Vancouver has recently experienced conflicts with other Clark County communities because of rapid growth in the area. The city's first annexation more than doubled its size in 1909, with the largest annexation of 1997 adding 11,258 acres (45.56 km 2) and 58,171 residents.
Why is nicotine addictive? When you use tobacco products, nicotine is quickly absorbed into your bloodstream. Within 10 seconds of entering your body, the nicotine reaches your brain. It causes the brain to release adrenaline, creating a buzz of pleasure and energy. The buzz fades quickly though, and leaves you feeling tired, a little down, and wanting the buzz again. This feeling is what makes you light up the next cigarette.
Nicotine imitates the action of a natural neurotransmitter called acetylcholine and binds to a particular type of acetylcholine receptor, known as the nicotinic receptor. Whether it is acetylcholine or nicotine that binds to this receptor, it responds in the same way: it changes its conformation, which causes its associated ion channel to open for a few milliseconds.