as part of the health literacy screening study,21 we assembled a retrospective cohort of patients who were discharged from an ahf hospitalization at a quaternary care hospital between november 1 , 2010 and june 30 , 2013 .
all health literacy and patient outcome data were extracted from the medical center s enterprise data warehouse and research derivative databases , where data from the electronic health record ( ehr ) are stored . the medical center s institutional review board approved this study with a waiver of informed consent .
hospitalization for ahf was defined as a primary discharge diagnosis of heart failure , indicated by icd-9 billing codes 402.01 , 402.11 , 402.91 , 404.01 , 404.03 , 404.11 , 404.13 , 404.91 , 404.93 , or 428.*. this algorithm was developed for use in all - payer claims datasets22 and has been utilized in multiple prior publications to identify ahf hospitalizations.2325 patients were included if they were age 18  years or older ; race and gender were available in the ehr ; the 3 brief health literacy screen ( bhls ) items were recorded during the index hospitalization ; and the patient was discharged from the hospital to home .
patients transferred to other facilities such as rehabilitation or postacute care facilities were excluded because these patients would not typically manage their own medications and diet .
patients who were discharged with home hospice were excluded because they often had end - stage heart failure .
the first hospitalization for ahf during the study period was used as the index hospitalization .
health literacy was measured by the bhls,26,27 which consists of 3 items , each on a 5-point scale (  how often do you have problems learning about your medical condition because of difficulty understanding written information ?  ;  how confident are you filling out medical forms by yourself ?  ; and  how often do you have someone ( like a family member , friend , hospital / clinic worker , or caregiver ) help you read hospital materials ?  ) .
since 2010 , these items have been routinely administered by nursing staff as part of hospital admission intake.21 language preference and use of an interpreter were recorded in the nursing intake assessment .
implementation and widespread use of the bhls as part of nursing intake was accomplished prior to this study using a quality - improvement framework , with a focus on acceptability , adoption , appropriateness , feasibility , fidelity , and sustainability .
the bhls was implemented across all adult hospital units , the ed , and 3 primary care practices between november 2010 and april 2012 .
completion rate was 91.8% for the hospital among 55  611 adult inpatient admissions between november 2010 and september 2011.21 nurses orally administered the items and recorded patient responses as well as highest level of education , generally within the first 24  hours of hospitalization
. continued compliance with documentation of these items has been high ( 85% to 90% ) , though nurses could opt out of asking the bhls questions if the patient was unable to answer due to medical reasons such as intubation or altered mental status . the nurse - administered bhls has been shown to be a valid measure of health literacy in our health system when compared to the bhls and short test of functional health literacy in adults administered by research personnel.21,28 the bhls item addressing confidence with forms was reverse scored , and the 3 responses were summed to generate a score between 3 and 15 , where higher scores indicated higher health literacy .
this threshold is based on our prior work and was chosen to maximize sensitivity and specificity for correctly classifying patients with low health literacy compared to the short test of functional health literacy in adults.29 the primary outcome was the time from hospital discharge to death , which was censored on december 31 , 2013 .
date of death was obtained from the social security death index ( ssdi ) and by extraction from the institution s ehr , which also contains clinical documentation of deaths .
of 403 identified deaths , 286 ( 71.0% ) were identified in both social security death index and ehr ; 64 ( 15.9% ) were identified by social security death index , and 53 ( 13.2% ) were identified in the ehr ( and confirmed by chart review ) . planned secondary outcomes included time to the first rehospitalization and time to the first ed visit within 90  days of index hospital discharge .
covariates were chosen based on expected relationships with health literacy , death , or healthcare utilization .
the following covariates were recorded during the index hospitalization and extracted from the ehr : age , sex , race ( white , black , other ; by self - report),30 insurance ( private , state / federal , uninsured ) , and highest level of education .
hospital length of stay was computed by administrative time stamps , and comorbid conditions31 were measured by the elixhauser comorbidity index .
the elixhauser index includes 30 comorbid conditions and is associated with hospital length of stay , hospital charges , and mortality.32 the primary analysis tested the a priori hypothesis that patients with low health literacy had a shorter time / greater risk of the outcome of death after hospitalization for ahf .
cumulative incidence plots were constructed to visualize the relationship between health literacy level ( bhls 9 versus bhls > 9 ) and outcomes , and the log rank test was used to compare the survival distributions . adjusted analyses used a cox proportional hazards model to examine the relationships between health literacy and the primary outcome of time - to - death , adjusting for covariates age , sex , race , insurance status , education , index hospital length of stay , and the elixhauser comorbidity index .
