When the site of metastasis is a single organ (such as the liver), and the cancer is confined to a single defined area within the organ, patients may benefit from local treatment directed at that single metastasis. The majority of patients diagnosed with Stage IV colon cancer have unresectable or widespread disease.
Mileage. It's common for bikers to overestimate their annual mileage and moped riders are no exception, but stating more miles than you'll actually cover can cost you when it comes to insurance premiums. Although most bikers average around 3,000 miles a year, on a 50cc scooter your mileage could well be a lot lower.
What is the average cost for motorcycle insurance in Hawaii? It really depends on your record and your age, but for a 250 cc it  will be around $400 a year for just the bike and $800 a year if you  include body insurance and I heard f â¦ rom a friend who has a 600 cc  bike and he pays around $89 a month.s 25 year old, my insurance quote for motorcycle insurance was $74/year for an Highway-grade Vespa, and for and around $348/year for Yamaha Road Star. I have a perfect drivin â¦ g record if that means anything. Anyway, hope that helps to give you some idea of what yours should cost.