1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
The short-term effects of alcohol are dependent on how much alcohol is consumed, and thus how much alcohol is in the blood (the blood alcohol level).here are a few long-term effects of alcohol that are beneficial, however. When alcohol is consumed in the recommended amounts, the following physical effects of alcohol are seen: 1  Reduced risk of death from coronary heart disease. 2  Reduced risk of blood clot.