Trazodone (Deseryl, Molipaxin, Trittico, Thombran, Trialodine) Trazodone is a tetracyclic antidepressant with sedative and antianxiety actions. It has been in use in the US since 1982. Trazodone (Trade Names: Deseryl) is an antidepressant with many other uses.
Gastric cancer is not a common cause of haematemesis and melaena but a gastric ulcer may bleed and prove to be malignant on biopsy. Duodenum Duodenal ulcer is traditionally the most common cause of haematemesis and melaena.
Hyperpigmentation can be caused by sun damage, inflammation, or other skin injuries, including those related to acne vulgaris. People with darker skin tones are more prone to hyperpigmentation, especially with excess sun exposure. Many forms of hyperpigmentation are caused by an excess production of melanin. Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis.