Instruction: What is the effect of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure?

Output: Overview of randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure?. ### Response: Overview of randomized trials.


Instruction: What is ramipril?

Output: angiotensin-converting-enzyme inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ramipril?. ### Response: angiotensin-converting-enzyme inhibitor.


Instruction: When was this study published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 28, 2023.


Instruction: What should new methods and techniques involving drug usage only be followed in conjunction with the drug manufacturer’s own published literature?

Output: this Journal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should new methods and techniques involving drug usage only be followed in conjunction with the drug manufacturer’s own published literature?. ### Response: this Journal.


Instruction: Kidney International Supplements (2012) 2, 363–369chapter 4 of what journal should be followed?

Output: in conjunction with thedrug manufacturer’s own published literature

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kidney International Supplements (2012) 2, 363–369chapter 4 of what journal should be followed?. ### Response: in conjunction with thedrug manufacturer’s own published literature.


Instruction: What type of aneurysms are seen in patients with subarachnoid hemorrhage?

Output: Intracranial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of aneurysms are seen in patients with subarachnoid hemorrhage?. ### Response: Intracranial.


Instruction: What is CT angiography used for?

Output: diagnosis: systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CT angiography used for?. ### Response: diagnosis: systematic review and meta-analysis.


Instruction: What is angiogram-negative subarachnoid hemorrhage in the era of?

Output: threedimensional rotational angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is angiogram-negative subarachnoid hemorrhage in the era of?. ### Response: threedimensional rotational angiography.


Instruction: What is the J Clin Neurosci 2007:14:252–255.122?

Output: the era of threedimensional rotational angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Clin Neurosci 2007:14:252–255.122?. ### Response: the era of threedimensional rotational angiography.


Instruction: What is a negative aneurysmal sub-arachnoid hemorrhage?

Output: Angiogram

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a negative aneurysmal sub-arachnoid hemorrhage?. ### Response: Angiogram.


Instruction: What is the AJNR Am J Neuro-radiol. 2008;29:962–966.123.

Output: Additional value of3D rotational angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AJNR Am J Neuro-radiol. 2008;29:962–966.123.. ### Response: Additional value of3D rotational angiography.


Instruction: What are the initial results of clinical evaluation of?

Output: flat-panel detector

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the initial results of clinical evaluation of?. ### Response: flat-panel detector.


Instruction: What type of CT is used for visu-alization of subarachnoid hemorrhage and ventricles?

Output: conventional CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of CT is used for visu-alization of subarachnoid hemorrhage and ventricles?. ### Response: conventional CT.


Instruction: What type of CT is used for patients with subarachnoid hemorrhage?

Output: CT angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of CT is used for patients with subarachnoid hemorrhage?. ### Response: CT angiography.


Instruction: What is the name of the prospective study using a self-developing film badge?

Output: Cumulative radiation dose inpatients admitted with subarachnoid hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study using a self-developing film badge?. ### Response: Cumulative radiation dose inpatients admitted with subarachnoid hemorrhage.


Instruction: When was the last time a patient was admitted to the AJNR Am J Neuroradiol?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a patient was admitted to the AJNR Am J Neuroradiol?. ### Response: 2008.


Instruction: What is a self-developing film badge?

Output: Cumulative radiation dose inpatients admitted with subarachnoid hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a self-developing film badge?. ### Response: Cumulative radiation dose inpatients admitted with subarachnoid hemorrhage.


Instruction: When did AJNR Am J Neuroradiol publish its 31:1787–1790.127?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did AJNR Am J Neuroradiol publish its 31:1787–1790.127?. ### Response: 2010.


Instruction: What did a pro-spective randomized study show about rebleeding after aneurysmal subarachnoid hemorrhage?

Output: reduced incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a pro-spective randomized study show about rebleeding after aneurysmal subarachnoid hemorrhage?. ### Response: reduced incidence.


Instruction: What is the name of the preliminary report from the Cooperative Aneurysm Study?

Output: Aneurysmal rebleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the preliminary report from the Cooperative Aneurysm Study?. ### Response: Aneurysmal rebleeding.


Instruction: What is a predictors and impact of aneurym rebleeding after subarachnoid hemorrhage?

Output: reduced incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictors and impact of aneurym rebleeding after subarachnoid hemorrhage?. ### Response: reduced incidence.


Instruction: What causes rebleeding after subarachnoid hemorrhage?

Output: aneurysm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes rebleeding after subarachnoid hemorrhage?. ### Response: aneurysm.


Instruction: What is the name of the cooperative study in North Eastern Province ofJapan?

Output: Rebleedingfrom ruptured intracranial aneurysms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the cooperative study in North Eastern Province ofJapan?. ### Response: Rebleedingfrom ruptured intracranial aneurysms.


Instruction: What is the name of the cooperative study of aneurysms in North Eastern Province ofJapan?

Output: J Neurol Sci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the cooperative study of aneurysms in North Eastern Province ofJapan?. ### Response: J Neurol Sci.


Instruction: When was the J Neurol Sci.258:11-16.132?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Neurol Sci.258:11-16.132?. ### Response: 2007.


Instruction: What are the factors associated with clinical outcome in the rebleedingpatients?

Output: Aneurysmalrebleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the factors associated with clinical outcome in the rebleedingpatients?. ### Response: Aneurysmalrebleeding.


Instruction: What is the name of the study that was published in 2010?

Output: J Neu-rosurg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that was published in 2010?. ### Response: J Neu-rosurg.


Instruction: What was the date of publication for the study?

Output: 1180.131

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the date of publication for the study?. ### Response: 1180.131.


Instruction: How many patients with CHD face gaps in care during and after adolescence?

Output: Many

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with CHD face gaps in care during and after adolescence?. ### Response: Many.


Instruction: What are some common reasons for care during and after adolescence?

Output: lack of knowledge regarding need for follow-up, in-ability to find specialized providers, insurance issues, and feeling well

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some common reasons for care during and after adolescence?. ### Response: lack of knowledge regarding need for follow-up, in-ability to find specialized providers, insurance issues, and feeling well.


Instruction: What are patients with gaps in care more likely to develop than those receiving continuous care?

Output: medical problems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with gaps in care more likely to develop than those receiving continuous care?. ### Response: medical problems.


Instruction: What did Canadian patients with CHD in special-ized care programs have lower mortality than those in centers without ACHD expertise?

Output: S3.2-3,S3.2-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Canadian patients with CHD in special-ized care programs have lower mortality than those in centers without ACHD expertise?. ### Response: S3.2-3,S3.2-4.


Instruction: Improving transition programs and recognizing the importance of long-term care will hopefully improve what?

Output: access to specialty care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Improving transition programs and recognizing the importance of long-term care will hopefully improve what?. ### Response: access to specialty care.


Instruction: Insurance barriers and lack of what are issues?

Output: spe-cialty providers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Insurance barriers and lack of what are issues?. ### Response: spe-cialty providers.


Instruction: Relationships with regulatory agencies to address these challenges are important what?

Output: Insurance barriers and lack of spe-cialty providers for the large number of patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Relationships with regulatory agencies to address these challenges are important what?. ### Response: Insurance barriers and lack of spe-cialty providers for the large number of patients.


Instruction: What should patients with ACHD be managed in collaboration with?

Output: an ACHD cardiologist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with ACHD be managed in collaboration with?. ### Response: an ACHD cardiologist.


Instruction: What should cardiac surgery, catheter-based interventional cardiac procedures, and electrophysiological procedures involving congenital heart lesions do?

