Instruction: What are some of the other pro-viders involved in the care of patients with ACHD?

Output: obstetricians, pulmonologists, radiologists, nurse practitioners, physician assistants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the other pro-viders involved in the care of patients with ACHD?. ### Response: obstetricians, pulmonologists, radiologists, nurse practitioners, physician assistants.


Instruction: What do patients with ACHD derive their expertise from?

Output: training and/or practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients with ACHD derive their expertise from?. ### Response: training and/or practice.


Instruction: What may individual providers gain ACHD expertise in?

Output: a specific area or discipline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may individual providers gain ACHD expertise in?. ### Response: a specific area or discipline.


Instruction: Who have better outcomes with ACHD?

Output: Patients with ACHD who are undergoing in-vasive cardiovascular procedures in specialized ACHD centers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who have better outcomes with ACHD?. ### Response: Patients with ACHD who are undergoing in-vasive cardiovascular procedures in specialized ACHD centers.


Instruction: What type of care is required to ensure appropriate periprocedural care?

Output: Special attention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care is required to ensure appropriate periprocedural care?. ### Response: Special attention.


Instruction: Where are invasive cardiovascular procedures performed?

Output: specialized ACHD centers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are invasive cardiovascular procedures performed?. ### Response: specialized ACHD centers.


Instruction: Where does Table 6 address delivery of care where circumstances of ACHD expertise may improve patient outcomes?

Output: specialized ACHD centers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does Table 6 address delivery of care where circumstances of ACHD expertise may improve patient outcomes?. ### Response: specialized ACHD centers.


Instruction: What is the most commonly used tool in the evaluation of adults with suspected or known CHD?

Output: Known CHDTools

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most commonly used tool in the evaluation of adults with suspected or known CHD?. ### Response: Known CHDTools.


Instruction: When was E2 JAMA published online?

Output: December 18,2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was E2 JAMA published online?. ### Response: December 18,2013.


Instruction: What is the name of the 2013 American Medical Association publication?

Output: jama.com

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2013 American Medical Association publication?. ### Response: jama.com.


Instruction: Who was John Cuddeback of Kaiser Permanente on 12/18/2013?

Output: John Cuddeback

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was John Cuddeback of Kaiser Permanente on 12/18/2013?. ### Response: John Cuddeback.


Instruction: What is a good practice statement for patients with creatinine clearance of $50 mL/min receivingDOAC therapy for treatment of VTE?

Output: renalfunction monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a good practice statement for patients with creatinine clearance of $50 mL/min receivingDOAC therapy for treatment of VTE?. ### Response: renalfunction monitoring.


Instruction: What is the ASH guideline panelagrees that good practice includes?

Output: recommendations for optimal man-agement of DOAC therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ASH guideline panelagrees that good practice includes?. ### Response: recommendations for optimal man-agement of DOAC therapy.


Instruction: What does the ASH guideline say should be done every 3 months?

Output: renal function monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ASH guideline say should be done every 3 months?. ### Response: renal function monitoring.


Instruction: What is the ungraded good practice statement?

Output: suggesting that health care providers whomanage oral anticoagulation therapy should do so in a systematicand coordinated fashion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ungraded good practice statement?. ### Response: suggesting that health care providers whomanage oral anticoagulation therapy should do so in a systematicand coordinated fashion.


Instruction: What is one of the major differences between the ASH guidelines and the ACCP guidelines?

Output: consistent use of systematic reviews and EtD frameworks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the major differences between the ASH guidelines and the ACCP guidelines?. ### Response: consistent use of systematic reviews and EtD frameworks.


Instruction: What do systematic reviews and EtD frameworks increase?

Output: transparency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do systematic reviews and EtD frameworks increase?. ### Response: transparency.


Instruction: What is used toestimate the relative importance to patients of key outcomes oftreatment?

Output: marker states

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used toestimate the relative importance to patients of key outcomes oftreatment?. ### Response: marker states.


Instruction: What guidelines suggest using longer INR recallintervals for patients receiving VKA therapy during periods of stableINR control?

Output: ASH and ACCP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What guidelines suggest using longer INR recallintervals for patients receiving VKA therapy during periods of stableINR control?. ### Response: ASH and ACCP.


