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From Wikipedia, the free encyclopedia. Zika virus (ZIKV) is a member of the Flaviviridae virus family and the flavivirus genus. In humans, it causes a disease known as Zika fever. It is related to dengue, yellow fever, West Nile and Japanese encephalitis, viruses that are also members of the virus family Flaviviridae.t is most closely related to the Spondweni virus and is one of the two viruses in the Spondweni virus clade. The virus was first isolated in 1947 from a rhesus monkey in the Zika Forest of Uganda, Africa and was isolated for the first time from humans in 1968 in Nigeria.
More rarely observed symptoms include digestive problems (abdominal pain, diarrhoea, constipation), mucous membrane ulcerations (aphthae), and pruritus. Zika virus infection causes a mild disease and, other than notification, no particular action is required.However, as Zika infection may cause a rash that could be confused with more serious diseases such as measles or dengue, these more serious diseases do need to be ruled out.ika virus infection causes a mild disease and, other than notification, no particular action is required. However, as Zika infection may cause a rash that could be confused with more serious diseases such as measles or dengue, these more serious diseases do need to be ruled out.