Instruction: What was the RR of fatal stroke?

Output: 2.03

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of fatal stroke?. ### Response: 2.03.


Instruction: What is the secondary endpoint of combined cardiacevents?

Output: RR 0.82

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the secondary endpoint of combined cardiacevents?. ### Response: RR 0.82.


Instruction: How many HDpatients were assigned to receive rosuvastatin 10 mg daily orplacebo?

Output: 2776

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many HDpatients were assigned to receive rosuvastatin 10 mg daily orplacebo?. ### Response: 2776.


Instruction: How long was the median follow-up on orplacebo?

Output: 4.9 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the median follow-up on orplacebo?. ### Response: 4.9 years.


Instruction: What was the themean reduction in LDL-C in the intervention group?

Output: 43%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the themean reduction in LDL-C in the intervention group?. ### Response: 43%.


Instruction: The combined primary endpoint of death from cardiovascularcauses, nonfatal MI, or what else was not reduced?

Output: nonfatal stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The combined primary endpoint of death from cardiovascularcauses, nonfatal MI, or what else was not reduced?. ### Response: nonfatal stroke.


Instruction: Rosuvastatin did notreduce the risk of what?

Output: individual components of the primaryendpoint

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Rosuvastatin did notreduce the risk of what?. ### Response: individual components of the primaryendpoint.


Instruction: What was the HR of rosuvastatin?

Output: 0.96

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of rosuvastatin?. ### Response: 0.96.


Instruction: What is SHARP?

Output: Study of Heart and Renal Protection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SHARP?. ### Response: Study of Heart and Renal Protection.


Instruction: How many participants were assigned to a study of heart and renal protection?

Output: 9270

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants were assigned to a study of heart and renal protection?. ### Response: 9270.


Instruction: What was the mean reduction in LDL-Camong the treatment group?

Output: 0.83 mmol/l

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean reduction in LDL-Camong the treatment group?. ### Response: 0.83 mmol/l.


Instruction: What percentage of patients were receiving maintenance dialysis at randomization?

Output: Thirty-three percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients were receiving maintenance dialysis at randomization?. ### Response: Thirty-three percent.


Instruction: How many CKD patients had amean eGFR of 27 ml/min/1.73 m2?

Output: 6247

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many CKD patients had amean eGFR of 27 ml/min/1.73 m2?. ### Response: 6247.


Instruction: What was the reduction in LDL-Camong the treatment group?

Output: 0.83 mmol/l

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in LDL-Camong the treatment group?. ### Response: 0.83 mmol/l.


Instruction: Statin plus ezetimibe therapy was associated with a significant 17% RR reduction of theprimary outcome of major atherosclerotic events?

Output: death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Statin plus ezetimibe therapy was associated with a significant 17% RR reduction of theprimary outcome of major atherosclerotic events?. ### Response: death.


Instruction: What did SHARP indicate was reduced by simvastatin/ezetimibe among a wide range of patients with CKD?

Output: risk for the primary outcome of majoratherosclerotic events other than death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did SHARP indicate was reduced by simvastatin/ezetimibe among a wide range of patients with CKD?. ### Response: risk for the primary outcome of majoratherosclerotic events other than death.


Instruction: What did combination treatment not significantly reduce in the subgroup of over 3000patients treated with dialysis at the same time?

Output: risk of the primary outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did combination treatment not significantly reduce in the subgroup of over 3000patients treated with dialysis at the same time?. ### Response: risk of the primary outcome.


Instruction: How many patients were treated with dialysis at baseline?

Output: over 3000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with dialysis at baseline?. ### Response: over 3000.


Instruction: A systematic review pooling data from all available randomized trials done in CKD populations reported what?

Output: signiﬁcant heterogeneity between dialysis and non-dialysispatients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A systematic review pooling data from all available randomized trials done in CKD populations reported what?. ### Response: signiﬁcant heterogeneity between dialysis and non-dialysispatients.


Instruction: What is HR for non-dialysis?

Output: 0.76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HR for non-dialysis?. ### Response: 0.76.


Instruction: What is the clinical benefit of statins in prevalent dialysispatients?

Output: 17% RR reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical benefit of statins in prevalent dialysispatients?. ### Response: 17% RR reduction.


Instruction: What did meta-analysis in essence confirm?

Output: the results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did meta-analysis in essence confirm?. ### Response: the results.


Instruction: What is the magnitude of any relative reduction in risk?

Output: substantially276

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the magnitude of any relative reduction in risk?. ### Response: substantially276.


Instruction: What year was the Mayo Clinic STEMI Protocol published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the Mayo Clinic STEMI Protocol published?. ### Response: 2009.


Instruction: What is the name of the protocol used to optimize the timeliness of reperfusion therapy for ST-elevation myocardial infarction?

Output: Mayo Clinic STEMI Protocol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the protocol used to optimize the timeliness of reperfusion therapy for ST-elevation myocardial infarction?. ### Response: Mayo Clinic STEMI Protocol.


Instruction: What type of infarction causes H18546non-ST elevation?

Output: myocardial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of infarction causes H18546non-ST elevation?. ### Response: myocardial.


Instruction: What is the name of the infarct caused by myocardial infartion?

Output: H18546

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the infarct caused by myocardial infartion?. ### Response: H18546.


Instruction: When was this article published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 28, 2023.


Instruction: Where did this article appear?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did this article appear?. ### Response: http://ahajournals.org.


Instruction: What is the interaction between baseline eGFR and SBP lowering?

Output: patients with a baseline eGFR <45 ml/min per 1.73 m2had anincreased risk of AKI in the intensive BP arm but no reductionin the primary CV outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the interaction between baseline eGFR and SBP lowering?. ### Response: patients with a baseline eGFR <45 ml/min per 1.73 m2had anincreased risk of AKI in the intensive BP arm but no reductionin the primary CV outcome.


Instruction: What did patients with a baseline EGFR 45 ml/min per 1.73 m2 have an increased risk of in the intensive BP arm?

Output: AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients with a baseline EGFR 45 ml/min per 1.73 m2 have an increased risk of in the intensive BP arm?. ### Response: AKI.


Instruction: What may not be as favorable in the intensive SBP arm as in the subgroup with higherbaseline eGFR?

Output: the risk –beneﬁtr a t i of o rkidney outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not be as favorable in the intensive SBP arm as in the subgroup with higherbaseline eGFR?. ### Response: the risk –beneﬁtr a t i of o rkidney outcomes.


Instruction: What should be used in interpreting non-prespeci fiedpost hoc findings in relatively smallsubgroups?

Output: caution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used in interpreting non-prespeci fiedpost hoc findings in relatively smallsubgroups?. ### Response: caution.


Instruction: In 2 other post hoc analyses of SPRINT, therespective risks of what were found?

Output: AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 2 other post hoc analyses of SPRINT, therespective risks of what were found?. ### Response: AKI.


Instruction: What did post hoc analyses of SPRINT show?

Output: the number ofadditional BP-lowering medications was an independent pre-dictor of poorer survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did post hoc analyses of SPRINT show?. ### Response: the number ofadditional BP-lowering medications was an independent pre-dictor of poorer survival.


Instruction: What increased the risk of AKI in people 75 years old?

Output: intensive BP target

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increased the risk of AKI in people 75 years old?. ### Response: intensive BP target.


