1 Other symptoms may accompany the rash, such as joint pain, fever, chills, or fatigue. 2  If Lyme disease is not treated, more severe symptoms and complications can occur. 3  These include arthritis, neurologic symptoms, or heart problems.ymptoms. 1  A bull's-eye rash (erythema migrans) is the most definitive sign of Lyme disease infection. 2  Other symptoms may accompany the rash, such as joint pain, fever, chills, or fatigue. 3  If Lyme disease is not treated, more severe symptoms and complications can occur.
Dopamine production. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. It is a neurohormone that is released by the hypothalamus.
Dopamine in movement. A part of the brain called the basal ganglia regulates movement. Basal ganglia in turn depend on a certain amount of dopamine to function at peak efficiency. The action of dopamine occurs via dopamine receptors, D1-5. Dopamine reduces the influence of the indirect pathway, and increases the actions of the direct pathway within the basal ganglia.