Output: should be performed by operators with expertise in CHD procedures and in collaboration with an ACHD  cardiologist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should cardiac surgery, catheter-based interventional cardiac procedures, and electrophysiological procedures involving congenital heart lesions do?. ### Response: should be performed by operators with expertise in CHD procedures and in collaboration with an ACHD  cardiologist.


Instruction: Who should perform procedures involving congenital heart lesions in patients with ACHD?

Output: operators with expertise in CHD procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should perform procedures involving congenital heart lesions in patients with ACHD?. ### Response: operators with expertise in CHD procedures.


Instruction: What should operators with expertise in CHD procedures and in collaboration with an ACHD cardiologist do?

Output: Cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should operators with expertise in CHD procedures and in collaboration with an ACHD cardiologist do?. ### Response: Cardiac surgery.


Instruction: What do patients with ACHD cared for in specialized centers have lower mortality than those managed without spe-cialized care?

Output: more severe CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients with ACHD cared for in specialized centers have lower mortality than those managed without spe-cialized care?. ### Response: more severe CHD.


Instruction: What can be helpful in making management decisions for ACHD patients?

Output: clinical practice guide-lines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be helpful in making management decisions for ACHD patients?. ### Response: clinical practice guide-lines.


Instruction: Many management decisions must be based on what?

Output: clinical practice guide-lines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Many management decisions must be based on what?. ### Response: clinical practice guide-lines.


Instruction: What must be based on insuf-ficient data or care guidelines?

Output: management decisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be based on insuf-ficient data or care guidelines?. ### Response: management decisions.


Instruction: What may patients with complex anatomic and physiological forms of ACHD need approaches that differ from those applicable to adults without ACHD?

Output: evaluation and treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients with complex anatomic and physiological forms of ACHD need approaches that differ from those applicable to adults without ACHD?. ### Response: evaluation and treatment.


Instruction: What are some examples of adults without ACHD who have valve disease, HF, or arrhythmias?

Output: Different needs for evaluation and management compared with adults with acquired cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some examples of adults without ACHD who have valve disease, HF, or arrhythmias?. ### Response: Different needs for evaluation and management compared with adults with acquired cardiovascular disease.


Instruction: What are two examples of specialties that have defined expertise in ACHD?

Output: cardi-ology and congenital heart surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two examples of specialties that have defined expertise in ACHD?. ### Response: cardi-ology and congenital heart surgery.


Instruction: What are two specialties that have defined ACHD fellowship training and board certification?

Output: cardi-ology and congenital heart surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two specialties that have defined ACHD fellowship training and board certification?. ### Response: cardi-ology and congenital heart surgery.


Instruction: What is gained by focused experience during training and practice?

Output: ACHD expertise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is gained by focused experience during training and practice?. ### Response: ACHD expertise.


Instruction: When did the American Board of Medical Spe-cialization publish a report on ACHD expertise?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the American Board of Medical Spe-cialization publish a report on ACHD expertise?. ### Response: 2012.


Instruction: What type of disease is evidence of vascular disease?

Output: pleural

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of disease is evidence of vascular disease?. ### Response: pleural.


Instruction: Elevated blood pressure, xantho-mas, and retinal exudates point to the presence of what?

Output: IHD riskfactors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Elevated blood pressure, xantho-mas, and retinal exudates point to the presence of what?. ### Response: IHD riskfactors.


Instruction: Pain reproduced by pressure on the chest walls suggests a musculoskeletal etiology but does not eliminate what possibility?

Output: angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pain reproduced by pressure on the chest walls suggests a musculoskeletal etiology but does not eliminate what possibility?. ### Response: angina.


Instruction: What does the chest walls suggest?

Output: musculoskeletal etiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the chest walls suggest?. ### Response: musculoskeletal etiology.


Instruction: What does not eliminate the possibility of angina due to IHD?

Output: Pain reproduced by pressure on the chest walls

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not eliminate the possibility of angina due to IHD?. ### Response: Pain reproduced by pressure on the chest walls.


Instruction: A resting ECG is recommended in patients without what cause of chest pain?

Output: noncardiac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A resting ECG is recommended in patients without what cause of chest pain?. ### Response: noncardiac.


Instruction: What type of SIHD have a worse prognosis than those with normalECGs57-59?

Output: Patients with SIHD who have the following abnormalities ona resting ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of SIHD have a worse prognosis than those with normalECGs57-59?. ### Response: Patients with SIHD who have the following abnormalities ona resting ECG.


Instruction: Evidence of prior MI, especially Q waves inmultiple leads or an R wave in V1 indicating a posteriorinfarction60, persistent ST-T-wave inversions, particularly inleads V1 to V361 to what?

Output: –64

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence of prior MI, especially Q waves inmultiple leads or an R wave in V1 indicating a posteriorinfarction60, persistent ST-T-wave inversions, particularly inleads V1 to V361 to what?. ### Response: –64.


Instruction: What is another name for left bundle-branch block?

Output: LBBB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for left bundle-branch block?. ### Response: LBBB.


Instruction: What is the second- or third-degree atrioventricular?

Output: left bundle-branch block (LBBB),bifascicular block

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the second- or third-degree atrioventricular?. ### Response: left bundle-branch block (LBBB),bifascicular block.


Instruction: What is CABG?

Output: coronary artery bypassgraft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CABG?. ### Response: coronary artery bypassgraft.


Instruction: What is PCI?

Output: percutaneous coronaryintervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PCI?. ### Response: percutaneous coronaryintervention.


Instruction: What is atypical angina(probable)?

Output: Meets 2 of the above characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atypical angina(probable)?. ### Response: Meets 2 of the above characteristics.


Instruction: What is noncardiacchest pain?

Output: Meets 1 or none of the typical anginal characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is noncardiacchest pain?. ### Response: Meets 1 or none of the typical anginal characteristics.


Instruction: When was the full text of Stable Ischemic Heart Disease published?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the full text of Stable Ischemic Heart Disease published?. ### Response: May 1, 2023.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett et al.


Instruction: What is the DOI: 10.1161/CIR.0000000000000678 September 10, 2019?

Output: Arnett et al 2019 ACC/AHA Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI: 10.1161/CIR.0000000000000678 September 10, 2019?. ### Response: Arnett et al 2019 ACC/AHA Guideline.


Instruction: What is the foundation of primary prevention?

Output: Assessment of ASCVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the foundation of primary prevention?. ### Response: Assessment of ASCVD risk.


Instruction: What should all individuals be encouraged to follow?

Output: a heart-healthy lifestyle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all individuals be encouraged to follow?. ### Response: a heart-healthy lifestyle.


Instruction: How much absolute ASCVD risk can be estimated?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much absolute ASCVD risk can be estimated?. ### Response: 10-year.


Instruction: What is used to guide decision-making for many preventive interventions?

Output: 10-year ASCVD risk estimate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to guide decision-making for many preventive interventions?. ### Response: 10-year ASCVD risk estimate.


Instruction: What is the 10-year absolute ASCVD risk?

Output: <7.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 10-year absolute ASCVD risk?. ### Response: <7.5%.


Instruction: What should be the start of a conversation with the pa-tient about?

Output: S2.2-37

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the start of a conversation with the pa-tient about?. ### Response: S2.2-37.


Instruction: What should not be the sole decision factor for the initiation of pharmacotherapy?

Output: risk-reducing strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be the sole decision factor for the initiation of pharmacotherapy?. ### Response: risk-reducing strategies.


