Inappropriate footwear can cause chronic foot and ankle pain. According to Dr. Ray McClanahan, a Portland, Oregon-based sports podiatrist and a leader in conservative foot care, most foot problems, including ankle problems, are caused by inappropriate footwear.
This type of Down syndrome, which accounts for 95% of cases, is called trisomy 21. Down syndrome is usually caused by an error in cell division called nondisjunction.. Nondisjunction results in an embryo with three copies of chromosome 21 instead of the usual two. Prior to or at conception, a pair of 21st chromosomes in either the sperm or the egg fails to separate.
There are three kinds of Down syndrome: 1  Trisomy 21. This is the most common kind. 2  Mosaic Down syndrome. People with this condition have some cells with three copies of chromosome 21, but other cells have the usual two copies. 3  Translocation Down syndrome.