Instruction: What is the name of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol?

Output: Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol?. ### Response: Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines?

Output: AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines?. ### Response: AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol.


Instruction: How many people participated in a meta-analysis of data from 26 randomised trials?

Output: 170 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people participated in a meta-analysis of data from 26 randomised trials?. ### Response: 170 000.


Instruction: When did the Lancet issue 376:1670–81?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet issue 376:1670–81?. ### Response: 2010.


Instruction: What is the name of the group that collaborates with the CTT Collaboration?

Output: Cholesterol Treatment Trialists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that collaborates with the CTT Collaboration?. ### Response: Cholesterol Treatment Trialists.


Instruction: What is the name of the randomised placebo-controlled trial of simvastatin and ezetimibe in patients with chronic kidney disease?

Output: Study of Heart and Renal Protection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised placebo-controlled trial of simvastatin and ezetimibe in patients with chronic kidney disease?. ### Response: Study of Heart and Renal Protection.


Instruction: What is another name for the Cholesterol Treatment Trialists’ Collaboration?

Output: CTT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the Cholesterol Treatment Trialists’ Collaboration?. ### Response: CTT.


Instruction: When was the Lancet 376:1670-81?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet 376:1670-81?. ### Response: 2010.


Instruction: What is the acronym for Cholesterol Treatment Trialists' Collaboration?

Output: CTT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Cholesterol Treatment Trialists' Collaboration?. ### Response: CTT.


Instruction: What does CTT stand for?

Output: Cholesterol Treatment Trialists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CTT stand for?. ### Response: Cholesterol Treatment Trialists.


Instruction: How many randomised trials were included in the meta-analysis?

Output: 28

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomised trials were included in the meta-analysis?. ### Response: 28.


Instruction: What is the name of the systematic review of statin use for the prevention of cardiovascular disease in adults?

Output: US Preventive Services Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of statin use for the prevention of cardiovascular disease in adults?. ### Response: US Preventive Services Task Force.


Instruction: Where is the US Agency for Healthcare Research and Quality?

Output: Rockville, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the US Agency for Healthcare Research and Quality?. ### Response: Rockville, MD.


Instruction: When was the report no. 14-05206-EF-2 released?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the report no. 14-05206-EF-2 released?. ### Response: 2016.


Instruction: Where is lovastatin available?

Output: http://www.ncbi.nlm.nih.gov/books/NBK396415. Accessed January 5, 2019. S4.3-6. Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cho-lesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is lovastatin available?. ### Response: http://www.ncbi.nlm.nih.gov/books/NBK396415. Accessed January 5, 2019. S4.3-6. Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cho-lesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study.


Instruction: Where is Rockville, MD?

Output: US Agency for Healthcare Research and Quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Rockville, MD?. ### Response: US Agency for Healthcare Research and Quality.


Instruction: What is the name of the primary prevention of acute coronary events?

Output: lovastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the primary prevention of acute coronary events?. ### Response: lovastatin.


Instruction: What is rosuvastatin to prevent in men and women with elevated C-reactive protein?

Output: vascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rosuvastatin to prevent in men and women with elevated C-reactive protein?. ### Response: vascular events.


Instruction: What is the name of the study that was published in 1998?

Output: UK Prospective Diabetes Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that was published in 1998?. ### Response: UK Prospective Diabetes Study.


Instruction: What is Sertraline used for in patients with MI or unstable angina?

Output: major depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Sertraline used for in patients with MI or unstable angina?. ### Response: major depression.


Instruction: What is the name of the study that examined depressive symptoms and quality of life?

Output: Heart and Soul Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined depressive symptoms and quality of life?. ### Response: Heart and Soul Study.


Instruction: When was the Heart and Soul Study conducted?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Heart and Soul Study conducted?. ### Response: 2003.


Instruction: What predictsmortality and hospitalization in patients with myocardial infarctioncomplicated by heart failure?

Output: Depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predictsmortality and hospitalization in patients with myocardial infarctioncomplicated by heart failure?. ### Response: Depression.


Instruction: What causes myocardial infarction?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes myocardial infarction?. ### Response: heart failure.


Instruction: What is the name of the study that found social networks are associated with lower mortality rates among women with suspected coronarydisease?

Output: National Heart, Lung, and Blood Institute-Spo nsoredWomen’s Ischemia Syndrome Evaluation study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that found social networks are associated with lower mortality rates among women with suspected coronarydisease?. ### Response: National Heart, Lung, and Blood Institute-Spo nsoredWomen’s Ischemia Syndrome Evaluation study.


Instruction: What is the National Heart, Lung and Blood Institute-Spo nsoredWomen's Ischemia Syndrome Evaluation study?

Output: suspected coronarydisease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the National Heart, Lung and Blood Institute-Spo nsoredWomen's Ischemia Syndrome Evaluation study?. ### Response: suspected coronarydisease.


Instruction: What predicts an increased risk of death ormyocardial infarction after angiographic diagnosis of coronary disease?

Output: Less affluent area ofresidence and lesser-insured status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts an increased risk of death ormyocardial infarction after angiographic diagnosis of coronary disease?. ### Response: Less affluent area ofresidence and lesser-insured status.


Instruction: How many cases of myocardial infarction were there?

Output: 11119

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of myocardial infarction were there?. ### Response: 11119.


Instruction: How many controls were there in the INTERHEART study?

Output: 13648

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many controls were there in the INTERHEART study?. ### Response: 13648.


Instruction: What is the name of the case-control study conducted in 2004?

Output: INTERHEART study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the case-control study conducted in 2004?. ### Response: INTERHEART study.


Instruction: What predicts total mortality among outpatients with coronaryartery disease?

Output: Anginal symptomscons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts total mortality among outpatients with coronaryartery disease?. ### Response: Anginal symptomscons.


Instruction: When did Spertus JA, Jones P, McDonell M, et al. publish their findings?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Spertus JA, Jones P, McDonell M, et al. publish their findings?. ### Response: 2004.


Instruction: What is the name of the model used to predict long-term survival after exercise treadmill testing inpatients with suspected coronary artery disease and a normal electro-cardiogram?

Output: externally validated model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the model used to predict long-term survival after exercise treadmill testing inpatients with suspected coronary artery disease and a normal electro-cardiogram?. ### Response: externally validated model.


Instruction: Ann Intern Med. 2007;147:821-8.249.

Output: coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ann Intern Med. 2007;147:821-8.249.. ### Response: coronary artery disease.


Instruction: Hubbard BL, Gibbons RJ, Lapeyre AC III, et al.

Output: Identification ofsevere coronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hubbard BL, Gibbons RJ, Lapeyre AC III, et al.. ### Response: Identification ofsevere coronary.


Instruction: What did AC III identify using simple clinical parameters?

Output: severe coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did AC III identify using simple clinical parameters?. ### Response: severe coronary artery disease.


Instruction: What did Ho K-T, Miller TD, Hodge DO, et al. use to predict prognosis of patients with normal or mildly abnormal resting electrocardiographic findingsundergoing evaluation for coronaryartery disease?

