The main stem of the Bay itself is about 189 miles (304 km) long, from the Susquehanna River in the north to the Atlantic Ocean in the south. At its narrowest point near Annapolis, Maryland, the Bay is 4 miles (6.4 km) wide; at its widest point, near the mouth of the Potomac River, it is 30 miles (50 km) wide.
Patau syndrome. Patau syndrome is a syndrome caused by a chromosomal abnormality, in which some or all of the cells of the body contain extra genetic material from chromosome 13. The extra genetic material disrupts normal development, causing multiple and complex organ defects.
It is caused by an abnormal amyloid transthyretin (TTR) protein, which is made in the liver. This protein is responsible for the most common forms of hereditary amyloidosis. Senile systemic amyloidosis (SSA). This is caused deposits of normal TTR in the heart and other tissues.