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Shirley is a town in Piscataquis County, Maine, United States. The town was named after Shirley, Massachusetts. The population was 233 at the 2010 census.
Between 2002 - 2006, there were 391 infant deaths in Maine. The 2002 - 2006 infant. mortality rate in Maine was 5.6 per 1,000 live births. Three of every four deaths to infants in Maine. during this period occurred during the neonatal period (birth to 28 days of life).