Research has demonstrated that many individuals with Crohnâs ileitis share a genetic mutation that may play a significant role in disease development. A hypersensitive immuno-response to a pathogenic presence, such as bacteria, within the gastrointestinal tract is also suspected of contributing to the disease's onset.
Secondary osteoarthritis occurs less frequently than primary (also known as idiopathic) osteoarthritis. Primary osteoarthritis means that there is no known cause for the joint breakdown.
osteoarthritis-chronic breakdown of cartilage in the joints; the most common form of arthritis occurring usually after middle age. degenerative arthritis, degenerative joint disease. arthritis-inflammation of a joint or joints.