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It takes about 1 to 2 weeks to take effect. Also, when you are done with it, it takes about two weeks to get out of your system. Here is a detailed write-up about Celexa, which is Citalopram Hydrobromide. Citalopram Hydrobromide Monograph for Professionals - Drugs.com.
Best Answer: It can take anywhere from 2 to 3 months for your body to adjust....it also depends on your body size and the doage amount....if you feel real sluggish then contact your doctor he/she may need to adjust to a lower dosage.ow long does it usually take for your body to adjust to the medications Risperdal? I just began takingthis medication on Friday, along with Celexa, and i get very sleepy.