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Background: Suicide is a leading cause of death in patients with bipolar disorder. Risk factors and prevention of suicide in this. illness are the focus of considerable current research. Methods: MEDLINE data base was searched for the key words âbipolar disorderâ with âsuicideâ, lithium with suicide,
Bipolar Disorder. Causes of Bipolar Disorder. Both genetic elements and environmental factors can create vulnerability to the disorder, so the causes vary from person to person. While the disorder can run in families, no one has definitively identified specific genes that create risk for developing the condition.