ATN does not rapidly improve following the administration of large-volume intravenous fluid. Treatment for Acute Tubular Necrosis (ATN) Management relies on aggressive treatment of the factors that precipitated ATN. One exception is the treatment of ATN associated with the breakdown of muscle fibers caused by a crush injury.
Ribosomes are found âfreeâ in the cytoplasm or bound to the endoplasmic reticulum (ER) to form rough ER. In a mammalian cell there can be as many as 10 million ribosomes. Several ribosomes can be attached to the same mRNA strand, this structure is called a polysome. Ribosomes have only a temporary existence.
Free ribosomes are located in the cytoplasm of the cell. They are not attached to any structure, but they may group together with other ribosomes to form polysomes. In the cytoplasm, ribosomes are free floating. They can move all around the cell. Bound ribosomes are located on the surface of the endoplasmic reticulum. The endoplasmic reticulum that contains ribosomes is described as the rough endoplasmic reticulum because of the bumpy surface.