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The first is intrinsic lung diseases or diseases of the lung parenchyma. The diseases cause inflammation or scarring of the lung tissue (interstitial lung disease) or result in filling of the air spaces with exudate and debris (pneumonitis). These diseases can be characterized according to etiological factors.estrictive lung diseases are characterized by a reduction in FRC and other lung volumes because of pathology in lungs, pleura, or the structures of the thoracic cage. The distensibility of the respiratory system is called compliance, the volume change produced by a change in the distending pressure.
Interstitial Lung Disease. Interstitial lung disease (ILD) is a general term for a group of conditions that cause scarring, called fibrosis, or inflammation of the lungs and gradually interferes with breathing. The diagnosis and management of ILD is often complex, and requires input from doctors across several areas of expertise. The UCSF Interstitial Lung Disease Program evaluates all forms of interstitial lung disease. The following is a list of some of these conditions: