Long-term renal and cardiovascular outcomes in Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack trial (ALLHAT) participants by baseline estimated GFR. Clin J Am Soc Nephrol. Jun 2012;7(6):989-1002. PMID: 22490878. 142. Thomopoulos C, Parati G, Zanchetti A. Effects of blood pressure-lowering treatment on cardiovascular outcomes and mortality: 14 - effects of different classes of antihypertensive drugs in older and younger patients: Overview and meta-analysis. J Hypertens. Aug 2018;36(8):1637-1647. PMID: 29847487. 143. Beckett NS, Peters R, Fletcher AE, et al. Treatment of hypertension in patients 80 years of age or older. N Engl J Med. 2008;358(18):1887-1898. PMID: 18378519. 144. Jamerson K, Weber MA, Bakris GL, et al. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med. Dec 4 2008;359(23):2417-2428. PMID: 19052124. 145. Fried LF, Emanuele N, Zhang JH, et al. Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med. Nov 14 2013;369(20):1892-1903. PMID: 24206457. 146. Parving HH, Brenner BM, McMurray JJ, et al. Cardiorenal end points in a trial of aliskiren for type 2 diabetes. N Engl J Med. Dec 6 2012;367(23):2204-2213. PMID: 23121378. 147. Yusuf S, Teo KK, Pogue J, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med. Apr 10 2008;358(15):1547-1559. PMID: 18378520. 148. Cushman WC, Ford CE, Einhorn PT, et al. Blood pressure control by drug group in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack trial (ALLHAT). J Clin Hypertens (Greenwich). Oct 2008; 10(10):751-760. PMID: 19090876. 149. Salam A, Kanukula R, Atkins E, et al. Efficacy and safety of dual combination therapy of blood pressure- lowering drugs as initial treatment for hypertension: A systematic review and meta-analysis of randomized controlled trials. J Hypertens. Sep 2019;37(9):1768-1774. PMID: 30986788. 150. Liu L, Xu B, Ju Y. 