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Peak levels and half life of LSD. LSD has a plasma half-life of 2.5-4 hours. The onset of LSD effects is rapid following intravenous administration (10 minutes) and slower when taken orally (20-30 minutes). LSD effects usually peak at 2-4 hours and gradually diminishing over 6-8 hours. Residual effects may last longer but usually resolve within 12 hours of dosing.
A powerful hallucinogen, LSD can stay in your system and be detected up to 5 days after use. Although it is not physically addictive, LSD use can lead to repeated dosing and psychotic effects. More on what happens in the body when you take LSD below.