TALKEETNA, Al. (KTUU) - A cat named Stubbs has been the mayor of Talkeetna, Alaska for nearly all of his life. It's been that way for more than a decade in the small tourist town that boasts nearly 900 residents.
DAT is an integral membrane protein that removes dopamine from the synaptic cleft and deposits it into surrounding cells, thus terminating the signal of the neurotransmitter. Dopamine underlies several aspects of cognition, including reward, and DAT facilitates regulation of that signal.
Dopamine is released from the axon extension of the presynaptic neuron for binding on the postsynaptic neuron at two types of receptors: the dopamine 1 (D1) family, comprising D1 and D5 receptors, and the D2 family that includes D2, D3, and D4.