Although aminoglycoside-induced nephrotoxicity is generally reversible following discontinuation of the drug, death from uremia has occurred rarely. Therapy with aminoglycosides should be administered cautiously at reduced dosages in patients with renal impairment, since they may be at increased risk for oto- and nephrotoxicity due to drug accumulation.
â Paul Wesley. Paul Thomas Wesley (Polish: PaweÅ Tomasz Wasilewski, born July 23, 1982) is a Polish-American actor who plays Stefan Salvatore, Tom Avery, Silas and Ambrose on The Vampire Diaries. He appeared on several TV shows such as The Guiding Light, Wolf Lake, Smallville, and Everwood.
Paul Revere was an American silversmith, engraver, early industrialist, and Patriot in the American Revolution. He is best known for his midnight ride to alert the colonial militia in April 1775 to the approach of British forces before the battles of Lexington and Concord, as dramatized in Henry Wadsworth Longfellow's poem, Paul Revere's Ride. At age 41, Revere was a prosperous, established and prominent Boston silversmith. He had helped organize an intelligence and alarm system to keep watch