The most commonly used clostridial vaccination in cattle is the 7-way type which protects against Clostridium chauveoi (blackleg), Clostridium septicum and Clostridium sordelli (malignant edema), Clostridium novyi (black disease), and three types of Clostridium perfringens (enterotoxemia).
Langerhans cell histiocytosis is a disorder in which excess immune system cells called Langerhans cells build up in the body. Langerhans cells, which help regulate the immune system, are normally found throughout the body, especially in the skin, lymph nodes, spleen, lungs, liver, and bone marrow.
Studies suggest that sunlight apparently causes not only localized damage to the immune function of skin cells exposed to the light, but perhaps also systemic changes to the immune system protecting other parts of the body. - Damage or even kill certain cells near the skin's surface, called Langerhans cells.