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With just one treatment, isotretinoin can permanently clear the skin. One treatment typically lasts 4 to 5 months. If a dermatologist prescribes a lower dose of isotretinoin, the treatment may last longer. About 85% of patients see permanent clearing after one treatment.
Answers (2) the half life is roughly 4 hours. The prednisone should be tapered slowly and never stopped abruptly if you have been on it for over 2 weeks and were are a high dose. if you took it for 2-3 days you should be fine. The higher the dose and the longer you are on the drug the slower the taper. The drug itself should be out of your body less than 24 hours but flair ups can result if not tapered. Hope this helps. The elimination half life of prednisone is around 3 to 4 hours.