class ii malocclusion can be appraised as skeletal and dental class ii.1 the treatment of skeletal class ii malocclusion in non - growing individuals involves either surgical correction of the jaw abnormality , or orthodontic camouflage which usually requires the extraction of premolars or distal movement of the maxillary molars.23 for several years , extraoral appliances such as headgear were the most widely used distalizing appliances , but they are not esthetically desirable or socially acceptable , especially for adults .
they are also removable and require patient compliance , which can compromise the results.4 several intraoral noncompliance devices for maxillary molar distalization have been recommended since the 1980s.5 these include but are not limited to the hilgers pendulum appliance , jones jig distalization apparatus , open nickel - titanium ( niti ) push coils , distal jet , repelling magnets , and molar slider.67891011 numerous side effects have been reported in association with these tooth - borne distalizing appliances , including anchorage loss of the maxillary premolars and flaring of the incisors , and a significant amount of relapse can occur .
also , the distalized molars must be used for anchorage during retraction of the premolars and anterior teeth,5 resulting in a bite - opening effect that is not tolerable for most patients . temporary anchorage devices ( tads ) have been investigated , in an effort to overcome some of the side effects associated with tooth - borne distalizing appliances.1 dental implants , miniscrews , and miniplates have been used for skeletal anchorage.11112131415 tads have several advantages .
they are relatively easy to place , inflict less trauma on the oral tissues , are stable under normal degrees of force , and can bear force immediately after placement .
miniscrews , in particular , are relatively inexpensive and patient compliance is limited to maintaining good oral hygiene .
given their small size , they can be inserted in a variety of sites on the alveolar and basal bones.316171819 however , they have been associated with damage to anatomical structures such as dental roots , nerves , and blood vessels , and there are the possibilities of screw breakage on placement and removal , and screw failure with peri - implant inflammation .
the reported success rates of miniscrews range from 80% to 95%.20 the placement of miniscrews in the buccal interradicular bone is one of the most common approaches used to provide skeletal anchorage .
the interradicular space is a potentially advantageous region for insertion , because there is less potential for complications related to soft tissue irritation , particularly if they are placed through the attached gingiva.20 although adjacent teeth may limit mesiodistal tooth movement , buccal interdental miniscrews are very useful for molar distalization , due to their ease of placement , and simple application during treatment . with a properly positioned tad
, 3 mm of distal movement per side can be achieved.21 on the palatal side , a tad may be placed paramedian ( near the midline ) or in the interdental space . while paramedian appliances usually require more expensive and sophisticated attachments , the risk of root damage associated with them is minimal.161222 tads placed on the palatal interdental area can apply distalization forces directly to the molar .
moreover , these tads can also control the mesiodistal axis of the molar via manipulation of the line of action.22 we have introduced a new appliance using palatal miniscrews " mimi - implant - aided ( mia ) in the interdental area between the 1st molar and 2nd premolar root and a trans - palatal arch ( tpa ) to overcome some of the mechanical shortcomings of previous appliances , in contexts including anterior protrusion , extrusion of posterior teeth , and tipping of molar teeth ( mia - tpa ) .
traction between tads in the palatal interdental area and a tpa can produce direct distalization force that travels through the center of resistance of molars ( figure 1 ) .
the purpose of the present study was to measure the three - dimensional ( 3d ) movement of 1st molars after using this newly designed distalizing appliance .
the sample group consisted of 26 patients ( 22 females , 4 males ) with an average age of 19.8  6.3 years ( range 12 - 36 years ) at the beginning of treatment ( table 1 ) .
the main inclusion criterion was angle class ii malocclusion of no more than one cusp on each side .
patients with missing teeth , substantial restorations , or any craniofacial malformation were excluded from the study .
the study was approved by the university research and ethics committee , and registered as a clinical trial at iranian registry of clinical trials ( no .
irct201302269085n3 ) . all patients ( and their parents in the case of minors ) were informed about the treatment procedures involved , and informed consent was provided . after preparing the initial diagnostic records including dental casts , a dentist placed two miniscrews , each with a range of 8 - 10 mm in length and 1.4 , 1.6 , or 2.0 mm in diameter in the palatal interdental area under local anesthesia .
miniscrews were inserted between maxillary 2nd premolars and 1st molars with a self - tapping technique , approximately 5 - 6 mm from the gingival crest at an angle of 60 - 80 relative to the long axis of adjacent teeth .
the heads of the screws were approximately 2 mm above the mucosal surface , to facilitate the attachment of elastic modules .
