Clinical Significance. Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder obstruction. The assessment of direct bilirubin is helpful in the differentiation of hepatic disorders.
Rhythm and Blues Music: Overview. and blues (R&B), which combines soulful singing and a strong backbeat, was the most popular music created by and for African Americans between the end of World War II (1941-45) and the early 1960s. Such Georgia artists as Ray Charles, Little Richard, and James Brown rank among the most influential and innovative R&B performers.
Funk originated in the mid-1960s, with James Brown 's development of a signature groove that emphasized the downbeat âwith heavy emphasis on the first beat of every measure, funky bass lines, drum patterns, and syncopated guitar riffs.