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Pompe (POM-pay) disease, also known as glycogen storage disease type II or acid maltase deficiency, is a rare genetic disorder that results in profound muscle weakness. The disease is caused by mutations in the gene that instructs the body to make an enzyme called acid alpha-glucosidase (GAA).
Addison's disease has many causes, such as. 1  destruction of the adrenal glands by infection; 2  their destruction by an autoimmune attack; 3  an inherited mutation in the ACTH receptor on adrenal cells.