Instruction: What type of tachycardia are beta blockers and calcium channel blockers used for?

Output: focal atrial tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of tachycardia are beta blockers and calcium channel blockers used for?. ### Response: focal atrial tachycardia.


Instruction: Where can you find the latest version of this article?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the latest version of this article?. ### Response: http://ahajournals.org.


Instruction: When was this article published?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 23, 2023.


Instruction: What is the name of the publication that was published in 2012?

Output: kidney-international

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the publication that was published in 2012?. ### Response: kidney-international.


Instruction: When was the last issue of the Kidney International Journal published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of the Kidney International Journal published?. ### Response: 2012.


Instruction: What is the ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: 2019.


Instruction: What was the 10-year risk of “hard ASCVD”?

Output: 8.7%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 10-year risk of “hard ASCVD”?. ### Response: 8.7%,.


Instruction: How much was the risk of the expanded asCVD end-point that included coronary revascularization?

Output: 10%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the risk of the expanded asCVD end-point that included coronary revascularization?. ### Response: 10%..


Instruction: What percentage included coronary revascularization?

Output: 10%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage included coronary revascularization?. ### Response: 10%..


Instruction: After 5.6 years, those assigned to rosuvastatin 10 mg per day showed significant absolute risk reduction in both co-primary end-points with an acceptable safety record?

Output: S4.3-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After 5.6 years, those assigned to rosuvastatin 10 mg per day showed significant absolute risk reduction in both co-primary end-points with an acceptable safety record?. ### Response: S4.3-9.


Instruction: What was the median follow-up of 1.9 years?

Output: those assigned to a high-intensity statin dose of rosuvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median follow-up of 1.9 years?. ### Response: those assigned to a high-intensity statin dose of rosuvastatin.


Instruction: What was the name of the RCT that evaluated rosuvastatin in a high-intensity statin dose?

Output: JUPITER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the RCT that evaluated rosuvastatin in a high-intensity statin dose?. ### Response: JUPITER.


Instruction: What did the participants in the JUPITER RCT achieve in relation to LDL-C lowering and ASCVD?

Output: greater reductions in ASCVD outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the participants in the JUPITER RCT achieve in relation to LDL-C lowering and ASCVD?. ### Response: greater reductions in ASCVD outcomes.


Instruction: What is the net benefit of LDL-C-lowering therapy greater with greater reductions in?

Output: ASCVD outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the net benefit of LDL-C-lowering therapy greater with greater reductions in?. ### Response: ASCVD outcomes.


Instruction: What is reasonable to use a high-intensity statin to lower by 50%?

Output: LDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to use a high-intensity statin to lower by 50%?. ### Response: LDL-C.


Instruction: What percentage of LDL-C is lower?

Output: ≥50%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of LDL-C is lower?. ### Response: ≥50%..


Instruction: What is the 10-year risk of ASCVD?

Output: ≥20%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 10-year risk of ASCVD?. ### Response: ≥20%..


Instruction: Who enrolled men 50 and women 60 years of age with high-sensitivity C-reactive pro-tein values?

Output: JUPITER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who enrolled men 50 and women 60 years of age with high-sensitivity C-reactive pro-tein values?. ### Response: JUPITER.


Instruction: How many mg per day of rosuvastatin were participants randomly assigned to?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg per day of rosuvastatin were participants randomly assigned to?. ### Response: 20.


Instruction: What was the median LDL-C reduc-tion of rosuvastatin?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median LDL-C reduc-tion of rosuvastatin?. ### Response: 50%.


Instruction: How long did it take for ASCVD risk to be reduced?

Output: 1.9 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for ASCVD risk to be reduced?. ### Response: 1.9 years.


Instruction: What did the USPSTF systematic review of statin therapy show?

Output: reduced risk of all-cause and cardio-vascular mortality and ASCVD events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the USPSTF systematic review of statin therapy show?. ### Response: reduced risk of all-cause and cardio-vascular mortality and ASCVD events.


Instruction: What did a review of statin therapy in primary prevention show reduced risk of?

Output: all-cause and cardio-vascular mortality and ASCVD events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a review of statin therapy in primary prevention show reduced risk of?. ### Response: all-cause and cardio-vascular mortality and ASCVD events.


Instruction: What did the review show greater absolute benefits in those at greater base-line risk?

Output: statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the review show greater absolute benefits in those at greater base-line risk?. ### Response: statin therapy.


Instruction: What is the need for aggressive and safe risk reduction in the highest-risk groups?

Output: follow-up LDL-C testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the need for aggressive and safe risk reduction in the highest-risk groups?. ### Response: follow-up LDL-C testing.


Instruction: What is needed to determine adherence and adequacy of effect of the statin prescribed?

Output: follow-up LDL-C testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to determine adherence and adequacy of effect of the statin prescribed?. ### Response: follow-up LDL-C testing.


Instruction: Most patients 40 to 75 years of age with diabe-tes are at intermediate or high risk?

Output: ASCVD events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most patients 40 to 75 years of age with diabe-tes are at intermediate or high risk?. ### Response: ASCVD events.


Instruction: How many double-blind primary-prevention RCTs showed significant reductions in ASCVD events in large cohorts with diabetes in this age range?

Output: Three of 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many double-blind primary-prevention RCTs showed significant reductions in ASCVD events in large cohorts with diabetes in this age range?. ### Response: Three of 4.


Instruction: What did a meta-analysis of these trials find associated with moderate-intensity statin therapy?

Output: a risk reduction of 25%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a meta-analysis of these trials find associated with moderate-intensity statin therapy?. ### Response: a risk reduction of 25%,.


Instruction: What was associated with a risk reduction of 25%,S4.3-13?

Output: moderate-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a risk reduction of 25%,S4.3-13?. ### Response: moderate-intensity statin therapy.


Instruction: What is indicated for primary prevention in patients 40 to 75 years old?

Output: moderate-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated for primary prevention in patients 40 to 75 years old?. ### Response: moderate-intensity statin therapy.


Instruction: What is indicated for primary prevention in patients 40 to 75 years of age?

Output: moderate-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated for primary prevention in patients 40 to 75 years of age?. ### Response: moderate-intensity statin therapy.


Instruction: What is the most common medical complication inaSAH?

Output: Fever

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common medical complication inaSAH?. ### Response: Fever.


Instruction: What has fever of noninfectious origin been associated with?

Output: severity of injury, amount ofhemorrhage, and development of vasospasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has fever of noninfectious origin been associated with?. ### Response: severity of injury, amount ofhemorrhage, and development of vasospasm.


Instruction: What has been associated with severity of injury, amount of hemorrhage, and development of vasospasm?

Output: The presence of fever of noninfectious (central)origin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been associated with severity of injury, amount of hemorrhage, and development of vasospasm?. ### Response: The presence of fever of noninfectious (central)origin.


Instruction: What may be a marker of a systemic inflammatory state triggered?

Output: fever

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be a marker of a systemic inflammatory state triggered?. ### Response: fever.


Instruction: When did Stroke June 2012 occur?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Stroke June 2012 occur?. ### Response: April 28, 2023.


