Dysfunction in the sacroiliac joint, also called the SI joint, can sometimes cause lower back and/or leg pain. Leg pain from sacroiliac joint dysfunction can be particularly difficult to differentiate from radiating leg pain caused by a lumbar disc herniation (sciatica) as they can feel quite similar.
Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the bodyâs immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary between people and may be mild to severe.
This detailed fact sheet is an overview of the epidemiology of systemic lupus erythematosus (SLE). For more basic information for individuals with general questions about lupus, please visit the lupus basic fact sheet. Lupus. Lupus is an autoimmune disease that triggers inflammation in different tissues of the body. Autoimmune diseases happen when the bodyâs immune system attacks its own tissues. The most common type of lupus is systemic lupus erythematosus (SLE), which affects different parts of the body including internal organs. Systemic Lupus Erythematosus (SLE) What is SLE? SLE, a type of lupus, is an autoimmune disease in which the immune system attacks its own tissues. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels, and can cause widespread inflammation and tissue damage in the affected organs.