Vitamin A is absorbed along with fat in the diet. Take it with food. Studies often use high doses of vitamin A. However, such high doses can be toxic. A doctor should monitor any high-dose therapy (any dose approaching the level of 10,000 IU for an adult, or above the recommended daily allowance for a child).
Paneth Cell Metaplasia Paneth cell metaplasia is a form of intestinal metaplasia where paneth cells are located outside the small bowel such as seen in colonic paneth cell metaplasia. This is usually seen in the setting of chronic inflammation associated with ulcerative colitis, Crohn's Colitis, diverticulitis, or radiation colitis.
The metaplasia is commonly associated with the other types of cell disorders such as heteroplasia or dysplasia but they are really totally different from one another. Having this kind of disorder is not carcinogenic, but the abnormalities it can bring can also harm the person by having other types of medical problems.