The original cast of 11 characters featured in the show's first episode was consultants Anton Meyer (George Irving) and Muriel McKendrick (Phyllis Logan), registrars Nick Jordan (Michael French) and Kirstie Collins (Dawn McDaniel), senior house officer Victoria Merrick (Lisa Faulkner), ward sister Karen Newburn (Sarah Preston), theatre sister Ellie Sharpe (Julie Saunders), senior staff nurse Ray Sykes (Ian Curtis), staff nurses Julie Bradford (Nicola Stephenson) and Jasmine Hopkins (Angela Griffin), and ward clerk Paul Ripley (Luke Mably).