Myelofibrosis (MF). 1  Is a rare bone marrow cancer. 2  Is a type of chronic leukemia and can occur on its own (primary myelofibrosis) or as a result of another bone marrow disorder. It is one of a related group of blood cancers known as âmyeloproliferative neoplasms (MPNs)â in which bone marrow cells that produce the blood cells develop and function abnormally. 2  The resulting fibrous scar tissue formation leads to severe anemia, weakness, fatigue and an enlarged spleen and liver.
A doughnut or donut (both: /ËdoÊnÉt/ or /ËdoÊnÊt/; see spelling differences) is a type of fried dough confectionery or dessert food.
In America, by contrast, donuts were embraced as an everyday food. Here, they took on the moniker donut, the first donut machine and chain store were spawned, and the treat became breakfast, as well as a snack to be eaten at any time.