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Bacterial neutral proteases are active in a narrow pH range (pH 5 to 8) and have relatively low thermotolerance. Due to their intermediate rate of reaction, neutral proteases generate less bitterness in hydrolyzed food proteins than do the animal proteinases and hence are valuable for use in the food industry. Neutrase, a neutral protease, is insensitive to the natural plant proteinase inhibitors and is therefore useful in the brewing industry. The bacterial neutral proteases are characterized by their high affinity for hydrophobic amino acid pairs.
1 Most pathogenic bacteria grow at these temperatures. 2  Thermophilic bacteria. 3  These microorganisms grow at higher temperatures such as 110Â°F - 150Â°F. 4  Temperature is the most widely used method of controlling bacterial growth. However, many bacteria grow under either condition and they are facultative anaerobes. 2  Temperature -- Bacteria in general are capable of growing over a wide range of temperatures and are usually classified according to the temperature at which they grow.