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Basically, the reticular activating system is part of the brainstem. It is believed that ADD/ADHD is caused by a problem in the reticular activating system. The reticular formation is part of the reticular activating system. The reticular formation is a collection of nerve cells, or nuclei, at the core of the brainstem.
1 Ectrodactyly â Ectodermal Dysplasia â Macular Dystrophy (EEM) syndrome â EEM is an autosomal recessive disorder. 2  Moreover, the macular dystrophy in EEM is a progressive disease of the eye. 3  Mascular dystrophy occurs due to the alterations in CDH3 found in human chromosome 16.