However, the ERT conducted searches for systematic reviews of cost-effectiveness studies in support of selected topics, such as BP measurement techniques. Practice points In addition to graded recommendations, KDIGO guidelines now include practice points to help clinicians better evaluate and implement the guidance from the expert Work Group. Practice points are consensus statements about a speci c aspect of care, and they supplement recommendations for which a larger quantity of evidence was identi ed. These were used when no formal systematic evidence review was undertaken, or there was insuf cient evidence to provide a graded recommendation. Practice points represent the expert judg- ment of the guideline Work Group, but they also may be based on limited evidence. Practice points were sometimes formatted as a table, a gure, or an algorithm to make them easier to use in clinical practice. Format for guideline recommendations Each guideline recommendation provides an assessment of the strength of the recommendation (strong, level 1 or weak, level 2) and the quality of evidence (A, B, C, D). The recommendation state- ments are followed by a short remark, Key information (Balance of bene ts and harms, Quality of evidence, Values and preferences, Resource use and costs, Considerations for implementation), and a rationale. Each recommendation is linked to relevant SoF tables. An underlying rationale supported each practice point. Limitations of the guideline development process The evidence review prioritized RCTs as the primary source of evi- dence. For a select number of clinical questions in this guideline, the ERT undertook a comprehensive evidence review beyond RCTs. However, these reviews were not exhaustive, as specialty or regional databases were not searched, and manual searching of journals was not performed for these reviews. 