Instruction: How should a new event be treated?

Output: willdepend on the reason(s) for recurrence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should a new event be treated?. ### Response: willdepend on the reason(s) for recurrence.


Instruction: What is CKD?

Output: chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD?. ### Response: chronic kidney disease.


Instruction: What is the glomerular filtration rate?

Output: GFR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the glomerular filtration rate?. ### Response: GFR.


Instruction: What is GFR?

Output: glomerular filtration rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GFR?. ### Response: glomerular filtration rate.


Instruction: What does CKD 1-5T notation apply to?

Output: kidney transplant recipients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CKD 1-5T notation apply to?. ### Response: kidney transplant recipients.


Instruction: If dialysis (HD or PD) is used, what is the 5D?

Output: a5D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If dialysis (HD or PD) is used, what is the 5D?. ### Response: a5D.


Instruction: • reduce antihyper tensiv e treatment if t heir blood pr essur e falls belo w 130/80 mmHg?

Output: yper

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: • reduce antihyper tensiv e treatment if t heir blood pr essur e falls belo w 130/80 mmHg?. ### Response: yper.


Instruction: 1.18 If a w oman has tak en met hyldopa to treat what?

Output: pr e-eclampsia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1.18 If a w oman has tak en met hyldopa to treat what?. ### Response: pr e-eclampsia.


Instruction: How many days aft er the bir th and change t o an alt ernativ e treatment if necessar y?

Output: 2 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days aft er the bir th and change t o an alt ernativ e treatment if necessar y?. ### Response: 2 days.


Instruction: See section 1.9 for choice of what during the postnatal period?

Output: antih yper tensiv e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: See section 1.9 for choice of what during the postnatal period?. ### Response: antih yper tensiv e.


Instruction: What do women with pre-eclampsia who have giv en bir th transf er get if all of the following criteria ha ve been met?

Output: community car e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do women with pre-eclampsia who have giv en bir th transf er get if all of the following criteria ha ve been met?. ### Response: community car e.


Instruction: What is the blood pressure of women with e-eclampsia?

Output: 150/100  mmHg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the blood pressure of women with e-eclampsia?. ### Response: 150/100  mmHg.


Instruction: How is blood pressure measured?

Output: 150/100  mmHg or less

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is blood pressure measured?. ### Response: 150/100  mmHg or less.


Instruction: What are the results of blood tests?

Output: stable or impr oving

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of blood tests?. ### Response: stable or impr oving.


Instruction: Pre-eclampsia women who have giv en bir th and ar e being transf erred to a community car include all of the following: • who will pr ovide f ollow-up car e, including medical r eview if needed?

Output: GP or specialist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pre-eclampsia women who have giv en bir th and ar e being transf erred to a community car include all of the following: • who will pr ovide f ollow-up car e, including medical r eview if needed?. ### Response: GP or specialist.


Instruction: What is the frequency of blood pr essur e monitoring?

Output: 130/80 mmHg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the frequency of blood pr essur e monitoring?. ### Response: 130/80 mmHg.


Instruction: What are indications for f or referral t o primar y car e for?

Output: blood pr essur e review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are indications for f or referral t o primar y car e for?. ### Response: blood pr essur e review.


Instruction: What do women who have had pr e-eclampsia and r emain on antih yper tensiv e treatment need to do?

Output: Write a car e plan f

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do women who have had pr e-eclampsia and r emain on antih yper tensiv e treatment need to do?. ### Response: Write a car e plan f.


Instruction: How long aft er transf er to a community car e?

Output: 2 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long aft er transf er to a community car e?. ### Response: 2 weeks.


Instruction: What is aft er transf er to community car e?

Output: 2 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aft er transf er to community car e?. ### Response: 2 weeks.


Instruction: What is an offer to all women who have had pr e-eclampsia a medical r eview wit h their GP or specialist?

Output: 6–8  weeks aft er the bir th

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an offer to all women who have had pr e-eclampsia a medical r eview wit h their GP or specialist?. ### Response: 6–8  weeks aft er the bir th.


Instruction: What is the name of the book that describes the treatment of pre-eclampsia in women with mild or moderat e hyper tension?

Output: Hyper tension in pr egnancy: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes the treatment of pre-eclampsia in women with mild or moderat e hyper tension?. ### Response: Hyper tension in pr egnancy: diagnosis and management.


Instruction: When was the book NG133 published?

Output: NICE 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the book NG133 published?. ### Response: NICE 2023.


Instruction: What is the subject of Notice of right s?

Output: All right s reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the subject of Notice of right s?. ### Response: All right s reserved.


Instruction: When was the last updat ed?

Output: 17 April 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed?. ### Response: 17 April 2023.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 117 of 127 sedentary behavior?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 117 of 127 sedentary behavior?. ### Response: ”.


Instruction: A provider's considerations when recommending physical activity might include a patient's motivation, functional capacity, and what else?

Output: physical activity preferences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A provider's considerations when recommending physical activity might include a patient's motivation, functional capacity, and what else?. ### Response: physical activity preferences.


Instruction: What box connects to Box 13?

Output: Box 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What box connects to Box 13?. ### Response: Box 12.


Instruction: What is the shape of Box 12?

Output: a rectangle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the shape of Box 12?. ### Response: a rectangle.


Instruction: How many years does it take to stop smoking?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years does it take to stop smoking?. ### Response: 5.


Instruction: How many years should a person take lipids every 2 years if they are 6 – 12%?

Output: 10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years should a person take lipids every 2 years if they are 6 – 12%?. ### Response: 10 years.


Instruction: How often should you take a lipid as needed only if you are at a higher risk and willing to intensify?

Output: every 10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often should you take a lipid as needed only if you are at a higher risk and willing to intensify?. ### Response: every 10 years.


Instruction: Once on optimal therapy, no need to recheck what?

Output: lipids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Once on optimal therapy, no need to recheck what?. ### Response: lipids.


Instruction: What is ventricular systolic dysfunction?

Output: Revascularization inpatients with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ventricular systolic dysfunction?. ### Response: Revascularization inpatients with heart failure.


Instruction: What is the name of the journal that describes revascularization inpatients with heart failure?

Output: CMAJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that describes revascularization inpatients with heart failure?. ### Response: CMAJ.


Instruction: How long did Coronary bypass surgery last?

Output: 15-yearperiod

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did Coronary bypass surgery last?. ### Response: 15-yearperiod.


Instruction: What is the effect of the internal-mammary-artery graft on survival?

Output: 10-year survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of the internal-mammary-artery graft on survival?. ### Response: 10-year survival.


Instruction: How long does it take for patients with multivessel coronary artery disease to survive after a revascularization?

Output: one- to eight-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for patients with multivessel coronary artery disease to survive after a revascularization?. ### Response: one- to eight-year.


Instruction: When was the N Engl J Med 314:1–6.71 published?

Output: 1986

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 314:1–6.71 published?. ### Response: 1986.


Instruction: What type of revascularization is recommended in patients with multivessel coronary artery disease and high-risk features?

