Complications of Uncontrolled, Persistent Pain. Persistent, unremitting pain may adversely affect the bodyâs endocrine, cardiovascular, immune, neurologic and musculo-skeletal systems and require aggressive treatment of the pain as well as the resulting complications. By Forest Tennant, MD, DrPH.
The noun PREFECTURE has 2 senses: 1. the district administered by a prefect (as in France or Japan or the Roman Empire) 2. the office of prefect. Familiarity information: PREFECTURE used as a noun is rare.
metropolis. 1  the main city, often the capital, of a country, state, or region. 2  any large city or center of population, culture, etc. 3  in ancient Greece, the mother city or state of a colony.