Meta analyses are only as good as the quality of the underlying studies, which in this case is not very good. Some studies published in quality journals suggest that berberine's positive effects may stem from the fact that it activates AMP-Kinase, which is what metformin does.
Figure 34-2 Medial thigh furrow (wide line) is surface depression extending from proximal anterior to distal posterior thigh. Furrow divides area into medial thigh (proximal) and medial knee (distal). Figure 34-3 Full view of medial thigh/knee contour drawings. A, Right medial thigh, with patient standing and raising left thigh. This view demonstrates medial thigh furrow. B, Left medial thigh, with patient standing and raising right thigh.
Structure [edit]. Sulci are one of three parts of the cerebral cortex, the others being the gyri and the fissures. The three different parts create a larger surface area for the human brain and other mammalian brains. When looking at the human brain, two-thirds of the surface is hidden in the grooves.The sulci and fissures are both grooves in the cortex but they are differentiated by size. A sulcus is a shallower groove that surrounds a gyrus.ulci are one of three parts of the cerebral cortex, the others being the gyri and the fissures. The three different parts create a larger surface area for the human brain and other mammalian brains.