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You can do the math. Fentanyl lozenges-approx. 7 hours. Duragesic takes a few hours to kick in and is supposed to last up to 72 hours (like how Oxycontin is supposed to last 12 hours) but most people find it lasts 36-60 hours. From my experience I've found fentanyl patches to last about 48-54 hours.
Read More. For me, it was different than some of the folks who comment that took pills orally. Fentanyl is extemely strong, it stays in your system for a long time as it is deposited into you fat cells, etc. That is the way I understand to have read it. I don't want to discourage you but for me, I just got better after day 18.