Instruction: Which guidelines make a graded recommendation infavor of using AMS?

Output: ASH guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which guidelines make a graded recommendation infavor of using AMS?. ### Response: ASH guidelines.


Instruction: What was the recommendation in favor of using AMS?

Output: graded

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the recommendation in favor of using AMS?. ### Response: graded.


Instruction: What did ACCP provide an ungraded bestpractice statement?

Output: suggesting that health care providers whomanage oral anticoagulation therapy should do so in a systematicand coordinated fashion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did ACCP provide an ungraded bestpractice statement?. ### Response: suggesting that health care providers whomanage oral anticoagulation therapy should do so in a systematicand coordinated fashion.


Instruction: How should health care providers handle oral anticoagulation therapy?

Output: in a systematicand coordinated fashion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should health care providers handle oral anticoagulation therapy?. ### Response: in a systematicand coordinated fashion.


Instruction: What do both ASH and ACCPguidelines favor over other methods of INR monitoring?

Output: PSM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do both ASH and ACCPguidelines favor over other methods of INR monitoring?. ### Response: PSM.


Instruction: What makes a strong recommendation forPSM?

Output: ASH guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What makes a strong recommendation forPSM?. ### Response: ASH guidelines.


Instruction: Which guidelines make a weak or conditional recommendation favoring PSM?

Output: ACCP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which guidelines make a weak or conditional recommendation favoring PSM?. ### Response: ACCP.


Instruction: What does renal insufficiency mean?

Output: creatinine clearance of ,30 mL/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does renal insufficiency mean?. ### Response: creatinine clearance of ,30 mL/min.


Instruction: What does ACCP recommend over standard doses?

Output: reduced LMWH doses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACCP recommend over standard doses?. ### Response: reduced LMWH doses.


Instruction: The ASHguidelines suggest against using what to adjust LMWH doses in this patient population?

Output: anti –factor Xa monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ASHguidelines suggest against using what to adjust LMWH doses in this patient population?. ### Response: anti –factor Xa monitoring.


Instruction: What should clinicians use to prevent insufficiency?

Output: reduced LMWH doses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should clinicians use to prevent insufficiency?. ### Response: reduced LMWH doses.


Instruction: What do both ASH and ACCP guidelines suggest against administering to patients with INRs between 4.5 and 10.0 and no evidence ofbleeding?

Output: vitamin K

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do both ASH and ACCP guidelines suggest against administering to patients with INRs between 4.5 and 10.0 and no evidence ofbleeding?. ### Response: vitamin K.


Instruction: What is FFP for patients with VKA-associated life-threateningbleeding?

Output: 4-factorPCC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is FFP for patients with VKA-associated life-threateningbleeding?. ### Response: 4-factorPCC.


Instruction: The ASH guidelines include recommendations for optimal man-agement of what?

Output: DOAC therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ASH guidelines include recommendations for optimal man-agement of what?. ### Response: DOAC therapy.


Instruction: What did the ACCP guidelines not include?

Output: DOAC agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ACCP guidelines not include?. ### Response: DOAC agents.


Instruction: When were DOAC agents introduced?

Output: during the time when the ACCPguidelines were being prepared

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were DOAC agents introduced?. ### Response: during the time when the ACCPguidelines were being prepared.


Instruction: What guidelines make a graded suggestion in favor of supplemental patient anticoagulanttherapy education?

Output: ASH guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What guidelines make a graded suggestion in favor of supplemental patient anticoagulanttherapy education?. ### Response: ASH guidelines.


Instruction: What is the name of the systematic review of blood pressure-measuring devices in Tibetan areas of China?

Output: Heart Asia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of blood pressure-measuring devices in Tibetan areas of China?. ### Response: Heart Asia.


Instruction: What is a systematicreview of automaticdigital blood pressure devices?

Output: asystematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematicreview of automaticdigital blood pressure devices?. ### Response: asystematic review and meta-analysis.


Instruction: When did J Hum Hypertens issue 24:431–438.17?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Hum Hypertens issue 24:431–438.17?. ### Response: 2010.


