In patients with asthma, the total clearance offenoterol was 63 Â± 24 L/h and the steady-state volume of distribution was 140 Â± 70 L (62).Hochhaus et al. (62) suggested linear pharmacokinetics for fenoterol. There are nopublished pharmacokinetic studies with long-term use of fenoterol.
Toenail fungus, or onychomycosis, is an infection underneath the surface of the nail caused by fungi. When the tiny organisms take hold, the nail often becomes darker in color and smells foul. Debris may collect beneath the nail plate, white marks frequently appear on the nail plate, and the infection is capable of spreading to other toenails, the skin, or even the fingernails.
There are a host of factors that can cause thickened toenails, 1  Fungal infection of the toenail can result in thickened and yellow toenails. 2  In addition to thickening of the toenail, fungal infection can result in pain, burning and occasional bleeding from the toe. Fungal infection of the toenail can result in thickened and yellow toenails. 2  In addition to thickening of the toenail, fungal infection can result in pain, burning and occasional bleeding from the toe.