Instruction: What was the name of the study?

Output: Trial of Preventing Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: Trial of Preventing Hypertension.


Instruction: When was the Am J Epidemiol published?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Epidemiol published?. ### Response: 2005.


Instruction: What was constructed by the Cochrane authors to assess for potential publication bias?

Output: Funnel plots

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was constructed by the Cochrane authors to assess for potential publication bias?. ### Response: Funnel plots.


Instruction: What was taken into consideration when assessing the quality of the evidence for strata containing more than 5 studies?

Output: Funnel plots were constructed by the Cochrane authors to assess for potential publication bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was taken into consideration when assessing the quality of the evidence for strata containing more than 5 studies?. ### Response: Funnel plots were constructed by the Cochrane authors to assess for potential publication bias.


Instruction: How many studies were included in the Cochrane review153?

Output: more than 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included in the Cochrane review153?. ### Response: more than 5.


Instruction: How many people with HF are hospitalised with signs and symptoms of decompensated?

Output: ≥ 18 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people with HF are hospitalised with signs and symptoms of decompensated?. ### Response: ≥ 18 years of age.


Instruction: What type of telephone support is used?

Output: Structured

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of telephone support is used?. ### Response: Structured.


Instruction: What is the average age of a person hospitalised with signs and symptoms of decompensated HF?

Output: 68.6 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average age of a person hospitalised with signs and symptoms of decompensated HF?. ### Response: 68.6 years.


Instruction: What percentage of the population in Germany is hospitalised for all-cause mortality?

Output: 71/29

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the population in Germany is hospitalised for all-cause mortality?. ### Response: 71/29.


Instruction: What type of support did Baker provide to people with HF from general and internal medicine and cardiology clinics?

Output: Structured telephone support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of support did Baker provide to people with HF from general and internal medicine and cardiology clinics?. ### Response: Structured telephone support.


Instruction: How old was the median age of people who had HF in 201123?

Output: 60.7 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old was the median age of people who had HF in 201123?. ### Response: 60.7 years.


Instruction: What was downgraded for risk of bias?

Output: Quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was downgraded for risk of bias?. ### Response: Quality of life.


Instruction: What was not matched at baseline and final values were reported?

Output: all scores

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not matched at baseline and final values were reported?. ### Response: all scores.


Instruction: How many people were discharged from acute care to home with a primary diagnosis of HF?

Output: 34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were discharged from acute care to home with a primary diagnosis of HF?. ### Response: 34.


Instruction: How old was the median age of people discharged to home?

Output: 75 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old was the median age of people discharged to home?. ### Response: 75 years.


Instruction: What is the percentage of all-cause mortality?

Output: 47/53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of all-cause mortality?. ### Response: 47/53.


Instruction: How many people with a  All-cause mortality  Strata: recent admission Bento 200933 Intervention: Structured telephone support?

Output: n=40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people with a  All-cause mortality  Strata: recent admission Bento 200933 Intervention: Structured telephone support?. ### Response: n=40.


Instruction: What is the name of the Advisory Committee on Immunization Practices?

Output: ACIP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Advisory Committee on Immunization Practices?. ### Response: ACIP.


Instruction: What are the recommendations of the ACIP?

Output: MMWR Prevention and Control of Influenza with Vaccines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations of the ACIP?. ### Response: MMWR Prevention and Control of Influenza with Vaccines.


Instruction: What year was the Influenza Season in the United States?

Output: 2012-2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the Influenza Season in the United States?. ### Response: 2012-2013.


Instruction: What year did the Centers for Disease Control and Prevention release their Influenza season report?

Output: 2012-2013 Influenza Season. Centers for Disease Control and Prevention. 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Centers for Disease Control and Prevention release their Influenza season report?. ### Response: 2012-2013 Influenza Season. Centers for Disease Control and Prevention. 2012.


Instruction: How long did it take to recover from an acute myocardial infarction and heart failure to return home?

Output: 30-day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to recover from an acute myocardial infarction and heart failure to return home?. ### Response: 30-day.


Instruction: What is the name of the study that published in 2009?

Output: Circ Cardiovasc Qual Outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that published in 2009?. ### Response: Circ Cardiovasc Qual Outcomes.


Instruction: What are the national patterns of risk-standard-ized mortality and readmission for for acute myocardial infarction and heart failure?

Output: Patterns of hospital perfor -mance in acute myocardial infarction and heart failure 30-day mortality and readmission. Circ Cardiovasc Qual Outcomes. 2009;2:407–13. 490. Bernheim SM, Grady JN, Lin Z, et al. National patterns of risk-standard-ized mortality and readmission for acute myocardial infarction and heart failure. Update on publicly reported outcomes measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the national patterns of risk-standard-ized mortality and readmission for for acute myocardial infarction and heart failure?. ### Response: Patterns of hospital perfor -mance in acute myocardial infarction and heart failure 30-day mortality and readmission. Circ Cardiovasc Qual Outcomes. 2009;2:407–13. 490. Bernheim SM, Grady JN, Lin Z, et al. National patterns of risk-standard-ized mortality and readmission for acute myocardial infarction and heart failure. Update on publicly reported outcomes measures.


Instruction: What type of programs are recommended for patients with UA/NSTEMI?

Output: Cardiac rehabilitation/secondary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of programs are recommended for patients with UA/NSTEMI?. ### Response: Cardiac rehabilitation/secondary prevention.


Instruction: What is recommended for those with multiple modifiable risk factors and moderate- to high-risk patients in whom exercise training is particularly warranted?

Output: Cardiac rehabilitation/secondary prevention programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for those with multiple modifiable risk factors and moderate- to high-risk patients in whom exercise training is particularly warranted?. ### Response: Cardiac rehabilitation/secondary prevention programs.


Instruction: What is recommended for patients with UA/NSTEMI?

Output: Cardiac rehabilitation/secondary prevention programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with UA/NSTEMI?. ### Response: Cardiac rehabilitation/secondary prevention programs.


Instruction: What are patients with multiple modifiable risk factors and those with moderate-to-high-risk patients in whom exercise training is warranted?

Output: ambulatory patients with current or prior symptoms of HF and reduced LVEF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with multiple modifiable risk factors and those with moderate-to-high-risk patients in whom exercise training is warranted?. ### Response: ambulatory patients with current or prior symptoms of HF and reduced LVEF.


Instruction: What is the name of the 2007 Chronic Angina Focused Update of the Guidelines for the Management of Patients With Chronic Stable Angina1111?

Output: ACC/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2007 Chronic Angina Focused Update of the Guidelines for the Management of Patients With Chronic Stable Angina1111?. ### Response: ACC/AHA.


Instruction: What type of programs are recommended for at-risk patients?

Output: Medically supervised programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of programs are recommended for at-risk patients?. ### Response: Medically supervised programs.


Instruction: What is beneficial as an adjunctive approach to improve clinical status in ambulatory patients with current or prior symptoms of HF and reduced LVEF?

Output: Exercise training

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial as an adjunctive approach to improve clinical status in ambulatory patients with current or prior symptoms of HF and reduced LVEF?. ### Response: Exercise training.


Instruction: What is Class I, Level of Evidence: B) AHA Evidence-Based Guidelines?

