ABSTRAL must be kept out of reach of children. [see Patient Counseling Information (17.1) and How Supplied/Storage and Handling (16.1)] The concomitant use of ABSTRAL with CYP3A4 inhibitors may result in an increase in fentanyl plasma concentrations, and may cause potentially fatal respiratory depression.
Renal osteodystrophy. Renal osteodystrophy or chronic kidney disease-mineral and bone disorder is a bone pathology, characterized by bone mineralization deficiency, that is a direct result of the electrolyte and endocrine derangements that accompany chronic kidney disease.
Anytime you hear the word 'renal', it means something pertaining to your kidneys, while 'corpuscle' means a 'small body'. But don't let the part about a small body fool you. What renal corpuscles lack in size, they make up for in significance. Renal corpuscles are the body's blood filtration mechanism, known as a nephron. Every day, the nephrons of your kidneys filter deadly toxins, such as nitrogenous wastes, a by-product of our metabolism, out of your blood.