ERC members may include methodologists, epidemiologists, healthcare providers, and biostatisticians. When a formal systematic review has been commissioned, the recom- mendations developed by the writing committee on the basis of the systematic review are marked with SR . Guideline-Directed Management and Therapy The term guideline-directed management and therapy (GDMT) encompasses clinical evaluation, diagnostic testing, and pharmacological and procedural treat- ments. For these and all recommended drug treat- ment regimens, the reader should confirm the dosage by reviewing product insert material and evaluate the treatment regimen for contraindications and interac- tions. The recommendations are limited to drugs, de- vices, and treatments approved for clinical use in the United States. Class of Recommendation and Level of Evidence The Class of Recommendation (COR) indicates the strength of the recommendation, encompassing the estimated magnitude and certainty of benefit in pro- portion to risk. The Level of Evidence (LOE) rates the quality of scientific evidence that supports the inter- vention on the basis of the type, quantity, and con- sistency of data from clinical trials and other sources Glenn N. Levine, MD, FACC, FAHA Chair, ACC/AHA Task Force on Clinical Practice Guidelines The purpose of this focused update is to update the 2013 ACCF/AHA Guideline for the Management of (2013 HF guideline) in areas in which new evidence has emerged since its publication. For this update and future heart failure (HF) guidelines, the Heart Failure Society of America (HFSA) has partnered with the ACC and AHA to provide coordinated guid- ance on the management of HF. 