The adjectives adverse and averse are related both etymologically and semantically, each having âoppositionâ as a central sense. Adverse is seldom used of people but rather of effects or events, and it usually conveys a sense of hostility or harmfulness: adverse reviews; adverse winds; adverse trends in the economy. Related nouns are adversity and adversary: Adversities breed bitterness. His adversaries countered his every move.
After oral administration, there is an early rise in serum concentration. Equilibration of serum and tissue levels occurs at approximately 6 to 8 hours. For this reason, blood specimens for digoxin analysis should be drawn at least 6 to 8 hours after drug administration. Digoxin is excreted primarily in the urine.
Tamoxifen is prescribed as a pill you take once a day by mouth. For breast cancer risk reduction, tamoxifen is typically taken for a total of five years. The risk reduction benefit continues for five additional years after you stop taking tamoxifen, so in total, women receive up to 10 years of benefit.