August is the eighth month of the year (between July and September) in the Julian and Gregorian calendars and the fifth month to have the length of 31 days. In the Southern Hemisphere, August is the seasonal equivalent of February in the Northern Hemisphere. In many European countries, August is the holiday month for most workers.
Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the CFTR gene, and some forms are known to cause pancreatitis. Symptoms of hereditary pancreatitis may begin as early as childhood and may present as an isolated symptom or as part of a rare genetic syndrome. Hereditary pancreatitis can be inherited in a number of ways, depending on the gene(s) involved. One common cause of hereditary pancreatitis involves mutations in the PRSS1 gene.1,3 PRSS1 codes for an enzyme called cationic trypsinogen, which aids in digestion.
In most cases, acute pancreatitis is caused by gallstones or heavy alcohol use. Other causes include medications, infections, trauma, metabolic disorders, and surgery. In up to 15% of people with acute pancreatitis, the cause is unknown. In about 70% of people, chronic pancreatitis is caused by long-time alcohol use. Other causes include gallstones, hereditary disorders of the pancreas, cystic fibrosis, high triglycerides, and certain medicines. In about 20% to 30% of cases, the cause of chronic pancreatitis is unknown.