Instruction: All risk estimation tools have what?

Output: inherent limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: All risk estimation tools have what?. ### Response: inherent limitations.


Instruction: Population-based risk scores must be interpreted in what way?

Output: in light of specific circumstances for individual patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Population-based risk scores must be interpreted in what way?. ### Response: in light of specific circumstances for individual patients.


Instruction: What must be interpreted in light of specific circumstances for individual patients?

Output: pop-ulation-based risk scores

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be interpreted in light of specific circumstances for individual patients?. ### Response: pop-ulation-based risk scores.


Instruction: What has been shown to overestimate ASCVD risk for cer -tain subgroups?

Output: PCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to overestimate ASCVD risk for cer -tain subgroups?. ### Response: PCE.


Instruction: What is reasonable to use to guide decisions about preventive interventions for bor-derline- or intermediate-risk adults?

Output: additional risk-enhancing factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to use to guide decisions about preventive interventions for bor-derline- or intermediate-risk adults?. ### Response: additional risk-enhancing factors.


Instruction: What may remain uncertain for many individuals with borderline or intermediate es-timated 10-year risk?

Output: the value of preventive therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may remain uncertain for many individuals with borderline or intermediate es-timated 10-year risk?. ### Response: the value of preventive therapy.


Instruction: What may be reluctant to take medical therapy without clearer evidence of increased ASCVD risk?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reluctant to take medical therapy without clearer evidence of increased ASCVD risk?. ### Response: patients.


Instruction: What is a reasonable tool to reclassify risk either upward or downward as part of shared decision-making?

Output: as-sessment of coronary artery calcium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable tool to reclassify risk either upward or downward as part of shared decision-making?. ### Response: as-sessment of coronary artery calcium.


Instruction: For younger adults 20 to 59 years of age, estimation of coronary artery calcium is what?

Output: lifetime risk may be considered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For younger adults 20 to 59 years of age, estimation of coronary artery calcium is what?. ### Response: lifetime risk may be considered.


Instruction: What age group may be considered for estimation of lifetime risk?

Output: younger adults 20 to 59 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What age group may be considered for estimation of lifetime risk?. ### Response: younger adults 20 to 59 years of age.


Instruction: For adults >75 years of age, what should the clinician and patient engage in a discussion about?

Output: the possible benefits of preventive therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For adults >75 years of age, what should the clinician and patient engage in a discussion about?. ### Response: the possible benefits of preventive therapies.


Instruction: What is a race- and sex-specific PCE?

Output: ASCVD Risk Estimator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a race- and sex-specific PCE?. ### Response: ASCVD Risk Estimator.


Instruction: What is the ASCVD Risk Estimator for asymptomatic adults?

Output: 10-year ASCVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ASCVD Risk Estimator for asymptomatic adults?. ### Response: 10-year ASCVD risk.


Instruction: What is the 10-year ASCVD risk for asymptomatic adults 40 to 75 years of age?

Output: <7.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 10-year ASCVD risk for asymptomatic adults 40 to 75 years of age?. ### Response: <7.5%.


Instruction: For management of stage 1 hypertension, adults should be classified as 10% or what?

Output: >10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For management of stage 1 hypertension, adults should be classified as 10% or what?. ### Response: >10%.


Instruction: What is STEMI?

Output: ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is STEMI?. ### Response: ST-elevation myocardial infarction.


Instruction: What is ST-elevation myocardial infarction?

Output: STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ST-elevation myocardial infarction?. ### Response: STEMI.


Instruction: When was Appendix A downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Appendix A downloaded?. ### Response: April 28, 2023.


Instruction: What is the name of the guideline for the secondary prevention of ischemic stroke?

Output: 2021 Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for the secondary prevention of ischemic stroke?. ### Response: 2021 Guideline.


Instruction: What are the recommendations for atrial fibrillation summarized in?

Output: online Data Supplement 32.COR LOE Recommendations1 A1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for atrial fibrillation summarized in?. ### Response: online Data Supplement 32.COR LOE Recommendations1 A1.


Instruction: What is recommended to reduce the risk of recurrent stroke in patients with nonvalvular AF and stroke or TIA?

Output: oral anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to reduce the risk of recurrent stroke in patients with nonvalvular AF and stroke or TIA?. ### Response: oral anticoagulation.


Instruction: What is oral anticoagulation indicated to reduce?

Output: the risk of recurrent stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is oral anticoagulation indicated to reduce?. ### Response: the risk of recurrent stroke.


Instruction: What is TIA?

Output: atrial flutter and stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TIA?. ### Response: atrial flutter and stroke.


Instruction: What is oral anticoagulation indicated to reduce the risk of recurrent stroke?

Output: In patients with nonvalvular AF and stroke or TIA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is oral anticoagulation indicated to reduce the risk of recurrent stroke?. ### Response: In patients with nonvalvular AF and stroke or TIA.


Instruction: What is apixaban, dabi-gatran, edoxaban or rivaroxaban recom-mended in preference to warfarin to reduce the risk of recurrent stroke?

Output: oral anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is apixaban, dabi-gatran, edoxaban or rivaroxaban recom-mended in preference to warfarin to reduce the risk of recurrent stroke?. ### Response: oral anticoagulation.


Instruction: What is indicated in patients with atrial flutter and stroke or TIA?

Output: anticoagulant therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated in patients with atrial flutter and stroke or TIA?. ### Response: anticoagulant therapy.


Instruction: What is indicated to reduce the risk of recurrent stroke?

Output: oral anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated to reduce the risk of recurrent stroke?. ### Response: oral anticoagulation.


Instruction: What does warfa-rin do in patients with AF and stroke or TIA?

Output: reduce the risk of recurrent stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does warfa-rin do in patients with AF and stroke or TIA?. ### Response: reduce the risk of recurrent stroke.


Instruction: What is the therapeutic INR level with warfa-rin?

Output: unable to maintain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the therapeutic INR level with warfa-rin?. ### Response: unable to maintain.


Instruction: What is recommended to reduce the risk of recurrent stroke?

Output: oral anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to reduce the risk of recurrent stroke?. ### Response: oral anticoagulation.


Instruction: How long is it reasonable to delay initiation of oral antico-agulation in patients with stroke at high risk of hemor-rhagic conversion?

Output: 14 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it reasonable to delay initiation of oral antico-agulation in patients with stroke at high risk of hemor-rhagic conversion?. ### Response: 14 days.


Instruction: Why is it reasonable to delay initiation of oral antico-agulation beyond 14 days?

Output: to reduce the risk of ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is it reasonable to delay initiation of oral antico-agulation beyond 14 days?. ### Response: to reduce the risk of ICH.


Instruction: In patients with TIA in the setting of nonvalvu-lar AF, it is reasonable to initiate anticoagu-lation immediately after the index event to reduce the risk of recurrent stroke?

Output: oral anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with TIA in the setting of nonvalvu-lar AF, it is reasonable to initiate anticoagu-lation immediately after the index event to reduce the risk of recurrent stroke?. ### Response: oral anticoagulation.


Instruction: To reduce the risk of recurrent stroke.

Output: oral anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To reduce the risk of recurrent stroke.. ### Response: oral anticoagulation.


Instruction: What is the watchman used for in patients with stroke or TIA in the setting of nonvalvular AF?

Output: percutaneous closure of the left atrial appendage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the watchman used for in patients with stroke or TIA in the setting of nonvalvular AF?. ### Response: percutaneous closure of the left atrial appendage.


