RESULTS: In 6 patients, the mirtazapine doses ranged from 10 to 30 times the maximum recommended dose, and there were no serious adverse effects of overdose.Two patients at special risk, a 90-year-old man and a 3-year-old child, took higher-than-usual doses without serious sequelae.ONCLUSION: After an overdose of substantial multiples of mirtazapine that exceed the maximum recommended daily dosage, the new antidepressant mirtazapine appears to be safe in a limited number of cases.
The drugs that are approved to reduce the pain of diabetic peripheral neuropathy are expensive. But your doctor can prescribe much less costly drugs that might save you thousands of dollars and may work equally well. No drugs do anything more than cut the pain. To reverse the neuropathy, you have to act. A pair of articles that the American College of Physicians published in its November 4 issue of the Annals of Internal Medicine compares our choices and recommends our options.
Good control of diabetes over time is the key to treating diabetic neuropathy. There is no cure for neuropathy, but keeping your blood sugar within a target range can reduce symptoms and prevent them from getting worse.To help control your diabetes, eat food that is good for you and exercise. Controlling diabetes means maintaining blood sugar levels (A1c) within the target range.iabetic neuropathy may cause a loss of feeling in your feet. It is possible for a sore or other foot problem to go unnoticed. Without proper foot care, an untreated foot sore can lead to a serious infection or possibly amputation.