There have been over 51 cases of NPS. Rarely is the case of adulthood and teenage age, the average life expectancy of NPS is 7 months. The illness syndrome was first described in 1979 as a sickness syndrome by Hans-Rudolf Wiedemann, who previously described two cases of the disease: one in 1966 and another in 1977. Thomas Rautenstrauch in 1977 recognized the syndrome of two siblings as Progeria.