1 Other symptoms may accompany the rash, such as joint pain, fever, chills, or fatigue. 2  If Lyme disease is not treated, more severe symptoms and complications can occur. 3  These include arthritis, neurologic symptoms, or heart problems.ymptoms. 1  A bull's-eye rash (erythema migrans) is the most definitive sign of Lyme disease infection. 2  Other symptoms may accompany the rash, such as joint pain, fever, chills, or fatigue. 3  If Lyme disease is not treated, more severe symptoms and complications can occur.
Dopamine production. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. It is a neurohormone that is released by the hypothalamus.
If excess amounts of dopamine are ingested, the body will regulate the amount of dopamine in the brain within several hours; however, if symptoms such as muscle spasms, shaking hands or an irregular heartbeat are experienced, medical attention should be sought immediately.