An average subdivision of 200 homes (with four people per house) generates about 3,270 kg of total N per square kilometer (1 square kilometer has about 247 acres) each year [= 200 homes x 4 people x 11.2 grams total N per day x 365 days in a year].ikewise, assuming a fertilizer application rate of 40 â 80 kg total N per acre per year for agricultural crops, fertilizer can add 10,000 â 20,000 kg of total N in 1 square kilometer (247 acres).
What is Opdivo? Opdivo (nivolumab) is a cancer medicine that works with your immune system to interfere with the growth and spread of cancer cells in the body. Opdivo is used to treat a certain type of melanoma (skin cancer) that cannot be treated with surgery, or that has spread to other parts of the body. Opdivo is also used to treat a certain type of non-small cell lung cancer. Nivolumab may increase the chance of a longer survival time in people with this type of lung cancer. Opdivo is used for melanoma or lung cancer only if your tumor has a specific genetic marker that your doctor will test for.
Nivolumab is the generic name for the trade drug name OpdivoÂ®. In some cases, health care professionals may use the generic name nivolumab when referring to the trade name OpdivoÂ®. Nivolumab is a targeted therapy. It is a human programmed death receptor-1 (PD-1) blocking antibody.