Agonists. Agonists bind to and activate receptors in a dose-dependent manner until all opioid receptors are occupied. At this point, the response plateau is reached, and increased doses of agonist have no effect. However, continued use beyond this plateau may lead to respiratory depression and overdose.ntagonists. Antagonists bind to the same receptors as full and partial agonists but do not cause activity at the receptor. Moreover, antagonists block agonists and partial agonists from binding and therefore prevent receptor activation altogether.
Tax Deductions for Voluntary Interest Payments on Student Loans. Most taxpayers who pay interest on student loans can take a tax deduction for the expense â and you can do this regardless of whether you itemize tax deductions on your return. The rules for claiming the deduction are the same whether the interest payments were required or voluntary.
If neither you nor your spouse is covered by a retirement plan at work, your deduction is allowed in full. For contributions to a traditional IRA, the amount you can deduct may be limited if you or your spouse is covered by a retirement plan at work and your income exceeds certain levels.Roth IRA contributions arenât deductible.ee the discussion of IRA Contribution Limits. If you or your spouse is covered by an employer-sponsored retirement plan and your income exceeds certain levels, you may not be able to deduct your entire contribution. See the discussion of IRA deduction limits.