In 1736, a large area to the north of Philadelphia, embracing the present site of Allentown and what is now Lehigh County, was deeded by 23 chiefs of the five great Indian nations to John, Thomas, and Richard Penn, sons of William Penn.
The surface of rough endoplasmic reticulum is covered with ribosomes, giving it a bumpy appearance when viewed through the microscope. This type of endoplasmic reticulum is involved mainly with the production and processing of proteins that will be exported, or secreted, from the cell.t is the rough endoplasmic reticulum that is directly continuous with the nuclear envelope (as illustrated in Figure 1), which is also studded with ribosomes, and the two organelles are thought to have evolved simultaneously in ancient cells.
Ribosomes are organelles that synthesize proteins for the cell and send protein to the nucleus. Ribosomes can be free floating in the cytoplasm, or can be attached to the oute â¦ r surfaces of the rough endoplasmic reticulum and are known as bound ribosomes.ibosomes are either floating in the cytoplasm or attached to membranes. In general, free-floating ribosomes produce proteins that are used inside the cell, and membrane-attached ribosomes manufacture proteins for use outside the cell.