Instruction: What is the grade of thrombolytic therapy that we recommend against?

Output: Grade 1B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the grade of thrombolytic therapy that we recommend against?. ### Response: Grade 1B.


Instruction: What type of therapy is recommended in patients with acute PE who have a lowbleeding risk?

Output: thrombolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is recommended in patients with acute PE who have a lowbleeding risk?. ### Response: thrombolytic therapy.


Instruction: In patients with PE and without hypotension who have severe symptoms, we suggest what?

Output: marked card

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with PE and without hypotension who have severe symptoms, we suggest what?. ### Response: marked card.


Instruction: What should patients with PE and without hypotension be closely monitored for?

Output: deterioration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with PE and without hypotension be closely monitored for?. ### Response: deterioration.


Instruction: What suggests that development of hypotension suggests?

Output: 318 Evidence-Based Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What suggests that development of hypotension suggests?. ### Response: 318 Evidence-Based Medicine.


Instruction: What has been attributed to a lack of uniformity inpulse sequences and the application of varying analyticmethods?

Output: angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been attributed to a lack of uniformity inpulse sequences and the application of varying analyticmethods?. ### Response: angiography.


Instruction: Recent improvements applying 32-channel 3.0-TCMR have shown comparable abilities to detect what?

Output: CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent improvements applying 32-channel 3.0-TCMR have shown comparable abilities to detect what?. ### Response: CAD.


Instruction: What is the natural history of IHD that spans multiple decades?

Output: Prognosis of IHD for Death or Nonfatal MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the natural history of IHD that spans multiple decades?. ### Response: Prognosis of IHD for Death or Nonfatal MI.


Instruction: What is asymptomatic, stable angina, accelerat-ing angina and ACS?

Output: ally defined phases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic, stable angina, accelerat-ing angina and ACS?. ### Response: ally defined phases.


Instruction: What is UA or AMI?

Output: ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is UA or AMI?. ### Response: ACS.


Instruction: The specific approach to assessing risk of subsequent adverseoutcomes varies according to the patient's clinical phase, even though there is no universally accepted approach for those with SIHD?

Output: futureresearch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The specific approach to assessing risk of subsequent adverseoutcomes varies according to the patient's clinical phase, even though there is no universally accepted approach for those with SIHD?. ### Response: futureresearch.


Instruction: What is a key area for future research?

Output: Thespecific approach to assessing risk of subsequent adverseoutcomes varies according to the patient’s clinical phase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key area for future research?. ### Response: Thespecific approach to assessing risk of subsequent adverseoutcomes varies according to the patient’s clinical phase.


Instruction: What is informed by the treatment goals of prolonging survival andoptimizing health status?

Output: The approach recommended in the present guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is informed by the treatment goals of prolonging survival andoptimizing health status?. ### Response: The approach recommended in the present guideline.


Instruction: The concept that the benefits of treatment are often proportional to the patient's underlyingrisk is based on what?

Output: treatment goals of prolonging survival andoptimizing health status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The concept that the benefits of treatment are often proportional to the patient's underlyingrisk is based on what?. ### Response: treatment goals of prolonging survival andoptimizing health status.


Instruction: What is the single strongest determinant of survival?

Output: Age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the single strongest determinant of survival?. ### Response: Age.


Instruction: What is important to quantify as accurately as possible?

Output: thepatient’s prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to quantify as accurately as possible?. ### Response: thepatient’s prognosis.


Instruction: What are two other factors that have conflicting and less important effects on risk?

Output: ethnicity andsex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two other factors that have conflicting and less important effects on risk?. ### Response: ethnicity andsex.


Instruction: Smoking, hypertension, diabetes, diabetes mellitus, and sedentary lifestyle confer a greater risk of what?

Output: complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Smoking, hypertension, diabetes, diabetes mellitus, and sedentary lifestyle confer a greater risk of what?. ### Response: complications.


Instruction: What are the most important non-cardiac conditions to influence prognosis?

Output: Diabetes mellitus,230chronic kidney disease (CKD),231chronic pulmonarydisease, and malignancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the most important non-cardiac conditions to influence prognosis?. ### Response: Diabetes mellitus,230chronic kidney disease (CKD),231chronic pulmonarydisease, and malignancy.


Instruction: Heart failure, PAD, andcerebrovascular diseases are strong pro-gnostic risk fac-tors for mortality?

Output: Cardiovascular comorbidities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Heart failure, PAD, andcerebrovascular diseases are strong pro-gnostic risk fac-tors for mortality?. ### Response: Cardiovascular comorbidities.


Instruction: Depression repeatedlyhas been shown to be strongly and independentlyassociated with what?

Output: worse survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Depression repeatedlyhas been shown to be strongly and independentlyassociated with what?. ### Response: worse survival.


Instruction: Diabetes mellitus,230chronic kidney disease,231chronic pulmonarydisease, and malignancy are what type of medical condition?

Output: noncar-diac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diabetes mellitus,230chronic kidney disease,231chronic pulmonarydisease, and malignancy are what type of medical condition?. ### Response: noncar-diac.


Instruction: What has been shown to be strongly and independentlyassociated with worse survival?

Output: Depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to be strongly and independentlyassociated with worse survival?. ### Response: Depression.


Instruction: Poor social support, poverty,and stress are also associated with what?

Output: adverseprognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Poor social support, poverty,and stress are also associated with what?. ### Response: adverseprognosis.


Instruction: What is associated significantly withsurvival and the incidence of subsequent ACS?

Output: Patients’ symptoms, functional capacity,and quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated significantly withsurvival and the incidence of subsequent ACS?. ### Response: Patients’ symptoms, functional capacity,and quality of life.


Instruction: What was second only to age in predictingmortality in a large prospective cohort of patients in the VeteransAffairs healthcare system?

Output: physical limitations due toangina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was second only to age in predictingmortality in a large prospective cohort of patients in the VeteransAffairs healthcare system?. ### Response: physical limitations due toangina.


Instruction: What is more expensive than overlapping DOAC therapy?

Output: therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more expensive than overlapping DOAC therapy?. ### Response: therapy.


Instruction: Why may patients prefer DOAC overlap?

Output: they would avoid the inconvenience andexpense of LMWH injections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why may patients prefer DOAC overlap?. ### Response: they would avoid the inconvenience andexpense of LMWH injections.


Instruction: Careful INR monitoring during transitionsto VKA is always required, regardless of what?

Output: bridging strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Careful INR monitoring during transitionsto VKA is always required, regardless of what?. ### Response: bridging strategy.


Instruction: What is the net benefit/harm associated with using LMWH-bridgingtherapy during transitions from DOAC to VKA?

Output: 27 NOVEMBER 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the net benefit/harm associated with using LMWH-bridgingtherapy during transitions from DOAC to VKA?. ### Response: 27 NOVEMBER 2018.


Instruction: What is the name of the study that combines catheterization and Doppler echocardiographic study?

Output: Diagnostic Testing: Cardiac Catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that combines catheterization and Doppler echocardiographic study?. ### Response: Diagnostic Testing: Cardiac Catheterization.


Instruction: What is a name for the procedure that involves balloon dilata-tion of the mitral valve?

Output: Percutaneous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a name for the procedure that involves balloon dilata-tion of the mitral valve?. ### Response: Percutaneous.


