Normally, the Classic period in Mesoamerica is characterized as the stage in which the arts, science, urbanism, architecture, and social organization reached their peak. This period was also dominated by the influence of Teotihuacan throughout the region, and the competition between the different Mesoamerican states led to continuous warfare.
The most common name for the killer virus, the Spanish flu, implied, of course, that it originated in Spain. Perhaps this was because there were serious outbreaks in both Madrid and Seville that infected eight million people in May of 1918 alone, even almost taking out the king himself, Alfonso XIII.
On this Page. CDC researchers and their colleagues successfully reconstructed the influenza virus that caused the 1918-19 flu pandemic, which killed as many as 50 million people worldwide. A report of their work, Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus, was published in the October 7, 2005 issue of Science.