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Lung function will also be affected by, or co-vary, with other factors, such as smoking and chronic respiratory diseases. However, the relationships between these variables are not always obvious as some smokers never develop symptoms and lung function decline, while some never smokers become ill, etc [1, 2].
Thereforeas the lung increases in size, more pressure must be applied to get the same increase in volume. This can be seen from the following pressure-volume curve of the lung: Lung compliance and the slope are the same: Compliance can also change in various disease states. For example, in fibrosis the lungs become stiff, making a large pressure necessary to maintain a moderate volume.