Despite an increase in the number of available and effective antidepressants, many patients with depression respond poorly to drug treatment. At least a third of patients make an inadequate response to their first antidepressant monotherapy. Responses to subsequent courses are also limited.
Epidemiology/ Etiology. Discogenic pain is a form of low back pain, caused by chemically or mechanically damaged intervertebral discs.(level: 3A) This damage can find its origin in traumatic events, as well as in deterioration due to aging.
Causes of cervicalgia neck pain. Nerves, bones, discs, muscles, ligaments, and joints â all the cervical structures can cause neck pain when they are irritated or inflamed. How does this happen? The list below covers cervicalgia causes. Injury/trauma: During accidents, people can experience whiplash. This type of injury is a hyperextension of the neck because the head is forced to move either forward or backward beyond the neckâs normal range of movement.