Radhakrishnan's eldest son M. R. R. Vasu was a leading character artist until the mid-1980s. His other son Radha Ravi is also an actor. Radhika is an actress and producer and is presently married to actor R. Sarathkumar (her third husband). Nirosha (also known as Niroja) is an actress working mostly in supporting roles; she is married to actor Ramki.