Atenolol, angiotensin receptor blockers, and direct renin inhibitors are contraindicated in pregnancy and should not be used (Class III; Level of Evidence C). 4. After giving birth, women with chronic hypertension should be continued on their antihypertensive regi- men, with dosage adjustments to reflect the decrease in volume of distribution and glomerular filtration rate that occurs after delivery. They should also be monitored carefully for the development of postpar- tum preeclampsia (Class IIa; Level of Evidence C). Prevention of Stroke in Women With a History of Preeclampsia 1. Because of the increased risk of future hypertension and stroke 1 to 30 years after delivery in women with a history of preeclampsia (Level of Evidence B), it is reasonable to (1) consider evaluating all women start- ing 6 months to 1 year post partum, as well as those who are past childbearing age, for a history of pre- eclampsia/eclampsia and document their history of preeclampsia/eclampsia as a risk factor, and (2) eval- uate and treat for cardiovascular risk factors includ- ing hypertension, obesity, smoking, and dyslipidemia (Class IIa; Level of Evidence C). Cerebral Venous Thrombosis Cerebral venous thrombosis (CVT) is a stroke type that is caused by thrombus formation in 1 of the venous sinuses and manifests primarily as headache. CVT makes up 0.5% to 1% of all strokes but is the stroke type that shows the most prominent differential sex prevalence.191,192 In adulthood, the majority of affected individuals are women, who represent >70% of cases in most studies193 200 (Table 7). The overall adult incidence of and is higher in women (1.86 per 100000; 95% CI, 1.44 2.36) This sex difference is even more notable in women aged 31 to 50 years, in whom the incidence may be as high as 2.78 per 100000 person-years (95% CI, 1.98 3.82). 