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An acute exacerbation of COPD is defined as increased shortness of breath, increased sputum production, a change in the color of the sputum from clear to green or yellow, or an increase in cough in someone with COPD.
Of the articles identified by our search, 7 described the costs associated with hospitalizations for acute exacerbations of COPD in the United States. For example, Wier and colleagues analyzed data from the Healthcare Cost and Utilization Project for patients aged â¥40 years who were hospitalized with COPD in 2008.