Definition of Speech Impairment. A speech impairment is a condition in which the ability to produce speech sounds that are necessary to communicate with others is impaired. Speech impairments can be mild, such as occasionally mispronouncing a couple of words, to severe, such as not being able to produce speech sounds at all.
methotrexate (Oral route) Only use for life-threatening neoplastic disease or severe rheumatoid arthritis and psoriasis unresponsive to other therapies. Death, fetal death and/or congenital anomalies, lung disease, tumor lysis syndrome, fatal skin reactions, and Pneumocystis carinii pneumonia have been reported.
Tell your dentist or doctor that you are taking methotrexate before you have a surgical procedure. 1  Methotrexate is a medicine that comes from folic acid and is called an antimetabolite. Methotrexate is given to patients to treat a number of medical conditions, including a skin condition called psoriasis. It is also given to patients to treat rheumatoid arthritis and certain types of cancers.