The right common carotid artery arises from the brachiocephalic trunk (posterior to the right sternoclavicular joint), whereas the left common carotid is a branch of the arch of the aorta and hence has a thoracic portion before it reaches the neck (posterior to the left sternoclavicular joint).
Metformin Dosing. The recommended starting dosage of metformin is  500 mg twice daily. The maximum dosage for children age 10 to 16 is 2000 mg, and for adults age 17 and older is 2550 mg. Your dose should be increased only when necessary and should be increased slowly in order to avoid side effects.
And a recent study showed significant reduction in the prevalence and severity of fatty liver after 6 monthsâ treatment with 850 mg metformin twice daily in obese adolescents (Nadeau et al 2009). Metformin is an ideal drug for combination studies because of its safety and compatibility with other therapies.