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Great Saphenous Vein. This vein is a conjunction of the dorsal vein of the great toe and the dorsal venous arch of the foot. It travels up the leg, in front of the inner ankle protruberance (anterior to the medial malleolus), and ascends all the way up the lower limb on the inner aspect leg and thigh (anteromedial aspect).
These are some of the more common causes of lower leg pain from problems with blood vessels: Blood clot. A blood clot that develops in a vein deep in the body is called deep vein thrombosis (DVT). Most deep vein blood clots develop in the lower leg or thigh.