At its peak, the Hittite Empire covered most of modern Turkey and Syria. This was under the reigns of Suppiluliuma I (~1350–1322) and Mursili II (~1321–1295 BC). They had up-and-down relationships with Ancient Egypt to the south, and the Assyrian Empire in Mesopotamia. They were a party to the first known peace treaty, which was made with Ramesses II of Egypt by Hattusili III in 1258 BC.