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The main enzymes involved in DNA replication are: Helicase: unwinds the double helix into two strands Polymerase: adds nucleotides to an existing strand Ligase: brings togeth â¦ er the Okazaki fragments Topoisomerase: cuts and rejoins the helix RNA primase: catalyzes the synthesis of RNA primers Hope this helps!
na helicase and dna polermerases dna helicase-an enzyme that unwinds teh dna double helix during dna replication dna polymerase-an enzyme that catalyzes the formation of the dna molecule.a helicase and dna polermerases dna helicase-an enzyme that unwinds teh dna double helix during dna replication dna polymerase-an enzyme that catalyzes the formation of the dna molecule.