Capitalize on opportunities when patients are most predisposed to adherence n In-hospital/pre-discharge initiation following decompensation 2. Consider the patient s perspective n Start with the goals of therapy (feeling better and living longer) and then discuss how speci c actions (medication initiation, intensi cation, monitoring, and adherence) support those goals (example: ACC s My Heart Failure Action Plan) n Use decision aids when available (example: CardioSmart Heart Failure Resources) n Ask patient how they learn best and provide education accordingly n Use culturally relevant patient education materials 3. Simplify medication regimens whenever possible 4. Consider costs and access n Become familiar with and advocate for systems that help make cost sharing automatic, immediate, and transparent n Prescribe lower-cost medications if of similar ef cacy n Facilitate access to copay assistance n Discuss out-of-pocket copays proactively n Prescribe 90-day quantities for re lls 5. Communicate with other clinicians involved in care, ideally facilitated by electronic health records 6. Educate using practical, patient-friendly information n Provide a written explanation of the purpose of each medication prescribed n Plan pharmacist visits for complex medication regimens n Use the teach back principle to reinforce education 7. Recommend tools that support adherence in real time n Pill boxes to be lled by patient or care partner a week at a time n Alarms for each time of the day medications are due n Smartphone or other mobile health applications that provide an interactive platform for education, reminders, warnings, and adherence tracking 8. Consider behavioral supports n Motivational interviewing n Participate in engaged bene t designs 9. Anticipate problems n Communicate common side effects n Provide instructions on when to call for re lls or report problems n Remind patients using pharmacy assistance programs that re lls/reorders are not automatic 10. 