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Several vaccines are available to help prevent disease caused by Borrelia burgdorferi, the Lyme disease organism. An initial vaccination is followed by a booster vaccine 2 to 4 weeks later (in accordance with label recommendations) and annual boosters as long as the risk for disease exposure remains. Even dogs that receive year-round tick control products and donât spend a lot of time outside may be at risk for exposure to tick-borne diseases. 2  The Lyme disease vaccine helps prevent disease caused by Borrelia burgdorferi, the Lyme disease organism.
Several different antibiotics are listed for use in treating Lyme disease, but doxycycline and amoxicillin are two that are commonly used. Most dogs show improvement within 24 to 48 hours of starting treatment. The duration of antibiotic treatment can vary, but most dogs are treated for 30 days.