Instruction: What is the CHARM-Alternative Trial?

Output: Effects of candesartan in patients with chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CHARM-Alternative Trial?. ### Response: Effects of candesartan in patients with chronic heart failure.


Instruction: What is candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to?

Output: angiotensin-converting-enzyme inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to?. ### Response: angiotensin-converting-enzyme inhibitors.


Instruction: What is the name of the CHARM-Preserved Trial?

Output: CHARM-Alternative Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the CHARM-Preserved Trial?. ### Response: CHARM-Alternative Trial.


Instruction: What does candesartan have an effect on in patients with heart failure?

Output: mortality and morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does candesartan have an effect on in patients with heart failure?. ### Response: mortality and morbidity.


Instruction: What is the name of the CHARM-Overall programme?

Output: chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the CHARM-Overall programme?. ### Response: chronic heart failure.


Instruction: What are the effects of candesartan on mortality and morbidity in patients with chronic heart failure?

Output: reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects of candesartan on mortality and morbidity in patients with chronic heart failure?. ### Response: reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors.


Instruction: How many articles were published in the Lancet in 2003?

Output: 263

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many articles were published in the Lancet in 2003?. ### Response: 263.


Instruction: Swedberg K, Granger CB, Held P, Olofsson B, Yusuf S, Pfeffer MA; CHARM Investigators and Committees?

Output: 259

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Swedberg K, Granger CB, Held P, Olofsson B, Yusuf S, Pfeffer MA; CHARM Investigators and Committees?. ### Response: 259.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseFebruary 2, 2021 Circulation. 2021;143:e72–e227

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseFebruary 2, 2021 Circulation. 2021;143:e72–e227.


Instruction: What is a reference study that supports the recommendations for management of excessive anticoagulation and Serious Bleeding in patients with prosthetic valves?

Output: Online Data Supplement 37.COR LOE Recommendations2a C-LD1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reference study that supports the recommendations for management of excessive anticoagulation and Serious Bleeding in patients with prosthetic valves?. ### Response: Online Data Supplement 37.COR LOE Recommendations2a C-LD1.


Instruction: Where are references to studies that support the recommendations summarized?

Output: Online Data Supplement 37

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are references to studies that support the recommendations summarized?. ### Response: Online Data Supplement 37.


Instruction: What is reasonable for patients with mechanical valves and uncontrollable bleeding who require immediate reversal of anticoagulation?

Output: administration of 4-factor prothrombin complex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for patients with mechanical valves and uncontrollable bleeding who require immediate reversal of anticoagulation?. ### Response: administration of 4-factor prothrombin complex.


Instruction: What is reasonable if resumption of VKA therapy is not anticipated for 7 days?

Output: adjunctive use of intravenous vitamin K

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable if resumption of VKA therapy is not anticipated for 7 days?. ### Response: adjunctive use of intravenous vitamin K.


Instruction: For patients with mechanical valves and uncontrollable bleeding, adjunctive use of intravenous vitamin K is what?

Output: reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients with mechanical valves and uncontrollable bleeding, adjunctive use of intravenous vitamin K is what?. ### Response: reasonable.


Instruction: What is idarucizumab used for?

Output: dabigatran

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is idarucizumab used for?. ### Response: dabigatran.


Instruction: What is andexanet alfa used for for anti-Xa agents?

Output: anticoagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is andexanet alfa used for for anti-Xa agents?. ### Response: anticoagulants.


Instruction: For patients with bioprosthetic valves or annuloplasty rings who require immediate reversal of anticoagulation what is reasonable?

Output: reversal is indicated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients with bioprosthetic valves or annuloplasty rings who require immediate reversal of anticoagulation what is reasonable?. ### Response: reversal is indicated.


Instruction: What is reasonable for anti-Xa agents?

Output: treatment with idarucizumab (for dabigatran) or andexanet alfa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for anti-Xa agents?. ### Response: treatment with idarucizumab (for dabigatran) or andexanet alfa.


Instruction: What is the benefit of individualized treatment with oral vitamin K in addition to temporary withdrawal of the VKA?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of individualized treatment with oral vitamin K in addition to temporary withdrawal of the VKA?. ### Response: uncertain.


Instruction: What does excessive VKA anticoagulation greatly increase the risk of?

Output: hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does excessive VKA anticoagulation greatly increase the risk of?. ### Response: hemorrhage.


Instruction: What does a rapid decrease in INR to a subtherapeutic level do?

Output: increase the risk of thrombo-embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a rapid decrease in INR to a subtherapeutic level do?. ### Response: increase the risk of thrombo-embolism.


Instruction: Why do patients need im-mediate reversal of VKA?

Output: severe or life-threatening bleeding or the need for an emergency procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do patients need im-mediate reversal of VKA?. ### Response: severe or life-threatening bleeding or the need for an emergency procedure.


Instruction: What is indicated in severe bleeding or the need for an emergency procedure?

Output: reversal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated in severe bleeding or the need for an emergency procedure?. ### Response: reversal.


Instruction: What is a rapid-acting and reliable agent?

Output: prothrombin complex concentrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a rapid-acting and reliable agent?. ### Response: prothrombin complex concentrate.


Instruction: How can vitamin K be considered on an individual basis?

Output: Addition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can vitamin K be considered on an individual basis?. ### Response: Addition.


Instruction: What is idarucizumab?

Output: dabigatran

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is idarucizumab?. ### Response: dabigatran.


Instruction: What is andexanet alfa?

Output: for anti-Xa agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is andexanet alfa?. ### Response: for anti-Xa agents.


Instruction: How long does it take for an anticoagulant to begin to work?

Output: 12 to 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for an anticoagulant to begin to work?. ### Response: 12 to 24 hours.


Instruction: What is a more specific and reliable reversal agent than fresh frozen plasma?

Output: prothrombin complex concentrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a more specific and reliable reversal agent than fresh frozen plasma?. ### Response: prothrombin complex concentrate.


Instruction: What is Vitamin K a cofactor for?

Output: hepatic production

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Vitamin K a cofactor for?. ### Response: hepatic production.


Instruction: How long does the duration of effect last?

Output: 12 to 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does the duration of effect last?. ### Response: 12 to 24 hours.


Instruction: What depends on the route of administration?

Output: Onset of effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What depends on the route of administration?. ### Response: Onset of effect.


Instruction: What should be predicated on the presence of active bleeding, the maintenance dose of the VKA, the magnitude of INR elevation, and the desired range into which to reduce the INR?

Output: the dose given

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be predicated on the presence of active bleeding, the maintenance dose of the VKA, the magnitude of INR elevation, and the desired range into which to reduce the INR?. ### Response: the dose given.


Instruction: What is the recommended intravenous dose?

