In the normal state, blood has no business anywhere except in the confines of the heart and blood vessels and in the sinusoids of the marrow, liver, and spleen. Of the average 5 L of blood, only 2.25 L, or 45%, consists of cells.
Take-away: Calcium and magnesium may best be taken in the evening with food or before nighttime sleep. Since zinc should not be taken with calcium and apart from iron, it is most useful if taken earlier in the day either slightly before/after food. Iron should ideally be taken on an empty stomach and separately from other multivitamin/multimineral combinations.
1 Acne. 2  Osteoporosis. 3  Low zinc intake seems to be linked to lower bone mass. 4  Taking a zinc supplement in combination with copper, manganese, and calcium might also decrease bone loss in postmenopausal women. 5  Treating an inherited disorder called acrodermatitis enteropathica. 6  Leprosy, when used with other medications.