Instruction: How does the risk of bleeding vary from person to person?

Output: pre-existing comorbidities, currentantithrombotic regimen and adherence, concomitantmedication, and lifestyle choices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the risk of bleeding vary from person to person?. ### Response: pre-existing comorbidities, currentantithrombotic regimen and adherence, concomitantmedication, and lifestyle choices.


Instruction: What are some of the factors that cannot be altered but are modi fiable?

Output: lifestyle choices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the factors that cannot be altered but are modi fiable?. ### Response: lifestyle choices.


Instruction: What is one way to reduce antithrombotic regimen?

Output: time in therapeutic range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one way to reduce antithrombotic regimen?. ### Response: time in therapeutic range.


Instruction: What was the focus of the 2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction?

Output: Author Relationships With Industry and Other Entities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the 2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction?. ### Response: Author Relationships With Industry and Other Entities.


Instruction: When was the ST-elevation MMI Writing Committee created?

Output: February 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ST-elevation MMI Writing Committee created?. ### Response: February 2014.


Instruction: Who is the Chair of Harvard Medical School?

Output: Patrick T. O’Gara

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of Harvard Medical School?. ### Response: Patrick T. O’Gara.


Instruction: Who is the Vice Chair of Tulane University School ofMedicine?

Output: Frederick G. Kushner

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Chair of Tulane University School ofMedicine?. ### Response: Frederick G. Kushner.


Instruction: What is the name of the medical director of Heart Clinic ofLouisiana?

Output: Frederick G. Kushner

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the medical director of Heart Clinic ofLouisiana?. ### Response: Frederick G. Kushner.


Instruction: Who is an Associate Professor of Medicine at Mount Sinai?

Output: Deborah D. Ascheim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is an Associate Professor of Medicine at Mount Sinai?. ### Response: Deborah D. Ascheim.


Instruction: Who is the founder of the Cleveland ClinicFoundation?

Output: Mina K. Chung

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the founder of the Cleveland ClinicFoundation?. ### Response: Mina K. Chung.


Instruction: What is the name of the professor of medicine at UCSF Philip R. Lee Institute for Health PolicyStudies?

Output: Ralph G. Brindis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at UCSF Philip R. Lee Institute for Health PolicyStudies?. ### Response: Ralph G. Brindis.


Instruction: Who is a Professor ofMedicine at UT Southwestern MedicalCenter?

Output: James A. de Lemos

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Professor ofMedicine at UT Southwestern MedicalCenter?. ### Response: James A. de Lemos.


Instruction: What is the Department of Emergency Medicine's Professor and ChairNone?

Output: Distinguished Chair inClinical Care andResearch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Department of Emergency Medicine's Professor and ChairNone?. ### Response: Distinguished Chair inClinical Care andResearch.


Instruction: Who is the Chair inclinical care and research?

Output: Deborah B. Diercks UT Southwestern MedicalCenter—Audre andBernard Rapoport

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair inclinical care and research?. ### Response: Deborah B. Diercks UT Southwestern MedicalCenter—Audre andBernard Rapoport.


Instruction: What is the Department of Emergency Medicine called?

Output: —Professor and Chair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Department of Emergency Medicine called?. ### Response: —Professor and Chair.


Instruction: Who published this article on behalf of the Society for CardiovascularAngiography and Interventions?

Output: Levine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published this article on behalf of the Society for CardiovascularAngiography and Interventions?. ### Response: Levine.


Instruction: When was this article published?

Output: 1522726x

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: 1522726x.


Instruction: On what date was Wiley Online Library launched?

Output: 03/05/2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was Wiley Online Library launched?. ### Response: 03/05/2023.


Instruction: What is the name of the document that governs the use of OA articles?

Output: Creative Commons License

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that governs the use of OA articles?. ### Response: Creative Commons License.


Instruction: How is OA governed by the Creative Commons License?

Output: Terms and Conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is OA governed by the Creative Commons License?. ### Response: Terms and Conditions.


Instruction: What is the name of the guideline for chronic heart failure?

Output: Chronic Heart Failure  Guideline summary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for chronic heart failure?. ### Response: Chronic Heart Failure  Guideline summary.


Instruction: What is an assessment of renal function?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an assessment of renal function?. ### Response: Chronic Heart Failure.


Instruction: What should be needed if a person has significant comorbidity or if their condition has deteriorated since the previous review?

Output: More detailed monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be needed if a person has significant comorbidity or if their condition has deteriorated since the previous review?. ### Response: More detailed monitoring.


Instruction: The freq uency of monitoring should depend on what?

Output: clinical status and stability of the person

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The freq uency of monitoring should depend on what?. ### Response: clinical status and stability of the person.


Instruction: What should the monitoring interval be short (days to 2 weeks)?

Output: if the clinical condition or medication has changed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the monitoring interval be short (days to 2 weeks)?. ### Response: if the clinical condition or medication has changed.


Instruction: What should be short (days to 2 weeks) if the clinical condition or medication has changed?

Output: The monitoring interval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be short (days to 2 weeks) if the clinical condition or medication has changed?. ### Response: The monitoring interval.


Instruction: How often should be needed for stable people with proven heart failure?

Output: at least 6 -monthly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often should be needed for stable people with proven heart failure?. ### Response: at least 6 -monthly.


Instruction: What should people with heart failure who wish to be involved in monitoring their condition be provided?

Output: sufficient education and support from their healthcare professional

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should people with heart failure who wish to be involved in monitoring their condition be provided?. ### Response: sufficient education and support from their healthcare professional.


Instruction: What is NT -proBNP?

Output: N -terminal pro -B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NT -proBNP?. ### Response: N -terminal pro -B-type natriuretic peptide.


Instruction: What is N -terminal pro -B-type natriuretic peptide?

Output: NT -proBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is N -terminal pro -B-type natriuretic peptide?. ### Response: NT -proBNP.


Instruction: When is NT -proBNP measured?

Output: in a specialist care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is NT -proBNP measured?. ### Response: in a specialist care.


Instruction: What is the eGFR above?

Output: 60  ml/min/1.73  m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the eGFR above?. ### Response: 60  ml/min/1.73  m2.


Instruction: What should the core specialist heart failure multidisciplinary team work in collaboration with?

Output: the primary care team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the core specialist heart failure multidisciplinary team work in collaboration with?. ### Response: the primary care team.


Instruction: What is the lead physician with a subspecialty interest in heart failure?

Output: consultant cardiologist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the lead physician with a subspecialty interest in heart failure?. ### Response: consultant cardiologist.


Instruction: Who is responsible for making the clinical diagnosis?

Output: a lead physician with a subspecialty interest in heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is responsible for making the clinical diagnosis?. ### Response: a lead physician with a subspecialty interest in heart failure.


Instruction: Who is a healthcare professional with expertise in specialist prescribing for heart failure?

Output: specialist heart failure nurse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a healthcare professional with expertise in specialist prescribing for heart failure?. ### Response: specialist heart failure nurse.


Instruction: What should the specialist heart failure MDT directly involve or refer people to?

Output: other services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the specialist heart failure MDT directly involve or refer people to?. ### Response: other services.