Output: 10-mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended intravenous dose?. ### Response: 10-mg.


Instruction: What is recommended for life?

Output: A 10-mg intravenous dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for life?. ### Response: A 10-mg intravenous dose.


Instruction: What is a key therapy among African Americans with HFrEF?

Output: HYD/ISDN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key therapy among African Americans with HFrEF?. ### Response: HYD/ISDN.


Instruction: What is underprescribed HYD/ISDN?

Output: a treatment with survivalbene ﬁts isolated to those of self-de ﬁned African-Amer-ican race

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is underprescribed HYD/ISDN?. ### Response: a treatment with survivalbene ﬁts isolated to those of self-de ﬁned African-Amer-ican race.


Instruction: What is underprescribed for African Americans?

Output: HYD/ISDN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is underprescribed for African Americans?. ### Response: HYD/ISDN.


Instruction: What should be a priority to initiate evidence-basedmedicals in all applicable populations?

Output: HYD/ISDN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be a priority to initiate evidence-basedmedicals in all applicable populations?. ### Response: HYD/ISDN.


Instruction: What does cGMP stand for?

Output: cyclic gua-nosine monophosphate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does cGMP stand for?. ### Response: cyclic gua-nosine monophosphate.


Instruction: What is the risk of angioedema with both ACEIs and ARNIs?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of angioedema with both ACEIs and ARNIs?. ### Response: higher.


Instruction: What is used for treating HF in African-Americanpatients?

Output: Clinical guidance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used for treating HF in African-Americanpatients?. ### Response: Clinical guidance.


Instruction: What is a beta-blocker and an aldoste-rone antagonist?

Output: A R N I / A C E I / A R B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a beta-blocker and an aldoste-rone antagonist?. ### Response: A R N I / A C E I / A R B.


Instruction: What is a beta-blocker?

Output: A R N I / A C E I / A R B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a beta-blocker?. ### Response: A R N I / A C E I / A R B.


Instruction: What is an aldoste-rone antagonist?

Output: a beta-blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an aldoste-rone antagonist?. ### Response: a beta-blocker.


Instruction: If stable, follow with titration of what?

Output: HYD/ISDN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If stable, follow with titration of what?. ### Response: HYD/ISDN.


Instruction: What should be done with careful blood pressuremonitoring and close monitoring of other side effects?

Output: titration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be done with careful blood pressuremonitoring and close monitoring of other side effects?. ### Response: titration.


Instruction: What is avail-able as a fixed-dose combination or as individual medi-cations?

Output: fH Y D / I S D Nwith an ARNI, SGLT2 inhibitor, and/or ivabradine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is avail-able as a fixed-dose combination or as individual medi-cations?. ### Response: fH Y D / I S D Nwith an ARNI, SGLT2 inhibitor, and/or ivabradine.


Instruction: In settings of known or hereditary angioe-dema with ACEIs or ARBs, what may be considered?

Output: Avoid ARNIs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In settings of known or hereditary angioe-dema with ACEIs or ARBs, what may be considered?. ### Response: Avoid ARNIs.


Instruction: If the heart rate remains above goal in sinus rhythm,ivabradine might be considered what?

Output: given thepaucity of data in African Americans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the heart rate remains above goal in sinus rhythm,ivabradine might be considered what?. ### Response: given thepaucity of data in African Americans.


Instruction: Given thepaucity of data in African Americans, optimize what dosing preferentially?

Output: beta-blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Given thepaucity of data in African Americans, optimize what dosing preferentially?. ### Response: beta-blocker.


Instruction: What is the risk of HF in African Americans?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of HF in African Americans?. ### Response: higher.


Instruction: What is SGLT2 inhibitor especially important?

Output: pre-HF stage to reduce the onset of the disease in thosewith known diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SGLT2 inhibitor especially important?. ### Response: pre-HF stage to reduce the onset of the disease in thosewith known diabetes.


Instruction: What is especially important in the pre-HF stage?

Output: use of an SGLT2 inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is especially important in the pre-HF stage?. ### Response: use of an SGLT2 inhibitor.


Instruction: What should be assessed and addressed to avoid health inequities in HFrEF outcomes?

Output: Social barriers to GDMT and optimal HFrEF manage-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be assessed and addressed to avoid health inequities in HFrEF outcomes?. ### Response: Social barriers to GDMT and optimal HFrEF manage-ment.


Instruction: What does avoid health inequities in HFrEF outcomes?

Output: Social barriers to GDMT and optimal HFrEF manage-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does avoid health inequities in HFrEF outcomes?. ### Response: Social barriers to GDMT and optimal HFrEF manage-ment.


Instruction: What is a fa l lt r ea t m e n td?

Output: c i s i o n ss h o u l db ed e t e r m i n e di nt h ec o n t e x to fa ni n f o r m e d

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a fa l lt r ea t m e n td?. ### Response: c i s i o n ss h o u l db ed e t e r m i n e di nt h ec o n t e x to fa ni n f o r m e d.


Instruction: What is a nt h ec o n t e x to do?

Output: fa ni n f o r m e d

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a nt h ec o n t e x to do?. ### Response: fa ni n f o r m e d.


Instruction: What does the patient have a discussion about?

Output: risks and bene ﬁts of treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the patient have a discussion about?. ### Response: risks and bene ﬁts of treatment.


Instruction: What is the upper range for inclusion in HF clinical trials?

Output: age 75 /C65 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the upper range for inclusion in HF clinical trials?. ### Response: age 75 /C65 years.


Instruction: What does the decision-making discussion with the patient con-sider?

Output: the risks and bene ﬁts of treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the decision-making discussion with the patient con-sider?. ### Response: the risks and bene ﬁts of treatment.


Instruction: What is the median age of a drug or device in older patients?

Output: 75 /C65 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the median age of a drug or device in older patients?. ### Response: 75 /C65 years.


Instruction: How old are patients who are older than 75?

Output: 75 /C65 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are patients who are older than 75?. ### Response: 75 /C65 years.


Instruction: What type of data are there for drugs or devices?

Output: norandomized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of data are there for drugs or devices?. ### Response: norandomized.


Instruction: What is malformation wit h such tr eatment?

Output: chr onic h yper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is malformation wit h such tr eatment?. ### Response: chr onic h yper tension.


Instruction: What is a treatmen t of chr onic h yper tension?

Output: labetalol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a treatmen t of chr onic h yper tension?. ### Response: labetalol.


Instruction: What is the NICE guideline on h yper tension in adult s?

Output: 1.3.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NICE guideline on h yper tension in adult s?. ### Response: 1.3.6.


Instruction: What should a person do to reduce the amount of salt in their diet?

Output: healt hy eating

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a person do to reduce the amount of salt in their diet?. ### Response: healt hy eating.


