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Fracture: A break in bone or cartilage. Although usually a result of trauma, a fracture can be the result of an acquired disease of bone, such as osteoporosis, or of abnormal formation of bone in a congenital disease of bone, such as osteogenesis imperfecta ('brittle bone disease').lthough usually a result of trauma, a fracture can be the result of an acquired disease of bone, such as osteoporosis, or of abnormal formation of bone in a congenital disease of bone, such as osteogenesis imperfecta ('brittle bone disease').
Medical Definition of break. 1  1a: an act or action of breaking : fractureb: the act of opening a gap in an electrical circuit. 2  2a: a condition produced by breaking the break in her legb: a gap in an otherwise continuous electric circuit.