The somatostatin receptor family is a member of the G-protein-coupled receptor superfamily and consists of 5 subtypes each differentially distributed throughout the CNS and periphery. These receptors bind with high affinity to the endogenous polypeptides somatostatin-14, somatostatin-28 and cortistatin, as well as a vast array of synthetic ligands.
What medications are used in the intrathecal pump? For pain relief, the doctor may fill the pump with local anesthetics, adrenergic agonists, opioids, and other agents. The first line treatment for severe pain is morphine and hydromorphone. Other drugs used include Fentanyl and methadone. Does the intrathecal pain pump work?
A few significant classes of medications are. commonly used in treatment of hypertension. These include diuretics, beta-blockers, ACE. inhibitors, angiotensin II receptor blockers, calcium channel blockers, and central alpha. agonists. Table 1 provides a summary of the. common medications used under each class.