An average subdivision of 200 homes (with four people per house) generates about 3,270 kg of total N per square kilometer (1 square kilometer has about 247 acres) each year [= 200 homes x 4 people x 11.2 grams total N per day x 365 days in a year].ikewise, assuming a fertilizer application rate of 40 â 80 kg total N per acre per year for agricultural crops, fertilizer can add 10,000 â 20,000 kg of total N in 1 square kilometer (247 acres).
What is Opdivo? Opdivo (nivolumab) is a cancer medicine that works with your immune system to interfere with the growth and spread of cancer cells in the body. Opdivo is used to treat a certain type of melanoma (skin cancer) that cannot be treated with surgery, or that has spread to other parts of the body. Opdivo is also used to treat a certain type of non-small cell lung cancer. Nivolumab may increase the chance of a longer survival time in people with this type of lung cancer. Opdivo is used for melanoma or lung cancer only if your tumor has a specific genetic marker that your doctor will test for.
Classical Hodgkin Lymphoma. âOpdivo (nivolumab) is indicated for the treatment of patients with classical Hodgkin lymphoma (cHL) that has relapsed or progressed after autologous hematopoietic stem cell transplantation (HSCT) and post-transplantation brentuximab vedotin [see Clinical Studies (14.4)].