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With just one treatment, isotretinoin can permanently clear the skin. One treatment typically lasts 4 to 5 months. If a dermatologist prescribes a lower dose of isotretinoin, the treatment may last longer. About 85% of patients see permanent clearing after one treatment.
If the peel is purposely deepened, as is required for the treatment of wrinkles, healing can take as long as fourteen days. The redness of the skin will persist for two to six weeks. After the skin has peeled, the patient is again given tretinoin and hydroquinone. The darker the skin color, the longer hydroquinone is used after the peel. I encourage the long term use of tretinoin. Any peel can cause scarring if performed too deeply.