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4. Synonym: trisomy 13. Patau's syndrome (trisomy 13) carries a high mortality rate with multiple congenital abnormalities which result in severe physical and mental impairment. 1  It is usually due to a free-standing trisomy with an extra number 13 chromosome, instead of the usual pair, in all cells.
References. 1  1. Bluestone CD et al. Management of the patulous Eustachian tube. 2  2. Cairns W. The patulous Eustachian tube syndrome. Palliat Med. 3  3. Kuppersmith RB. Eustachian tube Function and Dysfunction. 4  4. Ng SK and CA van Hasselt. Patulous Eustachian tube. 5  5. Doherty JK, et al. Autologous Fat Grafting for the Refractory Patulous Eustachian Tube.