For adults, the finding of an office BP consistent with hypertension and with SBP/DBP <160/100 mmHg at an initial visit should be confirmed at a follow-up visit within 1 month, based on an average of 2 BP measurements at each visit. 2017 Hypertension Clinical Practice Guidelines Recommendation4 : In adults with an untreated SBP >130 mmHg but <160 mmHg or DBP >80 mmHg but <100 mmHg, it is reasonable to screen for the presence of white-coat hypertension by using either daytime ABPM or HBPM before diagnosis of hypertension.61 68 (Class 2a, Level of Evidence: B-NR) 2017 Hypertension Clinical Practice Guidelines Recommendation4 : In adults with untreated office BPs that are consistently between 120 mmHg and 129 mmHg for SBP or between 75 mmHg and 79 mmHg for DBP, screening for masked hypertension with HBPM (or ABPM) is reasonable.61,62,65,67,161 (Class 2a, Level of Evidence: B-NR) Rationale The evidence for the benefits of screening for HBP is well established. In 2007, the USPSTF reaffirmed its 2003 recommendation to screen for hypertension in adults 18 y of age (Grade A recommendation). Previous evidence reviews commissioned by the USPSTF found good-quality evidence that screening for hypertension has few major harms and provides substantial benefits.162,163 However, these reviews did not address the diagnostic accuracy of different BP measurement protocols or identify a reference standard for measurement confirmation. For the present recommendation, the USPSTF examined the diagnostic accuracy of office BP measurement, ABPM, and HBPM. The USPSTF also assessed the accuracy of these BP measurements and methods in confirming the diagnosis of hypertension. In addition, it reviewed data on optimal screening intervals for diagnosing hypertension in adults. The USPSTF found good evidence that screening for and treatment of HBP has few major harms. 