Instruction: What has been shown to reduce all-cause mortality and car-diovascular morbidity in multiple studies?

Output: Medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to reduce all-cause mortality and car-diovascular morbidity in multiple studies?. ### Response: Medical therapy.


Instruction: What should be prescribed to all patients who are eligible for them after PCI?

Output: medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be prescribed to all patients who are eligible for them after PCI?. ### Response: medications.


Instruction: What is the life expectancy of a patient?

Output: limited

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the life expectancy of a patient?. ### Response: limited.


Instruction: What is less than optimal for statin therapy?

Output: the use of these medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less than optimal for statin therapy?. ### Response: the use of these medications.


Instruction: Who evaluated the use of opti-mal medical therapy in patients undergoing PCI for stable dis-ease?

Output: Borden and colleagues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who evaluated the use of opti-mal medical therapy in patients undergoing PCI for stable dis-ease?. ### Response: Borden and colleagues.


Instruction: What percentage of patients who were discharged alive after PCI were prescribed statins?

Output: 83%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients who were discharged alive after PCI were prescribed statins?. ### Response: 83%.


Instruction: After PCI, who was discharged alive after PCI?

Output: Statins were prescribed to 83% of patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After PCI, who was discharged alive after PCI?. ### Response: Statins were prescribed to 83% of patients.


Instruction: Who was excluded after exclusion of patients with a contraindication to or history of intolerance of statins?

Output: Statins were prescribed to 83% of patients who were discharged alive after PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was excluded after exclusion of patients with a contraindication to or history of intolerance of statins?. ### Response: Statins were prescribed to 83% of patients who were discharged alive after PCI.


Instruction: How long after off-pump coro-nary artery bypass grafting are cognitive outcomes in elderly high-risk patients?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after off-pump coro-nary artery bypass grafting are cognitive outcomes in elderly high-risk patients?. ### Response: 1 year.


Instruction: What is the name of the randomized trial that evaluated cognitive outcomes?

Output: Neurological Outcome Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial that evaluated cognitive outcomes?. ### Response: Neurological Outcome Research Group.


Instruction: What is Kneebone AC?

Output: A com-parison of neuropsychologic deficits after extracardiac and intracardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Kneebone AC?. ### Response: A com-parison of neuropsychologic deficits after extracardiac and intracardiac surgery.


Instruction: What is Knight JL's specialty?

Output: neuropsychologic deficits after extracardiac and intracardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Knight JL's specialty?. ### Response: neuropsychologic deficits after extracardiac and intracardiac surgery.


Instruction: When was the J Cardiothorac Vasc Anesth published?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Cardiothorac Vasc Anesth published?. ### Response: 2001.


Instruction: How many people were injured during cardiopulmonary bypass?

Output: 373

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were injured during cardiopulmonary bypass?. ### Response: 373.


Instruction: What year did J Thorac Cardiovasc Surg.121:1150-1160?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Thorac Cardiovasc Surg.121:1150-1160?. ### Response: 2001.


Instruction: What is the doi: 10.1067/mtc.2001.114099?

Output: J Thorac Cardiovasc Surg. 2001;121:1150–1160. doi: 10.1067/mtc.2001.114099. 374

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1067/mtc.2001.114099?. ### Response: J Thorac Cardiovasc Surg. 2001;121:1150–1160. doi: 10.1067/mtc.2001.114099. 374.


Instruction: How did Raymond PD, Hinton-Bayre AD, Radel M, Ray MJ, Marsh NA define significant change in neuropsychological test performance following cardiac surgery?

Output: Assessment of statistical change criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Raymond PD, Hinton-Bayre AD, Radel M, Ray MJ, Marsh NA define significant change in neuropsychological test performance following cardiac surgery?. ### Response: Assessment of statistical change criteria.


Instruction: What is the name of the multifactorial problem that affects cognitive change after coronary artery bypass surgery?

Output: coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multifactorial problem that affects cognitive change after coronary artery bypass surgery?. ### Response: coronary artery disease.


Instruction: What does Selnes OA, Goldsborough MA, Borowicz LM Jr, Enger C, Quaskey SA, McKhann GM do?

Output: Defining cognitive change after CABG: decline versus normal variability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Selnes OA, Goldsborough MA, Borowicz LM Jr, Enger C, Quaskey SA, McKhann GM do?. ### Response: Defining cognitive change after CABG: decline versus normal variability.


Instruction: When was the Ann Thorac Surg. 67:1669–1676?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Thorac Surg. 67:1669–1676?. ### Response: 1999.


Instruction: What is the difference between decline and normal variability after CABG?

Output: multifactorial problem

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between decline and normal variability after CABG?. ### Response: multifactorial problem.


Instruction: What is a comparison between percutaneous intervention and normal controls?

Output: Stable cognition after coronary artery bypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison between percutaneous intervention and normal controls?. ### Response: Stable cognition after coronary artery bypass grafting.


Instruction: How does Stable cognition after coronary artery bypass grafting compare?

Output: comparisons with percutaneous intervention and normal controls

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Stable cognition after coronary artery bypass grafting compare?. ### Response: comparisons with percutaneous intervention and normal controls.


Instruction: How long after coronary bypass surgery is cognitive decline absent?

Output: one year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after coronary bypass surgery is cognitive decline absent?. ### Response: one year.


Instruction: What is the difference between healthy controls and nonsurgical patients?

Output: Absence of cognitive decline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between healthy controls and nonsurgical patients?. ### Response: Absence of cognitive decline.


Instruction: What is the name of the prospective study of coronary artery bypass graft patients and nonsurgi-cal controls?

Output: Cognitive changes with coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study of coronary artery bypass graft patients and nonsurgi-cal controls?. ### Response: Cognitive changes with coronary artery disease.


Instruction: What is the difference between patients and nonsurgi-cal controls?

Output: Absence of cognitive decline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between patients and nonsurgi-cal controls?. ### Response: Absence of cognitive decline.


Instruction: What is a longitudinal assessment of neurocognitive function after coronary-artery bypass surgery?

Output: comparison to nonsurgical and healthy controls

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a longitudinal assessment of neurocognitive function after coronary-artery bypass surgery?. ### Response: comparison to nonsurgical and healthy controls.


Instruction: How long after coronary artery bypass surgery does cognitive change?

Output: 5 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after coronary artery bypass surgery does cognitive change?. ### Response: 5 years.


Instruction: What is the name of the study that assessed neurocognitive function after a coronary bypass surgery?

Output: randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that assessed neurocognitive function after a coronary bypass surgery?. ### Response: randomized trial.


Instruction: What is the name of the procedure used to bypass arteries?

Output: coro-nary artery bypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used to bypass arteries?. ### Response: coro-nary artery bypass grafting.


Instruction: How long does it take for a person to become cognizant after a surgical procedure?

Output: 5 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a person to become cognizant after a surgical procedure?. ### Response: 5 years.


Instruction: What is one of the reasons for the lack of cognition?

Output: coronary bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the reasons for the lack of cognition?. ### Response: coronary bypass surgery.


Instruction: What should be given as soon as possible to minimize bleeding risk?

