When the disease worsens, the ESR increases; when the disease improves, the ESR decreases. The ESR doesn't always follow the course of cancer. ESR is called an acute-phase reactant test, meaning that it reacts to acute conditions in the body, such as infection or trauma.
During menstruation, the thick lining of your uterus (womb) breaks away. As you menstruate, anticoagulants are released that break down thick menstrual blood before it leaves your body. During a heavy flow, blood is expelled faster and the anticoagulants may not have enough time to break down the blood.
1 Polyps. 2  Small, benign growths on the lining of the uterus (uterine polyps) may cause heavy or prolonged menstrual bleeding. 3  Polyps of the uterus most commonly occur in women of reproductive age as the result of high hormone levels.