Vincristine is occasionally used as an immunosuppressant, for example, in treating thrombotic thrombocytopenic purpura (TTP) or chronic idiopathic thrombocytopenic purpura (ITP). Side effects. The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine.
Bonuses can be taxed in two ways: Percentage Method. The percentage method taxes a bonus at a flat rate, normally 25%. If the bonus is in excess of $1 million, it is taxed at a rate of 39.6%. This means that if your bonus is $10,000, and you are taxed using the percentage method, $2,500 goes to the IRS. This method is easy to calculate for both employee and employer because the bonus is taxed at a flat rate.
Bill Bischoff. Your marginal tax rate is the rate you would pay on an extra dollar of taxable income. The stated federal income tax rates are 10%, 15%, 25%, 28%, 33%, 35%, and 39.6% on ordinary income (wages, bonuses, self-employment income, interest, short-term capital gains, and the like).