 the collected comments and pathologic diagnoses of several pathologists are summarized for 18 cases in which lesions were induced in the upper respiratory tract of rats and mice . 
 specific neoplastic and nonneoplastic lesions of the nose and trachea are described and discussed , and opinions regarding pathogenesis and biologic significance of the lesions are presented . 
 the anatomic and pathophysiologic complexities of the rodent nose in relation to lesion development following inhalation or systemic exposure to xenobiotics are important considerations in the genesis of pathologic changes in this organ.imagesplate 1.plate 2.plate 3.plate 4.plate 5.plate 6.plate 7.plate 8.plate 9.plate 10.plate 11.plate 12.plate 13.plate 14.plate 15.plate 16.plate 17plate 18plate 19plate 20.plate 21.plate 22.plate 23.plate 24.plate 25.plate 26.plate 27.plate 28.plate 29.plate 30.plate 31.plate 32.plate 33.plate 34.plate 35.plate 36.plate 37.plate 38.plate 39.plate 40.plate 41.plate 42.plate 43.plate 44.plate 45.plate 46.plate 47.plate 48.plate 49.plate 50.plate 51.plate 52.plate 53 . 
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