Myelofibrosis (MF). 1  Is a rare bone marrow cancer. 2  Is a type of chronic leukemia and can occur on its own (primary myelofibrosis) or as a result of another bone marrow disorder. It is one of a related group of blood cancers known as âmyeloproliferative neoplasms (MPNs)â in which bone marrow cells that produce the blood cells develop and function abnormally. 2  The resulting fibrous scar tissue formation leads to severe anemia, weakness, fatigue and an enlarged spleen and liver.
A doughnut or donut (both: /ËdoÊnÉt/ or /ËdoÊnÊt/; see spelling differences) is a type of fried dough confectionery or dessert food.
Within the United States, the Providence metropolitan area was cited as having the most donut shops per capita (25.3 doughnut shops per 100,000 people) as of January 13, 2010.[80] National Doughnut Day celebrates the doughnut's history and role in popular culture.