If you experience chronic constipation, or if eating prunes and drinking prune juice doesnât solve your problems, contact your doctor for professional advice. Also, make sure to talk to your doctor if you begin to experience: 1  rectal or abdominal pain.  blood in stool.
agonist agÂ·oÂ·nist (Äg'É-nÄ­st) n. A contracting muscle that is resisted or counteracted by an antagonistic muscle. A substance that can combine with a cell receptor to produce a reaction typical for that substance.
An inverse agonist is an agent that binds to the same receptor binding-site as an agonist for that receptor and inhibits the constitutive activity of the receptor. Inverse agonists exert the opposite pharmacological effect of a receptor agonist, not merely an absence of the agonist effect as seen with antagonist.An example is the cannabinoid inverse agonist rimonabant. A co-agonist works with other co-agonists to produce the desired effect together.nverse agonists exert the opposite pharmacological effect of a receptor agonist, not merely an absence of the agonist effect as seen with antagonist. An example is the cannabinoid inverse agonist rimonabant. A co-agonist works with other co-agonists to produce the desired effect together.