Moderate aortic enlargement and bicuspid aortic valve are associated with aortic dissection in Turner syndrome: report of the International Turner Syndrome Aortic Dissection Registry. Circulation. 2012;126:2220 6. S4.2.4.1-3. Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart di- sease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;129:e521 643. S4.2.4.1-4. Karnis MF, Zimon AE, Lalwani SI, et al. Risk of death in pregnancy achieved through oocyte donation in patients with Turner syn- drome: a national survey. Fertil Steril. 2003;80:498 501. S4.2.4.1-5. Svensson LG, Khitin L. Aortic cross-sectional area/height ratio tim- ing of aortic surgery in asymptomatic patients with Marfan syn- drome. J Thorac Cardiovasc Surg. 2002;123:360 1. S4.2.4.1-6. Svensson LG, Kim K-H, Lytle BW, et al. Relationship of aortic cross-sectional area to height ratio and the risk of aortic dissection in patients with bicuspid aortic valves. J Thorac Cardiovasc Surg. 2003;126:892 3. S4.2.4.1-7. Quezada E, Lapidus J, Shaughnessy R, et al. Aortic dimensions in Turner syndrome. Am J Med Genet A. 2015;167A:2527 32. S4.2.4.2-1. Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart di- sease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;129:e521 643. S4.2.4.2-2. Svensson LG, Adams DH, Bonow RO, et al. Aortic valve and as- cending aorta guidelines for management and quality measures. Ann Thorac Surg. 2013;95:S1 66. S4.2.4.2-3. Hiratzka LF, Creager MA, Isselbacher EM, et al. Surgery for aortic dilatation in patients with bicuspid aortic valves: a statement of clarification from the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2015;133:680 6. S4.2.4.2-4. Michelena HI, Khanna AD, Mahoney D, et al. 