Instruction: What is a potential for other agents to cross the placenta?

Output: Cost, coverage, licensing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential for other agents to cross the placenta?. ### Response: Cost, coverage, licensing.


Instruction: What is the abbreviation for Evidence-Based Medicine?

Output: 326

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the abbreviation for Evidence-Based Medicine?. ### Response: 326.


Instruction: How was the 2013 AIS Guidelines revised?

Output: to match COR III stratifications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the 2013 AIS Guidelines revised?. ### Response: to match COR III stratifications.


Instruction: What was the 2015 Recommendation Classification System?

Output: ACC/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2015 Recommendation Classification System?. ### Response: ACC/AHA.


Instruction: Where should rehabilitation be provided for hospitalized stroke patients?

Output: environments with organized, interprofessional stroke care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where should rehabilitation be provided for hospitalized stroke patients?. ### Response: environments with organized, interprofessional stroke care.


Instruction: Where should rehabilitation for hospitalized stroke patients be provided?

Output: in environments with organized, interprofessional stroke care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where should rehabilitation for hospitalized stroke patients be provided?. ### Response: in environments with organized, interprofessional stroke care.


Instruction: What is recommended that stroke survivors receive rehabilitation at an intensity commensurate with anticipated benefit and tolerance?

Output: B-NRRecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended that stroke survivors receive rehabilitation at an intensity commensurate with anticipated benefit and tolerance?. ### Response: B-NRRecommendation.


Instruction: What was COR unchanged from?

Output: 2016 Rehab Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was COR unchanged from?. ### Response: 2016 Rehab Guidelines.


Instruction: What was LOE amended to conform with?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was LOE amended to conform with?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: How should all individuals with stroke be assessed?

Output: formal assessment of their activities of daily living and instrumental activities of daily living, communication abilities, and functional mobility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should all individuals with stroke be assessed?. ### Response: formal assessment of their activities of daily living and instrumental activities of daily living, communication abilities, and functional mobility.


Instruction: What should findings be incorporated into the care transition and discharge planning process?

Output: It is recommended that all individuals with stroke be provided a formal assessment of their activities of daily living and instrumental activities of daily living, communication abilities, and functional mobility before discharge from acute care hospitalization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should findings be incorporated into the care transition and discharge planning process?. ### Response: It is recommended that all individuals with stroke be provided a formal assessment of their activities of daily living and instrumental activities of daily living, communication abilities, and functional mobility before discharge from acute care hospitalization.


Instruction: What is unchanged from 2016 Rehab Guidelines?

Output: ARecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unchanged from 2016 Rehab Guidelines?. ### Response: ARecommendation.


Instruction: How was LOE amended to conform with ACC/AHA 2015 Recommendation Classification System?

Output: I C-LDRecommendation and COR unchanged from 2016 Rehab Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was LOE amended to conform with ACC/AHA 2015 Recommendation Classification System?. ### Response: I C-LDRecommendation and COR unchanged from 2016 Rehab Guidelines.


Instruction: What is recommended for patients with an acute stroke with residual functional deficits?

Output: A functional assessment by a clinician with expertise in rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with an acute stroke with residual functional deficits?. ### Response: A functional assessment by a clinician with expertise in rehabilitation.


Instruction: What is the C-LDRecommendation and COR unchanged from 2016 Rehab Guidelines?

Output: IIb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the C-LDRecommendation and COR unchanged from 2016 Rehab Guidelines?. ### Response: IIb.


Instruction: LOE amended to conform with what?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LOE amended to conform with what?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: What does ACC/AHA 2015 Recommendation Classification System conform to?

Output: 2016 Rehab Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACC/AHA 2015 Recommendation Classification System conform to?. ### Response: 2016 Rehab Guidelines.


Instruction: What is the effectiveness of fluoxetine or other selective serotonin reuptake inhibitors to enhance motor recovery not well established?

Output: The effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effectiveness of fluoxetine or other selective serotonin reuptake inhibitors to enhance motor recovery not well established?. ### Response: The effectiveness.


Instruction: What vitamin K antagonist was used to treat graft occlusion?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What vitamin K antagonist was used to treat graft occlusion?. ### Response: warfarin.


Instruction: In what year did Pantely and colleagues find no improvement in grafting patency?

Output: 1979

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Pantely and colleagues find no improvement in grafting patency?. ### Response: 1979.


Instruction: What was the name of one of the first trials on the topic of anticoagulation with warfarin?

Output: Pantely et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of one of the first trials on the topic of anticoagulation with warfarin?. ### Response: Pantely et al.


Instruction: What was the name of the largest trial in the field?

Output: Post-Coronary Artery Bypass Graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the largest trial in the field?. ### Response: Post-Coronary Artery Bypass Graft.


Instruction: How many patients were in the Post-CABG trial?

Output: 1351

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were in the Post-CABG trial?. ### Response: 1351.


Instruction: What is another name for Artery Bypass Graft?

Output: Post-CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Artery Bypass Graft?. ### Response: Post-CABG.


Instruction: What was the mean international normalized ratio of warfarin anticoagulation?

Output: 1.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean international normalized ratio of warfarin anticoagulation?. ### Response: 1.4.


Instruction: Who noted no significant differences in angiographic outcome between the patients who were randomized?

Output: The authors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who noted no significant differences in angiographic outcome between the patients who were randomized?. ### Response: The authors.


Instruction: What drug did not slow the process of vein graft disease?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug did not slow the process of vein graft disease?. ### Response: warfarin.


Instruction: What did Fremes et al summarize the literature with?

Output: a meta-analysis of 17 tri-als on antithrombotic and antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Fremes et al summarize the literature with?. ### Response: a meta-analysis of 17 tri-als on antithrombotic and antiplatelet therapy.


Instruction: How many tri-als were on antithrombotic and antiplatelet therapy after CABG?

Output: 17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many tri-als were on antithrombotic and antiplatelet therapy after CABG?. ### Response: 17.


Instruction: How many trials were on antithrombotic and antiplatelet therapy after CABG?

Output: 17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many trials were on antithrombotic and antiplatelet therapy after CABG?. ### Response: 17.


Instruction: What did aspirin and anticoagulation reduce the odds of?

Output: bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did aspirin and anticoagulation reduce the odds of?. ### Response: bleeding complications.


Instruction: Anticoagulation did not improve graft patency compared with what?

Output: aspirin alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anticoagulation did not improve graft patency compared with what?. ### Response: aspirin alone.


Instruction: What did not improve graft patency compared with aspirin alone?

Output: anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not improve graft patency compared with aspirin alone?. ### Response: anticoagulation.


Instruction: What does the data do not support the use of?

Output: warfarin anti-thrombotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the data do not support the use of?. ### Response: warfarin anti-thrombotic therapy.


Instruction: What should be reserved for patients recovering from CABG who have other indications for warfarin?

