161 reviews of The Second City Theatre Probably one of the coolest spots in Toronto! This place is always full of life and loud laughter, you go in not expecting much, and always impresses! The cast keeps changing every now and then along withâ¦
This is because indels can have a dramatic effect on the protein's structure and function. Insertion or deletion of a single letter can sometimes cause a frameshift mutation, in which the entire amino acid sequence of the resulting protein is changed.
Such type of mutations are not considered frameshift mutations because the reading frame is not altered. A frameshift mutation is caused by an insertion or deletion of base pairs in DNA sequence, which causes a shift in the translational reading frame. Frameshift mutations have a more dramatic effect on the polypeptide as compare to other mutations.