When you apply the brakes, brake fluid is forced under pressure into the wheel cylinder, which in turn pushes the brake shoes into contact with the machined surface on the inside of the drum. When the pressure is released, return springs pull the shoes back to their rest position.
Normally, protein is not removed when the kidneys filter waste from the blood. However, when the kidneys are damaged, protein leaks through the damaged filters and is removed from the body in the urine, along with the waste products.
Damaged kidneys fail to regulate blood pressure. Healthy kidneys produce a hormone called aldosterone to help the body regulate blood pressure. Kidney damage and uncontrolled high blood pressure each contribute to a negative spiral. As more arteries become blocked and stop functioning, the kidneys eventually fail.