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Lack of vitamin E in your diet can contribute to leg cramps. Because few foods contain sufficient amounts of vitamin E, adding a supplement to your daily diet can help. Prevention's Healing with Vitamins recommends taking 400 international units of vitamin E on a daily basis to reduce leg cramping.
This is probably the number one supplement that you can take in order to help you fight muscle cramps. The easiest way to get your daily need for potassium is to eat more fruit and vegetables. Bananas and carrots are the best way (for me) to get the potassium you need to help prevent muscle cramps.