When the disease worsens, the ESR increases; when the disease improves, the ESR decreases. The ESR doesn't always follow the course of cancer. ESR is called an acute-phase reactant test, meaning that it reacts to acute conditions in the body, such as infection or trauma.
During menstruation, the thick lining of your uterus (womb) breaks away. As you menstruate, anticoagulants are released that break down thick menstrual blood before it leaves your body. During a heavy flow, blood is expelled faster and the anticoagulants may not have enough time to break down the blood.
Women with fibroids may have an increased amount of menstrual bleeding, although many women with fibroids do not have this problem. There are a number of theories as to why heavy bleeding might happen. At the time of the menstrual period, when the uterine lining is shed, the inside of the uterus is raw and bleeding.