Any disorder and/or defect in the circulatory system, which is more or less related to heart disease, can affect the overall metabolism of the body. â Coronary heart disease or arteriosclerosis is a condition in which there is formation of plaque in the arterial walls.
Prolactin-producing tumors. The most common pituitary tumor, a prolactinoma, causes an overproduction of prolactin, a hormone that helps control sexual function. In women, the tumor can cause menstruation to stop (amenorrhea) or inappropriate production of milk by the breasts (galactorrhea).
What causes gigantism? Gigantism is almost always caused by a benign adenoma in the pituitary gland. An adenoma is a non-cancerous tumour and in the case of gigantism causes secretion of too much growth hormone. Pituitary tumours can be small in size (micro-adenoma) or large (macro-adenoma).