Syracuse is at (37.982938, -101.751224). It is along U.S. Route 50 and the Atchison, Topeka and Santa Fe Railway. It is sixteen miles (twenty-six kilometers) away from the Colorado border. The Arkansas River goes south of the City of Syracuse. The countryside south of the Arkansas River has sandhills. The "Syracuse Sand Dunes" is in these sandhills. It is a city park covering , including a fishing pond.