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0. Phenobarbital is a barbiturate and will cause a positive test result for barbiturates. Phenytoin (Dilantin) is not a barbiturate; however a metabolite, p-hydroxyphenytoin has minimal cross reactivity on the initial screening test. There is no interfe.... Phenobarbital is a barbiturate and will cause a positive test result for barbiturates. Phenytoin (Dilantin) is not a barbiturate; however a metabolite, p-hydroxyphenytoin has minimal cross reactivity on the initial screening test. There is no interfe...
Barbiturates may be used for non-medical purposes to achieve a sedative effect. Long-acting barbiturates like phenobarbital may stay in the system for up to 140 hours, while short-acting barbiturates like Seconal may stay in the system for up to 40 hours, according to Drugs.com.