Medicines That Can Cause Tinnitus. Many prescription and nonprescription medicines can cause ringing in the ears (tinnitus). A few examples are: 1  Aspirin, ibuprofen (such as Advil or Motrin), and naproxen (such as Aleve). 2  Some blood pressure and heart medicines. 3  Some antidepressants.
Entrez Gene Summary for GULOP Gene. This gene is nonfunctional in humans and other primates. In most mammalian species the corresponding gene encodes L-gulono-gamma-lactone oxidase which catalyzes the last step of ascorbic acid biosynthesis.The human gene is a remnant that lacks five of twelve exons found in functional rodent genes.The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]. GULOP (Gulonolactone (L-) Oxidase, Pseudogene) is a Pseudogene.he human gene is a remnant that lacks five of twelve exons found in functional rodent genes. The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]. GULOP (Gulonolactone (L-) Oxidase, Pseudogene) is a Pseudogene.
Another important aspect of consideration for the GULO gene degradation found in humans is the fact that it occurs frequently in mammals and birds, and the events typically are associated with complete or partial loss of exons. This indicates that the gene may be predisposed to the effects of genetic entropy.his wealth of data has revealed wide-spread genetic entropy in human and other genomes. Loss of the vitamin C pathway due to deletions in the GULO (L-gulonolactone oxidase) gene has been detected in humans, apes, guinea pigs, bats, mice, rats, pigs, and passerine birds.