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Pulmonary surfactant is a surface-active lipoprotein complex (phospholipoprotein) formed by type II alveolar cells. The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions.
By adsorbing to the air-water interface of alveoli hydrophilic head groups in the water and the hydrophobic tails facing towards the air, the main lipid component of surfactant, dipalmitoylphosphatidylcholine (DPPC), reduces surface tension.ulmonary surfactant is a surface-active lipoprotein complex (phospholipoprotein) formed by type II alveolar cells.