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Back to Top Causes. Horner syndrome can be caused by any interruption in a set of nerve fibers that start in the part of the brain called the hypothalamus and travel to the face and eyes. Sympathetic nerve fiber injuries can result from: 1  Injury to one of the main arteries to the brain (carotid artery).
And should any one of these sympathetic facial nerves become damaged along the way, Hornerâs syndrome can result. Hornerâs syndrome is not a disease. Itâs a group of symptoms signaling some other health malady. Symptoms of Hornerâs syndrome facial nerve paralysis include: flushing; sinking eyeball; ptosis ~ drooping eyelid; miosis ~ constricted pupil; slight elevation of lower lid; anisocoria ~ decreased pupil size; facial anhidrosis ~ decreased, no sweat