Output: A loading dose of 162 to 325 mg of non–enteric-coated aspirin formulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given as soon as possible to minimize bleeding risk?. ### Response: A loading dose of 162 to 325 mg of non–enteric-coated aspirin formulation.


Instruction: What is the name of the second international study of infarct survival?

Output: ISIS-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the second international study of infarct survival?. ### Response: ISIS-2.


Instruction: How much relative risk reduction did aspirin therapy reduce in 5-week vascular mortality?

Output: 23%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much relative risk reduction did aspirin therapy reduce in 5-week vascular mortality?. ### Response: 23%.


Instruction: How much absolute risk reduction was there in patients with STEMI?

Output: 2.4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much absolute risk reduction was there in patients with STEMI?. ### Response: 2.4%.


Instruction: What was the name of the second international study of infarct survival?

Output: ISIS-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the second international study of infarct survival?. ### Response: ISIS-2.


Instruction: Aspirin reduced the incidence of non-fatal reinfarction and stroke with what?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin reduced the incidence of non-fatal reinfarction and stroke with what?. ### Response: aspirin.


Instruction: What should be given before primary PCI?

Output: Aspirin 162 to 325 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given before primary PCI?. ### Response: Aspirin 162 to 325 mg.


Instruction: What should be given to patients with STEMI who receive fibrinolytic therapy?

Output: Aspirin (162- to 325-mg loading dose) and clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given to patients with STEMI who receive fibrinolytic therapy?. ### Response: Aspirin (162- to 325-mg loading dose) and clopidogrel.


Instruction: What is the Class I, Level of Evidence: B)2?

Output: Aspirin 162 to 325 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class I, Level of Evidence: B)2?. ### Response: Aspirin 162 to 325 mg.


Instruction: What should be given to all patients with NSTE-ACS without contraindications as soon as possible after receiving fibrinolytic therapy?

Output: Non–enteric-coated, chewable aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given to all patients with NSTE-ACS without contraindications as soon as possible after receiving fibrinolytic therapy?. ### Response: Non–enteric-coated, chewable aspirin.


Instruction: What is the Class I, Level of Evidence: A?

Output: I who receive fibrinolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class I, Level of Evidence: A?. ### Response: I who receive fibrinolytic therapy.


Instruction: What should patients with NSTE-ACS without contraindications be given as soon as possible after presentation?

Output: Non–enteric-coated, chewable aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with NSTE-ACS without contraindications be given as soon as possible after presentation?. ### Response: Non–enteric-coated, chewable aspirin.


Instruction: What should be continued indefinitely?

Output: a maintenance dose of aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be continued indefinitely?. ### Response: a maintenance dose of aspirin.


Instruction: How much aspirin should patients be given before PCI?

Output: 162 to 325 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much aspirin should patients be given before PCI?. ### Response: 162 to 325 mg.


Instruction: How much aspirin should be given to patients with NSTE-ACS before PCI?

Output: 162 to 325 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much aspirin should be given to patients with NSTE-ACS before PCI?. ### Response: 162 to 325 mg.


Instruction: What is the Class I level of evidence for NSTE ACS?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class I level of evidence for NSTE ACS?. ### Response: B.


Instruction: Why are patients unable to take aspirine because of hypersensitivity or major gastrointestinal intolerance?

Output: a loading dose of clopidogrel followed by a daily maintenance dose should be administered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are patients unable to take aspirine because of hypersensitivity or major gastrointestinal intolerance?. ### Response: a loading dose of clopidogrel followed by a daily maintenance dose should be administered.


Instruction: What does ACC stand for?

Output: American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACC stand for?. ### Response: American College of Cardiology.


Instruction: What is the acronym for the American College of Cardiology?

Output: ACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology?. ### Response: ACC.


Instruction: AMI stands for acute myocardial infarction.

Output: MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AMI stands for acute myocardial infarction.. ### Response: MI.


Instruction: ISIS-2 stands for what?

Output: Second International Study of Infarct Survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ISIS-2 stands for what?. ### Response: Second International Study of Infarct Survival.


Instruction: What is LBBB?

Output: left bundle branch block

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LBBB?. ### Response: left bundle branch block.


Instruction: What is MI?

Output: myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MI?. ### Response: myocardial infarction.


Instruction: Where can you download this article?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you download this article?. ### Response: http://.


Instruction: When was this article published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 28, 2023.


Instruction: What is the hazard ratio of cardiacarrest?

Output: 0.89

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the hazard ratio of cardiacarrest?. ### Response: 0.89.


Instruction: What are some secondary endpoints?

Output: nonfatal MIand coronary revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some secondary endpoints?. ### Response: nonfatal MIand coronary revascularization.


Instruction: How many drug regimens did the trials compare?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drug regimens did the trials compare?. ### Response: 2.


Instruction: How many drug regimens were com-pared?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drug regimens were com-pared?. ### Response: 2.


Instruction: What did not directly test the benefit of achieving a given level of LDL cholesterol?

Output: 2 drug regimens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not directly test the benefit of achieving a given level of LDL cholesterol?. ### Response: 2 drug regimens.


Instruction: There is no clear evidence that treating to a specific target is beneficial?

Output: LDL cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no clear evidence that treating to a specific target is beneficial?. ### Response: LDL cholesterol.


Instruction: What is a higher-potencystatin?

Output: higher dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a higher-potencystatin?. ### Response: higher dose.


Instruction: What are the mean achieved LDL cholesterol levels among patients treated in the TNT and IDEAL studies?

Output: 77 and 81 mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the mean achieved LDL cholesterol levels among patients treated in the TNT and IDEAL studies?. ### Response: 77 and 81 mg/dL.


Instruction: These data support intensive LDL loweringwith what?

Output: statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: These data support intensive LDL loweringwith what?. ### Response: statins.


Instruction: An update of the ATP-III report recommends treatment to what level?

Output: LDLcholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: An update of the ATP-III report recommends treatment to what level?. ### Response: LDLcholesterol.


Instruction: What does the ATP-III recommend in patients with establishedCAD or other high-risk features?

Output: treatment to an LDLcholesterol level /H11021100 mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ATP-III recommend in patients with establishedCAD or other high-risk features?. ### Response: treatment to an LDLcholesterol level /H11021100 mg/dL.


Instruction: What is the LDL cholesterolgoal of /H1102170 mg/dL?

Output: /H11021100 mg/dL in patients with establishedCAD or other high-risk features, with an LDL cholesterolgoal of /H1102170 mg/dL as a therapeutic option in patients atvery high risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LDL cholesterolgoal of /H1102170 mg/dL?. ### Response: /H11021100 mg/dL in patients with establishedCAD or other high-risk features, with an LDL cholesterolgoal of /H1102170 mg/dL as a therapeutic option in patients atvery high risk.


Instruction: What is the benefit of statin therapy for SIHD?

Output: LDL cholesterol lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of statin therapy for SIHD?. ### Response: LDL cholesterol lowering.


Instruction: What do the recommendations in this guideline stress?

Output: theimportance of prescribing a statin in at least a moderatedose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the recommendations in this guideline stress?. ### Response: theimportance of prescribing a statin in at least a moderatedose.


