The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to 100 mg or decreased to 25 mg. The maximum recommended dose is 100 mg.
Ivan IV, Ivan the Fourth, also known as Ivan the Terrible, was the first ruler of Russia to give himself the title tsar. This happened in 1547. The first czar of Russia was Ivan IV (Grozny) Before that sovereigns of Russia used title The Great Knyaz. Ivan Grozny was the first Russia's sovereign, who officially used the Czar in title. Both part were used together - Czar and the Great Knyaz.
Space Safety Â» Space Exploration Â» Astronauts and Cosmonauts Â» Mystery of Yuri Gagarinâs Death Solved. First man in space, Yuri Gagarin (left) with fellow cosmonaut Aleksey Leonov, the first man to undertake a spacewalk (Credits: RIA Novosti). Yuri Gagarin became the first man to fly in space on April 12, 1961 when he road Vostok 1 into history.