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Most often, colon cancer spreads to the liver, but it can also spread to the ovaries, lungs, or brain. Colon cancer tends to spread to the liver first, because all of the blood from the colon drains to the liver before proceeding to the rest of the body.
When prostate cancer spreads beyond the prostate to another organ, most frequently it spreads to the bone. Prostate cancer that spread to the bone is still prostate cancer when doctors look at it under the microscope. It is still treated with therapy for prostate cancer. A man whose prostate cancer spread to the bone does not have bone cancer.