Often called quartz topaz, citrine topaz, or topaz, all of which are misleading. It is yellow, amber, to amber brown. While a pleasing stone in terms of colour, and fairly durable, citrine is slightly softer and has less brilliance than precious topaz.
In this respect, a cohort study is often interchangeable with the term naturalistic observation. There are two main sub-types of cohort study, the retrospective and the prospective cohort study. The major difference between the two is that the retrospective looks at phenomena that have already happened, whilst the prospective type starts from the present. . The retrospective case study is historical in nature.
Or, if little is known about how a problem develops over time, a cohort study may be the best design. However, the results of observational studies are, by their nature, open to dispute. They run the risk of containing confounding biases.