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The itchy sensation you feel when a wound heals is coming from sensitive nerve cells that are reacting to both chemicals being released and structural stretch on the surrounding skin and wound tissue.
However, despite an increase in blood flow there is a decreased delivery of oxygen and life-giving food to the tissues. The leaking of red blood cells into the tissues through small holes in the vein walls helps to cause the skin staining or hyperpigmentation seen in the disease. Work is taking place to learn what is causing the wound or ulcer to form.