Long-term muscle use requires the delivery of oxygen and glucose to the muscle fiber to allow aerobic respiration to occur, producing the ATP required for muscle contraction. If the respiratory or circulatory system cannot keep up with demand, then energy will be generated by the much less efficient anaerobic respiration.
Then, Nicaragua, as well as Costa Rica, El Salvador, Guatemala and Honduras formed the United Provinces of Central America, but that federation quickly dissolved, and Nicaragua became an independent republic in 1838.
Granada is a city in western Nicaragua and the capital of the Granada Department.With an estimated population of 123,697 (2012), it is Nicaragua's sixth most populous city.ranada has long been a center of commerce, including timber, gold and silver. Granada's economy continues to grow as it is becoming the national tourism hub. Though Granada remains Nicaragua's sixth largest city, it is widely known for preserving some of the finest colonial-era architecture in the country.