Today, this milling system is faithfully interpreted, fully-functioning, and open to guests on a seasonal basis.
This decreased the amount of manual labor needed. In 1764, a British carpenter and weaver named James Hargreaves invented an improved Spinning Jenny, a hand-powered multiple spinning machine that was the first machine to improve upon the spinning wheel.ames Hargreaves' version of the Spinning Jenny had a single wheel that controlled eight spindles which created a weave that used eight threads.This enhancement of the spinning wheel required less time needed to create textiles.