Although aminoglycoside-induced nephrotoxicity is generally reversible following discontinuation of the drug, death from uremia has occurred rarely. Therapy with aminoglycosides should be administered cautiously at reduced dosages in patients with renal impairment, since they may be at increased risk for oto- and nephrotoxicity due to drug accumulation.
â Paul Wesley. Paul Thomas Wesley (Polish: PaweÅ Tomasz Wasilewski, born July 23, 1982) is a Polish-American actor who plays Stefan Salvatore, Tom Avery, Silas and Ambrose on The Vampire Diaries. He appeared on several TV shows such as The Guiding Light, Wolf Lake, Smallville, and Everwood.
Paul is thought to have died in Rome as a martyr. The New Testament book of Acts 26 tells of Paul standing trial before the Roman Procurators Felix and then Festus.This information is used to suggest a date of about 59 AD. well-known tradition is that Paul was beheaded. The evidence available suggests that Paul died a martyr in Rome in about the mid-60s AD. That he died in Rome is the most certain, the exact date and manner of his death are more questionable.