Instruction: How many patients underwent percutaneous balloon mitral valvotomy?

Output: 130

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent percutaneous balloon mitral valvotomy?. ### Response: 130.


Instruction: What is an analysis of echocardiographic variables related to outcome and the mechanism of dilatation?

Output: Percutaneous balloon dilata-tion of the mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an analysis of echocardiographic variables related to outcome and the mechanism of dilatation?. ### Response: Percutaneous balloon dilata-tion of the mitral valve.


Instruction: What is a significa-tion of commissural calcification on outcome of mitral balloon valvotomy?

Output: 12. Sutaria N, Northridge DB, Shaw TR. Significance of commissural calcifica-tion on outcome of mitral balloon valvotomy. Heart. 2000;84:398–402. 13. Gajjala OR, Durgaprasad R, Velam V, et al. New integrated approach to percutaneous mitral valvuloplasty combining Wilkins score with com-missural calcium score and commissural area ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a significa-tion of commissural calcification on outcome of mitral balloon valvotomy?. ### Response: 12. Sutaria N, Northridge DB, Shaw TR. Significance of commissural calcifica-tion on outcome of mitral balloon valvotomy. Heart. 2000;84:398–402. 13. Gajjala OR, Durgaprasad R, Velam V, et al. New integrated approach to percutaneous mitral valvuloplasty combining Wilkins score with com-missural calcium score and commissural area ratio.


Instruction: Gajjala OR, Durgaprasad are what?

Output: R, Velam V

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Gajjala OR, Durgaprasad are what?. ### Response: R, Velam V.


Instruction: What is a new integrated approach to percutaneous mitral valvuloplasty combining Wilkins score with com-missural calcium score and commissural area ratio?

Output: Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new integrated approach to percutaneous mitral valvuloplasty combining Wilkins score with com-missural calcium score and commissural area ratio?. ### Response: Echocardiography.


Instruction: What is the name of the procedure that uses mitral balloon valvotomy?

Output: Circu-lation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure that uses mitral balloon valvotomy?. ### Response: Circu-lation.


Instruction: What is the effect of transmitral gradient and left atrial and ventricular compliance on mitral pressure half-time after percutaneous mitral valvotomy?

Output: Inaccuracy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of transmitral gradient and left atrial and ventricular compliance on mitral pressure half-time after percutaneous mitral valvotomy?. ### Response: Inaccuracy.


Instruction: What is a diagnostic test for mitral valve stenosis?

Output: Cardiac Catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a diagnostic test for mitral valve stenosis?. ### Response: Cardiac Catheterization.


Instruction: Horstkotte D, Niehues R, Strauer BE. Pathomorphological aspects, aetiology and natural history of acquired what?

Output: mitral valve stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Horstkotte D, Niehues R, Strauer BE. Pathomorphological aspects, aetiology and natural history of acquired what?. ### Response: mitral valve stenosis.


Instruction: What is a natural history of acquired mitral valve stenosis?

Output: Pathomorphological aspects, aeti-ology and natural history of acquired mitral valve stenosis. Eur Heart J. 1991;12(suppl B):55–60. 2. Rinkevich D, Lessick J, Mutlak D, et al. Natural history of moderate mitral valve stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a natural history of acquired mitral valve stenosis?. ### Response: Pathomorphological aspects, aeti-ology and natural history of acquired mitral valve stenosis. Eur Heart J. 1991;12(suppl B):55–60. 2. Rinkevich D, Lessick J, Mutlak D, et al. Natural history of moderate mitral valve stenosis.


Instruction: When did Eur Heart J. 1991 issue 12(suppl B):55-60?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 1991 issue 12(suppl B):55-60?. ### Response: 1991.


Instruction: What is the name of the disease that is characterized by natural history and natural history?

Output: mitral valve stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that is characterized by natural history and natural history?. ### Response: mitral valve stenosis.


Instruction: In what year did Isr Med Assoc J. publish?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Isr Med Assoc J. publish?. ### Response: 2003.


Instruction: Doppler echocardiographic assessment of long-term progression of mitral stenosis in 103 patients: valve area and right heart disease?

Output: J Am Coll Cardiol. 1996;28:472

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Doppler echocardiographic assessment of long-term progression of mitral stenosis in 103 patients: valve area and right heart disease?. ### Response: J Am Coll Cardiol. 1996;28:472.


Instruction: When did J Am Coll Cardiol. 1996;28:472–9.6.2.1.4?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 1996;28:472–9.6.2.1.4?. ### Response: 1996.


Instruction: What is the diagnostic testing for Cardiac Catheterization?

Output: Exercise Testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diagnostic testing for Cardiac Catheterization?. ### Response: Exercise Testing.


Instruction: What was measured in patients with mitral stenosis?

Output: transmitral gradient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was measured in patients with mitral stenosis?. ### Response: transmitral gradient.


Instruction: What was done in a simultaneous catheterization and Doppler echocardiographic study?

Output: Accurate measurement of the transmitral gradient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was done in a simultaneous catheterization and Doppler echocardiographic study?. ### Response: Accurate measurement of the transmitral gradient.


Instruction: When did J Am Coll Cardiol. 1994;24:152–8?

Output: 1996;28:472–9.6.2.1.4. Diagnostic Testing: Cardiac Catheterization 1. Nishimura RA, Rihal CS, Tajik AJ, et al. Accurate measurement of the transmitral gradient in patients with mitral stenosis: a simultaneous catheterization and Doppler echocardiographic study. J Am Coll Cardiol. 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 1994;24:152–8?. ### Response: 1996;28:472–9.6.2.1.4. Diagnostic Testing: Cardiac Catheterization 1. Nishimura RA, Rihal CS, Tajik AJ, et al. Accurate measurement of the transmitral gradient in patients with mitral stenosis: a simultaneous catheterization and Doppler echocardiographic study. J Am Coll Cardiol. 1994.


Instruction: What is the name of the generalized formulation of the Gorlin formula for calculating the area of the stenotic mitral valve?

Output: Gorlin WB, Gorlin R.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the generalized formulation of the Gorlin formula for calculating the area of the stenotic mitral valve?. ### Response: Gorlin WB, Gorlin R..


Instruction: What does Cheitlin MD do?

Output: Stress echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Cheitlin MD do?. ### Response: Stress echocardiography.


Instruction: What is a diagnostic test for mitral stenosis?

Output: Cardiac Catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a diagnostic test for mitral stenosis?. ### Response: Cardiac Catheterization.


Instruction: When is stress echocardiography useful?

Output: 2004;43:402–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is stress echocardiography useful?. ### Response: 2004;43:402–.


Instruction: What is the value of exercise Doppler-echocar -diography?

Output: patients with mitral stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of exercise Doppler-echocar -diography?. ### Response: patients with mitral stenosis.


Instruction: Int J Cardiol. 1994;45:219–26 what type of stenosis?

Output: mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol. 1994;45:219–26 what type of stenosis?. ### Response: mitral.


Instruction: What is the name of the disease that is associated with rheumatic mitral stenoses?

Output: right heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that is associated with rheumatic mitral stenoses?. ### Response: right heart disease.


Instruction: How is the valvular reserve capacity assessed in patients with aortic stenosis? What is a hemodynamic dilemma of combined mitral and aartic stenotic stenoids?

