Instruction: Where were studies published in languages other than English not reviewed?

Output: Studies published in languages other than English were not reviewed.  The health economic search strategies are included in appendix  N

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where were studies published in languages other than English not reviewed?. ### Response: Studies published in languages other than English were not reviewed.  The health economic search strategies are included in appendix  N.


Instruction: When was the general heart failure economic search updated?

Output: 6 December 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the general heart failure economic search updated?. ### Response: 6 December 2017.


Instruction: When was the economic search updated?

Output: 6 December 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the economic search updated?. ### Response: 6 December 2017.


Instruction: When were no papers published after the date of the update?

Output: 6 December 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were no papers published after the date of the update?. ### Response: 6 December 2017.


Instruction: What is associated with an increased risk of premature coronary and cerebrovascular atherosclerosis?

Output: HIV Infection and SIHDHIV infection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with an increased risk of premature coronary and cerebrovascular atherosclerosis?. ### Response: HIV Infection and SIHDHIV infection.


Instruction: What is often the initialmanifestation?

Output: AMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often the initialmanifestation?. ### Response: AMI.


Instruction: The etiology is likely multifactorial and related to both the underlying infection and what?

Output: antiretroviraltherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The etiology is likely multifactorial and related to both the underlying infection and what?. ### Response: antiretroviraltherapy.


Instruction: What appears to promote proliferation of smooth muscle cells and elastin leading to luminal obstruction?

Output: antiretroviraltherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What appears to promote proliferation of smooth muscle cells and elastin leading to luminal obstruction?. ### Response: antiretroviraltherapy.


Instruction: What is poor correlation between CD4 cellcounts and severity of CAD?

Output: luminal obstruc-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is poor correlation between CD4 cellcounts and severity of CAD?. ### Response: luminal obstruc-tion.


Instruction: What has been epidemiologically linked to dyslipidemia and insulinresistance?

Output: protease inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been epidemiologically linked to dyslipidemia and insulinresistance?. ### Response: protease inhibitors.


Instruction: What are the protease inhibitors amprenavir/fosam-prenavir with or without ritonavir and lopinavir?

Output: AMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the protease inhibitors amprenavir/fosam-prenavir with or without ritonavir and lopinavir?. ### Response: AMI.


Instruction: What are the two nucleoside reverse-transcriptase inhibitors associated with?

Output: risk ofAMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two nucleoside reverse-transcriptase inhibitors associated with?. ### Response: risk ofAMI.


Instruction: What are two other agents that are not associated with an increased risk of IHD?

Output: nonnucleoside reverse-transcriptase inhibitors (nevirapine and efavirenz), entry in-hibitors, and integrase inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two other agents that are not associated with an increased risk of IHD?. ### Response: nonnucleoside reverse-transcriptase inhibitors (nevirapine and efavirenz), entry in-hibitors, and integrase inhibitors.


Instruction: What is the absolute increase in incidence of AMI?

Output: relatively low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the absolute increase in incidence of AMI?. ### Response: relatively low.


Instruction: What does not appear to be increased?

Output: overall mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not appear to be increased?. ### Response: overall mortality.


Instruction: Who should be assessed for cardiovascular risk factors and moni-tored for signs and symptoms of IHD?

Output: patients receiving highly active antiretroviral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should be assessed for cardiovascular risk factors and moni-tored for signs and symptoms of IHD?. ### Response: patients receiving highly active antiretroviral.


Instruction: What should patients with hypercholesterolemia be managed in a fashion similar to?

Output: other patients atrisk for IHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with hypercholesterolemia be managed in a fashion similar to?. ### Response: other patients atrisk for IHD.


Instruction: What should be managed in a fashion similar to other patients at risk for IHD?

Output: Patients with hypercholesterolemi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be managed in a fashion similar to other patients at risk for IHD?. ### Response: Patients with hypercholesterolemi.


Instruction: What represents a less well-studied issue in SIHD? What is increased inflammation in the coronary arterywalls with increased frequency of vulnerable plaques?

Output: Autoimmune DisordersConnective tissue disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What represents a less well-studied issue in SIHD? What is increased inflammation in the coronary arterywalls with increased frequency of vulnerable plaques?. ### Response: Autoimmune DisordersConnective tissue disease.


Instruction: What is the adjusted rate of SIHD in systemic lupus erythematosis /H1135050-fold higher than in patients without SIHD?

Output: 1206,1207

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the adjusted rate of SIHD in systemic lupus erythematosis /H1135050-fold higher than in patients without SIHD?. ### Response: 1206,1207.


Instruction: A younger population is more frequently affected in what?

Output: insystemic lupus erythematosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A younger population is more frequently affected in what?. ### Response: insystemic lupus erythematosis.


Instruction: What is a common complication in connective tissue disease?

Output: coronary artery spasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common complication in connective tissue disease?. ### Response: coronary artery spasm.


Instruction: What is low socioeconomic status highly associated with?

Output: the riskof cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low socioeconomic status highly associated with?. ### Response: the riskof cardiovascular disease.


Instruction: What is the title of the 2014 AHA/ACC NSTE-ACS Guideline?

Output: e419

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the 2014 AHA/ACC NSTE-ACS Guideline?. ### Response: e419.


Instruction: Who is the Content Reviewer-AACCUniversity of Maryland School of Medicine?

Output: –Professor of Pathology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Content Reviewer-AACCUniversity of Maryland School of Medicine?. ### Response: –Professor of Pathology.


Instruction: Where is Robert H. Christenson from?

Output: Amsterdam

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Robert H. Christenson from?. ### Response: Amsterdam.


Instruction: Who is the President of AACC?

Output: The Medicines Company

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the President of AACC?. ### Response: The Medicines Company.


Instruction: What is the name of Roche Diagnostics?

Output: University of Maryland School of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of Roche Diagnostics?. ### Response: University of Maryland School of Medicine.


Instruction: Who is on the Editorial Board of ACC Cardiovascular Imaging Section Leadership?

Output: Marco A. Costa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is on the Editorial Board of ACC Cardiovascular Imaging Section Leadership?. ### Response: Marco A. Costa.


Instruction: Who is a content reviewer for the ACC Cardiovascular Imaging Section Leadership Council?

Output: Linda D. Gillam

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a content reviewer for the ACC Cardiovascular Imaging Section Leadership Council?. ### Response: Linda D. Gillam.


Instruction: What is the name of the organization that reviews the content for the Cardiovascular imaging section?

Output: Leadership Council

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that reviews the content for the Cardiovascular imaging section?. ### Response: Leadership Council.


Instruction: Who is the author of the article?

Output: Robert H. Christenson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the article?. ### Response: Robert H. Christenson.


Instruction: Who is a content reviewer for the ACC Prevention of Cardiovascular Disease Committee?

Output: Prakash C. Deedwania

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a content reviewer for the ACC Prevention of Cardiovascular Disease Committee?. ### Response: Prakash C. Deedwania.


