1 Other symptoms may accompany the rash, such as joint pain, fever, chills, or fatigue. 2  If Lyme disease is not treated, more severe symptoms and complications can occur. 3  These include arthritis, neurologic symptoms, or heart problems.ymptoms. 1  A bull's-eye rash (erythema migrans) is the most definitive sign of Lyme disease infection. 2  Other symptoms may accompany the rash, such as joint pain, fever, chills, or fatigue. 3  If Lyme disease is not treated, more severe symptoms and complications can occur.
Dopamine production. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. It is a neurohormone that is released by the hypothalamus.
Lets start with the basics. Dopamine is a neurotransmitter, one of those chemicals that is responsible for transmitting signals in between the nerve cells (neurons) of the brain. Very few neurons actually make dopamine. Some, in a part of the brain called the substantia nigra, are the cells that die during Parkinsons disease.