Instruction: What did the committee agree was a marked decrease?

Output: hospitalisations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee agree was a marked decrease?. ### Response: hospitalisations.


Instruction: There was no clinical effect shown on what?

Output: exercise tolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There was no clinical effect shown on what?. ### Response: exercise tolerance.


Instruction: What was the difference between placebo and placebo for discontinuation?

Output: less than 50 per 1000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between placebo and placebo for discontinuation?. ### Response: less than 50 per 1000.


Instruction: What did the committee agree about the impact on systolic function?

Output: The committee also agreed that the impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee agree about the impact on systolic function?. ### Response: The committee also agreed that the impact.


Instruction: What is a reasonable goal for most patients after CABG to reduce microvascular diabetic complications and macrovascular cardiovas-cular disease?

Output: Striving to achieve an HbA1c of 7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable goal for most patients after CABG to reduce microvascular diabetic complications and macrovascular cardiovas-cular disease?. ### Response: Striving to achieve an HbA1c of 7%.


Instruction: How many deaths resulted from tobacco use in the 20th century?

Output: ≈100 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths resulted from tobacco use in the 20th century?. ### Response: ≈100 million.


Instruction: How many more deaths may occur in the 21st century according to estimates?

Output: 1 billion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many more deaths may occur in the 21st century according to estimates?. ### Response: 1 billion.


Instruction: Compared with those who have never smoked tobacco, smokers lose how many years of life expec-tancy?

Output: ≈1 decade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Compared with those who have never smoked tobacco, smokers lose how many years of life expec-tancy?. ### Response: ≈1 decade.


Instruction: What can be lowered through smoking cessation?

Output: mortality risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be lowered through smoking cessation?. ### Response: mortality risk.


Instruction: What is the reduction in risk associated with smoking?

Output: ≈90%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reduction in risk associated with smoking?. ### Response: ≈90%..


Instruction: How does the risk of cardiovascular disease increase with smoking exposure?

Output: dose-response fashion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the risk of cardiovascular disease increase with smoking exposure?. ### Response: dose-response fashion.


Instruction: What does smoke exposure increase in a dose-response fashion?

Output: The risk of cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does smoke exposure increase in a dose-response fashion?. ### Response: The risk of cardiovascular disease.


Instruction: What is the greatest increase in risk occurring in individuals who have no cigarette exposure compared with those who have low levels of exposure?

Output: The risk of cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the greatest increase in risk occurring in individuals who have no cigarette exposure compared with those who have low levels of exposure?. ### Response: The risk of cardiovascular disease.


Instruction: When was the Downloaded from http://ahajournals.org?

Output: April 26, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Downloaded from http://ahajournals.org?. ### Response: April 26, 2023.


Instruction: What is otic treatment of endocarditis?

Output: prosthetic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is otic treatment of endocarditis?. ### Response: prosthetic valve.


Instruction: What is the name of the community teaching hospital?

Output: Grady Memorial Hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the community teaching hospital?. ### Response: Grady Memorial Hospital.


Instruction: How many cases of Staphylococcus aureus were analysed?

Output: 106

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of Staphylococcus aureus were analysed?. ### Response: 106.


Instruction: How did Grady Memorial Hospital experience with Staphylococcus aureus and endocarditis?

Output: meth-icillin-sensitive S aureus and methicillin-resistant S aureus bacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Grady Memorial Hospital experience with Staphylococcus aureus and endocarditis?. ### Response: meth-icillin-sensitive S aureus and methicillin-resistant S aureus bacteremia.


Instruction: What was the Am Heart J. 2004:147:536–9.

Output: S aureus bacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Am Heart J. 2004:147:536–9.. ### Response: S aureus bacteremia.


Instruction: What did Kaasch AJ, Fowler VG Jr, Rieg S, et al. use of a simple criteria set for?

Output: guid-ing echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Kaasch AJ, Fowler VG Jr, Rieg S, et al. use of a simple criteria set for?. ### Response: guid-ing echocardiography.


Instruction: How many prospectively identified cases with follow-up did Fowler VG Jr, Sanders LL, Kong LK, and et al. have infective endocarditis due to Staphylococcus aureus?

Output: 59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prospectively identified cases with follow-up did Fowler VG Jr, Sanders LL, Kong LK, and et al. have infective endocarditis due to Staphylococcus aureus?. ### Response: 59.


Instruction: How many prospectively identified Staphylococcus aureus cases with follow-up were identified?

Output: 59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prospectively identified Staphylococcus aureus cases with follow-up were identified?. ### Response: 59.


Instruction: What was the name of the 1999 issue of Clin Infect Dis?

Output: 28:106–14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the 1999 issue of Clin Infect Dis?. ### Response: 28:106–14.


Instruction: When did San Martin J, Sarriá C, de las Cuevas C, et al. publish their findings?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did San Martin J, Sarriá C, de las Cuevas C, et al. publish their findings?. ### Response: 1999.


Instruction: No LV enlargementNormal pulmonary pressureNoneC Asymptomatic severe MRS severe mitral valve prolapse with loss of coaptation or flail leafletRheumatic valve changes with leaflet restriction and loss of what?

Output: central coaptation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No LV enlargementNormal pulmonary pressureNoneC Asymptomatic severe MRS severe mitral valve prolapse with loss of coaptation or flail leafletRheumatic valve changes with leaflet restriction and loss of what?. ### Response: central coaptation.


Instruction: What may be present at rest or with exercise?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be present at rest or with exercise?. ### Response: Pulmonary hypertension.


Instruction: What is symptomatic severe MR?

Output: Severe mitral valve prolapse with loss of coaptation or flail leaflet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is symptomatic severe MR?. ### Response: Severe mitral valve prolapse with loss of coaptation or flail leaflet.


Instruction: What is a symptomatic severe MR with loss of coaptation or flail leafletRheumatic valve changes with leaflet restriction and loss of what?

Output: Severe mitral valve prolapse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a symptomatic severe MR with loss of coaptation or flail leafletRheumatic valve changes with leaflet restriction and loss of what?. ### Response: Severe mitral valve prolapse.


Instruction: What type of jet MR is 40% LA or holosystolic eccentric jet?

Output: Central

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of jet MR is 40% LA or holosystolic eccentric jet?. ### Response: Central.


Instruction: How large is the MRVena contracta?

Output: ≥0.7 cm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How large is the MRVena contracta?. ### Response: ≥0.7 cm.


Instruction: What is the valve hemodynamic criteria for?

Output: assessment of MR severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the valve hemodynamic criteria for?. ### Response: assessment of MR severity.


Instruction: What does ERO indicate?

Output: effective regurgitant orifice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ERO indicate?. ### Response: effective regurgitant orifice.


Instruction: What does LA mean?

Output: left atrium/atrial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LA mean?. ### Response: left atrium/atrial.


Instruction: Infective endocarditis is what?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis is what?. ### Response: IE.


Instruction: What is the acronym for infective endocarditis?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for infective endocarditis?. ### Response: IE.


