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WE give liquid and pill form benadryl quite often to dogs. The rule of thumb is 1mg per pâ¦ound. For example: a 25lb dog can take 25mg of benadryl.   Answer   I read on a veterinarian hospital page that you were NOT supposed to give the liquid form of benadryl to dogs.
The bottle of Benadryl should have all of the information you need to determine the proper dose. It should indicate how many mg are in each mL of liquid. Typically, most benadryl liquid preparations are 12.5mg per 5mL, so in order to administer 10mg, 4mL would be required (2.5mg per mL).Dr. Drew, Dog Veterinarian. Category: Dog Veterinary.t should indicate how many mg are in each mL of liquid. Typically, most benadryl liquid preparations are 12.5mg per 5mL, so in order to administer 10mg, 4mL would be required (2.5mg per mL). Dr. Drew, Dog Veterinarian.