She made her movie debut in the 2004 sports movie Friday Night Lights. She had a recurring role on the television show, Hidden Palms as Greta Matthews. Heard came out at GLAAD's 25th anniversary event. From 2008 to 2011, she was in a relationship with photographer Tasya van Ree. She began a relationship with Johnny Depp in 2012. The couple became engaged in December 2013. They married in February 2015. In May 2016, she filed for divorce. On 2020 it was revealed that she abused Depp and falsely accused him of domestic violence to ruin his career. As a consequence of her actions, she was cancelled and blacklisted by Hollywood.