She also researches risk factors such as obesity, smoking, hypertension, high blood cholesterol and lack of exercise, which affect chronic diseases. She emphasizes the importance of social determinants of health and strongly advocates for social and political changes that would promote more healthy lifestyles. She is particularly concerned about women, who are at a higher risk of developing obesity than Saudi men, in part because socio-cultural factors restrict opportunities for women to exercise and discourage women's participation in sports. Altwaijri advocates for the inclusion of a physical curriculum for girls as well as boys in schools; creation of safe neighborhood play spaces for both male and female children; safe areas where adult men and women can be physically active; and affordable health clubs for both women and men. She also supports regulation of food prices to promote the choice of healthy over unhealthy foods. To keep her children active, she enrolled them in competitive team swimming, where they became eligible to attend the AAU Junior Olympic Games.