Instruction: What is the effect of routine, early invasive management on outcome for elderly patients with non-ST-segment elevation acute coronary syndromes?

Output: Excess dosing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of routine, early invasive management on outcome for elderly patients with non-ST-segment elevation acute coronary syndromes?. ### Response: Excess dosing.


Instruction: When did Ann Intern Med. 2004:141:186–95?

Output: 520

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ann Intern Med. 2004:141:186–95?. ### Response: 520.


Instruction: What is age-related pharmacokinetic and pharmacdynamic changes and related risk of adverse drug reactions?

Output: 520

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is age-related pharmacokinetic and pharmacdynamic changes and related risk of adverse drug reactions?. ### Response: 520.


Instruction: What is the age-related change in pharmacodynamics focused on?

Output: drugs acting on central nervous and cardiovascular systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age-related change in pharmacodynamics focused on?. ### Response: drugs acting on central nervous and cardiovascular systems.


Instruction: What are the two main areas of focus for drugs acting on central nervous and cardiovascular systems?

Output: Age-related changes in pharmacodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two main areas of focus for drugs acting on central nervous and cardiovascular systems?. ### Response: Age-related changes in pharmacodynamics.


Instruction: What are antiplatelet and antithrombin agents used for in the treatment of non-ST-segment elevation acute coronary syndromes?

Output: Excess dosing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are antiplatelet and antithrombin agents used for in the treatment of non-ST-segment elevation acute coronary syndromes?. ### Response: Excess dosing.


Instruction: What is the name of the systematic review of prognostic indices for older adults?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of prognostic indices for older adults?. ### Response: JAMA.


Instruction: Who is Fenning S, Woolcock R, Haga K?

Output: Fenning S, Woolcock R, Haga K, et al. Identifying acute coronary syn-drome patients approaching end-of-life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Fenning S, Woolcock R, Haga K?. ### Response: Fenning S, Woolcock R, Haga K, et al. Identifying acute coronary syn-drome patients approaching end-of-life.


Instruction: What does Fenning S, Woolcock R, Haga K, et al. identify as acute coronary syn-drome patients approaching end-of-life?

Output: PLoS One

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Fenning S, Woolcock R, Haga K, et al. identify as acute coronary syn-drome patients approaching end-of-life?. ### Response: PLoS One.


Instruction: What does Tinetti ME, Bogardus ST Jr., Agostini JV do?

Output: Identifying acute coronary syn-drome patients approaching end-of-life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Tinetti ME, Bogardus ST Jr., Agostini JV do?. ### Response: Identifying acute coronary syn-drome patients approaching end-of-life.


Instruction: What is the name of the ACUITY trial?

Output: Acute Catheterization and Urgent Intervention Triage Strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACUITY trial?. ### Response: Acute Catheterization and Urgent Intervention Triage Strategy.


Instruction: What is a term for Acute Catheterization and Urgent Intervention Triage Strategy?

Output: ACUITY

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for Acute Catheterization and Urgent Intervention Triage Strategy?. ### Response: ACUITY.


Instruction: How long does bivalirudin last in octogenarians under percutaneous coronary intervention?

Output: six-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does bivalirudin last in octogenarians under percutaneous coronary intervention?. ### Response: six-month.


Instruction: When did Catheter Cardiovasc Interv. 2009:74:428–35?

Output: 528

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Catheter Cardiovasc Interv. 2009:74:428–35?. ### Response: 528.


Instruction: What is the name of the drug used to treat in-hospital bleeding and six-month outcomes?

Output: bivalirudin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat in-hospital bleeding and six-month outcomes?. ### Response: bivalirudin.


Instruction: What is the name of the preliminary study that evaluated the feasibility and safety of transradial approach and bivalirudin treatment in elderly patients?

Output: The OLDER Research Project

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the preliminary study that evaluated the feasibility and safety of transradial approach and bivalirudin treatment in elderly patients?. ### Response: The OLDER Research Project.


Instruction: What was the title of this preliminary study?

Output: The OLDER Research Project

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of this preliminary study?. ### Response: The OLDER Research Project.


Instruction: When was the J Cardiovasc Med (Hagerstown) published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Cardiovasc Med (Hagerstown) published?. ### Response: 2012.


Instruction: What is the name of the systematic review and meta-analysis of coronary revas-cularization procedures in octogenarians?

Output: Prognostic indices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis of coronary revas-cularization procedures in octogenarians?. ### Response: Prognostic indices.


Instruction: What does IMPACT stand for?

Output: Improving Addiction Care Team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does IMPACT stand for?. ### Response: Improving Addiction Care Team.


Instruction: What is the name of the randomized clinical trial of Buprenorphine?

Output: JAMA Intern Med.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial of Buprenorphine?. ### Response: JAMA Intern Med..


Instruction: What is the J Hosp Med. 2017:12:339–42?

Output: Planning and designing the Improving Addiction Care Team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Hosp Med. 2017:12:339–42?. ### Response: Planning and designing the Improving Addiction Care Team.


Instruction: When was a study of statewide discharge data conducted?

Output: 2007 to 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a study of statewide discharge data conducted?. ### Response: 2007 to 2017.


Instruction: What is the name of the 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines?

Output: Whitlock RP , Sun JC, Fremes SE, et al. Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines?. ### Response: Whitlock RP , Sun JC, Fremes SE, et al. Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis.


Instruction: How many pages were in the book Antithrombotic Therapy and Prevention of Thrombosis?

Output: 9th

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages were in the book Antithrombotic Therapy and Prevention of Thrombosis?. ### Response: 9th.


Instruction: What is the cause of infective endocarditis due to Staph-ylococcus aureus?

Output: deleterious effect of anticoagulant therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of infective endocarditis due to Staph-ylococcus aureus?. ### Response: deleterious effect of anticoagulant therapy.


Instruction: What is a deleterious effect of anticoagulant therapy?

Output: Infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a deleterious effect of anticoagulant therapy?. ### Response: Infective endocarditis.


Instruction: What is an example of anticoagulant therapy in prosthetic valve endocar-ditis?

Output: Staph-ylococcus aureus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of anticoagulant therapy in prosthetic valve endocar-ditis?. ### Response: Staph-ylococcus aureus.


Instruction: What is the name of the disease that causes intracranial hemorrhage and infarction in anticoagulated patients with prosthetic heart valves?

Output: endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes intracranial hemorrhage and infarction in anticoagulated patients with prosthetic heart valves?. ### Response: endocarditis.


Instruction: In what year was Stroke published?

Output: 1984

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was Stroke published?. ### Response: 1984.


Instruction: What is the name of the disease that causes heart valves to rupture?

Output: infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes heart valves to rupture?. ### Response: infective endocarditis.


Instruction: How long can warfarin therapy be withheld in prosthetic valves?

Output: How safely and for how long

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long can warfarin therapy be withheld in prosthetic valves?. ### Response: How safely and for how long.


Instruction: What is one of the complications associated with anticoagulant therapy?

Output: central nervous system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the complications associated with anticoagulant therapy?. ### Response: central nervous system.


Instruction: When did Circulation issue 57:1004–7?

Output: 1978

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation issue 57:1004–7?. ### Response: 1978.


