ISBN: 978-1-4731-3093-7 7.1.4 Economic evidence Published literature One health economic study was identified with the relevant comparison and has been included in This is summarised in the health economic evidence profile below (Table 77) and the health economic evidence table in appendix G. See also the health economic study selection flow chart in appendix D. Rehabilitation in chronic heart failure Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: Table 77: Health economic evidence profile: Hospital vs home rehabilitation Study Applicability Limitations Other comments Incremental cost Incremental effects Cost effectiveness Uncertainty [UK] Partially applicable(a) Very serious limitations (b) Comparative costing from UK NHS perspective Population: people with heart failure on optimised medication dosages, clinically stable for one month. Two comparators: 1. Hospital training 2. Home training Follow-up: 5 years 2-1: 480 (c) n/a n/a None. Abbreviations: ICER: incremental cost-effectiveness ratio; QALY: quality-adjusted life years. (a) Does not include any health outcomes. (b) Small sample size, which has significant impact on cost per patient for the home training group. The baseline patient characteristics are not typical with a very high proportion of males. Furthermore, the usual care group nearly 10 years younger than hospital group suggesting there is selection bias. No discounting was undertaken. (c) An additional comparator of usual care was also included in the study. Both hospital training and home training were cost saving compared to usual care. For further detail see full evidence table in appendix G. Chronic Heart Failure Rehabilitation in chronic heart failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: 978-1-4731-3093-7 7.1.5 Evidence statements Clinical Five studies (8 publications) were identified for inclusion within the review. All of the studies compared home-based exercise training with centre-based exercise training supervised by a healthcare professional. 