What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
The Knock Out series of roses is a group of hybrid shrub roses introduced by the Conard-Pyle rose company, beginning in 2000 with the original red-flowered variety, Knock Out. The series has now expanded to seven rose varieties. The majority of Knock Out roses are sold in containers, ready to plant. They can be installed in the garden any time after the last spring frost, but special precautions should be taken if you are planting during the hottest part of summer when climate conditions put added stress on the plant.