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peroxisome (plural peroxisomes) An intracellular organelle found in all eukaryotes (except Archezoa) which is the source of the enzymes that catalyze the production and breakdown hydrogen peroxide, and are responsible for the oxidation of long-chain fatty acids. Synonyms . microbody; Derived terms . peroxisomal
A major function of the peroxisome is the breakdown of very long chain fatty acids through beta-oxidation. In animal cells, the long fatty acids are converted to medium chain fatty acids, which are subsequently shuttled to mitochondria where they are eventually broken down to carbon dioxide and water.eroxisomes contain oxidative enzymes, such as catalase, D-amino acid oxidase, and uric acid oxidase. However the last enzyme is absent in humans, explaining the disease known as gout, caused by the accumulation of uric acid.