You may have guessed that satiety is related to satisfy, satiate (meaning to satisfy fully or to excess), or sate (which means to glut or to satisfy to the full). If so, you guessed right. Satiety, along with the others, ultimately comes from the Latin word satis, which means enough..
Vesicant chemotherapy agents can be divided into two categories: DNA binding and DNA non-binding (see Table 1). Vesicants that bind to nucleic acids in DNA (eg, anthracylines) bind to the DNA in the cells of healthy tissue when they extravasate from the vein and promptly cause cell death. DNA-doxorubicin complexes are released from dead cells in the tissue and are taken up by adjacent healthy cells by endocytosis.
The penicillin-binding proteins, like the one shown on the left (PDB entry 3pte ), use a serine amino acid in their reaction, colored purple here. The serine forms a covalent bond with a peptidoglycan chain, then releases it as it forms the crosslink with another part of the peptidoglycan network. Penicillin binds to this serine but does not release it, thus permanently blocking the active site. Beta-lactamases, like the one shown on the right (PDB entry 4blm ), have a similar serine in their active site pocket. Penicillin also binds to this serine, but is then released in an inactivated form.