In 2011, Mané came from Génération Foot to FC Metz in France. He played for the youth teams and the second team. His first game in the first team was on 24 January 2012 against SC Bastia. In 2012, he moved to Austria. There he played for Red Bull Salzburg in the Austrian Bundesliga. He won the Austrian Bundesliga and Austrian Cup in 2014 with Salzburg. In 2015, he moved to Premier League club Southampton.