During the last decade, the efficacy of arsenic trioxide in both newly diagnosed and relapsed patients with APL 3 has been established. Arsenic trioxide can be used as a single agent and induces complete remissions with only minimal myelosuppression (1) (2, 3, 4, 5) . In one study (2) (1) .Additional studies conducted in the United States confirmed that low doses of arsenic trioxide can induce complete remission in relapsed APL patients.hite arsenic or arsenic trioxide (As 2 O 3) is produced by heating realgar (10) . Arsenic is rarely found in a pure state; rather, it exists in both trivalent and pentavalent oxidation states as a chemically unstable sulfide or oxide, or as a salt of sodium, potassium, or calcium (11) .
The most common statin side effects include: 1  Headache. 2  Difficulty sleeping. 3  Flushing of the skin.  Muscle aches, tenderness, or weakness 1  (myalgia) Drowsiness. 2  Dizziness. Nausea or vomiting.  Abdominal cramping 1  or pain. Bloating 2  or gas. 3  Diarrhea. Constipation.  Rash.
People who use statin drugs to lower their cholesterol sometimes complain of muscle pain and soreness. But a new study suggests that in some cases these side effects may be a result of combining statins with other medications.he research found that people taking statins had double the risk of muscle pain when they were prescribed various other drugs, and often these side effects were what prompted people to stop taking statins.