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You can do the math. Fentanyl lozenges-approx. 7 hours. Duragesic takes a few hours to kick in and is supposed to last up to 72 hours (like how Oxycontin is supposed to last 12 hours) but most people find it lasts 36-60 hours. From my experience I've found fentanyl patches to last about 48-54 hours.
it takes up to 15 mins for your body to dissolve the methadone into your system it can take up to 7 days to come out of your urine and months to come out of your system all together they say methadone doesnt go into your bones but take it from someone who knows it takes months to come off it fully so unless you really need it DONT TOUCH IT its not worth it i went trough hell for 3 months over 2 months with little or no sleep off a 100mill programme i wouldnt wish it on my worst enemy.