Instruction: What does LA stand for?

Output: left atrium/atrial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LA stand for?. ### Response: left atrium/atrial.


Instruction: Where is LVEF located?

Output: left ventricular ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is LVEF located?. ### Response: left ventricular ejection fraction.


Instruction: When was MR downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was MR downloaded?. ### Response: April 28, 2023.


Instruction: If the person's eGFR is 45ml/min/1.73 m2 or below, consider lower doses and/or slower titration of dose of what?

Output: ACE inhibitors or ARB s, mineralocorticoid receptor antagonists and digoxin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the person's eGFR is 45ml/min/1.73 m2 or below, consider lower doses and/or slower titration of dose of what?. ### Response: ACE inhibitors or ARB s, mineralocorticoid receptor antagonists and digoxin.


Instruction: For people with heart failure with reduced ejection fraction and chronic kidney disease, what should be considered?

Output: lower doses and/or slower titration of dose of ACE inhibitors or ARB s, mineralocorticoid receptor antagonists and digoxin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For people with heart failure with reduced ejection fraction and chronic kidney disease, what should be considered?. ### Response: lower doses and/or slower titration of dose of ACE inhibitors or ARB s, mineralocorticoid receptor antagonists and digoxin.


Instruction: What is the eGFR of chronic kidney disease?

Output: below 30 ml/min/1.73  m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the eGFR of chronic kidney disease?. ### Response: below 30 ml/min/1.73  m2.


Instruction: How many ml/min/1.73 m2?

Output: 45

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ml/min/1.73 m2?. ### Response: 45.


Instruction: What was the difference between lidocaine and placebo in survival to hospital discharge?

Output: better

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between lidocaine and placebo in survival to hospital discharge?. ### Response: better.


Instruction: What did a large meta-analysis of antiarrhythmic medi-cations show about the survival of patients with witnessed SCA?

Output: survival to hospital discharge with lidocaine was better than with placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a large meta-analysis of antiarrhythmic medi-cations show about the survival of patients with witnessed SCA?. ### Response: survival to hospital discharge with lidocaine was better than with placebo.


Instruction: Beta blockers were associated with a significant reduction in what?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beta blockers were associated with a significant reduction in what?. ### Response: mortality.


Instruction: What can be effective in suppressing recurrent VF in patients with MI?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be effective in suppressing recurrent VF in patients with MI?. ### Response: Beta blockers.


Instruction: What is a VT/VF storm?

Output: recurrent VT/VF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a VT/VF storm?. ### Response: recurrent VT/VF.


Instruction: What has been shown to improve survival at 1 week?

Output: beta blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to improve survival at 1 week?. ### Response: beta blocker.


Instruction: What was the main cause of mortality for those who did not survive?

Output: recurrent VF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the main cause of mortality for those who did not survive?. ### Response: recurrent VF.


Instruction: What was better at 1 year in those treated with a beta blocker?

Output: Survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was better at 1 year in those treated with a beta blocker?. ### Response: Survival.


Instruction: Other measures to reduce sympathetic tone include sedation and what else?

Output: general anesthesia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Other measures to reduce sympathetic tone include sedation and what else?. ### Response: general anesthesia.


Instruction: Epinephrine produces beneficial effects on what?

Output: patients during cardiac arrest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Epinephrine produces beneficial effects on what?. ### Response: patients during cardiac arrest.


Instruction: What is another term for vasoconstrictor?

Output: alpha-adrenergic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for vasoconstrictor?. ### Response: alpha-adrenergic.


Instruction: What does epinephrine do in cardiac arrest?

Output: produces beneficial effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does epinephrine do in cardiac arrest?. ### Response: produces beneficial effects.


Instruction: How can alpha-adrenergic effects increase coronary and cerebral perfusion pressure during CPR?

Output: Epinephrine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can alpha-adrenergic effects increase coronary and cerebral perfusion pressure during CPR?. ### Response: Epinephrine.


Instruction: The value and safety of what are controversial?

Output: beta-adrenergic effects of epinephrine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The value and safety of what are controversial?. ### Response: beta-adrenergic effects of epinephrine.


Instruction: What are the beta-adrenergic effects of epinephrine controversial because they may increase myocardial work?

Output: The value and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the beta-adrenergic effects of epinephrine controversial because they may increase myocardial work?. ### Response: The value and safety.


Instruction: What is the name of the one trial that assessed short-term and long-term outcomes when com-paring standard-dose epherine to placebo?

Output: S6-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the one trial that assessed short-term and long-term outcomes when com-paring standard-dose epherine to placebo?. ### Response: S6-1.


Instruction: How often is epi-nephrine administered intra-osseously?

Output: 3 to 5 minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often is epi-nephrine administered intra-osseously?. ### Response: 3 to 5 minutes.


Instruction: What was the benefit of standard-dose epi-neurogen?

Output: improved survival to hospital admission and improved return of spontaneous circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the benefit of standard-dose epi-neurogen?. ### Response: improved survival to hospital admission and improved return of spontaneous circulation.


Instruction: The study was underpowered for analysis of what two outcomes?

Output: survival to discharge with a good neurologic recovery, survival to discharge, or survival to hos-pital admission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The study was underpowered for analysis of what two outcomes?. ### Response: survival to discharge with a good neurologic recovery, survival to discharge, or survival to hos-pital admission.


Instruction: What was improved by the use of standard-dose epi-nephrine?

Output: survival to hospital admission and improved return of spontaneous circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was improved by the use of standard-dose epi-nephrine?. ### Response: survival to hospital admission and improved return of spontaneous circulation.


Instruction: What has been compared with the out-comes of high-dose epinepherine in a number of trials?

Output: survival to discharge with a good neurologic recovery, survival to discharge, or survival to hos-pital admission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been compared with the out-comes of high-dose epinepherine in a number of trials?. ### Response: survival to discharge with a good neurologic recovery, survival to discharge, or survival to hos-pital admission.


Instruction: What was more effective than lidocaine in terminating incessant VT with improved survival?

Output: Amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was more effective than lidocaine in terminating incessant VT with improved survival?. ### Response: Amiodarone.


Instruction: What year was Stroke July 2018Appendix. Continued5. What percentage of patients 18 y of age with a diagnosis of ICH for whom there is documentation that a dysphagia screening was performed within 24 h of admission?

Output: e254

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Stroke July 2018Appendix. Continued5. What percentage of patients 18 y of age with a diagnosis of ICH for whom there is documentation that a dysphagia screening was performed within 24 h of admission?. ### Response: e254.


Instruction: How long after admission is a dysphagia screening performed?

Output: 24 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after admission is a dysphagia screening performed?. ### Response: 24 h.


Instruction: What is the name of the screening tool used by the institution where the patient is receiving care?

Output: dysphagia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the screening tool used by the institution where the patient is receiving care?. ### Response: dysphagia.


Instruction: How old are all patients with a diagnosis of ICHE?

