Definition of Speech Impairment. A speech impairment is a condition in which the ability to produce speech sounds that are necessary to communicate with others is impaired. Speech impairments can be mild, such as occasionally mispronouncing a couple of words, to severe, such as not being able to produce speech sounds at all.
methotrexate (Oral route) Only use for life-threatening neoplastic disease or severe rheumatoid arthritis and psoriasis unresponsive to other therapies. Death, fetal death and/or congenital anomalies, lung disease, tumor lysis syndrome, fatal skin reactions, and Pneumocystis carinii pneumonia have been reported.
Doctors usually first prescribe methotrexate to treat rheumatoid arthritis. If that alone doesnât calm the inflammation, doctors may try or add a different type of DMARD. Other DMARDs include hydroxychloroquine (Plaquenil), leflunomide (Arava) and sulfasalazine (Azulfidine).