Instruction: What should the MDT directly involve, or refer people to?

Output: other services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the MDT directly involve, or refer people to?. ### Response: other services.


Instruction: What should a specialist heart failure MDT do?

Output: work in collaboration with the primary care team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a specialist heart failure MDT do?. ### Response: work in collaboration with the primary care team.


Instruction: What is the New York Heart Association's class III to IV heart failure?

Output: advanced heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the New York Heart Association's class III to IV heart failure?. ### Response: advanced heart failure.


Instruction: How do you manage newly diagnosed, recently decompensated, or advanced heart failure (NYHA)?

Output: optimise treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do you manage newly diagnosed, recently decompensated, or advanced heart failure (NYHA)?. ### Response: optimise treatment.


Instruction: What are the classes of heart failure in NYHA?

Output: class III to IV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the classes of heart failure in NYHA?. ### Response: class III to IV.


Instruction: What should the primary care team carry out for people with heart failure?

Output: the following for people with heart failure at all times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the primary care team carry out for people with heart failure?. ### Response: the following for people with heart failure at all times.


Instruction: What should be done for people who are not responding to treatment?

Output: manage heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be done for people who are not responding to treatment?. ### Response: manage heart failure.


Instruction: Who should carry out the following for people with heart failure at all times?

Output: The primary care team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should carry out the following for people with heart failure at all times?. ### Response: The primary care team.


Instruction: What should care team carry out for people who have heart failure?

Output: monitoring of their condition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should care team carry out for people who have heart failure?. ### Response: monitoring of their condition.


Instruction: What is usually necessary to fully assess the severity of each lesion and decide on appropriate intervention?

Output: invasive hemodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is usually necessary to fully assess the severity of each lesion and decide on appropriate intervention?. ### Response: invasive hemodynamics.


Instruction: Evaluation and Selection of Prosthetic Valves11.1.1. What is summarized in Online?

Output: Diagnosis and Follow-Up of Prosthetic ValvesRecommendations for Diagnosis and Follow-Up of Prosthetic ValvesReferenced studies that support the recommendations are summarized in Online Data Supplement 34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evaluation and Selection of Prosthetic Valves11.1.1. What is summarized in Online?. ### Response: Diagnosis and Follow-Up of Prosthetic ValvesRecommendations for Diagnosis and Follow-Up of Prosthetic ValvesReferenced studies that support the recommendations are summarized in Online Data Supplement 34.


Instruction: Where are studies that support the recommendations summarized?

Output: Online Data Supplement 34.COR LOE Recommendations1 B-NR1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are studies that support the recommendations summarized?. ### Response: Online Data Supplement 34.COR LOE Recommendations1 B-NR1.


Instruction: What is recommended in patients with a surgical or transcatheter prosthetic valve?

Output: repeat TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with a surgical or transcatheter prosthetic valve?. ### Response: repeat TTE.


Instruction: In patients who have had valve repair, an initial postprocedural TTE study is recommended?

Output: annually after implantation is reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients who have had valve repair, an initial postprocedural TTE study is recommended?. ### Response: annually after implantation is reasonable.


Instruction: What is recommended for evaluation of valve hemodynamics and ventricular function?

Output: an initial postprocedural TTE study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for evaluation of valve hemodynamics and ventricular function?. ### Response: an initial postprocedural TTE study.


Instruction: In patients with a prosthetic valve or prior valve repair and a change in clinical symptoms or signs suggesting valve dysfunction, repeat TTE is recommended?

Output: bioprosthetic surgical valve, TTE at 5 and 10 years and then annually after implantation is reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with a prosthetic valve or prior valve repair and a change in clinical symptoms or signs suggesting valve dysfunction, repeat TTE is recommended?. ### Response: bioprosthetic surgical valve, TTE at 5 and 10 years and then annually after implantation is reasonable.


Instruction: What is recommended in patients with a prosthetic valve replacement or prior valve repair?

Output: repeat TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with a prosthetic valve replacement or prior valve repair?. ### Response: repeat TTE.


Instruction: What is another option for imaging?

Output: TEE, gated cardiac CT, or fluoroscopy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another option for imaging?. ### Response: TEE, gated cardiac CT, or fluoroscopy.


Instruction: How long is TTE reasonable in patients with a bioprosthetic surgical valve?

Output: 5 and 10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is TTE reasonable in patients with a bioprosthetic surgical valve?. ### Response: 5 and 10 years.


Instruction: What is reasonable even in the absence of a change in clinical status?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable even in the absence of a change in clinical status?. ### Response: TTE.


Instruction: How often is TAVI, TTE reasonable?

Output: annually

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often is TAVI, TTE reasonable?. ### Response: annually.


Instruction: Table 21. AS/MR Mixed Valve DiseaseSevere AS Severe MR Surgical Risk Procedure

Output: SAVR candidate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Table 21. AS/MR Mixed Valve DiseaseSevere AS Severe MR Surgical Risk Procedure. ### Response: SAVR candidate.


Instruction: What is MR Low intermediate?

Output: SAVRSurgical mitral valve repair/mitral valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MR Low intermediate?. ### Response: SAVRSurgical mitral valve repair/mitral valve replacement.


Instruction: What is SAVRSurgical aortic valve replacement?

Output: SAVR, surgical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SAVRSurgical aortic valve replacement?. ### Response: SAVR, surgical.


Instruction: What is the acronym for transcatheter aortic valve implantation?

Output: TAVI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for transcatheter aortic valve implantation?. ### Response: TAVI.


Instruction: What is TEER?

Output: transcatheter edge-to-edge repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TEER?. ### Response: transcatheter edge-to-edge repair.


Instruction: How many patients were treated at the Mayo Clinic from 1994 to 2005?

Output: 17,901

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated at the Mayo Clinic from 1994 to 2005?. ### Response: 17,901.


Instruction: What was the incidence of major femoral bleeding complica-tions after percutaneous coronary intervention?

Output: incidence, predictors, and impact on long-term survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the incidence of major femoral bleeding complica-tions after percutaneous coronary intervention?. ### Response: incidence, predictors, and impact on long-term survival.


Instruction: What is the focus of inpatient management of patients with acute coronary syndromes?

Output: ucose-lowering targets for patients with cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of inpatient management of patients with acute coronary syndromes?. ### Response: ucose-lowering targets for patients with cardiovascular disease.


Instruction: What are Bleding avoidance strategies?

Output: consensus and controversy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Bleding avoidance strategies?. ### Response: consensus and controversy.


Instruction: What is a U-shaped relationship of blood glucose with adverse outcomes among patients with ST-segment eleva-tion myocardial infarction?

Output: Pinto

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a U-shaped relationship of blood glucose with adverse outcomes among patients with ST-segment eleva-tion myocardial infarction?. ### Response: Pinto.


Instruction: What is the name of the study that investigated the relationship between blood glucose and adverse outcomes?

Output: Pinto DS, Skolnick AH, Kirtane AJ, et al. U-shaped

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the relationship between blood glucose and adverse outcomes?. ### Response: Pinto DS, Skolnick AH, Kirtane AJ, et al. U-shaped.


