Definition of Speech Impairment. A speech impairment is a condition in which the ability to produce speech sounds that are necessary to communicate with others is impaired. Speech impairments can be mild, such as occasionally mispronouncing a couple of words, to severe, such as not being able to produce speech sounds at all.
methotrexate (Oral route) Only use for life-threatening neoplastic disease or severe rheumatoid arthritis and psoriasis unresponsive to other therapies. Death, fetal death and/or congenital anomalies, lung disease, tumor lysis syndrome, fatal skin reactions, and Pneumocystis carinii pneumonia have been reported.
Why It Is Used. Methotrexate reduces inflammation caused by rheumatoid arthritis. It is the most common DMARD used to treat rheumatoid arthritis. Methotrexate may be used: 1  In the early stages of rheumatoid arthritis to prevent disease progression. 2  In combination with other medicines such as other DMARDs.all your doctor if you have: 1  Hives. 2  Signs of an infection, such as a sore throat, fever, sneezing, or coughing. 3  Bloody vomit. 4  Signs of unusual bleeding or bruising, such as black and tarry stools or blood in the urine. 5  Diarrhea. 6  Stomach pain.