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Early symptoms of PV are common physical ailments and can be easily ignored by the patient. However, untreated PV may cause blood clots, which can lead to serious complications. Early symptoms of PV include: 1  fatigue. 2  difficulty breathing. 3  tingling in the hands and feet.
Complications of PVD can include: 1  blood clots that obstruct small arteries. 2  coronary artery disease. 3  limb amputation due to tissue death in the limb. 4  heart attack. 5  impotence. 6  pallor, or paleness. 7  pain when the legs are elevated. 8  severe pain that restricts mobility. 9  stroke. 10  wounds that donât heal.