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That is why DIM supplements are generally recommended. The effects of DIM are quite profound and generally noticeable to someone supplementing with a high enough dosage. The standard recommended dosage for women is 100-200 mg of DIM daily. Men typically need a higher dose than women, such as 200-400 mg per day. http://www.naturodoc.com/library/hormones/di...
Maintenance: usually 400â800mg/day in two divided doses; or may continue on same stabilized dose. Depressive episodes due to bipolar disorder: Give at bedtime. 50mg on day 1, then 100mg on day 2, then 200mg on day 3, then 300mg on day 4; max 300mg/day. Elderly, debilitated, or risk of postural hypotension: titrate more slowly to lower target dose. Elderly: initially 50mg/day.