Bounty hunters Marquis Warren and John Ruth agree to travel together. Ruth has a prisoner, Daisy Domergue, who will die when he turns her in. Along the way, they agree to let former Confederate Chris Mannix travel with them, but they do not believe his story that he is the new sheriff. During a blizzard, they stop at an inn. There, they find several more people, including Confederate General Sandy Smithers, cowboy Joe Gage, and executioner Oswaldo Mobray. Bob, a worker, says the inn's owner is traveling. Warren and Ruth do not trust anyone and take all their guns. Warren, who fought for the Union Army, kills Smithers after saying that he also killed Smithers' son. Gage secretly poisons Ruth and his friend, O.B. Jackson. As Ruth dies, Domergue shoots and kills him with his own gun. Bob, Gage, and Mobray admit that they are part of Domergue's gang. Warren and Mannix agree to help each other, and they kill everyone but Domergue. Jody, Domergue's brother, comes out of hiding and seriously injures Warren. After Jody dies, Domergue says she will let Mannix go if he kills Warren. Mannix considers her offer but rejects it. Mannix and Warren kill her but they both die from blood loss.