A defective gene on chromosome 15 causes Tay-Sachs disease. This defective gene causes the body to not make a protein called hexosaminidase A. Without this protein, chemicals called gangliosides build up in nerve cells in the brain, destroying brain cells.
The North Carolina state sales tax rate is 4.75%, and the average NC sales tax after local surtaxes is 6.9%. Counties and cities in North Carolina are allowed to charge an additional local sales tax on top of the North Carolina state sales tax. 92 out of the 100 counties in North Carolina collect a local surtax of 2%. Most groceries are taxed at a reduced rate of 2% (excluding things like candy and soft drinks).
The South Carolina state sales tax rate is 6%, and the average SC sales tax after local surtaxes is 7.13%. 1  Groceries and prescription drugs are exempt from the South Carolina sales tax.  Counties and cities can charge an additional local sales tax of up to 3%, for a maximum possible combined sales tax of 9%.