Michele is active in charities for gay rights and animal rights, as well as in numerous other charities. In 2008, Michele was a part of the PETA ad campaign "Buck Cruelty! Say No to Horse-Drawn Carriage Rides". In April 2010, Michele appeared in a PSA for PETA speaking out against fur clothing. In September 2010, Michele was honored by PETA for her work for animals. In addition to working with PETA, Michele is also a vegan.