Output: Cardiovascular Disease Prevention in Women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Class I, Level of Evidence: B) AHA Evidence-Based Guidelines?. ### Response: Cardiovascular Disease Prevention in Women.


Instruction: What should be recommended to women with a recent acute coronary syndrome or coronary heart disease?

Output: A comprehensive risk-reduction regimen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be recommended to women with a recent acute coronary syndrome or coronary heart disease?. ### Response: A comprehensive risk-reduction regimen.


Instruction: What is LVEF 40%?

Output: left ventricular ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LVEF 40%?. ### Response: left ventricular ejection fraction.


Instruction: What is the ACC/AHA/SCAI 2007 Focused Update?

Output: Guidelines for Percutaneous Coronary Intervention1141

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA/SCAI 2007 Focused Update?. ### Response: Guidelines for Percutaneous Coronary Intervention1141.


Instruction: What type of programs are recommended for high-risk patients?

Output: Advising medically supervised programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of programs are recommended for high-risk patients?. ### Response: Advising medically supervised programs.


Instruction: What does ACC indicate?

Output: American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACC indicate?. ### Response: American College of Cardiology.


Instruction: AHA, American Heart Association.

Output: American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AHA, American Heart Association.. ### Response: American College of Cardiology.


Instruction: What does AMI stand for?

Output: acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AMI stand for?. ### Response: acute myocardial infarction.


Instruction: What is CABG a part of?

Output: coronary artery bypass graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CABG a part of?. ### Response: coronary artery bypass graft.


Instruction: Where is LVEF located?

Output: left ventricular ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is LVEF located?. ### Response: left ventricular ejection fraction.


Instruction: Who is the SCAI?

Output: Society for Cardiac Angiography and Interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the SCAI?. ### Response: Society for Cardiac Angiography and Interventions.


Instruction: What is UA/NSTEMI?

Output: unstable angina/non–ST-segment elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is UA/NSTEMI?. ### Response: unstable angina/non–ST-segment elevation myocardial infarction.


Instruction: What is unstable angina/non-ST-segment elevation myocardial infarction?

Output: UA/NSTEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unstable angina/non-ST-segment elevation myocardial infarction?. ### Response: UA/NSTEMI.


Instruction: When was Appendix A downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Appendix A downloaded?. ### Response: April 28, 2023.


Instruction: How is ATIII a slow inhibitor without heparin?

Output: Heparin binds to ATIII through a high-afﬁ  nity pentasaccharide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is ATIII a slow inhibitor without heparin?. ### Response: Heparin binds to ATIII through a high-afﬁ  nity pentasaccharide.


Instruction: How does Heparin bind to ATIII through a high-affi nity pentasaccharide?

Output: induces a con-formational change in ATIII

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Heparin bind to ATIII through a high-affi nity pentasaccharide?. ### Response: induces a con-formational change in ATIII.


Instruction: ATIII binds cova-lently to what enzyme?

Output: clotting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ATIII binds cova-lently to what enzyme?. ### Response: clotting.


Instruction: The heparin dissociates from what complex and can be reused?

Output: clotting enzyme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The heparin dissociates from what complex and can be reused?. ### Response: clotting enzyme.


Instruction: ATIII converts from a slow inhibitor to what?

Output: very rapid inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ATIII converts from a slow inhibitor to what?. ### Response: very rapid inhibitor.


Instruction: How much of the heparin molecules contain the high-affi nity pentasaccharide required for anticoagulant activity?

Output: one-third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the heparin molecules contain the high-affi nity pentasaccharide required for anticoagulant activity?. ### Response: one-third.


Instruction: What is the range of molecular weight of 15,000-30,000 kDa?

Output: 3,000-30,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the range of molecular weight of 15,000-30,000 kDa?. ### Response: 3,000-30,000.


Instruction: What is the high-affi nity pentasaccharide required for?

Output: anticoagulant activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the high-affi nity pentasaccharide required for?. ### Response: anticoagulant activity.


Instruction: What is cleared more rapidly than lower-molecular-weight moieties?

Output: High-molecular-weight moieties

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cleared more rapidly than lower-molecular-weight moieties?. ### Response: High-molecular-weight moieties.


Instruction: Who is from the University of New Mexico?

Output: Dr Garcia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is from the University of New Mexico?. ### Response: Dr Garcia.


Instruction: Where is the Thrombosis and Atherosclerosis Research Institute located?

Output: Hamilton, ON, Canada

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Thrombosis and Atherosclerosis Research Institute located?. ### Response: Hamilton, ON, Canada.


Instruction: What is the name of the hospital in Albuquerque, NM?

Output: University of New Mexico

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the hospital in Albuquerque, NM?. ### Response: University of New Mexico.


Instruction: Where is Addenbrooke's Hospital?

Output: Cambridge, England

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Addenbrooke's Hospital?. ### Response: Cambridge, England.


Instruction: Where is the Antithrombotic Therapy and Prevention of Thrombosis, 9th ed published?

Output: American College of Chest Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Antithrombotic Therapy and Prevention of Thrombosis, 9th ed published?. ### Response: American College of Chest Physicians.


Instruction: What organization received support from the National Heart, Lung, and Blood Institute?

Output: American College of Chest Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What organization received support from the National Heart, Lung, and Blood Institute?. ### Response: American College of Chest Physicians.


Instruction: What company provided educational grants?

Output: Bristol-Myers Squibb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What company provided educational grants?. ### Response: Bristol-Myers Squibb.


Instruction: What is the purpose of the American College of Chest Physician guidelines?

Output: intended for general information only

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of the American College of Chest Physician guidelines?. ### Response: intended for general information only.


Instruction: What is not medical advice?

Output: American College of Chest Physician guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not medical advice?. ### Response: American College of Chest Physician guidelines.


Instruction: What should always be sought for any medical condi-tion?

Output: American College of Chest Physician guidelines are intended for general information only, are not medical advice, and do not replace professional medical care and physician advice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should always be sought for any medical condi-tion?. ### Response: American College of Chest Physician guidelines are intended for general information only, are not medical advice, and do not replace professional medical care and physician advice.


Instruction: Where can the complete disclaimer for this guideline be accessed?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can the complete disclaimer for this guideline be accessed?. ### Response: http://chestjournal.chestpubs.org/content/141/2_suppl/1S..


Instruction: Who is David A. Garcia, MD?

Output: University of New Mexico

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is David A. Garcia, MD?. ### Response: University of New Mexico.


Instruction: What is the name of the University of New Mexico?

Output: Albuquerque, NM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the University of New Mexico?. ### Response: Albuquerque, NM.


Instruction: Where is David Garcia's address?

Output: Albuquerque, NM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is David Garcia's address?. ### Response: Albuquerque, NM.


Instruction: What is the name of the American College of Chest Physicians?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the American College of Chest Physicians?. ### Response: 2012.


Instruction: Who wrote the article about the American college of chest physicians?

Output: Kimberly Henricks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the article about the American college of chest physicians?. ### Response: Kimberly Henricks.


Instruction: When was the article written by Kimberly Henricks published?

Output: February 10, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the article written by Kimberly Henricks published?. ### Response: February 10, 2012.


Instruction: Preflight simulation testing or mandated supplemental oxygen are not usually indicated what?

