Certain genes playing a key role in specification of pigment cell fates from the neural crest have been well characterized. At the core of melanocyte fate specification is the transcriptional activator microphthalmia-associated transcription factor (MITF; Mitfa in zebrafish).
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CLICK HERE to learn more about from eMedTV.com. Vagifem Â® (estradiol vaginal tablets) is a prescription medication that contains an estrogen hormone. It is used to treat dryness, itching, and burning in and around the vagina, usually in postmenopausal women.It is inserted vaginally using a special applicator. Your Vagifem package comes with detailed instructions on how to use the tablets. 2  Dispose of the applicator just as you would a plastic tampon applicator (do not flush it). 3  Vagifem is typically used daily for the first two weeks; after that, it is usually used just twice a week.