Output: percutaneous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of revascularization is recommended in patients with multivessel coronary artery disease and high-risk features?. ### Response: percutaneous.


Instruction: What is the effect of diabetes on 5-year mortality and morbidity in a randomized trial?

Output: Influence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of diabetes on 5-year mortality and morbidity in a randomized trial?. ### Response: Influence.


Instruction: What is the name of the randomized trial comparing CABG and PTCA in patients with multivessel disease?

Output: Bypass Angioplasty RevascularizationInvestigation (BARI).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial comparing CABG and PTCA in patients with multivessel disease?. ### Response: Bypass Angioplasty RevascularizationInvestigation (BARI)..


Instruction: How long did the BARI trial last?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the BARI trial last?. ### Response: 10-year.


Instruction: What was the final 10-year follow-up results from theBARI trial?

Output: The BARI Investigators. The final 10-year follow-up results from theBARI randomized trial. J Am Coll Cardiol. 2007;49:1600–6.76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the final 10-year follow-up results from theBARI trial?. ### Response: The BARI Investigators. The final 10-year follow-up results from theBARI randomized trial. J Am Coll Cardiol. 2007;49:1600–6.76.


Instruction: When was the J Am Coll Cardiol 49:1600–6.76?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 49:1600–6.76?. ### Response: 2007.


Instruction: What is the name of the study that compares cardiac surgery and paclitaxel-eluting stents?

Output: The BARI Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares cardiac surgery and paclitaxel-eluting stents?. ### Response: The BARI Investigators.


Instruction: What is a meta-analysis of ran-domized controlled trials?

Output: one- to eight-yearoutcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of ran-domized controlled trials?. ### Response: one- to eight-yearoutcomes.


Instruction: What is the name of the meta-analysis that compares coronary artery bypass graft withpercutaneous transluminal coronary angioplasty?

Output: A meta-analysis of ran-domized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis that compares coronary artery bypass graft withpercutaneous transluminal coronary angioplasty?. ### Response: A meta-analysis of ran-domized controlled trials.


Instruction: How long does the follow-up of theMASS II study last?

Output: Five-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does the follow-up of theMASS II study last?. ### Response: Five-year.


Instruction: What is the name of the randomizedcontrolled clinical trial of 3 therapeutic strategies for multivesselcoronary artery disease?

Output: Medicine, Angioplasty, or Surgery Study (MASS II):

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomizedcontrolled clinical trial of 3 therapeutic strategies for multivesselcoronary artery disease?. ### Response: Medicine, Angioplasty, or Surgery Study (MASS II):.


Instruction: When was the Surgery Study conducted?

Output: Five-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Surgery Study conducted?. ### Response: Five-year.


Instruction: How many therapeutic strategies were used in the surgery study?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many therapeutic strategies were used in the surgery study?. ### Response: 3.


Instruction: What was the outcome of the surgical study in 2007?

Output: 49:1600–6.76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the surgical study in 2007?. ### Response: 49:1600–6.76.


Instruction: What is the name of the study group that studies the survival of patients with diabetes and multivessel coronary artery disease after surgical or percutaneouscoronary revascularization?

Output: Northern New EnglandCardiovascular Disease Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studies the survival of patients with diabetes and multivessel coronary artery disease after surgical or percutaneouscoronary revascularization?. ### Response: Northern New EnglandCardiovascular Disease Study Group.


Instruction: What year was Circu-lation published?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Circu-lation published?. ### Response: 2005.


Instruction: What is the name of the prospective study in 2001?

Output: Northern New EnglandCardiovascular Disease Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study in 2001?. ### Response: Northern New EnglandCardiovascular Disease Study Group.


Instruction: What was the outcome of coronary bypasssurgery versus coronary angioplasty in diabetic patients with multivesselcoronary artery disease?

Output: one- to eight-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of coronary bypasssurgery versus coronary angioplasty in diabetic patients with multivesselcoronary artery disease?. ### Response: one- to eight-year.


Instruction: What is the name of the study?

Output: Medicine, Angioplasty, or Surgery Study (MASS II):

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: Medicine, Angioplasty, or Surgery Study (MASS II):.


Instruction: What type of therapy is best for stable coronary disease?

Output: Optimal medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is best for stable coronary disease?. ### Response: Optimal medical therapy.


Instruction: What is expected.B-NRIIa B-NR2?

Output: stable VT is likely a marker for a substrate capable of producing subsequent lethal arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is expected.B-NRIIa B-NR2?. ### Response: stable VT is likely a marker for a substrate capable of producing subsequent lethal arrhythmias.


Instruction: What can be beneficial in patients with NICM who experience syncope presumed to be due to VA and do not meet indications for a primary prevention ICD?

Output: an ICD or an electrophysiological study for risk stratification for SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial in patients with NICM who experience syncope presumed to be due to VA and do not meet indications for a primary prevention ICD?. ### Response: an ICD or an electrophysiological study for risk stratification for SCD.


Instruction: What is beneficial if meaningful survival greater than 1 year is expected?

Output: an ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial if meaningful survival greater than 1 year is expected?. ### Response: an ICD.


Instruction: In patients with NICM who survive a cardiac arrest, have sustained VT, or have symptomatic VA who are ineligible for an ICD, what is amiodarone?

Output: prevention of SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with NICM who survive a cardiac arrest, have sustained VT, or have symptomatic VA who are ineligible for an ICD, what is amiodarone?. ### Response: prevention of SCD.


Instruction: What may be considered for prevention of SCD?

Output: amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for prevention of SCD?. ### Response: amiodarone.


Instruction: How many prospective RCTs compared the ICD with pharmacological therapy in patients resuscitated from SCA due to VT/VF or hemodynamically sig-nificant VT?

Output: Three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prospective RCTs compared the ICD with pharmacological therapy in patients resuscitated from SCA due to VT/VF or hemodynamically sig-nificant VT?. ### Response: Three.


Instruction: What were the most common antiarrhythmic medications?

Output: amio-darone, a beta blocker, or both

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the most common antiarrhythmic medications?. ### Response: amio-darone, a beta blocker, or both.


Instruction: What was the name of the CASH trial?

Output: Cardiac Arrest Study Hamburg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the CASH trial?. ### Response: Cardiac Arrest Study Hamburg.


Instruction: Why was a propafenone arm termi-nated early?

Output: increased mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was a propafenone arm termi-nated early?. ### Response: increased mortality.


Instruction: How many patients had NICM?

Output: 292

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had NICM?. ### Response: 292.


Instruction: How many patients had NICM in 1963?

Output: 292

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had NICM in 1963?. ### Response: 292.


Instruction: How much reduction in all-cause mortality did AVID and CIDS find?

Output: 31%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much reduction in all-cause mortality did AVID and CIDS find?. ### Response: 31%.


Instruction: What was consistent with the observed benefit in the entire study popula-tion?

Output: the observed mortality reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was consistent with the observed benefit in the entire study popula-tion?. ### Response: the observed mortality reduction.


Instruction: What was associated with a mortality rate similar to that of S7.2.1-1 patients?

