Obesity-related hypertension: epidemiology, pathophysiol- ogy, and clinical management. Am J Hypertens. 2010;23:1170 1178. 44. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Boudier HA, Zanchetti A; ESH-ESC Task Force on the Management of Arterial Hypertension. 2007 ESH-ESC practice guidelines for the management of arterial hyperten- sion: ESH-ESC Task Force on the Management of Arterial Hypertension. J Hypertens. 2007;25:1751 1762. 45. Sharma AM, Pischon T, Engeli S, Scholze J. Choice of drug treatment for obesity-related hypertension: where is the evidence? J Hypertens. 2001;19:667 674. 46. Elliott WJ, Meyer PM. Incident diabetes in clinical trials of antihyperten- sive drugs: a network meta-analysis. Lancet. 2007;369:201 207. Rosendorff et al Treatment of Hypertension in Patients With CAD 1401 47. Frohlich ED. Clinical management of the obese hypertensive patient. Cardiol Rev. 2002;10:127 138. 48. Wenzel UO, Krebs C. Management of arterial hypertension in obese patients. Current Hypertens Rep. 2007;9:491 497. 49. Bangalore S, Messerli FH, Kostis JB, Pepine CJ. Cardiovascular pro- tection using beta-blockers: a critical review of the evidence. J Am Coll Cardiol. 2007;50:563 572. 50. Anderson JL, Halperin JL, Albert N, Bozkurt B, Brindis RG, Curtis LH, Demets D, Guyton RA, Hochman JS, Kovacs RJ, Ohman EM, Pressler SJ, Sellke FW, Shen WK. Management of patients with peripheral artery disease (compilation of 2005 and 2011 ACCF/AHA guideline recom- mendations): a report of the American College of Cardiology Foundation/ American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127:1425 1443. 51. Coffman JD. Vasodilator drugs for peripheral vascular disease. N Engl J Med. 1979;301:159 160. 52. Roberts DH,TsaoY, McLoughlin GA, BreckenridgeA. Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication. Lancet. 1987;2:650 653. 53. 