Nonetheless, multiple smaller interven- tional trials and observational studies with multiple mean- ingful outcomes for children have consistently shown bene ts of BP lowering. For example, observational data from CKiD, published in abstract form, suggest that MAP targets at <90th percentile are bene cial for children with either glomerular or non-glomerular causes of CKD, and lower MAP at <50th percentile may have an additional bene t.366 Therefore, a range of MAP targets, including the 50th 90th percentile, may also be considered. Values and preferences. The Work Group judged that the prevention of kidney failure and progressive kidney function loss would be of high value to nearly all well-informed patients or caregivers. Published patient-reported outcome data from the SONG Kids study reported that children with kidney disease and caregivers rated kidney function as an important outcome, whereas BP control was also rated as an important outcome by caregivers.367 In the judgment of the Work Group, most patients would value these clinical bene ts despite the inconvenience and potential risk of harms associated with aggressive BP management (e.g., multiple medications, more-frequent dosing, possible adverse events if dehydrated, and the burden of monitoring with 24-hour ABPM). Patients for whom medication burden or the burden of ABPM monitoring are particularly important concerns may be more inclined not to follow this recommendation. Resource use and costs. In the judgment of the Work Group, the potential bene ts associated with ABPM outweigh the costs and inconvenience associated with its implementa- tion. Patients and families in areas where ABPM is unavailable or less affordable will be less inclined to follow this recom- mendation and may choose to use clinic-based auscultatory BP monitoring instead. Consideration for implementation. 