Instruction: All right s reserved.

Output: Recent -onset chest pain of suspect ed car diac origin: assessment and diagnosis (CG95)© NICE 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: All right s reserved.. ### Response: Recent -onset chest pain of suspect ed car diac origin: assessment and diagnosis (CG95)© NICE 2022.


Instruction: Last updat ed 30 No vember 2016.

Output: 33of 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Last updat ed 30 No vember 2016.. ### Response: 33of 33.


Instruction: What are the best data for the use of VKA in the TEE-guided approach?

Output: Assessment ofCardioversion Using TransesophagealEchocardiography (ACUTE) RCT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the best data for the use of VKA in the TEE-guided approach?. ### Response: Assessment ofCardioversion Using TransesophagealEchocardiography (ACUTE) RCT.


Instruction: What is the name of the RCT that compares abbreviated therapeuticanticoagulation with IV UFH?

Output: Assessment ofCardioversion Using TransesophagealEchocardiography (ACUTE)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the RCT that compares abbreviated therapeuticanticoagulation with IV UFH?. ### Response: Assessment ofCardioversion Using TransesophagealEchocardiography (ACUTE).


Instruction: How long before cardioversion is the TEE-guided strategy?

Output: 3 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before cardioversion is the TEE-guided strategy?. ### Response: 3 weeks.


Instruction: What is the conventional approach of 3 weeks of anticoagulationpre-cardioversion?

Output: TEE-guided strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the conventional approach of 3 weeks of anticoagulationpre-cardioversion?. ### Response: TEE-guided strategy.


Instruction: How long was the anticoagulation pre-cardioversion?

Output: 3 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the anticoagulation pre-cardioversion?. ### Response: 3 weeks.


Instruction: What was the relative RR for stroke/thromboembolism for NOACs vs warfarin in the TEE-guided approach?

Output: 0.33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the relative RR for stroke/thromboembolism for NOACs vs warfarin in the TEE-guided approach?. ### Response: 0.33.


Instruction: What was the CI for NOACs vs warfarin?

Output: 0.06-1.68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the CI for NOACs vs warfarin?. ### Response: 0.06-1.68.


Instruction: What is the advantage of noACs?

Output: their modeof action is quicker than VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the advantage of noACs?. ### Response: their modeof action is quicker than VKA.


Instruction: Why is the evidence of NOAC low quality?

Output: no bridging therapynecessary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the evidence of NOAC low quality?. ### Response: no bridging therapynecessary.


Instruction: What is the advantage of NOACs?

Output: their modeof action is quicker than VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the advantage of NOACs?. ### Response: their modeof action is quicker than VKA.


Instruction: Why is there no delay in waiting for a therapeutic INR?

Output: no bridging therapynecessary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there no delay in waiting for a therapeutic INR?. ### Response: no bridging therapynecessary.


Instruction: What must be stressed to patients in the post-cardioversion period?

Output: strict adherence to the NOAC therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be stressed to patients in the post-cardioversion period?. ### Response: strict adherence to the NOAC therapy.


Instruction: What can be expedited by a thrombus-negative TEE?

Output: cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be expedited by a thrombus-negative TEE?. ### Response: cardioversion.


Instruction: A TEE-guided approach can be used to avoid what?

Output: prolonged VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A TEE-guided approach can be used to avoid what?. ### Response: prolonged VKA.


Instruction: What is a particular consideration in patients at increased risk for bleeding?

Output: a TEE-guided approach canbe used to avoid prolonged VKA before cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a particular consideration in patients at increased risk for bleeding?. ### Response: a TEE-guided approach canbe used to avoid prolonged VKA before cardioversion.


Instruction: What offer analternative to prolonged anticoagulation beforecardioversion?

Output: NOACs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What offer analternative to prolonged anticoagulation beforecardioversion?. ### Response: NOACs.


Instruction: A “risk-based approach”toanticoagulation should be used what?

Output: outpatient setting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A “risk-based approach”toanticoagulation should be used what?. ### Response: outpatient setting.


Instruction: What is the low risk of recurrent AF?

Output: stroke risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the low risk of recurrent AF?. ### Response: stroke risk factors.


Instruction: What should be started at the time of TEE andcardioversion performed within 24 hours?

Output: IV UFH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be started at the time of TEE andcardioversion performed within 24 hours?. ### Response: IV UFH.


Instruction: What is performed within 24 h of the TEE if nothrombus is seen?

Output: cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed within 24 h of the TEE if nothrombus is seen?. ### Response: cardioversion.


Instruction: What has similar ef ficacy compared with heparinor warfarin for immediate anticoagulation beforeTEE?

Output: LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has similar ef ficacy compared with heparinor warfarin for immediate anticoagulation beforeTEE?. ### Response: LMWH.


Instruction: What should a TEE-guided approach involve initiation of?

Output: VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a TEE-guided approach involve initiation of?. ### Response: VKA.


Instruction: What should be scheduled 5 days later if the INR is intherapeutic range at that time?

Output: cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be scheduled 5 days later if the INR is intherapeutic range at that time?. ### Response: cardioversion.


Instruction: NOACs offer an alternative in outpatient treatment before what?

Output: TEE-guided cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: NOACs offer an alternative in outpatient treatment before what?. ### Response: TEE-guided cardioversion.


Instruction: What are the determinants of the outcome of asymptomatic mitral regurgitation?

Output: Quantitative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the determinants of the outcome of asymptomatic mitral regurgitation?. ### Response: Quantitative.


Instruction: What is the N Engl J Med. 2005:352:875-83?

Output: Quantitative determinants of the outcome of asymptomatic mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2005:352:875-83?. ### Response: Quantitative determinants of the outcome of asymptomatic mitral regurgitation.


Instruction: Who is the Outcome of watchful waiting in?

Output: as-ymptomatic severe mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Outcome of watchful waiting in?. ### Response: as-ymptomatic severe mitral regurgitation.


Instruction: What is the name of the multicenter European study that investigated mitral regurgita-tion due to flail leaflets?

Output: JACC Cardiovasc Imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter European study that investigated mitral regurgita-tion due to flail leaflets?. ### Response: JACC Cardiovasc Imaging.


Instruction: What is a propensity analysis of early surgery versus conventional treat-ment for?

Output: asymptomatic severe mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a propensity analysis of early surgery versus conventional treat-ment for?. ### Response: asymptomatic severe mitral regurgitation.


Instruction: What is a propensity analysis of conventional treatment for asymptomatic severe mitral regurgitation?

Output: Early surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a propensity analysis of conventional treatment for asymptomatic severe mitral regurgitation?. ### Response: Early surgery.


Instruction: What is Rosen SE, Borer JS, Hochreiter C, et al.?

Output: Natural history of the asymp-tomatic/minimally symptomatic patient with severe mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Rosen SE, Borer JS, Hochreiter C, et al.?. ### Response: Natural history of the asymp-tomatic/minimally symptomatic patient with severe mitral regurgitation.


