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The potential of NADH and FADH 2 is converted to more ATP through an electron transport chain with oxygen as the terminal electron acceptor. Most of the ATP produced by aerobic cellular respiration is made by oxidative phosphorylation.lthough there is a theoretical yield of 38 ATP molecules per glucose during cellular respiration, such conditions are generally not realized due to losses such as the cost of moving pyruvate (from glycolysis), phosphate, and ADP (substrates for ATP synthesis) into the mitochondria.
The electron transport chain in the cell is the site of oxidative phosphorylation in prokaryotes. The NADH and succinate generated in the citric acid cycle are oxidized, releasing energy to power the ATP synthase. Oxidative phosphorylation (or OXPHOS in short) is the metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing energy which is used to reform ATP. In most eukaryotes, this takes place inside mitochondria. Almost all aerobic organisms carry out oxidative phosphorylation.