Minor changes since publication July 2022: Recommendations 1.4.48 to 1.4.50 have been updated in line with NICE's technical appraisal guidance on icosapent ethyl with statin therapy for reducing the risk of cardiovascular events in people with raised triglycerides. April 2022: Changed heading for recommendations 1.4.3 to 1.4.11 to clarify that these cover initial lipid measurement and referral for specialist review. January 2022: Minor changes to redirect NICE Pathways links. November 2021: We added a link to NICE's shared decision making guideline in recommendation 1.1.22. October 2021: We added a link to other treatment options in NICE's technology appraisal guidance on lipid disorders (see end of recommendations section). November 2020: The link in recommendations 1.3.7 and 1.3.8 was replaced with a link to the 2019 UK Chief Medical Officers' physical activity guideline. Footnotes were incorporated into the text and the table in appendix A redrawn in line with accessibility guidance. June 2020: The recommendation on alcohol consumption was updated to bring it in line with the UK chief medical officers' guidelines on low-risk drinking. Links were added to the patient decision aid on taking a statin to reduce the risk of coronary heart disease and stroke. August 2018: A link to the NICE guideline on physical activity: exercise referral schemes was added to recommendation 1.4.15. February 2018: In recommendation 1.1.20, a link was updated to go to the NICE guideline on obesity. In recommendation 1.3.10, links were updated to go to the NICE guidelines on walking and cycling, physical activity, and exercise referral schemes to promote physical activity. In recommendation 1.3.12, a link was updated to go to the NICE guideline on obesity. In recommendation 1.4.13, a link was updated to go to the NICE guideline on obesity. 