First, using a meta-analysis cumulative OR for stroke as the start- ing point, they found that preeclampsia increased the odds of stroke by 1.55-fold after correction for cardiovascular risk factors (interquartile range 1.76 1.98). This result suggests Table 5. Adverse Pregnancy Outcomes and Future Hypertension Study Date and First Author Total No. of Subjects Study Design Pregnancy Outcome Mean Follow-up, y RR or OR of Hypertension 815 Prospective cohort Preeclampsia and eclampsia 359 Prospective and retrospective cohort 60 Retrospective cohort Preeclampsia and eclampsia CI indicates confidence interval; OR, odds ratio; and RR, risk ratio. Adapted from Garovic et al149 with kind permission from Springer Science+Business Media. Authorization for this adaptation has been obtained both from the owner of the copyright in the original work and from the owner of copyright in the translation or adaptation. Bushnell et al Guidelines for Prevention of Stroke in Women 1555 that CVD risk factors antecedent to pregnancy did not fully explain the risk for CVD after preeclampsia. They hypoth- esized that preeclampsia/eclampsia is a risk factor rather than a marker for stroke and CVD. The authors then calculated the effect of literature-based cumulative benefits of lifestyle inter- ventions (dietary habits, exercise, and smoking cessation) on this risk for stroke with preeclampsia. They found the OR for the effect of lifestyle interventions on the risk for CVD after a preeclamptic pregnancy to be 0.91 (interquartile range, 0.87 0.96), which suggests that these interventions could reduce the risk of stroke in this population. 