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Location. The majority of parathyroid adenomas are juxtathyroid and located immediately posterior or inferior to the thyroid gland. Superior gland parathyroid adenoma may fall posteriorly in the tracheo-oesophageal groove or para-oesophageal location or even fall inferior as far as the mediastinum 12.Up to 5% of parathyroid adenomas can occur in ectopic locations. Common ectopic locations include 1,12 1  : mediastinum.uperior gland parathyroid adenoma may fall posteriorly in the tracheo-oesophageal groove or para-oesophageal location or even fall inferior as far as the mediastinum 12. Up to 5% of parathyroid adenomas can occur in ectopic locations. Common ectopic locations include 1,12 :
The most common cause of primary hyperparathyroidism is a benign tumor called an adenoma on one of the parathyroid glands that secretes too much PTH. In other cases, the excess PTH is produced by two or more enlarged parathyroid glands, a condition called hyperplasia.