16 month follow up (mortality, all- cause hospitalisation, quality of life). Pulignano [Italy] Partially applicable (c) Potentially serious limitations (d) Cost-effectiveness analysis (health outcomes: death or readmission for heart failure and all-cause admission rate) Within-trial analysis of a RCT Population: people over the age of 70 with heart failure with reduced and normal ejection fraction, discharged home after a hospitalisation. Interventions: 1. Usual care (primary/ secondary care) 2. Multidisciplinary team saving of See clinical review of Del Int 2 saves death and/or heart failure- related admission avoided. Int 2 saves 2,155 per all- cause admission avoided. None undertaken. Referral and approach to care Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: Study Applicability Limitations Other comments Incremental cost Incremental effects Cost- effectiveness Uncertainty consisting of a cardiologist, experienced in geriatrics (case managers), two to four specialised nurses, and the patient s primary care physician. 2 year follow up Abbreviations: QALY: quality-adjusted life years; RCT: randomised controlled trial (a) Spanish resource use data and unit costs (year not reported, assumed to be 2004) may not reflect current NHS context. QALYs were not used as the health outcome measure (b) Within-trial analysis and so does not reflect the full body of available evidence available for this intervention. Atienza is 1 of 5 studies included comparing MDT clinic to usual care in high risk patients. No exploration of uncertainty. (c) Italian national health service resource use and unit costs may not reflect current UK NHS context. QALY data was not reported clearly enough to report and therefore were not used as the health outcome measure. Discounting was not applied. (d) Within-trial analysis and therefore does not reflect the full body of evidence available for this comparison. 