Transfer to a PCI-Capable Hospital After Fibrinolytic Therapy See Figure 2. 5.3.1. Transfer of Patients With STEMI to a PCI-Capable Hospital for Coronary Angiography After Fibrinolytic Therapy: Recommendations See Table 8 for a summary of recommendations from this section; Online Data Supplement 4 for additional data on early catheterization and rescue PCI for fibrinolytic failure in the stent era; and Online Data Supplement 5 for additional Table 7. Adjunctive Antithrombotic Therapy to Support Reperfusion With Fibrinolytic Therapy COR LOE References Antiplatelet therapy Aspirin 81- to 325-mg daily maintenance dose (indefinite) I A 308, 330, 331 81 mg daily is the preferred maintenance dose receptor inhibitors Clopidogrel: I A 330, 331 Age 75 y: 300-mg loading dose Followed by 75 mg daily for at least 14 d and up to 1 y in absence of bleeding I A (14 d) 330, 331 C (up to 1 y) N/A Age >75 y: no loading dose, give 75 mg I A 330, 331 Followed by 75 mg daily for at least 14 d and up to 1 y in absence of bleeding I A (14 d) 330, 331 C (up to 1 y) N/A Anticoagulant therapy UFH: I C N/A Weight-based IV bolus and infusion adjusted to obtain aPTT of 1.5 to 2.0 times control for 48 h or until revascularization. IV bolus of 60 U/kg (maximum 4000 U) followed by an infusion of 12 U/kg/h (maximum 1000 U) initially, adjusted to maintain aPTT at 1.5 to 2.0 times control (approximately 50 to 70 s) for 48 h or until revascularization. 