Kuali Financial System. Become a KFS User. Make sure you have an Acceptable Use Agreement on file. If you have not completed one before, you can do so at: http://protect.iu.edu/agreement. Your department must submit a KFS System User Role document, located in the Chart of Accounts module of KFS.
A change in. the content of the genetic messageâthe base sequence of. one or more genesâis referred to as a mutation. Some mu-. tations alter the identity of a particular nucleotide, while. others remove or add nucleotides to a gene.
As mentioned, sickle-cell anemia is the result of a change in a single nucleotide, and it represents just one class of mutations called point mutations. Changes in the DNA sequence can also occur at the level of the chromosome, in which large segments of chromosomes are altered.s mentioned, sickle-cell anemia is the result of a change in a single nucleotide, and it represents just one class of mutations called point mutations. Changes in the DNA sequence can also occur at the level of the chromosome, in which large segments of chromosomes are altered.