Macrocytosis - Pathophysiology. 1  The most common cause of macrocytic anemia is megaloblastic anemia, which is the result of impaired DNA synthesis. 2  Vitamin B-12 and folate coenzymes are required for thymidylate and purine synthesis; thus, their deficiency results in retarded DNA synthesis.
(You may want to read the articles about Scales, the Major Scale, or Key Signatures first.) There are 12 different Major Scales: One with no sharps or flats, 4 with sharps, 4 with flats, and 3 with either sharps or flats depending upon enharmonic spelling. Major Scales with no sharps or flats: C Major. Major Scales with sharps: D, E, G, A. Major Scales with flats: E-flat, F, A-flat, B-flat.
The Scales. Despite the melodic complexity of their solos, country guitarists mostly rely on a few choice scales: major pentatonic, the blues scale, and the composite blues scale. The most prevalent of the three scales, major pentatonic, is a five-note scale (1â2â3â5â6) derived from the major scale (1â2â3â4â5â6â7). The scaleâs most common fingering is illustrated in Ex. 1, without regard to a specific key (use the root notes in red to help you relocate the scale to your key of choice).