. advanced laparoscopic procedures are increasingly being utilized as an alternative for laparotomy in gynecologic surgery .
a metaanalysis of 27 prospective randomized trials has proven the benefits of laparoscopic - assisted vaginal hysterectomy ( lavh ) compared with abdominal hysterectomy ( ah ) : decreased pain , decreased surgicalsite infections ( decreased relative risk 80% ) , decreased hospital stay ( 2 days less ) , quicker return to activity ( 2 weeks sooner ) , and fewer postoperative adhesions ( decreased 60% ) . in a cost - effectiveness analysis of lavh versus ah for large uteri ,
current procedural terminology ( cpt ) codes characterize large uteri as uteri > 250 g , ( 4 times normal uterine weight ) .
several authors have described the use of lavh for uteri weighing 500 g. however , no authors have looked specifically at the use of lavh for uteri weighing 1000 .
the purpose of this study was to evaluate the safety and efficacy of lavh performed for uteri weighing 1000 g.
fifteen patients underwent attempted lavh for uteri > 1000 g. patients were identified through the senior author 's surgical log from january 2005 to may 2007 .
all patients requiring surgery for large leiomyoma 's were offered lavh ; no patients refused lavh , and no patients were excluded .
institutional review board approval was obtained , and a retrospective computerized chart review was performed .
a single lavh was converted to laparotomy due to extensive pelvic adhesions , and the patient and surgical characteristics were not included .
a minimally invasive , academic gynecological oncologist from our minimally invasive surgical institute performed all cases , assisted by a senior gynecologic resident and a junior gynecologic resident or medical student .
all patients received a preoperative bowel prep with 45 ml of fleets phosphosoda orally , a single dose of preoperative prophylactic antibiotics and external pneumatic cuffs .
on postoperative day 1 , patients were given bowel stimulation with 45 ml of fleets phosphosoda , started on a general diet , and were discharged when fluid intake was adequate .
all procedures were performed with the patient under general endotracheal anesthesia . an orogastric tube was inserted and removed at the end of surgery .
the patient was positioned in the dorsolithotomy position with legs in allen stirrups , and placed in a maximal trendelenburg position ( 30 ) .
a gel pad was placed under the buttocks to prevent the patient from gravitating towards the head of the table .
a 5-mm trocar was inserted in the supraumbilical or left upper quadrant ( depending on uterus size , previous abdominal / pelvic incisions , and body habitus ) following veress needle pneumoinsufflation .
two additional 5-mm ports were placed in the right and left side , the position depending on the size and shape of the uterus .
it is essential to place an adequate number of ports to allow maximum uterine manipulation out of the pelvis and medial off of the pelvic side wall .
typically , a vaginal manipulator and 3 laparoscopic graspers are used to manipulate the uterus .
one grasper is applied to the contralateral round ligament , and 2 graspers are used as fulcrums ( figure 1 ) .
round ligaments were excised with the plasmakinetic cutting forceps ( gyrus acmi , southborough , ma ) .
retroperitoneal spaces were dissected , both ureters were identified , and the infundibulopelvic ligaments or ovarian ligaments / fallopian tubes ( depending on patient 's preference for ovarian conservation ) were excised with the pk cutting forceps . the anterior and posterior leaf of the broad ligament was dissected . using multiple laparoscopic graspers and the vaginal uterine manipulator , the uterus
after the uterus had been manipulated out of the pelvis , the bladder was dissected off the cervix with monopolar electrosurgery .
because of the enlarged size of the uterine vessels , the vessels were coagulated on the uterus prior to the standard coagulating and cutting .
all attempts were made to excise the cardinal and uterosacral ligaments with the pk cutting forceps .
the remainder of the uterosacral ligament was cut and suture ligated with 0 polyglycolic acid sutures .
pain assessment was evaluated using the visual analog scoring system : 0 - no pain , 2  mild pain , 5  moderated pain , 7  severe pain , and 10  excruciating pain . at our institution , visual analog scoring is performed and recorded every 4 hours by the nursing staff .
