Meta analyses are only as good as the quality of the underlying studies, which in this case is not very good. Some studies published in quality journals suggest that berberine's positive effects may stem from the fact that it activates AMP-Kinase, which is what metformin does.
Figure 34-2 Medial thigh furrow (wide line) is surface depression extending from proximal anterior to distal posterior thigh. Furrow divides area into medial thigh (proximal) and medial knee (distal). Figure 34-3 Full view of medial thigh/knee contour drawings. A, Right medial thigh, with patient standing and raising left thigh. This view demonstrates medial thigh furrow. B, Left medial thigh, with patient standing and raising right thigh.
Medial Moraine A medial moraine is found on top of and inside an existing glacier. Medial moraines are formed when two glaciers meet. Two lateral moraines from the different glaciers are pushed together. This material forms one line of rocks and dirt in the middle of the new, bigger glacier. If a glacier melts, the medial moraine it leaves behind will be a long ridge of earth in the middle of a valley.