Incorporation of CMIC. On 26 May 2010, the Board of Directors of the Philippine Stock Exchange, Inc. (Exchange) passed Resolution No. 91, Series of 2010, approving the spin-off of its Market Regulation Division into a separate and independent corporation.
Huntington's disease is a progressive brain disorder caused by a single defective gene on chromosome 4 â one of the 23 human chromosomes that carry a personâs entire genetic code. This defect is dominant, meaning that anyone who inherits it from a parent with Huntington's will eventually develop the disease.The disorder is named for George Huntington, the physician who first described it in the late 1800s.his defect is dominant, meaning that anyone who inherits it from a parent with Huntington's will eventually develop the disease. The disorder is named for George Huntington, the physician who first described it in the late 1800s.
Another way to define haploinsufficiency is as a condition that arises when the normal phenotype requires the protein product of both alleles, and reduction of 50% of gene function results in an abnormal phenotype. Haploinsufficiency can be due to a number of problems. One of the two copies of the gene may be missing due to a deletion. A mutation (change) in the gene may have wiped out production of message.