The World Hepatitis Alliance coordinates World Hepatitis Day, held every year on July 28. The economic costs of hepatitis C are significant both to the individual and to society. In the United States the average lifetime cost of the disease was estimated at 33,407 USD in 2003, with the cost of a liver transplant approximately 200,000 USD as of 2011. In Canada the cost of a course of antiviral treatment was as high as 30,000 CAD in 2003, while the United States costs are between 9,200 and 17,600 in 1998 USD. In many areas of the world people are unable to afford treatment with antivirals because they lack insurance coverage or the insurance they have will not pay for antivirals.