Instruction: How many patients were treated with glucometrics in 2005?

Output: 17,901

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with glucometrics in 2005?. ### Response: 17,901.


Instruction: What is the optimal outcome-based measure of risk in patients with acute myocardial infarction?

Output: Glucometrics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the optimal outcome-based measure of risk in patients with acute myocardial infarction?. ### Response: Glucometrics.


Instruction: When was Circulation 117:1018–27.570?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation 117:1018–27.570?. ### Response: 2008.


Instruction: What is Intensive versus conventional glu-cose control in critically ill patients?

Output: Out-of-hospital administra-tion of intravenous glucose-insulin-potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Intensive versus conventional glu-cose control in critically ill patients?. ### Response: Out-of-hospital administra-tion of intravenous glucose-insulin-potassium.


Instruction: What is the effect of glucose-insulin-potassium in-fusion on mortality in patients with acute ST-segment elevation myocar -dial infarction?

Output: adverse outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of glucose-insulin-potassium in-fusion on mortality in patients with acute ST-segment elevation myocar -dial infarction?. ### Response: adverse outcomes.


Instruction: What was the CREATE-ECLA randomized controlled trial?

Output: elevation myocar -dial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the CREATE-ECLA randomized controlled trial?. ### Response: elevation myocar -dial infarction.


Instruction: When was the JAMA 293:437–46.572 published?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA 293:437–46.572 published?. ### Response: 2005.


Instruction: What is the name of the randomized trial of glucose-insulin-potassium infusion inpatients treated with primary angioplasty for acute myocardial infarction?

Output: IMMEDIATE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of glucose-insulin-potassium infusion inpatients treated with primary angioplasty for acute myocardial infarction?. ### Response: IMMEDIATE.


Instruction: When did the J Am Coll Cardiol. 2003 issue 42:784–91.573?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol. 2003 issue 42:784–91.573?. ### Response: 2003.


Instruction: What was the name given to the IMMEDIATE randomized controlled trial in patients with suspected acute coronary syndrome?

Output: Out-of-hospital administra-tion of intravenous glucose-insulin-potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name given to the IMMEDIATE randomized controlled trial in patients with suspected acute coronary syndrome?. ### Response: Out-of-hospital administra-tion of intravenous glucose-insulin-potassium.


Instruction: What is the name of the IMMEDIATE randomized controlled trial?

Output: Out-of-hospital administra-tion of intravenous glucose-insulin-potassium in patients with suspected acute coronary syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the IMMEDIATE randomized controlled trial?. ### Response: Out-of-hospital administra-tion of intravenous glucose-insulin-potassium in patients with suspected acute coronary syndromes.


Instruction: When was the JAMA's 307:1925–33.574 published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA's 307:1925–33.574 published?. ### Response: 2012.


Instruction: What did Newby LK, Eisenstein EL, Califf RM, et al. Cost effectiveness of early discharge after uncomplicated acute myocardial infarction?

Output: Cost effectiveness of early discharge after uncomplicated acute myocardial infarction. N Engl J Med. 2000;342:749–55.575

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Newby LK, Eisenstein EL, Califf RM, et al. Cost effectiveness of early discharge after uncomplicated acute myocardial infarction?. ### Response: Cost effectiveness of early discharge after uncomplicated acute myocardial infarction. N Engl J Med. 2000;342:749–55.575.


Instruction: What are implications for timing of discharge and applications to medical decision-making?

Output: Time-based risk assess-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implications for timing of discharge and applications to medical decision-making?. ### Response: Time-based risk assess-ment.


Instruction: What is the length of the hospital stay after myocardial infarction?

Output: 24:182–9.576. Antman EM, Kuntz KM. The length of the hospital stay after myocardial infarction. N Engl J Med. 2000;342:808–10.577

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the length of the hospital stay after myocardial infarction?. ### Response: 24:182–9.576. Antman EM, Kuntz KM. The length of the hospital stay after myocardial infarction. N Engl J Med. 2000;342:808–10.577.


Instruction: What is a prognostic value of exercise testing soon after myocardial infarction?

Output: maximal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prognostic value of exercise testing soon after myocardial infarction?. ### Response: maximal.


Instruction: What is the GISSI-2 data-base?

Output: Gruppo Italiano per lo Studio della Sopravvivenza Nell’Infarto

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the GISSI-2 data-base?. ### Response: Gruppo Italiano per lo Studio della Sopravvivenza Nell’Infarto.


Instruction: What is the name of the data-base for throm-bolytic agents?

Output: GISSI-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the data-base for throm-bolytic agents?. ### Response: GISSI-2.


Instruction: What is the general recommendation to avoid the use of aliskiren in combination with another renin-angiotensin blocking agents in patients with hypertension?

Output: for the pri-mary prevention of CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the general recommendation to avoid the use of aliskiren in combination with another renin-angiotensin blocking agents in patients with hypertension?. ### Response: for the pri-mary prevention of CVD.


Instruction: What is the overall goal of therapy?

Output: to reduce excess morbidity and unnecessary deaths

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the overall goal of therapy?. ### Response: to reduce excess morbidity and unnecessary deaths.


Instruction: What are the surrogate end points for hypertension?

Output: BP, cholesterol, and blood glucose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the surrogate end points for hypertension?. ### Response: BP, cholesterol, and blood glucose.


Instruction: What have been established as diagnostic markers?

Output: BP, cholesterol, and blood glucose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have been established as diagnostic markers?. ### Response: BP, cholesterol, and blood glucose.


Instruction: What are surrogate end points?

Output: BP, cholesterol, and blood glucose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are surrogate end points?. ### Response: BP, cholesterol, and blood glucose.


Instruction: Distinct values of these mark-ers have been set as what?

Output: therapeutic targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Distinct values of these mark-ers have been set as what?. ### Response: therapeutic targets.


Instruction: What is the goal of 130/80 mm Hg in some individuals with diabetes mellitus or CKD?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of 130/80 mm Hg in some individuals with diabetes mellitus or CKD?. ### Response: <.


Instruction: What was the first AHA scientific statement on the treat-ment of hypertension in the prevention and management of IHD?

Output: recommended a goal of <130/80 mm Hg in individ-uals with established CAD, with CAD equivalents, or with a Framingham Risk Score of ≥ 10%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the first AHA scientific statement on the treat-ment of hypertension in the prevention and management of IHD?. ### Response: recommended a goal of <130/80 mm Hg in individ-uals with established CAD, with CAD equivalents, or with a Framingham Risk Score of ≥ 10%..


Instruction: What is the Framingham Risk Score of  10%?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Framingham Risk Score of  10%?. ### Response: ≥.


Instruction: What has suggested that the lower BP target is not supported by evi-dence from high-quality, randomized, clinical trials?

Output: meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has suggested that the lower BP target is not supported by evi-dence from high-quality, randomized, clinical trials?. ### Response: meta-analyses.


Instruction: What is the subject of intense debate?

Output: Whether the lower BP goal is appropriate for the preven-tion of coronary disease and for the treatment of established coronary disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the subject of intense debate?. ### Response: Whether the lower BP goal is appropriate for the preven-tion of coronary disease and for the treatment of established coronary disease.


