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Inflammation may result in organ damage. Blood clotting during sepsis reduces blood flow to limbs and internal organs, depriving them of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, infection leads to a life-threatening drop in blood pressure, called septic shock.
While we still donât know why our bodies react this way, we know that sepsis can cause: 1  Leakage from the lining blood vessel linings (much like a water hose with holes in it) 2  Low blood pressure (hypotension) with reduced blood flow to vital organs. 3  Small clots throughout the body that prevent nutrients from reaching vital organs.