Neutrophil granules contain a variety of toxic substances that kill or inhibit growth of bacteria and fungi. The main products of the neutrophil are strong oxidizing agents. These include hydrogen peroxide, free oxygen radicals and hypochlorite. Neutrophils are the most abundant type of phagocyte, with 50 to 60% of the total circulating leukocytes. They are usually the first cells to arrive at the site of an infection. The bone marrow of a normal healthy adult produces more than 100 billion neutrophils per day, and more than 10 times that many per day during acute inflammation.