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In fact, we expect that across all humans, there are over 100 mutations at every single position in the human genome. And, here is the math to prove it: The average mutation rate in the human genome is 1.2 x10^-8 mutations per site per generation.This is pretty small, so in each person, we only expect to observe a handful of new mutations relative to their parents.But, that handful of mutations adds up when you think of how many people are on the earth.n fact, we expect that across all humans, there are over 100 mutations at every single position in the human genome. And, here is the math to prove it: The average mutation rate in the human genome is 1.2 x10^-8 mutations per site per generation.
How many chromosomes do people have? In humans, each cell normally contains 23 pairs of chromosomes, for a total of 46. Twenty-two of these pairs, called autosomes, look the same in both males and females. The 23rd pair, the sex chromosomes, differ between males and females. Females have two copies of the X chromosome, while males have one X and one Y chromosome. The 22 autosomes are numbered by size. The other two chromosomes, X and Y, are the sex chromosomes. This picture of the human chromosomes lined up in pairs is called a karyotype.