Output: ≥18 y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are all patients with a diagnosis of ICHE?. ### Response: ≥18 y.


Instruction: 18 y of age Length of stay >120 d?

Output: <18 y of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 18 y of age Length of stay >120 d?. ### Response: <18 y of age.


Instruction: Who was involved in a clinical trial related to stroke?

Output: All patients ≥18 y of age with a diagnosis of ICHExcluded patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was involved in a clinical trial related to stroke?. ### Response: All patients ≥18 y of age with a diagnosis of ICHExcluded patients.


Instruction: What would affect dysphagia screening?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would affect dysphagia screening?. ### Response: stroke.


Instruction: Who was discharged before 24 h?

Output: All patients ≥18 y of age with a diagnosis of ICHExcluded patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was discharged before 24 h?. ### Response: All patients ≥18 y of age with a diagnosis of ICHExcluded patients.


Instruction: When was the patient discharged?

Output: before 24 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the patient discharged?. ### Response: before 24 h.


Instruction: Why was dysphagia screening not indicated?

Output: coma, intubation, or that the patient was entirely dependent on enteral feeding (without oral intake of food, liquids, or medications) before hospitalization as a result of a chronic medical condition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was dysphagia screening not indicated?. ### Response: coma, intubation, or that the patient was entirely dependent on enteral feeding (without oral intake of food, liquids, or medications) before hospitalization as a result of a chronic medical condition.


Instruction: What could be a reason the patient was discharged before 24 h?

Output: dysphagia screening was not indicated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be a reason the patient was discharged before 24 h?. ### Response: dysphagia screening was not indicated.


Instruction: What is the term for enteral feeding before hospitalization as a result of a chronic medical condition?

Output: without oral intake of food, liquids, or medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for enteral feeding before hospitalization as a result of a chronic medical condition?. ### Response: without oral intake of food, liquids, or medications.


Instruction: Within 24 h of hospital admission, what is the period of assessment?

Output: Period of Assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Within 24 h of hospital admission, what is the period of assessment?. ### Response: Period of Assessment.


Instruction: What is a retrospective medical record review?

Output: Prospective flowsheet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a retrospective medical record review?. ### Response: Prospective flowsheet.


Instruction: Dysphagia is present in up to what percentage of patients with acute stroke?

Output: 67%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dysphagia is present in up to what percentage of patients with acute stroke?. ### Response: 67%.


Instruction: How many patients with stroke have aspiration, a prerequisite for what?

Output: almost 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with stroke have aspiration, a prerequisite for what?. ### Response: almost 50%.


Instruction: Up to what percent of patients who aspirate develop pneumonia?

Output: one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Up to what percent of patients who aspirate develop pneumonia?. ### Response: one third.


Instruction: How many patients who aspirate develop pneumonia?

Output: Up to one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients who aspirate develop pneumonia?. ### Response: Up to one third.


Instruction: Pneumonia is a serious complication of what?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pneumonia is a serious complication of what?. ### Response: stroke.


Instruction: What is associated with increased mortality?

Output: Pneumonia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with increased mortality?. ### Response: Pneumonia.


Instruction: How many swallow screening methods have been published in the literature?

Output: Several

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many swallow screening methods have been published in the literature?. ### Response: Several.


Instruction: What are the benefits and limitations of each swallow screening method?

Output: benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the benefits and limitations of each swallow screening method?. ### Response: benefits.


Instruction: Who published the 2015 AHA/ASA guidelines?

Output: Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2015 AHA/ASA guidelines?. ### Response: Guidelines for the Management of Spontaneous Intracerebral Hemorrhage.


Instruction: What should be performed in all patients before the initiation of oral antibiotics?

Output: A formal screening procedure for dysphagia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed in all patients before the initiation of oral antibiotics?. ### Response: A formal screening procedure for dysphagia.


Instruction: What are the guidelines for the management of Spontaneous Intracerebral Hemorrhage?

Output: 2015 AHA/ASA “Guidelines for the Management of Spontaneous Intracerebral Hemorrhage”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the guidelines for the management of Spontaneous Intracerebral Hemorrhage?. ### Response: 2015 AHA/ASA “Guidelines for the Management of Spontaneous Intracerebral Hemorrhage”.


Instruction: What should be performed in all patients before the initiation of oral intake to reduce the risk of pneumonia?

Output: A formal screening procedure for dysphagia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed in all patients before the initiation of oral intake to reduce the risk of pneumonia?. ### Response: A formal screening procedure for dysphagia.


Instruction: What is the Class I; Level of Evidence B?

Output: A formal screening procedure for dysphagia should be performed in all patients before the initiation of oral intake to reduce the risk of pneumonia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class I; Level of Evidence B?. ### Response: A formal screening procedure for dysphagia should be performed in all patients before the initiation of oral intake to reduce the risk of pneumonia.


Instruction: Documentation of whether the patient received what?

Output: a dysphagia screen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Documentation of whether the patient received what?. ### Response: a dysphagia screen.


Instruction: Per patient: documentation of whether a patient received a dysphagia screen within 24 h of admission What is the percentage of patients who received systphia screens within 24 hours of admission?

Output: Percentage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Per patient: documentation of whether a patient received a dysphagia screen within 24 h of admission What is the percentage of patients who received systphia screens within 24 hours of admission?. ### Response: Percentage.


Instruction: What are the challenges to implementation?

Output: Documentation of timing of dysphagia screen may be difficult to locate in chart review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the challenges to implementation?. ### Response: Documentation of timing of dysphagia screen may be difficult to locate in chart review.


Instruction: How long after admission does dysphagia screen?

Output: 24 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after admission does dysphagia screen?. ### Response: 24 h.


Instruction: What may be difficult to locate in chart review?

Output: Documentation of timing of dysphagia screen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be difficult to locate in chart review?. ### Response: Documentation of timing of dysphagia screen.


Instruction: What is required of institutional dysphagia screening protocols?

Output: developed and that adherence to these protocols can be abstracted from the chart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required of institutional dysphagia screening protocols?. ### Response: developed and that adherence to these protocols can be abstracted from the chart.


Instruction: What can be abstracted from the chart?

Output: institutional dysphagia screening protocols

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be abstracted from the chart?. ### Response: institutional dysphagia screening protocols.


Instruction: How many consecutive cases can one submit to meet the case volume requirement?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many consecutive cases can one submit to meet the case volume requirement?. ### Response: 25.


Instruction: What is the alternative to submit a log of 25 consecutive cases?

Output: For thosewho cannot meet the case volume requirement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the alternative to submit a log of 25 consecutive cases?. ### Response: For thosewho cannot meet the case volume requirement.


Instruction: The mainte-nance of certification process is likely to change as what?

Output: American Board of Internal Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The mainte-nance of certification process is likely to change as what?. ### Response: American Board of Internal Medicine.


Instruction: What should be performed by opera-tors with an acceptable annual volume ( >75 proce-dures) at high-volume centers ( >400 procedures)?

