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Histones are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin. Nuclear DNA does not appear in free linear strands; it is highly condensed and wrapped around histones in order to fit inside of the nucleus and take part in the formation of chromosomes.nder the microscope in its extended form, chromatin looks like beads on a string. The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer.
There are four types of histones found in chromatin: H2A, H2B, H3, and H4. Two of each histone comprise a protein core, a nucleosome, which DNA wraps around twice.What results is a bead on a string model in which the nucleosomes are the beads and the linker DNA binds them together.Another characteristic of histones are the protein tails that extend outward from the bead..The tails and the degree of their acetylation is an important factor in gene expression.here are four types of histones found in chromatin: H2A, H2B, H3, and H4. Two of each histone comprise a protein core, a nucleosome, which DNA wraps around twice.