Hwang joined Wyle Laboratories in September 2001. At first she worked as a scientist in the sensors group. This work included research for monitoring the health of cell cultures on the space shuttle or station. In 2002 she moved to the neurosciences group. This group studies the effects of space flight on astronauts, with a focus on helping them adapt to space and their return to Earth. In 2011, Hwang moved to the Integrated Science & Engineering (ISE) group.