Hirai S. Systemic inflammatory response syndrome after cardiac surgery under cardiopulmonary bypass. Ann Thorac Cardiovasc Surg. 2003;9:365 70. 56. Groom RC, Quinn RD, Lennon P, et al. Microemboli from cardiopul- monary bypass are associated with a serum marker of brain injury. J Extra Corpor Technol. 2010;42:40 4. 57. Liu YH, Wang DX, Li LH, et al. The effects of cardiopulmonary bypass on the number of cerebral microemboli and the incidence of cognitive dysfunction after coronary artery bypass graft surgery. Anesth Analg. 2009;109:1013 22. 58. Motallebzadeh R, Bland JM, Markus HS, et al. Neurocognitive function and cerebral emboli: randomized study of on-pump versus off-pump coronary artery bypass surgery. Ann Thorac Surg. 2007;83: 475 82. 59. Djaiani G, Fedorko L, Borger MA, et al. Continuous-flow cell saver reduces cognitive decline in elderly patients after coronary bypass surgery. Circulation. 2007;116:1888 95. 60. Rubens FD, Boodhwani M, Mesana T, et al. The cardiotomy trial: a randomized, double-blind study to assess the effect of processing of shed blood during cardiopulmonary bypass on transfusion and neuro- cognitive function. Circulation. 2007;116:I89 97. 61. Shroyer AL, Grover FL, Hattler B, et al. On-pump versus off-pump coronary-artery bypass surgery. N Engl J Med. 2009;361:1827 37. 62. Rinder CS, Fontes M, Mathew JP, et al. Neutrophil CD11b upregu- lation during cardiopulmonary bypass is associated with postoperative renal injury. Ann Thorac Surg. 2003;75:899 905. 63. Schurr UP, Zund G, Hoerstrup SP, et al. Preoperative administration of steroids: influence on adhesion molecules and cytokines after cardio- pulmonary bypass. Ann Thorac Surg. 2001;72:1316 20. 64. Werdan K, Pilz G, Muller-Werdan U, et al. Immunoglobulin G treatment of postcardiac surgery patients with score-identified severe systemic inflammatory response syndrome the ESSICS study. CritCare Med. 2008;36:716 23. 65. Chen YF, Tsai WC, Lin CC, et al. 