Dremel 543 and EZ544 are both carbide cutting wheels for cutting and shaping on woods, fiberglass, plastics and laminates. Do not use them on metals. For 543 the mandrel is included; for EZ544 use the EZ402 Mandrel.
After Domagk published his findings in 1935, doctors found that Prontosil could control many bacterial infections. Subsequently, other researchers developed derivatives based on the Prontosil sulfonamide group. The resulting so-called sulfa drugs revolutionized medicine and saved many thousands of lives.
Sulfa allergy is a term used to describe adverse drug reactions to sulfonamides, a group of drugs that includes those with and without antibiotic characteristics. Antibiotic sulfonamides were the first antibiotics used to treat infections, although today are used much less frequently given their common side effects.