What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
Climbing roses are best winterized by removing the canes from the fence or trellis, laying them on the ground, and allowing snow cover to protect them from extreme cold. If you cannot count on continuous snow cover during the winter, you can mound soil or mulch over the canes on the ground.