Instruction: When is the ATP-IV report expected?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the ATP-IV report expected?. ### Response: 2012.


Instruction: What is expected to provide guidance for the treatment of LDLcholesterol levels?

Output: The ATP-IV report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is expected to provide guidance for the treatment of LDLcholesterol levels?. ### Response: The ATP-IV report.


Instruction: What is one of the major risk factors identified in the ATP-III update?

Output: diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the major risk factors identified in the ATP-III update?. ### Response: diabetes mellitus.


Instruction: What is another risk factor that is identified as a very high risk?

Output: CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another risk factor that is identified as a very high risk?. ### Response: CAD.


Instruction: How many risk factors are there for diabetes mellitus?

Output: multiplemajor risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many risk factors are there for diabetes mellitus?. ### Response: multiplemajor risk factors.


Instruction: Is tobacco use a well controlled risk factor?

Output: poorly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is tobacco use a well controlled risk factor?. ### Response: poorly.


Instruction: No studies have evaluated the benefits of titrating lipid-lowering drugs to achieve what?

Output: a given level of LDL cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No studies have evaluated the benefits of titrating lipid-lowering drugs to achieve what?. ### Response: a given level of LDL cholesterol.


Instruction: What have trials of intensive lipid lowering forsecondary prevention used?

Output: statins alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have trials of intensive lipid lowering forsecondary prevention used?. ### Response: statins alone.


Instruction: What could lower LDL cholesterol inpatients in whom a target level cannot be achieved with astatin?

Output: the addition of other agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could lower LDL cholesterol inpatients in whom a target level cannot be achieved with astatin?. ### Response: the addition of other agents.


Instruction: What is a secondary target of therapy introduced by ATP-III?

Output: on–HDL cholesterol in patients with elevated triglycer-ides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a secondary target of therapy introduced by ATP-III?. ### Response: on–HDL cholesterol in patients with elevated triglycer-ides.


Instruction: Isnon-HDL cholesterol in patients with elevated triglycerides?

Output: isnon–HDL cholesterol in patients with elevated triglycer-ides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Isnon-HDL cholesterol in patients with elevated triglycerides?. ### Response: isnon–HDL cholesterol in patients with elevated triglycer-ides.


Instruction: What is Non-HDl cholesterol defined as the difference between total cholesterol and HDL cholesterol?

Output: It includes allcholesterol and lipoprotein particles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Non-HDl cholesterol defined as the difference between total cholesterol and HDL cholesterol?. ### Response: It includes allcholesterol and lipoprotein particles.


Instruction: What is ACEi versus placebo or standard care?

Output: no treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACEi versus placebo or standard care?. ### Response: no treatment.


Instruction: What is calcium channel blocker versus?

Output: placebo or no treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is calcium channel blocker versus?. ### Response: placebo or no treatment.


Instruction: ARB versus placebo or standard careTable S23.

Output: Adults with diabetes and CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ARB versus placebo or standard careTable S23.. ### Response: Adults with diabetes and CKD.


Instruction: Adults with diabetes and CKD, what versus ACEiTable S24?

Output: ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults with diabetes and CKD, what versus ACEiTable S24?. ### Response: ARB.


Instruction: What is a beta-blocker versus?

Output: ACEi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a beta-blocker versus?. ### Response: ACEi.


Instruction: What is the difference between beta-blocker and ACEi?

Output: placebo or no treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between beta-blocker and ACEi?. ### Response: placebo or no treatment.


Instruction: Adults with diabetes and CKD, calcium channel blocker versus what?

Output: placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults with diabetes and CKD, calcium channel blocker versus what?. ### Response: placebo.


Instruction: What are the differences between diuretics DACEi and ARB?

Output: no treatment, or standard of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between diuretics DACEi and ARB?. ### Response: no treatment, or standard of care.


Instruction: CKD, aliskiren versus ACEi or ARB.

Output: dual RASi therapy versus single RASi therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CKD, aliskiren versus ACEi or ARB.. ### Response: dual RASi therapy versus single RASi therapy.


Instruction: Adults with type 2 diabetes versus placebo DACEi and ARBTable S30 What is another name for calcium channel blocker?

Output: aliskiren

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults with type 2 diabetes versus placebo DACEi and ARBTable S30 What is another name for calcium channel blocker?. ### Response: aliskiren.


Instruction: What is the other name for single RASi therapy?

Output: ACEi or ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the other name for single RASi therapy?. ### Response: ACEi or ARB.


Instruction: What is the difference between dual and single RASi therapy?

Output: Adults with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between dual and single RASi therapy?. ### Response: Adults with CKD.


Instruction: What are kidney transplant recipients given versus placebo or no treatment?

Output: calcium channel blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are kidney transplant recipients given versus placebo or no treatment?. ### Response: calcium channel blockers.


Instruction: What is ACEi versus placebo?

Output: ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACEi versus placebo?. ### Response: ARB.


Instruction: What is beta-blocker versus a placebo or no treatment?

Output: Kidney transplant recipients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beta-blocker versus a placebo or no treatment?. ### Response: Kidney transplant recipients.


Instruction: How are kidney transplant recipients treated?

Output: beta-blocker versus placebo or no treatmentTable S38. Kidney transplant recipients, mineralocorticoid receptor antagonists versus placeboTable S39. Kidney transplant recipients, ACEi or ARB versus placebo, no treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are kidney transplant recipients treated?. ### Response: beta-blocker versus placebo or no treatmentTable S38. Kidney transplant recipients, mineralocorticoid receptor antagonists versus placeboTable S39. Kidney transplant recipients, ACEi or ARB versus placebo, no treatment.


Instruction: What is the difference between ACEi and ARB?

Output: placebo, no treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between ACEi and ARB?. ### Response: placebo, no treatment.


Instruction: What are the differences between intensi fied blood pressure control and conventionalblood pressure control?

Output: MAP <50th percentile

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between intensi fied blood pressure control and conventionalblood pressure control?. ### Response: MAP <50th percentile.


Instruction: What was developed as part of the evidence review?

Output: Additional SoF tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed as part of the evidence review?. ### Response: Additional SoF tables.


Instruction: Correlation of blood pressure measurement techniques in patients with CKDTable S42.

Output: Accuracy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Correlation of blood pressure measurement techniques in patients with CKDTable S42.. ### Response: Accuracy.


Instruction: Accuracy of what in the general population?

Output: blood pressure measurement techniques

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Accuracy of what in the general population?. ### Response: blood pressure measurement techniques.


Instruction: Systematic reviews of approaches to what?

Output: blood pressure measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Systematic reviews of approaches to what?. ### Response: blood pressure measurement.


Instruction: What is the name of the systematic reviews of economic evaluations of differing approaches to BP measurement in the general population?

Output: Table S45

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic reviews of economic evaluations of differing approaches to BP measurement in the general population?. ### Response: Table S45.


Instruction: Adults with diabetes and CKD and habitual low-salt intake, higher dietary salt intake, versus regular-salted intake?

Output: NaClsupplement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults with diabetes and CKD and habitual low-salt intake, higher dietary salt intake, versus regular-salted intake?. ### Response: NaClsupplement.


