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Wiktionary (0.00 / 0 votes) Rate this definition: septum (Noun). A wall separating two cavities; a partition; as, the nasal septum. septum (Noun). A partition that separates the cells of a fruit. septum (Noun).
Deviated Septum Repair (septoplasty) The nasal septum is the wall between the left and right nostrils, separating the two nasal passages or airways. It is made of thin bone in the back and cartilage in the front, supporting the nose and directing airflow.