Ronda, James P. (1998). Voyages of Discovery: Essays on the Lewis and Clark Expedition. Montana Historical Society Press, Helena, MT. Woodger, Elin and Brandon Toropov (2004). Encyclopedia of the Lewis and Clark Expedition. Facts on File, New York, NY. You can uncover more fascinating food history on Toriâs website: The History Kitchen.
Muscle contraction results from an attachmentâdetachment cycle between the myosin heads extending from myosin filaments and the sites on actin filaments. The myosin head first attaches to actin together with the products of ATP hydrolysis, performs a power stroke associated with release of hydrolysis products, and detaches from actin upon binding with new ATP. The detached myosin head then hydrolyses ATP, and performs a recovery stroke to restore its initial position.
The attraction between the myosin head and the myosin-binding site of actin are strong enough that the bond can form spontaneously. Once the two proteins are bound, the myosin protein undergoes a conformational change, or a change in protein shape, that 'cocks' the head.