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Subchondral bone marrow edema is also commonly seen in patients with degenerative joint disease (10 â 14). Subchondral bone marrow edema in patients with osteoarthritis of the knee joint has been associated with knee pain and the progression of articular cartilage degeneration (12, 13).
Bone marrow aspirates show predominantly megakaryocytic dysplasia with many small, hypolobated megakaryocytes (see the images below). Small, hypolobated megakaryocytes are typical of myelodysplastic syndrome with isolated del(5q) (bone marrow aspirate, Wright-Giemsa, Ã1000).