1 702.12b A permanent with indestructible canât be destroyed. 2  Such permanents arenât destroyed by lethal damage, and they ignore the state-based action that checks for lethal damage (see rule 704.5g). 3  702.12c Multiple instances of indestructible on the same permanent are redundant.
lethal dose. n. (Pharmacology) the amount of a drug or other agent that if administered to an animal or human will prove fatal.
Nicotine Toxicology. By Dr Ananya Mandal, MD. Nicotine is a highly toxic chemical. While in rats, a dose of 50 mg per kg is lethal, in mice the median lethal dose is around 3 mg per kg weight. In humans, the median lethal dose is 0.5 to 1.0 mg/kg or around 40 to 60 mg in an average human. This low lethal dose makes nicotine more toxic than many other compounds including even alkaloids such as cocaine which has a median lethal dose of 95.1 mg per kg in mice.