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calcaneofibular ligament. 1. the middle of the three fascicles that form the lateral ligament of the ankle joint, reinforcing the lateral side of the ankle joint and resisting excessive inversion of the foot; the remaining two ligaments of the lateral ligaments are the anterior and posterior talofibular ligaments.
The anterior talofibular ligament is injured first, followed by injury to the calcaneofibular ligament and posterior talofibular ligament. Since the anterior talofibular ligament is the weakest ligament in the lateral ankle complex, it is most commonly injured as a result of plantarflexion and inversion injuries.