In 1662 John Graunt analysed the mortality rolls in London before the Great Plague. This gave statistical evidence for and against various theories of disease. Dr. John Snow investigated the causes of the 19th Century Cholera epidemics. He noticed the significantly higher death rates in two areas supplied by Southwark Water Company. He showed the Broad Street pump was the origin of the Soho epidemic, a classic example of epidemiology He used chlorine in an attempt to clean the water and had the pump handle removed. This stopped the outbreak. It was a major event in the history of public health, and the founding event of the science of epidemiology.