Aescwine was the son of Cenfus, who also ruled Wessex as a subking. They both claimed descent from Cynric through his son Ceolwulf. After the death of Cenwalh the underkings took over Wessex and ruled it for about ten years. According to the Anglo-Saxon Chronicle Cenwalh was succeeded as ruler by his wife Seaxburh. She ruled for about one year trying to hold central control over Wessex. In 675, Aescwine defeated Wulfhere over territory north of the Thames. Aescwine reigned from about 674 to 676. He was succeeded by Centwine.