Serial lactate measures also help assess response to therapy. The half-life of lactate is around 20 minutes, even in septic patients. If the lactate is persistently elevated, it's not because the body can't get rid of it, but because the body continues producing it, shifting to anaerobic metabolism.
That's because the Philadelphia Rock 'n' Roll Half Marathon, which has been run in the city for 38 years, has a new date for 2015, landing on Oct. 31.
Some 35,000 athletes will begin their gruelling 26.2 mile journey at 10.10am on Sunday when the London Marathon mass event gets underway. Charity runners will begin the course at three different start points in Greenwich Park and Blackheath, south London, before the routes converge just before the three-mile mark.