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Human coccidiosis is produced by species of Isospora; in its severe form it is characterized by diarrhea (sometimes alternating with constipation), fever, abdominal pain, nausea, headache, loss of appetite, and loss of weight.
Signs of coccidiosis are usually worst following stressful periods such as weather changes, weaning, overcrowding, long travel, filthy surroundings or other illnesses such as shipping fever. In mild cases, animals may be asymptomatic, or may only show mild diarrhea, and exhibit a rough haircoat .