Signs of physical and emotional exhaustion: 1  Chronic fatigue. 2  In the early stages, you may feel a lack energy and feel tired most days. 3  In the latter stages, you feel physically and emotionally exhausted, drained, and depleted, and you may feel a sense of dread for what lies ahead on any given day. 4  Insomnia.
Clinical Trials. Itraconazole is effective and safe in the treatment of vulvovaginal candidiasis 8-15 (see Table 1). Treatment regimens of itraconazole 200mg/day for 3 consecutive days 8,9,11 or 200mg given twice in one day 9,12,14 have resulted in a high mycological and clinical cure.able 1: Studies evaluating the efficacy of itraconazole in the treatment of vulvovaginal candidiasis. Table 2: Studies evaluating the efficacy of itraconazole in the prophylactic treatment of vulvovaginal candidiasis.
As with allopurinol treatment, the dose should be slowly increased. The recommended dose of probenecid is 250 mg, twice daily, for the first week, increasing to 500 mg, twice daily, for the second week and then increasing by 500 mg in subsequent months to a maximum of 2000 mg, daily in divided doses.oncurrent administration of low dose NSAIDs (e.g. naproxen 250 mg, twice daily) or colchicine (0.5 mg daily or twice daily) during this two week period, and for the following three to six months (or longer in tophaceous gout), is strongly recommended to help prevent flares.