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Subchondral bone marrow edema is also commonly seen in patients with degenerative joint disease (10 â 14). Subchondral bone marrow edema in patients with osteoarthritis of the knee joint has been associated with knee pain and the progression of articular cartilage degeneration (12, 13).
Updated April 15, 2017. Subchondral sclerosis is a painful condition that affects people who have osteoarthritis. Fortunately, itâs easily detected and there are several treatment options available. To understand what subchondral sclerosis is, itâs useful to have a clear picture of how osteoarthritis affects the joints of the body. Not only does osteoarthritis degrade the cartilage in a joint, it also wears away at the subchondral bone underneath the cartilage.