Instruction: What was the RR of migraine with aura?

Output: 3.72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of migraine with aura?. ### Response: 3.72.


Instruction: What is the 95% CI of the AHA for CVD prevention in women?

Output: 0.80–1.03

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% CI of the AHA for CVD prevention in women?. ### Response: 0.80–1.03.


Instruction: The AHA endorses the use of aspirin in high-risk women unless contraindicated?

Output: 615

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The AHA endorses the use of aspirin in high-risk women unless contraindicated?. ### Response: 615.


Instruction: In women 65 years of age, if BP is controlled, does benefit from ischemic stroke and MI prevention outweigh the risk of gastrointesti-nal bleeding and hemorrhagic stroke?

Output: outweighs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In women 65 years of age, if BP is controlled, does benefit from ischemic stroke and MI prevention outweigh the risk of gastrointesti-nal bleeding and hemorrhagic stroke?. ### Response: outweighs.


Instruction: What is likely to outweigh complications?

Output: benefit for ischemic stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to outweigh complications?. ### Response: benefit for ischemic stroke prevention.


Instruction: What might aspirin be helpful in reducing risk of stroke?

Output: There are several other subpopulations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might aspirin be helpful in reducing risk of stroke?. ### Response: There are several other subpopulations.


Instruction: Patients with a reduced ankle-brachial index are at higher risk of what?

Output: vascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with a reduced ankle-brachial index are at higher risk of what?. ### Response: vascular.


Instruction: What type of heart failure is referred to NICE 2018?

Output: Chronic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart failure is referred to NICE 2018?. ### Response: Chronic.


Instruction: Who is subject to notice of rights?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is subject to notice of rights?. ### Response: Chronic Heart Failure.


Instruction: How many sites were selected for HCP?

Output: ten

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sites were selected for HCP?. ### Response: ten.


Instruction: Why were the ten sites chosen?

Output: variety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were the ten sites chosen?. ### Response: variety.


Instruction: Where was Tait 2015?

Output: North of England

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was Tait 2015?. ### Response: North of England.


Instruction: How many Qualitative sites were there?

Output: 325

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Qualitative sites were there?. ### Response: 325.


Instruction: How many Qualitative interviews were conducted in North of England in 2015?

Output: 325

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Qualitative interviews were conducted in North of England in 2015?. ### Response: 325.


Instruction: What theory is used to describe the complex adaptive system?

Output: CAS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What theory is used to describe the complex adaptive system?. ### Response: CAS.


Instruction: How many people were interviewed to identify other people involved in their care?

Output: pt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were interviewed to identify other people involved in their care?. ### Response: pt.


Instruction: What method was used to improve interview?

Output: constant comparison method

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What method was used to improve interview?. ### Response: constant comparison method.


Instruction: How many pt networks were there?

Output: N= 50

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pt networks were there?. ### Response: N= 50.


Instruction: How many pt networks did some HCP appear in?

Output: more than one

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pt networks did some HCP appear in?. ### Response: more than one.


Instruction: What was sampled to enrich applicability to palliative care?

Output: HCP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was sampled to enrich applicability to palliative care?. ### Response: HCP.


Instruction: What are the teams providing heart failure care to those with advance d HF in order to plan how best palliative care services can integrate into these teams?

Output: Better understand the behaviour

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the teams providing heart failure care to those with advance d HF in order to plan how best palliative care services can integrate into these teams?. ### Response: Better understand the behaviour.


Instruction: How many Canadian cities in three provinces?

Output: Five

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Canadian cities in three provinces?. ### Response: Five.


Instruction: What is Pt = people with chronic heart failure, HCP = healthcare professional 9.3.3.4?

Output: Abbreviations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Pt = people with chronic heart failure, HCP = healthcare professional 9.3.3.4?. ### Response: Abbreviations.


Instruction: What does HCP stand for?

Output: healthcare professional

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HCP stand for?. ### Response: healthcare professional.


Instruction: What is the definition of a healthcare professional with chronic heart failure?

Output: HCP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of a healthcare professional with chronic heart failure?. ### Response: HCP.


Instruction: How many overarching findings were there in the review?

Output: five

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many overarching findings were there in the review?. ### Response: five.


Instruction: What is the role of specialist heart failure services?

Output: Contact and Access

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of specialist heart failure services?. ### Response: Contact and Access.


Instruction: What were the sub -findings relating to?

Output: (a) challenges/problems, (b) ideas for improvement, and (c) complex transition issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the sub -findings relating to?. ### Response: (a) challenges/problems, (b) ideas for improvement, and (c) complex transition issues.


Instruction: What grading does CerQua l appear with each sub-finding in the summary tables in 9.3.3.5?

Output: quality, including an explanation for the CerQua l grading

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What grading does CerQua l appear with each sub-finding in the summary tables in 9.3.3.5?. ### Response: quality, including an explanation for the CerQua l grading.


Instruction: Relevancy was judged with respect to making recommendations on this particular issue for current NHS specialist and general services?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Relevancy was judged with respect to making recommendations on this particular issue for current NHS specialist and general services?. ### Response: heart failure.


Instruction: Where did some of the evidence come from for current NHS specialist and general services?

Output: studies were conducted in other countries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did some of the evidence come from for current NHS specialist and general services?. ### Response: studies were conducted in other countries.


Instruction: Where were studies conducted before major NHS configuration changes excluded?

Output: US and outside the OECD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where were studies conducted before major NHS configuration changes excluded?. ### Response: US and outside the OECD.


Instruction: How much RR reduction did pharmacological treatment of high triglycerides show?

Output: 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much RR reduction did pharmacological treatment of high triglycerides show?. ### Response: 10%.


Instruction: How many randomized trials were involved in a meta-analysis of data?

Output: 18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized trials were involved in a meta-analysis of data?. ### Response: 18.


Instruction: What was the percentage of reduction in RR in major cardiovascular events?

Output: 13%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the percentage of reduction in RR in major cardiovascular events?. ### Response: 13%.


Instruction: What is the RR reduction in coronary events for fibrate therapy?

Output: 13%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the RR reduction in coronary events for fibrate therapy?. ### Response: 13%.


Instruction: What is a 10% reduction in mortality demonstrated by statins per mmol/l reduction in LDL-C?

Output: vascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 10% reduction in mortality demonstrated by statins per mmol/l reduction in LDL-C?. ### Response: vascular events.


Instruction: What do fibricacid derivatives alter more than LDL-C?

Output: triglyceride-rich lipoproteins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do fibricacid derivatives alter more than LDL-C?. ### Response: triglyceride-rich lipoproteins.


Instruction: What is the main target of statins?

Output: LDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the main target of statins?. ### Response: LDL-C.


Instruction: What was the VA-HIT?

Output: High-DensityLipoprotein Intervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the VA-HIT?. ### Response: High-DensityLipoprotein Intervention Trial.


Instruction: How much did gemfibrozil reduce the risk of major cardiovascular events compared to placebo?

Output: 42%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did gemfibrozil reduce the risk of major cardiovascular events compared to placebo?. ### Response: 42%.


