When the site of metastasis is a single organ (such as the liver), and the cancer is confined to a single defined area within the organ, patients may benefit from local treatment directed at that single metastasis. The majority of patients diagnosed with Stage IV colon cancer have unresectable or widespread disease.
Mileage. It's common for bikers to overestimate their annual mileage and moped riders are no exception, but stating more miles than you'll actually cover can cost you when it comes to insurance premiums. Although most bikers average around 3,000 miles a year, on a 50cc scooter your mileage could well be a lot lower.
Drivers: Cut the cost of your MOT. If your MOT is due, here's how you can save some money. Taking your car for its MOT is one of those really annoying tasks in life. Unfortunately, however, itâs a necessity. If you get caught driving a vehicle on the road with an expired MOT certificate, you can get a fixed penalty notice from the police of Â£60, or a court fine up to a maximum of a Â£1,000.