Carthage again went to war with Rome when the general Hannibal attacked the city of Saguntum. Following this war, Carthage became embroiled in what is known as The Mercenary War (241-237 BCE) which started when the Carthaginian army of mercenaries demanded the payment Carthage owed them.
The cause of dermatofibrosarcoma protuberans (DFSP) is unknown. Laboratory studies have shown that chromosomal aberrations may contribute to the pathogenesis of DFSP; however, no evidence of hereditary or familial predisposition exists. In 10-20% of patients with this tumor, trauma at the site seems to be incriminated.
Dermatofibrosarcoma Protuberans (DFSP) Dermatofibrosarcoma Protuberans (DFSP) is a tumor of the skin. It is a rare type of sarcoma with low-to-intermediate grade malignancy. It compromises less than 0.1% of all cancers and about 1% of all soft tissue sarcomas. DFSP tumors occur in the dermis layer of the skin and can invade deeper subcutaneous tissue, such as fat, fascia, and muscle.