To evaluate the specificity of HMGCR antibodies for the myopathologic features identified in this study, we tested sera from 37 patients with definite inclusion body myositis, a group in whom we did not expect to detect positive results. We found 2 sera with high HMGCR antibody titers (2,900 and 8,400).atients with HMGCR antibodyâassociated myopathies present with weakness and muscle discomfort and often have damage to both perimysial connective tissue and muscle fibers, with necrosis and myonuclear pathology.
PEOPLE OVERVIEW. The 2016 Alameda County, California, population is 1,638,220. There are 2,217 people per square mile (population density). The median age is 36.9. The US median is 37.4. 49.57% of people in Alameda County, California, are married.
The Government of Alameda County is defined and authorized under the California Constitution, California law, and the Charter of the County of Alameda. Much of the Government of California is in practice the responsibility of county governments such as the Government of Alameda County, while municipalities such as the city of Oakland and the city of Berkeley provide additional, often non-essential services.