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Vesicoureteral reflux (VUR) is characterized by the retrograde flow of urine from the bladder to the kidneys. VUR may be associated with urinary tract infection (UTI), hydronephrosis, and abnormal kidney development (renal dysplasia).
What is the significance of reflux? Reflux alone does not usually cause a problem unless there is blockage of urine flow in the urinary tract. The problem with reflux is that if an infection (UTI) starts in the bladder, it may easily ascend to the kidney, leading to a kidney infection.