LOE amended to conform with ACC/AHA 2015 Recommendation Classification System. See Table XCV in online Data Supplement 1 for original wording. A multidisciplinary quality improvement committee, as 1 part of a quality improvement process, was associated with improved timeliness of IV alteplase administration after AIS, lower in-hospital mortality and intracranial hemorrhage rates, and an increase in the percentage of patients discharged home.53,69 Identification of stroke treatment barriers with targeted interventions has demonstrated benefit in improving stroke treatment in community hospitals.45 See Tables VI, VII, and XIV in online Data Supplement 1. 2. Stroke outcome measures should include adjustments for baseline severity. I B-NR Recommendation revised from 2013 Stroke Systems of Care. COR and LOE added to conform with ACC/AHA 2015 Recommendation Classification System. Continuous quality improvement processes, implemented by each major element of a stroke system of care and the system as a whole, can be useful in improving patient care or outcomes. IIa B-NR Recommendation revised from 2013 Stroke Systems of Care. COR and LOE added to conform with ACC/AHA 2015 Recommendation Classification System. Data indicate that continuous quality improvement efforts along the stroke spectrum of care, from initial patient identification to EMS activation, ED evaluation, stroke team activation, and poststroke care, can be useful in improving Stroke outcome measures are strongly influenced by baseline stroke severity as measured by the National Institutes of Health Stroke Scale (NIHSS).70 73 Other identified predictors of poor outcomes include age, blood glucose, and infarct on imaging.73 Quality improvement efforts should recognize these predictors in order to have meaningful comparisons between stroke care systems. See Tables VI, VII, XIV, and XV in online Data Supplement 1. 1.7. Organization and Integration of Components (Continued) COR LOE New, Revised, or Unchanged Powers et al 2019 Guidelines for Management of AIS e355 2. 