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Vesicoureteral reflux (VUR) is characterized by the retrograde flow of urine from the bladder to the kidneys. VUR may be associated with urinary tract infection (UTI), hydronephrosis, and abnormal kidney development (renal dysplasia).
The main cause of acid reflux disease is a problem with the lower esophageal sphincter (LES) muscle. This muscle, which is the âvalveâ between the stomach and the esophagus, normally closes tightly after food has passed through to the stomach. The LES does not stay closed in people with acid reflux disease.