Orphenadrine is used to treat muscle spasms/pain. It is usually used along with rest, physical therapy, and other treatment.
A: The negative effects of European imperialism in Africa include loss of independence, slavery, disunity among Africans, exploitation of resources and deterioration of African culture. The positive impacts include introduction of trade, education, new religion and new administration system.
The worst negative effect of the Columbian exchange was the disease which brought to the people of New World such as smallpox, measles, chicken pox, malaria, influenza, cholera and many others. Syphilis disease also passed to the Europeans.