ABSTRAL must be kept out of reach of children. [see Patient Counseling Information (17.1) and How Supplied/Storage and Handling (16.1)] The concomitant use of ABSTRAL with CYP3A4 inhibitors may result in an increase in fentanyl plasma concentrations, and may cause potentially fatal respiratory depression.
Renal osteodystrophy. Renal osteodystrophy or chronic kidney disease-mineral and bone disorder is a bone pathology, characterized by bone mineralization deficiency, that is a direct result of the electrolyte and endocrine derangements that accompany chronic kidney disease.
Osteochondrodystrophy, Focal Osteodystrophy, Cartilage Plug. Tibial dyschondroplasia (TD) is a common skeletal bone deformity that affects the long bones in the chicken's leg. It involves the development of an abnormal mass of cartilage at the growth plate of the long bones of the leg, usually the tibia bone. Instead of calcifying, the cartilage remains soft and will often bend backwards under pressure or heavy body weight.