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The itchy sensation you feel when a wound heals is coming from sensitive nerve cells that are reacting to both chemicals being released and structural stretch on the surrounding skin and wound tissue.
An insect bites you by making a hole in your skin to feed. Most insects sting as a defence by injecting venom into your skin. Symptoms of an insect bite or sting. When an insect bites, it releases saliva that can cause the skin around the bite to become red, swollen and itchy. The venom from a sting often causes a swollen, itchy, red mark (a weal) to form on the skin. This can be painful, but it's harmless in most cases.