Instruction: Where is the Institute ofMedicine located?

Output: US

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Institute ofMedicine located?. ### Response: US.


Instruction: Where are the Standards for Systematic Reviews published?

Output: Washington, DC:National Academies Press

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the Standards for Systematic Reviews published?. ### Response: Washington, DC:National Academies Press.


Instruction: Who published the ACC/AHA statement?

Output: American College of Cardiology/Amer-ican Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the ACC/AHA statement?. ### Response: American College of Cardiology/Amer-ican Heart Association.


Instruction: What is the name of the Task Force on PerformanceMeasures and Practice Guidelines?

Output: American College of Cardiology/Amer-ican Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on PerformanceMeasures and Practice Guidelines?. ### Response: American College of Cardiology/Amer-ican Heart Association.


Instruction: What are the names of the AHA/ACC/HHS strategies?

Output: Arnett DK, Goodman RA, Halperin JL, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the AHA/ACC/HHS strategies?. ### Response: Arnett DK, Goodman RA, Halperin JL, et al.


Instruction: What was the temporal relationship between INRtest interval and the outcome of the study?

Output: unclear

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the temporal relationship between INRtest interval and the outcome of the study?. ### Response: unclear.


Instruction: The outcome itself would have an impact on thedetermination of what?

Output: the test interval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The outcome itself would have an impact on thedetermination of what?. ### Response: the test interval.


Instruction: What was different about the study population?

Output: differentfrom patients receiving INR monitoring and VKA dose adjustmentsfrom their anticoagulation providers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was different about the study population?. ### Response: differentfrom patients receiving INR monitoring and VKA dose adjustmentsfrom their anticoagulation providers.


Instruction: What was the association between center next-visit INR interval ratio and site-level TTR?

Output: increased with shorter INR recall intervals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the association between center next-visit INR interval ratio and site-level TTR?. ### Response: increased with shorter INR recall intervals.


Instruction: What is the mean number of days after a visit with an INR outside the therapeuticrange divided by?

Output: next-visit INR interval ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mean number of days after a visit with an INR outside the therapeuticrange divided by?. ### Response: next-visit INR interval ratio.


Instruction: What increased with shorter INR recall intervals?

Output: site-level TTR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increased with shorter INR recall intervals?. ### Response: site-level TTR.


Instruction: What did the panel assume increased with more frequent INR testing?

Output: greater burden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the panel assume increased with more frequent INR testing?. ### Response: greater burden.


Instruction: What did the guideline panel determine about the net health benefit/harm associated with an out-of-range INR?

Output: there is very low certaintyevidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the guideline panel determine about the net health benefit/harm associated with an out-of-range INR?. ### Response: there is very low certaintyevidence.


Instruction: What was little evidence bearing on other criteria?

Output: had littleimpact on the recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was little evidence bearing on other criteria?. ### Response: had littleimpact on the recommendation.


Instruction: What is the benefit/harm associated with the INR recallinterval following an out-of-range INR?

Output: greater burden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit/harm associated with the INR recallinterval following an out-of-range INR?. ### Response: greater burden.


Instruction: What was the panel able to suggest vs longer intervals?

Output: INR recallintervals of 4 weeks or less

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the panel able to suggest vs longer intervals?. ### Response: INR recallintervals of 4 weeks or less.


Instruction: Most patients areadverse to frequent INR monitoring yet will return for what?

Output: INRs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most patients areadverse to frequent INR monitoring yet will return for what?. ### Response: INRs.


Instruction: What should guide the choice for the INR recall interval?

Output: How much the INR is outof range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should guide the choice for the INR recall interval?. ### Response: How much the INR is outof range.


Instruction: What should be the etiology of the out-of-range INR?

Output: How much the INR is outof range should guide the choice for the INR recall interval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the etiology of the out-of-range INR?. ### Response: How much the INR is outof range should guide the choice for the INR recall interval.


Instruction: A recall interval between 2 and 4 weeks might be what?

Output: reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A recall interval between 2 and 4 weeks might be what?. ### Response: reasonable.


Instruction: How long might be reasonable following a doseadjustment for an INR of 3.3 in a patient with generally stable INRcontrol?

Output: between 2 and 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long might be reasonable following a doseadjustment for an INR of 3.3 in a patient with generally stable INRcontrol?. ### Response: between 2 and 4 weeks.


Instruction: What might be needed after a temporary interruption of VKA following an iNR of 8.2?

Output: a recall interval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be needed after a temporary interruption of VKA following an iNR of 8.2?. ### Response: a recall interval.


Instruction: A patient who recently started taking VKA might need a recall interval not exceeding what?

Output: a few days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A patient who recently started taking VKA might need a recall interval not exceeding what?. ### Response: a few days.


Instruction: What is an INR of 8.2in a patient who recently started taking antibiotics?

Output: a recall interval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an INR of 8.2in a patient who recently started taking antibiotics?. ### Response: a recall interval.


Instruction: What is a strategy of using 1-week recall intervals for INRs that are farther out of range?

Output: reduce the risk of mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strategy of using 1-week recall intervals for INRs that are farther out of range?. ### Response: reduce the risk of mortality.


Instruction: What can recall intervals reduce the risk of mortality, recurrent VTE, and bleeding?

Output: 1-week recall intervals for INRs that are fartherout of range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can recall intervals reduce the risk of mortality, recurrent VTE, and bleeding?. ### Response: 1-week recall intervals for INRs that are fartherout of range.


Instruction: What couldpharmacogenomic testing help inform INR recalls by helping to predict the time required for a given patient to reach a new steady state?

Output: VKA dose adjustments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What couldpharmacogenomic testing help inform INR recalls by helping to predict the time required for a given patient to reach a new steady state?. ### Response: VKA dose adjustments.


Instruction: How long should a longer INR recall interval be used for patients receiving maintenance VKA therapy for treatment of VTE?

Output: 6-12 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should a longer INR recall interval be used for patients receiving maintenance VKA therapy for treatment of VTE?. ### Response: 6-12 weeks.


Instruction: How long is the INR recall interval for patients receiving maintenance VKA therapy for treatmentof VTE?

Output: 6-12 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the INR recall interval for patients receiving maintenance VKA therapy for treatmentof VTE?. ### Response: 6-12 weeks.


Instruction: What does the ASH guideline panel suggest?

Output: using a longer (6-12weeks) INR recall interval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ASH guideline panel suggest?. ### Response: using a longer (6-12weeks) INR recall interval.


Instruction: What is less accurate than TTE and TEE for identifying valvular vegetation and perfo-rations?

Output: CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less accurate than TTE and TEE for identifying valvular vegetation and perfo-rations?. ### Response: CT.


Instruction: What is CT useful for evaluating patients with equivocal findings on TEE?

Output: CT is less accurate than TTE and TEE for identifying valvular vegetation and valvular perfo-rations, CT is useful for evaluating patients with equivocal findings on TEE and for evaluating com-plications in patients with suspected paravalvular infection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CT useful for evaluating patients with equivocal findings on TEE?. ### Response: CT is less accurate than TTE and TEE for identifying valvular vegetation and valvular perfo-rations, CT is useful for evaluating patients with equivocal findings on TEE and for evaluating com-plications in patients with suspected paravalvular infection.


