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Subchondral bone marrow edema is also commonly seen in patients with degenerative joint disease (10 â 14). Subchondral bone marrow edema in patients with osteoarthritis of the knee joint has been associated with knee pain and the progression of articular cartilage degeneration (12, 13).
A subchondral bone cyst is a fluid-filled sac that forms inside of and extends from the bone of a joint. It is seen on X-rays in cases of osteoarthritis. These cysts are not treated. They are a sign of osteoarthritis, although they do not occur in all cases.