Instruction: What is the difference between dietary salt intake and regular salt intake?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between dietary salt intake and regular salt intake?. ### Response: higher.


Instruction: Adults with diabetes and habitual high-salt intake have higher dietary sodium intake through what?

Output: NaClsupplement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults with diabetes and habitual high-salt intake have higher dietary sodium intake through what?. ### Response: NaClsupplement.


Instruction: What is ences in stroke risk?

Output: Sex differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ences in stroke risk?. ### Response: Sex differences.


Instruction: What is the REGARDS Study?

Output: Sex differences in stroke incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the REGARDS Study?. ### Response: Sex differences in stroke incidence.


Instruction: What is the name of the Atherosclerosis Risk in Communities cohort?

Output: ARIC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Atherosclerosis Risk in Communities cohort?. ### Response: ARIC.


Instruction: When did the ARIC cohort follow-up?

Output: 9-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the ARIC cohort follow-up?. ### Response: 9-year.


Instruction: How long did it take for middle-aged adults to survive a stroke?

Output: 9-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for middle-aged adults to survive a stroke?. ### Response: 9-year.


Instruction: What was the Northern Manhattan Stroke Study?

Output: Stroke in the young

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Northern Manhattan Stroke Study?. ### Response: Stroke in the young.


Instruction: What is the name of the study that examined the incidence of stroke among white, black, and Hispanic residents of an urban community?

Output: Northern Manhattan Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the incidence of stroke among white, black, and Hispanic residents of an urban community?. ### Response: Northern Manhattan Stroke Study.


Instruction: What year did Reed SD, Curtis LH, Alexander MJ, Villani JJ, Schulman KA study nontraumatic subarachnoid hemorrhage in the United States?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Reed SD, Curtis LH, Alexander MJ, Villani JJ, Schulman KA study nontraumatic subarachnoid hemorrhage in the United States?. ### Response: 2003.


Instruction: What is the name of the journal that studies the characteristics of nontraumatic traumatic arachnoema in 2003?

Output: Neurosurgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the characteristics of nontraumatic traumatic arachnoema in 2003?. ### Response: Neurosurgery.


Instruction: In what year did Neurosurgery issue 61:1131-1137?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Neurosurgery issue 61:1131-1137?. ### Response: 2007.


Instruction: How many strokes were there in 1989?

Output: 20:718–724

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 1989?. ### Response: 20:718–724.


Instruction: What is the name of the disease that causes death?

Output: subarachnoid hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes death?. ### Response: subarachnoid hemorrhage.


Instruction: How long does it take for a person to survive a subarachnoid hemorrhage?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a person to survive a subarachnoid hemorrhage?. ### Response: 10-year.


Instruction: Where is the Akita Prefecture located?

Output: Japan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Akita Prefecture located?. ### Response: Japan.


Instruction: What year was the J Neurosurg 106?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the J Neurosurg 106?. ### Response: 2007.


Instruction: What is the survival rate of subarachnoid hemorrhage in a population-based registry?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the survival rate of subarachnoid hemorrhage in a population-based registry?. ### Response: 10-year.


Instruction: When did van Munster CE, von und zu Fraunberg M, Rinkel GJ, Rinne J, Koivisto T, Ronkainen A. develop differences in aneurysm and patient characteristics between Finnish and Dutch patients?

Output: between 1986 and 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did van Munster CE, von und zu Fraunberg M, Rinkel GJ, Rinne J, Koivisto T, Ronkainen A. develop differences in aneurysm and patient characteristics between Finnish and Dutch patients?. ### Response: between 1986 and 2005.


Instruction: What year did subarachnoid hemorrhage occur in Sweden?

Output: 1987–2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did subarachnoid hemorrhage occur in Sweden?. ### Response: 1987–2002.


Instruction: What is the name of the disease that occurred in Sweden between 1987 and 2002?

Output: Subarachnoid haemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that occurred in Sweden between 1987 and 2002?. ### Response: Subarachnoid haemorrhage.


Instruction: What year did the Canadian Collaborative Study Group of Stroke Hospitalizations conduct a study?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Canadian Collaborative Study Group of Stroke Hospitalizations conduct a study?. ### Response: 1991.


Instruction: What is the name of the study that examined hospitalization and case-fatality rates for subarachnoid hemorrhage in Canada from 1982 to 1991?

Output: Canadian Collaborative Study Group of Stroke Hospitalizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined hospitalization and case-fatality rates for subarachnoid hemorrhage in Canada from 1982 to 1991?. ### Response: Canadian Collaborative Study Group of Stroke Hospitalizations.


Instruction: What is the incidence of cerebrovascular disease in southern Sweden?

Output: Sex differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence of cerebrovascular disease in southern Sweden?. ### Response: Sex differences.


Instruction: What are the sex differences in incidence of?

Output: cerebrovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the sex differences in incidence of?. ### Response: cerebrovascular disease.


Instruction: When was the J Epidemiol Community Health published?

Output: 1981

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Epidemiol Community Health published?. ### Response: 1981.


Instruction: What is the name of the study that studied young people's strokes?

Output: Northern Manhattan Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that studied young people's strokes?. ### Response: Northern Manhattan Stroke Study.


Instruction: When was the Northern Manhattan Stroke Study published?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Northern Manhattan Stroke Study published?. ### Response: 1998.


Instruction: What was the name given to the study?

Output: Northern Manhattan Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name given to the study?. ### Response: Northern Manhattan Stroke Study.


Instruction: What is the name of the population-based study of event-rate, incidence, case fatality, and mortality for all acute vasculitis?

Output: the REGARDS Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the population-based study of event-rate, incidence, case fatality, and mortality for all acute vasculitis?. ### Response: the REGARDS Study.


Instruction: What does FC, Binney LE, Gutnikov SA, Anslow P, Banning AP, Mant D, and Mehta Z do?

Output: Cuthbertson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does FC, Binney LE, Gutnikov SA, Anslow P, Banning AP, Mant D, and Mehta Z do?. ### Response: Cuthbertson.


Instruction: What is the name of the systematic review of economic evaluations in kidney transplantation?

Output: Transplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of economic evaluations in kidney transplantation?. ### Response: Transplantation.


Instruction: How long does ambulatory blood pressure last in children?

Output: 24-h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does ambulatory blood pressure last in children?. ### Response: 24-h.


Instruction: When was J Hypertens 21:1995 –2007?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was J Hypertens 21:1995 –2007?. ### Response: 2002.


Instruction: What is the European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents?. ### Response: 2016.


Instruction: What are the values and role of bodydimensions?

Output: normalized reference values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the values and role of bodydimensions?. ### Response: normalized reference values.


Instruction: What is a role of antihypertensive drug management in childhood chronic renal parenchymal disease?

Output: Systemic hypertensionand proteinuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a role of antihypertensive drug management in childhood chronic renal parenchymal disease?. ### Response: Systemic hypertensionand proteinuria.


Instruction: What is the name of the randomized study that examined cardiac geometry andfunction in CKD children?

Output: Matteucci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized study that examined cardiac geometry andfunction in CKD children?. ### Response: Matteucci.