Instruction: There is a historical trend for lower BP goals, especially in those with what type of damage?

Output: target-organ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is a historical trend for lower BP goals, especially in those with what type of damage?. ### Response: target-organ.


Instruction: What are specific BP treatment goals for individuals with nascent or overt CAD?

Output: ≥ 10%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are specific BP treatment goals for individuals with nascent or overt CAD?. ### Response: ≥ 10%..


Instruction: What can be argued from patho-physiological principles to reduce myocardial work-load?

Output: very low SBP values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be argued from patho-physiological principles to reduce myocardial work-load?. ### Response: very low SBP values.


Instruction: There is a concern that excessive lowering of what may impair coronary perfusion?

Output: DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is a concern that excessive lowering of what may impair coronary perfusion?. ### Response: DBP.


Instruction: There is no consensus on what should be the most appropriate BP target in individuals with latent or overt CAD?

Output: there is no consensus on the question of what the most appropriate BP target(s) should be in individuals with latent or overt CAD or prominent CAD risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no consensus on what should be the most appropriate BP target in individuals with latent or overt CAD?. ### Response: there is no consensus on the question of what the most appropriate BP target(s) should be in individuals with latent or overt CAD or prominent CAD risk factors.


Instruction: What should be in individuals with latent or overt CAD or prominent CAD risk factors?

Output: BP target

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be in individuals with latent or overt CAD or prominent CAD risk factors?. ### Response: BP target.


Instruction: What can be developed from a synthesis of the results from relevant epidemiological studies?

Output: reasonable recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be developed from a synthesis of the results from relevant epidemiological studies?. ### Response: reasonable recommendations.


Instruction: What is the J curve?

Output: theoretical issue

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J curve?. ### Response: theoretical issue.


Instruction: What are the end points of the human studies?

Output: surrogate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the end points of the human studies?. ### Response: surrogate.


Instruction: How are these end points determined?

Output: diagnostic markers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are these end points determined?. ### Response: diagnostic markers.


Instruction: What does statins and nonstatins lower in chil-dren and adolescents with FH,S4.4.4.3-30 and other health conditions put them at increased risk of?

Output: CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does statins and nonstatins lower in chil-dren and adolescents with FH,S4.4.4.3-30 and other health conditions put them at increased risk of?. ### Response: CVD.


Instruction: What is increased risk of?

Output: CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is increased risk of?. ### Response: CVD.


Instruction: What is low short- and medium-term adverse event rates with statin use in children and ado-lescents with FH?

Output: abnormalities in liver func-tion test, creatine kinase [CK] levels, and reported myopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low short- and medium-term adverse event rates with statin use in children and ado-lescents with FH?. ### Response: abnormalities in liver func-tion test, creatine kinase [CK] levels, and reported myopathy.


Instruction: What is the benefit of statins to subclinical atherosclerosis in FH?

Output: ben-efit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of statins to subclinical atherosclerosis in FH?. ### Response: ben-efit.


Instruction: What is increased risk of CVD in untreated severe hypercholester -olemia?

Output: ben-efit from statins to subclinical atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is increased risk of CVD in untreated severe hypercholester -olemia?. ### Response: ben-efit from statins to subclinical atherosclerosis.


Instruction: How old are children and adolescents at ages 10 years who have FHS4.4.4.3-33?

Output: ≥10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are children and adolescents at ages 10 years who have FHS4.4.4.3-33?. ### Response: ≥10 years.


Instruction: How many months of lifestyle therapy have not responded to?

Output: 3 to 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many months of lifestyle therapy have not responded to?. ### Response: 3 to 6.


Instruction: Statins may be considered at what age in the presence of concering family history?

Output: 8 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Statins may be considered at what age in the presence of concering family history?. ### Response: 8 years.


Instruction: What should the intensity of treatment be based on?

Output: the severity of the hyper -cholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the intensity of treatment be based on?. ### Response: the severity of the hyper -cholesterolemia.


Instruction: What should include patient/family preference?

Output: The intensity of treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should include patient/family preference?. ### Response: The intensity of treatment.


Instruction: In children with severe hypercholesterolemia, what does ezeti-mibe show?

Output: reasonable LDL-C lowering with no signifi-cant adverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In children with severe hypercholesterolemia, what does ezeti-mibe show?. ### Response: reasonable LDL-C lowering with no signifi-cant adverse effects.


Instruction: Nonsystemic bile acid sequestrants can be useful for what?

Output: LDL-C lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nonsystemic bile acid sequestrants can be useful for what?. ### Response: LDL-C lowering.


Instruction: What can identify the severe hypercholesterolemia phenotype?

Output: Lipid testing during childhood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can identify the severe hypercholesterolemia phenotype?. ### Response: Lipid testing during childhood.


Instruction: What is the LDL-C level in children and adolescents?

Output: ≥190 mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LDL-C level in children and adolescents?. ### Response: ≥190 mg/dL.


Instruction: What is it called when a child has a family history of early atherosclerosis or similarly elevated cho-lesterol in 1 parent?

Output: Statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is it called when a child has a family history of early atherosclerosis or similarly elevated cho-lesterol in 1 parent?. ### Response: Statins.


Instruction: What are genetic disorders associated with accel-erated ASCVD?

Output: FH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are genetic disorders associated with accel-erated ASCVD?. ### Response: FH.


Instruction: What do subclinical ath-erosclerosis data suggest divergence between affected and unaffected children and adolescents beginning at?

Output: age 10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do subclinical ath-erosclerosis data suggest divergence between affected and unaffected children and adolescents beginning at?. ### Response: age 10 years.


Instruction: At what age is screening recommended?

Output: 2 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what age is screening recommended?. ### Response: 2 years.


Instruction: At what age should a family his-tory be suggestive of CVD or primary hypercholesterolemia?

Output: 2 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what age should a family his-tory be suggestive of CVD or primary hypercholesterolemia?. ### Response: 2 years.


Instruction: What should prompt screening of extended family members?

Output: Identification of a child with severe hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should prompt screening of extended family members?. ### Response: Identification of a child with severe hypercholesterolemia.


Instruction: What does screening for hypercholesterolemia on the basis of family history include an expanded group of?

Output: family

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does screening for hypercholesterolemia on the basis of family history include an expanded group of?. ### Response: family.


Instruction: What should the decision to perform imaging with nuclear or echocardiographic techniques along with stress ECG be based on?

Output: manyfactors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the decision to perform imaging with nuclear or echocardiographic techniques along with stress ECG be based on?. ### Response: manyfactors.


Instruction: What is the likelihood of garnering substantialcremental prognostic information that is likely to alterclinical and therapeutic management?

Output: capable patient with a normal baseline ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the likelihood of garnering substantialcremental prognostic information that is likely to alterclinical and therapeutic management?. ### Response: capable patient with a normal baseline ECG.


Instruction: Cost-Effectiveness of testing strategies insymptomatic patients have been used to inform responses to what?

