e - cadherin immunohistochemistry in foci of subpleural lipogranulomatous inflammation shows positive staining only in pneumocytes .
 a 9-year - old , female , spayed , domestic longhaired cat presented to the ohio state university veterinary medical center oncology service with a 6-month history of changes in behavior and weight loss . the owner reported that the cat had become abnormally unfriendly and would growl or hiss when touched . 
 the cat also had gait changes , manifested by left hind limb weakness , difficulty walking up stairs , and occasionally losing balance and falling down stairs . 
 the cat was examined by its regular veterinarian and had abdominal radiographs , cbc , and biochemistry profile performed , which did not detect any abnormalities . on physical examination , 
 the cat was underweight with an estimated body condition score ( bcs ) of 1/5 . 
 neurologic examination revealed a very dull mentation , severe generalized muscle atrophy , and a slow , reluctant , and crouched gait . 
 cranial nerve examination revealed no abnormalities . 
 there was absence of conscious proprioception in all limbs . 
 a forebrain lesion was suspected . 
 the cat was examined 8 days later because of progressive signs of neurologic disease . 
 the cat was obtunded and had a right head turn with a mild right head tilt . 
 the gait showed proprioceptive / right vestibular ataxia with knuckling of both thoracic limbs on ambulation , a crouched posture , and a splaying outward of the left thoracic limb . 
 there was a decreased menace response bilaterally that was worse on the left and decreased nasal sensation bilaterally . 
 spinal reflexes were normal in all limbs . 
 neurolocalization was to the right - forebrain with possible brainstem involvement . 
 an abdominal ultrasound was then performed at the owner s request to investigate the gastrointestinal tract as a possible explanation for the weight loss , but no abnormalities were identified . 
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