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Venous Insufficiency. Venous insufficiency, also know as venous reflux, is the impaired return of venous blood from the legs and feet, often manifesting as varicose veins, swollen ankles, aching legs, skin changes or venous ulcers. In many cases, venous insufficiency is the result of over-dilation of the venous vessels in the legs.
1 There are two systems of veins in the leg: superficial and deep. 2  If a blood clot occurs in a deep vein (deep venous thrombosis), it causes a damming effect, and blood is trapped behind the blockage. 3  This causes redness, swelling, warmth, and pain in the affected area.4  Calf pain and swelling are common symptoms. Veins return blood from the legs to the heart. 2  There are two systems of veins in the leg: superficial and deep. 3  If a blood clot occurs in a deep vein (deep venous thrombosis), it causes a damming effect, and blood is trapped behind the blockage. 4  This causes redness, swelling, warmth, and pain in the affected area.