Alfano was also Minister of the Interior from 28 April 2013 to 12 December 2016, serving in the governments of Matteo Renzi and Enrico Letta; from 2013 to 2014. He held the office of Deputy Prime Minister of Italy, as part of the Letta Cabinet, and previously served as Minister of Justice from 2008 to 2011 as part of the Silvio Berlusconi Cabinet. He was the first and only secretary of the centre-right party The People of Freedom (PdL) from 2011 to 2013.