When the site of metastasis is a single organ (such as the liver), and the cancer is confined to a single defined area within the organ, patients may benefit from local treatment directed at that single metastasis. The majority of patients diagnosed with Stage IV colon cancer have unresectable or widespread disease.
Mileage. It's common for bikers to overestimate their annual mileage and moped riders are no exception, but stating more miles than you'll actually cover can cost you when it comes to insurance premiums. Although most bikers average around 3,000 miles a year, on a 50cc scooter your mileage could well be a lot lower.
1 The costs of collision and other forms of motorcycle coverage vary by state as well. 2  Your bike: The make, model and year of your motorcycle will affect the cost of insurance. 3  A new bike will cost more to repair or replace than one that is five years old. Your state: Nearly every state requires motorcycle liability insurance, but the minimum limit is different from state to state. 2  The costs of collision and other forms of motorcycle coverage vary by state as well. 3  Your bike: The make, model and year of your motorcycle will affect the cost of insurance.