Antiplatelet Therapy e403 4.4.2.2. Beta-Blocker Therapy e404 Aldosterone Blocker Therapy e405 4.4.2.4. Influenza Vaccination e406 4.4.2.5. Additional Therapy to Reduce Risk of MI and Death e407 4.4.3. Medical Therapy for Relief of Symptoms e408 4.4.3.1. Use of Anti-ischemic Medications: Recommendations e408 4.4.4. Alternative Therapies for Relief of Symptoms in Patients With Refractory Angina: Recommendations e411 4.4.4.1. Enhanced External Counterpulsation e412 4.4.4.2. Spinal Cord Stimulation e412 4.4.4.3. Acupuncture e413 5. CAD Revascularization e413 5.1. Heart Team Approach to Revascularization Decisions: Recommendations e413 5.2. Revascularization to Improve Survival: Recommendations e416 5.3. Revascularization to Improve Symptoms: Recommendations e417 5.4. CABG Versus Contemporaneous Medical Therapy e417 5.5. PCI Versus Medical Therapy e417 5.6. CABG Versus PCI e418 5.6.1. CABG Versus Balloon Angioplasty or BMS e418 5.6.2. CABG Versus DES e418 5.7. Left Main CAD e419 5.7.1. CABG or PCI Versus Medical Therapy for Left Main CAD e419 5.7.2. Studies Comparing PCI Versus CABG for Left Main CAD e419 5.7.3. Revascularization Considerations for Left Main CAD e419 5.8. Proximal LAD Artery Disease e420 5.9. Clinical Factors That May Influence the Choice of Revascularization e420 5.9.1. Completeness of Revascularization e420 5.9.2. LV Systolic Dysfunction e420 5.9.3. Previous CABG e421 5.9.4. Unstable Angina/Non ST-Elevation Myocardial Infarction e421 5.9.5. DAPT Compliance and Stent Thrombosis: Recommendation e421 5.10. Transmyocardial Revascularization e421 5.11. Hybrid Coronary Revascularization: Recommendations e421 5.12. Special Considerations e422 5.12.1. Women e422 5.12.2. Older Adults e423 5.12.3. Diabetes Mellitus e424 5.12.4. Obesity e425 5.12.5. Chronic Kidney Disease e425 5.12.6. HIV Infection and SIHD e426 5.12.7. Autoimmune Disorders e426 5.12.8. Socioeconomic Factors e426 5.12.9. Special Occupations e426 6. Patient Follow-Up: Monitoring of Symptoms and Antianginal Therapy e426 6.1. Clinical Evaluation, Echocardiography During Routine, Periodic Follow-Up: Recommendations e427 6.2. Follow-Up of Patients With SIHD e427 6.2.1. Focused Follow-Up Visit: Frequency e428 6.2.2. 