itchiness (pruritus). Pruritus is the primary symptom of cholestasis and is thought to be due to interactions of serum bile acids with opioidergic nerves. In fact, the opioid antagonist naltrexone is used to treat pruritus due to cholestasis. jaundice. Jaundice is an uncommon occurrence in intrahepatic (metabolic) cholestasis, but is common in obstructive cholestasis.
The Sun is the closest star to Earth, about 93 million miles away. The Sunâs nearest neighbor, Alpha Centauri, is actually a triple-star system âthree stars bound together by gravity. Alpha Centauri A and B are two bright, closely orbiting stars with a distant, dim companion, Proxima Centauri.
Scientists think that 20 out of the 30 stars nearest to Earth are red dwarfs; however, none of them can be seen with the naked eye. The closest star to the sun, Proxima Centauri, is a red dwarf. Despite its frequent appearance, the term red dwarf does not refer to a single kind of star. It is frequently applied to the coolest objects, including K- and M-dwarfs, which are true stars, and brown dwarfs, often referred to as failed stars because they do not sustain hydrogen fusion in their cores.