Coitus interruptus, also known as the withdrawal. method, is the oldest form of male contraceptive. method to be practiced.[1] It involves the male partner. pulling out the penis before ejaculation.[1] Even though. it is the oldest method of male contraception to be. practiced, research has given it very little attention.
Updated September 18, 2016. Fermentation is an energy-yielding anaerobic metabolic process in which organisms convert nutrients (typically carbohydrates) to alcohols and acids (lactic acid and acetic acid). Fermentation is perhaps the most ancient biotechnological discovery.
Evolution of aerobic fermentation. Aerobic fermentation is a metabolic process by which cells metabolize sugars via fermentation in the presence of oxygen and occurs through the repression of normal respiratory metabolism (also referred to as the crabtree effect in yeast).