In addition, a min- eralocorticoid receptor antagonist such as spironolactone or eplerenone can be effective in lowering BP in the patient with resistant hypertension, particularly in the setting of LV dys- function, while affording cardiovascular benefits, including reduced myocardial fibrosis, prevention or reversal of cardiac remodeling, or a reduction in arrhythmogenesis.235 Hypertension Management Recommendations 1. -Blockers should be administered as soon as possi- ble after CABG, in the absence of contraindications, to reduce the risk of postoperative AF and to facili- tate BP control early after surgery (Class I; Level of Evidence A). 2. ACE inhibitor therapy should be administered after CABG for patients with recent MI, LV dysfunction, diabetes mellitus, and chronic kidney disease, with careful consideration of renal function in determin- ing the timing of initiation and dose selection after surgery (Class I; Level of Evidence B). 3. With the use of antihypertensive medications, it is reasonable to target a BP goal of <140/85 mmHg after CABG; however the ideal BP target has not been formally evaluated in the CABG population (Class IIa; Level of Evidence B). 4. It is reasonable to add a calcium channel blocker or a diuretic agent as an additional therapeutic choice if the BP goal has not yet been achieved in the peri- operative period after CABG despite -blocker ther- apy and ACE inhibitor therapy as appropriate (Class IIa; Level of Evidence B). 5. In the absence of prior MI or LV dysfunction, anti- hypertensive therapies other than -blockers should be considered for chronic hypertension manage- ment long term after CABG (Class IIb; Level of Evidence B). 6. 