Anderson CS, Arima H, Lavados P, Billot L, Hackett ML, Olavarr a VV, Mu oz Venturelli P, Brunser A, Peng B, Cui L, et al; HeadPoSTInvestigatorsandCoordinators.Cluster-randomized,crossover trial of head positioning in acute stroke. N Engl J Med. 2017;376:2437 241. Alexandrov AW, Tsivgoulis G, Hill MD, Liebeskind DS, Schellinger P, Ovbiagele B, Arthur AS, Caso V, Nogueira RG, Hemphill JC 3rd, et al. HeadPoST: rightly positioned, or flat out wrong? Neurology. 242. Olavarr a VV, Lavados PM, Mu oz-Venturelli P, Gonz lez F, Gaete J, Martins S, Arima H, Anderson CS, Brunser AM. Flat-head positioning increases cerebral blood flow in anterior circulation acute ischemic stroke: a cluster randomized phase IIb trial. Int J Stroke. 2018;13:600 243. Stead LG, Gilmore RM, Vedula KC, Weaver AL, Decker WW, Brown RD Jr. Impact of acute blood pressure variability on is- chemic stroke outcome. Neurology. 2006;66:1878 1881. doi: 244. Horn J, de Haan RJ, Vermeulen M, Limburg M. Very Early Nimodipine Use in Stroke (VENUS): a randomized, double-blind, placebo-controlled trial. Stroke. 2001;32:461 465. doi: 10.1161/01.str.32.2.461 245. Schrader J, L ders S, Kulschewski A, Berger J, Zidek W, Treib J, Einh upl K, Diener HC, Dominiak P; on behalf of the Acute Candesartan Cilexetil Therapy in Stroke Survivors Study Group. The ACCESS Study: evaluation of Acute Candesartan Cilexetil Therapy in Stroke Survivors. 246. Potter JF, Robinson TG, Ford GA, Mistri A, James M, Chernova J, Jagger C. Controlling Hypertension and Hypotension Immediately Post- Stroke (CHHIPS): a randomised, placebo-controlled, double-blind pilot 247. Robinson TG, Potter JF, Ford GA, Bulpitt CJ, Chernova J, Jagger C, James MA, Knight J, Markus HS, Mistri AK, et al; COSSACS Investigators. Effects of antihypertensive treatment after acute stroke in the Continue or Stop Post-Stroke Antihypertensives Collaborative Study (COSSACS): a prospective, randomised, open, blinded-endpoint trial. Lancet Neurol. 2010;9:767 775. doi: 10.1016/S1474-4422(10)70163-0 248. 