congenital lip pits are malformations that occur on the paramedial portion of the vermilion border of the lip .
if it occurs along with cleft lip and palate , it is termed as vander woude 's syndrome .
the other anomalies which may or may not be associated with syndrome are hypodontia , hypoplasia , ankyloglossia , high arched palate , limb anomalies , congenital heart defects , etc .
most cases have been associated with a deletion of chromosome 1q32-q41 , but an extra chromosomal locus at 1p34 has been identified .
lip pits may result due to notching of the lip at an early stage of development with fixation of the tissues at the base of the notch or it may result from a failure of complete union of embryonic lateral sulci of the lip .
the surface opening of the lip may present as a circular or transverse slit or be located at the apex of nipple - like elevations .
its diameter may be upto 3 mm and its depth can range from 1 to 15 mm .
the problem associated with lip pits is exudation of mucous on the lower labial skin which is a source of embarrassment for the patient .
other than the lip pits , the other intraoral features should also be properly looked for and treated simultaneously .
the cleft lip and palate patients have various dental anomalies like hypoplastic , malformed , supernumerary , congenitally missing , and peg - shaped teeth .
it is also important to identify and treat these anomalies at an early stage thus improving the esthetics and function of the patient .
a 7-year - old male child reported to the department of pedodontics and preventive dentistry with a chief complaint of carious teeth .
natal history revealed that he was delivered through a caesarean section . maternal history relieved no medications or illness during pregnancy .
, it was seen that the patient was a treated case of unilateral cleft lip and palate , and two lip pits were present on the lower lip [ figures 1 and 2 ] . when the lip was compressed there was mucous secretion .
intraoral examination revealed carious teeth with 16 , 26 , 36 , and 46 and root stumps with 55 , 64 , and 65 [ figure 3 ] .
extraoral examination of the patient lip pits present on the lower lip intraoral examination of the patient ( preoperative ) : maxillary arch intraoral examination of the patient : anterior bite radiographic examination of the patient : opg the treatment planned was restoration of carious teeth followed by extraction of root stumps [ figure 6 ] .
the patient was also advised to undergo orthodontic treatment and a cosmetic lip correction for the lip pits .
it is important to diagnose these syndromes from oro facial digital syndrome and popliteal syndrome which manifests similar clinical features .
these entities are allelic variants of the same condition . the other features which help to differentiate are as follows : orofacial digital syndrome shows cleft lobular tongue , digital malformation and mental retardation , whereas popliteal syndrome shows syndactly , digital reduction , and syngathia . because the symptoms of these children are limited and because the affected individuals have normal intelligence , this disorder should not be confused with non - syndromic cleft lip and palate .
the treatment of such cases should be surgical excision of the labial and commissural pits if esthetics is a major concern .
it should include total removal of the minor salivary glands that exude secretions at the base of pits to prevent formations of cysts and mucoceles .
the treatment should be carried out in collaboration with plastic surgery , oral maxillofacial surgeons , and orthodontists .
other treatments like cross bite corrections , maxillary expansions , restorations , and extractions should also be carried out .
a multidisciplinary approach is very necessary to carry out the treatment thus improving the self - esteem of the patient at an early age .
an early and proper diagnosis followed by a multidisciplinary approach is necessary to improve the self - esteem of the patient .
 one of the most common developmental defects seen in south india is cleft lip and palate . among them 
 a few are associated with lip pits and termed as vander woude 's syndrome . 
 the early diagnosis of this rare syndrome is very necessary followed by a multidisciplinary approach . 
 it is also necessary to differentiate this syndrome from the other syndromes which may present similar features . a case report of the same is presented here requiring a multidisciplinary approach for a functional and esthetically pleasing outcome . 
Introduction
Case Report
Discussion
Conclusion