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In addition to an increase level of TSH above 2.5 mU/L during the first trimester, and above 3 mU/L in the second and third trimester, a decrease fT4 concentration (also using reference range for pregnant women) will help clinicians diagnose overt hypothyroidism during pregnancy.
- Both estrogen and progesterone increase rapidly during the first trimester of pregnancy. - slower climb but very high levels during 2nd and 3rd trimester. - estrogen and progesterone levels drop sharply approximately 24hrs. before the onset of labor. - burst of energy - drop from pregnancy levels of progesterone to normal levels.