Output: postopera-tive antithrombotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be reserved for patients recovering from CABG who have other indications for warfarin?. ### Response: postopera-tive antithrombotic therapy.


Instruction: Patients with a history of venous thromboembolism should continue to receive what?

Output: aspirin 81 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with a history of venous thromboembolism should continue to receive what?. ### Response: aspirin 81 mg daily.


Instruction: What is the lowest dose of aspirin given after CABG?

Output: 75–162 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the lowest dose of aspirin given after CABG?. ### Response: 75–162 mg daily.


Instruction: What are some newer antithrombotic agents?

Output: dabigatran, apixaban, rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some newer antithrombotic agents?. ### Response: dabigatran, apixaban, rivaroxaban.


Instruction: What are some of the newer antithrombotic agents?

Output: dabigatran, apixaban, rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the newer antithrombotic agents?. ### Response: dabigatran, apixaban, rivaroxaban.


Instruction: What has been raised about their use early after surgery and in those with mechanical prosthetic valves?

Output: safety concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been raised about their use early after surgery and in those with mechanical prosthetic valves?. ### Response: safety concerns.


Instruction: Warfarin should not be routinely prescribed what?

Output: Antithrombotic Therapy Recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Warfarin should not be routinely prescribed what?. ### Response: Antithrombotic Therapy Recommendations.


Instruction: What should not be routinely prescribed after CABG for graft patency?

Output: Warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be routinely prescribed after CABG for graft patency?. ### Response: Warfarin.


Instruction: What should patients have other indications for long-term antithrombotic therapy?

Output: antiplatelet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients have other indications for long-term antithrombotic therapy?. ### Response: antiplatelet.


Instruction: Antithrombotic alternatives to warfarin (dabiga-tran, apixaban, rivaroxaban) should not be routinely used?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antithrombotic alternatives to warfarin (dabiga-tran, apixaban, rivaroxaban) should not be routinely used?. ### Response: 2.


Instruction: What are the normalized ratios for lupus anticoagulant screen?

Output: s/c, normalized ratios for lupus anticoagulant screen and lupus anticoagulant–confirm coagulation times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the normalized ratios for lupus anticoagulant screen?. ### Response: s/c, normalized ratios for lupus anticoagulant screen and lupus anticoagulant–confirm coagulation times.


Instruction: What is the von Willebrand factor?

Output: vWF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the von Willebrand factor?. ### Response: vWF.


Instruction: What is the name of the website that contains the information on diabetes mellitus?

Output: ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the website that contains the information on diabetes mellitus?. ### Response: ahajournals.org.


Instruction: When was this information released?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this information released?. ### Response: April 28, 2023.


Instruction: Where was it downloaded?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was it downloaded?. ### Response: http://ahajournals.org.


Instruction: What type of patients have a lower risk of VA and SCD compared to those with prolonged QTc?

Output: Patients with long QT  syndrome and normal QTc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients have a lower risk of VA and SCD compared to those with prolonged QTc?. ### Response: Patients with long QT  syndrome and normal QTc.


Instruction: Patients with long QT syndrome have an increased risk of SCA or what?

Output: SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with long QT syndrome have an increased risk of SCA or what?. ### Response: SCD.


Instruction: Beta blockers reduce the risk of what types of patients?

Output: Asymptomatic adult (male) long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beta blockers reduce the risk of what types of patients?. ### Response: Asymptomatic adult (male) long QT syndrome.


Instruction: What does beta blockers reduce the risk of?

Output: adverse cardiac events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does beta blockers reduce the risk of?. ### Response: adverse cardiac events.


Instruction: What are the periods of highest risk in the first 3 decades of life?

Output: S7.9.1.1-11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the periods of highest risk in the first 3 decades of life?. ### Response: S7.9.1.1-11.


Instruction: When do changes in QTc occur?

Output: over time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When do changes in QTc occur?. ### Response: over time.


Instruction: What happens over time during puberty and after pregnancies?

Output: Changes in QTc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What happens over time during puberty and after pregnancies?. ### Response: Changes in QTc.


Instruction: What should be assessed on ECG annually or with medication changes?

Output: QTc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be assessed on ECG annually or with medication changes?. ### Response: QTc.


Instruction: How should we assess medication efficacy?

Output: exercise testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should we assess medication efficacy?. ### Response: exercise testing.


Instruction: What may adult male long QT syndrome patients choose to decline?

Output: beta-blocker therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may adult male long QT syndrome patients choose to decline?. ### Response: beta-blocker therapy.


Instruction: What is influenced by the patient's resting QTc inter-val, age, sex, and longQT syndrome genotype/mutation?

Output: The risk of adverse cardiac events from VA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is influenced by the patient's resting QTc inter-val, age, sex, and longQT syndrome genotype/mutation?. ### Response: The risk of adverse cardiac events from VA.


Instruction: When is the risk of cardiac events highest for asymptomatic males with long QT syndrome?

Output: childhood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the risk of cardiac events highest for asymptomatic males with long QT syndrome?. ### Response: childhood.


Instruction: What is at risk for young women with LQT2 and QTc >500 ms?

Output: increased risk of SCAS7.9.1.1-2,S7.9.1.1-11,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is at risk for young women with LQT2 and QTc >500 ms?. ### Response: increased risk of SCAS7.9.1.1-2,S7.9.1.1-11,.


Instruction: What may be candidates for primary prevention ICD placement or use of a wearable cardioverter-defibrillator?

Output: Young women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be candidates for primary prevention ICD placement or use of a wearable cardioverter-defibrillator?. ### Response: Young women.


Instruction: What increases the risk of adverse events in patients with long QT syndrome?

Output: Concurrent use of stimulant or nonstimu-lant attention deficit/hyperactivity medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the risk of adverse events in patients with long QT syndrome?. ### Response: Concurrent use of stimulant or nonstimu-lant attention deficit/hyperactivity medications.


Instruction: What should not be used in patients with long QT syndrome unless there is no suitable alternative?

Output: S7.9.1.1-59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be used in patients with long QT syndrome unless there is no suitable alternative?. ### Response: S7.9.1.1-59.


Instruction: What is recommended for careful monitoring of the QTc during therapy?

Output: ECG annually or with medication changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for careful monitoring of the QTc during therapy?. ### Response: ECG annually or with medication changes.


Instruction: What was associated with an increased risk of syncope/cardiac arrest in long QT syndrome?

Output: Concurrent use of stimulant or nonstimu-lant attention deficit/hyperactivity medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with an increased risk of syncope/cardiac arrest in long QT syndrome?. ### Response: Concurrent use of stimulant or nonstimu-lant attention deficit/hyperactivity medications.


Instruction: What did not appear to be associated with increased risk in another ret-rospective study?

