Treatment at the time of acute symptomsshould be based on the clinical diagnosis at thetime of illness, as most patients with ADEM (oran ADEM-like illness that is eventually deter-mined to be the first manifestation of MS) areprofoundly ill.High-dose corticosteroids are first-line treatmentof ADEM.
acceptance - the act of taking something that is offered; her acceptance of the gift encouraged him; he anticipated their acceptance of his offer. acquisition - the act of contracting or assuming or acquiring possession of something; the acquisition of wealth; the acquisition of one company by another.
A best-offer scenario generally means the seller plans to accept the best offer, or counter only the offers it deems the strongest. Sellers do not have to respond to every offer they receive and usually don't formally reject offers in writing.