Benzodiazepines affect the central nervous system, increasing the effects of the inhibitory neurotransmitter known as GABA. This results in a person experiencing a sensation of calmness and sedation, resulting in feeling more relaxed, less anxious, and increased drowsiness. When people use benzodiazepines, even under a doctor’s care, they can develop a tolerance, which means that they will require increasingly larger doses to achieve the desired effects. With escalating use and at higher doses, a person may find that they require the drug to feel and function normally. This indicates the development of dependence which, once established, may result in a person experiencing symptoms of withdrawal.