If the force is a point load it is simply the force x the distance [1] If the force is distributed or spread out you must integrate the forces and the distances [2]. Shear force is a function of the total force and the cross sectional area [2].
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Interstitial Cystitis Causes. An unexplained association of IC has been found to exist with other autoimmune diseases such as inflammatory bowel disease, systemic lupus erythematosus, scleroderma, Sjogren syndrome, fibromyalgia, and atopic allergy.