An inverse agonist vs antagonist. An antagonist reduces the effect of an agonist by preventing it from binding to receptors. Both antagonists and inverse agonists reduce the activity if a receptor and, in the presence of an agonist, reduce its activity.n antagonist reduces the effect of an agonist by preventing it from binding to receptors. Both antagonists and inverse agonists reduce the activity if a receptor and, in the presence of an agonist, reduce its activity.
The 249 episodes followed Sheriff Andy Taylor (Griffith), his bumbling deputy Barney Fife (Don Knotts), son Opie (Ronnie Howard) and the lovable Aunt Bea (Frances Bavier). Here are a few fun facts you might not know about this TV classic:
Betty Lynn, who played Barney's girlfriend Thelma Lou, currently lives in Mount Airy, N.C. It was Andy Griffith's birthplace and widely believed to be the inspiration for Mayberry. She makes monthly appearances on the town's Andy Griffith Museum on the third Friday of the month. Elinor Donahue, who played the town pharmacist and Andy's girlfriend in the show's first season, continues to work occasionally.