The FDA based its decision to approve Linzess on the results of two randomized, double-blind, placebo-controlled clinical studies. 90% of the patients in the trials were female. In the open-label, long-term trials, 2147 patients with IBS-C received 290 mcg of Linzess daily for up to 18 months.
1 Everyone has one of four blood types â A, B, AB, or O â which is inherited from your parents. 2  Your blood type is determined by the presence or absence of two antigens â A and B â on the surface of red blood cells.A third antigen, called Rh factor, will either be present or absent. Antigens are substances that may trigger an immune response, causing your body to launch an attack if it believes they are foreign.hile all blood is similar in its components (such as containing red cells, platelets, and plasma), it also has important characteristics that make it unique. Your blood type is determined by the presence or absence of two antigens â A and B â on the surface of red blood cells.
So there are eight blood groups you can belong to: A Rh+, A Rh-, B Rh+, B Rh-, AB Rh+, AB Rh-, O Rh+, and O Rh -, although doctors usually leave out the Rh and just say + or -. What blood type a person ends up with is determined by genetics.f your blood cells stick together when mixed with: Anti-A serum, you have type A blood Anti-B serum, you have type B blood Both anti-A and anti-B serums, you have type AB blood If your blood cells do not stick together when anti-A and anti-B are added, you have type O blood.