ATN does not rapidly improve following the administration of large-volume intravenous fluid. Treatment for Acute Tubular Necrosis (ATN) Management relies on aggressive treatment of the factors that precipitated ATN. One exception is the treatment of ATN associated with the breakdown of muscle fibers caused by a crush injury.
Ribosomes are found âfreeâ in the cytoplasm or bound to the endoplasmic reticulum (ER) to form rough ER. In a mammalian cell there can be as many as 10 million ribosomes. Several ribosomes can be attached to the same mRNA strand, this structure is called a polysome. Ribosomes have only a temporary existence.
1 The subunits of the ribosome are synthesized by the nucleolus. 2  The subunits of ribosomes join together when the ribosomes attaches to the messenger RNA during the process of protein synthesis. 3  Ribosomes along with a transfer RNA molecule (tRNA), helps to translate the protein-coding genes in mRNA to proteins.ibosome Structure. 1  Ribosomes in a cell are located in two regions of the cytoplasm. 2  They are found scattered in the cytoplasm and some are attached to the endoplasmic reticulum. 3  When the ribosomes are bound to the ER there are known as the rough endoplasmic reticulum.