Instruction: What was the RR of fenofibrate compared with placebo in a post hoc analysis of297 individuals with low eGFR and diabetes?

Output: 0.58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of fenofibrate compared with placebo in a post hoc analysis of297 individuals with low eGFR and diabetes?. ### Response: 0.58.


Instruction: What is the name of the diabetes intervention study?

Output: FIELD study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the diabetes intervention study?. ### Response: FIELD study.


Instruction: How was the risk of developing new-onset microalbuminuria compared to placebo?

Output: lowered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the risk of developing new-onset microalbuminuria compared to placebo?. ### Response: lowered.


Instruction: What was the RR of fenofibrate in patients with type 2 diabetes?

Output: 0.87

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of fenofibrate in patients with type 2 diabetes?. ### Response: 0.87.


Instruction: What was a 95% CI?

Output: 1.04–1.28

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a 95% CI?. ### Response: 1.04–1.28.


Instruction: How did the results of the other trials of fibrate therapy in diabetes compare?

Output: None of the othertrials of ﬁbrate therapy in diabetes reported CVD or kidneydisease outcomes for the subgroup of patients with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the results of the other trials of fibrate therapy in diabetes compare?. ### Response: None of the othertrials of ﬁbrate therapy in diabetes reported CVD or kidneydisease outcomes for the subgroup of patients with CKD.


Instruction: What was the name of the large randomized double-blind trial?

Output: The FIELD study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the large randomized double-blind trial?. ### Response: The FIELD study.


Instruction: How many participants were in the FIELD study?

Output: 9795

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants were in the FIELD study?. ### Response: 9795.


Instruction: What is rea-sonable in older adults?

Output: strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rea-sonable in older adults?. ### Response: strategies.


Instruction: What is advised in initiating antihypertensive pharmacotherapy with 2 drugs in older patients?

Output: caution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is advised in initiating antihypertensive pharmacotherapy with 2 drugs in older patients?. ### Response: caution.


Instruction: What type of hypotension may develop in some patients?

Output: orthostatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypotension may develop in some patients?. ### Response: orthostatic.


Instruction: What should be carefully monitored in patients with orthostatic hypotension?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be carefully monitored in patients with orthostatic hypotension?. ### Response: BP.


Instruction: The stepped-care approach defined by the initiation of an-tihypertensive drug therapy with a single agent followed by the sequential titration of the dose and addition of what?

Output: oth-er agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The stepped-care approach defined by the initiation of an-tihypertensive drug therapy with a single agent followed by the sequential titration of the dose and addition of what?. ### Response: oth-er agents.


Instruction: What has been the recommended treatment strategy since the first report of the National High Blood Pressure Education Program?

Output: sequential titration of the dose and addition of oth-er agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been the recommended treatment strategy since the first report of the National High Blood Pressure Education Program?. ### Response: sequential titration of the dose and addition of oth-er agents.


Instruction: What is reason-able in older adults or those at risk?

Output: National High Blood Pressure Education Program.S8.1.6.1-7 This approach is also reason-able in older adults or those at risk or who have a history of hypotension or drug-associated side effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reason-able in older adults or those at risk?. ### Response: National High Blood Pressure Education Program.S8.1.6.1-7 This approach is also reason-able in older adults or those at risk or who have a history of hypotension or drug-associated side effects.


Instruction: What has been used successfully in nearly all hypertension treatment trials?

Output: strat-egy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been used successfully in nearly all hypertension treatment trials?. ### Response: strat-egy.


Instruction: What has not been formally tested against other antihypertensive drug treatment strategies for effec-tiveness?

Output: strat-egy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been formally tested against other antihypertensive drug treatment strategies for effec-tiveness?. ### Response: strat-egy.


Instruction: What are recommendations for lifestyle modifications and drug selec-tion specified in Sections 6.2, 8.1.4, and 8.1.6?

Output: BP Control in Individual Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are recommendations for lifestyle modifications and drug selec-tion specified in Sections 6.2, 8.1.4, and 8.1.6?. ### Response: BP Control in Individual Patients.


Instruction: What should initial drug selections be based on?

Output: trial evidence of treatment effi-cacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should initial drug selections be based on?. ### Response: trial evidence of treatment effi-cacy.


Instruction: What percentage of patients will be able to tolerate the initial drug therapy?

Output: 25% to 50%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients will be able to tolerate the initial drug therapy?. ### Response: 25% to 50%),.


Instruction: What is a subset of patients with a BP of 25% to 50%?

Output: S8.2-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a subset of patients with a BP of 25% to 50%?. ### Response: S8.2-1.


Instruction: What percentage of BP is due to a change in medication or addition of another medi-cation?

Output: 25% to 50%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of BP is due to a change in medication or addition of another medi-cation?. ### Response: 25% to 50%),.


Instruction: What percentage is due because of a decrease in BP?

Output: 25% to 50%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage is due because of a decrease in BP?. ### Response: 25% to 50%),.


Instruction: How is BP monitored?

Output: carefully monitored

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is BP monitored?. ### Response: carefully monitored.


Instruction: Where is the need for follow-up?

Output: Section 8.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the need for follow-up?. ### Response: Section 8.3.


Instruction: What percentage of patients will require additional treatment adjustments?

Output: 25%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients will require additional treatment adjustments?. ### Response: 25%.


Instruction: What can be challenging in a minority of this group?

Output: achievement of goal BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be challenging in a minority of this group?. ### Response: achievement of goal BP.


Instruction: How many medications or medication combinations are ineffective or poorly tolerated?

Output: 2 to 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many medications or medication combinations are ineffective or poorly tolerated?. ### Response: 2 to 3.


Instruction: Some patients may become disillusioned and lost to what?

Output: follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some patients may become disillusioned and lost to what?. ### Response: follow-up.


Instruction: What will some patients identify an alternative health-care provider?

Output: nontraditional healers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will some patients identify an alternative health-care provider?. ### Response: nontraditional healers.


Instruction: What type of care may be effective in a more demanding subset of patients?

Output: team-based care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care may be effective in a more demanding subset of patients?. ### Response: team-based care.


Instruction: What is team-based care?

Output: encouraging coupling of nonpharmacological and pharmacological treatments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is team-based care?. ### Response: encouraging coupling of nonpharmacological and pharmacological treatments.


Instruction: What can be done to improve access to and communication with care providers?

Output: team-based care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be done to improve access to and communication with care providers?. ### Response: team-based care.


Instruction: What should be considered in the setting of medication intolerance?

Output: allowing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered in the setting of medication intolerance?. ### Response: allowing.


Instruction: What could be associated with lower risk of mortality in patients with diabetes mellitus and multivessel disease than PCI?

Output: CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be associated with lower risk of mortality in patients with diabetes mellitus and multivessel disease than PCI?. ### Response: CKD.


Instruction: What is the ongoing FREEDOM trial?

