Research has demonstrated that many individuals with Crohnâs ileitis share a genetic mutation that may play a significant role in disease development. A hypersensitive immuno-response to a pathogenic presence, such as bacteria, within the gastrointestinal tract is also suspected of contributing to the disease's onset.
Secondary osteoarthritis occurs less frequently than primary (also known as idiopathic) osteoarthritis. Primary osteoarthritis means that there is no known cause for the joint breakdown.
Osteoarthritis is a form of arthritis that features the breakdown and eventual loss of the cartilage of one or more joints. Cartilage is a protein substance that serves as a cushion between the bones of the joints. Among the over 100 different types of arthritis conditions, osteoarthritis is the most common. Osteoarthritis is a joint inflammation that results from cartilage degeneration. 2  Osteoarthritis can be caused by aging, heredity, and injury from trauma or disease. 3  The most common symptom of osteoarthritis is pain in the affected joint(s) after repetitive use. 4  There is no blood test for the diagnosis of osteoarthritis.