Instruction: What increased the risk of AKI in people with moderate CKD and advanced age?

Output: inten-sive BP lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increased the risk of AKI in people with moderate CKD and advanced age?. ### Response: inten-sive BP lowering.


Instruction: How many SPRINT participants were affected by episodes of BP lowering?

Output: less than 4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many SPRINT participants were affected by episodes of BP lowering?. ### Response: less than 4%.


Instruction: What were most participants in the study taking before randomization?

Output: 1 or 2BP-lowering therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were most participants in the study taking before randomization?. ### Response: 1 or 2BP-lowering therapies.


Instruction: How many BP-lowering therapies did patients in SPRINT take before randomization?

Output: 1 or 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many BP-lowering therapies did patients in SPRINT take before randomization?. ### Response: 1 or 2.


Instruction: What is unclear among patients who require 4 or more BP lowering medications to achieve SBP 120 mm Hg?

Output: The bene ﬁts ofintensive SBP lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unclear among patients who require 4 or more BP lowering medications to achieve SBP 120 mm Hg?. ### Response: The bene ﬁts ofintensive SBP lowering.


Instruction: In a post hoc analysis, the number of additional what was an independent pre-dictor of poorer?

Output: BP-lowering medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a post hoc analysis, the number of additional what was an independent pre-dictor of poorer?. ### Response: BP-lowering medications.


Instruction: What was an independent pre-dictor of poorer survival?

Output: the number ofadditional BP-lowering medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was an independent pre-dictor of poorer survival?. ### Response: the number ofadditional BP-lowering medications.


Instruction: The requirement for multiple medications to achieve SBP 120 mm Hg may re flect what?

Output: the patient ’s underlying characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The requirement for multiple medications to achieve SBP 120 mm Hg may re flect what?. ### Response: the patient ’s underlying characteristics.


Instruction: What did the addition of a new antihypertensive drug class lead to?

Output: reductionsin SBP and major CV event rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the addition of a new antihypertensive drug class lead to?. ### Response: reductionsin SBP and major CV event rates.


Instruction: What was the difference in serious adverse events in a study using the SPRINT database?

Output: no

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference in serious adverse events in a study using the SPRINT database?. ### Response: no.


Instruction: What did incremental effects appear to be consistent regardless of?

Output: the level of baseline drug use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did incremental effects appear to be consistent regardless of?. ### Response: the level of baseline drug use.


Instruction: At present, there is no clear evidence that people who require multiple medications to achieve an SBP of 120 mm Hg would have an unfavorable what?

Output: risk –beneﬁt ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At present, there is no clear evidence that people who require multiple medications to achieve an SBP of 120 mm Hg would have an unfavorable what?. ### Response: risk –beneﬁt ratio.


Instruction: What adds to treatment burden and is often?

Output: poly-pharmacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What adds to treatment burden and is often?. ### Response: poly-pharmacy.


Instruction: What adds to treatment burden and is often associated with reduced adherence?

Output: poly-pharmacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What adds to treatment burden and is often associated with reduced adherence?. ### Response: poly-pharmacy.


Instruction: What may be attenuated by the use of single-pill combinations?

Output: poly-pharmacy also adds to treatment burden and is often associatedwith reduced adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be attenuated by the use of single-pill combinations?. ### Response: poly-pharmacy also adds to treatment burden and is often associatedwith reduced adherence.


Instruction: The evidence on the effects of intensiveBP lowering is called what?

Output: Quality of evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The evidence on the effects of intensiveBP lowering is called what?. ### Response: Quality of evidence.


Instruction: What is considered to be moderate due to study limitations?

Output: CV events and all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered to be moderate due to study limitations?. ### Response: CV events and all-cause mortality.


Instruction: What is the effect on kidney failure?

Output: weak

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect on kidney failure?. ### Response: weak.


Instruction: Where is the evidence for CV events and all-cause mortality derived?

Output: SPRINT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the evidence for CV events and all-cause mortality derived?. ### Response: SPRINT.


Instruction: How many years after the Duke criteria did Bayer re-visit his criteria for endocarditis?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years after the Duke criteria did Bayer re-visit his criteria for endocarditis?. ### Response: two.


Instruction: What is the name of the journal that published a study on Duke criteria in 1993?

Output: Dis Clin North Am

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published a study on Duke criteria in 1993?. ### Response: Dis Clin North Am.


Instruction: How many patients were diagnosed with Duke's criteria in 1996?

Output: 23:303–4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were diagnosed with Duke's criteria in 1996?. ### Response: 23:303–4.


Instruction: Where can you find a copy of Bayer's study?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find a copy of Bayer's study?. ### Response: http://ahajournals.org.


Instruction: How many years later did the criteria come to be?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years later did the criteria come to be?. ### Response: two.


Instruction: What is the name of the journal that was downloaded from http://ahajournals.org?

Output: Clin Infect Dis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that was downloaded from http://ahajournals.org?. ### Response: Clin Infect Dis.


Instruction: What is a CLASS III: HARM?

Output: Long-term use of either continuous or intermittent, intrave-nous parenteral positive inotropic agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a CLASS III: HARM?. ### Response: Long-term use of either continuous or intermittent, intrave-nous parenteral positive inotropic agents.


Instruction: What is the risk of long-term use of parenteral positive inotropic agents?

Output: potentially harmful

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of long-term use of parenteral positive inotropic agents?. ### Response: potentially harmful.


Instruction: What is a potential danger of parenteral inotropic agents in hospitalized patients?

Output: end-organ performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential danger of parenteral inotropic agents in hospitalized patients?. ### Response: end-organ performance.


Instruction: What is the level of evidence of?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence of?. ### Response: B.


Instruction: What is the dose of HFInotropic Agent?

Output: mcg/kg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the dose of HFInotropic Agent?. ### Response: mcg/kg.


Instruction: What are some of the special considerations for Bolus Infusion?

Output: Adverse Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the special considerations for Bolus Infusion?. ### Response: Adverse Effects.


Instruction: How long does it take for Dopamine N/A to reach its maximum?

Output: 2 to 20 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for Dopamine N/A to reach its maximum?. ### Response: 2 to 20 min.


Instruction: How long does it take to do Milrinone N/R 0.125 to 0.75?

Output: 2 to 3 minH[[Y4 [ /YBP, HA, T, N, F,hypersensitivityCaution: MAO-I;CI: sulﬁte allergyN/A 5 to 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to do Milrinone N/R 0.125 to 0.75?. ### Response: 2 to 3 minH[[Y4 [ /YBP, HA, T, N, F,hypersensitivityCaution: MAO-I;CI: sulﬁte allergyN/A 5 to 20.


Instruction: What is the name of the drug that is used to treat hypersensitivity?

Output: MAO-I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat hypersensitivity?. ### Response: MAO-I.


Instruction: CO, cardiac output; F, fever; H, hepatic; HF, heart failure; LFT, liver function test; MAO-I, what?

Output: monoamine oxidase inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CO, cardiac output; F, fever; H, hepatic; HF, heart failure; LFT, liver function test; MAO-I, what?. ### Response: monoamine oxidase inhibitor.