Instruction: What if saf e in pr egnancy?

Output: antih yper tensiv e treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What if saf e in pr egnancy?. ### Response: antih yper tensiv e treatment.


Instruction: What unless sustained syst olic blood is less than 110 mmHg?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What unless sustained syst olic blood is less than 110 mmHg?. ### Response: •.


Instruction: What is less than 7 0 mmHg?

Output: sustained diast olic blood pr essur e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less than 7 0 mmHg?. ### Response: sustained diast olic blood pr essur e.


Instruction: What is the w oman's sympt omatic h ypotension?

Output: Hyper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the w oman's sympt omatic h ypotension?. ### Response: Hyper tension.


Instruction: What type of blood pr essur e of 140 mmHg or higher is required?

Output: sustained syst olic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of blood pr essur e of 140 mmHg or higher is required?. ### Response: sustained syst olic.


Instruction: What is required for sustained diast olic blood to be sustained?

Output: 90  mmHg or higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required for sustained diast olic blood to be sustained?. ### Response: 90  mmHg or higher.


Instruction: When using medicines, what should be avoided?

Output: bot h labetalol and nif edipine[3] are not suitable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When using medicines, what should be avoided?. ### Response: bot h labetalol and nif edipine[3] are not suitable.


Instruction: What should you aim for when using medicines to treat h yper tension in pr egnancy?

Output: target blood pr essur e of 135/85  mmHg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should you aim for when using medicines to treat h yper tension in pr egnancy?. ### Response: target blood pr essur e of 135/85  mmHg.


Instruction: What should your target blood pressure be?

Output: 135/85  mmHg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should your target blood pressure be?. ### Response: 135/85  mmHg.


Instruction: What does methyldopa do if bot h labetalol and nif edipine are not suitable?

Output: methyldopa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does methyldopa do if bot h labetalol and nif edipine are not suitable?. ### Response: methyldopa.


Instruction: What is a pre-existing tr eatment, side-eff ect pr ofiles, risks?

Output: fetal eff ects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pre-existing tr eatment, side-eff ect pr ofiles, risks?. ### Response: fetal eff ects.


Instruction: Pre-existing tr eatment, side-eff ect pr ofiles, risks (including fetal eff erts), and t he w oman's pr eference?

Output: methyldopa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pre-existing tr eatment, side-eff ect pr ofiles, risks (including fetal eff erts), and t he w oman's pr eference?. ### Response: methyldopa.


Instruction: Hyper tension in pregnancy: diagnosis and management (NG133) NICE 2023. All right s reserved.

Output: Notice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyper tension in pregnancy: diagnosis and management (NG133) NICE 2023. All right s reserved.. ### Response: Notice.


Instruction: What is the last updat ed 17 April 2023Page 11of 59?

Output: Notice of right s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 17 April 2023Page 11of 59?. ### Response: Notice of right s.


Instruction: What are desirable criteria for timing of referral for transplantation?

Output: specific

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are desirable criteria for timing of referral for transplantation?. ### Response: specific.


Instruction: What can't be made based on current data?

Output: universal recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can't be made based on current data?. ### Response: universal recommendations.


Instruction: Why is the risk of immediate and early posttransplantation higher in ACHD than in acquired heart disease?

Output: increased perioperative mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the risk of immediate and early posttransplantation higher in ACHD than in acquired heart disease?. ### Response: increased perioperative mortality.


Instruction: What is a risk for poor outcomes?

Output: single ventricle anatomy, anatomic complexity, protein-losing enteropathy, or high titers of panel reac-tive antibodies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk for poor outcomes?. ### Response: single ventricle anatomy, anatomic complexity, protein-losing enteropathy, or high titers of panel reac-tive antibodies.


Instruction: What is the risk of an increased perioperative mortality?

Output: immediate and early posttransplan-tation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of an increased perioperative mortality?. ### Response: immediate and early posttransplan-tation.


Instruction: Patients with ACHD do as well as or better than those with what?

Output: ac-quired heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with ACHD do as well as or better than those with what?. ### Response: ac-quired heart disease.


Instruction: What is one of the reasons for poor outcomes?

Output: longer wait times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the reasons for poor outcomes?. ### Response: longer wait times.


Instruction: What puts patients with ACHD at a disadvantage?

Output: The current allocation system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What puts patients with ACHD at a disadvantage?. ### Response: The current allocation system.


Instruction: Rather than priority dictated by the usual accepted risk markers, who is listed by "exception"?

Output: pa-tients with ACHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Rather than priority dictated by the usual accepted risk markers, who is listed by "exception"?. ### Response: pa-tients with ACHD.


Instruction: What is a pro-cess that requires the clinician to argue that the patient warrants higher priority than would be evident by applying the used risk markers?

Output: exception

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pro-cess that requires the clinician to argue that the patient warrants higher priority than would be evident by applying the used risk markers?. ### Response: exception.


Instruction: What is significant mortal-ity for patients with ACHD while on the waitlist?

Output: Surgical alternatives

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is significant mortal-ity for patients with ACHD while on the waitlist?. ### Response: Surgical alternatives.


Instruction: What are some surgical alternatives to transplantation for some patients with CHD?

Output: valve replacement, shunt closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some surgical alternatives to transplantation for some patients with CHD?. ### Response: valve replacement, shunt closure.


Instruction: What is a high risk of for some CHD patients?

Output: periopera-tive mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a high risk of for some CHD patients?. ### Response: periopera-tive mortality.


Instruction: Where should providers consider early referral to when transplantation becomes a necessity?

Output: a transplant center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where should providers consider early referral to when transplantation becomes a necessity?. ### Response: a transplant center.


Instruction: Who has expertise in ACHD transplantation?

Output: transplant center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has expertise in ACHD transplantation?. ### Response: transplant center.


Instruction: What is it advisable to con-sider options for before other high-risk surgery is pursued?

Output: transplantation or ventricular assist de-vice as a backup

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is it advisable to con-sider options for before other high-risk surgery is pursued?. ### Response: transplantation or ventricular assist de-vice as a backup.


Instruction: What is often considered in patients with CHD?

Output: multiorgan transplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often considered in patients with CHD?. ### Response: multiorgan transplantation.


Instruction: What requires a multidisciplinary and comprehensive approach with thoughtful planning and communication among practitioners?

Output: Multi-organ transplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What requires a multidisciplinary and comprehensive approach with thoughtful planning and communication among practitioners?. ### Response: Multi-organ transplantation.


Instruction: How many heart-lung transplants are performed internationally each year?

Output: Fewer than 100

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many heart-lung transplants are performed internationally each year?. ### Response: Fewer than 100.


Instruction: How long is the median survival for heart-lungs transplants?

Output: 3.3 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the median survival for heart-lungs transplants?. ### Response: 3.3 years.


