Re-consent of subjects enrolled in clinical trials initiated prior to March 7, 2012 is not required. From a practical perspective, however, investigators and sponsors may choose to include the required language in consent forms for applicable clinical trials even if study initiation will occur prior to March 7, 2012.
Climate change will have the following effects on Lyme disease: An acceleration of the tick's developmental cycle, a prolonged developmental cycle, increased egg production, increased population density, and a broader range of risk areas.
Lyme Disease Lyme disease is caused by a bacterium, Borrelia burgdorferi, which is transmitted to a person through the bite of an infected deer tick (Ixodes scapularis). Symptoms of Lyme disease include the formation of a characteristic expanding rash (erythema migrans, EM) 3-30 days after a tick bite. This rash occurs in approximately 70- 80% 1 of patients nationally.