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Transcript: Top 5 Causes of the Civil War. The American Civil War cost of 620,000 American lives, which is roughly only 1% of the African lives lost to the slave trade. However, to say the Civil War was fought over slavery is an over simplified answer. Here are the top five causes of the civil war.
Best Answer: Presidency and the Civil War Main article: Origins of the American Civil War With the emergence of the Republicans as the nation's first major sectional party by the mid-1850s, politics became the stage on which sectional tensions were played out.