Sex-and age-related demographics. Liver disease demonstrates a sex predilection, with males making up more than 60% of patients with chronic liver disease and cirrhosis. In general, alcoholic liver disease and viral hepatitis are the most common causes for esophageal varices in both sexes.n males with esophageal varices, alcoholic liver disease and viral hepatitis are usually the cause. Portal vein thrombosis and secondary biliary cirrhosis are the most common causes of esophageal varices in children.
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