What are the possible side effects of epoetin alfa (Epogen, Procrit)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Contact your doctor if you feel weak, lightheaded, or short of breath, or if your skin looks pale.
The land acquired by the United States in the Louisiana Purchase included the current state of Louisiana. In purchasing France's territories west of the Mississippi, Jefferson took a risk by extending the power of the federal government and testing the limits of the U.S. Constitution.
History & Culture. The Louisiana Purchase was one of the largest land deals in history. In 1803, the United States paid approximately $15 million dollars for France for over 800,000 square miles of land. This land deal was arguably the greatest achievement of Thomas Jefferson's presidency but also posed a major philosophical problem for Jefferson.