Vincristine is occasionally used as an immunosuppressant, for example, in treating thrombotic thrombocytopenic purpura (TTP) or chronic idiopathic thrombocytopenic purpura (ITP). Side effects. The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine.
Bonuses can be taxed in two ways: Percentage Method. The percentage method taxes a bonus at a flat rate, normally 25%. If the bonus is in excess of $1 million, it is taxed at a rate of 39.6%. This means that if your bonus is $10,000, and you are taxed using the percentage method, $2,500 goes to the IRS. This method is easy to calculate for both employee and employer because the bonus is taxed at a flat rate.
January 4th, 2012 by Manny Davis Filed under: Filing Taxes, Tax Tips. There is generally some confusion as to how bonus income is taxed. Many people mistakenly believe that the bonus they receive from their employer during the holiday season is taxed at a higher rate than regular income. Others believe that a year-end bonus could bump them into a higher tax bracket, resulting in their being subject to a higher tax rate on their total income for the year.