During his conquests of Asian regions, Alexander collected plant and animal specimens for Aristotle’s research. Aristotle developed the first zoo and botanical garden in existence. Alexander may also have given money to the Lyceum. In 322 BC, Aristotle was forced to flee Athens with his family when the political leaders reacted against the Macedonians. Aristotle's published works supporting Macedonian rule left him a target. He passed on his Lyceum to Theophrastus and died later that year near his hometown.