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Chickenpox, also known as varicella, is a highly contagious disease caused by the initial infection with varicella zoster virus (VZV).The disease results in a characteristic skin rash that forms small, itchy blisters, which eventually scab over.hickenpox, also known as varicella, is a highly contagious disease caused by the initial infection with varicella zoster virus (VZV).
A pox is a type of disease, often caused by an animal virus, characterised by pockmarks. The term may be used (in an archaic sense) to refer to disease. Pox, as a disease, may refer to: 1  Poxviruses.  Cowpox.