Output: sustained VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a mortality rate similar to that of S7.2.1-1 patients?. ### Response: sustained VT.


Instruction: What was associated with a mortality rate similar to that of patients with unstable VT?

Output: sustained VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a mortality rate similar to that of patients with unstable VT?. ### Response: sustained VT.


Instruction: What is likely a marker for a substrate capable of producing subsequent lethal arrhythmias?

Output: stable VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely a marker for a substrate capable of producing subsequent lethal arrhythmias?. ### Response: stable VT.


Instruction: What is the name of the meta-analysis that compares the efficacy and acceptability of antidepressant treatment in poststroke depression?

Output: multiple-treatments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis that compares the efficacy and acceptability of antidepressant treatment in poststroke depression?. ### Response: multiple-treatments.


Instruction: How many treatments did BMJ Open present in 2017?

Output: 482

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many treatments did BMJ Open present in 2017?. ### Response: 482.


Instruction: How many randomized controlled trials were included in the meta-analysis of interventions for management of post-stroke depression?

Output: 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized controlled trials were included in the meta-analysis of interventions for management of post-stroke depression?. ### Response: 23.


Instruction: What is the name of the study that analyzed the 23 trials?

Output: bayesian network

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that analyzed the 23 trials?. ### Response: bayesian network.


Instruction: What did Liu M, Cheng Y, Jia C, Pan X, Gou Q, Liu X and Zhang L use for the treatment of post stroke depression?

Output: Repetitive transcranial magnetic stimulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Liu M, Cheng Y, Jia C, Pan X, Gou Q, Liu X and Zhang L use for the treatment of post stroke depression?. ### Response: Repetitive transcranial magnetic stimulation.


Instruction: What is the name of the systematic review and meta-analysis of random-ized controlled clinical trials?

Output: Repetitive transcranial magnetic stimulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis of random-ized controlled clinical trials?. ### Response: Repetitive transcranial magnetic stimulation.


Instruction: What is the name of the journal that studies the effectiveness of antidepressant treatment in patients with post-stroke depression?

Output: BMJ Open

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the effectiveness of antidepressant treatment in patients with post-stroke depression?. ### Response: BMJ Open.


Instruction: When was this journal published?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this journal published?. ### Response: 2017.


Instruction: Where can this journal be found?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can this journal be found?. ### Response: http://ahajournals.org.


Instruction: What is the rate of SIHD compared with persistent ischemia?

Output: 92%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rate of SIHD compared with persistent ischemia?. ### Response: 92%).


Instruction: What is a part of the ongoing technical evolution withinimaging modalities?

Output: minimizing intraob-server, interobserver, and intertest variability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a part of the ongoing technical evolution withinimaging modalities?. ### Response: minimizing intraob-server, interobserver, and intertest variability.


Instruction: What is the potential to improve the diagnosis of IHD and to assess risk according to clinical information and results from noninvasive testing?

Output: Large registries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the potential to improve the diagnosis of IHD and to assess risk according to clinical information and results from noninvasive testing?. ### Response: Large registries.


Instruction: What should be updated with modern information and statistical techniques?

Output: Risk-assessment strategies from older databases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be updated with modern information and statistical techniques?. ### Response: Risk-assessment strategies from older databases.


Instruction: What is one of the goals of CT scanners and software?

Output: improve the spatial and temporalresolution of cardiac CT images while reducing the radiationdose received from a typical examination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the goals of CT scanners and software?. ### Response: improve the spatial and temporalresolution of cardiac CT images while reducing the radiationdose received from a typical examination.


Instruction: What is another goal of CT scans andsoftware?

Output: improve the spatial and temporalresolution of cardiac CT images while reducing the radiationdose received from a typical examination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another goal of CT scans andsoftware?. ### Response: improve the spatial and temporalresolution of cardiac CT images while reducing the radiationdose received from a typical examination.


Instruction: How does the radiation dose from a typical examination compare to a CT scan?

Output: reducing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the radiation dose from a typical examination compare to a CT scan?. ### Response: reducing.


Instruction: What could improve the diagnostic value of CCTA in currently challenging scenarios?

Output: alternative image reconstruction techniques that targetimage noise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could improve the diagnostic value of CCTA in currently challenging scenarios?. ### Response: alternative image reconstruction techniques that targetimage noise.


Instruction: What could be improved by using widerdetector arrays?

Output: higher numbers of simultaneouslyacquired image slices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be improved by using widerdetector arrays?. ### Response: higher numbers of simultaneouslyacquired image slices.


Instruction: What are calcifiedcoronary arteries and coronary stents?

Output: currently challenging scenarios

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are calcifiedcoronary arteries and coronary stents?. ### Response: currently challenging scenarios.


Instruction: What are newer applications ofcardiac CT?

Output: coronary plaque characterization, lateenhancement imaging for the detection of myocardial scar,and MPI to detect myocardial ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are newer applications ofcardiac CT?. ### Response: coronary plaque characterization, lateenhancement imaging for the detection of myocardial scar,and MPI to detect myocardial ischemia.


Instruction: MPI is used to detect what?

Output: myocardial ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: MPI is used to detect what?. ### Response: myocardial ischemia.


Instruction: What is in development and could further guide accuratedetection of atherosclerotic disease burden?

Output: plaque quantification soft-ware

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is in development and could further guide accuratedetection of atherosclerotic disease burden?. ### Response: plaque quantification soft-ware.


Instruction: What new developments have occurred in stress nuclear MPI?

Output: new radioisotopes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What new developments have occurred in stress nuclear MPI?. ### Response: new radioisotopes.


Instruction: What will allow exercise PETtesting?

Output: F18 PET perfu-sion agent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will allow exercise PETtesting?. ### Response: F18 PET perfu-sion agent.


Instruction: What is the unique ability of 123I-beta-methyl-iodophenylpentadecanoic acidSPECT?

Output: to document metabolicalterations representing prior ischemic episodes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the unique ability of 123I-beta-methyl-iodophenylpentadecanoic acidSPECT?. ### Response: to document metabolicalterations representing prior ischemic episodes.


Instruction: What is the risk of arrhythmicrisk in SIHD patients?

Output: 92%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of arrhythmicrisk in SIHD patients?. ### Response: 92%).


Instruction: What has been introduced into the marketplace and offer theopportunity for improved image quality?

Output: SPECT cameras

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been introduced into the marketplace and offer theopportunity for improved image quality?. ### Response: SPECT cameras.


Instruction: What is currently under intenseinvestigation?

Output: PET flow reserve data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is currently under intenseinvestigation?. ### Response: PET flow reserve data.


Instruction: What is the most portable and widely available stress imaging technique?

Output: Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most portable and widely available stress imaging technique?. ### Response: Echocardiography.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the DOI: 10.1161/CIR.0000000000000923 February 2, 2021 e145CLINICAL STATEMENTS AND GUIDELINESstudy showed that patients who received anticoagulation had a lower rate of what?

