Myasthenic crisis is a life-threatening condition, which is defined as weakness from acquired myasthenia gravis that is severe enough to necessitate intubation or to delay extubation following surgery [ 1 ]. The respiratory failure is due to weakness of respiratory muscles.
Generic Name: Tizanidine. Generic for Zanaflex* (Tizanidine) is an oral medication used to treat muscle spasms caused by multiple sclerosis and spinal cord injury. Tizanidine is a short-acting muscle relaxant that temporarily relaxes the muscle tone and treats muscle tightness and cramping.f any side effects of Generic for Zanaflex* develop or change in intensity, the doctor should be informed as soon as possible. Generic for Zanaflex* can cause side effects such as dry mouth, constipation, dizziness, stomach pain, diarrhea, sweating, and skin rash.
BRAND NAME: Zanaflex. DRUG CLASS AND MECHANISM: Tizanidine is a skeletal muscle relaxant. It works on alpha2 receptors in the central nervous system (brain and spinal cord) and blocks nerve impulses from reaching muscles which produces muscle relaxation. The FDA approved tizanidine in November 1996.RESCRIBED FOR: Tizanidine is used for the treatment and management of skeletal muscle spasticity. Spasticity may be due to multiple sclerosis or spinal cord injury. DOSING: Initially take 2 - 4 mg by mouth every 6 to 8 hours for up to 3 doses in 24 hours.