Medicines That Can Cause Tinnitus. Many prescription and nonprescription medicines can cause ringing in the ears (tinnitus). A few examples are: 1  Aspirin, ibuprofen (such as Advil or Motrin), and naproxen (such as Aleve). 2  Some blood pressure and heart medicines. 3  Some antidepressants.
Entrez Gene Summary for GULOP Gene. This gene is nonfunctional in humans and other primates. In most mammalian species the corresponding gene encodes L-gulono-gamma-lactone oxidase which catalyzes the last step of ascorbic acid biosynthesis.The human gene is a remnant that lacks five of twelve exons found in functional rodent genes.The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]. GULOP (Gulonolactone (L-) Oxidase, Pseudogene) is a Pseudogene.he human gene is a remnant that lacks five of twelve exons found in functional rodent genes. The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]. GULOP (Gulonolactone (L-) Oxidase, Pseudogene) is a Pseudogene.
TEXT. Cloning and Expression. Abbott et al. (1999) cloned and characterized KCNE2, a potassium channel gene encoding MinK-related peptide-1 (MiRP1), a small integral membrane subunit that assembles with the HERG gene product (KCNH2; 152427), a pore-forming protein, to alter its function.2006) identified biallelic digenic mutations: a 178C-T transition in exon 1 of the KCNE2 gene, resulting in a phe60-to-leu (F60L) substitution, and a missense mutation in the SCN5A gene (R1623Q; 600163.0007).