Commercial Off-The-Shelf (COTS) Definition - What does Commercial Off-The-Shelf (COTS) mean? Commercial off-the-shelf (COTS) is a term that references non-developmental items (NDI) sold in the commercial marketplace and used or obtained through government contracts. The set of rules for COTS is defined by the Federal Acquisition Regulation (FAR).
Acromegaly is usually caused by a non-cancerous tumor in the pituitary gland called a pituitary adenoma. The tumor produces too much GH and raises the level of GH in the blood. Too much GH also raises the level of insulin-like growth factor-1 (IGF-1), a hormone produced in the liver that also promotes growth. Rarely, acromegaly is caused by hormone-producing tumors in other parts of the body.
acromegaly. (medicine). A chronic condition in adults caused by hypersecretion of the growth hormone and marked by enlarged jaws, extremities, and viscera, accompanied by certain physiological changes.Äk'rÅmÄg`ÉlÄ) , adult endocrine disorder resulting from hypersecretion of growth hormone produced by the pituitary gland. Since the bones cannot increase in length after full growth is attained, there is a disproportionate thickening of bones, predominantly in the skull and small bones of the hands and feet.