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Live vaccines are sensitive to heat. MMRV, varicella, and zoster. vaccines must be stored in a continuously frozen state in a freezer at. 5Â°F (-15Â°C) or colder until administration. MMRV, varicella, and. Live vaccines are. sensitive to heat. zoster vaccines deteriorate rapidly after they are removed from the freezer.
Varicella-containing vaccines may be transported at refrigerator temperature between 36Â°F and 46Â°F (2Â°C and 8Â°C) for up to 72 continuous hours prior to reconstitution. Vaccine stored between 36Â°F and 46Â°F (2Â°C and 8Â°C) that is not used within 72 hours of removal from a freezer should be discarded.