Where, as above, C is annuity payment, PV is principal, n is number of payments, starting at end of first period, and i is interest rate per period. Equivalently C is the periodic loan repayment for a loan of PV extending over n periods at interest rate, i.
Refractory epilepsy is a seizure disorder that resists drug treatment. There is some debate among clinicians and researchers about how to define refractory epilepsy. As a result, this term is used in a variety of ways, and when a patient's epilepsy is described as refractory, resistant, or nonresponsive, it can be advisable to ask for more detail about what the diagnosis means.
â¢ REFRACTORY (noun) The noun REFRACTORY has 1 sense: 1. lining consisting of material with a high melting point; used to line the inside walls of a furnace. Familiarity information: REFRACTORY used as a noun is very rare. â¢ REFRACTORY (adjective) The adjective REFRACTORY has 3 senses: 1. not responding to treatment 2. temporarily unresponsive or not fully responsive to nervous or sexual stimuli 3. stubbornly resistant to authority or control Familiarity information: REFRACTORY used as an adjective is uncommon.