Output: adequate hydration and movement during the flight are appropriate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preflight simulation testing or mandated supplemental oxygen are not usually indicated what?. ### Response: adequate hydration and movement during the flight are appropriate.


Instruction: Proper hydration and movement during the flight are appropriate, what are they?

Output: Preflight simulation testing or mandated supplemental oxygen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Proper hydration and movement during the flight are appropriate, what are they?. ### Response: Preflight simulation testing or mandated supplemental oxygen.


Instruction: Measurement of coagulation parameters in a patient with an elevated hematocrit >55% requires adjustment of what in the blood?

Output: anticoagulant volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Measurement of coagulation parameters in a patient with an elevated hematocrit >55% requires adjustment of what in the blood?. ### Response: anticoagulant volume.


Instruction: What percentage of hematocrit requires adjustment of anticoagulant volume in blood collection vials to account for reduced plasma volume in the draw?

Output: >55%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of hematocrit requires adjustment of anticoagulant volume in blood collection vials to account for reduced plasma volume in the draw?. ### Response: >55%.


Instruction: What indicates adult congenital heart disease and CHD?

Output: S3.16-24ACHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates adult congenital heart disease and CHD?. ### Response: S3.16-24ACHD.


Instruction: What is the name of the randomised trial of aperindopril-basedblood-pressure-loweringregimen?

Output: PROGRESS Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial of aperindopril-basedblood-pressure-loweringregimen?. ### Response: PROGRESS Collaborative Group.


Instruction: How many people had a previous stroke or transient ischaemic attack?

Output: 6,105

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people had a previous stroke or transient ischaemic attack?. ### Response: 6,105.


Instruction: What is a blood-pressure target in patients with recentlacunarstroke?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a blood-pressure target in patients with recentlacunarstroke?. ### Response: theSPS3randomisedtrial.Lancet.2013;382:507-15.


Instruction: What is the name of the randomised trial in patients with recentlacunarstroke?

Output: SPS3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial in patients with recentlacunarstroke?. ### Response: SPS3.


Instruction: When did theSPS3randomisedtrial take place?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did theSPS3randomisedtrial take place?. ### Response: 2016.


Instruction: How many patients were intolerant to angiotensin-convertingenzyme inhibitors?

Output: high-risk patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were intolerant to angiotensin-convertingenzyme inhibitors?. ### Response: high-risk patients.


Instruction: What is a randomised controlled trial?

Output: Ef-fectsoftheangiotensin-receptorblockertelmisartanoncardiovascu-lar events in high-risk patients intolerant to angiotensin-convertingenzyme inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomised controlled trial?. ### Response: Ef-fectsoftheangiotensin-receptorblockertelmisartanoncardiovascu-lar events in high-risk patients intolerant to angiotensin-convertingenzyme inhibitors.


Instruction: What is the name of the randomized controlled trial in which Intensivevs blood pressure control and cardiovascular disease out-comes are evaluated?

Output: Secondary Prevention of Small SubcorticalStrokes (SPS3)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial in which Intensivevs blood pressure control and cardiovascular disease out-comes are evaluated?. ### Response: Secondary Prevention of Small SubcorticalStrokes (SPS3).


Instruction: What is the name of the randomized trial in which verapamiladded-on trandolapril therapy is used in hypertensive type 2 diabetes patients with microalbuminuria?

Output: BENEDICT-B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial in which verapamiladded-on trandolapril therapy is used in hypertensive type 2 diabetes patients with microalbuminuria?. ### Response: BENEDICT-B.


Instruction: When was the BENEDICT-B trial conducted?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the BENEDICT-B trial conducted?. ### Response: 2011.


Instruction: What is the name of the study that investigated the cardiovascular outcomes of type 2 diabetes and nephropathy?

Output: RENAAL Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the cardiovascular outcomes of type 2 diabetes and nephropathy?. ### Response: RENAAL Study Investigators.


Instruction: What type of diabetes is the RENAAL Study Investigators studying?

Output: type 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes is the RENAAL Study Investigators studying?. ### Response: type 2.


Instruction: Which type of hypertension in Europe trial investigators followed up on a patient with systolic hypertension?

Output: isolatedsystolichypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which type of hypertension in Europe trial investigators followed up on a patient with systolic hypertension?. ### Response: isolatedsystolichypertension.


Instruction: Systolic Hypertension in Europe (Syst-Eur)Trial Investigators. Follow-up of renal function in treated and un-treatedolderpatientswithisolatedsystolichypertension. 2001;19:511-9. [PMID: 11288822]34. Peralta CA, McClure LA, Scherzer R, White CL, Shilipak M, et al. Effect of intensive versus usual blood pressure con-trolonkidneyfunctionam

Output: 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Systolic Hypertension in Europe (Syst-Eur)Trial Investigators. Follow-up of renal function in treated and un-treatedolderpatientswithisolatedsystolichypertension. 2001;19:511-9. [PMID: 11288822]34. Peralta CA, McClure LA, Scherzer R, White CL, Shilipak M, et al. Effect of intensive versus usual blood pressure con-trolonkidneyfunctionam. ### Response: 33.


Instruction: What is the secondary prevention of small subcorticalStrokes (SPS3) randomized trial called?

Output: CIRCULATIONAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the secondary prevention of small subcorticalStrokes (SPS3) randomized trial called?. ### Response: CIRCULATIONAHA.


Instruction: What is a post hoc analysis of the Secondary Prevention of Small Subcorticosteroid Strokes?

Output: PROGRESS Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a post hoc analysis of the Secondary Prevention of Small Subcorticosteroid Strokes?. ### Response: PROGRESS Collaborative Group.


Instruction: When was Circulation 133:584-91 published?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation 133:584-91 published?. ### Response: 2016.


Instruction: What is a lifestyle intervention for lowering blood pressure in patients with CKD not receiving dialysis?

Output: RAS inhibition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a lifestyle intervention for lowering blood pressure in patients with CKD not receiving dialysis?. ### Response: RAS inhibition.


Instruction: What are the additional outcomes listed in Table 1?

Output: fat mass, BP, quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the additional outcomes listed in Table 1?. ### Response: fat mass, BP, quality of life.


Instruction: Cochrane review Palmer SC, et al.

Output: Dietary interventions for adults with chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cochrane review Palmer SC, et al.. ### Response: Dietary interventions for adults with chronic kidney disease.


Instruction: What does exercise do in adults with CKD and hypertension?

Output: improve clinically relevant outcomes and decrease adverseeffects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does exercise do in adults with CKD and hypertension?. ### Response: improve clinically relevant outcomes and decrease adverseeffects.


Instruction: Does exercise improve clinical relevant outcomes and decrease adverseeffects?

Output: In adults with CKD and hypertension, does exercise improve clinically relevant outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Does exercise improve clinical relevant outcomes and decrease adverseeffects?. ### Response: In adults with CKD and hypertension, does exercise improve clinically relevant outcomes.


Instruction: How long is the duration of an exercise intervention?

Output: 8 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the duration of an exercise intervention?. ### Response: 8 weeks.


Instruction: What are the main outcomes of the RCT?

Output: fat mass, BP, quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the main outcomes of the RCT?. ### Response: fat mass, BP, quality of life.


Instruction: Who wrote Exercise training for adults with chronic kidney disease (Review)?

