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The medical abbreviation for once a week is qw. qw or qwk is used for every week. The medical abbreviation for once a week is qw. qw or qwk is used for every week.
PRN is a Latin abbreviation which means Pro Re Nata, translated in English as as needed. Example, analgesics like acetaminophen for headache. Normally, it is supposed to be taken every 6 hours, but when the headache disappears, you stop taking it. That is what PRN is all about.