 in this paper , we report on a general synthetic strategy for the assembly of glycopolymers that capitalizes on the intrinsic reactivity of reducing glycans toward hydrazides to form stable cyclic n - glycosides . 
 we developed a poly(acryloyl hydrazide ) ( pah ) scaffold to which we conjugated a variety of reducing glycans ranging in structure from simple mono- and disaccharides to considerably more complex human milk and blood oligosaccharides . 
 the conjugation proceeds under mild conditions with excellent ligation efficiencies and in a stereoselective manner , providing glycopolymers with pendant glycans accommodated mostly in their cyclic -glycosidic form . utilizing a biotin - terminated pah scaffold prepared via raft polymerization 
 , we quickly assembled a panel of glycopolymers that we microarrayed on streptavidin - coated glass . 
 we then demonstrated that in these microarrays , the glycopolymer ligands bind lectins according to the structures of their pendant glycans . 
 importantly , glycopolymers containing biologically relevant branched oligosaccharides , such as sialyl lewisx , as well as sulfated glycosaminoglycan - like epitopes can be readily prepared using our methodology . 
Supplementary Material