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3. Low serum chloride suggests an electrolyte derangement. 4. Low anti-nuclear antibodies: Anti-nuclear antibodies are raised in connective tissue disorders eg systemic lupus erythematosus. However, a negative value rules out this possibility.
Chloride is one of the four major electrolytes found in the body. Chloride is one of the four main electrolytes found in the serum, or bloodstream. Serum electrolytes, such as sodium, potassium, bicarbonate, and chloride, are important for maintaining the human body's delicate fluid and metabolic acid-base balance.