Guápulo is a district of Quito, Ecuador, also called an electoral parish ("parroquia electoral urbana"). The parish was established as a result of the October 2004 political elections when the city was divided into 19 urban electoral parishes. Set behind Hotel Quito, the neighborhood of Guápulo runs down the winding Camino de Orellana, from González Suárez to Calle de los Conquistadores, the main road out of Quito and to the neighboring suburbs.