2015;187:66 74. S5.1.5.2-7. Bunch TJ, Mahapatra S, Murdock D, et al. Ranolazine reduces ventricular tachycardia burden and ICD shocks in patients with drug-refractory ICD shocks. Pacing Clin Electrophysiol. 2011;34:1600 6. S5.1.5.2-8. Scirica BM, Braunwald E, Belardinelli L, et al. Relationship between nonsustained ventricular tachycardia after non-ST-elevation acute coronary syndrome and sudden cardiac death: observations from the metabolic efficiency with ranolazine for less ischemia in non- ST-elevation acute coronary syndrome-thrombolysis in myocar- dial infarction 36 (MERLIN-TIMI 36) randomized controlled trial. Circulation. 2010;122:455 62. S5.1.5.2-9. Zareba W, Daubert JP, Beck CA, et al. Ranolazine in High-Risk ICD Patients (RAID) Trial. Presented at: Heart Rhythm Society Annual Scientific Sessions. 2017; LBCT02 01. S5.1.5.2-10. Reiter MJ, Reiffel JA, Importance of beta blockade in the therapy of serious ventricular arrhythmias. Am J Cardiol. 1998;82:9I 19I. S5.1.5.2-11. Ellison KE, Hafley GE, Hickey K, et al. Effect of beta-blocking ther- apy on outcome in the Multicenter UnSustained Tachycardia Trial (MUSTT). Circulation. 2002;106:2694 9. S5.1.5.2-12. Reiken S, Wehrens XH, Vest JA, et al. Beta-blockers restore cal- cium release channel function and improve cardiac muscle perfor- mance in human heart failure. Circulation. 2003;107:2459 66. S5.1.5.2-13. MERIT-HF Group Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet. 1999;353:2001 7. S5.1.5.2-14. Packer M, Bristow MR, Cohn JN, et al. The effect of carvedilol on morbidity and mortality in patients with chronic heart fail- ure. US Carvedilol Heart Failure Study Group. N Engl J Med. 1996;334:1349 55. S5.1.5.2-15. Committees of the Cardiac insufficiency Bisoprolol Study II. The cardiac insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial. Lancet. 1999;353:9 13. S5.1.5.2-16. A randomized trial of propranolol in patients with acute myocar- dial infarction. Mortality results. JAMA. 1982;247:1707 14. S5.1.5.2-17. Kontos MC, Diercks DB, Ho PM, et al. 