The game begins in 1958, two years before the events of "BioShock." At this time, Rapture has not yet fallen into disorder. Subject Delta is responsible for protecting one specific Little Sister (little girls whose job is to collect ADAM, a liquid that gives people powers) named Eleanor. Eleanor is attacked by Splicers (humans that are addicted to ADAM), but Subject Delta kills the Splicers and tries to rescue Eleanor. However, it turned out that her mother, Sofia Lamb, hired the Splicers to take back Eleanor. She then hypnotizes Subject Delta to kill himself.