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Ptosis is a condition that causes drooping eyelids. This could be caused by the weakening of muscles around the eye, aging, a complication of certain diseases, trauma, or it may be present from birth.
TSD is caused by inheriting a 'double-dose' of a fault in a gene which codes for the HexA enzyme. Every person has two copies of this gene in each cell of their body. A person will only be affected by TSD if s/he has a fault (mutation) in both copies of the HEXA gene.