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Since the first therapeutic application of a r-protein produced in mammalian cells was approved in 1986. (human tissue plasminogen activator, tPA, Genentech), biopharmaceuticals have changed the. landscape for the treatment of many diseases, including many types of cancer, rheumatic conditions. and orphan diseases.
Report Abuse. proteins r made of all the 20 known aminoacids.aminoacids occur at different combinations and at different numbers in each proetein and r unique to that protein. as some aminoacids repeat themselves at various positions and to establish the exact positions of each amino acid this kind of numbering is used.