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The main function of nucleolus is to produce and assemble subunits which form the ribosome. Ribosome is the site for protein synthesis. Nucleolus plays an indirect but crucial role in protein synthesis by assembling the ribosome subunits.he chains of RNA and DNA are the structural components of nucleolus. It is composed of granular and fibrillar components. The fibrillar components are categorized into fibrillar centers and dense fibrillar component. This type of structural organization of nucleolus is found in eukaryotic cells.
Confidence votes 15. nucleoli form ribosomes. The ribosomes are known to produce or manufacture proteins and therefore, nucleolus plays an indirect role in protein synthesis. Out of the total production of RNA that takes place in the cells, nucleolus is involved in 50% of the RNA synthesis.This functionality of nucleolus is attributed to hundreds of r-genes.he ribosomes are known to produce or manufacture proteins and therefore, nucleolus plays an indirect role in protein synthesis. Out of the total production of RNA that takes place in the cells, nucleolus is involved in 50% of the RNA synthesis.