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Definition. 1  Cardiomyopathy is a chronic disease of the heart muscle (myocardium), in which the muscle is abnormally enlarged, thickened, and/or stiffened. The weakened heart muscle loses the ability to pump blood effectively, resulting in irregular heartbeats (arrhythmias) and possibly even heart failure.
Learn about the types, symptoms, treatment, and prognosis of this disease. Cardiomyopathy is a progressive disease of the myocardium, or heart muscle. In most cases, the heart muscle becomes weakened and unable to pump blood to the rest of the body as well as it should.ilated. The most common form, dilated cardiomyopathy (DCM) occurs when the heart muscle becomes too weak to pump blood effectively. The muscles stretch and become thinner, allowing the chambers of the heart to expand or âdilate.â.