1 It also does not matter whether the syllables are stressed for the repetition of a consonant sound to count as consonance. 2  Alliteration is thus a special case of consonance, since it is restricted only to the beginning of words or in the beginning of a stressed syllable.
Most often, amitriptyline should be administered at a low dosage and slowly increased if need be. The maximum daily dosage for the majority of individuals is 150 mg. However, those who are patients in the hospital might consume up to 300 mg daily.
Half-life values range from 10 50 hours for amitriptyline and 20 100 hours for nortriptyline. Amitriptyline is metabolized in the liver to nortriptyline, which is lipophilic and crosses the blood-brain barrier. Amitriptyline and nortriptyline are distributed into the lungs, heart, brain, and liver.Nortriptyline is known to cross the placenta and is also distributed into breast milk.alf-life values range from 10 50 hours for amitriptyline and 20 100 hours for nortriptyline. Amitriptyline is metabolized in the liver to nortriptyline, which is lipophilic and crosses the blood-brain barrier. Amitriptyline and nortriptyline are distributed into the lungs, heart, brain, and liver.