Although it was already well known for the quality of its Nebbiolo grapes, the widely accepted birthdate of Barbaresco is 1894, when Cantina Sociale di Barbaresco was founded, as before that date Nebbiolo grapes from the Barbaresco area were mostly sold to Barolo producers.
Nephron, functional unit of the kidney, the structure that actually produces urine in the process of removing waste and excess substances from the blood. There are about 1,000,000 nephrons in each human kidney. The most primitive nephrons are found in the kidneys (pronephros) of primitive fish, amphibian larvae, and embryos of more advanced vertebrates.
There are two types of nephrons, distinguished by their location in the kidney. Cortical nephrons are located in the renal cortex on the outside of the organ, while juxtamedullary nephrons are located deeper in the kidney, in the renal medulla. Each nephron is made up of a renal corpuscle and a renal tubule. The renal corpuscle provides the initial filtering component, while the renal tubule is responsible for reabsorption. The corpuscle is composed of the glomerulus and Bowman's capsule.