Output: S7.9.1.1-34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not appear to be associated with increased risk in another ret-rospective study?. ### Response: S7.9.1.1-34.


Instruction: What can precipitate episodes of torsades de pointes?

Output: exposure to a QT prolonging medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can precipitate episodes of torsades de pointes?. ### Response: exposure to a QT prolonging medication.


Instruction: What can be precipitated by exposure to a QT prolonging medication?

Output: Episodes of torsades de pointes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be precipitated by exposure to a QT prolonging medication?. ### Response: Episodes of torsades de pointes.


Instruction: Attention to maintaining normal potassium and magne-sium balance when medications or situations?

Output: medication compliance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Attention to maintaining normal potassium and magne-sium balance when medications or situations?. ### Response: medication compliance.


Instruction: What is the 95% CI of the higher dose of dihydropyridine CCB?

Output: 2.79 higher –7.74 higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% CI of the higher dose of dihydropyridine CCB?. ### Response: 2.79 higher –7.74 higher.


Instruction: What was the mean follow-up of pla-cebo over a mean of 15.3 months?

Output: SupplementaryTable S33314,317,318,321,322,330–334

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean follow-up of pla-cebo over a mean of 15.3 months?. ### Response: SupplementaryTable S33314,317,318,321,322,330–334.


Instruction: The tradeoffs with these interventions include what?

Output: greater fragility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The tradeoffs with these interventions include what?. ### Response: greater fragility.


Instruction: Inkidney function, hyperkalemia336) What did the evidence review find about ACEi, alpha-blocker, beta-blockers, andMRAs?

Output: had no signi ﬁcant effect on mortality, graft loss,or CV events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inkidney function, hyperkalemia336) What did the evidence review find about ACEi, alpha-blocker, beta-blockers, andMRAs?. ### Response: had no signi ﬁcant effect on mortality, graft loss,or CV events.


Instruction: What was found to have no effect on mortality, graft loss, or CV events?

Output: blockers, beta-blockers, andMRAs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to have no effect on mortality, graft loss, or CV events?. ### Response: blockers, beta-blockers, andMRAs.


Instruction: What was shown to be effective at reducing BP and proteinuria in kidney transplant recipients?

Output: ACEi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was shown to be effective at reducing BP and proteinuria in kidney transplant recipients?. ### Response: ACEi.


Instruction: There was no signi fi-cant effect of ACEi on all-cause mortality or graft loss, and their use was associated with what?

Output: CV events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There was no signi fi-cant effect of ACEi on all-cause mortality or graft loss, and their use was associated with what?. ### Response: CV events.


Instruction: What was associated with a signi ficant increase in adverse events in the kidney transplant population?

Output: ACEi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a signi ficant increase in adverse events in the kidney transplant population?. ### Response: ACEi.


Instruction: What did the ERT update a Cochrane sys-tematic review296?

Output: Quality of evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ERT update a Cochrane sys-tematic review296?. ### Response: Quality of evidence.


Instruction: What is a serious risk of bias?

Output: unclear randomization sequencegeneration and allocation concealment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a serious risk of bias?. ### Response: unclear randomization sequencegeneration and allocation concealment.


Instruction: Why is the evidence for the use of an ARB or CCB considered low quality?

Output: a serious risk of bias (unclear randomization sequencegeneration and allocation concealment) and imprecisionaround the effect estimates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the evidence for the use of an ARB or CCB considered low quality?. ### Response: a serious risk of bias (unclear randomization sequencegeneration and allocation concealment) and imprecisionaround the effect estimates.


Instruction: How many graft failure events were there in the ARB trials?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many graft failure events were there in the ARB trials?. ### Response: 25.


Instruction: How many participants had a total of 25graft fail outcomes?

Output: 786

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants had a total of 25graft fail outcomes?. ### Response: 786.


Instruction: What do transplant recipients place a high priority on?

Output: allograft survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do transplant recipients place a high priority on?. ### Response: allograft survival.


Instruction: What does SONG-Tx stand for?

Output: KidneyTransplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SONG-Tx stand for?. ### Response: KidneyTransplantation.


Instruction: How many patients or caregivers completed a Delphi survey?

Output: 461

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients or caregivers completed a Delphi survey?. ### Response: 461.


Instruction: From how many countries did the Delphi survey come from?

Output: 79

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: From how many countries did the Delphi survey come from?. ### Response: 79.


Instruction: How many health pro-fessionals from 79 countries participated in consensusconferences?

Output: 557

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many health pro-fessionals from 79 countries participated in consensusconferences?. ### Response: 557.


Instruction: What was the primary priority for patients, caregivers, and health professionals?

Output: Kidney allograft survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary priority for patients, caregivers, and health professionals?. ### Response: Kidney allograft survival.


Instruction: How did patients feel about returning to dialysis?

Output: dread

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did patients feel about returning to dialysis?. ### Response: dread.


Instruction: What did the patients focus on?

Output: well-being

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the patients focus on?. ### Response: well-being.


Instruction: What was the top priority of the patients?

Output: allograft survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the top priority of the patients?. ### Response: allograft survival.


Instruction: Why were patients more concerned with quality of life than quantity of life?

Output: Preventing graft loss was the top priority

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were patients more concerned with quality of life than quantity of life?. ### Response: Preventing graft loss was the top priority.


Instruction: The SONG-Tx work provides strong rationale for what?

Output: the useof interventions that will reduce graft failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The SONG-Tx work provides strong rationale for what?. ### Response: the useof interventions that will reduce graft failure.


Instruction: What is the opinion of the Work Group that most well-informed transplant patients would have the same values and preferences for the avoidance of graft loss?

Output: SONG-Tx

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the opinion of the Work Group that most well-informed transplant patients would have the same values and preferences for the avoidance of graft loss?. ### Response: SONG-Tx.


Instruction: What is the benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels?

Output: Improve Long-term Outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels?. ### Response: Improve Long-term Outcome.


Instruction: What study investigators used the Fab Antiplatelet Therapy in Unstable Refractory Angina (CAPTURE) Study?

Output: pre-vent Recurrent Events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study investigators used the Fab Antiplatelet Therapy in Unstable Refractory Angina (CAPTURE) Study?. ### Response: pre-vent Recurrent Events.


Instruction: What is used in high-risk coronary angioplasty?

Output: monoclonal antibody

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used in high-risk coronary angioplasty?. ### Response: monoclonal antibody.


Instruction: What is a monoclonal antibody directed against?

Output: platelet glycopro-tein IIb/IIIa receptor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a monoclonal antibody directed against?. ### Response: platelet glycopro-tein IIb/IIIa receptor.


Instruction: In what year was tirofi-ban administered?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was tirofi-ban administered?. ### Response: 1994.


Instruction: What is the ADV ANCE Trial?