Output: thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI: 10.1161/CIR.0000000000000923 February 2, 2021 e145CLINICAL STATEMENTS AND GUIDELINESstudy showed that patients who received anticoagulation had a lower rate of what?. ### Response: thromboembolism.


Instruction: What was the incidence of ischemic stroke within the first 30 postoperative days?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the incidence of ischemic stroke within the first 30 postoperative days?. ### Response: higher.


Instruction: What was higher after replacement with a biological pros-thesis than after mitral valve repair?

Output: chemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was higher after replacement with a biological pros-thesis than after mitral valve repair?. ### Response: chemic stroke.


Instruction: What percentage of mitral valve repair does a mechanical prosthesis replace?

Output: 1.5%±0.4%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of mitral valve repair does a mechanical prosthesis replace?. ### Response: 1.5%±0.4%).


Instruction: What has not established a convincing net benefit of anticoagulation after implantation of a bioprosthetic AVR24?

Output: Small studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not established a convincing net benefit of anticoagulation after implantation of a bioprosthetic AVR24?. ### Response: Small studies.


Instruction: A large obser -vational Danish registry demonstrated a lower risk of stroke and death with what type of valve?

Output: VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A large obser -vational Danish registry demonstrated a lower risk of stroke and death with what type of valve?. ### Response: VKA.


Instruction: How long did VKA last?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did VKA last?. ### Response: 6 months.


Instruction: What has been raised about the incidence of subclinical bioprosthetic valve leaflet thrombosis?

Output: Concern

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been raised about the incidence of subclinical bioprosthetic valve leaflet thrombosis?. ### Response: Concern.


Instruction: What percentage of anticoagulated patients in the registry were discharged on warfarin?

Output: Ninety-five percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of anticoagulated patients in the registry were discharged on warfarin?. ### Response: Ninety-five percent.


Instruction: What type of AVR was used after bioprosthetic?

Output: anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of AVR was used after bioprosthetic?. ### Response: anticoagulation.


Instruction: What did the registry discharged on?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the registry discharged on?. ### Response: warfarin.


Instruction: What was the prior recommendation to add low-dose aspi-rin to therapeutic VKA therapy for a mechanical valve prosthesis based on studies performed decades ago?

Output: 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the prior recommendation to add low-dose aspi-rin to therapeutic VKA therapy for a mechanical valve prosthesis based on studies performed decades ago?. ### Response: 8.


Instruction: What did a 2013 Cochrane Systematic Review show about the addition of an antiplatelet agent?

Output: reduced the risk of thromboembolic events and the total mortality rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a 2013 Cochrane Systematic Review show about the addition of an antiplatelet agent?. ### Response: reduced the risk of thromboembolic events and the total mortality rate.


Instruction: What did the authors note about the quality of the included tri-als?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the authors note about the quality of the included tri-als?. ### Response: low.


Instruction: What was the era when most trials were conducted?

Output: decades ago

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the era when most trials were conducted?. ### Response: decades ago.


Instruction: An individual-alized approach that takes the risk of bleeding into account is what?

Output: individu

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: An individual-alized approach that takes the risk of bleeding into account is what?. ### Response: individu.


Instruction: What is required in patients without risk factors who receive a mechanical On-X aortic heart valve?

Output: An individu-alized approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required in patients without risk factors who receive a mechanical On-X aortic heart valve?. ### Response: An individu-alized approach.


Instruction: What may be a strategy for long-term?

Output: targeting the INR to a lower goal (1.5–2.0) in conjunction with aspirin 81 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be a strategy for long-term?. ### Response: targeting the INR to a lower goal (1.5–2.0) in conjunction with aspirin 81 mg daily.


Instruction: Aspirin 81 mg daily may be a strategy for what?

Output: long-term management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin 81 mg daily may be a strategy for what?. ### Response: long-term management.


Instruction: What is tar -geted to an INR of 2.5 for the first 3 months after surgery?

Output: Warfarin dosing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tar -geted to an INR of 2.5 for the first 3 months after surgery?. ### Response: Warfarin dosing.


Instruction: Low-dose aspirin is also used during what time period?

Output: first 3 months after surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Low-dose aspirin is also used during what time period?. ### Response: first 3 months after surgery.


Instruction: What did the lower-intensity INR group experience signifi-cally?

Output: quality of the included tri-als tended to be low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the lower-intensity INR group experience signifi-cally?. ### Response: quality of the included tri-als tended to be low.


Instruction: What was used in a single RCT27?

Output: low-dose aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used in a single RCT27?. ### Response: low-dose aspirin.


Instruction: What should adults be categorized as 10% or >10% 10-year ASCVD risk for therapeutic decisions?

Output: 20 to 39 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should adults be categorized as 10% or >10% 10-year ASCVD risk for therapeutic decisions?. ### Response: 20 to 39 years of age.


Instruction: For management of blood cholesterol, adults should be categorised as having low (5%), borderline (5% to 7.5%), intermediate (5%to 20%) or what?

Output: intermedi-ate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For management of blood cholesterol, adults should be categorised as having low (5%), borderline (5% to 7.5%), intermediate (5%to 20%) or what?. ### Response: intermedi-ate.


Instruction: What are best validated?

Output: The PCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are best validated?. ### Response: The PCE.


Instruction: What is the risk of PCE overestimating or underestimating?

Output: In other racial/ethnic groupsS2.2-53,S2.2-54 or in some non-US populations,S2.2-40,S2.2-41,S2.2-53,S2.2-54

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of PCE overestimating or underestimating?. ### Response: In other racial/ethnic groupsS2.2-53,S2.2-54 or in some non-US populations,S2.2-40,S2.2-41,S2.2-53,S2.2-54.


Instruction: What may clinicians consider the use of as an alternative to the PCE?

Output: another risk prediction tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may clinicians consider the use of as an alternative to the PCE?. ### Response: another risk prediction tool.


Instruction: What is SCORE?

Output: Systematic COronary Risk Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SCORE?. ### Response: Systematic COronary Risk Evaluation.


Instruction: What is the general Framingham CVD risk score?

Output: S2.2-55

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the general Framingham CVD risk score?. ### Response: S2.2-55.


Instruction: What does SCORE stand for?

Output: Systematic COronary Risk Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SCORE stand for?. ### Response: Systematic COronary Risk Evaluation.


Instruction: What is the acronym for Systematic COronary Risk Evaluation?

Output: SCORE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Systematic COronary Risk Evaluation?. ### Response: SCORE.


Instruction: Other professional societies have incorporated some of these risk scores into what?

Output: lipid manage-ment guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Other professional societies have incorporated some of these risk scores into what?. ### Response: lipid manage-ment guidelines.


Instruction: What is the goal of the organi-zational guidelines?

Output: matching the intensity of preventive therapies to the absolute (generally 10-year) risk of the patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of the organi-zational guidelines?. ### Response: matching the intensity of preventive therapies to the absolute (generally 10-year) risk of the patient.


Instruction: What are the goals of the Organi-zonal Guidelines?

