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Telomere Definition. Telomeres are short tandem repeats of nucleotides at the ends of chromosomes. Let's break this definition down a bit. Nucleotides are the building blocks of DNA, which is the carrier of genetic information.
Multiple methods have been developed for the study of telomeres. These techniques include quantification of telomere length by terminal restriction fragmentationâwhich was one of the earliest tools used for length assessmentâmaking it the gold standard in telomere biology.