Physiological criteria, such as an assessment of fractional flow reserve (FFR), has been used in deciding when revascularization is indicated. Thus, for recommenda- tions about revascularization in this section, coronary steno- ses with FFR 0.80 can also be considered to be As noted, the revascularization recommendations have been formulated to address issues related to 1) improved survival and/or 2) improved symptoms. When one method of revascularization is preferred over the other for improved survival, this consideration, in general, takes precedence over improved symptoms. When discussing options for revascu- larization with the patient, he or she should understand when the procedure is being performed in an attempt to improve symptoms, survival, or both. Although some results from the SYNTAX (Synergy be- tween Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery) study are best characterized as subgroup analyses and hypothesis generating, SYNTAX nonetheless represents the latest and most comprehensive comparison of PCI and CABG.13,14 Therefore, the results of SYNTAX have been considered appropriately when formulating our revas- cularization recommendations. Although the limitations of using the SYNTAX score for certain revascularization rec- ommendations are recognized, the SYNTAX score is a reasonable surrogate for the extent of CAD and its complex- ity and serves as important information that should be considered when making revascularization decisions. Recom- mendations that refer to SYNTAX scores use them as surrogates for the extent and complexity of CAD. Revascularization recommendations to improve survival and symptoms are provided in the following text and are summarized in Tables 2 and 3. References to studies com- paring revascularization with medical therapy are presented when available for each anatomic subgroup. See Online Data Supplements 1 and 2 for additional data regarding the survival and symptomatic benefits with CABG or PCI for different anatomic subsets. 2.1. 