Output: Dynamic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the valvular reserve capacity assessed in patients with aortic stenosis? What is a hemodynamic dilemma of combined mitral and aartic stenotic stenoids?. ### Response: Dynamic.


Instruction: What is the hemodynamic dilemma of combined mitral and aortic stenosis?

Output: Addressing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the hemodynamic dilemma of combined mitral and aortic stenosis?. ### Response: Addressing.


Instruction: Catheter Cardiovasc Interv. 2008;71:944–9.

Output: mitral stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Catheter Cardiovasc Interv. 2008;71:944–9.. ### Response: mitral stenosis.


Instruction: What is the purpose of this statement?

Output: an educational tool for neurologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of this statement?. ### Response: an educational tool for neurologists.


Instruction: What are the risk factors that are unique to and more common in women?

Output: obesity/metabolic syndrome, atrial fibrillation, and migraine with aura

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risk factors that are unique to and more common in women?. ### Response: obesity/metabolic syndrome, atrial fibrillation, and migraine with aura.


Instruction: What are the risk factors for migraine with aura, obesity, metabolic syndrome, and atrial fibrillation?

Output: more common in women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risk factors for migraine with aura, obesity, metabolic syndrome, and atrial fibrillation?. ### Response: more common in women.


Instruction: What group members were nominated by the committee chair on the basis of previous work in relevant fields?

Output: Writing group members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group members were nominated by the committee chair on the basis of previous work in relevant fields?. ### Response: Writing group members.


Instruction: Who approved the committee?

Output: AHA Science Advisory and Coordinating Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who approved the committee?. ### Response: AHA Science Advisory and Coordinating Committee.


Instruction: What committee reviewed articles on adults using computerized searches of the medical literature?

Output: Scientific Statement Oversight Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What committee reviewed articles on adults using computerized searches of the medical literature?. ### Response: Scientific Statement Oversight Committee.


Instruction: How is the evidence organized?

Output: within the context of the AHA framework

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the evidence organized?. ### Response: within the context of the AHA framework.


Instruction: What is the AHA/American College of Cardiology method of classifying the level of certainty?

Output: AHA Stroke Council

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHA/American College of Cardiology method of classifying the level of certainty?. ### Response: AHA Stroke Council.


Instruction: What is the AHA's internal peer review of a document?

Output: Stroke Council Leadership review, and Scientific Statements Oversight Committee review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHA's internal peer review of a document?. ### Response: Stroke Council Leadership review, and Scientific Statements Oversight Committee review.


Instruction: What committee reviewed the document before it was approved?

Output: Scientific Statements Oversight Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What committee reviewed the document before it was approved?. ### Response: Scientific Statements Oversight Committee.


Instruction: Who approved the approval of the document by the Scientific Statements Oversight Committee?

Output: American Heart Association (AHA) Stroke Council

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who approved the approval of the document by the Scientific Statements Oversight Committee?. ### Response: American Heart Association (AHA) Stroke Council.


Instruction: What is the name of the committee that provides current evidence, research gaps, and recommendations on the risk of stroke related to preeclampsia, oral contraceptives, menopause, and hormone replacement?

Output: Scientific Statement Oversight Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that provides current evidence, research gaps, and recommendations on the risk of stroke related to preeclampsia, oral contraceptives, menopause, and hormone replacement?. ### Response: Scientific Statement Oversight Committee.


Instruction: What are some of the risk factors more common in women?

Output: obesity/metabolic syndrome, atrial fibrillation, and migraine with aura

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the risk factors more common in women?. ### Response: obesity/metabolic syndrome, atrial fibrillation, and migraine with aura.


Instruction: What is a female-specific stroke risk score warranted for?

Output: To more accurately reflect the risk of stroke in women across the lifespan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a female-specific stroke risk score warranted for?. ### Response: To more accurately reflect the risk of stroke in women across the lifespan.


Instruction: What is atrial fibrillation?

Output: hormone replacement therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atrial fibrillation?. ### Response: hormone replacement therapy.


Instruction: Atrial fibrillation  hormone replacement therapy  menopause  metabolic syndrome X  preeclampsia  sex differences  stroke Guidelines for the Prevention of Stroke in Women

Output: ibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation  hormone replacement therapy  menopause  metabolic syndrome X  preeclampsia  sex differences  stroke Guidelines for the Prevention of Stroke in Women. ### Response: ibrillation.


Instruction: Who affirms the value of this guideline as an educational tool for neurologists?

Output: The American Academy of Neurology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who affirms the value of this guideline as an educational tool for neurologists?. ### Response: The American Academy of Neurology.


Instruction: Who is the Chair of the American Association of Neurological Surgeons?

Output: Cheryl Bushnell

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of the American Association of Neurological Surgeons?. ### Response: Cheryl Bushnell.


Instruction: What is the Vice-Chair of FAHA?

Output: Louise D. McCullough

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Vice-Chair of FAHA?. ### Response: Louise D. McCullough.


Instruction: Who is Vice-Chair?

Output: Louise D. McCullough

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Vice-Chair?. ### Response: Louise D. McCullough.


Instruction: What is Monique V. Chireau's profession?

Output: MD, MPH, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Monique V. Chireau's profession?. ### Response: MD, MPH, FAHA.


Instruction: Who is Ileana L. Pia?

Output: MD, MPH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Ileana L. Pia?. ### Response: MD, MPH.


Instruction: Who is Lisabeth?

Output: Lynda D. Lisabeth, PhD, MPH, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Lisabeth?. ### Response: Lynda D. Lisabeth, PhD, MPH, FAHA.


Instruction: What is Mathew J. Reeves' specialty?

Output: DVM, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Mathew J. Reeves' specialty?. ### Response: DVM, FAHA.


Instruction: What is t he rationale and impact section on?

Output: pr eventing recurr ence aft er ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he rationale and impact section on?. ### Response: pr eventing recurr ence aft er ablation.


Instruction: What are the details of the evidence and committee?

Output: Full details of t he evidence and t he committ ee's discussion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the details of the evidence and committee?. ### Response: Full details of t he evidence and t he committ ee's discussion.


Instruction: What are antiarrh ythmic drugs aft er ablation?

Output: pacing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are antiarrh ythmic drugs aft er ablation?. ### Response: pacing.


Instruction: What do people with permanent atrial fibrillation wit h pacing and atrioventricular node ablation consider?

Output: sympt oms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do people with permanent atrial fibrillation wit h pacing and atrioventricular node ablation consider?. ### Response: sympt oms.


Instruction: What is thought to be caused by high v entricular rat es?

Output: left v entricular dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is thought to be caused by high v entricular rat es?. ### Response: left v entricular dysfunction.


Instruction: When considering pacing and atrio ventricular node ablation, r eassess sympt oms and the consequent need f?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When considering pacing and atrio ventricular node ablation, r eassess sympt oms and the consequent need f?. ### Response: 25.


Instruction: What has been carried out and t he consequent need f or ablation aft er pacing was carried out?

Output: drug tr eatment fur ther optimised

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been carried out and t he consequent need f or ablation aft er pacing was carried out?. ### Response: drug tr eatment fur ther optimised.


Instruction: What was done and drug tr eatment fur ther optimised?

Output: pacing and atrio ventricular node ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was done and drug tr eatment fur ther optimised?. ### Response: pacing and atrio ventricular node ablation.


