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WE give liquid and pill form benadryl quite often to dogs. The rule of thumb is 1mg per pâ¦ound. For example: a 25lb dog can take 25mg of benadryl.   Answer   I read on a veterinarian hospital page that you were NOT supposed to give the liquid form of benadryl to dogs.
But there are other questions you should ask your vet: how much Benadryl can I give my dog, and is Benadryl safe for dogs. The general guideline for how much Benadryl can I give my dog is 1mg of Benadryl (diphenhydramine) for each pound of body weight, 3 times per day (which means every 8 hrs).