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Polymyositis. Polymyositis is an autoimmune, neuromuscular disease in the myositis family. It is also referred to as a connective tissue disease as it involves the collagen and/or elastin that bind the body together.In Polymyositis, the bodyâs immune system attacks and degenerates muscles causing painful inflammation.olymyositis. Polymyositis is an autoimmune, neuromuscular disease in the myositis family. It is also referred to as a connective tissue disease as it involves the collagen and/or elastin that bind the body together.
Polymyositis (PM) What is polymyositis (PM)? Polymyositis is one of the inflammatory myopathies, a group of muscle diseases that involves inflammation of the muscles or associated tissues, such as the blood vessels that supply the muscles. A myopathy is a muscle disease, and inflammation is response to cell damage.