Stressed animals would choose to avoid a novel situation rather than confront it. Aggressive behaviour is associated with sex hormones, such as testosterone, and specific brain regions and systems such as the medial preoptic nucleus, prefrontal cortex-dependent response inhibition, and anterior hypothalamus. Stress negatively impacts sex hormones, which results in an imbalance and reduction in aggression related hormones and function. Also, chronic stress results in prefrontal cortex-dependent response inhibition. This results in reduction in aggression, thus promoting anti-predator responses.