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Kidney failure. High blood pressure is one of the most common causes of kidney failure. That's because it can damage both the large arteries leading to your kidneys and the tiny blood vessels (glomeruli) within the kidneys. Damage to either makes it so your kidneys can't effectively filter waste from your blood.
The kidneys help to regulate the blood pressure by increasing (when blood pressure falls) or decreasing (when blood pressure rises) the blood volume, and also by the renin-angiotensin system described above. The kidney-fluid system is the main method of the long-term control of blood pressure. In addition to the RAAS sytem, renal blood flow is regulated by: Pressure Diuresis: As arteriolar blood pressure increases, so flow through the kidneys also increases and this increases filtration rate and urinary output.