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Yikes! A slice of cheddar cheese clocks in at 174 milligrams of sodium, while a slice of American has 351 milligrams. Neither will break the sodium bank, but keep in mind that's just one slice. Some cheeses are naturally much lower in sodium, like Parmesan, which contains just 76 milligrams of sodium per grated tablespoon.
Sodium is found in massive abundance in macaroni and cheese, a fact that might concern you because of the harmful effects that sodium is tied to. From one helping of macaroni and cheese, which works out to around 418 grams, you are exposing yourself to a distressingly high amount of 1760 milligrams of sodium.