Ninomiya JK, L Italien G, Criqui MH, Whyte JL, Gamst A, Chen RS. Association of the metabolic syndrome with history of myocardial infarc- tion and stroke in the Third National Health and Nutrition Examination Survey. Circulation. 2004;109:42 46. 644. Milionis HJ, Rizos E, Goudevenos J, Seferiadis K, Mikhailidis DP, Elisaf MS. Components of the metabolic syndrome and risk for first- ever acute ischemic nonembolic stroke in elderly subjects. Stroke. 2005;36:1372 1376. 645. Park YK, Yi HJ, Lee YJ, Cho H, Chun HJ, Oh SJ. The relationship between metabolic syndrome (MetS) and spontaneous intracerebral hemorrhage (ICH). Neurol Sci. 2013;34:1523 1528. 646. Novo S, Peritore A, Guarneri FP, Corrado E, Macaione F, Evola S, Novo G. Metabolic syndrome (MetS) predicts cardio and cerebrovascular events in a twenty years follow-up: a prospective study. Atherosclerosis. 2012;223:468 472. 647. Chen HJ, Bai CH, Yeh WT, Chiu HC, Pan WH. Influence of metabolic syndrome and general obesity on the risk of ischemic stroke. Stroke. 2006;37:1060 1064. 648. Koren-Morag N, Goldbourt U, Tanne D. Relation between the metabolic syndrome and ischemic stroke or transient ischemic attack: a prospec- tive cohort study in patients with atherosclerotic cardiovascular disease. Stroke. 2005;36:1366 1371. 649. Kurl S, Laukkanen JA, Niskanen L, Laaksonen D, Sivenius J, Nyyssonen K, Salonen JT. Metabolic syndrome and the risk of stroke in middle-aged men. Stroke. 2006;37:806 811. 650. Najarian RM, Sullivan LM, Kannel WB, Wilson PW, D Agostino RB, Wolf PA. Metabolic syndrome compared with type 2 diabetes mellitus as a risk factor for stroke: the Framingham Offspring Study. Arch Intern Med. 2006;166:106 111. 651. Mottillo S, Filion KB, Genest J, Joseph L, Pilote L, Poirier P, Rinfret S, Schiffrin EL, Eisenberg MJ. The metabolic syndrome and cardiovas- cular risk a systematic review and meta-analysis. J Am Coll Cardiol. 2010;56:1113 1132. 652. 