Instruction: How long can warfarin therapy be withheld in prosthetic heart valve patients?

Output: How safely

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long can warfarin therapy be withheld in prosthetic heart valve patients?. ### Response: How safely.


Instruction: Chest. 2001;119:478–84.

Output: 18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chest. 2001;119:478–84.. ### Response: 18.


Instruction: Snygg-Martin U, Gustafsson L, Rosengren L, et al. Cerebrovascular complications in patients with left-sided infective endocarditis are common?

Output: 18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Snygg-Martin U, Gustafsson L, Rosengren L, et al. Cerebrovascular complications in patients with left-sided infective endocarditis are common?. ### Response: 18.


Instruction: What is the name of the prospective study using magnetic resonance imaging and neurochemical brain damage markers?

Output: Cerebrovascular com-plications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study using magnetic resonance imaging and neurochemical brain damage markers?. ### Response: Cerebrovascular com-plications.


Instruction: What are the names of the two groups that study the brain hemorrhage and manage-ment options of embolic stroke?

Output: Cerebral Embolism Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the two groups that study the brain hemorrhage and manage-ment options of embolic stroke?. ### Response: Cerebral Embolism Study Group.


Instruction: What is the name of the group that studied embolism?

Output: Cerebral Embolism Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studied embolism?. ### Response: Cerebral Embolism Study Group.


Instruction: When was Stroke.15:779–89?

Output: 1984

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Stroke.15:779–89?. ### Response: 1984.


Instruction: What is a survey of infectious disease specialists and cardiologists about?

Output: Anticoagulation in infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a survey of infectious disease specialists and cardiologists about?. ### Response: Anticoagulation in infective endocarditis.


Instruction: What is endocarditis?

Output: drug use-associated infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is endocarditis?. ### Response: drug use-associated infective endocarditis.


Instruction: What is the status of the heart?

Output: Prosthetic valve endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the status of the heart?. ### Response: Prosthetic valve endocarditis.


Instruction: When did Clin Invest. 2012 release?

Output: 2:803–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Clin Invest. 2012 release?. ### Response: 2:803–.


Instruction: How did Thuny F, Avierinos J-F, Tribouilloy C, et al. impact of cerebrovascular complications on mortality and neurologic outcome?

Output: Impact of cerebrovascular com-plications on mortality and neurologic outcome during infective endocar -ditis: a prospective multicentre study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Thuny F, Avierinos J-F, Tribouilloy C, et al. impact of cerebrovascular complications on mortality and neurologic outcome?. ### Response: Impact of cerebrovascular com-plications on mortality and neurologic outcome during infective endocar -ditis: a prospective multicentre study.


Instruction: What would be appropriate in the case of noninfarct artery stenosis?

Output: stress imaging to localize ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be appropriate in the case of noninfarct artery stenosis?. ### Response: stress imaging to localize ischemia.


Instruction: Exercise test-ing early after STEMI may also be performed to assess what?

Output: 1) assess

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise test-ing early after STEMI may also be performed to assess what?. ### Response: 1) assess.


Instruction: Who assumes any liability for injury and/or damage to persons or property?

Output: Kidney Foundation (KDIGO Managing Agent) nor the authors, contributors, or editors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who assumes any liability for injury and/or damage to persons or property?. ### Response: Kidney Foundation (KDIGO Managing Agent) nor the authors, contributors, or editors.


Instruction: What is Kidney International Supplements (2012)?

Output: 2, 337 337

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Kidney International Supplements (2012)?. ### Response: 2, 337 337.


Instruction: What is the name of the publication that was published by Kidney International Supplements in 2012?

Output: Kidney Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the publication that was published by Kidney International Supplements in 2012?. ### Response: Kidney Foundation.


Instruction: What is the date of the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction?

Output: June 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the date of the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction?. ### Response: June 2020.


Instruction: Why are there no evidence-based recommendations for patients under 40?

Output: there is no evidence for the benefit of lipid screening and treatment within this age group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are there no evidence-based recommendations for patients under 40?. ### Response: there is no evidence for the benefit of lipid screening and treatment within this age group.


Instruction: Why is there no evidence for the benefit of lipid screening and treatment within this age group?

Output: There are no evidence -based recommendations for patients under age 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there no evidence for the benefit of lipid screening and treatment within this age group?. ### Response: There are no evidence -based recommendations for patients under age 40.


Instruction: What is recommended in patients younger than 40 years old interested in pursuing lipid testing and management?

Output: shared decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients younger than 40 years old interested in pursuing lipid testing and management?. ### Response: shared decision making.


Instruction: What is recommended to discuss the risks and unknown benefit of pharmacotherapy?

Output: shared decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to discuss the risks and unknown benefit of pharmacotherapy?. ### Response: shared decision making.


Instruction: What is the primary focus of CVD primary prevention?

Output: therapeutic lifestyle changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary focus of CVD primary prevention?. ### Response: therapeutic lifestyle changes.


Instruction: Suggest regular aerobic activity of any intensity or duration of what?

Output: VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Suggest regular aerobic activity of any intensity or duration of what?. ### Response: VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction.


Instruction: What is associated with increased doses of physical activity?

Output: incremental benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with increased doses of physical activity?. ### Response: incremental benefit.


Instruction: What are lower doses associated with when compared to mostly sedentary behavior?

Output: benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are lower doses associated with when compared to mostly sedentary behavior?. ### Response: benefit.


Instruction: A provider’s considerations when recommending physical activity might include what?

Output: a patient’s motivation, functional capacity, and p hysical activity preferences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A provider’s considerations when recommending physical activity might include what?. ### Response: a patient’s motivation, functional capacity, and p hysical activity preferences.


Instruction: What is a patient's motivation, functional capacity, and p hysical activity preferences?

Output: A provider’s considerations when recommending physical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a patient's motivation, functional capacity, and p hysical activity preferences?. ### Response: A provider’s considerations when recommending physical activity.


Instruction: What is the acronym for acute coronary syndrome?

Output: ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for acute coronary syndrome?. ### Response: ACS.


Instruction: What is MI?

Output: myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MI?. ### Response: myocardial infarction.


Instruction: What is PCI?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PCI?. ### Response: percutaneous coronary intervention.


Instruction: What does multislice computed tomography do in suspected ac utecoronary syndrome?

Output: plaque morphology on multislice comput edtomography versus coronary calcium score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does multislice computed tomography do in suspected ac utecoronary syndrome?. ### Response: plaque morphology on multislice comput edtomography versus coronary calcium score.


Instruction: What is the difference between plaque morphology and coronary calcium score?

Output: multislice comput edtomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between plaque morphology and coronary calcium score?. ### Response: multislice comput edtomography.


Instruction: When was the J Am Coll Cardiol 52:216–22.223 published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 52:216–22.223 published?. ### Response: 2008.


Instruction: What type of computed tomography was used to evaluate a chest pain syndrome?

Output: 64-slice cardiac multidetector

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of computed tomography was used to evaluate a chest pain syndrome?. ### Response: 64-slice cardiac multidetector.


Instruction: What is the name of the consensus panel report on CMR?

Output: Higgins CB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the consensus panel report on CMR?. ### Response: Higgins CB.


