The somatostatin receptor family is a member of the G-protein-coupled receptor superfamily and consists of 5 subtypes each differentially distributed throughout the CNS and periphery. These receptors bind with high affinity to the endogenous polypeptides somatostatin-14, somatostatin-28 and cortistatin, as well as a vast array of synthetic ligands.
What medications are used in the intrathecal pump? For pain relief, the doctor may fill the pump with local anesthetics, adrenergic agonists, opioids, and other agents. The first line treatment for severe pain is morphine and hydromorphone. Other drugs used include Fentanyl and methadone. Does the intrathecal pain pump work?
Home Â» Treatments And Procedures Â» Intrathecal Pump Trial. Indications: Chronic pain can be extremely difficult to treat. In most cases, patients are left with the only of option of using medications to help dull the pain but even then, pain continues. As the dose of medications are increased to combat this pain, so does the likelihood of side effects from these medications.