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By comparison, people with Parkinsonâs disease typically experience a hand tremor when their muscles are at rest and see a reduction in the tremor when their muscles are in use. Shaky hands can also be caused by: 1  seizure. 2  overactive thyroid. 3  cerebellar disease. 4  Huntingtonâs disease.
How are Raynaud's and other diseases associated with cold hands syndrome? There are several conditions that can cause cold hands syndrome, including autoimmune, connective tissue and vascular diseases. Characterized by decreased blood flow to the extremities, Raynaud's is one of the most common examples.