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Chantix is notorious for causing very bad dreams. Other medications that may trigger nightmares include antibiotics (such as Avelox, Biaxin, Cipro and Levaquin), antidepressants (like Cymbalta, Effexor, Lexapro and Paxil), beta blockers (atenolol, bisoprolol, labetalol, metoprolol and propranolol) and levodopa for Parkinsonâs, among others.
For example: 1  Most of the atypical antidepressants list dry mouth, dizziness or lightheadedness as possible side effects. 2  Some antidepressants may help you sleep and are best taken at night, while others may cause insomnia. 3  Some antidepressants may cause constipation, while others may increase the risk of diarrhea. Some antidepressants may increase your appetite, resulting in weight gain, while others may cause nausea. Some antidepressants are less likely than others to cause sexual side effects.