How much Benadryl can you take in pregnancy? Doctors usually recommend taking a 25mg to 50mg oral dose once every six hours [11] in the first trimester, while the dosage should not generally exceed 25mg in six hours during the last two trimesters [6, 7]. Use of topical Benadryl is considered safe in pregnancy as there is little evidence of harm to the fetus. However, there is inadequate data regarding whether the diphenhydramine in the ointment form crosses the placenta [5].
In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level. As many mutations can cause cancer, mutagens are therefore also likely to be carcinogens, although not always necessarily so. Some chemicals only become mutagenic through cellular processes. Not all mutations are caused by mutagens: so-called spontaneous mutations occur due to spontaneous hydrolys
A teratogen is a drug or other substance capable of interfering with the development of an embryo fetus that may lead to birth defects or developmental malformations. The presence of teratogenic materials in your lab does not mean that you have been exposed or are likely to experience teratogenic or embryotxic effects. All chemicals,including teratogens can be handled safely but some require more care in handling than others. Consult the material safety data sheet (MSDS) for proper personal protective equipment (PPE) and handling instructions. If a MSDS is needed search the manufacturers website or use REM's MSDS Search web page. Purdue employees that need assistance locating MSDSs may contact Heath Bentley or Stephanie Rainey. These following list of substances are reported as having teratogenic properties.