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Ischemic heart disease is a condition of recurring chest pain or discomfort that occurs when a part of the heart does not receive enough blood.his condition occurs most often during exertion or excitement, when the heart requires greater blood flow. Ischemic heart disease, also called coronary heart disease, is common in the United States and is a leading cause of death worldwide.
Ischemia, also spelled as ischaemia or ischaemia (/ischÃ¦mia/), ÉªËskiËmiÉ is a restriction in blood supply to, tissues causing a shortage of oxygen and glucose needed for cellular (metabolism to keep tissue). Alive ischemia is generally caused by problems with blood, vessels with resultant damage to or dysfunction of. tissueschemia results in tissue damage in a process known as ischemic cascade. The damage is the result of the build-up of metabolic waste products, inability to maintain cell membranes, mitochondrial damage, and eventual leakage of autolyzing proteolytic enzymes into the cell and surrounding tissues.