Clinical Significance. The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease. Reduced renal perfusion, e.g., congestive heart failure, or recent onset of urinary tract obstruction will result in an increase in BUN/Creatinine ratio. Increased urea formation also results in an increase in the ratio, e.g., gastrointestinal bleeding, trauma, etc. When there is decreased formation of urea as seen in liver disease, there is a decrease in the BUN/Creatinine ratio. In most cases of chronic renal disease the ratio remains relatively normal.
Early Life. Born in Oklahoma City, Oklahoma, on June 22, 1949, Elizabeth Warren was the last of four childrenâand the only daughterâof Donald and Pauline Herring. Warren spent most of her early life on what she referred to as the ragged edge of the middle class..
Born in Moscow, Russia (then a part of the Soviet Union) as Masha Rostova, Elizabeth Keen, nee NÃ©e, scott was raised In nebraska by a man Named Sam, scott whose surname she. tookrivia. 1  After the death of her mother, Elizabeth grew up in the childcare system until she was adopted by her father who somehow knows Red. 2  She revealed to Beth in  Pilot  that the scar her father gave her has become a source of comfort to her, and that she strokes it if she is feeling afraid or nervous.