CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc) is a multisystem connective tissue disorder.The acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.he acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Definition of devout. 1  1 : committed or devoted to religion or to religious duties or exercises a devout Catholic. 2  2 : expressing piety or religious fervor : expressing devotion a devout attitude.
Definition of pious. 1  1a : marked by or showing reverence for deity and devotion to divine worshipb : marked by conspicuous religiosity a hypocriteâa thing all pious words and uncharitable deeds â Charles Reade. 2  2 : sacred or devotional as distinct from the profane or secular : religious a pious opinion.