Treating Heart Failure Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: Table 30: Clinical Evidence summary: Low sodium diet versus moderate sodium diet for heart failure Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE) Relative effect Anticipated absolute effects Time frame is 6 months Risk with Advice for moderate sodium diet Risk difference with Advice for low sodium diet (95% CI) Quality of Life Kansas City Cardiomyopathy Questionnaire. Scale from: 0 to 100. High is better LOWa,b due to risk of bias The median quality of life in the control groups was The median quality of life in the intervention groups was Renal function Creatinine (umol/L) LOWa,b, due to risk of bias The median renal function in the control groups was The median renal function in the intervention groups was (a) Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the evidence was at very high risk of bias. (b) Imprecision cannot assessed due to reporting of median and inter-quartile range. Table 31: Clinical evidence summary: Fluid restriction programme versus advice on fluid restriction for heart failure Outcomes No of Participant s (studies) Follow up Quality of the evidence (GRADE) Relative effect Anticipated absolute effects Time frame is 6 months Risk with Advice on fluid restriction Risk difference with Programme for fluid restriction (95% CI) Quality of Life EQ5D - visual analogue scale. Scale from: 0 to 100. High is better. VERY LOWa,b,c due to risk of bias, indirectness, imprecision The mean quality of life at 6 months in the control groups was The mean quality of life at 6 months in the intervention groups was (24.96 lower to 7.6 higher) Oedema Congestion score. 