Rosa Parks was born Rosa Louise McCauley in Tuskegee, Alabama, on February 4, 1913, to Leona (nÃ©e Edwards), a teacher, and James McCauley, a carpenter. She was of African ancestry, though one of her great-grandfathers was Scots-Irish and one of her great-grandmothers was a slave of Native American descent.
Fentanyl (also known as fentanil) is a potent, synthetic opioid pain medication with a rapid onset and short duration of action. It is a potent agonist at Î¼-opioid receptors in the brain. Fentanyl is 50 to 100 times more potent than morphine, but some fentanyl analogues, which are designed to mimic the pharmacological effects of the original drug, may be as much as 10,000 times more potent than morphine.
The estimated lethal dose of fentanyl in humans is 2 mg. The recommended serum concentration for analgesia is 1â2 ng/ml and for anaesthesia it is 10â20 ng/ml. Blood concentrations of approximately 7 ng/ml or greater have been associated with fatalities where poly-substance use was involved.