One of Pavlov's dogs, preserved at The Pavlov Museum, Ryazan, Russia. The concept for which Pavlov is famous is the  conditioned reflex  (or in his own words the conditional reflex) he developed jointly with his assistant Ivan Filippovitch Tolochinov in 1901. He had come to learn this concept of conditioned reflex when examining the rates of salivations among dogs.
There are 110 calories in 1 large Honeycrisp Apple. Calorie breakdown: 3% fat, 96% carbs, 2% protein.
Providing 64 calories in a typical serving of one tablespoon (15 ml) equivalent to 1272 kj per 100 g, honey has no significant nutritional value. Honey is generally safe, but may have various, potential adverse effects or interactions with excessive consumption, existing disease conditions, or drugs.