TALKEETNA, Al. (KTUU) - A cat named Stubbs has been the mayor of Talkeetna, Alaska for nearly all of his life. It's been that way for more than a decade in the small tourist town that boasts nearly 900 residents.
DAT is an integral membrane protein that removes dopamine from the synaptic cleft and deposits it into surrounding cells, thus terminating the signal of the neurotransmitter. Dopamine underlies several aspects of cognition, including reward, and DAT facilitates regulation of that signal.
Excitatory synapses. The neurotransmitter at excitatory synapses depolarizes the postsynaptic membrane (of a neuron in this diagram). 1  Binding of acetylcholine to its receptors on the postsynaptic cell opens up ligand-gated sodium channels. 2  These allow an influx of Na + ions, reducing the membrane potential. Noradrenaline (also called norepinephrine). 2  Released by postganglionic neurons of the sympathetic branch of the autonomic nervous system. 3  Also used at certain synapses in the CNS. 4  Dopamine. 5  Used at certain synapses in the CNS.