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The most common Topamax side effects when taken alone by adults with epilepsy are: 1  Tingling of the arms and legs. 2  Weight loss. 3  Sleepiness. A loss of appetite (anorexia) 4  Dizziness. Memory problems.
The most commonly experience side effects were nausea and tingling of the extremities. What was amazing in this trial was the effect on weight. The patients who got topiramate lost, on average, 3.8 percent of their body weight..