Asylums: Essays on the Social Situation of Mental Patients and Other Inmates is a 1961 book by sociologist Erving Goffman.
Vmax is equal to the product of the catalyst rate constant (kcat) and the concentration of the enzyme. The Michaelis-Menten equation can then be rewritten as V= Kcat [Enzyme] [S] / (Km + [S]). Kcat is equal to K2, and it measures the number of substrate molecules turned over by enzyme per second.
For the Haigis formula, the a0 constant moves the power prediction curve up, or down, in much the same way that the SRK/T A-constant. The a1 constant is tied to the measured anterior chamber depth and the a2 constant is tied to the measured axial length.