HBPM should be performed for 7 days (not less than 3), with duplicate morning and evening measurements after 5 mi- nutes of sitting at rest and 1 minute between measurements (total of at least 12 readings per week). These preparations have been suggested to be useful in the initial evaluation of untreated children with suspected hypertension, and for children with treated hypertension before each follow-up visit to the healthcare provider.365 The advantages of HBPM include the ability to obtain multiple BP measure- ments outside the of ce setting, its relative ease of use, and perhaps higher acceptance by patients and families. Similar to standardized of ce BP measurements and in contrast to ABPM, however, no prospective RCTs targeting HBPM to improve clinical outcomes are available in children. Reliable factors converting standardized of ce BP to home BP or ABPM are also not available in children. Additionally, clin- ical validation of newer, more automated BP devices in children is necessary. Quality of evidence. The quality of the evidence is low for the outcomes of annual GFR loss and ESKD, as the recom- mendation of a target of <50th percentile MAP by ABPM in children was based on a single RCT with study limitations (Supplementary Table S40142 ). The quality of the evidence for the mortality outcome was very low because of study limi- tations and very serious imprecision because death is a rare event in children. Nonetheless, multiple smaller interven- tional trials and observational studies with multiple mean- ingful outcomes for children have consistently shown bene ts of BP lowering. 