Output: Future Revas-cularization Evaluation in patients with Diabetes mellitus:Optimal management of Multivessel disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ongoing FREEDOM trial?. ### Response: Future Revas-cularization Evaluation in patients with Diabetes mellitus:Optimal management of Multivessel disease.


Instruction: Obese individuals often have reduced what?

Output: diagnostic accu-racy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Obese individuals often have reduced what?. ### Response: diagnostic accu-racy.


Instruction: What is the cause of reduced diagnostic accu-racy for obese patients?

Output: breast tissue or chest girth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of reduced diagnostic accu-racy for obese patients?. ### Response: breast tissue or chest girth.


Instruction: What are the limitations in exercise testing and challenges with imaging through in-creased breast tissue?

Output: reduced diagnostic accu-racy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the limitations in exercise testing and challenges with imaging through in-creased breast tissue?. ### Response: reduced diagnostic accu-racy.


Instruction: What has been reported for obese patients?

Output: reduced diagnostic accu-racy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been reported for obese patients?. ### Response: reduced diagnostic accu-racy.


Instruction: Why is myocardial perfusion PET more accurate than SPECT for the obesepatient?

Output: breast tissue artifact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is myocardial perfusion PET more accurate than SPECT for the obesepatient?. ### Response: breast tissue artifact.


Instruction: What algorithms can help improve my oc-racy?

Output: attenuation-correction algorithmsor prone imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What algorithms can help improve my oc-racy?. ### Response: attenuation-correction algorithmsor prone imaging.


Instruction: Intravenous contrast enhancementimproves image quality in obese patients and results in improved diagnostic certainty for what?

Output: stress echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Intravenous contrast enhancementimproves image quality in obese patients and results in improved diagnostic certainty for what?. ### Response: stress echocardiography.


Instruction: What is the mortality rate for patients on hemodialysisis/H1102220% per year?

Output: 1181–1183

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mortality rate for patients on hemodialysisis/H1102220% per year?. ### Response: 1181–1183.


Instruction: What percentage of deaths among patients are due to a cardiovascular cause?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of deaths among patients are due to a cardiovascular cause?. ### Response: 50%.


Instruction: What are the deaths among these patients due to?

Output: a cardiovascular cause

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the deaths among these patients due to?. ### Response: a cardiovascular cause.


Instruction: To avoid worsening underlying kidney disease, physicians should consider what in pharmacotherapy?

Output: creatinine clearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To avoid worsening underlying kidney disease, physicians should consider what in pharmacotherapy?. ### Response: creatinine clearance.


Instruction: What should physicians apply risk scores for predicting?

Output: the likelihood ofcontrast-induced nephropathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should physicians apply risk scores for predicting?. ### Response: the likelihood ofcontrast-induced nephropathy.


Instruction: What isosmolar contrastagents during angiography?

Output: renal protective strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isosmolar contrastagents during angiography?. ### Response: renal protective strategies.


Instruction: What have studies evaluating the outcomes of revascu-larization in patients with renal disease not applied?

Output: aconsistent definition of renal disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have studies evaluating the outcomes of revascu-larization in patients with renal disease not applied?. ### Response: aconsistent definition of renal disease.


Instruction: How many studies used the Kidney DiseaseOutcome Quality Definition of renal disease grades?

Output: one

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies used the Kidney DiseaseOutcome Quality Definition of renal disease grades?. ### Response: one.


Instruction: What is the grade of creatinine clearance?

Output: Stage 1,creatinine clearance of 90 to 120 mL/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the grade of creatinine clearance?. ### Response: Stage 1,creatinine clearance of 90 to 120 mL/min.


Instruction: What are the grades of renal disease?

Output: Stage 1,creatinine clearance of 90 to 120 mL/min; Stage 2, 60 to 89mL/min; Stage 3, 30 to 59 mL/min; Stage 4, 15 to 29mL/min; and Stage 5, /H1102

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the grades of renal disease?. ### Response: Stage 1,creatinine clearance of 90 to 120 mL/min; Stage 2, 60 to 89mL/min; Stage 3, 30 to 59 mL/min; Stage 4, 15 to 29mL/min; and Stage 5, /H1102.


Instruction: How is renal disease defined?

Output: any creatinineclearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is renal disease defined?. ### Response: any creatinineclearance.


Instruction: What is renal disease defined as?

Output: any creatinineclearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is renal disease defined as?. ### Response: any creatinineclearance.


Instruction: What is the AKIN acronym for?

Output: Acute Kidney Injury Network

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AKIN acronym for?. ### Response: Acute Kidney Injury Network.


Instruction: What were the odds of death for patients with CKD in the COURAGE trial?

Output: 1.48

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the odds of death for patients with CKD in the COURAGE trial?. ### Response: 1.48.


Instruction: What was the risk of MI or new heart failure in patients without kidney disease?

Output: 1.48

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of MI or new heart failure in patients without kidney disease?. ### Response: 1.48.


Instruction: How is lorcaserin approved for the treatment of obesity?

Output: FDA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is lorcaserin approved for the treatment of obesity?. ### Response: FDA.


Instruction: What is the name of the article that FDA approves for the obesity treatment?

Output: lorcaserin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the article that FDA approves for the obesity treatment?. ### Response: lorcaserin.


Instruction: When was the article accessed?

Output: July 12, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the article accessed?. ### Response: July 12, 2012.


Instruction: What is the name of the weight-management drug approved by the FDA?

Output: Qsymia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the weight-management drug approved by the FDA?. ### Response: Qsymia.


Instruction: What type of heart failure is a risk factor for bariatric surgery?

Output: systolic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart failure is a risk factor for bariatric surgery?. ### Response: systolic.


Instruction: Where is Qsymia manufactured?

Output: Bethesda, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Qsymia manufactured?. ### Response: Bethesda, MD.


Instruction: What drug is approved for weight management?

Output: Qsymia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is approved for weight management?. ### Response: Qsymia.


Instruction: When was the FDA's announcement made?

Output: July 2, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the FDA's announcement made?. ### Response: July 2, 2012.


Instruction: How many obese patients were treated with Orlistat in 2005?

Output: 246

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many obese patients were treated with Orlistat in 2005?. ### Response: 246.


Instruction: What is a pilot study of heart failure?

Output: Effect of Orlistat

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pilot study of heart failure?. ### Response: Effect of Orlistat.


Instruction: What is the name of the pilot study?

Output: Congest Heart Fail

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pilot study?. ### Response: Congest Heart Fail.


Instruction: How many people were enrolled in the trial?

Output: 246

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the trial?. ### Response: 246.


Instruction: What is the impact of body composition, fat distribution and sustained weight loss on cardiac function in obesity?

Output: Bariatric surgery im-proves cardiac function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of body composition, fat distribution and sustained weight loss on cardiac function in obesity?. ### Response: Bariatric surgery im-proves cardiac function.


Instruction: Int J Cardiol. 2012;159:128-133. doi: 10.1016/j.ijcard.2011.02.036.

Output: 246

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol. 2012;159:128-133. doi: 10.1016/j.ijcard.2011.02.036.. ### Response: 246.


