Idiopathic thrombocytopenic purpura (ITP) Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. People with the disease have too few platelets in the blood. ITP is sometimes called immune thrombocytopenic purpura or simply, immune thrombocytopenia.
sex-linked disorder - any disease or abnormality that is determined by the sex hormones; hemophilia is determined by a gene defect on an X chromosome. bleeder's disease, haemophilia, hemophilia - congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son.
Unlike the paired autosomes, in which each member normally carries alleles (forms) of the same genes, the paired sex chromosomes do not carry an identical complement of genetic information. The X chromosome, being larger, carries many more genes than does the Y. Traits controlled by genes found only on the X chromosome are said to be sex-linked (see linkage group). Recessive sex-linked traits, such as hemophilia and redâgreen colour blindness, occur far more frequently in men than in women.