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Review: could Prednisone cause Heartburn? Heartburn is found among people who take Prednisone, especially for people who are female, 50-59 old , have been taking the drug for 1 - 6 months, also take medication Ambien, and have Pain . We study 124,213 people who have side effects while taking Prednisone from FDA and social media. Among them, 149 have Heartburn.
What causes heartburn during pregnancy? Heartburn occurs when the valve between the stomach and the esophagus are unable to prevent stomach acid from passing back into the esophagus. During pregnancy, the hormone progesterone causes the valve to relax, which can increase the frequency of heartburn. This allows stomach acid to pass into the esophagus and irritate the lining. Heartburn and indigestion are more common during the third trimester because the growing uterus puts pressure on the intestines and the stomach. The pressure on the stomach may also push contents back up into the esophagus.