Review criteria were not suggested because implementation with prioritization and development of review criteria have to proceed locally. Furthermore, most recommendations are discretionary, requiring substantial discussion among stakeholders before they can be adopted as review criteria. Suggested audit criteria were provided to assess impact of guideline after publication. Research recommendations were also outlined to address current gaps in the evidence base. Abbreviations: CKD, chronic kidney disease; CPG, clinical practice guideline; CVD, cardiovascular disease; GRADE, Grading of Recommendations Assessment, Development and Evaluation; HDL-C, high-density lipoprotein cholesterol; KDIGO, Kidney Disease: Improving Global Outcomes; LDC-C, low-density lipoprotein cholesterol; RCT, randomized controlled trial; TC, total cholesterol; TG, triglyceride. methods for guideline development the only database searched. Hand searches of journals were not performed, and review articles and textbook chapters were not systematically searched. However, any important studies known to domain experts that were missed by the electronic literature searches were added to retrieved articles and reviewed by the Work Group. Review of Guideline Development Process Several tools and checklists have been developed to assess the quality of the methodological process for systematic review and guideline development. These include the Appraisal of Guidelines for Research and Evaluation (AGREE 2) the Conference on Guideline Standardization and the Institute of Medicine s recent Standards for Systematic Reviews113 and Clinical Practice Guidelines We Can Trust.114 Table 16 and Supplemental Appendix 2 online show, respectively, the criteria which correspond to the COGS checklist and the Institute of Medicine standards, and how each one of them is addressed in this guideline. SUPPLEMENTARY MATERIAL Supplemental Appendix 1: Online search strategies. Supplemental Appendix 2: Concurrence with Institute of Medicine standards for systematic reviews and for guidelines. 