Output: Heiwe S and Jacobson SH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote Exercise training for adults with chronic kidney disease (Review)?. ### Response: Heiwe S and Jacobson SH.


Instruction: What is the Cochrane Database of Systematic Reviews?

Output: 2006:4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Cochrane Database of Systematic Reviews?. ### Response: 2006:4.


Instruction: How is blood pressure managed in patients with CKD?

Output: lower (intensive) BP targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is blood pressure managed in patients with CKD?. ### Response: lower (intensive) BP targets.


Instruction: What does lower BP targets do in patients with CKD?

Output: improve clinical ef ﬁcacyoutcomes and reduce adverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lower BP targets do in patients with CKD?. ### Response: improve clinical ef ﬁcacyoutcomes and reduce adverse effects.


Instruction: What does lowering BP target compared to standard BP goals improve?

Output: clinical ef ﬁcacyoutcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lowering BP target compared to standard BP goals improve?. ### Response: clinical ef ﬁcacyoutcomes.


Instruction: What are the two types of diabetes?

Output: T1D and T2D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two types of diabetes?. ### Response: T1D and T2D.


Instruction: What is the difference between the lower and lower BP targets?

Output: <140/80 mm Hg, <130/80

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between the lower and lower BP targets?. ### Response: <140/80 mm Hg, <130/80.


Instruction: Where are the critical and important outcomes listed?

Output: Table 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the critical and important outcomes listed?. ### Response: Table 1.


Instruction: What does RAS inhibition compared to placebo/no treatment or standard of care do in patients with CKD?

Output: improve clinicalefﬁcacy outcomes and reduce adverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does RAS inhibition compared to placebo/no treatment or standard of care do in patients with CKD?. ### Response: improve clinicalefﬁcacy outcomes and reduce adverse effects.


Instruction: What is CKD G1 – G5 without kidney transplant?

Output: Adults with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD G1 – G5 without kidney transplant?. ### Response: Adults with CKD.


Instruction: What are ACEi, ARB, aldosterone antagonists used for?

Output: Intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ACEi, ARB, aldosterone antagonists used for?. ### Response: Intervention.


Instruction: What are converting enzyme inhibitors and angiotensin II receptor antagonists for?

Output: preventing theprogression of diabetic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are converting enzyme inhibitors and angiotensin II receptor antagonists for?. ### Response: preventing theprogression of diabetic kidney disease.


Instruction: What is preventing the progression of diabetic kidney disease?

Output: Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preventing the progression of diabetic kidney disease?. ### Response: Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists.


Instruction: When was the Cochrane Database of Systematic Reviews published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Cochrane Database of Systematic Reviews published?. ### Response: 2011.


Instruction: What is the name of the Cochrane Database of Systematic Reviews?

Output: 2017:4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Cochrane Database of Systematic Reviews?. ### Response: 2017:4.


Instruction: What is renin angiotensin system antagonist?

Output: Aldosterone antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is renin angiotensin system antagonist?. ### Response: Aldosterone antagonists.


Instruction: What is the evidence for ethnic or racial influence on CKD mostly?

Output: epidemiological

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the evidence for ethnic or racial influence on CKD mostly?. ### Response: epidemiological.


Instruction: What is higher in a wide variety of non-white groups?

Output: The incidence of kidney failurerequiring dialysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is higher in a wide variety of non-white groups?. ### Response: The incidence of kidney failurerequiring dialysis.


Instruction: What is more common among African-Americans than whites in the United States?

Output: Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more common among African-Americans than whites in the United States?. ### Response: Hypertension.


Instruction: What does BP manifest with a higheraverage among blacks?

Output: Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does BP manifest with a higheraverage among blacks?. ### Response: Hypertension.


Instruction: Besides environmental and socioeconomic issues, what is gradually being collected?

Output: information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Besides environmental and socioeconomic issues, what is gradually being collected?. ### Response: information.


Instruction: What is MYH9?

Output: non-muscle myosinheavy chain 9 gene

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MYH9?. ### Response: non-muscle myosinheavy chain 9 gene.


Instruction: What was partly responsible for kidney disease in hypertensiveAfrican-Americans?

Output: Genetic variance in the non-muscle myosinheavy chain 9 gene

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was partly responsible for kidney disease in hypertensiveAfrican-Americans?. ### Response: Genetic variance in the non-muscle myosinheavy chain 9 gene.


Instruction: What is the name of the gene that is located upstream of MYH9?

Output: apolipoprotein L-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the gene that is located upstream of MYH9?. ### Response: apolipoprotein L-1.


Instruction: What are APOLI G1 and G2 allelesassociated with?

Output: focal segmental glomerulosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are APOLI G1 and G2 allelesassociated with?. ### Response: focal segmental glomerulosclerosis.


Instruction: The APOLI G1 and G2 allelesassociating with what type of glomerulosclerosis in African-Americans?

Output: focal segmental

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The APOLI G1 and G2 allelesassociating with what type of glomerulosclerosis in African-Americans?. ### Response: focal segmental.


Instruction: These variants seem toconfer resistance to what?

Output: Trypanosoma brucei rhodesiense

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: These variants seem toconfer resistance to what?. ### Response: Trypanosoma brucei rhodesiense.


Instruction: What hypothesis does not clarify the association between APOL1 and focalsegmental glomerulationsclerosis?

Output: Trypanosoma brucei rhodesiense

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What hypothesis does not clarify the association between APOL1 and focalsegmental glomerulationsclerosis?. ### Response: Trypanosoma brucei rhodesiense.


Instruction: Epidemiological evidence is suggestive of what kind of evidence?

Output: many otherethnic–racial differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Epidemiological evidence is suggestive of what kind of evidence?. ### Response: many otherethnic–racial differences.


Instruction: APOL1 and focalsegmental glomerulosclerosis?

Output: 440

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: APOL1 and focalsegmental glomerulosclerosis?. ### Response: 440.


Instruction: Evidence suggests many other ethnic–racial differences among individuals with what type of disease?

Output: CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence suggests many other ethnic–racial differences among individuals with what type of disease?. ### Response: CKD.


Instruction: What are the effects of BP on CKD progression?

Output: BP control on CKD progression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects of BP on CKD progression?. ### Response: BP control on CKD progression.


Instruction: What is the scientific community only scratching the surface of?

Output: links among BP, CKD, race, ethnicity, genes, and epigenetics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the scientific community only scratching the surface of?. ### Response: links among BP, CKD, race, ethnicity, genes, and epigenetics.


Instruction: What are some of the links between BP, CKD, race, ethnicity, genes, and epigenetics?

Output: kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the links between BP, CKD, race, ethnicity, genes, and epigenetics?. ### Response: kidney disease.


Instruction: What may become available in the future regarding how to modify BP control?

Output: evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may become available in the future regarding how to modify BP control?. ### Response: evidence.


Instruction: In themeantime, we must pay greater attention to what issues related to ethnicity?

Output: socioeconomicand environmental

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In themeantime, we must pay greater attention to what issues related to ethnicity?. ### Response: socioeconomicand environmental.


Instruction: What are more immediately amenable to modification?

Output: socioeconomicand environmental issues related to ethnicity or race

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are more immediately amenable to modification?. ### Response: socioeconomicand environmental issues related to ethnicity or race.


