As in other autoimmune diseases such as lupus and rheumatoid arthritis, the bodyâs natural ability to attack invading viruses and bacteria goes haywire and mistakenly sees healthy body proteins as enemies. Redness, pain, heat and swelling signal that the immune system is on the warpath.
Formal Charge = [# valence electrons on neutral atom] â [(# lone electron pairs) + (Â½ # bonding electrons)] 1  Valence electrons = corresponds to the group number of the periodic table (for representative elements).  Lone Pairs = lone electrons sitting on the atom. Each electron counts as one and so a pair counts as two.
â is not implying that the â1 is on the O. In addition, the formal charges give us a means to determine whether a particular structure is. reasonable; or, if you have several resonance structures, the formal charges will help you determine. which resonance structure is preferred over the others. For example, you would not like to have a. structure with a positive formal charge on a highly electronegative element (such as oxygen).