Tumor lysis syndrome. Tumor lysis syndrome (TLS) is a group of metabolic abnormalities that can occur as a complication during the treatment of cancer, where large amounts of tumor cells are killed off (lysed) at the same time by the treatment, releasing their contents into the bloodstream.
The Trevi Fountain that stands in Trevi Square today was designed by Roman architect Nicola Salvi. Building began in 1732 and concluded three decades later. Before his death in 1751, Salvi chose young artist Giuseppe Pannini as his successor.
From the Colosseum to the Forum, the glory of the height of the Roman Empire can still be felt. Yet, more recent landmarks draw an equal number of onlookers in a city filled with tourists. The Trevi Fountain, which was built in the 1700s, is perhaps one of Romeâs most iconic structures. Built on the site of an ancient Roman water source, it is made of the same material (travertine stone) as the Colosseum. It has appeared in films like Felliniâs La Dolce Vita.