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Telomere Definition. Telomeres are short tandem repeats of nucleotides at the ends of chromosomes. Let's break this definition down a bit. Nucleotides are the building blocks of DNA, which is the carrier of genetic information.
They work like the plastic tips of shoelaces to protect the ends of chromosomes, the strings of genes in the heart of every cell that tell it what to do. Without telomeres, our cells would lose the ability to divide and would quickly die off. Scientists have been fascinated by telomeres for several decades.