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Advantages and disadvantages of monoclonal antibodies in treatment of disease. The potential advantages of using monoclonal antibodies in the treatment of cancer are great because monoclonal antibodies only bind to the specific cancer cells that need treatment. Healthy cells are not affected at all. iStock photo.com. 1  Diagnosis of disease-monoclonal antibodies can be made which bind to specific antigens on blood clots or on cancer cells. 2  Treatment of disease-monoclonal antibodies can be used to carry drugs to specific tissues.
All treatments have side effects. Some side effects depend on the type of cell the MAB is targeting. They may also depend on whether the MAB has a drug or radioactive substance attached to it. The most common side effect of all monoclonal antibodies is an allergic reaction to the drug.onoclonal antibodies are a type of biological therapy. They can treat some types of cancer. Monoclonal means one type. So each monoclonal antibody (MAB) drug is a lot of copies of one specific type of antibody.