Inflammation of the pancreas that gets worse over time is considered chronic pancreatitis. Persistent or chronic pancreatitis can damage the pancreas and lead to other problems,such as EPI. EPI develops when the pancreas isnât able to produce the digestive enzymes needed to digest food. When the pancreas suddenly becomes inflamed, there are two common causes: gallstones and chronic alcohol consumption.
Wiktionary(0.00 / 0 votes)Rate this definition: 1  wiseguy(Noun) One who is insolent or flippant; one who makes jokes or perpetrates pranks. 2  wiseguy(Noun) A member of the Mafia or other organized crime organization.
A 2007 film, directed and written by Joe Carnahan, about the Stage Magician, Casanova Wannabe, and newly turned mob informant Buddy Israel â a washed-up, bitter, narcissistic, alcoholic drug abuser â who gets a million-dollar bounty on his head courtesy of mob lord Primo Sperazza.