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The most common Topamax side effects when taken with other medicines by children with epilepsy are: 1  Fatigue. 2  Sleepiness. 3  Lack of appetite (anorexia) 4  Nervousness. Problems concentrating or paying attention.  Memory 1  problems. Aggressiveness.  Weight loss.
Factors that influence weight loss on Topamax. There are other factors that may influence weight fluctuation as a result of Topamax treatment. These include things like: the dosage you ware taking, time span over which youâve been taking it, your lifestyle and general habits, genetics, as well as other medications that you take.