Agonists. Agonists bind to and activate receptors in a dose-dependent manner until all opioid receptors are occupied. At this point, the response plateau is reached, and increased doses of agonist have no effect. However, continued use beyond this plateau may lead to respiratory depression and overdose.ntagonists. Antagonists bind to the same receptors as full and partial agonists but do not cause activity at the receptor. Moreover, antagonists block agonists and partial agonists from binding and therefore prevent receptor activation altogether.
Tax Deductions for Voluntary Interest Payments on Student Loans. Most taxpayers who pay interest on student loans can take a tax deduction for the expense â and you can do this regardless of whether you itemize tax deductions on your return. The rules for claiming the deduction are the same whether the interest payments were required or voluntary.
But you can deduct only premiums that you pay with after-tax money from your own pocket. For example: If your health insurance premiums are paid entirely by your employer or the government, you cannot deduct the cost. If you have health insurance through your employer and your share of the premium is deducted from your paycheck pre-tax, you cannot deduct the cost because the premiums were tax-free already. If you don't know whether you pay pre-tax or after-tax, ask your human resources department.