Instruction: What is the name of the systematic review of blood pressure measurement?

Output: Heart Asia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of blood pressure measurement?. ### Response: Heart Asia.


Instruction: What is a national blood pressure measured validated device listing?

Output: BpTRU

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a national blood pressure measured validated device listing?. ### Response: BpTRU.


Instruction: How is blood pressure measured without doctors or nurses present?

Output: Automatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is blood pressure measured without doctors or nurses present?. ### Response: Automatic.


Instruction: Blood PressMonit. 2012;17:96 -102.19.

Output: Automatic of ﬁce bloodpressure measured without doctors or nurses present

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood PressMonit. 2012;17:96 -102.19.. ### Response: Automatic of ﬁce bloodpressure measured without doctors or nurses present.


Instruction: A universal standard for thevalidation of what measuring device?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A universal standard for thevalidation of what measuring device?. ### Response: blood pressure.


Instruction: What is the acronym for Society ofHypertension/International Organization for Standardization?

Output: AAMI/ESH/ISO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Society ofHypertension/International Organization for Standardization?. ### Response: AAMI/ESH/ISO.


Instruction: What is AAMI/ESH/ISO?

Output: A universal standard for thevalidation of blood pressure measuring devices: Association for theAdvancement of Medical Instrumentation/European Society ofHypertension/International Organization for Standardization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AAMI/ESH/ISO?. ### Response: A universal standard for thevalidation of blood pressure measuring devices: Association for theAdvancement of Medical Instrumentation/European Society ofHypertension/International Organization for Standardization.


Instruction: When did JAMA Intern Med publish a collaboration statement?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA Intern Med publish a collaboration statement?. ### Response: 2019.


Instruction: What is the JAMA Intern Med 179:351 –362.21?

Output: A universal standard for thevalidation of blood pressure measuring devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JAMA Intern Med 179:351 –362.21?. ### Response: A universal standard for thevalidation of blood pressure measuring devices.


Instruction: What is a real life setting for attended versus unattended blood pressure measurement?

Output: primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a real life setting for attended versus unattended blood pressure measurement?. ### Response: primary care.


Instruction: What is the difference between using BpTRU and assessments by a trainedtechnician and a clinic nurse?

Output: Automated assessment ofblood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between using BpTRU and assessments by a trainedtechnician and a clinic nurse?. ### Response: Automated assessment ofblood pressure.


Instruction: How many blood pressure measurement methods did Lamarre-Cliche M, Cheong NN, Larochelle P use in hypertensives?

Output: 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many blood pressure measurement methods did Lamarre-Cliche M, Cheong NN, Larochelle P use in hypertensives?. ### Response: 23.


Instruction: What did Myers MG use in routine clinicalpractice?

Output: Automated blood pressure measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Myers MG use in routine clinicalpractice?. ### Response: Automated blood pressure measurement.


Instruction: What does SPRINT stand for?

Output: Systolic Blood Pressure Intervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SPRINT stand for?. ### Response: Systolic Blood Pressure Intervention Trial.


Instruction: What is a comparison between anautomated and manual sphygmomanometer?

Output: a population survey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison between anautomated and manual sphygmomanometer?. ### Response: a population survey.


Instruction: What is the name of the systematic review and meta-analysis of automated blood pressuremeasurement in atrial fibrillation?

Output: asystematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis of automated blood pressuremeasurement in atrial fibrillation?. ### Response: asystematic review.


Instruction: What is the name of the automatic blood pressure measurement device?

Output: Microlife WatchBP Home A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the automatic blood pressure measurement device?. ### Response: Microlife WatchBP Home A.


Instruction: What is Microlife WatchBP Home A used for?

Output: atrial ﬁbrillation screening in a real-world primary care setting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Microlife WatchBP Home A used for?. ### Response: atrial ﬁbrillation screening in a real-world primary care setting.


Instruction: What is the name of the systematic review and meta-analysis of white coat hypertension?

Output: brillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis of white coat hypertension?. ### Response: brillation.


Instruction: What are the names of the authors of this systematic review?

Output: Mingji C, Onakpoya IJ, Heneghan CJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of this systematic review?. ### Response: Mingji C, Onakpoya IJ, Heneghan CJ.


