So the basic answer to the question how often should I run is three to four days a week with some cross-training thrown in, if possible, and at least one day a week of rest. And one last thing: remember to have some fun, even on those days when your run is on the tougher side.
Effects of berberine in the gastrointestinal tract - a review of actions and therapeutic implications. Berberine is an isoquinoline alkaloid present in several plant species, including Coptis sp. and Berberis sp. In traditional medicine, extracts of berberine are used in the treatment of diarrhea of different origins.
These mechanisms have been linked with weight loss, healthier blood glucose levels, and other benefits. One of the interesting qualities of berberine is its low bioavailability. In lab testing on rats, berberine has been shown to have bioavailability as low as 5%. However, even with that low absorption rate, the effects of berberine are still noticeable on most users.