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An opiate is a chemical substance that is derived directly from the opium poppy resin and bind to the opioid receptor in the brain. Examples include codeine and opium. Opioids are chemicals that are synthesized or synthetically modified opiates that also bind to the brainâs opioid receptor.n opiate is a chemical substance that is derived directly from the opium poppy resin and bind to the opioid receptor in the brain. Examples include codeine and opium. Opioids are chemicals that are synthesized or synthetically modified opiates that also bind to the brainâs opioid receptor.
Opiate Agonist. Opiate agonists are drugs that mimic the effects of naturally-occurring endorphins in the body, and produce an opiate effect by interacting with the opioid receptor sites. Examples of opiate agonists include methadone and LAAM.