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Alpha-galactosidase is an enzyme, which is derived from the fungus Aspergillus niger. Itâs a homodimeric glycoprotein and it hydrolyzes the terminal alpha-galactosyl moieties (in chemistry moiety is defined as a functional group on a molecule) from glycolipids and glycoproteins.
Fig. 1 â beta-D-Galactopyranose. Galactose, sometimes abbreviated Gal, is a monosaccharide and the C4 epimer of glucose, that is, they differ only for the position of the-OH group on C4 (axial in Gal, equatorial in glucose).It has a sweetness equal to 33% of sucrose.n hepatocytes, galactose enters the Leloir pathway. Freed from lactose, the monosaccharide is mostly present as beta-isomer, and the first step of its hepatic metabolism is the conversion to the alpha-isomer, in the reaction catalyzed by galactose mutarotase (also known as aldose 1-epimerase).