Instruction: PDE, phosphodiesterase; PVR, pulmonary vascular resistance; R, renal; SVR, systemic vascular resistant; and t 1/2, elimination half-life?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PDE, phosphodiesterase; PVR, pulmonary vascular resistance; R, renal; SVR, systemic vascular resistant; and t 1/2, elimination half-life?. ### Response: [[.


Instruction: What is the acronym for systemic vascular resistance?

Output: SVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for systemic vascular resistance?. ### Response: SVR.


Instruction: What is t 1/2?

Output: elimination half-life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t 1/2?. ### Response: elimination half-life.


Instruction: How long is the elimination half-life?

Output: t 1/2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the elimination half-life?. ### Response: t 1/2.


Instruction: What type of intravenous use is potentially harmful in stage DHFIII: Harm B 172,283–288Short-term intravenous use in hospitalized patients with stage D and severe HF rEFIIb B 277–279Long-term support with continuous infusion palliative therapy in select stage D HF IIb B 280–282Routine intravennous use, either continuous or intermittent, is potential harmful in what stage?

Output: continuous or intermittent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intravenous use is potentially harmful in stage DHFIII: Harm B 172,283–288Short-term intravenous use in hospitalized patients with stage D and severe HF rEFIIb B 277–279Long-term support with continuous infusion palliative therapy in select stage D HF IIb B 280–282Routine intravennous use, either continuous or intermittent, is potential harmful in what stage?. ### Response: continuous or intermittent.


Instruction: What is potentially harmful in stage D HFIII: Harm B 172,283–288Nondurable MCS is beneficial in carefully selected *patients with stage DHF in whom definitivemanagement (e.g., cardiac transplantation) is anticipated or planned?

Output: Short-term intravenous use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is potentially harmful in stage D HFIII: Harm B 172,283–288Nondurable MCS is beneficial in carefully selected *patients with stage DHF in whom definitivemanagement (e.g., cardiac transplantation) is anticipated or planned?. ### Response: Short-term intravenous use.


Instruction: What is reasonable as a “bridge to recovery”?

Output: Nondurable MCS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable as a “bridge to recovery”?. ### Response: Nondurable MCS.


Instruction: What does nondurable MCS prolong for carefully selected patients?

Output: reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does nondurable MCS prolong for carefully selected patients?. ### Response: reasonable.


Instruction: What is indicated for carefully selected patients with stage D HF despite GDMT, device and surgical management?

Output: Evaluation for cardiac transplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated for carefully selected patients with stage D HF despite GDMT, device and surgical management?. ### Response: Evaluation for cardiac transplantation.


Instruction: What is the name of the product that is used to treat stroke?

Output: angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the product that is used to treat stroke?. ### Response: angina.


Instruction: What is one of the outcomes of interest for stroke prevention?

Output: secondary NEXT/1 prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the outcomes of interest for stroke prevention?. ### Response: secondary NEXT/1 prevention.


Instruction: What is an example of an art infarction?

Output: unstable angina pectoris

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an art infarction?. ### Response: unstable angina pectoris.


Instruction: What is another example of a heart NEXT/1 attack?

Output: ti,ab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another example of a heart NEXT/1 attack?. ### Response: ti,ab.


Instruction: What is another word for morbidity OR mortality OR prevent* OR outcome*?

Output: morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another word for morbidity OR mortality OR prevent* OR outcome*?. ### Response: morbidity.


Instruction: What is the other word for primary NEXT/1 prevention?

Output: ti,ab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the other word for primary NEXT/1 prevention?. ### Response: ti,ab.


Instruction: What does the Task Force strive to avoid by selecting experts from a broad array of back-grounds representing differe nt geographic regions, sexes, and ethnicities?

Output: bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Task Force strive to avoid by selecting experts from a broad array of back-grounds representing differe nt geographic regions, sexes, and ethnicities?. ### Response: bias.


Instruction: What types of perspectives/biases are there in clinical practice?

Output: intellec tual

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What types of perspectives/biases are there in clinical practice?. ### Response: intellec tual.


Instruction: What type of organizations and pro-fessional societies can be invited to participate as partners or collaborators?

Output: related interests and expertise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of organizations and pro-fessional societies can be invited to participate as partners or collaborators?. ### Response: related interests and expertise.


Instruction: What is bene fita n dh a r m?

Output: shared decision making between the patient and clini-cian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is bene fita n dh a r m?. ### Response: shared decision making between the patient and clini-cian.


Instruction: What does stan-dardized terminology mean for arti-culating recommendations?

Output: organizational involvement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does stan-dardized terminology mean for arti-culating recommendations?. ### Response: organizational involvement.


Instruction: How often are new data reviewed to ensure that guide-lines remain current?

Output: biannually

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often are new data reviewed to ensure that guide-lines remain current?. ### Response: biannually.


Instruction: How often are full revisions posted?

Output: 5-year cycles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often are full revisions posted?. ### Response: 5-year cycles.


Instruction: Who is a member of the ACC/AHA Task Force on Clinical Practice Guidelines?

Output: Jonathan L. Halperin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the ACC/AHA Task Force on Clinical Practice Guidelines?. ### Response: Jonathan L. Halperin.


Instruction: What is the term for multivessel percutaneous coronaryintervention?

Output: PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for multivessel percutaneous coronaryintervention?. ### Response: PCI.


Instruction: What is another term for ST-elevation myocardial infarction?

Output: STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for ST-elevation myocardial infarction?. ### Response: STEMI.


Instruction: When were the 2015 annual scientific meetings held?

Output: August 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were the 2015 annual scientific meetings held?. ### Response: August 2015.


Instruction: What was the purpose of the 2015 peer-reviewed meetings?

Output: to identifytrials and other key data that might affect guideline rec-ommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the purpose of the 2015 peer-reviewed meetings?. ### Response: to identifytrials and other key data that might affect guideline rec-ommendations.


Instruction: Who reviewed the 2015 reports?

Output: the 2011 PCIand 2013 STEMI GWCs and the Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reviewed the 2015 reports?. ### Response: the 2011 PCIand 2013 STEMI GWCs and the Task Force.


Instruction: What is included in evidence tables in the Online Data Supplement?

Output: The information considered importantenough to prompt updated recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in evidence tables in the Online Data Supplement?. ### Response: The information considered importantenough to prompt updated recommendations.


Instruction: What is important enough to prompt updated recommendations?

Output: information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important enough to prompt updated recommendations?. ### Response: information.


Instruction: What should patients be instructed to seek immediate medical evaluation for?

Output: fever

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients be instructed to seek immediate medical evaluation for?. ### Response: fever.


Instruction: What should be obtained (Class I; Level of Evidence C) for fever?

Output: blood cultures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be obtained (Class I; Level of Evidence C) for fever?. ### Response: blood cultures.


Instruction: What type of illness is undefined unless the patient’s condition warrants it?

Output: febrile

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of illness is undefined unless the patient’s condition warrants it?. ### Response: febrile.


Instruction: What is a class III; Level of Evidence C?

Output: Antimicrobial therapy should not be initiated for the treatment of undefined febrile illnesses unless the patient’s condition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class III; Level of Evidence C?. ### Response: Antimicrobial therapy should not be initiated for the treatment of undefined febrile illnesses unless the patient’s condition.


