Enalapril is an angiotensin converting enzyme inhibitor (or ACE inhibitor). What this means is that enalapril stops the angiotensin converting enzyme from producing a compound called angiotensin-ll, which is a potent vasoconstrictor.
An anticoagulation effect generally occurs within 24 hours after warfarin administration. However, peak anticoagulant effect may be delayed 72 to 96 hours. The duration of action of a single dose of racemic warfarin is 2 to 5 days. The effects of COUMADIN may become more pronounced as effects of daily maintenance doses overlap.
When you start taking Coumadin, eat your usual amount of vitamin K-containing foods while your doctor finds the right Coumadin dose for you. While you are taking Coumadin, be sure to tell your doctor if you change your diet or eating pattern because this is likely to change your vitamin K intake. Your doctor can monitor your PT/INR test closely when your diet changes and can adjust your Coumadin as needed.