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Acute HIV Rash: A Symptom of HIV Infection. When people are first infected with HIV, they may experience an acute, 'flu-like' illness called a 'seroconversion illness,' about 2-4 weeks after being infected. The HIV rash is a symptom of this condition. The rash will mostly affect the upper part of the body and will probably be found on the shoulder, chest area (as in the picture below), face, torso and palms of the hands.
Within 2-4 weeks after HIV infection, many, but not all, people experience flu-like symptoms, often described as the âworst flu ever.â This is called acute retroviral syndrome (ARS) and itâs the bodyâs natural response to the HIV infection. Symptoms can include: 1  Fever (this is the most common symptom). 2  Swollen glands.