Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
A highway is a major road, paved, and most of the time maintained by federal or local governments. Basically your normal main roads. A freeway/expressway (I believe they are fairly interchangeable) is a major road usually with more than 2 lanes on each side and is free for most passenger cars and light trucks. Some charge a fee for trucks or enforce a lower speed limit for trucks over a certain weight or axle count.