Output: The additive value of tirofi-ban administered with the high-dose bolus in the prevention of ischemic complications during high-risk coronary angioplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ADV ANCE Trial?. ### Response: The additive value of tirofi-ban administered with the high-dose bolus in the prevention of ischemic complications during high-risk coronary angioplasty.


Instruction: What is ESPRIT?

Output: planned coronary stent implanta-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ESPRIT?. ### Response: planned coronary stent implanta-tion.


Instruction: In what year did the Lancet issue 356: 2037-44?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the Lancet issue 356: 2037-44?. ### Response: 2000.


Instruction: What is the name of the study that evaluated the effects of aspirin and clopidogrel in patients with acute coronary syndromes?

Output: Clopidogrel in Unstable angina to pre-vent Recurrent Events (CURE) study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the effects of aspirin and clopidogrel in patients with acute coronary syndromes?. ### Response: Clopidogrel in Unstable angina to pre-vent Recurrent Events (CURE) study.


Instruction: What is CURE?

Output: pre-vent Recurrent Events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CURE?. ### Response: pre-vent Recurrent Events.


Instruction: When did Circulation issue 108:1682–7?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation issue 108:1682–7?. ### Response: 2003.


Instruction: What is the name of the CURE study?

Output: Clopidogrel in Unstable angina to pre-vent Recurrent Events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the CURE study?. ### Response: Clopidogrel in Unstable angina to pre-vent Recurrent Events.


Instruction: How many patients were enrolled in 31 randomized controlled trials?

Output: 192,036

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in 31 randomized controlled trials?. ### Response: 192,036.


Instruction: What does aspirin do to prevent cardio-vascular disease?

Output: the association of aspirin dose and clopidogrel with thrombosis and bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does aspirin do to prevent cardio-vascular disease?. ### Response: the association of aspirin dose and clopidogrel with thrombosis and bleeding.


Instruction: What does clopidogrel do to thrombosis and bleeding?

Output: aspirin dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does clopidogrel do to thrombosis and bleeding?. ### Response: aspirin dose.


Instruction: Who wrote the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)?

Output: Patrono C, Baigent C, Hirsh J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)?. ### Response: Patrono C, Baigent C, Hirsh J.


Instruction: What is the 8th edition of the College of Chest Physicians Evidence-Based Clinical Practice Guidelines?

Output: Antiplatelet drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 8th edition of the College of Chest Physicians Evidence-Based Clinical Practice Guidelines?. ### Response: Antiplatelet drugs.


Instruction: What are the results of the EPILOG and EPISTENT tri-als?

Output: Abciximab and bleeding during coronary surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the EPILOG and EPISTENT tri-als?. ### Response: Abciximab and bleeding during coronary surgery.


Instruction: What is clopidogrel used for in angina to prevent recurrent events?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel used for in angina to prevent recurrent events?. ### Response: percutaneous coronary intervention.


Instruction: What is the name of the study that evaluated platelet IIb/IIIa inhibition in STENTing?

Output: Ann Thorac Surg. 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated platelet IIb/IIIa inhibition in STENTing?. ### Response: Ann Thorac Surg. 2000.


Instruction: How many patients were treated with stan-dard-dose?

Output: 192,036

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with stan-dard-dose?. ### Response: 192,036.


Instruction: What is the name of the randomised factorial trial?

Output: CURRENT-OASIS 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised factorial trial?. ### Response: CURRENT-OASIS 7.


Instruction: What does clopidogrel do in comparison to stan-dard-dose aspirin?

Output: thrombosis and bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does clopidogrel do in comparison to stan-dard-dose aspirin?. ### Response: thrombosis and bleeding.


Instruction: In what year was the Lancet 376:1233-43 published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Lancet 376:1233-43 published?. ### Response: 2010.


Instruction: What reduces mortality in diabetic patients with non-ST-segment-elevation acute coronary syndromes?

Output: Platelet glycoprotein IIb/IIIa inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduces mortality in diabetic patients with non-ST-segment-elevation acute coronary syndromes?. ### Response: Platelet glycoprotein IIb/IIIa inhibitors.


Instruction: When did Circulation. 2001;104:2767-71?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2001;104:2767-71?. ### Response: 2002.


Instruction: What is the efficacy and safety of prasugrel with and without a glycoprotein IIb/IIIa inhibi-tion?

Output: Improve Long-term Outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the efficacy and safety of prasugrel with and without a glycoprotein IIb/IIIa inhibi-tion?. ### Response: Improve Long-term Outcome.


Instruction: What is the effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction?. ### Response: Effect.


Instruction: What are the results of the survival and ven-tricular enlargement trial?

Output: Effect of captopril on mortality and morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the survival and ven-tricular enlargement trial?. ### Response: Effect of captopril on mortality and morbidity.


Instruction: Who are the SAVE Investigators?

Output: N Engl J Med

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who are the SAVE Investigators?. ### Response: N Engl J Med.


Instruction: What is the name of the study that investigated the effects of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure?

Output: The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effects of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure?. ### Response: The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators.


Instruction: What are the names of the investigators of the Acute Infarction Ramiprill Efficacy Study?

Output: Pfeffer MA, Braunwald E, Moye LA, et al .

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the investigators of the Acute Infarction Ramiprill Efficacy Study?. ### Response: Pfeffer MA, Braunwald E, Moye LA, et al ..


Instruction: What is trandolapril angiotensin-converting-enzyme inhibitor used for in patients with left ventricular dysfunction after myocardial infarction?

Output: A clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is trandolapril angiotensin-converting-enzyme inhibitor used for in patients with left ventricular dysfunction after myocardial infarction?. ### Response: A clinical trial.


Instruction: What is the TRACE Study Group?

Output: Tran-dolapril Cardiac Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the TRACE Study Group?. ### Response: Tran-dolapril Cardiac Evaluation.


Instruction: What is the name of the angiotensin-receptor blocker used in chronic heart failure?

Output: valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the angiotensin-receptor blocker used in chronic heart failure?. ### Response: valsartan.


Instruction: When was the trial of valsartan released?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the trial of valsartan released?. ### Response: May 3, 2023.


Instruction: What is the risk of ASCVD in older adults?

Output: ≥ 10%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of ASCVD in older adults?. ### Response: ≥ 10%,.


Instruction: What is a high risk category that requires initiation of antihypertensive drug therapy at BP  130/80mm Hg?

Output: older adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a high risk category that requires initiation of antihypertensive drug therapy at BP  130/80mm Hg?. ### Response: older adults.


Instruction: What is the BP threshold for initiating antihypertensive drug therapy?

Output: BP ≥ 130/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BP threshold for initiating antihypertensive drug therapy?. ### Response: BP ≥ 130/80 mm Hg.


Instruction: When was the ahajournals published?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ahajournals published?. ### Response: May 3, 2023.


