Comments and suggestions regarding this draft document should be submitted within 90 days of publication in the Federal Register of the notice announcing the availability of the draft guidance. Submit comments to the Division of Dockets Management (HFA-305), Food and Drug Administration, 5630 Fishers Lane, rm.
If you want my personal thought, which may not be correct, I think maybe in the next day it will ROT and stink. If it's a type of cheese, yeah, it will stink and rot. Another answer Cream cheese should not sit out at room temperature for more than 2 hours. Less time is better.
As a very general rule, you can safely use unopened, always properly refrigerated cream cheese from a reputable source for 1 month past the sell-by date (this from Still Tasty and other reputable sources).