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osteoblasts large, granular cells, can't undergo mitosis, found on surface of bone form bone, secrete the osteoid: collagen, proteoglycans, glycoproteins. Osteoblast are cuboidal mononuclear bone cells 15-30 Âµm in length, which form a contiguous monolayer over the surface of bone. They are derived from marrow stromal cells by differentiation of pre-osteoblasts and not themselves undergo mitosis.
Bone Tumors. Bones are made of several different cell types, including cartilage, blood cells, fat, fibrous connective tissue and the calcium-depositing bone cells (osteoblasts). Any of these cell types are capable of developing into a tumor.