Instruction: What is a condition that causes irreversible pulmonary hypertension?

Output: Eisenmenger syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a condition that causes irreversible pulmonary hypertension?. ### Response: Eisenmenger syndrome.


Instruction: How long is the median survival for heart-lung recipients?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the median survival for heart-lung recipients?. ### Response: 10-year.


Instruction: What is the survival rate for 10-year survival?

Output: 32%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the survival rate for 10-year survival?. ### Response: 32%..


Instruction: Why is survival worse for heart lungs recipients than single organ heart or lung recipients? When was the version of this version downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is survival worse for heart lungs recipients than single organ heart or lung recipients? When was the version of this version downloaded?. ### Response: April 28, 2023.


Instruction: What is the 2014 AHA/ACC NSTE-ACS Guideline e407 535?

Output: Amsterdam et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 AHA/ACC NSTE-ACS Guideline e407 535?. ### Response: Amsterdam et al.


Instruction: What does age and sex have to do with myocardial infarction symptom presentation and in-hospital mortal-ity?

Output: Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does age and sex have to do with myocardial infarction symptom presentation and in-hospital mortal-ity?. ### Response: Association.


Instruction: When did JAMA issue 307:813-22?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 307:813-22?. ### Response: 2012.


Instruction: What is the Global Registry of Acute Coronary Events?

Output: GRACE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Global Registry of Acute Coronary Events?. ### Response: GRACE.


Instruction: What does GACE stand for?

Output: Global Registry of Acute Coronary Events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GACE stand for?. ### Response: Global Registry of Acute Coronary Events.


Instruction: Who excluded older adults and women from recent trials?

Output: Dodd KS, Saczynski JS, Zhao Y , et al.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who excluded older adults and women from recent trials?. ### Response: Dodd KS, Saczynski JS, Zhao Y , et al..


Instruction: What are older adults and women from recent trials of?

Output: acute coronary syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are older adults and women from recent trials of?. ### Response: acute coronary syndromes.


Instruction: What are age and sex differences, and changing trends in the use of evidence-based therapies in acute coronary syndromes?

Output: Age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are age and sex differences, and changing trends in the use of evidence-based therapies in acute coronary syndromes?. ### Response: Age.


Instruction: What is the name of the study that compared age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients?

Output: EARLY ACS trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compared age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients?. ### Response: EARLY ACS trial.


Instruction: When did the Int J Cardiol. 2013 issue 167:2580–7?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Int J Cardiol. 2013 issue 167:2580–7?. ### Response: 2013.


Instruction: How many people were involved in the EARLY ACS trial?

Output: 537

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were involved in the EARLY ACS trial?. ### Response: 537.


Instruction: What is the name of the Acute Coronary Syndromes Israeli Survey?

Output: ACSIS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Acute Coronary Syndromes Israeli Survey?. ### Response: ACSIS.


Instruction: What are the results of coronary angiography in elderly patients with non-ST elevation myocardial infarction?

Output: One-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of coronary angiography in elderly patients with non-ST elevation myocardial infarction?. ### Response: One-year.


Instruction: How long does antithrombotic therapy last in the elderly?

Output: 542

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does antithrombotic therapy last in the elderly?. ### Response: 542.


Instruction: What is an example of antithrombotic therapy in the elderly?

Output: non-ST-segment elevation myocardial infarc-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of antithrombotic therapy in the elderly?. ### Response: non-ST-segment elevation myocardial infarc-tion.


Instruction: What is a possible therapeutic window for antiplatelet therapy?

Output: the elderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible therapeutic window for antiplatelet therapy?. ### Response: the elderly.


Instruction: What is the name of the 8th edition of the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 8th edition of the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines?. ### Response: 2008.


Instruction: What are the hemorrhagic complications of anticoagulant and thrombolytic treatment?

Output: Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133:257S–98S. 544. Lopes RD, Subherwal S, Holmes DN, et al. The association of in-hos-pital major bleeding with short-, intermediate-, and long-term mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the hemorrhagic complications of anticoagulant and thrombolytic treatment?. ### Response: Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133:257S–98S. 544. Lopes RD, Subherwal S, Holmes DN, et al. The association of in-hos-pital major bleeding with short-, intermediate-, and long-term mortality.


Instruction: What is bleeding associated with among older patients with non-ST-segment elevation myocardial infarc-tion?

Output: short-, intermediate-, and long-term mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is bleeding associated with among older patients with non-ST-segment elevation myocardial infarc-tion?. ### Response: short-, intermediate-, and long-term mortality.


Instruction: What is the effect of renal function on the effi-cacy and safety of fondaparinux relative to enoxaparain?

Output: Influence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of renal function on the effi-cacy and safety of fondaparinux relative to enoxaparain?. ### Response: Influence.


Instruction: What is enoxaparin used for in non ST-segment elevation acute coronary syndromes?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin used for in non ST-segment elevation acute coronary syndromes?. ### Response: mortality.


Instruction: What does comorbidity account for in acute myocardial infarction?

Output: excess mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does comorbidity account for in acute myocardial infarction?. ### Response: excess mortality.


Instruction: What is a consensus report from the Bleeding Academic Research Consortium?

Output: Standardized bleeding definitions for cardiovascular clinical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a consensus report from the Bleeding Academic Research Consortium?. ### Response: Standardized bleeding definitions for cardiovascular clinical trials.


Instruction: What is an evolution in cardiovascular care for elderly patients with non-ST-segment elevation?

Output: results from the CRUSADE National Quality Improvement Initiative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an evolution in cardiovascular care for elderly patients with non-ST-segment elevation?. ### Response: results from the CRUSADE National Quality Improvement Initiative.


Instruction: What did the CRUSADE National Quality Improvement Initiative do?

Output: Evolution in cardiovascular care for elderly patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the CRUSADE National Quality Improvement Initiative do?. ### Response: Evolution in cardiovascular care for elderly patients.


Instruction: When did the J Am Coll Cardiol. 2005;46:1479–87?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol. 2005;46:1479–87?. ### Response: 2005.


Instruction: What is the global burden of atrial fibrillation and stroke in regions outside North America and Europe?

Output: epidemiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the global burden of atrial fibrillation and stroke in regions outside North America and Europe?. ### Response: epidemiology.


Instruction: What was the name of the systematic review of the epidemiology?

Output: The global burden of atrial fibrillation and stroke: a systematic review of the epidemiology of atrial fibrillation in regions outside North America and Europe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic review of the epidemiology?. ### Response: The global burden of atrial fibrillation and stroke: a systematic review of the epidemiology of atrial fibrillation in regions outside North America and Europe.


Instruction: Where did Lip GY, Brechin CM, Lane DA live?

