Definition of Speech Impairment. A speech impairment is a condition in which the ability to produce speech sounds that are necessary to communicate with others is impaired. Speech impairments can be mild, such as occasionally mispronouncing a couple of words, to severe, such as not being able to produce speech sounds at all.
methotrexate (Oral route) Only use for life-threatening neoplastic disease or severe rheumatoid arthritis and psoriasis unresponsive to other therapies. Death, fetal death and/or congenital anomalies, lung disease, tumor lysis syndrome, fatal skin reactions, and Pneumocystis carinii pneumonia have been reported.
Methotrexate is the drug used. for medical management of ectopic pregnancy at King Edward Memorial Hospital. Methotrexate is a folic acid antagonist (anti-metabolite) which prevents the growth of. rapidly dividing cells including trophoblasts and fetal cells by interfering with DNA. synthesis.