Price raised the Second Regiment, Missouri Mounted Volunteer Cavalry and was appointed its colonel on August 12, 1846. He marched his regiment under Alexander Doniphan to Santa Fe, where he assumed command of the Territory of New Mexico after Gen. Stephen W. Kearny, departed for California. Price served as military governor of New Mexico, and put down the Taos Revolt, an uprising of Native Americans and Mexicans in January 1847.