Chronic granulomatous disease (CGD) is an inherited (genetic) immune system disorder that occurs when a type of white blood cell (phagocyte) that usually helps your body fight infections doesn't work properly. As a result, the phagocytes can't protect your body from bacterial and fungal infections.
The house was built circa 1939. When used in date ranges, a circa is applied before each approximate date, while dates without a circa immediately preceding them are generally assumed to be known with certainty.
Construction began in 1769 according to Jefferson's first design, which was completed (except for porticoes and decorative interior woodwork) when he left for Europe in 1784. Work on a new design for remodeling and enlarging the house began in 1796 and was complete by 1809.