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double-blind procedure-an experimental procedure in which neither the subjects of the experiment nor the persons administering the experiment know the critical aspects of the experiment; a double-blind procedure is used to guard against both experimenter bias and placebo effects.ouble-blind procedure-an experimental procedure in which neither the subjects of the experiment nor the persons administering the experiment know the critical aspects of the experiment; a double-blind procedure is used to guard against both experimenter bias and placebo effects.
Double-Blind Placebo-Controlled Clinical Trial Thus, a double-blind, placebo-controlled clinical trial is a medical study involving human participants in which neither side knows who's getting what treatment and a placebo is given to a control group. Before getting to this stage, researchers often perform animal studies, clinical trials not involving a control group, and single-blind studies.