Instruction: What is the name of the randomized study conducted on children during strict BP control?

Output: Matteucci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized study conducted on children during strict BP control?. ### Response: Matteucci.


Instruction: What is a scientific statement from the American Heart Association?

Output: ambulatory bloodpressure monitoring in children and adolescents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scientific statement from the American Heart Association?. ### Response: ambulatory bloodpressure monitoring in children and adolescents.


Instruction: What is the difference between ambulatory and clinic blood pressure measurements in children with CKD?

Output: Twenty-four-hour

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between ambulatory and clinic blood pressure measurements in children with CKD?. ### Response: Twenty-four-hour.


Instruction: What is the difference between fice,ambulatory and home blood pressure in children and adolescents on the basis of normalcy tables?

Output: Comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between fice,ambulatory and home blood pressure in children and adolescents on the basis of normalcy tables?. ### Response: Comparison.


Instruction: When did the J Hum Hypertens. 2011:25:218–223.362?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Hum Hypertens. 2011:25:218–223.362?. ### Response: 2011.


Instruction: What was the name of the study that examined the accuracy of automated blood pressure measurements in children?

Output: Hypertension . 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that examined the accuracy of automated blood pressure measurements in children?. ### Response: Hypertension . 2017.


Instruction: What type of blood pressure monitoring is recommended in children with chronic renal failure?

Output: ambulatory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of blood pressure monitoring is recommended in children with chronic renal failure?. ### Response: ambulatory.


Instruction: What is the name of the journal that studies the prevalence of glomerular and nonglomerular kidney disease in children?

Output: Am J Kidney Dis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the prevalence of glomerular and nonglomerular kidney disease in children?. ### Response: Am J Kidney Dis.


Instruction: What is the Chronic Kidney Disease in Children cohort?

Output: CKiD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Chronic Kidney Disease in Children cohort?. ### Response: CKiD.


Instruction: What was the name of the systematic review of evidence on clinical utility?

Output: Home blood pressuremonitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic review of evidence on clinical utility?. ### Response: Home blood pressuremonitoring.


Instruction: What is the name of the systematic review of evidence on clinical utility?

Output: Home blood pressuremonitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of evidence on clinical utility?. ### Response: Home blood pressuremonitoring.


Instruction: What are the names of the authors?

Output: Stergiou GS, Karpettas N, Panagiotakos DB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors?. ### Response: Stergiou GS, Karpettas N, Panagiotakos DB.


Instruction: Who is the author of the abstract?

Output: Dionne JM, Jiang S, Ng D, et al. Ambulatory blood pressure and CKDprogression in the CKiD cohort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the abstract?. ### Response: Dionne JM, Jiang S, Ng D, et al. Ambulatory blood pressure and CKDprogression in the CKiD cohort.


Instruction: What is the name of the study that identified important outcomes for young people with CKD and their caregivers?

Output: a nominal group techniquestudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that identified important outcomes for young people with CKD and their caregivers?. ### Response: a nominal group techniquestudy.


Instruction: What is Halbach S. Practical application of ABPM in pediatric nephrologyclinic?

Output: Achieved clinic blood pressure level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Halbach S. Practical application of ABPM in pediatric nephrologyclinic?. ### Response: Achieved clinic blood pressure level.


Instruction: What was the blood pressure level in the clinic?

Output: Achieved clinic blood pressure level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the blood pressure level in the clinic?. ### Response: Achieved clinic blood pressure level.


Instruction: What is the glycemic index?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the glycemic index?. ### Response: blood pressure.


Instruction: How many people were able to achieve the clinic blood pressure?

Output: Flynn

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were able to achieve the clinic blood pressure?. ### Response: Flynn.


Instruction: What are some of the benefits of ACE inhibitors, ARBs, and -blockers?

Output: improve outcomes for patients with HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the benefits of ACE inhibitors, ARBs, and -blockers?. ### Response: improve outcomes for patients with HF.


Instruction: What is a significant proportion of patients with hypertension and BP treated with?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a significant proportion of patients with hypertension and BP treated with?. ### Response: HF.


Instruction: What percentage of patients in these trials had a history of hypertension?

Output: 40%–60%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in these trials had a history of hypertension?. ### Response: 40%–60%).


Instruction: The beneficial effects could be generalized to what population?

Output: hypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The beneficial effects could be generalized to what population?. ### Response: hypertensive.


Instruction: What have not been compelling data on?

Output: to justify a single BP target

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have not been compelling data on?. ### Response: to justify a single BP target.


Instruction: What has not been compelling to justify a single BP target in treating hypertension in patients with es-tablished HF?

Output: data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been compelling to justify a single BP target in treating hypertension in patients with es-tablished HF?. ### Response: data.


Instruction: Former guidelines and position papers differ significantly in what?

Output: such threshold definitions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Former guidelines and position papers differ significantly in what?. ### Response: such threshold definitions.


Instruction: What is the optimal BP target for the treat-ment of hypertension in patients with HF?

Output: not firmly established

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the optimal BP target for the treat-ment of hypertension in patients with HF?. ### Response: not firmly established.


Instruction: The 2007 AHA scientific statement recommended a target BP of 130/80 mmHg?

Output: 10.1161/CIR.0000000000000450 December 6, 2016 e539CLINICAL STATEMENTS  AND GUIDELINESremodeling, and improve LV function.57,58 Although these beneficial effects of ACE inhibitors, ARBs, and β-blockers are not specific for patients with hypertension or for treatment of BP, a significant proportion of patients in these trials (40%–60%) had a history of hypertension, and the beneficial effects could be generalized to the hypertensive population.Treatment of Hypertension in Patients With Established HF How Aggressively to Treat BP in Patients With HF?There have not been compelling data to justify a single BP target in treating hypertension in patients with es-tablished HF. Former guidelines and position papers differ significantly in such threshold definitions and lack strong evidence for treatment targets of hypertension in HF.9,14,48,59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The 2007 AHA scientific statement recommended a target BP of 130/80 mmHg?. ### Response: 10.1161/CIR.0000000000000450 December 6, 2016 e539CLINICAL STATEMENTS  AND GUIDELINESremodeling, and improve LV function.57,58 Although these beneficial effects of ACE inhibitors, ARBs, and β-blockers are not specific for patients with hypertension or for treatment of BP, a significant proportion of patients in these trials (40%–60%) had a history of hypertension, and the beneficial effects could be generalized to the hypertensive population.Treatment of Hypertension in Patients With Established HF How Aggressively to Treat BP in Patients With HF?There have not been compelling data to justify a single BP target in treating hypertension in patients with es-tablished HF. Former guidelines and position papers differ significantly in such threshold definitions and lack strong evidence for treatment targets of hypertension in HF.9,14,48,59.


Instruction: What did ischemic heart disease recommend for patients with HF?

Output: <130/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did ischemic heart disease recommend for patients with HF?. ### Response: <130/80 mm Hg.


Instruction: What did the 2002 AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke identify as the BP treatment goal?

Output: <130/85 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2002 AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke identify as the BP treatment goal?. ### Response: <130/85 mm Hg.


Instruction: What was the BP threshold in patients 60 years of age?

