The series is about two brothers, Lincoln Burrows (Dominic Purcell) and Michael Scofield (Wentworth Miller). Burrows has been sentenced to death for a crime he did not commit, and Scofield creates a detailed plan to help his brother escape prison and clear his name. Robin Tunney, Robert Knepper, Amaury Nolasco, Sarah Wayne Callies, Peter Stormare, Marshall Allman, Wade Williams, Paul Adelstein and Rockmond Dunbar also star, along with many others.