Agonists. Agonists bind to and activate receptors in a dose-dependent manner until all opioid receptors are occupied. At this point, the response plateau is reached, and increased doses of agonist have no effect. However, continued use beyond this plateau may lead to respiratory depression and overdose.ntagonists. Antagonists bind to the same receptors as full and partial agonists but do not cause activity at the receptor. Moreover, antagonists block agonists and partial agonists from binding and therefore prevent receptor activation altogether.
Tax Deductions for Voluntary Interest Payments on Student Loans. Most taxpayers who pay interest on student loans can take a tax deduction for the expense â and you can do this regardless of whether you itemize tax deductions on your return. The rules for claiming the deduction are the same whether the interest payments were required or voluntary.
You can deduct half of the cost of your meals, or if you donât want to keep a lot of records, you can base your deduction on the standard meal allowance for federal workers, which is $46 per day, as of tax year 2012.Special rates may apply for exceptionally expensive areas.f you take your own car, you can either deduct the standard federal mileage rate (55Â½ cents per mile, as of this writing in March of 2013), or you can deduct actual expenses. You can also deduct rental car fees.