Fax Number: (706) 632-3278. Blue Ridge, incorporated on October 24, 1887, is the county seat of Fannin County. The city is named for the southern reach of the Appalachian Mountain Range that stretches into that area.
HLA-DR HLA-DR is a MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR and its ligand, a peptide of 9 amino acids in length or longer, constitutes a ligand for the T-cell receptor. HLA were originally defined as cell surface antigens that mediate graft-versus-host disease, which resulted in the rejection of tissue transplants in HLA-mismatched donors.
Q: Why can it be so difficult to find an HLA-matched donor? A: The best potential for an HLA match is within the family. Each person inherits one A, B, C, DR and DQ antigen from each parent. Thus, we have 2 HLA-A antigens, two HLA-B antigens and so on. The number of different HLA combinations is limited to the HLA types of the parents.