Instruction: Consider left atrial cat heter ablation bef ore what?

Output: pacing and atrio ventricular node ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Consider left atrial cat heter ablation bef ore what?. ### Response: pacing and atrio ventricular node ablation.


Instruction: What type of atrial fibrillation can be caused by node ablation?

Output: permanent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of atrial fibrillation can be caused by node ablation?. ### Response: permanent.


Instruction: What is the term for non-permanent (par oxysmal or persist ent) atrial fibrosis?

Output: permanent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for non-permanent (par oxysmal or persist ent) atrial fibrosis?. ### Response: permanent.


Instruction: How many manag emen t for people pr esen ting acu tely with atrial fi brillation Rate and r hythm c ontrol?

Output: 1.8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many manag emen t for people pr esen ting acu tely with atrial fi brillation Rate and r hythm c ontrol?. ### Response: 1.8.


Instruction: Atrial fibrillation Rate and r hythm c ontrol for pe ople pr esen ting acu tely 1.8.1 Carry out emer gency electrical car dioversion, without dela ying t o achie ve anticoagulation?

Output: atrial fibrillation pr esenting acut ely without lif e-threatening haemodynamic instability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation Rate and r hythm c ontrol for pe ople pr esen ting acu tely 1.8.1 Carry out emer gency electrical car dioversion, without dela ying t o achie ve anticoagulation?. ### Response: atrial fibrillation pr esenting acut ely without lif e-threatening haemodynamic instability.


Instruction: Atrial fibrillation: diagnosis and management (NG196) NICE 2022. What is caused by haemodynamic instability?

Output: life-threatening haemodynamic instability caused b y new-onset atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation: diagnosis and management (NG196) NICE 2022. What is caused by haemodynamic instability?. ### Response: life-threatening haemodynamic instability caused b y new-onset atrial fibrillation.


Instruction: What is the last updat ed 30 June 2021?

Output: Page 20of 47

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 30 June 2021?. ### Response: Page 20of 47.


Instruction: What is the 2019 AHA/ASA Guideline on the Primary Prevention of Cardiovascular Disease19ACC/AHA 2019 Focused Update of what guideline for the management of patients with Atrial Fibrillation?

Output: 2014 AHA/ACC/HRS Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2019 AHA/ASA Guideline on the Primary Prevention of Cardiovascular Disease19ACC/AHA 2019 Focused Update of what guideline for the management of patients with Atrial Fibrillation?. ### Response: 2014 AHA/ACC/HRS Guideline.


Instruction: What are the 2019 Guidelines for the Management of Patients With Valvular Heart Disease?

Output: 33ACC/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2019 Guidelines for the Management of Patients With Valvular Heart Disease?. ### Response: 33ACC/AHA.


Instruction: What is the Management of Patients With Valvular Heart Disease33ACC/AHA 2020AHA/ASA statements Diagnosis and Management of Cerebral Venous Thrombosis22AHA-ASA 2011 Cervical Arterial Dissections and Association With What?

Output: Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Management of Patients With Valvular Heart Disease33ACC/AHA 2020AHA/ASA statements Diagnosis and Management of Cerebral Venous Thrombosis22AHA-ASA 2011 Cervical Arterial Dissections and Association With What?. ### Response: Guideline.


Instruction: What are the Physical Activity and Exercise Recommendations for Stroke Survivors34AHA /ASA 2014 Spontaneous Coronary Artery Dissection?

Output: Current State of the Science

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Physical Activity and Exercise Recommendations for Stroke Survivors34AHA /ASA 2014 Spontaneous Coronary Artery Dissection?. ### Response: Current State of the Science.


Instruction: What is the current state of the science regarding Spontaneous Coronary Artery Dissection?

Output: Current State of the Science34aAHA/ASA 2018AHA/ASA presidential advisory     Defining Optimal Brain Health in Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current state of the science regarding Spontaneous Coronary Artery Dissection?. ### Response: Current State of the Science34aAHA/ASA 2018AHA/ASA presidential advisory     Defining Optimal Brain Health in Adults.


Instruction: What year was the Presidential advisory Defining Optimal Brain Health in Adults issued?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the Presidential advisory Defining Optimal Brain Health in Adults issued?. ### Response: 2018.


Instruction: AANS is the acronym for what?

Output: American

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AANS is the acronym for what?. ### Response: American.


Instruction: What is the acronym for American Academy of Physician Assistants?

Output: AAPA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American Academy of Physician Assistants?. ### Response: AAPA.


Instruction: What does ABC stand for?

Output: Association of Black Cardiologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ABC stand for?. ### Response: Association of Black Cardiologists.


Instruction: ACR stands for American College of Radiology.

Output: ACPM, American College of Preventive Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ACR stands for American College of Radiology.. ### Response: ACPM, American College of Preventive Medicine.


Instruction: AGS stands for what?

Output: American Geriatrics Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AGS stands for what?. ### Response: American Geriatrics Society.


Instruction: What is the acronym for American Geriatrics Society?

Output: AGS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American Geriatrics Society?. ### Response: AGS.


Instruction: What does AHA stand for?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AHA stand for?. ### Response: American Heart Association.


Instruction: AHA stands for American Heart Association; ASA stands for what?

Output: American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AHA stands for American Heart Association; ASA stands for what?. ### Response: American Stroke Association.


Instruction: ASH stands for What?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ASH stands for What?. ### Response: American Heart Association.


Instruction: CNS stands for Congress of Neurological Surgeons.

Output: CNS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CNS stands for Congress of Neurological Surgeons.. ### Response: CNS.


Instruction: What does NLA stand for?

Output: National Lipid Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NLA stand for?. ### Response: National Lipid Association.


Instruction: What is the acronym for National Lipid Association?

Output: NLA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for National Lipid Association?. ### Response: NLA.


Instruction: Which acronym stands for Preventive Cardiovascular Nurses association?

Output: PCNA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which acronym stands for Preventive Cardiovascular Nurses association?. ### Response: PCNA.


Instruction: SAIP stands for what?

Output: Society of Atherosclerosis Imaging and Prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: SAIP stands for what?. ### Response: Society of Atherosclerosis Imaging and Prevention.


Instruction: SCAI stands for What?

Output: Society for Cardiovascular Angiography and Interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: SCAI stands for What?. ### Response: Society for Cardiovascular Angiography and Interventions.


Instruction: What is SVS?

Output: Society for Vascular Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SVS?. ### Response: Society for Vascular Surgery.


Instruction: What is TOS?

Output: The Obesity Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TOS?. ### Response: The Obesity Society.


Instruction: When was this publication released?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication released?. ### Response: April 28, 2023.


Instruction: What drug induced myocardial infarc-tion with elevated troponin I?

Output: Methamphetamine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug induced myocardial infarc-tion with elevated troponin I?. ### Response: Methamphetamine.


Instruction: What year did Am J Emerg Med issue 24:132–4?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Am J Emerg Med issue 24:132–4?. ### Response: 2006.


Instruction: How did Chen JP describe methamphetamine-associated acute myocardial infarction with normal coronary arteries?

Output: refractory global coro-nary microvascular spasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Chen JP describe methamphetamine-associated acute myocardial infarction with normal coronary arteries?. ### Response: refractory global coro-nary microvascular spasm.


Instruction: What is the name of the study in which verapamil was used to manage unstable angina at rest?

