Instruction: How much sensitivity does native valve endocarditis have?

Output: 90% to 100%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much sensitivity does native valve endocarditis have?. ### Response: 90% to 100%,.


Instruction: What is TTE able to detect and quantify?

Output: valve dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TTE able to detect and quantify?. ### Response: valve dysfunction.


Instruction: What may provide impor-tant evidence for a paravalvular leak?

Output: a proximal convergence zone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may provide impor-tant evidence for a paravalvular leak?. ### Response: a proximal convergence zone.


Instruction: What does TTE exhibit superior imaging over TEE for?

Output: the anterior aspect of a prosthetic aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does TTE exhibit superior imaging over TEE for?. ### Response: the anterior aspect of a prosthetic aortic valve.


Instruction: What is commonly shadowed by the valve on TEE?

Output: prosthetic aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is commonly shadowed by the valve on TEE?. ### Response: prosthetic aortic valve.


Instruction: What allows measurement of aortic transvalvular velocity/gradient?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What allows measurement of aortic transvalvular velocity/gradient?. ### Response: TTE.


Instruction: TTE will not definitively exclude what in IE?

Output: veg-etations or abscesses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: TTE will not definitively exclude what in IE?. ### Response: veg-etations or abscesses.


Instruction: What is the sensitivity of TEE in native valve endocarditis?

Output: 90% to 100%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sensitivity of TEE in native valve endocarditis?. ### Response: 90% to 100%,.


Instruction: What is TEE superior to in the visualization of both veg-etations?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TEE superior to in the visualization of both veg-etations?. ### Response: TTE.


Instruction: What is superior to TEE in the visualization of both veg-etations and paravalvular complications?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is superior to TEE in the visualization of both veg-etations and paravalvular complications?. ### Response: TEE.


Instruction: What can be anatomic (eg, valve perforation, abscesses, and pericardial effusion) or hemodynamic in nature?

Output: paravalvular complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be anatomic (eg, valve perforation, abscesses, and pericardial effusion) or hemodynamic in nature?. ### Response: paravalvular complications.


Instruction: What should be used as an adjunct in patients with echocardiographic features of IE on TTE to rule out the presence of findings such as abscesses?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used as an adjunct in patients with echocardiographic features of IE on TTE to rule out the presence of findings such as abscesses?. ### Response: TEE.


Instruction: What may alter the therapeutic approach to the management of the patient?

Output: abscesses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may alter the therapeutic approach to the management of the patient?. ### Response: abscesses.


Instruction: What does TEE serve a vital role in reassessment of patients with known IE with suspected clinical complica-tions?

Output: a guiding tool in the intraoperative assessment and management of the patient with IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does TEE serve a vital role in reassessment of patients with known IE with suspected clinical complica-tions?. ### Response: a guiding tool in the intraoperative assessment and management of the patient with IE.


Instruction: What is TEE a guiding tool in the intraoperative assessment and management of the patient with IE?

Output: early treatment decisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TEE a guiding tool in the intraoperative assessment and management of the patient with IE?. ### Response: early treatment decisions.


Instruction: What depends on the clinical presentation and course and on the virulence of the microorganism?

Output: The timing of repeat examinations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What depends on the clinical presentation and course and on the virulence of the microorganism?. ### Response: The timing of repeat examinations.


Instruction: Increasing vegetation size under therapy must be considered what?

Output: a risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Increasing vegetation size under therapy must be considered what?. ### Response: a risk.


Instruction: What is the 2015 ACC/AHA/HRS SVT Guideline e525Verapamil 5-10-mg?

Output: IV bolus over 2 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2015 ACC/AHA/HRS SVT Guideline e525Verapamil 5-10-mg?. ### Response: IV bolus over 2 min.


Instruction: How long after first dose can you give an additional 10 mg (0.15 mg/kg)?

Output: 30 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after first dose can you give an additional 10 mg (0.15 mg/kg)?. ### Response: 30 min.


Instruction: What is worsening in patients with pre-existing ventricular dysfunction?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is worsening in patients with pre-existing ventricular dysfunction?. ### Response: HF.


Instruction: What is a moderate CYP3A4 inhibitor and also inhibits P-glycoprotein?

Output: Verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a moderate CYP3A4 inhibitor and also inhibits P-glycoprotein?. ### Response: Verapamil.


Instruction: Verapamil is contraindicated with what?

Output: dofetilide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Verapamil is contraindicated with what?. ### Response: dofetilide.


Instruction: What is the maximum dose of digoxin over 24 h?

Output: 1.0 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum dose of digoxin over 24 h?. ### Response: 1.0 mg.


Instruction: How long does the IV bolus last?

Output: 24 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does the IV bolus last?. ### Response: 24 h.


Instruction: What are some symptoms of digoxin toxicity?

Output: lower levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some symptoms of digoxin toxicity?. ### Response: lower levels.


Instruction: What is a P-glycoprotein substrate of digoxin?

Output: Dronedarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a P-glycoprotein substrate of digoxin?. ### Response: Dronedarone.


Instruction: How much do drugs with AV nodal-blocking properties reduce their dose?

Output: 50%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much do drugs with AV nodal-blocking properties reduce their dose?. ### Response: 50%),.


Instruction: What does amiodarone reduce their dosage by?

Output: 30%–50%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does amiodarone reduce their dosage by?. ### Response: 30%–50%).


Instruction: Digoxin is associated with what?

Output: levels >2 ng/mL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Digoxin is associated with what?. ### Response: levels >2 ng/mL.


Instruction: Who was treated with digoxin for newly diagnosed AF or atrial flutter?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was treated with digoxin for newly diagnosed AF or atrial flutter?. ### Response: patients.


Instruction: Digoxin should be used with what caution?

Output: caution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Digoxin should be used with what caution?. ### Response: caution.


Instruction: What is the class of antiarrhythmic agents?

Output: Class III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of antiarrhythmic agents?. ### Response: Class III.


Instruction: What is a substrate for and inhibits p-glycoprotein and CYP2C9 (moderate)?

Output: Amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a substrate for and inhibits p-glycoprotein and CYP2C9 (moderate)?. ### Response: Amiodarone.


Instruction: How long does it take to infuse amiodarone over 10 min?

Output: 30 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to infuse amiodarone over 10 min?. ### Response: 30 min.


Instruction: What is rare in AV conduction disease?

Output: torsades de pointes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rare in AV conduction disease?. ### Response: torsades de pointes.


Instruction: What is a substrate for CYP3A4?

Output: amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a substrate for CYP3A4?. ### Response: amiodarone.


Instruction: What is an inhibitor of OCT2?

Output: amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an inhibitor of OCT2?. ### Response: amiodarone.


Instruction: What is strated in important subgroups not represented in theP A R A D I G M - H Ft r i a l,su c ha st h o s ew i to hd en oV oH Fo rn ai v et oA C E I s?

