The most common naturally occurring isotope of hydrogen, known as protium, has a single proton and no neutrons. In ionic compounds, it can take on either a positive charge, becoming a cation composed of a bare proton, or a negative charge, becoming an anion known as a hydride. Hydrogen can form compounds with most elements and is present in water and most organic compounds. It plays a particularly important role in acid-base chemistry, in which many reactions involve the exchange of protons between soluble molecules. As the only neutral atom for which the Schrödinger equation can be solved analytically, study of the energetics and spectrum of the hydrogen atom has played a key role in the development of quantum mechanics.