The organizational structure as shown above is responsible for the peacetime organization, equipping, and training of aerospace units for operational missions. When required to support operational missions, the <answer>Secretary of Defense</answer> (SECDEF) directs the Secretary of the Air Force (SECAF) to execute a Change in Operational Control (CHOP) of these units from their administrative alignment to the operational command of a Regional Combatant Commander (CCDR). In the case of AFSPC, AFSOC, PACAF, and USAFE units, forces are normally employed in-place under their existing CCDR. Likewise, AMC forces operating in support roles retain their componency to USTRANSCOM unless chopped to a Regional CCDR.
Who directs the Secretary of the Air Force during operational missions? 
Secretary of Defense