Output: North America

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did Lip GY, Brechin CM, Lane DA live?. ### Response: North America.


Instruction: What is the prevalence of atrial fibrillation among older adults?

Output: Racial/ethnic differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of atrial fibrillation among older adults?. ### Response: Racial/ethnic differences.


Instruction: What are the results of the cross-sectional study?

Output: Racial/ethnic differences in the prevalence of atrial fibrillation among older adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the cross-sectional study?. ### Response: Racial/ethnic differences in the prevalence of atrial fibrillation among older adults.


Instruction: Who is Fuster V?

Output: 368

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Fuster V?. ### Response: 368.


Instruction: What is the name of the person who was in the top 10 in the polls?

Output: Estes NA 3rd

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who was in the top 10 in the polls?. ### Response: Estes NA 3rd.


Instruction: What was the last name of a person in the Top 10?

Output: Estes NA 3rd

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the last name of a person in the Top 10?. ### Response: Estes NA 3rd.


Instruction: Who was the first person to win the poll?

Output: Estes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the first person to win the poll?. ### Response: Estes.


Instruction: Which person won the poll in January CT?

Output: Jackman WM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which person won the poll in January CT?. ### Response: Jackman WM.


Instruction: What year were ACCF/AHA/HRS focused updates incorporated into the 2006 guidelines for the management of patients with cancer?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year were ACCF/AHA/HRS focused updates incorporated into the 2006 guidelines for the management of patients with cancer?. ### Response: 2011.


Instruction: What are the 2006 guidelines for the management of patients with atrial fibrillation?

Output: ACC/AHA/ESC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2006 guidelines for the management of patients with atrial fibrillation?. ### Response: ACC/AHA/ESC.


Instruction: What is the name of the Task Force on practice guidelines?

Output: American College of Cardiology Foundation/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on practice guidelines?. ### Response: American College of Cardiology Foundation/American Heart Association.


Instruction: When did Circulation. 2011;123:e269–e367.

Output: 369

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2011;123:e269–e367.. ### Response: 369.


Instruction: What is the prevalence of atrial fibrilla-tion?

Output: age distribution, and gender

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of atrial fibrilla-tion?. ### Response: age distribution, and gender.


Instruction: What is age-related differences in characteristics, performance measures, and treatment trends?

Output: outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is age-related differences in characteristics, performance measures, and treatment trends?. ### Response: outcomes.


Instruction: What are age-related differences in characteristics, performance measures, treatment trends, and outcomes in patients with ischemic stroke?

Output: Racial/ethnic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are age-related differences in characteristics, performance measures, treatment trends, and outcomes in patients with ischemic stroke?. ### Response: Racial/ethnic.


Instruction: When did Circulation. 2010:121:879-891?

Output: 371

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2010:121:879-891?. ### Response: 371.


Instruction: What is the quality of care in women with stroke in the GWTG program?

Output: Quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the quality of care in women with stroke in the GWTG program?. ### Response: Quality.


Instruction: What is the name of the program for women with ischemic stroke in the GWTG program?

Output: Get With The Guidleines-Stroke Steering Committee and Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the program for women with ischemic stroke in the GWTG program?. ### Response: Get With The Guidleines-Stroke Steering Committee and Investigators.


Instruction: When was the last time a woman was diagnosed with atrial fibrillation?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a woman was diagnosed with atrial fibrillation?. ### Response: 2001.


Instruction: What was the age of the woman diagnosed with stroke?

Output: 80

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the age of the woman diagnosed with stroke?. ### Response: 80.


Instruction: What type of atrial fibrillation is more common in women than men?

Output: New-onset

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of atrial fibrillation is more common in women than men?. ### Response: New-onset.


Instruction: What is the name of the disease that affects women?

Output: ischemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects women?. ### Response: ischemic stroke.


Instruction: How is the disease diagnosed?

Output: epidemiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the disease diagnosed?. ### Response: epidemiology.


Instruction: Who is the author of this study?

Output: Laupacis A, Kronmal R, Hart RG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of this study?. ### Response: Laupacis A, Kronmal R, Hart RG.


Instruction: What does SORCan stand for?

Output: Stroke Outcome Research Canada

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SORCan stand for?. ### Response: Stroke Outcome Research Canada.


Instruction: What is the name of the working group that studies the outcome of stroke in those over 80?

Output: Stroke Outcome Research Canada

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the working group that studies the outcome of stroke in those over 80?. ### Response: Stroke Outcome Research Canada.


Instruction: When was the last year of Stroke published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last year of Stroke published?. ### Response: 2008.


Instruction: What is the net clinical benefit of warfarin anticoagulation in atrial fibrillation?

Output: sex differences in presentation, treatment, and outcome. Circulation. 2001;103:2365–2370. 374. Saposnik G, Cote R, Phillips S, Gubitz G, Bayer N, Minuk J, Black S; Stroke Outcome Research Canada (SORCan) Working Group. Stroke outcome in those over 80: a multicenter cohort study across Canada. Stroke. 2008;39:2310–2317. 375

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the net clinical benefit of warfarin anticoagulation in atrial fibrillation?. ### Response: sex differences in presentation, treatment, and outcome. Circulation. 2001;103:2365–2370. 374. Saposnik G, Cote R, Phillips S, Gubitz G, Bayer N, Minuk J, Black S; Stroke Outcome Research Canada (SORCan) Working Group. Stroke outcome in those over 80: a multicenter cohort study across Canada. Stroke. 2008;39:2310–2317. 375.


Instruction: What was the 2009 issue of Ann Intern Med?

Output: 151:297–305

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2009 issue of Ann Intern Med?. ### Response: 151:297–305.


Instruction: Who is Thrift AG, Dewey HM, Macdonell RA, McNeil JJ, Donnan GA?

Output: Thrift AG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Thrift AG, Dewey HM, Macdonell RA, McNeil JJ, Donnan GA?. ### Response: Thrift AG.


Instruction: What is the name of the 2021 guideline for the secondary prevention of Ischemic Strokeprevention?

Output: RCTs381,382

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2021 guideline for the secondary prevention of Ischemic Strokeprevention?. ### Response: RCTs381,382.


Instruction: What are the RCTs381,382 to have no benefit over?

Output: SAPT for recurrent stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the RCTs381,382 to have no benefit over?. ### Response: SAPT for recurrent stroke prevention.


Instruction: What is the exact duration of DAPT at which the risk of hemorrhage begins to outweigh the benefit of stroke prevention?

Output: unknown

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the exact duration of DAPT at which the risk of hemorrhage begins to outweigh the benefit of stroke prevention?. ### Response: unknown.


Instruction: What are older patients804 and those with more severe stroke806?

Output: higher risk of ICH with DAPT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are older patients804 and those with more severe stroke806?. ### Response: higher risk of ICH with DAPT.


