Asylums: Essays on the Social Situation of Mental Patients and Other Inmates is a 1961 book by sociologist Erving Goffman.
Vmax is equal to the product of the catalyst rate constant (kcat) and the concentration of the enzyme. The Michaelis-Menten equation can then be rewritten as V= Kcat [Enzyme] [S] / (Km + [S]). Kcat is equal to K2, and it measures the number of substrate molecules turned over by enzyme per second.
Hi Arash, If you assume a constant rate of failure, then MTTF is the only parameter you need to estimate. Using the exponential distribution you can calculate the reliability at any point in time, R(t)=exp[-t/mttf] Making the assumption of constant failure rate the beta term is 1. If you have time to failure data, then fitting a Weibull to the data is one way to get the estimate of the beta and eta parameters.