A relationship is considered to be significant if (a) the person receives $5000 or more during any 12-month period, or 5% or more of the person s gross income; or (b) the person owns 5% or more of the voting stock or share of the entity, or owns $5000 or more of the fair market value of the entity. A relationship is considered to be modest if it is less than significant under the preceding definition. *Modest. Significant. Appendix 2. Continued Peer reviewer Employment Research grant Other research support Speakers bureau/ honoraria Expert witness Ownership interest Consultant/advisory board Other CLINICAL STATEMENTS AND GUIDELINES Kleindorfer REFERENCES 1. Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Delling FN, et al; on behalf of the American Heart Association Council on Epidemiology and Prevention Sta- tistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics 2020 update: a report from the American Heart Association. 2. Kleindorfer D, Panagos P, Pancioli A, Khoury J, Kissela B, Woo D, Schneider A, Alwell K, Jauch E, Miller R, et al. Incidence and short-term prognosis of transient ischemic attack in a population-based study. Stroke. 3. Johnston SC, Gress DR, Browner WS, Sidney S. Short-term prognosis after emergency department diagnosis of TIA. JAMA. 2000;284:2901 2906. 4. Amarenco P; Steering Committee Investigators of the TIAregistry.org. Risk of stroke after transient ischemic attack or minor stroke. N Engl J Med. 5. Hong KS, Yegiaian S, Lee M, Lee J, Saver JL. Declining stroke and vascular event recurrence rates in secondary prevention trials over the past 50 years and consequences for current trial design. Circulation. 2011;123:2111 5a. 