Mirza reached the quarter-finals at Hobart as No. 6 seed. She lost to Flavia Pennetta in three sets. She reached the third round at the Australian Open as No.31 seed, where she lost to No.8 seed Venus Williams 7-6(0) 6-4, having led 5-3 in the first set. She was runner-up in the Australian Open mixed doubles partnering Mahesh Bhupathi. Sun Tiantian and Nenad Zimonjić won the final 7–6(4), 6–4.