Typically, a clinic BP of 140/90 mm Hg corresponds to home BP values of 135/85 mm Hg and toABPM values defined as a daytime SBP/DBP of 135/85 mm Hg, a nighttime SBP/DBP of 120/70 mm Hg, and These thresh- olds are based on data from European, Australian, and Asian populations, with few data available for establishing appropri- ate thresholds for US populations.S4.3-9 S4.3-13 They are provided as a guide but should be interpreted with caution. Higher day- time SBP measurements from ABPM can be associated with an increased risk of CVD and all-cause death independent of clinic-measured BP.S4.3-14 A meta-analysis of observational studies that included 13844 individuals suggested nighttime BP is a stronger risk factor for CHD and stroke than either clinic or daytime BP.S4.3-15 Methodological issues complicate the interpretation of data from studies that report office and out-of-office BP read- ings. Definitions and diagnostic methods for identifying white coat hypertension and masked hypertension (see Section 4.4) have not been standardized. The available studies have dif- fered with regard to number of office readings obtained, use of 24-hour ABPM, use of daytime-only ABPM, inclusion of day- time and nighttime BP readings as separate categories, HBPM Table 11. Corresponding Values of SBP/DBP for Clinic, HBPM, Daytime, Nighttime, and 24-Hour ABPM Measurements Clinic HBPM Daytime ABPM Nighttime ABPM ABPM ABPM indicates ambulatory blood pressure monitoring; BP, blood pressure; DBP, diastolic blood pressure; HBPM, home blood pressure monitoring; and SBP, systolic blood pressure. Table 10. Procedures for Use of HBPMS4.2 5 S4.2 7 Patient training should occur under medical supervision, including: Information about hypertension Selection of equipment Acknowledgment that individual BP readings may vary substantially Interpretation of results Devices: Verify use of automated validated devices. 