Makoto Naegi and 15 other smart students (in a certain area) enter a beautiful high school named Hope's Peak Academy. In the game, Makoto Naegi enters the school building before fainting and waking up in a classroom. While in the animation, Makoto steps foot onto the school and immediately falls unconscious. He then goes to the gym to meet fifteen other high school students who joined Hope's Peak Academy. After the introductions, a robotic bear named Monokuma introduces himself and states that they are trapped in the school. The only way to escape is to commit murder without getting caught by the other students. For the rest of the game/animation, Makoto and his classmates are to find the murderer's of each case, if they do not find the murderer they will be executed, if they do find the murderer, only the murderer will be executed.