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Telomere Definition. Telomeres are short tandem repeats of nucleotides at the ends of chromosomes. Let's break this definition down a bit. Nucleotides are the building blocks of DNA, which is the carrier of genetic information.
Telomerase is a crucial enzyme that controls and maintains telomeres. These are the tips of chromosomes that a) protect DNA from molecular attack and b) prevent strands of genetic material from sticking to each other. The enzyme is active in stem cells, germ cells, and tumour cells.