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Subchondral bone marrow edema is also commonly seen in patients with degenerative joint disease (10 â 14). Subchondral bone marrow edema in patients with osteoarthritis of the knee joint has been associated with knee pain and the progression of articular cartilage degeneration (12, 13).
Edema per se is not a major constituent of histologic abnormalities in the bone marrow in the majority of cases. It may be the only finding on MRI. Bone marrow edema is reversible in cases of bone bruise and algodystrophy, but it indicates a poor prognosis in osteoarthritis.