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It is a very hygroscopic colourless solid that is soluble in water and polar organic solvents. Tetramethylammonium chloride is a major industrial chemical, being used in such processes as hydrofracking.In the laboratory, it has fewer synthetic chemical applications than quaternary ammonium salts containing longer N-alkyl substituents, which are used extensively as phase-transfer catalysts.t is a very hygroscopic colourless solid that is soluble in water and polar organic solvents. Tetramethylammonium chloride is a major industrial chemical, being used in such processes as hydrofracking.
Common nomenclature [edit]. In the toxicological literature, naturally-occurring tetramethylammonium (anion unspecified) is often referred to by the name tetramine.Unfortunately, this non-systematic or trivial name is also used for other chemical entities, including a toxic rodenticide (Tetramethylenedisulfotetramine).D 50 for TMA chloride: 25 mg/kg (mouse, i.p.); 40 mg/kg (mouse, s.c.). LC 50 for TMA chloride: 462 mg/L for 96 hrs. (Fathead minnow, Pimephales promelas).