However, the Work Group is hesitant to recommend a DBP target because of the lack of evidence. Comparison with ACC/AHA guideline. The Work Group dis- cussed extensively the 2017 ACC/AHA guideline that offered a target of <130/<80 mm Hg for patients with CKD and analyzed the reasons provided in that guideline for this more conservative target, although the SBP target of <130 mm Hg is still more aggressive than those proposed by the European Society of Cardiology (ESC)/European Society of Hyperten- sion (ESH) (target: 130-139 mm Hg) and by NICE (target: One of the reasons was a concern that clinicians might apply the target to routine of ce BP readings. The KDIGO Work Group shares this concern but takes the view that patients should not be penalized for suboptimal clinical practice. One should not rely on routine of ce BP to adjust BP-lowering therapy. It should be noted that Hypertension Canada recommends an SBP target of <120 mm Hg using standardize BP measurement,159 consistent with the present guideline. The ACC/AHA guideline provides a table of equivalent BP values among standardized of ce, home, daytime ambulatory, night-time ambulatory, and 24-hour ambulatory measure- ments. These equivalents were established using an outcome- based approach that determines the BP threshold with each measurement technique that is associated with similar long- term outcomes in study populations.160 However, differ- ences in BP values obtained using different measurement techniques vary greatly among individual persons and even within a given individual over time. Thus, for any given in- dividual patient, the KDIGO Work Group found no evidence that one can reliably estimate the BP that would be obtained under standardized of ce conditions from measurements taken in any other settings. 