e136 10.2.3. Intervention for Mixed MS and MR . . . e137 10.2.4. Intervention for Mixed MS and AR . . . e137 10.2.5. Intervention for Mixed MS and AS . . . e137 11. Prosthetic Valves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . e137 11.1. Evaluation and Selection of Prosthetic Valves . e137 11.1.1. Diagnosis and Follow-Up of Prosthetic Valves . . . . . . . . . . . . . . . . . . . . . . . . . . . e137 11.1.2. Selection of Prosthetic Valve Type: Bioprosthetic Versus Mechanical Valve . e139 11.2. Antithrombotic Therapy . . . . . . . . . . . . . . . . . . . e142 11.3. Bridging Therapy e146 11.4. Excessive Anticoagulation and Serious Bleeding With Prosthetic Valves . . . . . . . . . . . . e148 11.5. Thromboembolic Events With Prosthetic Valves . e148 11.6. Acute Mechanical Valve Thrombosis . . . . . . . . e149 11.6.1. Diagnosis of Acute Mechanical Valve Thrombosis . . . . . . . . . . . . . . . . . . . . . . e149 11.6.2. Intervention . . . . . . . . . . . . . . . . . . . . . e150 11.7. Bioprosthetic Valve Thrombosis . . . . . . . . . . . . . e150 11.7.1. Diagnosis of Bioprosthetic Valve Thrombosis . . . . . . . . . . . . . . . . . . . . . . e150 11.7.2. Medical Therapy . 