All rights reserved. Subject to Notice of rights. ISBN: Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE) Relative effect Anticipated absolute effects Risk with Clinical monitoring Risk difference with NP monitoring (95% CI) indirectness, imprecision HF hospitalisation (RR) - All ages VERY LOWb,c,d due to risk of bias, indirectness, imprecision (from 395 fewer to 15 more) HF hospitalisation (Rate Ratio) All ages VERY LOWb,c,d due to risk of bias, indirectness, imprecision Rate ratio 618 events per 1000 person years 161 more events per 1000 person years (from 49 more to 297 more) Quality of life MLWHFQ final 462 MODERATEb due to risk of bias The mean quality of life (MLWHFQ) in the control groups was The mean quality of life(MLWHFQ) in the intervention groups was (2.23 lower to 5.02 higher) Quality of life - KCCQ change 250 LOWb due to risk of bias The mean quality of life (KCCQ) in the control groups was The mean quality of life (KCCQ)in the intervention groups was (7.19 lower to 1.99 higher) Quality of life SF36 physical final VERY LOW b,i due to risk of bias, inconsistency The mean quality of life (SF36 physical) in the control groups was The mean quality of life (SF36 physical) in the intervention groups was (5.13 lower to 4.47 higher) Quality of life SF36 mental final MODERATEb due to risk of bias The mean quality of life (SF36 mental) in the control groups was The mean quality of life (SF36 mental) in the intervention groups was (1.9 lower to 2.02 higher) Renal function - All ages eGFR, creatinine clearance MODERATEb The mean eGFR in the control group was The mean eGFR in the intervention groups was 0.76 ml/min lower Monitoring Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. 