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Diphenhydramine, Lorazepam, and Dexamethasone in Treating Nausea and Vomiting Caused By Chemotherapy. This study has been terminated. RATIONALE: Diphenhydramine, lorazepam, and dexamethasone may help lessen or prevent nausea and vomiting in patients treated with chemotherapy. It is not yet known whether diphenhydramine, lorazepam, and dexamethasone are more effective than standard therapy in treating nausea and vomiting caused by chemotherapy.
Benadryl for Kitty Nerves. Humans who have taken Benadryl know that one of its side effects is a sedative one. In fact, the active ingredient in Benadryl, diphenhydramine, is sometimes prescribed to both humans and cats for this effect. It also has an anti-nausea effect, which can be useful in preventing nervous cats from getting sick. Benadryl is often recommended for traveling cats for these reasons. It helps calm them and prevent motion sickness. The recommended dosage is 0.5 to 2 mg per pound of your cat's weight every 8 to 12 hours.