Survival implication of left ven- tricular end-systolic diameter in mitral regurgitation due to flail leaflets a long-term follow-up multicenter study. J Am Coll Cardiol. 2009;54:1961 8. 8. Enriquez-Sarano M, Avierinos J-F, Messika-Zeitoun D, et al. Quantitative determinants of the outcome of asymptomatic mitral regurgitation. N Engl J Med. 2005;352:875 83. 9. Crawford MH, Souchek J, Oprian CA, et al. Determinants of survival and left ventricular performance after mitral valve replacement. Department of Veterans Affairs Cooperative Study on Valvular Heart Disease. Circulation. 1990;81:1173 81. 10. Borow KM, Green LH, Mann T, et al. End-systolic volume as a predictor of postoperative left ventricular performance in volume overload from valvu- lar regurgitation. Am J Med. 1980;68:655 63. 11. Suri RM, Clavel M-A, Schaff HV, et al. Effect of recurrent mitral regurgi- tation following degenerative mitral valve repair: long-term analysis of competing outcomes. J Am Coll Cardiol. 2016;67:488 98. 12. Vassileva CM, Mishkel G, McNeely C, et al. Long-term survival of patients undergoing mitral valve repair and replacement: a longitudinal analysis of Medicare fee-for-service beneficiaries. Circulation. 2013;127:1870 6. 13. Suri RM, Vanoverschelde J-L, Grigioni F, et al. Association between early surgical intervention vs watchful waiting and outcomes for mitral regurgi- tation due to flail mitral valve leaflets. JAMA. 2013;310:609 16. 14. Grigioni F, Tribouilloy C, Avierinos JF, et al. Outcomes in mitral regurgita- tion due to flail leaflets a multicenter European study. JACC Cardiovasc Imaging. 2008;1:133 41. 15. Lazam S, Vanoverschelde J-L, Tribouilloy C, et al. Twenty-year outcome af- ter mitral repair versus replacement for severe degenerative mitral regur- gitation: analysis of a large, prospective, multicenter, international registry. Circulation. 2017;135:410 22. 16. Tribouilloy C, Rusinaru D, Szymanski C, et al. 