Output: a simple clinical score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Ho K-T, Miller TD, Hodge DO, et al. use to predict prognosis of patients with normal or mildly abnormal resting electrocardiographic findingsundergoing evaluation for coronaryartery disease?. ### Response: a simple clinical score.


Instruction: What is undergoing evaluation for coronaryartery disease?

Output: electrocardiographic findings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is undergoing evaluation for coronaryartery disease?. ### Response: electrocardiographic findings.


Instruction: What does a simple clinical score predict?

Output: outcome in a community-based populati onundergoing stress testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a simple clinical score predict?. ### Response: outcome in a community-based populati onundergoing stress testing.


Instruction: What is under fire: on the management ofstable coronary disease?

Output: Diamond GA, Kaul S. COURAGE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is under fire: on the management ofstable coronary disease?. ### Response: Diamond GA, Kaul S. COURAGE.


Instruction: When did J Am Coll Cardiol. 2007;50:1604–9.253.

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2007;50:1604–9.253.. ### Response: 2007.


Instruction: What is C-reactive protein as a risk factor for?

Output: coronaryartery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is C-reactive protein as a risk factor for?. ### Response: coronaryartery disease.


Instruction: What is the class of LV dysfunction?

Output: Class IIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of LV dysfunction?. ### Response: Class IIa.


Instruction: What can be added to the basic regimen of  -blocker, ACE inhibitor, and thiazide?

Output: a long-acting dihydropyridine CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be added to the basic regimen of  -blocker, ACE inhibitor, and thiazide?. ### Response: a long-acting dihydropyridine CCB.


Instruction: What should be used with cau-tion in patients with symptomatic CAD and hypertension?

Output: The combination of a β -blocker and either of the nondihydropyridine CCBs (diltiazem or verapamil)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used with cau-tion in patients with symptomatic CAD and hypertension?. ### Response: The combination of a β -blocker and either of the nondihydropyridine CCBs (diltiazem or verapamil).


Instruction: What is the increased risk of significant brady-arrhythmias and HF?

Output: symptomatic CAD and hyperten-sion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the increased risk of significant brady-arrhythmias and HF?. ### Response: symptomatic CAD and hyperten-sion.


Instruction: For patients with stable angina, the BP target is what?

Output: <140/90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients with stable angina, the BP target is what?. ### Response: <140/90 mm Hg.


Instruction: What is the BP target for patients with stable angina?

Output: <140/90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BP target for patients with stable angina?. ### Response: <140/90 mm Hg.


Instruction: What is a lower target BP in some individuals with CAD?

Output: (<130/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a lower target BP in some individuals with CAD?. ### Response: (<130/80 mm Hg.


Instruction: What are some individuals with CAD risk equivalents?

Output: carotid artery disease, PAD, abdomi-nal aort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some individuals with CAD risk equivalents?. ### Response: carotid artery disease, PAD, abdomi-nal aort.


Instruction: What is a class IIb; Level of Evidence B?

Output: CAD risk equivalents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIb; Level of Evidence B?. ### Response: CAD risk equivalents.


Instruction: There are no special contraindications for the use of what drugs?

Output: antiplatelet or anticoagu-lant drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are no special contraindications for the use of what drugs?. ### Response: antiplatelet or anticoagu-lant drugs.


Instruction: What should be lowered with-out delay in patients with uncontrolled severe hypertension who are taking antiplatelet or anticoagulant drugs?

Output: the BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be lowered with-out delay in patients with uncontrolled severe hypertension who are taking antiplatelet or anticoagulant drugs?. ### Response: the BP.


Instruction: What should reduce the risk of hemorrhagic stroke?

Output: the BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should reduce the risk of hemorrhagic stroke?. ### Response: the BP.


Instruction: What is a major risk factor for CVD?

Output: brady-arrhythmias and HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major risk factor for CVD?. ### Response: brady-arrhythmias and HF.


Instruction: What is the impact of hyper -tension on ACS outcomes not well described?

Output: major risk factor for CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of hyper -tension on ACS outcomes not well described?. ### Response: major risk factor for CVD.


Instruction: How many data are available on specific treatments for hypertension in patients with STEMI or non-ST-segment-elevation ACS?

Output: Few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many data are available on specific treatments for hypertension in patients with STEMI or non-ST-segment-elevation ACS?. ### Response: Few.


Instruction: What is a non-ST-segment-elevation ACS?

Output: STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a non-ST-segment-elevation ACS?. ### Response: STEMI.


Instruction: What is the ACTION Registry-Get With The Guidelines?

Output: Acute Coronary Treatment and Intervention Outcomes Network

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACTION Registry-Get With The Guidelines?. ### Response: Acute Coronary Treatment and Intervention Outcomes Network.


Instruction: What is the prevalence of hypertension among ACS patients?

Output: double

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of hypertension among ACS patients?. ### Response: double.


Instruction: What percentage of patients with STEMI have hypertension?

Output: 65.2%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with STEMI have hypertension?. ### Response: 65.2%.


Instruction: How much do hypertension prevalence rates double among individuals >75 versus those 45?

Output: double

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much do hypertension prevalence rates double among individuals >75 versus those 45?. ### Response: double.


Instruction: What is the impact of hypertension on outcomes in ACS?

Output: com-plex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of hypertension on outcomes in ACS?. ### Response: com-plex.


Instruction: In patients with stabilized ACS, what was an independent predictor of death and MI at 90 days?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with stabilized ACS, what was an independent predictor of death and MI at 90 days?. ### Response: hypertension.


Instruction: What is a predictor of death and MI at 90 days?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of death and MI at 90 days?. ### Response: hypertension.


Instruction: Hypertension is integrated into the Thrombolysis in Myocardial Infarction risk score for UA/NSTEMI as one of several classic risk factors for CAD?

Output: 179

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertension is integrated into the Thrombolysis in Myocardial Infarction risk score for UA/NSTEMI as one of several classic risk factors for CAD?. ### Response: 179.


Instruction: What was independently associated with the composite end point of mortality and recurrent ischemic events?

Output: the variable of ≥ 3 risk factors for CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was independently associated with the composite end point of mortality and recurrent ischemic events?. ### Response: the variable of ≥ 3 risk factors for CAD.


Instruction: When do early afterdepolarizations occur during late phase 2 or early phase 3 of the action potential?

Output: Delayed afterdepolarizations occur after complete membrane repolarization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When do early afterdepolarizations occur during late phase 2 or early phase 3 of the action potential?. ### Response: Delayed afterdepolarizations occur after complete membrane repolarization.


Instruction: What type of myocytes and Purkinje fibers may enhance normal automaticity in ischemic zone?

Output: ventricular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of myocytes and Purkinje fibers may enhance normal automaticity in ischemic zone?. ### Response: ventricular.


Instruction: What is an increase in inward currents called?