Instruction: What should be administered preoperatively to patients undergoing CABG?

Output: Non–enteric-coated aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be administered preoperatively to patients undergoing CABG?. ### Response: Non–enteric-coated aspirin.


Instruction: How much aspirin should be given daily?

Output: 81 mg to 325 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much aspirin should be given daily?. ### Response: 81 mg to 325 mg.


Instruction: What is the Level of Evidence?

Output: B)Class IIb1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence?. ### Response: B)Class IIb1.


Instruction: What should be discontinued for at least 5 days before surgery in patients referred for elective CABG?

Output: clopidogrel and ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be discontinued for at least 5 days before surgery in patients referred for elective CABG?. ### Response: clopidogrel and ticagrelor.


Instruction: How long should clopidogrel and ticagrelor be discontinued before surgery?

Output: 5 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should clopidogrel and ticagrelor be discontinued before surgery?. ### Response: 5 days.


Instruction: When should prasugrel be discontinued?

Output: 7 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should prasugrel be discontinued?. ### Response: 7 days.


Instruction: How long should clopidogrel and ticagrelor be discontinued in patients referred for urgent CABG?

Output: 1 to 4 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should clopidogrel and ticagrelor be discontinued in patients referred for urgent CABG?. ### Response: 1 to 4 days.


Instruction: What should be discontinued for at least 24 hours to reduce major bleeding?

Output: clopidogrel and ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be discontinued for at least 24 hours to reduce major bleeding?. ### Response: clopidogrel and ticagrelor.


Instruction: When should short acting intravenous GP IIb/IIIa inhibitors be discontinued?

Output: 2 to 4 hours before surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should short acting intravenous GP IIb/IIIa inhibitors be discontinued?. ### Response: 2 to 4 hours before surgery.


Instruction: What should be discontinued for at least 2 to 4 hours before surgery?

Output: short-acting intrave-nous GP IIb/IIIa inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be discontinued for at least 2 to 4 hours before surgery?. ### Response: short-acting intrave-nous GP IIb/IIIa inhibitors.


Instruction: How long should abciximab be discontinued?

Output: 12 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should abciximab be discontinued?. ### Response: 12 hours.


Instruction: What is the level of evidence?

Output: B)Class IIb1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence?. ### Response: B)Class IIb1.


Instruction: What is performed in 7% to 13% of patients hospitalized with NSTE-ACS?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed in 7% to 13% of patients hospitalized with NSTE-ACS?. ### Response: CABG.


Instruction: How long after clopidogrel or ticagrelor has been discontinued is it reasonable to perform surgery?

Output: less than 5 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after clopidogrel or ticagrelor has been discontinued is it reasonable to perform surgery?. ### Response: less than 5 days.


Instruction: What percentage of NSTEMI patients undergo CABG?

Output: one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of NSTEMI patients undergo CABG?. ### Response: one third.


Instruction: What percentage of patients with NSTEMI undergo CABG within 48 hours of hospital admission?

Output: Approximately one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with NSTEMI undergo CABG within 48 hours of hospital admission?. ### Response: Approximately one third.


Instruction: What was performed at a median time of 73 hours after admission in these patients?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was performed at a median time of 73 hours after admission in these patients?. ### Response: CABG.


Instruction: How much is the in-hospital mortality in patients undergoing CABG?

Output: 3.7%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much is the in-hospital mortality in patients undergoing CABG?. ### Response: 3.7%..


Instruction: What is the percentage of patients with NSTEMI undergoing CABG?

Output: one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of patients with NSTEMI undergoing CABG?. ### Response: one third.


Instruction: What is given in the 2011 CABG CPG?

Output: Recommendations for management of patients treated with oral and intravenous antiplatelet agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is given in the 2011 CABG CPG?. ### Response: Recommendations for management of patients treated with oral and intravenous antiplatelet agents.


Instruction: Preoperative aspirin reduces what?

Output: operative morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preoperative aspirin reduces what?. ### Response: operative morbidity and mortality.


Instruction: How can CABG be performed safely?

Output: aspirin therapy with only a modest increase in bleeding risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can CABG be performed safely?. ### Response: aspirin therapy with only a modest increase in bleeding risk.


Instruction: What can be performed safely in patients on aspirin therapy?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be performed safely in patients on aspirin therapy?. ### Response: CABG.


Instruction: What is associated with an increase in post-CABG bleeding and the need for transfusion?

Output: The use of P2Y12 inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with an increase in post-CABG bleeding and the need for transfusion?. ### Response: The use of P2Y12 inhibitors.


Instruction: Clopidogrel and ticagrelor should be discontinued at least at least what?

Output: 5 days before surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Clopidogrel and ticagrelor should be discontinued at least at least what?. ### Response: 5 days before surgery.


Instruction: When should clopidogrel and ticagrelor be discontinued?

Output: 5 days before surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should clopidogrel and ticagrelor be discontinued?. ### Response: 5 days before surgery.


Instruction: What should prasugrel be discontinued at least 7 days before surgery in patients referred for elective CABG?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should prasugrel be discontinued at least 7 days before surgery in patients referred for elective CABG?. ### Response: clopidogrel.


Instruction: When should timing of CABG in patients with NSTE-ACS treated with a P2Y12 inhibitor330 reflect?

Output: a balance of the potential increase in bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should timing of CABG in patients with NSTE-ACS treated with a P2Y12 inhibitor330 reflect?. ### Response: a balance of the potential increase in bleeding.


Instruction: What should inhibitor330 reflect a balance of the potential increase in bleeding against the potential benefits of not delaying surgery 5 to 7 days?

Output: P2Y12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should inhibitor330 reflect a balance of the potential increase in bleeding against the potential benefits of not delaying surgery 5 to 7 days?. ### Response: P2Y12.


Instruction: What is increased when CABG is performed 24 hours after dis-continuation of clopidogrel?

Output: The risk of major bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is increased when CABG is performed 24 hours after dis-continuation of clopidogrel?. ### Response: The risk of major bleeding complications.


Instruction: How long after discontinuation of clopidogrel is the incidence of life-threatening bleeding not significantly increased?

Output: 1 to 4 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after discontinuation of clopidogrel is the incidence of life-threatening bleeding not significantly increased?. ### Response: 1 to 4 days.


Instruction: What is an increase in blood transfusions?

Output: the incidence of life-threatening bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increase in blood transfusions?. ### Response: the incidence of life-threatening bleeding.


Instruction: What does subsegmental PE stand for?

Output: noinvolvement of more proxi mal pulmonary arteries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does subsegmental PE stand for?. ### Response: noinvolvement of more proxi mal pulmonary arteries.


Instruction: What is the grade of anticoagulation used for in patients with low risk for VTE?

Output: Grade2C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the grade of anticoagulation used for in patients with low risk for VTE?. ### Response: Grade2C.


Instruction: What should be done to exclude proximal DVT?

Output: US imaging of the deep veins of both leg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be done to exclude proximal DVT?. ### Response: US imaging of the deep veins of both leg.


Instruction: What can be supplemented by serial US imaging of both legs?

Output: Clinicalsurveillance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be supplemented by serial US imaging of both legs?. ### Response: Clinicalsurveillance.


