Specific enzymes called hydroxylases are responsible for these important reactions needed to form hydroxyproline and hydroxylysine. The hydroxylase enzymes require Vitamin C and Iron as cofactors. If a patient is Vitamin C deficient, then this reaction will not occur.n the extracellular spaces, another post-translational modification takes place as the triple helical collagen molecules (Figure 1) line up and begin to form fibrils and then fibers. This step is called crosslink formation and is promoted by another specialized enzyme called lysyl oxidase (Figure 3).
Here's the original Moody Blues as nobody knows them: Denny Laine - guitar, vocals; Clint Warwick - bass guitar; Mike Pinder - keyboards, notably Mellotron; Ray Thomas - guitar, flute, different thingamajigs; Graeme Edge - drums, dumb bits of dumb poetry.
Dennis DeYoung. Dennis DeYoung (born February 18, 1947) is an American singer, songwriter, musician and producer best known for being a founding member of the rock band Styx as lead vocalist and keyboardist, a tenure that lasted from 1970 until June 1999. DeYoung has been credited as the writer of more Styx songs than any other Styx member.