Definition of Speech Impairment. A speech impairment is a condition in which the ability to produce speech sounds that are necessary to communicate with others is impaired. Speech impairments can be mild, such as occasionally mispronouncing a couple of words, to severe, such as not being able to produce speech sounds at all.
methotrexate (Oral route) Only use for life-threatening neoplastic disease or severe rheumatoid arthritis and psoriasis unresponsive to other therapies. Death, fetal death and/or congenital anomalies, lung disease, tumor lysis syndrome, fatal skin reactions, and Pneumocystis carinii pneumonia have been reported.
This medication may be given as a tablet taken by mouth, an injection into a vein (intravenous), or an injection into a muscle (intramuscular). Intravenous injections usually take up to 20 minutes. Sometimes, methotrexate may be injected into the spinal cord in order to kill cancer cells in that region. The exact approach, dose, and schedule varies depending on the type of cancer being treated, the extent of disease, and other factors.