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Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is not known. Degenerative nerve diseases include. 1  Alzheimer's disease. 2  Amyotrophic lateral sclerosis.
Neurodegenerative Diseases Program Description. Neurodegenerative diseases affect millions of people worldwide, and Alzheimerâs disease and Parkinsonâs disease are the most common types. More than five million Americans are living with Alzheimerâs disease, and at least 500,000 Americans live with Parkinson's disease, although some estimates are much higher.