Instruction: How long can a patient tolerate anticoagulation?

Output: 45 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long can a patient tolerate anticoagulation?. ### Response: 45 days.


Instruction: What device is used to reduce the chance of recurrent stroke and bleeding?

Output: Watchman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What device is used to reduce the chance of recurrent stroke and bleeding?. ### Response: Watchman.


Instruction: What is the watchman device used for?

Output: percutaneous closure of the left atrial appendage with the Watchman device to reduce the chance of recurrent stroke and bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the watchman device used for?. ### Response: percutaneous closure of the left atrial appendage with the Watchman device to reduce the chance of recurrent stroke and bleeding.


Instruction: How many days after the stroke should anticoagulation be initiated?

Output: 2 to 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days after the stroke should anticoagulation be initiated?. ### Response: 2 to 14.


Instruction: How long after index event is it reasonable to initiate anticoagulation?

Output: 2 to 14 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after index event is it reasonable to initiate anticoagulation?. ### Response: 2 to 14 days.


Instruction: What is the dose adjusted if a patient has end-stage renal disease or dialysis?

Output: apixaban (dose adjusted if indicated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the dose adjusted if a patient has end-stage renal disease or dialysis?. ### Response: apixaban (dose adjusted if indicated.


Instruction: What is an important cause of cardioembolic stroke?

Output: AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important cause of cardioembolic stroke?. ### Response: AF.


Instruction: What is the initial clinical presentation of SynopsisAF?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the initial clinical presentation of SynopsisAF?. ### Response: stroke.


Instruction: What is NICE 2018 Subject to?

Output: Notice of rights

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018 Subject to?. ### Response: Notice of rights.


Instruction: What is the ISBN number for the reference list?

Output: 9 78-1-4731 -3093 -7 10 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ISBN number for the reference list?. ### Response: 9 78-1-4731 -3093 -7 10 11.


Instruction: What is a Glossary?

Output: Acronyms and abbreviations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Glossary?. ### Response: Acronyms and abbreviations.


Instruction: What are Guideline-specific terms?

Output: 512 13.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Guideline-specific terms?. ### Response: 512 13.1.


Instruction: How often do umbilical ar tery doppler v elocimetr y every 2 weeks?

Output: at least 2  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often do umbilical ar tery doppler v elocimetr y every 2 weeks?. ### Response: at least 2  weeks.


Instruction: What are women wit h pre-eclampsia or se vere gestational h yper tension?

Output: hyper tensiv e disor ders of Hyper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are women wit h pre-eclampsia or se vere gestational h yper tension?. ### Response: hyper tensiv e disor ders of Hyper tension.


Instruction: What is a gestational hyper tension?

Output: disor ders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a gestational hyper tension?. ### Response: disor ders.


Instruction: What is the timing and natur e of futur e fetal monitoring?

Output: 28 and 30  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the timing and natur e of futur e fetal monitoring?. ### Response: 28 and 30  weeks.


Instruction: When should ant enatal cor ticost eroids be given?

Output: if and when

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should ant enatal cor ticost eroids be given?. ### Response: if and when.


Instruction: Who should plan f or discussion wit h neonatal paediatricians and obst etric anaesthetists?

Output: women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should plan f or discussion wit h neonatal paediatricians and obst etric anaesthetists?. ### Response: women.


Instruction: What should women w ho ne ed addi tional f etal moni toring?

Output: if clinically indicat ed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should women w ho ne ed addi tional f etal moni toring?. ### Response: if clinically indicat ed.


Instruction: Do you carry out an ultrasound f or fetal gr owth and amniotic fluid v olume assessment and umbilical ar tery doppler velocimetr y starting at betw een 28 and 30 weeks?

Output: Women w ho ne ed addi tional f etal moni toring 1.6.11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do you carry out an ultrasound f or fetal gr owth and amniotic fluid v olume assessment and umbilical ar tery doppler velocimetr y starting at betw een 28 and 30 weeks?. ### Response: Women w ho ne ed addi tional f etal moni toring 1.6.11.


Instruction: Do you need at least 2 weeks bef ore previous gestational age of onset?

Output: at least 2  weeks bef ore previous gestational age of onset if earlier t han 28  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do you need at least 2 weeks bef ore previous gestational age of onset?. ### Response: at least 2  weeks bef ore previous gestational age of onset if earlier t han 28  weeks.


Instruction: Bef ore previous gestational age of onset if earlier t han 28 weeks) and r epeating 4 weeks lat er in w omen with previous?

Output: severe pre-eclampsia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bef ore previous gestational age of onset if earlier t han 28 weeks) and r epeating 4 weeks lat er in w omen with previous?. ### Response: severe pre-eclampsia.


Instruction: • severe pre-eclampsia • pre-Eclampses that r resulted in bir th before 34 weeks?

Output: placental abruption

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: • severe pre-eclampsia • pre-Eclampses that r resulted in bir th before 34 weeks?. ### Response: placental abruption.


Instruction: How long was pre-eclampsia for a baby whose bir th weight was less than the 10th centile?

Output: 34  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was pre-eclampsia for a baby whose bir th weight was less than the 10th centile?. ### Response: 34  weeks.


Instruction: What is intraut erine deat h?

Output: placental abruption

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is intraut erine deat h?. ### Response: placental abruption.


Instruction: Where is placental abruption?

Output: intraut erine deat h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is placental abruption?. ### Response: intraut erine deat h.


Instruction: In women who need additional f etal monit oring, what should be done?

Output: carr y out car diotocograph y only if clinically indicat ed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In women who need additional f etal monit oring, what should be done?. ### Response: carr y out car diotocograph y only if clinically indicat ed.


Instruction: What is the r ecommendation for etal monitoring?

Output: 1.6.11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the r ecommendation for etal monitoring?. ### Response: 1.6.11.


Instruction: Carr y out car diotocograph y only if what is clinically indicat ed?

Output: women who need additional f etal monit oring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Carr y out car diotocograph y only if what is clinically indicat ed?. ### Response: women who need additional f etal monit oring.


Instruction: Intrapar tum c are 1.7.1 What is hyper tension in pregnancy?

Output: disor ders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Intrapar tum c are 1.7.1 What is hyper tension in pregnancy?. ### Response: disor ders.


Instruction: What is NG133?

Output: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NG133?. ### Response: diagnosis and management.


Instruction: What is NICE 2023?

Output: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2023?. ### Response: diagnosis and management.


Instruction: When was the last updat ed?

Output: 17 April 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed?. ### Response: 17 April 2023.


Instruction: What is an independent risk factor for mortality inpatients undergoing cardiac surgery?

Output: Hyperglycemia duringcardiopulmonary bypass

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an independent risk factor for mortality inpatients undergoing cardiac surgery?. ### Response: Hyperglycemia duringcardiopulmonary bypass.


Instruction: What is associated with a worsening hospital outcome aftercardiac surgery in diabetic patients?

Output: Poor intraoperative bloodglucose control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with a worsening hospital outcome aftercardiac surgery in diabetic patients?. ### Response: Poor intraoperative bloodglucose control.


Instruction: What does continuous intravenousinsulin infusion reduce the incidence of?

Output: deep sternal wound infection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does continuous intravenousinsulin infusion reduce the incidence of?. ### Response: deep sternal wound infection.


Instruction: What reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures?

Output: Continuous intravenousinsulin infusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures?. ### Response: Continuous intravenousinsulin infusion.


Instruction: What does continuous intravenous insulin infusion reduce?

