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In the nucleus of each cell, the DNA molecule is packaged into thread-like structures called chromosomes. Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.
Chromatin vs. Chromosome. In the nucleus, the DNA double helix is packaged by special proteins (histones) to form a complex called chromatin. The chromatin undergoes further condensation to form the chromosome. So while the chromatin is a lower order of DNA organization, chromosomes are the higher order of DNA organization. An organismâs genetic content is counted in terms of the chromosome pairs present. e.g. humans have 23 pairs of chromosomes. 1 Structure and Formation.