Medicines That Can Cause Tinnitus. Many prescription and nonprescription medicines can cause ringing in the ears (tinnitus). A few examples are: 1  Aspirin, ibuprofen (such as Advil or Motrin), and naproxen (such as Aleve). 2  Some blood pressure and heart medicines. 3  Some antidepressants.
Entrez Gene Summary for GULOP Gene. This gene is nonfunctional in humans and other primates. In most mammalian species the corresponding gene encodes L-gulono-gamma-lactone oxidase which catalyzes the last step of ascorbic acid biosynthesis.The human gene is a remnant that lacks five of twelve exons found in functional rodent genes.The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]. GULOP (Gulonolactone (L-) Oxidase, Pseudogene) is a Pseudogene.he human gene is a remnant that lacks five of twelve exons found in functional rodent genes. The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]. GULOP (Gulonolactone (L-) Oxidase, Pseudogene) is a Pseudogene.
Pilot gene expression profiling studies in patients with CLL identified genes that were differentially expressed between the Ig-unmutated and Ig-mutated CLL subtypes. Here, we have profiled an expanded cohort of 107 patients and show that ZAP-70 is the gene that best distinguishes the CLL subtypes.Ig-unmutated CLL expressed ZAP-70 5.54-fold more highly than Ig-mutated CLL (P -21). ZAP-70 expression correctly predicted IgVH mutation status in 93% of patients.ere, we have profiled an expanded cohort of 107 patients and show that ZAP-70 is the gene that best distinguishes the CLL subtypes. Ig-unmutated CLL expressed ZAP-70 5.54-fold more highly than Ig-mutated CLL (P -21). ZAP-70 expression correctly predicted IgVH mutation status in 93% of patients.