Output: s u c ha st h o s ew i t hd en o v oH Fo rn a i v et oA C E I s / A R B s ,t h o s ew i t hl o w e re n r o l l m e n tN - t e r -minal pro –B-type natriuretic peptide (NT-proBNP) con-centrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is strated in important subgroups not represented in theP A R A D I G M - H Ft r i a l,su c ha st h o s ew i to hd en oV oH Fo rn ai v et oA C E I s?. ### Response: s u c ha st h o s ew i t hd en o v oH Fo rn a i v et oA C E I s / A R B s ,t h o s ew i t hl o w e re n r o l l m e n tN - t e r -minal pro –B-type natriuretic peptide (NT-proBNP) con-centrations.


Instruction: What does NT-proBNP stand for?

Output: pro –B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NT-proBNP stand for?. ### Response: pro –B-type natriuretic peptide.


Instruction: What is the name of the peptide that is not able to be used in concentration?

Output: NT-proBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the peptide that is not able to be used in concentration?. ### Response: NT-proBNP.


Instruction: What is the name of the randomizedEVALUATE-HF trial?

Output: PROVE-HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomizedEVALUATE-HF trial?. ### Response: PROVE-HF.


Instruction: What did the Mild to Moderate HF With Reduced Ejection Fraction) trial show?

Output: an improvement in echocardiographic pa-rameters of reverse cardiac remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Mild to Moderate HF With Reduced Ejection Fraction) trial show?. ### Response: an improvement in echocardiographic pa-rameters of reverse cardiac remodeling.


Instruction: How early did the trial show improvement in echocardiographic pa-rameters of reverse cardiac remodeling?

Output: 12weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How early did the trial show improvement in echocardiographic pa-rameters of reverse cardiac remodeling?. ### Response: 12weeks.


Instruction: What was the duration of the trial with enalapril?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the duration of the trial with enalapril?. ### Response: 20.


Instruction: Is an aldosterone antagonist mandatory before ARNItherapy?

Output: not required

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is an aldosterone antagonist mandatory before ARNItherapy?. ### Response: not required.


Instruction: Is there any existing predicate data to suggest thatan aldosterone antagonist is mandatory?

Output: no

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is there any existing predicate data to suggest thatan aldosterone antagonist is mandatory?. ### Response: no.


Instruction: What should not delay initiating or switching a patient to anA R N I.G u i d a n c ef o rt?

Output: lack of treatment with an aldosterone antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not delay initiating or switching a patient to anA R N I.G u i d a n c ef o rt?. ### Response: lack of treatment with an aldosterone antagonists.


Instruction: What is detailed in Figures 2 and 3 and in Tables 1 to 4?

Output: ARNI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is detailed in Figures 2 and 3 and in Tables 1 to 4?. ### Response: ARNI.


Instruction: How long should a washout period be strictly observed to avoid angioedema?

Output: 36-hour

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should a washout period be strictly observed to avoid angioedema?. ### Response: 36-hour.


Instruction: What should be strictly observed to avoid angioedema?

Output: a36-hour washout period

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be strictly observed to avoid angioedema?. ### Response: a36-hour washout period.


Instruction: What is not required when switching from an ARB to an ARNI?

Output: angioedema

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not required when switching from an ARB to an ARNI?. ### Response: angioedema.


Instruction: How long did the investigators compare titration to a targetdose?

Output: between 3 and 6 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the investigators compare titration to a targetdose?. ### Response: between 3 and 6 weeks.


Instruction: How long did titration take to reach the target dose of sacubitril/valsartan?

Output: 3 and 6 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did titration take to reach the target dose of sacubitril/valsartan?. ### Response: 3 and 6 weeks.


Instruction: What did the gradual titration approach achieve in patients previously receiving low doses of anACEI/ARB?

Output: attainment of the target dose of sacubitril/valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the gradual titration approach achieve in patients previously receiving low doses of anACEI/ARB?. ### Response: attainment of the target dose of sacubitril/valsartan.


Instruction: What is the maximum tolerated dose of beta-blocker?

Output: $70 beats/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum tolerated dose of beta-blocker?. ### Response: $70 beats/min.


Instruction: IvabradinenHFrEF (EF #35%) is used in place of an ACEI or what?

Output: ARBI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: IvabradinenHFrEF (EF #35%) is used in place of an ACEI or what?. ### Response: ARBI.


Instruction: What is the EF of SGLT2 Inhibitor?

Output: #40%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the EF of SGLT2 Inhibitor?. ### Response: #40%).


Instruction: What is a background of GDMT for?

Output: HFACEI¼angiotensin-converting-enzyme inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a background of GDMT for?. ### Response: HFACEI¼angiotensin-converting-enzyme inhibitor.


Instruction: What is the name of the blocker that blocks angiotensin receptor-neprilysin?

Output: ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the blocker that blocks angiotensin receptor-neprilysin?. ### Response: ARB.


Instruction: What is EF 14ejection fraction?

Output: ¼

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EF 14ejection fraction?. ### Response: ¼.


Instruction: What year did the ECDP for Optimization of Heart Failure Treatment come into effect?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the ECDP for Optimization of Heart Failure Treatment come into effect?. ### Response: 2017.


Instruction: How are patients treated after the last subcuta-neous dose?

Output: full-dose de novoanticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are patients treated after the last subcuta-neous dose?. ### Response: full-dose de novoanticoagulation.


Instruction: What is a full-dose de novoanticoagulation regimen?

Output: full-doseUFH or bivalirudin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a full-dose de novoanticoagulation regimen?. ### Response: full-doseUFH or bivalirudin.


Instruction: How is bivalirudin useful for patients undergoing PCI?

Output: asan anticoagulant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is bivalirudin useful for patients undergoing PCI?. ### Response: asan anticoagulant.


Instruction: What type of anticoagulant with or without prior treatment?

Output: bivalirudin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of anticoagulant with or without prior treatment?. ### Response: bivalirudin.


Instruction: What is the level of evidence for the use of UFH?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for the use of UFH?. ### Response: B.


Instruction: How many U/kg bolus is planned to achieve an ACT of 200 to 250 s?

Output: 50 to 70

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many U/kg bolus is planned to achieve an ACT of 200 to 250 s?. ### Response: 50 to 70.


Instruction: What is the IV GPI planned for?

Output: 50 to 70 U/kg bolus to achieve anACT of 200 to 250 s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the IV GPI planned for?. ### Response: 50 to 70 U/kg bolus to achieve anACT of 200 to 250 s.


Instruction: How much UFH is needed to achieve the ACT for HemoTec?

Output: 250 to 300 s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much UFH is needed to achieve the ACT for HemoTec?. ### Response: 250 to 300 s.


Instruction: How long is the ACT for HemoTec?

Output: 250 to 300 s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the ACT for HemoTec?. ### Response: 250 to 300 s.


Instruction: How long does it take forHemochron to achievetarget ACT of 250 to 300 s?

Output: 300 to 350 s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take forHemochron to achievetarget ACT of 250 to 300 s?. ### Response: 300 to 350 s.


Instruction: What is the maximum ACT in s forhemotec?

