Inflammation of the pancreas that gets worse over time is considered chronic pancreatitis. Persistent or chronic pancreatitis can damage the pancreas and lead to other problems,such as EPI. EPI develops when the pancreas isnât able to produce the digestive enzymes needed to digest food. When the pancreas suddenly becomes inflamed, there are two common causes: gallstones and chronic alcohol consumption.
Wiktionary(0.00 / 0 votes)Rate this definition: 1  wiseguy(Noun) One who is insolent or flippant; one who makes jokes or perpetrates pranks. 2  wiseguy(Noun) A member of the Mafia or other organized crime organization.
Context examples: a smart businessman / an astute tenant always reads the small print in a lease / he was too shrewd to go along with them on a road that could lead only to their overthrow. Similar: smart (showing mental alertness and calculation and resourcefulness).