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Background: Suicide is a leading cause of death in patients with bipolar disorder. Risk factors and prevention of suicide in this. illness are the focus of considerable current research. Methods: MEDLINE data base was searched for the key words âbipolar disorderâ with âsuicideâ, lithium with suicide,
Doctors do not know what causes bipolar disorder, but it is likely a combination of biochemical, genetic, and environmental factors. Neurotransmitters (chemical messengers in the brain) that may be associated with bipolar disorder include dopamine, serotonin, and norepinephrine.