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Opposition research. Opposition research (also called oppo) is the practice of collecting information on a political opponent or other adversary that can be used to discredit or otherwise weaken them.
At an online discussion forum, you see the phrase in regards to the OP, I think that health care is going to be pivotal in this coming election. What does this OP expression mean? The original poster is the person who started a discussion thread, and OP is used to refer back to that person as the responses grow.