The blood clotting system or coagulation pathway, like the complement system, is a proteolytic cascade. Each enzyme of the pathway is present in the plasma as a zymogen (inactive form), which on activation undergoes proteolytic cleavage to release the active factor from the precursor molecule. The coagulation pathway functions as a series of positive and negative feedback loops which control the activation process.
Spring Yard Zone is the third Zone in the original Sonic the Hedgehog. It is an urban level with many springs and bumpers, resembling a pinball machine. There are many secret areas in this zone. Act 2 has two Robotnik signs (goals) and as such, can be ended through two possible routes.
A safety feature called the crumple zone, introduced to cars in the 50s, is designed to absorb the impact in a crash and protect passengers. The crumple zones are often likened to crushing a soda can, sacrificing everything in its path. The most popular crumple zone locations are in the front and the rear of the car. For anyone who puts their dogs in the back, this is absolutely terrifying.