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Medical Definition of anaplasma. 1  1 capitalized : a genus of parasitic, gram-negative, nonmotile bacteria of the family Anaplasmataceae that are transmitted chiefly by ticks and biting flies and infect the red blood cells of humans and animalsâsee anaplasmosis. 2  2plural anaplasmas or anaplasmata \-mÉt-É\play : any bacterium of the genus Anaplasma.
Three of the most common signs of anaplasmosis are lethargy, loss of appetite, and fever. These are common signs of many diseases. Other signs that may be seen include pale mucous membranes (e.g., pale gums), vomiting, diarrhea, lameness, nosebleeds, and dark stools (due to the presence of digested blood). Often these symptoms are noticed in spring and fall, when ticks are most abundant.