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DLBCL is an aggressive (fast-growing) lymphoma. It can arise in lymph nodes or outside of the lymphatic system, in the gastrointestinal tract, testes, thyroid, skin, breast, bone, or brain. Although DLBCL is the most common form of NHL, there are several subtypes that may affect the prognosis (how well patients will do with standard treatment) and treatment.
Abnormal lymphocytes may divide faster than normal cells or they may live longer than they are supposed to. Lymphoma may develop in many parts of the body, including the lymph nodes, spleen, bone marrow, blood or other organs. There are two main types of lymphomas: â¢ Hodgkin lymphoma (HL) (formerly referred to as Hodgkin's lymphoma) â There are six types of HL, an uncommon form of lymphoma that involves the Reed-Sternberg cells.