He would create "Dexter's Laboratory" at Cartoon Network. He worked alongside Craig McCracken to help him with "The Powerpuff Girls". The success of both cartoons helped Genndy create "Samurai Jack" for the same broadcasting company. George Lucas contacted Genndy to make a "Star Wars" cartoon while doing "Samurai Jack". Genndy shifted work between Adult Swim and Sony Pictures Animation. He directed the first three "Hotel Transylvania" movies and made a fifth season of "Samurai Jack" on Adult Swim. He would later create Primal, a prehistoric animated show with no spoken speech.