Certain addictive chemicals are dopamine agonists (meaning that they increase dopamine levels in the body), including heroin, alcohol, nicotine, marijuana and cocaine. Cocaine and amphetamines prevent dopamine reuptake, which results in too much dopamine being left in the synapses between neurons.
For tourists, Harlem offers a ton of historic landmarks such as the Apollo Theater, Museum of New York, and Sylvia's Soul Food. This is one of the centers of African-American culture going back to the early 20th century and even a simple stroll down Astor Row (135th Street) can be educational.f you walk 3 blocks you are on 125th street where the famed Apollo Theater resides, amonst a big shopping area. There is always a high presence of police in the area which tends to make you feel safe. 122nd street runs from east to west, starting at Broadway and ending at Second avenue.
The Globe Theater was where Romeo and Juliet would have been performed during the Middle Ages. It was built in 1599, but on June 1613 it caught on fire during a play and was destroyed. The Globe was rebuilt in 1614, but was later closed in 1642 by the Puritans, and then in 1644 it was destroyed once again to make room for tenements.