Output: healthcare costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cost-Effectiveness of testing strategies insymptomatic patients have been used to inform responses to what?. ### Response: healthcare costs.


Instruction: To be of value, estimates of cost-effectiveness must use contemporary estimates of effic-tiveness that incorporate considerations of disease prevalence and what else?

Output: test accuracy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To be of value, estimates of cost-effectiveness must use contemporary estimates of effic-tiveness that incorporate considerations of disease prevalence and what else?. ### Response: test accuracy.


Instruction: Costs must reflect not only the index test but also what other factor?

Output: episode of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Costs must reflect not only the index test but also what other factor?. ### Response: episode of care.


Instruction: What must the costs reflect?

Output: estimates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must the costs reflect?. ### Response: estimates.


Instruction: Where would the data derived from be derived?

Output: RCTs orregistries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where would the data derived from be derived?. ### Response: RCTs orregistries.


Instruction: What provide general estimates of thecost-effectiveness of various forms of testing?

Output: mixed methods anddecision analytic models

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provide general estimates of thecost-effectiveness of various forms of testing?. ### Response: mixed methods anddecision analytic models.


Instruction: Mixed methods use observational evidence of what?

Output: index and downstream proce-dures, hospitalization, and drug costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Mixed methods use observational evidence of what?. ### Response: index and downstream proce-dures, hospitalization, and drug costs.


Instruction: Decision analytic models use what to estimate cumulative costs?

Output: clinical and financial data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Decision analytic models use what to estimate cumulative costs?. ### Response: clinical and financial data.


Instruction: What do decision analyticmodels simulate?

Output: clinical and financial data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do decision analyticmodels simulate?. ### Response: clinical and financial data.


Instruction: What do inherent assumptions and uncertainties with regard to the data and incomplete consideration of risks andbenefits require?

Output: such calculations be considered asestimates only

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do inherent assumptions and uncertainties with regard to the data and incomplete consideration of risks andbenefits require?. ### Response: such calculations be considered asestimates only.


Instruction: Stress imaging is estimated to provide what over most studies?

Output: abenefit over exercise ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stress imaging is estimated to provide what over most studies?. ### Response: abenefit over exercise ECG.


Instruction: What is estimated to provide abenefit over exercise ECG at a reasonable cost?

Output: stress imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is estimated to provide abenefit over exercise ECG at a reasonable cost?. ### Response: stress imaging.


Instruction: What is the threshold for economic efficiency of /H11021$50 000 per addedyear of life?

Output: commensu-rate with accepted values for cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the threshold for economic efficiency of /H11021$50 000 per addedyear of life?. ### Response: commensu-rate with accepted values for cost effectiveness.


Instruction: What type of ECG is more frequent for those with negative exercise ECG?

Output: angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of ECG is more frequent for those with negative exercise ECG?. ### Response: angiography.


Instruction: What do some people prefer to do with exercise echocardiography and others favor exercise nuclear MPI?

Output: somefavoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do some people prefer to do with exercise echocardiography and others favor exercise nuclear MPI?. ### Response: somefavoring.


Instruction: The patient’s pretest likelihood of CAD also influences what?

Output: cost-effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The patient’s pretest likelihood of CAD also influences what?. ### Response: cost-effectiveness.


Instruction: How is exercise echocardiography more cost-effective in lower-risk patients?

Output: The patient’s pretest likelihood of CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is exercise echocardiography more cost-effective in lower-risk patients?. ### Response: The patient’s pretest likelihood of CAD.


Instruction: What is less cost effective in patients with a pretest probability /H1102175%?

Output: Use of invasive coronaryangiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less cost effective in patients with a pretest probability /H1102175%?. ### Response: Use of invasive coronaryangiography.


Instruction: What is not cost-effective in patients with a pretest probability/H1102175%?

Output: Use of invasive coronaryangiography as a first test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not cost-effective in patients with a pretest probability/H1102175%?. ### Response: Use of invasive coronaryangiography as a first test.


Instruction: As the reimbursement for stress imaging decreases, what is more favorable than that of exercise ECG?

Output: cost-effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: As the reimbursement for stress imaging decreases, what is more favorable than that of exercise ECG?. ### Response: cost-effectiveness.


Instruction: What is more favorable than that of exercise ECG?

Output: stress imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more favorable than that of exercise ECG?. ### Response: stress imaging.


Instruction: What is the comparative advantage of lower- to higher-grade ECGs?

Output: reasonable cost, commensu-rate with accepted values for cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the comparative advantage of lower- to higher-grade ECGs?. ### Response: reasonable cost, commensu-rate with accepted values for cost effectiveness.


Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e97monitoring for determining prevalent risk of chronic kidney dis-ease?

Output: the Ohasama study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e97monitoring for determining prevalent risk of chronic kidney dis-ease?. ### Response: the Ohasama study.


Instruction: What was the Ohasama study?

Output: Masked hypertension determined by self-measured blood pressure at home and chronic kidney disease in the Japanese general population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Ohasama study?. ### Response: Masked hypertension determined by self-measured blood pressure at home and chronic kidney disease in the Japanese general population.


Instruction: What did the Ohasama study look at?

Output: Masked hypertension determined by self-measured blood pressure at home and chronic kidney disease in the Japanese general population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Ohasama study look at?. ### Response: Masked hypertension determined by self-measured blood pressure at home and chronic kidney disease in the Japanese general population.


Instruction: What was the name of the study that looked at self-measured blood pressure at home and chronic kidney disease?

Output: Ohasama

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that looked at self-measured blood pressure at home and chronic kidney disease?. ### Response: Ohasama.


Instruction: What are the outcomes during treatment in hypertensive patients with CKD?

Output: achieved clinic and ambulatory blood pressure recordings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes during treatment in hypertensive patients with CKD?. ### Response: achieved clinic and ambulatory blood pressure recordings.


Instruction: What is the name of the multicenter prospective cohort study?

Output: Assessment of achieved clinic and ambulatory blood pressure recordings and outcomes during treatment in hypertensive patients with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter prospective cohort study?. ### Response: Assessment of achieved clinic and ambulatory blood pressure recordings and outcomes during treatment in hypertensive patients with CKD.


Instruction: When was the Am J Kidney Dis.64:744–52?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Kidney Dis.64:744–52?. ### Response: 2014.


Instruction: What does target organ damage do?

Output: Masked hypertension and elevated nighttime blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does target organ damage do?. ### Response: Masked hypertension and elevated nighttime blood pressure.


Instruction: What does Agarwal R, Andersen MJ, and Navaneethan SD, Schold JD, Arrigain S, et al. do in non-dialysis dependent CKD?

Output: Cause-specific deaths

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Agarwal R, Andersen MJ, and Navaneethan SD, Schold JD, Arrigain S, et al. do in non-dialysis dependent CKD?. ### Response: Cause-specific deaths.


Instruction: How many deaths in non-dialysis-dependent CKD are there?

Output: S9.3-25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths in non-dialysis-dependent CKD are there?. ### Response: S9.3-25.


Instruction: What is the association between estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts?

Output: a collabora-tive meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts?. ### Response: a collabora-tive meta-analysis.