Instruction: In what year was the KDIGO Clinical Practice Guideline for theManagement of Blood Pressure in Chronic Kidney Disease (CKD) published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the KDIGO Clinical Practice Guideline for theManagement of Blood Pressure in Chronic Kidney Disease (CKD) published?. ### Response: 2012.


Instruction: In what month and year did the Controversies Conference take place?

Output: September

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what month and year did the Controversies Conference take place?. ### Response: September.


Instruction: What was the objective of the project?

Output: to update the evidence-basedclinical practice guideline for the management of BP in patientswith CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the objective of the project?. ### Response: to update the evidence-basedclinical practice guideline for the management of BP in patientswith CKD.


Instruction: What did the project aim to update?

Output: evidence-basedclinical practice guideline for the management of BP in patientswith CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the project aim to update?. ### Response: evidence-basedclinical practice guideline for the management of BP in patientswith CKD.


Instruction: How was the guideline developed?

Output: in accordancewith the AGREE II reporting checklist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the guideline developed?. ### Response: in accordancewith the AGREE II reporting checklist.


Instruction: What is the name of the guideline that adhered to international best practice for guidelinedevelopment?

Output: Appendix B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline that adhered to international best practice for guidelinedevelopment?. ### Response: Appendix B.


Instruction: How many people were involved in the development of the KDIGO 2021 Clinical PracticeGuideline for the Management of Cancer?

Output: 375,376

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were involved in the development of the KDIGO 2021 Clinical PracticeGuideline for the Management of Cancer?. ### Response: 375,376.


Instruction: What is the KDIGO 2021 Clinical PracticeGuideline for the Management of Blood Pressure in CKD?

Output: 377

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the KDIGO 2021 Clinical PracticeGuideline for the Management of Blood Pressure in CKD?. ### Response: 377.


Instruction: Who is responsible for appointing Work Group members and the ERT?

Output: KDIGO Co-Chairs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is responsible for appointing Work Group members and the ERT?. ### Response: KDIGO Co-Chairs.


Instruction: What is PICOM?

Output: Comparator, Outcome, Methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PICOM?. ### Response: Comparator, Outcome, Methods.


Instruction: What are the topics for systematic evidence review and linking to?

Output: existing Cochrane Kidney and Transplant systematic reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the topics for systematic evidence review and linking to?. ### Response: existing Cochrane Kidney and Transplant systematic reviews.


Instruction: What is the focus of the literature search strategies?

Output: Selecting studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the literature search strategies?. ### Response: Selecting studies.


Instruction: When was the public review of the guide?

Output: January 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the public review of the guide?. ### Response: January 2020.


Instruction: What process was followed in the majority of guideline chapters?

Output: development

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What process was followed in the majority of guideline chapters?. ### Response: development.


Instruction: What did the Work Group coauthors do to ensure that the draft of the chapter was accurate?

Output: additional reviews and clari ﬁcations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group coauthors do to ensure that the draft of the chapter was accurate?. ### Response: additional reviews and clari ﬁcations.


Instruction: What did Chapter 3 require?

Output: an iterative process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Chapter 3 require?. ### Response: an iterative process.


Instruction: Who was responsible for ensuring that the draft of the chapter reflected available evidence?

Output: Work Group coauthors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was responsible for ensuring that the draft of the chapter reflected available evidence?. ### Response: Work Group coauthors.


Instruction: Who appointed the Work Group Co-Chairs?

Output: The KDIGO Co-Chairs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who appointed the Work Group Co-Chairs?. ### Response: The KDIGO Co-Chairs.


Instruction: What did the Cochrane Kidney and Transplant Group include?

Output: systematic reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Cochrane Kidney and Transplant Group include?. ### Response: systematic reviews.


Instruction: What was Cochrane Kidney and Transplant contracted to conduct?

Output: systematic evidence review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was Cochrane Kidney and Transplant contracted to conduct?. ### Response: systematic evidence review.


Instruction: What did the ERT consist of?

Output: adultand pediatric nephrologists, and methodologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ERT consist of?. ### Response: adultand pediatric nephrologists, and methodologists.


Instruction: Who were the nephrologists and methodologists with expertise in?

Output: The ERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were the nephrologists and methodologists with expertise in?. ### Response: The ERT.


Instruction: When testing is used inappropriately or overused, thebenefit of testing is low and the risk of exposure is unac-ceptably high?

Output: 13,14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When testing is used inappropriately or overused, thebenefit of testing is low and the risk of exposure is unac-ceptably high?. ### Response: 13,14.


Instruction: What should be taken when exposing low-risk patients to ionizing radiation?

Output: care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be taken when exposing low-risk patients to ionizing radiation?. ### Response: care.


Instruction: What is particularly of concern in younger patients for whom the projected cancerrisk is elevated?

Output: ionizing radiation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is particularly of concern in younger patients for whom the projected cancerrisk is elevated?. ### Response: ionizing radiation.


Instruction: Use of contrast agents with CCTA can cause allergic reactions?

Output: 102

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Use of contrast agents with CCTA can cause allergic reactions?. ### Response: 102.


Instruction: Contrast agents also can affect what?

Output: renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Contrast agents also can affect what?. ### Response: renal function.


Instruction: What is CMR contraindicated in patients withclaustrophobia or implanted devices?

Output: gadolinium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CMR contraindicated in patients withclaustrophobia or implanted devices?. ### Response: gadolinium.


Instruction: What is rarely associated with nephrogenic systemicfibrosis?

Output: use of gadoliniumcontrast agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rarely associated with nephrogenic systemicfibrosis?. ### Response: use of gadoliniumcontrast agents.


Instruction: Inpatients with severe renal dysfunction should gadolinium be avoided?

Output: gadolinium is contraindicated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inpatients with severe renal dysfunction should gadolinium be avoided?. ### Response: gadolinium is contraindicated.


Instruction: What are the estimated glomerularfiltration rates per 1.73 mL?

Output: 30 to 60 mL/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the estimated glomerularfiltration rates per 1.73 mL?. ### Response: 30 to 60 mL/min.


Instruction: What is the recommended dose for patients with mild to moderate dysfunction?

Output: 30 to 60 mL/min per1.73 m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended dose for patients with mild to moderate dysfunction?. ### Response: 30 to 60 mL/min per1.73 m2.


Instruction: In addition to pretest likelihood, a variety of what factors influence noninvasive test selection?

Output: clinical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to pretest likelihood, a variety of what factors influence noninvasive test selection?. ### Response: clinical.


Instruction: What are some of the most important factors in noninvasive testing?

Output: the patient’s ability to exercise, body habitus, cardiacmedication use, and ECG interpretability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the most important factors in noninvasive testing?. ### Response: the patient’s ability to exercise, body habitus, cardiacmedication use, and ECG interpretability.


Instruction: The patient's ability to exercise, body habitus, cardiacmedication use, and ECG interpretability are examples of what?

