Sawako Kuronuma (é»æ²¼ ç½å­ Kuronuma Sawako) is the main protagonist of the series Kimi ni Todoke.
When the intensity, duration, and/or frequency of anxiety become distressful and chronic, such that it interferes with a person's functioning, it is often referred to as pathological anxiety.Anxiety disorders represent variant forms of this pathological anxiety.hese three factors-duration, intensity, and frequency-distinguish normal, adaptive anxiety from abnormal, pathological anxiety. As such, abnormal anxiety is different from normal anxiety because it is disproportionate to the situation that elicited the anxious response.
The following are the most likely causes of PMS anxiety: 1  Cortisol Increase Studies have shown that before a woman's period, a stress hormone known as cortisol tends to increase. 2  In many ways, anxiety is a form of long term stress, and stress is known to make anxiety symptoms worse.