Instruction: How much of the time is needed to manage infection and the sequelae of valve leaflet and paravalvular tissue de-struction?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the time is needed to manage infection and the sequelae of valve leaflet and paravalvular tissue de-struction?. ### Response: 50%.


Instruction: What type of therapy is effective against the specific infective organ-ism?

Output: antimicrobial therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is effective against the specific infective organ-ism?. ### Response: antimicrobial therapy.


Instruction: What is effective against the specific infective organ-ism involved?

Output: antimicrobial therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective against the specific infective organ-ism involved?. ### Response: antimicrobial therapy.


Instruction: What may be nec-sary in patients with septic shock or patients who show high-risk signs on presentation?

Output: Empirical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be nec-sary in patients with septic shock or patients who show high-risk signs on presentation?. ### Response: Empirical therapy.


Instruction: What was the mortality rate before the antibiotic age in IE?

Output: 100%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mortality rate before the antibiotic age in IE?. ### Response: 100%..


Instruction: What has been published by the British Society for Antimicrobial Chemotherapy and the AHA?

Output: Specific antimicrobial regimens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been published by the British Society for Antimicrobial Chemotherapy and the AHA?. ### Response: Specific antimicrobial regimens.


Instruction: What is imperative in antimicrobial sensitivity over time?

Output: concomitant management with the assistance of a consul-tant thoroughly familiar with these patterns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is imperative in antimicrobial sensitivity over time?. ### Response: concomitant management with the assistance of a consul-tant thoroughly familiar with these patterns.


Instruction: What is associated with a significantly higher complexity of care?

Output: Drug use–associated endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with a significantly higher complexity of care?. ### Response: Drug use–associated endocarditis.


Instruction: How much has the incidence of addiction risen in the past decade?

Output: 12-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much has the incidence of addiction risen in the past decade?. ### Response: 12-fold.


Instruction: What is an important part of the Heart Valve Team for this patient pop-ulation?

Output: Addiction specialists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important part of the Heart Valve Team for this patient pop-ulation?. ### Response: Addiction specialists.


Instruction: Addiction studies have shown what?

Output: treat-ment outcomes for behavioral interventions alone for opioid use disorders are dismal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Addiction studies have shown what?. ### Response: treat-ment outcomes for behavioral interventions alone for opioid use disorders are dismal.


Instruction: Addiction studies have shown that treat-ment outcomes for behavioral interventions are what?

Output: dismal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Addiction studies have shown that treat-ment outcomes for behavioral interventions are what?. ### Response: dismal.


Instruction: What percentage of patients return to drug use?

Output: >80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients return to drug use?. ### Response: >80%.


Instruction: Aside from behavioral interventions, what did patients who used pharmacotherapy have a 50% reduction in?

Output: relapse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aside from behavioral interventions, what did patients who used pharmacotherapy have a 50% reduction in?. ### Response: relapse.


Instruction: How much reduction in relapse did behavioral treatments have compared to those who used behavioral therapies alone?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much reduction in relapse did behavioral treatments have compared to those who used behavioral therapies alone?. ### Response: 50%.


Instruction: How many mechanisms can stroke in patients with IE have?

Output: several

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mechanisms can stroke in patients with IE have?. ### Response: several.


Instruction: What is hemorrhagic transfor -mation of an ischemic infarct?

Output: Stroke in patients with IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hemorrhagic transfor -mation of an ischemic infarct?. ### Response: Stroke in patients with IE.


Instruction: What percentage of patients with IE develop clinically evident systemic emboli?

Output: 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with IE develop clinically evident systemic emboli?. ### Response: 35%.


Instruction: What type of tests are used to show a much higher proportion of IE patients?

Output: magnetic resonance imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of tests are used to show a much higher proportion of IE patients?. ### Response: magnetic resonance imaging.


Instruction: How many patients with IE have evidence of emboli?

Output: Up to 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with IE have evidence of emboli?. ### Response: Up to 35%.


Instruction: What is the most common cause of stroke in these patients?

Output: septic embolus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common cause of stroke in these patients?. ### Response: septic embolus.


Instruction: What is heparin resistance after aprotinin?

