For example, those at high-risk will likely benefit from an early invasive strategy (within 12 to 24 h), while intermediate-risk patients may receive delayed invasive strategy (within 24 to 72 h). In addition, risk scores, such as the TIMI risk index and GRACE risk model are useful in predicting recurrent cardiovascular outcomes (short- and intermediate-term) following NSTEMI.11,161,162 Clinical Recommendation(s) 2014 AHA/ACC Guideline for the Management of Patients With Non ST-Elevation Acute Coronary Syndromes11 1. Risk scores should be used to assess prognosis in patients with NSTE-ACS.161,163 170 (Class I, Level of Evidence: A) ACC indicates American College of Cardiology; AHA, American Heart Association; GRACE, Global Registry of Acute Coronary Events; NSTE-ACS, non ST-elevation acute coronary syndrome; NSTEMI, non ST-elevation myocardial infarction; and TIMI, Thrombolysis in Myocardial Infarction. Appendix A. Continued 35 Short Title: QM-2: Early Invasive Strategy for High-Risk NSTEMI QM-2: Acute NSTEMI: Early Invasive Strategy (Within <24 Hours) for High-Risk NSTEMI Patients Measure Description: Percentage of patients, age 18 y, hospitalized with acute NSTEMI, who are at high risk and who receive an early invasive strategy within 24 h of admission. Numerator Patients with acute NSTEMI who are high risk* and receive early invasive strategy (diagnostic angiography with intent to perform revascularization if appropriate based on coronary anatomy) within 24 h of admission *A high-risk NSTEMI patient is best defined by an objective risk score (eg, GRACE risk score >140 or TIMI risk score >4). 