Coitus interruptus, also known as the withdrawal. method, is the oldest form of male contraceptive. method to be practiced.[1] It involves the male partner. pulling out the penis before ejaculation.[1] Even though. it is the oldest method of male contraception to be. practiced, research has given it very little attention.
Updated September 18, 2016. Fermentation is an energy-yielding anaerobic metabolic process in which organisms convert nutrients (typically carbohydrates) to alcohols and acids (lactic acid and acetic acid). Fermentation is perhaps the most ancient biotechnological discovery.
In microorganisms, fermentation is the primary means of producing ATP by the degradation of organic nutrients anaerobically. Humans have used fermentation to produce drinks and beverages since the Neolithic age.