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myelin sheath. noun. The insulating envelope of myelin that surrounds the core of a nerve fiber or axon and facilitates the transmission of nerve impulses. In the peripheral nervous system, the sheath is formed from the membrane of the Schwann cell, and in the central nervous system it is formed from oligodendrocytes.
Last reviewed: April 18, 2013. Myelin is an insulating layer, or sheath, that forms around nerves, including those in the brain and spinal cord. It is made up of protein and fatty substances.The purpose of the myelin sheath is to allow electrical impulses to transmit quickly and efficiently along the nerve cells.ast reviewed: April 18, 2013. Myelin is an insulating layer, or sheath, that forms around nerves, including those in the brain and spinal cord. It is made up of protein and fatty substances.