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Best Answer: Alcohol or ethanol affects the human nervous system by inhibiting signals between the brain, nerve endings and spinal cord. When people drink, their bloodstream absorbs the alcohol and nervous system functions slow down dramatically--this is the buzz or numbness people commonly feel after drinking.
Alcohol directly affects brain chemistry by altering levels of neurotransmitters â the chemical messengers that transmit the signals throughout the body that control thought processes, behavior and emotion. Alcohol affects both âexcitatoryâ neurotransmitters and âinhibitoryâ neurotransmitters. An example of an excitatory neurotransmitter is glutamate, which would normally increase brain activity and energy levels. Alcohol suppresses the release of glutamate, resulting in a slowdown along your brainâs highways.