Instruction: What is particularly useful in pre-operative evaluation of patients with aortic valve IE?

Output: CT imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is particularly useful in pre-operative evaluation of patients with aortic valve IE?. ### Response: CT imaging.


Instruction: What is less affected by the shadowing of mechanical valves or bioprosthetic valve sew-ing rings than is ultrasonography?

Output: cardiac CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less affected by the shadowing of mechanical valves or bioprosthetic valve sew-ing rings than is ultrasonography?. ### Response: cardiac CT.


Instruction: What allows evaluation of the motion of mechanical valve occluders?

Output: CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What allows evaluation of the motion of mechanical valve occluders?. ### Response: CT.


Instruction: What provides visualization of throm-bus?

Output: CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides visualization of throm-bus?. ### Response: CT.


Instruction: Cardiovascular valvular fluoroscopy can be an adjunct to other what?

Output: clinical and imaging information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cardiovascular valvular fluoroscopy can be an adjunct to other what?. ### Response: clinical and imaging information.


Instruction: What can be an adjunct to other clinical and imaging information to detect the presence of obstructive disease in mechanical prosthetic valves?

Output: 18F-fluorodeoxyglucose PET/CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be an adjunct to other clinical and imaging information to detect the presence of obstructive disease in mechanical prosthetic valves?. ### Response: 18F-fluorodeoxyglucose PET/CT.


Instruction: What can still be a vexing under -taking?

Output: Diagnosis of IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can still be a vexing under -taking?. ### Response: Diagnosis of IE.


Instruction: What increases the diagnostic capability of the Modified Duke Criteria?

Output: initial presentation of patients with suspected pros-thetic valve endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the diagnostic capability of the Modified Duke Criteria?. ### Response: initial presentation of patients with suspected pros-thetic valve endocarditis.


Instruction: What percentage of patients with prosthetic valve endocarditis were recatego-rized after the inclusion of abnormal 18F-fluorodeoxyglucose?

Output: 76%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with prosthetic valve endocarditis were recatego-rized after the inclusion of abnormal 18F-fluorodeoxyglucose?. ### Response: 76%.


Instruction: How many patients with prosthetic valve endocarditis were recatego-rized?

Output: 76%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with prosthetic valve endocarditis were recatego-rized?. ### Response: 76%.


Instruction: What percentage of patients were initially classified as “possible” IE on admission to the hospital?

Output: 76%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients were initially classified as “possible” IE on admission to the hospital?. ### Response: 76%.


Instruction: Where must this tool be used because it may be prone to false-positive results?

Output: centers with great experi-ence with the technology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where must this tool be used because it may be prone to false-positive results?. ### Response: centers with great experi-ence with the technology.


Instruction: What may be prone to false-positive results?

Output: implanted prosthetic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be prone to false-positive results?. ### Response: implanted prosthetic valves.


Instruction: What may also be considered a complementary diagnostic tool for some patients with suspected native valve endocarditis?

Output: 18F-fluorodeoxyglucose PET/CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may also be considered a complementary diagnostic tool for some patients with suspected native valve endocarditis?. ### Response: 18F-fluorodeoxyglucose PET/CT.


Instruction: Why is the frequency of IE among patients with S. aureus bacteremia reported to be?

Output: 30%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the frequency of IE among patients with S. aureus bacteremia reported to be?. ### Response: 30%,.


Instruction: What percentage of patients with S. aureus bacteremia have TEE?

Output: 30%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with S. aureus bacteremia have TEE?. ### Response: 30%,.


Instruction: What may be considered to rule out IE?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered to rule out IE?. ### Response: TEE.


Instruction: What is an example of a known extracardiac source?

Output: an infected joint or joint prosthe-sis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a known extracardiac source?. ### Response: an infected joint or joint prosthe-sis.


Instruction: What might be considered if there are known cases of seeding of valve tissue in this type of setting?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered if there are known cases of seeding of valve tissue in this type of setting?. ### Response: TEE.


Instruction: How long does it take for symptoms of IE to resolve?

Output: 72 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for symptoms of IE to resolve?. ### Response: 72 hours.


Instruction: What is the name of the website that ahajournals.org was able to access on April 27, 2023?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the website that ahajournals.org was able to access on April 27, 2023?. ### Response: http://ahajournals.org.


Instruction: How many hours after removal of a bacteremia and fever resolves?

Output: 72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours after removal of a bacteremia and fever resolves?. ### Response: 72.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertensi on in the Primary Care Setting March 2020 Page 112 of 134 Question Set # Concept Strategy Questions 5 and 6 – Blood pressure thresholds and goals for pharmacologic interventions?

Output: hypertension, prehypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertensi on in the Primary Care Setting March 2020 Page 112 of 134 Question Set # Concept Strategy Questions 5 and 6 – Blood pressure thresholds and goals for pharmacologic interventions?. ### Response: hypertension, prehypertension.


Instruction: What are pressure thresholds and goals for pharmacologic interventions #1 hypertension, prehypertension?

Output: Blood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are pressure thresholds and goals for pharmacologic interventions #1 hypertension, prehypertension?. ### Response: Blood.


Instruction: What is another name for white coat hypertension/exp OR ‘masked hypertension’?

Output: WCH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for white coat hypertension/exp OR ‘masked hypertension’?. ### Response: WCH.


Instruction: What is another name for white coat hypertension?

Output: masked hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for white coat hypertension?. ### Response: masked hypertension.


Instruction: What is the other name for high or elevated or borderline?

Output: lower OR lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the other name for high or elevated or borderline?. ### Response: lower OR lowering.


Instruction: What is the name of the OR #2 OR #3 #5 Blood pressure?

Output: diastolic blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the OR #2 OR #3 #5 Blood pressure?. ### Response: diastolic blood pressure.


Instruction: What is'systolic blood pressure' supposed to be?

Output: NEAR/3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is'systolic blood pressure' supposed to be?. ### Response: NEAR/3.


Instruction: What is sbp:ti,ab OR?

Output: dpb:ti,ab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is sbp:ti,ab OR?. ### Response: dpb:ti,ab.


Instruction: What is diastol?

Output: *:ti,ab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is diastol?. ### Response: *:ti,ab.


Instruction: How many mmhg is '70 mmg'?

Output: #7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mmhg is '70 mmg'?. ### Response: #7.


Instruction: How many mmhg':ti,ab OR '170 mmg'?

Output: 160

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mmhg':ti,ab OR '170 mmg'?. ### Response: 160.


Instruction: What is the blood pressure goal*?

Output: NEAR/3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the blood pressure goal*?. ### Response: NEAR/3.


Instruction: What does target*:ti,ab stand for?

Output: prehyperten

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does target*:ti,ab stand for?. ### Response: prehyperten.


Instruction: What is the name of the antihypertensive drug therapy that targets hypertension?

Output: antihypertens*:ti,ab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the antihypertensive drug therapy that targets hypertension?. ### Response: antihypertens*:ti,ab.


