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He said that results of this study suggest that there may be two separate ways the brain communicates with the spleen to regulate immune function. This points the way to a possible solution for treating sepsis. It may be more effective to take advantage of the central nervous system to control cells of the spleen.
The Enteric Endocrine System. The second of the two systems that control digestive function is the endocrine system, which regulates function by secreting hormones. Recall that hormones are chemical messengers secreted into blood that modify the physiology of target cells.