The lumbar vertebrae are the 5 largest and strongest of all vertebrae in the spine. These vertebrae comprise the lower back. They begin at the start of the lumbar curve (ie, the thoracolumbar junction) and extend to the sacrum.
1) Sarcoma [CHILDREN]: cancer of connective tissue or supportive tissues, inside of bones - Diagnosed during growth. 2) Carcinomas [ADULTS]: cancer of epithelial origin such as breasts, colon, pancreas, skin, lung which spreads to bone - Diagnosed peak growth periods.
There is also a disease called ampullary cancer (carcinoma of the ampulla of Vater) that starts where the bile duct and pancreatic duct meet the duodenum of the small intestine. Tumors that affect the endocrine functions of the pancreas are called neuroendocrine or islet cell tumors, but these are fairly uncommon.