Certain genes playing a key role in specification of pigment cell fates from the neural crest have been well characterized. At the core of melanocyte fate specification is the transcriptional activator microphthalmia-associated transcription factor (MITF; Mitfa in zebrafish).
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fenfluramine A drug used in the management of obesity. It is thought to work by producing a sense of having eaten enough (satiety) rather than by suppressing appetite. There is evidence that fenfluramine may be associated with heart valve disease and PULMONARY HYPERTENSION and it is now rarely used. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the webmaster's page for free fun content.