Nevertheless, these CPGs were the product of a lengthy and rigorous review by a multidisciplinary panel of experts, and approved by all three participating societies. All future STS CPGs appearing in The Annals of Thoracic Surgery will be developed in accordance to the aforementioned Position Statement. This article is copublished in The Annals of Thoracic Surgery, Anesthesia & Analgesia, and the Journal of ExtraCorporeal Technology. The Society of Thoracic Surgeons requests that this document be cited as follows: Shore-Lesserson L, Baker RA, Ferraris VA, Greilich PE, Fitzgerald D, Roman P, Hammon JW. The Society of Thoracic Surgeons, The Society of Cardiovascular Anesthesiologists, and The American Society of Extra- Corporeal Technology: clinical practice guidelines anticoagulation dur- ing cardiopulmonary bypass. Ann Thorac Surg 2018;105:650 62. Address correspondence to Dr Shore-Lesserson, Department of Anes- thesiology, Northshore University Hospital, 300 Community Dr, Man- hasset, NY 11030; email: lshoreless@northwell.edu. The Appendix and Supplemental Tables can be viewed in the online version of this article [https://doi.org/10. 1016/j.athoracsur.2017.09.061] on http://www.annals thoracicsurgery.org. 2018 by The Society of Thoracic Surgeons, International Anesthesia Research Society, and the American Society of ExtraCorporeal Technology 0003-4975/$36.00 Published by Elsevier Inc. https://doi.org/10.1016/j.athoracsur.2017.09.061 REPORT Force on Practice Guidelines. Recommendations were written in the three following areas: (1) heparin dosing and monitoring for initiation and maintenance of CPB; (2) heparin contraindications and heparin alternatives; and (3) reversal of anticoagulation during cardiac operations. It is hoped that this guideline will serve as a resource and will stimulate investigators to conduct more research and to expand on the evidence base on the topic of anti- coagulation therapy for CPB. 