Goblet cell and submucosal gland hyperplasia: Among the physical changes that may happen in airway remodeling is "goblet cell hyperplasia" and "submucosla gland hyperplasia". Submucosal glands and goblet cells make mucous which helps to protect the airways by trapping harmful particles like dust and pollen. The mucous is normally a thin film which lines the airways. The mucous and whatever particles they trap are brought up to the "pharynx" by tiny (microscopic) hairs on the inside of the airway that move back and forth called "cilia".