Output: the incidence of deep sternal wound infection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does continuous intravenous insulin infusion reduce?. ### Response: the incidence of deep sternal wound infection.


Instruction: When was the Ann Thorac Surg.67:352-60.594?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Thorac Surg.67:352-60.594?. ### Response: 1999.


Instruction: What is the name of the Society of ThoracicSurgeons practice guideline series?

Output: Blood glucose management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Society of ThoracicSurgeons practice guideline series?. ### Response: Blood glucose management.


Instruction: What is a possible cause of increased mortality after CABG surgery?

Output: impaired fasting bloodglucose levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible cause of increased mortality after CABG surgery?. ### Response: impaired fasting bloodglucose levels.


Instruction: What is the name of the practice guideline series for blood glucose management during cardiac surgery?

Output: The Society of ThoracicSurgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the practice guideline series for blood glucose management during cardiac surgery?. ### Response: The Society of ThoracicSurgeons.


Instruction: When was the Ann Thorac Surg. 2009 published?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Thorac Surg. 2009 published?. ### Response: 1999.


Instruction: What is hypothy-roidism and the risk of?

Output: coronary heart disease and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hypothy-roidism and the risk of?. ### Response: coronary heart disease and mortality.


Instruction: What is the risk of transient atrial fibrillation after coronaryartery bypass grafting?

Output: increase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of transient atrial fibrillation after coronaryartery bypass grafting?. ### Response: increase.


Instruction: What does triiodothyronine therapy lower?

Output: incidence of atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does triiodothyronine therapy lower?. ### Response: incidence of atrial fibrillation.


Instruction: What is the incidence of atrial fibrillation after cardiac operations?

Output: Triiodothyronine therapylowers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence of atrial fibrillation after cardiac operations?. ### Response: Triiodothyronine therapylowers.


Instruction: Who is the Duke T3 StudyGroup?

Output: Bennett-Guerrero E, Jimenez JL, White WD, et al., Duke T3 StudyGroup. Cardiovascular effects of intravenous triiodothyronine inpatients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Duke T3 StudyGroup?. ### Response: Bennett-Guerrero E, Jimenez JL, White WD, et al., Duke T3 StudyGroup. Cardiovascular effects of intravenous triiodothyronine inpatients.


Instruction: In what year did JAMA publish 275:687-92.602?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did JAMA publish 275:687-92.602?. ### Response: 1996.


Instruction: What is the name of the double-blind, placebo-controlled trial?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the double-blind, placebo-controlled trial?. ### Response: JAMA.


Instruction: When was the JAMA 275:687–92.602?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA 275:687–92.602?. ### Response: 1996.


Instruction: What is treated after coronary-artery bypass surgery?

Output: Thyroid hormone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is treated after coronary-artery bypass surgery?. ### Response: Thyroid hormone.


Instruction: What type of grafting is used?

Output: coronary artery bypass

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of grafting is used?. ### Response: coronary artery bypass.


Instruction: What is the name of the randomized, double-blind, placebo-controlled trial of metoprolol?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, double-blind, placebo-controlled trial of metoprolol?. ### Response: JAMA.


Instruction: What is a prophylactic metoprolol used for?

Output: reduction ofhospital length of stay after heart surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prophylactic metoprolol used for?. ### Response: reduction ofhospital length of stay after heart surgery.


Instruction: What is the beta-Blocker Length Of Stay?

Output: reduction ofhospital length of stay after heart surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the beta-Blocker Length Of Stay?. ### Response: reduction ofhospital length of stay after heart surgery.


Instruction: What is the name of the Phase 3 AF Trials of NOAC vs Warfarin: Summary of Key Efficacy and Safety Results?

Output: TrialRE-LY72ROCKET-AF73ARISTOTLE74ENGAGE AF-TIMI 4876

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Phase 3 AF Trials of NOAC vs Warfarin: Summary of Key Efficacy and Safety Results?. ### Response: TrialRE-LY72ROCKET-AF73ARISTOTLE74ENGAGE AF-TIMI 4876.


Instruction: What was the outcome of Phase 3 of the AF trials?

Output: TrialRE-LY72ROCKET-AF73ARISTOTLE74ENGAGE AF-TIMI 4876

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of Phase 3 of the AF trials?. ### Response: TrialRE-LY72ROCKET-AF73ARISTOTLE74ENGAGE AF-TIMI 4876.


Instruction: What is NA 0.88 (0.75-1.03) NA 0.79 (0.0.65-0.95) NA 0.87 (0.73-1.04) 1.13 (0.96-1.34) NAP.004.29 NA NA.01 NA NAIschemic strokeEvent rate(%/y)0.92 1.34 1.22 1.34 142 0.97 1.05 1.77 1.25 HR (95% CI) 0.76 (0.59-0.97) 1.11 (0.88-1.39) NA 0.94 (0.74-1.1

Output: 0.58-0.90) 0.90

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NA 0.88 (0.75-1.03) NA 0.79 (0.0.65-0.95) NA 0.87 (0.73-1.04) 1.13 (0.96-1.34) NAP.004.29 NA NA.01 NA NAIschemic strokeEvent rate(%/y)0.92 1.34 1.22 1.34 142 0.97 1.05 1.77 1.25 HR (95% CI) 0.76 (0.59-0.97) 1.11 (0.88-1.39) NA 0.94 (0.74-1.1. ### Response: 0.58-0.90) 0.90.


Instruction: What is NA 0.94 (0.75-1.17) NA 0.92 (0.74-1.13) NA 1.00 (0.83-1.19) NA 1.41 (1.19-1.67) NAP.03.35 NA.58 NA.42 NA.97.001 NAHemorrhagicstrokeEvent rate(%/y)0.10 0,12 0,38 0,26 0,44 0,24 0,47 0,26 0.16 0.47 HR (95% CI) 0.26 (0.17-0.56) NA 0.59 (0.37-0.77)

Output: 1.25HR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NA 0.94 (0.75-1.17) NA 0.92 (0.74-1.13) NA 1.00 (0.83-1.19) NA 1.41 (1.19-1.67) NAP.03.35 NA.58 NA.42 NA.97.001 NAHemorrhagicstrokeEvent rate(%/y)0.10 0,12 0,38 0,26 0,44 0,24 0,47 0,26 0.16 0.47 HR (95% CI) 0.26 (0.17-0.56) NA 0.59 (0.37-0.77). ### Response: 1.25HR.


Instruction: What is the NAMIEvent rate(%/y)0.81 0.82 0.64 0.91 1.12 0.53 0.61 0.70 0.89 0.75HR (95% CI) 1.27 (0.94-1.71) 1.29 (0.96-1.75) NA 0.81 (0.63-1.06) NA 0.88 (0.66-1.17) NA 0.94 (0.74-1.19) NA 0.19 (0.95-1.49)

Output: 0.96-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NAMIEvent rate(%/y)0.81 0.82 0.64 0.91 1.12 0.53 0.61 0.70 0.89 0.75HR (95% CI) 1.27 (0.94-1.71) 1.29 (0.96-1.75) NA 0.81 (0.63-1.06) NA 0.88 (0.66-1.17) NA 0.94 (0.74-1.19) NA 0.19 (0.95-1.49). ### Response: 0.96-1.


