Short-Term Risk of Death or Nonfatal MI in Patients With UA/NSTEMI Feature High Risk Intermediate Risk Low Risk No high- or intermediate-risk features are present, but patient may have any of the following: At least 1 of the following features must be present: No high-risk features are present, but patient must have 1 of the following: History Accelerating tempo of ischemic symptoms in preceding 48 h Prior MI, peripheral or cerebrovascular disease, or CABG Prior aspirin use N/A Characteristics of pain Prolonged ongoing (.20 min) rest pain Prolonged (.20 min) rest angina, now resolved, with moderate or high likelihood of CAD Rest angina (.20 min) or relieved with rest or sublingual NTG Nocturnal angina New-onset or progressive CCS Class III or IV angina in previous 2 wk without prolonged (.20 min) rest pain but with intermediate or high likelihood of CAD Increased angina frequency, severity, or duration Angina provoked at a lower threshold New-onset angina with onset 2 wk to 2 mo before presentation Clinical findings Pulmonary edema, most likely due to ischemia New or worsening mitral regurgitation murmur S3 or new/worsening rales Hypotension, bradycardia, or tachycardia Age .75 y Age .70 y N/A ECG Angina at rest with transient ST-segment changes .0.5 mm Bundle-branch block, new or presumed new Sustained ventricular tachycardia T-wave changes Pathological Q waves or resting ST-depression ,1 mm in multiple lead groups (anterior, inferior, lateral) Normal or unchanged ECG Cardiac markers Elevated cardiac TnT, TnI, or CK-MB (ie, TnT or TnI .0.1 ng/mL) Slightly elevated cardiac TnT, TnI, or CK-MB (ie, TnT .0.01 but ,0.1 ng/mL) Normal Estimation of the short-term risks of death and nonfatal cardiac ischemic events in UA or NSTEMI is a complex multivariable problem that cannot be fully specified in a table such as this. Therefore, the table is meant to offer general guidance and illustration rather than rigid algorithms. 