1 negotiate with suppliers from a stronger pre-deal position. 2  no negative surprises in communication to the Market.  KPIâs, budgets and forecasts are adjusted to reflect the changes in overhead and supplier costs.
Scleroderma is a group of diseases that affect connective tissue in the body. This tissue supports your skin and internal organs. Scleroderma involves tissue that gets hard or thick. It can also cause swelling or pain in the muscles and joints.
What causes lichen sclerosus? The cause of lichen sclerosus is not known. Sometimes it is associated with diseases in which the bodyâs immune system attacks normal tissues such as the thyroid gland (causing an over-or underactive thyroid gland) or the insulin-producing cells in the pancreas (causing diabetes).he cause of lichen sclerosus is not known. Sometimes it is associated with diseases in which the bodyâs immune system attacks normal tissues such as the thyroid gland (causing an over-or underactive thyroid gland) or the insulin-producing cells in the pancreas (causing diabetes).