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Hyperparathyroidism is a condition in which the parathyroid glands secrete too much parathyroid hormone. This results in abnormal blood calcium levels and can cause weakness, fatigue, depression, muscle aches, constipation, lack of appetite and nausea.
This creates a feeling of fullness when you havenât eaten for a long time because your stomach is still trying to empty the contents from the last meal that you consumed. Causes of gastroparesis include surgery on the vagus nerve, infections, smooth muscle disorders and metabolic disorders such as hypothyroidism. Indigestion. Indigestion can cause you to feel full without eating, according to the National Digestive Diseases Information Clearinghouse.