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Inflammation may result in organ damage. Blood clotting during sepsis reduces blood flow to limbs and internal organs, depriving them of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, infection leads to a life-threatening drop in blood pressure, called septic shock.
Sepsis Symptoms. Because sepsis can begin in different parts of the body, it can have many different symptoms. Rapid breathing and a change in mental status, such as reduced alertness or confusion, may be the first signs that sepsis is starting.Other common symptoms include: 1  Fever and shaking chills or, alternatively, a very low body temperature. 2  Decreased urination.3  Rapid pulse.4  Rapid breathing.apid breathing and a change in mental status, such as reduced alertness or confusion, may be the first signs that sepsis is starting. Other common symptoms include: 1  Fever and shaking chills or, alternatively, a very low body temperature. 2  Decreased urination. 3  Rapid pulse. 4  Rapid breathing.