Appendicitis is the inflammation of the appendix. The appendix is a pouch at the start of the large intestine. Symptoms usually include a sharp pain in the lower right abdomen. Also, nausea, vomiting, and decreased appetite are common. However, about 40% of people do not have these typical symptoms. If the appendix ruptures (splits) the result is painful peritonitis, and sepsis. Therefore immediate treatment in hospital is needed for appendicitis. Usually the infected appendix is taken out.