Other researchers participated to fulfill requirements of an academic degree or program. Conflicts of interest of all participants were managed according to ASH policies based on recommendations of the Institute of and the Guidelines International Network.5 At the time of appointment, a majority of the guideline panel, including the chair and the vice chair, had no conflicts of interest as defined and judged by ASH, that is, no current material interest in any commercial entity with a product that could be affected by the guidelines. Some panelists disclosed new interests or relation- ships during the development process, but the balance of the majority was maintained. Before appointment to the panel, individuals disclosed both financial and nonfinancial interests. Members of the VTE Guideline Coordination Panel reviewed the disclosures and judged which interests were conflicts and should be managed. Supplement 2 provides the complete Disclosure of Interests forms of all panel members. In part A of the forms, individuals disclosed material interests for 2 years prior to appointment. In part B, they disclosed interests that were not mainly financial. Part C summarizes ASH decisions about which interests were judged to be conflicts. Part D describes new interests disclosed by individuals after appointment. Recusal was also used to manage conflicts of interest. During all deliberations, panel members with a current, direct financial interest in a commercial entity with any product that could be affected by the guidelines were recused from making judgments about relevant recommendations.5,18-20 The Evidence-to-Decision (EtD) framework for each recommendation describes which individuals were recused from making judgments about each recommendation. None of the McMaster-affiliated researchers who supported the guideline development process had any current, material interest in a commercial entity with any product that could be affected by the guidelines. 