Instruction: What is the difference between echocardiog-raphy and normal right and left ventricular performance?

Output: mitral valve prolapse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between echocardiog-raphy and normal right and left ventricular performance?. ### Response: mitral valve prolapse.


Instruction: When was the Am J Cardiol.74:374–80 published?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol.74:374–80 published?. ### Response: 1994.


Instruction: What is a clinical competence statement on echocardiology?

Output: a report of the American College of Cardiology/American Heart As-sociation/American College of Physicians—American Society of Internal Medicine Task Force on Clinical Competence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a clinical competence statement on echocardiology?. ### Response: a report of the American College of Cardiology/American Heart As-sociation/American College of Physicians—American Society of Internal Medicine Task Force on Clinical Competence.


Instruction: As-sociation/American College of Physicians—American Society of Internal Medicine Task Force on Clinical Competency.

Output: American College of Cardiology/American Heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: As-sociation/American College of Physicians—American Society of Internal Medicine Task Force on Clinical Competency.. ### Response: American College of Cardiology/American Heart.


Instruction: In collaboration with the American Society of Echocardiography, the Society of Cardiovascular Anesthesiologists, and the Societee of Pediatric Echocardigraphy, what task force was developed?

Output: American Society of Internal Medicine Task Force on Clinical Competence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In collaboration with the American Society of Echocardiography, the Society of Cardiovascular Anesthesiologists, and the Societee of Pediatric Echocardigraphy, what task force was developed?. ### Response: American Society of Internal Medicine Task Force on Clinical Competence.


Instruction: Circulation. 2003;107:1068-89.

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2003;107:1068-89.. ### Response: 12.


Instruction: What is B-type natriuretic pep-tide in organic mitral regurgitation?

Output: determinants and impact on outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is B-type natriuretic pep-tide in organic mitral regurgitation?. ### Response: determinants and impact on outcome.


Instruction: What is the name of the journal that studies the impact on outcome of mitral recurrence?

Output: JACC Cardiovasc Imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the impact on outcome of mitral recurrence?. ### Response: JACC Cardiovasc Imaging.


Instruction: How do plasma levels of natruretic peptide levels increase with symptoms and severity?

Output: mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do plasma levels of natruretic peptide levels increase with symptoms and severity?. ### Response: mitral regurgitation.


Instruction: What is the name of the study that evaluated the prognostic value of brain natriuretic peptide in asymptomatic patients with chronic severe mitral regurgitation?

Output: Prospective validation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the prognostic value of brain natriuretic peptide in asymptomatic patients with chronic severe mitral regurgitation?. ### Response: Prospective validation.


Instruction: When was the J Am Coll Cardiol.54:1099-106 published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol.54:1099-106 published?. ### Response: 2009.


Instruction: What is the synergistic utility of brain natriuretic peptide and left ventricular global longitudinal strain in asymptomatic patients with significant primary mitral regurgitation and preserved sys-tolic functionundergoing mitral valve surgery?

Output: Prospective validation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the synergistic utility of brain natriuretic peptide and left ventricular global longitudinal strain in asymptomatic patients with significant primary mitral regurgitation and preserved sys-tolic functionundergoing mitral valve surgery?. ### Response: Prospective validation.


Instruction: What is the prognostic value of serial B-type natriuretic peptide measurement in asymptomatic organic mitral regurgitation?

Output: impact on outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic value of serial B-type natriuretic peptide measurement in asymptomatic organic mitral regurgitation?. ### Response: impact on outcome.


Instruction: Eur J Heart Fail. 2011;13:163-9.

Output: 17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Eur J Heart Fail. 2011;13:163-9.. ### Response: 17.


Instruction: Mentias A, Patel K, and Patel H use what?

Output: brain natri-uretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Mentias A, Patel K, and Patel H use what?. ### Response: brain natri-uretic peptide.


Instruction: What are asymptomatic patients with significant mitral regur -gitation and preserved left ventricular ejection fraction?

Output: brain natri-uretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are asymptomatic patients with significant mitral regur -gitation and preserved left ventricular ejection fraction?. ### Response: brain natri-uretic peptide.


Instruction: What is the name of the journal that studies the prognostic importance of brain na-tion?

Output: Am J Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the prognostic importance of brain na-tion?. ### Response: Am J Cardiol.


Instruction: What type of oxygen therapy is recommended for people with advanced heart failure?

Output: Domiciliary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of oxygen therapy is recommended for people with advanced heart failure?. ### Response: Domiciliary.


Instruction: What is the name of the drug used to treat chronic heart failure in adults?

Output: Domiciliary oxygen therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat chronic heart failure in adults?. ### Response: Domiciliary oxygen therapy.


Instruction: Who did the committee recommend that the patient be told at their next consultation?

Output: a member of the specialist heart failure multi disciplinary team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who did the committee recommend that the patient be told at their next consultation?. ### Response: a member of the specialist heart failure multi disciplinary team.


Instruction: Who did the committee discuss the importance of having involved in communication from an early stage?

Output: family members/carers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who did the committee discuss the importance of having involved in communication from an early stage?. ### Response: family members/carers.


Instruction: What can be overwhelming for a patient when they receive bad news in the form of a diagnosis of heart failure?

Output: family members/carers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be overwhelming for a patient when they receive bad news in the form of a diagnosis of heart failure?. ### Response: family members/carers.


Instruction: Carers may be better able to take on board information regarding what?

Output: ongoing care and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Carers may be better able to take on board information regarding what?. ### Response: ongoing care and management.


Instruction: How do family members and carers help when a patient has conveyed information poorly or partially to them?

Output: inclusion of a family member or carer in one or more consultations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do family members and carers help when a patient has conveyed information poorly or partially to them?. ### Response: inclusion of a family member or carer in one or more consultations.


Instruction: A family member or carer may struggle with how best to help when the patient conveys information poorly to whom?

Output: them

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A family member or carer may struggle with how best to help when the patient conveys information poorly to whom?. ### Response: them.


Instruction: The inclusion of a family member or carer in one or more consultations will improve what?

Output: the understanding of the condition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The inclusion of a family member or carer in one or more consultations will improve what?. ### Response: the understanding of the condition.


Instruction: The committee acknowledged that this was covered by which guideline?

Output: patient experience guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee acknowledged that this was covered by which guideline?. ### Response: patient experience guideline.


Instruction: What section agreed to include a cross-cultural consultation?

Output: section 1.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section agreed to include a cross-cultural consultation?. ### Response: section 1.3.


Instruction: What should be communicated to the patient in the first 2 appointments with the heart failure MDT?

Output: what they can expect to happen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be communicated to the patient in the first 2 appointments with the heart failure MDT?. ### Response: what they can expect to happen.


Instruction: What does MDT stand for?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MDT stand for?. ### Response: heart failure.


Instruction: What are some examples of proscriptions for heart failure?

Output: dietary, physical activities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some examples of proscriptions for heart failure?. ### Response: dietary, physical activities.


Instruction: What do cardiologists often have to dispel at the first consultation with a newly diagnosed patient?

