The following year, Knight began a 28-mural series for Chicago’s Field Museum of Natural History, a project which showed the history of life on earth and took four years to complete. At the Field Museum, he produced one of his best-known pieces, a mural featuring "Tyrannosaurus" and "Triceratops". This confrontation scene between a predator and its prey would inspire many imitations, establishing the two dinosaurs as 'mortal enemies' in the popular consciousness.