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Live vaccines are sensitive to heat. MMRV, varicella, and zoster. vaccines must be stored in a continuously frozen state in a freezer at. 5Â°F (-15Â°C) or colder until administration. MMRV, varicella, and. Live vaccines are. sensitive to heat. zoster vaccines deteriorate rapidly after they are removed from the freezer.
Compared with use of MMR and varicella vaccines at the same visit, use of MMRV vaccine is associated with a higher risk for fever and febrile seizures 5â12 days after the first dose among children aged 12â23 months and approximately 1 additional febrile seizure for every 2,300â2,600 MMRV vaccine doses administered.ompared with use of MMR and varicella vaccines at the same visit, use of MMRV vaccine is associated with a higher risk for fever and febrile seizures 5â12 days after the first dose among children aged 12â23 months and approximately 1 additional febrile seizure for every 2,300â2,600 MMRV vaccine doses administered.