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Bacitracin is a powerful antibiotic, but it is rarely used internally, because it is considered toxic and difficult to control. However, the use of bacitracin ointment may be effective in reducing numerous infections that affect the skin of canines.
Bacitracin is a mixture of related cyclic peptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, first isolated in 1945. These peptides disrupt both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.acitracin is used in human medicine as a polypeptide antibiotic and is approved by the U.S. Food and Drug Administration (FDA) for use in chickens and turkeys, though use in animals contributes to antibiotic resistance.