Instruction: NA 0.88 (0.66-1.17) NA 0.94 (0.74-1.19) 1.19 (0.95-1.49) NAP.12.09 NA.12 NA.37 NA.60.13 NAAll-cause deathEvent rate(%/y)3.64 3.75 4.13 1.87 2.21 3.52 3.94 3.99 3.80 4.35HR (95% CI) 0.87 (0.79-0.96) NA 0.92 (0.83-1.01) NA 0.89 (0.80-1.0) NA 0.85 (0.70-1.02)

Output: NA 0.81 (0.63-1.06) NA 0.88 (0.66-1.17) NA 0.94 (0.74-1.19) 1.19 (0.95-1.49) NAP .12 .09 NA .12 NA .37 NA .60 .13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: NA 0.88 (0.66-1.17) NA 0.94 (0.74-1.19) 1.19 (0.95-1.49) NAP.12.09 NA.12 NA.37 NA.60.13 NAAll-cause deathEvent rate(%/y)3.64 3.75 4.13 1.87 2.21 3.52 3.94 3.99 3.80 4.35HR (95% CI) 0.87 (0.79-0.96) NA 0.92 (0.83-1.01) NA 0.89 (0.80-1.0) NA 0.85 (0.70-1.02). ### Response: NA 0.81 (0.63-1.06) NA 0.88 (0.66-1.17) NA 0.94 (0.74-1.19) 1.19 (0.95-1.49) NAP .12 .09 NA .12 NA .37 NA .60 .13.


Instruction: What is the NAP.05.13 NA.07 NA.047 NA.08.006 NASafetyMajor bleedingEvent rate(%/y)3.32 2.87 3.573.6 2.13 3.09 2.75 1.61 3.43HR (95% CI) 0.93 (0.81-1.07) 0.80 (0.70-0.93) NA 1.04 (0.90-1.20) NA 0.69 (0.60-0.80)NA 0.47 (0.41-0.55)

Output: <.001 NA <.001 <.001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NAP.05.13 NA.07 NA.047 NA.08.006 NASafetyMajor bleedingEvent rate(%/y)3.32 2.87 3.573.6 2.13 3.09 2.75 1.61 3.43HR (95% CI) 0.93 (0.81-1.07) 0.80 (0.70-0.93) NA 1.04 (0.90-1.20) NA 0.69 (0.60-0.80)NA 0.47 (0.41-0.55). ### Response: <.001 NA <.001 <.001.


Instruction: What is the NAICHEvent rate(%/y)0.32 0.23 0.760.50.7 0.33 0.80 0.39 0.26 0.85(Continued)1152 Evidence-Based Medicine?

Output: NA <.001 <.001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NAICHEvent rate(%/y)0.32 0.23 0.760.50.7 0.33 0.80 0.39 0.26 0.85(Continued)1152 Evidence-Based Medicine?. ### Response: NA <.001 <.001.


Instruction: What is the age dependence of complete heart block complicating radiofrequency ablation of the atrioventricular nodal slow pathway?

Output: Age dependence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age dependence of complete heart block complicating radiofrequency ablation of the atrioventricular nodal slow pathway?. ### Response: Age dependence.


Instruction: What is Goldberg AS, Bathina MN, Mickelsen S, et al.?

Output: Long-term outcomes on quality-of-life and health care costs in patients with supraventricular tachycardia (radiofrequency catheter ablation versus medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Goldberg AS, Bathina MN, Mickelsen S, et al.?. ### Response: Long-term outcomes on quality-of-life and health care costs in patients with supraventricular tachycardia (radiofrequency catheter ablation versus medical therapy.


Instruction: What is the difference between radiofrequency catheter ablation and medical therapy?

Output: quality of life and healthcare costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between radiofrequency catheter ablation and medical therapy?. ### Response: quality of life and healthcare costs.


Instruction: What are the two main aspects of supraventricular tachycardia?

Output: radiofrequency catheter ablation versus medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two main aspects of supraventricular tachycardia?. ### Response: radiofrequency catheter ablation versus medical therapy.


Instruction: When was the last issue of Am J Cardiol published?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of Am J Cardiol published?. ### Response: 1999.


Instruction: What is the impact of tachycardia on quality of life and healthcare costs?

Output: Long-term outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of tachycardia on quality of life and healthcare costs?. ### Response: Long-term outcomes.


Instruction: When was the Am J Cardiol 82:589–93?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol 82:589–93?. ### Response: 1998.


Instruction: How long did it take for patients to maintain high quality of lives after ablation?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for patients to maintain high quality of lives after ablation?. ### Response: 5-year.


Instruction: What was the result of a large retrospective patient cohort?

Output: Sustained high quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of a large retrospective patient cohort?. ### Response: Sustained high quality of life.


Instruction: What is ventricular tachycardia?

Output: radiofrequency catheter ablation versus medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ventricular tachycardia?. ### Response: radiofrequency catheter ablation versus medical therapy.


Instruction: What is the name of the large retrospective patient cohort?

Output: Patients’ Perspective on Radiofrequency Catheter Ablation of A VRT and A VNRT Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the large retrospective patient cohort?. ### Response: Patients’ Perspective on Radiofrequency Catheter Ablation of A VRT and A VNRT Study.


Instruction: When was the int J Med Sci.6:28–36?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the int J Med Sci.6:28–36?. ### Response: 2009.


Instruction: How did patients perceive symptoms and quality of life after ablation?

Output: Healthcare utilization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did patients perceive symptoms and quality of life after ablation?. ### Response: Healthcare utilization.


Instruction: What is the effect of radiofrequency ablation treatment on quality of life and anxiety in patients with supraven-tricular tachycardia?

Output: Gender-related differ -ences in outcomes and resource utilization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of radiofrequency ablation treatment on quality of life and anxiety in patients with supraven-tricular tachycardia?. ### Response: Gender-related differ -ences in outcomes and resource utilization.


Instruction: What are the results of gender-related differ-ences in outcomes and resource utilization?

Output: Patients’ Perspective on Radiofrequency Catheter Ablation of A VRT and A VNRT Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of gender-related differ-ences in outcomes and resource utilization?. ### Response: Patients’ Perspective on Radiofrequency Catheter Ablation of A VRT and A VNRT Study.


Instruction: What are gender-related differences in outcomes and resource utilization in patients undergoing radio-frequency ablation of supraventricular tachycardia?

Output: differ -ences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are gender-related differences in outcomes and resource utilization in patients undergoing radio-frequency ablation of supraventricular tachycardia?. ### Response: differ -ences.


Instruction: What are the results from Patients’ Perspective on Radiofrequency Catheter Ablation of A VRT and A VNRT Study?

Output: Gender-related differ -ences in outcomes and resource utilization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results from Patients’ Perspective on Radiofrequency Catheter Ablation of A VRT and A VNRT Study?. ### Response: Gender-related differ -ences in outcomes and resource utilization.


Instruction: What is the name of the patient with drug refractory atrioven-tricular nodal reentrant tachycardia treated with radiofrequency catheter ablation?

Output: Larson MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the patient with drug refractory atrioven-tricular nodal reentrant tachycardia treated with radiofrequency catheter ablation?. ### Response: Larson MS.


Instruction: When was the Am J Cardiol. 84:471–3, A9. 547?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol. 84:471–3, A9. 547?. ### Response: 1999.


Instruction: What is one of the key words of this study?

Output: AHA Scientific Statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the key words of this study?. ### Response: AHA Scientific Statements.


Instruction: After catheter ablation of atrial flutter?

Output: Healthcare utilization and clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After catheter ablation of atrial flutter?. ### Response: Healthcare utilization and clinical outcomes.


Instruction: What is tachycardia, supraventricular and atrioventricular nodal reentry?

