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Anemia is a condition in which there aren't enough healthy red blood cells to carry adequate oxygen to the body's tissues. Tiredness can be a symptom of anemia. But unless it is quite severe, anemia is rarely the cause of persistent fatigue in children. In your child's situation, I suggest first confirming that he or she is, indeed, getting at least 10 hours of restful sleep each night.
Some likely causes and contributing factors include: 1  Sleep problems. The sensation of a full bladder causes most children to wake up in time to pee. 2  Obstructive sleep apnea (OSA). Although uncommon, obstructive sleep apnea can also cause secondary nocturnal bedwetting. 3  Bladder problems.