Output: misconceived ideas

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do cardiologists often have to dispel at the first consultation with a newly diagnosed patient?. ### Response: misconceived ideas.


Instruction: What may result from misunderstandings occurring when patients are referred for specialist investigation of heart disease?

Output: family members and carers often struggle with  how best to help when the patient has conveyed information poorly or partially to them

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may result from misunderstandings occurring when patients are referred for specialist investigation of heart disease?. ### Response: family members and carers often struggle with  how best to help when the patient has conveyed information poorly or partially to them.


Instruction: When are patients referred for specialist investigation of heart failure symptoms?

Output: next consultation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When are patients referred for specialist investigation of heart failure symptoms?. ### Response: next consultation.


Instruction: The committee was aware of a lack of public awareness of what?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee was aware of a lack of public awareness of what?. ### Response: heart failure.


Instruction: What did the committee not support?

Output: the use of euphemisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee not support?. ### Response: the use of euphemisms.


Instruction: What should health care professionals use the term heart failure in an open and honest manner with the patient?

Output: explaining its meaning in detail, dispelling any myths or other fears induc ed by the language, and providing a balanced picture of the condition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should health care professionals use the term heart failure in an open and honest manner with the patient?. ### Response: explaining its meaning in detail, dispelling any myths or other fears induc ed by the language, and providing a balanced picture of the condition.


Instruction: What does the word heart failure explain in detail?

Output: its meaning

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the word heart failure explain in detail?. ### Response: its meaning.


Instruction: What did the committee discuss to avoid confusion for patients?

Output: practice some phrases to explain the condition before seeing the patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee discuss to avoid confusion for patients?. ### Response: practice some phrases to explain the condition before seeing the patient.


Instruction: What could be used to explain heart failure?

Output: phrases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be used to explain heart failure?. ### Response: phrases.


Instruction: What could professionals practice to explain the condition before seeing the patient?

Output: phrases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could professionals practice to explain the condition before seeing the patient?. ### Response: phrases.


Instruction: What should discussion of prognosis be?

Output: a gradual process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should discussion of prognosis be?. ### Response: a gradual process.


Instruction: What is the name of the book that describes the treatment of chronic heart failure?

Output: 223 7.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes the treatment of chronic heart failure?. ### Response: 223 7.1.


Instruction: What type of rehabilitation can be used?

Output: Home -based versus centre -based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of rehabilitation can be used?. ### Response: Home -based versus centre -based.


Instruction: What is the difference between home based and centre based rehabilitation for people with heart failure?

Output: clinical and cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between home based and centre based rehabilitation for people with heart failure?. ### Response: clinical and cost effectiveness.


Instruction: What is heart failure?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heart failure?. ### Response: HF.


Instruction: What is economic evidence?

Output: Evidence statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is economic evidence?. ### Response: Evidence statements.


Instruction: What type of monitoring is used for management of chronic heart failure?

Output: biomarker -based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of monitoring is used for management of chronic heart failure?. ### Response: biomarker -based.


Instruction: What is 233 8.1.1 Introduction?

Output: Monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 233 8.1.1 Introduction?. ### Response: Monitoring.


Instruction: What is the clinical and cost effectiveness of biomarker based monitoring?

Output: 238 8.1.2  Review question: What is the clinical and cost effectiveness of biomarker -based monitoring, monitoring with cardiac MRI, and m onitoring with repeated echocardiography in people with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical and cost effectiveness of biomarker based monitoring?. ### Response: 238 8.1.2  Review question: What is the clinical and cost effectiveness of biomarker -based monitoring, monitoring with cardiac MRI, and m onitoring with repeated echocardiography in people with heart failure.


Instruction: What is monitoring with cardiac MRI and repeated echocardiography in people with heart failure?

Output: biomarker -based monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is monitoring with cardiac MRI and repeated echocardiography in people with heart failure?. ### Response: biomarker -based monitoring.


Instruction: In people with heart failure?

Output: clinical and cost effectiveness of home -based versus centre -based rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In people with heart failure?. ### Response: clinical and cost effectiveness of home -based versus centre -based rehabilitation.


Instruction: What is used to monitor for management of chronic pain?

Output: repeated biomarker measurement or imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to monitor for management of chronic pain?. ### Response: repeated biomarker measurement or imaging.


Instruction: How does economic evidence compare to clinical evidence?

Output: 252

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does economic evidence compare to clinical evidence?. ### Response: 252.


Instruction: What is used for management of chronic heart failure in people who also have chronic kidney disease?

Output: repeated biomarker measurement or imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used for management of chronic heart failure in people who also have chronic kidney disease?. ### Response: repeated biomarker measurement or imaging.


Instruction: What is monitoring with cardiac MRI?

Output: biomarker -based monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is monitoring with cardiac MRI?. ### Response: biomarker -based monitoring.


Instruction: How many studies have reported that women have higher case fatality than men?

Output: 26 of 31

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have reported that women have higher case fatality than men?. ### Response: 26 of 31.


Instruction: What did a recent systematic review find that short-term case death was higher in women than men in 26 of 31 studies?

Output: 24.7% versus 19.7%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a recent systematic review find that short-term case death was higher in women than men in 26 of 31 studies?. ### Response: 24.7% versus 19.7%),.


Instruction: What percentage of stroke deaths were based on crude unadjusted data?

Output: 26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of stroke deaths were based on crude unadjusted data?. ### Response: 26.


Instruction: What is likely to be attributable to the fact that women tend to be older at the time of their stroke?

Output: higher case fatality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to be attributable to the fact that women tend to be older at the time of their stroke?. ### Response: higher case fatality.


Instruction: What do studies that have adjusted for age show?

Output: the sex difference in short-term mortality can actually reverse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do studies that have adjusted for age show?. ### Response: the sex difference in short-term mortality can actually reverse.


Instruction: What does the sex difference in short-term mortality actually reverse?

Output: lower mortality after adjustment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the sex difference in short-term mortality actually reverse?. ### Response: lower mortality after adjustment.


Instruction: Women have lower mortality after what?

Output: adjustment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Women have lower mortality after what?. ### Response: adjustment.


Instruction: A study of temporal trends (1950-2004) in the US Framingham Study found that age-adjusted 30-day fatality decreased sig-nificantly for men?

Output: 22

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A study of temporal trends (1950-2004) in the US Framingham Study found that age-adjusted 30-day fatality decreased sig-nificantly for men?. ### Response: 22.


Instruction: How much did age-adjusted 30-day fatality decrease for women?

Output: 3.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did age-adjusted 30-day fatality decrease for women?. ### Response: 3.5%.


Instruction: Non-US populations have reported mixed results in terms of what?

Output: sex differences in stroke case fatality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Non-US populations have reported mixed results in terms of what?. ### Response: sex differences in stroke case fatality.


Instruction: What may be attributable to differences in time periods studied?

Output: sex differences in stroke case fatality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be attributable to differences in time periods studied?. ### Response: sex differences in stroke case fatality.