Output: thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heparin resistance after aprotinin?. ### Response: thrombocytopenia.


Instruction: What is the name of the journal published in 1992?

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal published in 1992?. ### Response: Lancet.


Instruction: 340 ( 8829 ): 1230 - 1231. 93 Albers GW, Atwood JE, Hirsh J, Sherman DG, Hughes RA, Connolly SJ.

Output: 340

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 340 ( 8829 ): 1230 - 1231. 93 Albers GW, Atwood JE, Hirsh J, Sherman DG, Hughes RA, Connolly SJ.. ### Response: 340.


Instruction: What is the name of the study that aimed at preventing stroke in nonvalvular atrial fibrillation?

Output: Ann Intern Med

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that aimed at preventing stroke in nonvalvular atrial fibrillation?. ### Response: Ann Intern Med.


Instruction: What year did Ann Intern Med issue 115 ( 9 ): 727-736?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Intern Med issue 115 ( 9 ): 727-736?. ### Response: 1991.


Instruction: What is contaminated heparin associated with?

Output: Outbreak of adverse reactions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is contaminated heparin associated with?. ### Response: Outbreak of adverse reactions.


Instruction: What is the N Engl J Med. 2008?

Output: Outbreak of adverse reactions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2008?. ### Response: Outbreak of adverse reactions.


Instruction: What year did N Engl J Med publish 359 ( 25 ): 2674 - 2684?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med publish 359 ( 25 ): 2674 - 2684?. ### Response: 2008.


Instruction: What is the name of the chondroitin sulfate?

Output: Oversulfated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the chondroitin sulfate?. ### Response: Oversulfated.


Instruction: What does chondroitin sulfate interact with?

Output: heparin-binding proteins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does chondroitin sulfate interact with?. ### Response: heparin-binding proteins.


Instruction: What are heparin-binding proteins?

Output: new insights into adverse reactions from contaminated heparins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are heparin-binding proteins?. ### Response: new insights into adverse reactions from contaminated heparins.


Instruction: What type of hepatic trans-aminases are elevated after enoxaparin use?

Output: interleukin-11 signaling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hepatic trans-aminases are elevated after enoxaparin use?. ### Response: interleukin-11 signaling.


Instruction: What is the name of the case report and review of unfractionated and low-molecular weight heparin-induced hepatotoxicity?

Output: Pharmacotherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the case report and review of unfractionated and low-molecular weight heparin-induced hepatotoxicity?. ### Response: Pharmacotherapy.


Instruction: What is low-molecular-weight heparin-induced hepatotoxicity?

Output: unfractionated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low-molecular-weight heparin-induced hepatotoxicity?. ### Response: unfractionated.


Instruction: What was a 14-year study of?

Output: heparin-induced thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a 14-year study of?. ### Response: heparin-induced thrombocytopenia.


Instruction: How long did the study of heparin-induced thrombocytopenia last?

Output: 14-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study of heparin-induced thrombocytopenia last?. ### Response: 14-year.


Instruction: What was the name of the study?

Output: Am J Med

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: Am J Med.


Instruction: What enhances interleukin-11 signaling through up-regulation of the MAPK pathway?

Output: Heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What enhances interleukin-11 signaling through up-regulation of the MAPK pathway?. ### Response: Heparin.


Instruction: What does Heparin synergistically enhance?

Output: interleukin-11 signaling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Heparin synergistically enhance?. ### Response: interleukin-11 signaling.


Instruction: What is the name of the antiheparin agent?

Output: Protamine Sulfate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the antiheparin agent?. ### Response: Protamine Sulfate.


Instruction: Where is the American Society of Health-system Pharmacists located?

Output: Bethesda, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the American Society of Health-system Pharmacists located?. ### Response: Bethesda, MD.


Instruction: What is Protamine Sulfate?

Output: Antiheparin Agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Protamine Sulfate?. ### Response: Antiheparin Agents.


Instruction: What is the name of the substance that is used to treat fi sh allergy?

Output: Protamine sulfate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the substance that is used to treat fi sh allergy?. ### Response: Protamine sulfate.


Instruction: How many pages were in the N Engl J Med in 1976?

