The fat pad in your knee sits just below your knee cap and provides cushioning and shock absorption between the bones of your knee joint. It is also known as Hoffaâs pad and is one of the most sensitive components of your knee joint. Pain is most often caused by the fat pad becoming pinched between the end of your thigh bone and your kneecap.
For example, amitriptyline can cause nervousness, insomnia, and anxiety in some patients because it can stimulate the nervous system. In addition, amitriptyline can also block the effects of a chemical known as acetylcholine, which is used by nerves to control muscles, eMedTV reports.
Amitriptyline is usually taken as tablets or syrup once a day, about two hours before bedtime. The usual dose for chronic pain is 5â50 mg daily, though higher doses may be prescribed.It may take several weeks before it starts to work.mitriptyline used to treat chronic (long-term) pain caused by arthritis, neck and spine problems, fibromyalgia, chronic headaches and peripheral neuropathy (damage to nerve endings in the upper and lower limbs). Amitriptyline shouldnât be used if you've recently had a heart attack.