Instruction: What has shown no sex differences or higher rates in men?

Output: Case-fatality studies for IS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has shown no sex differences or higher rates in men?. ### Response: Case-fatality studies for IS.


Instruction: Where did a study examine trends in IS 30-day case fatality?

Output: the Netherlands

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did a study examine trends in IS 30-day case fatality?. ### Response: the Netherlands.


Instruction: What was the largest decline for men in the 65- to 74-year-old age group?

Output: 12.5% to 6.9%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the largest decline for men in the 65- to 74-year-old age group?. ### Response: 12.5% to 6.9%.


Instruction: The largest decline in women was from 6.4% to 3.5% in the 35- to 64-year old age group.

Output: 66

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The largest decline in women was from 6.4% to 3.5% in the 35- to 64-year old age group.. ### Response: 66.


Instruction: What was the percentage of women in the 35- to 64-year-old age group?

Output: 3.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the percentage of women in the 35- to 64-year-old age group?. ### Response: 3.5%.


Instruction: What are the data limited to assess for hemorrhagic strokes?

Output: case fatality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the data limited to assess for hemorrhagic strokes?. ### Response: case fatality.


Instruction: A study restricted to a younger popu-lation reported lower 30-day case fatality after SAH in women than in men?

Output: 9% versus 17%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A study restricted to a younger popu-lation reported lower 30-day case fatality after SAH in women than in men?. ### Response: 9% versus 17%)..


Instruction: What percentage of ICH case fatality in women is lower than in men?

Output: 3.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of ICH case fatality in women is lower than in men?. ### Response: 3.5%.


Instruction: What is the Atherosclerosis Risk in Communities study called?

Output: ARIC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Atherosclerosis Risk in Communities study called?. ### Response: ARIC.


Instruction: How long did the ARIC study report a lower ICH fatality for women than for males?

Output: 30.4% versus 34.5%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the ARIC study report a lower ICH fatality for women than for males?. ### Response: 30.4% versus 34.5%),.


Instruction: How much higher was the 1-month fatality rate for women than men?

Output: 40% versus 35%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was the 1-month fatality rate for women than men?. ### Response: 40% versus 35%)..


Instruction: What was the rate of fatalities for men and women in the Northern Manhattan Stroke Study?

Output: 40% versus 35%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the rate of fatalities for men and women in the Northern Manhattan Stroke Study?. ### Response: 40% versus 35%)..


Instruction: In what year were the US stroke mortality rates for women in 2009?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year were the US stroke mortality rates for women in 2009?. ### Response: 2009.


Instruction: What was the mortality rate for women in 2009?

Output: US stroke mortality rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mortality rate for women in 2009?. ### Response: US stroke mortality rates.


Instruction: What indicates American Indian?

Output: Am Indian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates American Indian?. ### Response: Am Indian.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the date of publication of the 2021 Circulation. 2021:e72–e227?

Output: February 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the date of publication of the 2021 Circulation. 2021:e72–e227?. ### Response: February 2.


Instruction: Where are studies that support the recommendations summarized?

Output: Online Data Supplement 47.COR LOE Recommendations2a B-R1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are studies that support the recommendations summarized?. ### Response: Online Data Supplement 47.COR LOE Recommendations2a B-R1.


Instruction: In asymptomatic patients with moderate or greater degrees of AS and normal LV systolic function, it is reasonable to perform what?

Output: elective noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In asymptomatic patients with moderate or greater degrees of AS and normal LV systolic function, it is reasonable to perform what?. ### Response: elective noncardiac surgery.


Instruction: What is it reasonable to perform in asymptomatic patients with moderate or greater degrees of rheumatic MS with less than severe pulmonary hypertension?

Output: elective noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is it reasonable to perform in asymptomatic patients with moderate or greater degrees of rheumatic MS with less than severe pulmonary hypertension?. ### Response: elective noncardiac surgery.


Instruction: What is the pulmonary artery systolic pressure 50mm Hg?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pulmonary artery systolic pressure 50mm Hg?. ### Response: <.


Instruction: What is the pulmonary artery systolic pressure 50 mm Hg?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pulmonary artery systolic pressure 50 mm Hg?. ### Response: <.


Instruction: In asymptomatic patients with moderate or greater degrees of AR and normal LV function, it is reasonable to perform what?

Output: elective noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In asymptomatic patients with moderate or greater degrees of AR and normal LV function, it is reasonable to perform what?. ### Response: elective noncardiac surgery.


Instruction: What is the risk associated with noncardiac surgery in asymptomatic patients with significant VHD?

Output: do not meet standard criteria for intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk associated with noncardiac surgery in asymptomatic patients with significant VHD?. ### Response: do not meet standard criteria for intervention.


Instruction: What is ap-propriate to the anesthetic approach?

Output: valve lesion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ap-propriate to the anesthetic approach?. ### Response: valve lesion.


Instruction: What is an anesthetic approach that is ap-propriate to the valve lesion and ensuring a higher level of intraoperative monitoring?

Output: prophylactic AVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an anesthetic approach that is ap-propriate to the valve lesion and ensuring a higher level of intraoperative monitoring?. ### Response: prophylactic AVR.


Instruction: What is the underlying valvular abnormality, its ef-fect on LV function and comorbidities?

Output: intraoperative (and perioperative) monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the underlying valvular abnormality, its ef-fect on LV function and comorbidities?. ### Response: intraoperative (and perioperative) monitoring.


Instruction: In patients with VHD, the cardiovascular risk of noncardiac surgery is also impacted by what?

Output: Regurgitant lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with VHD, the cardiovascular risk of noncardiac surgery is also impacted by what?. ### Response: Regurgitant lesions.


Instruction: What is the risk of noncardiac surgery impacted by?

Output: Regurgitant lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of noncardiac surgery impacted by?. ### Response: Regurgitant lesions.


Instruction: What are some other cardiovascular conditions?

Output: LV and RV dysfunction, CAD, pulmonary hyperten-sion, and peripheral artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some other cardiovascular conditions?. ### Response: LV and RV dysfunction, CAD, pulmonary hyperten-sion, and peripheral artery disease.


Instruction: In patients with moderate or greater degrees of AS, the hemodynamic effects of anesthesia and surgery are poorly tolerated?

Output: intraoperative (and perioperative) monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with moderate or greater degrees of AS, the hemodynamic effects of anesthesia and surgery are poorly tolerated?. ### Response: intraoperative (and perioperative) monitoring.


Instruction: What are the predictors of adverse outcomes?

Output: severity of AS, coexisting MR, pulmonary hypertension, and CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the predictors of adverse outcomes?. ### Response: severity of AS, coexisting MR, pulmonary hypertension, and CAD.


Instruction: What increase the risk of AVR?

Output: bidities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increase the risk of AVR?. ### Response: bidities.


Instruction: The risk-benefit ratio con-tinues to favor managing what?

Output: asymptomatic patients with severe AS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The risk-benefit ratio con-tinues to favor managing what?. ### Response: asymptomatic patients with severe AS.


