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Background: Suicide is a leading cause of death in patients with bipolar disorder. Risk factors and prevention of suicide in this. illness are the focus of considerable current research. Methods: MEDLINE data base was searched for the key words âbipolar disorderâ with âsuicideâ, lithium with suicide,
In 1949, Dr. John Cade, an Australian psychiatrist, found lithium to be an effective treatment of mania. In the years that followed, lithium has become the mainstay of treatment for bipolar disorder. A steady regimen of lithium is taken to prevent manic and depressed episodes. Blood levels need to be checked periodically to avoid toxic levels.