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Yes my sister is 23 and just recently noticed that one pupil is larger than the other. She just recently saw the eye doctor and he didnt notice it. She has been having headaches along with the weird pupils. She doesnt complain of sensitivity she just gets headaches.
Unequal pupils is called anisocoria and is most commonly caused by HJorner syndrome or a Third nerve palsy. In both conditions, an abnormality or asymmetry of the lid will likely be noted. With Horner's, the problem is on the side with the smaller pupil; with 3rd nerve palsy, the larger pupil is the problem side. Other causes coud be trauma, vision problems, or even familial....