a tpa was made on a cast with stainless steel wire of 0.8 mm in diameter , with two helices or hooks soldered into the lateral incisors area .
miniscrews were loaded with an average force of 150 - 200 gram - force / side via elastic modules , and ligature wire was used to connect the tpa , almost parallel to the occlusal plane of the miniscrew .
all of the other teeth were bonded from 2nd molar to 2nd molar with standard edgewise brackets and tubes ( dentaurum , ispringen , germany ) , and leveling and aligning were performed before the termination of distalization to reduce any possible anchorage loss after distalization .
the final arch wire was 0.018-in stainless steel . a cone - beam computed tomography ( cbct ) scan ( newtom 3 g ; quantitative radiology , verona , italy ) was performed to evaluate the precise position of mini screws relative to adjacent teeth and the direction of the force relative to molar teeth .
after maxillary 1st molars were driven to super class i relationship , distalization was terminated and a final impression was taken for final evaluation .
digital model analysis of molars was used to evaluate changes in the 3d position of the maxillary molars .
digital scans of models before and after distalization were prepared via a maestro 3d dental scanner ( age solutions s.r.l . ,
maestro ortho studio software version 2.5 ( age solutions s.r.l . ) was used to analyze the digital models .
the palatal rugae possesses unique characteristics , and as it tends to exhibit reasonable stability during growth , it may serve as a suitable reference point for longitudinal cast analysis.23 as the patients in the current study were not in an active growth period and no potential incisor movement was anticipated during the distalization period , as in nalcaci et al.,1 the distance from the central point of the incisive papilla to the mesiopalatal cusp of the 1st maxillary molars was used to measure distalization .
the distances between the mesiopalatal cusps of the left and right molars were measured to evaluate intermolar width .
the angles between the incisive papilla and the distopalatal and mesiobuccal cusps of the 1st maxillary molars were measured to evaluate the rotation of maxillary molars1 ( figure 2 ) .
interocclusal space at the mesiobuccal , distobuccal , and mesiopalatal cusps of the 1st maxillary molars was evaluated by occlusion inspection , and maestro 3d scanner and software was used to evaluate vertical movement . after putting the casts in the maximum intercuspal position ,
the spaces between the maxillary 1st molar cusps and the antagonist tooth at t1 and t2 were measured via a 0.5-mm interval scale with a color coded tool ( figure 3 ) . for cbct analysis
, digital imaging and communications in medicine ( dicom ) files were imported to a dolphin 3d 11 ( dolphin imaging , chatsworth , ca , usa ) .
the angle between this line and a line drawn parallel to the occlusal plane was measured on right and left 3d sagittal view . in 3d axial view , lines between the helix and the miniscrews on the right and left sides were drawn , and the angle between those lines ( axial angle ) was measured ( figure 4 ) .
measurements were repeated one month after the initial measurements , and the reliability of the measurements was calculated via the intraclass correlation test .
reliability was between 79.7 and 97.0 for linear measurements , and between 93.8 and 96.6 for angular measurements .
the paired t - test was used to compare measurements acquired before and after distalization in a digital cast . a probability of p < 0.05 was deemed to indicate statistical significance .
pearson 's correlation was used to evaluate the relationships between cbct parameters and digital cast parameters . statistical package for the social sciences ver . 13.0 ( spss inc . ,
the palatal rugae possesses unique characteristics , and as it tends to exhibit reasonable stability during growth , it may serve as a suitable reference point for longitudinal cast analysis.23 as the patients in the current study were not in an active growth period and no potential incisor movement was anticipated during the distalization period , as in nalcaci et al.,1 the distance from the central point of the incisive papilla to the mesiopalatal cusp of the 1st maxillary molars was used to measure distalization .
the distances between the mesiopalatal cusps of the left and right molars were measured to evaluate intermolar width .
the angles between the incisive papilla and the distopalatal and mesiobuccal cusps of the 1st maxillary molars were measured to evaluate the rotation of maxillary molars1 ( figure 2 ) .
interocclusal space at the mesiobuccal , distobuccal , and mesiopalatal cusps of the 1st maxillary molars was evaluated by occlusion inspection , and maestro 3d scanner and software was used to evaluate vertical movement . after putting the casts in the maximum intercuspal position ,
the spaces between the maxillary 1st molar cusps and the antagonist tooth at t1 and t2 were measured via a 0.5-mm interval scale with a color coded tool ( figure 3 ) . for cbct analysis
, digital imaging and communications in medicine ( dicom ) files were imported to a dolphin 3d 11 ( dolphin imaging , chatsworth , ca , usa ) .
