One of Pavlov's dogs, preserved at The Pavlov Museum, Ryazan, Russia. The concept for which Pavlov is famous is the  conditioned reflex  (or in his own words the conditional reflex) he developed jointly with his assistant Ivan Filippovitch Tolochinov in 1901. He had come to learn this concept of conditioned reflex when examining the rates of salivations among dogs.
There are 110 calories in 1 large Honeycrisp Apple. Calorie breakdown: 3% fat, 96% carbs, 2% protein.
An apple contains less than 200 calories. This leaves a lot of room for eating considering the amount of calories recommended by daily calorie intakes. That is why it is said that going on a 3 day apple diet cleanse will not only flush your system but help you lose weight as well. In a 100g serving size there are only 54 calories in apples.