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Symptoms. Usually there are no symptoms. If the protein loss is heavy, the urine has a frothy appearance, and would most likely be associated with other symptoms e.g. oedema, where there is an excess of water in the body tissues. Possible causes of proteinuria
Risk Factors for Proteinuria. Both diabetes and high blood pressure can cause damage to the kidneys, which leads to proteinuria. Other types of kidney disease unrelated to diabetes or high blood pressure can also cause protein to leak into the urine. Increased production of proteins in the body can lead to proteinuria.