What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
2. Prune branches all over the Knock Out rose bush in late winter, after buds have formed and are coming out of their dormant winter state. Cut back new growth to bring branches back into line or reduce the size of the bush.You must prune before new growth appears. Snip branches at a 45-degree angle to promote growth.nap off dead blooms from Knock Out roses after budding to encourage new blooms. Knock Out roses self-dead head, which means they drop dead blooms eventually, allowing new flowers to form. However, they tend to take a while to drop, so doing it yourself can speed up the process and make the bushes look more appealing.