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Overview of Xylazine for Dogs and Cats. 1  Xylazine, commonly known as Rompun, belongs to a class of drugs known as alpha 2 adrenergic agonists and is similar to clonidine. 2  It is a sedative that provides pain relief as well as muscle relaxation to dogs.
1 For sedation in dogs and cats, xylazine is dosed at 0.25 to 0.5 mg per pound (0.5 to 1 mg/kg) intravenous or 0.5 to 1 mg per pound (1 to 2 mg/kg) intramuscular or subcutaneous.