The soul is divided into a rational part and an irrational part. The rational part can be further divided into a contemplative part, which studies the invariable truths of science and mathematics, and a calculative part, which deals with the practical matters of human life.
Immunoglobulin A (IgA, also referred to as sIgA) is an antibody that plays a critical role in mucosal immunity.More IgA is produced in mucosal linings than all other types of antibody combined; between three and five grams are secreted into the intestinal lumen each day.This accumulates up to 15% of the total immunoglobulin produced in the entire body.he high prevalence of IgA in mucosal areas is a result of a cooperation between plasma cells that produce polymeric IgA (pIgA), and mucosal epithelial cells that express an immunoglobulin receptor called the polymeric Ig receptor (pIgR).
Both IgA and IgG anti-gliadin antibodies (AGA) are detected in sera of patients with gluten sensitive enteropathy (celiac disease). IgG anti-gliadin antibodies are more sensitive but are less specific markers for disease compared with IgA class antibodies. IgA anti-gliadin antibodies are less sensitive but are more specific. In clinical trials, the IgA antibodies have a specificity of 97% but the sensitivity is only 71%. That means that, if a patient is IgA positive, there is a 97% probability that they have celiac disease.