Home- based disease management program to improve psychological status in patients with heart failure in Japan. Circulation Journal. 2013; 77(4):926-33 342. Tsuchihashi-Makaya M, Matsuo H, Kakinoki S, Takechi S, Tsutsui H. Rationale and design of the Japanese Heart Failure Outpatients Disease Management and Cardiac Evaluation (J- HOMECARE). Journal of Cardiology. 2011; 58(2):165-172 343. Tsutsui H, Ito H, Kitakaze M, Komuro I, Murohara T, Izumi T et al. Double-Blind, Randomized, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Eplerenone in Japanese Patients With Chronic Heart Failure (J-EMPHASIS-HF). Circulation Journal. 2017; 82(1):148- 344. Tsuyuki RT, Fradette M, Johnson JA, Bungard TJ, Eurich DT, Ashton T et al. A multicenter disease management program for hospitalized patients with heart failure. Journal of Cardiac 345. Udelson JE, Feldman AM, Greenberg B, Pitt B, Mukherjee R, Solomon HA et al. Randomized, double-blind, multicenter, placebo-controlled study evaluating the effect of aldosterone antagonism with eplerenone on ventricular remodeling in patients with mild-to-moderate heart failure and left ventricular systolic dysfunction. Circulation: Heart Failure. 2010; 346. University of Alberta. The long term effects of dietary sodium restriction on clinical outcomes in patients with heart failure [NCT02012179]. 2016. Available from: https://clinicaltrials.gov/ct2/show/NCT02012179 Last accessed: 06/12/16. 347. Van Houwelingen HC, Arends LR, Stijnen T. Advanced methods in meta-analysis: multivariate approach and meta-regression. Statistics in Medicine. 2002; 21(4):589-624 348. Van Houwelingen HC, Zwinderman KH, Stijnen T. A bivariate approach to meta-analysis. Statistics in Medicine. 1993; 12(24):2273-2284 349. van Veldhuisen DJ, Aass H, El Allaf D, Dunselman PH, Gullestad L, Halinen M et al. Presence and development of atrial fibrillation in chronic heart failure. Experiences from the MERIT-HF Study. European Journal of Heart Failure. 2006; 8(5):539-46 350. Vardeny O, Claggett B, Anand I, Rossignol P, Desai AS, Zannad F et al. 