When the site of metastasis is a single organ (such as the liver), and the cancer is confined to a single defined area within the organ, patients may benefit from local treatment directed at that single metastasis. The majority of patients diagnosed with Stage IV colon cancer have unresectable or widespread disease.
Mileage. It's common for bikers to overestimate their annual mileage and moped riders are no exception, but stating more miles than you'll actually cover can cost you when it comes to insurance premiums. Although most bikers average around 3,000 miles a year, on a 50cc scooter your mileage could well be a lot lower.
But it is quite a different story when it comes to insuring your car if youâre a man or women under the age of 25 years old. For men and women between the ages of 16 to 24 years old, insurance rate differences can be huge.If you have tickets or collisions on your driving record, and youâre a young driver, you are especially penalized with skyrocketing insurance rates. 21 year old female was quoted rates that ranged from $3,370 to $7,987 whereas a 21 year old male was quoted rates from $5,826 to $9,672. With the driver training discount, the femaleâs rate reduced to $2,983 and the maleâs rate lowered to $4,867.