The cause of ischemic stroke remains unknown in 20% to 40% of patients, leading to a diag- nosis of cryptogenic stroke. Prolonged electrocar- diogram monitoring with an implantable cardiac monitor in these patients (age >40 years) has the advantage of increasing the likelihood of detect- ing silent AF that would escape detection with short-term monitoring. A recent RCT established CLINICAL STATEMENTS AND GUIDELINES the superiority of an implantable cardiac monitor over conventional monitoring for detecting silent AF, a finding with major clinical ramifications for A role in screening for silent AF may also exist for remote electrocardiographic acquisition and transmission with a smart worn or handheld WiFi-enabled device with remote 7.13. Weight Loss (New) Recommendation for Weight Loss in Patients with AF Referenced studies that support the new recommendation are summarized in Online Data Supplement 10. COR LOE Recommendation I B-R For overweight and obese patients with AF, weight loss, combined with risk factor modification, is recommended.S7.13-1 S7.13-3 NEW: New data demonstrate the beneficial effects of weight loss and risk factor modification on controlling AF. Recommendation-Specific Supportive Text (New) 1. Obesity is associated with atrial electrostructural One RCT dem- onstrated that a structured weight management program for obese patients (body mass index >27) with symptomatic AF reduced symptom burden and severity and reduced the number of AF episodes and their cumulative duration when compared with attempts to optimally manage risk factors alone.S7.13-1 Risk factor modification included assessment and treatment of underly- ing sleep apnea, hypertension, hyperlipidemia, glucose intolerance, and alcohol and tobacco use. 