Output: 63–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the BP threshold in patients 60 years of age?. ### Response: 63–.


Instruction: What was BP lowering too aggressive?

Output: potential adverse outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was BP lowering too aggressive?. ### Response: potential adverse outcomes.


Instruction: What was the 2014 evidence-based guideline for the management of high BP in adults?

Output: 60 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2014 evidence-based guideline for the management of high BP in adults?. ### Response: 60 years of age.


Instruction: What did the writing committee not address in patients with es-tablished?

Output: BP treatment targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing committee not address in patients with es-tablished?. ### Response: BP treatment targets.


Instruction: What did not address BP treatment targets in patients with es-tablished HF?

Output: the writing committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not address BP treatment targets in patients with es-tablished HF?. ### Response: the writing committee.


Instruction: What is the lack of definitive BP targets for patients with existing HF notwithstanding?

Output: treatment of HF is usu-Table 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the lack of definitive BP targets for patients with existing HF notwithstanding?. ### Response: treatment of HF is usu-Table 4.


Instruction: What should patients with previous or current symptoms of HFrEF be treated with?

Output: GDMT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with previous or current symptoms of HFrEF be treated with?. ### Response: GDMT.


Instruction: What is GDMT used for?

Output: Patients with previous or current symptoms of HFrEF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GDMT used for?. ### Response: Patients with previous or current symptoms of HFrEF.


Instruction: What have been proven to improve outcomes for patients with HF?

Output: aldosterone receptor antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have been proven to improve outcomes for patients with HF?. ### Response: aldosterone receptor antagonists.


Instruction: What can lower BP in hypertensive patients?

Output: aldosterone receptor antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can lower BP in hypertensive patients?. ### Response: aldosterone receptor antagonists.


Instruction: ARB or ACE inhibitor can be added to the background treatment with what?

Output: hydralazine/isosorbide dinitrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ARB or ACE inhibitor can be added to the background treatment with what?. ### Response: hydralazine/isosorbide dinitrate.


Instruction: What is beneficial to reduce morbidity and mortality in self-described black patients with HFrEF and persistent NYHA class III or IVHF symptoms?

Output: Addition of hydralazine/isosorbide dinitrate to the background treatment with ACE inhibitor or ARB and β-blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial to reduce morbidity and mortality in self-described black patients with HFrEF and persistent NYHA class III or IVHF symptoms?. ### Response: Addition of hydralazine/isosorbide dinitrate to the background treatment with ACE inhibitor or ARB and β-blocker.


Instruction: What was the risk of Arterial Thrombosis in Relation to Oral Contraceptives (RATIO) study from the Netherlands?

Output: women who were obese (OR, 4.6; 95% CI, 2.4–8.9) and had a history of hypercholesterolemia (OR, 10.8; 95% CI, 2.3–49.9) were also at an increased risk from OC use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of Arterial Thrombosis in Relation to Oral Contraceptives (RATIO) study from the Netherlands?. ### Response: women who were obese (OR, 4.6; 95% CI, 2.4–8.9) and had a history of hypercholesterolemia (OR, 10.8; 95% CI, 2.3–49.9) were also at an increased risk from OC use.


Instruction: What were women who were obese at an increased risk from OC use?

Output: hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were women who were obese at an increased risk from OC use?. ### Response: hypercholesterolemia.


Instruction: What did RATIO investigators perform to identify prothrombotic mutations in women with stroke who were and were not OC users?

Output: multiple anal-yses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did RATIO investigators perform to identify prothrombotic mutations in women with stroke who were and were not OC users?. ### Response: multiple anal-yses.


Instruction: What was the risk of IS for women using OCs who were heterozygous for factor V Leiden?

Output: increased risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of IS for women using OCs who were heterozygous for factor V Leiden?. ### Response: increased risk.


Instruction: What mutation was at increased risk for methyl tetrahydrofolate reductase or MTHFR 677TT?

Output: factor V Leiden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What mutation was at increased risk for methyl tetrahydrofolate reductase or MTHFR 677TT?. ### Response: factor V Leiden.


Instruction: What may have been a synergism between OCs and these mutations?

Output: oral contraceptive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have been a synergism between OCs and these mutations?. ### Response: oral contraceptive.


Instruction: What was not evident in nonusers with these mutation?

Output: the increased risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not evident in nonusers with these mutation?. ### Response: the increased risk.


Instruction: The study showed an association with what genetic variation?

Output: fac-tor XIII

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The study showed an association with what genetic variation?. ### Response: fac-tor XIII.


Instruction: What was associated with 2.3-fold increased odds of stroke?

Output: β 2  glycoprotein-1 antibodies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with 2.3-fold increased odds of stroke?. ### Response: β 2  glycoprotein-1 antibodies.


Instruction: What was not associated with anticardiolipin or antiprothrombin antibodies?

Output: the presence of β 2  glycoprotein-1 antibodies was associated with 2.3-fold increased odds of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not associated with anticardiolipin or antiprothrombin antibodies?. ### Response: the presence of β 2  glycoprotein-1 antibodies was associated with 2.3-fold increased odds of stroke.


Instruction: The prevalence of what was 17% in women with IS?

Output: lupus anti-coagulant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The prevalence of what was 17% in women with IS?. ### Response: lupus anti-coagulant.


Instruction: What percentage of women with IS had an OR of 43.1 (95% CI, 12.2–152.0)?

Output: very high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of women with IS had an OR of 43.1 (95% CI, 12.2–152.0)?. ### Response: very high.


Instruction: What was the OR of 201 in women who were also using OCs?

Output: 22.1–1828.0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the OR of 201 in women who were also using OCs?. ### Response: 22.1–1828.0.


Instruction: What is another example of the amplification of IS risk in a condition that is already associated with arterial thromboembolism and VTE?

Output: OR increased to 201 (95% CI, 22.1–1828.0) in women who were also using OCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another example of the amplification of IS risk in a condition that is already associated with arterial thromboembolism and VTE?. ### Response: OR increased to 201 (95% CI, 22.1–1828.0) in women who were also using OCs.


Instruction: How were von Willebrand factor levels associated with increased odds of IS and MI in young women in the RATIO cohort?

Output: an increase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were von Willebrand factor levels associated with increased odds of IS and MI in young women in the RATIO cohort?. ### Response: an increase.


Instruction: How were the odds of Ischemic Stroke associated with the presence of Genetic or Acquired Prothrombotic Factors With and Without OC Use?

Output: Table 8. Odds of Ischemic Stroke With the Presence of Genetic or Acquired Prothrombotic Factors With and Without OC Use in the RATIO CohortAdjusted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the odds of Ischemic Stroke associated with the presence of Genetic or Acquired Prothrombotic Factors With and Without OC Use?. ### Response: Table 8. Odds of Ischemic Stroke With the Presence of Genetic or Acquired Prothrombotic Factors With and Without OC Use in the RATIO CohortAdjusted.


Instruction: What is the CI for Acquired Prothrombotic Factors With and Without OC Use in the RATIO Cohort?

Output: 95%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CI for Acquired Prothrombotic Factors With and Without OC Use in the RATIO Cohort?. ### Response: 95%.


