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The liver. The liver is your largest internal organ. About the size of a football, it's located mainly in the upper right portion of your abdomen, beneath the diaphragm and above your stomach, but a small portion extends into the upper left quadrant.he liver is your largest internal organ. About the size of a football, it's located mainly in the upper right portion of your abdomen, beneath the diaphragm and above your stomach, but a small portion extends into the upper left quadrant.
The gallbladder is a pear-shaped sac located under the liver on the upper right side of the abdomen, according to MayoClinic.com. The liver produces bileâa digestive fluid that aids in the digestion of fatâand the gallbladder stores it. In response to foods, especially fats, the gallbladder releases the bile into the upper small intestine. The gallbladder is not essential to healthy digestion, so removal of the gallbladder rarely causes long-term complications.