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By comparison, people with Parkinsonâs disease typically experience a hand tremor when their muscles are at rest and see a reduction in the tremor when their muscles are in use. Shaky hands can also be caused by: 1  seizure. 2  overactive thyroid. 3  cerebellar disease. 4  Huntingtonâs disease.
Immune System Disorders. Schleroderma and psoriasis are two of the many autoimmune disorders that can cause skin peeling on fingers and hands. These conditions are only some of the possible medical conditions that can cause this symptom. A condition called Kawasaki disease can also cause skin to peel on the hands. This condition most commonly affects only children age five and younger. Fungal infections and allergic reactions are common causes of skin that itches and peels.