Output: the late sodium cur -rent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increase in inward currents called?. ### Response: the late sodium cur -rent.


Instruction: What is a decrease in repolarizing potassium current?

Output: increase in inward currents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a decrease in repolarizing potassium current?. ### Response: increase in inward currents.


Instruction: What may occur when reacti-vation of the inward L-type calcium channel occurs before the membrane has returned to a more nega-tive potential than that required for calcium channel reactivation?

Output: early afterdepolarizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may occur when reacti-vation of the inward L-type calcium channel occurs before the membrane has returned to a more nega-tive potential than that required for calcium channel reactivation?. ### Response: early afterdepolarizations.


Instruction: Spontaneous calcium release from what may result in spontaneous calcium release?

Output: sarcoplasmic retic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Spontaneous calcium release from what may result in spontaneous calcium release?. ### Response: sarcoplasmic retic.


Instruction: What may result in activation of a depolarizing sodium/calcium exchange current?

Output: Spontaneous calcium release

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may result in activation of a depolarizing sodium/calcium exchange current?. ### Response: Spontaneous calcium release.


Instruction: What is the trigger for torsades de pointes VT?

Output: Early afterdepolarizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the trigger for torsades de pointes VT?. ### Response: Early afterdepolarizations.


Instruction: What is the trigger that culminates in polymorphic VT/VF?

Output: early afterdepolarization/triggered activity sequence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the trigger that culminates in polymorphic VT/VF?. ### Response: early afterdepolarization/triggered activity sequence.


Instruction: What happens after complete membrane repolarization and develop under condi-tions of intracellular calcium overload?

Output: Delayed afterdepolarizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What happens after complete membrane repolarization and develop under condi-tions of intracellular calcium overload?. ### Response: Delayed afterdepolarizations.


Instruction: What causes tachycardia, catecholamines, hypokalemia, digoxin toxicity, cardiac hypertrophy, and HF?

Output: elevated intracellular calcium load

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes tachycardia, catecholamines, hypokalemia, digoxin toxicity, cardiac hypertrophy, and HF?. ### Response: elevated intracellular calcium load.


Instruction: What can initiate spontaneous calci-um release?

Output: sarcoplasmic reticulum

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can initiate spontaneous calci-um release?. ### Response: sarcoplasmic reticulum.


Instruction: What is the underlying mechanism for VT in the setting of digoxin toxicity?

Output: Delayed afterdepolar -izations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the underlying mechanism for VT in the setting of digoxin toxicity?. ### Response: Delayed afterdepolar -izations.


Instruction: What is driven predominantly by the sodium–calcium exchange current?

Output: transient inward current

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is driven predominantly by the sodium–calcium exchange current?. ### Response: transient inward current.


Instruction: What is an impor -tant trigger of VA in the setting of HF?

Output: Delayed af-terdepolarizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an impor -tant trigger of VA in the setting of HF?. ### Response: Delayed af-terdepolarizations.


Instruction: What cells are more susceptible to spontaneous sarcoplasmic re-ticulum calcium release than ventricular myocytes sug-ging that delayed af-terdepolarizations?

Output: Purkinje

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What cells are more susceptible to spontaneous sarcoplasmic re-ticulum calcium release than ventricular myocytes sug-ging that delayed af-terdepolarizations?. ### Response: Purkinje.


Instruction: What may be an important mechanism for some Purkinje fiber-related VA?

Output: delayed afterdepolarizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be an important mechanism for some Purkinje fiber-related VA?. ### Response: delayed afterdepolarizations.


Instruction: What is the underlying mechanism for most sustained VA in the presence of structural heart disease?

Output: ReentryReentry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the underlying mechanism for most sustained VA in the presence of structural heart disease?. ### Response: ReentryReentry.


Instruction: What happens around a fixed anatomical obstacle?

Output: Reentry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What happens around a fixed anatomical obstacle?. ### Response: Reentry.


Instruction: What is an example of an obstacle that can be fixed?

Output: scar after an MI or surgically repaired congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an obstacle that can be fixed?. ### Response: scar after an MI or surgically repaired congenital heart disease.


Instruction: How is scar after an MI repaired?

Output: surgically repaired congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is scar after an MI repaired?. ### Response: surgically repaired congenital heart disease.


Instruction: What is the name of the guideline committee that was aware that the issue of continuity is covered in the “Patient experience in care”?

Output: CG13 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline committee that was aware that the issue of continuity is covered in the “Patient experience in care”?. ### Response: CG13 8.


Instruction: What is covered in the "Patient experience in adult NHS services" NICE Clinical Guidance February 2012 (CG138)233?

Output: the issue of continuity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is covered in the "Patient experience in adult NHS services" NICE Clinical Guidance February 2012 (CG138)233?. ### Response: the issue of continuity.


Instruction: What did this review use to synthesise the heart failure specific findings from this review?

Output: the framework of the recommendations from that guidance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did this review use to synthesise the heart failure specific findings from this review?. ### Response: the framework of the recommendations from that guidance.


Instruction: What are the most relevant recommendations from CG13 8?

Output: Assess each patient’s requirement for continuity of care and how that requirement will be met

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the most relevant recommendations from CG13 8?. ### Response: Assess each patient’s requirement for continuity of care and how that requirement will be met.


Instruction: What is the term for continuity of care?

Output: Co -ordination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for continuity of care?. ### Response: Co -ordination.


Instruction: What type of care is provided for patients who use a number of services?

Output: different services (for example, services in both primary and secondary care, or attending different clinics in a hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care is provided for patients who use a number of services?. ### Response: different services (for example, services in both primary and secondary care, or attending different clinics in a hospital.


Instruction: What is one way to ensure effective coordination and prioritisation of care to minimise the impact on the patient?

Output: For patients who use a number of different services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one way to ensure effective coordination and prioritisation of care to minimise the impact on the patient?. ### Response: For patients who use a number of different services.


Instruction: Ensure clear and timely exchange of what?

Output: patient information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ensure clear and timely exchange of what?. ### Response: patient information.


Instruction: Ensure clear and timely exchange of patient information between healthcare professionals?

Output: Co -ordination)   Ensure clear and timely exchange of patient information: (Communication)  o between healthcare professionals (particularly at the point of any transitions in care)  o between healthcare and social care professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ensure clear and timely exchange of patient information between healthcare professionals?. ### Response: Co -ordination)   Ensure clear and timely exchange of patient information: (Communication)  o between healthcare professionals (particularly at the point of any transitions in care)  o between healthcare and social care professionals.


Instruction: Ensure communication between healthcare and what?

Output: social care professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ensure communication between healthcare and what?. ### Response: social care professionals.


Instruction: What does this review use to define four findings in which to group the findings?

Output: recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does this review use to define four findings in which to group the findings?. ### Response: recommendations.


Instruction: How many findings were recommendations to define?

Output: four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many findings were recommendations to define?. ### Response: four.


Instruction: How did we fit evidence to the framework?

