In 1850, she joined Perrot in St. Petersburg, Russia. He had been appointed balletmaster to the Imperial Ballet. She danced "Giselle" at the Imperial Bolshoi Kamenny Theatre. The first Giselle in Russia had been danced by Fanny Elssler. The initial reaction to Grisi's interpretation of the role was not enthusiastic. Over time, the Russians came to appreciate her talents. She was "Prima Ballerina" of the St. Petersburg Imperial Theatres in St. Petersburg from 1850 to 1853. She worked with Perrot and also Joseph Mazilier. 