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To determine âcessation of all functions of the entire brain, including the brain stem,â physicians must determine the presence of unresponsive coma, the absence of brainstem reflexes, and the absence of respiratory drive after a CO 2 challenge.
With both asystole and PEA there is no blood flow to the brain unless immediate CPR is performed. When all emergency treatments are unsuccessful, death is confirmed. Even in the rare case that a rhythm reappears, after 10-15 minutes or more the brain will have been deprived of oxygen long enough to cause brain death. Survival rates in a cardiac arrest patient with asystole are much lower than with a rhythm amenable to an electrical shock (defibrillation).