It should be noted that 45% of the group assigned to medical therapy ultimately underwent revascularization because of refractory symptoms. Considerable evidence indicates that elderly patients have higher mortality following PCI and CABG than do younger patients, and the risk appears to rise monotonically when .65 years of age.1144 1147,1164 1166 Compared with patients #65 years of age, adjusted odds of short-term mortality after PCI among patients between the ages of 60 and 80 have ranged from 2.2 to 7.6 in various registries, and the odds of death among those $80 years have ranged from 2.7 to .13. Unfortunately, far fewer data are available on the outcomes of elderly patients undergoing CABG, and much of it could be outdated. On the basis of data from 16 120 patients entered into the New York State registry, the odds of in-hospital mortality rose 8% per year of age .60 years (OR: 1.08; 95% CI: 1.06 to 1.09).1150 On the other hand, in an analysis of 505 645 records from the registry maintained by the STS, age was not found to be a predictor of mortality.1167 In older studies, elderly patients were reported to have favorable results after CABG,1168,1169 and long-term survival rates for elderly pa- tients with SIHD treated medically versus surgically were Older adults constitute a growing proportion of patients with SIHD. On the basis of the available data, it is recom- mended that management by GDMT be the initial approach in most patients. Given concerns about higher mortality rate, Fihn et al Stable Ischemic Heart Disease: Full Text e423 particularly in patients .75 or 80 years of age, decisions to recommend revascularization should be undertaken only after careful consideration of patient preferences, functional capac- ity, quality-of-life and end-of-life issues, as well as therapeu- 5.12.3. 