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Ptosis is a condition that causes drooping eyelids. This could be caused by the weakening of muscles around the eye, aging, a complication of certain diseases, trauma, or it may be present from birth.
Down syndrome is typically caused by what is called nondisjunction. Nondisjunction happens when a pair of chromosomes fails to separate during egg (or sperm) formation. When that egg unites with a normal sperm to form an embryo, the embryo ends up with three copies of chromosome 21 instead of the normal two.