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James Madison introduced 12 amendments to the First Congress in 1789. Ten of these would go on to become what we now consider to be the Bill of Rights. One was never passed, while another dealing with Congressional salaries was not ratified until 1992, when it became the 27th Amendment.
Durham-Humphrey Amendment. This amendment to the Food, Drug, and Cosmetic Act, also known as the Prescription Drug Amendment, was signed into law by President Harry S. Truman on October 26, 1951.he other sponsor of this amendment was Carl Durham, a pharmacist representing North Carolina in the House of Representatives. The Durham-Humphrey Amendment, enacted in 1951, resolved the issues left open by the 1938 Act.