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Noun. 1. blood coagulation-a process in which liquid blood is changed into a semisolid mass (a blood clot). blood clotting. clotting, coagulation, curdling-the process of forming semisolid lumps in a liquid.1  Facebook.oun. 1. blood coagulation-a process in which liquid blood is changed into a semisolid mass (a blood clot). blood clotting. clotting, coagulation, curdling-the process of forming semisolid lumps in a liquid.
Medical Definition of COAGULATION. 1. b: the process by which such change of state takes place consisting of the alteration of a soluble substance (as a protein) into an insoluble form or of the flocculation or separation of colloidal or suspended matter. 2.: a substance or body formed by coagulation: coagulum.3.. b: the process by which such change of state takes place consisting of the alteration of a soluble substance (as a protein) into an insoluble form or of the flocculation or separation of colloidal or suspended matter. 2. : a substance or body formed by coagulation: coagulum. 3.