While carcinogenic contaminants are the primary concern, PEG compounds themselves show some evidence of genotoxicity vi,vii and if used on broken skin can cause irritation and systemic toxicity.
The average age of menopause in the United States is about 51. About one out of twenty women have late menopause (after age 55) while another 5% stop having periods between the ages of 40 and 45 (early menopause). The age of menopause is reduced by two years in women who smoke.
Females begin their menstrual cycle during puberty at the onset of menarche, their first menstrual period. Females continue to have many menstrual cycles throughout their lives until menopause occurs between ages 40 to 60. The average menstrual cycle lasts about 28 days, but can last anywhere from 24 to 42 days.