Instruction: Who is the Director of Coronary Care Unit and Cardiology Fellowship at UT Southwestern Medical School?

Output: James A. de Lemos

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of Coronary Care Unit and Cardiology Fellowship at UT Southwestern Medical School?. ### Response: James A. de Lemos.


Instruction: Who is a professor of medicine at the University of California Davis?

Output: Burl R. Don Content

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a professor of medicine at the University of California Davis?. ### Response: Burl R. Don Content.


Instruction: Who is the director of clinical nephrology?

Output: Burl R. Don Content

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the director of clinical nephrology?. ### Response: Burl R. Don Content.


Instruction: What department of anesthesiology is the professor of?

Output: University of Pennsylvania

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What department of anesthesiology is the professor of?. ### Response: University of Pennsylvania.


Instruction: Who is a professor of Anesthesiology at the University of Pennsylvania?

Output: Lee A. Fleisher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a professor of Anesthesiology at the University of Pennsylvania?. ### Response: Lee A. Fleisher.


Instruction: Who is the professor of Cardiology at the Morristown Medical Center?

Output: Linda D. Gillam

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of Cardiology at the Morristown Medical Center?. ### Response: Linda D. Gillam.


Instruction: What is the title of the Senior Medical Officer at the Centers for Disease Control and Prevention?

Output: Division for Heart Disease and Stroke Prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the Senior Medical Officer at the Centers for Disease Control and Prevention?. ### Response: Division for Heart Disease and Stroke Prevention.


Instruction: Who is the Vice Chair of Cardiovascular Medicine at Morristown Medical Center?

Output: Linda D. Gillam

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Chair of Cardiovascular Medicine at Morristown Medical Center?. ### Response: Linda D. Gillam.


Instruction: What is the name of the person who is a member of the ACC Cardiovascular Imaging Section Leadership Council?

Output: Marco A. Costa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who is a member of the ACC Cardiovascular Imaging Section Leadership Council?. ### Response: Marco A. Costa.


Instruction: On what date will the ahajournals.org publication be available?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date will the ahajournals.org publication be available?. ### Response: April 28, 2023.


Instruction: How long should the patient sit in a chair with feet flat on floor and back supported before recording the first reading?

Output: 3 – 5 minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should the patient sit in a chair with feet flat on floor and back supported before recording the first reading?. ### Response: 3 – 5 minutes.


Instruction: What do patients avoid for 30 minutes before measurement?

Output: caffeine, exercise, and smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients avoid for 30 minutes before measurement?. ### Response: caffeine, exercise, and smoking.


Instruction: What should the patient do during rest period or the measurement?

Output: talk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the patient do during rest period or the measurement?. ### Response: talk.


Instruction: What does not fulfill the criteria for sitting on an examination table?

Output: Use proper technique

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not fulfill the criteria for sitting on an examination table?. ### Response: Use proper technique.


Instruction: What type of technique is preferred?

Output: attended or unattended, fully AOBP measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of technique is preferred?. ### Response: attended or unattended, fully AOBP measurement.


Instruction: What is a validated upper - arm cuff measurement device that has been calibrated?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a validated upper - arm cuff measurement device that has been calibrated?. ### Response: •.


Instruction: What is the correct size of the cuff?

Output: 75 – 100% of the upper arm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the correct size of the cuff?. ### Response: 75 – 100% of the upper arm.


Instruction: What percentage of the upper arm is encircled by the bladder?

Output: 75 – 100%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the upper arm is encircled by the bladder?. ### Response: 75 – 100%.


Instruction: At the first visit, record blood pressure in both arms.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At the first visit, record blood pressure in both arms.. ### Response: •.


Instruction: What gives the higher reading for subsequent readings?

Output: arm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What gives the higher reading for subsequent readings?. ### Response: arm.


Instruction: How long does it take to separate repeated measurements by 30 seconds?

Output: ≥30 secondsProperly document accurate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to separate repeated measurements by 30 seconds?. ### Response: ≥30 secondsProperly document accurate.


Instruction: What should be used for initial documentation of the patient’s blood pressure?

Output: an average of the visit readings from ≥2 occasions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used for initial documentation of the patient’s blood pressure?. ### Response: an average of the visit readings from ≥2 occasions.


Instruction: What should patients be given for their SBP/DBP readings?

Output: both verbally and in writing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients be given for their SBP/DBP readings?. ### Response: both verbally and in writing.


Instruction: What should patients be able to do to help them understand their blood pressure readings?

Output: interpret the results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients be able to do to help them understand their blood pressure readings?. ### Response: interpret the results.


Instruction: What are the two parts of the CPG that provide more information about blood pressure measurements?

Output: Appendix G and Appendix H

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two parts of the CPG that provide more information about blood pressure measurements?. ### Response: Appendix G and Appendix H.


Instruction: What is the abbreviation for A1c?

Output: glycated hemoglobin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the abbreviation for A1c?. ### Response: glycated hemoglobin.


Instruction: What is ABPM?

Output: ambulatory blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ABPM?. ### Response: ambulatory blood pressure monitoring.


Instruction: How is ARB measured?

Output: angiotensin II receptor blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is ARB measured?. ### Response: angiotensin II receptor blockers.


Instruction: What is the acronym for angiotensin II receptor blockers?

Output: ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for angiotensin II receptor blockers?. ### Response: ARB.


Instruction: What is atrioventricular?

Output: AV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atrioventricular?. ### Response: AV.


Instruction: What is DBP?

Output: diastolic blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DBP?. ### Response: diastolic blood pressure.


Instruction: What does DHP stand for?

Output: dihydropyridine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does DHP stand for?. ### Response: dihydropyridine.


Instruction: Where is DHP located?

Output: DoD  : Department of Defense

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is DHP located?. ### Response: DoD  : Department of Defense.


Instruction: What is left ventricular hypertrophy?

Output: LVH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is left ventricular hypertrophy?. ### Response: LVH.


Instruction: What is myocardial infarction?

Output: MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is myocardial infarction?. ### Response: MI.


Instruction: What is AFrecurrence often called?

Output: asymptomatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AFrecurrence often called?. ### Response: asymptomatic.


Instruction: What should patients be anticoagulated according to?

Output: CHA 2DS2-VAScthromboembolic risk pro ﬁle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients be anticoagulated according to?. ### Response: CHA 2DS2-VAScthromboembolic risk pro ﬁle.


Instruction: What is a weakrecommendation, low quality evidence?

Output: rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a weakrecommendation, low quality evidence?. ### Response: rivaroxaban.


Instruction: What can be performed in patients with AF?

Output: catheter ablation ofAF or implantation of cardiac electronic implantabledevices is planned, we suggest performing theprocedure on uninterrupted VKA (within the INRtherapeutic range), dabigatran or rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be performed in patients with AF?. ### Response: catheter ablation ofAF or implantation of cardiac electronic implantabledevices is planned, we suggest performing theprocedure on uninterrupted VKA (within the INRtherapeutic range), dabigatran or rivaroxaban.


