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By comparison, people with Parkinsonâs disease typically experience a hand tremor when their muscles are at rest and see a reduction in the tremor when their muscles are in use. Shaky hands can also be caused by: 1  seizure. 2  overactive thyroid. 3  cerebellar disease. 4  Huntingtonâs disease.
Causes of Cold Hands. Anemia Anemia is the condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin...learn more Â». Diabetes (Type 1 and Type 2) Diabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood.