The adjectives adverse and averse are related both etymologically and semantically, each having âoppositionâ as a central sense. Adverse is seldom used of people but rather of effects or events, and it usually conveys a sense of hostility or harmfulness: adverse reviews; adverse winds; adverse trends in the economy. Related nouns are adversity and adversary: Adversities breed bitterness. His adversaries countered his every move.
After oral administration, there is an early rise in serum concentration. Equilibration of serum and tissue levels occurs at approximately 6 to 8 hours. For this reason, blood specimens for digoxin analysis should be drawn at least 6 to 8 hours after drug administration. Digoxin is excreted primarily in the urine.
TSH above upper limit of normal and low FT 4 (clinical hypothyroidism): Start levothyroxine (SynthroidÂ®) at 0.075 mg to 0.125 mg once a day for all patients under age 60 and no known coronary artery disease (CAD).echeck TSH and FT 4 in 6 weeks and adjust as necessary every 6 weeks until TSH is between 1.0 and 3.0 uIU/ml. If patient is over age 60 years of age and / or has known CAD, start with 0.025 mg and adjust every 6 weeks.