Christened Luisa Maria Teresa Anna, but known as María Luisa was born at the Ducal Palace of Colorno in the Duchy of Parma. She was the favourite child of her mother, who tried to engage her to the heir to the French throne, however the prince died in 1761. In 1762 Maria Luisa became engaged to the Prince of Asturias (heir to the throne), Charles, later King Charles IV of Spain. She married the future Charles IV on 4 September 1765. From her marriage she was the most senior female at the Spanish court, Queen Maria Amalia having died in 1761. 