All rights reserved. Subject to Notice of rights. ISBN: Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE) Relative effect Anticipated absolute effects Risk with centre-based exercise training Risk difference with home-based exercise training (95% CI) MODERATEa due to risk of bias the home-based exercise training groups was (23.52 lower to 25.16 higher) Exercise Capacity months LOWa due to risk of bias The mean exercise capacity VO2max in the centre-based exercise training groups was The mean exercise capacity VO2max in the home-based exercise training groups was (1.27 lower to 1.46 higher) Exercise capacity 10 metre walk test (fast) HIGH The mean exercise capacity 10 metre walk test (fast) in the intervention group was months VERY LOWa,b due to risk of bias, imprecision (from 55 more to 234 more) Adherence to intervention VERY LOWa,b due to risk of bias, imprecision (from 304 fewer to 288 more) Adherence to intervention VERY LOWa,b due to risk of bias, imprecision (from 94 fewer to 479 more) Adherence to intervention MODERATEa due to risk of bias (from 161 fewer to 134 more) Rehabilitation in chronic heart failure Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE) Relative effect Anticipated absolute effects Risk with centre-based exercise training Risk difference with home-based exercise training (95% CI) Adherence to intervention VERY LOWa,b due to risk of bias, imprecision (from 102 more to 338 more) Adherence to intervention (Hwang MODERATEb due to imprecision f The mean adherence to intervention in the intervention group was (a) Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias. 