Nick Mourouzis (April 16, 1937 – September 16, 2020) was an American football player and coach. He was the head football coach at DePauw University in Greencastle, Indiana from 1981 to 2003. He had a winning record of 133–82–4. As a college football player, Mourouzis was a starting quarterback at Miami University in Oxford, Ohio. Mourouzis was born in New Philadelphia, Ohio.