Application of the 2010 Task Force Criteria to cardiac MRI criteria for diagnosis of arrhythmogenic right ventricular cardiomyopa- thy has improved the specificity of this test.S7.3- Electrocardiographic and Holter findings precede detectable cardiac MRI abnormalities in arrhythmogenic right ventricular cardiomyopa- thy mutation-positive individuals, with only 4% of patients with normal electrocardiographic and Holter results having cardiac MRI abnormalities, Recommendations for Arrhythmogenic Right Ventricular Cardiomyopathy (Continued) COR LOE Recommendations CLINICAL STATEMENTS AND GUIDELINES suggesting that evaluation of cardiac structure and function using cardiac MRI may be unnecessary in mutation-positive individuals who do not have The presence of both electrocardiographic abnormalities and abnor- mal cardiac MRI findings may identify patients at an increased risk for developing sustained Areas of scar identified on cardiac MRI have correlated with the location of VT sub- strate identified by endocardial and epicardial During early stages of disease, a baseline cardiac MRI may provide useful informa- tion along with electrocardiographic and rhythm abnormalities to monitor disease progression over time. Experience and expertise in interpretation of cardiac MRI are important.S7.3-5,S7.3-8 3. Arrhythmogenic right ventricular cardiomy- opathy is characterized by progressive ven- tricular myocyte loss with replacement by fatty or fibrous tissue, and is associated with progressive ventricular dysfunction that may involve both ventricles. 