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Subchondral bone marrow edema is also commonly seen in patients with degenerative joint disease (10 â 14). Subchondral bone marrow edema in patients with osteoarthritis of the knee joint has been associated with knee pain and the progression of articular cartilage degeneration (12, 13).
Vasogenic edema is due to compromise of the blood-brain barrier by damaged capillaries that allow plasma leakage into brain tissue. Ischemic edema is due to a combination of cytotoxic and vasogenic processes. Cerebral edema is the major cause of reduced blood flow to the brain.