Output: double-blind cross-over study in coronary care unit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study in which verapamil was used to manage unstable angina at rest?. ### Response: double-blind cross-over study in coronary care unit.


Instruction: What drug was used in a double-blind cross-over study in coronary care unit?

Output: verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was used in a double-blind cross-over study in coronary care unit?. ### Response: verapamil.


Instruction: What is the name of the study that investigated the use of amlodipine in vasospastic angina?

Output: Amlodipine Study 160 Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the use of amlodipine in vasospastic angina?. ### Response: Amlodipine Study 160 Group.


Instruction: What isosorbide-5-mononitrate versus nifedipine effective in preventing?

Output: spontaneous and ergonovine-induced myocardial ischaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isosorbide-5-mononitrate versus nifedipine effective in preventing?. ### Response: spontaneous and ergonovine-induced myocardial ischaemia.


Instruction: What is the effect of benidipine in patients with vasospastic angina?

Output: Prognostic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of benidipine in patients with vasospastic angina?. ### Response: Prognostic.


Instruction: What does benidipine have in comparison with diltiazem and amlo-dipine?

Output: Prognostic effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does benidipine have in comparison with diltiazem and amlo-dipine?. ### Response: Prognostic effects.


Instruction: How many cardiology institutes did Kimura E, Kishida H visit in Japan?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cardiology institutes did Kimura E, Kishida H visit in Japan?. ### Response: 11.


Instruction: What is the name of the drug that is used to treat variant angina?

Output: isosorbide-5-mononitrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat variant angina?. ### Response: isosorbide-5-mononitrate.


Instruction: What is a supersensitive dilator response to nitroglycerin but not to atrial natriuretic peptide in spastic cor -onary arteries?

Output: coronary spastic angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a supersensitive dilator response to nitroglycerin but not to atrial natriuretic peptide in spastic cor -onary arteries?. ### Response: coronary spastic angina.


Instruction: What was the Am J Cardiol. 1997;79:606–10. 759. Tani S, Nagao K, Anazawa T, et al. Treatment of coronary spastic angina with a statin in rats?

Output: pilot study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Am J Cardiol. 1997;79:606–10. 759. Tani S, Nagao K, Anazawa T, et al. Treatment of coronary spastic angina with a statin in rats?. ### Response: pilot study.


Instruction: What is the effect of fluvastatin on coronary spasm after withdrawal of calcium-channel blocker?

Output: preventing spontaneous and ergonovine-induced myocardial ischaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of fluvastatin on coronary spasm after withdrawal of calcium-channel blocker?. ### Response: preventing spontaneous and ergonovine-induced myocardial ischaemia.


Instruction: What is a 3-hydroxy-3-meth-ylglutaryl coenzyme A reductase inhibitor?

Output: fluvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 3-hydroxy-3-meth-ylglutaryl coenzyme A reductase inhibitor?. ### Response: fluvastatin.


Instruction: What is fluvastatin?

Output: 3-hydroxy-3-meth-ylglutaryl coenzyme A reductase inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is fluvastatin?. ### Response: 3-hydroxy-3-meth-ylglutaryl coenzyme A reductase inhibitor.


Instruction: What is a major risk factor for coro-nary spasm?

Output: Cigarette smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major risk factor for coro-nary spasm?. ### Response: Cigarette smoking.


Instruction: What determines long-term prognosis of vasospastic angina treated with calcium channel antagonists?

Output: Lesion severity and hypercholester -olemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What determines long-term prognosis of vasospastic angina treated with calcium channel antagonists?. ### Response: Lesion severity and hypercholester -olemia.


Instruction: What is the most important determinant of coronary artery spasm?

Output: clinical risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most important determinant of coronary artery spasm?. ### Response: clinical risk factors.


Instruction: What is the name of the drug used to treat vasospastic angina?

Output: calcium channel antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat vasospastic angina?. ### Response: calcium channel antagonists.


Instruction: What is ergonovine maleate associated with?

Output: focal vasospasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ergonovine maleate associated with?. ### Response: focal vasospasm.


Instruction: What is a common cause of coronary artery spasm?

Output: Methamphetamine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of coronary artery spasm?. ### Response: Methamphetamine.


Instruction: What is an important requirement if drug-eluting stents are to be used?

Output: dual-antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important requirement if drug-eluting stents are to be used?. ### Response: dual-antiplatelet therapy.


Instruction: What did the writing committee list important tasks to bedone by the care team?

Output: before the procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing committee list important tasks to bedone by the care team?. ### Response: before the procedure.


Instruction: What can be used to document the patient's renal function?

Output: procedural strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to document the patient's renal function?. ### Response: procedural strategies.


Instruction: What can in fluency both the patient’s candidacy for the procedure and procedural strategies de.g., amount of iodinatedcontrast?

Output: renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can in fluency both the patient’s candidacy for the procedure and procedural strategies de.g., amount of iodinatedcontrast?. ### Response: renal function.


Instruction: What did the writing committee put the procedure in the context of?

Output: patients ’longitudinal disease process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing committee put the procedure in the context of?. ### Response: patients ’longitudinal disease process.


Instruction: What did they consider that procedural quality must extend beyond?

Output: the laboratory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did they consider that procedural quality must extend beyond?. ### Response: the laboratory.


Instruction: What should the laboratory involve implementationof?

Output: appropriate secondary prevention cardiac rehabilitationand medications to modify long-term risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the laboratory involve implementationof?. ### Response: appropriate secondary prevention cardiac rehabilitationand medications to modify long-term risk.


Instruction: What should medications modify long-term risk?

Output: secondary prevention cardiac rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should medications modify long-term risk?. ### Response: secondary prevention cardiac rehabilitation.


Instruction: Thewriting committee considered other indicators of what?

Output: quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Thewriting committee considered other indicators of what?. ### Response: quality.


Instruction: What does the metric set provide a solid foundation for?

Output: quality improvement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the metric set provide a solid foundation for?. ### Response: quality improvement.


Instruction: What is the field of qualityassessment and performance measurement in PCI?

Output: Interventions Performance Measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the field of qualityassessment and performance measurement in PCI?. ### Response: Interventions Performance Measures.


Instruction: Who is the Chair of the ACC/AHA Task Force on Performance Measures?

Output: Eric D. Peterson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of the ACC/AHA Task Force on Performance Measures?. ### Response: Eric D. Peterson.


Instruction: Who created the first performance measure set?

Output: Writing Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who created the first performance measure set?. ### Response: Writing Committee.


Instruction: Who created the first performance measure set in this area?

Output: Writing Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who created the first performance measure set in this area?. ### Response: Writing Committee.


Instruction: How many measures does the writing committee present in the measure set?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many measures does the writing committee present in the measure set?. ### Response: 11.


Instruction: What are the 11 measures intended for?

Output: ambulatory and hospital(inpatient) settings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 11 measures intended for?. ### Response: ambulatory and hospital(inpatient) settings.


Instruction: What is the 2013 PCIperformance measurement set available on the PCPI Web site at http://www.ama-assn.org/apps/listserv/x-check/qmeasure.cgi?

Output: Scope of the Problem

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 PCIperformance measurement set available on the PCPI Web site at http://www.ama-assn.org/apps/listserv/x-check/qmeasure.cgi?. ### Response: Scope of the Problem.


