Crowns may be temporary or permanent and may be made out of materials such as porcelain, resin, or metal. Dentures Dentures, removable replacements for missing teeth, come in two types: partial and complete dentures. Dental implants and bridges are suitable alternatives to dentures.
Investigational Drugs and Devices (IND/IDE) Overview. As defined by the Food and Drug Administration (FDA), an IND, or investigational new drug application, is a request for authorization from the FDA to administer an investigational drug or biological product to humans.
Studies using a drug that has not been approved by the Food and Drug. Administration (FDA) or for indications not in the approved labeling. may require ï¬ling an Investigational New Drug (IND) application with. the FDA. If a study meets speciï¬c regulatory exemption criteria, then an. IND may not be needed.