Arthur E. Chase (February 4, 1930 – January 5, 2015) was an American businessman and politician. He represented the Worcester District in the Massachusetts Senate from 1991–1995. He co-founded the Central Massachusetts Legislative Caucus. In 1991 he designed the Massachusetts Academy of Math and Science at WPI and in 1992 sponsored legislation to create it. He was the Republican nominee for Secretary of the Commonwealth of Massachusetts in 1994, but lost in the general election to William F. Galvin.