Instruction: What type of cardiology did the writing committee specialize in?

Output: interventional

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of cardiology did the writing committee specialize in?. ### Response: interventional.


Instruction: What kind of cardiolgy did the committee include?

Output: general

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What kind of cardiolgy did the committee include?. ### Response: general.


Instruction: What do studies use to evaluate sodium intake?

Output: pot urine sodium measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do studies use to evaluate sodium intake?. ### Response: pot urine sodium measurements.


Instruction: What is the current controversy about assessing sodium intake using random “spot”urine samples?

Output: the accuracy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current controversy about assessing sodium intake using random “spot”urine samples?. ### Response: the accuracy.


Instruction: What is required to evaluate the health impacts of very low-sodium intakes in CKDpopulations?

Output: Future studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required to evaluate the health impacts of very low-sodium intakes in CKDpopulations?. ### Response: Future studies.


Instruction: Recent small, single-center clinical trials evaluating chronicoral sodium bicarbonate supplementationversus placebo have not found changes in what?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent small, single-center clinical trials evaluating chronicoral sodium bicarbonate supplementationversus placebo have not found changes in what?. ### Response: BP.


Instruction: What may be associated with sodium intake?

Output: anion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with sodium intake?. ### Response: anion.


Instruction: What is required to determine if relationships of sodium intake with BP are influenced by the accompanying anion?

Output: Future research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required to determine if relationships of sodium intake with BP are influenced by the accompanying anion?. ### Response: Future research.


Instruction: In the general population, what has been demonstrated to lower BP?

Output: potassium-containing salt sub-stitutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the general population, what has been demonstrated to lower BP?. ### Response: potassium-containing salt sub-stitutes.


Instruction: Why have people with CKD been excluded from clinical trialsevaluating potassium-based salt substitutes?

Output: lower BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why have people with CKD been excluded from clinical trialsevaluating potassium-based salt substitutes?. ### Response: lower BP.


Instruction: What is associated with higher potassium intake?

Output: higher risk of CKD progression and CV disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with higher potassium intake?. ### Response: higher risk of CKD progression and CV disease.


Instruction: What may have healthbenefits or unique risks when applied to CKD populations?

Output: potassium-containing salt substitutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have healthbenefits or unique risks when applied to CKD populations?. ### Response: potassium-containing salt substitutes.


Instruction: People of what ancestry are disproportionately repre-sented inCKD?

Output: African

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People of what ancestry are disproportionately repre-sented inCKD?. ### Response: African.


Instruction: Prior systematic reviews sug-gest that reductions in sodium intake may result in larger reduction in what?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prior systematic reviews sug-gest that reductions in sodium intake may result in larger reduction in what?. ### Response: BP.


Instruction: What are CKD patients of African and Asian ancestry compared to?

Output: Caucasians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are CKD patients of African and Asian ancestry compared to?. ### Response: Caucasians.


Instruction: What is uncertain andshould be evaluated in future studies?

Output: Whether such racial differencescan also be found in CKD populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uncertain andshould be evaluated in future studies?. ### Response: Whether such racial differencescan also be found in CKD populations.


Instruction: What is needed to tailor physical activity intensity and supervision to individual CKD patients?

Output: Identi ﬁcation of thesefactors and algorithms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to tailor physical activity intensity and supervision to individual CKD patients?. ### Response: Identi ﬁcation of thesefactors and algorithms.


Instruction: What is added to salt in some countries?

Output: Iodine supplements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is added to salt in some countries?. ### Response: Iodine supplements.


Instruction: What is needed to determine if restrictingsodium intake in CKD populations may contribute to toiodine deficiency?

Output: Future studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to determine if restrictingsodium intake in CKD populations may contribute to toiodine deficiency?. ### Response: Future studies.


Instruction: What is the name of the guideline for chronic heart failure?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for chronic heart failure?. ### Response: NICE 2018.


Instruction: What is NICE 2018 subject to?

Output: Notice of rights

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018 subject to?. ### Response: Notice of rights.


Instruction: How do you ensure effective communication between care settings and clinical services?

Output: lead a full review of the person’s heart failure care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do you ensure effective communication between care settings and clinical services?. ### Response: lead a full review of the person’s heart failure care.


Instruction: How often should a heart failure patient be recalled?

Output: at least every 6  months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often should a heart failure patient be recalled?. ### Response: at least every 6  months.


Instruction: How often is a full review of a person’s heart failure care conducted?

Output: at least every 6  months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often is a full review of a person’s heart failure care conducted?. ### Response: at least every 6  months.


Instruction: What is the term for a long-term c onditions review?

Output: recall the person at least every 6  months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for a long-term c onditions review?. ### Response: recall the person at least every 6  months.


Instruction: What should a person with heart failure do to ensure that changes to their clinical record are understood and agreed by them?

Output: update the summary and clinical record

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a person with heart failure do to ensure that changes to their clinical record are understood and agreed by them?. ### Response: update the summary and clinical record.


Instruction: What should be shared with the specialist heart failure MDT if needed?

Output: arrange access to specialist heart failure services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be shared with the specialist heart failure MDT if needed?. ### Response: arrange access to specialist heart failure services.


Instruction: What is NICE's guideline on acute heart failure?

Output: 76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE's guideline on acute heart failure?. ### Response: 76.


Instruction: What should people with heart failure be discharged from hospital only when their clinical condition is stable and the management plan is optimised?

Output: 76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should people with heart failure be discharged from hospital only when their clinical condition is stable and the management plan is optimised?. ### Response: 76.


Instruction: What should the timing of discharge take into account?

Output: the wishes of the person and their family or carer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the timing of discharge take into account?. ### Response: the wishes of the person and their family or carer.


Instruction: What is the primary care team workingin g within?

Output: specialist heart failure MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary care team workingin g within?. ### Response: specialist heart failure MDT.


Instruction: Who should take over routine management of heart failure as soon as it has been stabilised and its management optimised?

Output: team workin g within the specialist heart failure MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should take over routine management of heart failure as soon as it has been stabilised and its management optimised?. ### Response: team workin g within the specialist heart failure MDT.


Instruction: What should the specialist heart failure MDT write a summ ary for each person with heart failure?

Output: diagnosis and aetiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the specialist heart failure MDT write a summ ary for each person with heart failure?. ### Response: diagnosis and aetiology.


Instruction: What should be written for each person with heart failure?

Output: a summ ary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be written for each person with heart failure?. ### Response: a summ ary.


Instruction: What should include:  diagnosis and aetiology  medicines prescribed, monitoring of medicines, when medicines should be reviewed and any support the person needs to take them?

Output: a summ ary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should include:  diagnosis and aetiology  medicines prescribed, monitoring of medicines, when medicines should be reviewed and any support the person needs to take them?. ### Response: a summ ary.


Instruction: What should be the basis of a care plan for each person?

Output: The summary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the basis of a care plan for each person?. ### Response: The summary.


Instruction: What should include plans for managing the person's heart failure?

Output: follow -up care, rehabilitation and access to social care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should include plans for managing the person's heart failure?. ### Response: follow -up care, rehabilitation and access to social care.


Instruction: What is a process for any subsequent access to the specialist heart failure MDT if needed?

Output: a care plan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a process for any subsequent access to the specialist heart failure MDT if needed?. ### Response: a care plan.


