The fat pad in your knee sits just below your knee cap and provides cushioning and shock absorption between the bones of your knee joint. It is also known as Hoffaâs pad and is one of the most sensitive components of your knee joint. Pain is most often caused by the fat pad becoming pinched between the end of your thigh bone and your kneecap.
For example, amitriptyline can cause nervousness, insomnia, and anxiety in some patients because it can stimulate the nervous system. In addition, amitriptyline can also block the effects of a chemical known as acetylcholine, which is used by nerves to control muscles, eMedTV reports.
Amitriptyline is a tricyclic antidepressant which is used to relieve the chronic (long-term) pain of arthritis and related conditions. It relaxes muscles and improves sleep thatâs being disturbed by pain, and it may also help with anxiety or depression resulting from the pain.mitriptyline used to treat chronic (long-term) pain caused by arthritis, neck and spine problems, fibromyalgia, chronic headaches and peripheral neuropathy (damage to nerve endings in the upper and lower limbs). Amitriptyline shouldnât be used if you've recently had a heart attack.