Instruction: What are the BARRIERS TO IMPLEMENTATION?

Output: guidelines on BP management in CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the BARRIERS TO IMPLEMENTATION?. ### Response: guidelines on BP management in CKD.


Instruction: Why is it ischallenging to implement recommendations and to achieve targets?

Output: lower BP targets in hypertensive African-Americans thanother racial groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is it ischallenging to implement recommendations and to achieve targets?. ### Response: lower BP targets in hypertensive African-Americans thanother racial groups.


Instruction: What is NNT?

Output: Number needed to treat

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NNT?. ### Response: Number needed to treat.


Instruction: How many patients would have to be treated to ensure 1 of them gets better?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients would have to be treated to ensure 1 of them gets better?. ### Response: 4.


Instruction: What is the average number of patients who need to be cured to get a positive outcome?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average number of patients who need to be cured to get a positive outcome?. ### Response: 4.


Instruction: How many people are needed to treat a stroke?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people are needed to treat a stroke?. ### Response: 20.


Instruction: The closer the NNT is to what, the better the treatment?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The closer the NNT is to what, the better the treatment?. ### Response: 1.


Instruction: To treat is how many?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To treat is how many?. ### Response: 20.


Instruction: What is the number needed to harm?

Output: absolute risk reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the number needed to harm?. ### Response: absolute risk reduction.


Instruction: Who is observed or certain factors are measured?

Output: Individuals or groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is observed or certain factors are measured?. ### Response: Individuals or groups.


Instruction: What would allow ‘nature’ or usual medical care to take its course?

Output: an observational study of a disease or treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would allow ‘nature’ or usual medical care to take its course?. ### Response: an observational study of a disease or treatment.


Instruction: Changes or differences in one characteristic are studied without intervening what?

Output: whether or not people received a specific treatment or intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Changes or differences in one characteristic are studied without intervening what?. ### Response: whether or not people received a specific treatment or intervention.


Instruction: There is a greater risk of selection bias than in what type of bias?

Output: experimental studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is a greater risk of selection bias than in what type of bias?. ### Response: experimental studies.


Instruction: Is there a greater risk of selection bias in experimental studies?

Output: There is a greater risk of selection bias than in experimental studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is there a greater risk of selection bias in experimental studies?. ### Response: There is a greater risk of selection bias than in experimental studies.


Instruction: What was the HR of simvastatin plus ezetimibe compared with placebo?

Output: 0.83

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of simvastatin plus ezetimibe compared with placebo?. ### Response: 0.83.


Instruction: What was driven by significant reductions in non-hemor-rhagic stroke and coronary revascularization?

Output: events (coronary death, MI, non-hemorrhagic stroke, or anyrevascularization) compared with placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was driven by significant reductions in non-hemor-rhagic stroke and coronary revascularization?. ### Response: events (coronary death, MI, non-hemorrhagic stroke, or anyrevascularization) compared with placebo.


Instruction: What did notreduce the risk of progression to end-stage renal disease requiring RRT?

Output: treatment with simvastatin plus ezetimibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did notreduce the risk of progression to end-stage renal disease requiring RRT?. ### Response: treatment with simvastatin plus ezetimibe.


Instruction: What was similar in participants assigned to treatment and to control?

Output: The risk of serious adverse events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was similar in participants assigned to treatment and to control?. ### Response: The risk of serious adverse events.


Instruction: Post hoc analyses of randomized trials of statin vs. placebo focus on what?

Output: the subset with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Post hoc analyses of randomized trials of statin vs. placebo focus on what?. ### Response: the subset with CKD.


Instruction: What do statins reduce the RR of cardiovascularevents to a similar extent among patients with and without CKD?

Output: risk of future coronary events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do statins reduce the RR of cardiovascularevents to a similar extent among patients with and without CKD?. ### Response: risk of future coronary events.


Instruction: Why is the absolute benefit of treatment larger in theformer?

Output: higher baseline risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the absolute benefit of treatment larger in theformer?. ### Response: higher baseline risk.


Instruction: What was the risk of adverse events associated with statin treatment similar to in participants with and without CKD?

Output: therisk of adverse events associated with statin treatmentappeared similar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of adverse events associated with statin treatment similar to in participants with and without CKD?. ### Response: therisk of adverse events associated with statin treatmentappeared similar.


Instruction: What percentage of the participants withCKD in these analyses had eGFR 45–59.9 ml/min/1.73 m2?

Output: most

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the participants withCKD in these analyses had eGFR 45–59.9 ml/min/1.73 m2?. ### Response: most.


Instruction: Why were larger in the former due to their higher baseline risk?

Output: absolute beneﬁt of treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were larger in the former due to their higher baseline risk?. ### Response: absolute beneﬁt of treatment.


Instruction: What is the absolute risk in people who are non-dialysis-dependent with eGFR o60 ml/min/1.73 m2agedZ50 years consistently greater than 10 per 1000 patient-years?

Output: knowledge of LDL-C is notrequired to gauge average coronary risk in this population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the absolute risk in people who are non-dialysis-dependent with eGFR o60 ml/min/1.73 m2agedZ50 years consistently greater than 10 per 1000 patient-years?. ### Response: knowledge of LDL-C is notrequired to gauge average coronary risk in this population.


Instruction: What is notrequired to gauge average coronary risk in this population?

Output: knowledge of LDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is notrequired to gauge average coronary risk in this population?. ### Response: knowledge of LDL-C.


Instruction: What did the WorkGroup judge was defensible for patients aged Z50 years based on the data presented above?

Output: increased simplicity of an age-basedapproach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the WorkGroup judge was defensible for patients aged Z50 years based on the data presented above?. ### Response: increased simplicity of an age-basedapproach.


Instruction: What is no evidence that ezetimibe monotherapy is effective?

Output: There is no evidence that ezetimibe monotherapy willimprove clinically relevant outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is no evidence that ezetimibe monotherapy is effective?. ### Response: There is no evidence that ezetimibe monotherapy willimprove clinically relevant outcomes.


Instruction: What does ezetimibe monotherapy not improve in patients with or without CKD?

Output: clinically relevant outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ezetimibe monotherapy not improve in patients with or without CKD?. ### Response: clinically relevant outcomes.


Instruction: What is notrecommended?

Output: ezetimibe monotherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is notrecommended?. ### Response: ezetimibe monotherapy.


Instruction: What is the subset with CKD?

Output: participants with CKD at baseline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the subset with CKD?. ### Response: participants with CKD at baseline.


Instruction: What do the large body of evidence from the general population trials collectively provide a strong rationale for?

Output: this recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the large body of evidence from the general population trials collectively provide a strong rationale for?. ### Response: this recommendation.


Instruction: What was recommended to treat eGFRZ60 ml/min/1.73 m2(GFR categories G1-G2)?

Output: a statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was recommended to treat eGFRZ60 ml/min/1.73 m2(GFR categories G1-G2)?. ### Response: a statin.


Instruction: What is the risk of future coronary events in patients aged Z50 yearswith CKD markedly increased?

Output: the rate of coronary death or non-fatal MIin this population exceeds 10 per 1000 patient-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of future coronary events in patients aged Z50 yearswith CKD markedly increased?. ### Response: the rate of coronary death or non-fatal MIin this population exceeds 10 per 1000 patient-years.


