inflammation-a response of body tissues to injury or irritation; characterized by pain and swelling and redness and heat.. redness, swelling, and fever in a local area of the body, often with pain and disturbed function, in reaction to an infection or to a physical or chemical injury. 2. the act or fact of inflaming. 3. the state of being inflamed.
Farthest North- Alaska. Farthest East-This is not easy to answer. On a map of the USA, Maine would seem to be the farthest east.
So Alaska is farther east than almost anywhere else on earth, including Maine. Farthest South-Hawaii (the Hawaiian Islands). There is a jog in the International Dateline to put Alaska is in the old day. Alaska to the north, Hawaii to the west and south, and Maine to the east.