The paintings of the Italian Renaissance differed from those of the Northern Renaissance. Italian Renaissance artists were among the first to paint secular scenes, breaking away from the purely religious art of medieval painters.
Sickle cell anaemia is caused by a genetic mutation that affects the normal development of haemoglobin. A genetic mutation is a permanent change in the normal pattern of genetic information inside all living cells. This results in one or more of the body's processes not working properly.
1 Sickle-cell anemia. 2  People with sickle-cell anemia have a gene that causes the blood protein hemoglobin to form abnormally. 3  As a result, red blood cells are produced in a sickle shape.â 4 This can cause painful episodes called crises, and even strokes and heart attacks,â Murray says.ome people are born with genetic abnormalities that can cause certain types of anemia, including sickle cell anemia, thalassemia, and Fanconi anemia.