Clinical Review & Education Special Communication 2014 Guideline for Management of High Blood Pressure E12 JAMA Published online December 18, 2013 jama.com though the authors of this hypertension guideline did not conduct anevidencereviewoflifestyletreatmentsinpatientstakingandnot takingantihypertensivemedication,wesupporttherecommenda- tions of the 2013 Lifestyle Work Group.45 Therecommendationsfromthisevidence-basedguidelinefrom panel members appointed to the Eighth Joint National Committee (JNC 8) offer clinicians an analysis of what is known and not known about BP treatment thresholds, goals, and drug treatment strate- gies to achieve those goals based on evidence from RCTs. How- ever, these recommendations are not a substitute for clinical judg- ment, and decisions about care must carefully consider and incorporatetheclinicalcharacteristicsandcircumstancesofeachin- dividual patient. We hope that the algorithm will facilitate imple- mentationandbeusefultobusyclinicians.Thestrongevidencebase of this report should inform quality measures for the treatment of patients with hypertension. ARTICLE INFORMATION Published Online: December 18, 2013. doi:10.1001/jama.2013.284427. Author Affiliations: University of Iowa, Iowa City (James, Carter); University of Alabama at Birmingham School of Medicine (Oparil); Memphis Veterans Affairs Medical Center and the University of Tennessee, Memphis (Cushman); Johns Hopkins University School of Nursing, Baltimore, Maryland (Dennison-Himmelfarb); Kaiser Permanente, Anaheim, California (Handler); Medical University of South Carolina, Charleston (Lackland); University of Missouri, Columbia (LeFevre); Denver Health and Hospital Authority and the University of Colorado School of Medicine, Denver (MacKenzie); New York University School of Medicine, New York, New York (Ogedegbe); University of North Carolina at Chapel Hill (Smith); Duke University, Durham, North Carolina (Svetkey); Mayo Clinic College of Medicine, Rochester, Minnesota (Taler); University of Pennsylvania, Philadelphia (Townsend); Case Western Reserve University, Cleveland, Ohio (Wright); National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland (Narva); at the time of the project, National Heart, Lung, and Blood Institute, Bethesda, Maryland (Ortiz); currently with ProVation Medical, Wolters Kluwer Health, Minneapolis, Minnesota (Ortiz). 