Output: Elective/urgent PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed by opera-tors with an acceptable annual volume ( >75 proce-dures) at high-volume centers ( >400 procedures)?. ### Response: Elective/urgent PCI.


Instruction: How many procedures are performed at high-volume centers?

Output: >400

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many procedures are performed at high-volume centers?. ### Response: >400.


Instruction: What should be performed by opera-tors and institutions whose current risk-adjustedoutcomes statistics are comparable to those reported in contemporary national data registries?

Output: Elective/urgent PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed by opera-tors and institutions whose current risk-adjustedoutcomes statistics are comparable to those reported in contemporary national data registries?. ### Response: Elective/urgent PCI.


Instruction: Who should perform Primary PCI for STEMI?

Output: experienced operators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should perform Primary PCI for STEMI?. ### Response: experienced operators.


Instruction: Who should perform primary PCI for STEMI?

Output: experienced operators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should perform primary PCI for STEMI?. ### Response: experienced operators.


Instruction: How many elective PCIs peryear should an insti-tution perform?

Output: more than 400

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many elective PCIs peryear should an insti-tution perform?. ### Response: more than 400.


Instruction: How many elective PCIs are performed per year?

Output: 400

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many elective PCIs are performed per year?. ### Response: 400.


Instruction: How many primary PCI procedures are performed for STEMI peryear?

Output: 36

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many primary PCI procedures are performed for STEMI peryear?. ### Response: 36.


Instruction: What is the level of evidence for ELEctive/urgent PCI at low volume centers?

Output: 200 to 400PCI procedures per year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for ELEctive/urgent PCI at low volume centers?. ### Response: 200 to 400PCI procedures per year.


Instruction: How many PCI procedures per year are performed at low-volume centers?

Output: 200 to 400

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many PCI procedures per year are performed at low-volume centers?. ### Response: 200 to 400.


Instruction: What type of surgery is performed on-site?

Output: cardiac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery is performed on-site?. ### Response: cardiac.


Instruction: How many procedures per year should operators perform?

Output: fewer than 75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many procedures per year should operators perform?. ### Response: fewer than 75.


Instruction: What should operators develop with a highly experienced oper-ator?

Output: a defined men-toring relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should operators develop with a highly experienced oper-ator?. ### Response: a defined men-toring relationship.


Instruction: How many procedures per year does a highly experienced oper-ator have?

Output: 150

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many procedures per year does a highly experienced oper-ator have?. ### Response: 150.


Instruction: What is the benefit of primary PCI for STEMI patientseligible for fibrinolysis?

Output: is not wellestablished

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of primary PCI for STEMI patientseligible for fibrinolysis?. ### Response: is not wellestablished.


Instruction: How many PCIs per year do oper-ators perform?

Output: 75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many PCIs per year do oper-ators perform?. ### Response: 75.


Instruction: Who performs fewer than 75 procedures peryear?

Output: an oper-ator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who performs fewer than 75 procedures peryear?. ### Response: an oper-ator.


Instruction: How many procedures per year is not well established?

Output: fewer than 75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many procedures per year is not well established?. ### Response: fewer than 75.


Instruction: How many PCIs for STEMI per year?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many PCIs for STEMI per year?. ### Response: 11.


Instruction: Where was the 2011 ACCF/AHA/SCAI PCI Guideline e619 downloaded?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the 2011 ACCF/AHA/SCAI PCI Guideline e619 downloaded?. ### Response: http://ahajournals.org.


Instruction: What does Vitamin E do for coronary bypass operations?

Output: Plasma vitamin E and A changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Vitamin E do for coronary bypass operations?. ### Response: Plasma vitamin E and A changes.


Instruction: What is a prospective, double-blind, randomized trial?

Output: Vitamin E for coronary bypass operations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prospective, double-blind, randomized trial?. ### Response: Vitamin E for coronary bypass operations.


Instruction: What is plasma anti-oxidant depletion after cardiopulmonary bypass in operations for con-genital heart disease?

Output: 110:165–171

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is plasma anti-oxidant depletion after cardiopulmonary bypass in operations for con-genital heart disease?. ### Response: 110:165–171.


Instruction: What is Louw JA, Werbeck A, Louw ME, Kotze TJ, Cooper R, Labadarios D?

Output: Blood vitamin concentrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Louw JA, Werbeck A, Louw ME, Kotze TJ, Cooper R, Labadarios D?. ### Response: Blood vitamin concentrations.


Instruction: What does Labadarios D say about blood vitamin concentrations during the acute-phase response?

Output: Blood vitamin concentrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Labadarios D say about blood vitamin concentrations during the acute-phase response?. ### Response: Blood vitamin concentrations.


Instruction: What does Schindler R, Berndt S, Oster O, Rav G, Sievers HH say about plasma vitamin E and A changes during cardiopulmonary bypass and in the postoperative course?

Output: Blood vitamin concentrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Schindler R, Berndt S, Oster O, Rav G, Sievers HH say about plasma vitamin E and A changes during cardiopulmonary bypass and in the postoperative course?. ### Response: Blood vitamin concentrations.


Instruction: What year did Langenbecks Arch Surg publish 387:372–378?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Langenbecks Arch Surg publish 387:372–378?. ### Response: 2003.


Instruction: What is the name of the surgery that is associated with a marked Download from http://ahajournals.org by April 26, 2023?

Output: Coronary artery bypass grafting surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the surgery that is associated with a marked Download from http://ahajournals.org by April 26, 2023?. ### Response: Coronary artery bypass grafting surgery.


Instruction: What has been tested in a randomized trial?

Output: The role of bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been tested in a randomized trial?. ### Response: The role of bridging.


Instruction: What was performed in patients on warfarin whowere candidates for an invasive procedure?

Output: bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was performed in patients on warfarin whowere candidates for an invasive procedure?. ### Response: bridging.


Instruction: What was excluded?

Output: patientswith mechanical valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was excluded?. ### Response: patientswith mechanical valves.


Instruction: What was the risk of after the procedure?

Output: thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of after the procedure?. ### Response: thromboembolism.


Instruction: Who had a higher risk of major bleeding?

Output: those who werebridged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who had a higher risk of major bleeding?. ### Response: those who werebridged.


Instruction: What type of valve does not have a high risk of throm-boembolism?

Output: mechanical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve does not have a high risk of throm-boembolism?. ### Response: mechanical.


Instruction: In patients receiving NOACs, what is notrequired?

Output: bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients receiving NOACs, what is notrequired?. ### Response: bridging.


Instruction: What could be considered in thepostoperative phase if the patient cannot take oralmedications for a prolonged period?

Output: bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be considered in thepostoperative phase if the patient cannot take oralmedications for a prolonged period?. ### Response: bridging.


Instruction: What do we suggest in AF patients taking warfarin without high risk of thromboembolism or do not have a mechanical valve?

Output: preoperative management withoutbridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest in AF patients taking warfarin without high risk of thromboembolism or do not have a mechanical valve?. ### Response: preoperative management withoutbridging.


