Research has demonstrated that many individuals with Crohnâs ileitis share a genetic mutation that may play a significant role in disease development. A hypersensitive immuno-response to a pathogenic presence, such as bacteria, within the gastrointestinal tract is also suspected of contributing to the disease's onset.
Secondary osteoarthritis occurs less frequently than primary (also known as idiopathic) osteoarthritis. Primary osteoarthritis means that there is no known cause for the joint breakdown.
OA Options. Osteoarthritis (OA) is the most common form of arthritis. Typical age of onset is mid to late 40s, with obesity and prior sports injuries increasing the chance of having it. OA is a painful type of arthritis affecting the joints. Itâs a degenerative condition, which means it worsens over time. One of the characteristics of OA is loss of cartilage due to the mechanical breakdown of the joint. This loss of protective cushion can cause debilitating pain and weakness, and may lead to costly joint replacement surgery.