Output: synthesise the heart failure specific findings from this review, while also collecting heart failure specific themes not covered in that guidance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did we fit evidence to the framework?. ### Response: synthesise the heart failure specific findings from this review, while also collecting heart failure specific themes not covered in that guidance.


Instruction: What did we separately collect that did not fit into the framework for synthesis?

Output: evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we separately collect that did not fit into the framework for synthesis?. ### Response: evidence.


Instruction: What group experienced signifi-cantly less major and minor bleeding?

Output: lower-intensity INR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group experienced signifi-cantly less major and minor bleeding?. ### Response: lower-intensity INR.


Instruction: What were the rates of stroke, transient ischemic attack, total neurological events and all-cause mortal-ity similar between the 2 groups?

Output: similar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the rates of stroke, transient ischemic attack, total neurological events and all-cause mortal-ity similar between the 2 groups?. ### Response: similar.


Instruction: What is the strategy of dual-antiplatelet therapy versus low-intensity anticoagulation plus low-dose aspirin?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strategy of dual-antiplatelet therapy versus low-intensity anticoagulation plus low-dose aspirin?. ### Response: clopidogrel.


Instruction: How long has the routine use of dual antiplatelet for 6 months after TAVI been the default strategy?

Output: since the introduction of this technol-ogy into clinical use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has the routine use of dual antiplatelet for 6 months after TAVI been the default strategy?. ### Response: since the introduction of this technol-ogy into clinical use.


Instruction: What has not been rigorously assessed?

Output: The routine use of dual-antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been rigorously assessed?. ### Response: The routine use of dual-antiplatelet therapy.


Instruction: What has been rigorously assessed?

Output: antithrom-botic strategies after TAVI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been rigorously assessed?. ### Response: antithrom-botic strategies after TAVI.


Instruction: There are several ongoing trials evaluating what after TAVI?

Output: antithrom-botic strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are several ongoing trials evaluating what after TAVI?. ### Response: antithrom-botic strategies.


Instruction: What did a small, single-center RCT show no difference in?

Output: a composite endpoint of major adverse cardiac and cerebro-vascular events or life-threatening bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a small, single-center RCT show no difference in?. ### Response: a composite endpoint of major adverse cardiac and cerebro-vascular events or life-threatening bleeding.


Instruction: Aspirin plus clopidogrel versus aspirin alone at 30 days and 6 months?

Output: A small, single-center RCT of patients receiving a self-expanding TAVI device showed no difference in a composite endpoint of major adverse cardiac and cerebro-vascular events or life-threatening bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin plus clopidogrel versus aspirin alone at 30 days and 6 months?. ### Response: A small, single-center RCT of patients receiving a self-expanding TAVI device showed no difference in a composite endpoint of major adverse cardiac and cerebro-vascular events or life-threatening bleeding.


Instruction: Dual-antiplatelet therapy may be associated with a higher risk of bleeding than what other type of therapy?

Output: single-agent therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dual-antiplatelet therapy may be associated with a higher risk of bleeding than what other type of therapy?. ### Response: single-agent therapy.


Instruction: What may impact the decision to use dual-antiplatelet therapy?

Output: Other procedural and patient factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may impact the decision to use dual-antiplatelet therapy?. ### Response: Other procedural and patient factors.


Instruction: What might be considered after TAVI in patients at low bleeding risk on an individual basis?

Output: The selective use of VKA therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered after TAVI in patients at low bleeding risk on an individual basis?. ### Response: The selective use of VKA therapy.


Instruction: What anticoagulant was used after TAVI in intermediate or higher risk patients?

Output: 95% warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What anticoagulant was used after TAVI in intermediate or higher risk patients?. ### Response: 95% warfarin.


Instruction: What percentage of warfarin was used in the PARTNER 2 investigators?

Output: 95%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of warfarin was used in the PARTNER 2 investigators?. ### Response: 95%.


Instruction: In the first year after implantation, what was the mean gradient?

Output: >10 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the first year after implantation, what was the mean gradient?. ### Response: >10 mm Hg.


Instruction: What may reflect the development of leaflet thrombosis?

Output: Doppler finding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may reflect the development of leaflet thrombosis?. ### Response: Doppler finding.


Instruction: What may be more effective than direct oral anticoagulants for reduction of death, myocardial infarction, and cerebrovascular events?

Output: VKAs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be more effective than direct oral anticoagulants for reduction of death, myocardial infarction, and cerebrovascular events?. ### Response: VKAs.


Instruction: What is the name of the study that compares a Rivaroxaban-based anticoagulation to a TAVI?

Output: PARTNER 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares a Rivaroxaban-based anticoagulation to a TAVI?. ### Response: PARTNER 2.


Instruction: What is a result of the selective short-term use of VKAs after ViV TAVI predicated on?

Output: valve thrombosis may be more frequent in this patient population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a result of the selective short-term use of VKAs after ViV TAVI predicated on?. ### Response: valve thrombosis may be more frequent in this patient population.


Instruction: What was the GALILEO trial?

Output: Global Study Comparing a Rivaroxaban-based Antithrombotic Strategy to an Antiplatelet-based Strategy after Transcatheter Aortic Valve Replacement to Optimize Clinical Outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the GALILEO trial?. ### Response: Global Study Comparing a Rivaroxaban-based Antithrombotic Strategy to an Antiplatelet-based Strategy after Transcatheter Aortic Valve Replacement to Optimize Clinical Outcomes.


Instruction: How many mg of rivaroxaban was used?

Output: 10 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg of rivaroxaban was used?. ### Response: 10 mg daily.


Instruction: What is the daily dose of aspirin?

Output: 75–100 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the daily dose of aspirin?. ### Response: 75–100 mg.


Instruction: What is a daily) versus an antiplatelet strategy Downloaded from http://ahajournals.org by on April 27, 2023

Output: 75–100 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a daily) versus an antiplatelet strategy Downloaded from http://ahajournals.org by on April 27, 2023. ### Response: 75–100 mg.


Instruction: What is the name of the velocardiofacial syndrome?

Output: DiGeorge syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the velocardiofacial syndrome?. ### Response: DiGeorge syndrome.


Instruction: What type of disease is IAA type B?

Output: psychiatric

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of disease is IAA type B?. ### Response: psychiatric.


Instruction: How much of the population has CHD?

Output: TOF25%–75%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the population has CHD?. ### Response: TOF25%–75%.


Instruction: What percentage of people have CHDKlinefelter syndrome 47 XXY Tall stature, hypoplastic testes, delayed puberty, developmental disabilityPDA, ASD, MV prolapse, developmental disability, characteristic facial features, hypotonia, palmar crease, AVSD, TOF?

Output: 75%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of people have CHDKlinefelter syndrome 47 XXY Tall stature, hypoplastic testes, delayed puberty, developmental disabilityPDA, ASD, MV prolapse, developmental disability, characteristic facial features, hypotonia, palmar crease, AVSD, TOF?. ### Response: 75%.