Instruction: The rate of coronary death or non-fatal MI in this population exceeds what?

Output: 10 per 1000 patient-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The rate of coronary death or non-fatal MI in this population exceeds what?. ### Response: 10 per 1000 patient-years.


Instruction: How many patients have CKD and eGFR Z60 ml/min/1.73 m2?

Output: Z50 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients have CKD and eGFR Z60 ml/min/1.73 m2?. ### Response: Z50 years.


Instruction: How many years before and after the publication of this guide-line should you assess the proportion of non-dialysis-dependentadults with eGFR o60 ml/min/1.73 m2that receive treatment with a statin or statin/ezetimibecombination?

Output: One year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years before and after the publication of this guide-line should you assess the proportion of non-dialysis-dependentadults with eGFR o60 ml/min/1.73 m2that receive treatment with a statin or statin/ezetimibecombination?. ### Response: One year.


Instruction: How old are adults with CKD and eGFR 460 ml/min/1.73 m2 that receive treatment with a statin?

Output: Z50 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are adults with CKD and eGFR 460 ml/min/1.73 m2 that receive treatment with a statin?. ### Response: Z50 years.


Instruction: How many years before and after the publication of this guideline, assess the proportion of adult kidney trans-plant recipients that get treatment with statins?

Output: One year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years before and after the publication of this guideline, assess the proportion of adult kidney trans-plant recipients that get treatment with statins?. ### Response: One year.


Instruction: How long before and after publication of this guideline should you assess the prevalence of statin use among non-dialysis-dependent adults aged 18-49 years withCKD?

Output: One year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before and after publication of this guideline should you assess the prevalence of statin use among non-dialysis-dependent adults aged 18-49 years withCKD?. ### Response: One year.


Instruction: What is knowncoronary disease (MI or coronary revascularization)?

Output: risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is knowncoronary disease (MI or coronary revascularization)?. ### Response: risk factors.


Instruction: What is the predicted 10-year risk of CHD death/non-fatal MI 410%?

Output: knowncoronary disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the predicted 10-year risk of CHD death/non-fatal MI 410%?. ### Response: knowncoronary disease.


Instruction: What is sufficiently high to justify prescription of statins in people aged Z50 with non-dialysis-dependentCKD or a kidney transplant?

Output: Coronary risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is sufficiently high to justify prescription of statins in people aged Z50 with non-dialysis-dependentCKD or a kidney transplant?. ### Response: Coronary risk.


Instruction: What may increase risk to justify statinprescription?

Output: cardiovascular risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may increase risk to justify statinprescription?. ### Response: cardiovascular risk factors.


Instruction: What is evidence that treatment withstatins improve in this population?

Output: vascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evidence that treatment withstatins improve in this population?. ### Response: vascular outcomes.


Instruction: What is the 10-year risk of non-fatal MI?

Output: 410%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 10-year risk of non-fatal MI?. ### Response: 410%..


Instruction: Who should not be started on statin or statin/ezetimibe treatment?

Output: Patients with dialysis-dependent CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should not be started on statin or statin/ezetimibe treatment?. ### Response: Patients with dialysis-dependent CKD.


Instruction: What should not be discontinued among existing users when dialysis treatment is initiated?

Output: statin or statin/ezetimibe treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be discontinued among existing users when dialysis treatment is initiated?. ### Response: statin or statin/ezetimibe treatment.


Instruction: What should be alert to the possibility of toxicity from substances that increase blood levels of statin?

Output: Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be alert to the possibility of toxicity from substances that increase blood levels of statin?. ### Response: Physicians.


Instruction: What should be undertaken of the SHARP study cohort to determine if there persists in major atherosclerotic events in the long-term?

Output: An extended observational study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be undertaken of the SHARP study cohort to determine if there persists in major atherosclerotic events in the long-term?. ### Response: An extended observational study.


Instruction: What significantly delays renal diseaseprogression in people with non-dialysis-dependent CKDand eGFR?

Output: LDL-C lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What significantly delays renal diseaseprogression in people with non-dialysis-dependent CKDand eGFR?. ### Response: LDL-C lowering.


Instruction: Where is the majority of early CKD managed?

Output: primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the majority of early CKD managed?. ### Response: primary care.


Instruction: Where should audits of pharmacological cholesterol-lowering treatment be undertaken?

Output: primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where should audits of pharmacological cholesterol-lowering treatment be undertaken?. ### Response: primary care.


Instruction: What should be pooled to undertake individual patientdata meta-analysis?

Output: Data from the AURORA, 4D and SHARP studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be pooled to undertake individual patientdata meta-analysis?. ### Response: Data from the AURORA, 4D and SHARP studies.


Instruction: What is a meta-analysis to assess thebenefits and risks of cholesterol-lowering treatment in people with dialysis-dependent CKD?

Output: individual patientdata

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis to assess thebenefits and risks of cholesterol-lowering treatment in people with dialysis-dependent CKD?. ### Response: individual patientdata.


Instruction: What is the name of the US Agency for Healthcare Research and Quality's report on preventive services?

Output: Preventive Services Task Force Recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the US Agency for Healthcare Research and Quality's report on preventive services?. ### Response: Preventive Services Task Force Recommendation.


Instruction: Where is the Preventive Services Task Force Recommendation located?

Output: Rockville, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Preventive Services Task Force Recommendation located?. ### Response: Rockville, MD.


Instruction: When was the report released?

Output: January 5, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the report released?. ### Response: January 5, 2019.


Instruction: What city was the location of the report published?

Output: Rockville, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What city was the location of the report published?. ### Response: Rockville, MD.


Instruction: What did the US Preventive Services Task Force review for cessation in adults, including pregnant women?

Output: Behavioral counsel-ing and pharmacotherapy interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the US Preventive Services Task Force review for cessation in adults, including pregnant women?. ### Response: Behavioral counsel-ing and pharmacotherapy interventions.


Instruction: What was the name of the systematic evidence review of aspirin for the pri-mary prevention of cardiovascular events?

Output: Aspirin for the pri-mary prevention of cardiovascular events: a systematic evidence review for the US Preventive Services Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic evidence review of aspirin for the pri-mary prevention of cardiovascular events?. ### Response: Aspirin for the pri-mary prevention of cardiovascular events: a systematic evidence review for the US Preventive Services Task Force.


Instruction: What is the name of the US Preventive Services Task Force?

Output: Preventive Services Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the US Preventive Services Task Force?. ### Response: Preventive Services Task Force.


Instruction: When was the evidence review for the US PSTTF released?

Output: January 5, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the evidence review for the US PSTTF released?. ### Response: January 5, 2019.


Instruction: What is the 2017 VA/SCD GuidelineCirculation. 2018;138:e272–e391 DOI: 10.1161/CIR.0000000000000549 September 25, 2018 e311CLINICAL STATEMENTS AND GUIDELINESFigure 6. Secondary and primary prevention of what in patients with NICM?

Output: SCD in patients with NICM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 VA/SCD GuidelineCirculation. 2018;138:e272–e391 DOI: 10.1161/CIR.0000000000000549 September 25, 2018 e311CLINICAL STATEMENTS AND GUIDELINESFigure 6. Secondary and primary prevention of what in patients with NICM?. ### Response: SCD in patients with NICM.


