William Leonard Pickard (born October 21, 1945) is an American writer, researcher and convicted drug trafficker. He is one of two people convicted in the largest lysergic acid diethylamide (LSD) manufacturing case in history. In 2000, while moving their LSD laboratory across Kansas, Pickard and Clyde Apperson were pulled over by police while driving a rental truck and a follow car. He was later sentenced to serve two life sentences. The DEA has claimed that Pickard's arrest led to a 95% drop in the availability of LSD in the US in the two years after his arrest.