the proportional hazards assumption was evaluated by log - log plots and tested using schoenfeld residuals.33 the same modeling approach was applied to the planned secondary outcomes of time - to - first rehospitalization and time - to - first ed visit within 90  days , in separate models .
first , we examined the relationship between health literacy and death across the range of health literacy thresholds . adjusted cox regression
was repeated for bhls dichotomized at a score of 14 ( bhls=15 , bhls < 15 ) and for continuous bhls with restricted cubic splines with 4 knots ( at 13 , 10 , 7 , and 4 ) . second , we conducted stratified analyses by age ( < 65 , 65 ) , race ( white , nonwhite ) , education ( high school , less than high school ) , and length of stay for the index hospitalization ( 5  days , > 5  days ) .
third , patients could have multiple hospitalizations over the course of the study duration ; therefore , we evaluated rehospitalizations and ed visits using robust standard errors .
no adjustment was made for multiple analyses.34 analyses were conducted using stata 12.0 ( statacorp , college station , tx ) .
as part of the health literacy screening study,21 we assembled a retrospective cohort of patients who were discharged from an ahf hospitalization at a quaternary care hospital between november 1 , 2010 and june 30 , 2013 .
all health literacy and patient outcome data were extracted from the medical center s enterprise data warehouse and research derivative databases , where data from the electronic health record ( ehr ) are stored . the medical center s institutional review board approved this study with a waiver of informed consent .
hospitalization for ahf was defined as a primary discharge diagnosis of heart failure , indicated by icd-9 billing codes 402.01 , 402.11 , 402.91 , 404.01 , 404.03 , 404.11 , 404.13 , 404.91 , 404.93 , or 428.*. this algorithm was developed for use in all - payer claims datasets22 and has been utilized in multiple prior publications to identify ahf hospitalizations.2325 patients were included if they were age 18  years or older ; race and gender were available in the ehr ; the 3 brief health literacy screen ( bhls ) items were recorded during the index hospitalization ; and the patient was discharged from the hospital to home .
patients transferred to other facilities such as rehabilitation or postacute care facilities were excluded because these patients would not typically manage their own medications and diet .
patients who were discharged with home hospice were excluded because they often had end - stage heart failure .
the first hospitalization for ahf during the study period was used as the index hospitalization .
health literacy was measured by the bhls,26,27 which consists of 3 items , each on a 5-point scale (  how often do you have problems learning about your medical condition because of difficulty understanding written information ?  ;  how confident are you filling out medical forms by yourself ?  ; and  how often do you have someone ( like a family member , friend , hospital / clinic worker , or caregiver ) help you read hospital materials ?  ) .
since 2010 , these items have been routinely administered by nursing staff as part of hospital admission intake.21 language preference and use of an interpreter were recorded in the nursing intake assessment .
implementation and widespread use of the bhls as part of nursing intake was accomplished prior to this study using a quality - improvement framework , with a focus on acceptability , adoption , appropriateness , feasibility , fidelity , and sustainability .
the bhls was implemented across all adult hospital units , the ed , and 3 primary care practices between november 2010 and april 2012 .
completion rate was 91.8% for the hospital among 55  611 adult inpatient admissions between november 2010 and september 2011.21 nurses orally administered the items and recorded patient responses as well as highest level of education , generally within the first 24  hours of hospitalization
. continued compliance with documentation of these items has been high ( 85% to 90% ) , though nurses could opt out of asking the bhls questions if the patient was unable to answer due to medical reasons such as intubation or altered mental status . the nurse - administered bhls has been shown to be a valid measure of health literacy in our health system when compared to the bhls and short test of functional health literacy in adults administered by research personnel.21,28 the bhls item addressing confidence with forms was reverse scored , and the 3 responses were summed to generate a score between 3 and 15 , where higher scores indicated higher health literacy .
this threshold is based on our prior work and was chosen to maximize sensitivity and specificity for correctly classifying patients with low health literacy compared to the short test of functional health literacy in adults.29
the primary outcome was the time from hospital discharge to death , which was censored on december 31 , 2013 .
date of death was obtained from the social security death index ( ssdi ) and by extraction from the institution s ehr , which also contains clinical documentation of deaths .
of 403 identified deaths , 286 ( 71.0% ) were identified in both social security death index and ehr ; 64 ( 15.9% ) were identified by social security death index , and 53 ( 13.2% ) were identified in the ehr ( and confirmed by chart review ) . planned secondary outcomes
included time to the first rehospitalization and time to the first ed visit within 90  days of index hospital discharge .
