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GAD affects the way a person thinks, but the anxiety can lead to physical symptoms, as well. In addition, people with GAD often have other anxiety disorders (such as panic disorder or phobias), obsessive-compulsive disorder, clinical depression, or additional problems with drug or alcohol misuse.
Early symptoms of SCD may include: 1  Painful swelling of the hands and feet, known as dactylitis. 2  Fatigue or fussiness from anemia. 3  A yellowish color of the skin, known as jaundice, or whites of the eyes, known as icteris, that occurs when a large number of red cells hemolyze.