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osteoblasts large, granular cells, can't undergo mitosis, found on surface of bone form bone, secrete the osteoid: collagen, proteoglycans, glycoproteins. Osteoblast are cuboidal mononuclear bone cells 15-30 Âµm in length, which form a contiguous monolayer over the surface of bone. They are derived from marrow stromal cells by differentiation of pre-osteoblasts and not themselves undergo mitosis.
Osteoblasts are bone-forming cells, have an extensive endoplasmic reticulum and numerous ribosomes. Ossification is the formation of bone by osteoblasts. Osteocytes become surrounded by bone matrix and are relatively inactive, but do have the capability to produce components needed to maintain the bone matrix if needed.