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Hyperglycemia does it by increasing the rate of transformation of NAD to NADH. Hypoxia makes it difficult for cells to turn NADH back to NAD. In both conditions the increased NADH is recycled back to NAD by processes that produce free radicals, chemically reactive compounds that can damage tissue. Williamson and his coauthors propose that long-term use of these processes causes the damage seen in diabetes.
Diabetes affects the body in so many different ways. If you are suffering from diabetes then you need to consult with a medical specialist to find out how you can best manage your diabetes so that it does not lead to other debilitating ailments.ecause of the increased blood pressure, diabetes can also lead to a stroke. As well, diabetes also affects the eyes. Diabetes can cause the blood vessels in the back of eyes to swell and leak. This ailment is referred to as diabetic retinopathy.