Transient flushing is also a common side effect of alcohol, particularly in heavy drinkers. It is due to acetaldehyde, the main breakdown product of alcohol. Acetaldehyde is thought to cause flushing by stimulating release of histamine.
The right two lanes of the Tri-State Tollway become exit only for the ramp connection to Interstate 94/Bishop Ford (Calumet) Expressway west (north) to Chicago and Illinois 394/Bishop Ford (Calumet) Expressway south to Crete and Danville. An END Interstate 294 sign is posted on this guide sign.
The trunkline is a freeway from the MichiganâOhio state line near Lambertville to the city of Standish, and it follows the Lake Huron shoreline from there to its northern terminus. Serving the cities of Ann Arbor and Flint, US 23 acts as a freeway bypass of the Metro Detroit area.