Instruction: What should be based on the patient's CHA 2DS2-VAScthromboembolic risk pro file?

Output: long-term anticoagulations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be based on the patient's CHA 2DS2-VAScthromboembolic risk pro file?. ### Response: long-term anticoagulations.


Instruction: What is a weak recommendation, low quality evidence?

Output: dabigatran or rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a weak recommendation, low quality evidence?. ### Response: dabigatran or rivaroxaban.


Instruction: What is the risk of early recurrence in AF-associated acute ischemic stroke?

Output: high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of early recurrence in AF-associated acute ischemic stroke?. ### Response: high.


Instruction: What is another term for Cerebrovascular DiseaseAF Patients Presenting With an Acute IschemicStroke?

Output: TIA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for Cerebrovascular DiseaseAF Patients Presenting With an Acute IschemicStroke?. ### Response: TIA.


Instruction: What is the recurrence risk per day in the first 7 to 14 days?

Output: between 0.4% and 1.3%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recurrence risk per day in the first 7 to 14 days?. ### Response: between 0.4% and 1.3%.


Instruction: What are more often disabling or fatal than other types of strokes?

Output: AF-related ischemic strokes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are more often disabling or fatal than other types of strokes?. ### Response: AF-related ischemic strokes.


Instruction: Why is preventing earlyrecurring a key clinical challenge?

Output: moreoften disabling or fatal than other types, with longerhospital stays and higher costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is preventing earlyrecurring a key clinical challenge?. ### Response: moreoften disabling or fatal than other types, with longerhospital stays and higher costs.


Instruction: The safety and bene fit of OAC are what?

Output: notbeen established

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The safety and bene fit of OAC are what?. ### Response: notbeen established.


Instruction: The safety and bene fit of OAC in acute stroke have not been established what?

Output: Current guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The safety and bene fit of OAC in acute stroke have not been established what?. ### Response: Current guidelines.


Instruction: Early anticoagulation might increase the risk of symptomatic ICH including hemorrhagic transformation of the infarct?

Output: leading toclinical uncertainty about when to start anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Early anticoagulation might increase the risk of symptomatic ICH including hemorrhagic transformation of the infarct?. ### Response: leading toclinical uncertainty about when to start anticoagulation.


Instruction: What is the risk of recurrent ischemicstroke?

Output: 8% to 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of recurrent ischemicstroke?. ### Response: 8% to 10%.


Instruction: What risk is there of symptomatic ICH within 90 days of AF-related ischemia?

Output: 2% to 4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What risk is there of symptomatic ICH within 90 days of AF-related ischemia?. ### Response: 2% to 4%.


Instruction: Current guidelines do not provide recommendations on what?

Output: the timing of OAC afteracute AF-related stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Current guidelines do not provide recommendations on what?. ### Response: the timing of OAC afteracute AF-related stroke.


Instruction: What does not provide recommendations on the timing of OAC afteracute AF-related stroke?

Output: Current guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not provide recommendations on the timing of OAC afteracute AF-related stroke?. ### Response: Current guidelines.


Instruction: What do US guidelines suggest?

Output: thatTABLE 9 ]

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do US guidelines suggest?. ### Response: thatTABLE 9 ].


Instruction: What is the difference between interrupted and warfarin?

Output: low-molecular weight bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between interrupted and warfarin?. ### Response: low-molecular weight bridging.


Instruction: What is a difference between uninterrupted and interrupted?

Output: Uninterrupted warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a difference between uninterrupted and interrupted?. ### Response: Uninterrupted warfarin.


Instruction: How much difference is there in the incidence of major bleeding?

Output: 0.4%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much difference is there in the incidence of major bleeding?. ### Response: 0.4%).


Instruction: What percentage of statin treatment groups had major cardiovascular events in 3.8 years?

Output: 8.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of statin treatment groups had major cardiovascular events in 3.8 years?. ### Response: 8.5%.


Instruction: Strong general evidence indicates that the benefit from statin therapy is related to both global risk and intensity of treatment?

Output: S4.3-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Strong general evidence indicates that the benefit from statin therapy is related to both global risk and intensity of treatment?. ### Response: S4.3-3.


Instruction: High-intensity statin therapy has been carried out in cohorts of whom?

Output: >75 years of age with diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: High-intensity statin therapy has been carried out in cohorts of whom?. ### Response: >75 years of age with diabetes mellitus.


Instruction: Patients with diabetes mellitus have a higher trajectory of what?

Output: lifetime risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with diabetes mellitus have a higher trajectory of what?. ### Response: lifetime risk.


Instruction: High-intensity statin therapy is preferred in patients with diabetes mellitus as they age or develop what?

Output: risk modifiers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: High-intensity statin therapy is preferred in patients with diabetes mellitus as they age or develop what?. ### Response: risk modifiers.


Instruction: ASCVD risk increases incrementally with what type of diabetes?

Output: age in diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ASCVD risk increases incrementally with what type of diabetes?. ### Response: age in diabetes mellitus.


Instruction: In one long-term cohort study, incident rates of MI averaged what per year?

Output: 25.6 per 1000 person-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In one long-term cohort study, incident rates of MI averaged what per year?. ### Response: 25.6 per 1000 person-years.


Instruction: How many incidents of MI were there per 1000 person-years?

Output: 25.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many incidents of MI were there per 1000 person-years?. ### Response: 25.6.


Instruction: What was the 10-year fatal CVD risk in those >75 years old?

Output: 70% in men and 40% in women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 10-year fatal CVD risk in those >75 years old?. ### Response: 70% in men and 40% in women.


Instruction: What percentage of women are statin trials?

Output: 40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of women are statin trials?. ### Response: 40%.


Instruction: What is JUPITER?

Output: Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is JUPITER?. ### Response: Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin.


Instruction: Which trials showed similar benefits in ASCVD?

Output: JUPITER (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) and HOPE-3 (Heart Outcomes Prevention Evaluation)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which trials showed similar benefits in ASCVD?. ### Response: JUPITER (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) and HOPE-3 (Heart Outcomes Prevention Evaluation).


Instruction: What is the acronym for Heart Outcomes Prevention Evaluation?

Output: HOPE-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Heart Outcomes Prevention Evaluation?. ### Response: HOPE-3.


Instruction: What type of patients were included in the study?

Output: few patients with diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients were included in the study?. ### Response: few patients with diabetes mellitus.


Instruction: How did the study support the continued use of statin therapy?

Output: it does support the continuation of moderate- or high-intensity statin therapy for primary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the study support the continued use of statin therapy?. ### Response: it does support the continuation of moderate- or high-intensity statin therapy for primary prevention.


Instruction: What percentage of the population with diabetes mellitus are treated for primary prevention?

Output: 21%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the population with diabetes mellitus are treated for primary prevention?. ### Response: 21%.


