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Live vaccines are sensitive to heat. MMRV, varicella, and zoster. vaccines must be stored in a continuously frozen state in a freezer at. 5Â°F (-15Â°C) or colder until administration. MMRV, varicella, and. Live vaccines are. sensitive to heat. zoster vaccines deteriorate rapidly after they are removed from the freezer.
The sterile. diluent does not contain preservatives or other anti-viral substances which might inactivate the vaccine. virus. Use a sterile syringe free of preservatives, antiseptics, and detergents for each reconstitution and. injection of VARIVAX because these substances may inactivate the vaccine virus. To reconstitute the vaccine, first withdraw the total volume of provided sterile diluent into a syringe.