An inverse agonist vs antagonist. An antagonist reduces the effect of an agonist by preventing it from binding to receptors. Both antagonists and inverse agonists reduce the activity if a receptor and, in the presence of an agonist, reduce its activity.n antagonist reduces the effect of an agonist by preventing it from binding to receptors. Both antagonists and inverse agonists reduce the activity if a receptor and, in the presence of an agonist, reduce its activity.
The 249 episodes followed Sheriff Andy Taylor (Griffith), his bumbling deputy Barney Fife (Don Knotts), son Opie (Ronnie Howard) and the lovable Aunt Bea (Frances Bavier). Here are a few fun facts you might not know about this TV classic:
Extended family. 1  Gladys Gurney, voiced by Julie Kavner, is Marge's spinster aunt and the sister of Jacqueline. Her death was noted in the episode Selma's Choice, in which she died of a bowel obstruction. 2  Great Uncle Hubert is Bart, Lisa, and Maggie's great uncle who died in the short The Funeral.