During the ratification debate in Virginia, Madison promised that a bill of rights would be added after ratification. His promise reassured the convention and the Constitution was approved in that state by the narrowest margin. New York soon followed, but submitted proposed amendments.
Bacteria reproduce by a process known as binary fission, while eukaryote such as animal cells, reproduce by mitosis. In binary fission one bacterium slowly separates into two bacteria which then also divide and the life cycle continues as this process repeats over and over.
Prokaryote like bacteria and unicellular organisms reproduce asexually by cell division or binary fission of the parent cell. This is a type of reproduction done by a single organism without production of gametes.