The setting for the game begins in Pic des Pyréneés, France, on 2005. Although the story moves five years forward to Las Vegas, United States of America on July 2, 2010, the same day of Logan Keller's arrival to Las Vegas in "Rainbow Six: Vegas". Terrorists have gained control of Las Vegas to install widespread panic in both the public as well as law enforcement agencies, such as the National Security Agency, North Atlantic Treaty Organization, Rainbow, as well as local SWAT. As the plot unfolds, however, the setting moves away from Las Vegas to other places, such as a small town in Nevada, unlike in the first Rainbow Six: Vegas, which was mainly in Las Vegas.