Therefore, the committee made a recommendation based on their knowledge and experience. The committee agreed that early mobilisation may be appropriate in some cases where people need minimal assistance to mobilise, such as in those who have suffered a mild stroke, or are experiencing language and/or upper limb dysfunction alone. Regarding the recommendation not to offer high-intensity mobilisation within the first 24 hours of symptom onset, a published within-trial cost-effectiveness analysis from the Australian hospital perspective was identified. However, the treatment effect for the health outcome mRS 0 to 2 used in the study differed from the treatment effect calculated in the clinical review. Because the cost-effectiveness evidence was incompatible with the results of the clinical review, the committee chose to make a recommendation based on the clinical evidence for mortality. The evidence suggested clinical harm associated with high- intensity mobilisation within the first 24 hours after acute stroke. However, based on their clinical experience they discussed that this harm was most relevant to those who need help to sit out of bed, stand or walk. Therefore, they limited the recommendation to this group because they did not want to prevent appropriate early mobilisation in people who are independently mobile after having a stroke. How the recommendations might affect practice The committee was confident that making these recommendations would not have a resource impact, because there was no indication that mobilising later and with a lower 2022 intensity leads to a longer length of stay. The committee noted that people will still be assessed and mobilised and there are unlikely to be differences in staff costs. In current practice, mobilisation strategies differ according to stroke severity and the clinical condition of the person with stroke. The strategy may also be impacted by the availability of different types of specialist seating. 