Instruction: What is the name of the antihypertens*:ti,ab OR 'anti hypertens**':tab?

Output: antihypertens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the antihypertens*:ti,ab OR 'anti hypertens**':tab?. ### Response: antihypertens.


Instruction: What are the names of the drugs that are used to treat hypertension?

Output: Antihypertensive drug therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the drugs that are used to treat hypertension?. ### Response: Antihypertensive drug therapy.


Instruction: How many questions do you have to answer in order to answer the questions?

Output: 7, 8, and 9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many questions do you have to answer in order to answer the questions?. ### Response: 7, 8, and 9.


Instruction: #15 Apply hedges below Questions 7, 8 and 9 – Pharmacologic interventions #1 What is #1 Hypertension, prehypertension?

Output: Hypertension, prehypertension. WCH  ‘hypertension’/exp OR ‘hypertensive patient’/exp OR ‘resistant hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: #15 Apply hedges below Questions 7, 8 and 9 – Pharmacologic interventions #1 What is #1 Hypertension, prehypertension?. ### Response: Hypertension, prehypertension. WCH  ‘hypertension’/exp OR ‘hypertensive patient’/exp OR ‘resistant hypertension.


Instruction: What is #2 Hypertension:ti,ab OR hypertensive?

Output: ‘borderline hypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is #2 Hypertension:ti,ab OR hypertensive?. ### Response: ‘borderline hypertensive.


Instruction: What is another name for hypertension?

Output: prehypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for hypertension?. ### Response: prehypertension.


Instruction: What is the other name for prehyperten?

Output: *:ti,ab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the other name for prehyperten?. ### Response: *:ti,ab.


Instruction: How is hypertension defined?

Output: prehypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is hypertension defined?. ### Response: prehypertension.


Instruction: What is the NEAR/3 ‘blood pressure’?

Output: (high OR elevated OR borderline OR low OR lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NEAR/3 ‘blood pressure’?. ### Response: (high OR elevated OR borderline OR low OR lowering.


Instruction: What does #3 mean?

Output: high OR elevated OR borderline OR lower OR lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does #3 mean?. ### Response: high OR elevated OR borderline OR lower OR lowering.


Instruction: What is the name of the 2017 VA/SCD GuidelineCirculation?

Output: Al-Khatib

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2017 VA/SCD GuidelineCirculation?. ### Response: Al-Khatib.


Instruction: What are the names of the authors?

Output: Massing MW, Simpson RJ Jr, Rautaharju PM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors?. ### Response: Massing MW, Simpson RJ Jr, Rautaharju PM.


Instruction: Who is a HRS/EHRA/APHRS expert?

Output: Wilde AA, Horie M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a HRS/EHRA/APHRS expert?. ### Response: Wilde AA, Horie M.


Instruction: When was the N Engl J Med 375?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 375?. ### Response: 2016.


Instruction: What is a con-sensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes?

Output: HRS/EHRA/APHRS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a con-sensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes?. ### Response: HRS/EHRA/APHRS.


Instruction: What is the name of the statement given by Priori SG, Wilde AA, Horie M, et al.?

Output: HRS/EHRA/APHRS expert con-sensus statement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the statement given by Priori SG, Wilde AA, Horie M, et al.?. ### Response: HRS/EHRA/APHRS expert con-sensus statement.


Instruction: How many individu-als did Hiss RG, Lamb LE study?

Output: 122 043

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many individu-als did Hiss RG, Lamb LE study?. ### Response: 122 043.


Instruction: S2.2.2-6. Brodsky M, Wu D, Denes P, et al. Arrhythmias documented by 24 hour continuous electrocardiographic monitoring in 50 male medical students without apparent heart disease.

Output: 1962;25:947–61

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: S2.2.2-6. Brodsky M, Wu D, Denes P, et al. Arrhythmias documented by 24 hour continuous electrocardiographic monitoring in 50 male medical students without apparent heart disease.. ### Response: 1962;25:947–61.


Instruction: Am J Cardiol. 1977;39:390-5.

Output: 24 hour continuous electrocardiographic monitoring in 50 male medical students without apparent heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Am J Cardiol. 1977;39:390-5.. ### Response: 24 hour continuous electrocardiographic monitoring in 50 male medical students without apparent heart disease.


Instruction: What is used to predict coronary heart disease events and mortality?

Output: ventricular premature complexes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to predict coronary heart disease events and mortality?. ### Response: ventricular premature complexes.


Instruction: What is the Atherosclerosis Risk In Communities cohort used for?

Output: Usefulness of ventricular premature complexes to predict coronary heart disease events and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Atherosclerosis Risk In Communities cohort used for?. ### Response: Usefulness of ventricular premature complexes to predict coronary heart disease events and mortality.


Instruction: Who is the author of Premature cardiac contractions and risk of incident ischemic stroke?

Output: Ofoma U, He F, Shaffer ML

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Premature cardiac contractions and risk of incident ischemic stroke?. ### Response: Ofoma U, He F, Shaffer ML.


Instruction: When did the J Am Heart Assoc. 2012 issue 1:e002519 appear?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Heart Assoc. 2012 issue 1:e002519 appear?. ### Response: 2012.


Instruction: What is the term for incident ischemic stroke?

Output: S2.2.2-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for incident ischemic stroke?. ### Response: S2.2.2-9.


Instruction: What is a term for ventricular premature complexes and their relation to cardiac mortality in gen-eral populations?

Output: Quinidine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for ventricular premature complexes and their relation to cardiac mortality in gen-eral populations?. ### Response: Quinidine.


Instruction: In what year was the Am J Cardiol.112:1263-70 published?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Am J Cardiol.112:1263-70 published?. ### Response: 2013.


Instruction: What is the long-term outcome of multiform premature ventricular complexes in structurally normal hearts?

Output: coronary heart disease events and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term outcome of multiform premature ventricular complexes in structurally normal hearts?. ### Response: coronary heart disease events and mortality.


Instruction: What are the results of the long term outcome of non-sustained ventricular tachycardia?

Output: structurally normal hearts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the long term outcome of non-sustained ventricular tachycardia?. ### Response: structurally normal hearts.


Instruction: What is the name of the study that investigated ventricular pre-mature complexes and sudden death after myocardial infarction?

Output: Atherosclerosis Risk In Communities cohort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated ventricular pre-mature complexes and sudden death after myocardial infarction?. ### Response: Atherosclerosis Risk In Communities cohort.


Instruction: What year did Circulation. 1981 have 64:297–305?

Output: 1981

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circulation. 1981 have 64:297–305?. ### Response: 1981.


Instruction: Which study examined the relationship between Ventricular premature beats and mortality?

Output: Atherosclerosis Risk In Communities cohort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which study examined the relationship between Ventricular premature beats and mortality?. ### Response: Atherosclerosis Risk In Communities cohort.


Instruction: How did Ruberman W, Weinblatt E, Goldberg JD, et al. compare mortality after an infarct?

Output: Ventricular prema-ture beats

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Ruberman W, Weinblatt E, Goldberg JD, et al. compare mortality after an infarct?. ### Response: Ventricular prema-ture beats.


