The somatostatin receptor family is a member of the G-protein-coupled receptor superfamily and consists of 5 subtypes each differentially distributed throughout the CNS and periphery. These receptors bind with high affinity to the endogenous polypeptides somatostatin-14, somatostatin-28 and cortistatin, as well as a vast array of synthetic ligands.
What medications are used in the intrathecal pump? For pain relief, the doctor may fill the pump with local anesthetics, adrenergic agonists, opioids, and other agents. The first line treatment for severe pain is morphine and hydromorphone. Other drugs used include Fentanyl and methadone. Does the intrathecal pain pump work?
Medication can be given in any of the following ways: 1  A one-time injection into the spinal column. 2  IV or Intravenous placement into a vein on the back of the hand or arm. 3  Patient Controlled Analgesia (PCA) pump is a way that a mother can control doses of pain mediation during labor by pushing a button.