Wiggins played college basketball at the University of Kansas. During his first year there, Wiggins was able to average 17.1 points per game (ppg), 5.9 rebounds per game (rpg), and made 34.1% of his three-pointers. On January 13, 2014, in a game against Iowa State, Wiggins scored 17 points and gained 19 rebounds in a 77–70 victory. He became only the second freshman in the last 15 years (along with Michael Kidd-Gilchrist) to earn those numbers in a win against a ranked opponent.