Output: matching the intensity of preventive therapies to the absolute (generally 10-year) risk of the patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the goals of the Organi-zonal Guidelines?. ### Response: matching the intensity of preventive therapies to the absolute (generally 10-year) risk of the patient.


Instruction: After what age is it reasonable to measure traditional risk factors every 4 to 6 years?

Output: 20 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After what age is it reasonable to measure traditional risk factors every 4 to 6 years?. ### Response: 20 years.


Instruction: How often are risk factors at least every 4 to 6 years?

Output: After age 20 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often are risk factors at least every 4 to 6 years?. ### Response: After age 20 years.


Instruction: For adults 20 to 39 years of age, how much data exists on the performance and utility of 10-year risk estimation tools?

Output: limited

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For adults 20 to 39 years of age, how much data exists on the performance and utility of 10-year risk estimation tools?. ### Response: limited.


Instruction: What is a major driver of risk?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major driver of risk?. ### Response: age.


Instruction: What age range is unlikely to have a sufficiently elevated 10-year risk to warrant pharmacological therapy with a statin?

Output: (<40 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What age range is unlikely to have a sufficiently elevated 10-year risk to warrant pharmacological therapy with a statin?. ### Response: (<40 years.


Instruction: What is peri-odic assessment of risk factors in younger adults 20 to 39 years?

Output: at least every 4 to 6 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is peri-odic assessment of risk factors in younger adults 20 to 39 years?. ### Response: at least every 4 to 6 years.


Instruction: What is important to guide discussions about inten-sity of lifestyle interventions?

Output: peri-odic assessment of risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to guide discussions about inten-sity of lifestyle interventions?. ### Response: peri-odic assessment of risk factors.


Instruction: What is considered consideration of 30-year or lifetime risk estimation?

Output: peri-odic assessment of risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered consideration of 30-year or lifetime risk estimation?. ### Response: peri-odic assessment of risk factors.


Instruction: No single risk calculator is appropriate for all patients?

Output: S2.2-1–S2.2-33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No single risk calculator is appropriate for all patients?. ### Response: S2.2-1–S2.2-33.


Instruction: No single risk calculator is appropriate for all patients.

Output: S2.2-1–S2.2-33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No single risk calculator is appropriate for all patients.. ### Response: S2.2-1–S2.2-33.


Instruction: What does the PCE have reasonable calibration for?

Output: In certain populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the PCE have reasonable calibration for?. ### Response: In certain populations.


Instruction: Some studies have found underestimation of risk among indi-viduals with chronic inflammatory conditions?

Output: socioeconomic disadvantage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some studies have found underestimation of risk among indi-viduals with chronic inflammatory conditions?. ### Response: socioeconomic disadvantage.


Instruction: InfectionS2.2-12) or socioeconomic disadvantageS2.2-48, S2.2-49, and S2.2-21 What are the Recommendations for Assessment of Cardiovascular Risk?

Output: COR LOE Recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: InfectionS2.2-12) or socioeconomic disadvantageS2.2-48, S2.2-49, and S2.2-21 What are the Recommendations for Assessment of Cardiovascular Risk?. ### Response: COR LOE Recommendations.


Instruction: What do Japanese patients may be sensitive to statin dosing?

Output: Intensity of statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do Japanese patients may be sensitive to statin dosing?. ### Response: Intensity of statin therapy.


Instruction: What did Japanese participants have a reduction in with low-intensity doses of pravastatin?

Output: CVD events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Japanese participants have a reduction in with low-intensity doses of pravastatin?. ### Response: CVD events.


Instruction: What did CVD events with low-intensity doses of pravastatin as compared with placebo?

Output: reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did CVD events with low-intensity doses of pravastatin as compared with placebo?. ### Response: reduction.


Instruction: What did Japanese participants with CAD benefit from a secondary-prevention trial?

Output: moderate-intensity dose of pitavastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Japanese participants with CAD benefit from a secondary-prevention trial?. ### Response: moderate-intensity dose of pitavastatin.


Instruction: No sensitivity to statin dosage is seen in non-Hispanic white or black individuals?

Output: There are no specific safety issues with statins related to Hispanic/Latino ethnicity.S4.5.1-38Baseline serum CK values are higher in blacks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No sensitivity to statin dosage is seen in non-Hispanic white or black individuals?. ### Response: There are no specific safety issues with statins related to Hispanic/Latino ethnicity.S4.5.1-38Baseline serum CK values are higher in blacks.


Instruction: What is seen in Japanese, Chinese, Malay, and Asian Indians?

Output: Higher rosuvastatin plasma levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is seen in Japanese, Chinese, Malay, and Asian Indians?. ### Response: Higher rosuvastatin plasma levels.


Instruction: What may give results similar to those seen with higher statin intensity in non-Japanese patients?

Output: Using a lower statin intensity in Japanese patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may give results similar to those seen with higher statin intensity in non-Japanese patients?. ### Response: Using a lower statin intensity in Japanese patients.


Instruction: What is the starting dose of rosuvastatin in Asians compared to?

Output: 5 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the starting dose of rosuvastatin in Asians compared to?. ### Response: 5 mg.


Instruction: What ethnicity are there no specific safety issues with statins?

Output: Hispanic/Latino

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What ethnicity are there no specific safety issues with statins?. ### Response: Hispanic/Latino.


Instruction: What ethnicity is associated with safety issues with statins?

Output: Japanese, Chinese, Malay, and Asian Indians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What ethnicity is associated with safety issues with statins?. ### Response: Japanese, Chinese, Malay, and Asian Indians.


Instruction: What is the baseline serum CK values higher in in blacks than in whites? What is available for assessing changes in serum ck?

Output: S4.5.1-38Baseline serum CK values are higher in blacks than in whites.S4.5.1-39 The 95th percentile race/ethnicity- specific and sexspecific serum CK normal levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the baseline serum CK values higher in in blacks than in whites? What is available for assessing changes in serum ck?. ### Response: S4.5.1-38Baseline serum CK values are higher in blacks than in whites.S4.5.1-39 The 95th percentile race/ethnicity- specific and sexspecific serum CK normal levels.


Instruction: What should be taken into account when prescribing dose of rosuvastatin?

Output: Asian race

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be taken into account when prescribing dose of rosuvastatin?. ### Response: Asian race.


Instruction: In adults of East Asian descent, other statins should be used preferentially over what?

Output: simvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adults of East Asian descent, other statins should be used preferentially over what?. ### Response: simvastatin.


Instruction: What characterizes a diverse portion of the world's population?

Output: Asian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What characterizes a diverse portion of the world's population?. ### Response: Asian.


Instruction: Which countries make up the most of the South Asian group?

Output: Bangladesh, India, Nepal, Pakistan, and Sri Lanka

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which countries make up the most of the South Asian group?. ### Response: Bangladesh, India, Nepal, Pakistan, and Sri Lanka.


Instruction: What is the name of the group of people from Japan, Korea, and China?

Output: East Asian group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group of people from Japan, Korea, and China?. ### Response: East Asian group.