Instruction: A large, prospective study demonstrated a strong associa-tion between how many indexes of oral hygiene and gingival disease?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A large, prospective study demonstrated a strong associa-tion between how many indexes of oral hygiene and gingival disease?. ### Response: 3.


Instruction: Poor oral hygiene results in what?

Output: gingivitis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Poor oral hygiene results in what?. ### Response: gingivitis.


Instruction: What does poor oral hygiene result in?

Output: gingivitis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does poor oral hygiene result in?. ### Response: gingivitis.


Instruction: What often leads to periodontitis?

Output: gingivitis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What often leads to periodontitis?. ### Response: gingivitis.


Instruction: How many periodontal dis-eases are associated with community acquired IE?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many periodontal dis-eases are associated with community acquired IE?. ### Response: 2.


Instruction: What is likely to be responsible for the vast majority of cases of IE that originate in the mouth?

Output: poor oral hygiene and periodon-tal diseases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to be responsible for the vast majority of cases of IE that originate in the mouth?. ### Response: poor oral hygiene and periodon-tal diseases.


Instruction: Inpatients with IE should be thoroughly evaluated by a dentist familiar with what?

Output: the potential role of the mouth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inpatients with IE should be thoroughly evaluated by a dentist familiar with what?. ### Response: the potential role of the mouth.


Instruction: What is the optimal time for an evaluation of a patient?

Output: after the patient’s cardiac status has stabilized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the optimal time for an evaluation of a patient?. ### Response: after the patient’s cardiac status has stabilized.


Instruction: When should the patient's cardiac status stabilize?

Output: after

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should the patient's cardiac status stabilize?. ### Response: after.


Instruction: What should be ruled out?

Output: periodontal inflammation and pocketing around the teeth and caries that will eventually result in pulpal infection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be ruled out?. ### Response: periodontal inflammation and pocketing around the teeth and caries that will eventually result in pulpal infection.


Instruction: What will eventually result in pulpal infection?

Output: periodontal inflammation and pocketing around the teeth and caries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will eventually result in pulpal infection?. ### Response: periodontal inflammation and pocketing around the teeth and caries.


Instruction: A full series of intra-oral radiographs is required for the identification of what?

Output: caries and periodontal disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A full series of intra-oral radiographs is required for the identification of what?. ### Response: caries and periodontal disease.


Instruction: What is the goal of the treatment?

Output: reducing the incidence and magnitude of bactere-mia from any manipulation of the gingival tissues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of the treatment?. ### Response: reducing the incidence and magnitude of bactere-mia from any manipulation of the gingival tissues.


Instruction: What is a daily event that can cause bactere-mia?

Output: brushing teeth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a daily event that can cause bactere-mia?. ### Response: brushing teeth.


Instruction: Who will review with patients the importance of maintaining scrupulous oral hygiene?

Output: hygienist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who will review with patients the importance of maintaining scrupulous oral hygiene?. ### Response: hygienist.


Instruction: What is almost entirely preventable if patients are compliant with 4 measures?

Output: Dental disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is almost entirely preventable if patients are compliant with 4 measures?. ### Response: Dental disease.


Instruction: What is the cause of both peri-odontal disease and caries?

Output: bacterial plaque accumulation on teeth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of both peri-odontal disease and caries?. ### Response: bacterial plaque accumulation on teeth.


Instruction: What is dependent on keeping teeth free of plaque?

Output: prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is dependent on keeping teeth free of plaque?. ### Response: prevention.


Instruction: What are dietary mea-sures critical in preventing the formation of?

Output: plaque

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are dietary mea-sures critical in preventing the formation of?. ### Response: plaque.


Instruction: How are sugar and other refined carbohydrates eliminated from the diet?

Output: The degree

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are sugar and other refined carbohydrates eliminated from the diet?. ### Response: The degree.


Instruction: What type of carbohydrates are eliminated from the diet will have a major impact on the growth of pathogenic bacteria species?

Output: sugar and other refined carbohydrates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of carbohydrates are eliminated from the diet will have a major impact on the growth of pathogenic bacteria species?. ### Response: sugar and other refined carbohydrates.


Instruction: Routine follow-up with their family dentist is necessary for close monitoring of what?

Output: oral hygiene

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Routine follow-up with their family dentist is necessary for close monitoring of what?. ### Response: oral hygiene.


Instruction: What can be done to prevent oral disease?

Output: if patients are compliant with 4 measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be done to prevent oral disease?. ### Response: if patients are compliant with 4 measures.


Instruction: What type of toothpaste should be used daily?

Output: high-concentration fluori-dated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of toothpaste should be used daily?. ### Response: high-concentration fluori-dated.


Instruction: What type of relationship does DCRI have?

Output: No financial relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of relationship does DCRI have?. ### Response: No financial relationship.


Instruction: What is the largest amount of a relationship?

Output: $10 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the largest amount of a relationship?. ### Response: $10 000.


Instruction: Who sponsors the grants and contracts?

Output: industry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who sponsors the grants and contracts?. ### Response: industry.


Instruction: What is the name of the pharmaceutical company that is a part of ANGES MG?

Output: Angiomedtrix

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pharmaceutical company that is a part of ANGES MG?. ### Response: Angiomedtrix.


Instruction: What is one of the major pharmaceutical companies in BG Medicine?

Output: Biogen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the major pharmaceutical companies in BG Medicine?. ### Response: Biogen.


Instruction: BMS Pfizer is a subsidiary of what company?

Output: Boehringer Ingelheim Biogen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BMS Pfizer is a subsidiary of what company?. ### Response: Boehringer Ingelheim Biogen.


Instruction: What is the name of the pharmaceutical company that is part of the CV Therapeutics group?

Output: Daiichi Pharmaceuticals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pharmaceutical company that is part of the CV Therapeutics group?. ### Response: Daiichi Pharmaceuticals.


Instruction: Who is the CEO of Eclipse Surgical Technologies?

Output: Dr. Reddy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the CEO of Eclipse Surgical Technologies?. ### Response: Dr. Reddy.


Instruction: Surgical Technologies; Edwards Lifesciences; Eisai; Endicor; EnteroMedics; Enzon Pharmaceuticals; Eli Lilly; Ethicon; Ev3; Evalve; F2G; Flow Cardia; Ikaria; Hoffman-LaRoche; Hospira; Genetech; Genzyme Corp.; Gilad Sciences; GlaxoSmithKline; Guidant Corp.

Output: *No financial relationship.†Significant (greater than $10 000) relationship.‡

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Surgical Technologies; Edwards Lifesciences; Eisai; Endicor; EnteroMedics; Enzon Pharmaceuticals; Eli Lilly; Ethicon; Ev3; Evalve; F2G; Flow Cardia; Ikaria; Hoffman-LaRoche; Hospira; Genetech; Genzyme Corp.; Gilad Sciences; GlaxoSmithKline; Guidant Corp.. ### Response: *No financial relationship.†Significant (greater than $10 000) relationship.‡.


Instruction: GlaxoSmithKline; Guidant Corp.; Heartscape Technologies; Ikaria; Imcor Pharmaceuticals; Inimex; Janssen; Johnson and Johnson; Juju Therapeutics; KAI Pharmaceuticals, Kyowa Pharma; Luitpold; Mardil; MedImmune; Medtronic Diabetes; Medicaltronic Vascular; Merck Group; MicroMed Technology; Mitsubishi Tanabe; Momenta; Nabriva?

