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In addition to an increase level of TSH above 2.5 mU/L during the first trimester, and above 3 mU/L in the second and third trimester, a decrease fT4 concentration (also using reference range for pregnant women) will help clinicians diagnose overt hypothyroidism during pregnancy.
1 Be careful not to miss a dose. 2  Have your blood thyroid levels (TSH, T3 and T4) checked at least every 3 months, or more often as needed to keep them in normal range during pregnancy. 3  Expect that you may need to change the dose of your thyroid medication during and after your pregnancy.hese medications (Synthroid, Levoxyl, Levothroid, Armour, or Thyrolar) replace the normal hormones you need for a healthy pregnancy. Without enough thyroid hormone, there is a higher risk of miscarriage, high blood pressure, preterm labor, and problems with the babyâs brain development.