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The most common Topamax side effects when taken alone by adults with epilepsy are: 1  Tingling of the arms and legs. 2  Weight loss. 3  Sleepiness. A loss of appetite (anorexia) 4  Dizziness. Memory problems.
Re: TOPAMAX - Side Effects - Taste Perversion (Soda/Soft Drinks) I started Topamax less than 3 weeks ago but I gave up soda because I am at risk of getting diabetes and no way in hell will I drink that diet crap. I gave up soda before taking the medication. I had a coke a few days ago and it tasted flat.