Instruction: Patients with severe AS are undergoing noncardiac surgery with hemodynamic monitoring and what else?

Output: optimization of load-ing conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with severe AS are undergoing noncardiac surgery with hemodynamic monitoring and what else?. ### Response: optimization of load-ing conditions.


Instruction: What is the patient with rheumatic MS treated in a manner similar to?

Output: the patient with AS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the patient with rheumatic MS treated in a manner similar to?. ### Response: the patient with AS.


Instruction: Regurgitant lesions convey an increased risk of what?

Output: cardiac complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Regurgitant lesions convey an increased risk of what?. ### Response: cardiac complications.


Instruction: What type of lesions carry an increased risk of cardiac complications in patients undergoing noncardiac surgery?

Output: Regurgitant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of lesions carry an increased risk of cardiac complications in patients undergoing noncardiac surgery?. ### Response: Regurgitant.


Instruction: What do regurgitant lesions require careful evaluation and hemodynamic monitoring?

Output: increased risk of cardiac complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do regurgitant lesions require careful evaluation and hemodynamic monitoring?. ### Response: increased risk of cardiac complications.


Instruction: Patients with severe AS and a normal LVEF can undergo what?

Output: noncardiac sur

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with severe AS and a normal LVEF can undergo what?. ### Response: noncardiac sur.


Instruction: What was the name of the study that compared usual care and home telemonitoring?

Output: TM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that compared usual care and home telemonitoring?. ### Response: TM.


Instruction: What were the critical outcomes for decision -making?

Output: all-cause mortality and all -cause hospitalisation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the critical outcomes for decision -making?. ### Response: all-cause mortality and all -cause hospitalisation.


Instruction: What was the critical outcome for decision making?

Output: all-cause mortality and all -cause hospitalisation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the critical outcome for decision making?. ### Response: all-cause mortality and all -cause hospitalisation.


Instruction: How many studies were included in the structured telephone support and telemonitoring review?

Output: Forty -six

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included in the structured telephone support and telemonitoring review?. ### Response: Forty -six.


Instruction: What was the quality of the evidence ranged from?

Output: very low to high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence ranged from?. ### Response: very low to high.


Instruction: What was the range of quality of the evidence?

Output: very low to high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the range of quality of the evidence?. ### Response: very low to high.


Instruction: Why were studies downgraded?

Output: risk of bias or imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were studies downgraded?. ### Response: risk of bias or imprecision.


Instruction: What was not commonly reported by the studies?

Output: adherence to the intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not commonly reported by the studies?. ### Response: adherence to the intervention.


Instruction: What did the authors of the Cochrane review construct to assess for reporting bias within the studies included in the review?

Output: funnel plots

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the authors of the Cochrane review construct to assess for reporting bias within the studies included in the review?. ### Response: funnel plots.


Instruction: What was taken into consideration when assessing the quality of the evidence for outcomes in strata which contained more than 5 studies?

Output: funnel plots

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was taken into consideration when assessing the quality of the evidence for outcomes in strata which contained more than 5 studies?. ### Response: funnel plots.


Instruction: How many studies were there in the funnel plots?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were there in the funnel plots?. ### Response: 5.


Instruction: What did the funnel graphs show?

Output: a strong publication bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the funnel graphs show?. ### Response: a strong publication bias.


Instruction: How was the statistical heterogeneity in the results reported by studies explained?

Output: This was not explained by subgrouping the results by age, year of publication or the intensity of the intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the statistical heterogeneity in the results reported by studies explained?. ### Response: This was not explained by subgrouping the results by age, year of publication or the intensity of the intervention.


Instruction: What is the trade-off between clinical benefits and harms?

Output: Overview of evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the trade-off between clinical benefits and harms?. ### Response: Overview of evidence.


Instruction: The committee noted the likely publication bias in the evidence identified.

Output: adherence to the intervention was not commonly reported by the studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee noted the likely publication bias in the evidence identified.. ### Response: adherence to the intervention was not commonly reported by the studies.


Instruction: What did the committee request?

Output: inclusion of all studies in the review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee request?. ### Response: inclusion of all studies in the review.


Instruction: What did the committee consider likely to be an issue in the evidence?

Output: publication bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee consider likely to be an issue in the evidence?. ### Response: publication bias.


Instruction: What would enable publication bias to be more clearly identified?

Output: funnel plots

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would enable publication bias to be more clearly identified?. ### Response: funnel plots.


Instruction: What did the committee want to be more clearly identified?

Output: publication bias would be an issue in the evidence and that a more comprehensive search strategy not limited to larger stu dies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee want to be more clearly identified?. ### Response: publication bias would be an issue in the evidence and that a more comprehensive search strategy not limited to larger stu dies.


Instruction: What was the most obvious deficiency for the committee?

Output: quality of life data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the most obvious deficiency for the committee?. ### Response: quality of life data.


Instruction: The committee had reservations about what?

Output: the trial designs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee had reservations about what?. ### Response: the trial designs.


Instruction: The evidence as presented compared active interventions with what type of care?

Output: usual care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The evidence as presented compared active interventions with what type of care?. ### Response: usual care.


Instruction: What could result in a ‘placebo’?

Output: direct advice on changing management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could result in a ‘placebo’?. ### Response: direct advice on changing management.


Instruction: What could result in a ‘placebo’ effect that would be subsumed within the likely effects of intervention?

Output: direct advice on changing management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could result in a ‘placebo’ effect that would be subsumed within the likely effects of intervention?. ### Response: direct advice on changing management.


Instruction: What would be dependent on the extent and adequacy of baseli ne management?

Output: trial results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be dependent on the extent and adequacy of baseli ne management?. ### Response: trial results.


Instruction: An ideally managed population recruited to a trial might be recruited to what?

Output: not show any benefit from additional intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: An ideally managed population recruited to a trial might be recruited to what?. ### Response: not show any benefit from additional intervention.


Instruction: What type of population might not show any benefit from additional intervention?

Output: ideally managed population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of population might not show any benefit from additional intervention?. ### Response: ideally managed population.


Instruction: What are the unit costs of BNP and NT -proBNP provided to aid committee discussion?

Output: 100pg/ml for BNP and 400pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the unit costs of BNP and NT -proBNP provided to aid committee discussion?. ### Response: 100pg/ml for BNP and 400pg/ml.


Instruction: How many sites provided unit cost information for BNP?

Output: Three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sites provided unit cost information for BNP?. ### Response: Three.


Instruction: How many sites provided unit cost information for NTproBNP?

Output: five

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sites provided unit cost information for NTproBNP?. ### Response: five.


Instruction: What is the average of these sites?

Output: five sites provided unit cost information for NTproBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average of these sites?. ### Response: five sites provided unit cost information for NTproBNP.


Instruction: How much did the cost of natriuretic peptide tests cost?

Output: £21.69

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did the cost of natriuretic peptide tests cost?. ### Response: £21.69.


