CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc) is a multisystem connective tissue disorder.The acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.he acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Definition of devout. 1  1 : committed or devoted to religion or to religious duties or exercises a devout Catholic. 2  2 : expressing piety or religious fervor : expressing devotion a devout attitude.
Holy has the idea of heaviness or weight of glory. In the New Testament, the word for holy is âhagiosâ and means set apart, reverend, sacred, and worthy of veneration.â This word applies to God because God Himself is totally other, separate, sacred, transcendent, reverend, and set apart from every created thing.