Methodology and Evidence Review Clinical trials presented at the major cardiology organi- zations 2013 to 2015 annual scienti c meetings and other selected reports published in a peer-reviewed format through August 2015 were reviewed by the 2011 PCI and 2013 STEMI GWCs and the Task Force to identify trials and other key data that might affect guideline rec- ommendations. The information considered important enough to prompt updated recommendations is included in evidence tables in the Online Data Supplement. J A C C V O L . 6 7 , N O . 1 0 , 2 0 1 6 Levine et al. Consult the full-text versions of the 2011 PCI and 2013 STEMI guidelines (9,10) for recommendations in clinical areas not addressed in the focused update. The individual recommendations in this focused update will be incor- porated into future revisions or updates of the full-text guidelines. 1.2. Organization of the GWC For this focused update, representative members of the 2011 PCI and 2013 STEMI GWCs were invited to partic- ipate. Members were required to disclose all RWI relevant to the topics under consideration. The entire membership of both GWCs voted on the revised recommendations and text. The latter group was composed of experts represent- ing cardiovascular medicine, interventional cardiology, electrophysiology, heart failure, cardiac surgery, emer- gency medicine, internal medicine, cardiac rehabilitation, nursing, and pharmacy. The GWC included representatives from the ACC, AHA, American College of Physicians, American College of Emergency Physicians, and Society for Cardiovascular Angiography and Interventions (SCAI). 1.3. Review and Approval This document was reviewed predominantly by the prior reviewers from the respective 2011 and 2013 guidelines. These included 8 of cial reviewers jointly nominated by the ACC and AHA, 4 of cial/organizational reviewers nominated by SCAI, and 25 individual content reviewers. 