Instruction: Patients804 and those with more severe stroke appear to be at higher risk of what with DAPT?

Output: ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients804 and those with more severe stroke appear to be at higher risk of what with DAPT?. ### Response: ICH.


Instruction: What was compared with standard antiplatelet therapy in the TARDIS trial?

Output: Triple antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was compared with standard antiplatelet therapy in the TARDIS trial?. ### Response: Triple antiplatelet therapy.


Instruction: What was found to be no difference in stroke outcomes and a significantly increased risk of bleeding with triple antiplatelet therapy?

Output: standard antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to be no difference in stroke outcomes and a significantly increased risk of bleeding with triple antiplatelet therapy?. ### Response: standard antiplatelet therapy.


Instruction: What may be non-stroke-related indications for DAPT beyond 90 days after stroke?

Output: recent drug-eluting cardiac stent placement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be non-stroke-related indications for DAPT beyond 90 days after stroke?. ### Response: recent drug-eluting cardiac stent placement.


Instruction: What should be clarified to ensure that DAPT is not continued indefinitely beyond the clinical recommended time frame?

Output: these indications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be clarified to ensure that DAPT is not continued indefinitely beyond the clinical recommended time frame?. ### Response: these indications.


Instruction: How long have most ADAPT trials used aspirin and clopi-dogrel in combination?

Output: 21 to 90 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long have most ADAPT trials used aspirin and clopi-dogrel in combination?. ### Response: 21 to 90 days.


Instruction: What should the duration of treatment be?

Output: 21 days, 90 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the duration of treatment be?. ### Response: 21 days, 90 days.


Instruction: What is not fully established?

Output: whether the duration of treatment should be 21 days, 90 days, or some other amount of time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not fully established?. ### Response: whether the duration of treatment should be 21 days, 90 days, or some other amount of time.


Instruction: What is the risk of DAPT among patients with stroke who may be more likely to die?

Output: hemorrhagic transformation of the ischemic stroke or other bleeding complication such as those with large stroke or microhemorrhages remains uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of DAPT among patients with stroke who may be more likely to die?. ### Response: hemorrhagic transformation of the ischemic stroke or other bleeding complication such as those with large stroke or microhemorrhages remains uncertain.


Instruction: What has been studied most extensively in patients with acute CVD?

Output: Pharmacological responsiveness to antiplatelet ther-apy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been studied most extensively in patients with acute CVD?. ### Response: Pharmacological responsiveness to antiplatelet ther-apy.


Instruction: What is the utility of antiplatelet ther-apy?

Output: guiding adjust-ment of antiplatelet medications for long-term prevention remains unclear

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the utility of antiplatelet ther-apy?. ### Response: guiding adjust-ment of antiplatelet medications for long-term prevention remains unclear.


Instruction: How many head-to-head compari-sons of antiplatelet medications have been evaluated for the prevention of recurrent stroke?

Output: Relatively few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many head-to-head compari-sons of antiplatelet medications have been evaluated for the prevention of recurrent stroke?. ### Response: Relatively few.


Instruction: In the existing trials, the benefit of 1 medication over another was shown to be what?

Output: small

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the existing trials, the benefit of 1 medication over another was shown to be what?. ### Response: small.


Instruction: What is the benefit of 1 medication over another?

Output: small

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of 1 medication over another?. ### Response: small.


Instruction: What is a common practice of changing antiplatelet medications in patients already taking 1 medication at the time of stroke?

Output: there is relatively little evidence from RCTs to support the benefit of this practice. Finally, although DOACs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common practice of changing antiplatelet medications in patients already taking 1 medication at the time of stroke?. ### Response: there is relatively little evidence from RCTs to support the benefit of this practice. Finally, although DOACs.


Instruction: There is relatively little evidence from RCTs to support the benefits of what?

Output: antiplate-let medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is relatively little evidence from RCTs to support the benefits of what?. ### Response: antiplate-let medications.


Instruction: DoACs may be beneficial in vascular event reduction in patients with stable CVD?

Output: whether other combinations of medications are equally or more beneficial is not known

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: DoACs may be beneficial in vascular event reduction in patients with stable CVD?. ### Response: whether other combinations of medications are equally or more beneficial is not known.


Instruction: What is COMPASS?

Output: Cardiovascular Outcomes for People Using Antico-agulation Strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is COMPASS?. ### Response: Cardiovascular Outcomes for People Using Antico-agulation Strategies.


Instruction: Do DOACs have any role in secondary stroke prevention for patients with recent noncardioembolic stroke?

Output: whether they have any role in secondary stroke prevention for patients with recent noncardioembolic stroke remains an unanswered question

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do DOACs have any role in secondary stroke prevention for patients with recent noncardioembolic stroke?. ### Response: whether they have any role in secondary stroke prevention for patients with recent noncardioembolic stroke remains an unanswered question.


Instruction: What remains an unanswered question?

Output: whether other combinations of medications are equally or more beneficial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains an unanswered question?. ### Response: whether other combinations of medications are equally or more beneficial.


Instruction: What is needed in the following areas?

Output: further research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed in the following areas?. ### Response: further research.


Instruction: What is the 2018 ACHD Guideline?

Output: cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 ACHD Guideline?. ### Response: cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: cardiovascular risk in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: cardiovascular risk in adults.


Instruction: Who wrote the 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults?

Output: Jensen MD, Ryan DH, Apovian CM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults?. ### Response: Jensen MD, Ryan DH, Apovian CM.


Instruction: What is the name of the group that compiled a report on the 2013 guideline?

Output: American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that compiled a report on the 2013 guideline?. ### Response: American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: How many pages are in Circulation. 2014?

Output: 129:S102–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages are in Circulation. 2014?. ### Response: 129:S102–.


Instruction: How did the 2013 AHA/ACC guideline on lifestyle management reduce cardiovascular risk?

Output: reduce cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the 2013 AHA/ACC guideline on lifestyle management reduce cardiovascular risk?. ### Response: reduce cardiovascular risk.


Instruction: What was the name of the Task Force on Practice Guidelines?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the Task Force on Practice Guidelines?. ### Response: American College of Cardiology/American Heart Association.


Instruction: When was the Circulation. 2014;129:S76-99?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation. 2014;129:S76-99?. ### Response: 2014.


Instruction: What is the 2017 AHA/ACC focused update of?

Output: the 2014 AHA/ACC guideline for the man-agement of patients with valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 AHA/ACC focused update of?. ### Response: the 2014 AHA/ACC guideline for the man-agement of patients with valvular heart disease.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines?

Output: management of high blood pressure in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines?. ### Response: management of high blood pressure in adults.


Instruction: What is the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Instruction: What was the 2017 American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines?

