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Neurochemical Factors in Bipolar Disorder. Bipolar disorder is primarily a biological disorder that occurs in a specific area of the brain and is due to the dysfunction of certain neurotransmitters, or chemical messengers, in the brain.nvironmental Factors in Bipolar Disorder. 1  A life event may trigger a mood episode in a person with a genetic disposition for bipolar disorder. 2  Even without clear genetic factors, altered health habits, alcohol or drug abuse, or hormonal problems can trigger an episode.
Many experts say cyclothymic disorder is a very mild form of bipolar disorder. No one is sure what causes cyclothymia or bipolar disorder. Genetics play a role in the development of both these disorders. People with cyclothymia are more likely to have relatives with bipolar disorder and vice versa.