DNA sequence analysis has shown that Ötzi had brown eyes, blood type 'O', was lactose intolerant, and was likely to suffer heart disease. He was more closely related to modern Corsicans and Sardinians than to populations in the Alps, where he was discovered. His ancestors probably came from the Middle East as agriculture became more widespread. He was also the first known case of a person infected by the Lyme disease bacterium. He was middle-aged.