Tenenbaum is author or coauthor of about 200 scientific publications. Most of them are original research articles published in critically peer-reviewed renowned medical journals. His research included several areas, including echocardiography, cardiac CT, heart failure, cardiac calcification and cardiac rehabilitation. Tenenbaum was especially involved in the research of various aspects of "metabolic syndrome", insulin resistance, obesity and the diabetes/cardiovascular interrelationship including residual risk concept.