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You can do the math. Fentanyl lozenges-approx. 7 hours. Duragesic takes a few hours to kick in and is supposed to last up to 72 hours (like how Oxycontin is supposed to last 12 hours) but most people find it lasts 36-60 hours. From my experience I've found fentanyl patches to last about 48-54 hours.
Below is a guide to what Fentanyl is and how long it stays in your system. The Composition and Uses of Fentanyl. In order to analyze how your body breaks down and processes Fentanyl, it is necessary to first understand what Fentanyl is and how it interacts with the body.