Output: focused update of the 2014 AHA/ACC guideline for the man-agement of patients with valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2017 American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines?. ### Response: focused update of the 2014 AHA/ACC guideline for the man-agement of patients with valvular heart disease.


Instruction: What is the name of the guideline for the management of ST-elevation myocardial infarction?

Output: ACCF/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for the management of ST-elevation myocardial infarction?. ### Response: ACCF/AHA.


Instruction: What are the guidelines for management and quality measures?

Output: Aortic valve and as-cending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the guidelines for management and quality measures?. ### Response: Aortic valve and as-cending aorta.


Instruction: What is the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction a re-port of?

Output: American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction a re-port of?. ### Response: American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.


Instruction: What is a 2017 update of the 2013 ACC/ AHA/HFSA fo-cused update?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 2017 update of the 2013 ACC/ AHA/HFSA fo-cused update?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America.


Instruction: How many times did Circulation. 2013:e362–425?

Output: 127

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times did Circulation. 2013:e362–425?. ### Response: 127.


Instruction: What was the 2013 ACCF/AHA guideline for the management of heart failure?

Output: ACC/AHA/HFSA fo-cused update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2013 ACCF/AHA guideline for the management of heart failure?. ### Response: ACC/AHA/HFSA fo-cused update.


Instruction: What is the name of the Task Force on Clinical Practice Guidelines and the Heart Failure Society of America?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Clinical Practice Guidelines and the Heart Failure Society of America?. ### Response: American College of Cardiology/American Heart Association.


Instruction: Circulation. 2017;136:e137-61.

Output: Failure Society of America

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2017;136:e137-61.. ### Response: Failure Society of America.


Instruction: What year did the ACCF/AHA/HRS update the 2008 guidelines for device-based therapy of cardiac rhythm abnormalities?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the ACCF/AHA/HRS update the 2008 guidelines for device-based therapy of cardiac rhythm abnormalities?. ### Response: 2012.


Instruction: What is the name of the task force on practice guidelines and the Heart Rhythm Society?

Output: American College of Cardiology Foundation/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the task force on practice guidelines and the Heart Rhythm Society?. ### Response: American College of Cardiology Foundation/American Heart Association.


Instruction: What is the acronym for coronary artery bypass graft surgery?

Output: ACCF/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for coronary artery bypass graft surgery?. ### Response: ACCF/AHA.


Instruction: When was the ACCF/AHA guideline published?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ACCF/AHA guideline published?. ### Response: 2014.


Instruction: What is the effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocar -dial infarction?

Output: Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocar -dial infarction: results of the Survival and Ventricular Enlargement Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocar -dial infarction?. ### Response: Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocar -dial infarction: results of the Survival and Ventricular Enlargement Trial.


Instruction: What did the SAVE Investigators do?

Output: Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocar -dial infarction: results of the Survival and Ventricular Enlargement Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the SAVE Investigators do?. ### Response: Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocar -dial infarction: results of the Survival and Ventricular Enlargement Trial.


Instruction: What did ramipril do for survivors of acute myocar -dial infarction with clinical evidence of heart failure?

Output: mortality and morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did ramipril do for survivors of acute myocar -dial infarction with clinical evidence of heart failure?. ### Response: mortality and morbidity.


Instruction: What does AIRE stand for?

Output: Acute Infarction Ramipril Efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AIRE stand for?. ### Response: Acute Infarction Ramipril Efficacy.


Instruction: What is the name of the AIRE Study Investigators?

Output: Acute Infarction Ramipril Efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the AIRE Study Investigators?. ### Response: Acute Infarction Ramipril Efficacy.


Instruction: When was the Acute Infarction Ramipril Efficacy Study published?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Acute Infarction Ramipril Efficacy Study published?. ### Response: 1993.


Instruction: How many patients were treated with trandolapril?

Output: 133

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with trandolapril?. ### Response: 133.


Instruction: What is TRACE?

Output: Trandolapril Cardiac Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TRACE?. ### Response: Trandolapril Cardiac Evaluation.


Instruction: What is the name of the study group that studies myocardial infarction?

Output: Trandolapril Cardiac Evaluation (TRACE) Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studies myocardial infarction?. ### Response: Trandolapril Cardiac Evaluation (TRACE) Study Group.


Instruction: When was the trace study group founded?

Output: 1995

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the trace study group founded?. ### Response: 1995.


Instruction: How many people were in a randomized trial of the angio-tensin-receptor blocker?

Output: 134

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were in a randomized trial of the angio-tensin-receptor blocker?. ### Response: 134.


Instruction: What is valsartan used for in myocardial infarction?

Output: chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is valsartan used for in myocardial infarction?. ### Response: chronic heart failure.


Instruction: What is captopril used for?

Output: morbidity and mortality in chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is captopril used for?. ### Response: morbidity and mortality in chronic heart failure.


Instruction: When was the N Engl J Med 349:1893–906.

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 349:1893–906.. ### Response: 2003.


Instruction: What is the name of the study that investigated the effect of low dose losartan on clinical outcomes in patients with heart failure?

Output: HEAAL study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effect of low dose losartan on clinical outcomes in patients with heart failure?. ### Response: HEAAL study.


Instruction: When did the HEAAL study take place?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the HEAAL study take place?. ### Response: 2009.


Instruction: What was the main effect of candesartan in heart failure patients?

Output: mortality and morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the main effect of candesartan in heart failure patients?. ### Response: mortality and morbidity.


Instruction: What is the CHARM-Overall programme?

Output: Effects of candesartan on mortality and morbidity in patients with chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CHARM-Overall programme?. ### Response: Effects of candesartan on mortality and morbidity in patients with chronic heart failure.


Instruction: What is enalapril versus angiotensin-neprilysin inhibi-tion in heart failure?

Output: Angiotensin-neprilysin inhibi-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enalapril versus angiotensin-neprilysin inhibi-tion in heart failure?. ### Response: Angiotensin-neprilysin inhibi-tion.


Instruction: When was the Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure?. ### Response: 1999.


Instruction: What is the name of the Randomised Intervention Trial in Congestive Heart Failure?

Output: MERIT-HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Randomised Intervention Trial in Congestive Heart Failure?. ### Response: MERIT-HF.


Instruction: When did the Lancet issue 353:2001-7?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet issue 353:2001-7?. ### Response: 1993.


Instruction: What did the carvedilol prospective randomized cumulative survival study do?

Output: morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the carvedilol prospective randomized cumulative survival study do?. ### Response: morbidity.


Instruction: What is the name of the COPERNICUS study?

Output: prospective randomized cumulative survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the COPERNICUS study?. ### Response: prospective randomized cumulative survival.


Instruction: What is eplerenone used for in patients at high risk for hyperkalemia?

