Carthage again went to war with Rome when the general Hannibal attacked the city of Saguntum. Following this war, Carthage became embroiled in what is known as The Mercenary War (241-237 BCE) which started when the Carthaginian army of mercenaries demanded the payment Carthage owed them.
The cause of dermatofibrosarcoma protuberans (DFSP) is unknown. Laboratory studies have shown that chromosomal aberrations may contribute to the pathogenesis of DFSP; however, no evidence of hereditary or familial predisposition exists. In 10-20% of patients with this tumor, trauma at the site seems to be incriminated.
Definition of Hereditary mixed polyposis syndrome. Hereditary mixed polyposis syndrome: (HMPS) A cancer family syndrome characterized by the development of a variety of different types of polyps in the colon, including atypical juvenile polyps and adenomas of the colon, and by the development of colorectal carcinoma (cancer of colon and rectum). HMPS is inherited in an autosomal dominant manner. The HMPS gene locus is on chromosome 15 in region 15q13-q14. HMPS is also known as colorectal adenoma and carcinoma 1 (CRAC1). It has been uncertain whether HMPS is a distinct disorder or a variant of an established disease called juvenile polyposis.