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Fifth disease is transmitted through respiratory droplets and contact with infected blood products. The incubation period (the time between the initial infection and the onset of symptoms) is usually between 4 and 21 days. People with fifth disease are most contagious before the onset of symptoms.ifth disease is transmitted through respiratory droplets and contact with infected blood products. The incubation period (the time between the initial infection and the onset of symptoms) is usually between 4 and 21 days. People with fifth disease are most contagious before the onset of symptoms.
The period when you're most contagious is when your symptoms are at their worst -- day 2 to day 4 of the cold.ased on previous studies, their best guess is that a person becomes contagious about two to three days before developing the usual symptoms of a cold. Second, this contagious period can last until the person no longer shows any symptoms.