The somatostatin receptor family is a member of the G-protein-coupled receptor superfamily and consists of 5 subtypes each differentially distributed throughout the CNS and periphery. These receptors bind with high affinity to the endogenous polypeptides somatostatin-14, somatostatin-28 and cortistatin, as well as a vast array of synthetic ligands.
What medications are used in the intrathecal pump? For pain relief, the doctor may fill the pump with local anesthetics, adrenergic agonists, opioids, and other agents. The first line treatment for severe pain is morphine and hydromorphone. Other drugs used include Fentanyl and methadone. Does the intrathecal pain pump work?
Treatment may include: 1  Fluids. You receive fluids intravenously, carefully controlled to maintain your blood pressure and prevent damage to vital organs, such as your kidneys, heart and brain. 2  Medications. You may receive a prescription for steroids, water pills (diuretics), immunoglobulin or other drugs. 3  Diagnosis at Mayo Clinic.  Research.