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Genistein is a phytoestrogen and belongs to the category of isoflavones. Genistein was first isolated in 1899 from the dyer's broom, Genista tinctoria; hence, the chemical name. The compound structure was established in 1926, when it was found to be identical with prunetol.It was chemically synthesized in 1928.enistein has been used to selectively target pre B-cells via conjugation with an anti-CD19 antibody. Studies on rodents have found genistein to be useful in the treatment of leukemia, and that it can be used in combination with certain other antileukemic drugs to improve their efficacy.
Renin is a peptide hormone secreted by the kidneys. It functions in the renin-angiotensin system (RAS) which regulates extracellular fluid volume and arteriol blood pressure.As with other peptide hormones, the production and secretion of renin is tightly regulated by physiological processes within the body.fter renin is released from the kidney, it breaks down angiotensinogen into angiotensin I. This peptide is then broken down further into angiotensin II, which acts as a vasoconstrictor narrowing the blood vessels.