The draw for the Round of 16, which was conducted by UEFA General Secretary David Taylor, was also held on Friday, 21 December 2007 at 13:00 CET in Nyon, Switzerland. The first legs were played on 6 March 2008. The second legs were played on 12 and 13 March 2008. Unlike the previous rounds, teams from the same group or country may be drawn together from the round of 16 onwards.