Kanafani ZA, Federspiel JJ, Fowler VG Jr. Infective endocarditis caused by daptomycin-resistant Enterococcus faecalis: a case report. Scand J Infect Dis. 2007;39:75 77. doi: 10.1080/00365540600786465. 211. Schutt AC, Bohm NM. Multidrug-resistant Enterococcus faecium endo- carditis treated with combination tigecycline and high-dose daptomycin. Ann Pharmacother. 2009;43:2108 2112. doi: 10.1345/aph.1M324. 212. Casapao AM, Kullar R, Davis SL, Levine DP, Zhao JJ, Potoski BA, Goff DA, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. Multicenter study of high-dose daptomycin for treatment of enterococ- cal infections. Antimicrob Agents Chemother. 2013;57:4190 4196. doi: 10.1128/AAC.00526-13. 213. Hall AD, Steed ME, Arias CA, Murray BE, Rybak MJ. Evaluation of standard- and high-dose daptomycin versus linezolid against vancomy- cin-resistant Enterococcus isolates in an in vitro pharmacokinetic/phar- macodynamic model with simulated endocardial vegetations. Antimicrob Agents Chemother. 2012;56:3174 3180. doi: 10.1128/AAC.06439-11. 214. Sakoulas G, Nonejuie P, Nizet V, Pogliano J, Crum-Cianflone N, Haddad F. Treatment of high-level gentamicin-resistant Enterococcus faeca- lis endocarditis with daptomycin plus ceftaroline. Antimicrob Agents Chemother. 2013;57:4042 4045. doi: 10.1128/AAC.02481-12. Baddour et al Infective Endocarditis in Adults 1483 215. Sakoulas G, Rose W, Nonejuie P, Olson J, Pogliano J, Humphries R, Nizet V. Ceftaroline restores daptomycin activity against dapto- mycin-nonsusceptible vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2014;58:1494 1500. doi: 10.1128/ AAC.02274-13. 216. Sakoulas G, Bayer AS, Pogliano J, Tsuji BT, Yang SJ, Mishra NN, Nizet V, Yeaman MR, Moise PA. Ampicillin enhances daptomycin- and cat- ionic host defense peptide-mediated killing of ampicillin- and vanco- mycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2012;56:838 844. doi: 10.1128/AAC.05551-11. 217. Kullar R, Casapao AM, Davis SL, Levine DP, Zhao JJ, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. A multicentre evaluation of the effectiveness and safety of high-dose daptomycin for the treatment of infective endocarditis. J Antimicrob Chemother. 2013;68:2921 2926. doi: 10.1093/jac/dkt294. 218. Geraci JE, Wilson WR. 