The KDIGO Co- Chairs appointed the Work Group Co-Chairs, who then assembled the Work Group, to include content experts in adult and pediatric nephrology, blood pressure management, epidemiology, and public health. Cochrane Kidney and Transplant was contracted to conduct systematic evidence review and provide expertise in guideline development methodology. The ERT consisted of adult and pediatric nephrologists, and methodologists with expertise in evidence synthesis, and guideline development. The ERT coordinated the methodological and analytical processes of guideline development, including literature searching, data extraction, critical appraisal, evidence synthesis and meta-analysis, grading the quality of the evidence per outcome, and grading the quality of the evidence for the recommendations. The Work Group was responsible for writing the recommendations and underlying rationale, as well as grading the strength of the recommendation. The KDIGO Co-Chairs, KDIGO Methods Chair, Work Group Co-Chairs, and the ERT had a one-day meeting in Houston, Texas, USA in February 2018 to discuss the previous guideline and the ndings from the KDIGO Controversies Conference on Blood Pressure in Chronic Kidney Disease,374 and nalize the guideline development process. Guideline topics from the previous guideline and new guideline topics were linked with appropriate clinical questions to underpin the systematic evidence review. The draft guideline topics and review topics were nalized with feedback from the Work Group. De ning scope and topics and formulating key clinical questions. The guideline Work Group, with assistance from the ERT, determined the overall scope of the guideline. A preliminary list of topics and key clinical questions was informed by the pre- vious KDIGO guideline141 and the KDIGO Controversies Confer- ence on Blood Pressure in CKD.374 Logical frameworks were developed to present a visual representation of the clinical question and facilitate discussion about the scope of the guideline. 