The 2010 Census says that Labette County had 21,607 people living there. The median age was 41. The race of the people were 85.5% non-Hispanic white, 4.7% African-American, 2.2% Native America, 0.4% Asian, 0.1% non-Hispanics of some other race, 3.6% non-Hispanics reporting two or more races and 4.0% Hispanic or Latino.