An inverse agonist vs antagonist. An antagonist reduces the effect of an agonist by preventing it from binding to receptors. Both antagonists and inverse agonists reduce the activity if a receptor and, in the presence of an agonist, reduce its activity.n antagonist reduces the effect of an agonist by preventing it from binding to receptors. Both antagonists and inverse agonists reduce the activity if a receptor and, in the presence of an agonist, reduce its activity.
The 249 episodes followed Sheriff Andy Taylor (Griffith), his bumbling deputy Barney Fife (Don Knotts), son Opie (Ronnie Howard) and the lovable Aunt Bea (Frances Bavier). Here are a few fun facts you might not know about this TV classic:
Most prominent among them is Ron Howard, who played Andy's son Opie and is now one of the most successful film directors in Hollywood. Howard began directing short films soon after the end of The Andy Griffith Show in 1968 and had already achieved box-office success by the time Return to Mayberry was filmed in 1986.etty Lynn, who played Barney's girlfriend Thelma Lou, currently lives in Mount Airy, N.C. It was Andy Griffith's birthplace and widely believed to be the inspiration for Mayberry. She makes monthly appearances on the town's Andy Griffith Museum on the third Friday of the month.