Output: 250 to 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum ACT in s forhemotec?. ### Response: 250 to 300.


Instruction: For prior treatment with enoxaparin, how many times was the last dose given?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For prior treatment with enoxaparin, how many times was the last dose given?. ### Response: 1.


Instruction: What should be given if the last SC dose was administered 8 to 12 h earlier or if only 1 SC dose of enoxaparin has been administered?

Output: an IV dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given if the last SC dose was administered 8 to 12 h earlier or if only 1 SC dose of enoxaparin has been administered?. ### Response: an IV dose.


Instruction: What should not be given if the dose was administered within the prior 8 h?

Output: additional enoxaparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be given if the dose was administered within the prior 8 h?. ### Response: additional enoxaparin.


Instruction: For patients who have received UFH, wait 30 min, then give 0.75 mg/kgIV bolus, then what?

Output: 1.75 mg/kg per h IV infusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients who have received UFH, wait 30 min, then give 0.75 mg/kgIV bolus, then what?. ### Response: 1.75 mg/kg per h IV infusion.


Instruction: What should be given for prior treatment with fondaparinux?

Output: administer additional IV treatmentwith an anticoagulant possessing anti-IIa activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given for prior treatment with fondaparinux?. ### Response: administer additional IV treatmentwith an anticoagulant possessing anti-IIa activity.


Instruction: What anticoagulant can be used for prior treatment with fondaparinux?

Output: anti

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What anticoagulant can be used for prior treatment with fondaparinux?. ### Response: anti.


Instruction: What is an indication of activated clotting time?

Output: IVinfusionACT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an indication of activated clotting time?. ### Response: IVinfusionACT.


Instruction: How many mg/kg per min IVinfusionACT indicates activated clotting time?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg/kg per min IVinfusionACT indicates activated clotting time?. ### Response: 25.


Instruction: What is IV, intravenous; GPI, glycoprotein inhibitor; N/A, not applicable; PCI, percutaneous coronary interventi on; and SC, unfractionated heparin?

Output: IV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is IV, intravenous; GPI, glycoprotein inhibitor; N/A, not applicable; PCI, percutaneous coronary interventi on; and SC, unfractionated heparin?. ### Response: IV.


Instruction: What are some examples of change?

Output: gr oup w ork f or motiv ating lif estyle change

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some examples of change?. ### Response: gr oup w ork f or motiv ating lif estyle change.


Instruction: What is a good explanation of what the committee did?

Output: delet ed the recommendation on relaxation t herapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a good explanation of what the committee did?. ### Response: delet ed the recommendation on relaxation t herapies.


Instruction: What is t he rationale and impact section on r elaxation t herapies?

Output: Notice of right s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he rationale and impact section on r elaxation t herapies?. ### Response: Notice of right s.


Instruction: Full details of evidence and committee's discussion ar e in evidence?

Output: 4.9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Full details of evidence and committee's discussion ar e in evidence?. ### Response: 4.9.


Instruction: Starting an tihyper tensi ve drug tr eatmen might aff ect what?

Output: practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Starting an tihyper tensi ve drug tr eatmen might aff ect what?. ### Response: practice.


Instruction: NICE has created a patient decision aid on what to help people and their healt hcare professionals discuss t he diff erent types of tr eatment?

Output: tr eatment options f or hyper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: NICE has created a patient decision aid on what to help people and their healt hcare professionals discuss t he diff erent types of tr eatment?. ### Response: tr eatment options f or hyper tension.


Instruction: What is NICE's guideline on medicines optimisation?

Output: patient decision aids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE's guideline on medicines optimisation?. ### Response: patient decision aids.


Instruction: What is NICE's guideline on medicines adherence?

Output: multimorbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE's guideline on medicines adherence?. ### Response: multimorbidity.


Instruction: What do people with hyper tension need to know about their medicines?

Output: the most eff ectiv e use of t heir medicines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do people with hyper tension need to know about their medicines?. ### Response: the most eff ectiv e use of t heir medicines.


Instruction: Antih yper tensiv e drug tr eatment in addition to lifestyle advice t o adult s of an y age wit h persist ent stage 2 hyper tension?

Output: 4.9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antih yper tensiv e drug tr eatment in addition to lifestyle advice t o adult s of an y age wit h persist ent stage 2 hyper tension?. ### Response: 4.9.


Instruction: Use clinical judgement f or people of what age?

Output: an y age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Use clinical judgement f or people of what age?. ### Response: an y age.


Instruction: See also NICE's guideline for people with frailty or multimorbidity?

Output: 4.9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: See also NICE's guideline for people with frailty or multimorbidity?. ### Response: 4.9.


Instruction: What is NICE's guideline on multimorbidity?

Output: Use clinical judgement f or people of an y age wit h frailty or multimorbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE's guideline on multimorbidity?. ### Response: Use clinical judgement f or people of an y age wit h frailty or multimorbidity.


Instruction: What do adults under 80 wit h persist ent stage 1 hyper tension?

Output: target or gan damage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do adults under 80 wit h persist ent stage 1 hyper tension?. ### Response: target or gan damage.


Instruction: Who has 1 or mor e of t he following: • target or gan damage • established car diovascular disease • renal disease • diabet es Hyper tension in adult s: diagnosis and management (NG136)?

Output: adult s aged under  80 wit h persist ent stage  1 hyper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has 1 or mor e of t he following: • target or gan damage • established car diovascular disease • renal disease • diabet es Hyper tension in adult s: diagnosis and management (NG136)?. ### Response: adult s aged under  80 wit h persist ent stage  1 hyper tension.


Instruction: What is NICE 2023?

Output: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2023?. ### Response: diagnosis and management.


Instruction: When was the last updat ed?

Output: 18 Mar ch 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed?. ### Response: 18 Mar ch 2022.


Instruction: What should not be used to improve morbidity and mortality in patients with HF and anemia?

Output: erythropoietin-stimulating agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be used to improve morbidity and mortality in patients with HF and anemia?. ### Response: erythropoietin-stimulating agents.


Instruction: What does the current recommendation reflect?

Output: new evidence demonstrating absence of therapeutic benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the current recommendation reflect?. ### Response: new evidence demonstrating absence of therapeutic benefit.


Instruction: How many RCTs did a meta-analysis of?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs did a meta-analysis of?. ### Response: 11.


Instruction: What has been suggested to improve functional capacity and reduce hospitalization in patients with HF?

Output: erythropoietin-stimulating agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been suggested to improve functional capacity and reduce hospitalization in patients with HF?. ### Response: erythropoietin-stimulating agents.


Instruction: What is STAMINA-HeFT?

Output: Study of Anemia in Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is STAMINA-HeFT?. ### Response: Study of Anemia in Heart Failure.


Instruction: How many RCTs were there?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs were there?. ### Response: 11.


Instruction: What were the results of the meta-analysis?