Instruction: What indicates secondary?

Output: 2°

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates secondary?. ### Response: 2°.


Instruction: What indicates guideline-directed management and therapy?

Output: GDMT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates guideline-directed management and therapy?. ### Response: GDMT.


Instruction: ICD, what?

Output: meaningful survival greater than 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ICD, what?. ### Response: meaningful survival greater than 1 year.


Instruction: SCA, sudden cardiac arrest, SCD, and VA are examples of what type of disease?

Output: arrhythmogenic right ventricular cardiomyopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: SCA, sudden cardiac arrest, SCD, and VA are examples of what type of disease?. ### Response: arrhythmogenic right ventricular cardiomyopathy.


Instruction: What is the acronym for sudden cardiac death?

Output: SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for sudden cardiac death?. ### Response: SCD.


Instruction: What is a wearable cardioverter-defibrillator?

Output: WCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a wearable cardioverter-defibrillator?. ### Response: WCD.


Instruction: In what study was successful ablation of all VT morphologies achieved in 66.7% of patients?

Output: HELP-VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what study was successful ablation of all VT morphologies achieved in 66.7% of patients?. ### Response: HELP-VT.


Instruction: What was achieved in 66.7% of patients with NICM?

Output: successful ablation of all VT mor -phologies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was achieved in 66.7% of patients with NICM?. ### Response: successful ablation of all VT mor -phologies.


Instruction: What was the suc-cess rate in ischemic cardiomyopathy?

Output: 77.4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the suc-cess rate in ischemic cardiomyopathy?. ### Response: 77.4%.


Instruction: An epi-cardial approach to ablation was required in 30.2% of what patients?

Output: NICM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: An epi-cardial approach to ablation was required in 30.2% of what patients?. ### Response: NICM.


Instruction: Epicardial ablation is an independent predictor of what?

Output: suc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Epicardial ablation is an independent predictor of what?. ### Response: suc.


Instruction: What was an independent predictor of suc-cessful ablation?

Output: Epicardial ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was an independent predictor of suc-cessful ablation?. ### Response: Epicardial ablation.


Instruction: Acute and long-term success of ablation is lower for NICM patients compared with what other type of patient?

Output: post-MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Acute and long-term success of ablation is lower for NICM patients compared with what other type of patient?. ### Response: post-MI.


Instruction: What percentage of VT recurrence after catheter ablation appears to be better for patients with ischemic?

Output: 57%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of VT recurrence after catheter ablation appears to be better for patients with ischemic?. ### Response: 57%.


Instruction: What is the risk of post-MI VT ablation similar to?

Output: epicardial access and ablation when required

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of post-MI VT ablation similar to?. ### Response: epicardial access and ablation when required.


Instruction: What can any NICM produce?

Output: scar-related VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can any NICM produce?. ### Response: scar-related VT.


Instruction: Cardiovascular sarcoidosis and Lamin muta-tions are associated with what?

Output: sustained monomorphic VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cardiovascular sarcoidosis and Lamin muta-tions are associated with what?. ### Response: sustained monomorphic VT.


Instruction: What is particularly associated with sustained monomorphic VT?

Output: cardiac sarcoidosis (see Section 7.6) and Lamin muta-tions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is particularly associated with sustained monomorphic VT?. ### Response: cardiac sarcoidosis (see Section 7.6) and Lamin muta-tions.


Instruction: What is summarized in Online Data Supplement 30.COR LOE Recommendations?

Output: References that support the recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is summarized in Online Data Supplement 30.COR LOE Recommendations?. ### Response: References that support the recommendations.


Instruction: What is recommended for patients with arrhythmogenic right ventricular cardiomyopathy?

Output: an ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with arrhythmogenic right ventricular cardiomyopathy?. ### Response: an ICD.


Instruction: What type of testing is recommended if the proband has a disease causing mutation?

Output: genetic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of testing is recommended if the proband has a disease causing mutation?. ### Response: genetic.


Instruction: What is useful for establishing a diagnosis and for risk stratification?

Output: cardiac MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful for establishing a diagnosis and for risk stratification?. ### Response: cardiac MRI.


Instruction: What is an ICD recommended if meaningful?

Output: survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ICD recommended if meaningful?. ### Response: survival.


Instruction: What is recommended if meaningful survival greater than 1 year is expected?

Output: an ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended if meaningful survival greater than 1 year is expected?. ### Response: an ICD.


Instruction: RVEF or LVEF 35%) is an ICD recommended?

Output: meaningful survival greater than 1 year is expected

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: RVEF or LVEF 35%) is an ICD recommended?. ### Response: meaningful survival greater than 1 year is expected.


Instruction: Anti-anginal drug tr eatmen t Gener al recommenda tions 1.4.1 Offer people optimal drug eatment f or the initial management of what?

Output: stable angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anti-anginal drug tr eatmen t Gener al recommenda tions 1.4.1 Offer people optimal drug eatment f or the initial management of what?. ### Response: stable angina.


Instruction: What is the aim of anti-anginal drug tr eatment to prevent episodes of angina?

Output: t o prevent episodes of angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the aim of anti-anginal drug tr eatment to prevent episodes of angina?. ### Response: t o prevent episodes of angina.


Instruction: What is t he aim of secondar y prevention to prevent car diovascular disease?

Output: Optimal drug tr eatment consist s of one or tw o anti-anginal drugs as necessar y plus drugs f or secondar y prevention of car diovascular disease. 1.4.2 Advise people t hat t he aim of anti-anginal drug tr eatment is t o prevent episodes of angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he aim of secondar y prevention to prevent car diovascular disease?. ### Response: Optimal drug tr eatment consist s of one or tw o anti-anginal drugs as necessar y plus drugs f or secondar y prevention of car diovascular disease. 1.4.2 Advise people t hat t he aim of anti-anginal drug tr eatment is t o prevent episodes of angina.


Instruction: What is t o prevent car diovascular e vents such as hear t attack and str oke?

Output: prevention tr eatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t o prevent car diovascular e vents such as hear t attack and str oke?. ### Response: prevention tr eatment.


Instruction: Discuss ho w side eff ects of what?

Output: drug tr eatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Discuss ho w side eff ects of what?. ### Response: drug tr eatment.


Instruction: What is impor tant t o tak e drug tr eatment regularly?

Output: Discuss ho w side eff ects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is impor tant t o tak e drug tr eatment regularly?. ### Response: Discuss ho w side eff ects.


Instruction: What is patient s diff erence in the type and amount of inf ormation they need and want?

Output: type

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is patient s diff erence in the type and amount of inf ormation they need and want?. ### Response: type.


Instruction: Therefore the pr ovision of what should be individualised?

Output: inf ormation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Therefore the pr ovision of what should be individualised?. ### Response: inf ormation.


Instruction: What should be individualised and include, but not be limit ed to?

Output: inf ormation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be individualised and include, but not be limit ed to?. ### Response: inf ormation.


Instruction: What is lik ely to aff ect t heir condition (that is, it s benefit?

Output: how the medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lik ely to aff ect t heir condition (that is, it s benefit?. ### Response: how the medicine.


Instruction: What are the likely or significant adv erse eff ects and what t hey do if you think you are experiencing them?

