Despite an increase in the number of available and effective antidepressants, many patients with depression respond poorly to drug treatment. At least a third of patients make an inadequate response to their first antidepressant monotherapy. Responses to subsequent courses are also limited.
Epidemiology/ Etiology. Discogenic pain is a form of low back pain, caused by chemically or mechanically damaged intervertebral discs.(level: 3A) This damage can find its origin in traumatic events, as well as in deterioration due to aging.
These often occur after lifting something heavy. Other causes of low back pain include a slipped disc, spinal stenosis, and degenerative disc disease (among many others). None of these causes of low back pain are associated with diarrhea. Diarrhea is most often caused by some dietary issue that you GI tract does not agree with or a GI infection. Sometimes diarrhea can cause severe pain, but this pain is most often located in your abdomen (not in your back). Thus, I would say that the two are unlikely to be related.