Instruction: What percentage of people have CHDNoonan syndrome?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of people have CHDNoonan syndrome?. ### Response: 50%.


Instruction: What percentage have CHDTurner syndrome 45X Short stature, webbed neck and lymphedema?

Output: 80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage have CHDTurner syndrome 45X Short stature, webbed neck and lymphedema?. ### Response: 80%.


Instruction: What percentage of patients with CHDRisk of aortic dissection have Wiliams syndrome 7q11.23 deletion Elfin face, social personality, hearing loss, developmental delay, infantile hypercalcemiaSupravalvar aartic stenosis, peripheral PS50%–80% have CHDASD indicates atrial septal defect?

Output: 30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with CHDRisk of aortic dissection have Wiliams syndrome 7q11.23 deletion Elfin face, social personality, hearing loss, developmental delay, infantile hypercalcemiaSupravalvar aartic stenosis, peripheral PS50%–80% have CHDASD indicates atrial septal defect?. ### Response: 30%.


Instruction: What does AVSD indicate?

Output: Developmental disability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AVSD indicate?. ### Response: Developmental disability.


Instruction: What is the acronym for congenital heart disease?

Output: CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for congenital heart disease?. ### Response: CHD.


Instruction: What is HCM?

Output: hypertrophic cardiomyopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HCM?. ### Response: hypertrophic cardiomyopathy.


Instruction: IAA stands for interrupted aortic arch, what is it?

Output: IAA type B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: IAA stands for interrupted aortic arch, what is it?. ### Response: IAA type B.


Instruction: PDA stands for patent ductus arteriosus, what does it mean?

Output: pulmonary stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PDA stands for patent ductus arteriosus, what does it mean?. ### Response: pulmonary stenosis.


Instruction: What is the recommended maintenance dose of aspirin to be used with ticagrelor?

Output: 81 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended maintenance dose of aspirin to be used with ticagrelor?. ### Response: 81 mg daily.


Instruction: What was observed irrespective of prior therapy with clopidogrel?

Output: Ticagrelor’s benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was observed irrespective of prior therapy with clopidogrel?. ### Response: Ticagrelor’s benefits.


Instruction: What may be especially important?

Output: Issues of patient compliance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be especially important?. ### Response: Issues of patient compliance.


Instruction: What should be given consideration to in patients with prior stroke or TIA?

Output: the potential and as yet undetermined risk of intracranial hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given consideration to in patients with prior stroke or TIA?. ### Response: the potential and as yet undetermined risk of intracranial hemorrhage.


Instruction: Patients weighing /H1102160 kg have an increased exposure to what?

Output: prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients weighing /H1102160 kg have an increased exposure to what?. ### Response: prasugrel.


Instruction: What is the active metabolite of prasugrel?

Output: /H1102160 kg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the active metabolite of prasugrel?. ### Response: /H1102160 kg.


Instruction: What is an increased risk of bleeding on a 10-mg once-daily maintenancedose?

Output: Patients weighing /H1102160 kg have an increased exposure to the active metabolite of prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increased risk of bleeding on a 10-mg once-daily maintenancedose?. ### Response: Patients weighing /H1102160 kg have an increased exposure to the active metabolite of prasugrel.


Instruction: How much maintenance dose should be considered in patients who weigh /H1102160 kg?

Output: 5 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much maintenance dose should be considered in patients who weigh /H1102160 kg?. ### Response: 5 mg.


Instruction: What has not been studied prospectively?

Output: the effectiveness and safety of the 5-mgdose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been studied prospectively?. ### Response: the effectiveness and safety of the 5-mgdose.


Instruction: What should be given for at least 12 mo for patients receiving DES?

Output: a daily maintenance dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given for at least 12 mo for patients receiving DES?. ### Response: a daily maintenance dose.


Instruction: How long should a daily maintenance dose be given to patients receiving BMS?

Output: up to12 mo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should a daily maintenance dose be given to patients receiving BMS?. ### Response: up to12 mo.


Instruction: The risk of bleeding outweighs the net benefit afforded by what?

Output: P2Y12receptor inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The risk of bleeding outweighs the net benefit afforded by what?. ### Response: P2Y12receptor inhibitor.


Instruction: What is the expected net benefit of a P2Y12receptor inhibitor?

Output: 2.0 to 2.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the expected net benefit of a P2Y12receptor inhibitor?. ### Response: 2.0 to 2.5.


Instruction: Do not use prasugrel inpatients with active pathological bleeding or a history of what?

Output: TIA or stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do not use prasugrel inpatients with active pathological bleeding or a history of what?. ### Response: TIA or stroke.


Instruction: What is generally not recommended in patients age /H1135075 y?

Output: prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is generally not recommended in patients age /H1135075 y?. ### Response: prasugrel.


Instruction: What is the risk of fatal and intracranial bleeding?

Output: increased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of fatal and intracranial bleeding?. ### Response: increased.


Instruction: What is prasugrel not used in in patients likely to undergo urgent CABG?

Output: active pathological bleeding or a history of TIA or stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is prasugrel not used in in patients likely to undergo urgent CABG?. ### Response: active pathological bleeding or a history of TIA or stroke.


Instruction: What is a risk factor for bleeding?

Output: body weight /H1102160 kg, propensity to bleed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for bleeding?. ### Response: body weight /H1102160 kg, propensity to bleed.


Instruction: What is an example of a medication that can increase the risk of bleed?

Output: prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a medication that can increase the risk of bleed?. ### Response: prasugrel.


Instruction: What is a risk of bleeding?

Output: propensity to bleed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk of bleeding?. ### Response: propensity to bleed.


Instruction: What is an INR of 2.0 to 2.5 preferable while given with aspirin?

Output: P2Y12receptor inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an INR of 2.0 to 2.5 preferable while given with aspirin?. ### Response: P2Y12receptor inhibitor.


Instruction: What is the INR for UA/NSTEMI patients with mechanical heart valves?

Output: 2.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the INR for UA/NSTEMI patients with mechanical heart valves?. ### Response: 2.5.


Instruction: What does BMS mean?

Output: bare-metal stent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does BMS mean?. ### Response: bare-metal stent.


Instruction: What does BMS stand for?

Output: bare-metal stent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does BMS stand for?. ### Response: bare-metal stent.


Instruction: What does CABG stand for??

Output: coronary artery bypass graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CABG stand for??. ### Response: coronary artery bypass graft.


Instruction: What is the acronym for drug-eluting stent?

Output: DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for drug-eluting stent?. ### Response: DES.


Instruction: What is a/non-ST-elevationmyocardial infarction?

Output: unstable angin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a/non-ST-elevationmyocardial infarction?. ### Response: unstable angin.


Instruction: What is the focus of the 2012 UA/NSTEMI Focused Update 891?

Output: unstable angin a/non–ST-elevationmyocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the 2012 UA/NSTEMI Focused Update 891?. ### Response: unstable angin a/non–ST-elevationmyocardial infarction.