Output: how to use t he medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the likely or significant adv erse eff ects and what t hey do if you think you are experiencing them?. ### Response: how to use t he medicine.


Instruction: How to use the medicine?

Output: how to use t he medicine • what t o do if t hey miss a dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How to use the medicine?. ### Response: how to use t he medicine • what t o do if t hey miss a dose.


Instruction: What do hey miss a dose of?

Output: medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do hey miss a dose of?. ### Response: medicine.


Instruction: What is t he NICE guideline on medicines adherence?

Output: 1.4.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he NICE guideline on medicines adherence?. ### Response: 1.4.5.


Instruction: What should a patient do if she misses a dose of a medicine?

Output: what t o do if t hey miss a dose • whet her fur ther courses of t he medicine will be needed aft er the first prescription • how to get fur ther supplies of medicines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient do if she misses a dose of a medicine?. ### Response: what t o do if t hey miss a dose • whet her fur ther courses of t he medicine will be needed aft er the first prescription • how to get fur ther supplies of medicines.


Instruction: What is the name of the guideline on medicines adherence?

Output: NICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline on medicines adherence?. ### Response: NICE.


Instruction: How many weeks to review a person's r esponse t o treatment?

Output: 2 to 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many weeks to review a person's r esponse t o treatment?. ### Response: 2 to 4.


Instruction: Stable angina: management (CG126) NICE 2022.

Output: how to use t he medicine • what t o do if t hey miss a dose • whet her fur ther courses of t he medicine will be needed aft er the first prescription • how to get fur ther supplies of medicines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stable angina: management (CG126) NICE 2022.. ### Response: how to use t he medicine • what t o do if t hey miss a dose • whet her fur ther courses of t he medicine will be needed aft er the first prescription • how to get fur ther supplies of medicines.


Instruction: What year is NICE 2022. All right s reserved?

Output: Stable angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year is NICE 2022. All right s reserved?. ### Response: Stable angina.


Instruction: What is the last updat ed 25 August 2016?

Output: Page 12of 26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 25 August 2016?. ### Response: Page 12of 26.


Instruction: Powers and al 2019 Guidelines for Management of AIS e3552. Emergency Evaluation and Treatment2.1. Stroke Scales COR LOE New, Revised, or Unchanged1. The use of a stroke severity rating scale, preferably the NIHSS, is recommended.

Output: 75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Powers and al 2019 Guidelines for Management of AIS e3552. Emergency Evaluation and Treatment2.1. Stroke Scales COR LOE New, Revised, or Unchanged1. The use of a stroke severity rating scale, preferably the NIHSS, is recommended.. ### Response: 75.


Instruction: B-NRRecommendation reworded for clarity from 2013 AIS Guidelines.

Output: stroke severity rating scale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: B-NRRecommendation reworded for clarity from 2013 AIS Guidelines.. ### Response: stroke severity rating scale.


Instruction: COR unchanged.

Output: LOE amended to conform with ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: COR unchanged.. ### Response: LOE amended to conform with ACC/AHA 2015 Recommendation Classification System.


Instruction: LOE amended to conform with what?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LOE amended to conform with what?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: What can be performed quickly, have demonstrated utility, and be administered by a broad spectrum of healthcare providers with accuracy and reliability?

Output: Table 4)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be performed quickly, have demonstrated utility, and be administered by a broad spectrum of healthcare providers with accuracy and reliability?. ### Response: Table 4).


Instruction: Use of a standardized scale quantifies the degree of neurological deficit, facilitates communication, helps identify patients for what?

Output: fibrinolytic or mechanical intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Use of a standardized scale quantifies the degree of neurological deficit, facilitates communication, helps identify patients for what?. ### Response: fibrinolytic or mechanical intervention.


Instruction: What type of intervention allows objective measurement of changing clinical status and identifies those at higher risk for complications such as intracerebral hemorrhage?

Output: fibrinolytic or mechanical intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention allows objective measurement of changing clinical status and identifies those at higher risk for complications such as intracerebral hemorrhage?. ### Response: fibrinolytic or mechanical intervention.


Instruction: What is a Level of consciousness0?

Output: —Alert

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Level of consciousness0?. ### Response: —Alert.


Instruction: What is an alert 1?

Output: 1—Drowsy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an alert 1?. ### Response: 1—Drowsy.


Instruction: What is the difference between partial and complete gaze palsy?

Output: Visual fields 0—No visual field defect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between partial and complete gaze palsy?. ### Response: Visual fields 0—No visual field defect.


Instruction: What are the differences between partial hemianopia 2 and complete eyepalsy 3?

Output: Visual fields 0—No visual field defect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between partial hemianopia 2 and complete eyepalsy 3?. ### Response: Visual fields 0—No visual field defect.


Instruction: Before 10 sb. Right 2—Falls before what s 3—No effort against gravity 4—No movement6 Motor function (leg) 0—No drift a. Left 1—Drift before how many seconds?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Before 10 sb. Right 2—Falls before what s 3—No effort against gravity 4—No movement6 Motor function (leg) 0—No drift a. Left 1—Drift before how many seconds?. ### Response: 10.


Instruction: How many limbs are affected by ataxia?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many limbs are affected by ataxia?. ### Response: 2.


Instruction: What type of loss is present in 1 limb?

Output: Ataxia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of loss is present in 1 limb?. ### Response: Ataxia.


Instruction: In what limb is there no loss of sensory information?

Output: Sensory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what limb is there no loss of sensory information?. ### Response: Sensory.


Instruction: Inattention0—Absent 1—Mild loss (1 sensory modality lost) 2—Severe loss (2 modalities lost)Adapted from Lyden et al.74 Copyright  1994, American Heart Association, Inc.Table 4. ContinuedTested Item Title Responses and ScoresDownloaded by on what date?

Output: Extinction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inattention0—Absent 1—Mild loss (1 sensory modality lost) 2—Severe loss (2 modalities lost)Adapted from Lyden et al.74 Copyright  1994, American Heart Association, Inc.Table 4. ContinuedTested Item Title Responses and ScoresDownloaded by on what date?. ### Response: Extinction.


Instruction: What type of therapy is recommended in patients with low-risk PE and whose homecircumstances are adequate?

Output: Systemic Thrombolytic Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is recommended in patients with low-risk PE and whose homecircumstances are adequate?. ### Response: Systemic Thrombolytic Therapy.


Instruction: In patients with acute PE associated withhypotension, what type of thrombolytic therapy is suggested?

Output: systemicallyadministered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with acute PE associated withhypotension, what type of thrombolytic therapy is suggested?. ### Response: systemicallyadministered.


Instruction: What is recommended in patients with acute PE associated withhypotension who do not have a high bleeding risk?

Output: systemicallyadministered thrombolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with acute PE associated withhypotension who do not have a high bleeding risk?. ### Response: systemicallyadministered thrombolytic therapy.


Instruction: What is the grade of thrombolytic therapy that is recommended over no such therapy?

Output: Grade 2C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the grade of thrombolytic therapy that is recommended over no such therapy?. ### Response: Grade 2C.


Instruction: In most patients who have acute PE not associated with hypotension, we recommend against what?

Output: systemically administered thrombolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In most patients who have acute PE not associated with hypotension, we recommend against what?. ### Response: systemically administered thrombolytic therapy.