The Rhine is an important waterway. can be used by ships, and boats can go to the Black Sea using the Rhine-Main-Danube Canal. Many goods are transported over the Rhine, and the Rhine valley is also an important wine producing region. The river Rhine begins at "Tomasee", a lake in the canton of Graubünden in Switzerland, and runs through Switzerland, Germany and the Netherlands. It is the border between Switzerland and Liechtenstein and also the border between Germany and France. It is also the border between Switzerland and Austria. It is also the border between the Netherlands and Germany. It is the border between France and Switzerland. It runs through Basel, Bonn, Cologne and Duisburg. It also separates the cities of Mainz and Wiesbaden. The Rhine has 50 species of fish. The Rhine is one of the longest and most important river in Europe.