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It takes about 1 to 2 weeks to take effect. Also, when you are done with it, it takes about two weeks to get out of your system. Here is a detailed write-up about Celexa, which is Citalopram Hydrobromide. Citalopram Hydrobromide Monograph for Professionals - Drugs.com.
It is not entirely clear why the medication causes weight loss. Celexa can often cause loss of appetite, nausea, and diarrhea, which may contribute to this. Often, these side effects go away with time. Also, since weight gain can be a depression symptom, treating the depression can lead to weight loss.t is unclear why Celexa causes this, but factors such as loss of appetite, nausea, and diarrhea (all potential side effects) may contribute to the unintended weight loss.