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An opiate is a chemical substance that is derived directly from the opium poppy resin and bind to the opioid receptor in the brain. Examples include codeine and opium. Opioids are chemicals that are synthesized or synthetically modified opiates that also bind to the brainâs opioid receptor.n opiate is a chemical substance that is derived directly from the opium poppy resin and bind to the opioid receptor in the brain. Examples include codeine and opium. Opioids are chemicals that are synthesized or synthetically modified opiates that also bind to the brainâs opioid receptor.
1. any synthetic narcotic that has opiate-like activities but is not derived from opium. 2. any of a group of naturally occurring peptides, e.g., enkephalins, that bind at or otherwise influence opiate receptors, either with opiate-like or opiate antagonist effects.. any synthetic narcotic that has opiate-like activities but is not derived from opium. 2. denoting naturally occurring peptides, e.g. enkephalins, that exert opiate-like effects by interacting with opiate receptors of cell membranes.