the highest visual analog score on postoperative day 0 or postoperative day 1 were used .
all patients were evaluated by the same nursing staff and had the same preprinted postoperative pain management protocol .
all patients received a preoperative bowel prep with 45 ml of fleets phosphosoda orally , a single dose of preoperative prophylactic antibiotics and external pneumatic cuffs . on postoperative day 1 , patients were given bowel stimulation with 45 ml of fleets phosphosoda , started on a general diet , and were discharged when fluid intake was adequate .
all procedures were performed with the patient under general endotracheal anesthesia . an orogastric tube was inserted and removed at the end of surgery .
the patient was positioned in the dorsolithotomy position with legs in allen stirrups , and placed in a maximal trendelenburg position ( 30 ) .
a gel pad was placed under the buttocks to prevent the patient from gravitating towards the head of the table .
a 5-mm trocar was inserted in the supraumbilical or left upper quadrant ( depending on uterus size , previous abdominal / pelvic incisions , and body habitus ) following veress needle pneumoinsufflation .
two additional 5-mm ports were placed in the right and left side , the position depending on the size and shape of the uterus .
it is essential to place an adequate number of ports to allow maximum uterine manipulation out of the pelvis and medial off of the pelvic side wall .
typically , a vaginal manipulator and 3 laparoscopic graspers are used to manipulate the uterus .
one grasper is applied to the contralateral round ligament , and 2 graspers are used as fulcrums ( figure 1 ) .
round ligaments were excised with the plasmakinetic cutting forceps ( gyrus acmi , southborough , ma ) .
retroperitoneal spaces were dissected , both ureters were identified , and the infundibulopelvic ligaments or ovarian ligaments / fallopian tubes ( depending on patient 's preference for ovarian conservation ) were excised with the pk cutting forceps . the anterior and posterior leaf of the broad ligament was dissected . using multiple laparoscopic graspers and the vaginal uterine manipulator , the uterus
after the uterus had been manipulated out of the pelvis , the bladder was dissected off the cervix with monopolar electrosurgery .
because of the enlarged size of the uterine vessels , the vessels were coagulated on the uterus prior to the standard coagulating and cutting .
all attempts were made to excise the cardinal and uterosacral ligaments with the pk cutting forceps .
the remainder of the uterosacral ligament was cut and suture ligated with 0 polyglycolic acid sutures .
pain assessment was evaluated using the visual analog scoring system : 0 - no pain , 2  mild pain , 5  moderated pain , 7  severe pain , and 10  excruciating pain . at our institution , visual analog scoring is performed and recorded every 4 hours by the nursing staff .
the highest visual analog score on postoperative day 0 or postoperative day 1 were used .
all patients were evaluated by the same nursing staff and had the same preprinted postoperative pain management protocol .
median age was 45 years old ( range , 31 to 57 ) , and median weight was 170 pounds ( range , 130 to 236 ) .
nine of the 14 patients ( 64% ) had medical comorbidities , and 6 of 14 patients ( 43% ) had prior pelvic surgery .
median operative time was 3.5 hours ( range , 2 to 4.6 ) , and median blood loss was 400cc ( range , 100 to 1200 ) .
median postoperative pain score was 4  discomforting ( range , 0 to 8) . at 28-day follow - up
interestingly , the one patient converted to laparotomy developed a pulmonary embolus on postoperative day 6 .
we were successful in performing lavh for uteri > 1000 g in 14 of 15 patients ( 93% ) .
median operating time was 3.5 hours , and median blood loss was 400 ml . all patients were discharged on postoperative day one .
consistent with a large meta - analysis showing advantages of lavh verses abdominal hysterectomy for normal size uteri , our patients had little pain , no surgical site infections , and a hospital stay of only one day .
if an abdominal approach is chosen for uteri weighing > 1000 g , a long abdominal incision would be required resulting in increased postoperative pain , increased chance of surgical site infection , and longer hospital stay .
