Certain genes playing a key role in specification of pigment cell fates from the neural crest have been well characterized. At the core of melanocyte fate specification is the transcriptional activator microphthalmia-associated transcription factor (MITF; Mitfa in zebrafish).
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A 'Slipped Upper Femoral Epiphysis' (also called a 'SUFE') is a condition involving the hip joint. The hip joint works as a ball and socket.With a SUFE, the growth plate (called the epiphyseal plate) at the top of the thigh bone is weak and the ball (head of the femur) slips downward and backward.he exact cause of this condition is not known, but there may be a link between increased weight and puberty hormones. A 'SUFE' is not usually associated with an injury. The symptoms often develop slowly-over several months-and may seem like a pulled muscle in the hip, thigh or knee.