One study compared a moderate salt intake (2300mg/day sodium) with low salt intake (1500mg/day sodium) in people with HF and normal serum sodium. A further study compared an education programme with support to maintain fluid restriction at 1.5-2L (intervention) with general support unrelated to the fluid restriction (control) in people with HF who were already in a trial of an intrathoracic impedance monitoring device who had been hospitalised in the last six months. Table 29: Summary of studies included in the review Study Intervention and comparison Population Outcomes Comments Colin- Ramirez (n=19) Salt restriction programme with target of reducing salt to <1500mg/day (n=19) Salt restriction programme with target of reducing salt to <2300mg/day Adults with HFREF or HFPEF on optimally tolerated medical therapy with normal serum sodium Age median 66 Quality of Life (KCCQ) six months Renal failure (Creatinine) six months Actual intake of salt in two groups (median): All results reported using non-parametric summary scores. Significant inequality at Chronic Heart Failure Treating Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: 978-1-4731-3093-7 Study Intervention and comparison Population Outcomes Comments ethnicity baseline. BMI and oedema inadequately reported for extraction. Normal sodium status Pilot study. Reilly Fluid restriction with self-care programme to encourage fluid restriction to 1.5-2L Attention control received same fluid prescription and contacts, but interaction more general Both groups also encouraged to restrict salt to Adults with HF enrolled in a different trial. NYHA class II-IV Had previously been prescribed fluid regimen of Age mean 63 African American EQ5D visual analogue scale (VAS) six months Oedema three months (extracted, but not analysed) Actual fluid intake of two groups: intervention mean 1703, control No baseline sodium levels given. Pilot study. Treating Heart Failure Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. 