DEA 3.0 System: Dogs may have a DEA 3 system of blood type, if their blood has two antigens, DEA 3.0 and DEA Null. This is a rare type of blood and occurs in only in 5 â 6% of dogs. The most common breed with a DEA 3.0 positive type blood are grey hounds, in which 23% of all population is considered positive. If the dog is incompatible for this blood type and is transfused, erythrocytes or blood cells are usually replaced in 3 â 5 days, automatically.
Executive Summary. 1  The bloodâbrain barrier (BBB) is a significant obstacle to therapeutic delivery for CNS disorders. Among various strategies, nanobiotechnology plays an important role in facilitating drug delivery across the BBB. 2  Desirable characteristics of the ideal method of therapeutic delivery across the BBB are described in this article.
Some of the smaller molecules get through, but not the whole suite of drugs intended. Doctors don't know for sure, but it seems that in order to cross the blood-brain barrier, only molecules less than 800-1000 atomic mass units (amu) in molecular weight can get through.Lipid solubility seems to be another factor which facilitates passing through the blood-brain barrier.Water soluble molecules don't usually penetrate into brain tissue, even when very small. The molecules of essential oils are all not only small, but lipid soluble as well.he American Medical Association (AMA) has said that if they could find an agent that would pass the blood-brain barrier, they would be able to find cures for ailments such as Lou Gehrig's disease, multiple sclerosis, Alzheimer's disease, and Parkinson's disease.