Instruction: What does weak recommendation, low qualityevidence suggest?

Output: preoperative management withoutbridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does weak recommendation, low qualityevidence suggest?. ### Response: preoperative management withoutbridging.


Instruction: What do we suggest in AF patients on antithrombotic prophylaxis with an NOAC?

Output: preoperative managementwithout bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest in AF patients on antithrombotic prophylaxis with an NOAC?. ### Response: preoperative managementwithout bridging.


Instruction: What are crucial to patient acceptance?

Output: Patient knowledge and understanding of the stroke riskassociated with AF and the bene ﬁt of OAC to preventstroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are crucial to patient acceptance?. ### Response: Patient knowledge and understanding of the stroke riskassociated with AF and the bene ﬁt of OAC to preventstroke.


Instruction: What is crucial to patient acceptance of anticoagulants?

Output: bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is crucial to patient acceptance of anticoagulants?. ### Response: bridging.


Instruction: What is important to patient adherence to OAC?

Output: life-longpersistence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to patient adherence to OAC?. ### Response: life-longpersistence.


Instruction: How is OAC fit to preventstroke?

Output: bene

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is OAC fit to preventstroke?. ### Response: bene.


Instruction: What is another term for a clinic based heart failure disease management programme or home visiting?

Output: cardiology clinics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for a clinic based heart failure disease management programme or home visiting?. ### Response: cardiology clinics.


Instruction: Studies will be excluded if there was any previous exposure to what?

Output: telemonitoring or structured telephone support for the usual care or intervention arms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Studies will be excluded if there was any previous exposure to what?. ### Response: telemonitoring or structured telephone support for the usual care or intervention arms.


Instruction: What is the term for all-cause mortality during the study?

Output: dichotomous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for all-cause mortality during the study?. ### Response: dichotomous.


Instruction: What is another term for quality of life during the research?

Output: continuous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for quality of life during the research?. ### Response: continuous.


Instruction: How are the outcomes of the study determined?

Output: All-cause mortality during study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the outcomes of the study determined?. ### Response: All-cause mortality during study.


Instruction: What was the date of the e538 Circulation?

Output: April 5, 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the date of the e538 Circulation?. ### Response: April 5, 2016.


Instruction: What is the level of evidence for B-NR?

Output: 294–297

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for B-NR?. ### Response: 294–297.


Instruction: What is useful to identify patients at low risk of rapid conduction over the pathway?

Output: Noninvasive testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful to identify patients at low risk of rapid conduction over the pathway?. ### Response: Noninvasive testing.


Instruction: What has been shown to identify patients at low risk of developing rapid conduction over the accessory pathway and life-threatening ventricular arrhythmias in response to AF?

Output: Noninvasive testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to identify patients at low risk of developing rapid conduction over the accessory pathway and life-threatening ventricular arrhythmias in response to AF?. ### Response: Noninvasive testing.


Instruction: What is an example of an ECG that is not capable of maintaining rapid conduction during AF?

Output: intermittent loss of conduction over the accessory pathway on the resting ECG or during ambulatory monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an ECG that is not capable of maintaining rapid conduction during AF?. ### Response: intermittent loss of conduction over the accessory pathway on the resting ECG or during ambulatory monitoring.


Instruction: What should the ECG be evaluated closely to make sure the delta wave is truly absent?

Output: 294–297

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the ECG be evaluated closely to make sure the delta wave is truly absent?. ### Response: 294–297.


Instruction: What may show varying degrees of pre-excitation because of fusion between conduction over the accessory pathway and through the AV node?

Output: accessory pathways, especially left lateral pathways

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may show varying degrees of pre-excitation because of fusion between conduction over the accessory pathway and through the AV node?. ### Response: accessory pathways, especially left lateral pathways.


Instruction: The subtle delta wave may give the appearance of what?

Output: symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The subtle delta wave may give the appearance of what?. ### Response: symptoms.


Instruction: What percentage of positive predictive value do noninvasive tests have for identifying pathways with life-threatening properties?

Output: 90%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of positive predictive value do noninvasive tests have for identifying pathways with life-threatening properties?. ### Response: 90%.


Instruction: What is reasonable in asymptomatic patients with pre-excitation?

Output: Catheter ablation of the accessory pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in asymptomatic patients with pre-excitation?. ### Response: Catheter ablation of the accessory pathway.


Instruction: What is reasonable in asymptomatic patients with pre-excitation to risk-stratify for arrhythmic events?

Output: Catheter ablation of the accessory pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in asymptomatic patients with pre-excitation to risk-stratify for arrhythmic events?. ### Response: Catheter ablation of the accessory pathway.


Instruction: What is a clinical priority in the absence of symptoms?

Output: identifying accessory pathways at increased risk of arrhythmic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a clinical priority in the absence of symptoms?. ### Response: identifying accessory pathways at increased risk of arrhythmic events.


Instruction: How long is the R-R interval between 2 pre-excited complexes during induced AF?

Output: <250 ms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the R-R interval between 2 pre-excited complexes during induced AF?. ### Response: <250 ms.


Instruction: What is the ability to induce sustained AVRT?

Output: the presence of multiple accessory pathways

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ability to induce sustained AVRT?. ### Response: the presence of multiple accessory pathways.


Instruction: Malignant arrhythmias correlate more with the EP properties of the accessory pathway than with the presence or absence of what?

Output: symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Malignant arrhythmias correlate more with the EP properties of the accessory pathway than with the presence or absence of what?. ### Response: symptoms.


Instruction: Complication rates among 2169 patients ranged from 0.09% to what percentage?

Output: 1%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Complication rates among 2169 patients ranged from 0.09% to what percentage?. ### Response: 1%.


Instruction: What is reasonable in asymptomatic patients with pre-excitation if an EP study identifies a high risk of arrhythmic events?

Output: Catheter ablation of the accessory pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in asymptomatic patients with pre-excitation if an EP study identifies a high risk of arrhythmic events?. ### Response: Catheter ablation of the accessory pathway.


Instruction: What are the 2018 Cholesterol Clinical Practice Guidelines?

Output: e1127CLINICAL STATEMENTS  AND GUIDELINES S4.1-14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2018 Cholesterol Clinical Practice Guidelines?. ### Response: e1127CLINICAL STATEMENTS  AND GUIDELINES S4.1-14.


Instruction: What is the DOI of the 2018 CIR.0000000000000625 June 18/25, 2019?

Output: 10.1161

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI of the 2018 CIR.0000000000000625 June 18/25, 2019?. ### Response: 10.1161.


Instruction: Atherothrombotic risk stratification and what for secondary prevention?

Output: ezetimibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atherothrombotic risk stratification and what for secondary prevention?. ### Response: ezetimibe.


Instruction: What is ezetimibe added to statin therapy after acute coronary syndromes?

Output: Alirocumab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ezetimibe added to statin therapy after acute coronary syndromes?. ### Response: Alirocumab.


Instruction: What is cognitive function in a ran-domized trial of evolocumab?

