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What happens if I overdose (Depakote, Depakote ER, Depakote Sprinkles)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include sleepiness or drowsiness, shallow breathing, weak pulse, or loss of consciousness. Drinking alcohol can increase certain side effects of divalproex sodium. Divalproex sodium may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid exposure to sunlight or tanning beds.
For complex or partial absence seizures, the starting dose of Depakote ER is 15 mg per kg once daily (about 6.8 mg per pound once daily).Your healthcare provider will probably increase your dose slowly until your seizures are controlled or until you experience bothersome side effects.he recommended starting Depakote ER dose for treating manic or mixed episodes associated with bipolar disorder is 25 mg per kg of body weight once daily (about 11.4 mg per pound once daily).