The same disease is thought to have returned to Europe every generation with different degrees of intensity and fatality until the 1700s. Later outbreaks include the Italian Plague of 1629-1631, the Great Plague of London (1665–1666), the Great Plague of Vienna (1679), the Great Plague of Marseille in 1720–1722 and the 1771 plague in Moscow. In its virulent form it seems to have disappeared from Europe in the 18th century.