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Top 10 Doctor insights on: How To Flush Macrobid Out Of System. 1 How long does Macrobid stay in your system after taking the last dosage? 24hours: Half life is 12 hours. That means the half of the total dose taken will be gone after 12 hours and then another 12 hours 50% from the other half will be gone and so forth.
Expired Macrobid. I have nitrofurantoin [Macrobid] I paid for but never used because I used to use an herb to treat a UTI. It's been in my fridge since I got it, but it says to discard after 2/25/2009. I know some things are still okay after the expiration date, but since it's an antibiotic I'm just not sure. It would save me a lot of money I don't have if I could just take that. It's Sunday so my doctor's office is closed.