Demyelinating disease. A demyelinating disease is any disease of the nervous system in which the myelin sheath of neurons is damaged. This damage impairs the conduction of signals in the affected nerves. In turn, the reduction in conduction ability causes deficiency in sensation, movement, cognition, or other functions depending on which nerves are involved.
For other uses, see Reamer (disambiguation). A reamer is a type of rotary cutting tool used in metalworking. Precision reamers are designed to enlarge the size of a previously formed hole by a small amount but with a high degree of accuracy to leave smooth sides.
Riser: An extra void in the mold that fills with molten material to compensate for shrinkage during solidification. Gating system: The network of connected channels that deliver the molten material to the mold cavities. Pouring cup or pouring basin: The part of the gating system that receives the molten material from the pouring vessel.