the angle between this line and a line drawn parallel to the occlusal plane was measured on right and left 3d sagittal view . in 3d axial view , lines between the helix and the miniscrews on the right and left sides were drawn , and the angle between those lines ( axial angle ) was measured ( figure 4 ) .
measurements were repeated one month after the initial measurements , and the reliability of the measurements was calculated via the intraclass correlation test .
reliability was between 79.7 and 97.0 for linear measurements , and between 93.8 and 96.6 for angular measurements .
the paired t - test was used to compare measurements acquired before and after distalization in a digital cast . a probability of p < 0.05 was deemed to indicate statistical significance .
pearson 's correlation was used to evaluate the relationships between cbct parameters and digital cast parameters . statistical package for the social sciences ver . 13.0 ( spss inc . ,
maxillary 1st molars were moved distally an average of 2.3  1.1 mm , and the difference between the right and left sides was not statistically significant ( p = 0.63 ) .
the mean duration of distalization was 6.8  2.8 months ( range 2 - 14 months ) , thus the average rate of distalization achieved via the method utilized in the current study was 0.4  0.2 mm / month .
maxillary 1st molars were slightly rotated mesially around the palatal root after distalization , though the amount of rotation was not statistically significant ( this rotation is shown with a minus sign in table 2 ) .
the mean intermolar width increase was 2.9  1.8 mm ( range 0.6 - 6.8 mm ) .
the examination of vertical movement of three cusps of the maxillary molars showed relative molar intrusion that was statistically significant , except in the left mesiopalatal cusp ( table 2 ) .
orthodontists are frequently faced with mild to moderate class ii molar and canine relationships that they prefer not to treat via the extraction of premolars , and for which treatment via auxiliary methods is often unsatisfactory due to insufficient patient compliance .
many studies on intraoral maxillary molar distalization without patient cooperation have been performed , in order to solve the patient compliance problem associated with extraoral distalization appliances.110111220222425262728 in the present study , maxillary 1st molars were distalized via mini - implant - aided tpa . in mia - tpa ,
direct traction from elastic modules spanning from a miniscrew to a tpa helix is used to achieve molar distalization .
miniscrews were inserted into the palate in this study , wherein attached gingiva is not a major concern , in contrast to the buccal side .
moreover , there is more interdental space in the palate relative to the buccal side , and larger miniscrews ( 2 mm in diameter ) can be inserted . in the present study ,
the mesiodistal axis of molar movement can be controlled by adjusting the vertical position of miniscrews and/or the direction of the line of action relative to furcation .
thus , bodily tooth movement is promoted , rather than tipping movement . in the current study ,
a removable tpa was used which made possible both proper adjustment of the line of action , and the control of molar rotation .
the appliance is of a reduced size relative to other similar devices , and was tolerated by all of our patients without any concerns .
there were also no problems reported with regard to the maintenance of oral hygiene . in the treatment protocol used in the current study ,
the elastic properties of the modules were lost relatively quickly in the oral cavity however , so the force applied was intermittent in nature , and they needed to be changed at least every 3 weeks . while niti pull coils allow for the application of more continuous force for distalization , they require a distance of at least 20 mm between the miniscrew and helix , to produce an appropriate level of force . in this study ,
3d models were used for the 3d analysis of maxillary molar movements . two - dimensional ( 2d ) analysis by superimposing pretreatment and posttreatment cephalometric tracings has commonly been used in orthodontic studies.26 there are some disadvantages of cephalometric radiographs and superimpositions .
the superimposition of lateral cephalograms is not easily accomplished , because the relevant radiographic landmarks and structures are frequently difficult to accurately trace .
also , the process of superimposing can be technique - sensitive.29 cephalometric superimposition can reveal positional changes in the maxillary and mandibular dentition in both vertical and sagittal dimensions , but not in the buccopalatal direction .
in contrast to 2d analysis , 3d analysis of serial dental models can provide further information on tooth movements , particularly in the buccolingual or transverse direction .
the projection of bilateral teeth on the midsagittal plane also causes greater tracing errors because of the difficulty in identifying the bilateral teeth .
consequently , the separate investigation of the tooth movements on each side , which can be achieved relatively easily via 3d models , is seldom attempted via cephalometric analysis.26 in this study , the distal movement of molars was measured along the line connecting the central point of the incisive papilla and the mesiolingual cusp of the 1st molar . while this measurement does not reflect true distal movement , measuring
the intermolar change can provide a clear determination of both the distal and buccal movement of maxillary molars according to best available anatomical reference points . applying a distal force to maxillary molars moved them in three dimensions . with the device used in the current study
, maxillary 1st molars were distalized 2.3  1.1 mm . in other studies based on intraosseous anchorage appliances ,
distalization was between 1.3 and 6.4 mm.110202224262728 distalization was higher in studies that used tooth - borne appliances such as pendulums or dual force distalizers supported by mini - implants for molar distalization.222527 the main reasons for the reduced distal movement of maxillary molars in our study were related to characteristics of our sample .
