Tumor lysis syndrome. Tumor lysis syndrome (TLS) is a group of metabolic abnormalities that can occur as a complication during the treatment of cancer, where large amounts of tumor cells are killed off (lysed) at the same time by the treatment, releasing their contents into the bloodstream.
The Trevi Fountain that stands in Trevi Square today was designed by Roman architect Nicola Salvi. Building began in 1732 and concluded three decades later. Before his death in 1751, Salvi chose young artist Giuseppe Pannini as his successor.
Sailor Fountain Pen Ink Cartridges. Sailor Pen Refills. The Sailor Pen Co., Ltd. was founded in 1911. Sailor Pen was the first company in Japan to make fountain pens and its fountain pens are still some of the most sought after today. Aside from its expensive one-of-a-kind handmade fountain pens, Sailor Pen has decided to modernize its fountain pen designs by making them more approachable and affordable.