Am Indian indicates American Indian; Non-Hisp, non-Hispanic; and PI, Pacific Islander. Bushnell et al Guidelines for Prevention of Stroke in Women 1551 also reported, together with a 17% reduction in cardiovascu- lar mortality (95% CI, 3% 29%).108 Therefore, women benefit significantly from these interventions, as do men, and the type of medication used to lower the BP may be less relevant than the achievement of target BP goals. Analyses of women of different racial/ethnic and age groups have suggested particular benefit of BP reduction in younger and black women. In 1 large systematic review of prospective studies, BP treatment in those aged 30 to 54 years (of whom 79% were white) yielded a reduction in risk of fatal and nonfa- tal cerebrovascular events of 41% (95% CI, 8% 63%), as well as a 27% reduction in fatal and nonfatal cardiovascular events In this same study, when black women were considered as a separate group, BP treatment reduced the risk of fatal and nonfatal cerebrovascular events by 53% Sex, BP, Antihypertensive Treatment, and Achieving BP Goals Numerous studies have shown that females have lower BP levels over much of their life span than their age-matched but this changes with age. 