She married Victor Amadeus of Savoy, on 10 February 1619 at the Louvre in Paris. Her husband was styled the Prince of Piedmont and as such she the Princess. Victor Amadeus was the eldest surviving son of Charles Emmanuel I, Duke of Savoy and Catherine Michelle of Austria the latter of which had died in 1597 as a result of childbirth. As such, Christine was the most senior female at the Savoyard court from the time of her arrival. Her husband was nineteen years older than she. Despite the age gap, the couple were happy and overall produced eight children, four of whom would survive childhood. 