914-765-0688. 1  Beehive Restaurant, serving Traditional American with a few Mediterranean dishes, is located at 30 Old Route 22, Armonk, NY 10504 in Westchester County. 2  The Cafe at Mariani Gardens is located at 45 Bedford Road in Armonk, NY 10504 in Westchester County.
The Discovery of the lac Operon. In 1961, Francois Jacob and Jacques Monod proposed the operon model of gene regulation in bacteria. The model was based on their study of the genes in E. coli that code for enzymes that affect the breakdown of lactose. Francois Jacob and Jacques Monod. Photo courtesy of Archive Photo. Because of the pioneering work of Jacob and Monod, the lac operon is typically used to illustrate gene regulation in bacteria.
Bacterial operons are polycistronic transcripts that are able to produce multiple proteins from one mRNA transcript. In this case, when lactose is required as a sugar source for the bacterium, the three genes of the lac operon can be expressed and their subsequent proteins translated: lacZ, lacY, and lacA.The gene product of lacZ is Î²-galactosidase which cleaves lactose, a disaccharide, into glucose and galactose.he protein that is formed by the lacI gene is known as the lac repressor. The type of regulation that the lac operon undergoes is referred to as negative inducible, meaning that the gene is turned off by the regulatory factor (lac repressor) unless some molecule (lactose) is added.