One of these mechanisms involves the reduced availability of an essential nutrient, thiamine, to the brain as a consequence of chronic alcohol consumption. This article describes the normal role of thiamine in brain functioning as well as the pathological consequences that result from thiamine deficiency.
An early interest in the outdoors. Daniel Boone was born near Reading, Pennsylvania, on November 2, 1734, the sixth of eleven children born to Squire Boone, a farmer and land speculator (a person who buys land hoping that it will increase in value and be sold for a profit), and Sarah Morgan.
Boone was elected to the first of his three terms in the Virginia General Assembly, during the Revolutionary War, and fought in the Battle of Blue Licks in 1782. Blue Licks, a Shawnee victory over the Patriots, was one of the last battles of the Revolutionary War, coming after the main fighting ended in October 1781.