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Making the world better, one answer at a time. Zyrtec (cetirizine) is classified as a second generation antihistamine. It is believed to antagonize peripheral H1 receptors and not cross the blood brain barrier (this is why it is less drowsy then other antihistamines).The side effects of Zyrtec such as dry mouth may suggest that it does have some anticholinergic properties.owever, despite the claims of minimal muscarinic receptor activity, anticholinergic side effects may still occur with venlafaxine. 14 people found this useful. 1  Allergy Medications: Zyrtec Versus Claritin Zyrtec versus Claritin is more a matter of the side effects of both drugs versus their effects on allergies.
Cetirizine belongs to the second generation antihistamine class and is similar to drugs such as azelastine (Astelin), fexofenadine (Allegra), and loratadine (Claritin). Unlike other antihistamines, Zyrtec is non-sedating. It was approved by the FDA in September 1996.yrtec is considered safe to use in both children and adults, and the dosage varies depending on age and weight. For small children, Zyrtec is available in both a liquid suspension and chewable tablets. The dosage of these ranges based upon the childâs weight for children less than six years of age.