914-765-0688. 1  Beehive Restaurant, serving Traditional American with a few Mediterranean dishes, is located at 30 Old Route 22, Armonk, NY 10504 in Westchester County. 2  The Cafe at Mariani Gardens is located at 45 Bedford Road in Armonk, NY 10504 in Westchester County.
The Discovery of the lac Operon. In 1961, Francois Jacob and Jacques Monod proposed the operon model of gene regulation in bacteria. The model was based on their study of the genes in E. coli that code for enzymes that affect the breakdown of lactose. Francois Jacob and Jacques Monod. Photo courtesy of Archive Photo. Because of the pioneering work of Jacob and Monod, the lac operon is typically used to illustrate gene regulation in bacteria.
In the absence of lactose the lac repressor blocks the expression of the lac operon by binding to the DNA at a site, called the operator that is downstream of the promoter and upstream of the transcriptional initiation site.he protein that inhibits transcription of the lac operon is a tetramer with four identical subunits called lac repressor. The lac repressor is encoded by the lacI gene, located upstream of the lac operon and has its own promoter.