Instruction: What is a meta-analysis of diagnostic performance of coronary magnetic resonance angiography compared to conventional X-ray angisography?

Output: Consensus Panel report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of diagnostic performance of coronary magnetic resonance angiography compared to conventional X-ray angisography?. ### Response: Consensus Panel report.


Instruction: What is the name of the study used for the detection of coronary stenoses?

Output: Coronary magnetic resonanceangiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study used for the detection of coronary stenoses?. ### Response: Coronary magnetic resonanceangiography.


Instruction: When did Kim WY, Danias PG, Stuber M, and Ioannidis JP publish?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Kim WY, Danias PG, Stuber M, and Ioannidis JP publish?. ### Response: 2004.


Instruction: What is a meta-analysis of X-ray angiography?

Output: Diagnostic performance ofcoronary magnetic resonance angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of X-ray angiography?. ### Response: Diagnostic performance ofcoronary magnetic resonance angiography.


Instruction: What is Sakuma H's role in Coronary CT versus MRangiographies?

Output: the role of MRangiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Sakuma H's role in Coronary CT versus MRangiographies?. ### Response: the role of MRangiography.


Instruction: How many patients were enrolled in a prospective study for comparison of MR and CT imaging?

Output: 117:97–102.235

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in a prospective study for comparison of MR and CT imaging?. ### Response: 117:97–102.235.


Instruction: How long does it take for patients with angina to be diagnosed in primary care?

Output: Five year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for patients with angina to be diagnosed in primary care?. ### Response: Five year.


Instruction: What is the name of the study that investigated the five year prognosis of patients with coronary artery stenosis?

Output: incident cohort study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the five year prognosis of patients with coronary artery stenosis?. ### Response: incident cohort study.


Instruction: How many people were enrolled in the incident cohort study in 2009?

Output: 230

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the incident cohort study in 2009?. ### Response: 230.


Instruction: What is a risk factor for recurrent cardiovascular disease and mortality?

Output: Kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for recurrent cardiovascular disease and mortality?. ### Response: Kidney disease.


Instruction: What is the prognostic importance ofcomorbidity for mortality in patients with stable coronary heart disease?

Output: Usefulness of type D per-sonality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic importance ofcomorbidity for mortality in patients with stable coronary heart disease?. ### Response: Usefulness of type D per-sonality.


Instruction: What is the prognostic importance of comorbidity for mortality in patients with stable coronary arterydisease?

Output: 43:576–82.233

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic importance of comorbidity for mortality in patients with stable coronary arterydisease?. ### Response: 43:576–82.233.


Instruction: What is Hlatky MA's title?

Output: Comorbidity and outcome in patients with coronary arterydisease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Hlatky MA's title?. ### Response: Comorbidity and outcome in patients with coronary arterydisease.


Instruction: What do comorbidityscores predict in patients with esta blishedcoronary artery disease?

Output: all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do comorbidityscores predict in patients with esta blishedcoronary artery disease?. ### Response: all-cause mortality.


Instruction: What is the impact of psychological factors on the pathogenesis of cardiovascular disease and implications fortherapy?

Output: Rozanski A, Blumenthal JA, Kaplan J. Impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of psychological factors on the pathogenesis of cardiovascular disease and implications fortherapy?. ### Response: Rozanski A, Blumenthal JA, Kaplan J. Impact.


Instruction: What type of per-sonality predicts five-year cardiac events above and beyond con-current symptoms of stress in patients with coronary heart disease?

Output: type D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of per-sonality predicts five-year cardiac events above and beyond con-current symptoms of stress in patients with coronary heart disease?. ### Response: type D.


Instruction: Am J Cardiol. 2006;97:970–3.237.

Output: Berkman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Am J Cardiol. 2006;97:970–3.237.. ### Response: Berkman.


Instruction: What is the effect of treat ingdepression and low perceived social support on clinical outcomes?

Output: Enhancing Recovery in Coronary HeartDisease Patients (ENRICHD) Randomized Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of treat ingdepression and low perceived social support on clinical outcomes?. ### Response: Enhancing Recovery in Coronary HeartDisease Patients (ENRICHD) Randomized Trial.


Instruction: What is the name of the randomized trial that evaluated the effects of treating ingdepression and low perceived social support?

Output: ENRICHD) Randomized Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial that evaluated the effects of treating ingdepression and low perceived social support?. ### Response: ENRICHD) Randomized Trial.


Instruction: Exercise interventions positively affect disability, aerobic fitness, mobility, and what other indices after stroke?

Output: functional balance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise interventions positively affect disability, aerobic fitness, mobility, and what other indices after stroke?. ### Response: functional balance.


Instruction: Exercise interventions are often delivered in what type of way?

Output: multimodal, lifestyle-based programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise interventions are often delivered in what type of way?. ### Response: multimodal, lifestyle-based programs.


Instruction: What type of interventions are often delivered in multimodal, lifestyle-based programs?

Output: Physical activity interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of interventions are often delivered in multimodal, lifestyle-based programs?. ### Response: Physical activity interventions.


Instruction: What is addressed in Section 6.2, Interventions Aimed at Changing Patient Behavior?

Output: Physical activity interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is addressed in Section 6.2, Interventions Aimed at Changing Patient Behavior?. ### Response: Physical activity interventions.


Instruction: How many participants were in the medical management arm of the SAMMPRIS trial?

Output: 227

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants were in the medical management arm of the SAMMPRIS trial?. ### Response: 227.


Instruction: How many primary end point events were identified at the 3-year follow-up?

Output: 49

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many primary end point events were identified at the 3-year follow-up?. ### Response: 49.


Instruction: How many ischemic strokes were identified?

Output: 32

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ischemic strokes were identified?. ### Response: 32.


Instruction: What were participants who were not in target for physical activity levels defined as?

Output: Physician-Based Assessment and Counselling for Exercise score of ≥ 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were participants who were not in target for physical activity levels defined as?. ### Response: Physician-Based Assessment and Counselling for Exercise score of ≥ 4.


Instruction: What was the Physician-Based Assessment and Counselling for Exercise score of 4?

Output: 10-minute bouts of moderate physical activity (sufficient to break a sweat or to noticeably raise heart rate, eg, walking briskly, using an exercise bicycle) up to 4 times a week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Physician-Based Assessment and Counselling for Exercise score of 4?. ### Response: 10-minute bouts of moderate physical activity (sufficient to break a sweat or to noticeably raise heart rate, eg, walking briskly, using an exercise bicycle) up to 4 times a week.


Instruction: Who had a significantly higher odds of stroke, MI, and vascular death than those who did?

Output: participants who were not in target for physical activity levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who had a significantly higher odds of stroke, MI, and vascular death than those who did?. ### Response: participants who were not in target for physical activity levels.


Instruction: What is the Physician-Based Assessment and Counselling for Exercise score?

Output: ≥ 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Physician-Based Assessment and Counselling for Exercise score?. ### Response: ≥ 4.


Instruction: How many minutes of moderate physical activity is sufficient to break a sweat or raise heart rate?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many minutes of moderate physical activity is sufficient to break a sweat or raise heart rate?. ### Response: 10.


