MDMA is illegal in most countries. Possessing, making or selling it could result in criminal prosecution and a possible prison term. Some countries, such as the U.S., have made limited exceptions to these laws for research. There have been some initial studies on whether it can help patients with severe PTSD (post-traumatic stress disorder) make progress in therapy if they take very low doses of MDMA immediately before appointments (under medical supervision). , MDMA has no accepted medical uses.