hemorrhage from pelvic blood vessels after trauma or obstetric delivery are major health care problems . trauma is a leading cause of death worldwide and a major cause of lost quality - adjusted life years ( qalys ) .
treatment of pelvic trauma is difficult since hemorrhage can be massive and it is difficult to apply direct pressure to the bleeding vessels .
postpartum hemorrhage is the leading cause of obstetric deaths and causes an estimated 150,000 maternal deaths per year .
definitive control of severe pelvic bleeding from any cause often requires aggressive measures such as arterial embolization , laparotomy , internal fixation , or pelvic packing .
these procedures are difficult to perform because they require immediate access to sophisticated medical and surgical expertise and equipment .
blood volume must be maintained by transfusion of red blood cells , platelets , and clotting factors .
this could provide time to mobilize more sophisticated resources and might decrease transfusion requirements and the need for aggressive therapy .
pneumatic anti - shock garments ( pasg ) , also called medical or military anti - shock trousers ( mast ) , have been shown to greatly decrease pelvic blood flow [ 2 , 3 ] , and case reports imply that they are effective in patients with pelvic injuries   and postpartum hemorrhage .
however , most of the patients enrolled in clinical trials had thoracic or abdominal trauma and had ready access to definitive surgery .
they only autotransfuse about 250  cc of blood   from the lower body into the central circulation and have little or no effect on cardiac output .
these findings would explain differing outcomes for upper body versus pelvic hemorrhage . in their favor pasg
unfortunately pasg are complicated , expensive , and rarely available in the low resource areas where they would seem most useful . a simple and less expensive alternative to pasg
this non - pneumatic anti - shock garment ( nasg ) is made of neoprene and is tightly applied to the patient using velcro straps .
it has been commercialized as the zoex non - inflatable anti - shock garment ( zoex , ashland , or , usa ) .
the nasg has been shown to decrease postpartum blood loss by 50% [ 8 , 9 ] and improve survival rates from postpartum hemorrhage .
we measured pelvic blood flow in volunteers before and after being placed in the nasg and pasg .
subjects ranged in age from 21 to 60  years of age and weighed 5282  kg .
an acuson sequoia 512 ultrasound and 4vi probe operating at 23  mhz ( siemens , mountain view , ca , usa ) was used to measure heart rate , apparent artery diameter , doppler - to - vessel angle , and blood flow velocity at the abdominal aorta below the superior mesenteric artery ( sma ) .
measurements were obtained from each subject at baseline and immediately after being placed in each device .
the pasg was made by wrapping individual folded hospital sheets around each leg and the abdomen / pelvis .
after the first wrap a bicycle tube was placed on each sheet and the sheet was further wrapped around the patient and tube .
a second set of three sheets was then wrapped firmly around the first set being careful to allow the tube stem but no other part to protrude .
the tubes were then inflated with a bicycle pump to 2.83.5 bar ( 4050  psi ) .
the ultrasonographer has 20  years experience and is certified by the american registry for diagnostic medical sonography ( rockville , md , usa ) as both a registered diagnostic medical sonographer ( rdms ) and a registered vascular technician ( rvt ) .
data were analyzed with one sample and paired t tests using two - tailed p values .
mean blood flow was 1.99  l / min at baseline with a range of 0.393.05  l / min .
mean flow decrease was 1.11  l / min or 56% [ 95% confidence interval ( ci ) : 0.641.57 , p  =  0.0003 for the difference ] for the pasg and 0.65  l / min or 33% ( 95% ci : 0.031.26 , p  =  0.04 ) for the nasg .
the pasg decreased blood flow more than the nasg ( mean difference : 0.46 , 95% ci : 0.020.90 , p  =  0.04 ) .
our results are compatible with the medical literature regarding the regional hemodynamic effects of circumferential abdominal pelvic pressure using pasg [ 2 , 3 ] .
commercial pasg are quite rigid and their air bladders are considerably larger than bicycle tubes .
a previous study showed that when inflated to two thirds of their maximum , commercial pasg decrease blood flow by approximately one half , which is similar to the magnitude of decrease we demonstrated with our improvised pasg .
