Dremel 543 and EZ544 are both carbide cutting wheels for cutting and shaping on woods, fiberglass, plastics and laminates. Do not use them on metals. For 543 the mandrel is included; for EZ544 use the EZ402 Mandrel.
After Domagk published his findings in 1935, doctors found that Prontosil could control many bacterial infections. Subsequently, other researchers developed derivatives based on the Prontosil sulfonamide group. The resulting so-called sulfa drugs revolutionized medicine and saved many thousands of lives.
It is important to make a distinction between sulfa drugs and other sulfur-containing drugs and additives, such as sulfates and sulfites, which are chemically unrelated to the sulfonamide group, and do not cause the same hypersensitivity reactions seen in the sulfonamides.t is important to make a distinction between sulfa drugs and other sulfur-containing drugs and additives, such as sulfates and sulfites, which are chemically unrelated to the sulfonamide group, and do not cause the same hypersensitivity reactions seen in the sulfonamides.