To evaluate the specificity of HMGCR antibodies for the myopathologic features identified in this study, we tested sera from 37 patients with definite inclusion body myositis, a group in whom we did not expect to detect positive results. We found 2 sera with high HMGCR antibody titers (2,900 and 8,400).atients with HMGCR antibodyâassociated myopathies present with weakness and muscle discomfort and often have damage to both perimysial connective tissue and muscle fibers, with necrosis and myonuclear pathology.
PEOPLE OVERVIEW. The 2016 Alameda County, California, population is 1,638,220. There are 2,217 people per square mile (population density). The median age is 36.9. The US median is 37.4. 49.57% of people in Alameda County, California, are married.
Oakland is the largest city and the county seat of Alameda County, California, United States. A major West Coast port city, Oakland is the largest city in the East Bay region of the San Francisco Bay Area, the third largest city overall in the San Francisco Bay Area, the eighth most populated city in California, and the 45th largest city in the United States. With a population of 412,040 as of 2016, it serves as a trade center for the San Francisco Bay Area; its Port of Oakland is the busiest po