Ovaries stop functioning altogether at menopause. At that point, age-related infertility is present and natural conception can no longer occur. Normal menopause occurs in woman from about 42 to 58 years old. However, the influence of age related infertility may start 10 years before menopause.
PU leather is JUNK and ultimately I would NEVER spend $350-$500 on a chair using PU Leather or Vinyl as a material. Even if it's the best PU leather known to man the fact is that PU leather is not as comfortable, durable or cleanable as a good protected leather.
I've done a huge amount of researching and almost none talk about their chairs after, 6 months, a year, 2 years. PU quality does depends on the manufacturing process. If the PU leather is just sprayed on, they degrade after a few months. But if they undergo a calendering process, they can last longer than leather.