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The maximum dose for domperidone is 20 mg 4 times per day. The suggested beginning dose is 10 mg 4 times per day for 1 week, then increasing to 20 mg 4 times per day. This should be increased gradually as per the instructions in the individual protocols.
An adequate trial of 6-12 mg. b.i.d. should beattempted before using higher dosages.11. Lurasidone: An adequate trial with a daily dose of between 40and 160 mg. for schizophrenia or 20-120 mg. for bipolardisorder should be attempted before using higher dosages.VIII. GENERAL HEALTH-RELATED ASSESSMENT AND MONITORING FOR INDIVIDUALSRECEIVING ANTIPSYCHOTIC MEDICATIONS 1.iprasidone: An adequate trial with a dose of 40 mg. b.i.d.should be attempted before using higher doses. Doses above80 mg. b.i.d. have not been shown to be clearly more effectiveand therefore require clinical documentation of reasoning.Safety above 100 mg.