Meta analyses are only as good as the quality of the underlying studies, which in this case is not very good. Some studies published in quality journals suggest that berberine's positive effects may stem from the fact that it activates AMP-Kinase, which is what metformin does.
Figure 34-2 Medial thigh furrow (wide line) is surface depression extending from proximal anterior to distal posterior thigh. Furrow divides area into medial thigh (proximal) and medial knee (distal). Figure 34-3 Full view of medial thigh/knee contour drawings. A, Right medial thigh, with patient standing and raising left thigh. This view demonstrates medial thigh furrow. B, Left medial thigh, with patient standing and raising right thigh.
The iliolumbar ligaments extend from the posterior iliac crest to the transverse processes of L4 or L5 and secure the pelvis to the lumbar spine (10,12,13). 1  The posterior SI ligament is a key vertical stabilizer, maintaining the sacrum in its normal position in the pelvic ring (14).