Figure 2. Evolutionary layers of the X and Y chromosomes. (a) Comparative mapping of genes from the human X in marsupial mammals detected an ancient region conserved on the X in all mammals and denoted XCR, as well as a recently added region denoted XAR that is autosomal in marsupials.
Poliovirus, the causative agent of poliomyelitis (commonly known as polio), is a human enterovirus and member of the family of Picornaviridae. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA genome that is about 7500 nucleotides long.
Two polio vaccines are used throughout the world to provide immunity to the virus that causes poliomyelitis (or polio). The first was developed by Jonas Salk through the use of HeLa cells and first tested in 1952.he Salk vaccine, or inactivated poliovirus vaccine (IPV), is based on three wild, virulent reference strains, Mahoney (type 1 poliovirus), MEF-1 (type 2 poliovirus), and Saukett (type 3 poliovirus), grown in a type of monkey kidney tissue culture (Vero cell line), which are then inactivated with formalin.