As with other angiotensin II receptor antagonists, candesartan is indicated for the treatment of hypertension. Results from the CHARM study (early 2000s) demonstrated the morbidity and mortality reduction benefits of candesartan therapy in congestive heart failure.uring the first two years of the trial, half of participants were given candesartan, and the others received placebo; candesartan reduced the risk of developing hypertension by nearly two-thirds during this period. In the last two years of the study, all participants were switched to placebo.
Single-Instance Store and SIS Backup. Single-instance store, or SIS, is an architecture designed to maintain duplicate files with a minimum of disk, cache, and backup media overhead. Single-instance store backup, or SIS backup, is an API that backup applications call to access the SIS architecture. For more information, see the following topics:
Single Node or Psuedo-Distributed Cluster is the one in which all the essential daemons (like NameNode, DataNode, JobTracker and TaskTracker) run on the same machine. The default replication factor for a single node cluster is 1. A single node cluster is basically used to simulate a full cluster like environment and to test hadoop applications and unlike the Stand-alone mode, HDFS is accessible in this.