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3. Low serum chloride suggests an electrolyte derangement. 4. Low anti-nuclear antibodies: Anti-nuclear antibodies are raised in connective tissue disorders eg systemic lupus erythematosus. However, a negative value rules out this possibility.
A low serum osmolality would be indicative of a higher than usual amount of water in relation to the amount of particles dissolved in it. It would be expected, then, that a low serum osmolality would accompany overhydration, or edema, and an increased serum osmolality would be present in a state of fluid volume deficit.