1 Cancer. 2  All tobacco smoke contains chemicals that can cause cancer, and cigar smoke is no exception. 3  Regular cigar smoking increases the risk of several types of cancers, including cancers of the mouth, lip, tongue, throat, esophagus, larynx and lung. 4  Lung and heart disease.
Results Of the three nicotinic receptor agonists tested, [3H]cytisine displayed the highest affinity for the neu- ronal nicotinic receptor (Table 1). It had a significantly higher affinity of 0.145 + 0.011 nM (P < 0.05, Fig. 1A) as compared to KD values of 0.89 + 0.06 and 1.07 _+ 0.13 nM for [3H]nicotine (Fig.
5-hydroxytryptamine receptor antagonists (5-HT3 RAs) are a group of drugs which are used to control nausea and vomiting. They get their name through their ability to block 5-hydroxytryptamine (also known as serotonin) from activating nerves that bring about the vomiting reflex. 5-HT 3 RAs, or serotonin blockers, were originally discovered in the 1990s and are one of the newest types of anti-vomiting drugs on the market.