The show opens with the suicide of Mary Alice Young, a housewife who lives on Wisteria Lane. After that, Mary Alice narrates about her 4 friends: Susan Mayer - a divorced mother who falls in love with her new neighbor Mike Delfino; Bree Van de Kamp - seemingly "the perfect housewife and the perfect mother"; Gabrielle Solis - a former model who married a rich husband, but she has an affair with her teenager gardener; and Lynette Scavo - who has 4 kids and her husband at his work all the time. While they try to be the best mothers and housewives, they try to understand why Mary Alice killed herself, and they find a mysterious letter and a cassette with a recording of Mary Alice that says her real name is Angela.