Instruction: What indicates a disintegrin and metalloproteinase with the thrombospondin type I repeat 13?

Output: ADAMTS13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates a disintegrin and metalloproteinase with the thrombospondin type I repeat 13?. ### Response: ADAMTS13.


Instruction: What is FXIII?

Output: factor XIII

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is FXIII?. ### Response: factor XIII.


Instruction: What is MTHFR?

Output: methylenetetrahydrofolate reductase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MTHFR?. ### Response: methylenetetrahydrofolate reductase.


Instruction: WHAT is RATIO?

Output: Risk of Arterial Thrombosis in Relation to Oral Contraceptives

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: WHAT is RATIO?. ### Response: Risk of Arterial Thrombosis in Relation to Oral Contraceptives.


Instruction: What city is Emmanuel Letavernier located in?

Output: Paris

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What city is Emmanuel Letavernier located in?. ### Response: Paris.


Instruction: Where is Kaid Massy located?

Output: Paris

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Kaid Massy located?. ### Response: Paris.


Instruction: Who is located in Palo Alto?

Output: Timothy W. Meyer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is located in Palo Alto?. ### Response: Timothy W. Meyer.


Instruction: What city is Mark Okusa located in?

Output: Charlottesville

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What city is Mark Okusa located in?. ### Response: Charlottesville.


Instruction: What is the name of the city where Mark Perazella is located?

Output: New Haven

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the city where Mark Perazella is located?. ### Response: New Haven.


Instruction: Where is the city of New Haven?

Output: New York

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the city of New Haven?. ### Response: New York.


Instruction: What is the name of the New Haven resident?

Output: Robert Sa ﬁrstein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the New Haven resident?. ### Response: Robert Sa ﬁrstein.


Instruction: What city is home to San AntonioHeather Reich?

Output: Toronto

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What city is home to San AntonioHeather Reich?. ### Response: Toronto.


Instruction: Where is San Antonio located?

Output: San Francisco

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is San Antonio located?. ### Response: San Francisco.


Instruction: Who is the BostonKai Schmidt-Ott?

Output: New York

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the BostonKai Schmidt-Ott?. ### Response: New York.


Instruction: Where is the New YorkStephan Segerer?

Output: AarauK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the New YorkStephan Segerer?. ### Response: AarauK.


Instruction: What is the PhiladelphiaKatalin Susztak?

Output: Oxford

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PhiladelphiaKatalin Susztak?. ### Response: Oxford.


Instruction: Which city is the TokyoSydney C.W. Tang?

Output: Hong Kong

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which city is the TokyoSydney C.W. Tang?. ### Response: Hong Kong.


Instruction: Vivarelli, RomeCarsten Wagner, ZurichAngela Wang, Hong KongDonal Wesson, TempleJack Wetzels, NijmegenAdam Whaley-Connell, ColumbiaKeng-Thye Woo, SingaporeMotoko Yanagita, KyotoXueqing Yu, GuangzhouSuzuki Yusuke, TokyoSusue Qiu?

Output: z

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Vivarelli, RomeCarsten Wagner, ZurichAngela Wang, Hong KongDonal Wesson, TempleJack Wetzels, NijmegenAdam Whaley-Connell, ColumbiaKeng-Thye Woo, SingaporeMotoko Yanagita, KyotoXueqing Yu, GuangzhouSuzuki Yusuke, TokyoSusue Qiu?. ### Response: z.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 119 of 127?

Output: Patient trust

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 119 of 127?. ### Response: Patient trust.


Instruction: What does Fiscella K, Meldrum S, Franks P, et al. believe about patient trust?

Output: Is it related to patient -centered behavior of primary care physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Fiscella K, Meldrum S, Franks P, et al. believe about patient trust?. ### Response: Is it related to patient -centered behavior of primary care physicians.


Instruction: How to decide whether a clinical practice guideline is trustworthy?

Output: Standardization of Clinical Algorithms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How to decide whether a clinical practice guideline is trustworthy?. ### Response: Standardization of Clinical Algorithms.


Instruction: What is a new health system for physicians?

Output: Crossing the quality chasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new health system for physicians?. ### Response: Crossing the quality chasm.


Instruction: What year was Crossing the quality chasm: A new health system for the 21st century published?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Crossing the quality chasm: A new health system for the 21st century published?. ### Response: 2001.


Instruction: What is the name of the book that was published in Washington DC in 2001?

Output: National Academies Press

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that was published in Washington DC in 2001?. ### Response: National Academies Press.


Instruction: Who is the Society for Medical Decision Making Committee on Standardization of Clinical Algorithms?

Output: 19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Society for Medical Decision Making Committee on Standardization of Clinical Algorithms?. ### Response: 19.


Instruction: What is the name of the 1992 journal that dealt with cardiovascular risk assessment after four years?

Output: Med Decis Making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 1992 journal that dealt with cardiovascular risk assessment after four years?. ### Response: Med Decis Making.


Instruction: What was the PMID for Decis Making?

Output: 1573982

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID for Decis Making?. ### Response: 1573982.


Instruction: How long did it take to assess cardiovascular risk?

Output: four years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to assess cardiovascular risk?. ### Response: four years.


Instruction: What is the PMID for 26895071?

Output: PLoS One. 2016;1 1(2):e0147417. PMID: 26895071.  21. Angelow A, Schmidt CO, Dorr M, Chenot JF. Utility of repeat serum cholesterol measurements for assessment of cardiovascular risk in primary prevention. Eur J Prev Cardiol. Apr 2015;23(6):628- 635. PMID:  26170419

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for 26895071?. ### Response: PLoS One. 2016;1 1(2):e0147417. PMID: 26895071.  21. Angelow A, Schmidt CO, Dorr M, Chenot JF. Utility of repeat serum cholesterol measurements for assessment of cardiovascular risk in primary prevention. Eur J Prev Cardiol. Apr 2015;23(6):628- 635. PMID:  26170419.


Instruction: What is an example of a good strategy for monitoring lipids?

Output: Clinical Practice Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a good strategy for monitoring lipids?. ### Response: Clinical Practice Guideline.


Instruction: What is the name of the systematic review of strategies for monitoring lipid levels in patients at risk or with cardiovascular disease?

Output: Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of strategies for monitoring lipid levels in patients at risk or with cardiovascular disease?. ### Response: Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction.


Instruction: What was the PMID for this systematic review?

Output: 26680162

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID for this systematic review?. ### Response: 26680162.


Instruction: When did Health Technol Assess publish its findings?

Output: Dec 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Health Technol Assess publish its findings?. ### Response: Dec 2015.


Instruction: What is the frequency of testing for dyslipidemia?

Output: 23. Ontario HQ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the frequency of testing for dyslipidemia?. ### Response: 23. Ontario HQ.


Instruction: What was the PMID for this study?

Output: 30476079

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID for this study?. ### Response: 30476079.


Instruction: How did Howard G, McClure LA, Moy CS, et al. rate stroke risk?

Output: Self -Reported Stroke Risk Stratification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Howard G, McClure LA, Moy CS, et al. rate stroke risk?. ### Response: Self -Reported Stroke Risk Stratification.


