1 Other symptoms may accompany the rash, such as joint pain, fever, chills, or fatigue. 2  If Lyme disease is not treated, more severe symptoms and complications can occur. 3  These include arthritis, neurologic symptoms, or heart problems.ymptoms. 1  A bull's-eye rash (erythema migrans) is the most definitive sign of Lyme disease infection. 2  Other symptoms may accompany the rash, such as joint pain, fever, chills, or fatigue. 3  If Lyme disease is not treated, more severe symptoms and complications can occur.
Dopamine production. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. It is a neurohormone that is released by the hypothalamus.
Scientists call the link between the drug and the receptor a lock and key relationship, because one specific neurotransmitter activates specific receptor molecules, the same way only one key fits a particular lock. When the opiates reach the opiate receptors, the latter release the hormone dopamine. The dopamine â which acts as an âexcitatory neurotransmitterâ â produces feelings of pleasure and satisfaction. Itâs this action at the most basic cellular level that provides the foundation for drug addiction. Young recovering heroin addicts Tej Yaich, 20, Holly Yates, 20 and Tara McCormac, 22, and Dr. Joseph Gay share their stories and discuss the growing heroin crisis in Ohio.