1 If you are unhappy with your tattoo, having it altered or tattooed over might cost hundreds of dollars and removal is even more expensive-up to $10,000 in some cases. And some artists will charge extra for custom designs, but it is more common to ask for a deposit of about $50. 2  If you are unhappy with your tattoo, having it altered or tattooed over might cost hundreds of dollars and removal is even more expensive-up to $10,000 in some cases.
1 Single gene disorders are caused by a mutation in a single gene. 2  The mutation may be present on one or both chromosomes (one chromosome inherited from each parent). 3  Sickle cell disease, cystic fibrosis and gCJD are examples of single gene disorders.
Nonsense mutations can cause a genetic disease by damaging a gene responsible for a specific protein, for example, dystrophin in Duchenne muscular dystrophy. The same disease may, however, be caused by other kinds of damage to the same gene.