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You can use oregano oil in a variety of ways, depending on your health needs: 1  Topically for athlete's foot or nail fungus. 2  Inhaled to treat sinus infections or colds. 3  Under your tongue to help treat infections or parasites.
Side Effects of Oil of Oregano. Oil of oregano is extracted from the leaves of Origanum vulgare. Overview. Herbalists prize oil of oregano, extracted from the leaves of Origanum vulgare, for its medicinal properties, including the ability to inhibit the growth of bacteria, fungi and viruses.