(b) Downgraded for indirectness as not protocol outcome of count rates for hospitalisations. (c) Downgraded one increment as confidence interval crosses one MID or two increments as confidence interval crosses two MID. (d) Used estimated control rate. 9.2.3.1.9 High risk, Long, Home-based MDT Table 112: Clinical Evidence Summary: COACH intensive (Jaarsma 2008): Long Home based MDT (MDThome) vs Cardiology clinic in high risk HF Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE) Relative effect Anticipated absolute effects Risk with cardiology clinic Risk difference with MDThome (95% CI) LOWa, b rate ratio 1.10 (from 44 fewer to 299 more) Referral and approach to care Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE) Relative effect Anticipated absolute effects Risk with cardiology clinic Risk difference with MDThome (95% CI) 18 months due to risk of bias, imprecision LOWa, b due to risk of bias, imprecision (from 105 fewer to 19 more) (a) Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias. (b) Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both. 