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If that is not possible, such as is the case with some invasive medical procedures, including some types of dental work, then antibiotics may be recommended. There has been confusion, among doctors, dentists, and patients, about who should have antibiotics before having dental work. In the past, administration of antibiotics prior to dental work was only recommended during the first two years after surgery.
Penicillin (Pfizerpen, Pen-Vee K) Traditionally been considered the DOC for the treatment of a dental abscess. Antibiotic therapy alone, without surgical drainage, may not be effective because of poor antibiotic penetration into the abscess cavity, ineffectiveness at low pH levels, and the inoculum effect.