The podcast features discussions having to do with their lives as professional creators for YouTube, the content of their most recent videos as well as their interests and annoyances. Typical topics include how to behave on the internet, movie and TV show reviews, plane accidents, flags, future studies, Apple devices, and the differences between Grey's and Haran's personalities and lifestyles. Listeners can talk about the podcast in CGP Grey's subreddit, the Hello Internet subreddit, or Twitter, where the hosts are often active. Usually, each episode usually starts with feedback from listeners. The podcast has an official flag called the "Nail & Gear" which was decided by postal referendum.