Yet on the whole, the niacin flush is associated with beneficial health effects. Niacin specifically activates the high affinity G-protein coupled receptors, GPR109a and b, which then leads to release of a variety of prostaglandins that results in the flush response.
professional courtesy is something to be given by the off duty officer to an on duty officer not the other way around a working cop may use discretion on minor violations without fear of repercussions this consideration is extended to citizens and certainly can also be extended to off duty cops
As explained above, it is important to apply professional skepticism throughout the audit and document this accordingly, including when considering significant matters. Professional skepticism is often demonstrated in the various discussions held with the audit team, management, and those charged with governance. That is why it is important that we properly document such discussions to demonstrate how professional skepticism was applied.