Spend 60-70% of your time cycling (i.e. for every 10 hours training cycle 7 hours run 2 hours and swim 1 hour) This is only a very basic guide line for injury prevention and you will get some cross over in fitness, the better you are on a bike your ironman marathon will be easier to complete.
People with liver disease and high alcohol intake may be at risk for liver toxicity from vitamin A supplementation. Vitamin A toxicity may lead to intrahepatic cholestasis, where bile cannot flow from the liver into the intestines. Vitamin A may cause low blood pressure. Caution is advised in people with low blood pressure or in those taking drugs or herbs and supplements that lower blood pressure.
But not all vitamins are water-soluble, and the ones that are lipid-soluble, meaning they like to hang around in your body's fat, don't get flushed out. Instead, if you take too much of a lipid-soluble vitamin over a few weeks to a month, they sit in the liver and can build up to toxic levels, causing problems ranging from weak bones to liver damage, according to Katherine Zeratsky, a registered dietician nutritionist at the Mayo Clinic.