2010;31:2103 10. 538. Ho PM, Peterson ED, Wang L, et al. Incidence of death and acute myocar- dial infarction associated with stopping clopidogrel after acute coronary syndrome. JAMA. 2008;299:532 9. Erratum in: JAMA. 2008;299:2390. 539. Rao SV, Jollis JG, Harrington RA, et al. Relationship of blood transfu- sion and clinical outcomes in patients with acute coronary syndromes. JAMA. 2004;292:1555 62. 540. Koch CG, Li L, Sessler DI, et al. Duration of red-cell storage and compli- cations after cardiac surgery. N Engl J Med. 2008;358:1229 39. 541. Dangas G, Mehran R, Guagliumi G, et al. Role of clopidogrel loading dose in patients with ST-segment elevation myocardial infarction under- going primary angioplasty: results from the HORIZONS-AMI (Harmo- nizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) trial. J Am Coll Cardiol. 2009;54:1438 46. 542. Lincoff AM, Bittl JA, Harrington RA, et al. Bivalirudin and provisional glycoprotein IIb/IIIa blockade compared with heparin and planned gly- coprotein IIb/IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial. JAMA. 2003;289:853 63. Erratum in: JAMA. 2003;289:1638. 543. Alexander KP, Chen AY, Roe MT, et al. Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes. JAMA. 2005;294:3108 16. Erratum in: JAMA. 2006;295:628. 544. Eikelboom JW, Mehta SR, Anand SS, et al. Adverse impact of bleed- ing on prognosis in patients with acute coronary syndromes. Circulation. 2006;114:774 82. 545. Rao SV, O Grady K, Pieper KS, et al. A comparison of the clinical im- pact of bleeding measured by two different classifications among patients with acute coronary syndromes. J Am Coll Cardiol. 2006;47:809 16. 546. Manoukian SV, Feit F, Mehran R, et al. Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes: an analysis from the ACUITY Trial. J Am Coll Cardiol. 2007;49:1362 8. 