Around 1875, the game of poker adopted the joker as a wild card. They have been a standard part of American playing card decks since the 1940s. Jokers as a Nickname for a Pair of Jacks. The second meaning of jokers is a slang term for a pair of jacks in Texas Hold'em.
Inheritance and Genetics of Intersex conditions. Genetics of Intersex conditions: Some intersex conditions are caused by chromosome deletions and duplications, while other conditions are due to specific chromosome mutations that may be inherited. Inheritance of Intersex conditions refers to whether the condition is inherited from your parents or runs in families. The level of inheritance of a condition depends on how important genetics are to the disease.
But the mutations we hear about most often are the ones that cause disease. Some well-known inherited genetic disorders include cystic fibrosis, sickle cell anemia, Tay-Sachs disease, phenylketonuria and color-blindness, among many others. All of these disorders are caused by the mutation of a single gene. Most inherited genetic diseases are recessive, which means that a person must inherit two copies of the mutated gene to inherit a disorder.