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Though Zofran was originally created in 1984 to treat nausea and vomiting in cancer patients after receiving chemotherapy, the drug is most commonly used today by pregnant women. It metabolizes in the liver and has a shelf-life of five to seven hours. Common side effects of the drug are headaches and sometimes constipation.
Zofran is a brand name for the drug ondansetron, prescribed to treat or prevent nausea and vomiting. Doctors sometimes prescribe Zofran to treat nausea and vomiting caused by cancer treatments such as chemotherapy and radiation therapy. Zofran also can treat nausea and vomiting after surgery.