Despite an increase in the number of available and effective antidepressants, many patients with depression respond poorly to drug treatment. At least a third of patients make an inadequate response to their first antidepressant monotherapy. Responses to subsequent courses are also limited.
Epidemiology/ Etiology. Discogenic pain is a form of low back pain, caused by chemically or mechanically damaged intervertebral discs.(level: 3A) This damage can find its origin in traumatic events, as well as in deterioration due to aging.
A. Pancreatic pain can sometimes cause refferred pain to the waist and back in a belt-shape form. This is due to the nerve supply to the pancreas and its origin. I would also recommend to get an ultrasound of the kidney just to make sure there is no pathology there. More discussions about flank pain.