Of occurred in women.1 Bushnell et al Guidelines for Prevention of Stroke in Women 1547 Incidence Ischemic Stroke Within most age strata, women have a lower IS incidence than men, and as such, the overall age-adjusted incidence of IS is lower for women than men4,24,26 31 ; however, sex differences in IS incidence rates differ across the age strata. In the oldest age groups (generally >85 years of age), women tend to have or similar incidence of IS as men.4,26 Because women tend to be older when they have their stroke events, and women have a longer life expectancy than men, age- adjusted rates can be misleading and may underestimate the total burden of stroke in women. Differences by race/ethnicity have also been noted, with higher rates among blacks and than among whites for both women and men.1,28 31 Hemorrhagic Stroke (SAH and ICH) The majority of studies show that women have higher rates of SAH incidence than men26,32 43 ; however, sex differences are modified by age such that SAH rates are higher in men at younger ages but higher in women relative to men begin- ning at 55 years of age.44,45 Data reported from non-US populations have shown differing sex-related patterns across countries, with higher SAH incidence among men in Finland and eastern Europe, possibly because of regional differences in risk factor prevalence in men and women.46 The incidence Table 1. Applying Classification of Recommendation and Level of Evidence A recommendation with Level of Evidence B or C does not imply that the recommendation is weak. Many important clinical questions addressed in the guidelines do not lend themselves to clinical trials. Although randomized trials are unavailable, there may be a very clear clinical consensus that a particular test or therapy is useful or effective. 