This can lead to drastic reductions in the amount available in the systemic circulation after oral administration. E.g. propanolol (a beta blocker) needs to be given in 100mg doses orally while intravenously (avoiding first-pass metabolism) only 5mg are needed.
home > bromocriptine (parlodel) index. Bromocriptine (Parlodel) is prescription drug used to treat hyperprolactinemia, acromegaly, and signs and symptoms of Parkinson's disease. Side effects, drug interactions, dosing, storage, and pregnancy and breastfeeding safety information should be reviewed prior to taking this medication.
macroprolactinoma. [- 1 prÅlakâ²tinÅâ²mÉ] 2  a prolactin-secreting pituitary tumor more than 10 mm in diameter that causes serum prolactin levels higher than 500 ng/mL. Bromocriptine is used with some success to shrink tumor size before surgery. Frequent monitoring of endocrine status is indicated for the remainder of the patient's life after therapy.