Instruction: What antiarrhythmic agent did The Cardiac Arrhythmia Suppression Trial II Investigators study on?

Output: moricizine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What antiarrhythmic agent did The Cardiac Arrhythmia Suppression Trial II Investigators study on?. ### Response: moricizine.


Instruction: What is the effect of the antiatheric agent moricizine on survival after myocardial infarction?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of the antiatheric agent moricizine on survival after myocardial infarction?. ### Response: mortality.


Instruction: When was the N Engl J Med.327:227–33?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med.327:227–33?. ### Response: 1992.


Instruction: What is the name of the study that evaluated the mortality and morbidity of patients receiving encainide, flecainid, or placebo?

Output: The Cardiac Arrhythmia Suppression Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the mortality and morbidity of patients receiving encainide, flecainid, or placebo?. ### Response: The Cardiac Arrhythmia Suppression Trial.


Instruction: What is another name for the trial that examined the mortality of patients with ventricular arrhythmias?

Output: Cardiac Arrhythmia Suppression Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the trial that examined the mortality of patients with ventricular arrhythmias?. ### Response: Cardiac Arrhythmia Suppression Trial.


Instruction: When was the N Engl J Med's 324:781-8 published?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med's 324:781-8 published?. ### Response: 1991.


Instruction: How long did it take for patients to die from a heart attack?

Output: 1932–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for patients to die from a heart attack?. ### Response: 1932–.


Instruction: What is the name of the study that investigated the effect of d-sotalol on mortality in patients with left ventricular dysfunction?

Output: The SWORD Investigators. Survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effect of d-sotalol on mortality in patients with left ventricular dysfunction?. ### Response: The SWORD Investigators. Survival.


Instruction: What is the difference between the PST group and the control group?

Output: 22.4 points

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between the PST group and the control group?. ### Response: 22.4 points.


Instruction: What wasnoted in the self-testing group compared with the control?

Output: a cumulative gain inhealth utilities according to the Health Utilities Index Mark 319

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What wasnoted in the self-testing group compared with the control?. ### Response: a cumulative gain inhealth utilities according to the Health Utilities Index Mark 319.


Instruction: How much higher was TTR in the PSTgroup in studies assessing INR control?

Output: modestly higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was TTR in the PSTgroup in studies assessing INR control?. ### Response: modestly higher.


Instruction: What was lower for patients when PST was used than when other INRmonitoring methods were used?

Output: The risk of major bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was lower for patients when PST was used than when other INRmonitoring methods were used?. ### Response: The risk of major bleeding.


Instruction: What was used than when other INRmonitoring methods were used?

Output: PST

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used than when other INRmonitoring methods were used?. ### Response: PST.


Instruction: The guidelinepanel considered what criteria and considerations?

Output: EtD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The guidelinepanel considered what criteria and considerations?. ### Response: EtD.


Instruction: What is the average bleeding risk?

Output: 5fewer per 1000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average bleeding risk?. ### Response: 5fewer per 1000.


Instruction: What did the guidelinepanel consider to be associated with PSTresource requirements?

Output: moderate costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the guidelinepanel consider to be associated with PSTresource requirements?. ### Response: moderate costs.


Instruction: How many reviews did the likelihood of PST being cost-effective vary?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many reviews did the likelihood of PST being cost-effective vary?. ### Response: 1.


Instruction: How many reviews, RCTs, and modeling studies indicated that PST is likely to be cost-effective compared with usual care43-45?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many reviews, RCTs, and modeling studies indicated that PST is likely to be cost-effective compared with usual care43-45?. ### Response: 1.


Instruction: How many other reviews, including one RCT, and 1 modeling study, concluded thatPST is unlikely to becost-effective within accepted standards46,47?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many other reviews, including one RCT, and 1 modeling study, concluded thatPST is unlikely to becost-effective within accepted standards46,47?. ### Response: 2.


Instruction: What would PST implementation likely result in?

Output: reduced health equity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would PST implementation likely result in?. ### Response: reduced health equity.


Instruction: What is likely to result in reduced health equity for patients in lower socioeconomic classes and those with cognitiveproblems and poor manual dexterity?

Output: PST implementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to result in reduced health equity for patients in lower socioeconomic classes and those with cognitiveproblems and poor manual dexterity?. ### Response: PST implementation.


Instruction: Because some patients are notwilling to perform PST, the panel determined that the acceptability of PST to major stakeholders varies?

Output: deviationfrom this suggestion is appropriate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Because some patients are notwilling to perform PST, the panel determined that the acceptability of PST to major stakeholders varies?. ### Response: deviationfrom this suggestion is appropriate.


Instruction: What is needed to implement INR monitoring at home by the patient?

Output: substantial investment in patienttraining and testing equipment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to implement INR monitoring at home by the patient?. ### Response: substantial investment in patienttraining and testing equipment.


Instruction: What type of equipment is needed for INR testing?

Output: patienttraining and testing equipment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of equipment is needed for INR testing?. ### Response: patienttraining and testing equipment.


Instruction: What is the only other INR testing approach?

Output: PSM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only other INR testing approach?. ### Response: PSM.


Instruction: What is a condition of the VKA mainte-nance therapy?

Output: VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a condition of the VKA mainte-nance therapy?. ### Response: VTE.


Instruction: In settings where resources are limited, deviation from this suggestion is what?

Output: appropriate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In settings where resources are limited, deviation from this suggestion is what?. ### Response: appropriate.


Instruction: What should systems using PST be able to do?

Output: perform regular external quality assessment ofthe testing equipment and patient ’s ability to obtain accurate INRresults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should systems using PST be able to do?. ### Response: perform regular external quality assessment ofthe testing equipment and patient ’s ability to obtain accurate INRresults.


Instruction: The panel calls upon who?

Output: payers, including the Centers forMedicare and Medicaid Services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The panel calls upon who?. ### Response: payers, including the Centers forMedicare and Medicaid Services.


Instruction: What are payers required to do to ensure that unnecessary testing is not incentivized?

Output: make changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are payers required to do to ensure that unnecessary testing is not incentivized?. ### Response: make changes.


Instruction: What are providers and patients required to be aware of?

Output: this testing option

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are providers and patients required to be aware of?. ### Response: this testing option.


Instruction: What is available for those who would like to use PST?

Output: funding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is available for those who would like to use PST?. ### Response: funding.


Instruction: What is an example of a conservative strategy?

Output: Low-risk score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a conservative strategy?. ### Response: Low-risk score.


Instruction: What is another term for elevated cardiac biomarkers?

Output: TnT or TnI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for elevated cardiac biomarkers?. ### Response: TnT or TnI.


Instruction: What indicates coronary artery bypass graft?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates coronary artery bypass graft?. ### Response: CABG.


Instruction: What indicates patient or physician preference in the absence of high risk features?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates patient or physician preference in the absence of high risk features?. ### Response: CABG.


Instruction: What does GRACE stand for?

Output: Global Registry ofAcute Coronary Events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GRACE stand for?. ### Response: Global Registry ofAcute Coronary Events.