Instruction: Hypertension and hypertension are associated with increased risk of CVD, ESRD, subclinical atherosclerosis, and all-cause death.

Output: e22  Hypertension  June 2018BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertension and hypertension are associated with increased risk of CVD, ESRD, subclinical atherosclerosis, and all-cause death.. ### Response: e22  Hypertension  June 2018BP.


Instruction: What is the recommended BP classification sys-tem most valuable in?

Output: untreated adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended BP classification sys-tem most valuable in?. ### Response: untreated adults.


Instruction: What is useful in assessing the success of interventions to reduce BP?

Output: The recommended BP classification sys-tem

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful in assessing the success of interventions to reduce BP?. ### Response: The recommended BP classification sys-tem.


Instruction: What have documented a relatively high inci-dence of hypertension over periods of 5 to 10 years of follow-up?

Output: Lifetime Risk of HypertensionObservational studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have documented a relatively high inci-dence of hypertension over periods of 5 to 10 years of follow-up?. ### Response: Lifetime Risk of HypertensionObservational studies.


Instruction: There is a much higher long-term population burden of what?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is a much higher long-term population burden of what?. ### Response: hypertension.


Instruction: What is the long-term population burden of hypertension?

Output: ≥20 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term population burden of hypertension?. ### Response: ≥20 years of age.


Instruction: What does BP progressively increase with age?

Output: long-term population burden of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does BP progressively increase with age?. ### Response: long-term population burden of hypertension.


Instruction: How many white male medical students were analyzed in the Johns Hopkins Precursors study?

Output: 1132

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many white male medical students were analyzed in the Johns Hopkins Precursors study?. ### Response: 1132.


Instruction: What percentage of the population developed hypertension at 25, 45, and 65 years in the Johns Hopkins Precursors study?

Output: 37%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the population developed hypertension at 25, 45, and 65 years in the Johns Hopkins Precursors study?. ### Response: 37%.


Instruction: In the MESA study, what race had a higher rate of developing hypertension than whites?

Output: Asians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the MESA study, what race had a higher rate of developing hypertension than whites?. ### Response: Asians.


Instruction: What was higher for African Americans and Hispanics than for whites and Asians?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was higher for African Americans and Hispanics than for whites and Asians?. ### Response: hypertension.


Instruction: For adults 45 years of age without hypertension, the 40-year risk of developing hypertension was 93% for what group?

Output: African-American

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For adults 45 years of age without hypertension, the 40-year risk of developing hypertension was 93% for what group?. ### Response: African-American.


Instruction: What percentage of adults in the Framingham Heart Study had hypertension?

Output: 46% versus 32%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of adults in the Framingham Heart Study had hypertension?. ### Response: 46% versus 32%)..


Instruction: In the Framingham Heart Study, what percentage of adults free of hypertension at age 55 or 65 years devel-oped hypertension during their lifetimes?

Output: 90%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the Framingham Heart Study, what percentage of adults free of hypertension at age 55 or 65 years devel-oped hypertension during their lifetimes?. ### Response: 90%.


Instruction: What cutpoint were all of these esti-mates based on?

Output: 140/90–mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What cutpoint were all of these esti-mates based on?. ### Response: 140/90–mm Hg.


Instruction: What would have been higher had the 130/80–mm Hg cutpoint been used?

Output: S3.2-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would have been higher had the 130/80–mm Hg cutpoint been used?. ### Response: S3.2-4.


Instruction: What is greatly influenced by the choice of cutpoints to categorize high BP?

Output: Prevalence estimates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is greatly influenced by the choice of cutpoints to categorize high BP?. ### Response: Prevalence estimates.


Instruction: How are most general population prevalence estimates derived?

Output: national surveys

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are most general population prevalence estimates derived?. ### Response: national surveys.


Instruction: What are the most general population prevalence estimates derived from?

Output: national surveys

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the most general population prevalence estimates derived from?. ### Response: national surveys.


Instruction: What table provides estimates for prevalence of hypertension in the US general adult population?

Output: Table 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What table provides estimates for prevalence of hypertension in the US general adult population?. ### Response: Table 7.


Instruction: What is the prevalence of hypertension among US adults when the definition in the present guideline is used versus the JNC 7 definition?

Output: 46% versus 32%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of hypertension among US adults when the definition in the present guideline is used versus the JNC 7 definition?. ### Response: 46% versus 32%)..


Instruction: What is nonpharmacological treatment recommended for most adults?

Output: not antihypertensive medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is nonpharmacological treatment recommended for most adults?. ### Response: not antihypertensive medication.


Instruction: What is recommended for most US adults who have hypertension as defined in the present guideline but would not meet the JNC 7 definition for hypertension?

Output: nonpharmacological treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for most US adults who have hypertension as defined in the present guideline but would not meet the JNC 7 definition for hypertension?. ### Response: nonpharmacological treatment.


Instruction: What does the new definition result in?

Output: only a small increase in the percentage of US adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the new definition result in?. ### Response: only a small increase in the percentage of US adults.


Instruction: What is recommended in conjunction with lifestyle modification?

Output: antihypertensive medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in conjunction with lifestyle modification?. ### Response: antihypertensive medication.


Instruction: What does the prevalence of hypertension rise with?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the prevalence of hypertension rise with?. ### Response: age.


Instruction: How many SRs, 6 RCTs, and 4 open-label extensions of RCT are there among patients at risk of CVD?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many SRs, 6 RCTs, and 4 open-label extensions of RCT are there among patients at risk of CVD?. ### Response: 25.


Instruction: What are some co -morbid conditions?

Output: diabetes, hypertension, CKD, CHF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some co -morbid conditions?. ### Response: diabetes, hypertension, CKD, CHF.


Instruction: What are some strategies used to improve patients’ tolerance to statins?

Output: education, swit ching statins, use of lower doses, alternate day dosing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some strategies used to improve patients’ tolerance to statins?. ### Response: education, swit ching statins, use of lower doses, alternate day dosing.


Instruction: What is an example of a strategy that can be used to help patients with CVD?

Output: education, swit ching statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a strategy that can be used to help patients with CVD?. ### Response: education, swit ching statins.


Instruction: How many cohort studies have been conducted?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cohort studies have been conducted?. ### Response: 4.


Instruction: What is the safety and efficacy of stopping statins for dyslipidemia among patients who have been on a statin?

Output: 2 SRs and 1 RCT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the safety and efficacy of stopping statins for dyslipidemia among patients who have been on a statin?. ### Response: 2 SRs and 1 RCT.


Instruction: How many SRs and 1 RCT 9 have you been on a statin?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many SRs and 1 RCT 9 have you been on a statin?. ### Response: 2.


Instruction: What is the cost-effectiveness of various pharmacologic (PCS K9 inhibitors, statins) and non-pharmacological treatments?

Output: 2 SRs and 3 cost -effectiveness studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of various pharmacologic (PCS K9 inhibitors, statins) and non-pharmacological treatments?. ### Response: 2 SRs and 3 cost -effectiveness studies.


