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By comparison, people with Parkinsonâs disease typically experience a hand tremor when their muscles are at rest and see a reduction in the tremor when their muscles are in use. Shaky hands can also be caused by: 1  seizure. 2  overactive thyroid. 3  cerebellar disease. 4  Huntingtonâs disease.
Medications or Substances causing Hand tremors. Medications or substances causing Hand tremors. The following drugs, medications, substances or toxins are some of the possible causes of Hand tremors as a symptom. This list is incomplete and various other drugs or substances may cause your symptoms (see Hand tremors). Always advise your doctor of any medications or treatments you are using, including prescription, over-the-counter, supplements, herbal or alternative treatments.