Output: Wolff-Parkinson-White syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tachycardia, supraventricular and atrioventricular nodal reentry?. ### Response: Wolff-Parkinson-White syndrome.


Instruction: Wolff-Parkinson-White syndrome is associated with what?

Output: catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Wolff-Parkinson-White syndrome is associated with what?. ### Response: catheter ablation.


Instruction: What are anti-arrhythmia agents?

Output: ◼ accessory atrioventricular bundle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are anti-arrhythmia agents?. ### Response: ◼ accessory atrioventricular bundle.


Instruction: What are heart defects, congenital  death, sudden  electrophysiologic techniques, cardiac  sinus tachycardia?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are heart defects, congenital  death, sudden  electrophysiologic techniques, cardiac  sinus tachycardia?. ### Response: ◼.


Instruction: What is the difference between cestac and enoxaparin in obese patients and patients with severe renal impairment?

Output: pharmacodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between cestac and enoxaparin in obese patients and patients with severe renal impairment?. ### Response: pharmacodynamics.


Instruction: What are the results of the ESSENCE and TIMI 11B studies?

Output: enoxaparin in patients who are obese and patients with severe renal impairment: analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the ESSENCE and TIMI 11B studies?. ### Response: enoxaparin in patients who are obese and patients with severe renal impairment: analysis.


Instruction: What did Cestac P, Bagheri H, Lapeyre-Mestre M, et al. find out about the use and safety of low molecular weight heparins in medical inpatients?

Output: Utilisation and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Cestac P, Bagheri H, Lapeyre-Mestre M, et al. find out about the use and safety of low molecular weight heparins in medical inpatients?. ### Response: Utilisation and safety.


Instruction: What is the name of the study conducted in medical inpatients?

Output: Drug Saf

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study conducted in medical inpatients?. ### Response: Drug Saf.


Instruction: How many patients were studied in 2003?

Output: 197 - 207

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were studied in 2003?. ### Response: 197 - 207.


Instruction: What is enoxaparin and bleeding complications?

Output: a review in patients with and without renal insufﬁ  ciency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin and bleeding complications?. ### Response: a review in patients with and without renal insufﬁ  ciency.


Instruction: What was a review in patients with and without renal insuffi ciency?

Output: Enoxaparin and bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a review in patients with and without renal insuffi ciency?. ### Response: Enoxaparin and bleeding complications.


Instruction: How many ( 7 ) were there in 2000?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 7 ) were there in 2000?. ### Response: 20.


Instruction: What is the pharmacokinetics of a drug?

Output: comparative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pharmacokinetics of a drug?. ### Response: comparative.


Instruction: What is Jariwala's name?

Output: N

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Jariwala's name?. ### Response: N.


Instruction: What is enoxaparin used for in obese volunteers?

Output: pharma-cokinetics and pharmacodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin used for in obese volunteers?. ### Response: pharma-cokinetics and pharmacodynamics.


Instruction: How many ( 3 ): 308-318 in 2002?

Output: 72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 3 ): 308-318 in 2002?. ### Response: 72.


Instruction: Rabbat CG, Cook CG, What is the name of the drug used in obese patients?

Output: enoxaparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Rabbat CG, Cook CG, What is the name of the drug used in obese patients?. ### Response: enoxaparin.


Instruction: What is Dalteparin thromboprophylaxis for critically ill medical-surgical patients with renal insufficiency?

Output: low-molecular-weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Dalteparin thromboprophylaxis for critically ill medical-surgical patients with renal insufficiency?. ### Response: low-molecular-weight heparin.


Instruction: What is the name of the group that studies critical care?

Output: Canadian Critical Care Trials Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies critical care?. ### Response: Canadian Critical Care Trials Group.


Instruction: How many cases were there in 2005?

Output: 357 - 363

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases were there in 2005?. ### Response: 357 - 363.


Instruction: What was the number of cases?

Output: 167

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the number of cases?. ### Response: 167.


Instruction: What is dalteparin used for in critically ill patients?

Output: Prophylaxis against deep vein thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is dalteparin used for in critically ill patients?. ### Response: Prophylaxis against deep vein thrombosis.


Instruction: What is the DIRECT study?

Output: Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufﬁ  ciency with the low-molecular-weight heparin dalteparin: an assessment of safety and pharmacodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DIRECT study?. ### Response: Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufﬁ  ciency with the low-molecular-weight heparin dalteparin: an assessment of safety and pharmacodynamics.


Instruction: How many years was Tinzaparin used?

Output: eight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years was Tinzaparin used?. ### Response: eight.


Instruction: What year did Tinzaperin first appear in the literature?

Output: 1987

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Tinzaperin first appear in the literature?. ### Response: 1987.


Instruction: Tinzaparin and enox-aparin given at prophylactic dose for eight days in medical elderly patients with impaired renal function: a comparative pharmacokinetic study?

Output: M ,  Drouet   L ,  et al .

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tinzaparin and enox-aparin given at prophylactic dose for eight days in medical elderly patients with impaired renal function: a comparative pharmacokinetic study?. ### Response: M ,  Drouet   L ,  et al ..


Instruction: How many pages were there in the 97 ( 4 ): 581 - 586?

Output: 168

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages were there in the 97 ( 4 ): 581 - 586?. ### Response: 168.


Instruction: What is the molecular weight of heparin?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the molecular weight of heparin?. ### Response: low.


Instruction: What are the effects on eicosanoids, clotting and complement factors?

Output: Protamine reversal of anticoagulation achieved with a low molecular weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects on eicosanoids, clotting and complement factors?. ### Response: Protamine reversal of anticoagulation achieved with a low molecular weight heparin.


Instruction: What is PK 10169?

Output: Partial rever-sal of low molecular weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PK 10169?. ### Response: Partial rever-sal of low molecular weight heparin.


Instruction: What is the name of the drug that has a low molecular weight?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that has a low molecular weight?. ### Response: heparin.


Instruction: What is the effect of protamine sulfate on Xa activation?

Output: Partial rever-sal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of protamine sulfate on Xa activation?. ### Response: Partial rever-sal.


Instruction: How many. 170. Racanelli A, Fareed J, Walenga JM, Coyne E. Biochemical and pharmacologic studies on the protamine interactions. 2012 American College of Chest.

Output: 170

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many. 170. Racanelli A, Fareed J, Walenga JM, Coyne E. Biochemical and pharmacologic studies on the protamine interactions. 2012 American College of Chest.. ### Response: 170.


Instruction: What year was the American College of Chest Physicians founded?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the American College of Chest Physicians founded?. ### Response: 2012.


Instruction: Who wrote the book The Protamine Interactions?

Output: Kimberly Henricks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the book The Protamine Interactions?. ### Response: Kimberly Henricks.


Instruction: On what date was the book released?

Output: February 10, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was the book released?. ### Response: February 10, 2012.


Instruction: What is one of the most frequent dis-orders that causes secondary hypertension?

Output: Primary aldosteronism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the most frequent dis-orders that causes secondary hypertension?. ### Response: Primary aldosteronism.


Instruction: What percentage of patients with hypertension have primary aldosteronism?

Output: 5% to 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with hypertension have primary aldosteronism?. ### Response: 5% to 10%.


Instruction: What causes secondary hypertension?

Output: Primary aldosteronism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes secondary hypertension?. ### Response: Primary aldosteronism.


Instruction: What causes greater target organ damage in primary aldosteronism than in primary hypertony?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes greater target organ damage in primary aldosteronism than in primary hypertony?. ### Response: hypertension.


