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The most common Topamax side effects when taken with other medicines by children with epilepsy are: 1  Fatigue. 2  Sleepiness. 3  Lack of appetite (anorexia) 4  Nervousness. Problems concentrating or paying attention.  Memory 1  problems. Aggressiveness.  Weight loss.
topamax, migraine, headache, pain. Details: My doctor put me on Topamax for Migraine headaches at the end of January. I started out on the 25mg dose with no problems, but when I stepped up my dose to 50mgs, I began to have chest pains. Since then, my doctor has taken me off this drug. I am a little disappointed, because it was working wonderfully.