Instruction: How much did NT-proBNP cost?

Output: £26.07

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did NT-proBNP cost?. ### Response: £26.07.


Instruction: What was identified as a priority for the original economic analysis?

Output: cost -effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was identified as a priority for the original economic analysis?. ### Response: cost -effectiveness.


Instruction: The committee sought to determine whether natriuretic peptide testing is cost -effective and what?

Output: what the most cost -effective diagnostic threshold should to refer for echocar diography and specialist clinical assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee sought to determine whether natriuretic peptide testing is cost -effective and what?. ### Response: what the most cost -effective diagnostic threshold should to refer for echocar diography and specialist clinical assessment.


Instruction: What is the most cost-effective diagnostic threshold to refer for echocar diography and specialist clinical assessment?

Output: natriuretic peptide testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most cost-effective diagnostic threshold to refer for echocar diography and specialist clinical assessment?. ### Response: natriuretic peptide testing.


Instruction: What has ESC lowered the ir recommended natriuretic peptide thresholds from?

Output: 100pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has ESC lowered the ir recommended natriuretic peptide thresholds from?. ### Response: 100pg/ml.


Instruction: What were the thresholds for BNP and NT -proBNP?

Output: 100pg/ml for BNP and 400pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the thresholds for BNP and NT -proBNP?. ### Response: 100pg/ml for BNP and 400pg/ml.


Instruction: What were previously recommended thresholds?

Output: 100pg/ml for BNP and 400pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were previously recommended thresholds?. ### Response: 100pg/ml for BNP and 400pg/ml.


Instruction: Why did the committee raise concerns that the threshold recommended in the 2010 Chronic Heart Failure guideline was too high?

Output: resulting in some patients with heart failure receiving a delayed diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did the committee raise concerns that the threshold recommended in the 2010 Chronic Heart Failure guideline was too high?. ### Response: resulting in some patients with heart failure receiving a delayed diagnosis.


Instruction: What was the 2010 CHF guideline in line with?

Output: the previous ESC thresholds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2010 CHF guideline in line with?. ### Response: the previous ESC thresholds.


Instruction: What may be too high for some patients with heart failure?

Output: the threshold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be too high for some patients with heart failure?. ### Response: the threshold.


Instruction: What could lower the threshold for earlier diagnosis and a better prognosis of these patients?

Output: ear lier diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could lower the threshold for earlier diagnosis and a better prognosis of these patients?. ### Response: ear lier diagnosis.


Instruction: What could greatly increase cost to the hospital?

Output: lowering the threshold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could greatly increase cost to the hospital?. ### Response: lowering the threshold.


Instruction: What may greatly increase the cost to the NHS?

Output: lowering the threshold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may greatly increase the cost to the NHS?. ### Response: lowering the threshold.


Instruction: What is unlikely to lead to a diagnosis of heart failure?

Output: referrals for echocardiography and specialist clinical assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unlikely to lead to a diagnosis of heart failure?. ### Response: referrals for echocardiography and specialist clinical assessment.


Instruction: What was undertaken for this question?

Output: o riginal cost -effectiveness modelling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was undertaken for this question?. ### Response: o riginal cost -effectiveness modelling.


Instruction: What is included in a summary of the results of the analysis?

Output: Evidence statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in a summary of the results of the analysis?. ### Response: Evidence statements.


Instruction: What was used to determine the most cost effective threshold level of natriuretic peptide fo r referral from primary care for echocardiography and specialist clinical?

Output: cost -utility analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to determine the most cost effective threshold level of natriuretic peptide fo r referral from primary care for echocardiography and specialist clinical?. ### Response: cost -utility analysis.


Instruction: What was used to estimate lifetime quality -adjusted life years and costs from a current UK NHS and personal social services perspective?

Output: A decision tree with an attached Markov model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to estimate lifetime quality -adjusted life years and costs from a current UK NHS and personal social services perspective?. ### Response: A decision tree with an attached Markov model.


Instruction: What did the decision tree with an attached Markov model estimate?

Output: lifetime quality -adjusted life years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the decision tree with an attached Markov model estimate?. ### Response: lifetime quality -adjusted life years.


Instruction: What was the discounting rate for costs and QALYs?

Output: 3.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the discounting rate for costs and QALYs?. ### Response: 3.5%.


Instruction: What is the population entering the model?

Output: those presenting to primary care with signs and symptom s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population entering the model?. ### Response: those presenting to primary care with signs and symptom s.


Instruction: What is cytochrome P450 2C19681G3A polymorphism associated with?

Output: adverse 1-year clinical outcome of elective percutaneouscoronary intervention with drug-eluting or bare-metal stents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cytochrome P450 2C19681G3A polymorphism associated with?. ### Response: adverse 1-year clinical outcome of elective percutaneouscoronary intervention with drug-eluting or bare-metal stents.


Instruction: What is the adverse 1-year clinical outcome of elective percutaneouscoronary intervention with drug-eluting or bare-metal stents?

Output: Cytochrome P450 2C19681G3A polymorphism and high on-clopidogrel platelet reactivity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the adverse 1-year clinical outcome of elective percutaneouscoronary intervention with drug-eluting or bare-metal stents?. ### Response: Cytochrome P450 2C19681G3A polymorphism and high on-clopidogrel platelet reactivity.


Instruction: When did J Am CollCardiol. 2008:51:1925-34.28?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am CollCardiol. 2008:51:1925-34.28?. ### Response: 2007.


Instruction: What is the relationship between Cytochrome P450 genetic polymorphisms and the response to prasugrel?

Output: relationship to pharmaco-kinetic, pharmacodynamic, and clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between Cytochrome P450 genetic polymorphisms and the response to prasugrel?. ### Response: relationship to pharmaco-kinetic, pharmacodynamic, and clinical outcomes.


Instruction: When was Circulation. 2009;119:2553-60.29?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation. 2009;119:2553-60.29?. ### Response: 2009.


Instruction: What does genetic variation of CYP2C19 affect in patients with coronary arterydisease?

Output: both pharmacokinetic and pharmacodynamic responses to clopi-dogrel but not prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does genetic variation of CYP2C19 affect in patients with coronary arterydisease?. ### Response: both pharmacokinetic and pharmacodynamic responses to clopi-dogrel but not prasugrel.


Instruction: What is the first reversible oral adenosinediphosphate receptor antagonist compared with clopidogrel in patients with non-ST-segment elevation acute coronary syndrome?

Output: AZD6140

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first reversible oral adenosinediphosphate receptor antagonist compared with clopidogrel in patients with non-ST-segment elevation acute coronary syndrome?. ### Response: AZD6140.


Instruction: What was the primary result of the DISPERSE-2 trial?

Output: D6140, the first reversible oral adenosinediphosphate receptor antagonist, compared with clopidogrel, in patientswith non-ST-segment elevation acute coronary syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary result of the DISPERSE-2 trial?. ### Response: D6140, the first reversible oral adenosinediphosphate receptor antagonist, compared with clopidogrel, in patientswith non-ST-segment elevation acute coronary syndrome.


