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Telomere Definition. Telomeres are short tandem repeats of nucleotides at the ends of chromosomes. Let's break this definition down a bit. Nucleotides are the building blocks of DNA, which is the carrier of genetic information.
When the telomere becomes too short, the chromosome reaches a critical length and can no longer replicate. This means that a cell becomes old and dies by a process called apoptosis. Telomere activity is controlled by two mechanisms: erosion and addition. Erosion, as mentioned, occurs each time a cell divides.