In order to understand why some combinations of alkyl halides and nucleophiles give a substitution reaction, whereas other combinations give elimination, and still others give no observable reaction, we must investigate systematically the way in which changes in reaction variables perturb the course of the reaction.
It's true - the ISS moves at about 17,000 mph (~28,000 kph). Now for your other questions: 1. When it's not using its onboard engines to adjust its orbit, the station is in free-fall*. This means that gravitational interaction with the earth maintains the station's orbit, and thus its speed.
First, the space shuttle is not designed or is able to go to the moon. It travels around the earth at about 250 miles altitude at around 17,500 miles per hour (around the earth in about 1 1/2 hours). The Apollo that did send men to the moon traveled at a maximum of 25,000 miles per hour, but the speed depended on where it was on the way to the moon.