Output: clinical factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The patient's ability to exercise, body habitus, cardiacmedication use, and ECG interpretability are examples of what?. ### Response: clinical factors.


Instruction: What is important in patients who have an interpretable ECG and arecapable of vigorous exercise?

Output: addimaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important in patients who have an interpretable ECG and arecapable of vigorous exercise?. ### Response: addimaging.


Instruction: What have different diagnostic accuracies,predictive values, and costs?

Output: imagingand nonimaging testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have different diagnostic accuracies,predictive values, and costs?. ### Response: imagingand nonimaging testing.


Instruction: Most studies evaluate cohorts of patients undergoing exercise ECGand what else?

Output: stress imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most studies evaluate cohorts of patients undergoing exercise ECGand what else?. ### Response: stress imaging.


Instruction: Exercise ECG and stress imaging have shown that adding imaging provides incremental benefit in terms of what?

Output: diagnostic and prognostic information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise ECG and stress imaging have shown that adding imaging provides incremental benefit in terms of what?. ### Response: diagnostic and prognostic information.


Instruction: What are some other factors affecting test choice?

Output: the patient’s ability to exercise, body habitus, cardiacmedication use, and ECG interpretability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some other factors affecting test choice?. ### Response: the patient’s ability to exercise, body habitus, cardiacmedication use, and ECG interpretability.


Instruction: What is one form of testing better suited for?

Output: multiple diagnostic or prog-nostic questions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one form of testing better suited for?. ### Response: multiple diagnostic or prog-nostic questions.


Instruction: What can echocardiographic, radionuclide, and CMR stressimaging do?

Output: complementary roles for estimating patientprognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can echocardiographic, radionuclide, and CMR stressimaging do?. ### Response: complementary roles for estimating patientprognosis.


Instruction: What are complementary roles for estimating patientprognosis?

Output: echocardiographic, radionuclide, and CMR stressimaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are complementary roles for estimating patientprognosis?. ### Response: echocardiographic, radionuclide, and CMR stressimaging.


Instruction: What is rarely a reason to perform multiple tests in the same patient?

Output: unless the results of the initial imaging testare unsatisfactory for technical reasons or the findings areequivocal or require confirmation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rarely a reason to perform multiple tests in the same patient?. ### Response: unless the results of the initial imaging testare unsatisfactory for technical reasons or the findings areequivocal or require confirmation.


Instruction: Exercise Versus what?

Output: Pharmacological Testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise Versus what?. ### Response: Pharmacological Testing.


Instruction: What type of testing is preferred when a patient is able to perform routine activities of dailyliving without difficulty?

Output: exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of testing is preferred when a patient is able to perform routine activities of dailyliving without difficulty?. ### Response: exercise.


Instruction: Exercise testing to provoke ischemiais preferred because it often can provide a higher what?

Output: physiolog-

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise testing to provoke ischemiais preferred because it often can provide a higher what?. ### Response: physiolog-.


Instruction: What does 320-MDCT do?

Output: CT angiography and perfusion methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does 320-MDCT do?. ### Response: CT angiography and perfusion methods.


Instruction: What is the full text of Stable Ischemic Heart Disease?

Output: e439

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the full text of Stable Ischemic Heart Disease?. ### Response: e439.


Instruction: When was this article published?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: May 1, 2023.


Instruction: What is 222MAT commonly associated with?

Output: underlying conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 222MAT commonly associated with?. ### Response: underlying conditions.


Instruction: What is the first-line treatment?

Output: management of the underlying condition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first-line treatment?. ### Response: management of the underlying condition.


Instruction: Antiarrhythmic medications in general are what?

Output: not helpful in suppression of multifocal AT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antiarrhythmic medications in general are what?. ### Response: not helpful in suppression of multifocal AT.


Instruction: What is not helpful in suppression of multifocal AT?

Output: Antiarrhythmic medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not helpful in suppression of multifocal AT?. ### Response: Antiarrhythmic medications.


Instruction: Management often involves slowing conduction at the A V nodal level to control what?

Output: heart rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Management often involves slowing conduction at the A V nodal level to control what?. ### Response: heart rate.


Instruction: What has been shown to have some efficacy?

Output: Verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to have some efficacy?. ### Response: Verapamil.


Instruction: Who published the 2018 Cholesterol Clinical Practice Guidelines?

Output: Grundy et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2018 Cholesterol Clinical Practice Guidelines?. ### Response: Grundy et al.


Instruction: When did Grundy and colleagues publish the 2018 CHOLOSTERO CLINICAL STATEMENTS AND GUIDELINES?

Output: June 18/25, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Grundy and colleagues publish the 2018 CHOLOSTERO CLINICAL STATEMENTS AND GUIDELINES?. ### Response: June 18/25, 2019.


Instruction: What did Loprinzi PD and Addoh O do to predict all-cause and cardiovascular disease-specific mortality?

Output: Predictive validity of the American College of Cardiology/American Heart Association pooled cohort equa-tions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Loprinzi PD and Addoh O do to predict all-cause and cardiovascular disease-specific mortality?. ### Response: Predictive validity of the American College of Cardiology/American Heart Association pooled cohort equa-tions.


Instruction: What did Mortensen MB, Afzal S, Nordestgaard BG, et al. compare with risk-based approaches to guide statin therapy?

Output: ACC/AHA risk-based approach versus trial-based approaches

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Mortensen MB, Afzal S, Nordestgaard BG, et al. compare with risk-based approaches to guide statin therapy?. ### Response: ACC/AHA risk-based approach versus trial-based approaches.


Instruction: What was the name of the national prospective cohort study of adults in the United States?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the national prospective cohort study of adults in the United States?. ### Response: American College of Cardiology/American Heart Association.


Instruction: What is the difference between ACC/AHA and ESC/EAS guidelines for primary prevention with statins in non-diabetic Europeans?

Output: superior

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between ACC/AHA and ESC/EAS guidelines for primary prevention with statins in non-diabetic Europeans?. ### Response: superior.


Instruction: What was the Copenhagen General Population Study?

Output: statins in non-diabetic Europeans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Copenhagen General Population Study?. ### Response: statins in non-diabetic Europeans.


Instruction: What does MESA stand for?

Output: Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MESA stand for?. ### Response: Multi-Ethnic Study of Atherosclerosis.


Instruction: What is the acronym for the Multi-Ethnic Study of Atherosclerosis?

Output: MESA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Multi-Ethnic Study of Atherosclerosis?. ### Response: MESA.


Instruction: What is the name of the multiethnic population in which the ath-erosclerotic cardiovascular risk equation is accurate?

Output: Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multiethnic population in which the ath-erosclerotic cardiovascular risk equation is accurate?. ### Response: Multi-Ethnic Study of Atherosclerosis.


