The most commonly used clostridial vaccination in cattle is the 7-way type which protects against Clostridium chauveoi (blackleg), Clostridium septicum and Clostridium sordelli (malignant edema), Clostridium novyi (black disease), and three types of Clostridium perfringens (enterotoxemia).
Langerhans cell histiocytosis is a disorder in which excess immune system cells called Langerhans cells build up in the body. Langerhans cells, which help regulate the immune system, are normally found throughout the body, especially in the skin, lymph nodes, spleen, lungs, liver, and bone marrow.
The Langerhanâs cells are also found in this layer, these cells interact with the white blood cells and serves as the immune defense. Layers of the Epidermis (from deepest to most superficial layer). Stratum basale (Stratum germinativum). This is the deepest layer of the skin where mitosis occurs.