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Except for some of the originally studied enzymes such as pepsin, rennin, and trypsin, most enzyme names end in ase. The International Union of Biochemistry (I.U.B.) initiated standards of enzyme nomenclature which recommend that enzyme names indicate both the substrate acted upon and the type of reaction catalyzed.xcept for some of the originally studied enzymes such as pepsin, rennin, and trypsin, most enzyme names end in ase. The International Union of Biochemistry (I.U.B.) initiated standards of enzyme nomenclature which recommend that enzyme names indicate both the substrate acted upon and the type of reaction catalyzed.
Following Buchner's example, enzymes are usually named according to the reaction they carry out: the suffix-ase is combined with the name of the substrate (e.g., lactase is the enzyme that cleaves lactose) or to the type of reaction (e.g., DNA polymerase forms DNA polymers).