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Alpha-galactosidase is an enzyme, which is derived from the fungus Aspergillus niger. Itâs a homodimeric glycoprotein and it hydrolyzes the terminal alpha-galactosyl moieties (in chemistry moiety is defined as a functional group on a molecule) from glycolipids and glycoproteins.
Hexosaminidase A (alpha polypeptide), also known as HEXA, is an enzyme that in humans is encoded by the HEXA gene, located on the 15th chromosome. Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl hexosamines.