What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
Original Knock Out rose. 1  Long Blooming: Knock Out roses start blooming in spring and keep it up full tilt until well into fall. 2  Disease Resistant: Knock Out roses are resistant to black spot and other diseases.  Shade Tolerant: While roses are usually full-sun plants, Knock Out roses will tolerate some partial shade.