Instruction: How many studies were performed in the setting of coronaryangiography?

Output: 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were performed in the setting of coronaryangiography?. ### Response: 8.


Instruction: What was the 95% confidence interval?

Output: 0.72 to 1.32

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 95% confidence interval?. ### Response: 0.72 to 1.32.


Instruction: What is performed in the setting of coronaryangiography?

Output: 8 studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed in the setting of coronaryangiography?. ### Response: 8 studies.


Instruction: What provides additional supportive evidence?

Output: A more recent study comparing iodixanolversus iopamidol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides additional supportive evidence?. ### Response: A more recent study comparing iodixanolversus iopamidol.


Instruction: The relative paucity of head-to-head trials comparing CINrates among the various contrast media must be tempered by what?

Output: variability inresults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The relative paucity of head-to-head trials comparing CINrates among the various contrast media must be tempered by what?. ### Response: variability inresults.


Instruction: What is a reliable predictor of the more serious development of renal failure requiring hospitalization or dialysis?

Output: transient risein serum creatinine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reliable predictor of the more serious development of renal failure requiring hospitalization or dialysis?. ### Response: transient risein serum creatinine.


Instruction: What was a nationwide Swedish survey181of hospitaliza-tions for renal failure after coronary heart disease?

Output: iodixanol (1.7%) than ioxaglate (0.8%) or iohexol (0.9%;P/H110210.001). Although the result was observational, hencesubject to selection bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a nationwide Swedish survey181of hospitaliza-tions for renal failure after coronary heart disease?. ### Response: iodixanol (1.7%) than ioxaglate (0.8%) or iohexol (0.9%;P/H110210.001). Although the result was observational, hencesubject to selection bias.


Instruction: How many patients were hospitalized for renal failure after coronary procedures in Sweden?

Output: 57 925

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were hospitalized for renal failure after coronary procedures in Sweden?. ### Response: 57 925.


Instruction: What was the risk of renal failure higher with iodixanol?

Output: 1.7%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of renal failure higher with iodixanol?. ### Response: 1.7%).


Instruction: Ioxaglate had a risk of what?

Output: 0.8%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ioxaglate had a risk of what?. ### Response: 0.8%).


Instruction: What is a high-riskpatient subset?

Output: patients with diabetes, prior history of renalfailure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a high-riskpatient subset?. ### Response: patients with diabetes, prior history of renalfailure.


Instruction: What was speculated but not demonstrated as a possible mech-anism for the observed effect?

Output: Iodixanol’s greater viscosity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was speculated but not demonstrated as a possible mech-anism for the observed effect?. ### Response: Iodixanol’s greater viscosity.


Instruction: What is not sufficient to enable a guidelinestatement on selection among commonly used low-osmolar media?

Output: strength and consistency of relation-ships between specific isosmolar or low-osmolar agents andCIN or renal failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not sufficient to enable a guidelinestatement on selection among commonly used low-osmolar media?. ### Response: strength and consistency of relation-ships between specific isosmolar or low-osmolar agents andCIN or renal failure.


Instruction: What does the writing group recommend focusing on?

Output: operator conduct issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing group recommend focusing on?. ### Response: operator conduct issues.


Instruction: What does the writing group recommend focusing on instead of isosmolar media?

Output: operator conduct issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing group recommend focusing on instead of isosmolar media?. ### Response: operator conduct issues.


Instruction: What is shown to be important toprotect patients?

Output: operator conduct issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shown to be important toprotect patients?. ### Response: operator conduct issues.


Instruction: The writing group re-viewed several trials regarding what?

Output: optimal preparatory regimenof hydration and pharmacotherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The writing group re-viewed several trials regarding what?. ### Response: optimal preparatory regimenof hydration and pharmacotherapy.


Instruction: What did the writing group re-view?

Output: several trials addressing the optimal preparatory regimenof hydration and pharmacotherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing group re-view?. ### Response: several trials addressing the optimal preparatory regimenof hydration and pharmacotherapy.


Instruction: What is the basic principle ofhydration?

Output: experimental studies and clinical expe-rience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the basic principle ofhydration?. ### Response: experimental studies and clinical expe-rience.


Instruction: Isotonic or half-normal saline alone are the historical gold standards?

Output: hydration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Isotonic or half-normal saline alone are the historical gold standards?. ### Response: hydration.


Instruction: What has been tested as the hydrating solution?

Output: sodiumbicarbonate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been tested as the hydrating solution?. ### Response: sodiumbicarbonate.


Instruction: Some trials have reported superiority of sodium bicarbonate over saline inpreventing what?

Output: CIN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some trials have reported superiority of sodium bicarbonate over saline inpreventing what?. ### Response: CIN.


Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3831 891.

Output: Aspirin for Asymptomatic Atherosclerosis Trialists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3831 891.. ### Response: Aspirin for Asymptomatic Atherosclerosis Trialists.


Instruction: Fowkes FG, Price JF, Stewart MC, Leng GC, Pell AC, Sandercock PA, Lowe GD, Murray GD; Aspirin for Asymptomatic Atherosclerosis Trialists.

Output: Meschia et al  Guidelines for the Primary Prevention of Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fowkes FG, Price JF, Stewart MC, Leng GC, Pell AC, Sandercock PA, Lowe GD, Murray GD; Aspirin for Asymptomatic Atherosclerosis Trialists.. ### Response: Meschia et al  Guidelines for the Primary Prevention of Stroke.


Instruction: What is cilostazol used for in patients with atherothrombosis?

Output: Stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cilostazol used for in patients with atherothrombosis?. ### Response: Stroke prevention.


Instruction: What is the name of the randomized controlled trial?

Output: Aspirin for Asymptomatic Atherosclerosis Trialists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial?. ### Response: Aspirin for Asymptomatic Atherosclerosis Trialists.


Instruction: What is the benefit of aspirin in hypertensive patients with chronic kidney disease?

Output: Aspirin is beneficial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of aspirin in hypertensive patients with chronic kidney disease?. ### Response: Aspirin is beneficial.


Instruction: What is aspirin beneficial for in hypertensive patients with chronic kidney disease?

Output: Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aspirin beneficial for in hypertensive patients with chronic kidney disease?. ### Response: Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trial.


Instruction: What is a post-hoc subgroup analysis of a randomized controlled trial?

Output: Aspirin is beneficial in hypertensive patients with chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a post-hoc subgroup analysis of a randomized controlled trial?. ### Response: Aspirin is beneficial in hypertensive patients with chronic kidney disease.


Instruction: When was J Am Coll Cardiol.56:956-965?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was J Am Coll Cardiol.56:956-965?. ### Response: 2010.


Instruction: How old are adults aged 18 and over in the United States?

Output: 1997–2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are adults aged 18 and over in the United States?. ### Response: 1997–2011.


Instruction: When was the year 1997-2011 selected?

Output: United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the year 1997-2011 selected?. ### Response: United States.


