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Bipolar disorder patients die prematurely from a wide range of causes, from heart disease to the flu, a Swedish population study showed. MedpageToday. Action Points. Note that this large Swedish registry study demonstrated a markedly increased risk of mortality among sufferers of bipolar disorder.
1 Biological differences. 2  People with bipolar disorder appear to have physical changes in their brains. 3  The significance of these changes is still uncertain but may eventually help pinpoint causes. 4  Neurotransmitters.