Dremel 543 and EZ544 are both carbide cutting wheels for cutting and shaping on woods, fiberglass, plastics and laminates. Do not use them on metals. For 543 the mandrel is included; for EZ544 use the EZ402 Mandrel.
After Domagk published his findings in 1935, doctors found that Prontosil could control many bacterial infections. Subsequently, other researchers developed derivatives based on the Prontosil sulfonamide group. The resulting so-called sulfa drugs revolutionized medicine and saved many thousands of lives.
Salbutamol was the first selective Î² 2 -receptor agonist to be marketed in 1968. It was first sold by Allen & Hanburys (UK) under the brand name Ventolin, and has been used for the treatment of asthma ever since. It was approved for use in the US by the Food and Drug Administration (FDA) in May 1982. The drug is usually manufactured and distributed as the sulfate salt salbutamol sulfate. Salbutamol is mostly taken by the inhaled route for direct effect on bronchial smooth muscle.