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Live vaccines are sensitive to heat. MMRV, varicella, and zoster. vaccines must be stored in a continuously frozen state in a freezer at. 5Â°F (-15Â°C) or colder until administration. MMRV, varicella, and. Live vaccines are. sensitive to heat. zoster vaccines deteriorate rapidly after they are removed from the freezer.
Mishaps in Vaccine Storage or Handling. 1  Do not assume the vaccine cannot be salvaged. 2  Record the temperature inside the refrigerator at the time the problem is discovered. 3  Transfer the vaccine to a working refrigerator as quickly as possible. 4  Record the length of time the vaccine may have been exposed to non-optimal temperatures.