the increase in frequency of arrhythmias and in symptoms during pregnancy may be a result of the associated hemodynamic , hormonal , autonomic , and emotional changes .
we report a patient who developed bradycardia followed by atypical wenckebach block , after subarachnoid block for cesarean section .
a 150 cm , 58 kg , 28-year - old second gravida , with history of previous lscs , presented with full term pregnancy with twins with transverse lie for lscs .
electrocardiography ( ecg ) , non - invasive blood pressure , and pulse oximetry monitoring was started .
subarachnoid block was given through the l3 - 4 intervertebral space with 10 mg 0.5% hyperbaric bupivacaine using 25-g whitacre pencil point spinal needle .
five minutes after the spinal injection , when the level of analgesia was t5 , ecg showed sinus bradycardia of 48/min and a prolonged pr interval followed by atypical wenckebach atrio - ventricular ( av ) block [ figures 1 and 2 ] .
bradycardia following spinal blockade atypical wenckabach block one healthy male and one female infant , with normal neurologic status , were delivered .
approximately two hours after the initiation of the spinal anaesthetic , ecg again showed progressive prolongation of the p - r interval in an atypical wenckebach type heart block [ figures 3 and 4 ] .
bradycardia two hours following spinal blockade atypical wenckabach block seen postoperatively echocardiograph showed normal sized cardiac chambers with no regional wall motion abnormality , global ejection fraction of 63% , no diastolic left ventricular dysfunction , and normal right ventricle systolic function .
valves were structurally normal and no other intra - cardiac defect , intra - cardiac mass or pericardial effusion was seen .
direct physiological effects of hormones , changes in autonomic tone , hemodynamic alterations , and hypokalemia of pregnancy can potentially result in arrhythmias during pregnancy , labour , and delivery .
intraoperative arrhythmias could be due to parasympathetic over - activity following chemical sympathectomy resulting from subarachnoid block due to a reduction in venous return , and subsequent to a vasovagal attack .
surgical maneuvers , like externalizing the uterus , also can result in increased vagal tone and cause arrhythmia . decreased threshold for cardiotoxicity with bupivacaine during pregnancy due to the increased unbound bupivacaine present in the hypoproteinemia of pregnancy or to the selective cardiac depressant effects of progesterone combined with bupivacaine
can also precipitate arrhythmia . in patients undergoing cesarean section under subarachnoid block , shen et al .
found the incidence of second degree av block to be 3.5% , and that of severe bradycardia ( heart rate < 50 beatsbullmin1 ) to be 6.7% .
mobitz i second - degree av block ( wenckebach block ) consists of progressive lengthening of conduction time in any cardiac tissue ( most often the av node or junction ) with ultimate dropping of a beat .
it usually occurs due to excess vagal tone and the site of the block is within the av node .
mobitz ii second - degree av block , is generally caused by conduction block in the his bundle or lower in the conduction system .
when mobitz type ii block is associated with a wide qrs complex , it is due to disease of the his - purkinje system .
these patients have a greater mortality and definite measures such as pacemaker insertion are needed to stop progression of the av block .
second - degree av block whether mobitz type ii or atypical wenckebach ( pseudo mobitz type ii ) is usually asymptomatic . however , some patients may complain of presyncope or syncope .
the latter is observed in more advanced conduction disturbances such as mobitz ii av block .
a history of intake of medications that alter av node function ( digitalis , beta - blockers , calcium channel blockers ) should be taken .
levels of electrolytes should be assessed in the case of second - degree av block whenever increased potassium levels are suspected .
the patient was classified as atypical wenckebach block , as she failed to meet one or more criteria for typical wenckebach periodicity .
typical wenckebach periodicity ( wenckebach and winterberg ) is considered to be present when : first pr interval of a cycle is the shortest ; there is progressive lengthening of the pr interval with the increment between the first and second conducted beats being the largest ; and there is progressive decrease in the rr intervals . a significant electrocardiographic difference between an atypical wenckebach block ( pseudo - mobitz ii arrangement ) in the av node and his - purkinje system is the length of the pr interval in the opening beat of the wenckebach cycle . in av
nodal block it usually remains significantly prolonged ( 026 to 038 s , with an average of 032 s ) .
mobitz type ii second - degree av block and a wide qrs complex indicate diffuse conduction system disease and is an indication for pacing , even in the absence of symptoms as it may degenerate into third - degree heart block .
shen et al . found that when patients had narrow qrs complexes with second degree av block and it occurred transiently during spinal anesthesia , the prognosis was benign .
our patient had atypical wenckebach block with narrow qrs complexes but it was transient and hence benign .
the bradycardia was due to parasympathetic over activity , which initiated the second degree heart block .
our patient did not have any hypotension , as reported by others , possibly because the patient was volume loaded . however , the arrhythmia recurred postoperatively when all surgical stimulation had been removed .
second - degree av block associated with symptomatic bradycardia is an indication for pacing . in asymptomatic patients with second - degree av block ,
type i with a narrow qrs complex , cardiac pacing may be required if the level of block is infranodal as found on electrophysiological studies , because the progression to complete heart block is common .
sympathetic block is slower to regress than the sensory block , and considerable sympathetic blockade can persist , when the patient is in the postoperative recovery .
atropine is contraindicated though it improves conduction in the av node minimally it increases the sinus rate markedly .
this can enhance the degree of block due to an increase in atrial rate . to conclude ,
we successfully managed a patient who developed bradycardia followed by atypical wenckebach block , after subarachnoid block for cesarean section .
 arrhythmias in pregnancy are common and may cause concern for the well - being of both mother and fetus . generally , no previous history of heart disease is elicited and majority of the arrhythmias are benign . 
 bradycardia is commonly seen following subarachnoid block for cesarean section . 
 however , the incidence of subsequent heart block is low . 
 this case report highlights the occurrence of perioperative arrhythmias following sympathetic blockade in pregnant patients and their early detection by vigilant monitoring . 
Introduction
Case Report
Discussion