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Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.roduction of T 3 and its prohormone thyroxine (T 4) is activated by thyroid-stimulating hormone (TSH), which is released from the pituitary gland. This pathway is part of a closed-loop feedback process: Elevated concentrations of T 3, and T 4 in the blood plasma inhibit the production of TSH in the pituitary gland.