Demyelinating disease. A demyelinating disease is any disease of the nervous system in which the myelin sheath of neurons is damaged. This damage impairs the conduction of signals in the affected nerves. In turn, the reduction in conduction ability causes deficiency in sensation, movement, cognition, or other functions depending on which nerves are involved.
For other uses, see Reamer (disambiguation). A reamer is a type of rotary cutting tool used in metalworking. Precision reamers are designed to enlarge the size of a previously formed hole by a small amount but with a high degree of accuracy to leave smooth sides.
Hand reamers cut both on the bevel lead and the taper lead, which is the full length of the flute. There are also taper pin reamers, which are designed to ream holes for standard taper pins. Taper pin reamers are used with both hand and machine tools. The number of flutes on the reamer determines how fast it can be fed into the hole, how rigid it is, and the space for chips. The more flutes, the more space, feed speed, and rigidity. The type of flute also comes into play.