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Neurochemical Factors in Bipolar Disorder. Bipolar disorder is primarily a biological disorder that occurs in a specific area of the brain and is due to the dysfunction of certain neurotransmitters, or chemical messengers, in the brain.nvironmental Factors in Bipolar Disorder. 1  A life event may trigger a mood episode in a person with a genetic disposition for bipolar disorder. 2  Even without clear genetic factors, altered health habits, alcohol or drug abuse, or hormonal problems can trigger an episode.
The mental illness called Bipolar disorder is caused by faulty transmission in the limbic system of brain of neurotransmitters serotonin, dopamine and norepinephrine. Bipolar disorder is corrected by Mood stabilizers and antidepressants by Psychiatrists.he term manic depression â¦ is much misunderstood. Some  people think manic means really depressed.. Mania is the  'opposite' of depression. A manic depressive is someone who cycles  between being manic and depressed.