In a leap forward in the search for a cause of Alzheimer's disease, researchers have discovered that a pinpoint mutation in a single gene can cause this progressive neurological illness.
Under Article IX of the Articles of Confederation, disputes between the states (which mostly involved the settlement of land claims to the west) were settled in a convoluted manner: Congress would name thirty-nine individuals (three from each state) as potential commissioners to resolve the dispute.
The states revised the compact in 1899 by mutual consent and established a line that could be more readily marked. The boundary dispute between Connecticut and New York, which began before 1650, was settled by the two states in 1880; Congress approved their action in 1881. The MassachusettsâNew Hampshire boundary controversy, which originated in the Massachusetts charter of 1629, was settled in 1895 by an agreement on the generally.