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3. Low serum chloride suggests an electrolyte derangement. 4. Low anti-nuclear antibodies: Anti-nuclear antibodies are raised in connective tissue disorders eg systemic lupus erythematosus. However, a negative value rules out this possibility.
Chloride (Cl) Guide. A chloride test measures the level of chloride in your blood or urine. Chloride is one of the most important electrolytes in the blood. It helps keep the amount of fluid inside and outside of your cells in balance. It also helps maintain proper blood volume, blood pressure, and pH of your body fluids.