HIGH The mean change in quality of life in the control groups was The mean quality of life in the intervention groups was Quality of life EQ5D VAS. Scale from: 0 to 100. months LOWa, b due to risk of bias, imprecision The mean change in quality of life in the control groups was The mean quality of life in the intervention groups was Quality of life KCCQ. Scale from: 0 to 100. months LOWa, b due to risk of bias, imprecision The mean change in quality of life in the control groups was The mean quality of life in the intervention groups was Quality of life MLWHFQ . Scale from: 0 to 105. HIGH The mean quality of life in the control groups was The mean quality of life in the intervention groups was Treating Heart Failure Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE) Relative effect Anticipated absolute effects Risk with Placebo Risk difference with Intravenous iron (95% CI) Improvement in NYHA class Data on improvement in NYHA has only been extracted where quality of life data is not reported in a trial. 