Instruction: When was al.4910 circulated?

Output: August 14, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was al.4910 circulated?. ### Response: August 14, 2012.


Instruction: When was the download from http://ahajournals.org?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the download from http://ahajournals.org?. ### Response: April 28, 2023.


Instruction: What is the name of the system used for grading quality of evidence?

Output: GRADE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the system used for grading quality of evidence?. ### Response: GRADE.


Instruction: What is PICOM format for clinical questions and systematic review topics?

Output: S68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PICOM format for clinical questions and systematic review topics?. ### Response: S68.


Instruction: What does KDIGO nomenclature and description for grading recommendations do?

Output: grading quality of evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does KDIGO nomenclature and description for grading recommendations do?. ### Response: grading quality of evidence.


Instruction: What does Table 6 determine about the strength of recommendations?

Output: Determinants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Table 6 determine about the strength of recommendations?. ### Response: Determinants.


Instruction: What is used in select RCTs and prospective observationalstudies?

Output: measurement method and device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used in select RCTs and prospective observationalstudies?. ### Response: measurement method and device.


Instruction: What is the goal of the SPRINT research treatment algorithm for the intensive group (goal SBP 120mm Hg)?

Output: <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of the SPRINT research treatment algorithm for the intensive group (goal SBP 120mm Hg)?. ### Response: <120 mm Hg.


Instruction: How many mm Hg is in a typical CKD patient?

Output: £120

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mm Hg is in a typical CKD patient?. ### Response: £120.


Instruction: What is a CCB versus placebo/no treatment for the outcome of graft loss?

Output: Cardiovascular events in patients with CKD G3 –G4, A3 without diabetesS56 Figure 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a CCB versus placebo/no treatment for the outcome of graft loss?. ### Response: Cardiovascular events in patients with CKD G3 –G4, A3 without diabetesS56 Figure 7.


Instruction: Where is the search strategy for systematic review topics?

Output: Table S1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the search strategy for systematic review topics?. ### Response: Table S1.


Instruction: Search strategies for systematic review topicsAppendix B. Concurrence with Institute of Medicine standards for guideline developmentTable S2. Guideline development checklist –IOM standards for development of trustworthy clinical practiceguidelinesTable S3. Adapted systematic review reporting standards checklist Appendix C.

Output: diagramSUPPLEMENTARY MATERIALSupplementary File (PDF)Appendix A. Search strategiesTable S1. Search strategies for systematic review topicsAppendix B. Concurrence with Institute of Medicine (IOM) standards for guideline developmentTable S2. Guideline development checklist –IOM standards for development of trustworthy clinical practiceguidelinesTable S3. Adapted systematic review reporting standards checklist –IOM standards for systematic reviewsAppendix C. Data supplement - Summary of ﬁ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Search strategies for systematic review topicsAppendix B. Concurrence with Institute of Medicine standards for guideline developmentTable S2. Guideline development checklist –IOM standards for development of trustworthy clinical practiceguidelinesTable S3. Adapted systematic review reporting standards checklist Appendix C.. ### Response: diagramSUPPLEMENTARY MATERIALSupplementary File (PDF)Appendix A. Search strategiesTable S1. Search strategies for systematic review topicsAppendix B. Concurrence with Institute of Medicine (IOM) standards for guideline developmentTable S2. Guideline development checklist –IOM standards for development of trustworthy clinical practiceguidelinesTable S3. Adapted systematic review reporting standards checklist –IOM standards for systematic reviewsAppendix C. Data supplement - Summary of ﬁ.


Instruction: What does SoF stand for?

Output: Summary of ﬁndings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SoF stand for?. ### Response: Summary of ﬁndings.


Instruction: What is the name of the table cited in the guideline text?

Output: Table S4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the table cited in the guideline text?. ### Response: Table S4.


Instruction: What type of diet is recommended for adults with type 1 diabetes and CKD?

Output: low-salt diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet is recommended for adults with type 1 diabetes and CKD?. ### Response: low-salt diet.


Instruction: What is the difference between a low-salt diet and a regular diet?

Output: moderately increased albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between a low-salt diet and a regular diet?. ### Response: moderately increased albuminuria.


Instruction: What type of diet is recommended for adults with diabetes and CKD with severely increased albuminuria?

Output: low-salt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet is recommended for adults with diabetes and CKD with severely increased albuminuria?. ### Response: low-salt.


Instruction: What is the recommended low-salt diet for adult with diabetes?

Output: normal-salt diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended low-salt diet for adult with diabetes?. ### Response: normal-salt diet.


Instruction: How much does a low blood pressure target cost?

Output: £120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does a low blood pressure target cost?. ### Response: £120 mm Hg.


Instruction: What is the difference in blood pressure between adults with CKD and increased proteinuria/albuminuria?

Output: low blood pressure target

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference in blood pressure between adults with CKD and increased proteinuria/albuminuria?. ### Response: low blood pressure target.


Instruction: What does low blood pressure target compare to standard diastolic blood pressure?

Output: £120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does low blood pressure target compare to standard diastolic blood pressure?. ### Response: £120 mm Hg.


Instruction: What is unclear on deactivation of implanted devices?

Output: policies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unclear on deactivation of implanted devices?. ### Response: policies.


Instruction: What are ancillary therapies called?

Output: diuretic regimes (chap ter 10 ) or domiciliary oxygen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ancillary therapies called?. ### Response: diuretic regimes (chap ter 10 ) or domiciliary oxygen.


Instruction: Who is intended to use the guideline update?

Output: All healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is intended to use the guideline update?. ### Response: All healthcare professionals.


Instruction: What are the names of the people or organisations that are used by the following people or organizations?

Output: All healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the people or organisations that are used by the following people or organizations?. ### Response: All healthcare professionals.


Instruction: What are people with chronic heart failure and their carers called?

Output: All healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are people with chronic heart failure and their carers called?. ### Response: All healthcare professionals.


Instruction: What do traditional Framingham risk factors fail to fully account for in systemic lupus erythematosus?

Output: acceler -ated atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do traditional Framingham risk factors fail to fully account for in systemic lupus erythematosus?. ### Response: acceler -ated atherosclerosis.


Instruction: Arthritis Rheum. 2001;44:2331–2337.

Output: 853

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arthritis Rheum. 2001;44:2331–2337.. ### Response: 853.


Instruction: Manzi S, Selzer F, Sutton-Tyrrell.

Output: 853. Esdaile JM, Abrahamowicz M, Grodzicky T, Li Y , Panaritis C, du Berger R, Cote R, Grover SA, Fortin PR, Clarke AE, Senecal JL. Traditional Framingham risk factors fail to fully account for acceler -ated atherosclerosis in systemic lupus erythematosus. Arthritis Rheum. 2001;44:2331–2337. 854

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Manzi S, Selzer F, Sutton-Tyrrell.. ### Response: 853. Esdaile JM, Abrahamowicz M, Grodzicky T, Li Y , Panaritis C, du Berger R, Cote R, Grover SA, Fortin PR, Clarke AE, Senecal JL. Traditional Framingham risk factors fail to fully account for acceler -ated atherosclerosis in systemic lupus erythematosus. Arthritis Rheum. 2001;44:2331–2337. 854.


