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A low RBC count indicates a decrease in oxygen-carrying cells in blood. The causes can be many, ranging from infections and deficiencies to malnutrition to malignancies, including: Anemia
A: A low hematocrit level may mean the patient is malnourished, anemic, overhydrated or bleeding, according to MedlinePlus. A low hematocrit level may also be due to nutritional deficiencies, leukemia or the destruction of red blood cells.