One of Pavlov's dogs, preserved at The Pavlov Museum, Ryazan, Russia. The concept for which Pavlov is famous is the  conditioned reflex  (or in his own words the conditional reflex) he developed jointly with his assistant Ivan Filippovitch Tolochinov in 1901. He had come to learn this concept of conditioned reflex when examining the rates of salivations among dogs.
There are 110 calories in 1 large Honeycrisp Apple. Calorie breakdown: 3% fat, 96% carbs, 2% protein.
Overall, it is broken down very easily, leading to a big surge in blood glucose. One tablespoon of sugar yields about 49 calories and about 15 grams of carbohydrate. Honey is also mostly sugar, but is only about 30 percent glucose and less than 40 percent fructose. Unlike sugar, these are typically found in the free form, meaning honey is digested a little differently than white sugar.