Output: clini-cal outcomes in patients with cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cognitive function in a ran-domized trial of evolocumab?. ### Response: clini-cal outcomes in patients with cardiovascular disease.


Instruction: What is evolocumab used for in a ran-domized trial?

Output: Cognitive function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evolocumab used for in a ran-domized trial?. ### Response: Cognitive function.


Instruction: What is the name of the trial that was run by the N Engl J Med in 2017?

Output: evolocumab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that was run by the N Engl J Med in 2017?. ### Response: evolocumab.


Instruction: Who is the author of the study?

Output: Grundy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study?. ### Response: Grundy.


Instruction: How many patients were enrolled in the study that was conducted in the run-domed trial? What is Alirocumab and cardiovascular outcomes after?

Output: acute coronary syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the study that was conducted in the run-domed trial? What is Alirocumab and cardiovascular outcomes after?. ### Response: acute coronary syndrome.


Instruction: Alirocumab and cardiovas-cular outcomes after acute coronary syndrome. rosii What is the name of the systematic review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ADA/AGS/APhA/ASPC/ NLA/PCNA guideline on the management of blood cholesterol?

Output: N Engl J Med. 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Alirocumab and cardiovas-cular outcomes after acute coronary syndrome. rosii What is the name of the systematic review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ADA/AGS/APhA/ASPC/ NLA/PCNA guideline on the management of blood cholesterol?. ### Response: N Engl J Med. 2018.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines report on?

Output: management of blood cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines report on?. ### Response: management of blood cholesterol.


Instruction: What is the DOI for Circulation. 2019?

Output: 10.1161/CIR.0000000000000626

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI for Circulation. 2019?. ### Response: 10.1161/CIR.0000000000000626.


Instruction: Who wrote the report on PCSK9 inhibitors?

Output: Hlatky MA, Kazi DS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the report on PCSK9 inhibitors?. ### Response: Hlatky MA, Kazi DS.


Instruction: What is the cost-effectiveness of PCSK9 inhi-bitor therapy in patients with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease?

Output: Cost-effectiveness of PCSK9 inhi-bitor therapy in patients with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease. JAMA. 2016;316:743–53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of PCSK9 inhi-bitor therapy in patients with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease?. ### Response: Cost-effectiveness of PCSK9 inhi-bitor therapy in patients with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease. JAMA. 2016;316:743–53.


Instruction: JAMA. 2016;316:743–53. S4.1-22. Gandra SR, Villa G, Fonarow GC, and evolocumab are patients with high cardiovascular risk in what country?

Output: United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: JAMA. 2016;316:743–53. S4.1-22. Gandra SR, Villa G, Fonarow GC, and evolocumab are patients with high cardiovascular risk in what country?. ### Response: United States.


Instruction: What are statin drug interactions and related adverse reactions?

Output: safety issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are statin drug interactions and related adverse reactions?. ### Response: safety issues.


Instruction: What is the name of the study that examined statin use and clinical outcomes in older men?

Output: a prospective population-based study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined statin use and clinical outcomes in older men?. ### Response: a prospective population-based study.


Instruction: Statin use and clinical outcomes in older men: a prospective population-based study?

Output: Gnjidic D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Statin use and clinical outcomes in older men: a prospective population-based study?. ### Response: Gnjidic D.


Instruction: What is the BMJ Open 2013;3:e002333. S4.1-25. Gray SL, Boudreau RM, Newman AB, et al. What is angiotensin-converting enzyme inhibitor and statin use in community-dwelling older adults?

Output: incident mobility limitation in community-dwelling older adults: the Health, Aging and Body Composition study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BMJ Open 2013;3:e002333. S4.1-25. Gray SL, Boudreau RM, Newman AB, et al. What is angiotensin-converting enzyme inhibitor and statin use in community-dwelling older adults?. ### Response: incident mobility limitation in community-dwelling older adults: the Health, Aging and Body Composition study.


Instruction: What is the ageing and body composition study?

Output: J Am Geriatr Soc.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ageing and body composition study?. ### Response: J Am Geriatr Soc..


Instruction: What are statins and their interactions with other lipid-modifying medications in the elderly?

Output: safety issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are statins and their interactions with other lipid-modifying medications in the elderly?. ### Response: safety issues.


Instruction: Who is the author of Statin use and incident frailty?

Output: LaCroix AZ, Gray SL, Aragaki A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Statin use and incident frailty?. ### Response: LaCroix AZ, Gray SL, Aragaki A.


Instruction: Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women's Health Initiative Observal Study?

Output: LaCroix AZ, Gray SL, Aragaki A, et al. Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women’s Health Initiative Observational Study. J Gerontol A Biol Sci Med Sci. 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women's Health Initiative Observal Study?. ### Response: LaCroix AZ, Gray SL, Aragaki A, et al. Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women’s Health Initiative Observational Study. J Gerontol A Biol Sci Med Sci. 2008.


Instruction: J Gerontol A Biol Sci Med Sci. 2008;63:369–75.

Output: Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women’s Health Initiative Observational Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Gerontol A Biol Sci Med Sci. 2008;63:369–75.. ### Response: Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women’s Health Initiative Observational Study.


Instruction: Statin treatment and mortality in community-dwelling S4.1-frail older patients with statin?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Statin treatment and mortality in community-dwelling S4.1-frail older patients with statin?. ### Response: 25.


Instruction: Statin treatment and mortality in community-dwelling S4.1-frail older patients with diabetes mellitus:

Output: S4.1-28

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Statin treatment and mortality in community-dwelling S4.1-frail older patients with diabetes mellitus:. ### Response: S4.1-28.


Instruction: Who is the Chair of the ACC/AHA Task Force on Clinical Practice Guidelines?

Output: Glenn N. Levine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of the ACC/AHA Task Force on Clinical Practice Guidelines?. ### Response: Glenn N. Levine.


Instruction: When did the Build and Blood Pressure Study begin?

Output: 1959

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Build and Blood Pressure Study begin?. ### Response: 1959.


Instruction: How many adults were enrolled in the 1959 Build and Blood Pressure StudyS1.5-1 between 1934 and 1954?

Output: almost 5 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many adults were enrolled in the 1959 Build and Blood Pressure StudyS1.5-1 between 1934 and 1954?. ### Response: almost 5 million.


Instruction: What was the relationship between level of BP and risk of clinical complications and death?

Output: strong direct

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the relationship between level of BP and risk of clinical complications and death?. ### Response: strong direct.


Instruction: In what decade were the findings confirmed in a series of reports?

Output: 1960s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what decade were the findings confirmed in a series of reports?. ### Response: 1960s.


Instruction: In what year was the first comprehensive guideline for detec-tion, evaluation, and management of high BP published?

Output: 1977

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the first comprehensive guideline for detec-tion, evaluation, and management of high BP published?. ### Response: 1977.


Instruction: The Framingham Heart Study's findings were confirmed in a series of reports from what study?

