Eczema Causes. Doctors don't know exactly what causes eczema. The most common type of eczema -- atopic dermatitis -- resembles an allergy. But the skin irritation, which is more often seen in children rather than adults, is not an allergic reaction.The current thinking is that eczema is caused by a combination of factors that include: 1  Genetics.czema Causes. Doctors don't know exactly what causes eczema. The most common type of eczema -- atopic dermatitis -- resembles an allergy. But the skin irritation, which is more often seen in children rather than adults, is not an allergic reaction.
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