  fluoro  refers to 
 both fluorescent and fluorinated 
 compounds . despite the shared prefix , there are very few fluorescent 
 molecules that are soluble in perfluorinated solvents . 
 
 this paucity is surprising , given that optical microscopy is a ubiquitous 
 technique throughout the physical sciences and the orthogonality of 
 fluorous materials is a commonly exploited strategy in synthetic 
 chemistry , materials science , and chemical biology . 
 we have addressed 
 this shortage by synthesizing a panel of  fluorofluorophores ,  
 
 fluorescent molecules containing high weight percent fluorine 
 with optical properties spanning the visible spectrum . 
 we demonstrate 
 the utility of these fluorofluorophores by preparing fluorescent 
 perfluorocarbon nanoemulsions . 
Supplementary Material