CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc) is a multisystem connective tissue disorder.The acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.he acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Definition of devout. 1  1 : committed or devoted to religion or to religious duties or exercises a devout Catholic. 2  2 : expressing piety or religious fervor : expressing devotion a devout attitude.
Definition of shrine. 1a : a case, box, or receptacle; especially : one in which sacred relics (as the bones of a saint) are depositedb : a place in which devotion is paid to a saint or deity : sanctuaryc : a niche containing a religious image. 2 : a receptacle (as a tomb) for the dead.