While lysine in the diet is considered safe, excessive doses may cause gallstones. There have also been reports of renal dysfunction, including Fanconi syndrome and renal failure. Talk to your doctor before taking supplemental lysine if you have kidney disease, liver disease, or if you are pregnant or breastfeeding.
Well I dont know about off premise sales, but on premise runs about like this...these are the general cost of sales numbers. Liquor 13%-17%. Beer (bottles)26%-31%. Beer (draft) 18%-26%. Wine-30%-47%. So the gross margin would be the reverse. Liquor 83%-87%.
That's nearly twice what the state raked in from alcohol tax revenue during that same time. In the United States, sales of legal marijuana hit $2.7 billion last year, up from $1.5 billion in 2013, according to cannabis investment and research firm ArcView Group.