Instruction: What may be off-set by limited life span or increased susceptibility to adverse events?

Output: the benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be off-set by limited life span or increased susceptibility to adverse events?. ### Response: the benefit.


Instruction: What type of risk enhancers are independent of other risk factors in diabetes Mellitus?

Output: Diabetes-Specific

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of risk enhancers are independent of other risk factors in diabetes Mellitus?. ### Response: Diabetes-Specific.


Instruction: How long does it take for type 2 diabetes mellitus to develop albuminuria?

Output: ≥10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for type 2 diabetes mellitus to develop albuminuria?. ### Response: ≥10 years.


Instruction: What is type 1 diabetes mellitus?

Output: S4.3-6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is type 1 diabetes mellitus?. ### Response: S4.3-6.


Instruction: What is the estimated glomerular filtration rate?

Output: eGFR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the estimated glomerular filtration rate?. ### Response: eGFR.


Instruction: What is a recent trend in the treatment of spontaneous intracerebral hemorrhage?

Output: analysis of a nationwide inpatient database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a recent trend in the treatment of spontaneous intracerebral hemorrhage?. ### Response: analysis of a nationwide inpatient database.


Instruction: What is the name of the study that analyzed a nationwide inpatient database?

Output: STROKEAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that analyzed a nationwide inpatient database?. ### Response: STROKEAHA.


Instruction: Incidence of seizures in the acute phase of stroke: a population-based study. Epilepsia. 2008;49:974–981. doi: 10.1016/j.1528-1167.2007.01513.x?

Output: 164

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Incidence of seizures in the acute phase of stroke: a population-based study. Epilepsia. 2008;49:974–981. doi: 10.1016/j.1528-1167.2007.01513.x?. ### Response: 164.


Instruction: What did Batjer HH say about anticonvulsant use and outcomes after intra-cerebral hemorrhage?

Output: poor outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Batjer HH say about anticonvulsant use and outcomes after intra-cerebral hemorrhage?. ### Response: poor outcome.


Instruction: What was the name of the study that found antiepileptic treatment and mortality?

Output: Neurocrit Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that found antiepileptic treatment and mortality?. ### Response: Neurocrit Care.


Instruction: What is the name of the retrospective study of intrace-rebral hemorrhage?

Output: Neurocrit Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the retrospective study of intrace-rebral hemorrhage?. ### Response: Neurocrit Care.


Instruction: What does antiepileptic treatment and mortality do?

Output: Confounding by indication in retrospective studies of intrace-rebral hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does antiepileptic treatment and mortality do?. ### Response: Confounding by indication in retrospective studies of intrace-rebral hemorrhage.


Instruction: Who is the CHANT investigator?

Output: Messé SR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the CHANT investigator?. ### Response: Messé SR.


Instruction: How is prophylactic drug use associated with poor outcome?

Output: associ-ated with poor outcome following ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is prophylactic drug use associated with poor outcome?. ### Response: associ-ated with poor outcome following ICH.


Instruction: What are post intracerebral hemorrhage seizures prevented by?

Output: anti-epileptic treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are post intracerebral hemorrhage seizures prevented by?. ### Response: anti-epileptic treatment.


Instruction: What is the doi: 10.1016/j.eplepsyres.2011.04.002?

Output: :227–231

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1016/j.eplepsyres.2011.04.002?. ### Response: :227–231.


Instruction: What is the name of the long-term follow-up study of post-stroke epilepsy in young adults?

Output: PLoS One

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the long-term follow-up study of post-stroke epilepsy in young adults?. ### Response: PLoS One.


Instruction: What year was the J Neurol Neurosurg Psychiatry published?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the J Neurol Neurosurg Psychiatry published?. ### Response: 1989.


Instruction: What is NXY-059 used for in acute intracerebral hemorrhage?

Output: Safety and tolerability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NXY-059 used for in acute intracerebral hemorrhage?. ### Response: Safety and tolerability.


Instruction: What is the name of the trial that evaluated safety and tolerability?

Output: CHANT Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that evaluated safety and tolerability?. ### Response: CHANT Trial.


Instruction: When did the CHANT Trial begin?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the CHANT Trial begin?. ### Response: 2007.


Instruction: What is the name of the 2007 trial that evaluated oral feeding in patients with intracerebral hem-orrhage?

Output: CHANT Trial Investigators. Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2007 trial that evaluated oral feeding in patients with intracerebral hem-orrhage?. ### Response: CHANT Trial Investigators. Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial.


Instruction: What is a retrospective cohort study?

Output: Early inter -vention to promote oral feeding in patients with intracerebral hem-orrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a retrospective cohort study?. ### Response: Early inter -vention to promote oral feeding in patients with intracerebral hem-orrhage.


Instruction: What is the name of the organization that investigates the prevention of dysphagia?

Output: CHANT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that investigates the prevention of dysphagia?. ### Response: CHANT.


Instruction: What is one of the factors that predict the outcome of percutaneous endoscopic gastrostomy in spontaneous intracranial hemorrhage?

Output: antiepileptic treatment and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the factors that predict the outcome of percutaneous endoscopic gastrostomy in spontaneous intracranial hemorrhage?. ### Response: antiepileptic treatment and mortality.


Instruction: When did Eur Neurol issue 65:32–38?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Neurol issue 65:32–38?. ### Response: 2011.


Instruction: What does the Stroke Practice Improvement Network Investigators prevent?

Output: pneumonia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Stroke Practice Improvement Network Investigators prevent?. ### Response: pneumonia.


Instruction: What prevents pneumonia?

Output: Formal dysphagia screen-ing protocols

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What prevents pneumonia?. ### Response: Formal dysphagia screen-ing protocols.


Instruction: When was the last time a person had a stroke?

Output: 109.559948

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a person had a stroke?. ### Response: 109.559948.


Instruction: What is the name of the 2019 ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary?

Output: Arnett

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2019 ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary?. ### Response: Arnett.


Instruction: How long is the time horizon to the clinical mani-festation of disease?

Output: —many decades in the young

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the time horizon to the clinical mani-festation of disease?. ### Response: —many decades in the young.


Instruction: How many decades in the young is it difficult to assess long-term effectiveness?

Output: —many decades

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many decades in the young is it difficult to assess long-term effectiveness?. ### Response: —many decades.


Instruction: What is QALYs?

Output: quality-adjusted life-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is QALYs?. ### Response: quality-adjusted life-years.


Instruction: What are QALYs?

Output: quality-adjusted life-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are QALYs?. ### Response: quality-adjusted life-years.


Instruction: What is the principle that places relative emphasis on current costs and benefits while deemphasizing downstream cost and benefits?

Output: discounting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the principle that places relative emphasis on current costs and benefits while deemphasizing downstream cost and benefits?. ### Response: discounting.


Instruction: What are disadvantages for prevention because costs of-ten accrue in the present while the benefit may only be fully realized long into the future?

