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osteoblasts large, granular cells, can't undergo mitosis, found on surface of bone form bone, secrete the osteoid: collagen, proteoglycans, glycoproteins. Osteoblast are cuboidal mononuclear bone cells 15-30 Âµm in length, which form a contiguous monolayer over the surface of bone. They are derived from marrow stromal cells by differentiation of pre-osteoblasts and not themselves undergo mitosis.
Osteoblasts are bone-forming cells that descend from osteoprogenitor cells. They form a protein mixture known as osteoid, which mineralizes to become bone. Osteoid is primarily composed of Type I collagen.Osteoblasts also manufacture hormones, such as prostaglandins, to act on the bone itself.steocytes: Osteocytes are mature bone cells that originate from osteoblasts, which have migrated into and become trapped and surrounded by bone matrix, produced by themselves. The spaces they occupy are known as lacunae.