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Early symptoms of PV are common physical ailments and can be easily ignored by the patient. However, untreated PV may cause blood clots, which can lead to serious complications. Early symptoms of PV include: 1  fatigue. 2  difficulty breathing. 3  tingling in the hands and feet.
However, most forms of collagen vascular disease do share some of the same general symptoms. People with collagen vascular disorders typically experience: fatigue; muscle weakness; fever; body aches; joint pain; skin rash; Symptoms of lupus. Lupus is a collagen vascular disease that causes unique symptoms in each patient. Additional symptoms can include: