Fax Number: (706) 632-3278. Blue Ridge, incorporated on October 24, 1887, is the county seat of Fannin County. The city is named for the southern reach of the Appalachian Mountain Range that stretches into that area.
HLA-DR HLA-DR is a MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR and its ligand, a peptide of 9 amino acids in length or longer, constitutes a ligand for the T-cell receptor. HLA were originally defined as cell surface antigens that mediate graft-versus-host disease, which resulted in the rejection of tissue transplants in HLA-mismatched donors.
Sometimes HLA gene testing is used to aid in the diagnosis of an autoimmune disease. The HLA system is one of the mechanisms involved in the body's recognition of self and non-self antigens and the immune response to foreign substances.t identifies the major HLA genes a person has inherited and the corresponding antigens (proteins) that are present on the surface of their cells. These antigens help the body's immune system distinguish which cells are self and which are foreign or non-self..