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Medications that can cause night sweats. Night sweats are a common side effect of many medications, such as: 1  Depression medications (antidepressants). 2  Drugs used to regulate your hormones (hormone therapy). 3  Drugs that lower the level of sugar in your blood (hypoglycemic agents).
However, there are side effects that are common to most antibiotics, regardless of class or drug: 1  Vaginal yeast infections or oral thrush (candida species): Antibiotics may also change the normal flora balance in the vagina, and lead to a fungal overgrowth. Candida albicans is a common fungus normally present in small amounts in the vagina and does not usually cause disease or symptoms.