Sanders was drafted by the Pittsburgh Steelers in the 3rd round (#82 overall) of the 2010 NFL Draft. With the Steelers, Sanders played as a solid backup behind Hines Ward, Antonio Brown, and Mike Wallace. Sanders missed a Week 9 game on November 6, 2011 against the Baltimore Ravens because his mother died. For his career, Sanders has a total of 50 catches for 664 yards and 4 touchdowns.