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1,4-Dihydropyridine (DHP), an important class of calcium antagonist, inhibits the influx of extracellular Ca+2 through L-type voltage-dependent calcium channels. Three-dimensional (3D) structure of calcium channel as a receptor for 1,4-dihydropyridine is a step in understanding its mode of action. Protein structure prediction and modeling tools are becoming integral parts of the standard toolkit in biological and biomedical research.
potassium channel a voltage-gated protein channel selective for the passage of potassium ions. protein channel a watery pathway through the interstices of a protein molecule by which ions and small molecules can cross a membrane into or out of a cell by diffusion.