François de Bourbon (or Francis of Bourbon), Duke of Châtellerault (1492 – 13 September 1515) was a French prince from the House of Bourbon-Montpensier, a cadet branch of the House of Bourbon (itself a cadet branch of the Capetian dynasty). He was the brother of Louis II, Count of Montpensier, Charles III, Duke of Bourbon (also known as "The Constable of Bourbon"), Louise de Bourbon, Duchess of Montpensier, and Renée of Bourbon (who became Duchess of Lorraine on 26 June 1515, less than three months before François's death).