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Mesquite is a leguminous plant of the Prosopis genus found in northern Mexico through the Sonoran Desert and Chihuahuan Deserts, and up into the Southwestern United States as far north as southern Kansas, west to the Colorado Desert in California, and east to the eastern fifth of Texas, where average annual rainfall is in excess of 40 in.
Europeans noted use of peyote in Native American religious ceremonies upon early contact, notably by the Huichols in Mexico. Other mescaline-containing cacti such as the San Pedro have a long history of use in South America, from Peru to Ecuador.In traditional peyote preparations, the top of the cactus is cut at ground level, leaving the large tap roots to grow new heads.These heads are then dried to make disc-shaped buttons.escaline is legal only for certain religious groups (such as the Native American Church) and in scientific and medical research. In 1990, the Supreme Court ruled that the state of Oregon could bar the use of mescaline in Native American religious ceremonies.