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Inflammation may result in organ damage. Blood clotting during sepsis reduces blood flow to limbs and internal organs, depriving them of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, infection leads to a life-threatening drop in blood pressure, called septic shock.
Possible cause. The low blood pressure and inflammation patients experience during sepsis may lead to brain damage that causes cognitive problems. Sepsis patients also frequently become delirious, a state known to be associated with Alzheimer's disease.t can start as a reaction to an infection, such as pneumonia, and go on to damage the body itself. When organs are damaged, the condition is known as severe sepsis. Sepsis affects hundreds of thousands of patients each year, and about 40 percent of people with the illness die from it.