Patients with cardiac channelopathies (ie, long QT syndrome, catecholaminergic polymorphic ventricular tachycardia, Brugada syndrome, early repolarization syndrome, and short QT syndrome) and prior SCA have a significantly increased risk of subsequent SCA or SCD.S7.9-7 S7.9-13,S7.9-25 S7.9-28 Implantation of an ICD reduces the risk of death in high-risk patients.S7.9-9,S7.9-29 S7.9-31 Appropriate ICD therapy for VF/fast VT is reported in 8% to 33% of channelopathy patients, while inappropri- ate shocks and device complications are reported To mini- mize inappropriate shocks, concurrent beta block- ers in long QT syndrome and catecholaminergic polymorphic ventricular tachycardia patients, optimal device programming, and appropriate lead selection are necessary. Ventricular pacing without ICD implantation was associated with a significant risk of recurrent SCA or SCD in long QT syndrome patients.S7.9-37 S7.9-39 In selected patients with LQT1 in whom the SCA occurred in the absence of beta-blocker treatment, beta- blocker therapy is offered as an alternative to ICD CLINICAL STATEMENTS AND GUIDELINES implantation in patients who refuse to receive an 7.9.1. Specific Cardiac Channelopathy Syndromes 7.9.1.1. Congenital Long QT Syndrome Recommendations for Long QT Syndrome References that support the recommendations are summarized in Online Data Supplement 40. 