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Peak levels and half life of LSD. LSD has a plasma half-life of 2.5-4 hours. The onset of LSD effects is rapid following intravenous administration (10 minutes) and slower when taken orally (20-30 minutes). LSD effects usually peak at 2-4 hours and gradually diminishing over 6-8 hours. Residual effects may last longer but usually resolve within 12 hours of dosing.
How long does it take for seizure medicines to reach the bloodstream? A dose of medication will reach a peak, or maximum, level in the blood 30 minutes to 4 or 6 hours after it is taken. The peak time varies for different drugs.