The book has been criticized for endorsing paranormal claims and pseudoscience. In a review, clinical neurologist Sebastian Dieguez said the book is "painstakingly redundant, astoundingly arrogant in its claims and intents". Dieguez wrote that the authors of "Irreducible Mind" took reports of paranormal phenomena and wild claims at face value, talked "quantum babble" and formed an ignorant "soul of the gaps" argument.