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Coagulation: Coagulation, in physiology, the process by which a blood clot is formed. The formation of a clot is often referred to as secondary hemostasis, because it forms the second
Blood normally remains in its liquid state while it is within the blood vessels but when it leaves them the blood may thicken and form a gel (coagulation). Blood clotting (technically  blood coagulation ) is the process by which (liquid) blood is transformed into a solid state.This blood clotting is a complex process involving many clotting factors (incl. calcium ions, enzymes, platelets, damaged tissues) activating each other.The three stages of this process are: Prothrombinase can be formed in two ways, depending of which of two systems or pathways apply.lood normally remains in its liquid state while it is within the blood vessels but when it leaves them the blood may thicken and form a gel (coagulation). Blood clotting (technically  blood coagulation ) is the process by which (liquid) blood is transformed into a solid state.