22-Shruti-Harmonium was created by Vidyadhar Oke (Indian Patent No. 250197). To achieve this, he first clarified the essential difference between 'Nada' and 'Shruti' and pinpointed the positions to play the 22 Microtones (Shrutis) on any string instrument. He documented the specific difference between 22 Shrutis versus the 12-Tone Equal temperament Scale. His 22-Shruti-Harmonium provides special knobs below each of the keys to regulate the reeds, making 22 Shrutis available within 12 keys. As this is a modified hand-pumped harmonium, no special playing skill is necessary. The 22-Shruti-Harmonium enables the creation of any Raga with all the notes perfectly consonant with a Tanpura. Additionally, by positioning all the knobs in the central position, the 22-Shruti-Harmonium can produce the sound of an Accordion.