Any disorder and/or defect in the circulatory system, which is more or less related to heart disease, can affect the overall metabolism of the body. â Coronary heart disease or arteriosclerosis is a condition in which there is formation of plaque in the arterial walls.
Prolactin-producing tumors. The most common pituitary tumor, a prolactinoma, causes an overproduction of prolactin, a hormone that helps control sexual function. In women, the tumor can cause menstruation to stop (amenorrhea) or inappropriate production of milk by the breasts (galactorrhea).
1  A tumor in one of the adrenal glands is producing too much cortisol. 2  In this scenario, the adrenal tumor acts alone and the pituitary gland is normal. 3  Adrenal tumors are responsible for endogenous Cushing's syndrome in about 30% of cases.