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Inflammation may result in organ damage. Blood clotting during sepsis reduces blood flow to limbs and internal organs, depriving them of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, infection leads to a life-threatening drop in blood pressure, called septic shock.
Sepsis: The Basics. Sepsis is an extreme response to an infection. Your body sends a flood of chemicals into your bloodstream to fight the threat. This causes widespread inflammation which, over time, can slow blood flow and damage your organs.epsis: The Basics. Sepsis is an extreme response to an infection. Your body sends a flood of chemicals into your bloodstream to fight the threat. This causes widespread inflammation which, over time, can slow blood flow and damage your organs.