Output: significant improvements in 6-minute walk, exercise duration, peak Vo2, NYHA functional status, EF, BNP , HF-related hospitalizations, and QoL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the results of the meta-analysis?. ### Response: significant improvements in 6-minute walk, exercise duration, peak Vo2, NYHA functional status, EF, BNP , HF-related hospitalizations, and QoL.


Instruction: What was not associated with significant clinical benefits?

Output: darbepoetin alfa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not associated with significant clinical benefits?. ### Response: darbepoetin alfa.


Instruction: In the largest RCT to date, what did darbopoetin alfa not result in?

Output: benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the largest RCT to date, what did darbopoetin alfa not result in?. ### Response: benefit.


Instruction: What is the strongest evidence on erythropoietin-stimulating agent therapy in HF?

Output: lack of benefit and increased adverse events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strongest evidence on erythropoietin-stimulating agent therapy in HF?. ### Response: lack of benefit and increased adverse events.


Instruction: What is erythropoietin-stimulating agent therapy not recommended for in patients with HF and anemia?

Output: improve morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is erythropoietin-stimulating agent therapy not recommended for in patients with HF and anemia?. ### Response: improve morbidity and mortality.


Instruction: What is the initial daily dose of ACE inhibitors Captopril 6.25 mg TID?

Output: 50 mg TID 122.7 mg QD 158

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the initial daily dose of ACE inhibitors Captopril 6.25 mg TID?. ### Response: 50 mg TID 122.7 mg QD 158.


Instruction: How many mg QD 158 Enalapril 2.5 mg?

Output: 122.7 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg QD 158 Enalapril 2.5 mg?. ### Response: 122.7 mg.


Instruction: How much TID does Enalapril have?

Output: 2.5 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much TID does Enalapril have?. ### Response: 2.5 mg.


Instruction: How many mg QD does Lisinopril contain?

Output: 2.5–5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg QD does Lisinopril contain?. ### Response: 2.5–5.


Instruction: What is the dosage range of Enalpril?

Output: 2.5 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the dosage range of Enalpril?. ### Response: 2.5 mg.


Instruction: Which drug has the highest TID?

Output: Captopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug has the highest TID?. ### Response: Captopril.


Instruction: What is Quinapril 5 mg BID 20 mg N/A?

Output: Ramipril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Quinapril 5 mg BID 20 mg N/A?. ### Response: Ramipril.


Instruction: What is Ramipril 1.25-2.5 mg QD 10 mg?

Output: Quinapril 5 mg BID 20 mg BID N/A — Ramipril 1.25–2.5 mg QD 10 mg QD N/A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Ramipril 1.25-2.5 mg QD 10 mg?. ### Response: Quinapril 5 mg BID 20 mg BID N/A — Ramipril 1.25–2.5 mg QD 10 mg QD N/A.


Instruction: How much QD does Candesartan have?

Output: 4–8 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much QD does Candesartan have?. ### Response: 4–8 mg.


Instruction: Where is Losartan available?

Output: 25–50 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Losartan available?. ### Response: 25–50 mg.


Instruction: What is the target dose of Sacubitril/valsartan?

Output: 24/26 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target dose of Sacubitril/valsartan?. ### Response: 24/26 mg.


Instruction: How many mg BID can therapy be initiated at?

Output: 24/26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg BID can therapy be initiated at?. ### Response: 24/26.


Instruction: What is the target dose of sacubitril/valsartan?

Output: 24/26 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target dose of sacubitril/valsartan?. ### Response: 24/26 mg.


Instruction: How many mg QD are there?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg QD are there?. ### Response: 25.


Instruction: What is another name for Aldosterone antagonists Spironolactone?

Output: BID 26 mg QD 142 Eplerenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Aldosterone antagonists Spironolactone?. ### Response: BID 26 mg QD 142 Eplerenone.


Instruction: What is Spironolactone?

Output: Aldosterone antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Spironolactone?. ### Response: Aldosterone antagonists.


Instruction: What is Eplerenone?

Output: 25 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Eplerenone?. ### Response: 25 mg.


Instruction: How much is Bisoprolol worth?

Output: 1.25 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much is Bisoprolol worth?. ### Response: 1.25 mg.


Instruction: What is Carvedilol CR 10 mg?

Output: QD 80 mg QD N/A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Carvedilol CR 10 mg?. ### Response: QD 80 mg QD N/A.


Instruction: What is Metoprolol succinate extended release?

Output: metoprolol CR/XL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Metoprolol succinate extended release?. ### Response: metoprolol CR/XL.


Instruction: Isosorbide dinitrate and what else?

Output: hydralazine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Isosorbide dinitrate and what else?. ### Response: hydralazine.


Instruction: What is the name of the book that treats heart failure?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that treats heart failure?. ### Response: Chronic Heart Failure.


Instruction: Who is the author of Chronic Heart Failure Treating Heart Failure?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Chronic Heart Failure Treating Heart Failure?. ### Response: NICE 2018.


Instruction: What should you do before and after each dose increment of an MRA?

Output: Measure blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should you do before and after each dose increment of an MRA?. ### Response: Measure blood pressure.


Instruction: What is the NICE guideline on hypertension in adults?

Output: measuring blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NICE guideline on hypertension in adults?. ### Response: measuring blood pressure.


Instruction: How should you measure blood pressure in people with symptoms of postural hypotension?

Output: before and after each dose increment of an MRA. Follow the recommendations on measuring blood pressure, including measurement in people with symptoms of postural hypotension, in the NICE guideline on hypertension in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should you measure blood pressure in people with symptoms of postural hypotension?. ### Response: before and after each dose increment of an MRA. Follow the recommendations on measuring blood pressure, including measurement in people with symptoms of postural hypotension, in the NICE guideline on hypertension in adults.


Instruction: Dosage of an MRA is reached, monitor t reatment monthly for 3 months and then at least every 6 months?

Output: Once the target

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dosage of an MRA is reached, monitor t reatment monthly for 3 months and then at least every 6 months?. ### Response: Once the target.


Instruction: At any time the person becomes acutely unwell, what are the relative values of different outcomes considered?

Output: low to very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At any time the person becomes acutely unwell, what are the relative values of different outcomes considered?. ### Response: low to very low quality.


Instruction: What were considered to be critical for this review?

Output: Relative values of different outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were considered to be critical for this review?. ### Response: Relative values of different outcomes.


Instruction: What were preferred to data limited to heart failure related mortality and hospitalisations?

Output: Data on all -cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were preferred to data limited to heart failure related mortality and hospitalisations?. ### Response: Data on all -cause mortality.


Instruction: What are some of the unintended consequences of interventions?

Output: an increase in mortality or hospitalisations due to adverse events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the unintended consequences of interventions?. ### Response: an increase in mortality or hospitalisations due to adverse events.


Instruction: What were also considered to be important for the improvement of NYHA class?

Output: adverse events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were also considered to be important for the improvement of NYHA class?. ### Response: adverse events.


Instruction: Hypotension, and gynaecomastia were considered to be important for what?

Output: decision -making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypotension, and gynaecomastia were considered to be important for what?. ### Response: decision -making.


