Jiske Griffioen (born 17 April 1985 in Woerden) is a Dutch wheelchair tennis player. She was born with Spina bifida. Before she started her career as a wheelchair tennis player, she was a member of the national wheelchair basketball team at the 2000 Summer Paralympics in Sydney at the age of 14. Griffioen has won Grand Slam titles in doubles play at the Australian, French and US Opens and on four occasions has won the end of year Masters doubles.