Instruction: Who represents the American Heart Association Council on Cardiovascular Nursing, Council on Clinical Cardiology, and Council on Nutrition, Physical Activity, and Metabolism?

Output: SJ, Schocken DD, Whellan DJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who represents the American Heart Association Council on Cardiovascular Nursing, Council on Clinical Cardiology, and Council on Nutrition, Physical Activity, and Metabolism?. ### Response: SJ, Schocken DD, Whellan DJ.


Instruction: Who represents Interdisciplinary Council on Quality of Care and Outcomes Research?

Output: American Heart Association Council on Cardiovascular Nursing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who represents Interdisciplinary Council on Quality of Care and Outcomes Research?. ### Response: American Heart Association Council on Cardiovascular Nursing.


Instruction: What organization promotes self-care in people with heart failure?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What organization promotes self-care in people with heart failure?. ### Response: American Heart Association.


Instruction: What is the name of the scientific statement from the American Heart Association?

Output: State of the science: promoting self-care in persons with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the scientific statement from the American Heart Association?. ### Response: State of the science: promoting self-care in persons with heart failure.


Instruction: When was Circulation.120:1141–1163. doi: 10.1161/CIRCULATIONAHA.109.192628?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation.120:1141–1163. doi: 10.1161/CIRCULATIONAHA.109.192628?. ### Response: 2009.


Instruction: What does bariatric surgery do in morbid obese patients with severe cardiomyopathy?

Output: im-proves cardiac function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does bariatric surgery do in morbid obese patients with severe cardiomyopathy?. ### Response: im-proves cardiac function.


Instruction: What is the effect of obesity on quality of life and depression in obese patients?

Output: cardiac function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of obesity on quality of life and depression in obese patients?. ### Response: cardiac function.


Instruction: What is the impact of obesity on quality of life and depression in patients with heart failure?

Output: 251

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of obesity on quality of life and depression in patients with heart failure?. ### Response: 251.


Instruction: When did Eur J Heart Fail. 2006:8:750–755. doi: 10.1016/j.ejheart.2006.02.004?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Heart Fail. 2006:8:750–755. doi: 10.1016/j.ejheart.2006.02.004?. ### Response: 2006.


Instruction: What does obesity have an impact on?

Output: cardiac function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does obesity have an impact on?. ### Response: cardiac function.


Instruction: In what year was J Gen Intern Med published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was J Gen Intern Med published?. ### Response: 2012.


Instruction: What is the name of the journal that published a study on exercise training in heart failure?

Output: Heart Fail Rev.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published a study on exercise training in heart failure?. ### Response: Heart Fail Rev..


Instruction: How many people were diagnosed with heart failure in 2000?

Output: 253

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were diagnosed with heart failure in 2000?. ### Response: 253.


Instruction: What did Barbour KA and Miller NH do in relation to exercise?

Output: Adherence to exercise training in heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Barbour KA and Miller NH do in relation to exercise?. ### Response: Adherence to exercise training in heart failure.


Instruction: What did Silverman HS, Pfeifer MP say about anti-inflammatory agents during acute myocardial infarction?

Output: Relation between use of anti-inflammatory agents and left ventricular free wall rupture

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Silverman HS, Pfeifer MP say about anti-inflammatory agents during acute myocardial infarction?. ### Response: Relation between use of anti-inflammatory agents and left ventricular free wall rupture.


Instruction: What did Imazio M, Negro A, Belli R, et al. say about pericarditis following acute myofascial infarct treated by primary percutaneous coronary intervention?

Output: Frequency and prognostic significance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Imazio M, Negro A, Belli R, et al. say about pericarditis following acute myofascial infarct treated by primary percutaneous coronary intervention?. ### Response: Frequency and prognostic significance.


Instruction: How is acute myocardial infarction treated?

Output: primary percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is acute myocardial infarction treated?. ### Response: primary percutaneous coronary intervention.


Instruction: What is primary percutaneous coronary intervention used for?

Output: pericarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is primary percutaneous coronary intervention used for?. ### Response: pericarditis.


Instruction: What did the Work Group determine the increased risks outweigh unproven benefits of statins?

Output: lack of evidence of added benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group determine the increased risks outweigh unproven benefits of statins?. ### Response: lack of evidence of added benefit.


Instruction: What recommendation was made by the Working Group?

Output: Weak against

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What recommendation was made by the Working Group?. ### Response: Weak against.


Instruction: Why was the "Weak against" recommendation made?

Output: lack of evidence of added benefit with higher dose statins, the Work Group determined the increased risks outweigh unproven benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the "Weak against" recommendation made?. ### Response: lack of evidence of added benefit with higher dose statins, the Work Group determined the increased risks outweigh unproven benefits.


Instruction: What is needed to compare statins for primary prevention to?

Output: moderate -dose statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to compare statins for primary prevention to?. ### Response: moderate -dose statins.


Instruction: What should be the focus of the research?

Output: direct comparisons between moderate - and high-dose statins in similar populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the focus of the research?. ### Response: direct comparisons between moderate - and high-dose statins in similar populations.


Instruction: How should populations be stratified?

Output: by CV risk scoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should populations be stratified?. ### Response: by CV risk scoring.


Instruction: What is the name of the device used to close perimem-branous ventricular septal defects with aneurysmal tissue?

Output: Amplazter Duct Occluder I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the device used to close perimem-branous ventricular septal defects with aneurysmal tissue?. ### Response: Amplazter Duct Occluder I.


Instruction: What are the results of using the Amplazter Duct Occluder I?

Output: lessons learned and medium term fol-low up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of using the Amplazter Duct Occluder I?. ### Response: lessons learned and medium term fol-low up.


Instruction: In what year did Catheter Cardiovasc Interv. 80:895-903.

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Catheter Cardiovasc Interv. 80:895-903.. ### Response: 2012.


Instruction: What is the term fol-low up?

Output: medium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term fol-low up?. ### Response: medium.


Instruction: Catheter Cardiovasc Interv. 2012;80:895-903. S4.1.3-17. Masura J, Gao W, Gavora P, et al. Percutaneous closure of perimembranous ventricular septal defects with the eccentric Amplatzer device: multicenter follow-up study?

Output: Amplatzer device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Catheter Cardiovasc Interv. 2012;80:895-903. S4.1.3-17. Masura J, Gao W, Gavora P, et al. Percutaneous closure of perimembranous ventricular septal defects with the eccentric Amplatzer device: multicenter follow-up study?. ### Response: Amplatzer device.


Instruction: Tatsuno K, Konno S, Sakakibara S. Ventricular septal defect with what?

Output: aortic insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tatsuno K, Konno S, Sakakibara S. Ventricular septal defect with what?. ### Response: aortic insufficiency.


Instruction: What is a Ventricular septal defect with aortic insufficiency?

Output: Atrioventricular Septal Defect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Ventricular septal defect with aortic insufficiency?. ### Response: Atrioventricular Septal Defect.


Instruction: What is the 2014 AHA/ACC guideline for the management of?

