Eur Respir J. 2013;42(1):134-144. 126. Chan CM, Woods C, Shorr AF. The validation and reproducibility of the pulmonary embolism severity index. J Thromb Haemost. 2010;8(7):1509-1514. 127. Jimenez D, Aujesky D, Moores L, et al. Simpli cation of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med. 2010;170(15):1383-1389. 128. Moores L, Aujesky D, Jimenez D, et al. Pulmonary Embolism Severity Index and troponin testing for the selection of low-risk patients with acute symptomatic pulmonary embolism. J Thromb Haemost. 2010;8(3):517-522. 129. Ozsu S, Abul Y, Orem A, et al. Predictive value of troponins and simpli ed pulmonary embolism severity index in patients with normotensive pulmonary embolism. Multidisc Respir Medic. 2013;8(1):34. 130. Righini M, Roy PM, Meyer G, Verschuren F, Aujesky D, Le Gal G. The Simpli ed Pulmonary Embolism Severity Index (PESI): validation of a clinical prognostic model for pulmonary embolism. J Thromb Haemost. 2011;9(10):2115-2117. 131. Zondag W, den Exter PL, Crobach MJ, et al. Comparison of two methods for selection of out of hospital treatment in patients with acute pulmonary embolism. Thromb Haemost. 2013;109(1):47-52. 132. Jimenez D, Uresandi F, Otero R, et al. Troponin-based risk strati cation of patients with acute nonmassive pulmonary embolism: systematic review and metaanalysis. Chest. 2009;136(4):974-982. 133. Lankeit M, Jimenez D, Kostrubiec M, et al. Validation of N-terminal pro-brain natriuretic peptide cut-off values for risk strati cation of pulmonary embolism. Eur Respir J. 2014;43(6):1669-1677. 134. Becattini C, Agnelli G, Germini F, Vedovati MC. Computed tomography to assess risk of death in acute pulmonary embolism: a meta-analysis. Eur Respir J. 2014;43(6):1678-1690. 135. Coutance G, Cauderlier E, Ehtisham J, Hamon M, Hamon M. The prognostic value of markers of right ventricular dysfunction in pulmonary embolism: a meta-analysis. Critical care. 2011;15(2):R103. 136. Spirk D, Aujesky D, Husmann M, et al. 