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Shirley is a town in Piscataquis County, Maine, United States. The town was named after Shirley, Massachusetts. The population was 233 at the 2010 census.
Maine has a current population density of just 43.1 people per square mile, which makes it the least densely populated state in New England, the American northeast and the eastern seaboard, as well as all states with an Atlantic coastline and those states east of the Mississippi River.