Instruction: What is the purpose of US imaging of the proximal deep veins of both legs?

Output: to detect evolvingDVT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of US imaging of the proximal deep veins of both legs?. ### Response: to detect evolvingDVT.


Instruction: What is more likely for patients and physicians to opt for clinical surveillance over anticoagulation?

Output: there is good cardiopulmonary reserve or a high risk ofbleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more likely for patients and physicians to opt for clinical surveillance over anticoagulation?. ### Response: there is good cardiopulmonary reserve or a high risk ofbleeding.


Instruction: How long did LMWH last in the hospital?

Output: 3 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did LMWH last in the hospital?. ### Response: 3 days.


Instruction: How many observationalstudies were there in AT9?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many observationalstudies were there in AT9?. ### Response: 15.


Instruction: How many observationalstudies evaluated acute PE out of the hospital?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many observationalstudies evaluated acute PE out of the hospital?. ### Response: 15.


Instruction: How many of thesestudies were prospective?

Output: 9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of thesestudies were prospective?. ### Response: 9.


Instruction: No further randomized trials have evaluated out-of-hospitaltreatment of acute PE?

Output: AT9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No further randomized trials have evaluated out-of-hospitaltreatment of acute PE?. ### Response: AT9.


Instruction: What has been included in recent meta-analyses that addressed treatment of acute PE outof the hospital?

Output: Several additional prospectiveand retrospective observational studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been included in recent meta-analyses that addressed treatment of acute PE outof the hospital?. ### Response: Several additional prospectiveand retrospective observational studies.


Instruction: What did studies that evaluated NOACs for the acute treatment ofPE not report?

Output: the proportion of patients who weretreated entirely out of hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did studies that evaluated NOACs for the acute treatment ofPE not report?. ### Response: the proportion of patients who weretreated entirely out of hospital.


Instruction: What did the acute treatment ofPE not report?

Output: the proportion of patients who weretreated entirely out of hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the acute treatment ofPE not report?. ### Response: the proportion of patients who weretreated entirely out of hospital.


Instruction: What was the proportion of patients who were treated entirely out of hospital?

Output: 122

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the proportion of patients who were treated entirely out of hospital?. ### Response: 122.


Instruction: What is indi-cated to prevent SCD?

Output: an ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indi-cated to prevent SCD?. ### Response: an ICD.


Instruction: What has proven to be highly effective in eliminating the repetitive PVCs which induce VF?

Output: Catheter ablation of the triggering focus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has proven to be highly effective in eliminating the repetitive PVCs which induce VF?. ### Response: Catheter ablation of the triggering focus.


Instruction: What is highly effective in eliminating the repetitive PVCs which induce VF in these patients?

Output: Catheter ablation of the triggering focus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is highly effective in eliminating the repetitive PVCs which induce VF in these patients?. ### Response: Catheter ablation of the triggering focus.


Instruction: What percentage of patients undergoing catheter ablation of idio-pathic VF experi-enced VF recurrence at a median follow-up of 4 months?

Output: 18%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients undergoing catheter ablation of idio-pathic VF experi-enced VF recurrence at a median follow-up of 4 months?. ### Response: 18%).


Instruction: How long was the median follow-up?

Output: 4 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the median follow-up?. ### Response: 4 months.


Instruction: How many patients underwent repeat ablation without VF recurrence?

Output: Five

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent repeat ablation without VF recurrence?. ### Response: Five.


Instruction: What is very effective in idiopathic VF?

Output: catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is very effective in idiopathic VF?. ### Response: catheter ablation.


Instruction: What should a patient be protected with?

Output: an ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient be protected with?. ### Response: an ICD.


Instruction: Why is the subcuta-neous ICD not a good therapy for these patients?

Output: higher risk of T-wave over -sensing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the subcuta-neous ICD not a good therapy for these patients?. ### Response: higher risk of T-wave over -sensing.


Instruction: What may be initiated by PVCs that arise from the outflow tracts?

Output: Idiopathic VF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be initiated by PVCs that arise from the outflow tracts?. ### Response: Idiopathic VF.


Instruction: What are PVCs that arise from the outflow tracts or the His-Purkinje system within the right or left ventricle?

Output: Idiopathic VF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are PVCs that arise from the outflow tracts or the His-Purkinje system within the right or left ventricle?. ### Response: Idiopathic VF.


Instruction: What are clusters of VF episodes called?

Output: electrical storm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are clusters of VF episodes called?. ### Response: electrical storm.


Instruction: What is the ablation target for PVCs from the Purkinje system?

Output: a high-frequency Purkinje potential pre-ceding the PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ablation target for PVCs from the Purkinje system?. ### Response: a high-frequency Purkinje potential pre-ceding the PVCs.


Instruction: What is a consistent QRS morphol-ogy and short coupling interval?

Output: PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a consistent QRS morphol-ogy and short coupling interval?. ### Response: PVCs.


Instruction: What are induced by short-coupled PVCs arising from the outflow tracts?

Output: episodes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are induced by short-coupled PVCs arising from the outflow tracts?. ### Response: episodes.


Instruction: The ablation target is the site of what?

Output: earliest ventricular activation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ablation target is the site of what?. ### Response: earliest ventricular activation.


Instruction: Patients with idiopathic VF often have periods of frequent VT/VF interspersed with peri-ods of relative quiescence?

Output: Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with idiopathic VF often have periods of frequent VT/VF interspersed with peri-ods of relative quiescence?. ### Response: Patients.


Instruction: To maximize the probability of successful ablation, the proce-dure is best performed during what period?

Output: periods of frequent PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To maximize the probability of successful ablation, the proce-dure is best performed during what period?. ### Response: periods of frequent PVCs.


Instruction: When is the proce-dure best performed?

Output: during periods of frequent PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the proce-dure best performed?. ### Response: during periods of frequent PVCs.


Instruction: What may be ame-nable to ablation if frequent PVCs with a consistent QRS are present?

Output: Less-frequent episodes of VF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be ame-nable to ablation if frequent PVCs with a consistent QRS are present?. ### Response: Less-frequent episodes of VF.


Instruction: When are late recurrences observed in approximately 10% of cases?

Output: implantation of an ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When are late recurrences observed in approximately 10% of cases?. ### Response: implantation of an ICD.


Instruction: What percentage of patients have late recurrences?

Output: 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have late recurrences?. ### Response: 10%.


Instruction: What is one of the risks of catheter ablation?

Output: bleeding at the site of arterial or venous access

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the risks of catheter ablation?. ### Response: bleeding at the site of arterial or venous access.


Instruction: What is the risk of pericardial tamponade?

Output: small

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of pericardial tamponade?. ### Response: small.


Instruction: What can therapy with quinidine suppress in some patients?

Output: recurrent VF episodes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can therapy with quinidine suppress in some patients?. ### Response: recurrent VF episodes.


Instruction: Where are the references that support the recommendations summarized?

Output: Online Data Supplement 50

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the references that support the recommendations summarized?. ### Response: Online Data Supplement 50.


Instruction: What is B-NR1 for patients who require arrhythmia suppression for symptoms or declining ventricular function suspected to be due to frequent PVCs?

