Stoic temperament: Because many of the biggest breeds were bred to be guard dogs, many are the strong, silent type. Slobbery kisses: Many of the biggest breeds are closely related to the Mastiff, one of the original dog types with saggy lips and lots of slobber.
IOP (intraocular pressure): The pressure created by the continual renewal of fluids within the eye. The normal IOP varies among individuals. The intraocular pressure is increased in glaucoma. In acute angle-closure glaucoma, the intraocular pressure rises rapidly because the iris blocks the angle in the front of the eye where the anterior chamber fluid normally drains out.
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