According to Cooper (1988) '... a literature review uses as its database reports of primary or original scholarship, and does not report new primary scholarship itself. The primary reports used in the literature may be verbal, but in the vast majority of cases reports are written documents.
Reactive oxygen species. Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, and singlet oxygen. In a biological context, ROS are formed as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling and homeostasis.
The inhibitor chemicallyresembles a (one of the) substrate(s) and binds in the active site in the same way as thesubstrate(s) binds. The inhibitor, however, has a functional group, ususally a leaving group,that is replaced by a nucleophile in the enzyme active site.herefore thistype of inhibition is called suicide inhibition or affinity labeling and the inhibitor is called a suicide inhibitor. This reaction with the suicide inhibitor removes active enzyme from the system; this removal is measured as inhibition.