1 Cold hands and Itching skin and Cold feet (10 causes). 2  Cold hands and Itching skin and Weakness (10 causes). 3  Cold hands and Itching skin and Breathing difficulties (9 causes). 4  Cold hands and Itching skin and Confusion (9 causes).
Rheumatoid factor (RF) Rheumatoid factor (RF) is a blood test that measures the amount of the RF antibody in the blood. Most of the time, blood is drawn from a vein located on the inside of the elbow or the back of the hand. In infants or young children, a sharp tool called a lancet may be used to puncture the skin.
Rheumatoid nodules usually occur in patients with severe RA. Nearly all RA patients with nodules test positive for rheumatoid factor. Rheumatoid factor is positive in 70% to 80% of people with RA. Studies show that when RA is linked with a positive rheumatoid factor test, it may indicate more aggressive disease. Other factors may increase the chance of RA nodules.