Vestergaard et al have reported dermoscopy assessment is more accurate than clinical evaluation by naked eye for the diagnosis of cutaneous melanoma (odds ratio = 15.6, P = .016). In this study, the mean sensitivity in the diagnosis of melanoma was 74% for the examination by naked eye and 90% for dermoscopy.
a genetic disorder is a disease that is caused by a change or mutation in an individual s dna sequence single gene disorders disorders caused by defects in one particular gene often with simple and predictable inheritance patterns dominant diseases single gene disorders that occur when an individual has one altered copy of the relevant gene and one healthy copy for example huntington s disease
Each of these mutations can cause a variety of different diseases and conditions. Read on to learn what these mutations are and what disorders they can cause. slide 1 of 8. The causes of chromosomes mutation occur when there is any change in the arrangement or structure of the chromosomes.These mutations occur most often during meiosis during the stage when crossing over occurs. There are several different mutation types that result in chromosomal structure change.This change in structure leads to serious changes in an organisms' phenotype and genotype. If essential parts of the DNA are affected by chromosomal mutations, a foetus can be aborted prior to birth without the mother's control.ach of these mutations can cause a variety of different diseases and conditions. Read on to learn what these mutations are and what disorders they can cause. slide 1 of 8. The causes of chromosomes mutation occur when there is any change in the arrangement or structure of the chromosomes.