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You can do the math. Fentanyl lozenges-approx. 7 hours. Duragesic takes a few hours to kick in and is supposed to last up to 72 hours (like how Oxycontin is supposed to last 12 hours) but most people find it lasts 36-60 hours. From my experience I've found fentanyl patches to last about 48-54 hours.
Notes. 1  Heroin metabolizes to morphine very quickly--with a half-life of roughly 3 minutes. 2  The most quoted figure for the half-life of Fentanyl is 2 hours. 3  The 30 mg value is for the treatment of chronic pain, the 60 mg value is for the treatment of acute pain.