date of rehospitalization and ed visits were identified by extraction from the ehr . only rehospitalizations and ed visits at the index medical center were identified .
covariates were chosen based on expected relationships with health literacy , death , or healthcare utilization .
the following covariates were recorded during the index hospitalization and extracted from the ehr : age , sex , race ( white , black , other ; by self - report),30 insurance ( private , state / federal , uninsured ) , and highest level of education .
hospital length of stay was computed by administrative time stamps , and comorbid conditions31 were measured by the elixhauser comorbidity index .
the elixhauser index includes 30 comorbid conditions and is associated with hospital length of stay , hospital charges , and mortality.32
the primary analysis tested the a priori hypothesis that patients with low health literacy had a shorter time / greater risk of the outcome of death after hospitalization for ahf .
cumulative incidence plots were constructed to visualize the relationship between health literacy level ( bhls 9 versus bhls > 9 ) and outcomes , and the log rank test was used to compare the survival distributions . adjusted analyses used a cox proportional hazards model to examine the relationships between health literacy and the primary outcome of time - to - death , adjusting for covariates age , sex , race , insurance status , education , index hospital length of stay , and the elixhauser comorbidity index .
the proportional hazards assumption was evaluated by log - log plots and tested using schoenfeld residuals.33 the same modeling approach was applied to the planned secondary outcomes of time - to - first rehospitalization and time - to - first ed visit within 90  days , in separate models .
first , we examined the relationship between health literacy and death across the range of health literacy thresholds . adjusted cox regression
was repeated for bhls dichotomized at a score of 14 ( bhls=15 , bhls < 15 ) and for continuous bhls with restricted cubic splines with 4 knots ( at 13 , 10 , 7 , and 4 ) .
second , we conducted stratified analyses by age ( < 65 , 65 ) , race ( white , nonwhite ) , education ( high school , less than high school ) , and length of stay for the index hospitalization ( 5  days , > 5  days ) .
third , patients could have multiple hospitalizations over the course of the study duration ; therefore , we evaluated rehospitalizations and ed visits using robust standard errors .
no adjustment was made for multiple analyses.34 analyses were conducted using stata 12.0 ( statacorp , college station , tx ) .
between november 1 , 2010 and june 30 , 2013 , there were 2132 patients hospitalized for ahf ; of these , 162 died in the hospital or had unknown hospital disposition and 251 were transferred to a care facility or hospice .
of the remaining 1719 patients , 245 had incomplete bhls and 95 were missing covariates , leaving 1379 who were discharged home and had complete bhls and demographic information ( figure 1 ) .
of these , 1055 ( 76.5% ) had a bhls > 9 , and 324 ( 23.5% ) had low health literacy ( bhls 9 ) . use of an interpreter was recorded for 33 patients ( 2.3% ) .
patient characteristics by health literacy status are found in table 1 ; analysis results are found in table 2 and table 3 .
patients with low health literacy were older and more likely to be male , insured by federal or state health insurance , and to have not completed high school .
characteristics of patients excluded from the analyses for missing bhls or covariates are shown in tabletable 4 .
characteristics of patients by bhls score bhls indicates brief health literacy screen ; iqr , interquartile range ; los , length of stay . adjusted cox regression analyses for outcomes : death , 90-day rehospitalization , and
90-day ed visit by bhls bhls indicates brief health literacy screen ; ed , emergency department ; hr , hazard ratio .
cox regression adjusted for age , gender , race , insurance , education , index hospitalization length of stay , and disease severity .
cox model demonstrates the hazard for the risk of the outcome among those with a bhls score 9 compared to those with a bhls score > 9 .
stratified analyses for mortality by subgroups bhls indicates brief health literacy screen ; hr , hazard ratio ; los , length of stay . cox regression adjusted for age , gender , race , insurance , education , index hospitalization length of stay , and disease severity .
cox model demonstrates the hazard for the risk of the outcome among those with a bhls score 9 compared to those with a bhls score > 9 .
patient characteristics among those with incomplete bhls , bhls 9 , and bhls > 9 bhls indicates brief health literacy screen ; hr , hazard ratio ; los , length of stay . kruskal  wallis or nonparametric test for trend , as appropriate .
cox regression for death by bhls > 9 , bhls 9 , incomplete bhls ; adjusted for age , gender , race , insurance , education , index hospitalization length of stay , and disease severity .
