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The general rule of thumb for Benadryl dosage for dogs is 1mg per 1lb of the dogâs weight. Itâs generally safe to give your puppy the medicine 2-3 times/day.
Yes 1mg per pound with the dog, but this goes for pill version not liquid. Liquid has to go by the density of the liquid you are giving. I have a 55lb dog and liquid benadryl would be no more than 1/4tsp MAX for this size, and that's almost too much. The above is not accurate..