Recommendations for Glucose Referenced studies that support recommendations are summarized in online Data Supplements 14 and 15. COR LOE Recommendations In patients with an ischemic stroke or TIA who also have diabetes, the goal for glycemic control should be individualized based on the risk for adverse events, patient characteris- tics and preferences, and, for most patients, especially those <65 years of age and without life-limiting comorbid illness, achieving a goal of HbA1c 7% is recommended to reduce risk for microvascular complications.229,230 In patients with an ischemic stroke or TIA who also have diabetes, treatment of diabetes should include glucose-lowering agents with proven cardiovascular benefit to reduce the risk for future major adverse cardiovas- cular events (ie, stroke, MI, cardiovascular In patients with an ischemic stroke or TIA who also have diabetes, multidimensional care (ie, lifestyle counseling, medical nutritional therapy, diabetes self-management education, support, and medication) is indicated to achieve glyce- mic goals and to improve stroke risk factors. In patients with prediabetes and ischemic stroke or TIA, lifestyle optimization (ie, healthy diet, regular physical activity, and smoking cessation) can be beneficial for the preven- tion of progression to diabetes.237,238 In patients with TIA or ischemic stroke, it is reasonable to screen for prediabetes/dia- betes using HbA1c which, among available methods (HbA1c, fasting plasma glucose, oral glucose tolerance), has the advantage of convenience because it does not require fast- ing and is measured in a single blood sample. 