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Early symptoms of PV are common physical ailments and can be easily ignored by the patient. However, untreated PV may cause blood clots, which can lead to serious complications. Early symptoms of PV include: 1  fatigue. 2  difficulty breathing. 3  tingling in the hands and feet.
It usually affects the hip or knee. It can also occur in the shoulder, ankle, elbow, hand or foot. In PVNS the lining of the joint, called the synovium, becomes swollen and grows. This growth harms the bone next to the joint. The lining also makes extra fluid that can cause swelling and make movement painful. PVNS is idiopathic, it doesn't seem to run in families or be caused by certain jobs or activities. Surgery can help but, even with treatment, PVNS comes back about half the time. If the pain remains then radiation therapy may help.