Output: COR LOE RecommendationsI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is B-NR1 for patients who require arrhythmia suppression for symptoms or declining ventricular function suspected to be due to frequent PVCs?. ### Response: COR LOE RecommendationsI.


Instruction: What percentage of beats are generally >15%?

Output: PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of beats are generally >15%?. ### Response: PVCs.


Instruction: How many societies make up the Task Force on Cardiovascular Disease Prevention in Clinical Practice?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many societies make up the Task Force on Cardiovascular Disease Prevention in Clinical Practice?. ### Response: 10.


Instruction: What is the name of the group whose special contribution was made by the European Association for Cardiovascular Prevention & Rehabilitation?

Output: European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group whose special contribution was made by the European Association for Cardiovascular Prevention & Rehabilitation?. ### Response: European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice.


Instruction: What is EACPR?

Output: European Association for Cardiovascular Prevention & Rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EACPR?. ### Response: European Association for Cardiovascular Prevention & Rehabilitation.


Instruction: What is the association of objectively measured sedentary behavior with mortality?

Output: cardiovascular morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of objectively measured sedentary behavior with mortality?. ### Response: cardiovascular morbidity.


Instruction: What is the association of objectively measured sedentary behaviour and physical activity with cardiovas-cular disease risk?

Output: adult cardiometabolic health and mortal-ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of objectively measured sedentary behaviour and physical activity with cardiovas-cular disease risk?. ### Response: adult cardiometabolic health and mortal-ity.


Instruction: What is a meta-analysis of the relationship between physical activity and risk of heart failure?

Output: Dose-response relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of the relationship between physical activity and risk of heart failure?. ### Response: Dose-response relationship.


Instruction: How does light-intensity physical activity associate with cardiovascular morbidity and mortality?

Output: Association of objectively measured sedentary behaviour and physical activity with cardiovas-cular disease risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does light-intensity physical activity associate with cardiovascular morbidity and mortality?. ### Response: Association of objectively measured sedentary behaviour and physical activity with cardiovas-cular disease risk.


Instruction: What is a science advisory from the American Heart Association?

Output: Sedentary behavior and cardiovascular morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a science advisory from the American Heart Association?. ### Response: Sedentary behavior and cardiovascular morbidity and mortality.


Instruction: How does Sedentary Behavior and Cardiovascular Mortality compare?

Output: waist-hip ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Sedentary Behavior and Cardiovascular Mortality compare?. ### Response: waist-hip ratio.


Instruction: How does light-intensity physical activity associate with adult cardiometabolic health and mortal-ity?

Output: Systematic review with meta-analysis of experimental and observa-tional studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does light-intensity physical activity associate with adult cardiometabolic health and mortal-ity?. ### Response: Systematic review with meta-analysis of experimental and observa-tional studies.


Instruction: What is the name of the systematic review with meta-analysis of experimental and observa-tional studies?

Output: S4.1-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review with meta-analysis of experimental and observa-tional studies?. ### Response: S4.1-2.


Instruction: When did the Br J Sports Med. 2018 Apr 25. [Epub ahead of print]4. What is another factor that affects cardiovascular risk?

Output: Sedentary behavior and cardiovascular morbidity and mortality: a science advisory from the American Heart Association. Circulation. 2016;134:e262–79. S3.2-31.  Chastin SFM, De Craemer M, De Cocker K, et al. How does light-intensity physical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Br J Sports Med. 2018 Apr 25. [Epub ahead of print]4. What is another factor that affects cardiovascular risk?. ### Response: Sedentary behavior and cardiovascular morbidity and mortality: a science advisory from the American Heart Association. Circulation. 2016;134:e262–79. S3.2-31.  Chastin SFM, De Craemer M, De Cocker K, et al. How does light-intensity physical activity.


Instruction: What is RISK4.1?

Output: Obesity and Being Overweight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is RISK4.1?. ### Response: Obesity and Being Overweight.


Instruction: What is the name of the draft evidence review for weight loss to prevent obesity-related morbidity and mortality in adults?

Output: behavioral interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the draft evidence review for weight loss to prevent obesity-related morbidity and mortality in adults?. ### Response: behavioral interventions.


Instruction: Where is the Kaiser Permanente Center for Health Research located?

Output: Portland, OR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Kaiser Permanente Center for Health Research located?. ### Response: Portland, OR.


Instruction: Where is the AHRQ Publication No. 18-05239-EF-1 located?

Output: Kaiser Permanente Research Affiliates Evidence-based Practice Center, Kaiser Permanente Center for Health Research: Portland, OR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the AHRQ Publication No. 18-05239-EF-1 located?. ### Response: Kaiser Permanente Research Affiliates Evidence-based Practice Center, Kaiser Permanente Center for Health Research: Portland, OR.


Instruction: What is the name of the publication that is available at: https://www.uspreventiveservicestask-force.org/Page/Document/draft-evidence-review/obesity-in-adults-interventions1. Accessed January 5, 2019.

Output: AHRQ Publication No. 18-05239-EF-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the publication that is available at: https://www.uspreventiveservicestask-force.org/Page/Document/draft-evidence-review/obesity-in-adults-interventions1. Accessed January 5, 2019.. ### Response: AHRQ Publication No. 18-05239-EF-1.


Instruction: What are the effects of weight loss interventions for adults who are obese?

Output: mortality, cardiovascular dis-ease, and cancer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects of weight loss interventions for adults who are obese?. ### Response: mortality, cardiovascular dis-ease, and cancer.


Instruction: What is a systematic review and meta-analysis?

Output: experimental and observa-tional studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis?. ### Response: experimental and observa-tional studies.


Instruction: What is the BMJ 2017 359:j4849?

Output: systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BMJ 2017 359:j4849?. ### Response: systematic review and meta-analysis.


Instruction: How does Coronary heart disease inci-dence in women differ from waist circumference?

Output: within categories of body mass index

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Coronary heart disease inci-dence in women differ from waist circumference?. ### Response: within categories of body mass index.


Instruction: What is the best discrimi-nator for waist circumference and waist-hip ratio?

Output: Body mass index

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the best discrimi-nator for waist circumference and waist-hip ratio?. ### Response: Body mass index.


Instruction: When did South Carolina study the association with hypertension and diabetes in African American women?

Output: 2007–2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did South Carolina study the association with hypertension and diabetes in African American women?. ### Response: 2007–2009.


Instruction: What was the name of the study in South Carolina?

Output: Warren TY, Wilcox S, Dowda M, et al. Independent association of waist circumference with hypertension and diabetes in African American women, South Carolina, 2007–2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study in South Carolina?. ### Response: Warren TY, Wilcox S, Dowda M, et al. Independent association of waist circumference with hypertension and diabetes in African American women, South Carolina, 2007–2009.


Instruction: What is the best indicator of cardiovascular disease mortality risk?

Output: waist-hip ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the best indicator of cardiovascular disease mortality risk?. ### Response: waist-hip ratio.


Instruction: How many participants participated in an individual-participant meta-analysis?

