early and accurate assessment of the thoracolumbar spine is an important aspect of trauma reception and resuscitation .
between 19% and 50% of fractures may have associated neurological damage to the spinal cord.1 missed or delayed diagnosis can lead to a multitude of problems including long - term pain , reduced quality of life , and can have devastating psychological effects .
it is widely recognised that blunt trauma patients with altered mental status require imaging of the cervical and thoracolumbar spine , as clinical signs and symptoms can be unreliable.2 
 6 in patients with a glasgow coma scale ( gcs ) score of 15 , much work has been done with regard to clearing the cervical spine of significant injury with established and validated gudelines.7 
 8 to date , there are only a few small prospective studies5 
 6 
 9 
 10 and a number of small retrospective analyses directed at the assessment of the thoracolumbar spine.24 

1114 differences in clinical anatomy make direct translation of the results from studies on the cervical spine unreliable .
the greater mass , longer distance from spinous processes to anterior body and relative immobility of the thoracolumbar vertebrae compared to the cervical vertebrae are key differences . despite these differences in a recent systematic review
it has been proposed that those patients who are awake , without evidence of intoxication , with normal mental , neurological and physical examinations can be cleared clinically.15 the aim of this study was to test this hypothesis by looking at patients presenting with thoracolumbar fractures with a gcs score of 15 .
the alfred hospital is one of two adult tertiary trauma referral centres in melbourne , australia , and serves the statewide population of victoria of approximately five million .
it has an annual emergency department ( ed ) census of over 45  000 patients , with more than 1200 major trauma ( injury severity score ( iss ) > 15 ) admissions per annum .
the diagnostic imaging evaluation of the thoracolumbar spine of patients presenting to the emergency and trauma centre includes anteroposterior and lateral views of the thoracic and lumbar spine .
patients with a higher suspicion of fracture or those with pain or tenderness undergo ct scanning of the thoracic and/or lumbar spine .
patients already having ct scanning of the chest or abdomen have reformatted images of the thoracic and lumbar spine developed without additional scanning .
the ct scanner used was a ge lightspeed vct 64-slice scanner ( general electrical company , ge healthcare , milwaukee , usa ) .
the alfred trauma registry , funded as part of the victorian state trauma system , collects trauma data concurrent with the inpatient episode .
data are collected according to a defined dataset by experienced registry staff and regularly audited .
the registry collects data on all patients admitted for more than 24  h to the alfred trauma service , trauma patients with an iss of more than 15 and patients admitted for over 72  h post - injury admitted under other units .
patients with iss less than 15 and isolated trauma to the vertebrae were therefore included , provided they spent over 72  h in hospital .
all patients diagnosed with a thoracolumbar fracture presenting to the ed between january 2006 and december 2008 were identified from the alfred trauma database and included in the this study .
data collected from the trauma registry included patient demographics , mechanism of injury , the first recorded gcs score on arrival to the ed , abbreviated injury scale codes with descriptions and iss .
a subgroup of patients with an initial gcs score of 15 was identified for analysis .
a retrospective explicit chart review of these patient records was conducted by dsg and fr and audited by a third operator ( bm ) .
any records with ambiguous , missing or unknown data were reviewed by all three operators and discussed at study coordination meetings held at regular intervals .
thoracolumbar pain was coded as a symptom if mentioned in either the initial assessment notes of ambulance personnel , nursing or medical staff .
data on prehospital analgesia given and finding of tenderness on log - roll during secondary survey were gathered from chart reviews , while blood alcohol levels were obtained from the alfred pathology service .
continuous data are presented as mean with sd , whereas ordinal data are presented as medians with interquartile ranges .
student 's t test was used to calculate the significance between two continuous variables , whereas the wilcoxon rank sum test was used to compare ordinal variables .
the alfred hospital is one of two adult tertiary trauma referral centres in melbourne , australia , and serves the statewide population of victoria of approximately five million .
it has an annual emergency department ( ed ) census of over 45  000 patients , with more than 1200 major trauma ( injury severity score ( iss ) > 15 ) admissions per annum .
the diagnostic imaging evaluation of the thoracolumbar spine of patients presenting to the emergency and trauma centre includes anteroposterior and lateral views of the thoracic and lumbar spine .