Instruction: What is the acronym for Chronic Kidney Disease Prognosis Consortium?

Output: Chronic Kidney Disease Prognosis Consortium. Lancet. 2010;375:2073–81. S9.3-26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Chronic Kidney Disease Prognosis Consortium?. ### Response: Chronic Kidney Disease Prognosis Consortium. Lancet. 2010;375:2073–81. S9.3-26.


Instruction: When was the Lancet 375:2073-81 published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet 375:2073-81 published?. ### Response: 2010.


Instruction: What was the name of the randomized trial of intensive versus standard blood-pressure control?

Output: SPRINT Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the randomized trial of intensive versus standard blood-pressure control?. ### Response: SPRINT Research Group.


Instruction: What is the name of the study group that studied the effects of intensive blood pressure control in type 2 diabetes mellitus?

Output: ACCORD Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studied the effects of intensive blood pressure control in type 2 diabetes mellitus?. ### Response: ACCORD Study Group.


Instruction: What is a 2013 ACC/AHA guideline on the assessment of cardiovascular risk?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 2013 ACC/AHA guideline on the assessment of cardiovascular risk?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines report on?

Output: assessment of cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines report on?. ### Response: assessment of cardiovascular risk.


Instruction: What is the name of the group that compiled a report on the risk of BP in patients with incident CKD?

Output: Clin J Am Soc Nephrol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that compiled a report on the risk of BP in patients with incident CKD?. ### Response: Clin J Am Soc Nephrol.


Instruction: What is the systolic BP and mortality in older adults with CKD?

Output: 1553–9. S9.3-31

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic BP and mortality in older adults with CKD?. ### Response: 1553–9. S9.3-31.


Instruction: What is Intensive vs standard blood pressure control and cardiovascular disease?

Output: A randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Intensive vs standard blood pressure control and cardiovascular disease?. ### Response: A randomized trial.


Instruction: What is the name of the randomized clinical trial that compared intensive vs standard blood pressure control and cardiovascular disease out-comes in adults aged  75 years?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial that compared intensive vs standard blood pressure control and cardiovascular disease out-comes in adults aged  75 years?. ### Response: JAMA.


Instruction: When was the JAMA 315:2673-82 published?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA 315:2673-82 published?. ### Response: 2016.


Instruction: What predicts a slower decrease in cardiovascular disease in adults treated with losartan?

Output: acute fall in estimated glomerular filtration rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts a slower decrease in cardiovascular disease in adults treated with losartan?. ### Response: acute fall in estimated glomerular filtration rate.


Instruction: What predicts a slower decrease in long-term renal function?

Output: An acute fall in estimated glomerular filtration rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts a slower decrease in long-term renal function?. ### Response: An acute fall in estimated glomerular filtration rate.


Instruction: What is the acronym for the Conference on Guideline Standardization?

Output: COGS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Conference on Guideline Standardization?. ### Response: COGS.


Instruction: What is included in the KDIGO Clinical Practice Guideline for LipidManagement?

Output: release date, status (original, revised, updated), and printand electronic sources

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in the KDIGO Clinical Practice Guideline for LipidManagement?. ### Response: release date, status (original, revised, updated), and printand electronic sources.


Instruction: What type of sources are used for guideline development?

Output: provider types, patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of sources are used for guideline development?. ### Response: provider types, patients.


Instruction: What are the primary disease/condition and intervention/service/technology that the guideline addresses?

Output: CKD and dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the primary disease/condition and intervention/service/technology that the guideline addresses?. ### Response: CKD and dyslipidemia.


Instruction: What is another name for non-dialysis-dependent or dialysis?

Output: CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for non-dialysis-dependent or dialysis?. ### Response: CKD.


Instruction: What is the goal that following the guideline is expected to achieve?

Output: development of a guideline on this topic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal that following the guideline is expected to achieve?. ### Response: development of a guideline on this topic.


Instruction: Who is this guideline intended to assist?

Output: the practitioner caring forpatients with CKD and dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is this guideline intended to assist?. ### Response: the practitioner caring forpatients with CKD and dyslipidemia.


Instruction: What is intended to assist the practitioner caring forpatients with CKD and dyslipidemia?

Output: This CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is intended to assist the practitioner caring forpatients with CKD and dyslipidemia?. ### Response: This CPG.


Instruction: What is the goal audience?

Output: practicing nephrologists and otherhealthcare providers for adults and children with CKD anddyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal audience?. ### Response: practicing nephrologists and otherhealthcare providers for adults and children with CKD anddyslipidemia.


Instruction: Who is the target audience for the guideline?

Output: practicing nephrologists and otherhealthcare providers for adults and children with CKD anddyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the target audience for the guideline?. ### Response: practicing nephrologists and otherhealthcare providers for adults and children with CKD anddyslipidemia.


Instruction: What are the patients eligible for guidelinerecommendations and list any exclusion criteria?

Output: Adults and children with CKD and dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the patients eligible for guidelinerecommendations and list any exclusion criteria?. ### Response: Adults and children with CKD and dyslipidemia.


Instruction: What is the name of the organization responsible for developing the guideline?

Output: Developer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization responsible for developing the guideline?. ### Response: Developer.


Instruction: What are the names/credentials/potentialconflicts of interest of individuals involved in theguideline's development?

Output: KDIGONames

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names/credentials/potentialconflicts of interest of individuals involved in theguideline's development?. ### Response: KDIGONames.


Instruction: Who is the funding source/sponsor and describe its role?

Output: Identify the funding source/sponsor and describe its rolein developing and/or reporting the guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the funding source/sponsor and describe its role?. ### Response: Identify the funding source/sponsor and describe its rolein developing and/or reporting the guideline.


Instruction: What is the name of the organization that supports KDIGO?

Output: Abbott, Amgen, Bayer Schering Pharma, Belo Foundation,Bristol-Myers Squibb, Chugai Pharmaceutical, Coca-ColaCompany, Dole Food Company, Fresenius Medical Care,Genzyme, Hoffmann-LaRoche, International Society ofNephrology, JC Penney, Kyowa Hakko Kirin, NATCO—TheOrganization for Transplant Professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that supports KDIGO?. ### Response: Abbott, Amgen, Bayer Schering Pharma, Belo Foundation,Bristol-Myers Squibb, Chugai Pharmaceutical, Coca-ColaCompany, Dole Food Company, Fresenius Medical Care,Genzyme, Hoffmann-LaRoche, International Society ofNephrology, JC Penney, Kyowa Hakko Kirin, NATCO—TheOrganization for Transplant Professionals.


Instruction: What are the names of the companies that support the initiative?

Output: Abbott, Amgen, Bayer Schering Pharma, Belo Foundation,Bristol-My

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the companies that support the initiative?. ### Response: Abbott, Amgen, Bayer Schering Pharma, Belo Foundation,Bristol-My.


Instruction: Who is the sponsor of the initiative called?

Output: Abbott, Amgen, Bayer Schering Pharma, Belo Foundation,Bristol-Myers Squib

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the sponsor of the initiative called?. ### Response: Abbott, Amgen, Bayer Schering Pharma, Belo Foundation,Bristol-Myers Squib.


