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Integrin. Definition. noun, plural: integrins. A large group of cell adhesion molecule comprised of two subunits (ï¡- and ï¢- subunits) that are both essential in promoting cell adhesion (i.e. cell binding to another cell or to an extracellular matrix component).ntegrin. Definition. noun, plural: integrins. A large group of cell adhesion molecule comprised of two subunits (ï¡- and ï¢- subunits) that are both essential in promoting cell adhesion (i.e. cell binding to another cell or to an extracellular matrix component).
The molecular mass of the integrin subunits can vary from 90 kDa to 160 kDa. Beta subunits have four cysteine-rich repeated sequences. Both Î± and Î² subunits bind several divalent cations. The role of divalent cations in the Î± subunit is unknown, but may stabilize the folds of the protein.here are several types of integrins, and a cell may have several types on its surface. Integrins are found in all metazoa. Integrins work alongside other receptors such as cadherins, the immunoglobulin superfamily cell adhesion molecules, selectins and syndecans to mediate cellâcell and cellâmatrix interaction.