On September 13, 1996. however, Tupac Shakur died of his wounds. Six months later, Shakurâs rap rival, Christopher Wallace, was murdered in similar circumstances in Los Angeles. No arrest has been made to date in connection with either murder.
De Quervain's may cause pain when you twist your wrist. You might also have pain if you grab something between your thumb and fingers. Many people hear a funny sound like a squeak, crackle, snap, or creak when they move the wrist or thumb. The bottom of the thumb or the side of the wrist might also be sore or swollen. This can make it hard to move your thumb or wrist. The back of the thumb and index finger may also feel numb. Sometimes de Quervain's can cause a small bump on the thumb side of the wrist. If you don't get treatment, the pain can spread up your forearm or down into your thumb.
Twitching in the left thumb may also indicate an overdose of caffeine, stimulants or amphetamines or a drug side effect to estrogen, corticosteroids or diuretics, adds MedlinePlus. Diet is also a cause of left thumb twitching, especially when an individual fails to consume a balanced diet. When the body is unable to fight off ailments, such as an autoimmune disorder, twitching is often a side effect.