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The most common Topamax side effects when taken with other medicines by children with epilepsy are: 1  Fatigue. 2  Sleepiness. 3  Lack of appetite (anorexia) 4  Nervousness. Problems concentrating or paying attention.  Memory 1  problems. Aggressiveness.  Weight loss.
Although I don't know exactly what is causing it, I have a few side notes to comment on in this thread. I have noticed that many anti-seizure medicines seems to have memory loss as one of the side effects. Topamax has earned a nickname of Dopamax for causing huge amounts of memory problems.