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Advantages and disadvantages of monoclonal antibodies in treatment of disease. The potential advantages of using monoclonal antibodies in the treatment of cancer are great because monoclonal antibodies only bind to the specific cancer cells that need treatment. Healthy cells are not affected at all. iStock photo.com. 1  Diagnosis of disease-monoclonal antibodies can be made which bind to specific antigens on blood clots or on cancer cells. 2  Treatment of disease-monoclonal antibodies can be used to carry drugs to specific tissues.
The target is the CD30 cell membrane protein which is expressed on the surface of certain types of lymphoma cells, including Hodgkin's Reed-Sternberg cells, anaplastic large-cell lymphoma cells, embryonal carcinoma cells, and other cells found in select types of non-Hodgkin lymphoma.dcetris uses the antibody to deliver the drug to the appropriate lymphoma cells. Conventional therapy fails to produce remission in approximately 15 to 30 percent of patients with Hodgkin's lymphoma, Younes reported.