1 Cancer. 2  All tobacco smoke contains chemicals that can cause cancer, and cigar smoke is no exception. 3  Regular cigar smoking increases the risk of several types of cancers, including cancers of the mouth, lip, tongue, throat, esophagus, larynx and lung. 4  Lung and heart disease.
Results Of the three nicotinic receptor agonists tested, [3H]cytisine displayed the highest affinity for the neu- ronal nicotinic receptor (Table 1). It had a significantly higher affinity of 0.145 + 0.011 nM (P < 0.05, Fig. 1A) as compared to KD values of 0.89 + 0.06 and 1.07 _+ 0.13 nM for [3H]nicotine (Fig.
A serotonin antagonist is a drug used to inhibit the action at serotonin (5-HT) receptors. Methysergide is a 5-HT 2A antagonist and nonselective 5-HT1 receptor blocker. 2  It causes retroperitoneal fibrosis and mediastinal fibrosis. 3  Quetiapine blocks 5-HT 2A, 5-HT1A, dopamine receptors D1 and D2, histamine receptor H1, and A1 adrenoreceptors.