What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
September is the time to act. Roses should be pruned or groomed during the first 2 weeks in September--no later than September 20. Fall pruning is lighter than in the spring. Cut about 1/4 - 1/3 of the bush. When pruning miniatures, other than cleaning them out, simply cut off all the blooms.