ISBN: 978-1-4731-3093-7 6.3.1.4 Economic evidence Published literature No relevant health economic studies were identified. See also the health economic study selection flow chart in Appendix D. Unit costs The unit cost of the revascularisation procedures are shown in Table 72 below. The unit cost of all- cause hospitalisation is also provided in Table 73. Table 72: Cost of revascularisation procedures Procedure Code Average cost Source Coronary Artery Bypass Graft (without ventricular reconstruction) Complex Coronary Artery Bypass Graft (CC score 10+) 17,714 NHS reference costs Percutaneous Coronary Intervention Standard Percutaneous Transluminal Coronary Angioplasty (CC score 8-12+) 4,928 (a) NHS reference costs (a) Weighted cost using the activity reported for each of the included HRG codes. Table 73: Unit costs of all-cause hospitalisation Description Unit cost Source All-cause hospitalisation (non-elective) 2,930 NHS Reference costs 2014/15242 6.3.1.5 Evidence statements Clinical Two studies (reported in 14 publications) were identified for inclusion within the review: The evidence compared both an invasive strategy (angiography followed by PCI or CABG at the clinician s discretion) with medical management and CABG (plus medical management) with medical management alone. The evidence for the outcomes from one study (n=1212) comparing CABG (plus medical management) with medical management alone ranged from moderate to very low. This was due to a risk of bias and imprecision as a result of wide confidence intervals around the effect estimate. A single outcome (NYHA class I) was downgraded due to indirectness of the outcome. The outcome reported was the number of people in NYHA class I at the specified follow-up point of 4.7 years rather than the protocol outcome which was improvement in NYHA class. QoL as measured by the EQ-5D, EQ-5D VAS and KCCQ; all-cause hospitalisation and the need for subsequent procedures (CABG and PCI) showed clinically important benefit from CABG (plus medical management). 