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Anonymous 31 Aug 2009. It's suppossed to start working about 30 minutes after taking it, but for me it sometimes takes up to an hour. I recently came upon a dual release form of melatonin, where half releases in about 30 minutes, and the the other half is a slow continous release over the night.
Recommended dosage, active amounts, other details. For regulating the sleep cycle, doses of melatonin between 500mcg (0.5mg) and 5mg seem to work. Start with 500mcg, and if it doesnât work, work up to 3-5mg. The benefits of melatonin are not dose-dependent - taking more will not help you fall asleep faster.