Many, but not all, studiesS4.4-4,S4.4-6,S4.4-8,S4.4-25,S4.4-26 have identified a minimal increase in risk of CVD complications or all-cause mortality in patients who have white coat hyperten- sion. This has resulted in a recommendation by some panels to screen for white coat hypertension with ABPM (or HBPM) to avoid initiating antihypertensive drug treatment in such The white coat effect and masked uncontrolled hypertension appear to follow the risk profiles of their white coat hypertension and masked hypertension coun- There are no data on the risks and benefits of treating white coat and masked hypertension. Despite these method- ological differences, the data are consistent in indicating that Table 12. BP Patterns Based on Office and Out-of-Office Measurements Office/Clinic/ Healthcare Setting Home/Nonhealthcare/ ABPM Setting Normotensive No hypertension No hypertension Sustained hypertension Hypertension Hypertension Masked hypertension No hypertension Hypertension White coat hypertension Hypertension No hypertension ABPM indicates ambulatory blood pressure monitoring; and BP, blood pressure. Whelton et al 2017 High Blood Pressure Clinical Practice Guideline e27 masked hypertension and masked uncontrolled hypertension are associated with an increased prevalence of target organ damage and risk of CVD, stroke, and mortality compared with normotensive individuals and those with white coat hypertension. Figure 1 is an algorithm on the detection of white coat hypertension or masked hypertension in patients not on drug therapy. Figure 2 is an algorithm on detection of white coat effect or masked uncontrolled hypertension in patients on drug therapy. Table 12 is a summary of BP patterns based on office and out-of-office measurements. Recommendation-Specific Supportive Text 1. White coat hypertension prevalence averages approxi- mately 13% and as high as 35% in some hypertensive and ABPM and HBPM are better predictors of CVD risk due to elevated BP than are of- fice BP measurements, with ABPM being the preferred measurement option. 