Barnell was married four times. Her first marriage was to a German musician who played in the band for John Robinson's Circus. She had two children with him. Her husband and their two children died within several years. Her second husband was a balloonist who was killed months after their marriage. Her third marriage was to an alcoholic whom she divorced. Her last marriage, in 1931, was to her manager Thomas O'Boyle, an orphan ex-circus clown and a sideshow talker for Hubert's Dime Museum. She had little contact with her family after she became a performer. She believed they thought she was a disgrace. By 1940, she claimed to have not seen her siblings in 22 years and believed them to be dead. One of her sisters worked as a nurse helping blind Chinese children.