Output: 82 864

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants participated in an individual-participant meta-analysis?. ### Response: 82 864.


Instruction: What is reasonable to monitor for the development of arterial vasospasm?

Output: Transcranial Doppler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to monitor for the development of arterial vasospasm?. ### Response: Transcranial Doppler.


Instruction: What is a class III; Level of Evidence B?

Output: Prophylactic hypervolemia or balloon angioplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class III; Level of Evidence B?. ### Response: Prophylactic hypervolemia or balloon angioplasty.


Instruction: What can be useful to identify regions of potential brainischemia?

Output: Perfusion imaging with CT or magnetic resonance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be useful to identify regions of potential brainischemia?. ### Response: Perfusion imaging with CT or magnetic resonance.


Instruction: What is recommended for patients with DCI unless blood pressure is elevated atbaseline or cardiac status precludes it?

Output: Induction of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with DCI unless blood pressure is elevated atbaseline or cardiac status precludes it?. ### Response: Induction of hypertension.


Instruction: What type of therapy is reasonable in patients withsymptomatic cerebral vasospasm?

Output: Cerebral angioplasty and/or selective intra-arterialvasodilator therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is reasonable in patients withsymptomatic cerebral vasospasm?. ### Response: Cerebral angioplasty and/or selective intra-arterialvasodilator therapy.


Instruction: What is the Class IIa; Level of Evidence B?

Output: Cerebral angioplasty and/or selective intra-arterialvasodilator therapy is reasonable in patients withsymptomatic cerebral vasospasm, particularly thosewho are not rapidly responding to hypertensivetherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class IIa; Level of Evidence B?. ### Response: Cerebral angioplasty and/or selective intra-arterialvasodilator therapy is reasonable in patients withsymptomatic cerebral vasospasm, particularly thosewho are not rapidly responding to hypertensivetherapy.


Instruction: What percentage of patients with aSAH havecute hydrocephalus?

Output: 15% to 87%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with aSAH havecute hydrocephalus?. ### Response: 15% to 87%.


Instruction: What percent of patients have chronic shunt-dependent hydrocephaly?

Output: 8.9% to 48%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percent of patients have chronic shunt-dependent hydrocephaly?. ### Response: 8.9% to 48%.


Instruction: How many randomized, controlled trials are there regarding the management of hydrocelephalus associ-ated withaSAHA?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized, controlled trials are there regarding the management of hydrocelephalus associ-ated withaSAHA?. ### Response: 1.


Instruction: How is acute hydrocephalus associated with aSAH usually managed?

Output: external ventricular drainage (EVD) orlumbar drainage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is acute hydrocephalus associated with aSAH usually managed?. ### Response: external ventricular drainage (EVD) orlumbar drainage.


Instruction: What is external ventricular drainage orlumbar drainage?

Output: EVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is external ventricular drainage orlumbar drainage?. ### Response: EVD.


Instruction: What is EVD for patients with aSAH-associatedhydrocephalus generally associated with?

Output: neurological im-provement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EVD for patients with aSAH-associatedhydrocephalus generally associated with?. ### Response: neurological im-provement.


Instruction: What has been studied in 3 retrospective case series?

Output: The risk of aneurysm rebleeding with EVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been studied in 3 retrospective case series?. ### Response: The risk of aneurysm rebleeding with EVD.


Instruction: How many studies found no increased risk of rebleeding?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies found no increased risk of rebleeding?. ### Response: 2.


Instruction: What is the risk of tissue shift after placement of a lumbardrain in patients with aSAH-associatedhydrocephalus?

Output: Thetheoretical risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of tissue shift after placement of a lumbardrain in patients with aSAH-associatedhydrocephalus?. ### Response: Thetheoretical risk.


Instruction: What should be considered when deciding what method of cerebrospinalfluid diversion to use?

Output: Thetheoretical risk of tissue shift after placement of a lumbardrain in patients with severe intracranial hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered when deciding what method of cerebrospinalfluid diversion to use?. ### Response: Thetheoretical risk of tissue shift after placement of a lumbardrain in patients with severe intracranial hypertension.


Instruction: When obstructive hydroceph-alus is suspected, an EVD should be preferred?

Output: rebleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When obstructive hydroceph-alus is suspected, an EVD should be preferred?. ### Response: rebleeding.


Instruction: Preliminarydata have suggested that lumbar drainage is associated with what?

Output: reduced incidence of vasospasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preliminarydata have suggested that lumbar drainage is associated with what?. ### Response: reduced incidence of vasospasm.


Instruction: What type of drainage is associated with reduced incidence of vasospasm?

Output: lumbar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of drainage is associated with reduced incidence of vasospasm?. ### Response: lumbar.


Instruction: Serial lumbar punctures to manage acute aSAH-associated hydrocephalus have been described as what?

Output: safe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Serial lumbar punctures to manage acute aSAH-associated hydrocephalus have been described as what?. ### Response: safe.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 75 of 127 E. Recommendation Categorization A set of recommendation categories was adapted from what?

Output: NICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 75 of 127 E. Recommendation Categorization A set of recommendation categories was adapted from what?. ### Response: NICE.


Instruction: What was used to account for the various ways in which recommendations could have been updated from the 2014 VA/DoD Dyslipidemia CPG?

Output: Recommendation Categories and Definitions  A set of recommendation categories was adapted from those used by NICE. [8,9] These categories, along with their corresponding definitions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to account for the various ways in which recommendations could have been updated from the 2014 VA/DoD Dyslipidemia CPG?. ### Response: Recommendation Categories and Definitions  A set of recommendation categories was adapted from those used by NICE. [8,9] These categories, along with their corresponding definitions.


Instruction: What can be found in Table A-5?

Output: The categories and definitions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be found in Table A-5?. ### Response: The categories and definitions.


Instruction: In Table A-5?

Output: categories and definitions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In Table A-5?. ### Response: categories and definitions.


Instruction: Evidence Reviewed Recommendation Category Definition Reviewed New-added New recommendation following review of the evidence What has been carried over to the updated CPG?

Output: Recommendation from previous CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence Reviewed Recommendation Category Definition Reviewed New-added New recommendation following review of the evidence What has been carried over to the updated CPG?. ### Response: Recommendation from previous CPG.


Instruction: What has been carried over to the updated CPG that has been changed following review of the evidence?

Output: Recommendation from previous CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been carried over to the updated CPG that has been changed following review of the evidence?. ### Response: Recommendation from previous CPG.


Instruction: What has the evidence been r eviewed but the recommendation wa s not changed?

Output: Recommendation from previous CPG that has been carried forward to the updated CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has the evidence been r eviewed but the recommendation wa s not changed?. ### Response: Recommendation from previous CPG that has been carried forward to the updated CPG.


Instruction: What has been carried forward to the updated CPG where the evidence has been reviewed and a minor amendment was made?

Output: Recommendation from previous CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been carried forward to the updated CPG where the evidence has been reviewed and a minor amendment was made?. ### Response: Recommendation from previous CPG.


Instruction: What was removed from previous CPG that has been removed?

Output: Recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was removed from previous CPG that has been removed?. ### Response: Recommendation.