Instruction: What was the primary outcome of the DISPERSE-2 trial?

Output: D6140, the first reversible oral adenosinediphosphate receptor antagonist, compared with clopidogrel, in patientswith non-ST-segment elevation acute coronary syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome of the DISPERSE-2 trial?. ### Response: D6140, the first reversible oral adenosinediphosphate receptor antagonist, compared with clopidogrel, in patientswith non-ST-segment elevation acute coronary syndrome.


Instruction: What is CYP2C19 genotype, clopidogrelmetabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis?

Output: Holmes MV, Perel P, Shah T, et al. CYP2C19 genotype, clopidogrelmetabolism, platelet function, and cardiovascular events: a systematicreview

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CYP2C19 genotype, clopidogrelmetabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis?. ### Response: Holmes MV, Perel P, Shah T, et al. CYP2C19 genotype, clopidogrelmetabolism, platelet function, and cardiovascular events: a systematicreview.


Instruction: What is the name of the randomised factorialtrial?

Output: Double-dose versusstandard-dose clopidogrel and high-dose versus low-dose aspirin inindividuals undergoing percutaneous coronary intervention for acutecoronary syndromes (CURRENT-OASIS 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised factorialtrial?. ### Response: Double-dose versusstandard-dose clopidogrel and high-dose versus low-dose aspirin inindividuals undergoing percutaneous coronary intervention for acutecoronary syndromes (CURRENT-OASIS 7.


Instruction: What is clopidogrel and aspirin used for in acute coronary syndromes?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel and aspirin used for in acute coronary syndromes?. ### Response: percutaneous coronary intervention.


Instruction: What is aspirin used for in acute coronary syndromes?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aspirin used for in acute coronary syndromes?. ### Response: percutaneous coronary intervention.


Instruction: What is the ACCF/ACG/AHA consensus document on reducing the gastrointestinal risks of?

Output: antiplatelet therapy and NSAID use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACCF/ACG/AHA consensus document on reducing the gastrointestinal risks of?. ### Response: antiplatelet therapy and NSAID use.


Instruction: What is the force on Clinical Expert Consensus Doc-uments?

Output: American College ofCardiology Foundation Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the force on Clinical Expert Consensus Doc-uments?. ### Response: American College ofCardiology Foundation Task Force.


Instruction: What is a population-based study of the drug interaction between proton pump inhibitors and clopidogrel?

Output: DISPERSE-2 trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a population-based study of the drug interaction between proton pump inhibitors and clopidogrel?. ### Response: DISPERSE-2 trial.


Instruction: What is the name of the double-blind study that investigated the effect of omeprazole on platelet action of clopidogrel and aspirin?

Output: OCLA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the double-blind study that investigated the effect of omeprazole on platelet action of clopidogrel and aspirin?. ### Response: OCLA.


Instruction: What is a proton-pump inhibitor?

Output: antiplatelet effects of clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a proton-pump inhibitor?. ### Response: antiplatelet effects of clopidogrel.


Instruction: What is the name of the double-blind, ran-domized study?

Output: OCLA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the double-blind, ran-domized study?. ### Response: OCLA.


Instruction: What is OCLA?

Output: Omeprazole CLopidogrel Aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is OCLA?. ### Response: Omeprazole CLopidogrel Aspirin.


Instruction: When was the study published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the study published?. ### Response: 2010.


Instruction: What type of literature examinedpatient experiences and priorities?

Output: tative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of literature examinedpatient experiences and priorities?. ### Response: tative.


Instruction: What was considered in the formulation of recommendations, but not un-dertaken?

Output: resource implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered in the formulation of recommendations, but not un-dertaken?. ### Response: resource implications.


Instruction: What is the name of the section that highlights some impor tant changes t hat ma y result fr om implementing t his guideline identified at publication in July 2014?

Output: g etting star ted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the section that highlights some impor tant changes t hat ma y result fr om implementing t his guideline identified at publication in July 2014?. ### Response: g etting star ted.


Instruction: How many inputs did stakeholders, e xper ts and healt h professionals receive?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many inputs did stakeholders, e xper ts and healt h professionals receive?. ### Response: 3.


Instruction: How many areas have been identified that could have a big impact on practice or could be challenging to implement?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many areas have been identified that could have a big impact on practice or could be challenging to implement?. ### Response: 3.


Instruction: What would be needed to fully implement t he guideline?

Output: other changes t o practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be needed to fully implement t he guideline?. ### Response: other changes t o practice.


Instruction: What is a non-HDL cholester ol?

Output: Non-high-density lipopr otein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a non-HDL cholester ol?. ### Response: Non-high-density lipopr otein.


Instruction: What is another term for non-high-density lipopr otein?

Output: LDL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for non-high-density lipopr otein?. ### Response: LDL.


Instruction: Is it necessary to fully implement the guideline?

Output: Ho wever, other changes t o practice ma y be needed t o fully implement t he guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is it necessary to fully implement the guideline?. ### Response: Ho wever, other changes t o practice ma y be needed t o fully implement t he guideline.


Instruction: Non-HDL cholest erol is seen to be a bett er car diovascular disease (CVD) risk indicator than what?

Output: lo w-density lipopr otein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Non-HDL cholest erol is seen to be a bett er car diovascular disease (CVD) risk indicator than what?. ### Response: lo w-density lipopr otein.


Instruction: What is the mor e accurat e, practical and cost eff ective of Non-high-density lipopr otein?

Output: cholest erol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mor e accurat e, practical and cost eff ective of Non-high-density lipopr otein?. ### Response: cholest erol.


Instruction: What is not needed for a f asting blood sample?

Output: A f asting blood sample is not needed. This is more con venient f or patient s and ma y reduce t he need f or additional blood samples

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not needed for a f asting blood sample?. ### Response: A f asting blood sample is not needed. This is more con venient f or patient s and ma y reduce t he need f or additional blood samples.


Instruction: What is more convenient f or patient s and reduce t he need for additional blood samples?

Output: A f asting blood sample

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more convenient f or patient s and reduce t he need for additional blood samples?. ### Response: A f asting blood sample.


Instruction: Who is equesting lipids?

Output: GPs, practice nurses and community pharmacist s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is equesting lipids?. ### Response: GPs, practice nurses and community pharmacist s.


Instruction: What do GPs, practice nurses and community pharmacists need to do?

Output: change t heir practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do GPs, practice nurses and community pharmacists need to do?. ### Response: change t heir practice.


Instruction: What do Laborat ories also need to change?

Output: t heir r epor ting pr ocedur es

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do Laborat ories also need to change?. ### Response: t heir r epor ting pr ocedur es.


Instruction: What percentage of laborat ories included non-HDL cholest erol in their repor ts?

Output: 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of laborat ories included non-HDL cholest erol in their repor ts?. ### Response: 10%.


Instruction: What is the UKNEQ AS?

