Lake Okeechobee is the largest lake in the U.S. state of Florida. Lake Okeechobee covers about 730 square miles (about half the size of Rhode Island). The lake is shared by Glades, Okeechobee, Martin, Palm Beach, and Hendry counties. Some cities on the shore of Lake Okeechobee include: Belle Glade, Clewiston, Okeechobee, and Pahokee. 