Accepted Applicants Profile. 1  JHU SAT Scores: 1980 - 2260. 2  JHU ACT Scores: 30 - 34. 3  JHU Average GPA: 3.75 - 3.96.
What is allopurinol (Zyloprim)? Allopurinol reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones. Allopurinol is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment. Allopurinol may also be used for purposes not listed in this medication guide.
Certain textbooks/references suggest a maximum dose of allopurinol (Xyloprim, Lopurin) in patients with renal insufficiency. Presumably, this is because of renal excretion of the metabolite, oxypurinol, and fear that overdosing of allopurinol in a patient with renal insufficiency may lead to toxic epidermal necrolysis.