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Pompe (POM-pay) disease, also known as glycogen storage disease type II or acid maltase deficiency, is a rare genetic disorder that results in profound muscle weakness. The disease is caused by mutations in the gene that instructs the body to make an enzyme called acid alpha-glucosidase (GAA).
Some cases of Addison's disease are caused by the destruction of the adrenal cortex by bacteria, such as tuberculosis bacteria, acquired immune deficiency syndrome (AIDS), fungal infections adrenal hemorrhage, or cancer.