What are the possible side effects of epoetin alfa (Epogen, Procrit)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Contact your doctor if you feel weak, lightheaded, or short of breath, or if your skin looks pale.
The land acquired by the United States in the Louisiana Purchase included the current state of Louisiana. In purchasing France's territories west of the Mississippi, Jefferson took a risk by extending the power of the federal government and testing the limits of the U.S. Constitution.
What series of events led to the Louisiana Purchase? American pioneers used the Mississippi River and the port of New Orleans to ship goods to the East Coast and Europe. The Spanish closed the port to American trade, and the pioneers could not ship their products. Jefferson became interested in buying the port.