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A Single nucleotide polymorphism or SNP (pronounced snip) is a DNA sequence variation occurring when a single nucleotide-A, T, C, or G-in the genome (or other shared sequence) differs between members of a species (or between paired chromosomes in an individual).NA sequence variations that occur when a single nucleotide (A, T, C, or G) in the genome sequence is altered. Each individual has many single nucleotide polymorphisms that together create a unique DNA pattern for that person.
If a SNP occurs within a gene, then the gene is described as having more than one allele. In these cases, SNPs may lead to variations in the amino acid sequence. SNPs, however, are not just associated with genes; they can also occur in noncoding regions of DNA.Although a particular SNP may not cause a disorder, some SNPs are associated with certain diseases.These associations allow scientists to look for SNPs in order to evaluate an individual's genetic predisposition to develop a disease.n these cases, SNPs may lead to variations in the amino acid sequence. SNPs, however, are not just associated with genes; they can also occur in noncoding regions of DNA. Although a particular SNP may not cause a disorder, some SNPs are associated with certain diseases.