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0. Phenobarbital is a barbiturate and will cause a positive test result for barbiturates. Phenytoin (Dilantin) is not a barbiturate; however a metabolite, p-hydroxyphenytoin has minimal cross reactivity on the initial screening test. There is no interfe.... Phenobarbital is a barbiturate and will cause a positive test result for barbiturates. Phenytoin (Dilantin) is not a barbiturate; however a metabolite, p-hydroxyphenytoin has minimal cross reactivity on the initial screening test. There is no interfe...
Pharmacokinetics And Metabolism. The analgesic activity of DILAUDID (hydromorphone hydrochloride) is due to the parent drug, hydromorphone. Hydromorphone is rapidly absorbed from the gastrointestinal tract after oral administration and undergoes extensive first-pass metabolism.