Instruction: Up to how many times a week can one do moderate physical exercise?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Up to how many times a week can one do moderate physical exercise?. ### Response: 4.


Instruction: How many times a week can you do vigorous activity?

Output: up to twice a week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times a week can you do vigorous activity?. ### Response: up to twice a week.


Instruction: How many minutes of vigorous activity is recommended?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many minutes of vigorous activity is recommended?. ### Response: 20.


Instruction: What was the only risk factor associated with lower stroke events?

Output: physical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the only risk factor associated with lower stroke events?. ### Response: physical activity.


Instruction: Who had an OR of 6.7 (95% CI, 2.5-18.1) for recurrent stroke compared with those who achieved the targets?

Output: those who were out of target for defined physical activ-ity levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who had an OR of 6.7 (95% CI, 2.5-18.1) for recurrent stroke compared with those who achieved the targets?. ### Response: those who were out of target for defined physical activ-ity levels.


Instruction: What did multivariable analysis controlling for low-density lipoprotein, non-high-di-nt lipopolyprotein, and SBP identify?

Output: greater physi-cal activity on the Physician-Based Assessment and Counselling for Exercise scale was independently associated with 40% lower risk of stroke, MI, or vas-cular death at 3 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did multivariable analysis controlling for low-density lipoprotein, non-high-di-nt lipopolyprotein, and SBP identify?. ### Response: greater physi-cal activity on the Physician-Based Assessment and Counselling for Exercise scale was independently associated with 40% lower risk of stroke, MI, or vas-cular death at 3 years.


Instruction: What scale was associated with a 40% lower risk of stroke, MI, or vascular death at 3 years?

Output: Physician-Based Assessment and Counselling for Exercise scale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What scale was associated with a 40% lower risk of stroke, MI, or vascular death at 3 years?. ### Response: Physician-Based Assessment and Counselling for Exercise scale.


Instruction: What is a complex behavior?

Output: Physical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a complex behavior?. ### Response: Physical activity.


Instruction: The ExStroke Pilot Trial identified what type of exercise after acute ischemic stroke?

Output: Physical Exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ExStroke Pilot Trial identified what type of exercise after acute ischemic stroke?. ### Response: Physical Exercise.


Instruction: What was the name of the ExStroke Pilot Trial?

Output: Physical Exercise After Acute Ischaemic Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the ExStroke Pilot Trial?. ### Response: Physical Exercise After Acute Ischaemic Stroke.


Instruction: How long did it take to be physically active after a stroke?

Output: 2 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to be physically active after a stroke?. ### Response: 2 years.


Instruction: What did wearable activity monitors and smartphone applications demonstrate?

Output: no clear effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did wearable activity monitors and smartphone applications demonstrate?. ### Response: no clear effect.


Instruction: What did wearable activity monitors and smartphone applications not have a clear effect on in stroke settings?

Output: step count

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did wearable activity monitors and smartphone applications not have a clear effect on in stroke settings?. ### Response: step count.


Instruction: What did Wearable Activity Monitors and Smartphone Applications demonstrate no clear effect for use in conjunction with other interven-tions in stroke to improve step count?

Output: community settings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Wearable Activity Monitors and Smartphone Applications demonstrate no clear effect for use in conjunction with other interven-tions in stroke to improve step count?. ### Response: community settings.


Instruction: How many steps are needed to prevent stroke?

Output: 49

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many steps are needed to prevent stroke?. ### Response: 49.


Instruction: What is the 95% confidence interval between 40 and 2840?

Output: 1400 steps

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% confidence interval between 40 and 2840?. ### Response: 1400 steps.


Instruction: Lifestyle-based interventions for stroke secondary prevention have been identified as what?

Output: multimodal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Lifestyle-based interventions for stroke secondary prevention have been identified as what?. ### Response: multimodal.


Instruction: What are the ACC and AHA partners with?

Output: Heart Rhythm Society (HRS)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the ACC and AHA partners with?. ### Response: Heart Rhythm Society (HRS).


Instruction: What is the Society of Thoracic Surgeons a collaborator of?

Output: Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Society of Thoracic Surgeons a collaborator of?. ### Response: Heart Rhythm Society.


Instruction: Who is the focus of the clinical practice guidelines?

Output: medical practice in the United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the focus of the clinical practice guidelines?. ### Response: medical practice in the United States.


Instruction: What is the focus of the guidelines?

Output: medical practice in the United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the guidelines?. ### Response: medical practice in the United States.


Instruction: Where are the guidelines relevant to patients?

Output: throughout the world

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the guidelines relevant to patients?. ### Response: throughout the world.


Instruction: What are guidelines intended to improve?

Output: quality of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are guidelines intended to improve?. ### Response: quality of care.


Instruction: What is intended to define practices meeting the needs of patients in most but not all circumstances?

Output: Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is intended to define practices meeting the needs of patients in most but not all circumstances?. ### Response: Guidelines.


Instruction: What is effective only when followed by both practitioners and patients?

Output: Clinical ImplementationManagement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective only when followed by both practitioners and patients?. ### Response: Clinical ImplementationManagement.


Instruction: Adherence to recommen-dations can be what?

Output: enhanced by shared decision-making between clinicians and patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adherence to recommen-dations can be what?. ### Response: enhanced by shared decision-making between clinicians and patients.


Instruction: What can be enhanced by shared decision-making between clinicians and patients?

Output: Adherence to recommen-dations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be enhanced by shared decision-making between clinicians and patients?. ### Response: Adherence to recommen-dations.


Instruction: Patients engage in selecting interventions on the basis of what?

Output: individ-ual values, preferences, and associated conditions and comorbidities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients engage in selecting interventions on the basis of what?. ### Response: individ-ual values, preferences, and associated conditions and comorbidities.


Instruction: What is the Task Force on Clinical Practice Guidelines?

Output: continuously reviews, updates, and modi-fies guideline methodology on the basis of published standards from organizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Task Force on Clinical Practice Guidelines?. ### Response: continuously reviews, updates, and modi-fies guideline methodology on the basis of published standards from organizations.


Instruction: What is the Task Force on Clinical Practice Guidelines known as?

Output: Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Task Force on Clinical Practice Guidelines known as?. ### Response: Task Force.


Instruction: What does Task Force update and modi-fie guideline methodology on?

Output: published standards from organizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Task Force update and modi-fie guideline methodology on?. ### Response: published standards from organizations.


Instruction: How is presentation and delivery of guidelines reevaluated and modified?

Output: in response to evolving technologies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is presentation and delivery of guidelines reevaluated and modified?. ### Response: in response to evolving technologies.


Instruction: How are guidelines reevaluated and modified in response to evolving technologies and other factors?

Output: presentation and delivery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are guidelines reevaluated and modified in response to evolving technologies and other factors?. ### Response: presentation and delivery.


Instruction: When did numerous modifications to the guidelines begin to be implemented to make them shorter and enhance “user friendli-ness?”

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did numerous modifications to the guidelines begin to be implemented to make them shorter and enhance “user friendli-ness?”. ### Response: 2017.


Instruction: What is implemented to make guidelines shorter and enhance “user friendli-ness”?

