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have been ruled out, a patient is diagnosed with oral leukoplakia. While the long-term history of these. lesions is impossible to predict, it is known that true leukoplakias are considered âpotentially. malignant,â meaning that they have the potential, over time, to develop into oral cancer. Oral leukoplakia occurs in 1-2% of the population and is most common in patients over age 40. It may. affect any part of the mouth.
Leukoplakia is an abnormal white area or spots on the mucous membrane lining the mouth with no clear cause. There are many conditions that present with white areas, such as thrush and lichen planus. White spots may also be caused by irritation, such as biting the cheek or lip.