Output: the principle of discounting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are disadvantages for prevention because costs of-ten accrue in the present while the benefit may only be fully realized long into the future?. ### Response: the principle of discounting.


Instruction: Prior AHA statements have highlighted what?

Output: public policies, community efforts, and pharmacological interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prior AHA statements have highlighted what?. ### Response: public policies, community efforts, and pharmacological interventions.


Instruction: What are likely to be cost-effective and at times cost-saving prevention tac-tics compared with common benchmarks?

Output: public policies, community efforts, and pharmacological interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are likely to be cost-effective and at times cost-saving prevention tac-tics compared with common benchmarks?. ### Response: public policies, community efforts, and pharmacological interventions.


Instruction: Antihypertensive therapyS5-3-S5-6 and statin therapyS5-7-S5,-9 particularly with low-cost generic drug formulations are high-value inter ventions across a wide spectrum of risk and age strata?

Output: high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antihypertensive therapyS5-3-S5-6 and statin therapyS5-7-S5,-9 particularly with low-cost generic drug formulations are high-value inter ventions across a wide spectrum of risk and age strata?. ### Response: high.


Instruction: What is one of several considerations in medical decision-making and resource allocation?

Output: The incorporation of the value category into clinical practice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of several considerations in medical decision-making and resource allocation?. ### Response: The incorporation of the value category into clinical practice guidelines.


Instruction: What must clini-cians, researchers, and policymakers place in the proper context?

Output: cost-effective analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must clini-cians, researchers, and policymakers place in the proper context?. ### Response: cost-effective analyses.


Instruction: What is needed to fully characterize the full spectrum of benefits produced by the preven-tion approach?

Output: Further research and methodological advances

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to fully characterize the full spectrum of benefits produced by the preven-tion approach?. ### Response: Further research and methodological advances.


Instruction: What is more consequential to cost-effectiveness as-sessments?

Output: uncertainty about outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more consequential to cost-effectiveness as-sessments?. ### Response: uncertainty about outcome.


Instruction: What does the preven-tion approach make more consequential to clinical practice?

Output: cost-effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the preven-tion approach make more consequential to clinical practice?. ### Response: cost-effectiveness.


Instruction: Most ASCVD events are avoidable through what?

Output: primordial prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most ASCVD events are avoidable through what?. ### Response: primordial prevention.


Instruction: Tobacco avoidance is critically important for what kind of prevention?

Output: ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tobacco avoidance is critically important for what kind of prevention?. ### Response: ASCVD.


Instruction: What should all adults strive to do most days of the Table 8?

Output: regular brisk physical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all adults strive to do most days of the Table 8?. ### Response: regular brisk physical activity.


Instruction: What are the highlights of Recommended Behavioral and Pharmacotherapy Tobacco Treatment Modalities?

Output: *Timing of Behavioral Interventions†<3 min of tobacco status assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the highlights of Recommended Behavioral and Pharmacotherapy Tobacco Treatment Modalities?. ### Response: *Timing of Behavioral Interventions†<3 min of tobacco status assessment.


Instruction: What is NICE 2018?

Output: Chronic Heart Failure  Monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: Chronic Heart Failure  Monitoring.


Instruction: What did the committee not feel they could do?

Output: confident that the usual care prescribed in the studies was representative of current UK practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee not feel they could do?. ### Response: confident that the usual care prescribed in the studies was representative of current UK practice.


Instruction: What did the committee not feel was representative of current UK practice?

Output: the usual care prescribed in the studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee not feel was representative of current UK practice?. ### Response: the usual care prescribed in the studies.


Instruction: What did clinical evidence suggest about STS in people with chronic heart failure?

Output: there was a clinically important reduction in mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did clinical evidence suggest about STS in people with chronic heart failure?. ### Response: there was a clinically important reduction in mortality.


Instruction: What did STS have a clinically important effect on?

Output: reduction in hospitalisations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did STS have a clinically important effect on?. ### Response: reduction in hospitalisations.


Instruction: What was the effect of STS on hospitalisations in people with STS?

Output: There was no cli nical effect of STS on hospitalisations in people who had recently been admitted. While in people recruited within the community, STS showed a clinically important reduction in hospitalisations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of STS on hospitalisations in people with STS?. ### Response: There was no cli nical effect of STS on hospitalisations in people who had recently been admitted. While in people recruited within the community, STS showed a clinically important reduction in hospitalisations.


Instruction: What did STS show a clinically important reduction in in people recruited within the community?

Output: hospitalisations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did STS show a clinically important reduction in in people recruited within the community?. ### Response: hospitalisations.


Instruction: What made it difficult to interpret the effectiveness of STS overall?

Output: The differences between the interventions used in each stud y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What made it difficult to interpret the effectiveness of STS overall?. ### Response: The differences between the interventions used in each stud y.


Instruction: What was a significant degree of variability in the intensity of STS?

Output: daily calls compared to monthly calls

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a significant degree of variability in the intensity of STS?. ### Response: daily calls compared to monthly calls.


Instruction: What was the focus of the STS, i.e.?

Output: clinical monitoring of heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the STS, i.e.?. ### Response: clinical monitoring of heart failure.


Instruction: What was the difference between symptoms with clinical support provided and self-management education?

Output: might not have the same effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between symptoms with clinical support provided and self-management education?. ### Response: might not have the same effect.


Instruction: What was variable depending on the measurement scale used?

Output: The effect of STS on QoL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was variable depending on the measurement scale used?. ### Response: The effect of STS on QoL.


Instruction: What made it difficult for the committee to interpret the true clinical effect?

Output: wide confidence intervals surrounding the effect estimate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What made it difficult for the committee to interpret the true clinical effect?. ### Response: wide confidence intervals surrounding the effect estimate.


Instruction: The committee agreed that the impact of STS on QoL would be variable depending on what?

Output: the intensity and focus of the intervention and the motivation of the in dividual

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee agreed that the impact of STS on QoL would be variable depending on what?. ### Response: the intensity and focus of the intervention and the motivation of the in dividual.


Instruction: What would be variable depending on the person's willingness to engage with the intervention and the specific focus of the STS?

Output: the impact of STS on QoL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be variable depending on the person's willingness to engage with the intervention and the specific focus of the STS?. ### Response: the impact of STS on QoL.


Instruction: What might not have the same effect as an intervention aimed at providing education and support?

Output: STS that mainly focused on highlighting worrying symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might not have the same effect as an intervention aimed at providing education and support?. ### Response: STS that mainly focused on highlighting worrying symptoms.


Instruction: How many studies reported patient adherence to STS?

Output: one

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies reported patient adherence to STS?. ### Response: one.


Instruction: What did the committee agree that in practice adherence would be variable depending on?

Output: the intensity and focus of the intervention and the motivation of the in dividual

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee agree that in practice adherence would be variable depending on?. ### Response: the intensity and focus of the intervention and the motivation of the in dividual.