Output: numerous modifications to the guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is implemented to make guidelines shorter and enhance “user friendli-ness”?. ### Response: numerous modifications to the guidelines.


Instruction: What format are guidelines written and presented in?

Output: modu-lar knowledge chunk format

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What format are guidelines written and presented in?. ### Response: modu-lar knowledge chunk format.


Instruction: Each chunk includes a table of recommendations, a brief synopsis, what?

Output: recommendation-specific supportive text

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Each chunk includes a table of recommendations, a brief synopsis, what?. ### Response: recommendation-specific supportive text.


Instruction: What is provided for each modular knowl-edge chunk to facilitate quick access and review?

Output: Hyper -linked references

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is provided for each modular knowl-edge chunk to facilitate quick access and review?. ### Response: Hyper -linked references.


Instruction: When will the more downloaded from http://ahajournals.org by?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the more downloaded from http://ahajournals.org by?. ### Response: April 23, 2023.


Instruction: What was the LV ejection fraction 25%?

Output: <25%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the LV ejection fraction 25%?. ### Response: <25%..


Instruction: What did carvedilol reduce the mortality risk at 12 months?

Output: 38%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did carvedilol reduce the mortality risk at 12 months?. ### Response: 38%.


Instruction: How much did the risk of death or hospitalization for HF decrease?

Output: 31%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did the risk of death or hospitalization for HF decrease?. ### Response: 31%..


Instruction: The MOCHA trial demonstrated that the effect of what is dose related?

Output: carvedilol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The MOCHA trial demonstrated that the effect of what is dose related?. ### Response: carvedilol.


Instruction: What is carvedilol's effect on LV functional and clinical superiority?

Output: dose related

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is carvedilol's effect on LV functional and clinical superiority?. ### Response: dose related.


Instruction: What is another longer-acting  -blocker?

Output: bisoprolol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another longer-acting  -blocker?. ### Response: bisoprolol.


Instruction: Bisoprolol showed similar long-term benefit on what?

Output: survival in patients with HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bisoprolol showed similar long-term benefit on what?. ### Response: survival in patients with HF.


Instruction: What study showed a 32% reduction in all-cause mortality in bisoprolol-treated patients with NYHA class III or IV HF?

Output: Cardiac Insufficiency Bisoprolol Study (CIBIS-II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study showed a 32% reduction in all-cause mortality in bisoprolol-treated patients with NYHA class III or IV HF?. ### Response: Cardiac Insufficiency Bisoprolol Study (CIBIS-II.


Instruction: At a median follow-up of 1.3 years, what was the median follow up?

Output: The Cardiac Insufficiency Bisoprolol Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At a median follow-up of 1.3 years, what was the median follow up?. ### Response: The Cardiac Insufficiency Bisoprolol Study.


Instruction: How long was the median follow-up of bisoprolol-treated patients?

Output: 1.3 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the median follow-up of bisoprolol-treated patients?. ### Response: 1.3 years.


Instruction: What was the reduction in sudden deaths in the bisoproprolol treated group?

Output: 44%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in sudden deaths in the bisoproprolol treated group?. ### Response: 44%.


Instruction: By what percentage were pump failure deaths reduced?

Output: 26%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: By what percentage were pump failure deaths reduced?. ### Response: 26%..


Instruction: Nebivolol has vasodilating properties related to what?

Output: nitric oxide modulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nebivolol has vasodilating properties related to what?. ### Response: nitric oxide modulation.


Instruction: What is SENIORS?

Output: Study of the Effects of Nebivolol Intervention on Outcomes and Rehospitalization in Seniors with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SENIORS?. ### Response: Study of the Effects of Nebivolol Intervention on Outcomes and Rehospitalization in Seniors with heart failure.


Instruction: How many patients had a history of HF, nebivolol?

Output: 2128

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had a history of HF, nebivolol?. ### Response: 2128.


Instruction: What is the 2017 VA/SCD Guideline for Circulation?

Output: e272–e391

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 VA/SCD Guideline for Circulation?. ### Response: e272–e391.


Instruction: What are the 2017 AHA/ACC/HRS guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death?

Output: Author Relationships With Industry and Other Entities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2017 AHA/ACC/HRS guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death?. ### Response: Author Relationships With Industry and Other Entities.


Instruction: What is the name of the Chair of Duke University?

Output: Sana M.  Al-Khatib

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Chair of Duke University?. ### Response: Sana M.  Al-Khatib.


Instruction: Who is the Vice Chair of Vanderbilt University Medical Center?

Output: William G. Stevenson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Chair of Vanderbilt University Medical Center?. ### Response: William G. Stevenson.


Instruction: What is William Stevenson's profession?

Output: Vice Chair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is William Stevenson's profession?. ### Response: Vice Chair.


Instruction: Who is the professor of Medicine, Pediatrics, and Pharmacology at Mayo Clinic?

Output: Michael J. Ackerman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of Medicine, Pediatrics, and Pharmacology at Mayo Clinic?. ### Response: Michael J. Ackerman.


Instruction: What is the director of Clinical Cardiac EP at Brigham and Women’s Hospital?

Output: William G. Stevenson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the director of Clinical Cardiac EP at Brigham and Women’s Hospital?. ### Response: William G. Stevenson.


Instruction: Who is the Director of the Mayo Clinic Windland Smith Rice Sudden Death Genomics Laboratory?

Output: Audentes Therapeutics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of the Mayo Clinic Windland Smith Rice Sudden Death Genomics Laboratory?. ### Response: Audentes Therapeutics.


Instruction: What is St. Jude MedicalNone None None None

Output: Boston Scientific•  Biosense Webster

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is St. Jude MedicalNone None None None. ### Response: Boston Scientific•  Biosense Webster.


Instruction: Who is an attorney at law?

Output: William J. Bryant Dominick Feld Hyde

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is an attorney at law?. ### Response: William J. Bryant Dominick Feld Hyde.


Instruction: What is the name of the company that is a member of the Transgenomic (Familion) family?

Output: Blue Ox Health Corporation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the company that is a member of the Transgenomic (Familion) family?. ### Response: Blue Ox Health Corporation.


Instruction: What is the name of the professor of medicine at the University of Pennsylvania?

Output: David J. Callans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at the University of Pennsylvania?. ### Response: David J. Callans.


Instruction: Who is the Associate Director of EP?

Output: David J. Callans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Associate Director of EP?. ### Response: David J. Callans.


Instruction: What does Endosense stand for?

Output: PI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Endosense stand for?. ### Response: PI.


Instruction: What is the name of the professor at the University of Buffalo?

Output: Anne B. Curtis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor at the University of Buffalo?. ### Response: Anne B. Curtis.


Instruction: Who is the Chair of St. Jude?

Output: Charles and Mary Bauer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of St. Jude?. ### Response: Charles and Mary Bauer.


Instruction: What is the name of the professor of cardiology at Northwestern University?

Output: Barbara J. Deal Getz

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of cardiology at Northwestern University?. ### Response: Barbara J. Deal Getz.


Instruction: Who is the Associate Professor of Cardiology at the University of Maryland?

Output: Timm Dickfeld

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Associate Professor of Cardiology at the University of Maryland?. ### Response: Timm Dickfeld.


Instruction: What is the name of the University of Maryland associate professor of medicine?