Output: *No financial relationship.†Significant (greater than $10 000) relationship.‡

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: GlaxoSmithKline; Guidant Corp.; Heartscape Technologies; Ikaria; Imcor Pharmaceuticals; Inimex; Janssen; Johnson and Johnson; Juju Therapeutics; KAI Pharmaceuticals, Kyowa Pharma; Luitpold; Mardil; MedImmune; Medtronic Diabetes; Medicaltronic Vascular; Merck Group; MicroMed Technology; Mitsubishi Tanabe; Momenta; Nabriva?. ### Response: *No financial relationship.†Significant (greater than $10 000) relationship.‡.


Instruction: Merck Group; MicroMed Technology; Millennium Pharmaceuticals; Mitsubishi Tanabe; Nabriva; NitroMed; NovaCardia Inc; Novartis AG Group; Oncura; Ortho-McNeil-Janssen; OSI Eyetech; Pfizer; Pharmacyclics; Pharmasset; Pharmos; Phyxius Pharmaceuticals, Pharsight; Proventys; Regado Biosciences; Rengeneron Pharmaceuticals; Roche Group;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Merck Group; MicroMed Technology; Millennium Pharmaceuticals; Mitsubishi Tanabe; Nabriva; NitroMed; NovaCardia Inc; Novartis AG Group; Oncura; Ortho-McNeil-Janssen; OSI Eyetech; Pfizer; Pharmacyclics; Pharmasset; Pharmos; Phyxius Pharmaceuticals, Pharsight; Proventys; Regado Biosciences; Rengeneron Pharmaceuticals; Roche Group;. ### Response: †.


Instruction: Who is Regado Biosciences?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Regado Biosciences?. ### Response: †.


Instruction: What is Rengeneron Pharmaceuticals called?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Rengeneron Pharmaceuticals called?. ### Response: †.


Instruction: Who is Spectranetics a part of?

Output: Southwest Oncology Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Spectranetics a part of?. ### Response: Southwest Oncology Group.


Instruction: What is the name of the pharmaceutical company?

Output: The Medicines Company

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pharmaceutical company?. ### Response: The Medicines Company.


Instruction: What company is a part of the EMMES Corporation?

Output: Three Rivers Pharmaceuticals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What company is a part of the EMMES Corporation?. ### Response: Three Rivers Pharmaceuticals.


Instruction: Where is UCB?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is UCB?. ### Response: †.


Instruction: What is Chlorthalidone preferred on the basis of?

Output: prolonged half-life and proven trial reduction of CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chlorthalidone preferred on the basis of?. ### Response: prolonged half-life and proven trial reduction of CVD.


Instruction: What is monitored for hyponatremia and hypokalemia, uric acid and calcium levels?

Output: Oral Antihypertensive Drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is monitored for hyponatremia and hypokalemia, uric acid and calcium levels?. ### Response: Oral Antihypertensive Drugs.


Instruction: Hyponatremia and hypokalemia, uric acid and calcium levels?

Output: Monitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyponatremia and hypokalemia, uric acid and calcium levels?. ### Response: Monitor.


Instruction: Use with caution in patients with history of acute gout unless patient is on what?

Output: uric acid–lowering therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Use with caution in patients with history of acute gout unless patient is on what?. ### Response: uric acid–lowering therapy.


Instruction: Do not use in combination with ARBs or direct renin inhibitors?

Output: ACE inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do not use in combination with ARBs or direct renin inhibitors?. ### Response: ACE inhibitors.


Instruction: What is an increased risk of?

Output: hyperkalemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increased risk of?. ### Response: hyperkalemia.


Instruction: What type of stenosis does ACE inhibitors cause?

Output: bilateral renal artery stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stenosis does ACE inhibitors cause?. ### Response: bilateral renal artery stenosis.


Instruction: What is the recommended dose of Captopril?

Output: 12.5–150 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended dose of Captopril?. ### Response: 12.5–150 2.


Instruction: What is a risk of hyperkalemia in patients with CKD?

Output: increased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk of hyperkalemia in patients with CKD?. ### Response: increased.


Instruction: What is the risk of acute renal failure?

Output: There is a risk of acute renal failure in patients with severe bilateral renal artery stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of acute renal failure?. ### Response: There is a risk of acute renal failure in patients with severe bilateral renal artery stenosis.


Instruction: How many ARBs are Azilsartan 40 to 80?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ARBs are Azilsartan 40 to 80?. ### Response: 1.


Instruction: What is a risk of acute renal failure in patients with severe bilateral renal artery stenosis?

Output: There is a risk of acute renal failure in patients with severe bilateral renal artery stenosis.Do not use if patient has history of angioedema with ACE inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk of acute renal failure in patients with severe bilateral renal artery stenosis?. ### Response: There is a risk of acute renal failure in patients with severe bilateral renal artery stenosis.Do not use if patient has history of angioedema with ACE inhibitors.


Instruction: Do not use if patient has history of angioedema with what?

Output: ARBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do not use if patient has history of angioedema with what?. ### Response: ARBs.


Instruction: Patients with a history of ACE inhibitor can receive an ARB beginning 6 weeks after what is discontinued?

Output: ACE inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with a history of ACE inhibitor can receive an ARB beginning 6 weeks after what is discontinued?. ### Response: ACE inhibitor.


Instruction: How many weeks after ACE inhibitor is discontinued?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many weeks after ACE inhibitor is discontinued?. ### Response: 6.


Instruction: What is a CCB—dihydropyridinesAmlodipine 2.5-10?

Output: 80 1Valsartan 80–320 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a CCB—dihydropyridinesAmlodipine 2.5-10?. ### Response: 80 1Valsartan 80–320 1.


Instruction: What are beta blockers associated with?

Output: dose-related pedal edema

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are beta blockers associated with?. ### Response: dose-related pedal edema.


Instruction: What is more common in women than men?

Output: dose-related pedal edema

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more common in women than men?. ### Response: dose-related pedal edema.


Instruction: Why are beta blockers not used in patients with HFrEF?

Output: increased risk of bradycardia and heart block

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are beta blockers not used in patients with HFrEF?. ### Response: increased risk of bradycardia and heart block.


Instruction: There are drug interactions with diltiazem and what other drug?

Output: verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are drug interactions with diltiazem and what other drug?. ### Response: verapamil.


Instruction: What is the CYP3A4 major substrate and moderate inhibitor of?

Output: verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CYP3A4 major substrate and moderate inhibitor of?. ### Response: verapamil.


Instruction: What is the preferred diuretic in patients with symptomatic HF?

Output: Diuretics—loop Bumetanide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preferred diuretic in patients with symptomatic HF?. ### Response: Diuretics—loop Bumetanide.


Instruction: What are diuretics preferred over?

Output: thiazides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are diuretics preferred over?. ### Response: thiazides.


Instruction: What is a monotherapy agent and minimally effective antihypertensive agent?

Output: Diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a monotherapy agent and minimally effective antihypertensive agent?. ### Response: Diuretics.


Instruction: What can be combined with a thiazide?

Output: potassium-sparing diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be combined with a thiazide?. ### Response: potassium-sparing diuretic.


Instruction: How long does it take to relieve anginal chest pain?