as we have previously reported , no significant increased cost is incurred with lavh verses abdominal hysterectomy for large uteri because the increased cost of operative time associated with lavh is balanced by the increased cost of the additional 2 days of hospital stay for abdominal hysterectomy . because of the technical challenges in performing lavh for uteri > 1000 g , it is our opinion , that several surgical techniques are essential .
first , patients must be placed in a maximum trendelenburg position . because median procedure time is 3.5 hours , we recommend placing a gel pad under the buttocks to prevent the patient from gravitating towards the head of the table .
second , an adequate number of ports and surgical assistants are necessary to manipulate the uterus out of the pelvis and off of the pelvic side wall .
the round ligament , infundibulopelvic ligament ( or ovarian ligament / fallopian tubes ) and broad ligament must be resected to allow uterine manipulation .
frequently , the uterus needs to be  rocked  with the laparoscopic graspers and vaginal uterine manipulator to manipulate it out of the pelvis .
third , we do not attempt to dissect the bladder off the cervix until the uterus has been manipulated out of the pelvis to avoid bladder injury .
we performed multiple coagulations of the uterine vessels on the uterus bilaterally to control back bleeding before coagulating and cutting the uterine vessels . without performing this technique
finally , the surgeon must have patience when morcelating the uterus vaginally because it typically takes approximately one hour .
it is our opinion that vaginal morcelization with monopolar electrosurgery is approximately 50% faster than using the laparoscopic morcelator .
we performed a pub med literature search from 1965 to the present and located 6 articles addressing lavh for large uteri , but none specifically for urteri weighing 1000 g or more .
pelosi et al reported on lavh for uteri weighing 500 g. they described a single uterus that weighed > 1000 g ( 1095 g ) , but the lavh was converted to abdominal hysterectomy .
darai et al reported on lavh for uteri between 290 g and 1560 g. procedures for both of the large uteri , 1450 g and 1560 g had to be converted to laparotomy .
wang et al presented a study on lavh for uteri > 500 g , and successfully removed 2 uteri weighing more than 1000 g. lyons et al presented a study for lavh for uteri > 300 g. at least one uterus weighing > 1000 g was successfully removed .
finally , wattiez et al reported on laparoscopic hysterectomies for uteri > 500 g and successfully removed a uterus weighing 1230 g.
we successfully performed lavh for uteri > 1000 g in 14 of 15 patients ( 93% ) , with 3.5-hour operative time and 400 ml blood loss .
all patients were discharged on postoperative day 1 , and median pain was only discomforting .
we believe that lavh is a safe and effective approach for uteri > 1000 g. it is our opinion that 3 surgical techniques are required ; maximum trendelenburg position , adequate number of ports , and double coagulation of the uterine vessels .
 introduction : prospective randomized trials have proven the benefits of laparoscopic - assisted vaginal hysterectomy ( lavh ) compared with abdominal hysterectomy . the purpose of this study was to evaluate the safety and efficacy of lavh performed for uteri weighing 1000 grams.methods:fifteen patients underwent attempted lavh for uteri > 1000 g . 
 median age was 45 years old ( range , 31 to 57 ) , and median weight was 170 pounds ( range , 130 to 236 ) ; 64% had medical comorbidities , and 43% had prior pelvic surgery . 
 five ports ( 5 mm ) were used to allow maximum uterine manipulation . 
 uterine vessels were doubly coagulated.results:fourteen of 15 cases ( 93% ) were successfully completed laparoscopically . 
 median uterine weight was 1090 grams ( range , 1000 to 1650 ) . 
 median operative time was 3.5 hours ( range , 2 to 4.6 ) , and median blood loss was 400 ml ( range , 100 to 1200 ) . 
 all patients were discharged on postoperative day one , and no patients developed a postoperative complication.conclusion:we believe that lavh is a safe and effective approach for uteri larger than 1000 g. it is our opinion that 3 surgical techniques are required ; maximum trendelenburg position , adequate number of ports , and double coagulations of the uterine vessels . 
INTRODUCTION
MATERIALS AND METHODS
Technique of Laparoscopic-Assisted Vaginal Hysterectomy
RESULTS
DISCUSSION
CONCLUSION