There is, however, high-quality evidence for the ef cacy and safety of anticoagulant therapy in patients with larger PE, and this is expected to apply similarly to patients with subsegmental PE.1 Whether the risk of progressive or recurrent VTE is high enough to justify anticoagulation in patients with subsegmental PE is There were no episodes of recurrent VTE in retrospective reports that included about 60 TABLE 17 ] Summary of Findings: Elastic Compression Stockings vs No Elastic Compression Stockings to Prevent PTS of the Leg Outcomes No. of Participants (Studies) Follow-up Quality of the Evidence (GRADE) Relative Effect Anticipated Absolute Effects Risk with No Elastic Compression Stockings Risk Difference with Elastic Compression Stockings (95% CI) PTS Villalta Scorea Moderateb because of imprecision Moderate-Risk Populationd (from 67 fewer to 86 more) Recurrent VTE Moderateb,e because of imprecision Moderate-Risk Populationg (from 97 fewer to 65 more) Acute Leg Pain Moderatee,h because of imprecision The mean acute leg pain in the control groups was 1.13 leg pain severity assessed on an 11-point numerical pain rating scalei The mean acute leg pain in the intervention groups lower to 0.55 higher)i High The mean QoL in the intervention groups was 0.12 lower (1.11 lower to The basis for the assumed risk (eg, the median control group risk across studies) is provided in the footnotes. The corresponding risk (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). ECS elastic compression stockings; SF- 36 Short Form 36. See Table 1 and 14 legends for expansion of other abbreviations and GRADE Working Group grades of evidence. a For included studies, number of PTS events as assessed by Villalta s criteria b Low number of events. 