As with other angiotensin II receptor antagonists, candesartan is indicated for the treatment of hypertension. Results from the CHARM study (early 2000s) demonstrated the morbidity and mortality reduction benefits of candesartan therapy in congestive heart failure.uring the first two years of the trial, half of participants were given candesartan, and the others received placebo; candesartan reduced the risk of developing hypertension by nearly two-thirds during this period. In the last two years of the study, all participants were switched to placebo.
Single Instance Storage. The Single Instance Storage (SIS) feature reduces the amount of space that is used to store data on a volume. SIS does this by replacing duplicate files with logical links that point to a single copy of the file in the SIS Common Store, which is a hidden folder that is located in the root directory of the volume.
Network-attached storage (NAS) was designed before the emergence of SAN as a solution to the limitations of the traditionally used direct-attached storage (DAS), in which individual storage devices such as disk drives are connected directly to each individual computer and not shared.ne drawback to both the NAS and SAN architecture is that the connection between the various CPUs and the storage units are no longer dedicated high-speed busses tailored to the needs of storage access. Instead the CPUs use the LAN to communicate, potentially creating bandwidth bottlenecks.