Instruction: When did the J Am Coll Cardiol. 201667:2118–30.

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol. 201667:2118–30.. ### Response: 2016.


Instruction: What is a risk factor for car -diovascular disease in patients?

Output: sarcoidosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for car -diovascular disease in patients?. ### Response: sarcoidosis.


Instruction: What is the risk of car -diovascular disease in patients with sarcoidosis?

Output: estimate accurately

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of car -diovascular disease in patients with sarcoidosis?. ### Response: estimate accurately.


Instruction: What study predicts the 30-year risk of cardiovascular disease?

Output: Framingham Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study predicts the 30-year risk of cardiovascular disease?. ### Response: Framingham Heart Study.


Instruction: How long did the Framingham Heart Study last?

Output: 30-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Framingham Heart Study last?. ### Response: 30-year.


Instruction: What is a risk factor burden at 50 years of age?

Output: Prediction of lifetime risk for cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor burden at 50 years of age?. ### Response: Prediction of lifetime risk for cardiovascular disease.


Instruction: What is the acronym for Risk-Enhancing Factors?

Output: S4.4.1.3-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Risk-Enhancing Factors?. ### Response: S4.4.1.3-1.


Instruction: Where can you find the ASCVD Risk Predictor Plus?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the ASCVD Risk Predictor Plus?. ### Response: http://tools.acc.org/ASCVD-Risk-Estimator-Plus/#!/calculate/estimate/..


Instruction: What is the ACC/AHA guideline on the treatment of blood cholesterol to reduce ath-erosclerotic cardiovascular risk in adults?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA guideline on the treatment of blood cholesterol to reduce ath-erosclerotic cardiovascular risk in adults?. ### Response: 2013.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce ath-erosclerotic cardiovascular risk in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce ath-erosclerotic cardiovascular risk in adults.


Instruction: What is the name of the Task Force on Practice Guidelines?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Practice Guidelines?. ### Response: American College of Cardiology/American Heart Association.


Instruction: When was the Circulation.129:S1–45. S4.4.1.3-3?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.129:S1–45. S4.4.1.3-3?. ### Response: 2014.


Instruction: What is lowering cholesterol in intermediate-risk persons without cardiovascular disease?

Output: Cholesterol lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lowering cholesterol in intermediate-risk persons without cardiovascular disease?. ### Response: Cholesterol lowering.


Instruction: Where is the N Engl J Med?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the N Engl J Med?. ### Response: 2016.


Instruction: What does coro-nary artery calcium testing do for statin candidates?

Output: Implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does coro-nary artery calcium testing do for statin candidates?. ### Response: Implications.


Instruction: What does a valve interven-tion leave the patient with?

Output: either a prosthetic valve or a valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a valve interven-tion leave the patient with?. ### Response: either a prosthetic valve or a valve repair.


Instruction: What does valve intervention replace?

Output: native valve disease with palliated valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does valve intervention replace?. ### Response: native valve disease with palliated valve disease.


Instruction: Patients with VHD con-tinue to require what?

Output: periodic evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with VHD con-tinue to require what?. ### Response: periodic evaluation.


Instruction: What type of valve disease requires periodic evaluation after intervention?

Output: VHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve disease requires periodic evaluation after intervention?. ### Response: VHD.


Instruction: Patients with VHD require what type of mechanical support?

Output: Temporary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with VHD require what type of mechanical support?. ### Response: Temporary.


Instruction: What is an example of an intra-aortic balloon counterpulsation?

Output: Temporary mechanical support (including percutaneous support devices such as intra-aortic balloon counterpulsation, temporary percutaneous ventricular assist device or ECMO)Temporary mechanical support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an intra-aortic balloon counterpulsation?. ### Response: Temporary mechanical support (including percutaneous support devices such as intra-aortic balloon counterpulsation, temporary percutaneous ventricular assist device or ECMO)Temporary mechanical support.


Instruction: What is a term for a temporary percutaneous ventricular assist device?

Output: ECMO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for a temporary percutaneous ventricular assist device?. ### Response: ECMO.


Instruction: What are the criteria for institutional facilities and infrastructure?

Output: IAC echocardiography laboratory accreditation IAC echocardiography laboratory accreditation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the criteria for institutional facilities and infrastructure?. ### Response: IAC echocardiography laboratory accreditation IAC echocardiography laboratory accreditation.


Instruction: What is the 24/7 intensivist coverage for ICU?

Output: IAC echocardiography laboratory accreditation IAC echocardiography laboratory accreditation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 24/7 intensivist coverage for ICU?. ### Response: IAC echocardiography laboratory accreditation IAC echocardiography laboratory accreditation.


Instruction: A primary (Level II) Center may provide what?

Output: additional procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A primary (Level II) Center may provide what?. ### Response: additional procedures.


Instruction: What type of center is offered as long as the criteria for competence and outcomes are met?

Output: Comprehensive (Level I) Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of center is offered as long as the criteria for competence and outcomes are met?. ### Response: Comprehensive (Level I) Center.


Instruction: If intraoperative imaging and surgical expertise exist, what is offered at a Comprehensive Center?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If intraoperative imaging and surgical expertise exist, what is offered at a Comprehensive Center?. ### Response: †.


Instruction: What is not suitable for valve repair?

Output: mitral valve anatomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not suitable for valve repair?. ### Response: mitral valve anatomy.


Instruction: What does flat-panel fluoroscopy offer?

Output: catheterization laboratory-quality imaging and hemodynamic capability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does flat-panel fluoroscopy offer?. ### Response: catheterization laboratory-quality imaging and hemodynamic capability.


Instruction: What does AVR stand for?

Output: aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AVR stand for?. ### Response: aortic valve replacement.


Instruction: CT stands for what?

Output: computed tomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CT stands for what?. ### Response: computed tomography.


Instruction: ECMO stands for extracorporeal membrane oxygenation?

Output: temporary percutaneous ventricular assist device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ECMO stands for extracorporeal membrane oxygenation?. ### Response: temporary percutaneous ventricular assist device.


Instruction: IAC stands for which type of defibrillator?

Output: implantable cardioverter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: IAC stands for which type of defibrillator?. ### Response: implantable cardioverter.


Instruction: What is the acronym for surgical aortic valve replacement?

Output: SAVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for surgical aortic valve replacement?. ### Response: SAVR.


Instruction: What is TEER?

Output: transcatheter edge-to-edge repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TEER?. ### Response: transcatheter edge-to-edge repair.


Instruction: Where is VHD located?

Output: valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is VHD located?. ### Response: valvular heart disease.


Instruction: What is the name of the Valve Center that was downloaded from http://ahajournals.org by on April 27, 2023?

Output: Valve Center Primary (Level II) Valve Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Valve Center that was downloaded from http://ahajournals.org by on April 27, 2023?. ### Response: Valve Center Primary (Level II) Valve Center.