patients with a higher suspicion of fracture or those with pain or tenderness undergo ct scanning of the thoracic and/or lumbar spine .
patients already having ct scanning of the chest or abdomen have reformatted images of the thoracic and lumbar spine developed without additional scanning .
the ct scanner used was a ge lightspeed vct 64-slice scanner ( general electrical company , ge healthcare , milwaukee , usa ) .
the alfred trauma registry , funded as part of the victorian state trauma system , collects trauma data concurrent with the inpatient episode .
data are collected according to a defined dataset by experienced registry staff and regularly audited .
the registry collects data on all patients admitted for more than 24  h to the alfred trauma service , trauma patients with an iss of more than 15 and patients admitted for over 72  h post - injury admitted under other units .
patients with iss less than 15 and isolated trauma to the vertebrae were therefore included , provided they spent over 72  h in hospital .
all patients diagnosed with a thoracolumbar fracture presenting to the ed between january 2006 and december 2008 were identified from the alfred trauma database and included in the this study .
data collected from the trauma registry included patient demographics , mechanism of injury , the first recorded gcs score on arrival to the ed , abbreviated injury scale codes with descriptions and iss .
a subgroup of patients with an initial gcs score of 15 was identified for analysis .
a retrospective explicit chart review of these patient records was conducted by dsg and fr and audited by a third operator ( bm ) .
any records with ambiguous , missing or unknown data were reviewed by all three operators and discussed at study coordination meetings held at regular intervals .
thoracolumbar pain was coded as a symptom if mentioned in either the initial assessment notes of ambulance personnel , nursing or medical staff .
data on prehospital analgesia given and finding of tenderness on log - roll during secondary survey were gathered from chart reviews , while blood alcohol levels were obtained from the alfred pathology service .
continuous data are presented as mean with sd , whereas ordinal data are presented as medians with interquartile ranges .
student 's t test was used to calculate the significance between two continuous variables , whereas the wilcoxon rank sum test was used to compare ordinal variables .
there were 1161 patients with thoracolumbar fractures over the study period , with a total of 1902 fractures .
the average age was 44.318.6  years with a male to female ratio of 2.8  :  1 and a median iss of 16 ( 922 ) .
gcs , glasgow coma scale score . of the 536 patients presenting to ed with a gcs score of 15 , 354 ( 66.0% ) patients received prehospital opioid analgesia .
the presence of thoracolumbar pain was documented in 325 ( 60.6% ) on initial assessment , while tenderness on log - roll was elicited in 323 ( 60.3% ) patients .
a positive blood alcohol level was defined as any value greater than 0  g per 100  ml blood .
the sensitivities of prehospital opioid analgesia , pain to thoracolumbar area , tenderness on log - roll and a positive blood alcohol , together with a combination of all variables are presented in table 1 .
sensitivity of clinical features for thoracolumbar fractures * number of patients with documentation . sensitivity ( 95% ci ) of clinical variable subgrouped by mechanism of injury mba , motorbike accident ; mva , motor vehicle accident .
all patients with a lumbar vertebral fracture complained of pain and/or received prehospital analgesia and/or had tenderness on log - roll examination .
there were 28 ( 5.2% ) patients who were diagnosed with a thoracic vertebral fracture , but received no prehospital opioid analgesia , did not complain of pain on initial presentation and had no tenderness to the thoracolumbar spine elicited on log - roll .
the median iss in this group of patients was 13.5 ( 919 ) , which was not significantly different to the iss for the overall group ( p=0.252 ) .
there were seven patients who sustained their injury after a low fall ( < 1  m ) , three patients after a high fall ( > 1  m ) , seven motor vehicle crashes , six motorcycle crashes , three bicycle related and two pedestrians .
of these 28 patients , there were 18 patients with a concurrent fracture of the cervical spine , four ( 14% ) had rib fractures and six ( 22% ) had other non - spinal fractures .
tertiary survey of these patients revealed tenderness to the thoracolumbar spine in only two cases , both of whom had concurrent cervical spine fractures .