Instruction: Recommendation from previous CPG that has been removed based on review of the evidence Not reviewed Not changed Recommandation that was carried forward to the updated CPG but for which the evidence has not been reviewed?

Output: Amended

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recommendation from previous CPG that has been removed based on review of the evidence Not reviewed Not changed Recommandation that was carried forward to the updated CPG but for which the evidence has not been reviewed?. ### Response: Amended.


Instruction: What has not been reviewed Amended Recommendation from previous CPG that has been carried forward to the updated CPG where the evidence hasn't been reviewed and a minor amendment has been made What has been removed because it was deemed out of date?

Output: the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been reviewed Amended Recommendation from previous CPG that has been carried forward to the updated CPG where the evidence hasn't been reviewed and a minor amendment has been made What has been removed because it was deemed out of date?. ### Response: the evidence.


Instruction: What was removed because it was out of scope for the updated CPG?

Output: Recommendation from previous CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was removed because it was out of scope for the updated CPG?. ### Response: Recommendation from previous CPG.


Instruction: What was adapted from the NICE guideline manual?

Output: recommendation categories

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was adapted from the NICE guideline manual?. ### Response: recommendation categories.


Instruction: What is NICE: National Institute for Health and Care Excellence?

Output: clinical practice guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE: National Institute for Health and Care Excellence?. ### Response: clinical practice guideline.


Instruction: What were recommendations first categorized by whether or not they were based on an updated review of?

Output: the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were recommendations first categorized by whether or not they were based on an updated review of?. ### Response: the evidence.


Instruction: What were recommendations categorized as if evidence had been reviewed?

Output: “New -added,” “New -replaced,” “Not changed,” “Amended,” or “Deleted.”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were recommendations categorized as if evidence had been reviewed?. ### Response: “New -added,” “New -replaced,” “Not changed,” “Amended,” or “Deleted.”.


Instruction: What were original recommendations that were not in the 2014 VA/DoD Dyslipidemia CPG?

Output: “Reviewed, New- added”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were original recommendations that were not in the 2014 VA/DoD Dyslipidemia CPG?. ### Response: “Reviewed, New- added”.


Instruction: What were recommendations carried forward from the previous version of the CPG?

Output: unchanged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were recommendations carried forward from the previous version of the CPG?. ### Response: unchanged.


Instruction: How were recommendations modified to align with the updated review of evidence?

Output: “Reviewed, New -replaced

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were recommendations modified to align with the updated review of evidence?. ### Response: “Reviewed, New -replaced.


Instruction: What was carried forward from the previous version of the CPG unchanged?

Output: Recommendations categorized as “Reviewed, Not changed”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was carried forward from the previous version of the CPG unchanged?. ### Response: Recommendations categorized as “Reviewed, Not changed”.


Instruction: What were recommendations carried forward to the updated CPG with a review of the evidence?

Output: Amended

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were recommendations carried forward to the updated CPG with a review of the evidence?. ### Response: Amended.


Instruction: What is the risk of embolic stroke in patients with anterior MI and left ventricular thrombus?

Output: increased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of embolic stroke in patients with anterior MI and left ventricular thrombus?. ### Response: increased.


Instruction: What affects 6% to 15% of patients with anterior MI?

Output: left ventric-ular thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What affects 6% to 15% of patients with anterior MI?. ### Response: left ventric-ular thrombus.


Instruction: What is the name of the article that was downloaded from http://ahajournals.org on April 28, 2023?

Output: gestive heart failure. Importantly, the risk of embolic stroke is increased in patients with anterior MI and left ventricular thrombus. Contemporary studies have found that left ventric-ular thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the article that was downloaded from http://ahajournals.org on April 28, 2023?. ### Response: gestive heart failure. Importantly, the risk of embolic stroke is increased in patients with anterior MI and left ventricular thrombus. Contemporary studies have found that left ventric-ular thrombus.


Instruction: How many RCTs examined the effect of ACEI CCBversus CCB in patients with CKD without DM?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs examined the effect of ACEI CCBversus CCB in patients with CKD without DM?. ### Response: 25.


Instruction: What is Supplementary Table 25?

Output: RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Supplementary Table 25?. ### Response: RCTs.


Instruction: RCTs examining the effect of ACE CCBversus CCB in patients with CKD without DM?

Output: þCCBversus ACEI in patients with CKD without DM [continuous outcomes].Supplementary Table 26 . RCTs examining the effect of ACEI þCCBversus CCB in patients with CKD without DM [categorical outcomes].Supplementary Table 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: RCTs examining the effect of ACE CCBversus CCB in patients with CKD without DM?. ### Response: þCCBversus ACEI in patients with CKD without DM [continuous outcomes].Supplementary Table 26 . RCTs examining the effect of ACEI þCCBversus CCB in patients with CKD without DM [categorical outcomes].Supplementary Table 27.


Instruction: How many RCTs examined the effect of b-blockerversus CCB in patients with CKD without DM?

Output: Supplementary Table 31

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs examined the effect of b-blockerversus CCB in patients with CKD without DM?. ### Response: Supplementary Table 31.


Instruction: b-blockerversus CCB in patients with CKD without DM [continuous outcomes]?

Output: central-actingagent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: b-blockerversus CCB in patients with CKD without DM [continuous outcomes]?. ### Response: central-actingagent.


Instruction: RCTs examining the effect of central-actingagent versus what?

Output: CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: RCTs examining the effect of central-actingagent versus what?. ### Response: CCB.


Instruction: What is the general population comparing ACEI diuretic versus placebo?

Output: RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the general population comparing ACEI diuretic versus placebo?. ### Response: RCTs.


Instruction: CKD with DM subgroups [categoricaloutcomes]?

Output: ACEI þdiuretic versus placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CKD with DM subgroups [categoricaloutcomes]?. ### Response: ACEI þdiuretic versus placebo.


Instruction: General population RCTs comparing ACEIdiuretic versus placebo in what group?

Output: CKD with DM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: General population RCTs comparing ACEIdiuretic versus placebo in what group?. ### Response: CKD with DM.


Instruction: How many general population RCTs comparing CCBversus active control in CKD subgroups with and without DM?

Output: 36

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many general population RCTs comparing CCBversus active control in CKD subgroups with and without DM?. ### Response: 36.


Instruction: How many Kidney International Supplements (2012) 2, 357–362chapter 3?

Output: 362

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Kidney International Supplements (2012) 2, 357–362chapter 3?. ### Response: 362.


Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e101 S10.1-7?

Output: Whelton et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e101 S10.1-7?. ### Response: Whelton et al.


Instruction: What is a prevalence of hypertension, awareness, treatment and control in the Hispanic Community Health Study/Study of Latinos?

Output: Prevalence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prevalence of hypertension, awareness, treatment and control in the Hispanic Community Health Study/Study of Latinos?. ### Response: Prevalence.


Instruction: What is APOL1 risk variants, race, and progression of chronic kidney disease?

Output: eGFR decline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is APOL1 risk variants, race, and progression of chronic kidney disease?. ### Response: eGFR decline.


Instruction: What is the status of cardio-vascular disease and stroke in Hispanics/Latinos in the United States?

