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The most prevalent of the stratified epithelia is the squamous variety. As a keratinized or waterproofed component of the skin, stratified squamous epithelium provides substantial protection against friction, microbial invasion and dessication.Keratinized stratified squamous epithelium is identified by the multiple layers of dead cells at the surface.s a keratinized or waterproofed component of the skin, stratified squamous epithelium provides substantial protection against friction, microbial invasion and dessication. Keratinized stratified squamous epithelium is identified by the multiple layers of dead cells at the surface.
1 Stratified signifies two or more layers of epithelial cells. 2  By convention, a stratified epithelium is described according to the shape of cells on its free surface. 3  Regardless of whether the surface cells are squamous, cuboidal, or columnar, the underlying cells are usually cuboidal. Within the epithelium, the narrow spaces between cells are sealed off from the external environment by cell junctions near the free surface of the cells. 2  Compared to ordinary connective tissue, epithelial tissue has very little interstitial fluid. 3  Epithelial tissue is polarized.