Hosono M, SasakiY, Hirai H, Sakaguchi M, NakahiraA, Seo H, Morisaki A, Suehiro S. Considerations in timing of surgical intervention for infec- tive endocarditis with cerebrovascular complications. J Heart Valve Dis. 2010;19:321 325. 270. Ruttmann E, Willeit J, Ulmer H, Chevtchik O, H fer D, Poewe W, Laufer G, M ller LC. Neurological outcome of septic cardioembolic stroke after infective endocarditis. Stroke. 2006;37:2094 2099. doi: 10.1161/01. STR.0000229894.28591.3f. 271. Snygg-Martin U, Gustafsson L, Rosengren L, Alsi A, Ackerholm P, Andersson R, Olaison L. Cerebrovascular complications in patients with left-sided infective endocarditis are common: a prospective study using magnetic resonance imaging and neurochemical brain damage markers. Clin Infect Dis. 2008;47:23 30. doi: 10.1086/588663. 272. Thuny F, Avierinos JF, Tribouilloy C, Giorgi R, Casalta JP, Milandre L, Brahim A, Nadji G, Riberi A, Collart F, Renard S, Raoult D, Habib G. Impact of cerebrovascular complications on mortality and neuro- logic outcome during infective endocarditis: a prospective multicen- tre study. Eur Heart J. 2007;28:1155 1161. doi: 10.1093/eurheartj/ ehm005. 273. Barsic B, Dickerman S, Krajinovic V, Pappas P, Altclas J, Carosi G, Casab JH, Chu VH, Delahaye F, Edathodu J, Fortes CQ, Olaison L, Pangercic A, Patel M, Rudez I, Tamin SS, Vincelj J, Bayer AS, Wang A; International Collaboration on Endocarditis Prospective Cohort Study Investigators. Influence of the timing of cardiac surgery on the outcome of patients with infective endocarditis and stroke. Clin Infect Dis. 2013;56:209 217. doi: 10.1093/cid/cis878. R, Noureddine M, PlataA, Lomas JM, G lvez-Acebal J, Hidalgo-Tenorio C, Ru z-Morales J, Mart nez-Marcos FJ, Reguera JM, de la Torre-Lima J, deAlarc n Gonz lezA; Group for the Study of Cardiovascular Infections of the Andalusian Society of Infectious Diseases; Spanish Network for Research in Infectious Diseases. 