What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
In general, you will be pruning just before the plant breaks dormancy after spring's final frost. This will be early in the year in warm climates, and anytime between January and April in cold climates. If it's old roses you are tending, prune them after blooming. They bear flowers on last year's wood. Cut away the dead wood first -- it will help you see the shape of the plant without distraction. It's a good idea to visit a public rose garden and find specimens of roses you are growing. Note how the gardeners have pruned roses of the same type.