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Best Answer: Alcohol or ethanol affects the human nervous system by inhibiting signals between the brain, nerve endings and spinal cord. When people drink, their bloodstream absorbs the alcohol and nervous system functions slow down dramatically--this is the buzz or numbness people commonly feel after drinking.
How does alcohol affect the brain and the rest of the body? Alcohol adversely affects the brain, the liver, the kidneys, the heart, the blood vessels, the lining of the stomach, and various hormonal and regulatory systems. Even the word intoxicated indicates alcohol's true nature - a toxic substance.