Instruction: Evidence was identified for all outcomes except for what outcome?

Output: quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence was identified for all outcomes except for what outcome?. ### Response: quality of life.


Instruction: The evidence for eplerenone and spironolactone was analysed toget her for what outcomes?

Output: all outcomes except for gynaecomastia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The evidence for eplerenone and spironolactone was analysed toget her for what outcomes?. ### Response: all outcomes except for gynaecomastia.


Instruction: Why were the 2 interventions analysed separately?

Output: gynaecomastia being a common adverse effect of spironolactone but an uncommon  effect of  eplerenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were the 2 interventions analysed separately?. ### Response: gynaecomastia being a common adverse effect of spironolactone but an uncommon  effect of  eplerenone.


Instruction: What is gynaecomastia a common adverse effect of?

Output: spironolactone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is gynaecomastia a common adverse effect of?. ### Response: spironolactone.


Instruction: What is an uncommon effect of eplerenone?

Output: gynaecomastia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an uncommon effect of eplerenone?. ### Response: gynaecomastia.


Instruction: What was graded low to very low quality due to indirectness?

Output: mortality , all-cause hospitalisation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was graded low to very low quality due to indirectness?. ### Response: mortality , all-cause hospitalisation.


Instruction: What was based on the confidence intervals around the relative effect?

Output: impre cision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was based on the confidence intervals around the relative effect?. ### Response: impre cision.


Instruction: What is cision based on?

Output: confidence intervals around the relative effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cision based on?. ### Response: confidence intervals around the relative effect.


Instruction: What is inconsistency due to in a study with a small sample size?

Output: heterogeneity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is inconsistency due to in a study with a small sample size?. ### Response: heterogeneity.


Instruction: The committee noted that the confidence intervals around the relative effect were what?

Output: impre cision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee noted that the confidence intervals around the relative effect were what?. ### Response: impre cision.


Instruction: What were the confidence intervals around the absolute effect?

Output: reasonably narrow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the confidence intervals around the absolute effect?. ### Response: reasonably narrow.


Instruction: What was the quality of the evidence for the important outcomes?

Output: low to very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence for the important outcomes?. ### Response: low to very low quality.


Instruction: The committee was confident that in each case that there was a clinically important effect.

Output: all-cause mortality and all-cause hospitalisation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee was confident that in each case that there was a clinically important effect.. ### Response: all-cause mortality and all-cause hospitalisation.


Instruction: What was the quality of the evidence for the adverse event of hyperkalaemia?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence for the adverse event of hyperkalaemia?. ### Response: low.


Instruction: What was likely underestimated?

Output: the incidence of hyperka laemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was likely underestimated?. ### Response: the incidence of hyperka laemia.


Instruction: How much was the incidence of hyperka laemia far exceeded by the evidence?

Output: 17%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the incidence of hyperka laemia far exceeded by the evidence?. ### Response: 17%)..


Instruction: What was the incidence of hyperkalaemia?

Output: 7 %

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the incidence of hyperkalaemia?. ### Response: 7 %.


Instruction: What was far exceeded by the rate of drug discontinuation?

Output: incidence of hyperkalaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was far exceeded by the rate of drug discontinuation?. ### Response: incidence of hyperkalaemia.


Instruction: The quality of the evidence varied for what?

Output: deterioration in renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The quality of the evidence varied for what?. ### Response: deterioration in renal function.


Instruction: How many meta-analyses did Blood have in 2002?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many meta-analyses did Blood have in 2002?. ### Response: 2.


Instruction: What is the name of the family history of patients with primary or secondary antiphos-pholipid syndrome?

Output: Weber M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the family history of patients with primary or secondary antiphos-pholipid syndrome?. ### Response: Weber M.


Instruction: How many patients had APS in 2000?

Output: 258–263

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had APS in 2000?. ### Response: 258–263.


Instruction: What is the name of the family study of anti-cardiolipin antibodies and associated clinical conditions?

Output: Goldberg SN, Conti-Kelly AM, Greco TP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the family study of anti-cardiolipin antibodies and associated clinical conditions?. ### Response: Goldberg SN, Conti-Kelly AM, Greco TP.


Instruction: What is a rare bleeding disorder in children: identification and pri-mary care management?

Output: Acharya SS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a rare bleeding disorder in children: identification and pri-mary care management?. ### Response: Acharya SS.


Instruction: What is the name of the disease that affects Caucasians?

Output: Familial moyamoya

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects Caucasians?. ### Response: Familial moyamoya.


Instruction: What are the names of the patients with moyamoya disease?

Output: Shetty-Alva N, Alva S. Familial moyamoya disease in Caucasians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the patients with moyamoya disease?. ### Response: Shetty-Alva N, Alva S. Familial moyamoya disease in Caucasians.


Instruction: When did Grantham publish his work?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Grantham publish his work?. ### Response: April 28, 2023.


Instruction: Where does this guideline place CG68?

Output: QS2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does this guideline place CG68?. ### Response: QS2.


Instruction: What is t he basis of QS2?

Output: CG68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he basis of QS2?. ### Response: CG68.


Instruction: This guideline co vers int erventions in what stage?

Output: t he acut e stage of a str oke or transient ischaemic attack

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: This guideline co vers int erventions in what stage?. ### Response: t he acut e stage of a str oke or transient ischaemic attack.


Instruction: In what year did we review the evidence on stroke and TIA?

Output: 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did we review the evidence on stroke and TIA?. ### Response: 2022.


Instruction: What did we make in April 2022?

Output: new r ecommendations on blood pressur e contr ol for people wit h acut e intracer ebral haemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we make in April 2022?. ### Response: new r ecommendations on blood pressur e contr ol for people wit h acut e intracer ebral haemorrhage.


Instruction: What are r ecommendations on blood pressur e contr ol for people wit h acut e intracer ebral haemorrhage?

Output: Commissioners and pr oviders of ser vices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are r ecommendations on blood pressur e contr ol for people wit h acut e intracer ebral haemorrhage?. ### Response: Commissioners and pr oviders of ser vices.


Instruction: Who are i t for?

Output: Healt hcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who are i t for?. ### Response: Healt hcare professionals.


Instruction: Commissioners and pr oviders of ser vices?

Output: People aged o ver 16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Commissioners and pr oviders of ser vices?. ### Response: People aged o ver 16.


Instruction: How old are people who have had a str oke or TIA, heir families and carers?

Output: 16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are people who have had a str oke or TIA, heir families and carers?. ### Response: 16.


Instruction: What is the name of the book that describes the diagnosis and initial management of Stroke and transient ischaemic attack in o ver 16s?

Output: NG128

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes the diagnosis and initial management of Stroke and transient ischaemic attack in o ver 16s?. ### Response: NG128.


Instruction: What year did NICE 2023 take place?

Output: 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did NICE 2023 take place?. ### Response: 2022.


Instruction: What is the last date of updat?

Output: 13 April 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last date of updat?. ### Response: 13 April 2022.


