Complications of Uncontrolled, Persistent Pain. Persistent, unremitting pain may adversely affect the bodyâs endocrine, cardiovascular, immune, neurologic and musculo-skeletal systems and require aggressive treatment of the pain as well as the resulting complications. By Forest Tennant, MD, DrPH.
The noun PREFECTURE has 2 senses: 1. the district administered by a prefect (as in France or Japan or the Roman Empire) 2. the office of prefect. Familiarity information: PREFECTURE used as a noun is rare.
The West's use of prefecture to label these Japanese regions stems from 16th-century Portuguese explorers' and traders' use of  prefeitura  to describe the fiefdoms they encountered there. Its original sense in Portuguese, however, was closer to  municipality  than  province .