In modern times, the concept of substance is treated and spread widely. The first view is connected with an ontological understanding of substance as ultimate bases being (Francis Bacon, Benedict Spinoza, Gottfried Wilhelm Leibniz). Central category of metaphysics in philosophy substance is identified as with God and with nature and determined as the cause of itself (Latin, "causa sui"). The main characteristics (attributes) of a substance from Benedict Spinoza are thinking and stretch. By analogy with the philosophy of Benedict Spinoza substance considered in the light of the concept of René Descartes and Leibniz. The first substance is a unity of subject and object, and the second - the same atoms are simple beings who lose their stretch, but receive attribute aspirations (French, "appetitio"n) and multiplicity. Thanks Leibniz substance begins to associate with matter.