Output: 5  minut es

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to relieve anginal chest pain?. ### Response: 5  minut es.


Instruction: What is atypical chest pain in men and women?

Output: unrelated to activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atypical chest pain in men and women?. ### Response: unrelated to activity.


Instruction: Non-anginal chest pain diff erently in men and w omen?

Output: Do not define typical and atypical f eatur es of anginal chest pain and non-anginal chest pain diff erently in men and w omen. [2010] 1.3.3.3 Do not define typical and atypical f eatur es of anginal chest pain and non-anginal chest pain diff erently in et hnic gr oups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Non-anginal chest pain diff erently in men and w omen?. ### Response: Do not define typical and atypical f eatur es of anginal chest pain and non-anginal chest pain diff erently in men and w omen. [2010] 1.3.3.3 Do not define typical and atypical f eatur es of anginal chest pain and non-anginal chest pain diff erently in et hnic gr oups.


Instruction: Do not define typical and atypical f eatur es of what?

Output: anginal chest pain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do not define typical and atypical f eatur es of what?. ### Response: anginal chest pain.


Instruction: What factors are taken into account when estimating people's lik elihood of angina?

Output: • age • whet her t he person is male • cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What factors are taken into account when estimating people's lik elihood of angina?. ### Response: • age • whet her t he person is male • cardiovascular risk.


Instruction: What is a risk factor for cardiovascular risk?

Output: age • whet her t he person is male • cardiovascular risk f actors including: － a hist ory of smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for cardiovascular risk?. ### Response: age • whet her t he person is male • cardiovascular risk f actors including: － a hist ory of smoking.


Instruction: What is a family hist ory of pr ematur e cor onar y artery disease?

Output: CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a family hist ory of pr ematur e cor onar y artery disease?. ### Response: CAD.


Instruction: What is another car diovascular disease called?

Output: cor onar y artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another car diovascular disease called?. ### Response: cor onar y artery disease.


Instruction: What is a possible cause of angina?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible cause of angina?. ### Response: age.


Instruction: What type of pain is considered to be non-anginal?

Output: chest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of pain is considered to be non-anginal?. ### Response: chest.


Instruction: What is non-anginal?

Output: chest pain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is non-anginal?. ### Response: chest pain.


Instruction: What is a diagnosis of stable angina unlik ely ar e when t he chest pain is?

Output: • continuous or v ery prolonged and/or • unrelated to activity and/or

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a diagnosis of stable angina unlik ely ar e when t he chest pain is?. ### Response: • continuous or v ery prolonged and/or • unrelated to activity and/or.


Instruction: What is the name of the book that describes the onset of chest pain of suspect ed car diac origin?

Output: CG95

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes the onset of chest pain of suspect ed car diac origin?. ### Response: CG95.


Instruction: When will all right s be reserved?

Output: 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will all right s be reserved?. ### Response: 2022.


Instruction: How many Circulations were there on March 15, 2016?

Output: 1142

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Circulations were there on March 15, 2016?. ### Response: 1142.


Instruction: What was the focus of the 2015 Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction?

Output: Author Relationships With Industry and Other Entities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the 2015 Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction?. ### Response: Author Relationships With Industry and Other Entities.


Instruction: Who is the Chair of Baylor College of Medicine?

Output: Glenn N. Levine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of Baylor College of Medicine?. ### Response: Glenn N. Levine.


Instruction: What is the Director of Cardiac Care Unit?

Output: Glenn N. Levine, ChairBaylor College of Medicine—Professor of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Director of Cardiac Care Unit?. ### Response: Glenn N. Levine, ChairBaylor College of Medicine—Professor of Medicine.


Instruction: Who is Vice Chair of University of Michigan?

Output: Eric R. Bates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Vice Chair of University of Michigan?. ### Response: Eric R. Bates.


Instruction: Who is the Vice Chair of Geisinger Medical Center?

Output: James C. Blankenship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Chair of Geisinger Medical Center?. ### Response: James C. Blankenship.


Instruction: What is the name of the medical center that is the Director of Cardiology and Cardiac Catheterization Laboratories?

Output: Geisinger Medical Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the medical center that is the Director of Cardiology and Cardiac Catheterization Laboratories?. ### Response: Geisinger Medical Center.


Instruction: What is the name of the professor of Medicine and Radiology at Penn State Milton S. Hershey Medical Center?

Output: Charles E.  Chambers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of Medicine and Radiology at Penn State Milton S. Hershey Medical Center?. ### Response: Charles E.  Chambers.


Instruction: Who is Professor of Medicine and Radiology?

Output: Steven R. Bailey University of Texas  Medical Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Professor of Medicine and Radiology?. ### Response: Steven R. Bailey University of Texas  Medical Center.


Instruction: Who is Chief, Division of Cardiothoracic Surgery at Emory Clinic, Inc?

Output: Professor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Chief, Division of Cardiothoracic Surgery at Emory Clinic, Inc?. ### Response: Professor.


Instruction: What is the name of the professor of medicine at Rowan University?

Output: Steven M.  HollenbergCooper

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at Rowan University?. ### Response: Steven M.  HollenbergCooper.


Instruction: Who is the Vice Chairman of the Department of Cardiovascular Medicine at Cleveland Clinic?

Output: Umesh N. Khot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Chairman of the Department of Cardiovascular Medicine at Cleveland Clinic?. ### Response: Umesh N. Khot.


Instruction: Who is the President of Texas Tech University Health Sciences Center El Paso?

Output: Richard A. Lange

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the President of Texas Tech University Health Sciences Center El Paso?. ### Response: Richard A. Lange.


Instruction: What is the name of the associate professor of medicine at Brigham & Women's Hospital?

Output: Laura Mauri

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the associate professor of medicine at Brigham & Women's Hospital?. ### Response: Laura Mauri.


Instruction: Who is a Director of Data Coordinating Analysis Center?

Output: Roxana Mehran Columbia University Medical Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Director of Data Coordinating Analysis Center?. ### Response: Roxana Mehran Columbia University Medical Center.


Instruction: Who is the Associate Professor of Medicine at Mehran Columbia University Medical Center?

Output: Roxana

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Associate Professor of Medicine at Mehran Columbia University Medical Center?. ### Response: Roxana.


Instruction: What is the Chief Medical Officer at First Coast Cardiovascular Institute?

Output: Issam D. Moussa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Chief Medical Officer at First Coast Cardiovascular Institute?. ### Response: Issam D. Moussa.


Instruction: What is the name of the Chief Medical Officer at the Coast Cardiovascular Institute?

Output: Issam D. Moussa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Chief Medical Officer at the Coast Cardiovascular Institute?. ### Response: Issam D. Moussa.


Instruction: When was this article downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: April 28, 2023.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 62 of 134 VIII?

Output: Research Priorities  During the development of the 2020 VA/DoD HTN CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 62 of 134 VIII?. ### Response: Research Priorities  During the development of the 2020 VA/DoD HTN CPG.


Instruction: What was shown to be superior to routine office blood pressure measurements?

Output: Out-of-office blood pressure measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was shown to be superior to routine office blood pressure measurements?. ### Response: Out-of-office blood pressure measurements.


Instruction: What did the group identify as areas for future research?

Output: areas requiring stronger evidence to support current recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the group identify as areas for future research?. ### Response: areas requiring stronger evidence to support current recommendations.


