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Guaifenesin is used to control cough and is sometimes combined with dextromethorphan, an antitussive (cough medicine), such as in Mucinex DM or Robitussin DM. Side-effects. Side-effects of guaifenesin include nausea, vomiting, formation of kidney stones, diarrhea, and constipation. Nausea and vomiting can be reduced by taking guaifenesin with meals. The risk of forming kidney stones during prolonged use can be reduced by maintaining good hydration and increasing the pH of urine.
5 Reviews. 5 Reviews. Mucinex DM is a cough medicine that contains dextromethorphan, a cough suppressant, and guaifenesin, an expectorant that helps loosen mucus in your throat and lungs.This combination of two drugs helps to loosen mucus or phlegm and thin out bronchial secretions, making coughs more productive. Reviews. 5 Reviews. Mucinex DM is a cough medicine that contains dextromethorphan, a cough suppressant, and guaifenesin, an expectorant that helps loosen mucus in your throat and lungs.