Output: a science advisory from the American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the status of cardio-vascular disease and stroke in Hispanics/Latinos in the United States?. ### Response: a science advisory from the American Heart Association.


Instruction: What gene variants associate with hypertension-attributed nephropa-thy and the rate of kidney function decline in African Americans?

Output: Apolipoprotein L1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What gene variants associate with hypertension-attributed nephropa-thy and the rate of kidney function decline in African Americans?. ### Response: Apolipoprotein L1.


Instruction: What gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial?

Output: Apolipoprotein L1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial?. ### Response: Apolipoprotein L1.


Instruction: In what year did Kidney Int. 2013:83:114–20?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Kidney Int. 2013:83:114–20?. ### Response: 2013.


Instruction: What is the race, APOL1 gene variant?

Output: chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the race, APOL1 gene variant?. ### Response: chronic kidney disease.


Instruction: What does race, APOL1 risk, and eGFR decline in the general population do?

Output: Grams ME, Rebholz CM, Chen Y , et al. Race, APOL1 risk, and eGFR decline in the general population. J Am Soc Nephrol. 2016;27:2842–50.10.1.1. Racial and Ethnic Differences in Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does race, APOL1 risk, and eGFR decline in the general population do?. ### Response: Grams ME, Rebholz CM, Chen Y , et al. Race, APOL1 risk, and eGFR decline in the general population. J Am Soc Nephrol. 2016;27:2842–50.10.1.1. Racial and Ethnic Differences in Treatment.


Instruction: What is the J Am Soc Nephrol. 2016;27:2842–50.10.1.1?

Output: Racial and Ethnic Differences in Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Soc Nephrol. 2016;27:2842–50.10.1.1?. ### Response: Racial and Ethnic Differences in Treatment.


Instruction: How are high-risk hypertensive patients randomly assigned to calcium channel blocker?

Output: Clinical events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are high-risk hypertensive patients randomly assigned to calcium channel blocker?. ### Response: Clinical events.


Instruction: How were high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor?

Output: Clinical events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor?. ### Response: Clinical events.


Instruction: What did the trial to prevent heart attack do?

Output: Major outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the trial to prevent heart attack do?. ### Response: Major outcomes.


Instruction: How were ALLHAT find-ings revisited?

Output: in the context of subsequent analyses, other trials, and meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were ALLHAT find-ings revisited?. ### Response: in the context of subsequent analyses, other trials, and meta-analyses.


Instruction: What is the name of the drug that is used to treat hypertensive black and nonblack patients?

Output: chlorthalidone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat hypertensive black and nonblack patients?. ### Response: chlorthalidone.


Instruction: What are the names of the drugs that are used in the treatment of hypertension?

Output: chlorthalidone, amlodip-ine, and lisinopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the drugs that are used in the treatment of hypertension?. ### Response: chlorthalidone, amlodip-ine, and lisinopril.


Instruction: How many people were treated with chlorthalidone, amlodipine, and lisinopril?

Output: black and nonblack patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were treated with chlorthalidone, amlodipine, and lisinopril?. ### Response: black and nonblack patients.


Instruction: What is the acronym for the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?

Output: ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?. ### Response: ALLHAT.


Instruction: Who is the ALLHAT Officers and Coordinators for?

Output: ALLHAT Collaborative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the ALLHAT Officers and Coordinators for?. ### Response: ALLHAT Collaborative Research Group.


Instruction: Who is the Coordinator for the ALLHAT Collaborative Research Group?

Output: ALLHAT Officers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Coordinator for the ALLHAT Collaborative Research Group?. ### Response: ALLHAT Officers.


Instruction: What is the name of the research group that conducted a randomized trial of intensive versus standard blood pressure control?

Output: SPRINT Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the research group that conducted a randomized trial of intensive versus standard blood pressure control?. ### Response: SPRINT Research Group.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 125 of 127 112.

Output: Page 125 of 127 112.  Silverman MG, Ference BA, Im K, et al. Association between lowering LDL -C an d cardiovascular risk reduction among different therapeutic interventions: A systematic review and meta -analysis. JAMA. Sep 27 2016;  316(12):1289 -1297. PMID: 27673306.  113

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 125 of 127 112.. ### Response: Page 125 of 127 112.  Silverman MG, Ference BA, Im K, et al. Association between lowering LDL -C an d cardiovascular risk reduction among different therapeutic interventions: A systematic review and meta -analysis. JAMA. Sep 27 2016;  316(12):1289 -1297. PMID: 27673306.  113.


Instruction: What does lowering LDL -C and cardiovascular risk reduction among different therapeutic interventions do?

Output: reduce primary medication nonadherence to cardiovascular medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lowering LDL -C and cardiovascular risk reduction among different therapeutic interventions do?. ### Response: reduce primary medication nonadherence to cardiovascular medications.


Instruction: What does lower intensified target LDL -c level of statin therapy result in?

Output: higher risk of incident diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lower intensified target LDL -c level of statin therapy result in?. ### Response: higher risk of incident diabetes.


Instruction: What is a higher risk of incident diabetes?

Output: Lower intensified target LDL -c level of statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a higher risk of incident diabetes?. ### Response: Lower intensified target LDL -c level of statin therapy.


Instruction: What does a higher risk of incident diabetes result in?

Output: Lower intensified target LDL -c level of statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a higher risk of incident diabetes result in?. ### Response: Lower intensified target LDL -c level of statin therapy.


Instruction: What is the PMID for this meta -analysis?

Output: 25122464

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for this meta -analysis?. ### Response: 25122464.


Instruction: When did a cohort study of patients discontinue statins?

Output: Apr 2 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did a cohort study of patients discontinue statins?. ### Response: Apr 2 2013.


Instruction: What is the name of the study that looked at statin prescriptions after adverse reactions and patient outcomes?

Output: A cohort study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that looked at statin prescriptions after adverse reactions and patient outcomes?. ### Response: A cohort study.


Instruction: What was the PMID of Zhang H, Plutzky J, Shubina M, Turchin A?

Output: 28779871

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID of Zhang H, Plutzky J, Shubina M, Turchin A?. ### Response: 28779871.


Instruction: What did the Cleveland Clinic experience with statin intolerance do?

Output: Treatment strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Cleveland Clinic experience with statin intolerance do?. ### Response: Treatment strategies.


Instruction: What was the PMID for the study?

Output: 28779871

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID for the study?. ### Response: 28779871.


Instruction: How did the study compare to placebo controlled trials?

Output: Meta- analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the study compare to placebo controlled trials?. ### Response: Meta- analysis.


Instruction: What is the prevalence of statin intolerance?

Output: myalgia, myositis, myopathy, or myonecrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of statin intolerance?. ### Response: myalgia, myositis, myopathy, or myonecrosis.


Instruction: What was the PMID of Law M, Rudnicka AR?

Output: 28779871

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID of Law M, Rudnicka AR?. ### Response: 28779871.


Instruction: When was the Am J Cardiol. Apr 17 2006;97(8A):52C -60C?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol. Apr 17 2006;97(8A):52C -60C?. ### Response: 2006.


