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The duodenum is the first part of the small intestine. It is located between the stomach and the middle part of the small intestine, or jejunum. After foods mix with stomach acid, they move into the duodenum, where they mix with bile from the gallbladder and digestive juices from the pancreas.
Duodenum. The duodenum is the first part of the small intestine. The main role of the duodenum is to complete the first phase of digestion. In this section of the intestine, food from the stomach is mixed with enzymes from the pancreas and bile from the gallbladder. The enzymes and bile help break down food.