Specific enzymes called hydroxylases are responsible for these important reactions needed to form hydroxyproline and hydroxylysine. The hydroxylase enzymes require Vitamin C and Iron as cofactors. If a patient is Vitamin C deficient, then this reaction will not occur.n the extracellular spaces, another post-translational modification takes place as the triple helical collagen molecules (Figure 1) line up and begin to form fibrils and then fibers. This step is called crosslink formation and is promoted by another specialized enzyme called lysyl oxidase (Figure 3).
Here's the original Moody Blues as nobody knows them: Denny Laine - guitar, vocals; Clint Warwick - bass guitar; Mike Pinder - keyboards, notably Mellotron; Ray Thomas - guitar, flute, different thingamajigs; Graeme Edge - drums, dumb bits of dumb poetry.
Ironically, the Mellotron's usefulness ended right around the time Pinder left the Moody Blues. The group reconvened in 1978 for Octave after a four-year break. Pinder opted out of the supporting tour, and that was the end of his tenure with the band.