"Mother Tucker" was written by Tom Devanney. James Purdum is the director of the episode. The radio station Brian worked for (called "Weenie and the Butt") uses many sound effects. The sound effects were made by people who sung at the Academy Awards. Seth MacFarlane (creator of "Family Guy") said that it took longer than normal to make the sound effects because they did not sound serious enough. Phyllis Diller guest stars as Peter's mother Thelma. Tamera Mowry and Gore Vidal are also guest stars in the episode. A part of the episode has Thelma trying to tell Peter that she is dating Tom Tucker. She says "Tom here has won a local Emmy for his work with the retardeds". The Fox network does not want the word "retard" or "retarded" to be broadcast on the network. However, this part of the episode was shown anyway. MacFarlane said he does not understand why Fox does not let them use the word retard, but other networks do. He said that this part of the episode made the mental health community angry. 