Although some results from the SYNTAX (Synergy be- tween Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery) study are best characterized as subgroup analyses and hypothesis generating, SYNTAX nonetheless represents the latest and most comprehensive comparison of PCI and CABG.949,950 Therefore, the results of SYNTAX have been considered appropriately when formulating our revascularization recommendations. Although the limitations of using the SYNTAX score for certain revascularization recommendations are recognized, the SYNTAX score is a reasonable surrogate for the extent of CAD and its complex- ity and serves as important information that should be considered when making revascularization decisions. Recom- mendations that refer to SYNTAX scores use them as surrogates for the extent and complexity of CAD. Revascularization recommendations to improve survival and symptoms are provided in the following text and are summarized in Tables 18 and 19. References to studies comparing revascularization with medical therapy are pre- sented when available for each anatomic subgroup. When such studies have been completed only for CABG, RCTs or cohort studies comparing CABG with PCI are presented, but the LOE for PCI is downgraded. See Online Data Supplements 3 and 4 for additional data regarding the survival and symptomatic benefits with CABG or PCI for different anatomic subsets. 5.1. Heart Team Approach to Revascularization Decisions: Recommendations Class I 1. A Heart Team approach to revascularization is recommended in patients with unprotected left main or complex CAD.950 952 (Level of Evidence: C) Fihn et al Stable Ischemic Heart Disease: Full Text e413 Table 18. 