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Definition. 1  Cardiomyopathy is a chronic disease of the heart muscle (myocardium), in which the muscle is abnormally enlarged, thickened, and/or stiffened. The weakened heart muscle loses the ability to pump blood effectively, resulting in irregular heartbeats (arrhythmias) and possibly even heart failure.
Dilated Cardiomyopathy Definition. A disorder in which the chambers of the heart are dilated (enlarged) because the heart muscle is weakened and cannot pump effectively. There are many causes, the most common being myocardial ischemia (not enough oxygen supplied to the heart muscle) due to coronary artery disease.