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Fluocinonide is a topical steroid cream that is used to treat severe skin conditions such as eczema. Read more about fluocinonide topical creams online at Patient Fluocinonide is a topical steroid cream that is used to treat severe skin conditions such as eczema.
OBJECTIVE: The purpose of this study was to evaluate the efficacy and safety of calcipotriene ointment 0.005% versus fluocinonide ointment 0.05% in the treatment of plaque psoriasis... CONCLUSION: Calcipotriene was superior to fluocinonide in the treatment of plaque psoriasis.he active component is the corticosteroid fluocinonide, which is the 21-acetate ester of fluocinolone acetonide and has the chemical name pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)],(6Î±,11Î²,16Î±)-.