A relationship is considered to be significant if (a) the person receives $10000 or more during any 12-month period, or 5% or more of the person s gross income; or (b) the person owns 5% or more of the voting stock or share of the entity, or owns $10000 or more of the fair market value of the entity. A relationship is considered to be modest if it is less than significant under the preceding definition. *Modest. Significant. Disclosures References 1. Duval X, Delahaye F, Alla F, Tattevin P, Obadia JF, Le Moing V, Doco- Lecompte T, Celard M, Poyart C, Strady C, Chirouze C, Bes M, Cambau E, Iung B, Selton-Suty C, Hoen B; AEPEI Study Group. Temporal trends in infective endocarditis in the context of prophylaxis guideline modifi- cations: three successive population-based surveys. J Am Coll Cardiol. 2012;59:1968 1976. doi: 10.1016/j.jacc.2012.02.029. 2. Correa de Sa DD, Tleyjeh IM,Anavekar NS, Schultz JC, Thomas JM, Lahr BD, Bachuwar A, Pazdernik M, Steckelberg JM, Wilson WR, Baddour LM. Epidemiological trends of infective endocarditis: a population-based study in Olmsted County, Minnesota [published correction appears in Mayo Clin Proc. 2010;85:772]. Mayo Clin Proc. 2010;85:422 426. 3. Federspiel JJ, Stearns SC, Peppercorn AF, Chu VH, Fowler VG Jr. Increasing US rates of endocarditis with Staphylococcus aureus: archinternmed.2011.1027. 4. 