Output: Timm Dickfeld

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the University of Maryland associate professor of medicine?. ### Response: Timm Dickfeld.


Instruction: What is another name for St. Jude Medical?

Output: Boston Scientific

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for St. Jude Medical?. ### Response: Boston Scientific.


Instruction: Who is the Associate Professor of Medicine?

Output: Timm Dickfeld

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Associate Professor of Medicine?. ### Response: Timm Dickfeld.


Instruction: Who is the professor of medicine at the University of Calgary?

Output: Anne M. Gillis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of medicine at the University of Calgary?. ### Response: Anne M. Gillis.


Instruction: What is the name of the professor at Duke University?

Output: Christopher B. Granger

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor at Duke University?. ### Response: Christopher B. Granger.


Instruction: Which university is the Professor of Medicine at?

Output: University of Calgary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which university is the Professor of Medicine at?. ### Response: University of Calgary.


Instruction: What should patients do to reduce the rate of rebleeding after aSAH?

Output: repeat coiling or microsurgical clipping

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients do to reduce the rate of rebleeding after aSAH?. ### Response: repeat coiling or microsurgical clipping.


Instruction: When is complete obliteration of the aneurysm recommended?

Output: whenever possible

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is complete obliteration of the aneurysm recommended?. ### Response: whenever possible.


Instruction: What should patients who undergo coiling or clipping of a ruptured aneurysm have?

Output: delayed follow-up vascular imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients who undergo coiling or clipping of a ruptured aneurysm have?. ### Response: delayed follow-up vascular imaging.


Instruction: What should be given strong consideration to retreatment?

Output: repeat coiling or microsurgical clipping

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given strong consideration to retreatment?. ### Response: repeat coiling or microsurgical clipping.


Instruction: If there is a clinically compelling contraindication, what should patients undergo?

Output: retreatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If there is a clinically compelling contraindication, what should patients undergo?. ### Response: retreatment.


Instruction: What should low-volume hospitals consider early transfer of patients with aSAH to high-volumecenters with experienced cerebrovascular surgeons, endovascular specialists, andmultidisciplinary neuro-intensive care services?

Output: Low-volume hospitals (eg, /H1102110 aSAH cases per year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should low-volume hospitals consider early transfer of patients with aSAH to high-volumecenters with experienced cerebrovascular surgeons, endovascular specialists, andmultidisciplinary neuro-intensive care services?. ### Response: Low-volume hospitals (eg, /H1102110 aSAH cases per year.


Instruction: What is recommended to prevent DCI?

Output: Maintenance of euvolemia and normal circulating blood volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to prevent DCI?. ### Response: Maintenance of euvolemia and normal circulating blood volume.


Instruction: What is not recommended for patients with DCI unless blood pressure is elevated at baseline or cardiacstatus precludes it?

Output: Induction of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for patients with DCI unless blood pressure is elevated at baseline or cardiacstatus precludes it?. ### Response: Induction of hypertension.


Instruction: What precludes aSAH?

Output: blood pressure is elevated at baseline or cardiacstatus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What precludes aSAH?. ### Response: blood pressure is elevated at baseline or cardiacstatus.


Instruction: What should be managed by cerebrospinal fluid diversion?

Output: aSAH-associated acute symptomatic hydrocephalus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be managed by cerebrospinal fluid diversion?. ### Response: aSAH-associated acute symptomatic hydrocephalus.


Instruction: Heparin-induced thrombocytopenia and deep venousthrombosis are not uncommon after what?

Output: aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Heparin-induced thrombocytopenia and deep venousthrombosis are not uncommon after what?. ### Response: aSAH.


Instruction: Early identification and targeted treatment are recommended but what is needed?

Output: further research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Early identification and targeted treatment are recommended but what is needed?. ### Response: further research.


Instruction: What is recommended, but further research is needed to identify the idealscreening paradigms?

Output: Early identification and targeted treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended, but further research is needed to identify the idealscreening paradigms?. ### Response: Early identification and targeted treatment.


Instruction: What should be a multidisciplinary decision based on characteristics of the patient and the aneurysm?

Output: Determination of aneurysm treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be a multidisciplinary decision based on characteristics of the patient and the aneurysm?. ### Response: Determination of aneurysm treatment.


Instruction: How should aSAH-associated chronic symptomatic hydrocephalus be treated?

Output: permanent cerebrospinal fluid diversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should aSAH-associated chronic symptomatic hydrocephalus be treated?. ### Response: permanent cerebrospinal fluid diversion.


Instruction: What should be treated with aSAH-associated chronic symptomatic hydrocephalus?

Output: permanent cerebrospinal fluid diversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be treated with aSAH-associated chronic symptomatic hydrocephalus?. ### Response: permanent cerebrospinal fluid diversion.


Instruction: What indicates aneurysmal subarachnoid hemorrhage?

Output: aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates aneurysmal subarachnoid hemorrhage?. ### Response: aSAH.


Instruction: CT, computed tomography, DSA, and EVD are what?

Output: aSAH indicates aneurysmal subarachnoid hemorrhage; CT, computed tomography; DSA, digital subtraction angiography; DCI, delayed cerebral ischem ia; and EVD,external ventricular drainage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CT, computed tomography, DSA, and EVD are what?. ### Response: aSAH indicates aneurysmal subarachnoid hemorrhage; CT, computed tomography; DSA, digital subtraction angiography; DCI, delayed cerebral ischem ia; and EVD,external ventricular drainage.


Instruction: What did Connolly and al Management of Aneurysmal Subarachnoid Hemorrhage 1715Downloaded from http://ahajournals.org by on April 28, 2023?

Output: A new recommendation.†A change in either level of evidence or strength of the recommendation from previous guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Connolly and al Management of Aneurysmal Subarachnoid Hemorrhage 1715Downloaded from http://ahajournals.org by on April 28, 2023?. ### Response: A new recommendation.†A change in either level of evidence or strength of the recommendation from previous guidelines.


Instruction: What is the impact of vacuum-assisted closure on long-term survival after post-sternotomy medias-tinitis?

Output: Sjogren J, Nilsson J, Gustafsson R, et al. The impact of vacuum-assisted closure on long-term survival after post-sternotomy medias-tinitis. Ann Thorac Surg. 2005;80:1270–5.922

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of vacuum-assisted closure on long-term survival after post-sternotomy medias-tinitis?. ### Response: Sjogren J, Nilsson J, Gustafsson R, et al. The impact of vacuum-assisted closure on long-term survival after post-sternotomy medias-tinitis. Ann Thorac Surg. 2005;80:1270–5.922.


Instruction: What was the name of the project that eliminated the diabetic disadvantage: the PortlandDiabetic Project?

Output: PortlandDiabetic Project

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the project that eliminated the diabetic disadvantage: the PortlandDiabetic Project?. ### Response: PortlandDiabetic Project.


Instruction: What does continuous insulin therapy reduce postoperative supraventricular tachycardia incidence aftercoronary artery bypass operations in diabetic patients?

