Based on the clinical evidence reviewed, the committee agreed that home- and centre-based forms of cardiac rehabilitation seem to be similarly effective for patients with heart failure. The committee noted that the body of evidence was small (5 trials of 335 patients) and the majority of outcomes were at high risk of bias. The patient populations included in the trials were also much younger than the typical heart failure patients Chronic Heart Failure Rehabilitation in chronic heart failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: 978-1-4731-3093-7 in the UK. However, the committee agreed that this was common in rehabilitation trials and wasn t specific to home versus centre-based trials. The committee acknowledged that the findings of this review which suggested that no clear difference could be demonstrated between home- and centre-based programmes. The committee also noted that findings in younger populations might also not translate to more typical older patient populations. The committee was also conscious that the critical outcome of hospitalisation was not reported by any of the included studies. The evidence on patient completion suggested a clinically important increase in completion rates in the home-based groups compared to the centre-based groups. For some patients, the burden of travelling to a centre for rehabilitation and/or dislike of exercising in a group setting may be a substantial barrier to participation in centre-based programmes. For these patients, home-based rehabilitation may be a more attractive and achievable option. Similarly, a patient representative expressed his view that the main concern of many younger patients with heart failure is to learn and understand their limits with professional supervision, to enable them to then exercise safely and comfortably alone. 