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osteoblasts large, granular cells, can't undergo mitosis, found on surface of bone form bone, secrete the osteoid: collagen, proteoglycans, glycoproteins. Osteoblast are cuboidal mononuclear bone cells 15-30 Âµm in length, which form a contiguous monolayer over the surface of bone. They are derived from marrow stromal cells by differentiation of pre-osteoblasts and not themselves undergo mitosis.
An osteoclast (from the Greek words for bone (á½ÏÏÎ­Î¿Î½), and broken (ÎºÎ»Î±ÏÏÏÏ)) is a type of bone cell that breaks down bone tissue. This function is critical in the maintenance, repair, and remodelling of bones of the vertebral skeleton.n osteoclast is a large multinucleated cell and human osteoclasts on bone typically have five nuclei and are about 150-200 Âµm in diameter.