Instruction: The committee discussed the potential harms associated with what?

Output: STS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee discussed the potential harms associated with what?. ### Response: STS.


Instruction: What did elderly patients find alarming when their phone rang, had difficulty using or did not like using their phone?

Output: anxiety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did elderly patients find alarming when their phone rang, had difficulty using or did not like using their phone?. ### Response: anxiety.


Instruction: What caused people to have a significant degree of anxiety?

Output: their phone rang, had difficulty using  or did not like using their phone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What caused people to have a significant degree of anxiety?. ### Response: their phone rang, had difficulty using  or did not like using their phone.


Instruction: Monitoring the signs and symptoms of heart failure on a regular basis may provoke anxiety in some people?

Output: diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Monitoring the signs and symptoms of heart failure on a regular basis may provoke anxiety in some people?. ### Response: diagnosis.


Instruction: What was distress associated with having attention drawn to their diagnosis?

Output: Monitoring the signs and symptoms of heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was distress associated with having attention drawn to their diagnosis?. ### Response: Monitoring the signs and symptoms of heart failure.


Instruction: What did the committee acknowledge was a relevant form of providing?

Output: ad hoc telephone appointments and calls to the appropriate clinicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee acknowledge was a relevant form of providing?. ### Response: ad hoc telephone appointments and calls to the appropriate clinicians.


Instruction: What was visualized?

Output: bus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was visualized?. ### Response: bus.


Instruction: What will lengthen the diastolic fill-ing period and lower LA pressure in symptomatic MS patients?

Output: heart rate control with beta blockers, calcium channel blockers, or ivabradine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will lengthen the diastolic fill-ing period and lower LA pressure in symptomatic MS patients?. ### Response: heart rate control with beta blockers, calcium channel blockers, or ivabradine.


Instruction: What may use of heart rate control for patients with rheumatic MS in normal sinus rhythm in the absence of tachycardia result in?

Output: chronotropic incompetence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may use of heart rate control for patients with rheumatic MS in normal sinus rhythm in the absence of tachycardia result in?. ### Response: chronotropic incompetence.


Instruction: What may prevent an ad-equate cardiac output response to exercise?

Output: routine use of heart rate control for patients with rheumatic MS in normal sinus rhythm in the absence of tachycardia may result in chronotropic incompetence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may prevent an ad-equate cardiac output response to exercise?. ### Response: routine use of heart rate control for patients with rheumatic MS in normal sinus rhythm in the absence of tachycardia may result in chronotropic incompetence.


Instruction: Patients with AF and prior embolic events are at high risk of what?

Output: arterial embo-lization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with AF and prior embolic events are at high risk of what?. ### Response: arterial embo-lization.


Instruction: What is at high risk of arterial embolization when AF or LA thrombus is present?

Output: Patients with rheumatic MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is at high risk of arterial embolization when AF or LA thrombus is present?. ### Response: Patients with rheumatic MS.


Instruction: What will decrease the incidence of these events?

Output: Treatment with VKA anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will decrease the incidence of these events?. ### Response: Treatment with VKA anticoagulation.


Instruction: Patients with rheumatic MS in normal sinus rhythm on the basis of what?

Output: LA enlargement or spontaneous contrast on TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with rheumatic MS in normal sinus rhythm on the basis of what?. ### Response: LA enlargement or spontaneous contrast on TEE.


Instruction: Patients with very large left atria have more spontaneous echo-cardiographic contrast and lower LA appendage Doppler velocities than patients with what other condition?

Output: rheumatic MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with very large left atria have more spontaneous echo-cardiographic contrast and lower LA appendage Doppler velocities than patients with what other condition?. ### Response: rheumatic MS.


Instruction: What has been associated with a higher rate of embolic events?

Output: Patients with very large left atria have more spontaneous echo-cardiographic contrast and lower LA appendage Doppler velocities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been associated with a higher rate of embolic events?. ### Response: Patients with very large left atria have more spontaneous echo-cardiographic contrast and lower LA appendage Doppler velocities.


Instruction: No data directly link large left atria to embolic events?

Output: Patients with very large left atria have more spontaneous echo-cardiographic contrast and lower LA appendage Doppler velocities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No data directly link large left atria to embolic events?. ### Response: Patients with very large left atria have more spontaneous echo-cardiographic contrast and lower LA appendage Doppler velocities.


Instruction: Non-vitamin K oral anticoagulation has not been studied in what type of MS?

Output: rheumatic MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Non-vitamin K oral anticoagulation has not been studied in what type of MS?. ### Response: rheumatic MS.


Instruction: Patients with rheumatic MS were excluded from what?

Output: randomized AF trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with rheumatic MS were excluded from what?. ### Response: randomized AF trials.


Instruction: What is the risk of embo-lization with rheumatic valve disease compared with other causes of valve disease?

Output: higher risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of embo-lization with rheumatic valve disease compared with other causes of valve disease?. ### Response: higher risk.


Instruction: What muscle is affected in addition to the atrial muscle?

Output: rheumatic disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What muscle is affected in addition to the atrial muscle?. ### Response: rheumatic disease.


Instruction: In addition to blood flow stasis and thrombosis in the body of the atrium muscle, what is an increased risk of?

Output: embo-lization with rheumatic valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to blood flow stasis and thrombosis in the body of the atrium muscle, what is an increased risk of?. ### Response: embo-lization with rheumatic valve disease.


Instruction: What is the body of the LA called?

Output: LA appendage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the body of the LA called?. ### Response: LA appendage.


Instruction: What are patients with rheumatic MS prone to developing?

Output: atrial arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with rheumatic MS prone to developing?. ### Response: atrial arrhythmias.


Instruction: What may be associated with the acute development of AF?

Output: Significant detrimental hemodynamic consequences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with the acute development of AF?. ### Response: Significant detrimental hemodynamic consequences.


Instruction: What shortens the diastolic filling period and increases LA pressure?

Output: rapid ventricular response

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What shortens the diastolic filling period and increases LA pressure?. ### Response: rapid ventricular response.


Instruction: The treatment of acute AF consists of what?

Output: anticoagulation and control of the heart rate response with negative dromotropic agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The treatment of acute AF consists of what?. ### Response: anticoagulation and control of the heart rate response with negative dromotropic agents.


Instruction: What may be necessary to improve hemodynamics if the rate cannot be adequately controlled with medica-tions?

Output: cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be necessary to improve hemodynamics if the rate cannot be adequately controlled with medica-tions?. ### Response: cardioversion.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 25 of 134 Topic Sub-topic # Recommendation Strengtha Categoryb Pharmacological Treatment a. For Hypertension What type of diuretic do we recommend offering?

Output: thiazide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 25 of 134 Topic Sub-topic # Recommendation Strengtha Categoryb Pharmacological Treatment a. For Hypertension What type of diuretic do we recommend offering?. ### Response: thiazide.


