Giancarlo Ghironzi (25 February 1932 – 14 March 2020) was a Sammarinese politician. He was twice Captain Regent of San Marino from 1 April 1961 to 1 October 1961, and from 1 October 1969 to 1 April 1970. He was a member of the Sammarinese Christian Democratic Party (PDCS).