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Research has shown that urine drug tests generally produce a false positive test more than the other drug tests. There are over 1,000 labs in the United States currently testing for drugs. Studies have shown that less than a 100 of these meet federal standards and most states do not regulate these labs.he outcome is very specific to the individual and/or the situation. 1  Here are some of the more common sources of a false drug test: 2  Pain relievers such as Advil, Uprin, Motrin. 3  Menstrual cramp medications like Midol and Trendar. 4  Ibuprofen is known to cause positive for Marijuana.