While carcinogenic contaminants are the primary concern, PEG compounds themselves show some evidence of genotoxicity vi,vii and if used on broken skin can cause irritation and systemic toxicity.
The average age of menopause in the United States is about 51. About one out of twenty women have late menopause (after age 55) while another 5% stop having periods between the ages of 40 and 45 (early menopause). The age of menopause is reduced by two years in women who smoke.
Most premenopausal women experience changes in their menstrual cycle. When estrogen levels begin to drop, the follicular phase of the cycle may be shortened, and this can shorten the total cycle from 28â30 days to 24â26 days, resulting in more frequent periods. On the other hand, some women begin having longer cycles because they are not ovulating as frequently.