the majority of patients in our sample required less than one cusp of distal movement .
nalcaci et al.1 distalized molars via miniscrews with open coil springs by an average 3.95  1.35 mm .
gelgr et al.10 distalized molars by an average 3.9  1.6 mm via screws supported by tpas and niti open coil springs .
yamada et al.20 used miniscrews and elastomeric chain or niti closed coils for distalization , and average molar movement was 2.8  1.6 mm .
the mean duration of distalization in our study was 6.8  2.8 months , thus the rate of distalization was 0.4  0.2 mm / month .
in other studies , the duration of distalization was between 4.5 and 10.2 months.11020222425262728 nalcaci et al.1 reported an average duration of 9.61  2.1 months , and a rate of 0.41 mm / month .
yamada et al.20 reported a duration of 8.4 months and a rate of 0.33 mm / month . in this study , mean maxillary 1st molar rotation was -0.86  4.6 and -0.35  4.1 in the right and left sides respectively .
nalcaci et al.1 reported 0.54 and 0.74 rotation in the right and left sides respectively .
buccal movement of molars was evident in the current study , with a mean increase of 2.9  1.8 mm in intermolar width .
many studies1112224 reported buccal movement of molars , while yamada et al.,20 and lai et al.,26 reported palatal movement of molars .
tpas made up of 0.8 mm round stainless steel wire do not have enough strength to resist expansion due to distal traction force .
intrusion was the hallmark of this appliance , and numerous authors reported intrusion of molars in their studies.1222425 in a study similar to the current study , maxillary molars were intruded by an average of 0.3  0.8 mm.1 on the other hand , yamada et al.20 and lai et al.26 reported extrusion of molars . in the majority of our cases , the line of action of force passed through the furcation and the center of resistance of molars in an apical direction ,
concomitant intrusion of 2nd molars and premolars could be masked by mandibular overclosure , if present at all .
so , we did not measure absolute intrusion via this type of measurement , instead interocclusal discrepancy was measured .
the absolute measurement of intrusion is more accurately achieved via cbct before and after distalization . however , a second cbct was not approved by the relevant research ethics committee .
two miniscrews of 1.4  8.0 mm inserted in the same patient failed in the current study . they were found to be loose at the first visit after fitting .
larger miniscrews ( 2.0  10.0 mm ) were then inserted in this patient , but these also became loose so the patient was removed from the study . among the remaining patients , 3 screws ( 5.7% ) became loose . in these cases ,
excessive contact between the tpa and the miniscrew was the probable cause of screw failure in these cases .
the mia - tpa is an appliance that can achieve absolute anchorage , and successfully drive maxillary 1st molars distally .
 objectivethe aim of this study was to investigate three - dimensional molar displacement after distalization via miniscrews and a horizontal modification of the trans - palatal - arch ( tpa).methodsthe subjects in this clinical trial were 26 class ii patients . 
 after the preparation of a complete set of diagnostic records , miniscrews were inserted between the maxillary 2nd premolar and 1st molar on the palatal side . 
 elastic modules connected to the tpa exerting an average force of 150 - 200 g / side parallel to the occlusal plane were applied . 
 cone - beam computed tomography was utilized to evaluate the position of the miniscrews relative to the adjacent teeth and maxillary sinus , and the direction of force relative to molar furcation . 
 the distances from the central point of the incisive papilla to the mesiopalatal cusps of the 1st maxillary molars and the distances between the mesiopalatal cusps of the left and right molars were measured to evaluate displacement of the maxillary molars on the horizontal plane . 
 interocclusal space was used to evaluate vertical changes.resultsmean maxillary 1st molar distalization was 2.3  1.1 mm , at a rate of 0.4  0.2 mm / month , and rotation was not significant . 
 intermolar width increased by 2.9  1.8 mm . 
 molars were intruded relative to the neighboring teeth , from 0.1 to 0.8 mm.conclusionsdistalization of molars was possible without extrusion , using the appliance investigated . 
 the intrusive component of force reduced the rate of distal movement . 
INTRODUCTION
MATERIALS AND METHODS
3D digital model and CBCT analysis
Statistical analysis
RESULTS
DISCUSSION
CONCLUSION