Louis Pasteur and Robert Koch are the founders of medical microbiology. Louis Pasteur is famous for his experiments when he disproved the theory of spontaneous generation. He offered method for food preservation (pasteurization) and vaccines against anthrax, fowl cholera and rabies. Robert Koch contributed to the germ theory of disease, provided that specific diseases were caused by specific microbes. He developed criteria known as the Koch's postulates and was among first to isolate bacteria in pure culture resulting in his description of several bacteria including "Mycobacterium tuberculosis", the causative agent of tuberculosis.