The cell from which a virus buds often dies or is weakened. The lipid bilayer envelope of these viruses is sensitive to desiccation, heat, and detergents This makes it easier to sterile these viruses than non-enveloped viruses. They can not survive for very long outside host environments, and usually need to move directly from host to host. They are very adaptable and can change in a short time in order to evade the immune system. Enveloped viruses can cause persistent infections.