OVERVIEW OF PROCESS The development process for the KDIGO Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease included the following steps: K Appointing Work Group members and the ERT. K Discussing process, methods, and results. K Developing and refining topics. K Identifying populations, interventions or predictors, and outcomes of interest. K Selecting topics for systematic evidence review. K Standardizing quality assessment methodology. K Developing and implementing literature-search strategies. K Screening abstracts and retrieving full-text articles on the basis of pre-defined eligibility criteria. K Creating data extraction forms. K Extracting data and performing critical appraisal of the literature. K Grading the methodology and outcomes in individual studies. K Tabulating data from individual studies into summary tables. K Grading quality of evidence for each outcome across studies, and assessing the overall quality of evidence across outcomes with the aid of evidence profiles. K Grading the strength of recommendations on the basis of the quality of evidence and other considerations. K Finalizing guideline recommendations and supporting rationales. K Sending the guideline draft for peer review to the KDIGO Board of Directors in December 2010 and for public review in July 2011. K Publishing the final version of the guideline. The Work Group, KDIGO Co-Chairs, ERT, and KDIGO support staff met for three 2-day meetings for training in the guideline development process, topic discussion, and consensus development. Commissioning of Work Group and ERT The KDIGO Co-Chairs appointed the Work Group Co- Chairs, who then assembled the Work Group of domain experts, including individuals with expertise in internal medicine, adult and pediatric nephrology, cardiology, hypertension, pharmacology, epidemiology, and endocrinol- ogy. 