The Comprehensive RWI Data Supplement table is avail- able with this article at http://circ.ahajournals.org/lookup/ suppl/doi:10.1161/CIR.0000000000000509/-/DC1. The Data Supplement is available with this article at CIR.0000000000000509/-/DC2. This article has been copublished in the Journal of the American College of Cardiology and the Journal of Cardiac Failure. Copies:ThisdocumentisavailableontheWorldWideWeb sites of the American College of Cardiology (www.acc.org), the American Heart Association (professional.heart.org), and the Heart Failure Society of America (www.hfsa.org). A copy of the document is available at http://professional. heart.org/statements by selecting either the By Topic link or the By Publication Date link. To purchase addi- tional reprints, call 843-216-2533 or e-mail kelle.ramsay@ wolterskluwer.com. Expert peer review of AHA Scientific Statements is con- ducted by the AHA Office of Science Operations. For more on AHA statements and guidelines development, visit http:// professional.heart.org/statements and select the Policies and Development link. Permissions: Multiple copies, modification, alteration, enhancement, and/or distribution of this document are not permitted without the express permission of the American Heart Association. Instructions for obtaining permission are located at http://www.heart.org/HEARTORG/General/Copyright- Permission-Guidelines_UCM_300404_Article.jsp. A link to the Copyright Permissions Request Form appears on the right side of the page. Circulation is available at http://circ.ahajournals.org. *Former Task Force member; current member during the writing effort. III: Harm B-R In patients with NYHA class II IV HFrEF and central sleep apnea, adaptive servo-ventilation causes harm.203 NEW: New data demonstrate a signal of harm when adaptive servo-ventilation is used for central sleep apnea. 