We know that certain environmental substances can trigger autoimmune disease. For example, silica can trigger scleroderma; certain drugs can trigger lupus; and, in some women, pregnancy can trigger an autoimmune disease. For more information: http://www.aarda.org/modules.php.
UPPER MOTOR NEURON DISORDERS (UMN). An upper motor neuron starts in the motor cortex of the brain and terminates within the medulla (another part of the brain) or within the spinal cord.So, an UMN disorder would include injury, disease or disturbance within this pathway from or within the brain and to the spinal cord (Photo 6).PPER MOTOR NEURON DISORDERS (UMN). An upper motor neuron starts in the motor cortex of the brain and terminates within the medulla (another part of the brain) or within the spinal cord.
Multifocal motor neuropathy (MMN) is a progressively worsening condition where muscles in the extremities gradually weaken. The disorder, a pure motor neuropathy syndrome, is sometimes mistaken for amyotrophic lateral sclerosis (ALS) because of the similarity in the clinical picture, especially if muscle fasciculations are present. MMN is thought to be autoimmune. It was first described in the mid-1980s.