Instruction: What type of plaque is present in women with systemic lupus erythematosus?

Output: carotid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of plaque is present in women with systemic lupus erythematosus?. ### Response: carotid.


Instruction: What is the name of the disease that causes carotid plaque to form in women?

Output: systemic lupus erythematosus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes carotid plaque to form in women?. ### Response: systemic lupus erythematosus.


Instruction: When was the last issue of Arthritis Rheum published?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of Arthritis Rheum published?. ### Response: 1999.


Instruction: What is preclinical carotid atherosclerosis in patients with rheumatoid arthritis?

Output: Subclinical atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preclinical carotid atherosclerosis in patients with rheumatoid arthritis?. ### Response: Subclinical atherosclerosis.


Instruction: When did Ann Intern Med issue 144:249–256. 856?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ann Intern Med issue 144:249–256. 856?. ### Response: 2006.


Instruction: What is the name of the disease with systemic lupus erythematosus?

Output: rheumatoid arthritis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease with systemic lupus erythematosus?. ### Response: rheumatoid arthritis.


Instruction: Where did Salmon JE, Roman MJ, Davis A, Paget SA, Lockshin MD, Devereux RB, Schwartz JE and Levine DM come from?

Output: Sammaritano L, Devereux RB, Schwartz JE, Levine DM, Salmon JE. Preclinical carotid atherosclerosis in patients with rheumatoid arthritis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did Salmon JE, Roman MJ, Davis A, Paget SA, Lockshin MD, Devereux RB, Schwartz JE and Levine DM come from?. ### Response: Sammaritano L, Devereux RB, Schwartz JE, Levine DM, Salmon JE. Preclinical carotid atherosclerosis in patients with rheumatoid arthritis.


Instruction: What is systemic lupus erythematosus?

Output: atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is systemic lupus erythematosus?. ### Response: atherosclerosis.


Instruction: What is the name of the 2008 issue of Am J Med?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2008 issue of Am J Med?. ### Response: 2008.


Instruction: What are the bene fitsand risks ofdifferent strokepreventionstrategies?

Output: Patients withprosthetic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the bene fitsand risks ofdifferent strokepreventionstrategies?. ### Response: Patients withprosthetic valves.


Instruction: What are patients with AF andprosthetic valvesVKA No VKA- Death- All stroke- Ischemic stroke- Systemicembolism- Intracranial hem-orrhage (subdural,subarachnoid, andintracerebral)?

Output: different strokepreventionstrategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with AF andprosthetic valvesVKA No VKA- Death- All stroke- Ischemic stroke- Systemicembolism- Intracranial hem-orrhage (subdural,subarachnoid, andintracerebral)?. ### Response: different strokepreventionstrategies.


Instruction: What are the bene fitsand risks ofantithrombotictherapy for AFpatients undergoingurgentcardioversion?

Output: Urgent cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the bene fitsand risks ofantithrombotictherapy for AFpatients undergoingurgentcardioversion?. ### Response: Urgent cardioversion.


Instruction: What is the term for intracranial hem-orrhage (subdural,subarachnoid, andintracerebral)?

Output: Major extracranialhemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for intracranial hem-orrhage (subdural,subarachnoid, andintracerebral)?. ### Response: Major extracranialhemorrhage.


Instruction: What are thebenefits and risks ofantithrombotictherapy for AFpatients undergoing electivecardioversion?

Output: bene ﬁts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are thebenefits and risks ofantithrombotictherapy for AFpatients undergoing electivecardioversion?. ### Response: bene ﬁts.


Instruction: What is no anticoagulation - Death- All stroke- Ischemic stroke- Systemicembolism- Intracranial hem-orrhage (subdural,subarachnoid, andintracerebral)?

Output: Anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is no anticoagulation - Death- All stroke- Ischemic stroke- Systemicembolism- Intracranial hem-orrhage (subdural,subarachnoid, andintracerebral)?. ### Response: Anticoagulation.


Instruction: Who is Sepideh Amin-Hanjani?

Output: MD, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Sepideh Amin-Hanjani?. ### Response: MD, FAHA.


Instruction: Who is Mary Cushman?

Output: MD, MSc, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Mary Cushman?. ### Response: MD, MSc, FAHA.


Instruction: What is Mary G. George?

Output: MD, MSPH, FAHA*

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Mary G. George?. ### Response: MD, MSPH, FAHA*.


Instruction: Who is a member of the AHA/ASA Stroke Performance Oversight Committee?

Output: Hemphill JC 3rd, Adeoye OM, Alexander DN, Alexandrov AW, Amin-Hanjani S, Cushman M, George MG, LeRoux PD, Mayer SA, Qureshi AI, Saver JL, Schwamm LH, Sheth KN, Tirschwell D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the AHA/ASA Stroke Performance Oversight Committee?. ### Response: Hemphill JC 3rd, Adeoye OM, Alexander DN, Alexandrov AW, Amin-Hanjani S, Cushman M, George MG, LeRoux PD, Mayer SA, Qureshi AI, Saver JL, Schwamm LH, Sheth KN, Tirschwell D.


Instruction: What is available at https://www.ahajournals.org/journal/str DOI: 10.1161/STR.0000000000000171StrokeThe findings and conclusions in this manuscript are those of who?

Output: the author

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is available at https://www.ahajournals.org/journal/str DOI: 10.1161/STR.0000000000000171StrokeThe findings and conclusions in this manuscript are those of who?. ### Response: the author.


Instruction: Who does not necessarily represent the official position of the Centers for Disease Control and Prevention?

Output: the author

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who does not necessarily represent the official position of the Centers for Disease Control and Prevention?. ### Response: the author.


Instruction: What does the American Heart Association make every effort to avoid?

Output: any actual or potential conflicts of interest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American Heart Association make every effort to avoid?. ### Response: any actual or potential conflicts of interest.


Instruction: What is required of all members of the writing group?

Output: complete and submit a Disclosure Questionnaire

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required of all members of the writing group?. ### Response: complete and submit a Disclosure Questionnaire.


Instruction: What does the Disclosure Questionnaire show?

Output: all such relationships that might be perceived as real or potential conflicts of interest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Disclosure Questionnaire show?. ### Response: all such relationships that might be perceived as real or potential conflicts of interest.


Instruction: What is the name of the committee that approved the performance measure report?

Output: American Heart Association Science Advisory and Coordinating Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that approved the performance measure report?. ### Response: American Heart Association Science Advisory and Coordinating Committee.


Instruction: When was the American Heart Association Science Advisory and Coordinating Committee approved?

Output: January 16, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the American Heart Association Science Advisory and Coordinating Committee approved?. ### Response: January 16, 2018.


Instruction: What is a copy of the document at http://professional.heart.org?

Output: statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a copy of the document at http://professional.heart.org?. ### Response: statements.


Instruction: What is the name of the document that is available at http://professional.heart.org/statements?

Output: A copy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that is available at http://professional.heart.org/statements?. ### Response: A copy.


