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Wiktionary (0.00 / 0 votes) Rate this definition: septum (Noun). A wall separating two cavities; a partition; as, the nasal septum. septum (Noun). A partition that separates the cells of a fruit. septum (Noun).
A deviated septum is a common condition that involves a displacement of the septum, the wall that separates the nostrils, to one side of the nose. In adults, the septum is made of cartilage and bone, and helps to support the nose and its mucous membranes, and enables regular air flow.