Asylums: Essays on the Social Situation of Mental Patients and Other Inmates is a 1961 book by sociologist Erving Goffman.
Vmax is equal to the product of the catalyst rate constant (kcat) and the concentration of the enzyme. The Michaelis-Menten equation can then be rewritten as V= Kcat [Enzyme] [S] / (Km + [S]). Kcat is equal to K2, and it measures the number of substrate molecules turned over by enzyme per second.
The Michaelis constant Km is defined as the substrate concentration at 1/2 the maximum velocity. This is shown in Figure 8. Using this constant and the fact that Km can also be defined as: Km=K-1 + K2 / K+1. K+1, K-1 and K+2 being the rate constants from equation (7).