Output: The Unit ed K ingdom National Ext ernal Quality Assessment Ser vice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the UKNEQ AS?. ### Response: The Unit ed K ingdom National Ext ernal Quality Assessment Ser vice.


Instruction: Why was there a lack of demand for healt hcare workers?

Output: Healt hcare workers ma y need educating

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there a lack of demand for healt hcare workers?. ### Response: Healt hcare workers ma y need educating.


Instruction: What does the non-HDL cholest erol test mean?

Output: It is mor e accurat e, mor e practical and cost eff ect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the non-HDL cholest erol test mean?. ### Response: It is mor e accurat e, mor e practical and cost eff ect.


Instruction: How do workers interpret the laborat ory results?

Output: ma y need t o change t heir practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do workers interpret the laborat ory results?. ### Response: ma y need t o change t heir practice.


Instruction: What is a risk assessment and r eduction, including lipid modification?

Output: Cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk assessment and r eduction, including lipid modification?. ### Response: Cardiovascular disease.


Instruction: What is the last updat ed 10 F ebruar?

Output: 2023Page 26of 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 10 F ebruar?. ### Response: 2023Page 26of 40.


Instruction: What is the last updat ed 10 F ebruar y 2023Page 26of 40?

Output: Notice of right s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 10 F ebruar y 2023Page 26of 40?. ### Response: Notice of right s.


Instruction: What is typhoid myocarditis?

Output: 85:336–7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is typhoid myocarditis?. ### Response: 85:336–7.


Instruction: What is the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure?

Output: ESC guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure?. ### Response: ESC guidelines.


Instruction: What is Chronic Heart Failure 2012 of the European Society of Cardiology?

Output: the Task Force for the Diagnosis and Treatment of Acute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chronic Heart Failure 2012 of the European Society of Cardiology?. ### Response: the Task Force for the Diagnosis and Treatment of Acute.


Instruction: What is the acronym for Heart Failure Association of the ESC?

Output: HFA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Heart Failure Association of the ESC?. ### Response: HFA.


Instruction: When did Eur J Heart Fail.14:803-69.

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Heart Fail.14:803-69.. ### Response: 2012.


Instruction: When was Giant cell myocarditis diagnosed?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Giant cell myocarditis diagnosed?. ### Response: 2012.


Instruction: What is a review to push action?

Output: Cardiac involvement in acquired immunodeficiency syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a review to push action?. ### Response: Cardiac involvement in acquired immunodeficiency syndrome.


Instruction: What is the Committee for the Study of Cardiac Involvement in AIDS?

Output: a review to push action

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Committee for the Study of Cardiac Involvement in AIDS?. ### Response: a review to push action.


Instruction: What is a review of the disease spectrum and clinical management of HIV/AIDS?

Output: Cardiac manifestations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a review of the disease spectrum and clinical management of HIV/AIDS?. ### Response: Cardiac manifestations.


Instruction: When was J Acquir Immune Defic Syndr Hum Retrovirol. 18:145–54?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was J Acquir Immune Defic Syndr Hum Retrovirol. 18:145–54?. ### Response: 1998.


Instruction: What is the initial presentation of pediatric systemic lupus erythe-matosus?

Output: Acute myocarditis and ventricular fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the initial presentation of pediatric systemic lupus erythe-matosus?. ### Response: Acute myocarditis and ventricular fibrillation.


Instruction: What is Chagas' heart disease?

Output: Acute myocarditis and ventricular fibrillation as initial presentation of pediatric systemic lupus erythe-matosus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chagas' heart disease?. ### Response: Acute myocarditis and ventricular fibrillation as initial presentation of pediatric systemic lupus erythe-matosus.


Instruction: What are implantable cardioverter defibrillators different from in Chagas patients?

Output: patients with coronary disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implantable cardioverter defibrillators different from in Chagas patients?. ### Response: patients with coronary disease.


Instruction: When did Pacing Clin Electrophysiol. 1997;20:194-7.

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Pacing Clin Electrophysiol. 1997;20:194-7.. ### Response: 1997.


Instruction: What is Chagas' VT complicating?

Output: Efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chagas' VT complicating?. ### Response: Efficacy and safety.


Instruction: What is a new perspective on cath-eter-based ablation of?

Output: ventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new perspective on cath-eter-based ablation of?. ### Response: ventricular tachycardia.


Instruction: What does WIF stand for?

Output: Wearable defibrillator use in heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does WIF stand for?. ### Response: Wearable defibrillator use in heart failure.


Instruction: What is the name of the prospective registry of wearable defibrillator use in heart failure?

Output: Pacing Clin Electrophysiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective registry of wearable defibrillator use in heart failure?. ### Response: Pacing Clin Electrophysiol.


Instruction: What type of defibrillator is used to terminate tachyarrhythmias in patients at high risk for sudden death?

Output: wearable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of defibrillator is used to terminate tachyarrhythmias in patients at high risk for sudden death?. ### Response: wearable.


Instruction: What are the results of the WEARIT/BIROAD?

Output: Use of a wearable defibrillator in terminating tachyarrhythmias in patients at high risk for sudden death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the WEARIT/BIROAD?. ### Response: Use of a wearable defibrillator in terminating tachyarrhythmias in patients at high risk for sudden death.


Instruction: Cooper LT, Okura Y. Idiopathic what?

Output: giant cell myocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cooper LT, Okura Y. Idiopathic what?. ### Response: giant cell myocarditis.


Instruction: What is the name of the Japanese patient with cardiac sarcoidosis treated with prednisone?

Output: Yazaki Y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Japanese patient with cardiac sarcoidosis treated with prednisone?. ### Response: Yazaki Y.


Instruction: What is the name of the drug used to treat Japanese patients with cardiac sarcoidosis?

Output: prednisone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat Japanese patients with cardiac sarcoidosis?. ### Response: prednisone.


Instruction: When was the Am J Cardiol. 88:1006-10?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol. 88:1006-10?. ### Response: 2001.


Instruction: What is one of the benefits of implant-able cardiac defibrillators?

Output: safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the benefits of implant-able cardiac defibrillators?. ### Response: safety.


Instruction: What type of disease is sarcoidosis?

Output: Cardiac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of disease is sarcoidosis?. ### Response: Cardiac.


Instruction: What is the name of the journal that published a study on sarcoidosis in 2013?

Output: ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published a study on sarcoidosis in 2013?. ### Response: ahajournals.org.


Instruction: When was this study published?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 23, 2023.


Instruction: What is a pproach to care?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pproach to care?. ### Response: Chronic Heart Failure.


Instruction: In what year was the PREFER trial by Brannstrom et al. included?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the PREFER trial by Brannstrom et al. included?. ### Response: 2014.


Instruction: What year was an MDT included in the clinical review?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was an MDT included in the clinical review?. ### Response: 2008.


Instruction: What did this study suggest is likely to be cost saving compared to usual care?

Output: an MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did this study suggest is likely to be cost saving compared to usual care?. ### Response: an MDT.