Instruction: Pressure measurements were shown to be superior to what in predicting cardiovascular events?

Output: out -of-office blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pressure measurements were shown to be superior to what in predicting cardiovascular events?. ### Response: out -of-office blood pressure.


Instruction: Future studies should focus on impact of blood pressure management based on out-of-office blood pressure measurements on what?

Output: clinically relevant outcomes in hypertensive individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Future studies should focus on impact of blood pressure management based on out-of-office blood pressure measurements on what?. ### Response: clinically relevant outcomes in hypertensive individuals.


Instruction: What can be improved with management of HTN in the general population?

Output: patient -related outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be improved with management of HTN in the general population?. ### Response: patient -related outcomes.


Instruction: What is being increasingly recognized as equivalent to out-of-office blood pressure?

Output: AOBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is being increasingly recognized as equivalent to out-of-office blood pressure?. ### Response: AOBP.


Instruction: What should be included in future studies to determine the clinical significance?

Output: variation in appropriate management for blood pressure variation by time of day and season

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be included in future studies to determine the clinical significance?. ### Response: variation in appropriate management for blood pressure variation by time of day and season.


Instruction: What are areas of research that include the development of protocols allowing for self-monitoring of blood pressure?

Output: areas requiring stronger evidence to support current recommendations as well as research exploring new areas to guide future CPGs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are areas of research that include the development of protocols allowing for self-monitoring of blood pressure?. ### Response: areas requiring stronger evidence to support current recommendations as well as research exploring new areas to guide future CPGs.


Instruction: What type of protocols are being developed for self management and self -adjustment of antihypertensive medications?

Output: protocols allowing for self- management and self -adjustment of antihypertensive medications by hypertensive individuals, based on home self -monitoring of blood pressure  and provider guidance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of protocols are being developed for self management and self -adjustment of antihypertensive medications?. ### Response: protocols allowing for self- management and self -adjustment of antihypertensive medications by hypertensive individuals, based on home self -monitoring of blood pressure  and provider guidance.


Instruction: What is based on home self monitoring of blood pressure and provider guidance?

Output: self- management and self -adjustment of antihypertensive medications by hypertensive individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is based on home self monitoring of blood pressure and provider guidance?. ### Response: self- management and self -adjustment of antihypertensive medications by hypertensive individuals.


Instruction: In addition to demographic characteristics and comorbidities, what other characteristics would benefit the specific populations?

Output: blood pressure control, adherence, cardiovascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to demographic characteristics and comorbidities, what other characteristics would benefit the specific populations?. ### Response: blood pressure control, adherence, cardiovascular outcomes.


Instruction: What populations would benefit the most from self-monitoring of blood pressure?

Output: demographic characteristics and comorbidities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What populations would benefit the most from self-monitoring of blood pressure?. ### Response: demographic characteristics and comorbidities.


Instruction: Blood pressure control, adherence, and cardiovascular outcomes may be improved with what?

Output: self -monitoring of blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood pressure control, adherence, and cardiovascular outcomes may be improved with what?. ### Response: self -monitoring of blood pressure.


Instruction: Future research on application of new technology in management of what type of populations?

Output: general population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Future research on application of new technology in management of what type of populations?. ### Response: general population.


Instruction: What technology should be used in future research on management of HTN?

Output: telemonitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What technology should be used in future research on management of HTN?. ### Response: telemonitoring.


Instruction: What should improve patients’ adherence to medications and enable communication with healthcare providers to maximize access to treatment?

Output: telemonitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should improve patients’ adherence to medications and enable communication with healthcare providers to maximize access to treatment?. ### Response: telemonitoring.


Instruction: What is needed to evaluate cost effectiveness and impact on patient -related clinical outcomes?

Output: high quality randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to evaluate cost effectiveness and impact on patient -related clinical outcomes?. ### Response: high quality randomized trials.


Instruction: What is required to combine prescription drug management, implementation of a healthy lifestyle and diet, and monitoring of adherence to interventions?

Output: HTN treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required to combine prescription drug management, implementation of a healthy lifestyle and diet, and monitoring of adherence to interventions?. ### Response: HTN treatment.


Instruction: What do nurse-led and pharmacist-led antihypertensive medication titration programs do?

Output: cost -effectiveness and impact on patient -related clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do nurse-led and pharmacist-led antihypertensive medication titration programs do?. ### Response: cost -effectiveness and impact on patient -related clinical outcomes.


Instruction: What do registered dietitian-led interventions target?

Output: healthy lifesty le changes and diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do registered dietitian-led interventions target?. ### Response: healthy lifesty le changes and diet.


Instruction: How does adherence monitoring improve blood pressure control?

Output: patient -centered outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does adherence monitoring improve blood pressure control?. ### Response: patient -centered outcomes.


Instruction: E. Diet and E xercise are two ways to improve what?

Output: patients’ adherence to medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: E. Diet and E xercise are two ways to improve what?. ### Response: patients’ adherence to medications.


Instruction: How long after onset of acute myocardial infarction was alteplase used?

Output: 6-24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after onset of acute myocardial infarction was alteplase used?. ### Response: 6-24 hours.


Instruction: What is EMERAS?

Output: Estudio Multicentrico Estreptoquinasa Republicas de America del Sur

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EMERAS?. ### Response: Estudio Multicentrico Estreptoquinasa Republicas de America del Sur.


Instruction: When was the trial of late throm-bolysis done?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the trial of late throm-bolysis done?. ### Response: 1993.


Instruction: What was added to conventional therapy in patients with ischemic cardiac pain at rest?

Output: tissue-type plasminogen activator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was added to conventional therapy in patients with ischemic cardiac pain at rest?. ### Response: tissue-type plasminogen activator.


Instruction: What was the name of the trial that showed early effects of tissue-type plasminogen activator?

Output: GUSTO IIb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the trial that showed early effects of tissue-type plasminogen activator?. ### Response: GUSTO IIb.


Instruction: What is the prognostic value of lead aVR in patients with a first non-ST-segment elevation acute myocardial infarction?

Output: 85

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic value of lead aVR in patients with a first non-ST-segment elevation acute myocardial infarction?. ### Response: 85.


Instruction: Circulation. 2003;108:814–19.

Output: 86

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2003;108:814–19.. ### Response: 86.


Instruction: What is a new ECG sign of?

Output: proxi-mal LAD occlusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new ECG sign of?. ### Response: proxi-mal LAD occlusion.


Instruction: N Engl J Med. 2008;359:2071–3.

Output: occlusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: N Engl J Med. 2008;359:2071–3.. ### Response: occlusion.


Instruction: What can be predicted with 12-lead electrocardiography in patients with acute myocardial infarction?

Output: left main coronary artery lesion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be predicted with 12-lead electrocardiography in patients with acute myocardial infarction?. ### Response: left main coronary artery lesion.


Instruction: What is the effect of thrombolytic therapy on left main coronary artery lesion?

Output: Reciprocal changes in 12-lead electrocardi-ography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of thrombolytic therapy on left main coronary artery lesion?. ### Response: Reciprocal changes in 12-lead electrocardi-ography.


Instruction: What was the effect of thrombolytic therapy on 12-month survival in the SHOCK trial?

Output: Influence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of thrombolytic therapy on 12-month survival in the SHOCK trial?. ### Response: Influence.


