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The most common Topamax side effects when taken alone by children aged 10 to 16 with epilepsy are: 1  Weight loss. 2  Upper respiratory tract infection. 3  Tingling of the arms and legs.  A loss of appetite 1  (anorexia) Diarrhea.  Mood problems.
High creatinine count will occur. Besides, it has been reported that taking topamax can increase the risk of forming stones in the kidneys and bladder. Though kidney stone is in most cases benign, it can cause very discomfortable pains and symptoms to the patients or even lead to renal failure.Therefore it is recommended that more fluid should be taken while having topamax to decrease the chance of getting kidney stones.opamax is a widely used antiepileptic drugs to treat epilepsy, migraine, aura, headache. Long term intake of topamax can cause some side effects such as nausea, fatigue, depression or even convulsion, etc.