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3. Low serum chloride suggests an electrolyte derangement. 4. Low anti-nuclear antibodies: Anti-nuclear antibodies are raised in connective tissue disorders eg systemic lupus erythematosus. However, a negative value rules out this possibility.
1 Potassium chloride (found in salt substitutes) can lower your blood chloride levels but raise your urine chloride levels. 2  Tests for sodium, potassium, and bicarbonate usually are done at the same time as a blood test for chloride.ests for sodium, potassium, and bicarbonate are usually done at the same time as a blood test for chloride. Most of the chloride in your body comes from the salt (sodium chloride) you eat. Chloride is absorbed by your intestines when you digest food. Extra chloride leaves your body in your urine.