Output: Does continuous insulin therapyreduce postoperative supraventricular tachycardia incidence aftercoronary artery bypass operations in diabetic patients? J CardiothoracVasc Anesth. 2008;22:383–7.924

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does continuous insulin therapy reduce postoperative supraventricular tachycardia incidence aftercoronary artery bypass operations in diabetic patients?. ### Response: Does continuous insulin therapyreduce postoperative supraventricular tachycardia incidence aftercoronary artery bypass operations in diabetic patients? J CardiothoracVasc Anesth. 2008;22:383–7.924.


Instruction: What is the name of the double-blind,randomized controlled trial on the effect of leukocyte-depleted eryth-rocyte transfusions in cardiac valves?

Output: Bilgin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the double-blind,randomized controlled trial on the effect of leukocyte-depleted eryth-rocyte transfusions in cardiac valves?. ### Response: Bilgin.


Instruction: What is the effect of leukocyte-depleted eryth-rocyte transfusions in cardiac valve surgery?

Output: Double-blind,randomized controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of leukocyte-depleted eryth-rocyte transfusions in cardiac valve surgery?. ### Response: Double-blind,randomized controlled trial.


Instruction: What was the result of an implementation trial?

Output: reduced trans-fusions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of an implementation trial?. ### Response: reduced trans-fusions.


Instruction: What is the leukoreduction program for red blood cell transfusions in coronary surgery associated with?

Output: reduced acute kidney injury and in-hospital mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the leukoreduction program for red blood cell transfusions in coronary surgery associated with?. ### Response: reduced acute kidney injury and in-hospital mortality.


Instruction: What was the J Thorac Car-diovasc Surg. 2010;140:188–95.927?

Output: Leukoreduction programfor red blood cell transfusions in coronary surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Thorac Car-diovasc Surg. 2010;140:188–95.927?. ### Response: Leukoreduction programfor red blood cell transfusions in coronary surgery.


Instruction: How did leukocyte depletion of transfused blood affect postoperative complications?

Output: beneficial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did leukocyte depletion of transfused blood affect postoperative complications?. ### Response: beneficial.


Instruction: What is the effect of transfused blood on postoperative compli-cations in patients undergoing cardiac surgery?

Output: beneficial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of transfused blood on postoperative compli-cations in patients undergoing cardiac surgery?. ### Response: beneficial.


Instruction: What was the name of the randomized clinicaltrial?

Output: Double-blind,randomized controlled trial on the effect of leukocyte-depleted eryth-rocyte transfusions in cardiac valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the randomized clinicaltrial?. ### Response: Double-blind,randomized controlled trial on the effect of leukocyte-depleted eryth-rocyte transfusions in cardiac valve surgery.


Instruction: How did Konvalinka A, Errett L, Fong IW, et al. treat Staphylococcusaureus nasal carriers?

Output: wound infections in cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Konvalinka A, Errett L, Fong IW, et al. treat Staphylococcusaureus nasal carriers?. ### Response: wound infections in cardiac surgery.


Instruction: What is the name of the ointment used to prevent Staphylococcus aureus infections in nasal carriers?

Output: Mupirocin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ointment used to prevent Staphylococcus aureus infections in nasal carriers?. ### Response: Mupirocin.


Instruction: When was the CD006216.930 published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the CD006216.930 published?. ### Response: 2008.


Instruction: What is a comparative study of surgicalskin preparation methods?

Output: Surg Gynecol Obstet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparative study of surgicalskin preparation methods?. ### Response: Surg Gynecol Obstet.


Instruction: What did Kaiser AB, Kernodle DS, Barg NL, et al. influence of preoperativeshowers on staphylococcal skin colonization: a comparative trial ofantiseptic skin cleansers?

Output: 1983;157:265–8.932

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Kaiser AB, Kernodle DS, Barg NL, et al. influence of preoperativeshowers on staphylococcal skin colonization: a comparative trial ofantiseptic skin cleansers?. ### Response: 1983;157:265–8.932.


Instruction: What was the risk factor for deep sternal wound infection after sternotomy?

Output: vacuum-assisted closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk factor for deep sternal wound infection after sternotomy?. ### Response: vacuum-assisted closure.


Instruction: What is the name of the multicenter study of deep sternal wound infection after sternotomy?

Output: Risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter study of deep sternal wound infection after sternotomy?. ### Response: Risk factors.


Instruction: When was the J Thorac Cardiovasc Surg. 111:1200–7.934?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg. 111:1200–7.934?. ### Response: 1996.


Instruction: What is one of the national initiatives to improve outcomes for patients having surgery?

Output: surgicalcare improvement projects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the national initiatives to improve outcomes for patients having surgery?. ### Response: surgicalcare improvement projects.


Instruction: What did Lazenby WD, Zelano JA, et al. do after bypass oper-ations?

Output: Effects of shaving methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Lazenby WD, Zelano JA, et al. do after bypass oper-ations?. ### Response: Effects of shaving methods.


Instruction: What did Nishida H, Grooters RK, Soltanzadeh H, and al. use on the median sternotomy incision.

Output: electrocautery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Nishida H, Grooters RK, Soltanzadeh H, and al. use on the median sternotomy incision.. ### Response: electrocautery.


Instruction: What was the wound infection rate?

Output: 0.16%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the wound infection rate?. ### Response: 0.16%.


Instruction: How many exceptions does the Work Group agree that there is little evidence or likelihood of healthbene fits observed in the general population?

Output: few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many exceptions does the Work Group agree that there is little evidence or likelihood of healthbene fits observed in the general population?. ### Response: few.


Instruction: What is evidence that health benefits observed in the general population should not apply to CKD patients?

Output: little

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evidence that health benefits observed in the general population should not apply to CKD patients?. ### Response: little.


Instruction: What may be particularly beneficial in CK D patients, according to dietary sodiumreduction?

Output: lower BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be particularly beneficial in CK D patients, according to dietary sodiumreduction?. ### Response: lower BP.


Instruction: What are CKD commonly hypertensive?

Output: Persons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are CKD commonly hypertensive?. ### Response: Persons.


Instruction: What has suggested that the magnitude of BPreduction for a given degree of reduction in dietary sodiumintake is magni fied in hypertensed individuals?

Output: systematic reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has suggested that the magnitude of BPreduction for a given degree of reduction in dietary sodiumintake is magni fied in hypertensed individuals?. ### Response: systematic reviews.


Instruction: What may have a greater risk reduction of such events with dietary sodium reduction?

Output: CKD populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have a greater risk reduction of such events with dietary sodium reduction?. ### Response: CKD populations.


Instruction: ACEi and ARBs are commonly used in what?

Output: CKD patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ACEi and ARBs are commonly used in what?. ### Response: CKD patients.


Instruction: What may enhance theeffects of CKD?

Output: dietary sodiumreduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may enhance theeffects of CKD?. ### Response: dietary sodiumreduction.


Instruction: What may low-sodium intake enhance theeffects of these medications on?

Output: kidney and CV outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may low-sodium intake enhance theeffects of these medications on?. ### Response: kidney and CV outcomes.


Instruction: What is likely to be appropriate in children with CKD, although with modi fid targets?

Output: decreasing dietary sodiumintake

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to be appropriate in children with CKD, although with modi fid targets?. ### Response: decreasing dietary sodiumintake.


