Specific enzymes called hydroxylases are responsible for these important reactions needed to form hydroxyproline and hydroxylysine. The hydroxylase enzymes require Vitamin C and Iron as cofactors. If a patient is Vitamin C deficient, then this reaction will not occur.n the extracellular spaces, another post-translational modification takes place as the triple helical collagen molecules (Figure 1) line up and begin to form fibrils and then fibers. This step is called crosslink formation and is promoted by another specialized enzyme called lysyl oxidase (Figure 3).
Here's the original Moody Blues as nobody knows them: Denny Laine - guitar, vocals; Clint Warwick - bass guitar; Mike Pinder - keyboards, notably Mellotron; Ray Thomas - guitar, flute, different thingamajigs; Graeme Edge - drums, dumb bits of dumb poetry.
Disturbed is an American heavy metal band from Chicago, Illinois. The band comprises vocalist David Draiman, bassist John Moyer, guitarist Dan Donegan, and drummer Mike Wengren. Former band members are vocalist Erich Awalt and bassist Steve Kmak. Formed in 1994 as Brawl, the band was renamed Disturbed in 1996 after Draiman was hired as the band's new vocalist. The band has released six studio albums, five of which have consecutively debuted at No. 1 on the Billboard 200.