(2D) 6.3: We suggest that an ARB or ACE-I be used in children with CKD ND in whom treatment with BP-lowering drugs is indicated, irrespective of the level of proteinuria. (2D) Chapter 7: Blood pressure management in elderly persons with CKD ND 7.1: Tailor BP treatment regimens in elderly patients with CKD ND by carefully considering age, co-morbidities and other therapies, with gradual escalation of treatment and close attention to adverse events related to BP treatment, including electrolyte disorders, acute deterioration in kidney function, orthostatic hypotension and drug side effects. (Not Graded) summary of recommendation statements Chapter 1: Introduction There is a strong association between chronic kidney disease (CKD) and an elevated blood pressure (BP) whereby each can cause or aggravate the other. BP control is fundamental to the care of patients with CKD and is relevant at all stages of CKD regardless of the underlying cause. Clinical practice guidelines (CPGs) have been published on this topic by many authoritative bodies over the past decade, the most comprehensive being the National Kidney Foundation s (NKF) Kidney Disease Outcomes Quality Initiative (KDOQI) Clinical Practice Guidelines on Hypertension and Antihyper- tensive Agents in Chronic Kidney Disease, which was based on evidence collected up to 2001 (http://www.kidney.org/ The Kid- ney Disease: Improving Global Outcomes (KDIGO) Board believed that it would be clinically useful to update this CPG to incorporate the evidence gathered since then. KDIGO therefore commissioned an evidence review to include the recent literature and assembled a Work Group with the mandate of writing an updated guideline relevant to an international audience. This KDIGO Guideline, entitled Management of Blood Pressure in Chronic Kidney Disease, is the result of these efforts. 