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Noun. 1. cation-a positively charged ion. hydrogen ion-a positively charged atom of hydrogen; that is to say, a normal hydrogen atomic nucleus. ion-a particle that is electrically charged (positive or negative); an atom or molecule or group that has lost or gained one or more electrons.
The major extracellular cation in extracellular fluids is sodium, while the major anion is chloride. In the intracellular fluid, potassium is the major cation.