Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
Pakistan's 2nd most populous city, Lahore, is only about half the size, with just 6.3 million people, but is still the world's 15th most populous city. Pakistan has six additional cities that have passed the one million population mark.
Islamabad was built during the 1960s to replace Karachi as Pakistan's capital. The city's master-plan divides the city into eight zones, including administrative, diplomatic enclave, residential areas, educational sectors, industrial sectors, commercial areas, and rural and green areas.