Sawako Kuronuma (é»æ²¼ ç½å­ Kuronuma Sawako) is the main protagonist of the series Kimi ni Todoke.
When the intensity, duration, and/or frequency of anxiety become distressful and chronic, such that it interferes with a person's functioning, it is often referred to as pathological anxiety.Anxiety disorders represent variant forms of this pathological anxiety.hese three factors-duration, intensity, and frequency-distinguish normal, adaptive anxiety from abnormal, pathological anxiety. As such, abnormal anxiety is different from normal anxiety because it is disproportionate to the situation that elicited the anxious response.
1 Experts donât know the exact causes of anxiety disorders. Your genetics, environment, and personal history likely play a part.  Certain parts of the brain, including the amygdala and hippocampus, are being studied for their role in causing anxiety.