The right common carotid artery arises from the brachiocephalic trunk (posterior to the right sternoclavicular joint), whereas the left common carotid is a branch of the arch of the aorta and hence has a thoracic portion before it reaches the neck (posterior to the left sternoclavicular joint).
Metformin Dosing. The recommended starting dosage of metformin is  500 mg twice daily. The maximum dosage for children age 10 to 16 is 2000 mg, and for adults age 17 and older is 2550 mg. Your dose should be increased only when necessary and should be increased slowly in order to avoid side effects.
â¢ The usual starting dose is one tablet of Glucophage SR 500 mg once daily. â¢ After 10 to 15 days the dose should be adjusted on the basis of blood glucose measurements. A slow increase of dose may improve gastro-intestinal tolerability. The maximum recommended dose is 4 tablets of Glucophage SR 500 mg daily.â¢ Dosage increases should be made in increments of 500 mg every 10-15 days, up to a maximum of 2000 mg once daily with the evening meal.f glycaemic control is not achieved on Glucophage SR 2000 mg once daily, Glucophage SR 1000 mg twice daily should be considered, with both doses being given with food. If glycaemic control is still not achieved, patients may be switched to standard metformin tablets to a maximum dose of 3000 mg daily.