Organization of the Writing Committee The writing committee consisted of medical experts including cardiologists, internists, interventionalists, a nurse practitioner, pharmacists, a physician assistant, a pediatrician, a nephrologist, and a lay/patient repre- sentative. The writing committee included represen- tatives from the American Heart Association (AHA), American College of Cardiology (ACC), American Association of Cardiovascular and Pulmonary Reha- bilitation (AACVPR), American Association Academy of Physician Assistants (AAPA), Association of Black Cardiologists (ABC), American College of Preventive Medicine (ACPM), American Diabetes Association (ADA), American Geriatrics Society (AGS), American Pharmacists Association (APhA), American Society for Preventive Cardiology (ASPC), National Lipid As- sociation (NLA), and Preventive Cardiovascular Nurses Association (PCNA). Appendix 1 of the present docu- ment lists writing committee members relevant re- lationships with industry and other entities. For the purposes of full transparency, the writing committee members comprehensive disclosure information is available online. 1.3. Document Review and Approval This document was reviewed by 21 official reviewers each nominated by the ACC, AHA, AAPA, ABC, ACPM, ADA, AGS, APhA, ASPC, NLA, and PCNA, as well as 27 individual content reviewers. Reviewers RWI informa- tion was distributed to the writing committee and is published in this document (Appendix 2). This document was approved for publication by the governing bodies of the AHA, the ACC, AAPA, ABC, ACPM, ADA, AGS, APhA, ASPC, NLA, and PCNA. 1.4. Scope of the Guideline The purpose of the present guideline is to address the practical management of patients with high blood cholesterol and related disorders. The writing com- mittee reviewed previously published guidelines, evi- dence reviews, and related statements. Table S1 in the Web Supplement contains a list of publications and statements deemed pertinent. The primary sources of evidence are randomized controlled trials (RCTs). 