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1 Large numbers of red blood cells may be caused by bleeding in the joint from injury, inflammation, or abnormal clotting of the blood. 2  Large numbers of white blood cells may be caused by gout, pseudogout, other types of arthritis (such as rheumatoid arthritis), psoriatic arthritis, injury, or infection.nfection, bleeding, or damage to the tendon, nerve, or joint is rare. Sometimes your doctor may not be able to draw any fluid out. The joint space may be too small, you may have scar tissue in the joint space, or there may not be any fluid in the joint. The joint may be sore for 1 to 2 days after the procedure.
Urinalysis - This exam can measure the protein and cells in your urine which can be an early warning of kidney disease in lupus patients. Complete blood count (CBC) - measures the cell counts in your blood which include white blood cells, red blood cells, hemoglobin and platelet counts. White blood cells can be decreased in lupus and may be a sign of active disease or drug-related side effect. Patients with lupus may have a mild anemia manifested by a low hemoglobin level. Causes of anemia include iron deficiency, active inflammation or less frequently, hemolytic anemia which is caused by autoantibodies to red blood cells.