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Antimicrobial susceptibility testing. Determine vancomycin resistance as well as high-level resistance to penicillin and. aminoglycosides for enterococci isolated from blood, sterile body sites (with the. possible exception of urine), and other sites as clinically indicated. Evaluate the.
Vancomycin trough concentrations below 10 Âµg/mL are associated with inadequate therapy and an increased risk of developing bacterial resistance. Vancomycin trough concentrations above the therapeutic range may increase the risk of nephrotoxicity.