This can lead to drastic reductions in the amount available in the systemic circulation after oral administration. E.g. propanolol (a beta blocker) needs to be given in 100mg doses orally while intravenously (avoiding first-pass metabolism) only 5mg are needed.
home > bromocriptine (parlodel) index. Bromocriptine (Parlodel) is prescription drug used to treat hyperprolactinemia, acromegaly, and signs and symptoms of Parkinson's disease. Side effects, drug interactions, dosing, storage, and pregnancy and breastfeeding safety information should be reviewed prior to taking this medication.
Cardiolipin (IUPAC name 1,3-bis(sn-3â-phosphatidyl)-sn-glycerol) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition.ardiolipin (CL) is a kind of diphosphatidylglycerol lipid. Two phosphatidic acid moieties connect with a glycerol backbone in the center to form a dimeric structure. So it has four alkyl groups and potentially carries two negative charges.