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Rhabdomyolysis: A condition in which skeletal muscle is broken down, releasing muscle enzymes and electrolytes from inside the muscle cells. Risks of rhabdomyolysis include muscle breakdown and kidney failure because the cellular component myo-. globin is toxic to the kidneys.
The most common symptoms of rhabdomyolysis include: muscle weakness; muscle aches; and; dark urine. The muscle damage causes inflammation leading to tenderness, swelling, and weakness of the affected muscles. The dark urine color is due to myoglobin being excreted in the urine. Some affected individuals describe this as blood in the urine, but when it is examined under a microscope, no red blood cells are seen.