Output: patients with valvular heart di-sease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 AHA/ACC guideline for the management of?. ### Response: patients with valvular heart di-sease.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?

Output: management of patients with valvular heart di-sease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?. ### Response: management of patients with valvular heart di-sease.


Instruction: What is the 2014 AHA/ACC guideline for the management of patients with valvular heart di-sease?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 AHA/ACC guideline for the management of patients with valvular heart di-sease?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines report on?

Output: AHA/ACC guideline for the management of patients with valvular heart di-sease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines report on?. ### Response: AHA/ACC guideline for the management of patients with valvular heart di-sease.


Instruction: What was the name of the report?

Output: American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the report?. ### Response: American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: How did the Task Force of Practice Guidelines treat di-sease?

Output: management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the Task Force of Practice Guidelines treat di-sease?. ### Response: management.


Instruction: What is the difference between replacement and repair?

Output: replacement superior

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between replacement and repair?. ### Response: replacement superior.


Instruction: What are the results of reoperation for left atrioventricular valve regurgitation?

Output: Long-term results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of reoperation for left atrioventricular valve regurgitation?. ### Response: Long-term results.


Instruction: What is the Surgical implications of pulmonary hypertension in congenital heart disease?

Output: S4.1.4-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Surgical implications of pulmonary hypertension in congenital heart disease?. ### Response: S4.1.4-5.


Instruction: What is a defect in the atrioventricular septal defect?

Output: aortic insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a defect in the atrioventricular septal defect?. ### Response: aortic insufficiency.


Instruction: What is a congenital cardiac anomaly associated with?

Output: left to right shunt and severe pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a congenital cardiac anomaly associated with?. ### Response: left to right shunt and severe pulmonary hypertension.


Instruction: What is anatomic observations on complete form of persistent common atrioventricular canal?

Output: special refer -ence to atrioventricular valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is anatomic observations on complete form of persistent common atrioventricular canal?. ### Response: special refer -ence to atrioventricular valves.


Instruction: What do anatomic observations on complete form of persistent common atrioventricular canal with special refer ence to?

Output: atrioventricular valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do anatomic observations on complete form of persistent common atrioventricular canal with special refer ence to?. ### Response: atrioventricular valves.


Instruction: What is the problem of mitral valve incompetence?

Output: Surgical repair of the partial form of persistent common atrioventricular canal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the problem of mitral valve incompetence?. ### Response: Surgical repair of the partial form of persistent common atrioventricular canal.


Instruction: What is a special ref-erence to the problem of mitral valve incompetence?

Output: Surgical repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a special ref-erence to the problem of mitral valve incompetence?. ### Response: Surgical repair.


Instruction: Circulation. 1965;31 suppl 1:131–5.

Output: Downloaded

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 1965;31 suppl 1:131–5.. ### Response: Downloaded.


Instruction: What is a pilot investigation of cardiopulmonary bypass?

Output: TAS heparin management test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pilot investigation of cardiopulmonary bypass?. ### Response: TAS heparin management test.


Instruction: What is the name of the one-step point-of-care whole blood anti-factor-Xa clottingassay?

Output: Heptest-POC-Hi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the one-step point-of-care whole blood anti-factor-Xa clottingassay?. ### Response: Heptest-POC-Hi.


Instruction: How is Heptest-POC-Hi used?

Output: Heparin moni-toring during cardiopulmonary bypass surgery using theone-step point-of-care whole blood anti-factor-Xa clottingassay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is Heptest-POC-Hi used?. ### Response: Heparin moni-toring during cardiopulmonary bypass surgery using theone-step point-of-care whole blood anti-factor-Xa clottingassay.


Instruction: What is heparindosing and monitoring for?

Output: cardiopulmonary bypass

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heparindosing and monitoring for?. ### Response: cardiopulmonary bypass.


Instruction: What is the comparison of techniques with measurement of subclinicalplasma coagulation?

Output: Heparindosing and monitoring for cardiopulmonary bypass

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the comparison of techniques with measurement of subclinicalplasma coagulation?. ### Response: Heparindosing and monitoring for cardiopulmonary bypass.


Instruction: What does not correlate with postoperative bleeding after cardiac surgery?

Output: heparin in wholeblood heparin concentration-based management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not correlate with postoperative bleeding after cardiac surgery?. ### Response: heparin in wholeblood heparin concentration-based management.


Instruction: What is a comparison ofACT point of care measurements?

Output: repeatability and agree-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison ofACT point of care measurements?. ### Response: repeatability and agree-ment.


Instruction: What is a new point of care heparin test for cardiopulmonarybypass?

Output: TAS heparin management test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new point of care heparin test for cardiopulmonarybypass?. ### Response: TAS heparin management test.


Instruction: What is the name of the test?

Output: Sonoclot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the test?. ### Response: Sonoclot.


Instruction: How does theage of a blood sample affect its activated clotting time?

Output: Changing systems for measuringactivated clotting times: impact on the clinical practice ofheparin anticoagulation during cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does theage of a blood sample affect its activated clotting time?. ### Response: Changing systems for measuringactivated clotting times: impact on the clinical practice ofheparin anticoagulation during cardiac surgery.


Instruction: How many different devices were compared?

Output: eight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many different devices were compared?. ### Response: eight.


Instruction: How many different devices are there?

Output: eight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many different devices are there?. ### Response: eight.


Instruction: What are not interchangeable when followingcardiacryopulmonary bypass protocols?

Output: Activated clotting time systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are not interchangeable when followingcardiacryopulmonary bypass protocols?. ### Response: Activated clotting time systems.


Instruction: What is heparinmonitoring during during cardiac surgery?

Output: activated coagulation time measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heparinmonitoring during during cardiac surgery?. ### Response: activated coagulation time measurements.


Instruction: What is part 2 of calculating the overestimation of hemeparin by the activated clotting time?

Output: Heparinmonitoring during cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is part 2 of calculating the overestimation of hemeparin by the activated clotting time?. ### Response: Heparinmonitoring during cardiac surgery.


Instruction: What is the impact of times on the clinical practice of heparin anticoagulation during cardiac surgery?

Output: activated clotting times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of times on the clinical practice of heparin anticoagulation during cardiac surgery?. ### Response: activated clotting times.


Instruction: What is a novel thrombe-lastograph tissue factor/kaolin assay for monitoring?

Output: Sonoclot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a novel thrombe-lastograph tissue factor/kaolin assay for monitoring?. ### Response: Sonoclot.


Instruction: What is the name of the test used to measure activatedclotting time for heparin and aprotinin applica-tion?

Output: Sonoclot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the test used to measure activatedclotting time for heparin and aprotinin applica-tion?. ### Response: Sonoclot.


Instruction: What is another name for Sonoclot?

Output: aprotinin-insensitive test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Sonoclot?. ### Response: aprotinin-insensitive test.


Instruction: In what year did Eur J Cardiothorac Surg publish?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Eur J Cardiothorac Surg publish?. ### Response: 2006.


Instruction: What is detection bias?