Instruction: What type of diuretic is recommended as primary pharmacologic therapy for hypertension?

Output: thiazide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diuretic is recommended as primary pharmacologic therapy for hypertension?. ### Response: thiazide.


Instruction: What is an angiotensin II receptor blocker?

Output: enzyme inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an angiotensin II receptor blocker?. ### Response: enzyme inhibitor.


Instruction: What is another name for an angiotensin converting enzyme inhibitor?

Output: angiotensin II receptor blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for an angiotensin converting enzyme inhibitor?. ### Response: angiotensin II receptor blocker.


Instruction: What is a monotherapy for hypertensive patients 65 years and over?

Output: thiazide -type diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a monotherapy for hypertensive patients 65 years and over?. ### Response: thiazide -type diuretic.


Instruction: What type of diuretic is suggested for hypertensive patients 65 years and over?

Output: thiazide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diuretic is suggested for hypertensive patients 65 years and over?. ### Response: thiazide.


Instruction: What is thiazide -type diuretics for?

Output: reduction in composite cardiovascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is thiazide -type diuretics for?. ### Response: reduction in composite cardiovascular outcomes.


Instruction: How many drug classes together are recommended in the same patient?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drug classes together are recommended in the same patient?. ### Response: three.


Instruction: How many drug classes can be used in the same patient?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drug classes can be used in the same patient?. ### Response: three.


Instruction: What are angiotensin converting enzyme inhibitors?

Output: angiotensin II receptor blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are angiotensin converting enzyme inhibitors?. ### Response: angiotensin II receptor blocker.


Instruction: What is evidence to recommend for or against initiating combination therapy over initiating monotherapy with the sequential addition of another medication?

Output: against

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evidence to recommend for or against initiating combination therapy over initiating monotherapy with the sequential addition of another medication?. ### Response: against.


Instruction: What is the definition of patients with resistant hypertension?

Output: those who are not adequately controlled with maximally tolerated dose of triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of patients with resistant hypertension?. ### Response: those who are not adequately controlled with maximally tolerated dose of triple therapy.


Instruction: What are patients who are not adequately controlled with maximally tolerated dose of triple therapy defined as?

Output: resistant hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients who are not adequately controlled with maximally tolerated dose of triple therapy defined as?. ### Response: resistant hypertension.


Instruction: What do we suggest adding in those patients without contraindications?

Output: spironolactone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest adding in those patients without contraindications?. ### Response: spironolactone.


Instruction: What is spironolactone in those patients without contraindications?

Output: spironolactone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is spironolactone in those patients without contraindications?. ### Response: spironolactone.


Instruction: What is Weak for Reviewed, New-replaced?

Output: spironolactone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Weak for Reviewed, New-replaced?. ### Response: spironolactone.


Instruction: Chronic Heart Failure Advanced heart failure and paliative care  NICE 2018. All rights reserved. Subject to What?

Output: Notice of rights

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chronic Heart Failure Advanced heart failure and paliative care  NICE 2018. All rights reserved. Subject to What?. ### Response: Notice of rights.


Instruction: ISBN: 978-1-4731 -3093 -7 460 Study Risk tool Population Outcomes No of events (%) Study design between what years?

Output: 2002 and 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ISBN: 978-1-4731 -3093 -7 460 Study Risk tool Population Outcomes No of events (%) Study design between what years?. ### Response: 2002 and 2006.


Instruction: What was the study design between 2002 and 2006?

Output: Spinar 2016318 AHEAD tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the study design between 2002 and 2006?. ### Response: Spinar 2016318 AHEAD tool.


Instruction: What is the AHEAD tool?

Output: n=6315

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHEAD tool?. ### Response: n=6315.


Instruction: How old are people with acute heart failure?

Output: 77

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are people with acute heart failure?. ### Response: 77.


Instruction: What country has a multicentre population?

Output: Spain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What country has a multicentre population?. ### Response: Spain.


Instruction: What is the mortality rate at 1 year AUC 31.6%?

Output: 1995 deaths

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mortality rate at 1 year AUC 31.6%?. ### Response: 1995 deaths.


Instruction: How many deaths were there in 1995?

Output: 31.6%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths were there in 1995?. ### Response: 31.6%.


Instruction: What is the 2013 ACC/AHA guide-line on the assessment of cardiovascular risk?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 ACC/AHA guide-line on the assessment of cardiovascular risk?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: ACC/AHA guide-line on the assessment of cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: ACC/AHA guide-line on the assessment of cardiovascular risk.


Instruction: What is the name of the multi-ethnic study of atherosclerosis?

Output: MESA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-ethnic study of atherosclerosis?. ### Response: MESA.


Instruction: What does MESA stand for?

Output: Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MESA stand for?. ### Response: Multi-Ethnic Study of Atherosclerosis.


Instruction: How many people have a family history for coronary heart disease?

Output: 35

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people have a family history for coronary heart disease?. ### Response: 35.


Instruction: What is the association of coronary artery calcium in adults aged 32 to 64?

Output: coronary heart disease risk prediction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of coronary artery calcium in adults aged 32 to 64?. ### Response: coronary heart disease risk prediction.


Instruction: What was the multi-ethnic study of atherosclerosis?

Output: MESA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the multi-ethnic study of atherosclerosis?. ### Response: MESA.


Instruction: What is the association of coronary artery calcium in adults aged 32 to 46 years with incident coronary heart disease and death?

Output: S4.4.2-37

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of coronary artery calcium in adults aged 32 to 46 years with incident coronary heart disease and death?. ### Response: S4.4.2-37.


Instruction: JAMA Cardiol. 2017;2:391-9. S4.4.2-37.

Output: coronary artery calcium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: JAMA Cardiol. 2017;2:391-9. S4.4.2-37.. ### Response: coronary artery calcium.


Instruction: When did Data Brief. 2016;6:578-81.

Output: Data on coronary artery calcium score performance and cardiovascular risk reclassification across gender and ethnicities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Data Brief. 2016;6:578-81.. ### Response: Data on coronary artery calcium score performance and cardiovascular risk reclassification across gender and ethnicities.


Instruction: What is risk reclassification across gender and ethnicities?

Output: cardiovascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is risk reclassification across gender and ethnicities?. ### Response: cardiovascular.


Instruction: What is associated with initiation and continuation of pharmacological and lifestyle preventive therapies?

Output: The identification of calcified coronary plaque

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with initiation and continuation of pharmacological and lifestyle preventive therapies?. ### Response: The identification of calcified coronary plaque.


Instruction: What is the name of the meta-analysis?

Output: Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis?. ### Response: Multi-Ethnic Study of Atherosclerosis.


Instruction: What is ACC/AHA guidelines for statin treatment strategy in asymptomatic Korean adults?

Output: Assessment of coronary artery calcium scoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACC/AHA guidelines for statin treatment strategy in asymptomatic Korean adults?. ### Response: Assessment of coronary artery calcium scoring.


