Treatment of Mild Hypertension Study Research Group. JAMA. 1993;270:713 24. S4.4-61. Julius S, Nesbitt SD, Egan BM, et al. Feasibility of treating prehy- pertension with an angiotensin-receptor blocker. N Engl J Med. 2006;354:1685 97. S4.4-62. Lawes CMM, Bennett DA, Lewington S, et al. Blood pressure and coronary heart disease: a review of the evidence. Semin Vasc Med. 2002;2:355 68. S4.4-63. Inder JD, Carlson DJ, Dieberg G, et al. Isometric exercise training for blood pressure management: a systematic review and meta-analysis to optimize benefit. Hypertens Res. 2016;39:88 94. S4.4-64. National Institute on Alcohol Abuse and Alcoholism. What Is A Standard Drink? Available at: https://www.niaaa.nih.gov/alco- hol-health/overview-alcohol-consumption/what-standard-drink. Accessed August 16, 2017. S4.4-65. National Heart, Lung, and Blood Institute. Your Guide to Lowering Your Blood Pressure With DASH How Do I Make the DASH? Available at: https://health.gov/dietaryguidelines/dga2005/toolkit/ DASH/how_make_dash.htm. Accessed January 6, 2019. S4.4-66. Top 10 Dash Diet Tips. Available at: http://dashdiet.org/dash-diet- tips.html. Accessed January 6, 2019. 4.5. Tobacco Use S4.5-1. Carson KV, Verbiest MEA, Crone MR, et al. Training health pro- fessionals in smoking cessation. Cochrane Database Syst Rev. 2012:CD000214. S4.5-2. Patnode CD, Henderson JT, Thompson JH, et al. Behavioral coun- seling and pharmacotherapy interventions for tobacco cessation in adults, including pregnant women: a review of reviews for the US Preventive Services Task Force. Ann Intern Med. 2015;163:608 21. S4.5-3. Stead LF, Koilpillai P, Fanshawe TR1, et al. Combined pharmacother- apy and behavioural interventions for smoking cessation. Cochrane Database Syst Rev. 2016;3:CD008286. S4.5-4. Pan A, Wang Y, Talaei M, et al. Relation of smoking with total mortality and cardiovascular events among patients with diabe- tes mellitus: a meta-analysis and systematic review. Circulation. 2015;132:1795 804. S4.5-5. Mons U, M ezzinler A, Gellert C, et al. 