There are 4 tablespoons in a quarter cup and there are 3 teaspoons in each tablespoon; this means that there are 12 teaspoons in a quarter cup. A quarter cup is also equal to 2 fluid ounces.
In brief: Yes. Opiods have a slowing effect on gastomotility commonly causing side effects like constipation and nausea. Abrupt withdrawal of opioids from the system can cause rebound hypermotility of the GI tract which usually presents as diarrhea as well as GI spasm or craming causing abdominal pain (stomach pain).
Perhaps the most common set of side effects for drugs taken internally involves the gastrointestinal system. Nearly any drug can cause nausea or an upset stomach, though it may only happen to a handful of users. For drugs used externally, skin irritation is a common complaint.