Khanna played lead roles in many movies and is best remembered for his performance in "Mere Apne, Mera Gaon Mera Desh, Gaddaar, Jail Yatra, Imtihaan, Muqaddar Ka Sikandar, Inkaar, Kuchhe Dhaage, Amar Akbar Anthony, Rajput, Qurbani, Kudrat, Dayavan, Kaarnama," and Jurm".