non - significant fractures were defined as involving only one column ( stable fractures ) and not requiring operative fixation . of the above group , 25 ( 89% ) patients sustained non - significant stable fractures including 10 anterior compression fractures , eight superior end plate fractures , four transverse process fractures , one spinous process fracture and two other minor abnormalities .
the remaining three ( 11% ) patients sustained clinically significant fractures defined as those involving two or more columns ( unstable fractures according to the denis classification)16 or those requiring operative fixation .
this included a 25-year - old motorcyclist sustaining a t5 on t6 fracture dislocation , with cord compression , requiring operative fixation .
there was also a 75-year - old patient with a three column fracture from a fall from standing height and a 33-year - old pedal cyclist with a two column fracture . neither required operative fixation .
this study shows that history and examination could exclude clinically significant fractures of the lumbar vertebrae but could not exclude all fractures of the thoracic vertebrae . in major trauma patients
, we have shown that it is possible to exclude  clinically significant thoracic fractures based on history and clinical examination in a subgroup of patients .
this subgroup was defined by blunt trauma with a gcs score of 15 , the absence of documented alcohol or prehospital morphine , the absence of pain on history and tenderness on log - roll , the absence of neurology and the absence of a cervical spine fracture .
a very small proportion of patients ( 4.7% ) were found to have a thoracic fracture in the presence of the above criteria , but were limited to those with a single column injury and none required no operative management .
painless thoracic vertebral fractures have previously been described,17 and functional assessment using axial loaded movements have been proposed to determine clinical significance .
we suggest that should these patients subsequently develop pain , they should be re - examined and have imaging to exclude stable spine injury .
the most devastating clinical consequence of a missed or delayed diagnosis of a thoracolumbar vertebral fracture is the onset and progression of neurological deficits,18 
 19 due to movement at the fracture site , soft tissue swelling , or the development of an epidural haematoma secondary to prophylactic anticoagulation .
however , the risk of this occurring has not been clearly quantified in the literature .
there is also the potentially positive impact of diagnostic certainty on recovery , rehabilitation , workers compensation , and psychological wellbeing , which requires further clarification .
accurate diagnosis of all injuries remains the ultimate aim during the initial assessment of injured patients .
there is currently some evidence suggesting a mortality benefit when all major trauma patients are analysed.20 however , the use of extensive radiography is time consuming , expensive and results in unnecessary radiation exposure , with a potential long - term increased risk of radiation - induced carcinogenesis .
the benefit of whole - body ct to trauma patients based on mechanism alone , who exhibit minimal clinical symptoms and signs , remains unknown .
adopting a clinical practice of whole - body ct in this subset of patients exposes them to the long - term risks of ionising radiation and is unlikely to be associated with significant benefit .
obtaining a history and a thorough clinical examination should still play a central role in the assessment of trauma patients . in our group of patients ,
the primary difference in excluding thoracolumbar vertebral fractures compared to those of the cervical vertebrae is in the early mobilisation of patients post - history and examination .
while the cervical vertebrae may be mobilised effectively in an awake supine patient , axial loading of thoracolumbar vertebrae through mobilisation is the most effective clinical manoeuvre to detect any pain from a stable fracture .
second , the presence of a cervical spine fracture has previously been shown to be associated with another spinal fracture,21 and this was confirmed in this study , necessitating imaging of the rest of the spine .
the presence of any neurological deficit without pain is a further obvious variable , which necessitates imaging of the thoracolumbar vertebrae .
contrary to our findings , a negative physical examination alone has previously been reported to be reliable at excluding injury .
samuels and kerstein12 retrospectively reviewed 99 charts , in which 15 patients had thoracolumbar fractures .
of the 55 charts in which patients had no pain or tenderness ; there were no missed fractures .
however , that series did not report how severely injured patients were and disregarded other factors , which may influence the decision to image the thoracolumbar spine .
the findings of our study are similar to others recommending routine imaging of the thoracolumbar spine .
frankel et al9 found that 40% of 65 patients with fractures had pain or tenderness .
these patients had associated injuries and high blood ethanol levels , making it hard to determine the exact reason for the absence of clinical features .
cooper et al2 reported a review of 183 fractures in 110 patients who were neurologically intact and had a gcs score of 1315 . about a third of these patients had no pain or tenderness , yet all had fractures .
