Any disorder and/or defect in the circulatory system, which is more or less related to heart disease, can affect the overall metabolism of the body. â Coronary heart disease or arteriosclerosis is a condition in which there is formation of plaque in the arterial walls.
Prolactin-producing tumors. The most common pituitary tumor, a prolactinoma, causes an overproduction of prolactin, a hormone that helps control sexual function. In women, the tumor can cause menstruation to stop (amenorrhea) or inappropriate production of milk by the breasts (galactorrhea).
In adults, a tumor is the most common cause of too much GH production: Pituitary tumors. Most cases of acromegaly are caused by a noncancerous (benign) tumor (adenoma) of the pituitary gland. The tumor secretes excessive amounts of growth hormone, causing many of the signs and symptoms of acromegaly.