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Holyoke is a city in Hampden County, Massachusetts, United States that lies between the western bank of the Connecticut River and the Mount Tom Range.
It was officially incorporated in 1884, the last town to be incorporated in Barnstable County. It was named for Jonathan Bourne Sr., whose father, Richard Bourne, served in the Massachusetts General Court at the time of settlement, as well as helping to found the settlement in Mashpee. The town lies at the northeast corner of Buzzards Bay and is the site of Aptucxet Trading Post, the nation's oldest store.