Like- wise, patients and clinicians need to be cognizant of reordering procedures, which becomes especially impor- tant if doses are changed re lls/reorders are not always sent and, unfortunately, re lls/reorders cannot be requested before the 60-day post-approval date. Supplemental Appendix 2 provides product-speci c in- formation on assistance in payment for newer HF thera- pies and appropriate use criteria to assist in the prior authorization process. 5.8. How to Manage the Increasing Complexity of HF Management The 2017 HF ECDP was motivated by an increasingly complex HFrEF management environment and the need to assist clinicians in navigating it (2). In the 3 years since its publication, GDMT for HFrEF now has additional medications that improve patient outcomes, thus further increasing the complexity of achieving target GDMT in all TABLE 12 Strategies to Reduce Patients Cost of Care n Coordinate care (including labs and imaging) among clinicians to mini- mize unnecessary duplication n Consider limitations of medication coverage (insurance, Medicaid, etc.) when prescribing n Use generic equivalents for GDMT whenever possible n Work with a pharmacist, social worker, or patient navigator to identify and navigate Patient Assistance Programs n Request price matching if a drug is found at a lower cost at another pharmacy GDMT guideline-directed medical therapy. 