At No Way Out, The Big Show made a surprise return to the company. In his return promo, Big Show threatened to give Rey Mysterio a Chokeslam. Professional boxer Floyd Mayweather, Jr., who was in attendance and a close friend of Mysterio's, came to his aid and confronted Big Show. Big Show then got on his knees to allow Mayweather to punch him, which Mayweather did, by hitting him with many different punches, which caused Big Show to bleed from the nose and mouth. The next night on "Raw", the Big Show challenged Mayweather to a match, which Mayweather accepted.