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Subchondral bone marrow edema is also commonly seen in patients with degenerative joint disease (10 â 14). Subchondral bone marrow edema in patients with osteoarthritis of the knee joint has been associated with knee pain and the progression of articular cartilage degeneration (12, 13).
External signs of subchondral sclerosis. Subchondral sclerosis can be detected with radiology, i.e. it's visible in X-rays of the joints and is the result of a reactive bone response, resulting in increased bone density of the underlying articular cartilage bone (that's underneath the joint).reatment for subchondral sclerosis can be varied depending on the affected area and intensity of the disease. Below we list some treatment options, but remember to always consult a specialist who will prescribe the appropriate treatment: 1  Physical exercises such as swimming and using a stationary bicycle.