Any disorder and/or defect in the circulatory system, which is more or less related to heart disease, can affect the overall metabolism of the body. â Coronary heart disease or arteriosclerosis is a condition in which there is formation of plaque in the arterial walls.
Prolactin-producing tumors. The most common pituitary tumor, a prolactinoma, causes an overproduction of prolactin, a hormone that helps control sexual function. In women, the tumor can cause menstruation to stop (amenorrhea) or inappropriate production of milk by the breasts (galactorrhea).
These tumors produce excess GH. According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), more than 95% of people with acromegaly have a pituitary adenoma. Tumors outside the pituitary gland can also cause acromegaly, but this is rare.