Research in knockout mice has demonstrated that Aire functions through initiating the transcription of a diverse set of self-antigens, such as insulin, in the thymus. This expression then allows maturing thymocytes to become tolerant towards peripheral organs, thereby suppressing autoimmune disease.he autoimmune regulator is mutated in the rare autoimmune syndrome Autoimmune Polyendocrinopathy Syndrome type 1 (APS-1), also known as Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED).
Although your white blood cells account for only about 1 percent of your blood, their impact is significant. White blood cells, also called leukocytes, are essential for good health and protection against illness and disease. Think of white blood cells as your immunity cells.
Which term means the percentage of total blood volume composed of red blood cells? The hematocrit percentage is the red blood cell percentage per total blood volume. About 40% t0 46% in health males. 36% to 40% in healthy females.Varies in age and hea â¦ lth conditions.1 person found this useful.ematocrit The hematocrit is the percentage of red blood cells by volume. A hematocrit is the term that describes the percentage by volume of a blood sample occupied by red bl â¦ ood cells. It is usually about 45%. Hematocrit.