Definition of Speech Impairment. A speech impairment is a condition in which the ability to produce speech sounds that are necessary to communicate with others is impaired. Speech impairments can be mild, such as occasionally mispronouncing a couple of words, to severe, such as not being able to produce speech sounds at all.
methotrexate (Oral route) Only use for life-threatening neoplastic disease or severe rheumatoid arthritis and psoriasis unresponsive to other therapies. Death, fetal death and/or congenital anomalies, lung disease, tumor lysis syndrome, fatal skin reactions, and Pneumocystis carinii pneumonia have been reported.
1 Split the dose. 2  Most arthritis patients take methotrexate orally, in a dose consisting of several pills. 3  Some find that splitting the dose eases GI side effects; take half the pills in the morning and the other half 12 hours later, preferably with food. 4  Ask about medication.