A recent large, ret- rospective, multinational study performed follow-up of 706 patients for a median of 40 months and tracked prespecified risk factors and conditions such as infections, trauma, OC use, pregnancy, puerperium, HT, recent neurosurgical proce- dures, and the presence of myeloproliferative neoplasms.199 Significantly more women than men had at least 1 risk factor Table 7. CVT and Recurrence Rates in Published Studies Recurrence Rate, % Study Subjects Enrolled, n % Female CVT Other Thrombosis Length of Follow-up Martinelli et al197 Coutinho et al193 94 72 NA NA NA Dentali et al199 CVT indicates cerebral venous thrombosis; ISCVT, International Study on Cerebral Vein and Dural Sinus Thrombosis; NA, not available; and VENOPORT, Cerebral Venous Thrombosis Portuguese Collaborative Study Group. Bushnell et al Guidelines for Prevention of Stroke in Women 1557 (61.0% versus 45.7%; P<0.05). Recurrence rates were again low (4.4% for recurrent CVT and 6.5% with a recurrent venous thromboembolism [VTE] in a different site), which led to an overall incidence of recurrence of 23.6 events per 1000 patient-years (95% CI, 17.8 28.7). Most events occurred after anticoagulation discontinuation. 