Instruction: What year was the 2011/094.pdf Accessed March 14, 2013?

Output: 1997–2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the 2011/094.pdf Accessed March 14, 2013?. ### Response: 1997–2011.


Instruction: Who is Babcock Irvin?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Babcock Irvin?. ### Response: C.


Instruction: What is the purpose of the Society for Academic Emergency Medicine Public Health and Education Task Force Preventive Services Work Group?

Output: Preventive care in the emer -gency department, part II: clinical preventive services: an emergency medicine evidence-based review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of the Society for Academic Emergency Medicine Public Health and Education Task Force Preventive Services Work Group?. ### Response: Preventive care in the emer -gency department, part II: clinical preventive services: an emergency medicine evidence-based review.


Instruction: What is a critical juxtaposition of public health, prevention, and emergency medicine?

Output: Bernstein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a critical juxtaposition of public health, prevention, and emergency medicine?. ### Response: Bernstein.


Instruction: What is the Acad Emerg Med. 2008?

Output: 15:190–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Acad Emerg Med. 2008?. ### Response: 15:190–.


Instruction: How many stroke risk factors and warning signs are there among Michigan adults?

Output: 899

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many stroke risk factors and warning signs are there among Michigan adults?. ### Response: 899.


Instruction: What year did Neurology publish a 59:1547–1552. 899. Marsden C, Pinell MC, Joyce SM. Emergency physicians and preventive medicine. West J Med. 1988;149:345. 800. Delgado MK, Acosta CD, Ginde AA, Wang NE, Strehlow MC and Camargo CA Jr. National survey of preventive health services in US emergency departments. 2011;57:104–108.e2. 901.

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Neurology publish a 59:1547–1552. 899. Marsden C, Pinell MC, Joyce SM. Emergency physicians and preventive medicine. West J Med. 1988;149:345. 800. Delgado MK, Acosta CD, Ginde AA, Wang NE, Strehlow MC and Camargo CA Jr. National survey of preventive health services in US emergency departments. 2011;57:104–108.e2. 901.. ### Response: 2002.


Instruction: What is asymptomatic severe blood pressure elevation in the emergency department?

Output: routine testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic severe blood pressure elevation in the emergency department?. ### Response: routine testing.


Instruction: What is an example of a routine blood pressure test?

Output: asymptom-atic severe blood pressure elevation in the emergency department

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a routine blood pressure test?. ### Response: asymptom-atic severe blood pressure elevation in the emergency department.


Instruction: In what year did Ann Emerg Med publish a report on the utility of routine testing?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Ann Emerg Med publish a report on the utility of routine testing?. ### Response: 2008.


Instruction: What type of heart disease is found in black patients with elevated blood pressure in an inner-city emergency department?

Output: Subclinical hypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart disease is found in black patients with elevated blood pressure in an inner-city emergency department?. ### Response: Subclinical hypertensive.


Instruction: In what year did Ann Emerg Med issue 60:467-474?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Ann Emerg Med issue 60:467-474?. ### Response: 2012.


Instruction: What year was Kidney International founded?

Output: 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Kidney International founded?. ### Response: 2021.


Instruction: What is the name of the organization that was founded in 2021?

Output: Kidney International

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that was founded in 2021?. ### Response: Kidney International.


Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e93?

Output: S8.1.5-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e93?. ### Response: S8.1.5-5.


Instruction: What is Bundy JD, Li C, Stuchlik P, et al. Systolic blood pressure reduction and risk of cardiovascular disease and mortality?

Output: a systematic review and network meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Bundy JD, Li C, Stuchlik P, et al. Systolic blood pressure reduction and risk of cardiovascular disease and mortality?. ### Response: a systematic review and network meta-analysis.


Instruction: What is an angiotensin-receptor blocker used for?

Output: treating pre-hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an angiotensin-receptor blocker used for?. ### Response: treating pre-hypertension.


Instruction: What is a review of the evidence on blood pressure and coronary heart disease?

Output: Systematic review for the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a review of the evidence on blood pressure and coronary heart disease?. ### Response: Systematic review for the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Instruction: What is the final result of the treatment of mild hypertension study?

Output: S8.1.5-10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the final result of the treatment of mild hypertension study?. ### Response: S8.1.5-10.


Instruction: What was the name of the study that showed the final results?

Output: Treatment of Mild Hypertension Study Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that showed the final results?. ### Response: Treatment of Mild Hypertension Study Research Group.


Instruction: What are the final results of the Treatment of Mild Hypertension Study?

Output: S8.1.5-10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the final results of the Treatment of Mild Hypertension Study?. ### Response: S8.1.5-10.


Instruction: What is the name of the study?

Output: Mild Hypertension Study Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: Mild Hypertension Study Research Group.


Instruction: When was the JAMA 270:713–24?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA 270:713–24?. ### Response: 1993.


Instruction: What does the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines focus on?

Output: prevention, detection, evaluation, and management of high blood pressure in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines focus on?. ### Response: prevention, detection, evaluation, and management of high blood pressure in adults.


Instruction: What does Brunstrom M, Carlberg B say about antihypertensive treatment in diabetes mellitus?

Output: Effect of antihypertensive treatment at different blood pressure levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Brunstrom M, Carlberg B say about antihypertensive treatment in diabetes mellitus?. ### Response: Effect of antihypertensive treatment at different blood pressure levels.


Instruction: What is the name of the systematic review and meta-analyses of patients with diabetes mellitus?

Output: Brunstrom M, Carlberg B. Effect of antihypertensive treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analyses of patients with diabetes mellitus?. ### Response: Brunstrom M, Carlberg B. Effect of antihypertensive treatment.


Instruction: What is a systematic review of blood pressure lowering for prevention of cardiovascular disease and death?

Output: meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of blood pressure lowering for prevention of cardiovascular disease and death?. ### Response: meta-analysis.


Instruction: What does intensive blood pressure lowering do to the progression of chronic kidney disease?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does intensive blood pressure lowering do to the progression of chronic kidney disease?. ### Response: Effects.


Instruction: What is the name of the study that examined the effects of inten-sive blood pressure control in type 2 diabetes mellitus?

Output: ACCORD Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the effects of inten-sive blood pressure control in type 2 diabetes mellitus?. ### Response: ACCORD Study.


Instruction: What is type 2 diabetes mellitus?

Output: Effects of inten-sive blood-pressure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is type 2 diabetes mellitus?. ### Response: Effects of inten-sive blood-pressure control.


Instruction: What is the name of the randomized trial of intensive versus standard blood-pressure control?

Output: SPRINT Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of intensive versus standard blood-pressure control?. ### Response: SPRINT Research Group.


Instruction: When was the ACCORD Study conducted?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ACCORD Study conducted?. ### Response: 2010.


Instruction: What is the name of the randomised trial that found blood pressure targets in lacunar stroke patients?

Output: SPS3 Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial that found blood pressure targets in lacunar stroke patients?. ### Response: SPS3 Study Group.