We know that certain environmental substances can trigger autoimmune disease. For example, silica can trigger scleroderma; certain drugs can trigger lupus; and, in some women, pregnancy can trigger an autoimmune disease. For more information: http://www.aarda.org/modules.php.
UPPER MOTOR NEURON DISORDERS (UMN). An upper motor neuron starts in the motor cortex of the brain and terminates within the medulla (another part of the brain) or within the spinal cord.So, an UMN disorder would include injury, disease or disturbance within this pathway from or within the brain and to the spinal cord (Photo 6).PPER MOTOR NEURON DISORDERS (UMN). An upper motor neuron starts in the motor cortex of the brain and terminates within the medulla (another part of the brain) or within the spinal cord.
Motor Neurone Disease (MND) is the name given to a group of closely related disorders affecting the motor neurones (nerve cells controlling muscles) in the brain and spinal cord. Degeneration of these motor neurones results in progressive muscle wasting and weakness because the muscles have lost their nerve supply.ecause MND is a progressive disease, the muscular weakness becomes worse with time. The patient may eventually require a wheelchair because of leg and trunk weakness, and become generally immobile. At some stage in the disease the patient will suffer from âbulbarâ symptoms.