there were 403 ( 29.2% ) deaths during study follow - up ( table2 ) .
median follow - up was 20.7  months ( interquartile range 12.8 , 29.6  months ) .
of the 324 patients with bhls 9 , 124 ( 38.3% ) died , compared to 279 ( 26.5% ) deaths among the 1055 patients with bhls > 9 .
the median time to death was shorter for patients with bhls 9 than for patients with bhls > 9 ( log rank p<0.001 ) .
after adjusting for age , gender , race , insurance , highest level of education , hospital length of stay , and comorbid conditions , the risk of death for patients with bhls 9 was 32% higher than for patients with bhls > 9 ( ahr 1.32 ; 95% ci 1.05 , 1.66 , p=0.02 ) .
bhls indicates brief health literacy screen . during the 90-day follow - up after each hospitalization for ahf , 415 ( 30.1% ) patients
were rehospitalized and 201 ( 14.6% ) had an ed visit and were discharged home .
the average number of ed visits within 90  days per patient was 1.84 ( median 1 , interquartile range 0 , 2 ) .
there was no evident association of health literacy with time to first rehospitalization or ed visit ( table2 ) .
when we varied the threshold for low health literacy to a bhls score of < 15 , results were consistent with the main findings ( ahr=1.35 , 95% ci 1.08 , 1.69 ) . when bhls was modeled using restricted cubic splines , the hazard of death increased as bhls decreased ( figure 3 ) .
thus , the risk of death for each decreasing level of health literacy was as follows : ahr 1.23 ( 95% ci 1.03 , 1.47 ) , 1.43 ( 95% ci 1.11 , 1.85 ) , 1.48 ( 95% ci 1.14 , 1.91 ) , and 1.50 ( 95% ci 1.05 , 2.13 ) for bhls scores of 13 , 10 , 7 , and 4 , respectively . health literacy and association with mortality  restricted cubic splines .
adjusted for age , sex , race , insurance , education , index hospitalization length of stay , and disease severity .
there was no evidence for effect modification by age , race , education , and hospital length - of - stay , with interaction term p - values all larger than 0.05 , although relationships between literacy and mortality were statistically significant only among subgroups for subjects with age 65  years , nonwhite race , less than high school education , and index hospital length - of - stay 5  days ( table3 ) . allowing multiple hospitalizations did not change the results of analyses for rehospitalizations or ed visits .
compared to patients who completed all 3 bhls survey items , those with incomplete bhls were younger , more likely to be female , white , have private insurance , and have had a shorter hospital length of stay .
education level was missing for 220 ( 89.8% ) of these patients ; of the 25 patients with education available , none had completed high school ( table4 ) .
after adjustment for disease severity and comorbid conditions , there was no difference in mortality risk between those with incomplete and complete bhls ( ahr of death 0.73 , 95% ci 0.30 , 1.76 , table4 ) .
there were 403 ( 29.2% ) deaths during study follow - up ( table2 ) .
median follow - up was 20.7  months ( interquartile range 12.8 , 29.6  months ) .
of the 324 patients with bhls 9 , 124 ( 38.3% ) died , compared to 279 ( 26.5% ) deaths among the 1055 patients with bhls > 9 .
the median time to death was shorter for patients with bhls 9 than for patients with bhls > 9 ( log rank p<0.001 ) .
after adjusting for age , gender , race , insurance , highest level of education , hospital length of stay , and comorbid conditions , the risk of death for patients with bhls 9 was 32% higher than for patients with bhls > 9 ( ahr 1.32 ; 95% ci 1.05 , 1.66 , p=0.02 ) .
during the 90-day follow - up after each hospitalization for ahf , 415 ( 30.1% ) patients were rehospitalized and 201 ( 14.6% ) had an ed visit and were discharged home .
the average number of ed visits within 90  days per patient was 1.84 ( median 1 , interquartile range 0 , 2 ) .
there was no evident association of health literacy with time to first rehospitalization or ed visit ( table2 ) .
when we varied the threshold for low health literacy to a bhls score of < 15 , results were consistent with the main findings ( ahr=1.35 , 95% ci 1.08 , 1.69 ) .
when bhls was modeled using restricted cubic splines , the hazard of death increased as bhls decreased ( figure 3 ) .
thus , the risk of death for each decreasing level of health literacy was as follows : ahr 1.23 ( 95% ci 1.03 , 1.47 ) , 1.43 ( 95% ci 1.11 , 1.85 ) , 1.48 ( 95% ci 1.14 , 1.91 ) , and 1.50 ( 95% ci 1.05 , 2.13 ) for bhls scores of 13 , 10 , 7 , and 4 , respectively .