Instruction: What is the name of the drug used to treat veterans with statin-induced myopathy after vitamin D replenishment?

Output: statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat veterans with statin-induced myopathy after vitamin D replenishment?. ### Response: statin therapy.


Instruction: What was the PMID for this study?

Output: 28738423

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID for this study?. ### Response: 28738423.


Instruction: How many days did it take for veterans to receive vitamin D?

Output: 120

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days did it take for veterans to receive vitamin D?. ### Response: 120.


Instruction: What can be safely resolved by vitamin d supplementation?

Output: Statin intolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be safely resolved by vitamin d supplementation?. ### Response: Statin intolerance.


Instruction: What can statin intolerance due to myalgia, myositis, myopathy, or myonecrosis be resolved by?

Output: vitamin d supplementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can statin intolerance due to myalgia, myositis, myopathy, or myonecrosis be resolved by?. ### Response: vitamin d supplementation.


Instruction: What is the PMID for Cochrane corner: Interventions to improve adherence to lipid lowering medication?

Output: 29440453

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for Cochrane corner: Interventions to improve adherence to lipid lowering medication?. ### Response: 29440453.


Instruction: What does Pharmacy-based interventions reduce?

Output: primary medication nonadherence to cardiovascular medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Pharmacy-based interventions reduce?. ### Response: primary medication nonadherence to cardiovascular medications.


Instruction: What is the PMID for Med Care?

Output: 25322157

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for Med Care?. ### Response: 25322157.


Instruction: How does information technology help improve adherence?

Output: Improving adherence to cardiovascular disease medicat ions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does information technology help improve adherence?. ### Response: Improving adherence to cardiovascular disease medicat ions.


Instruction: What does information technology help with?

Output: Improving adherence to cardiovascular disease medicat ions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does information technology help with?. ### Response: Improving adherence to cardiovascular disease medicat ions.


Instruction: What is the PMID of the National Center for Health Statistics?

Output: 28779871

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID of the National Center for Health Statistics?. ### Response: 28779871.


Instruction: Where is Hyattsville, MD: Centers for Disease Control?

Output: Hyattsville

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Hyattsville, MD: Centers for Disease Control?. ### Response: Hyattsville.


Instruction: Where is the Centers for Disease Control and Prevention located?

Output: Hyattsville, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Centers for Disease Control and Prevention located?. ### Response: Hyattsville, MD.


Instruction: What should be avoided because of the shortened diastolic LV filling time across the stenotic mitral valve?

Output: Tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be avoided because of the shortened diastolic LV filling time across the stenotic mitral valve?. ### Response: Tachycardia.


Instruction: What causes an increase in LA pressure?

Output: Tachycardia should be avoided because of the shortened diastolic LV filling time across the stenotic mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes an increase in LA pressure?. ### Response: Tachycardia should be avoided because of the shortened diastolic LV filling time across the stenotic mitral valve.


Instruction: What is the risk of elective noncardiac surgery in asymptomatic patients with significant rheumatic MS?

Output: considerably higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of elective noncardiac surgery in asymptomatic patients with significant rheumatic MS?. ### Response: considerably higher.


Instruction: What should be evaluated and treated as outlined in the rheumatic MS section?

Output: stolic pressure >50 mm Hg, the risk of elective inter -mediate- to high-risk noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be evaluated and treated as outlined in the rheumatic MS section?. ### Response: stolic pressure >50 mm Hg, the risk of elective inter -mediate- to high-risk noncardiac surgery.


Instruction: What are the overall hemodynamic goals in asymptomatic patients?

Output: avoidance of both increased afterload and bradycardia by choosing the appropriate anesthetic scheme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the overall hemodynamic goals in asymptomatic patients?. ### Response: avoidance of both increased afterload and bradycardia by choosing the appropriate anesthetic scheme.


Instruction: What are the hemodynamic goals of elective noncardiac surgery?

Output: avoidance of both increased afterload and bradycardia by choosing the appropriate anesthetic scheme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the hemodynamic goals of elective noncardiac surgery?. ### Response: avoidance of both increased afterload and bradycardia by choosing the appropriate anesthetic scheme.


Instruction: What are left-sided regurgitant lesions better tolerated than?

Output: stenotic valvular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are left-sided regurgitant lesions better tolerated than?. ### Response: stenotic valvular disease.


Instruction: What is stenotic valvular disease?

Output: Left-sided regurgitant lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stenotic valvular disease?. ### Response: Left-sided regurgitant lesions.


Instruction: Patients with significant MR undergoing noncardiac surgery had higher rates of postoperative HF and myocardial infarction than did controls without MR?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with significant MR undergoing noncardiac surgery had higher rates of postoperative HF and myocardial infarction than did controls without MR?. ### Response: 11.


Instruction: What combination of neuraxial local anesthetics and opioids produces a favor able systemic vasodilation for patients with regurgitant valve lesions?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What combination of neuraxial local anesthetics and opioids produces a favor able systemic vasodilation for patients with regurgitant valve lesions?. ### Response: 4.


Instruction: What does general anesthesia lower systemic vas-cular resistance?

Output: Patients with regur -gitant lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does general anesthesia lower systemic vas-cular resistance?. ### Response: Patients with regur -gitant lesions.


Instruction: What should be maintained for patients with regurgitant valve lesions?

Output: preload

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be maintained for patients with regurgitant valve lesions?. ### Response: preload.


Instruction: Invasive hemodynamic and/or intraoperative TEE monitoring allows for what?

Output: continuous optimization of LV filling pressures and LV function during and after the opera-tive procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Invasive hemodynamic and/or intraoperative TEE monitoring allows for what?. ### Response: continuous optimization of LV filling pressures and LV function during and after the opera-tive procedure.


Instruction: What should patients be admitted to an intensive monitoring setting for up to 24 to 72 hours after the procedure?

Output: Invasive hemodynamic and/or intraoperative TEE monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients be admitted to an intensive monitoring setting for up to 24 to 72 hours after the procedure?. ### Response: Invasive hemodynamic and/or intraoperative TEE monitoring.


Instruction: In functional MR, attention to afterload control and fluid balance should be given what?

Output: careful

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In functional MR, attention to afterload control and fluid balance should be given what?. ### Response: careful.


Instruction: What is a common cause of hemody-namic instability in patients with severe AR?

Output: increased volume on myocardial wall stress

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of hemody-namic instability in patients with severe AR?. ### Response: increased volume on myocardial wall stress.


Instruction: What is another term for ischemic heart disease and hypertrophic cardiomyopathy?

Output: under -lying heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for ischemic heart disease and hypertrophic cardiomyopathy?. ### Response: under -lying heart disease.


Instruction: What may the perioperative stress associated with noncardiac surgery lead to?

Output: hypotension, arrhythmias, HF, or even death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may the perioperative stress associated with noncardiac surgery lead to?. ### Response: hypotension, arrhythmias, HF, or even death.


Instruction: Patients with sig-nificant AR had a higher in-hospital mortality rate and higher mor-bidity rate?

Output: noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with sig-nificant AR had a higher in-hospital mortality rate and higher mor-bidity rate?. ### Response: noncardiac surgery.