A defective gene on chromosome 15 causes Tay-Sachs disease. This defective gene causes the body to not make a protein called hexosaminidase A. Without this protein, chemicals called gangliosides build up in nerve cells in the brain, destroying brain cells.
The North Carolina state sales tax rate is 4.75%, and the average NC sales tax after local surtaxes is 6.9%. Counties and cities in North Carolina are allowed to charge an additional local sales tax on top of the North Carolina state sales tax. 92 out of the 100 counties in North Carolina collect a local surtax of 2%. Most groceries are taxed at a reduced rate of 2% (excluding things like candy and soft drinks).
What is Sales Tax? Sales tax is imposed on the sale of goods and certain services in South Carolina. The statewide sales and use tax rate is six percent (6%). Counties may impose an additional one percent (1%) local sales tax if voters in that county approve the tax. Generally, all retail sales are subject to the sales tax. How to File ST-3 State Sales and Use Tax Return: Sales and Use Tax accounts are set up with a monthly filing frequency.