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Translation: Taking expired doxycycline can harm your kidneys. While it is true that some drugs merely lose strength after their expiration date, many drugs (especially antibiotics!!) break down into harmful chemical products, similar to the way juice or wine can ferment if left too long. Bottom line--don't take them.
Drinking any amount of alcohol with these medications can result in side effects such as flushing, headache, nausea and vomiting, and rapid heart rate. Keep in mind that some cold medicines and mouthwashes also contain alcohol. So check the label and avoid such products while taking these antibiotics. Although alcohol doesn't reduce the effectiveness of most antibiotics, it can reduce your energy and delay how quickly you recover from illness. So, it's a good idea to avoid alcohol until you finish your antibiotics and are feeling better.