Instruction: The term Hispanics/Latinos in the US characterizes a diverse population group.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The term Hispanics/Latinos in the US characterizes a diverse population group.. ### Response: †.


Instruction: What does ASCVD indicate?

Output: atherosclerotic cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ASCVD indicate?. ### Response: atherosclerotic cardiovascular disease.


Instruction: What does CAC stand for?

Output: coronary artery calcium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CAC stand for?. ### Response: coronary artery calcium.


Instruction: Where does the ancestry of black and Native Americans go?

Output: Europe to America

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does the ancestry of black and Native Americans go?. ### Response: Europe to America.


Instruction: What is the acronym for creatine kinase?

Output: CK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for creatine kinase?. ### Response: CK.


Instruction: What does DASH stand for?

Output: Dietary Approaches to Stop Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does DASH stand for?. ### Response: Dietary Approaches to Stop Hypertension.


Instruction: How does DM stand for diabetes mellitus?

Output: type 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does DM stand for diabetes mellitus?. ### Response: type 2.


Instruction: Which acronym stands for multi-ethnic study of atherosclerosis?

Output: MESA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which acronym stands for multi-ethnic study of atherosclerosis?. ### Response: MESA.


Instruction: What does PCE stand for?

Output: pooled cohort equations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PCE stand for?. ### Response: pooled cohort equations.


Instruction: What is the name of the pooled cohort equations?

Output: PCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pooled cohort equations?. ### Response: PCE.


Instruction: When was the PCE downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the PCE downloaded?. ### Response: April 28, 2023.


Instruction: What is a result of endothelial dysfunction and decreased nitric oxide avail-ability related to mechanical and inflammatory injury of arter-ies?

Output: increased arterial stiffness and the development of isolated systolic hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a result of endothelial dysfunction and decreased nitric oxide avail-ability related to mechanical and inflammatory injury of arter-ies?. ### Response: increased arterial stiffness and the development of isolated systolic hypertension.


Instruction: What is associated with increased arterial stiffness and the development of isolated systolic hypertension?

Output: Endothelial dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with increased arterial stiffness and the development of isolated systolic hypertension?. ### Response: Endothelial dysfunction.


Instruction: A decline in flow-mediated vasodilator capacity attributable to decreased endothelium-derived nitrate occurs in what?

Output: aging and subclini-cal vascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A decline in flow-mediated vasodilator capacity attributable to decreased endothelium-derived nitrate occurs in what?. ### Response: aging and subclini-cal vascular disease.


Instruction: What is responsible for the exaggerated exercise-induced increases in BP seen in these population groups?

Output: Impaired endothelium-mediated vaso-dilation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is responsible for the exaggerated exercise-induced increases in BP seen in these population groups?. ### Response: Impaired endothelium-mediated vaso-dilation.


Instruction: What is a critical feature of both hypertension and atherogenesis?

Output: Oxidative stress

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a critical feature of both hypertension and atherogenesis?. ### Response: Oxidative stress.


Instruction: What are the principal effectors of oxidative injury in vascular tissue?

Output: NAD(P)H oxidases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the principal effectors of oxidative injury in vascular tissue?. ### Response: NAD(P)H oxidases.


Instruction: What are NAD(P)H oxidases acti-vated by?

Output: Angiotensin II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are NAD(P)H oxidases acti-vated by?. ### Response: Angiotensin II.


Instruction: In what setting are several isoforms expressed in endo-thelial and vascular smooth muscle cells upregulated in the setting of atherosclerosis?

Output: NAD(P)H oxidase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what setting are several isoforms expressed in endo-thelial and vascular smooth muscle cells upregulated in the setting of atherosclerosis?. ### Response: NAD(P)H oxidase.


Instruction: What is upregulated in the setting of atherosclerosis and arterial injury?

Output: NAD(P)H oxidase isoforms expressed in endo-thelial and vascular smooth muscle cells

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is upregulated in the setting of atherosclerosis and arterial injury?. ### Response: NAD(P)H oxidase isoforms expressed in endo-thelial and vascular smooth muscle cells.


Instruction: Angiotensin II receptor-dependent activation of NAD(P)H oxidase stim-ulates formation of what?

Output: low-density lipoprotein cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Angiotensin II receptor-dependent activation of NAD(P)H oxidase stim-ulates formation of what?. ### Response: low-density lipoprotein cholesterol.


Instruction: What reacts with nitric oxide to form the powerful oxidant per-oxynitrite?

Output: ant superoxide anion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reacts with nitric oxide to form the powerful oxidant per-oxynitrite?. ### Response: ant superoxide anion.


Instruction: What contributes to the vasoconstrictor response to angiotensin II and elevates BP?

Output: reduction in nitric oxide bioactivity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What contributes to the vasoconstrictor response to angiotensin II and elevates BP?. ### Response: reduction in nitric oxide bioactivity.


Instruction: What stimulates oxidation of low-density lipoprotein cholesterol and increases expression of monocyte chemoattractant protein-1?

Output: Angiotensin II–induced activa-tion of NAD(P)H oxidase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What stimulates oxidation of low-density lipoprotein cholesterol and increases expression of monocyte chemoattractant protein-1?. ### Response: Angiotensin II–induced activa-tion of NAD(P)H oxidase.


Instruction: What molecule links activation of the RAAS to the atherosclerotic process?

Output: vascular cell adhe-sion molecule-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What molecule links activation of the RAAS to the atherosclerotic process?. ### Response: vascular cell adhe-sion molecule-1.


Instruction: What do many of the mechanisms that initiate and maintain hyper-tension also damage?

Output: target organs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do many of the mechanisms that initiate and maintain hyper-tension also damage?. ### Response: target organs.


Instruction: Angiotensin II elevates BP and promotes what?

Output: target-organ damage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Angiotensin II elevates BP and promotes what?. ### Response: target-organ damage.


Instruction: What promotes target-organ damage, including atherosclerosis?

Output: Angiotensin II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What promotes target-organ damage, including atherosclerosis?. ### Response: Angiotensin II.


Instruction: What can mimic or mimic aldosterone?

Output: angiotensin II and norepinephrine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can mimic or mimic aldosterone?. ### Response: angiotensin II and norepinephrine.


Instruction: What can aldosterone mimic or potiate the vasotoxic properties of angiotensin II and norepinephrine?

Output: hormones

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can aldosterone mimic or potiate the vasotoxic properties of angiotensin II and norepinephrine?. ### Response: hormones.


Instruction: What promotes cardiac and vascular smooth muscle cell hypertrophy?

Output: Angiotensin II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What promotes cardiac and vascular smooth muscle cell hypertrophy?. ### Response: Angiotensin II.


Instruction: How does AT1 receptor activation contribute to endothelial damage and athero-genesis?

Output: by inhibiting the mobilization of endothelial progeni-tor cells from the bone marrow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does AT1 receptor activation contribute to endothelial damage and athero-genesis?. ### Response: by inhibiting the mobilization of endothelial progeni-tor cells from the bone marrow.


Instruction: What is one of the causes of AT1 activation?

