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You can do the math. Fentanyl lozenges-approx. 7 hours. Duragesic takes a few hours to kick in and is supposed to last up to 72 hours (like how Oxycontin is supposed to last 12 hours) but most people find it lasts 36-60 hours. From my experience I've found fentanyl patches to last about 48-54 hours.
Read More. How long does it take for the synthetic hormones to get out of your body once you STOP taking the pill? My doctor wants me to stop and then get blood work done in 2 weeks to see if I am in peri menopause. Two weeks doesn't seem very long since I have been on the pill for over 20 years.