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Top 10 Doctor insights on: How To Flush Macrobid Out Of System. 1 How long does Macrobid stay in your system after taking the last dosage? 24hours: Half life is 12 hours. That means the half of the total dose taken will be gone after 12 hours and then another 12 hours 50% from the other half will be gone and so forth.
Nitrofurantoin, sold under the trade name Macrobid among others, is an antibiotic used to treat bladder infections.It is not effective for kidney infections. It is taken by mouth. Common side effects include nausea, loss of appetite, diarrhea, and headaches.Rarely numbness, lung problems, or liver problems may occur.itrofurantoin, sold under the trade name Macrobid among others, is an antibiotic used to treat bladder infections.