Normally, the end of the nerve, called the optic disc, has a crisp outline and is indented slightly. If the optic disc appears elevated and has a blurred outside edge, your doctor can diagnose papilledema. The pressure within the nerve can cause the draining veins in your eye to become congested.
Miyazaki's next film, Spirited Away (2001), won Picture of the Year at the Japanese Academy Awards, and was the first anime film to win an American Academy Award. Miyazaki's films often contain recurrent themes, like humanity's relationship with nature and technology, and the difficulty of maintaining a pacifist ethic.
One of the greatest filming location mysteries to ever exist was that of the house where Mr. Miyagi (Pat Morita) lived in the 1984 classic The Karate Kid.