Spencer started her career by going to numerous film schools and participating in theatre productions. She has featured in many commercials and modelling shoots. In 2018, she was cast for a role in the Nickelodeon series "Cousins for Life" as Ivy. In 2019 it was announced that Spencer had landed the role of Izzy in Netflix series "BlackAF" alongside Kenya Barris, Rashida Jones, Iman Benson and others. "BlackAF" was released in 2020. She was also featured in the Netflix film "Bright" as Sofia Ward alongside Will Smith, Joel Edgerton and Noomi Rapace among others.