Instruction: What is the name of the person with heart failure?

Output: 78

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person with heart failure?. ### Response: 78.


Instruction: What is the name of a healthcare coordinator?

Output: specialist heart failure nurse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a healthcare coordinator?. ### Response: specialist heart failure nurse.


Instruction: What is another name for a specialist heart failure nurse?

Output: healthcare coordinator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for a specialist heart failure nurse?. ### Response: healthcare coordinator.


Instruction: Where can you find additional sources of information?

Output: local heart failure specialist care providers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find additional sources of information?. ### Response: local heart failure specialist care providers.


Instruction: What should you do when giving information to people with heart failure?

Output: follow the recommendations in the NICE guideline on patient experience in adult NHS services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should you do when giving information to people with heart failure?. ### Response: follow the recommendations in the NICE guideline on patient experience in adult NHS services.


Instruction: What should the family or carer of a heart failure patient receive if appropriate?

Output: Give a copy of the care plan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the family or carer of a heart failure patient receive if appropriate?. ### Response: Give a copy of the care plan.


Instruction: What is the NICE guideline on patient experience in adult NHS services?

Output: follow the recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NICE guideline on patient experience in adult NHS services?. ### Response: follow the recommendations.


Instruction: What are saccharide and tetrasaccharide fragments?

Output: Semin Thromb Hemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are saccharide and tetrasaccharide fragments?. ### Response: Semin Thromb Hemost.


Instruction: When was Semin Thromb Hemost published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Semin Thromb Hemost published?. ### Response: 2008.


Instruction: What residues contribute to the heparin-induced conformational change in antithrombin III?

Output: 3-O- and 6-O-sulfated glucosamine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What residues contribute to the heparin-induced conformational change in antithrombin III?. ### Response: 3-O- and 6-O-sulfated glucosamine.


Instruction: How many ( 20): 6454?

Output: 26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 20): 6454?. ### Response: 26.


Instruction: How many days were there in 1987?

Output: 6454 - 6461

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days were there in 1987?. ### Response: 6454 - 6461.


Instruction: What was the total number of days in 1987 in total?

Output: 6454 - 6461

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the total number of days in 1987 in total?. ### Response: 6454 - 6461.


Instruction: Anti-Xa monitoring: inter-assay variability?

Output: Thromb Haemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anti-Xa monitoring: inter-assay variability?. ### Response: Thromb Haemost.


Instruction: Thromb Haemost. 2000 ; 84 ( 6 ): 1122 - 1123.

Output: Anti-Xa monitoring: inter-assay variability .   Thromb Haemost  .   2000 ; 84 ( 6 ): 1122 - 1123 .      197

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Thromb Haemost. 2000 ; 84 ( 6 ): 1122 - 1123.. ### Response: Anti-Xa monitoring: inter-assay variability .   Thromb Haemost  .   2000 ; 84 ( 6 ): 1122 - 1123 .      197.


Instruction: Kitchen S, Iampietro

Output: Kitchen   S ,  Iampietro   R

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kitchen S, Iampietro. ### Response: Kitchen   S ,  Iampietro   R.


Instruction: What drug is used to monitor anti Xa during treatment with low molecular weight heparin or danaparoid?

Output: fonda-parinux

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used to monitor anti Xa during treatment with low molecular weight heparin or danaparoid?. ### Response: fonda-parinux.


Instruction: When was Thromb Haemost tested?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Thromb Haemost tested?. ### Response: 2008.


Instruction: What is the name of the Thromb Haemost?

Output: Thromb Haemost  .  2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Thromb Haemost?. ### Response: Thromb Haemost  .  2008.


Instruction: How many ( 4 ): 1289 - 1293?

Output: 82

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 4 ): 1289 - 1293?. ### Response: 82.


Instruction: What are the names of the authors?

Output: Rota   E ,  Bazzan   M ,  Fantino   G .  Fondaparinux-related throm-bocytopenia in a previous low-molecular-weight heparin (LMWH)-induced heparin-induced thrombocytopenia (HIT) .   Thromb Haemost  .  2008 ; 99 ( 4 ): 779 - 781 .   © 2012 American College of Chest Physicians by Kimberly Henricks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors?. ### Response: Rota   E ,  Bazzan   M ,  Fantino   G .  Fondaparinux-related throm-bocytopenia in a previous low-molecular-weight heparin (LMWH)-induced heparin-induced thrombocytopenia (HIT) .   Thromb Haemost  .  2008 ; 99 ( 4 ): 779 - 781 .   © 2012 American College of Chest Physicians by Kimberly Henricks.


Instruction: What is the name of the natural pentasaccharide?

Output: SR90107/Org31540

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the natural pentasaccharide?. ### Response: SR90107/Org31540.


Instruction: In what year did Thromb Haemost occur?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Thromb Haemost occur?. ### Response: 2008.


Instruction: How many ( 6 ): 1468 - 1473?

Output: 74

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 6 ): 1468 - 1473?. ### Response: 74.


Instruction: When did Donat F, Duret JP, Santoni A, et al. study fondaparinux sodium in healthy volunteers?

Output: 1468 - 1473

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Donat F, Duret JP, Santoni A, et al. study fondaparinux sodium in healthy volunteers?. ### Response: 1468 - 1473.


Instruction: How many healthy volunteers did Clin Pharmacokinet have in 2002?

Output: 200

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many healthy volunteers did Clin Pharmacokinet have in 2002?. ### Response: 200.


Instruction: How many (suppl 2 ): 1-9. 200?

Output: 41

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many (suppl 2 ): 1-9. 200?. ### Response: 41.


Instruction: Donat F, et al. Fondaparinux sodium is not metabolised in what?

Output: mammalian liver fractions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Donat F, et al. Fondaparinux sodium is not metabolised in what?. ### Response: mammalian liver fractions.


Instruction: What does not inhibit cytochrome P450-mediated metabolism of con-comitant drugs?

Output: Fondaparinux sodium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not inhibit cytochrome P450-mediated metabolism of con-comitant drugs?. ### Response: Fondaparinux sodium.


Instruction: 41 ( suppl 2 ): 19 - what?

Output: 26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 41 ( suppl 2 ): 19 - what?. ### Response: 26.


Instruction: What is Fondaparinux sodium mechanism of action?

Output: identiﬁ  cation of speciﬁ  c binding to puriﬁ  ed and human plasma-derived proteins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Fondaparinux sodium mechanism of action?. ### Response: identiﬁ  cation of speciﬁ  c binding to puriﬁ  ed and human plasma-derived proteins.


Instruction: Fondaparinux sodium mechanism of action: identifi cation of what type of binding to human plasma-derived proteins?

Output: speci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fondaparinux sodium mechanism of action: identifi cation of what type of binding to human plasma-derived proteins?. ### Response: speci.


Instruction: Clin Pharmacokinet. 2002 ; 41 (suppl 2 ): 11 - 18.

Output: Clin Pharmacokinet  .  2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Clin Pharmacokinet. 2002 ; 41 (suppl 2 ): 11 - 18.. ### Response: Clin Pharmacokinet  .  2002.


Instruction: How does recombinant factor VIIa reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers?

Output: Ability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does recombinant factor VIIa reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers?. ### Response: Ability.


Instruction: What is the effect of fondaparinux in healthy volunteers?