adjusted for age , sex , race , insurance , education , index hospitalization length of stay , and disease severity .
there was no evidence for effect modification by age , race , education , and hospital length - of - stay , with interaction term p - values all larger than 0.05 , although relationships between literacy and mortality were statistically significant only among subgroups for subjects with age 65  years , nonwhite race , less than high school education , and index hospital length - of - stay 5  days ( table3 ) . allowing multiple hospitalizations
there were 245 subjects excluded for incomplete bhls . compared to patients who completed all 3 bhls survey items ,
those with incomplete bhls were younger , more likely to be female , white , have private insurance , and have had a shorter hospital length of stay .
education level was missing for 220 ( 89.8% ) of these patients ; of the 25 patients with education available , none had completed high school ( table4 ) .
after adjustment for disease severity and comorbid conditions , there was no difference in mortality risk between those with incomplete and complete bhls ( ahr of death 0.73 , 95% ci 0.30 , 1.76 , table4 ) .
in this study of 1379 patients hospitalized for ahf , low health literacy was associated with increased risk of death ( ahr 1.32 , 95% ci 1.05 , 1.66 , p=0.02 ) after adjustment for education , age , sex , race , health insurance status , hospital length of stay , and comorbidities .
low health literacy , defined as bhls < 15 , bhls < 13 , or bhls 9 was associated with increased risk of mortality . taken together
, these results suggest that patients with anything less than optimal health literacy who are hospitalized for ahf may warrant additional health resources , assistance , discharge planning , or coordination of care to facilitate the transition from hospital to outpatient care in order to optimize long - term self - care of heart failure . in this study ,
the relationship between health literacy and mortality was not modified by age , race , or education .
our findings lend additional weight to the importance of health literacy and provide guidance for healthcare providers as they risk stratify patients hospitalized for ahf . in our healthcare system ,
results of the health literacy measure are available to all healthcare providers through the ehr , overcoming previous difficulties identifying patients with low health literacy16,17 ; in the future , this easy access to a reliable measure of health literacy may facilitate more accurate identification of and intervention for patients with heart failure to reduce the risk of death .
in general , low health literacy has been associated with multiple health outcomes , including death and healthcare utilization.19,35 self - care is recognized as a vital component of chronic heart failure management,10 which includes monitoring weight , salt intake , and fluid intake , and titrating diuretics ; these in turn may be related to health literacy and mortality .
however , the direct relationships among health literacy , self - care , and outcomes including mortality and healthcare utilization are not well understood.14,15 investigation regarding effective interventions to improve heart failure chronic self - care and patient - centered outcomes is ongoing.36 patient education alone has generally not been enough to improve outcomes.37 health literacy can influence chronic disease management .
healthcare providers often overestimate the health literacy skills of their patients.16,17 as a result , patients with unrecognized low health literacy may receive healthcare instructions and prescription regimens that are complex , difficult to understand and implement , limiting their ability to successfully achieve outpatient disease control .
these patients may also have difficulty communicating with healthcare providers , navigating the health care system , recognizing signs of health decline , and knowing when and who to contact when they do become ill .
low health literacy may influence mortality via disease self - management as well as unrecognized impact on outpatient disease management by healthcare providers . in analyses of 90-day rehospitalization and ed visits
these findings are consistent with work by peterson et  al,19 which was conducted among outpatients with heart failure in which the bhls was administered via mail ; in their study , low health literacy ( defined as bhls < 6 ) was found to predict all - cause mortality but not hospitalization .
we expand on these findings by showing that this association with mortality is also found among patients hospitalized for ahf and that the risk of death is borne by patients with bhls < 15 , not only those with bhls 9 or even bhls < 6 . although we did not find evidence for a relationship between low health literacy and ed visits or with rehospitalizations within 90  days
, the proportion of patients who were rehospitalized or had an ed visit is similar to those reported elsewhere.38 ed visits and rehospitalizations after ahf are multifactorial39,40 ; the relationship between health literacy and mortality among patients with heart failure may be independent of markers of healthcare utilization such as ed visits and rehospitalization .
in addition , a weak relationship with ed visits or rehospitalization may not have been detectable in the 90-day follow - up period , compared to the multiyear follow - up for mortality .
finally , we can not conclusively exclude a relationship between health literacy and rehospitalizations or ed visits because we were unable to include all rehospitalizations and ed visits to other hospitals .