Output: endothelial damage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the causes of AT1 activation?. ### Response: endothelial damage.


Instruction: Ensure 5 min of quiet rest before BP measurements.

Output: 1.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ensure 5 min of quiet rest before BP measurements.. ### Response: 1..


Instruction: Sit correctly: – Sit with back straight and supported.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sit correctly: – Sit with back straight and supported.. ### Response: •.


Instruction: What should be placed directly above the antecubital fossa?

Output: Bottom of the cuff

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be placed directly above the antecubital fossa?. ### Response: Bottom of the cuff.


Instruction: Where should the bottom of the cuff be placed?

Output: directly above the antecubital fossa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where should the bottom of the cuff be placed?. ### Response: directly above the antecubital fossa.


Instruction: Where is the antecubital fossa located?

Output: bend of the elbow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the antecubital fossa located?. ### Response: bend of the elbow.


Instruction: How many readings should you take in the morning before taking medications?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many readings should you take in the morning before taking medications?. ### Response: 2.


Instruction: What should you do in the evening before supper?

Output: Take multiple readings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should you do in the evening before supper?. ### Response: Take multiple readings.


Instruction: Ideally, measure and record how often?

Output: daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ideally, measure and record how often?. ### Response: daily.


Instruction: What should be brought to all clinic appointments?

Output: Monitors with built-in memory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be brought to all clinic appointments?. ### Response: Monitors with built-in memory.


Instruction: How often should BP readings be obtained?

Output: weekly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often should BP readings be obtained?. ### Response: weekly.


Instruction: What should monitors with built-in memory be brought?

Output: all clinic appointments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should monitors with built-in memory be brought?. ### Response: all clinic appointments.


Instruction: BP should be based on an average of readings on 2 occasions for what?

Output: clinical decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BP should be based on an average of readings on 2 occasions for what?. ### Response: clinical decision making.


Instruction: What is recommended to confirm the diagnosis of hypertension and for titration of BP-lowering medication?

Output: Out-of-office BP measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to confirm the diagnosis of hypertension and for titration of BP-lowering medication?. ### Response: Out-of-office BP measurements.


Instruction: What indicates American College of Cardiology?

Output: 47–50 (Class 1, Level of Evidence: ASR)ACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates American College of Cardiology?. ### Response: 47–50 (Class 1, Level of Evidence: ASR)ACC.


Instruction: AHA, American Heart Association; BP, what?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AHA, American Heart Association; BP, what?. ### Response: blood pressure.


Instruction: What is HBP?

Output: high blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HBP?. ### Response: high blood pressure.


Instruction: What is HBPM?

Output: home blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HBPM?. ### Response: home blood pressure monitoring.


Instruction: Where is QCDR available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is QCDR available?. ### Response: http://ahajournals.org.


Instruction: What may be associated with a high incidence of intracranial hemorrhage?

Output: Carotid stenting and intracranial thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with a high incidence of intracranial hemorrhage?. ### Response: Carotid stenting and intracranial thrombectomy.


Instruction: What year did J Neurointerv Surg. 2015:7:170–175.

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Neurointerv Surg. 2015:7:170–175.. ### Response: 2014.


Instruction: What is the name of the glycoprotein IIb/IIIa inhibitor that bridg-ing and subsequent endovascular therapy in vertebrobasilar occlusion in 120 patients?

Output: Ernst M, Butscheid F, Fiehler J, Wittkugel O, Alfke K, Jansen O, Petersen D, Koch C, Eckert B.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the glycoprotein IIb/IIIa inhibitor that bridg-ing and subsequent endovascular therapy in vertebrobasilar occlusion in 120 patients?. ### Response: Ernst M, Butscheid F, Fiehler J, Wittkugel O, Alfke K, Jansen O, Petersen D, Koch C, Eckert B..


Instruction: What are the names of the patients who were treated with bridging?

Output: 120

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the patients who were treated with bridging?. ### Response: 120.


Instruction: What is the name of the research group that investigated the influence of device choice on the MR CLEAN Investigators?

Output: ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the research group that investigated the influence of device choice on the MR CLEAN Investigators?. ### Response: ahajournals.org.


Instruction: When will the paper be available for download from http://ahajournals.org?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the paper be available for download from http://ahajournals.org?. ### Response: April 28, 2023.


Instruction: How long are Guideline Writing Committee members and reviewers required to disclose current industry rela-tionships or personal interests?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long are Guideline Writing Committee members and reviewers required to disclose current industry rela-tionships or personal interests?. ### Response: 12 months.


Instruction: What does management of RWI involve?

Output: selecting a balanced GWC and assuring thatthe chair and a majority of committee members haveno relevant RWI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does management of RWI involve?. ### Response: selecting a balanced GWC and assuring thatthe chair and a majority of committee members haveno relevant RWI.


Instruction: What does the Task Force strive to avoid by selecting experts from a broad range of sources?

Output: bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Task Force strive to avoid by selecting experts from a broad range of sources?. ### Response: bias.


Instruction: What are members restricted with regard to writing or voting on?

Output: sectionsto which their RWI apply

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are members restricted with regard to writing or voting on?. ### Response: sectionsto which their RWI apply.


Instruction: What does Force strive to avoid by selecting experts from a broad array of backgrounds?

Output: bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Force strive to avoid by selecting experts from a broad array of backgrounds?. ### Response: bias.


Instruction: Force invites organizations and professional societies with relatedinterests and expertise to participate as partners or col-laborators?

Output: The Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Force invites organizations and professional societies with relatedinterests and expertise to participate as partners or col-laborators?. ### Response: The Task Force.


Instruction: What is standardized terminology for articulating recommendations?

Output: structure of evidence tables and summaries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is standardized terminology for articulating recommendations?. ### Response: structure of evidence tables and summaries.


Instruction: What is the focus of the 2015 ACC/AHA/SCAI Focused Update on Primary PCI 1003Catheterization?

Output: Cardiovascular Interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the 2015 ACC/AHA/SCAI Focused Update on Primary PCI 1003Catheterization?. ### Response: Cardiovascular Interventions.


Instruction: What is the focus of the 2015 ACC/AHA/SCAI Focused Update on Primary PCI 1003Catheterization and Cardiovascular Interventions DOI 10.1002/ccd.Published on behalf of The Society for Cardiovascular Angiography and Interventions (SCAI)?

Output: periodic assessment and updating

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the 2015 ACC/AHA/SCAI Focused Update on Primary PCI 1003Catheterization and Cardiovascular Interventions DOI 10.1002/ccd.Published on behalf of The Society for Cardiovascular Angiography and Interventions (SCAI)?. ### Response: periodic assessment and updating.


Instruction: When was this updated?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this updated?. ### Response: 2015.


Instruction: What are the terms and conditions on Wiley Online Library for?

Output: rules of use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the terms and conditions on Wiley Online Library for?. ### Response: rules of use.


Instruction: What is the applicable Creative Commons License for OA articles?

Output: Terms and Conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the applicable Creative Commons License for OA articles?. ### Response: Terms and Conditions.


