Sawako Kuronuma (é»æ²¼ ç½å­ Kuronuma Sawako) is the main protagonist of the series Kimi ni Todoke.
When the intensity, duration, and/or frequency of anxiety become distressful and chronic, such that it interferes with a person's functioning, it is often referred to as pathological anxiety.Anxiety disorders represent variant forms of this pathological anxiety.hese three factors-duration, intensity, and frequency-distinguish normal, adaptive anxiety from abnormal, pathological anxiety. As such, abnormal anxiety is different from normal anxiety because it is disproportionate to the situation that elicited the anxious response.
Scientists believe that many factors combine to cause anxiety disorders: 1  Genetics. Some families will have a higher than average numbers of members experiencing anxiety issues, and studies support the evidence that anxiety disorders run in families. 2  Environment.