Output: lack of blinding of patients and healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is detection bias?. ### Response: lack of blinding of patients and healthcare professionals.


Instruction: What should not be aware of the arm to which patients are allocated?

Output: detection bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be aware of the arm to which patients are allocated?. ### Response: detection bias.


Instruction: Be aware of the arm to which patients are allocated?

Output: indirectness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Be aware of the arm to which patients are allocated?. ### Response: indirectness.


Instruction: Knowledge of the group can influence:  the experience of the placebo effect  performan ce in what?

Output: outcome measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Knowledge of the group can influence:  the experience of the placebo effect  performan ce in what?. ### Response: outcome measures.


Instruction: What can contribute to systematic bias?

Output: Knowledge of the group can influence:   the experience of the placebo effect   performan ce in outcome measures   the level of care and attention received, and   the methods of measurement or analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can contribute to systematic bias?. ### Response: Knowledge of the group can influence:   the experience of the placebo effect   performan ce in outcome measures   the level of care and attention received, and   the methods of measurement or analysis.


Instruction: Attrition bias results from an unaccounted for loss of data beyond a certain level (a differential of 10% between groups).

Output: Attrition bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Attrition bias results from an unaccounted for loss of data beyond a certain level (a differential of 10% between groups).. ### Response: Attrition bias.


Instruction: Loss of data can occur when participants are what?

Output: compulsorily withdrawn from a group by the researchers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Loss of data can occur when participants are what?. ### Response: compulsorily withdrawn from a group by the researchers.


Instruction: What can happen when participants are compulsorily withdrawn from a group by the researchers?

Output: Loss of data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can happen when participants are compulsorily withdrawn from a group by the researchers?. ### Response: Loss of data.


Instruction: What can occur when participants do not attend assessment sessions?

Output: Loss of data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can occur when participants do not attend assessment sessions?. ### Response: Loss of data.


Instruction: What can result from missing data from groups?

Output: systematic attrition bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can result from missing data from groups?. ### Response: systematic attrition bias.


Instruction: What type of reporting can result in systematic attrition bias?

Output: Selective outcome reporting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of reporting can result in systematic attrition bias?. ### Response: Selective outcome reporting.


Instruction: What can also lead to bias?

Output: of the results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can also lead to bias?. ### Response: of the results.


Instruction: What can distort the overall impression of efficacy?

Output: bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can distort the overall impression of efficacy?. ### Response: bias.


Instruction: What is used to avoid carry over effects in crossover trials?

Output: Lack of washout periods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to avoid carry over effects in crossover trials?. ### Response: Lack of washout periods.


Instruction: What is recruitment bias in cluster -randomised trials called?

Output: Indirectness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recruitment bias in cluster -randomised trials called?. ### Response: Indirectness.


Instruction: Indirectness refers to the extent to which populations, interventions, comparisons and outcome measures are dissimilar to those defined in what criteria?

Output: inclusion criteria for the reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Indirectness refers to the extent to which populations, interventions, comparisons and outcome measures are dissimilar to those defined in what criteria?. ### Response: inclusion criteria for the reviews.


Instruction: What is important when these differences are expected to contribute to a difference in effect size or may affect the effect size?

Output: Indirectness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important when these differences are expected to contribute to a difference in effect size or may affect the effect size?. ### Response: Indirectness.


Instruction: How was the risk of bias assessed for each outcome?

Output: each outcome had its indirectness assessed within each study first

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the risk of bias assessed for each outcome?. ### Response: each outcome had its indirectness assessed within each study first.


Instruction: What was given a score if there were no sources of indirectness?

Output: 0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was given a score if there were no sources of indirectness?. ### Response: 0.


Instruction: What was given a rating of 0 if there were no sources of indirectness?

Output: indirectness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was given a rating of 0 if there were no sources of indirectness?. ### Response: indirectness.


Instruction: If there was indirectness in just 1 source, what rating was given?

Output: −1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If there was indirectness in just 1 source, what rating was given?. ### Response: −1.


Instruction: What was the rating given if indirectness was in 2 or more sources?

Output: −2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the rating given if indirectness was in 2 or more sources?. ### Response: −2.


Instruction: How serious was the indirectness in 2 or more sources rated?

Output: −2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How serious was the indirectness in 2 or more sources rated?. ### Response: −2.


Instruction: What was calculated across all studies contributing to the outcome by taking into account study precision?

Output: A weighted average score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was calculated across all studies contributing to the outcome by taking into account study precision?. ### Response: A weighted average score.


Instruction: What does Inconsistency refer to?

Output: an unexplained heterogeneity of results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Inconsistency refer to?. ### Response: an unexplained heterogeneity of results.


Instruction: What would the overall score for an outcome tend to be?

Output: −1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would the overall score for an outcome tend to be?. ### Response: −1.


Instruction: What refers to an unexplained heterogeneity of results for an outcome across different outcomes?

Output: Inconsistency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What refers to an unexplained heterogeneity of results for an outcome across different outcomes?. ### Response: Inconsistency.


Instruction: What is the effect of blood pressure control on diabetic microvascular complications in patients with hypertension and type 2 diabetes?

Output: Estacio RO, Jeffers BW, Gifford N et al. Effect of blood pressure control ondiabetic microvascular complications in patients with hypertension andtype 2 diabetes. Diabetes Care 2000; 23(Suppl 2): B54– B64.184

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of blood pressure control on diabetic microvascular complications in patients with hypertension and type 2 diabetes?. ### Response: Estacio RO, Jeffers BW, Gifford N et al. Effect of blood pressure control ondiabetic microvascular complications in patients with hypertension andtype 2 diabetes. Diabetes Care 2000; 23(Suppl 2): B54– B64.184.


Instruction: What is irbesartan used for?

Output: IgAnephropathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is irbesartan used for?. ### Response: IgAnephropathy.


Instruction: What is the angiotensin-receptor antagonist irbesartan used for?

Output: Renoprotective effect of theangiotensin-receptor antagonist irbesartan in patients with nephropathydue to type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the angiotensin-receptor antagonist irbesartan used for?. ### Response: Renoprotective effect of theangiotensin-receptor antagonist irbesartan in patients with nephropathydue to type 2 diabetes.


Instruction: What type of patients have nephropathy due to type 2 diabetes?

Output: type 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients have nephropathy due to type 2 diabetes?. ### Response: type 1.


Instruction: When was ramipril published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was ramipril published?. ### Response: 2010.


Instruction: What is the name of the study conducted by the Heart Outcomes Prevention Evaluation Study Investigators?

Output: EUROPA trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study conducted by the Heart Outcomes Prevention Evaluation Study Investigators?. ### Response: EUROPA trial.


Instruction: What was the N Engl JMed 2000: 342: 145–153.186?

Output: The Heart Outcomes Prevention Evaluation Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl JMed 2000: 342: 145–153.186?. ### Response: The Heart Outcomes Prevention Evaluation Study Investigators.


Instruction: When was the PROGRESS study conducted?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the PROGRESS study conducted?. ### Response: 2007.


