The predators of the least weasel include red foxes, sables, steppe and forest polecat, stoats, eagle owls and buzzards. Owls are very good at catching least weasels. Some of the owls that hunt least weasels include barn owls, barred owls, and great horned owls. Other birds of prey that eat the least weasel include broad-winged buzzards and rough-legged buzzards. Some types of snake may eat the least weasel. They include the black rat snake and the copperhead.