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Use of COLCRYS. COLCRYS (colchicine, USP) 0.6 mg tablet is a prescription medicine used in adults to prevent and treat gout flares. COLCRYS is not a pain medicine and should not be taken to treat pain related to other conditions. Individual results may vary.
Colchicine is an alternative for those unable to tolerate NSAIDs in gout. At high doses, side effects (primarily gastrointestinal upset) limit its use. At lower doses, which are still effective, it is well tolerated.vailability of tubulin is essential to mitosis, so colchicine effectively functions as a mitotic poison or spindle poison. The mitosis-inhibiting function of colchicine has been of great use in the study of cellular genetics.