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About 45 people a day, more than 16,600 people a year, die from overdoses of the drugs, including methadone, morphine, and oxycodone (OxyContin) and hydrocodone combined with acetaminophen (Lortab and Vicodin). And for every death, more than 30 others are admitted to the emergency room.
The most commonly injected drugs found in pills (i.e. oxycodone, hydromorphone, morphine, oxymorphone[2]) are water soluble and it takes no heat to get them to dissolve into the water. In fact, some of the modern pills contain abuse deterrent mechanisms in which the solution will turn into a gel when heat is added.[3]