At the terminal end of the axon is a branched structure with ends called synaptic knobs. From this structure chemical signals can be sent to neighboring neurons. Transmission of nerve impulse along the axon
When an action potential reaches the axon terminal of a motor neuron, vesicles carrying neurotransmitters (mostly acetylcholine) are exocytosed and the contents are released into the neuromuscular junction.These neurotransmitters bind to receptors on the postsynaptic membrane and lead to its depolarization.he small depolarization associated with the release of acetylcholine from one synaptic vesicle is called a miniature end-plate potential (MEPP). MEPPs are additive and lead to a greater depolarization of the postsynaptic membrane and become end plate potentials (EPPs).
Specifically, the cell bodies of the first neuron (the preganglionic neuron) are located in the thoracic and lumbar spinal cord. Axons from these neurons project to a chain of ganglia located near the spinal cord. In most cases, this neuron makes a synapse with another neuron (post-ganglionic neuron) in the ganglion.