Orange Is the New Black is an American comedy-drama series created by Jenji Kohan, which premiered on July 11, 2013, on Netflix.
An earlier report published in April 2011 by the Williams Institute estimated that 3.8 percent of Americans identified as gay/lesbian, bisexual, or transgender: 1.7 percent as lesbian or gay, 1.8 percent as bisexual, and 0.3 percent as transgender.
The answer is uncertain. It is estimated that there are about 700,000 transgender people in the US, but that estimate involves a lot of guesswork. See Why We Don't Know The Size Of The Transgender Population.