The Lewin Team, including The Lewin Group, Anjali Jain Research & Consulting, Duty First Consulting, ECRI, and Sigma Health Consulting, was contracted by the VA and DoD to support the development of this CPG and conduct the systematic evidence review. In January 2019, the contracting officer s representative (COR), leaders from the VA Office of Quality and Patient Safety and the DoD Office of Evidence Based Practice, and the Champions kicked off the guideline development effort. During this teleconference, participants discussed the guideline initiative s scope, the Champions roles and responsibilities, the project timeline, and the approach for developing and prioritizing specific research questions (i.e., key questions) on which to base a systematic evidence review about the management of patients with dyslipidemia. The specialties and clinical areas of interest included: primary care, cardiology, nursing, clinical pharmacology, internal medicine, family practice, exercise physiology, and dietetics. The guideline development process for the 2020 CPG update included: 1. Formulating and prioritizing KQs 2. Convening a patient focus group 3. Conducting the systematic evidence review 4. Convening a face-to-face meeting with the CPG Champions and Work Group members to review the evidence, craft evidence-based recommendations, and develop an algorithm 5. Drafting and submitting a final CPG on the management of dyslipidemia to the VA/DoD EBPWG a. Grading Recommendations The Champions and Work Group used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to assess the quality of the evidence base and assign a strength for each recommendation. The GRADE system uses these four domains to assess the strength of each Balance of desirable and undesirable outcomes Confidence in the quality of the evidence Values and preferences Other implications, as appropriate, e.g.