Research has demonstrated that many individuals with Crohnâs ileitis share a genetic mutation that may play a significant role in disease development. A hypersensitive immuno-response to a pathogenic presence, such as bacteria, within the gastrointestinal tract is also suspected of contributing to the disease's onset.
Secondary osteoarthritis occurs less frequently than primary (also known as idiopathic) osteoarthritis. Primary osteoarthritis means that there is no known cause for the joint breakdown.
1 Osteoarthritis is a joint inflammation that results from cartilage degeneration. 2  Osteoarthritis can be caused by aging, heredity, and injury from trauma or disease. 3  The most common symptom of osteoarthritis is pain in the affected joint(s) after repetitive use. 4  There is no blood test for the diagnosis of osteoarthritis.steoarthritis is abbreviated as OA or referred to as degenerative arthritis or degenerative joint disease (DJD). Osteoarthritis commonly affects the hands, feet, spine, and large weight-bearing joints, such as the hips and knees.