If you experience chronic constipation, or if eating prunes and drinking prune juice doesnât solve your problems, contact your doctor for professional advice. Also, make sure to talk to your doctor if you begin to experience: 1  rectal or abdominal pain.  blood in stool.
agonist agÂ·oÂ·nist (Äg'É-nÄ­st) n. A contracting muscle that is resisted or counteracted by an antagonistic muscle. A substance that can combine with a cell receptor to produce a reaction typical for that substance.
A prerequisite for an inverse agonist response is that the receptor must have a constitutive (also known as intrinsic or basal) level activity in the absence of any ligand. An agonist increases the activity of a receptor above its basal level, whereas an inverse agonist decreases the activity below the basal level.A neutral antagonist has no activity in the absence of an agonist or inverse agonist but can block the activity of either.The efficacy.n agonist increases the activity of a receptor above its basal level, whereas an inverse agonist decreases the activity below the basal level. A neutral antagonist has no activity in the absence of an agonist or inverse agonist but can block the activity of either. The efficacy.