Research has demonstrated that many individuals with Crohnâs ileitis share a genetic mutation that may play a significant role in disease development. A hypersensitive immuno-response to a pathogenic presence, such as bacteria, within the gastrointestinal tract is also suspected of contributing to the disease's onset.
Secondary osteoarthritis occurs less frequently than primary (also known as idiopathic) osteoarthritis. Primary osteoarthritis means that there is no known cause for the joint breakdown.
Osteoarthritis. Osteoarthritis is the most common type of arthritis in the UK which is also known as âwear and tearâ arthritis or âdegenerative joint diseaseâ. It manifests itself as damage to the surface of the joints.More than 8 million people in the UK have osteoarthritis.his occurs in severe cases of osteoarthritis where the cartilage has degraded to such an extent that it no longer provides any cover for these bones. As these bones rub together they cause each other to wear away and can eventually, distort the shape of the joint.