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Adj. 1. immiscible - (chemistry, physics) incapable of mixing. non-miscible, unmixable. natural philosophy, physics-the science of matter and energy and their interactions; his favorite subject was physics.
â¢ Soluble means capable of dissolving in a solvent whereas insoluble means incapable of dissolving in a solvent. â¢ Polar and non-polar substances are soluble in polar and non-polar solvents respectively, whereas polar and non-polar substances are insoluble when mixed with each other. â¢ When a solute is soluble in a solvent they may make a homogenous mixture, but if they are insoluble they may not.