Mathilde Krim (; née Galland; July 9, 1926 – January 15, 2018) was an Italian-American medical researcher. She was the founding chairman of amfAR, the American Foundation for AIDS Research. She was born in Como, Italy to a Swiss Protestant father and Italian Roman Catholic mother. She worked at Weizmann Institute of Science, Cornell University Medical School, and at Sloan-Kettering Institute for Cancer Research. 