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Guaifenesin is used to control cough and is sometimes combined with dextromethorphan, an antitussive (cough medicine), such as in Mucinex DM or Robitussin DM. Side-effects. Side-effects of guaifenesin include nausea, vomiting, formation of kidney stones, diarrhea, and constipation. Nausea and vomiting can be reduced by taking guaifenesin with meals. The risk of forming kidney stones during prolonged use can be reduced by maintaining good hydration and increasing the pH of urine.
Mucinex DM contains two key ingredients: dextromethorphan and guaifenesin. Dextromethorphan can cause you to get a false positive for Heroin, Opiates, Morphine on a drug test. Guaifenesin is an expectorant that helps thin and loosen mucus in the lungs, making it easier to cough up the mucus.