Normally, the Classic period in Mesoamerica is characterized as the stage in which the arts, science, urbanism, architecture, and social organization reached their peak. This period was also dominated by the influence of Teotihuacan throughout the region, and the competition between the different Mesoamerican states led to continuous warfare.
The most common name for the killer virus, the Spanish flu, implied, of course, that it originated in Spain. Perhaps this was because there were serious outbreaks in both Madrid and Seville that infected eight million people in May of 1918 alone, even almost taking out the king himself, Alfonso XIII.
During the Middle Ages, bubonic plague was known as the Black Death.. During that time many people became sick and died of pneumonia when the bubonic plague bacteria infected the lungs, called the pneumonic plague which saw the spread of the disease bacteria through coughing and sneezing.