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Signs & Symptoms. ACTH deficiency can either be congenital or acquired, and its manifestations are clinically indistinguishable from those of glucocorticoid deficiency. Symptoms include weight loss, lack of appetite (anorexia), muscle weakness, nausea and vomiting, and low blood pressure (hypotension).
What do low TSH levels mean? According to About.com, low levels of TSH, or thyroid-stimulating hormone, occur when the pituitary gland shuts down TSH production due to high levels of thyroid hormone in the blood. The low levels of TSH are the pituitary gland's attempt to keep thyroid hormone levels normal within the body. What are some symptoms associated with high TSH levels? According to WebMD, high TSH (thyroid-stimulating hormone) levels indicate an underactive thyroid gland (hypothyroidism). Common symptoms include feeling weak, tired or depressed, sensitivity to cold, constipation, brittle nails, memory problems, and heavy or irregular periods.