If a person has liver abnormalities (changes in the liver that are not normal) due to Hepatitis C virus infection, the person should get treatment. The first treatment that is used is a drug called pegylated interferon given together with the antiviral (virus-killing) drug ribavirin. These medications are given for 24 or 48 weeks, depending on what type of Hepatitis C virus the person has. About 50–60% of people who are treated improve. For people with Hepatitis C virus genotype 1, treatment may work even better if another medication - either boceprevir or telaprevir - is given along with ribavirin and peginterferon alfa. Side effects with treatment are common; half of people treated get flu-like symptoms, and a third have emotional problems. Treatment works better if it is given during the first six months than after Hepatitis C becomes chronic. If a person gets a new infection and it has not cleared up after eight to twelve weeks, doctors usually suggest giving pegylated interferon for another 24 weeks. For people with thalassemia (a blood disorder), ribavirin appears to be a helpful treatment, but it makes it more likely for patients to need blood transfusions (where they need to be given blood from another person).