The main stem of the Bay itself is about 189 miles (304 km) long, from the Susquehanna River in the north to the Atlantic Ocean in the south. At its narrowest point near Annapolis, Maryland, the Bay is 4 miles (6.4 km) wide; at its widest point, near the mouth of the Potomac River, it is 30 miles (50 km) wide.
Patau syndrome. Patau syndrome is a syndrome caused by a chromosomal abnormality, in which some or all of the cells of the body contain extra genetic material from chromosome 13. The extra genetic material disrupts normal development, causing multiple and complex organ defects.
X-linked hypophosphatemic rickets, a dominantly inherited disease, is caused by mutations in the PHEX gene, whose function in regulating renal phosphate and vitamin D metabolism remains to be elucidated.enetic causes of rickets. Miller WL, Portale AA. Dietary deficiency of vitamin D, genetic disorders of its bioactivation to 1,25-dihydroxyvitamin D [1,25(OH)2D], or disorders of vitamin D action can cause rickets.