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Background: Suicide is a leading cause of death in patients with bipolar disorder. Risk factors and prevention of suicide in this. illness are the focus of considerable current research. Methods: MEDLINE data base was searched for the key words âbipolar disorderâ with âsuicideâ, lithium with suicide,
Causes of Bipolar Disorder. Researchers don't know exactly what causes bipolar disorder. Most likely, there's no single factor but rather multiple factors that cause bipolar disorder to develop. Genetics do play a role and increase the likelihood that someone will develop the disorder.hemicals in the brain could also predispose people to bipolar disorder [source: CCI ]. Researchers suspect that the levels of neurotransmitters dopamine, serotonin, norepinephrine, and GABA (gamma aminobutyric acid) might be involved in the disorder.