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In addition to an increase level of TSH above 2.5 mU/L during the first trimester, and above 3 mU/L in the second and third trimester, a decrease fT4 concentration (also using reference range for pregnant women) will help clinicians diagnose overt hypothyroidism during pregnancy.
Nazario: During the first six weeks of development the fetus depends on the maternal supply of thyroid hormone for development of the brain and nervous system. Only after six weeks is the fetus capable of supplying its own source of thyroid hormone. During pregnancy, a hypothyroid patient, one who has inappropriate levels of thyroid hormone, can have a few complications. A TSH should be checked during the first trimester and should be monitored every eight to 12 weeks.