Complications of Uncontrolled, Persistent Pain. Persistent, unremitting pain may adversely affect the bodyâs endocrine, cardiovascular, immune, neurologic and musculo-skeletal systems and require aggressive treatment of the pain as well as the resulting complications. By Forest Tennant, MD, DrPH.
The noun PREFECTURE has 2 senses: 1. the district administered by a prefect (as in France or Japan or the Roman Empire) 2. the office of prefect. Familiarity information: PREFECTURE used as a noun is rare.
metropolitan. 1  of or constituting a metropolis (senses 2  &). designating or of a metropolitan 3  (). â designating or of a population area consisting of a central city and smaller surrounding communities. 4  designating or of a mother country as distinguished from a colony, territory, etc.