Certain genes playing a key role in specification of pigment cell fates from the neural crest have been well characterized. At the core of melanocyte fate specification is the transcriptional activator microphthalmia-associated transcription factor (MITF; Mitfa in zebrafish).
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Tetrahydrofuran (THF) is an organic compound with the formula (CH 2) 4 O. The compound is classified as heterocyclic compound, specifically a cyclic ether. It is a colorless, water-miscible organic liquid with low viscosity.It is mainly used as a precursor to polymers.n the laboratory, THF is a popular solvent when its water miscibility is not an issue. It is more basic than diethyl ether and forms stronger complexes with Li + , Mg 2+ , and boranes. It is a popular solvent for hydroboration reactions and for organometallic compounds such as organolithium and Grignard reagents.