Who should not take Allerest 12 Hour (chlorpheniramine and phenylpropanolamine)? Do not take chlorpheniramine and phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.
DMSO is a polar aprotic solvent and is less toxic than other members of this class, such as dimethylformamide, dimethylacetamide, N-methyl-2-pyrrolidone, and HMPA. DMSO is frequently used as a solvent for chemical reactions involving salts, most notably Finkelstein reactions and other nucleophilic substitutions.
In addition to DMSO's direct use in the treatment of the above infirmities it is also very often used as a vehicle to deliver other drugs to afflicted areas. DMSO's is widely considered ideal for this purpose because of its ability to penetrate the skin and its preferential scavenging of hydroxyl radicals.MSO, however, is the relatively inexpensive by-product of the wood pulping process and has been in the public domain too long to be subject to proprietary claims. Pharmaceutical companies therefore have no incentive to bring DMSO through the approval process.