To that end, this CPG is intended to guide providers who care for patients with dyslipidemia along management pathways supported by evidence. The expected outcomes of successful implementation of this guideline include: Emphasizing the use of patient-centered care using risk factors and event history Minimizing preventable complications and morbidity Optimizing each individual s health outcomes and improving quality of life Assessing the patient s condition and collaborating with the patient, family, and caregivers to determine the optimal treatment Scope of the CPG This CPG is designed primarily to assist primary care providers (or other providers as applicable) in managing patients with dyslipidemia for the purpose of cardiovascular disease (CVD) risk reduction. This guideline seeks to inform providers with practical evidence-based recommendations for the most common scenarios involving patients at risk for CVD. A. Populations Included in this Guideline The patient population of interest for this CPG is patients >40 years old and eligible for care in the VA and/or DoD healthcare systems. B. Populations Excluded from this Guideline Patients with heart failure with reduced ejection fraction (EF) 35%, a limited life expectancy (<5 years), or end-stage renal disease (ESRD) were excluded from most clinical outcome trials. Although some controlled trial data exists exclusively in patients with ESRD and chronic systolic heart failure, the available evidence is comparatively sparse. Additionally, the data that is available show an absence of CV benefit in these populations. A more nuanced review of this evidence can be found in the 2014 iteration of the VA/DoD VA/DoD CPG for the Management of Dyslipidemia for Cardiovascular Risk Reduction Provider Summary Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction under section Populations Excluded from this Guideline. [3] Our updated systematic review found no new evidence that would alter this position. Genetic dyslipidemia conditions (e.g.