ISBN: Study design and sample size Finding Quality assessment Number of studies contributing to the finding Design Criteria Rating Overall assessment of confidence about relevance Adequacy Moderate concerns about adequacy Study design and sample size Finding Quality assessment Number of studies contributing to the finding Design Criteria Rating Overall assessment of confidence Wanting to deactivate focus groups Denmark People wanted to deactivate when they were bedridden with an extremely low quality of life Limitations Moderate concerns about methodological limitations VERY LOW Coherence Moderate concerns about coherence Relevance Moderate concerns about relevance Adequacy Moderate concerns about adequacy Finding 2: Discussions Advanced heart failure and palliative care Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: Study design and sample size Finding Quality assessment Number of studies contributing to the finding Design Criteria Rating Overall assessment of confidence Initiating the conversation USA Focus groups Some patients felt that healthcare professionals should start the conversation, whereas others felt that this would be emotionally distressing Limitations Minor concerns about methodological limitations LOW Coherence Minor concerns about coherence Relevance Moderate concerns about relevance Adequacy Moderate concerns about adequacy Study design and sample size Finding Quality assessment Number of studies contributing to the finding Design Criteria Rating Overall assessment of confidence Starting the conversation early Canada Interviews Some felt that discussions should be started early while they were able to make decisions Limitations Minor concerns about methodological limitations LOW Coherence Moderate concerns about coherence Relevance Moderate concerns Advanced heart failure and palliative care Chronic Heart Failure NICE 2018. All rights reserved. Subject to Notice of rights. 