Ohno was born in Zama on January 23, 1984. She played for Nippon TV Beleza from 1999 to 2010. In 12 seasons, she played 192 matches and scored 136 goals. She became top scorer 3 times (2007, 2008 and 2010) and she was selected MVP awards 3 times (2005, 2007 and 2010). She was also selected Best Eleven 8 times (2001, 2002, 2005, 2006, 2007, 2008, 2009 and 2010). The club won Nadeshiko League championship 8 times and 2nd position 4 times. In 2011, she moved to INAC Kobe Leonessa. In 2011 season, she became top scorer with teammate Nahomi Kawasumi. From 2013, she played for Olympique Lyonnais (2013), AS Elfen Sayama FC (2013), Arsenal WFC (2014), INAC Kobe Leonessa (2015-2017) and Nojima Stella Kanagawa Sagamihara (2018-2019). She retired end of 2019 season.