Hepatitis C is usually spread by blood-to-blood contact (when blood from a person with Hepatitis C contacts (touches or gets into) another person's bloodstream). The most common ways that this happens are through intravenous drug use (when a person shoots drugs into one of their veins, with a needle that was already used by a person infected with Hepatitis C); nonsterile medical equipment (medical tools that were not cleaned well enough after being used on an infected person); and blood transfusions (when a person is given blood that came from an infected person).