Angas Downs contains many different types of plants and habitats, including woodlands, gypsum depressions, limestone plains, spinifex, sand dunes, woodlands, alluvial floodplains and quartzite hills. Several species of native mammals including echidnas, the Ooldea dunnart, kultarr, red kangaroo, eastern wallaroo, Gould's wattled bat, lesser long-eared bat, spinifex hopping mouse, sandy inland mouse and dingos have been recorded on the Angas Downs. Mala were previously present in the area, but are no longer seen on the property.