Any disorder and/or defect in the circulatory system, which is more or less related to heart disease, can affect the overall metabolism of the body. â Coronary heart disease or arteriosclerosis is a condition in which there is formation of plaque in the arterial walls.
Prolactin-producing tumors. The most common pituitary tumor, a prolactinoma, causes an overproduction of prolactin, a hormone that helps control sexual function. In women, the tumor can cause menstruation to stop (amenorrhea) or inappropriate production of milk by the breasts (galactorrhea).
Most common causes of pituitary malfunction include: 1  Genetic conditions such as Kallmanâs Syndrome or Prader-Willi Syndrome. 2  Pituitary tumors (cancerous and benign) 3  Hyperprolactinemia. 4  Head trauma. 5  Various Medications. 6  Auto-immune disorders.