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Advantages and disadvantages of monoclonal antibodies in treatment of disease. The potential advantages of using monoclonal antibodies in the treatment of cancer are great because monoclonal antibodies only bind to the specific cancer cells that need treatment. Healthy cells are not affected at all. iStock photo.com. 1  Diagnosis of disease-monoclonal antibodies can be made which bind to specific antigens on blood clots or on cancer cells. 2  Treatment of disease-monoclonal antibodies can be used to carry drugs to specific tissues.
Making monoclonal antibodies. An important advance in the use of antibodies was the recognition that it was possible to produce a monoclonal population of antibodies. This is a procedure that is in many ways analogous to isolating a cDNA from a cDNA library.nti-idiotype antibodies, which are antibodies against the binding domain of another antibody, can sometimes be used to mimic the structure of the original antigen. Antibody Specificity. perhaps most importantly, it is important to consider the question of antibody specificity and reactivity.