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Since the first therapeutic application of a r-protein produced in mammalian cells was approved in 1986. (human tissue plasminogen activator, tPA, Genentech), biopharmaceuticals have changed the. landscape for the treatment of many diseases, including many types of cancer, rheumatic conditions. and orphan diseases.
Best Answer: Pepsin is a protease produced by the stomach. Trypsin and chymotrypsin are proteases produced by the pancreas that function in the duodenum. Proteases (proteinases, peptidases, or proteolytic enzymes) are enzymes that break peptide bonds between amino acids of proteins. The process is called proteolytic cleavage, a common mechanism of activation or inactivation of enzymes, especially those involved in blood coagulation or digestion.