Instruction: What should be given as early as possible or at time of primary PCI to patients with STEMI?

Output: A loading dose of a P2Y12 receptor inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given as early as possible or at time of primary PCI to patients with STEMI?. ### Response: A loading dose of a P2Y12 receptor inhibitor.


Instruction: What is a loading dose of a P2Y12 receptor inhibitor?

Output: as early as possible

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a loading dose of a P2Y12 receptor inhibitor?. ### Response: as early as possible.


Instruction: How long should P2Y12 inhibitor therapy be given to patients with STEMI?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should P2Y12 inhibitor therapy be given to patients with STEMI?. ### Response: 1 year.


Instruction: What is the level of evidence of primary PCI to STEMI patients?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence of primary PCI to STEMI patients?. ### Response: B.


Instruction: How long can Clopidogrel be given to STEMI patients?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long can Clopidogrel be given to STEMI patients?. ### Response: 1 year.


Instruction: What is the level of evidence for Prasugrel?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for Prasugrel?. ### Response: B.


Instruction: How many times a day is Ticagrelor 90 mg?

Output: twice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times a day is Ticagrelor 90 mg?. ### Response: twice.


Instruction: How many mg of aspirin is recommended after primary PCI?

Output: 81

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg of aspirin is recommended after primary PCI?. ### Response: 81.


Instruction: What is the level of evidence for daily262?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for daily262?. ### Response: B.


Instruction: What is a Level of Evidence?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Level of Evidence?. ### Response: B.


Instruction: What is an intravenous GP IIb/IIIa receptor antagonist?

Output: Prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an intravenous GP IIb/IIIa receptor antagonist?. ### Response: Prasugrel.


Instruction: What type of PCI is used in STEMI patients?

Output: primary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of PCI is used in STEMI patients?. ### Response: primary.


Instruction: What is the class of heparin used for?

Output: unfractionated heparin (UFH).Class IIb1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of heparin used for?. ### Response: unfractionated heparin (UFH).Class IIb1.


Instruction: In what laboratory setting is GP IIb/IIIa receptor antagonist used?

Output: precatheteriza-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what laboratory setting is GP IIb/IIIa receptor antagonist used?. ### Response: precatheteriza-tion.


Instruction: What may be reasonable to administer intracoronary ab-ciximab to patients with STEMI undergoing primary PCI?

Output: A loading dose of a P2Y12 receptor inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable to administer intracoronary ab-ciximab to patients with STEMI undergoing primary PCI?. ### Response: A loading dose of a P2Y12 receptor inhibitor.


Instruction: What can be considered in patients undergoing DES place-ment?

Output: Continuation of a P2Y12 inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be considered in patients undergoing DES place-ment?. ### Response: Continuation of a P2Y12 inhibitor.


Instruction: What may be considered in patients undergoing DES place-ment?

Output: Continuation of a P2Y12 inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered in patients undergoing DES place-ment?. ### Response: Continuation of a P2Y12 inhibitor.


Instruction: What should not be administered to patients with a history of prior stroke or transient ischemic attack?

Output: Prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be administered to patients with a history of prior stroke or transient ischemic attack?. ### Response: Prasugrel.


Instruction: What does the writ-ing committee recommend?

Output: an empiric dose of 325 mg be given as early as possible before PCI and a maintenance dose continued indefinitely thereafter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writ-ing committee recommend?. ### Response: an empiric dose of 325 mg be given as early as possible before PCI and a maintenance dose continued indefinitely thereafter.


Instruction: What is the empiric dose of 325 mg given as early as possible before PCI?

Output: 81-mg maintenance dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the empiric dose of 325 mg given as early as possible before PCI?. ### Response: 81-mg maintenance dose.


Instruction: What is the recommended maintenance dose of aspirin to be used with ticagrelor?

Output: 81 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended maintenance dose of aspirin to be used with ticagrelor?. ### Response: 81 mg daily.


Instruction: What does the writing committee agree is preferred even among patients who receive a stent during primary PCI?

Output: 81-mg maintenance dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing committee agree is preferred even among patients who receive a stent during primary PCI?. ### Response: 81-mg maintenance dose.


Instruction: How is daily.recommendation based on evidence of an increased risk of bleeding?

Output: 81 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is daily.recommendation based on evidence of an increased risk of bleeding?. ### Response: 81 mg.


Instruction: What is the absence of data from RCTs?

Output: recommendation is based on evidence of an increased risk of bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the absence of data from RCTs?. ### Response: recommendation is based on evidence of an increased risk of bleeding.


Instruction: What is a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American Collegiate of Surgeons and American Dental Association?

Output: Prevention of premature discontinuation of dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American Collegiate of Surgeons and American Dental Association?. ### Response: Prevention of premature discontinuation of dual antiplatelet therapy.


Instruction: Who represented the American College of Surgeons?

Output: American College of Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who represented the American College of Surgeons?. ### Response: American College of Physicians.


Instruction: What is the name of the journal that represents the American Dental Association?

Output: American College of Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that represents the American Dental Association?. ### Response: American College of Physicians.


Instruction: When was the Circulation. 2007:115:813–18.

Output: 30

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation. 2007:115:813–18.. ### Response: 30.


Instruction: What was the out-come of thrombosis after successful implantation of drug-eluting stents.

Output: Incidence, predictors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the out-come of thrombosis after successful implantation of drug-eluting stents.. ### Response: Incidence, predictors.


Instruction: What type of stents are used in renal disease?

Output: drug-eluting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stents are used in renal disease?. ### Response: drug-eluting.


Instruction: What is the importance of the glomerular filtration rate formula for classification of kidney disease in patients with non-ST-segment elevation acute coronary syndromes?

Output: Cockcroft-Gault versus modi-fication of diet in renal disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the importance of the glomerular filtration rate formula for classification of kidney disease in patients with non-ST-segment elevation acute coronary syndromes?. ### Response: Cockcroft-Gault versus modi-fication of diet in renal disease.


Instruction: What is a syndrome?

Output: non-ST-segment elevation acute coronary syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a syndrome?. ### Response: non-ST-segment elevation acute coronary syndromes.


Instruction: What is the name of the journal that published the study?

Output: JAMA. 2005;293:2126–30. 31. Melloni C, Peterson ED, Chen AY , et al. Cockcroft-Gault versus modi-fication of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes. J Am Coll Cardiol 2008;51:991–6.Downloaded from http://ahajournals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published the study?. ### Response: JAMA. 2005;293:2126–30. 31. Melloni C, Peterson ED, Chen AY , et al. Cockcroft-Gault versus modi-fication of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes. J Am Coll Cardiol 2008;51:991–6.Downloaded from http://ahajournals.


Instruction: When was the study released?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the study released?. ### Response: May 3, 2023.


Instruction: What is the ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease?

Output: ENDS are useful or effective for tobacco treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: ENDS are useful or effective for tobacco treatment.


Instruction: What is ENDS used for?

Output: tobacco treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ENDS used for?. ### Response: tobacco treatment.