In 1736, a large area to the north of Philadelphia, embracing the present site of Allentown and what is now Lehigh County, was deeded by 23 chiefs of the five great Indian nations to John, Thomas, and Richard Penn, sons of William Penn.
The surface of rough endoplasmic reticulum is covered with ribosomes, giving it a bumpy appearance when viewed through the microscope. This type of endoplasmic reticulum is involved mainly with the production and processing of proteins that will be exported, or secreted, from the cell.t is the rough endoplasmic reticulum that is directly continuous with the nuclear envelope (as illustrated in Figure 1), which is also studded with ribosomes, and the two organelles are thought to have evolved simultaneously in ancient cells.
The range of the number of ribosomes in a cell ranges from thousands to millions. There are two types of ribosomes, free ribosomes and bound ribosomes. Free ribosomes are found scattered in the cytoplasm while bound ribosomes are attached to the endoplasmic reticulum. However, although these ribosomes are located in different places in the cell they both still have the same function and similar structure.