Weight reduction in overweight or obese, an appropriate diet, and moderation of alcohol intake are recommended in patients with hypertension. Thiazide or thiazide-like diuretics can be useful for BP control and to reverse mild volume overload and associated symptoms in symptomatic patients with HF with volume overload. Loop diuretics, which are the preferred agents for treatment of congestion in symptomatic patients with HF, are less effective than thiazide or thiazide-like diuretics in lowering BP. Addition of hydralazine isosorbide to the background therapy with ACE inhibitor or ARB and -blocker may be beneficial for BP control in nonblack patients with HFrEF and hypertension. Drugs to avoid in patients with HF and hypertension include nondihydropyridine calcium channel blockers (eg, verapamil and diltiazem) and moxonidine. An attempt should be made to avoid -adrenergic blockers such as doxazosin; they might be used only if other drugs for the management of hypertension and HF are inadequate to achieve BP control at maximum tolerated doses. ACE indicates angiotensin-converting enzyme; ARB, angiotensin receptor blocker; BP, blood pressure; COR, Class of Recommendation; GDMT, guideline- directed medical therapy; HF,heart failure; HFrEF,heart failure with reduced ejection fraction; LOE,Level of Evidence; and NYHA,NewYork HeartAssociation. Bozkurt et al ally the main focus of the initial treatment of patients with established HF, and the standard treatment of HF usually lowers BP. This is supported by the observation that SBP has usually been lowered to a normal range of 110 to 130 mmHg in most successful HF treatment trials with After optimization of HF treatment, if BP is not controlled, further treatment strategies target- ing both BP and HF can be used. 