The best-known application of the concept of pratītyasamutpāda is the scheme of Twelve Nidānas (from Pāli "nidāna" meaning "cause, foundation, source or origin"), which explain <answer>the continuation of the cycle of suffering and rebirth (saṃsāra) in detail.</answer>[note 10]
What does the scheme of Twelve Nidānas explain?
the continuation of the cycle of suffering and rebirth (saṃsāra) in detail.