Instruction: What is racial differences in stroke study?

Output: Self -Reported Stroke Risk Stratification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is racial differences in stroke study?. ### Response: Self -Reported Stroke Risk Stratification.


Instruction: What is the PMID of 28526763?

Output: 26960568

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID of 28526763?. ### Response: 26960568.


Instruction: Improvement in cardiovascular risk prediction with electronic health records?

Output: Is there improvement in risk prediction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Improvement in cardiovascular risk prediction with electronic health records?. ### Response: Is there improvement in risk prediction.


Instruction: How many cardiovascular risk algorithms were equalized after systematic recalibration?

Output: four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cardiovascular risk algorithms were equalized after systematic recalibration?. ### Response: four.


Instruction: How many prospective studies were included in the Eur Heart J. on Feb 14?

Output: 86

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prospective studies were included in the Eur Heart J. on Feb 14?. ### Response: 86.


Instruction: What is the PMID for this study?

Output: 30476079

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for this study?. ### Response: 30476079.


Instruction: What did Yadlowsky S, Hayward RA, Sussman JB, McClelland RL, Min YI, Basu S. Clinical implications of revised Pooled Cohort Equations for estimating atherosclerotic cardiovascular disease risk?

Output: 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Yadlowsky S, Hayward RA, Sussman JB, McClelland RL, Min YI, Basu S. Clinical implications of revised Pooled Cohort Equations for estimating atherosclerotic cardiovascular disease risk?. ### Response: 27.


Instruction: What was the PMID: 29868850?

Output: Ann Intern Med. Jul 3 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID: 29868850?. ### Response: Ann Intern Med. Jul 3 2018.


Instruction: What is the Veterans Affairs Cardiac Risk Score?

Output: Recalibrating the atherosclerotic cardiovascular disease score for applied use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Veterans Affairs Cardiac Risk Score?. ### Response: Recalibrating the atherosclerotic cardiovascular disease score for applied use.


Instruction: What is recalibrating the atherosclerotic cardiovascular disease score for applied use?

Output: The Veterans Affairs Cardiac Risk Score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recalibrating the atherosclerotic cardiovascular disease score for applied use?. ### Response: The Veterans Affairs Cardiac Risk Score.


Instruction: Med Care. Sep 2017; 55(9):864-870.

Output: Is there improvement in risk prediction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Med Care. Sep 2017; 55(9):864-870.. ### Response: Is there improvement in risk prediction.


Instruction: What is the official policy of the ACC and AHA?

Output: Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the official policy of the ACC and AHA?. ### Response: Guidelines.


Instruction: What provide recommendations applica-ble to patients with or at risk of developing cardiovas-cular disease?

Output: Intended UsePractice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provide recommendations applica-ble to patients with or at risk of developing cardiovas-cular disease?. ### Response: Intended UsePractice guidelines.


Instruction: What are guidelines intended to do?

Output: improve patients’ quality of care and align with patients’ interests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are guidelines intended to do?. ### Response: improve patients’ quality of care and align with patients’ interests.


Instruction: What is the goal of a guideline?

Output: improve patients’ quality of care and align with patients’ interests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of a guideline?. ### Response: improve patients’ quality of care and align with patients’ interests.


Instruction: Guidelines are intended to define practices meeting the needs of what?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Guidelines are intended to define practices meeting the needs of what?. ### Response: patients.


Instruction: Guideline recommended management is effective only when what is followed by healthcare providers and patients?

Output: Clinical Implementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Guideline recommended management is effective only when what is followed by healthcare providers and patients?. ### Response: Clinical Implementation.


Instruction: Adherence to recommendations can be enhanced by shared decision making.

Output: Clinical ImplementationGuideline recommended management is effective only when followed by healthcare providers and patients. Adherence to recommendations can be enhanced by shared decision making between healthcare providers and patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adherence to recommendations can be enhanced by shared decision making.. ### Response: Clinical ImplementationGuideline recommended management is effective only when followed by healthcare providers and patients. Adherence to recommendations can be enhanced by shared decision making between healthcare providers and patients.


Instruction: What can be enhanced by shared decision making between healthcare providers and patients?

Output: Adherence to recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be enhanced by shared decision making between healthcare providers and patients?. ### Response: Adherence to recommendations.


Instruction: What can patient engagement in selecting interventions based on individual values, preferences, and associated conditions and comorbidities?

Output: Adherence to recommendations can be enhanced by shared decision making between healthcare providers and patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can patient engagement in selecting interventions based on individual values, preferences, and associated conditions and comorbidities?. ### Response: Adherence to recommendations can be enhanced by shared decision making between healthcare providers and patients.


Instruction: What is the name of the organization that continuously reviews, updates, and modifies guideline methodology?

Output: The ACC/AHA Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that continuously reviews, updates, and modifies guideline methodology?. ### Response: The ACC/AHA Task Force on Clinical Practice Guidelines.


Instruction: What organization publishes standards on the basis of published standards?

Output: The ACC/AHA Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What organization publishes standards on the basis of published standards?. ### Response: The ACC/AHA Task Force on Clinical Practice Guidelines.


Instruction: How are presentation and delivery of guidelines reevaluated and modified?

Output: on the basis of evolving tech-nologies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are presentation and delivery of guidelines reevaluated and modified?. ### Response: on the basis of evolving tech-nologies.


Instruction: What is modified to facilitate optimal dissemination of information at the point of care to healthcare professionals?

Output: presentation and delivery of guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is modified to facilitate optimal dissemination of information at the point of care to healthcare professionals?. ### Response: presentation and delivery of guidelines.


Instruction: Given time constraints of busy healthcare providers and the need to limit text, the current guideline format delineates that each recommendation be supported by what?

Output: limited text

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Given time constraints of busy healthcare providers and the need to limit text, the current guideline format delineates that each recommendation be supported by what?. ### Response: limited text.


Instruction: How many words should each recommendation be?

Output: <250

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many words should each recommendation be?. ### Response: <250.


Instruction: What is the ideal length of text for a recommendation?

Output: <250 words

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ideal length of text for a recommendation?. ### Response: <250 words.


Instruction: How many hyperlinks to supporting evidence summary tables are there?

Output: <250 words

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hyperlinks to supporting evidence summary tables are there?. ### Response: <250 words.


Instruction: How long are revisions of the ACC/AHA guidelines commissioned?

Output: 6-year cycles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long are revisions of the ACC/AHA guidelines commissioned?. ### Response: 6-year cycles.


Instruction: How is an analysis of the value of a drug, device, or intervention performed?

Output: in accordance with the ACC/AHA methodology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is an analysis of the value of a drug, device, or intervention performed?. ### Response: in accordance with the ACC/AHA methodology.


Instruction: How long does it take for the Task Force to publish new, potentially practice-changing study results?

Output: time constraints

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for the Task Force to publish new, potentially practice-changing study results?. ### Response: time constraints.


Instruction: Who will evaluate new study results that are relevant to an existing or new drug, device, or management strategy?

Output: the Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who will evaluate new study results that are relevant to an existing or new drug, device, or management strategy?. ### Response: the Task Force.