Wistert played for the Michigan Wolverines before his two brothers, Al Wistert and Alvin Wistert, did. All three Wistert brothers wore the number 11 for the Wolverines football team, and all three were members of the College Football All-America team, which is the best players through all of the United States. When interviewed by the "Detroit News" in 2004, brother Alvin Wistert said, "And if I'm not mistaken I think this is unprecedented in the of college football: that three brothers all would go to the same school, all played football. All played tackle, all wore the same number 11, all made All-American. Two of us played on four national championship teams. They all made it into the College Football Hall of Fame." 