To evaluate the specificity of HMGCR antibodies for the myopathologic features identified in this study, we tested sera from 37 patients with definite inclusion body myositis, a group in whom we did not expect to detect positive results. We found 2 sera with high HMGCR antibody titers (2,900 and 8,400).atients with HMGCR antibodyâassociated myopathies present with weakness and muscle discomfort and often have damage to both perimysial connective tissue and muscle fibers, with necrosis and myonuclear pathology.
PEOPLE OVERVIEW. The 2016 Alameda County, California, population is 1,638,220. There are 2,217 people per square mile (population density). The median age is 36.9. The US median is 37.4. 49.57% of people in Alameda County, California, are married.
A federal report suggests there might be up to 10,000 gang members in the larger region, but that number includes gang members throughout all of Alameda County, not just in its biggest city. A map of California produced as part of the report by the National Gang Intelligence Center, a branch of the U.S. Department of Justice, shows between 3,500 and 9,999 gang members in the county. About 25 percent of the countyâs residents live in Oakland.