Instruction: What is a convenient, bedside, clini-cal score for risk of ST-elevation myocardial infarction?

Output: TIMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a convenient, bedside, clini-cal score for risk of ST-elevation myocardial infarction?. ### Response: TIMI.


Instruction: What is a convenient, bedside, clini-cal score for risk assessment at presentation?

Output: An intravenous nPA for treatment of infarcting myocardium early II trial substudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a convenient, bedside, clini-cal score for risk assessment at presentation?. ### Response: An intravenous nPA for treatment of infarcting myocardium early II trial substudy.


Instruction: What is an intravenous nPA for?

Output: treatment of infarcting myocardium early II trial substudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an intravenous nPA for?. ### Response: treatment of infarcting myocardium early II trial substudy.


Instruction: What is GUSTO IIb?

Output: A clinical trial comparing primary coronary angioplasty with tissue plas-minogen activator for acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GUSTO IIb?. ### Response: A clinical trial comparing primary coronary angioplasty with tissue plas-minogen activator for acute myocardial infarction.


Instruction: What is the clinical trial comparing primary coronary angioplasty with tissue plas-minogen activator for?

Output: acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical trial comparing primary coronary angioplasty with tissue plas-minogen activator for?. ### Response: acute myocardial infarction.


Instruction: What is the benefit of primary angioplasty compared with thrombolytic therapy for acute myocardial infarction?

Output: Long-term benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of primary angioplasty compared with thrombolytic therapy for acute myocardial infarction?. ### Response: Long-term benefit.


Instruction: What was the N Engl J Med. 1999;341:1413-19?

Output: Long-term benefit of primary angioplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med. 1999;341:1413-19?. ### Response: Long-term benefit of primary angioplasty.


Instruction: How many randomised trials were there in 2003?

Output: 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomised trials were there in 2003?. ### Response: 23.


Instruction: What is the name of the Danish multicenter randomized study on fibrinolytic therapy versus acute coronary angioplas-ty in acute myocardial infarction?

Output: DANish trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Danish multicenter randomized study on fibrinolytic therapy versus acute coronary angioplas-ty in acute myocardial infarction?. ### Response: DANish trial.


Instruction: What is a citywide protocol for in ST-segment elevation myocardial infarction?

Output: prima-ry PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a citywide protocol for in ST-segment elevation myocardial infarction?. ### Response: prima-ry PCI.


Instruction: What does transfer for primary angio-plasty versus immediate thrombolysis do?

Output: a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does transfer for primary angio-plasty versus immediate thrombolysis do?. ### Response: a meta-analysis.


Instruction: What is the citywide protocol for primary PCI in ST-segment elevation myocardial infarction?

Output: prima-ry PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the citywide protocol for primary PCI in ST-segment elevation myocardial infarction?. ### Response: prima-ry PCI.


Instruction: What did Schoenenberger AW, Moser A, Bertschi D, et al. combine with conventional risk scores to improve risk pre-diction after transcatheter aortic valve replacement?

Output: frailty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Schoenenberger AW, Moser A, Bertschi D, et al. combine with conventional risk scores to improve risk pre-diction after transcatheter aortic valve replacement?. ### Response: frailty.


Instruction: What did the FRAILTY-AVR study combine with?

Output: conventional risk scores

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the FRAILTY-AVR study combine with?. ### Response: conventional risk scores.


Instruction: What is the FRAILTY-AVR study?

Output: Frailty in older adults undergoing aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the FRAILTY-AVR study?. ### Response: Frailty in older adults undergoing aortic valve replacement.


Instruction: What was the J Am Coll Cardiol 2017:70:689–700?

Output: Frailty in older adults undergoing aortic valve replacement: the FRAILTY-AVR study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol 2017:70:689–700?. ### Response: Frailty in older adults undergoing aortic valve replacement: the FRAILTY-AVR study.


Instruction: What is the acronym for Placement of Aortic Transcatheter Valve?

Output: PARTNER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Placement of Aortic Transcatheter Valve?. ### Response: PARTNER.


Instruction: What are the results of the PARTNER trial?

Output: Predictors of poor outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the PARTNER trial?. ### Response: Predictors of poor outcomes.


Instruction: What is the name of the aortic transcatheter valve trial?

Output: PARTNER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the aortic transcatheter valve trial?. ### Response: PARTNER.


Instruction: What are the outcomes of patients with severe chronic lung disease who are undergoing surgery?

Output: Improved functional status and quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes of patients with severe chronic lung disease who are undergoing surgery?. ### Response: Improved functional status and quality of life.


Instruction: How many patients with severe chronic lung disease are undergoing transcatheter aortic valve re-placement?

Output: 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with severe chronic lung disease are undergoing transcatheter aortic valve re-placement?. ### Response: 14.


Instruction: What is the impact of preoperative chronic kidney disease in 2,531 high-risk and inoperable patients?

Output: transcatheter aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of preoperative chronic kidney disease in 2,531 high-risk and inoperable patients?. ### Response: transcatheter aortic valve replacement.


Instruction: What is the name of the PARTNER trial?

Output: Place-ment of Aortic Transcatheter Valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PARTNER trial?. ### Response: Place-ment of Aortic Transcatheter Valve.


Instruction: What is another name for transcatheter aortic valve replacement?

Output: STS/ACC TVT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for transcatheter aortic valve replacement?. ### Response: STS/ACC TVT.


Instruction: How many patients are likely to benefit from TAVI?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients are likely to benefit from TAVI?. ### Response: 12.


Instruction: What is the name of the study that evaluated mitral valve repair in high-risk patients?

Output: EVEREST II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated mitral valve repair in high-risk patients?. ### Response: EVEREST II.


Instruction: What are the results of the EVEREST II study?

Output: Percutaneous mitral valve repair for mitral regurgitation in high-risk patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the EVEREST II study?. ### Response: Percutaneous mitral valve repair for mitral regurgitation in high-risk patients.


Instruction: How many patients were enrolled in the 2014 J Am Coll Cardiol 64:172–81?

Output: 18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the 2014 J Am Coll Cardiol 64:172–81?. ### Response: 18.


Instruction: What is the status and quality of life in prohibitive surgical risk patients with degenerative mi-tral regurgitation after transcatheter mitral valve repair?

Output: Improved functional

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the status and quality of life in prohibitive surgical risk patients with degenerative mi-tral regurgitation after transcatheter mitral valve repair?. ### Response: Improved functional.


Instruction: What is Stone GW, Lindenfeld J, Abraham WT, et al.?

Output: Transcatheter mitral-valve repair in patients with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Stone GW, Lindenfeld J, Abraham WT, et al.?. ### Response: Transcatheter mitral-valve repair in patients with heart failure.


Instruction: What is the N Engl J Med. 2018:379:2307–18?

Output: ve repair in patients with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2018:379:2307–18?. ### Response: ve repair in patients with heart failure.


Instruction: What is a major factor in hospital volume and surgi-cal mortality in the United States?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major factor in hospital volume and surgi-cal mortality in the United States?. ### Response: heart failure.


Instruction: How many years ago did N Eng j Med. 2002:346:1128–37?

Output: 21

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years ago did N Eng j Med. 2002:346:1128–37?. ### Response: 21.