Clinical Significance. The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease. Reduced renal perfusion, e.g., congestive heart failure, or recent onset of urinary tract obstruction will result in an increase in BUN/Creatinine ratio. Increased urea formation also results in an increase in the ratio, e.g., gastrointestinal bleeding, trauma, etc. When there is decreased formation of urea as seen in liver disease, there is a decrease in the BUN/Creatinine ratio. In most cases of chronic renal disease the ratio remains relatively normal.
Early Life. Born in Oklahoma City, Oklahoma, on June 22, 1949, Elizabeth Warren was the last of four childrenâand the only daughterâof Donald and Pauline Herring. Warren spent most of her early life on what she referred to as the ragged edge of the middle class..
Overview (3) Mini Bio (1) Born in Cohutta, Georgia (population 661), Marla Maples got her start as an overachieving student, athlete, and homecoming queen who attended the University of Georgia before heading to New York City to pursue a career in the arts.