914-765-0688. 1  Beehive Restaurant, serving Traditional American with a few Mediterranean dishes, is located at 30 Old Route 22, Armonk, NY 10504 in Westchester County. 2  The Cafe at Mariani Gardens is located at 45 Bedford Road in Armonk, NY 10504 in Westchester County.
The Discovery of the lac Operon. In 1961, Francois Jacob and Jacques Monod proposed the operon model of gene regulation in bacteria. The model was based on their study of the genes in E. coli that code for enzymes that affect the breakdown of lactose. Francois Jacob and Jacques Monod. Photo courtesy of Archive Photo. Because of the pioneering work of Jacob and Monod, the lac operon is typically used to illustrate gene regulation in bacteria.
The Trp operon in E. coli is turned on by default. The lac operon in E. coli is turned off when lactose is not present. A repressor binds to the operator and prevents RNA polymerase from binding to the promoter. When allolactose (closely related to lactose) is present, it binds to the repressor and prevents the repressor from binding. In this way, the presence of lactose allows the operon to be turned on to express the genes need to use lactose.