the absence of clinical findings was significantly related to the presence of another major injury , defined as abbreviated injury scale scores of 3 or more .
comparison with the findings of our study is difficult , due the small number of patients reviewed and the inclusion of patients with gcs scores of less than 15 in these studies . to date
inclusion criteria to the trauma registry excluded those patients who were discharged within 24  h and those less severely injured .
patients with clinically significant thoracolumbar spine fracture are unlikely to be included in the discharged group . with regard to missing data , very few patients did not have findings of pain on log - roll documented . using clinical assessment to determine imaging
will  miss some thoracic vertebral fractures , but the clinical significance of these fractures is likely to be minimal . the ideal technique of assessing the thoracolumbar spine on  log - roll remains unclear.15 being a retrospective review in a large trauma centre , there was a high likelihood of variation in technique for examination ranging from gentle palpation to percussion .
this would clearly impact on the presence or absence of tenderness on log - roll .
however , it has previously been noted that the  log - roll procedure is a team effort and it would be obvious to team members if pain or tenderness were present.15 furthermore , only two patients had tenderness elicited on tertiary survey following a non - tender initial examination , suggesting a measure of agreement .
the spectrum of patients presenting to a large trauma centre is likely to be different to a community hospital . although laboratory alcohol levels would not be available immediately , intoxication could be assessed initially based on clinical suspicion or breath alcohol levels .
blood alcohol level is a routine test performed on all patients who meet trauma call - out criteria .
we can safely conclude that in patients in whom blood alcohol was not measured or was negative ; a gcs score of 15 with history and clinical examination could exclude a clinically significant thoracolumbar spine fracture .
if alcohol or non - alcohol intoxicant variables were available for all patients , it would further improve the sensitivity of the rule .
the effect of a  distracting injury on the assessment of the thoracolumbar spine can not be determined from this retrospective review .
terregino et al 
 6 looked at 183 clinically evaluable patients , of whom 17 had thoracolumbar fractures , whose only symptoms predictive of a fracture were pain and tenderness .
it is possible to exclude a clinically significant lumbar vertebral fracture post - history and examination in a defined group of major trauma patients , but not a thoracic vertebral fracture .
a  clinically significant thoracic fracture may be excluded in patients with a gcs score of 15 , not under the documented influence of alcohol or prehospital morphine , the absence of pain or tenderness on log - roll , the absence of neurology , and the absence of a concurrent cervical vertebral fracture .
prospective studies are needed to develop algorithms for evaluating the thoracolumbar vertebrae in blunt trauma , based on the needs and aims of individual trauma systems .
 introductionthe aim of this study was to test the hypothesis that all blunt trauma patients , presenting with a glasgow coma scale ( gcs ) score of 15 , without intoxication or neurological deficit , and no pain or tenderness on log - roll can have any thoracolumbar fracture excluded without imaging.materials and methodsall patients diagnosed with a thoracolumbar fracture presenting to the emergency department of a major trauma centre and having an initial gcs score of 15 were included in the study . 
 variables collected included type of fracture , mechanism of injury , the presence of pain or tenderness on log - roll , ethanol levels and prehospital opioid analgesia.resultsthere were 536 patients with thoracolumbar fractures , of which 508 ( 94.8% ) patients had either pain , tenderness or had received prehospital opioid analgesia . 
 a small subgroup of 28 ( 5.2% ) patients who received no prehospital opioid analgesia , did not complain of pain and had no tenderness to the thoracolumbar spine elicited on log - roll . 
 this subgroup was significantly older ( p=0.033 ) and a high proportion of patients ( 64.3% ) had a concurrent fracture of the cervical spine . within this subgroup , a clinically significant unstable thoracic fracture was present in three patients , with all three patients exhibiting symptoms and signs of neurological injury or having a concurrent cervical vertebral fracture.conclusionsin this population of blunt trauma patients with a gcs score of 15 , not under the influence of alcohol or prehospital morphine administration , the absence of pain or tenderness on log - roll can exclude a clinically significant lumbar vertebral fracture , but does not exclude a thoracic fracture . 
Introduction
Methods
Setting
Patients
Study design
Analysis
Results
Discussion
Conclusion