Definition. 1  A lumpectomy is a type of surgery used to treat breast cancer. 2  Lumpectomy is a surgical treatment for newly diagnosed breast cancer. 3  The extent and severity of a cancer is evaluated or staged according to a fairly complex system.
Common side effects when used by mouth include shortness of breath, headache, numbness, depression, skin dryness, itchiness, hair loss, vomiting, muscle pains, and vision changes. Other severe side effects include high white blood cell counts and blood clots. When used as a cream side effects include skin redness, peeling, and sun sensitivity. Use during pregnancy is known to harm the baby. It is in the retinoid family of medications. Tretinoin was patented in 1957 and approved for medical use in 1962.
contraindications Pregnancy and known hypersensitivity to retinoids prohibit bexarotene's use. adverse effects Life-threatening adverse reactions include acute pancreatitis, leukopenia, and neutropenia. Other serious side effects include asthenia, infection, anemia, and hypothyroidism. Among the drug's common side effects are headache, nausea, abdominal pain, and diarrhea. A retinoid that binds to retinoid X receptors, upregulating their activity by either removing negative transcription control or by facilitating transcription. It is FDA-approved for treating cutaneous T cell lymphoma, and has been used off label for lung and breast cancer, and Kaposi sarcoma.