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Translation: Taking expired doxycycline can harm your kidneys. While it is true that some drugs merely lose strength after their expiration date, many drugs (especially antibiotics!!) break down into harmful chemical products, similar to the way juice or wine can ferment if left too long. Bottom line--don't take them.
Some antibiotics that doctors prescribed in the past to treat common infections no longer work. Taking antibiotics you do not need will not help you feel better, cure your illness, or keep others from catching your infection. But taking them may cause side effects such as: 1  Nausea. 2  Diarrhea. 3  Stomach pain.4  An allergic reaction. 5  In rare cases, this reaction can require emergency care.opic Overview. Antibiotics are medicines that kill bacteria. Bacteria can cause infections such as strep throat, ear infections, urinary tract infections, and sinus infections (sinusitis).