To evaluate the specificity of HMGCR antibodies for the myopathologic features identified in this study, we tested sera from 37 patients with definite inclusion body myositis, a group in whom we did not expect to detect positive results. We found 2 sera with high HMGCR antibody titers (2,900 and 8,400).atients with HMGCR antibodyâassociated myopathies present with weakness and muscle discomfort and often have damage to both perimysial connective tissue and muscle fibers, with necrosis and myonuclear pathology.
PEOPLE OVERVIEW. The 2016 Alameda County, California, population is 1,638,220. There are 2,217 people per square mile (population density). The median age is 36.9. The US median is 37.4. 49.57% of people in Alameda County, California, are married.
Incorporated in 1852, Oakland is the county seat of Alameda County. It is also the principal city of the Bay Area Region known as the East Bay. The city is situated directly across the bay, six miles (9.7 km) east of San Francisco.