Pathogenic E. coli strains use a multi-step scheme of pathogenesis that is similar to that used by other mucosal pathogens, which consists of colonization of a mucosal site, evasion of host defences, multiplication and host damage.
Research suggests that autism can be reliably diagnosed by age 2, but this study found that fewer than half of children with autism are diagnosed by age 5. Autism is a complex neurodevelopmental disorder that affects as many as 1 in 88 U.S. children, according to the U.S. Centers for Disease Control and Prevention.
ASD can sometimes be detected at 18 months or younger. By age 2, a diagnosis by an experienced professional can be considered very reliable. However, many children do not receive a final diagnosis until much older. This delay means that children with an ASD might not get the help they need.