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What Is a Clinical Trial? A clinical trial is a research program conducted with patients to evaluate a new medical treatment, drug, or device. The purpose of clinical trials is to find new and improved methods of treating, preventing, screening for, and diagnosing different diseases.
1 Positive trial -- The clinical trial shows that the new treatment has a large beneficial effect and is superior to standard treatment. 2  Non-inferior trial -- The clinical trial shows that that the new treatment is equivalent to standard treatment.3  Also called a non-inferiority trial.efinition of Clinical trials. Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.