Instruction: What is the name of the study that evaluated the effectiveness of angiotensin-converting enzyme inhibitor therapy in patients with coronary disease?

Output: EUROPA trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the effectiveness of angiotensin-converting enzyme inhibitor therapy in patients with coronary disease?. ### Response: EUROPA trial.


Instruction: What is PEACE?

Output: Prevention of Events with ACEinhibition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PEACE?. ### Response: Prevention of Events with ACEinhibition.


Instruction: When was PEACE trial conducted?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was PEACE trial conducted?. ### Response: 2006.


Instruction: What is the effect of albuminuria oncardiovascular risk in patients with stable coronary artery disease?

Output: Inﬂuence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of albuminuria oncardiovascular risk in patients with stable coronary artery disease?. ### Response: Inﬂuence.


Instruction: When was Circulation 2007;116:2687-2693.189?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation 2007;116:2687-2693.189?. ### Response: 2007.


Instruction: What is angiotensin-converting enzyme inhibitor?

Output: ramipril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is angiotensin-converting enzyme inhibitor?. ### Response: ramipril.


Instruction: What is not modified by mild to moderaterenal insufficiency?

Output: The cardioprotective effects ofthe angiotensin-converting enzyme inhibitor perindopril in patients withstable coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not modified by mild to moderaterenal insufficiency?. ### Response: The cardioprotective effects ofthe angiotensin-converting enzyme inhibitor perindopril in patients withstable coronary artery disease.


Instruction: What is the name of the trial that examined the effects of fosinopril andpravastatin on cardiovascular events?

Output: EUROPA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that examined the effects of fosinopril andpravastatin on cardiovascular events?. ### Response: EUROPA.


Instruction: What is the name of the Hong Kong study using valsartan in IgAnephropathy?

Output: HKVIN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Hong Kong study using valsartan in IgAnephropathy?. ### Response: HKVIN.


Instruction: What are the names of the subjects with microalbuminuria?

Output: Asselbergs FW, Diercks GF, Hillege HL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the subjects with microalbuminuria?. ### Response: Asselbergs FW, Diercks GF, Hillege HL.


Instruction: What is benazepril used for?

Output: advanced chronic renal insufﬁciency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is benazepril used for?. ### Response: advanced chronic renal insufﬁciency.


Instruction: What is the glomerular filtration rate innormoalbuminuric patients?

Output: Low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the glomerular filtration rate innormoalbuminuric patients?. ### Response: Low.


Instruction: When was the N Engl J Med 354:131-140.193?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 354:131-140.193?. ### Response: 2006.


Instruction: What is an indicator of more advanced glomerular lesions in type 1 diabetic patients?

Output: Low glomerular ﬁltration rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an indicator of more advanced glomerular lesions in type 1 diabetic patients?. ### Response: Low glomerular ﬁltration rate.


Instruction: Diabetes 2003; 52: 1036-1040.195 What is renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetesmellitus?

Output: Low glomerular ﬁltration rate innormoalbuminuric type 1 diabetic patients: an indicator of moreadvanced glomerular lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diabetes 2003; 52: 1036-1040.195 What is renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetesmellitus?. ### Response: Low glomerular ﬁltration rate innormoalbuminuric type 1 diabetic patients: an indicator of moreadvanced glomerular lesions.


Instruction: What is retinopathy among adults with type 2 diabetesmellitus?

Output: Renal insufﬁciency in the absenceof albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is retinopathy among adults with type 2 diabetesmellitus?. ### Response: Renal insufﬁciency in the absenceof albuminuria.


Instruction: What is nonalbuminuric renalinsufficiency related to?

Output: an increase in intrarenalvascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is nonalbuminuric renalinsufficiency related to?. ### Response: an increase in intrarenalvascular disease.


Instruction: What type of diabetes is seen in patients with new-onset microalbuminuria?

Output: type 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes is seen in patients with new-onset microalbuminuria?. ### Response: type 1.


Instruction: In patients with type 1 diabetes, what is the development of?

Output: advanced chronic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with type 1 diabetes, what is the development of?. ### Response: advanced chronic.


Instruction: What is an aetiologic andprognostic factor in coronary heart disease?

Output: Depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an aetiologic andprognostic factor in coronary heart disease?. ### Response: Depression.


Instruction: How many participants participated in a meta-analysis of 6362events in 54 observational studies?

Output: 146 538

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants participated in a meta-analysis of 6362events in 54 observational studies?. ### Response: 146 538.


Instruction: What is the association between anxiety and depression and unhealthy lifestyle?

Output: patients at risk of cardiovasculardisease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between anxiety and depression and unhealthy lifestyle?. ### Response: patients at risk of cardiovasculardisease.


Instruction: Anxiety and depression are associated with unhealthy lifestyle in patients at risk of what?

Output: cardiovasculardisease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anxiety and depression are associated with unhealthy lifestyle in patients at risk of what?. ### Response: cardiovasculardisease.


Instruction: Atherosclerosis. 2005;178:339–44.686 What affect completion rates and clinical outcomes incardiac rehabilitation?

Output: Depress ivesymptoms and sex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atherosclerosis. 2005;178:339–44.686 What affect completion rates and clinical outcomes incardiac rehabilitation?. ### Response: Depress ivesymptoms and sex.


Instruction: Prev Cardiol. 2007;10:15–21.687

Output: R

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prev Cardiol. 2007;10:15–21.687. ### Response: R.


Instruction: What study did Haas D, Pipkin S, et al. find about depression and medication adherence in outpatients with coronary heart disease?

Output: Heart andSoul Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study did Haas D, Pipkin S, et al. find about depression and medication adherence in outpatients with coronary heart disease?. ### Response: Heart andSoul Study.


Instruction: What did Kronish IM, Rieckmann N, Halm EA, and others find about adherence to secondary prevention behaviors after acute coronary syndromes?

Output: Persistent depressionaffects adherence to secondary prevention behaviors after acutecoronary syndromes. J Gen Intern Med. 2006;21:1178–83.689. McKellar JD, Humphreys K, Piette JD. Depression increases diabetessymptoms by complicating patients’ self-care adherence. D iabetesEduc. 2004;30:485–92.690. Rieckmann N, Kronish IM, Haas D, et al. Persistent depre ssivesymptoms lower aspirin adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Kronish IM, Rieckmann N, Halm EA, and others find about adherence to secondary prevention behaviors after acute coronary syndromes?. ### Response: Persistent depressionaffects adherence to secondary prevention behaviors after acutecoronary syndromes. J Gen Intern Med. 2006;21:1178–83.689. McKellar JD, Humphreys K, Piette JD. Depression increases diabetessymptoms by complicating patients’ self-care adherence. D iabetesEduc. 2004;30:485–92.690. Rieckmann N, Kronish IM, Haas D, et al. Persistent depre ssivesymptoms lower aspirin adherence.


Instruction: What causes diabetessymptoms to increase?

Output: Depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes diabetessymptoms to increase?. ### Response: Depression.


