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â High blood pressure: it is also one kidney shrinkage symptoms. â Hematuria: when patients are suffering from some infections such as urinary tract infections, hematuria will occur. The kidney shrinkage causes and symptoms are able to help patients get correct treatment.
1 A severe decrease in kidney function can lead to a buildup of toxins and impurities in the blood. This can cause people to feel tired, weak and can make it hard to concentrate. Another complication of kidney disease is anemia, which can cause weakness and fatigue.  You're having trouble sleeping.