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DLBCL is an aggressive (fast-growing) lymphoma. It can arise in lymph nodes or outside of the lymphatic system, in the gastrointestinal tract, testes, thyroid, skin, breast, bone, or brain. Although DLBCL is the most common form of NHL, there are several subtypes that may affect the prognosis (how well patients will do with standard treatment) and treatment.
Sarcomas spread most commonly to the lungs. They can also spread to other bones (ie. arise from a bone and spread to other bones) and to the liver. These are the most common sites of spread. Sarcomas rarely spread to lymph nodes.