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What muscles does running work? Running works the quadriceps, hamstrings, gluteals, hip flexors, abs, calves, tibialis anterior and poroneal muscles. Although the exercise does not build these muscles or make them stronger, it does make them capable of greater endurance.
Making the world better, one answer at a time. Your quadriceps, hamstrings, calf muscles, hip flexors, lower back, lower abdominals, and your glutes are worked doing lunges. Your quadriceps, hamstrings, and glutes are the main muscles worked, the rest are secondary. Your quadriceps, hamstrings, calf muscles, hip flexors, lower back, lower abdominals, and your glutes are worked doing lunges.