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by | Dec 22, 2013 | Publications. VIX is a measure of expected volatility calculated as 100 times the square root of the expected 30-day variance (var) of the S&P 500 rate of return. The variance is annualized and VIX expresses volatility in percentage points.
Hereâs how you calculate TPM: 1  Divide the read counts by the length of each gene in kilobases. This gives you reads per kilobase (RPK). 2  Count up all the RPK values in a sample and divide this number by 1,000,000. This is your âper millionâ scaling factor. 3  Divide the RPK values by the âper millionâ scaling factor. This gives you TPM.