Adults with CKD and high proteinuria (PCR >0.22 g/g and PE >0.3 g/d), low MAP target (<92 mm Hg) versus standard MAP target (102 107 mm Hg) Table S60. Adults with CKD, ACEi versus placebo or standard of care Table S61. Adults with CKD, ARB versus placebo or standard of care Table S62. Adults with CKD, aldosterone antagonist versus placebo or standard of care Table S63. Adults with CKD, beta-blocker versus placebo or standard of care Table S64. Adults with CKD, beta-blocker versus RASi Table S65. Adults with CKD, calcium channel blockers versus placebo Table S66. Adults with CKD, calcium channel blockers versus RASi Table S67. Adults with CKD, direct renin inhibitor versus placebo Table S68. Adults with CKD, direct renin inhibitor versus RASi Table S69. Adults with CKD, direct renin inhibitor D ACEi or ARB versus placebo or standard of care Table S70. Adults with CKD, diuretics versus RASi Table S71. Older adults with CKD (65 85 years old), high-dose ARB versus calcium channel blocker combined with ARB Table S72. Adults with CKD, type 2 diabetes, and moderately increased albuminuria, calcium channel blockers D RAS blockade versus RAS blockade Table S73. Adults with CKD and chronic hyperkalemia, potassium binder versus placebo Table S74. Adults with CKD and chronic hyperkalemia, calcium polystyrene sulphonate (CPS) versus sodium polystyrene sulphonate (SPS) Table S75. Adults with CKD without diabetes, lower MAP (<92 mm Hg) target versus higher MAP (102 107 mm Hg) target Table S76. Adults with CKD and proteinuria (>1g/24 h for at least 3 months) without diabetes, low blood pressure target (<130/80 mm Hg) versus standard diastolic blood pressure target (<90 mm Hg) Table S77. Adults with CKD without diabetes, lower blood pressure target ( 120 mm Hg) versus standard blood pressure target Table S78. 