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In the nucleus of each cell, the DNA molecule is packaged into thread-like structures called chromosomes. Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.
chromosome-a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; humans have 22 chromosome pairs plus two sex chromosomes.hromosome. 1. A coiled thread of DNA found in the nucleus of a cell. 2. A rodlike body containing genes, and appearing in a cell nucleus as the cell divides.