Recommendations were revised in a multistep process during a face-to-face meeting (New Orleans, LA, USA, January 2019) and by e-mail communication. The nal draft was sent for external public review, and reviewers provided open-ended responses. Based on the external stakeholder feedback, the draft was further revised by Work Group Co-Chairs and members. All Work Group members provided feedback on initial and nal drafts of the recommendation statement and guideline text and approved the nal version of the guideline. The ERT also provided a descriptive Primary evidence Search October 2018, updated September 2019, updated April 2020 Cochrane Kidney and Transplant Registry, MEDLINE, Embase - 6156 study reports retrieved - 148 observational studies Included RCTs Dietary protein 21 RCTs Dietary and supplementary salt 30 RCTs Dietary patterns 5 RCTs Exercise interventions 11 RCTs Blood pressure targets in CKD 11 RCTs Renin angiotensin system inhibitors in adults 76 RCTs Non-renin angiotensin system inhibitors 37 RCTs Blood pressure targets in transplant recipients 1 RCT Antihypertensive therapy in transplant recipients 82 RCTs Blood pressure targets in children 1 RCT Antihypertensive therapy in children 2 RCTs Potassium binders 13 RCTs Included studies 290 RCTs (n 61000) Systematic reviews - 7 CKD narrative reviews - 3 general population diagnostic test accuracy reviews - 20 general population narrative reviews - 5 general population cost-effectiveness reviews 14 observational studies Full-text screening 524 citations excluded Systematic reviews of blood pressure measurement techniques Search February 2019, updated April 2020 Cochrane Kidney and Transplant Registry - 559 reports retrieved Figure 8 | Search yield and study ow diagram. CKD, chronic kidney disease; RCT, randomized controlled trial. Table 3| Classi cation for certainty and quality of the evidence Grade Quality of evidence Meaning A High We are con dent that the true effect is close to the estimate of the effect. 