Output: pharmacoki-netics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of fondaparinux in healthy volunteers?. ### Response: pharmacoki-netics.


Instruction: How many ( 20): 2550 - 2554?

Output: 106

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 20): 2550 - 2554?. ### Response: 106.


Instruction: What is the effect of fonda-parinux on platelet activation in the presence of heparin-dependent antibodies?

Output: a blinded comparative multicenter study with unfractionated heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of fonda-parinux on platelet activation in the presence of heparin-dependent antibodies?. ### Response: a blinded comparative multicenter study with unfractionated heparin.


Instruction: Blood. 2005 ; 105 ( 1 ): 139 - what?

Output: 144

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood. 2005 ; 105 ( 1 ): 139 - what?. ### Response: 144.


Instruction: What is LMWH?

Output: low-molecular-weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LMWH?. ### Response: low-molecular-weight heparin.


Instruction: What is HIT?

Output: heparin-induced thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HIT?. ### Response: heparin-induced thrombocytopenia.


Instruction: When was the American College of Chest Physicians founded?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the American College of Chest Physicians founded?. ### Response: 2012.


Instruction: What should be used in absence of e vidence?

Output: targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used in absence of e vidence?. ### Response: targets.


Instruction: What should the focus be on in t he absence of blood pr essur e?

Output: adv erse e vents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the focus be on in t he absence of blood pr essur e?. ### Response: adv erse e vents.


Instruction: What type of blood pr essur e tar gets sho wed that t here were bot h benefit s and harms associat ed wit h a lo wer clinic syst olic blood pra sur e get of 120 mmHg?

Output: lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of blood pr essur e tar gets sho wed that t here were bot h benefit s and harms associat ed wit h a lo wer clinic syst olic blood pra sur e get of 120 mmHg?. ### Response: lower.


Instruction: What is the difference in blood pressure between type 2 diabetes and 120 mmHg?

Output: 140

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference in blood pressure between type 2 diabetes and 120 mmHg?. ### Response: 140.


Instruction: What is a benefit of the lower blood pressure?

Output: risk of harms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a benefit of the lower blood pressure?. ### Response: risk of harms.


Instruction: What is the risk of harms associated with lower blood pressure?

Output: gr eater

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of harms associated with lower blood pressure?. ### Response: gr eater.


Instruction: What is a risk from falls?

Output: injur y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk from falls?. ### Response: injur y.


Instruction: What was unclear about the implications of the SPRINT trial?

Output: adv erse e vents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was unclear about the implications of the SPRINT trial?. ### Response: adv erse e vents.


Instruction: What was a lar ge study under taken in t he sPRINT study?

Output: SPRINT trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a lar ge study under taken in t he sPRINT study?. ### Response: SPRINT trial.


Instruction: Where was a lar ge study under taken in the US?

Output: SPRINT trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was a lar ge study under taken in the US?. ### Response: SPRINT trial.


Instruction: What concerns did the committee discuss?

Output: applicability of t he population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What concerns did the committee discuss?. ### Response: applicability of t he population.


Instruction: What are aut omat ed blood pressur e devices wit h a time dela y and an isola ted rest period?

Output: The study used aut omat ed blood pressur e devices wit h a time dela y and an isolat ed rest period, which is not common practice in t he UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are aut omat ed blood pressur e devices wit h a time dela y and an isola ted rest period?. ### Response: The study used aut omat ed blood pressur e devices wit h a time dela y and an isolat ed rest period, which is not common practice in t he UK.


Instruction: What is not common practice in the UK?

Output: aut omat ed blood pressur e devices wit h a time dela y and an isolat ed rest period

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not common practice in the UK?. ### Response: aut omat ed blood pressur e devices wit h a time dela y and an isolat ed rest period.


Instruction: What could lead to lower blood pr essur e readings in UK clinical practice?

Output: t hese de vices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could lead to lower blood pr essur e readings in UK clinical practice?. ### Response: t hese de vices.


Instruction: What may have had an impact on some medicines?

Output: blood pr essur e tar gets were achie ved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have had an impact on some medicines?. ### Response: blood pr essur e tar gets were achie ved.


Instruction: What may have had an impact on t he result s?

Output: some medicines w ere stopped when blood pr essur e tar gets were achie ved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have had an impact on t he result s?. ### Response: some medicines w ere stopped when blood pr essur e tar gets were achie ved.


Instruction: What concerns did the committee discuss about applicability of?

Output: t he population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What concerns did the committee discuss about applicability of?. ### Response: t he population.


Instruction: What concerns made the evidence difficult to interpret and use to inform t he recommendations?

Output: Evidence f or lower tar gets in people with type  2 diabet es was also limit ed, wit h some e vidence t o suggest t hat lo wer blood pressur e tar gets did not r educe t he rat e of car diovascular e vents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What concerns made the evidence difficult to interpret and use to inform t he recommendations?. ### Response: Evidence f or lower tar gets in people with type  2 diabet es was also limit ed, wit h some e vidence t o suggest t hat lo wer blood pressur e tar gets did not r educe t he rat e of car diovascular e vents.


Instruction: What is included in evidence r eview D: tar gets?

Output: urther details of the committ ee's discussion of t his study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in evidence r eview D: tar gets?. ### Response: urther details of the committ ee's discussion of t his study.


Instruction: Evidence fr om a smaller study also sho wed some benefit of lo wering clinic syst olic blood pressur e tar get to what?

Output: 130  mmHg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence fr om a smaller study also sho wed some benefit of lo wering clinic syst olic blood pressur e tar get to what?. ### Response: 130  mmHg.


Instruction: What does clinic syst olic blood pressur e tar get to?

Output: 130  mmHg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does clinic syst olic blood pressur e tar get to?. ### Response: 130  mmHg.


Instruction: What did the committ ee not ed that t he study was based on?

Output: people alr eady r eceiving tr eatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committ ee not ed that t he study was based on?. ### Response: people alr eady r eceiving tr eatment.


Instruction: What did the adv erse e vents not suggest?

Output: inf ormation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the adv erse e vents not suggest?. ### Response: inf ormation.


Instruction: What type of diabetics should have evidence of lower tar?

Output: type  2 diabet es

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetics should have evidence of lower tar?. ### Response: type  2 diabet es.


Instruction: What did people with type 2 diabet es have that was also limit ed?

Output: Evidence f or lower tar gets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did people with type 2 diabet es have that was also limit ed?. ### Response: Evidence f or lower tar gets.


Instruction: What did not r educe t he rat e of car diovascular e?

Output: blood pressur e tar gets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not r educe t he rat e of car diovascular e?. ### Response: blood pressur e tar gets.


Instruction: What is NICE's guideline on type 2 diabet es in adult s?

Output: type  2 diabet es

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE's guideline on type 2 diabet es in adult s?. ### Response: type  2 diabet es.


Instruction: What does NICE recommend people with type 2 diabetes do?

Output: guideline on type  2 diabet es in adult s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NICE recommend people with type 2 diabetes do?. ### Response: guideline on type  2 diabet es in adult s.


Instruction: What is the pr esence of target or gan damage?

Output: harms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pr esence of target or gan damage?. ### Response: harms.


Instruction: What is a kidne y, cerebrovascular or eye disease?

Output: injur y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a kidne y, cerebrovascular or eye disease?. ### Response: injur y.