If these questions are answered with yes, the patient is considered a current smoker. Clinicians should avoid asking Are you a smoker? or Do you smoke? because people are less likely to report tobacco use when asked in 2. Tobacco users are more likely to quit after 6 months when clinicians strongly advise adults to quit using tobacco than when clinicians give no advice or usual care.S4.5-2 To help patients quit, it is critically important to use language that is clear and strong, yet compassionate, nonjudgmental, and personalized, to urge every tobacco user to For example, The most important thing you can do for your health is to quit tobacco use. I (we) can help. The ASCVD benefits of quitting The best and most effective treatments are those that are acceptable to and feasible for an individual patient; clinicians should consider the patient s specific medical history and preferences and offer to provide tailored strategies that work best for the patient.S4.5-3,S4.5-19 3. In alignment with previous expert consensus regarding strategies for tobacco cessation,S4.5-19 Table 8 summarizes recommended behavioral interventions and pharmacotherapy for tobacco treatment. There are 7 FDA-approved cessation medications, including 5 forms of nicotine replace- ment. Note that the black box warnings about neuropsychiatric events have been removed by the The net benefit of FDA-approved tobacco-cessation pharmacotherapy and behav- ioral interventions (even just 3 minutes of practical advice), alone or combined, in nonpregnant adults ( 18 years of age) who smoke is substantial. The net benefit of behavioral interventions for tobacco cessation on perinatal outcomes and smoking abstinence in pregnant women who smoke is substantial. However, the evidence on pharmaco- therapy for tobacco cessation in pregnant women is insufficient; the balance of benefits and harms cannot be determined. 