Critical outcomes median was rated 7 9, and important outcomes were rated 4 6 on the 9-point scale. www.kidney-international.org methods for guideline development Table 2| Clinical questions and systematic review topics in the PICOM format Guideline Chapter 1 Blood pressure measurement Clinical question In patients with CKD, what is the diagnostic accuracy of various BP measurement techniques compared to standardized auscultatory of ce-based BP? Population Patients with CKD (CKD G1 G5 without kidney transplant, and kidney transplant recipients) Index test Oscillometric (of ce-based) BP (unattended or attended), ambulatory BP, home oscillometric monitors Reference standard Auscultatory of ce-based BP monitoring Outcomes Sensitivity, speci city, negative predictive value, positive predictive value Study design Systematic reviews SoF table Supplementary Table S41 Clinical question In the general population, what is the diagnostic accuracy of various BP measurement techniques (oscillometric of ce and home BP, ambulatory BP) compared to standardized auscultatory of ce-based BP in diagnosing high BP? Population General population Index test Oscillometric (of ce-based) BP (unattended or attended), ambulatory BP, home oscillometric monitors Reference standard Auscultatory of ce-based BP monitoring Outcomes Sensitivity, speci city, negative predictive value, positive predictive value Study design Systematic reviews SoF table Supplementary Tables S4, S42, and S43 Clinical question In the general population, what is the association among various approaches to measuring BP including in the clinic (standardized vs. non-standardized), at home, and ambulatory with classi cation of BP and long-term outcomes? 