Despite an increase in the number of available and effective antidepressants, many patients with depression respond poorly to drug treatment. At least a third of patients make an inadequate response to their first antidepressant monotherapy. Responses to subsequent courses are also limited.
Epidemiology/ Etiology. Discogenic pain is a form of low back pain, caused by chemically or mechanically damaged intervertebral discs.(level: 3A) This damage can find its origin in traumatic events, as well as in deterioration due to aging.
Are located outside of the lining of the uterus and protrude outward. They have less of an effect on your period, but may cause back pain or bladder pressure. Subserosal and submucosal fibroid can also grow on a stalk attached to the uterus, in which case it is called âpendunculated.â The stalk may become twisted and can cause severe pelvic pain.