The more ADH there is in the blood the harder the kidney works to reabsorb water. go back up. Negative feedback: a control process. When a hormone has had an effect on its target organ the process of negative feedback can switch the endocrine organ off.oo much water in the blood, detected by the hypothalamus. Less ADH produced by the pituitary gland. Less water reabsorbed by the kidneys, caused by ADH. Blood becomes more concentrated.
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