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A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells. The spliceosome is assembled from snRNAs and protein complexes. The spliceosome removes introns from a transcribed pre-mRNA, a kind of primary transcript.This process is generally referred to as splicing.he RNA component of the small nuclear ribonucleic protein or snRNP (pronounced snurp) is rich in uridine (the nucleoside analog of the uracil nucleotide). The canonical assembly of the spliceosome occurs anew on each hnRNA (pre-mRNA).
Interspersed within the exons are introns, regions of non-coding DNA. Introns must be removed from the initial transcript of mRNA before the final mature transcript is sent to the ribosome for translation into protein. This removal is done in a coimplex protein structure called the spliceosome.The spliceosome splices out the non-coding introns from the primary mRNA transcript, and stiches the exons back together into the mature mRNA transcript.he spliceosome is a complex of small nuclear RNA (snRNA) and small nuclear protein (snRNP) molecules, snRNAs and snRNPs.