In the normal state, blood has no business anywhere except in the confines of the heart and blood vessels and in the sinusoids of the marrow, liver, and spleen. Of the average 5 L of blood, only 2.25 L, or 45%, consists of cells.
Take-away: Calcium and magnesium may best be taken in the evening with food or before nighttime sleep. Since zinc should not be taken with calcium and apart from iron, it is most useful if taken earlier in the day either slightly before/after food. Iron should ideally be taken on an empty stomach and separately from other multivitamin/multimineral combinations.
Consumers are now being advised to switch to a zinc-free denture adhesive and there is information on those options below as well as information on the symptoms of having too much zinc or not enough copper in the body. Partial list of symptoms of zinc poisoning or copper deficiency: Problems with balance.