Also, once a toxin gets into the bloodstream, the body immediately starts trying to get rid of it through excretion. The main organs involved with excretion are the kidneys, liver, and lungs. If a person has damage to any of these organs (like kidney failure or cirrhosis of the liver), they will be unable to get rid of the toxin as fast as a healthy person will. The chemical will stay in their body longer, and have more toxic effects.