Instruction: How can you search for guidelines & statements?

Output: drop-down menu

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can you search for guidelines & statements?. ### Response: drop-down menu.


Instruction: What is a Data Supplement?

Output: available with this article

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Data Supplement?. ### Response: available with this article.


Instruction: What organization requests that this document be cited?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What organization requests that this document be cited?. ### Response: American Heart Association.


Instruction: What is the name of the AHA/ASA Stroke Performance Oversight Committee?

Output: American Heart Association, Inc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the AHA/ASA Stroke Performance Oversight Committee?. ### Response: American Heart Association, Inc.


Instruction: What does the AHA/ASA Stroke Performance Oversight Committee do?

Output: Clinical performance measures for adults hospitalized with intracerebral hemorrhage: performance measures for healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the AHA/ASA Stroke Performance Oversight Committee do?. ### Response: Clinical performance measures for adults hospitalized with intracerebral hemorrhage: performance measures for healthcare professionals.


Instruction: What are the performance measures for adults hospitalized with intracerebral hemorrhage?

Output: performance measures for healthcare professionals from the American Heart Association/American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the performance measures for adults hospitalized with intracerebral hemorrhage?. ### Response: performance measures for healthcare professionals from the American Heart Association/American Stroke Association.


Instruction: Who conducts the peer review of AHA-commissioned documents?

Output: AHA Office of Science Operations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who conducts the peer review of AHA-commissioned documents?. ### Response: AHA Office of Science Operations.


Instruction: Where is the AHA Office of Science Operations located?

Output: 10.1161/STR.0000000000000171Stroke*The findings and conclusions in this manuscript are those of the author and do not necessarily represent the official position of the Centers for Disease Control and Prevention.The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest.This performance measure report was approved by the American Heart Association Science Advisory and Coordinating Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the AHA Office of Science Operations located?. ### Response: 10.1161/STR.0000000000000171Stroke*The findings and conclusions in this manuscript are those of the author and do not necessarily represent the official position of the Centers for Disease Control and Prevention.The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest.This performance measure report was approved by the American Heart Association Science Advisory and Coordinating Committee.


Instruction: Where can you find more information on AHA statements and guidelines development?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find more information on AHA statements and guidelines development?. ### Response: http://professional.heart.org/statements.


Instruction: What is not permitted?

Output: Multiple copies, modification, alteration, enhancement, and/or distribution of this document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not permitted?. ### Response: Multiple copies, modification, alteration, enhancement, and/or distribution of this document.


Instruction: What is not permitted without the express permission of the author?

Output: Multiple copies, modification, alteration, enhancement, and/or distribution of this document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not permitted without the express permission of the author?. ### Response: Multiple copies, modification, alteration, enhancement, and/or distribution of this document.


Instruction: What is the name of the person who may alter, enhance, or distribute this document?

Output: author

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who may alter, enhance, or distribute this document?. ### Response: author.


Instruction: What is the standard for imaging dur -ing MR surgery?

Output: Intraoperative TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the standard for imaging dur -ing MR surgery?. ### Response: Intraoperative TEE.


Instruction: What may give the surgeon a better understanding of the valve before the operative incision?

Output: Three-dimensional TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may give the surgeon a better understanding of the valve before the operative incision?. ### Response: Three-dimensional TEE.


Instruction: What is a three-dimensional TEE?

Output: surgical view

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a three-dimensional TEE?. ### Response: surgical view.


Instruction: What does TEE mean?

Output: surgical view

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does TEE mean?. ### Response: surgical view.


Instruction: Why is TEE helpful?

Output: to evaluate the mitral valve apparatus and LV function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is TEE helpful?. ### Response: to evaluate the mitral valve apparatus and LV function.


Instruction: What should be evaluated at the same loading conditions as occurred during the awake state?

Output: deci-sions about severity of MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be evaluated at the same loading conditions as occurred during the awake state?. ### Response: deci-sions about severity of MR.


Instruction: What is especially helpful in gauging the adequacy of repair?

Output: Intraoperative TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is especially helpful in gauging the adequacy of repair?. ### Response: Intraoperative TEE.


Instruction: What is particularly helpful in gauging the adequacy of repair?

Output: Intraoperative TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is particularly helpful in gauging the adequacy of repair?. ### Response: Intraoperative TEE.


Instruction: Because even mild residual MR after repair increases the likelihood of later repair failure, surgeons strive for near-perfect what?

Output: operative repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Because even mild residual MR after repair increases the likelihood of later repair failure, surgeons strive for near-perfect what?. ### Response: operative repair.


Instruction: Adequacy is judged by TEE after physiological filling pressure and blood pressure have been established?

Output: repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adequacy is judged by TEE after physiological filling pressure and blood pressure have been established?. ### Response: repair.


Instruction: What can cause systolic anterior leaflet motion?

Output: underfilling of the LV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can cause systolic anterior leaflet motion?. ### Response: underfilling of the LV.


Instruction: What can happen if more than trivial MR is detected after repair?

Output: repair revision usually ensues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can happen if more than trivial MR is detected after repair?. ### Response: repair revision usually ensues.


Instruction: What is helpful in determining the feasibility of transcatheter edge-to-edge repair in patients with primary severe MR who are at high surgical risk?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is helpful in determining the feasibility of transcatheter edge-to-edge repair in patients with primary severe MR who are at high surgical risk?. ### Response: TEE.


Instruction: What is indicated to evaluate the mitral valve apparatus in patients with primary MR?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated to evaluate the mitral valve apparatus in patients with primary MR?. ### Response: TTE.


Instruction: What is the Online Data Supplement 26.COR LOE Recommendation1 B-NR1.

Output: Referenced studies that support the recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Online Data Supplement 26.COR LOE Recommendation1 B-NR1.. ### Response: Referenced studies that support the recommendation.


Instruction: What is TTE indicated to evaluate?

Output: mitral valve apparatus and LV function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TTE indicated to evaluate?. ### Response: mitral valve apparatus and LV function.


Instruction: What provides clinical relevant information about patients who are being followed for primary MR who develop new-onset symptoms?

Output: A repeat TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides clinical relevant information about patients who are being followed for primary MR who develop new-onset symptoms?. ### Response: A repeat TTE.


Instruction: What is the risk of MR Mild mitral valve prolapse with normal coaptation?

Output: Moderate to severe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of MR Mild mitral valve prolapse with normal coaptation?. ### Response: Moderate to severe.


Instruction: How much LA on Doppler is MR jet or small central jet area 20%?

Output: <20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much LA on Doppler is MR jet or small central jet area 20%?. ### Response: <20%.


Instruction: Progressive MR Moderate to severe mitral venous prolapse?

Output: with normal coaptation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Progressive MR Moderate to severe mitral venous prolapse?. ### Response: with normal coaptation.


Instruction: What valve changes with leaflet restriction and loss of central coaptation can cause mitral valve prolapse?

Output: Rheumatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What valve changes with leaflet restriction and loss of central coaptation can cause mitral valve prolapse?. ### Response: Rheumatic.


Instruction: What type of valve changes are most common?

