Research has demonstrated that many individuals with Crohnâs ileitis share a genetic mutation that may play a significant role in disease development. A hypersensitive immuno-response to a pathogenic presence, such as bacteria, within the gastrointestinal tract is also suspected of contributing to the disease's onset.
Secondary osteoarthritis occurs less frequently than primary (also known as idiopathic) osteoarthritis. Primary osteoarthritis means that there is no known cause for the joint breakdown.
Osteoarthritis of the hip joints is commonly related to design abnormalities of these joints that had been present since birth. Hormone disturbances, such as diabetes and growth hormone disorders, are also associated with early cartilage wear and secondary osteoarthritis.