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Ptosis is a condition that causes drooping eyelids. This could be caused by the weakening of muscles around the eye, aging, a complication of certain diseases, trauma, or it may be present from birth.
Like Patau syndrome, Down syndrome is caused by having an extra copy of a certain chromosome. Individuals with Down syndrome usually have an extra copy of chromosome 21. Thus, Down syndrome is commonly called trisomy 21. Perhaps not surprisingly, the cause of the trisomy in both Patau and Down syndromes is similar. A phenomenon called nondisjunction is responsible for most cases of trisomy 13 and 21.