Instruction: What does NATCO stand for?

Output: TheOrganization for Transplant Professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NATCO stand for?. ### Response: TheOrganization for Transplant Professionals.


Instruction: What is not accepted for the development or reporting of specific guidelines?

Output: funding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not accepted for the development or reporting of specific guidelines?. ### Response: funding.


Instruction: Who could participate in open review?

Output: All stakeholders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who could participate in open review?. ### Response: All stakeholders.


Instruction: What could all stakeholders participate in open review?

Output: 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could all stakeholders participate in open review?. ### Response: 8.


Instruction: What are the methods used to search the scientific literature?

Output: Evidence collection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the methods used to search the scientific literature?. ### Response: Evidence collection.


Instruction: People wit hout h yper tension.

Output: The y also had concerns about t he relevance of t he study design

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People wit hout h yper tension.. ### Response: The y also had concerns about t he relevance of t he study design.


Instruction: People had concerns about t he relevance of what?

Output: study design

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People had concerns about t he relevance of what?. ### Response: study design.


Instruction: The committee w ere also awar e of which data?

Output: trial data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee w ere also awar e of which data?. ### Response: trial data.


Instruction: How many diabetics wit h fewer additional risk f actors?

Output: type  2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many diabetics wit h fewer additional risk f actors?. ### Response: type  2.


Instruction: The committee agreed that t here was insufficient evidence to recommend a diff erent blood pr essur e tar get f or what subgr oup?

Output: adult s under 80 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee agreed that t here was insufficient evidence to recommend a diff erent blood pr essur e tar get f or what subgr oup?. ### Response: adult s under 80 years.


Instruction: What was not covered by other NICE guidelines?

Output: people wit h later-stage chr onic kidne y disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not covered by other NICE guidelines?. ### Response: people wit h later-stage chr onic kidne y disease.


Instruction: What was unclear and insufficient to det ermine whet her a lo wer tar get?

Output: evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was unclear and insufficient to det ermine whet her a lo wer tar get?. ### Response: evidence.


Instruction: What did ermine whet her a lo wer tar get w ould be beneficial and outweigh t he associat ed harms?

Output: based on clinic blood pr essur e, HBPM or ABPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did ermine whet her a lo wer tar get w ould be beneficial and outweigh t he associat ed harms?. ### Response: based on clinic blood pr essur e, HBPM or ABPM.


Instruction: What was the 2011 clinic blood pr essur e get of?

Output: 140/90  mmHg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2011 clinic blood pr essur e get of?. ### Response: 140/90  mmHg.


Instruction: Who was r etained and applies t o people wit h type 2 diabet es?

Output: the 2011 clinic blood pr essur e tar get of 140/90  mmHg f or adult s under 80 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was r etained and applies t o people wit h type 2 diabet es?. ### Response: the 2011 clinic blood pr essur e tar get of 140/90  mmHg f or adult s under 80 years.


Instruction: What were HBPM and ABPM retained at 135/85 mmHg?

Output: tar gets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were HBPM and ABPM retained at 135/85 mmHg?. ### Response: tar gets.


Instruction: What were also retained at 135/85 mmHg?

Output: ABPM) tar gets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were also retained at 135/85 mmHg?. ### Response: ABPM) tar gets.


Instruction: What emphasises the impor tance of achieving and maintaining a le vel consist ently belo w the person's blood pr essur e?

Output: r ecommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What emphasises the impor tance of achieving and maintaining a le vel consist ently belo w the person's blood pr essur e?. ### Response: r ecommendations.


Instruction: HBPM or ABPM can be based on what?

Output: clinic blood pr essur e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HBPM or ABPM can be based on what?. ### Response: clinic blood pr essur e.


Instruction: What are people wit h postural hypotension at risk of?

Output: adv erse e vents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are people wit h postural hypotension at risk of?. ### Response: adv erse e vents.


Instruction: What type of blood pr essur e is used f or monitoring?

Output: standing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of blood pr essur e is used f or monitoring?. ### Response: standing.


Instruction: Why would t his measur ement w ould o verestimat e daytime blood pre sur e and result in a vertreatment?

Output: people wit h postural hypot ension ar e at risk of adv erse e vents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why would t his measur ement w ould o verestimat e daytime blood pre sur e and result in a vertreatment?. ### Response: people wit h postural hypot ension ar e at risk of adv erse e vents.


Instruction: What is a patient wit h a sitting syst olic blood pr sessur?

Output: type  2 diabet es

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a patient wit h a sitting syst olic blood pr sessur?. ### Response: type  2 diabet es.


Instruction: What might a sitting syst olic blood pr essur e of 140 mmHg have when standing?

Output: a much lo wer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might a sitting syst olic blood pr essur e of 140 mmHg have when standing?. ### Response: a much lo wer.


Instruction: What might ha ve a much lo wer blood pr osessure e when standing and be at an incr eased risk of f alls if tr eated?

Output: a patient wit h a sitting syst olic blood pr essur e of 140 mmHg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might ha ve a much lo wer blood pr osessure e when standing and be at an incr eased risk of f alls if tr eated?. ### Response: a patient wit h a sitting syst olic blood pr essur e of 140 mmHg.


Instruction: How many groups are at risk of postural hypotension?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many groups are at risk of postural hypotension?. ### Response: 3.


Instruction: People o ver 80 years, with type 2 diabetes and wit h sympt oms of what?

Output: postural h ypot ension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People o ver 80 years, with type 2 diabetes and wit h sympt oms of what?. ### Response: postural h ypot ension.


Instruction: What should diabet es and wit h sympt oms have?

Output: fewer additional risk f actors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should diabet es and wit h sympt oms have?. ### Response: fewer additional risk f actors.


Instruction: What should t heir tr eatment be modified accor dingly if they have postural hypot ension?

Output: pot ension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should t heir tr eatment be modified accor dingly if they have postural hypot ension?. ### Response: pot ension.


Instruction: The standing blood pr ssur e should be used f or what?

Output: futur e monit oring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The standing blood pr ssur e should be used f or what?. ### Response: futur e monit oring.


Instruction: What should be used f or futur e monit oring?

Output: The standing blood pr essur e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used f or futur e monit oring?. ### Response: The standing blood pr essur e.


Instruction: What should the r ecommendations curr ent?

Output: good practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the r ecommendations curr ent?. ### Response: good practice.


Instruction: What could lead to a higher use of antih yper tensiv e drugs and an incr ease in consultations?

Output: blood pr essur e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could lead to a higher use of antih yper tensiv e drugs and an incr ease in consultations?. ### Response: blood pr essur e.


Instruction: How do people with type 2 diabetics maintain tar get blood pr essur e?

Output: based on clinic blood pr essur e, HBPM or ABPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do people with type 2 diabetics maintain tar get blood pr essur e?. ### Response: based on clinic blood pr essur e, HBPM or ABPM.


Instruction: What is t he slight ly higher?

Output: tar get blood pr essur e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he slight ly higher?. ### Response: tar get blood pr essur e.


Instruction: What does blood pr essur e compar ed to reduce?

