The frequency of composite events (neurological deterioration, vascular events, and death) at 1 month was significantly lower in patients treated with antithrombotics compared with those who were not (1.6% versus 11.1%; P=0.041). Neither antiplatelet (n=72) nor anticoagulant (n=28) treatment after HT was associated with enlargement of the original HT or development of new HT or neurological deterioration.382 Individual assessment of the clinical indication, benefits, and associated risks is warranted.10,382,383 See Table LI in online Data Supplement 1. 6.7. Carotid Revascularization 6.7. Carotid Revascularization COR LOE New, Revised, or Unchanged When revascularization is indicated for secondary prevention in patients with minor, nondisabling stroke (mRS score 0 2), it is reasonable to perform the procedure between 48 hours and 7 days of the index event rather than delay treatment if there are no contraindications to early revascularization. IIa B-NR Recommendation revised from 2014 Secondary Prevention. The risk of recurrent stroke resulting from symptomatic carotid stenosis is highest in the first few days after the initial Although there is evidence that early or emergency revascularization via either CEA or carotid angioplasty and stenting may be safe in selected cases,330 332 there are no high-quality prospective data supporting early versus late carotid revascularization in all cases.333 In cases of minor, nondisabling stroke, a meta-analysis by De Rango et demonstrates favorable rates of complications when treated at least 48 hours after the initial event, and the risks are not different when treated between 0 to 7 and 0 to 15 days. Revascularization between 48 hours and 7 days after initial stroke is supported by these data in cases of nondisabling stroke (mRS score 0 2).334 See Table LXXVIII in online Data Supplement 1. 6.8. Treatment of Hyperlipidemia 6.8.1. 