1 If the test statistic follows the t distribution, then the decision rule will be based on the t distribution. The appropriate critical value will be selected from the t distribution again depending on the specific alternative hypothesis and the level of significance.  The third factor is the level of significance.
Often there are no, or only mild, symptoms. When it affects the lungs there may be wheezing, cough, shortness of breath, or chest pain. Some may have Lofgren's syndrome in which there is fever, large lymph nodes, arthritis, and a rash known as erythema nodosum. The cause of sarcoidosis is unknown.
In addition to the lungs and lymph nodes, the organs more likely than others to be affected by sarcoidosis are the liver, skin, heart, nervous system, and kidneys, in that order of frequency. Sarcoidosis is sometimes named according to the organ involved.