As in other autoimmune diseases such as lupus and rheumatoid arthritis, the bodyâs natural ability to attack invading viruses and bacteria goes haywire and mistakenly sees healthy body proteins as enemies. Redness, pain, heat and swelling signal that the immune system is on the warpath.
Formal Charge = [# valence electrons on neutral atom] â [(# lone electron pairs) + (Â½ # bonding electrons)] 1  Valence electrons = corresponds to the group number of the periodic table (for representative elements).  Lone Pairs = lone electrons sitting on the atom. Each electron counts as one and so a pair counts as two.
In terms of Lewis structures, formal charge is used in the description, comparison, and assessment of likely topological and resonance structures by determining the apparent electronic charge of each atom within, based upon its electron dot structure, assuming exclusive covalency or non-polar bonding.