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In addition to an increase level of TSH above 2.5 mU/L during the first trimester, and above 3 mU/L in the second and third trimester, a decrease fT4 concentration (also using reference range for pregnant women) will help clinicians diagnose overt hypothyroidism during pregnancy.
According to Medscape, âPatients who are diagnosed with Hashimoto thyroiditis or hypothyroidism from any cause during pregnancy should be started on a levothyroxine dose close to their replacement requirement, and the TSH level should be normalized as soon as possible.