Instruction: How much increase in HF do patients with primary aldenosterononism have in their blood pressure?

Output: 3.7-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increase in HF do patients with primary aldenosterononism have in their blood pressure?. ### Response: 3.7-fold.


Instruction: What is AF?

Output: atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AF?. ### Response: atrial fibrillation.


Instruction: What are LVH and diastolic dysfunc-tion?

Output: increased left ventricular hypertrophy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are LVH and diastolic dysfunc-tion?. ### Response: increased left ventricular hypertrophy.


Instruction: Why do patients with primary hypertension have more kidney damage?

Output: matched for BP level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do patients with primary hypertension have more kidney damage?. ### Response: matched for BP level.


Instruction: What is the primary hypertension matched for?

Output: BP level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary hypertension matched for?. ### Response: BP level.


Instruction: What are the deleterious effects of aldosterone overproduction often reversible with?

Output: unilateral laparoscopic adrenalectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the deleterious effects of aldosterone overproduction often reversible with?. ### Response: unilateral laparoscopic adrenalectomy.


Instruction: Who should be screening patients with hypertension at increased risk of?

Output: primary aldosteron-ism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should be screening patients with hypertension at increased risk of?. ### Response: primary aldosteron-ism.


Instruction: What is the term for an adrenal lesion discovered on a computed tomography or MRI scan?

Output: incidentaloma

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for an adrenal lesion discovered on a computed tomography or MRI scan?. ### Response: incidentaloma.


Instruction: What type of aldosteron-ism is beneficial?

Output: primary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of aldosteron-ism is beneficial?. ### Response: primary.


Instruction: Patients with hypertension and a history of early onset hypertension may have what?

Output: primary aldosteronism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with hypertension and a history of early onset hypertension may have what?. ### Response: primary aldosteronism.


Instruction: What may cause primary aldosteronism?

Output: glucocorticoid-remediable al-dosteronism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may cause primary aldosteronism?. ### Response: glucocorticoid-remediable al-dosteronism.


Instruction: What is the most accurate and reliable means of screening for primary Table 14?

Output: aldosterone:renin activity ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most accurate and reliable means of screening for primary Table 14?. ### Response: aldosterone:renin activity ratio.


Instruction: What is a common cause of elevated BP*?

Output: offee use in patients with hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of elevated BP*?. ### Response: offee use in patients with hypertension.


Instruction: How many drinks a day should you drink alcohol for women?

Output: ≤1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drinks a day should you drink alcohol for women?. ### Response: ≤1.


Instruction: What is another name for amphetamine?

Output: mphetamines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for amphetamine?. ### Response: mphetamines.


Instruction: What is another name for SSRIs?

Output: alternative agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for SSRIs?. ### Response: alternative agents.


Instruction: What type of antipsychotics are clozapine?

Output: Atypical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of antipsychotics are clozapine?. ### Response: Atypical.


Instruction: Where is behavior therapy recommended?

Output: ADHDS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is behavior therapy recommended?. ### Response: ADHDS.


Instruction: Aripiprazole and ziprasidone are examples of what type of agents?

Output: mineralocorticoid receptor antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aripiprazole and ziprasidone are examples of what type of agents?. ### Response: mineralocorticoid receptor antagonists.


Instruction: How much caffeine should a person consume in a day?

Output: <300 mg/d

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much caffeine should a person consume in a day?. ### Response: <300 mg/d.


Instruction: What type of hypertension is caffeine associated with?

Output: uncontrolled

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypertension is caffeine associated with?. ### Response: uncontrolled.


Instruction: How is caffeine used in patients with hypertension?

Output: acute increases in BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is caffeine used in patients with hypertension?. ### Response: acute increases in BP.


Instruction: How many primary outcome events were there in the benazepril/amlodipine group?

Output: 552

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many primary outcome events were there in the benazepril/amlodipine group?. ### Response: 552.


Instruction: What was the mean follow-up of the trial?

Output: 36 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean follow-up of the trial?. ### Response: 36 months.


Instruction: How long did it take for the trial to be terminated?

Output: 36 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for the trial to be terminated?. ### Response: 36 months.


Instruction: What was the absolute risk reduction of the benazepril/hydrochlorothiazide group?

Output: 2.2%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the absolute risk reduction of the benazepril/hydrochlorothiazide group?. ### Response: 2.2%.


Instruction: How many participants were in the ACCOMPLISH trial with diabetes mellitus?

Output: 73 913

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants were in the ACCOMPLISH trial with diabetes mellitus?. ### Response: 73 913.


Instruction: How many recent meta-analyses investigated the effect of BP lowering in patients with type 2 diabetes mellitus?

Output: Two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many recent meta-analyses investigated the effect of BP lowering in patients with type 2 diabetes mellitus?. ### Response: Two.


Instruction: How many patients were included in the first meta-analysis?

Output: 37 760

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were included in the first meta-analysis?. ### Response: 37 760.


Instruction: How long was the follow-up of intensive BP control?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the follow-up of intensive BP control?. ### Response: 1 year.


Instruction: What was associated with a 10% reduction in all-cause mortality and a 17% reduction in stroke?

Output: Intensive BP control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a 10% reduction in all-cause mortality and a 17% reduction in stroke?. ### Response: Intensive BP control.


Instruction: How much increase was there in serious adverse effects?

Output: 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increase was there in serious adverse effects?. ### Response: 20%.


Instruction: What percentage increase in serious adverse effects was there?

Output: 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage increase in serious adverse effects was there?. ### Response: 20%.


Instruction: What was the SBP of a stroke at 120 mm Hg?

Output: <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the SBP of a stroke at 120 mm Hg?. ### Response: <120 mm Hg.


Instruction: At what level was there a 40% increase in severe adverse events?

Output: <130 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what level was there a 40% increase in severe adverse events?. ### Response: <130 mm Hg.


Instruction: How many patients with diabetes mellitus were randomized in the second meta-analysis?

Output: 73 913

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with diabetes mellitus were randomized in the second meta-analysis?. ### Response: 73 913.


Instruction: How many patient-years of exposure were there in 31 intervention trials?

Output: 295 652

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patient-years of exposure were there in 31 intervention trials?. ### Response: 295 652.


Instruction: What did more aggressive treatment reduce stroke incidence by?

Output: 9%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did more aggressive treatment reduce stroke incidence by?. ### Response: 9%.


Instruction: How much did less aggressive BP control reduce the risk of stroke?

Output: 31%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did less aggressive BP control reduce the risk of stroke?. ### Response: 31%.


Instruction: What was the RR of BP?

Output: 0.61

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of BP?. ### Response: 0.61.


Instruction: In a meta-regression analy-sis, what was the risk for stroke reduced by?

Output: 13%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a meta-regression analy-sis, what was the risk for stroke reduced by?. ### Response: 13%.


Instruction: What percentage for each 2-mm Hg reduction in DBP?

Output: 11.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage for each 2-mm Hg reduction in DBP?. ### Response: 11.5%.


Instruction: What did the Medical Research Council/British Heart Foundation Heart Protection Study find in patients with diabetes mellitus?

Output: BP lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Medical Research Council/British Heart Foundation Heart Protection Study find in patients with diabetes mellitus?. ### Response: BP lowering.


Instruction: What study found a 24% reduction in the rate of major CVD events?

Output: Medical Research Council/British Heart Foundation Heart Protection Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study found a 24% reduction in the rate of major CVD events?. ### Response: Medical Research Council/British Heart Foundation Heart Protection Study.