health literacy was measured by the bhls , a 3-item survey administered by nursing staff at the time of hospitalization .
we have shown this method of administration to be a valid measure of health literacy compared to the short test of functional health literacy in adults.41 while patient self - report may increase the risk of social desirability bias , nondifferential misclassification of health literacy would underestimate the true risk of death.42 in a highly health - literate population , the bhls may be subject to a ceiling effect .
however , even in our population , in which 23.5% had low health literacy , we found that low health literacy was associated with increased risk of death .
analyses included adjustment for age , sex , race , health insurance , highest level of education , hospital length of stay , and comorbidities . despite this , it is possible that type of heart disease or other difficult - to - measure factors such as depression and patient frailty may have a residual influence on the relationship between health literacy and mortality
. we did not include medication changes and management decisions made after discharge from the hospital , as these may be part of the path between patient s health literacy and outcomes .
hospitalized patients with incomplete education or bhls may differ in their characteristics from those who with complete bhls information.43 we did not perform multiple imputation of the bhls for the 245 subjects with 1 or more bhls items missing due to the possibility that missingness may not have been random .
however , after adjusting for patient characteristics , we did not find a difference in the risk of death between patients with complete and those with incomplete bhls ( table4 ) . within the available data , we are unable to account for potential prior hospitalizations , cardiac events , or other indicators of disease severity such as ejection fraction , which have been shown to be associated with death8,44 and may be related to health literacy .
finally , we selected this population from patients hospitalized at a quaternary medical center for ahf .
while this population may not be reflective of all patients hospitalized with ahf , the methods for identifying patients hospitalized for ahf are standardized and widely used for quality metric reporting . as a result ,
our findings are likely to be generalizable to many patients hospitalized for ahf who have low health literacy .
in this retrospective study of patients discharged home after hospitalization for ahf , death , rehospitalization , and ed visits were common .
patients with a lower level of health literacy as measured by the bhls had an increased risk of all - cause death ; this risk rose with decreasing health literacy .
this suggests that additional measures to overcome barriers to effective long - term heart failure self - care may be needed among patients with any degree of low health literacy .
this research was supported by funding from the national heart , lung , and blood institute ( r21hl096581 , k12hl109109 , and ul1tr000445 ) .
dr storrow is a current consultant for roche diagnostics ; novartis pharmaceuticals corp , usa ; alere diagnostics ; trevena ; and beckman coulter .
 backgroundmore than 30% of patients hospitalized for heart failure are rehospitalized or die within 90  days of discharge . 
 lower health literacy is associated with mortality among outpatients with chronic heart failure ; little is known about this relationship after hospitalization for acute heart failure.methods and resultspatients hospitalized for acute heart failure and discharged home between november 2010 and june 2013 were followed through december 31 , 2013 . 
 nurses administered the brief health literacy screen at admission ; low health literacy was defined as brief health literacy screen 9 . 
 the primary outcome was all - cause mortality . 
 secondary outcomes were time to first rehospitalization and , separately , time to first emergency department visit within 90  days of discharge . 
 cox proportional hazards models determined their relationships with health literacy , adjusting for age , gender , race , insurance , education , comorbidity , and hospital length of stay . 
 for the 1379 patients , average age was 63.1  years , 566 ( 41.0% ) were female , and 324 ( 23.5% ) had low health literacy . 
 median follow - up was 20.7  months ( interquartile range 12.8 to 29.6  months ) , and 403 ( 29.2% ) patients died . 
 adjusted hazard ratio for death among patients with low health literacy was 1.34 ( 95% ci 1.04 , 1.73 , p=0.02 ) compared to brief health literacy screen > 9 . within 90  days of discharge , there were 415 ( 30.1% ) rehospitalizations and 201 ( 14.6% ) emergency department visits , with no evident association with health literacy.conclusionslower health literacy was associated with increased risk of death after hospitalization for acute heart failure . 
 there was no evident relationship between health literacy and 90-day rehospitalization or emergency department visits . 
Methods
Study Design, Setting, and Data Sources
Population
Patient-Reported Health Literacy
Outcomes: Death, 90-Day Rehospitalization, ED Visit
Covariates
Statistical Analysis
Sensitivity and Subgroup Analyses
Results
Primary Outcome: Hazard of Mortality by Health Literacy
Secondary Outcomes: Rehospitalization, ED Visits Within 90Days
Sensitivity and Subgroup Analysis
Incomplete BHLS
Discussion
Conclusions
Sources of Funding
Disclosures