The family of Roger, Anita, and the dalmatians plan to move to Dalmatian Plantation, a home in the country with plenty of room for the 101 pups and far from the clutches of Cruella de Vil, located at Cherry Tree Farm, Little Devon. One of the dalmatians, Patch, feels lost in a sea of spots and wants to be a one-of-a-kind wonder dog like his TV hero, Thunderbolt. While watching the Thunderbolt Adventure Hour, Patch hears about a chance to appear on the show while it's filming in London. However, the family move will cause a problem for Patch's opportunity. However, he is accidentally left behind in the commotion. Patch heads for the audition to meet his hero and find out if he one of a kind, or just one of 101.