One of Pavlov's dogs, preserved at The Pavlov Museum, Ryazan, Russia. The concept for which Pavlov is famous is the  conditioned reflex  (or in his own words the conditional reflex) he developed jointly with his assistant Ivan Filippovitch Tolochinov in 1901. He had come to learn this concept of conditioned reflex when examining the rates of salivations among dogs.
There are 110 calories in 1 large Honeycrisp Apple. Calorie breakdown: 3% fat, 96% carbs, 2% protein.
One large apple has about 116 calories in it.Apples also contain  vitamins and fiber and are a member of the rose family.