Reproduced with permission from Grundy et al.S4.3-1 Copyright 2018, American Heart Association, Inc., and American College of Cardiology Foundation. Recommendations for Adults With High Blood Cholesterol (Continued) COR LOE Recommendations CLINICAL STATEMENTS AND GUIDELINES I SBP:B-RSR In adults with confirmed hypertension and a 10-year ASCVD event risk of 10% or higher, a BP target of less than 130/80 mm Hg is Adapted from recommendations in the 2017 Hypertension Clinical Practice Guidelines.S4.4-1 DBP:C-EO I SBP:B-RSR In adults with hypertension and chronic kidney disease, treatment to a BP goal of less than 130/80 mm Hg is Adapted from recommendations in the 2017 Hypertension Clinical Practice Guidelines.S4.4-1 DBP:C-EO I SBP:B-RSR In adults with T2DM and hypertension, antihypertensive drug treatment should be initiated at a BP of 130/80 mm Hg or higher, with a treatment goal of less than 130/80 Adapted from recommendations in the 2017 Hypertension Clinical Practice Guidelines.S4.4-1 DBP:C-EO I C-LD In adults with an estimated 10-year ASCVD risk <10% and an SBP of 140 mm Hg or higher or a DBP of 90 mm Hg or higher, initiation and use of BP-lowering medication Adapted from recommendations in the 2017 Hypertension Clinical Practice Guidelines.S4.4-1 IIb SBP:B-NR In adults with confirmed hypertension without additional markers of increased ASCVD risk, a BP target of less than 130/80 mm Hg may be reasonable.S4.4-59 S4.4-62 Adapted from recommendations in the 2017 Hypertension Clinical Practice DBP:C-EO *ACC/AHA pooled cohort equations to estimate 10-year risk of ASCVD. See Figure 4 for the BP thresholds and treatment rec- ommendations algorithm and refer to the 2017 Hyper- tension Clinical Practice Guidelines for comprehensive See Table 7 for recommended dose and approximate impact on SBP. 4.5. Treatment of Tobacco Use Recommendations for Treatment of Tobacco Use Referenced studies that support recommendations are summarized in Online Data Supplements 15 and 16. 