Although aminoglycoside-induced nephrotoxicity is generally reversible following discontinuation of the drug, death from uremia has occurred rarely. Therapy with aminoglycosides should be administered cautiously at reduced dosages in patients with renal impairment, since they may be at increased risk for oto- and nephrotoxicity due to drug accumulation.
â Paul Wesley. Paul Thomas Wesley (Polish: PaweÅ Tomasz Wasilewski, born July 23, 1982) is a Polish-American actor who plays Stefan Salvatore, Tom Avery, Silas and Ambrose on The Vampire Diaries. He appeared on several TV shows such as The Guiding Light, Wolf Lake, Smallville, and Everwood.
Paul Revere (/rÉªËvÉªÉr/ ; December 21, 1734 O.S. â May 10, 1818) was an American silversmith, engraver, early industrialist, and a patriot in the American Revolution.ecause Boston was besieged after the battles of Lexington and Concord, Revere could not return to the city, which was now firmly in British hands. He boarded in Watertown, where he was eventually joined by Rachel and most of his children (Paul Jr., then 15, remained in Boston to mind the family properties).