Output: Safety and efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is eplerenone used for in patients at high risk for hyperkalemia?. ### Response: Safety and efficacy.


Instruction: What is the name of the study that looked at the effects of spironolactone on mortality in patients with severe heart failure?

Output: Randomized Aldactone Evaluation Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that looked at the effects of spironolactone on mortality in patients with severe heart failure?. ### Response: Randomized Aldactone Evaluation Study Investigators.


Instruction: What study did the investigators of the Randomized Aldactone Evaluation Study do?

Output: N Engl J Med. 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study did the investigators of the Randomized Aldactone Evaluation Study do?. ### Response: N Engl J Med. 1999.


Instruction: What is the name of the research group that studies aneurysmal subarachnoid hem-orrhage in Australia and New Zealand?

Output: The ACROSS Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the research group that studies aneurysmal subarachnoid hem-orrhage in Australia and New Zealand?. ### Response: The ACROSS Group.


Instruction: What is ACROSS?

Output: Australasian Cooperative Research on Subarachnoid HemorrhageStudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACROSS?. ### Response: Australasian Cooperative Research on Subarachnoid HemorrhageStudy.


Instruction: When was the Stroke June 2012?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Stroke June 2012?. ### Response: April 28, 2023.


Instruction: What is the best goal for most adults who are overweight?

Output: ideal body weight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the best goal for most adults who are overweight?. ### Response: ideal body weight.


Instruction: What is expected for every 1-kg reduction in body weight?

Output: 1 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is expected for every 1-kg reduction in body weight?. ### Response: 1 mm Hg.


Instruction: What is a healthy diet DASH dietary pattern Consume a diet rich in fruits, vegetables, whole grains, and low-fat dairy products with reduced content of saturated and total fat?

Output: Dietary Approaches to Stop Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a healthy diet DASH dietary pattern Consume a diet rich in fruits, vegetables, whole grains, and low-fat dairy products with reduced content of saturated and total fat?. ### Response: Dietary Approaches to Stop Hypertension.


Instruction: mm Hg S6.2-6,S6.2-7Optimal goal is 1500 mg/d but aim for at least a 1000-mg/d reduction in most adults?

Output: −3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: mm Hg S6.2-6,S6.2-7Optimal goal is 1500 mg/d but aim for at least a 1000-mg/d reduction in most adults?. ### Response: −3.


Instruction: Enhanced intake of dietary potassiumDietary potassium Aim for what?

Output: 3500–5000 mg/d

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Enhanced intake of dietary potassiumDietary potassium Aim for what?. ### Response: 3500–5000 mg/d.


Instruction: What is a diet rich in?

Output: potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a diet rich in?. ### Response: potassium.


Instruction: How many exercises, 3 sets/exercise, 10 repetitions/set?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many exercises, 3 sets/exercise, 10 repetitions/set?. ### Response: 6.


Instruction: How long is the isometric resistance?

Output: 4 × 2 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the isometric resistance?. ### Response: 4 × 2 min.


Instruction: How much voluntary contraction is there?

Output: 30%–40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much voluntary contraction is there?. ### Response: 30%–40%.


Instruction: What is the maximum voluntary contraction?

Output: 30%–40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum voluntary contraction?. ### Response: 30%–40%.


Instruction: How many drinks daily do men drink?

Output: ≤2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drinks daily do men drink?. ### Response: ≤2.


Instruction: How many mm Hg do women drink daily?

Output: ≤1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mm Hg do women drink daily?. ### Response: ≤1.


Instruction: What is the name of the book that explains how to lower blood pressure with DASH?

Output: Your Guide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that explains how to lower blood pressure with DASH?. ### Response: Your Guide.


Instruction: When was the book released?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the book released?. ### Response: May 3, 2023.


Instruction: Where is the book available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the book available?. ### Response: http://dashdiet.org.


Instruction: How much alcohol does a standard drink in the United States contain?

Output: 14 g

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much alcohol does a standard drink in the United States contain?. ### Response: 14 g.


Instruction: What is the typical amount of alcohol found in 12 oz of regular beer?

Output: 14 g

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the typical amount of alcohol found in 12 oz of regular beer?. ### Response: 14 g.


Instruction: What does S6.2-29DASH stand for?

Output: Dietary Approaches to Stop Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does S6.2-29DASH stand for?. ### Response: Dietary Approaches to Stop Hypertension.


Instruction: What is SBP?

Output: systolic blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SBP?. ### Response: systolic blood pressure.


Instruction: How much alcohol does regular beer typically contain?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much alcohol does regular beer typically contain?. ### Response: 5%.


Instruction: What is defibrillator therapy in adult patients with tetralogy of Fallot?

Output: 2008;10:926–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is defibrillator therapy in adult patients with tetralogy of Fallot?. ### Response: 2008;10:926–.


Instruction: What is a population-based study of late causes of death after pediatric cardiac surgery?

Output: 60-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a population-based study of late causes of death after pediatric cardiac surgery?. ### Response: 60-year.


Instruction: What are the survival prospects and circumstances of death in contemporary adult congenital heart disease patients under follow-up at a large tertiary centre?

Output: thirty years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the survival prospects and circumstances of death in contemporary adult congenital heart disease patients under follow-up at a large tertiary centre?. ### Response: thirty years.


Instruction: Circulation. 2015;132:2118–25.

Output: up at a large tertiary centre

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2015;132:2118–25.. ### Response: up at a large tertiary centre.


Instruction: What is the cause of late deaths after pediatric cardiac surgery?

Output: common congenital heart defects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of late deaths after pediatric cardiac surgery?. ### Response: common congenital heart defects.


Instruction: How many deaths after pediatric cardiac surgery are there?

Output: late deaths after pediatric cardiac surgery: a population-based study. J Am Coll Cardiol. 2007;50:1263–71. S10.8-47

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths after pediatric cardiac surgery are there?. ### Response: late deaths after pediatric cardiac surgery: a population-based study. J Am Coll Cardiol. 2007;50:1263–71. S10.8-47.


Instruction: What is the name of the population-based study?

Output: pro-spective evaluation of risk of sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the population-based study?. ### Response: pro-spective evaluation of risk of sudden cardiac death.


Instruction: How many cases of death are there in adult congenital heart disease?

Output: 55

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of death are there in adult congenital heart disease?. ### Response: 55.


Instruction: What are risk factors for late mortality after the atrial switch operation?

Output: Presence of a ventricular septal defect and the Mustard operation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are risk factors for late mortality after the atrial switch operation?. ### Response: Presence of a ventricular septal defect and the Mustard operation.


Instruction: How many years of follow-up were there in 417 patients at a single center?

Output: thirty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of follow-up were there in 417 patients at a single center?. ### Response: thirty.