Human coronaviruses were discovered in the 1960s using two different methods. E.C. Kendall, Malcolm Bynoe, and David Tyrrel, working at the Common Cold Unit of the British Medical Research Council collected a unique common cold virus B814 in 1961. The virus could not be cultivated using the techniques which had successfully cultivated rhinoviruses, adenoviruses and other known common cold viruses. Eventually this was solved. The new cultivating method was introduced to the lab by Bertil Hoorn. The isolated virus when put into the noses of volunteers caused a cold. the virus was inactivated by ether which showed it had a lipid envelope. The novel virus caused a cold in volunteers and, like B814, was inactivated by ether.