1 The Democratic Party has changed significantly during its more than two centuries of existence. During the 19th century the party supported or tolerated slavery, and it opposed civil rights reforms after the American Civil War in order to retain the support of Southern voters.
There are many causes of scoliosis, including congenital spine deformities (those present at birth, either inherited or caused by the environment), neuromuscular problems, genetic conditions, and limb length inequality.
For example, small vessel disease can occur as the result of an inherited disorder called cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). This is caused by a faulty gene that makes the blood vessels in the brain more susceptible to changes.