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Report Abuse. When I have taken Vicodin...It would take about 20 minutes for it to kick-in....I know that depending on what dose you are taking and how bad your pain is can also effect how long it takes to kick-in... Chi Town Jaki Â· 8 years ago. Thumbs up.
The relative milligram strength of hydrocodone to codeine is given as 6 fold, that is 5 mg has the effect of 30 mg of codeine; by way of the Roman numeral VI this is said to have given rise to the trade name Vicodin. [citation needed] Pharmacokinetics. Hydrocodone is only pharmaceutically available as an oral drug. The onset of action of hydrocodone via this route is 10 to 20 minutes, with a peak effect (T max) occurring at 30 to 60 minutes, and it has a duration of 4 to 8 hours. Metabolism