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Advantages and disadvantages of monoclonal antibodies in treatment of disease. The potential advantages of using monoclonal antibodies in the treatment of cancer are great because monoclonal antibodies only bind to the specific cancer cells that need treatment. Healthy cells are not affected at all. iStock photo.com. 1  Diagnosis of disease-monoclonal antibodies can be made which bind to specific antigens on blood clots or on cancer cells. 2  Treatment of disease-monoclonal antibodies can be used to carry drugs to specific tissues.
Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope. Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance.This has become an important tool in biochemistry, molecular biology and medicine.hen used as medications, the non-proprietary drug name ends in-mab (see  Nomenclature of monoclonal antibodies ), and many immunotherapy specialists use the word mab anacronymically.