Hagerstown is a center of transit and commerce. Interstates 81 and 70, CSX, Norfolk Southern, and the Winchester and Western railroads, and Hagerstown Regional Airport cross in the city. Hagerstown is also the chief commercial and industrial hub for a greater Tri-State Area that includes much of Western Maryland as well as great extents of South Central Pennsylvania and the Eastern Panhandle of West Virginia. Hagerstown has often been referred to as and is nicknamed the "Hub City".