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Signs & Symptoms. ACTH deficiency can either be congenital or acquired, and its manifestations are clinically indistinguishable from those of glucocorticoid deficiency. Symptoms include weight loss, lack of appetite (anorexia), muscle weakness, nausea and vomiting, and low blood pressure (hypotension).
Low TSH Levels. Low TSH levels can indicate hyperthyroidism, TSH deficiency or the result of certain medications. Symptoms of an overactive thyroid include nervousness, irritability, increased perspiration, heart racing, hand tremors, anxiety, diarrhea, vision changes and muscle weakness.ow TSH levels can indicate hyperthyroidism, TSH deficiency or the result of certain medications. Symptoms of an overactive thyroid include nervousness, irritability, increased perspiration, heart racing, hand tremors, anxiety, diarrhea, vision changes and muscle weakness.