Two studies of patients 80 years of age demonstrated improvements in quality of life, as assessed by the Seattle Angina Questionnaire.1131,1132 In 1 of these, angina relief and quality-of-life improvement scores after CABG did not differ between patients 75 and 75 years of age.1126 Of 136 octogenarians who underwent CABG, 81% felt that they were left with little or no disability in their daily activities, and 93% reported substantial symptomatic improvement an average of 2.1 years postoperatively.1131 Data on the influence of sex on CABG outcomes are limited. The BARI (Bypass Angioplasty Revascularization Investiga- tion) study compared the outcomes of 1829 patients with multivessel CAD randomly assigned to receive CABG or PCI; 27% were women.1133 Most information on the efficacy of CABG comes from studies done primarily in men, with extrapolation of the results to women. Although long-term outcomes with CABG in women are similar to or even better than those in men, women have higher rates of periprocedural morbidity and mortality.1133 1139 Several hypotheses have been suggested to explain this increased morbidity and mortality, including older age at presentation, more frequent need for urgent revascularization, more comorbid conditions, smaller body surface area and coronary arterial dimensions, and increased risk of bleeding. 