Instruction: How is the cost-effectiveness of coronary artery calcium scoring determined?

Output: according to the American College of Cardiology and American Heart Association cholesterol guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the cost-effectiveness of coronary artery calcium scoring determined?. ### Response: according to the American College of Cardiology and American Heart Association cholesterol guidelines.


Instruction: What is the cost-effectiveness of coronary artery calcium testing among statin candidates?

Output: Cost-effectiveness of coronary artery calcium testing among statin candidates according to the American College of Cardiology and American Heart Association cholesterol guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of coronary artery calcium testing among statin candidates?. ### Response: Cost-effectiveness of coronary artery calcium testing among statin candidates according to the American College of Cardiology and American Heart Association cholesterol guidelines.


Instruction: What are the American College of Cardiology and American Heart Association cholesterol guidelines?

Output: Cost-effectiveness of coronary artery calcium testing among statin candidates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the American College of Cardiology and American Heart Association cholesterol guidelines?. ### Response: Cost-effectiveness of coronary artery calcium testing among statin candidates.


Instruction: How does CAC score improve coronary and CV risk assessment?

Output: above statin indication by ESC and AHA/ACC primary prevention guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does CAC score improve coronary and CV risk assessment?. ### Response: above statin indication by ESC and AHA/ACC primary prevention guidelines.


Instruction: What is a meta-analysis of prevalence and prognostic implications of coronary artery calcification?

Output: pharmacological and lifestyle preventive therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of prevalence and prognostic implications of coronary artery calcification?. ### Response: pharmacological and lifestyle preventive therapies.


Instruction: What are ESC and AHA/ACC primary prevention guidelines?

Output: CAC score improves coronary and CV risk assessment above statin indication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ESC and AHA/ACC primary prevention guidelines?. ### Response: CAC score improves coronary and CV risk assessment above statin indication.


Instruction: What is the J Am Coll Cardiol Img. 2017;10:143-53?

Output: HA/ACC primary prevention guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol Img. 2017;10:143-53?. ### Response: HA/ACC primary prevention guidelines.


Instruction: How long does it take to predict coronary heart disease?

Output: 10-Year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to predict coronary heart disease?. ### Response: 10-Year.


Instruction: What is MESA?

Output: Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MESA?. ### Response: Multi-Ethnic Study of Atherosclerosis.


Instruction: What is DHS?

Output: Dallas Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DHS?. ### Response: Dallas Heart Study.


Instruction: How many people were enrolled in the HNR study?

Output: Heinz Nixdorf Recall) Study and the DHS (Dallas Heart Study) J Am Coll Cardiol. 2015;66:1643–53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the HNR study?. ### Response: Heinz Nixdorf Recall) Study and the DHS (Dallas Heart Study) J Am Coll Cardiol. 2015;66:1643–53.


Instruction: What is calcification associated with?

Output: initiation and continuation of pharmacological and lifestyle preventive therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is calcification associated with?. ### Response: initiation and continuation of pharmacological and lifestyle preventive therapies.


Instruction: What is the name of the journal that deals with cardiovascular events?

Output: JAMA Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that deals with cardiovascular events?. ### Response: JAMA Cardiol.


Instruction: When was the JAMA published?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 2016.


Instruction: What do patients with higher predischarge levels and patients who do not have a decrease in natriuretic peptide biomarker levels during hospitalization have worse outcomes?

Output: worse outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients with higher predischarge levels and patients who do not have a decrease in natriuretic peptide biomarker levels during hospitalization have worse outcomes?. ### Response: worse outcomes.


Instruction: What did natriuretic peptide biomarker reduction have better outcomes than?

Output: those without any changes or with a biomarker rise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did natriuretic peptide biomarker reduction have better outcomes than?. ### Response: those without any changes or with a biomarker rise.


Instruction: Targeting a certain threshold, value or relative change in these biomarkers during hospitalization may not be practical or safe for every patient?

Output: has not been tested in a prospective large-scale trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Targeting a certain threshold, value or relative change in these biomarkers during hospitalization may not be practical or safe for every patient?. ### Response: has not been tested in a prospective large-scale trial.


Instruction: What should be the focus of clinical assessment and adherence to GDMT?

Output: prognostic value of a predischarge value or relative changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the focus of clinical assessment and adherence to GDMT?. ### Response: prognostic value of a predischarge value or relative changes.


Instruction: The prognostic value of a predischarge value or relative changes does not imply the necessity for what during hospitalization?

Output: serial and repeated biomarker measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The prognostic value of a predischarge value or relative changes does not imply the necessity for what during hospitalization?. ### Response: serial and repeated biomarker measurements.


Instruction: What may be considered for additive risk stratification in patients with chronic HF?

Output: measurement of other clinically available tests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for additive risk stratification in patients with chronic HF?. ### Response: measurement of other clinically available tests.


Instruction: What has been combined into prognosis section?

Output: 2013 recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been combined into prognosis section?. ### Response: 2013 recommendations.


Instruction: What is predictive of hospitalization and death in patients with HF?

Output: Biomarkers of myocardial fibrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is predictive of hospitalization and death in patients with HF?. ### Response: Biomarkers of myocardial fibrosis.


Instruction: What is additive to natriuretic peptide biomarker levels in their prognostic value?

Output: Biomarkers of myocardial fibrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is additive to natriuretic peptide biomarker levels in their prognostic value?. ### Response: Biomarkers of myocardial fibrosis.


Instruction: What may ultimately prove to be more informative than single biomarkers?

Output: A combination of biomarkers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may ultimately prove to be more informative than single biomarkers?. ### Response: A combination of biomarkers.


Instruction: Where can you find a copy of the ahajournals.org recomendations?

Output: http://ahajournals.org by on May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find a copy of the ahajournals.org recomendations?. ### Response: http://ahajournals.org by on May 3, 2023.


Instruction: What are implantable cardioverter-defi-brillators for primary prevention of?

Output: sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implantable cardioverter-defi-brillators for primary prevention of?. ### Response: sudden cardiac death.


Instruction: How many randomized trials did Pun PH, Al-Khatib SM, Han JY, and Liu JY participate in?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized trials did Pun PH, Al-Khatib SM, Han JY, and Liu JY participate in?. ### Response: 3.


Instruction: What is the name of the meta-analysis of patient-level data from 3 trials?

Output: Implantable cardioverter-defi-brillators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of patient-level data from 3 trials?. ### Response: Implantable cardioverter-defi-brillators.


Instruction: What is the predominant mechanism of sudden cardiac death in patients with chronic kidney disease?

Output: Bradycardia and asystole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the predominant mechanism of sudden cardiac death in patients with chronic kidney disease?. ### Response: Bradycardia and asystole.


Instruction: Bradycardia and asystole are the predominant mechanisms of what type of death?

Output: sudden cardiac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bradycardia and asystole are the predominant mechanisms of what type of death?. ### Response: sudden cardiac.