Instruction: What is enoxaparin vs unfrac-tionated heparin used for in high-risk patients with non-ST-segment elevationacute coronary syndromes managed with an intended early invasivestrategy?

Output: elective percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin vs unfrac-tionated heparin used for in high-risk patients with non-ST-segment elevationacute coronary syndromes managed with an intended early invasivestrategy?. ### Response: elective percutaneous coronary intervention.


Instruction: What was the primary outcome of the SYNERGY randomized trial?

Output: Enoxaparin vs unfrac-tionated heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome of the SYNERGY randomized trial?. ### Response: Enoxaparin vs unfrac-tionated heparin.


Instruction: When was the JAMA published?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 2004.


Instruction: How long did the STEEPLE trial last?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the STEEPLE trial last?. ### Response: 1-year.


Instruction: What is enoxaparin versus unfractionated heparin?

Output: Enoxaparin versus unfrac-tionated heparin in elective percutaneous coronary intervention 1-yearresults from the STEEPLE (SafeTy and efficacy of enoxaparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin versus unfractionated heparin?. ### Response: Enoxaparin versus unfrac-tionated heparin in elective percutaneous coronary intervention 1-yearresults from the STEEPLE (SafeTy and efficacy of enoxaparin.


Instruction: What is the efficacy of enoxaparin in per-cutaneous coronary intervention patients, an international randomizedevaluation) trial?

Output: STEEPLE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the efficacy of enoxaparin in per-cutaneous coronary intervention patients, an international randomizedevaluation) trial?. ### Response: STEEPLE.


Instruction: What is the name of the SUPPLEMENT e43Sratio in patients transitioning from argatroban to warfarin?

Output: Pharmacotherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the SUPPLEMENT e43Sratio in patients transitioning from argatroban to warfarin?. ### Response: Pharmacotherapy.


Instruction: What does Bartholomew J do in patients with heparin-induced thrombocytopenia?

Output: Transition to an oral anticoagulant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Bartholomew J do in patients with heparin-induced thrombocytopenia?. ### Response: Transition to an oral anticoagulant.


Instruction: What is the name of the study that focuses on the transition to an oral anticoagulant?

Output: Clin Appl Thromb Hemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that focuses on the transition to an oral anticoagulant?. ### Response: Clin Appl Thromb Hemost.


Instruction: What is the difference between argatroban and warfarin in hepa-rin-induced thrombocytopenia?

Output: Transitioning from argatroban to warfarin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between argatroban and warfarin in hepa-rin-induced thrombocytopenia?. ### Response: Transitioning from argatroban to warfarin therapy.


Instruction: When did Clin Appl Thromb Hemost publish a report on transitioning from argatroben to warfarine therapy?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Clin Appl Thromb Hemost publish a report on transitioning from argatroben to warfarine therapy?. ### Response: 2005.


Instruction: What is a direct thrombin inhibitor studied by?

Output: dynamic whole blood clot formation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a direct thrombin inhibitor studied by?. ### Response: dynamic whole blood clot formation.


Instruction: What is the haemostatic response?

Output: ex-vivo addition of recombinant factor VIIa or activated prothrombin complex concentrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the haemostatic response?. ### Response: ex-vivo addition of recombinant factor VIIa or activated prothrombin complex concentrate.


Instruction: What is an inhibitor studied by?

Output: dynamic whole blood clot formation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an inhibitor studied by?. ### Response: dynamic whole blood clot formation.


Instruction: What is a haemostatic response to ex-vivo addition of recombinant factor VIIa or activated prothrombin complex concentrate?

Output: Thromb Haemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a haemostatic response to ex-vivo addition of recombinant factor VIIa or activated prothrombin complex concentrate?. ### Response: Thromb Haemost.


Instruction: Novastan is a direct thrombin inhibitor of what drug?

Output: argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Novastan is a direct thrombin inhibitor of what drug?. ### Response: argatroban.


Instruction: What drug is Novastan a brand of?

Output: argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is Novastan a brand of?. ### Response: argatroban.


Instruction: Novastan is a small-molecule, direct thrombin inhibitor, what is it called?

Output: argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Novastan is a small-molecule, direct thrombin inhibitor, what is it called?. ### Response: argatroban.


Instruction: What is Novastan's name?

Output: argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Novastan's name?. ### Response: argatroban.


Instruction: What are the effects of age, gender, and hepatic or renal dysfunction on argatroban?

Output: The pharmacokinetics and phar-macodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects of age, gender, and hepatic or renal dysfunction on argatroban?. ### Response: The pharmacokinetics and phar-macodynamics.


Instruction: What is the pharmacokinetics and phar-macodynamics?

Output: effects of age, gender, and hepatic or renal dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pharmacokinetics and phar-macodynamics?. ### Response: effects of age, gender, and hepatic or renal dysfunction.


Instruction: How many ( 3 ): 318 - 329?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 3 ): 318 - 329?. ### Response: 20.


Instruction: What are the differences in the clinically?

Output: effec-tive molar concentrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences in the clinically?. ### Response: effec-tive molar concentrations.


Instruction: What is the name of the person who was a part of the study?

Output: Kimberly Henricks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who was a part of the study?. ### Response: Kimberly Henricks.


Instruction: Who is the author of the paper?

Output: Kimberly Henricks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the paper?. ### Response: Kimberly Henricks.


Instruction: How many direct thrombin inhibitors are there?

Output: four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many direct thrombin inhibitors are there?. ### Response: four.


Instruction: How many molar concentrations were there in 2005?

Output: 958 - 964

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many molar concentrations were there in 2005?. ### Response: 958 - 964.


Instruction: What assay was used to predict the international normalized  2012 American College of Chest Physicians by Arpino PA, Demirjian Z, Van Cott EM?

Output: chromo-genic factor X

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What assay was used to predict the international normalized  2012 American College of Chest Physicians by Arpino PA, Demirjian Z, Van Cott EM?. ### Response: chromo-genic factor X.


Instruction: What year was the American College of Chest Physicians normalized?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the American College of Chest Physicians normalized?. ### Response: 2012.


Instruction: What year did Kimberly Henricks normalize?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Kimberly Henricks normalize?. ### Response: 2012.


Instruction: Where was the chestjournal.chestpubs.org downloaded from?

Output: American College of Chest Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the chestjournal.chestpubs.org downloaded from?. ### Response: American College of Chest Physicians.


Instruction: What are wearable hemodynamic sensors used for?

Output: AccuracynFalse alertnCost-effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are wearable hemodynamic sensors used for?. ### Response: AccuracynFalse alertnCost-effectiveness.


Instruction: What are some of the things that need to be done to prevent arrhythmias?

Output: medication and lifestyle adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the things that need to be done to prevent arrhythmias?. ### Response: medication and lifestyle adherence.


Instruction: What are some of the reasons for nonadherence?

Output: Patient nPerceived lack of effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the reasons for nonadherence?. ### Response: Patient nPerceived lack of effect.


