Tumor lysis syndrome. Tumor lysis syndrome (TLS) is a group of metabolic abnormalities that can occur as a complication during the treatment of cancer, where large amounts of tumor cells are killed off (lysed) at the same time by the treatment, releasing their contents into the bloodstream.
The Trevi Fountain that stands in Trevi Square today was designed by Roman architect Nicola Salvi. Building began in 1732 and concluded three decades later. Before his death in 1751, Salvi chose young artist Giuseppe Pannini as his successor.
The fountain, which is designed like a monumental triumphal arch, was built against a wall of the Palazzo Poli. It measures twenty meters wide and twenty-six meters high and occupies more than half the square. The central figure of the fountain, standing in a large niche, is Neptune, god of the sea.