Output: adverse e vents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does blood pr essur e compar ed to reduce?. ### Response: adverse e vents.


Instruction: What does hyper tension in adult s: diagnosis and management (NG136) lead to?

Output: fewer appointment s and r educed drug use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does hyper tension in adult s: diagnosis and management (NG136) lead to?. ### Response: fewer appointment s and r educed drug use.


Instruction: What is the name of the book that discusses the diagnosis of heart failure?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that discusses the diagnosis of heart failure?. ### Response: Chronic Heart Failure.


Instruction: Who is the author?

Output: Zaphiriou

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author?. ### Response: Zaphiriou.


Instruction: What is the name of the cardiologist who assessed the ESC criteria for heart failure?

Output: Zuber

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the cardiologist who assessed the ESC criteria for heart failure?. ### Response: Zuber.


Instruction: What was the average age of people with suspected heart failure in 2012?

Output: 65

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the average age of people with suspected heart failure in 2012?. ### Response: 65.


Instruction: How old was the median age in the UK in 2012359?

Output: 220

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old was the median age in the UK in 2012359?. ### Response: 220.


Instruction: In what year did Verdu release Verdu?

Output: UK Verdu 2012359

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Verdu release Verdu?. ### Response: UK Verdu 2012359.


Instruction: Who assessed the ESC criteria?

Output: Zuber

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who assessed the ESC criteria?. ### Response: Zuber.


Instruction: How many people had suspected heart failure based on new symptoms?

Output: 74

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people had suspected heart failure based on new symptoms?. ### Response: 74.


Instruction: What is the median age of people with heart failure?

Output: 74

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the median age of people with heart failure?. ### Response: 74.


Instruction: Who assessed heart failure BNP NT-proBNP?

Output: one of seven cardiologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who assessed heart failure BNP NT-proBNP?. ### Response: one of seven cardiologists.


Instruction: Who assessed the BNP NT-proBNP ESC criteria?

Output: Zuber

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who assessed the BNP NT-proBNP ESC criteria?. ### Response: Zuber.


Instruction: How many people had suspected heart failure based on symptoms and clinical examination?

Output: 384

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people had suspected heart failure based on symptoms and clinical examination?. ### Response: 384.


Instruction: What gender was assessed by a single cardiologist?

Output: 130:176

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What gender was assessed by a single cardiologist?. ### Response: 130:176.


Instruction: How many cardiologists assessed Heart failure BNP NT-proBNP?

Output: seven

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cardiologists assessed Heart failure BNP NT-proBNP?. ### Response: seven.


Instruction: How many heart failure symptoms/signs were present?

Output: 74

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many heart failure symptoms/signs were present?. ### Response: 74.


Instruction: What is the EF  50%?

Output: < 50%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the EF  50%?. ### Response: < 50%,.


Instruction: How many cardiologists are there?

Output: seven

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cardiologists are there?. ### Response: seven.


Instruction: What is the risk of bias?

Output: Very high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of bias?. ### Response: Very high.


Instruction: 4.3 Identifying and analysing e vidence of effectiveness Research fellows conducted the tasks listed below which are described in more detail in the rest of this section?

Output:  Identified p otentially relevant studies for each review question from the releva nt search results by reviewing titles and abstracts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 4.3 Identifying and analysing e vidence of effectiveness Research fellows conducted the tasks listed below which are described in more detail in the rest of this section?. ### Response:  Identified p otentially relevant studies for each review question from the releva nt search results by reviewing titles and abstracts.


Instruction: What did researchers review from the releva nt search results?

Output: titles and abstracts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did researchers review from the releva nt search results?. ### Response: titles and abstracts.


Instruction: What criteria were used to identify studies that addressed the review question in the appropriate population?

Output: prespecified inclusion and exclusion criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria were used to identify studies that addressed the review question in the appropriate population?. ### Response: prespecified inclusion and exclusion criteria.


Instruction: What is included in appendix A?

Output: review protocols

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in appendix A?. ### Response: review protocols.


Instruction: What is the incidence of ventricular arrhythmias among patients with acute coronary syndromes with no ST-segment elevation?

Output: Sustained ventricular arrhythmias among patients with acute coronary syndromes with no ST-segment elevation: incidence, predictors, and outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence of ventricular arrhythmias among patients with acute coronary syndromes with no ST-segment elevation?. ### Response: Sustained ventricular arrhythmias among patients with acute coronary syndromes with no ST-segment elevation: incidence, predictors, and outcomes.


Instruction: What are the incidence, predictors, and outcomes?

Output: Sustained ventricular arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the incidence, predictors, and outcomes?. ### Response: Sustained ventricular arrhythmias.


Instruction: When was Circulation. 2002;106:309-12?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation. 2002;106:309-12?. ### Response: 2002.


Instruction: What is ventricular fibrillation before primary angioplasty in patients with first ST-elevation myocardial infarction?

Output: Incidence and risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ventricular fibrillation before primary angioplasty in patients with first ST-elevation myocardial infarction?. ### Response: Incidence and risk factors.


Instruction: What is the name of the nationwide study in Denmark?

Output: J Am Heart Assoc.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the nationwide study in Denmark?. ### Response: J Am Heart Assoc..


Instruction: What is tachycardia called in patients undergoing primary percutaneous coronary intervention?

Output: fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tachycardia called in patients undergoing primary percutaneous coronary intervention?. ### Response: fibrillation.


Instruction: What is the name of the GISSI investigators?

Output: Gruppo Italiano per lo Studio della Streptochinasi nell’Infarto miocardico

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the GISSI investigators?. ### Response: Gruppo Italiano per lo Studio della Streptochinasi nell’Infarto miocardico.


Instruction: How long does it take to diagnose primary ventricular fibrillation?

Output: One-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to diagnose primary ventricular fibrillation?. ### Response: One-year.


Instruction: What is nell'Infarto miocardico) investigators?

Output: GISSI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is nell'Infarto miocardico) investigators?. ### Response: GISSI.


Instruction: What is El-Sherif N, Smith RA, Evans K. Canine ventricular arrhythmias in the late myocardial infarction period?

Output: Epicardial mapping of reentrant circuits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is El-Sherif N, Smith RA, Evans K. Canine ventricular arrhythmias in the late myocardial infarction period?. ### Response: Epicardial mapping of reentrant circuits.


Instruction: Epicardial mapping of what?

Output: reentrant circuits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Epicardial mapping of what?. ### Response: reentrant circuits.


Instruction: What is the status of genetic testing for the channelopathies and cardiomyopathies?

Output: HRS/EHRA expert consen-sus statement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the status of genetic testing for the channelopathies and cardiomyopathies?. ### Response: HRS/EHRA expert consen-sus statement.


Instruction: What was developed as a partner-ship between the Heart Rhythm Society and the EHRA?

Output: HRS/EHRA expert consen-sus statement on the state of genetic testing for the channelopathies and cardiomyopathies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed as a partner-ship between the Heart Rhythm Society and the EHRA?. ### Response: HRS/EHRA expert consen-sus statement on the state of genetic testing for the channelopathies and cardiomyopathies.