Instruction: What is a common cause of nonadherence in the HF team?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of nonadherence in the HF team?. ### Response: heart failure.


Instruction: What are mental health conditions?

Output: depression, anxiety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are mental health conditions?. ### Response: depression, anxiety.


Instruction: What is cognitive impairment?

Output: dementia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cognitive impairment?. ### Response: dementia.


Instruction: What is the effect of comorbidities?

Output: depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of comorbidities?. ### Response: depression.


Instruction: What is the problem with navigating patient assistance programsHF14heart failure?

Output: No automatic re ﬁllsnDifﬁculty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the problem with navigating patient assistance programsHF14heart failure?. ### Response: No automatic re ﬁllsnDifﬁculty.


Instruction: What was the date of the update to 2017 ECDP?

Output: FEBRUARY

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the date of the update to 2017 ECDP?. ### Response: FEBRUARY.


Instruction: What are GDMT beta blockers for?

Output: SIHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are GDMT beta blockers for?. ### Response: SIHD.


Instruction: What is not as effective as other antihy-pertensive drugs in the treatment of hypertension?

Output: Atenolol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not as effective as other antihy-pertensive drugs in the treatment of hypertension?. ### Response: Atenolol.


Instruction: What are effective antianginal drugs that can lower BP and relieve angina pectoris when added to beta blockers in patients with hypertension?

Output: Dihydropyridine CCBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are effective antianginal drugs that can lower BP and relieve angina pectoris when added to beta blockers in patients with hypertension?. ### Response: Dihydropyridine CCBs.


Instruction: What type of drugs are effective in low-ering BP?

Output: GDMT beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of drugs are effective in low-ering BP?. ### Response: GDMT beta blockers.


Instruction: How much did beta blockers reduce all-cause mortality in long-term trials?

Output: 23%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did beta blockers reduce all-cause mortality in long-term trials?. ### Response: 23%..


Instruction: What is the efficacy of beta blocks for treating hy-pertension and SIHD?

Output: their use for treatment continuing beyond 3 years after MI is reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the efficacy of beta blocks for treating hy-pertension and SIHD?. ### Response: their use for treatment continuing beyond 3 years after MI is reasonable.


Instruction: What are effective antihypertensive and antianginal agents?

Output: GDMT beta blockers and CCBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are effective antihypertensive and antianginal agents?. ### Response: GDMT beta blockers and CCBs.


Instruction: What are GDMT beta blockers and CCBs?

Output: effective antihyper -tensive and antianginal agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are GDMT beta blockers and CCBs?. ### Response: effective antihyper -tensive and antianginal agents.


Instruction: What is the class of recommendation in Table 1?

Output: GDMT beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of recommendation in Table 1?. ### Response: GDMT beta blockers.


Instruction: What are GDMT beta blockers used for?

Output: BP control or relief of angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are GDMT beta blockers used for?. ### Response: BP control or relief of angina.


Instruction: What is the beta blocker atenolol less effective than?

Output: placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the beta blocker atenolol less effective than?. ### Response: placebo.


Instruction: What does ACE stand for?

Output: angiotensin-converting enzyme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACE stand for?. ### Response: angiotensin-converting enzyme.


Instruction: ARB stands for what?

Output: angiotensin receptor blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ARB stands for what?. ### Response: angiotensin receptor blocker.


Instruction: BP stands for blood pressure, what does CCB mean?

Output: calcium channel blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BP stands for blood pressure, what does CCB mean?. ### Response: calcium channel blocker.


Instruction: What is GDMT?

Output: guideline-directed management and therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GDMT?. ### Response: guideline-directed management and therapy.


Instruction: What is SIHD?

Output: stable ischemic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SIHD?. ### Response: stable ischemic heart disease.


Instruction: When was this article downloaded?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: May 3, 2023.


Instruction: How much did influenza vaccination reduce the risk of mortality during the winter period?

Output: 37%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did influenza vaccination reduce the risk of mortality during the winter period?. ### Response: 37%.


Instruction: What did the influenza vaccine not reduce during the summer?

Output: risk of mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the influenza vaccine not reduce during the summer?. ### Response: risk of mortality.


Instruction: How many years of age did the Acohort study show in patients with heart failure or IHD?

Output: 806,807

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of age did the Acohort study show in patients with heart failure or IHD?. ### Response: 806,807.


Instruction: How many vaccinations were needed to prevent 1 death during 1 influenza period?

Output: 122

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many vaccinations were needed to prevent 1 death during 1 influenza period?. ### Response: 122.


Instruction: What was another mechanistic and confir-e406 Circulation December 18/25, 2012 arrest with perindopril compared with placebo?

Output: 808

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was another mechanistic and confir-e406 Circulation December 18/25, 2012 arrest with perindopril compared with placebo?. ### Response: 808.


Instruction: How many Stroke deaths were there in December 2014?

Output: 3832

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Stroke deaths were there in December 2014?. ### Response: 3832.


Instruction: What is the Cochrane Database Syst Rev. 2007:CD000409?

Output: Educational outreach visits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Cochrane Database Syst Rev. 2007:CD000409?. ### Response: Educational outreach visits.


Instruction: Cohen SJ, Halvorson HW, Gosselink CA. What does changing physician behavior do?

Output: improve disease prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cohen SJ, Halvorson HW, Gosselink CA. What does changing physician behavior do?. ### Response: improve disease prevention.


Instruction: How did Backer EL, Geske JA, McIlvain HE, Dodendorf DM, Minier WC improve female preventive health care delivery through prac-tice change?

Output: Every Woman Matters study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Backer EL, Geske JA, McIlvain HE, Dodendorf DM, Minier WC improve female preventive health care delivery through prac-tice change?. ### Response: Every Woman Matters study.


Instruction: What is an Every Woman Matters study?

Output: Improving female preventive health care delivery through prac-tice change

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an Every Woman Matters study?. ### Response: Improving female preventive health care delivery through prac-tice change.


Instruction: How did Fine LJ, Cutler JA understand and reduce therapeutic inertia?

Output: Hypertension and the treating physician

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Fine LJ, Cutler JA understand and reduce therapeutic inertia?. ### Response: Hypertension and the treating physician.


Instruction: What does the treating physician understand and reduce?

Output: therapeutic inertia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the treating physician understand and reduce?. ### Response: therapeutic inertia.


Instruction: Hypertension. 2006;47:319–320. 936.

Output: Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertension. 2006;47:319–320. 936.. ### Response: Hypertension.


Instruction: What is the cluster-randomised evaluation of?

Output: clinical and cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cluster-randomised evaluation of?. ### Response: clinical and cost effectiveness.


Instruction: What is a cluster-randomised evaluation of clinical and cost effectiveness called?

Output: Multifaceted implementation of stroke prevention guidelines in primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cluster-randomised evaluation of clinical and cost effectiveness called?. ### Response: Multifaceted implementation of stroke prevention guidelines in primary care.


Instruction: What is the name of the study that evaluated the effectiveness of community stroke risk screening?

