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The plaques of atherosclerosis cause the three main kinds of cardiovascular disease 1  : Coronary artery disease: Stable plaques in the heart's arteries cause angina (chest pain on exertion). 2  Sudden plaque rupture and clotting causes heart muscle to die.3  This is a heart attack, or myocardial infarction.his progressive process silently and slowly blocks arteries, putting blood flow at risk. Atherosclerosis is the usual cause of heart attacks, strokes, and peripheral vascular disease -- what together are called  cardiovascular disease ..
Ashd (atherosclerotic heart disease) Overview. Another name for Ashd (atherosclerotic heart disease) is Coronary Artery Disease. What is coronary artery disease? A person with coronary artery disease has narrowing of the arteries that supply blood and oxygen to the heart. Coronary artery disease is caused by atherosclerosis, which is also called hardening of the arteries. As the narrowing worsens, the arteries become unable to supply enough oxygen to meet demand.