Output: Rheumatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve changes are most common?. ### Response: Rheumatic.


Instruction: How much LA enlargement is there?

Output: 1+ to 2+Mild

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much LA enlargement is there?. ### Response: 1+ to 2+Mild.


Instruction: What is the normal pulmonary pressure?

Output: NoneC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the normal pulmonary pressure?. ### Response: NoneC.


Instruction: Asymptomatic severe?

Output: NoneC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Asymptomatic severe?. ### Response: NoneC.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett et al.


Instruction: What is the name of the guideline published by ACC and AHA?

Output: Guideline on the Primary Prevention of Cardiovascular Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline published by ACC and AHA?. ### Response: Guideline on the Primary Prevention of Cardiovascular Disease.


Instruction: When did Arnett publish his guideline?

Output: September 10, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Arnett publish his guideline?. ### Response: September 10, 2019.


Instruction: How many people died from coronary artery calcification?

Output: 48

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people died from coronary artery calcification?. ### Response: 48.


Instruction: How does CAC score improve coronary and CV risk assessment?

Output: above statin indication by ESC and AHA/ACC primary prevention guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does CAC score improve coronary and CV risk assessment?. ### Response: above statin indication by ESC and AHA/ACC primary prevention guidelines.


Instruction: What is the JACC Cardiovasc Imaging's 2017/10:143-53?

Output: S4.3-49

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JACC Cardiovasc Imaging's 2017/10:143-53?. ### Response: S4.3-49.


Instruction: What is the name of the multi-ethnic study of atherosclerosis?

Output: MESA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-ethnic study of atherosclerosis?. ### Response: MESA.


Instruction: What does HNR stand for?

Output: Heinz Nixdorf Recall

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HNR stand for?. ### Response: Heinz Nixdorf Recall.


Instruction: What is another name for the HNR study?

Output: Heinz Nixdorf Recall

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the HNR study?. ### Response: Heinz Nixdorf Recall.


Instruction: What is the name of the Dallas Heart Study?

Output: DHS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Dallas Heart Study?. ### Response: DHS.


Instruction: When was the J Am Coll Cardiol 66:1643-53. S4.3-50.

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 66:1643-53. S4.3-50.. ### Response: 2015.


Instruction: When did the JAMA issue 314:134-41?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the JAMA issue 314:134-41?. ### Response: 2015.


Instruction: What is the role of C-reactive protein and coronary artery calcium in risk stratification?

Output: primary prevention of coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of C-reactive protein and coronary artery calcium in risk stratification?. ### Response: primary prevention of coronary artery disease.


Instruction: What is a key factor in the prevention of coronary heart disease?

Output: C-reactive protein and coronary artery calcium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key factor in the prevention of coronary heart disease?. ### Response: C-reactive protein and coronary artery calcium.


Instruction: Who is the author of Risk stratification for primary prevention?

Output: Yeboah J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Risk stratification for primary prevention?. ### Response: Yeboah J.


Instruction: What is the Jackson Heart Study?

Output: Subclinical atherosclero-sis, statin eligibility, and outcomes in African American individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Jackson Heart Study?. ### Response: Subclinical atherosclero-sis, statin eligibility, and outcomes in African American individuals.


Instruction: What are the outcomes in African American individuals?

Output: Subclinical atherosclero-sis, statin eligibility, and outcomes in African American individuals: the Jackson Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes in African American individuals?. ### Response: Subclinical atherosclero-sis, statin eligibility, and outcomes in African American individuals: the Jackson Heart Study.


Instruction: When did the St Francis Heart Study take place?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the St Francis Heart Study take place?. ### Response: 2016.


Instruction: What is the St Francis Heart Study?

Output: Collective impact of conventional cardiovascular risk factors and coronary calcium score on clinical out-comes with or without statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the St Francis Heart Study?. ### Response: Collective impact of conventional cardiovascular risk factors and coronary calcium score on clinical out-comes with or without statin therapy.


Instruction: What are nontraditional risk markers in individuals ineligible for statin therapy according to the 2013 American College of Cardiology/American Heart Association cholesterol guidelines?

Output: Utility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are nontraditional risk markers in individuals ineligible for statin therapy according to the 2013 American College of Cardiology/American Heart Association cholesterol guidelines?. ### Response: Utility.


Instruction: What is the name of the journal that published guidelines on cardiovascular disease risk assessment?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published guidelines on cardiovascular disease risk assessment?. ### Response: JAMA.


Instruction: What are the names of the authors of the guidelines for cardiovascular disease?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the guidelines for cardiovascular disease?. ### Response: Arnett et al.


Instruction: How is the use of nontraditional risk markers compared to traditional risk markers?

Output: Utility of nontraditional risk markers in individuals ineligible for statin therapy according to the 2013 American College of Cardiology/American Heart Association cholesterol guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the use of nontraditional risk markers compared to traditional risk markers?. ### Response: Utility of nontraditional risk markers in individuals ineligible for statin therapy according to the 2013 American College of Cardiology/American Heart Association cholesterol guidelines.


Instruction: When did Krumholz HM publish his research on the treatment of cholesterol?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Krumholz HM publish his research on the treatment of cholesterol?. ### Response: 2017.


Instruction: What is the role of the clinician-patient for atherosclerotic cardiovascular disease prevention?

Output: risk discus-sion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of the clinician-patient for atherosclerotic cardiovascular disease prevention?. ### Response: risk discus-sion.


Instruction: What are the 2013 ACC/AHA guidelines?

Output: cholesterol guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2013 ACC/AHA guidelines?. ### Response: cholesterol guidelines.


Instruction: When did the J Am Coll Cardiol. 2015 65:1361–8.

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol. 2015 65:1361–8.. ### Response: 2015.


Instruction: What is a family history for?

Output: coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a family history for?. ### Response: coronary heart disease.


Instruction: What is a positive family history for coronary heart disease in patients with a zero coronary artery calcium score?

Output: posi-tive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a positive family history for coronary heart disease in patients with a zero coronary artery calcium score?. ### Response: posi-tive.


Instruction: What is the Multi-Ethnic Study of Atherosclerosis?

Output: MESA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Multi-Ethnic Study of Atherosclerosis?. ### Response: MESA.


Instruction: What is a Scientific statement from the American Heart Association?

Output: Use of nonsteroidalantiinflammatory drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Scientific statement from the American Heart Association?. ### Response: Use of nonsteroidalantiinflammatory drugs.


Instruction: What are the guidelines for the management of patients with unstable angina?

Output: 2007guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American Collegeof Cardiology/American Heart Association Task Force on PracticeGuidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the guidelines for the management of patients with unstable angina?. ### Response: 2007guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American Collegeof Cardiology/American Heart Association Task Force on PracticeGuidelines.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on PracticeGuidelines do?

Output: Writing Committee to Revise the 2002 Guidelines for theManagement of Patients With Unstable Angina/Non-ST-ElevationMyocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on PracticeGuidelines do?. ### Response: Writing Committee to Revise the 2002 Guidelines for theManagement of Patients With Unstable Angina/Non-ST-ElevationMyocardial Infarction.