You only need the English Proficient for international operations as it's an ICAO thing. Some countries, like France, check; others may not. Similar on the RRTO -- some countries, like Canada and the Bahamas don't require it, but others, like Turks & Caicos, do require it and do check it.
Apoptosis: A form of cell death in which a programmed sequence of events leads to the elimination of cells without releasing harmful substances into the surrounding area. Apoptosis plays a crucial role in developing and maintaining the health of the body by eliminating old cells, unnecessary cells, and unhealthy cells.
When a death signal is received by the cell, it overrides the brake, and the apoptotic pathway activates proteases and nucleases, enzymes that cut up the protein and DNA of the cell. The main proteases of apoptosis are called caspases; in the nematode, the chief caspase is Ced-3.