After beginning her career on stage, Anderson achieved international recognition for her role as FBI Special Agent Dana Scully on the American sci-fi drama series "The X-Files" for all ten seasons (1993–2002, 2016). Her film work includes the dramas "The Mighty Celt" (2005), "The Last King of Scotland" (2006), "Shadow Dancer" (2012) and two "X-Files" films: "The X-Files: Fight the Future" (1998) and "The X-Files: I Want to Believe" (2008). Her other notable television credits include: portraying Lady Dedlock in the successful BBC production of Charles Dickens' "Bleak House", Wallis Simpson in "Any Human Heart", portraying Miss Havisham in "Great Expectations" (2011) and Dr. Bedelia Du Maurier on "Hannibal". In 2013, Anderson began starring as DSI Stella Gibson on the critically acclaimed BBC crime drama television series "The Fall". She has been serving as an executive producer from its second series. She will be appearing as goddess Media in the upcoming TV series "American Gods". Anderson is the co-writer of "The EarthEnd Saga" novel trilogy and the self-help guide book "WE: A Manifesto for Women Everywhere".