Since 1975, he has been married to Susan Scheinberg. They met while they were both graduate students at Harvard. Scheinberg is a Ph.D. in classics. They have three children. Their daughter Anne is married to writer Matthew Continetti. Continetti is editor-in-chief of The Washington Free Beacon. Their son Joseph served in the U.S. Marine Corps in Afghanistan and worked for the management consulting company McKinsey & Company. He started working as legislative director for Senator Tom Cotton in 2018. Kristol lives in Northern Virginia.