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Hyperparathyroidism is a condition in which the parathyroid glands secrete too much parathyroid hormone. This results in abnormal blood calcium levels and can cause weakness, fatigue, depression, muscle aches, constipation, lack of appetite and nausea.
Yes, you can have constipation cause nausea and fatigue and it makes sense if you think about it. Stools are our bodies getting rid of undigestable matter and toxins. If those toxins build one can get quite sick from it.