161 reviews of The Second City Theatre Probably one of the coolest spots in Toronto! This place is always full of life and loud laughter, you go in not expecting much, and always impresses! The cast keeps changing every now and then along withâ¦
This is because indels can have a dramatic effect on the protein's structure and function. Insertion or deletion of a single letter can sometimes cause a frameshift mutation, in which the entire amino acid sequence of the resulting protein is changed.
Frame shift mutations. Frame shift mutations involve a deletion or insertion of one or two base pairs within a coding sequence of a gene. As the coding message is read in triplets codons and deletions the reading frame of mRNA is altered resulting in a non-sense sequence of amino acids.