Usually, an enzyme molecule has only one active site, and the active site fits with one specific type of substrate. An active site contains a binding site that binds the substrate and orients it for catalysis. Residues in the binding site form hydrogen bonds, hydrophobic interactions, or temporary covalent interactions (van der Waals) with the substrate to make an enzyme-substrate complex.
The decreased volume only disrupts the equilibrium if the moles of gaseous products and moles of gaseous reactants are unequal. If there are an equal number of moles of gaseous substances on both sides of the arrow, the change in volume has an equal effect on the concentrations of reactants and of products.
This means that as the pressure decreases, the volume increases, and as the pressure increases, the volume decreases. One way to think of this is if you push on a gas by decreasing its volume, it pushes back by increasing its pressure. This relationship is called Boyleâs Law and makes up part of the ideal gas law.heory When the volume of a gas shrinks, the gas molecules have less space to move around and so they hit their container more often. The more frequently the gas impacts the container walls, the higher the pressure. So, as volume decreases, the pressure increases.