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The general rule of thumb for Benadryl dosage for dogs is 1mg per 1lb of the dogâs weight. Itâs generally safe to give your puppy the medicine 2-3 times/day.
Diphenhydramine (the active ingredient in Benadryl) is also a component of the recreational Diphenhydramine generally has a low abuse profile due to the frequently A safe amount is around 12-14 25mg tablets which is equal to around can an adult take. 30ml. How much benadryl is safe to take per day.ore: http://www.chacha.com/question/how-often-can-you-take-benadryl-allergy-ultratab-25mg-tablet. Reply. says: April 6, 2012 at 11:53 am. My vet has advised 1 mg of benadryl for each pound your dog weighs. So, one 25 mg pill should be enough.