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Translation: Taking expired doxycycline can harm your kidneys. While it is true that some drugs merely lose strength after their expiration date, many drugs (especially antibiotics!!) break down into harmful chemical products, similar to the way juice or wine can ferment if left too long. Bottom line--don't take them.
If an antibiotic has a half-life of one hour, it is safe to assume that the medication has left an individual's body after five hours. However, half-lives vary significantly from one antibiotic to another, so patients should consult their physicians or pharmacists for the precise half-lives of the specific antibiotics they've been prescribed.