ISBN: 978-1-4731-3093-7 Chronic Heart Failure Contents NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: 978-1-4731-3093-7 Contents Guideline committee members 11 NGC technical team members 11 Co-optees 12 Peer reviewers 12 Acknowledgements 13 1 Guideline summary 14 1.1 Full list of recommendations 14 1.2 Diagnostic algorithm 23 1.4 Key research recommendations 24 2.1 Diagnosis and definition of chronic heart failure 26 2.3 Definition of a specialist 27 2.4 Definitions used in the guideline 28 2.5 Rationale for the update 29 3 Development of the guideline 30 3.1 What is a NICE guideline? 30 3.3 Who developed this guideline? 31 3.3.1 What this guideline covers 31 3.3.2 What this guideline does not cover 32 3.3.3 Relationships between the guideline and other NICE guidance 33 4.1 Developing the review questions and outcomes 34 4.2 Searching for evidence 41 4.2.1 Clinical literature search 41 4.2.2 Health economic literature search 42 4.3 Identifying and analysing evidence of effectiveness 42 4.3.1 Inclusion and exclusion criteria 43 4.3.2 Type of studies 44 4.3.3 Methods of combining clinical studies 44 4.3.4 Appraising the quality of evidence by outcomes 48 4.3.5 Publication bias 57 4.3.6 Assessing clinical importance 57 Chronic Heart Failure Contents NICE 2018. All rights reserved. Subject to Notice of rights. 