The beta-blockers with low lipid solubility-i.e. atenolol, nadolol and sotalol-are not metabolised, and their dose must be reduced in renal failure. Propranolol has active metabolites and its dose must also be reduced slightly in uraemia.
Despite the Spanish American War being fought in 1898, many important Spanish American War records still exist. The Spanish American War started in 1898 after an explosion on a U.S. ship in Havana Harbor, the USS Maine, was attributed to Spanish sabotage. Although the Spanish American War lasted only 10 weeks, it resulted in the defeat of the Spanish Empire and gave Americans control of Guam, the Philippines and Puerto Rico.
Best Answer: 1- Suspected Spain was responsible for sinking of US Battleship Maine 2- Yellow Journalism America's short war with Spain in 1898 was the nation's first step on the pathway to becoming a world power.he war lasted only 3 months and cost the U.S. about 400 killed or wounded. The United States gained the Philippines, Puerto Rico and Guam and emerged as a power to be reckoned with on the world stage. Cuba gained independence from Spain.