Agonists. Agonists bind to and activate receptors in a dose-dependent manner until all opioid receptors are occupied. At this point, the response plateau is reached, and increased doses of agonist have no effect. However, continued use beyond this plateau may lead to respiratory depression and overdose.ntagonists. Antagonists bind to the same receptors as full and partial agonists but do not cause activity at the receptor. Moreover, antagonists block agonists and partial agonists from binding and therefore prevent receptor activation altogether.
Tax Deductions for Voluntary Interest Payments on Student Loans. Most taxpayers who pay interest on student loans can take a tax deduction for the expense â and you can do this regardless of whether you itemize tax deductions on your return. The rules for claiming the deduction are the same whether the interest payments were required or voluntary.
How much of the SEP contributions are deductible? The most you can deduct on your businessâs tax return for contributions to your employeesâ SEP-IRAs is the lesser of your contributions or 25% of compensation. (Compensation considered for each employee is limited and subject to annual cost-of-living adjustments).f the SEP-IRA permits non-SEP contributions, you can make regular IRA contributions (including IRA catch-up contributions if you are age 50 and older) to your SEP-IRA, up to the maximum annual limit.