What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
Rose bushes (Rosa spp.) must be pruned at least once or twice each year. Heavy pruning is done in winter or, in some climates, early spring. Roses are hardy in U.S. Department of Agriculture plant hardiness zones 2 through 11, depending on the species.Prune the roses again in summer or fall right after they bloom to tidy them up and encourage new cane growth.Roses that produce flowers in spring and again in fall bloom more profusely in fall when pruned right after their spring bloom cycle.ose bushes (Rosa spp.) must be pruned at least once or twice each year. Heavy pruning is done in winter or, in some climates, early spring. Roses are hardy in U.S. Department of Agriculture plant hardiness zones 2 through 11, depending on the species.