SOS score: an opti- mized score to screen acute stroke patients for obstructive sleep apnea. Sleep Med. 2014;15:1021 1024. doi: 10.1016/j.sleep.2014.03.026 370. Stahl SM, Yaggi HK, Taylor S, Qin L, Ivan CS, Austin C, Ferguson J, Radulescu R, Tobias L, Sico J, et al. Infarct location and sleep apnea: evaluating the potential association in acute ischemic stroke. Sleep Med. P rez-Ronchel J, Dur n-Cantolla J, de la Torre G, Gonz lez Marcos JR, de la Pe a M, et al. Early treatment of obstructive apnoea and stroke out- come: a randomised controlled trial. Eur Respir J. 2011;37:1128 1136. 372. McEvoy RD, Antic NA, Heeley E, Luo Y, Ou Q, Zhang X, Mediano O, Chen R, Drager LF, Liu Z, et al; SAVE Investigators and Coordinators. CPAP for prevention of cardiovascular events in obstructive sleep apnea. N Engl J Med. 2016;375:919 931. doi: 10.1056/NEJMoa1606599 373. C t R, Zhang Y, Hart RG, McClure LA, Anderson DC, Talbert RL, Benavente OR. ASA failure: does the combination ASA/clopidogrel confer better long-term vascular protection? Neurology. 2014;82:382 374. Lee M, Saver JL, Hong KS, Rao NM, Wu YL, Ovbiagele B. Antiplatelet regimen for patients with breakthrough strokes while on aspirin: a sys- tematic review and meta-analysis. Stroke. 2017;48:2610 2613. doi: 375. John S, Katzan I. Recurrent stroke while on antiplatelet therapy. Neurol 376. Turan TN, Maidan L, Cotsonis G, Lynn MJ, Romano JG, Levine SR, ChimowitzMI;fortheWarfarin-AspirinSymptomaticIntracranialDisease Investigators. Failure of antithrombotic therapy and risk of stroke in patients with symptomatic intracranial stenosis. Stroke. 2009;40:505 377. Kasner SE, Lynn MJ, Chimowitz MI, Frankel MR, Howlett-Smith H, Hertzberg VS, Chaturvedi S, Levine SR, Stern BJ, Benesch CG, et al; Warfarin Aspirin Symptomatic Intracranial Disease (WASID) Trial Investigators. Warfarin vs aspirin for symptomatic intracranial stenosis: subgroup analyses from WASID. Neurology. 378. 