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Graves' disease is one of the most common causes of hyperthyroidism in women. This again is an autoimmune disorder in which the thyroid gets enlarged and leads to greater production of thyroxine. There are various types of thyroid infections that may lead to the inflammation of the gland.
The main cause is unknown, but thyroid nodules and thyroid enlargement are more common in women than men and increase in frequency with age. Women often develop thyroid enlargement during pregnancy and the menopause. If you have a nodule or swelling in your neck you should see your doctor with a minimum of delay.