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Allergic causes of peeling skin. Drug, animal, food, and other environmental allergens can lead to peeling skin including: Atopic dermatitis (eczema) Contact dermatitis (contact with allergens, such as perfumes, poison ivy, and soaps)
What Causes Peeling Palms. 1  The peeling of palms is associated with several symptoms including dryness, redness, rashes, burning sensation, pain, and itchiness. There are many reasons why the palmar skin peels off, and a few of these are disorders such as: 2  Exfoliative keratolysis. Also called focal palm peeling, the exfoliative keratolysis is a condition of severe peeling of palmar skin, preceded by an outburst of air-filled blisters throughout the palms and fingers. The blisters, which may be caused by eczema, also cause the palm to peel off. Hand dermatitis.