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Medical Definition of anaplasma. 1  1 capitalized : a genus of parasitic, gram-negative, nonmotile bacteria of the family Anaplasmataceae that are transmitted chiefly by ticks and biting flies and infect the red blood cells of humans and animalsâsee anaplasmosis. 2  2plural anaplasmas or anaplasmata \-mÉt-É\play : any bacterium of the genus Anaplasma.
Human granulocytic anaplasmosis (HGA) is an infection caused by the bacteria Anaplasma phagocytophilum.HGA bacteria infect the white blood cells of their hosts, specifically the granulocytes. In California, people get HGA when they are bitten by a western black-legged tick infected with HGA bacteria.GA is rarely fatal. Most individuals infected with HGA bacteria have no or mild symptoms. When symptoms occur, they resemble the flu, with fever, headache, fatigue, muscle aches, and nausea. Some individuals may also have vomiting, cough, or a rash.