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distal podomeres detach from tp of tc , and their presence guides the elongation and migration of tp belonging to other tc , as preliminary stages in the formation of a complex multi - cellular network . for supplementary materials on tc , please see http://www.telocytes.com .
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 abstracttelocytes ( tc ) are interstitial cells with telopodes ( tp ) . 
 these prolongations ( tp ) are quite unique : very long ( several tens of micrometres ) and very thin ( 0.5 m ) , with moniliform aspect : thin segments ( podomeres ) alternating with dilations ( podoms ) . to avoid any confusion , tc were previously named interstitial cajal - like cells ( iclc ) . 
 myocardial tc were repeatedly documented by electron microscopy , immunohistochemistry and immunofluorescence . 
 tc form a network by their tp , either in situ or in vitro . cardiac tc are ( completely ) different of  classic fibroblasts or fibrocytes . 
 we hereby present a synopsis of monitoring , by time - lapse videomicroscopy , of tp network development in cell culture . 
 we used a protocol that favoured interstitial cell selection from adult mouse myocardium . 
 videomicroscopy showed dynamic interactions of neighbour tc during the network formation . during their movement , 
 tc leave behind distal segments ( podomeres ) of their tp as guiding marks for the neighbouring cells to follow during network rearrangement . 
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