References: Titanium dioxide is the subject of new controversy, yet it is a substance as old as the earth itself. It is one of the top fifty chemicals produced worldwide. It is a white, opaque and naturally-occurring mineral found in two main forms: rutile and anatase.
Megestrol acetate (Megace Â®). Megestrol acetate is a hormonal therapy drug | most commonly used to treat breast cancer that has spread | . It is also sometimes used to treat womb or prostate cancer. Megestrol can also be used to improve symptoms such as hot flushes or loss of appetite.egestrol acetate (Megace Â®). Megestrol acetate is a hormonal therapy drug | most commonly used to treat breast cancer that has spread | . It is also sometimes used to treat womb or prostate cancer. Megestrol can also be used to improve symptoms such as hot flushes or loss of appetite.
In female beagles, megestrol acetate (0.01, 0.1, or 0.25 mg/kg/day) administered for up to 7 years induced both benign and malignant tumors of the breast. In female monkeys, no tumors were found following 10 years of treatment with 0.01, 0.1, or 0.5 mg/kg/day megestrol acetate. Pituitary tumors were observed in female rats treated with 3.9 or 10 mg/kg/day of megestrol acetate for 2 years.