Clarke is known for playing Tommy Caffee on the television series "Brotherhood". He has also appeared in many movies such as "Death Race" (2008), "Public Enemies" (2009), "Zero Dark Thirty" (2013), "White House Down" (2013), "Dawn of the Planet of the Apes" (2014), "Terminator Genisys" (2015), "Everest" (2015) and "Chappaquiddick" (2017).