On the one hand, this type of organizational structure benefits from having individuals entirely dedicated to one function. In some cases, there can be cost savings and efficiency gains in combining functions in this way. However, this type of organizational structure is prone to conflict.
The alpha subunit (RpoA) initiates RNAP assembly by dimerising to form a platform on which the beta subunits can interact. The alpha subunit consists of a N-terminal domain (NTD) and a C-terminal domain (CTD), connected by a short linker.
In most prokaryotes, a single RNA polymerase species transcribes all types of RNA. Figure 10-7 shows the structure of RNA polymerase from E. coli.We can see that the enzyme consists of four different subunit types.n most prokaryotes, a single RNA polymerase species transcribes all types of RNA. Figure 10-7 shows the structure of RNA polymerase from E. coli.