Compression Stocking to Prevent PTS Summary of the Evidence AT9 suggested routine use of graduated compression stockings for 2 years after DVT to reduce the risk of PTS. Thatrecommendationwasmainlybased on ndingsoftwo small, single-center, randomized trials in which patients and study personnel were not blinded to stocking use (no The quality of the evidence was moderate because of risk of bias resulting from a lack of blinding of an outcome (PTS) that has a large subjective component and because of serious imprecision of the combined ndings of the two trials (Table 17, e-Table 17). Since AT9, a much larger multicenter, placebo-controlled trial at low risk of bias found that routine use of graduated compression stockings did not reduce PTS or have other Based on this trial, we now suggest that graduated compression stockings not be used routinely to prevent PTS and consider the quality to the evidence to be moderate (Table 17, e-Table 17). The same study found that routine use of graduated compression stockings did not reduce leg pain during the 3 months after DVT diagnosis (Table 17, e-Tables 2 This nding, however, does not mean that graduated compression stockings will not reduce acute symptoms of DVT or chronic symptoms in those who have developed PTS. *18. In patients with acute DVT of the leg, we sug- gest not using compression stockings routinely to prevent PTS (Grade 2B). Remarks: This recommendation focuses on prevention of the chronic complication of PTS and not on the treatment of symptoms. For patients with acute or chronic symptoms, a trial of graduated compression stockings is often justi ed. Whether to Treat Subsegmental PE Summary of the Evidence Subsegmental PE refers to PE that is con ned to the subsegmental pulmonary arteries. 