Definition of Speech Impairment. A speech impairment is a condition in which the ability to produce speech sounds that are necessary to communicate with others is impaired. Speech impairments can be mild, such as occasionally mispronouncing a couple of words, to severe, such as not being able to produce speech sounds at all.
methotrexate (Oral route) Only use for life-threatening neoplastic disease or severe rheumatoid arthritis and psoriasis unresponsive to other therapies. Death, fetal death and/or congenital anomalies, lung disease, tumor lysis syndrome, fatal skin reactions, and Pneumocystis carinii pneumonia have been reported.
1 Methotrexate can be taken by mouth (tablets) or by injection as follows: 2  Tablets: Methotrexate is available in 2.5 mg tablets. 3  The standard dose ranges from 6 tablets per week (15 mg) to 10 tablets per week (25 mg).4  Injection: Methotrexate is available in a liquid (25 mg/mL) for injection. Injection: Methotrexate is available in a liquid (25 mg/mL) for injection. 2  The standard dose ranges from 0.6 mL (15 mg) to 1.0 mL (25 mg) per week.