The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. Duchenne Muscular Dystrophy (DMD) is caused by deletion, duplication or point mutation of the dystrophin gene.Of the 7 exons most commonly deleted, 49,50 and 51 aooear to be the hot spots.
The Bethesda system (TBS) was developed by the United States National Cancer Institute (NCI) to provide more detailed information about Pap test results. When lab specialists examine cervical cells, they use this system to report the lab results to doctors. Your doctor gets the report from the lab.
Alarms and Events Reporting. An important feature of the BMS/EMS system is its Alarms and Events functionality. All alarms and events are time stamped and logged for long term retention and validation to 21 CFR Part 11. Individual plant data can be configured to have one or a combination of the following alarms: