OR (secondary ADJ prevention).ti,ab. OR (primary ADJ prevention).ti,ab. OR angina.ti,ab. #6 Limit to RCTs/SRs/ Meta-analysis Randomized controlled trials/systematic review/meta-analysis hedge [see Search Limits at the end of this table] #7 Limit to additional study designs exp cohort studies/ OR exp longitudinal studies/ OR exp retrospective studies/ OR exp prospective studies OR exp controlled study/ or exp clinical trial/ or exp comparative study/ OR major clinical study/ OR cross-over studies/ or crossover procedure/ or cross over studies/ OR observational study/ OR validation studies/ OR exp case-control studies/ OR follow-up studies/ #9 Apply limits See Search Limits at the end of the table Question Set # Concept Strategy Question Stability of lipid levels over time #1 Dyslipidemia exp dyslipidemias/ OR exp cholesterol/ OR lipids/ OR (dyslipidemia* OR dyslipidaemia* OR dyslipidproteinemia* OR dyslipidproteinaemia* OR hyperlipidemia* OR hyperlipidaemia* OR hypercholesterolemia* OR hypercholesterolaemia* OR hyperlipoproteinemia* OR hyperlipoproteinaemia* OR hypertriglyceridemia* OR hypertriglyceridaemia* OR hyperlipemia OR hyperlipaemia OR cholesteryl* OR cholesterol* OR lipid* OR lipoprotein* OR tryglycer* OR triaclyglycer* OR "HDL-C" OR "LDL-C" OR "HDL C" OR "LDL C").ti,ab. #2 CVD exp *Cardiovascular Diseases/pc or cardiovascular diseases/ or heart diseases/ or vascular diseases/ or exp arterial occlusive diseases/ or cerebrovascular disorders/ or exp brain ischemia/ or exp stroke/ or exp myocardial ischemia/ or exp myocardial Infarction/ or exp heart arrest/ or exp hypertension/ or exp peripheral vascular diseases/ or ((heart* or cardio* or cardiac* or coronary or vascular or cerebrovascular or artery or arteries) ADJ5 (disease* or syndrome* or event* or ischem* or ischaem* or plaque*)).ti,ab. or (hyperten* or atherosclero* or arteriosclero* or angina or (Heart ADJ attack*) or (myocardial ADJ infarct*) or stroke* or (cerebrovascular ADJ accident*)).ti,ab. 