Effects of losartan in patients with a systemically functioning morphologic right ventricle after atrial repair of transposition of the great arteries. Am J Cardiol. 2001;88:1314 6. S3.17-8. Hechter SJ, Fredriksen PM, Liu P, et al. Angiotensin-converting en- zyme inhibitors in adults after the Mustard procedure. Am J Cardiol. 2001;87:660 3. A11. S3.17-9. Therrien J, Provost Y, Harrison J, et al. Effect of angiotensin receptor blockade on systemic right ventricular function and size: a small, ran- domized, placebo-controlled study. Int J Cardiol. 2008;129:187 92. S3.17-10. NGali N, Beghetti M, Gatzoulis MA, et al. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, dou- ble-blind, randomized, placebo-controlled study. Circulation. 2006;114:48 54. S3.17-11. Giardini A, Balducci A, Specchia S, et al. Effect of sildenafil on hae- modynamic response to exercise and exercise capacity in Fontan patients. Eur Heart J. 2008;29:1681 7. S3.17-12. Hebert A, Mikkelsen UR, Thilen U, et al. Bosentan improves ex- ercise capacity in adolescents and adults after Fontan operation: the TEMPO (Treatment With Endothelin Receptor Antagonist in Fontan Patients, a Randomized, Placebo-Controlled, Double-Blind Study Measuring Peak Oxygen Consumption) study. Circulation. 2014;130:2021 30. S3.17-13. Goldberg DJ, French B, McBride MG, et al. Impact of oral silden- afil on exercise performance in children and young adults after the Fontan operation: a randomized, double-blind, placebo-controlled, crossover trial. Circulation. 2011;123:1185 93. 4. SPECIFIC LESIONS 4.1. Shunt Lesions 4.1.1. Atrial Septal Defect S4.1.1-1. Oster M, Bhatt A, Zaragoza-Macias E, et al. Interventional therapy versus medical therapy for secundum atrial septal defect: a systematic review (part 2) for the 2018 AHA/ACC guideline for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019;139:e000 000. S4.1.1-2. Ammash NM, Seward JB, Warnes CA, et al. 