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Back to Top Causes. Horner syndrome can be caused by any interruption in a set of nerve fibers that start in the part of the brain called the hypothalamus and travel to the face and eyes. Sympathetic nerve fiber injuries can result from: 1  Injury to one of the main arteries to the brain (carotid artery).
Horner's syndrome is a common neurological disorder of the eye and facial muscles. The condition usually occurs suddenly. The most common clinical signs of Horner's syndrome are: Drooping of the eyelids on the affected side (ptosis) The pupil of the affected eye will be constricted (miosis)