Output: Veterans Administration Cooperative Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Framingham Heart Study's findings were confirmed in a series of reports from what study?. ### Response: Veterans Administration Cooperative Study Group.


Instruction: What ushered in the era of effective treatment for highBP?

Output: Veterans Administration Cooperative Study Group reports

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What ushered in the era of effective treatment for highBP?. ### Response: Veterans Administration Cooperative Study Group reports.


Instruction: When was the management of high BP published?

Output: 1977

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the management of high BP published?. ### Response: 1977.


Instruction: Who sponsored the publication of the BP management guideline in 1977?

Output: NHLBI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who sponsored the publication of the BP management guideline in 1977?. ### Response: NHLBI.


Instruction: What was the purpose of the JNC BP guideline?

Output: to assist the practice community and improve prevention, awareness, treatment, and control of high BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the purpose of the JNC BP guideline?. ### Response: to assist the practice community and improve prevention, awareness, treatment, and control of high BP.


Instruction: What does the present guideline update?

Output: prior JNC reports

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the present guideline update?. ### Response: prior JNC reports.


Instruction: What is the name of the extensive evidence review that included literature derived from research using human subjects?

Output: Methodology and Evidence Review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the extensive evidence review that included literature derived from research using human subjects?. ### Response: Methodology and Evidence Review.


Instruction: What did the Agency for Healthcare Research and Quality conduct between February and August 2015?

Output: extensive evidence review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Agency for Healthcare Research and Quality conduct between February and August 2015?. ### Response: extensive evidence review.


Instruction: What was the key word for adherence?

Output: aerobic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the key word for adherence?. ### Response: aerobic.


Instruction: What are beta adrener -gic blockers?

Output: blood pressure: arterial, control, determination, devices, goal, high, improve, measurement, monitoring, ambu-latory; calcium channel blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are beta adrener -gic blockers?. ### Response: blood pressure: arterial, control, determination, devices, goal, high, improve, measurement, monitoring, ambu-latory; calcium channel blockers.


Instruction: What is a diuretic agent?

Output: drug therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a diuretic agent?. ### Response: drug therapy.


Instruction: What is the name of a study published through June 2016?

Output: Additional relevant studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a study published through June 2016?. ### Response: Additional relevant studies.


Instruction: What is a risk reduction study?

Output: behavior, counseling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk reduction study?. ### Response: behavior, counseling.


Instruction: What did the writing com-mittee consider during the guide-line writing process?

Output: Additional relevant studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing com-mittee consider during the guide-line writing process?. ### Response: Additional relevant studies.


Instruction: What do the final evidence tables in the Online Data Supplement summarize?

Output: the evidence used by the writing committee to for -mulate recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the final evidence tables in the Online Data Supplement summarize?. ### Response: the evidence used by the writing committee to for -mulate recommendations.


Instruction: What did the committee use to for -mulate recommendations?

Output: data from clinical trials and other sources

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee use to for -mulate recommendations?. ### Response: data from clinical trials and other sources.


Instruction: Who was com-mitted to summarize the evidence?

Output: an independent ERC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was com-mitted to summarize the evidence?. ### Response: an independent ERC.


Instruction: How old were women in previous observational trials?

Output: 50 to 59 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old were women in previous observational trials?. ### Response: 50 to 59 years of age.


Instruction: What was the mean age of the women in the WHI?

Output: ≥65

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean age of the women in the WHI?. ### Response: ≥65.


Instruction: What did the WHI focus on?

Output: specific subgroups of women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the WHI focus on?. ### Response: specific subgroups of women.


Instruction: What were the subgroups of women at particularly high risk outlined in?

Output: previous AHA guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the subgroups of women at particularly high risk outlined in?. ### Response: previous AHA guidelines.


Instruction: The risk of stroke with CEE was limited to what?

Output: IS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The risk of stroke with CEE was limited to what?. ### Response: IS.


Instruction: What was the HR of women with no prior history of CVD than women with a prior history?

Output: 0.76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of women with no prior history of CVD than women with a prior history?. ### Response: 0.76.


Instruction: What is the 95% CI of women using HT?

Output: 0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% CI of women using HT?. ### Response: 0.


Instruction: What was the HR of women using HT who were 50 to 59 years of age?

Output: 1.09

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of women using HT who were 50 to 59 years of age?. ### Response: 1.09.


Instruction: What is the 95% CI of women who were 60 to 69?

Output: 1.17–2.54

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% CI of women who were 60 to 69?. ### Response: 1.17–2.54.


Instruction: Who had a lower risk than those who were 70 to 79?

Output: nonusers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who had a lower risk than those who were 70 to 79?. ### Response: nonusers.


Instruction: What is the HR of HT compared to nonusers?

Output: 1.72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the HR of HT compared to nonusers?. ### Response: 1.72.


Instruction: What was the 95% confidence interval between 1.02 and 2.29?

Output: 1.17–2.54

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 95% confidence interval between 1.02 and 2.29?. ### Response: 1.17–2.54.


Instruction: How did the risk estimates for HT vary?

Output: lower risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the risk estimates for HT vary?. ### Response: lower risk.


Instruction: What is evidence that HT is effective at preventing deterioration of cognitive function in postmenopausal women?

Output: little compelling evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evidence that HT is effective at preventing deterioration of cognitive function in postmenopausal women?. ### Response: little compelling evidence.


Instruction: What subgroup of women enrolled in the WHI found that for women 65 years of age, HT did not reduce the inci-dence of dementia or mild cognitive impairment?

Output: Women’s Health Initiative Memory Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What subgroup of women enrolled in the WHI found that for women 65 years of age, HT did not reduce the inci-dence of dementia or mild cognitive impairment?. ### Response: Women’s Health Initiative Memory Study.


Instruction: What did HT have an adverse effect on?

Output: global cognitive function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did HT have an adverse effect on?. ### Response: global cognitive function.


Instruction: What was greater among women with lower cognitive func-tion at initiation of treatment?

Output: global cognitive function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was greater among women with lower cognitive func-tion at initiation of treatment?. ### Response: global cognitive function.


Instruction: What was most evident in women experiencing cognitive deficits before HT?

Output: The adverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was most evident in women experiencing cognitive deficits before HT?. ### Response: The adverse effects.


Instruction: What has been reported in randomized clinical trials for selective estrogen receptor modulators?

Output: Similar results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been reported in randomized clinical trials for selective estrogen receptor modulators?. ### Response: Similar results.


Instruction: What is a commonly used therapy in Europe with both estrogenic and androgenic properties?

Output: tibolone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a commonly used therapy in Europe with both estrogenic and androgenic properties?. ### Response: tibolone.


Instruction: Raloxifene (60 mg ver -sus placebo) had no effect on the risk of nonfatal stroke (HR, 1.10; 95% CI, 0.92–1.32)?

Output: increased the risk of fatal strokes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Raloxifene (60 mg ver -sus placebo) had no effect on the risk of nonfatal stroke (HR, 1.10; 95% CI, 0.92–1.32)?. ### Response: increased the risk of fatal strokes.