fully inflated commercial pasg decrease distal aortic flow by about three quarters [ 2 , 3 ] . pelvic hemorrhage and particularly postpartum hemorrhage
bleeding can be arterial from branches of the internal iliac , pelvic , ovarian , and middle sacral arteries .
bleeding will stop when externally applied pressure exceeds the perfusion pressure of the injured vessel .
low pressure venous bleeding theoretically requires only a few millibars , but this must be at the actual bleeding sites .
this is impossible to apply externally and would in addition completely eliminate tissue perfusion , causing undesirable side effects .
it provides indirect pressure on the pelvic organs that exceeds venous and capillary filling pressure .
this directly decreases arterial bleeding and hence should give normal hemostatic mechanisms more opportunity to act .
it is unfortunate that the term  anti - shock  became incorporated into the names of these devices because they have essentially no utility in reversing shock in general or in preventing it from injuries that are above the pelvis .
however , emergency care and childbirth providers need a means of slowing or stopping pelvic hemorrhage .
this is particularly true in low resource environments or when patients present late or to facilities that lack interventional radiology , immediate surgical capability , and safe blood .
delays in gaining access to definitive care are even more serious if patients suffer from preexisting anemia or have little reserve .
although we did not do any formal testing of device acceptability , we did ask all of the subjects if they wanted the trial terminated because the devices were too uncomfortable and none did .
one subject had participated in a previous pasg study and spontaneously volunteered that all three devices felt  about the same  which is reassuring given the long clinical experience with commercial pasg
hypovolemia ordinarily causes peripheral vasoconstriction which would lead to less blood flow at the distal aorta
it would be unethical and impractical to perform an initial trial on ill and bleeding subjects .
our within - subject experimental design specifically compensates for differing amounts of pelvic blood flow between subjects .
although the amount of blood flow in the distal aorta might be different , the effect of mechanical pressure and hence the comparison between devices would be the same .
although the improvised device can be made locally , the nasg is available in a manufactured version which may make it more suitable in places that can afford the initial investment .
the pasg decreased blood flow by a larger margin than the nasg , but this does not prove that it is clinically either equivalent or superior . it should be noted that the optimal pressure to treat pelvic and postpartum bleeding is not known but that the pressure in each device can be changed by adding or removing air from the tubes or adjusting the tension on the straps of the nasg .
currently available reports of nasg use in obstetric hemorrhage have not noted problems with compartment syndrome , but the number of subjects studied is small .
 backgroundpelvic bleeding from trauma and postpartum hemorrhage is often difficult to treat successfully by emergency providers particularly in low resource environments , when hospital presentation is delayed or there is a lack of immediate surgical , anesthesia , and transfusion capabilities . 
 pneumatic anti - shock garments ( pasg ) decrease pelvic blood flow and hemorrhage . 
 a tightly fitted neoprene non - pneumatic anti - shock garment ( nasg ) has been shown to decrease blood loss and improve survival rates from postpartum hemorrhage.aimsthe objective of this study was to determine whether blood flow to the pelvis is decreased by use of the nasg or by an improvised pasg.methodsa pasg was made using three bicycle tubes , placing one tube on each leg and one on the lower abdomen / pelvis , wrapping firmly with sheets and inflating the tubes to approximately 3.5 bar ( 45  psi ) . 
 a doppler ultrasound was used to measure distal aortic blood flow in 12 healthy adults at baseline and in both devices . 
 data were analyzed with one sample and paired t tests.resultsmean flow was 1.99  l / min at baseline . 
 mean flow decrease was 1.11 [ 95% confidence interval ( ci ) : 0.641.57 , p  =  0.0003 for the difference ] for the pasg and 0.65 ( 95% ci : 0.031.26 , p  =  0.04 ) for the nasg . 
 the pasg decreased blood flow more than the nasg ( mean difference : 0.46 , 95% ci : 0.020.90 , p  =  0.04).conclusionsboth devices decreased distal aortic blood flow , but the improvised pasg device decreased it by a larger margin . 
Introduction
Materials and methods
Results
Discussion