Instruction: What causes patients to have difficulty with self-care adherence?

Output: Depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes patients to have difficulty with self-care adherence?. ### Response: Depression.


Instruction: When was the last year of the J Gen Intern Med?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last year of the J Gen Intern Med?. ### Response: 2006.


Instruction: What is the name of the study that examined the course of depressivesymptoms and medication adherence after acute coronary syndromes?

Output: Heart andSoul Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the course of depressivesymptoms and medication adherence after acute coronary syndromes?. ### Response: Heart andSoul Study.


Instruction: What are the names of the authors of the electronic medication monitoring study?

Output: Laghrissi-Thode F, Wagner WR, Pollock BG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the electronic medication monitoring study?. ### Response: Laghrissi-Thode F, Wagner WR, Pollock BG.


Instruction: What is the name of the study that evaluated plateletactivation in depressed patients with ischemic heart disease?

Output: Pollock BG, Laghrissi-Thode F, Wagner WR. Evaluation of plateletactivation in depressed patients with ischemic heart disease after par-oxetine or nortriptyline treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated plateletactivation in depressed patients with ischemic heart disease?. ### Response: Pollock BG, Laghrissi-Thode F, Wagner WR. Evaluation of plateletactivation in depressed patients with ischemic heart disease after par-oxetine or nortriptyline treatment.


Instruction: What are the names of the studies that examined plateletfactor 4 and beta-thromboglobulin plasma levels?

Output: Laghrissi-Thode F, Wagner WR, Pollock BG, et al. Elevated plateletfactor 4 and beta-thromboglobulin plasma levels in depressed patientswith ischemic heart disease. Biol Psychiatry. 1997;42:290–5.693. Mussel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the studies that examined plateletfactor 4 and beta-thromboglobulin plasma levels?. ### Response: Laghrissi-Thode F, Wagner WR, Pollock BG, et al. Elevated plateletfactor 4 and beta-thromboglobulin plasma levels in depressed patientswith ischemic heart disease. Biol Psychiatry. 1997;42:290–5.693. Mussel.


Instruction: In what year did Biol Psychiatry publish?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Biol Psychiatry publish?. ### Response: 1997.


Instruction: What is a possible link between depression and acute coronarysyndromes?

Output: Exaggerated serotoninmediatedplatelet reactivity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible link between depression and acute coronarysyndromes?. ### Response: Exaggerated serotoninmediatedplatelet reactivity.


Instruction: What is the effect of par-oxetine and nortriptyline on plateletactivation?

Output: Evaluation of plateletactivation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of par-oxetine and nortriptyline on plateletactivation?. ### Response: Evaluation of plateletactivation.


Instruction: What year did J Cardiol. 2002:89:331–3.696?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Cardiol. 2002:89:331–3.696?. ### Response: 2005.


Instruction: What is the effect of majordepression on heart rate variability?

Output: Clinical consequences and impli-cations for antidepressive treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of majordepression on heart rate variability?. ### Response: Clinical consequences and impli-cations for antidepressive treatment.


Instruction: When was the last time a patient with depressive symptom-atology had a heart attack?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a patient with depressive symptom-atology had a heart attack?. ### Response: 1997.


Instruction: What are the consequences of antidepressive treatment?

Output: Clinical consequences and impli-cations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the consequences of antidepressive treatment?. ### Response: Clinical consequences and impli-cations.


Instruction: What is the effect of heart ratevariability on acute myocardial infarction?

Output: Depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of heart ratevariability on acute myocardial infarction?. ### Response: Depression.


Instruction: What is the name of the journal that published in 2000?

Output: J Clin Psychopharmacol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published in 2000?. ### Response: J Clin Psychopharmacol.


Instruction: What are the names of the authors of the study?

Output: Pollock BG, Laghrissi-Thode F, Wagner WR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the study?. ### Response: Pollock BG, Laghrissi-Thode F, Wagner WR.


Instruction: What does Kelkar PS, Li JT say about cephalosporin allergy?

Output: 2001;345:804–809.96

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Kelkar PS, Li JT say about cephalosporin allergy?. ### Response: 2001;345:804–809.96.


Instruction: What does GuayDR, PattersonDR, Seipman N, Craft JC say about clarithromycin in preclinical and clinical trials?

Output: toler-ability profile

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GuayDR, PattersonDR, Seipman N, Craft JC say about clarithromycin in preclinical and clinical trials?. ### Response: toler-ability profile.


Instruction: How does Clindamycin hypersensitivity appear?

Output: rare

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Clindamycin hypersensitivity appear?. ### Response: rare.


Instruction: What does Clindamycin hypersensitivity appears to be?

Output: rare

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Clindamycin hypersensitivity appears to be?. ### Response: rare.


Instruction: What is Clostridium difficile colitisfollowing antibiotic prophylaxis for dental procedures?

Output: Wetmore SJ, John MA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Clostridium difficile colitisfollowing antibiotic prophylaxis for dental procedures?. ### Response: Wetmore SJ, John MA.


Instruction: Infective endocarditis: a population-basedstudy in what county, Minnesota?

Output: Olmsted County

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis: a population-basedstudy in what county, Minnesota?. ### Response: Olmsted County.


Instruction: What is the name of the county in which the study was conducted?

Output: Olmsted County

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the county in which the study was conducted?. ### Response: Olmsted County.


Instruction: How long was the study in Olmsted County, Minnesota, from 1950 to 1981?

Output: 1950 through 1981

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the study in Olmsted County, Minnesota, from 1950 to 1981?. ### Response: 1950 through 1981.


Instruction: What is the name of the American Heart Association symposium held May 14-15, 1976?

Output: Infective Endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the American Heart Association symposium held May 14-15, 1976?. ### Response: Infective Endocarditis.


Instruction: When was the AHA Monograph #52 published?

Output: 1977

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the AHA Monograph #52 published?. ### Response: 1977.


Instruction: How long was the survey conducted on infective endocarditis in France?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the survey conducted on infective endocarditis in France?. ### Response: 1-year.


Instruction: In what year did a 1-year survey of infective endo-carditis occur in France?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did a 1-year survey of infective endo-carditis occur in France?. ### Response: 1991.


Instruction: What is the name of the study conducted in 1991?

Output: Association pour l’Etude et laPrevention de l’Endocardite Infectieuse (AEPEI) Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study conducted in 1991?. ### Response: Association pour l’Etude et laPrevention de l’Endocardite Infectieuse (AEPEI) Study Group.


Instruction: How long did the survey last?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the survey last?. ### Response: 1-year.


Instruction: What is AEPEI?

Output: vention de l’Endocardite Infectieuse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AEPEI?. ### Response: vention de l’Endocardite Infectieuse.


Instruction: What is the name of the study group that studied infective endocarditis?

Output: Association pour l’Etude et laPrevention de l’Endocardite Infectieuse (AEPEI) Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studied infective endocarditis?. ### Response: Association pour l’Etude et laPrevention de l’Endocardite Infectieuse (AEPEI) Study Group.