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Wiktionary (0.00 / 0 votes) Rate this definition: septum (Noun). A wall separating two cavities; a partition; as, the nasal septum. septum (Noun). A partition that separates the cells of a fruit. septum (Noun).
1). interventricular septum (septum interventriculaÂ´re corÂ´dis) the partition separating the right and left ventricles of the heart; called also ventricular septum. nasal septum a plate of bone and cartilage covered with mucous membrane that divides the nasal cavity.l. septa [L.] a wall or partition dividing a body space or cavity. Some septa are membranous, some are composed of bone, and some of cartilage. The wall separating the atria of the heart, for instance, is called the interatrial septum.