Some STIs can also be spread in ways other than having sex. For example, herpes simplex and hepatitis B could be caught by a virgin without having sex, but can also be caught through sex. Some types of STIs can spread from contact between the genitals, mouth, anus, skin, eyes, and (rarely) infected surfaces; this depends a lot on the type of STI and how it spreads. Some common diseases like HPV can cause warts and cancer in the genitals or anus or throat.