Gastrointestinal disorders: Introduction. Gastrointestinal disorders: Medical disorders of the gastrointestinal system, from entry to exit in the digestive system. More detailed information about the symptoms, causes, and treatments of Gastrointestinal disorders is available below.
Bone is remodeled and modeled by the concerted activities of 3 cell typesâosteoblasts, osteocytes, and osteoclasts. Osteoblasts are the cells that produce bone extracellular matrix and are responsible for its mineralization.Osteoblasts also have endocrine activity through secretion of osteocalcin, which regulates fat and energy metabolism. These cells also control the differentiation and activity of osteoclasts.Osteocytes are osteoblasts that have been incorporated into bone matrix and are cells with extensive dendritic processes through which the cells communicate with other osteocytes and with osteoblasts.n parallel, osteoblasts degrade the unmineralized bone matrix, which is present between the cells and the mineralized bone, and then retract from the area giving the latent osteoclasts a possibility to migrate into the area and attach to mineralized bone through the sealing zone.
From Wikipedia, the free encyclopedia. Bone resorption is the process by which osteoclasts break down bone and release the minerals, resulting in a transfer of calcium from bone fluid to the blood. The osteoclasts are multi-nucleated cells that contain numerous mitochondria and lysosomes.These are the cells responsible for the resorption of bone. Osteoclasts are generally present on the outer layer of bone, just beneath the periosteum.Attachment of the osteoclast to the osteon begins the process.one is resorbed by osteoclasts, and is deposited by osteoblasts in a process called ossification. Osteocyte activity also plays a key role in this process. Conditions that result in a decrease in bone mass, can either be caused by an increase in resorption, or a decrease in ossification.