1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
Other short term effects of alcohol include harm to the bodyâs tissues: 1  Stomach: Alcohol irritates the stomach and intestine lining and increases stomach acid secretion. This causes vomiting. 2  Skin: Alcohol increases blood flow to the skin, causing users to sweat and appear flushed.