AUTHOR RELATIONSHIPS WITH INDUSTRY AND OTHER ENTITIES (RELEVANT) 2021 UPDATE TO THE ACC EXPERT CONSENSUS DECISION PATHWAY ON OPTIMIZATION OF HEART FAILURE TREATMENT: ANSWERS TO 10 PIVOTAL QUESTIONS ABOUT HEART FAILURE WITH REDUCED EJECTION FRACTION To avoid actual, potential, or perceived con icts of interest that may arise as a result of industry relationships or personal interests among the writing committee, all members of the writing committee, as well as peer reviewers of the document, are asked to disclose all current healthcare-related relationships, including those existing 12 months before initiation of the writing effort. The ACC Task Force on Expert Consensus Decision Pathways reviews these disclosures to determine what companies make products (on market or in development) that pertain to the document under development. Based on this information, a writing committee is formed to include a majority of members with no relevant relationships with industry (RWI), led by a chair with no relevant RWI. RWI is reviewed on all conference calls and updated as changes occur. Author RWI pertinent to this document is disclosed in the table below and peer reviewer RWI is disclosed in Appendix 2. Addi- tionally, to ensure complete transparency, authors comprehensive disclosure information including RWI not pertinent to this document is available in a Supplemental Appendix 1. Disclosure information for the ACC Task Force on Expert Consensus Decision Pathways is also available online at http://www.acc.org/guidelines/about-guidelines-and-clinical- documents/guidelines-and-documents-task-forces, as well as the ACC disclosure policy for document development at http://www.acc.org/guidelines/about-guidelines-and-clinical-documents/relationships-with-industry-policy. J Maddox et al. 