were the chair and vice chair of the panel and led the panel meeting; and all au- thors approved the content. Conflict-of-interest disclosure: All authors were members of the guideline panel or members of the systematic review team or both. As such, they completed a disclosure of interest form, which was reviewed by ASH and is available as supplements 2 and 3. ORCID profiles: A.A., 0000-0002-0931-7851; Y.Z., 0000- 0002-4174-0641. Correspondence: Daniel M. Witt, Department of Pharmaco- therapy, College of Pharmacy, University of Utah, 30 South 2000 East, 4323, Salt Lake City, UT 84112; e-mail: dan.witt@pharm. utah.edu. References 1. Nutescu EA, Burnett A, Fanikos J, Spinler S, Wittkowsky A. Pharmacology of anticoagulants used in the treatment of venous thromboembolism [published correction appears in J Thromb Thrombolysis. 2016;42(2):296-311]. J Thromb Thrombolysis. 2016;41(1):15-31. 2. Schu nemann HJ, Wiercioch W, Etxeandia I, et al. Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise. CMAJ. 2014;186(3):E123-E142. 3. Institute of Medicine (US) Committee on Standards for Developing Trustworthy Clinical Practice Guidelines. Clinical Practice Guidelines We Can Trust. Graham R, Mancher M, Miller Wolman D, Greenfield S, Steinberg E, eds. Washington, DC: National Academies Press; 2011. 4. Qaseem A, Forland F, Macbeth F, Ollenschla ger G, Phillips S, van der Wees P; Board of Trustees of the Guidelines International Network. Guidelines International Network: toward international standards for clinical practice guidelines. Ann Intern Med. 2012;156(7): 525-531. 5. Schu nemann HJ, Al-Ansary LA, Forland F, et al; Board of Trustees of the Guidelines International Network. Guidelines International Network: principles for disclosure of interests and management of conflicts in guidelines. Ann Intern Med. 2015;163(7):548-553. 6. Alonso-Coello P, Oxman AD, Moberg J, et al; GRADE Working Group. GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 