Radiesse needs to be injected deeper into the dermal area, where there is enough soft tissue to stimulate new collagen growth. Injections of Radiesse may be more painful than Restylane, Juvederm, or those fillers containing lidocaine, and a local anesthetic is usually used before injecting Radiesse. Restylane may provide a more natural look initially, but it used more for finer lines, and is not injected as deeply as Radiesse.
Grapefruit, as the fruit or juice, is generally recognized as safe by the FDA. However, grapefruit affects MANY other medicines. Before taking grapefruit, talk with your healthcare provider if you take any other medicines. Do not take grapefruit seed extract products that contain preservatives.These can cause serious side effects such as vomiting, seizures, collapse, and coma. Do not get grapefruit seed extract in your eyes or nose. Do not use it on your genitals or rectum. It can cause severe irritation.If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.o not get grapefruit seed extract in your eyes or nose. Do not use it on your genitals or rectum. It can cause severe irritation. If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.
1 Some may advise not to take the drug with grapefruit juice. 2  If itâs OK to have grapefruit juice, there will be no mention of it in the guide or information sheet. 3  Read the Drug Facts label on your non-prescription medicine, which will let you know if you shouldnât have grapefruit or other fruit juices with it.rapefruit juice and fresh grapefruit can interfere with the action of some prescription drugs, as well as a few non-prescription drugs. This interaction can be dangerous, says Shiew Mei Huang, acting director of the Food and Drug Administrationâs Office of Clinical Pharmacology.