Enrique was born in Valencia. He started career with Levante before signing for rivals Valencia. He also made La Liga appearances for Celta and Villarreal. He then spent nine years in England with Newcastle United and Liverpool, totalling 161 Premier League appearances. With Liverpool, He won the League Cup and lost the FA Cup final in 2012. He retired because of injury in 2017, after a year back in Spain with Real Zaragoza.