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Antibiotics for Ear Infections: An Overview Many antibiotics are approved by the Food and Drug Administration (FDA) to fight otitis media (ear infections), although most doctors rely on a few favorites. Most antibiotics for ear infections fall under four families:  penicillins, cephalosporins, sulfonamides, and erythromycins. Amoxicillin is the most common antibiotic used to treat ear infections. When using antibiotics for ear infections, remember to take each dose on schedule.
The second thing to think about is the type of ear drop you're using, as there are many different varieties. Some ear drops are actual antibiotics and treat infections in the ear canal. Antibiotic ear drops require a prescription from a doctor.There are ear drops that just help relieve ear pain topically. Such ear drops may be helpful, although scientific studies have not proven that such drops are very effective.he second thing to think about is the type of ear drop you're using, as there are many different varieties. Some ear drops are actual antibiotics and treat infections in the ear canal. Antibiotic ear drops require a prescription from a doctor.