1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
Physical effects. Alcohol doesnât only affect your mood; it also has an effect on your body. After you drink alcohol it gets into your bloodstream. The blood carries it to every part of your body. Thus, your entire body is affected by drinking alcohol. To learn more about the effects of alcohol on the body, click here alcohol and your body.