A relationship is considered to be significant if (1) the person receives $10000 or more during any 12-month period, or 5% or more of the person s gross income; or (2) the person owns 5% or more of the voting stock or share of the entity, or owns $10000 or more of the fair market value of the entity. A relationship is considered to be modest if it is less than significant under the preceding definition. *Modest. Significant. Bushnell et al Guidelines for Prevention of Stroke in Women 1577 References 1. Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Franco S, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Huffman MD, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Magid D, Marcus GM, Marelli A, Matchar DB, McGuire DK, Mohler ER, Moy CS, Mussolino ME, Nichol G, Paynter NP, Schreiner PJ, Sorlie PD, Stein J, Turan TN, Virani SS, Wong ND, Woo D, Turner MB; on behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics 2013 update: a report from the American Heart Association [published corrections appear in Circulation. 2013;127:e841 and Circulation. 2013;127]. Circulation. 2013;127:e6 e245. 2. National Center for Health Statistics. Health, United States, 2011. Hyattsville, MD: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics; 2012. http://www.cdc.gov/nchs/hus/contents2011.htm#031. Accessed December 31, 2012. 3. US Department of Health and Human Services, Administration on Aging. A profile of older Americans: 2011. http://www.aoa.gov/AoAroot/Aging_ Statistics/Profile/2011/docs/2011profile.pdf. Accessed March 6, 2013. 4. Reeves MJ, Bushnell CD, Howard G, Gargano JW, Duncan PW, Lynch G, Khatiwoda A, Lisabeth L. Sex differences in stroke: epidemiol- ogy, clinical presentation, medical care, and outcomes. Lancet Neurol. 