Instruction: What does the WorkGroup believe would be reasonable to adjust the 2g(90 mmol) dailytarget for body weight in children?

Output: Speci ﬁc targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the WorkGroup believe would be reasonable to adjust the 2g(90 mmol) dailytarget for body weight in children?. ### Response: Speci ﬁc targets.


Instruction: The Work Group considered the speci fic target of sodiumintake of what?

Output: <2g(<90 mmol) daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Work Group considered the speci fic target of sodiumintake of what?. ### Response: <2g(<90 mmol) daily.


Instruction: What was found to not be different in CKD populations per se?

Output: sodiumintake targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to not be different in CKD populations per se?. ### Response: sodiumintake targets.


Instruction: Existing studies targeting BP typicallytargeted 2go r2.3 g daily in what arms?

Output: low-sodium arms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Existing studies targeting BP typicallytargeted 2go r2.3 g daily in what arms?. ### Response: low-sodium arms.


Instruction: What should be recommended for the general popula-tion?

Output: relative bene ﬁts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be recommended for the general popula-tion?. ### Response: relative bene ﬁts.


Instruction: Why was the present guideline created in the absence of data suggesting superiority or inferiority of othertargets in CKD populations?

Output: low-to-moderate-quality evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the present guideline created in the absence of data suggesting superiority or inferiority of othertargets in CKD populations?. ### Response: low-to-moderate-quality evidence.


Instruction: a target of 2.0g per day should be recommended for CKD populations?

Output: <2g(<90 mmol) dailytarget for body weight in children

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: a target of 2.0g per day should be recommended for CKD populations?. ### Response: <2g(<90 mmol) dailytarget for body weight in children.


Instruction: studies showing that short-term dietarysodium reduction interventions lower what?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: studies showing that short-term dietarysodium reduction interventions lower what?. ### Response: BP.


Instruction: What is a non-pharmacologic intervention to lower BP in CKD populations?

Output: dietary sodium-reduction strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a non-pharmacologic intervention to lower BP in CKD populations?. ### Response: dietary sodium-reduction strategies.


Instruction: What was a relative lowervalue placed on the challenges in following a low-sodiumdiet?

Output: bene ﬁts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a relative lowervalue placed on the challenges in following a low-sodiumdiet?. ### Response: bene ﬁts.


Instruction: What is made despite low-to-moderate-quality evidence in CKDpopulations per se?

Output: the present guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is made despite low-to-moderate-quality evidence in CKDpopulations per se?. ### Response: the present guideline.


Instruction: What is an indication of severe, obstructive CAD?

Output: The development of symptomatic LV failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an indication of severe, obstructive CAD?. ### Response: The development of symptomatic LV failure.


Instruction: What type of LV failure in a patient with SIHD is often an indication?

Output: symptomatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of LV failure in a patient with SIHD is often an indication?. ### Response: symptomatic.


Instruction: What requires expeditious evaluation for the presence ofactive ischemia?

Output: The development of symptomatic LV failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What requires expeditious evaluation for the presence ofactive ischemia?. ### Response: The development of symptomatic LV failure.


Instruction: What is warranted depending on the acuity and severity ofsymptoms?

Output: angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is warranted depending on the acuity and severity ofsymptoms?. ### Response: angiography.


Instruction: What do angiographers use to estimate thepotential benefit of revascularization strategies discussed below?

Output: coronary angiography and left ventriculography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do angiographers use to estimate thepotential benefit of revascularization strategies discussed below?. ### Response: coronary angiography and left ventriculography.


Instruction: What are the characteristics of coronary lesions?

Output: stenosis severity,length, complexity, and presence of thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the characteristics of coronary lesions?. ### Response: stenosis severity,length, complexity, and presence of thrombus.


Instruction: What is a possible role of collaterals?

Output: coronary lesions (eg, stenosis severity,length, complexity, and presence of thrombus), the number oflesions posing jeopardy to regions of contracting myocardium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible role of collaterals?. ### Response: coronary lesions (eg, stenosis severity,length, complexity, and presence of thrombus), the number oflesions posing jeopardy to regions of contracting myocardium.


Instruction: What can afford some insight into the consequences of subsequent vessel occlusion?

Output: The characteristics of coronary lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can afford some insight into the consequences of subsequent vessel occlusion?. ### Response: The characteristics of coronary lesions.


Instruction: A patient with a noncontracting inferior or lateral wall and severe proximal stenosis of a very large LAD artery is presumably at substantial risk of developing what?

Output: cardiogenic shock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A patient with a noncontracting inferior or lateral wall and severe proximal stenosis of a very large LAD artery is presumably at substantial risk of developing what?. ### Response: cardiogenic shock.


Instruction: What is the risk of developing cardiogenic shock if the LADartery were to become occluded?

Output: substantial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of developing cardiogenic shock if the LADartery were to become occluded?. ### Response: substantial.


Instruction: What has been developed in view of the importance of proximal versus distal coronarystenoses?

Output: a “jeopardy score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been developed in view of the importance of proximal versus distal coronarystenoses?. ### Response: a “jeopardy score.


Instruction: What do angiographic studies indicate about the severity of CAD?

Output: a direct correlationalso exists between the angiographic severity of CAD and theamount of angiographically insignificant plaque buildup else-where in the coronary tree

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do angiographic studies indicate about the severity of CAD?. ### Response: a direct correlationalso exists between the angiographic severity of CAD and theamount of angiographically insignificant plaque buildup else-where in the coronary tree.


Instruction: What could cause a higher mortality rate in patients with multivessel disease?

Output: they have more mildly stenotic or nonstenotic plaquesthat are potential sites for acute coronary events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could cause a higher mortality rate in patients with multivessel disease?. ### Response: they have more mildly stenotic or nonstenotic plaquesthat are potential sites for acute coronary events.


Instruction: What type of plaques are more likely sites for acute coronary events than patients with 1-vessel disease?

Output: mildly stenotic or nonstenotic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of plaques are more likely sites for acute coronary events than patients with 1-vessel disease?. ### Response: mildly stenotic or nonstenotic.


Instruction: For many years, it has been known that patients with severestenosis of the left main coronary artery have a poor prognosis when treated what?

Output: medically

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For many years, it has been known that patients with severestenosis of the left main coronary artery have a poor prognosis when treated what?. ### Response: medically.


Instruction: What is poor prognosis when treated medically?

Output: patients with severestenosis of the left main coronary artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is poor prognosis when treated medically?. ### Response: patients with severestenosis of the left main coronary artery.


Instruction: What has been found with increasing degrees of stenosis of theleft main in medically managed patients?

Output: A gradation of worsening risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been found with increasing degrees of stenosis of theleft main in medically managed patients?. ### Response: A gradation of worsening risk.


Instruction: Angiographicdetermination of the significance of left main disease can be what?

Output: bedifficult

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Angiographicdetermination of the significance of left main disease can be what?. ### Response: bedifficult.


Instruction: What other modalities are available to the angiographer to assist in accurately determining the signifi-cance of a left main lesion?

Output: FFR and intravascularultrasound

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What other modalities are available to the angiographer to assist in accurately determining the signifi-cance of a left main lesion?. ### Response: FFR and intravascularultrasound.