Instruction: What was the date of 1402 Hypertension?

Output: June 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the date of 1402 Hypertension?. ### Response: June 2015.


Instruction: What is Valsartan in Acute Myocardial Infarction Trial Investigators?

Output: captopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Valsartan in Acute Myocardial Infarction Trial Investigators?. ### Response: captopril.


Instruction: What drug is used in acute myocardial infarction?

Output: Valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used in acute myocardial infarction?. ### Response: Valsartan.


Instruction: What is another name for Valsartan?

Output: captopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Valsartan?. ### Response: captopril.


Instruction: When was the N Engl J Med 349:1893-1906?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 349:1893-1906?. ### Response: 2003.


Instruction: Who is the ACCOMPLISH Trial Investigator?

Output: Jamerson K, Weber MA, Bakris GL, Dahlof B, Pitt B, Shi V , Hester A, Gupte J, Gatlin M, Velazequez EJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the ACCOMPLISH Trial Investigator?. ### Response: Jamerson K, Weber MA, Bakris GL, Dahlof B, Pitt B, Shi V , Hester A, Gupte J, Gatlin M, Velazequez EJ.


Instruction: What does Benazepril plus amlodipine or hydrochlorothiazide do for hypertension in high-risk patients?

Output: Major outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Benazepril plus amlodipine or hydrochlorothiazide do for hypertension in high-risk patients?. ### Response: Major outcomes.


Instruction: When did N Engl J Med. 2008:359:2417-2428?

Output: 93

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med. 2008:359:2417-2428?. ### Response: 93.


Instruction: What is the average diastolic blood pressure?

Output: 90 through 114 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average diastolic blood pressure?. ### Response: 90 through 114 mm Hg.


Instruction: When was the JAMA published?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 2002.


Instruction: What was the main result of the MRC trial?

Output: treatment of mild hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the main result of the MRC trial?. ### Response: treatment of mild hypertension.


Instruction: What is the name of the Systolic Hypertension in the Elderly Program?

Output: SHEP): SHEP Cooperative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Systolic Hypertension in the Elderly Program?. ### Response: SHEP): SHEP Cooperative Research Group.


Instruction: When was SHEP Cooperative Research Group founded?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was SHEP Cooperative Research Group founded?. ### Response: 1991.


Instruction: What was the main outcome of the ALLHAT Collaborative Research Group?

Output: high-risk hyperten-sive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the main outcome of the ALLHAT Collaborative Research Group?. ### Response: high-risk hyperten-sive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic.


Instruction: What is the name of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?

Output: ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?. ### Response: ALLHAT.


Instruction: What are the major outcomes in high-risk hyperten-sive patients randomized to?

Output: angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the major outcomes in high-risk hyperten-sive patients randomized to?. ### Response: angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic.


Instruction: What is the name of the study that investigated the adverse prognostic signifi-cance of new diabetes in treated hypertensive subjects?

Output: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the adverse prognostic signifi-cance of new diabetes in treated hypertensive subjects?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.


Instruction: What was the title of this study?

Output: ACCOMPLISH Trial Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of this study?. ### Response: ACCOMPLISH Trial Investigators.


Instruction: In what year did Hypertension 43:963-969?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Hypertension 43:963-969?. ### Response: 2004.


Instruction: What is the name of the study that evaluated antihypertensive and lipid-lowering treatment to prevent heart attack?

Output: ALLHAT Collaborative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated antihypertensive and lipid-lowering treatment to prevent heart attack?. ### Response: ALLHAT Collaborative Research Group.


Instruction: What is lisinopril used for in nondiabetic individuals?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lisinopril used for in nondiabetic individuals?. ### Response: hypertension.


Instruction: What is the name of the trial that evaluated lisinopril as an initial treatment for hypertension?

Output: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that evaluated lisinopril as an initial treatment for hypertension?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.


Instruction: What is ALHAT?

Output: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ALHAT?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.


Instruction: Diabetes Care. 2008;31:353–360.

Output: 98

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diabetes Care. 2008;31:353–360.. ### Response: 98.


Instruction: What is the name of the research group that studies mortality and morbidity during and after the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?

Output: ALLHAT Collaborative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the research group that studies mortality and morbidity during and after the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?. ### Response: ALLHAT Collaborative Research Group.


Instruction: What is Lipid-Lowering Treatment to Prevent Heart Attack?

Output: Antihypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Lipid-Lowering Treatment to Prevent Heart Attack?. ### Response: Antihypertensive.


Instruction: What is Greenwich's J Clin Hypertens?

Output: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Greenwich's J Clin Hypertens?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.


Instruction: LMWHs have a longer half-life than what other drug?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LMWHs have a longer half-life than what other drug?. ### Response: heparin.


Instruction: What is a lower risk of nonhemorrhagic side effects?

Output: more predictable pharmacokinetic and pharmacodynamic properties, have a longer half-life than heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a lower risk of nonhemorrhagic side effects?. ### Response: more predictable pharmacokinetic and pharmacodynamic properties, have a longer half-life than heparin.


Instruction: What has replaced UFH for many clinical indications?

Output: LMWHs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has replaced UFH for many clinical indications?. ### Response: LMWHs.


Instruction: What catalyzes the inhibition of factor Xa but not thrombin?

Output: Fonda-parinux

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What catalyzes the inhibition of factor Xa but not thrombin?. ### Response: Fonda-parinux.


Instruction: Fonda-parinux binds only to what?

Output: antithrombin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fonda-parinux binds only to what?. ### Response: antithrombin.


Instruction: What does Fondaparinux exhibit when administered subcutaneously?

Output: complete bio-availability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Fondaparinux exhibit when administered subcutaneously?. ### Response: complete bio-availability.


Instruction: What is a longer half-life than LMWHs?

Output: Fondaparinux

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a longer half-life than LMWHs?. ### Response: Fondaparinux.


Instruction: How many addi-tional parenteral direct thrombin inhibitors are approved as alternatives to hep-arin?

Output: Three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many addi-tional parenteral direct thrombin inhibitors are approved as alternatives to hep-arin?. ### Response: Three.


Instruction: What is an alternative to hep-arin in patients with HIT?

Output: danaparoid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an alternative to hep-arin in patients with HIT?. ### Response: danaparoid.


Instruction: What is aPTT 5 activated partial thromboplastin time?

Output: aPTT  5  activated partial thromboplastin time; AT  5  antithrombin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aPTT 5 activated partial thromboplastin time?. ### Response: aPTT  5  activated partial thromboplastin time; AT  5  antithrombin.


Instruction: What is 5 heparin cofactor II?

Output: HCII

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 5 heparin cofactor II?. ### Response: HCII.


Instruction: What is HIT 5?

Output: heparin-induced thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HIT 5?. ### Response: heparin-induced thrombocytopenia.