Scottish virologist June Almeida at St Thomas' Hospital, London, compared the structures of IBV, B814 and 229E in 1967. Using transmission electron microscopy the three viruses were shown to be similar in shape and have club-like spikes. A research group at the National Institute of Health the same year isolated another member of this group of viruses. Like B814, 229E, and IBV, the novel cold virus OC43 had distinctive club-like spikes when observed with the electron microscope.