diabetes is a common chronic disease that is characterized by impaired insulin secretion and insulin resistance .
psychiatric disorders frequently occur in type 2 dm patients and about 15% of the diabetic patients are susceptible to depression . in iranian traditional medicine ( itm )
, the relationship between diabetes and depression is mentioned and special attention to their psychiatric problems is considered in the treatment of diabetes .
this study is a descriptive review according to available iranian traditional medicine literature such as canon compared with modern medicine by using pubmed and scopus databases .
in itm , diabetes is divided into warm and cold categories where the warm type is more common .
emotions such as anger and grief can play an important role in creating the warm or cold diabetes , respectively . in modern medicine
, several studies found that the odds of depression in the diabetic group were more than the non - diabetic comparison group . on the other hand ,
depression may have a role in the pathogenesis of dm with stimulation of the hypothalamic 
pituitary  adrenal axis , which results in increased cortical level and blood glucose , eventually progressing to diabetes .
evidence in modern medicine suggests that diabetes and depression can be a risk or exacerbating factor to each other . in itm ,
the theory of association between depression and diabetes is more highlighted than modern medicine , which is mentioned since more than 1000 years ago .
it seems that emphasis on the treatment of depression in diabetic patients may have significant effects in the course of their disease .
 background : diabetes is a common chronic disease that is characterized by impaired insulin secretion and insulin resistance . it is considered an urgent public - health issue because of its epidemic perspective . 
 depression is a highly prevalent disease with a lifetime prevalence of 17% . 
 individuals with depression experience reduced functioning and decreased quality of life . 
 psychiatric disorders frequently occur in type 2 dm patients and about 15% of the diabetic patients are susceptible to depression . in iranian traditional medicine ( itm ) , 
 the relationship between diabetes and depression is mentioned and special attention to their psychiatric problems is considered in the treatment of diabetes.methods:this study is a descriptive review according to available iranian traditional medicine literature such as canon compared with modern medicine by using pubmed and scopus databases.results:in itm , diabetes is divided into warm and cold categories where the warm type is more common . 
 emotions such as anger and grief can play an important role in creating the warm or cold diabetes , respectively.in modern medicine , several studies found that the odds of depression in the diabetic group were more than the non - diabetic comparison group . on the other hand , 
 depressed mood was associated with an increase of developing type 2 diabetes . 
 depression may have a role in the pathogenesis of dm with stimulation of the hypothalamic  
 pituitary  adrenal axis , which results in increased cortical level and blood glucose , eventually progressing to diabetes.conclusion:evidence in modern medicine suggests that diabetes and depression can be a risk or exacerbating factor to each other . in itm , 
 the theory of association between depression and diabetes is more highlighted than modern medicine , which is mentioned since more than 1000 years ago . 
 it seems that emphasis on the treatment of depression in diabetic patients may have significant effects in the course of their disease . 
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