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Noun. 1. blood coagulation-a process in which liquid blood is changed into a semisolid mass (a blood clot). blood clotting. clotting, coagulation, curdling-the process of forming semisolid lumps in a liquid.1  Facebook.oun. 1. blood coagulation-a process in which liquid blood is changed into a semisolid mass (a blood clot). blood clotting. clotting, coagulation, curdling-the process of forming semisolid lumps in a liquid.
Coagulation - procoagulants. The third step, coagulation or blood clotting, reinforces the platelet plug with fibrin threads that act as a molecular glue for the aggregated platelets. The resulting blood clot (fibrin mesh) is quite effective in sealing larger breaks in a blood vessel. Blood is transformed from a liquid to a gel in a multistep process that involves a series of substances called clotting factors, or procoagulants.