Depression and anxiety have a negative impact on asthma. Comorbid anxiety with asthma is particularly confusing because of the similarity of symptoms and interference in perception and treatment of asthma. The National Asthma Council Australia recommends treatment for comorbid psychological symptoms. Cognitive Behaviour Therapy (CBT) is one recommended treatment for anxiety and depression. There is tentative research evidence suggesting that a program of CBT amended for asthma, delivered in conjunction with medical treatment and in close liaison with your medical team, can improve anxiety, asthma and quality of life. Clinicians intending to deliver CBT for comorbid asthma, anxiety or depression should refer to and the research reviewed by for guidance on safe and effective intervention.