Output: a ran-domized controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the effectiveness of community stroke risk screening?. ### Response: a ran-domized controlled trial.


Instruction: When was the run-domized controlled trial?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the run-domized controlled trial?. ### Response: 2011.


Instruction: What does CART stand for?

Output: Comprehensive Annotated Reminder Tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CART stand for?. ### Response: Comprehensive Annotated Reminder Tool.


Instruction: What is the name of the tool used to improve the delivery of preventive health care?

Output: Comprehensive Annotated Reminder Tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the tool used to improve the delivery of preventive health care?. ### Response: Comprehensive Annotated Reminder Tool.


Instruction: What do quality improvement initiatives improve among veterans?

Output: hypertension care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do quality improvement initiatives improve among veterans?. ### Response: hypertension care.


Instruction: How many randomized controlled trials did the meta-analysis of 16 randomised controlled trials evaluate?

Output: computer-based clinical reminder sys-tems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized controlled trials did the meta-analysis of 16 randomised controlled trials evaluate?. ### Response: computer-based clinical reminder sys-tems.


Instruction: In what setting is care in the ambulatory setting?

Output: preventive care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what setting is care in the ambulatory setting?. ### Response: preventive care.


Instruction: In what year did the J Am Med Inform Assoc. 1996:3:399–409 occur?

Output: 2001;50:W242–W249. 942. Frijling B, Hulscher ME, van Leest LA, Braspenning JC, van den Hoogen H, Drenthen AJ, Grol RP. Multifaceted support to improve preventive cardiovascular care: a nationwide, controlled trial in general practice. Br J Gen Pract. 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the J Am Med Inform Assoc. 1996:3:399–409 occur?. ### Response: 2001;50:W242–W249. 942. Frijling B, Hulscher ME, van Leest LA, Braspenning JC, van den Hoogen H, Drenthen AJ, Grol RP. Multifaceted support to improve preventive cardiovascular care: a nationwide, controlled trial in general practice. Br J Gen Pract. 2003.


Instruction: What is the process evaluation of a tailored multifaceted approach to changing family physician practice patterns?

Output: improving preventive care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the process evaluation of a tailored multifaceted approach to changing family physician practice patterns?. ### Response: improving preventive care.


Instruction: What is a nationwide, controlled trial in general practice?

Output: Multifaceted support to improve preventive cardiovascular care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a nationwide, controlled trial in general practice?. ### Response: Multifaceted support to improve preventive cardiovascular care.


Instruction: What does multifaceted support to improve preventive cardiovascular care?

Output: a nationwide, controlled trial in general practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does multifaceted support to improve preventive cardiovascular care?. ### Response: a nationwide, controlled trial in general practice.


Instruction: What did Hulscher ME, Maglione MA, Roth EA, Grimshaw JM, Mittman BS, Rubenstein LZ, Shekelle PG, and Mojica W do?

Output: Interventions that increase use of adult immunization and cancer screening services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Hulscher ME, Maglione MA, Roth EA, Grimshaw JM, Mittman BS, Rubenstein LZ, Shekelle PG, and Mojica W do?. ### Response: Interventions that increase use of adult immunization and cancer screening services.


Instruction: What did the meta-analysis show about interventions that increase use of immunization and cancer screening services?

Output: 641–651

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the meta-analysis show about interventions that increase use of immunization and cancer screening services?. ### Response: 641–651.


Instruction: What is the impact of health information technol-ogy on quality, efficiency, and costs of medical care?

Output: Systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of health information technol-ogy on quality, efficiency, and costs of medical care?. ### Response: Systematic review.


Instruction: What is a systematic review of?

Output: impact of health information technol-ogy on quality, efficiency, and costs of medical care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of?. ### Response: impact of health information technol-ogy on quality, efficiency, and costs of medical care.


Instruction: How is quality of stroke prevention in general evaluated?

Output: relationship with practice organization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is quality of stroke prevention in general evaluated?. ### Response: relationship with practice organization.


Instruction: What is the relationship between practice organization and quality of stroke prevention?

Output: Quality of stroke prevention in general practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between practice organization and quality of stroke prevention?. ### Response: Quality of stroke prevention in general practice.


Instruction: Int J Qual Health Care. 2005;17:59-65.

Output: Quality of stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Qual Health Care. 2005;17:59-65.. ### Response: Quality of stroke prevention.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett et al.


Instruction: What is the DOI for the Clinical Statements and Guidlines regarding glycaemic control?

Output: 10.1161/CIR.0000000000000678 e626

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI for the Clinical Statements and Guidlines regarding glycaemic control?. ### Response: 10.1161/CIR.0000000000000678 e626.


Instruction: What is the name of the study that evaluated the effectiveness and safety of patient activation interventions for adults with type 2 diabetes?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the effectiveness and safety of patient activation interventions for adults with type 2 diabetes?. ### Response: Arnett et al.


Instruction: What are the implications for research and practice for psychosocial fac-tors in medication adherence and diabetes self-management?

Output: Implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the implications for research and practice for psychosocial fac-tors in medication adherence and diabetes self-management?. ### Response: Implications.


Instruction: What are the implications for research and practice in diabetes self-management?

Output: Psychosocial fac-tors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the implications for research and practice in diabetes self-management?. ### Response: Psychosocial fac-tors.


Instruction: What is the name of the multi-ethnic study of atherosclerosis?

Output: Social engage-ment and chronic disease risk behaviors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-ethnic study of atherosclerosis?. ### Response: Social engage-ment and chronic disease risk behaviors.


Instruction: What is the Multi-Ethnic Study of Atherosclerosis?

Output: Social engage-ment and chronic disease risk behaviors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Multi-Ethnic Study of Atherosclerosis?. ### Response: Social engage-ment and chronic disease risk behaviors.


Instruction: What are the National guidelines for smoking cessation in primary care?

Output: a literature review and evidence analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the National guidelines for smoking cessation in primary care?. ### Response: a literature review and evidence analysis.


Instruction: What is the name of the 2013 ACC/AHA guideline on the assessment of cardiovascular risk?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2013 ACC/AHA guideline on the assessment of cardiovascular risk?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What was the title of the 2014 Circulation.129:S49-73?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the 2014 Circulation.129:S49-73?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What is the acronym for ASCVD Risk Estimator?

Output: American College of Cardiology, American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for ASCVD Risk Estimator?. ### Response: American College of Cardiology, American Heart Association.


Instruction: Where can you find this information?

Output: https://tools.acc.org/ldl/ascvd_risk_estimator/index.html#!/calulate/estimator. Accessed September 21, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find this information?. ### Response: https://tools.acc.org/ldl/ascvd_risk_estimator/index.html#!/calulate/estimator. Accessed September 21, 2018.


Instruction: When was this information available?

Output: September 21, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this information available?. ### Response: September 21, 2018.


Instruction: What is this information used for?

Output: American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is this information used for?. ### Response: American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Instruction: What is the name of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol?

Output: Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol?. ### Response: Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.