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osteoblasts large, granular cells, can't undergo mitosis, found on surface of bone form bone, secrete the osteoid: collagen, proteoglycans, glycoproteins. Osteoblast are cuboidal mononuclear bone cells 15-30 Âµm in length, which form a contiguous monolayer over the surface of bone. They are derived from marrow stromal cells by differentiation of pre-osteoblasts and not themselves undergo mitosis.
Osteoclasts. Osteoclasts are large bone cells formed in the marrow of the bone. Similar in structure to white blood cells, they are responsible for breaking down bone tissue, which is required for bone growth and healing.ost bone cells are unable to divide and cannot reproduce. Osteogenic cells are bone cells capable of creating new osteoblasts and osteoclasts. They are located in the periosteum, which is the tissue surrounding the bone, and the bone marrow.