At the terminal end of the axon is a branched structure with ends called synaptic knobs. From this structure chemical signals can be sent to neighboring neurons. Transmission of nerve impulse along the axon
When an action potential reaches the axon terminal of a motor neuron, vesicles carrying neurotransmitters (mostly acetylcholine) are exocytosed and the contents are released into the neuromuscular junction.These neurotransmitters bind to receptors on the postsynaptic membrane and lead to its depolarization.he small depolarization associated with the release of acetylcholine from one synaptic vesicle is called a miniature end-plate potential (MEPP). MEPPs are additive and lead to a greater depolarization of the postsynaptic membrane and become end plate potentials (EPPs).
1 The vesicle merges with the presynaptic membrane. 2  The presynaptic membrane and vesicle now forms a continuous membrane, so that the neurotransmitter is released into the synaptic cleft. 3  This process is called exocytosis.