Definition of inference for English Language Learners. : 1  the act or process of reaching a conclusion about something from known facts or evidence. : 2  a conclusion or opinion that is formed because of known facts or evidence.
Causes of Clogged Arteries. There are many substances and properties that can circulate with the blood, including cholesterol, calcium, fat, fibrin and cellular waste. When these substances accumulate on the inner walls of the arteries, they turn into plaque buildup.
In response to plaque buildup, cells in your artery walls multiply and secrete additional substances that can worsen the state of clogged arteries. As plaque deposits grow, a condition called atherosclerosis results.