Instruction: What increased the risk of nonfatal strokes?

Output: Raloxifene

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increased the risk of nonfatal strokes?. ### Response: Raloxifene.


Instruction: What is an increasing recognition that the timing of HT initiation may play a critical role in?

Output: the overall effect of HT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increasing recognition that the timing of HT initiation may play a critical role in?. ### Response: the overall effect of HT.


Instruction: What was the overall effect of HT?

Output: lower risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall effect of HT?. ### Response: lower risk.


Instruction: What was performed to test this hypothesis?

Output: An analysis of the WHI subjects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was performed to test this hypothesis?. ### Response: An analysis of the WHI subjects.


Instruction: Women 10 years post menopause had no increased risk of what?

Output: coronary heart disease events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Women 10 years post menopause had no increased risk of what?. ### Response: coronary heart disease events.


Instruction: What was the HR of women 20 years post menopause?

Output: 1.28

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of women 20 years post menopause?. ### Response: 1.28.


Instruction: What is a short QT syndrome?

Output: pharma-cological treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a short QT syndrome?. ### Response: pharma-cological treatment.


Instruction: What is the pharma-cological treatment?

Output: Short QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pharma-cological treatment?. ### Response: Short QT syndrome.


Instruction: When was the ahajournals.org downloaded?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ahajournals.org downloaded?. ### Response: April 23, 2023.


Instruction: What is a normalized ratio?

Output: INR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a normalized ratio?. ### Response: INR.


Instruction: What is an LMWH bridging therapy?

Output: periprocedural low-molecular-weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an LMWH bridging therapy?. ### Response: periprocedural low-molecular-weight heparin.


Instruction: Dosing, using specialized anticoagulation managementservices, and resuming anticoagulate after episodes of life-threatening bleeding are examples of what?

Output: Conditionalrecommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dosing, using specialized anticoagulation managementservices, and resuming anticoagulate after episodes of life-threatening bleeding are examples of what?. ### Response: Conditionalrecommendations.


Instruction: Anticoagulant therapy is complex and associated with both substantial benefits and what else?

Output: ri sks (life-threatening bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anticoagulant therapy is complex and associated with both substantial benefits and what else?. ### Response: ri sks (life-threatening bleeding complications.


Instruction: What is ri sks?

Output: life-threatening bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ri sks?. ### Response: life-threatening bleeding complications.


Instruction: What is another term for recurrentvenous thromboembolism?

Output: VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for recurrentvenous thromboembolism?. ### Response: VTE.


Instruction: How does one recognize and mitigate risk for harm from anticoagulants?

Output: evidence-based approach toanticoagulant management and patient education

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does one recognize and mitigate risk for harm from anticoagulants?. ### Response: evidence-based approach toanticoagulant management and patient education.


Instruction: What is one of the keymanagement strategies for optimal use of anticoagulants?

Output: initial anticoagulant dose selection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the keymanagement strategies for optimal use of anticoagulants?. ### Response: initial anticoagulant dose selection.


Instruction: When was the submission of the guidelines accepted?

Output: 24 September 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the submission of the guidelines accepted?. ### Response: 24 September 2018.


Instruction: Where can resources for implementing the guidelines be accessed?

Output: ASH web page hematology.org/vte

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can resources for implementing the guidelines be accessed?. ### Response: ASH web page hematology.org/vte.


Instruction: Where can sets be accessed at the ASH web page?

Output: hematology.org/vte

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can sets be accessed at the ASH web page?. ### Response: hematology.org/vte.


Instruction: What does the full-text version of this article contain?

Output: a data supplement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the full-text version of this article contain?. ### Response: a data supplement.


Instruction: What can epidemiological correlations not be used as proof of?

Output: the value of treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can epidemiological correlations not be used as proof of?. ### Response: the value of treatment.


Instruction: Epidemiological data do not necessarily predict cardiovascular outcomes when BP is lowered as a result of what?

Output: antihypertensive treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Epidemiological data do not necessarily predict cardiovascular outcomes when BP is lowered as a result of what?. ### Response: antihypertensive treatment.


Instruction: What is a result of antihypertensive treatment?

Output: BP is lowered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a result of antihypertensive treatment?. ### Response: BP is lowered.


Instruction: What do population studies provide some support for?

Output: “lower is better” strategy for BP control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do population studies provide some support for?. ### Response: “lower is better” strategy for BP control.


Instruction: The debate about lower BP targets revolves around what?

Output: the issue of the so-called J curve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The debate about lower BP targets revolves around what?. ### Response: the issue of the so-called J curve.


Instruction: What does the debate about lower BP targets revolve around?

Output: the issue of the so-called J curve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the debate about lower BP targets revolve around?. ### Response: the issue of the so-called J curve.


Instruction: What is the J curve?

Output: lower BP targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J curve?. ### Response: lower BP targets.


Instruction: How does lowering SBP, DBP, or both decrease overall cardiovascular risk?

Output: Many studies demonstrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does lowering SBP, DBP, or both decrease overall cardiovascular risk?. ### Response: Many studies demonstrate.


Instruction: What does lowering SBP, DBP, or both decrease?

Output: overall cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lowering SBP, DBP, or both decrease?. ### Response: overall cardiovascular risk.


Instruction: What may have adverse effects on cardiovascular risk?

Output: excessive DBP lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have adverse effects on cardiovascular risk?. ### Response: excessive DBP lowering.


Instruction: What is the single most important reason for the failure to administer thrombolytic treatment within the hospital?

Output: Delayed hospital arrival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the single most important reason for the failure to administer thrombolytic treatment within the hospital?. ### Response: Delayed hospital arrival.


Instruction: How long did the decline in 28-day case fatality for women and men last?

Output: 1991 to 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the decline in 28-day case fatality for women and men last?. ### Response: 1991 to 2002.


Instruction: What was the time period between 1991 and 2002?

Output: 12-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the time period between 1991 and 2002?. ### Response: 12-year.


Instruction: What is the eligible time window for thrombolytic treatment?

Output: 3 or 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the eligible time window for thrombolytic treatment?. ### Response: 3 or 4.5 hours.


Instruction: Most studies have not found important sex differences in what?

Output: delayed hospital arrival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most studies have not found important sex differences in what?. ### Response: delayed hospital arrival.


Instruction: What do women have longer prehospital delay than men?

Output: 76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do women have longer prehospital delay than men?. ### Response: 76.


Instruction: What are the most studies that have explored knowledge and awareness of stroke symptoms in stroke patients or at-risk populations?

Output: population-based studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the most studies that have explored knowledge and awareness of stroke symptoms in stroke patients or at-risk populations?. ### Response: population-based studies.


Instruction: What have several population-based studies shown that knowl-edge and awareness are somewhat higher in women than men?

Output: stroke warning signs and symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have several population-based studies shown that knowl-edge and awareness are somewhat higher in women than men?. ### Response: stroke warning signs and symptoms.