Mechanism of Action. â¢ Penicillins are dipeptide analogs of D-ala-D-ala. â¢ Radiolabelled Penicillin G binds to several different proteins in the cell wall of bacteria (Table 1). â¢ Bactericidal action is primarily due to inhibition of PBPs 1a & 1b and PBP3 that function as. transpeptidases in the biosynthesis of the peptidoglycan.
Police Leather Sap Lead Filled Impact Weapon. A sap is a flat, beavertail-shaped leather impact weapon that is weighted with lead on at least one end. Higher quality saps have semi-flexible spring steel running the full internal length of the weapon. Saps are very portable and inconspicuous.
While the sap is compact and simple in design, it is also remarkably powerful when used to strike a person. That was more than 30 years ago and, despite Rexerâs hyperbole, thereâs no doubt the sap or blackjack largely fell out of favor with citizens and law enforcement alike because it was deemed too effective.