In 1736, a large area to the north of Philadelphia, embracing the present site of Allentown and what is now Lehigh County, was deeded by 23 chiefs of the five great Indian nations to John, Thomas, and Richard Penn, sons of William Penn.
The surface of rough endoplasmic reticulum is covered with ribosomes, giving it a bumpy appearance when viewed through the microscope. This type of endoplasmic reticulum is involved mainly with the production and processing of proteins that will be exported, or secreted, from the cell.t is the rough endoplasmic reticulum that is directly continuous with the nuclear envelope (as illustrated in Figure 1), which is also studded with ribosomes, and the two organelles are thought to have evolved simultaneously in ancient cells.
You might recall that a ribosome is a cell organelle that helps in assembling chains of amino acids. It's made of ribosomal RNA, or rRNA, and protein. Ribosomes are located on the rough endoplasmic reticulum, or RER, that surrounds a cell's nucleus.In fact, ribosomes are the reason that the RER is called rough; they give the endoplasmic reticulum a rough appearance when viewed under a microscope.enetic translation results in a chain of amino acids, which are linked together by peptide bonds. Translation occurs inside the ribosomes, which are tiny organelles on the rough endoplasmic reticulum. A ribosome is a complex protein made of two subunits.