Output: 295 ( 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages were in the N Engl J Med in 1976?. ### Response: 295 ( 3.


Instruction: How many patients underwent reoperations for valve surgery?

Output: 1,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent reoperations for valve surgery?. ### Response: 1,000.


Instruction: What was the perioperative mortality and determinants of risk for 1,000 patients from 1958-1984?

Output: Reoperations for valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the perioperative mortality and determinants of risk for 1,000 patients from 1958-1984?. ### Response: Reoperations for valve surgery.


Instruction: What was the perioperative mortality and determinants of risk for 1,000 patients, 1958-1984?

Output: Reoperations for valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the perioperative mortality and determinants of risk for 1,000 patients, 1958-1984?. ### Response: Reoperations for valve surgery.


Instruction: What year did Ann Thorac Surg publish its 42 ( 6 ): 632-643?

Output: 1986

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Thorac Surg publish its 42 ( 6 ): 632-643?. ### Response: 1986.


Instruction: What is hexadi-methrine used for after cardiopulmonary bypass?

Output: neutralizing heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hexadi-methrine used for after cardiopulmonary bypass?. ### Response: neutralizing heparin.


Instruction: When was Anaesth Intensive Care published?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Anaesth Intensive Care published?. ### Response: 1999.


Instruction: What is Kikura's name?

Output: M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Kikura's name?. ### Response: M.


Instruction: What is the name of the drug used to neutralize heparin after car-diopulmonary bypass?

Output: vancomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to neutralize heparin after car-diopulmonary bypass?. ### Response: vancomycin.


Instruction: What is another name for hexadimethrine?

Output: vancomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for hexadimethrine?. ### Response: vancomycin.


Instruction: In vitro reversal of what type of cancer?

Output: thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In vitro reversal of what type of cancer?. ### Response: thrombocytopenia.


Instruction: What is the name of the study that showed in vitro reverse of the disease?

Output: American College of Chest Physicians by Kimberly Henricks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that showed in vitro reverse of the disease?. ### Response: American College of Chest Physicians by Kimberly Henricks.


Instruction: What does heparinase do?

Output: reversal of heparin effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does heparinase do?. ### Response: reversal of heparin effect.


Instruction: When was Kimberly Henricks a member of the American College of Chest Physicians?

Output: February 10, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Kimberly Henricks a member of the American College of Chest Physicians?. ### Response: February 10, 2012.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?

Output: March 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?. ### Response: March 2020.


Instruction: What is NPV?

Output: negative predictive values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NPV?. ### Response: negative predictive values.


Instruction: What is AUC?

Output: area under curve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AUC?. ### Response: area under curve.


Instruction: How does AUC compare to white coat HTN?

Output: area under curve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does AUC compare to white coat HTN?. ### Response: area under curve.


Instruction: What type of HTN is undiagnosed?

Output: masked HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of HTN is undiagnosed?. ### Response: masked HTN.


Instruction: What are the key outcomes?

Output: specificity, sensitivity, positive predictive values (PPV), negative predictive values (NPV), area under curve (AUC),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the key outcomes?. ### Response: specificity, sensitivity, positive predictive values (PPV), negative predictive values (NPV), area under curve (AUC),.


Instruction: What is one of the important outcomes of taking medications?

Output: adherence to therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the important outcomes of taking medications?. ### Response: adherence to therapy.


Instruction: What is another important outcome of taking medication?

Output: adherence to therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another important outcome of taking medication?. ### Response: adherence to therapy.


Instruction: What are some of the important outcomes?

Output: specificity, sensitivity, positive predictive values (PPV), negative predictive values (NPV), area under curve (AUC), et c. to diagnose and manage HTN, including white coat HTN, masked HTN, undiagnosed masked HTN  • Key Question 2  ♦ Critical outcomes: Reduction in blood pressure, change in blood pressure from baseline, achievement of lower blood pressure goals, HTN control; adherence to therapy, percentage of patients taking medications  ♦ Important outcomes: composite cardiovascular (CV) outcomes; CV and all- cause mortality; strokes; reduction in CV risks; time to blood pressure control, number of office visits to achieve control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the important outcomes?. ### Response: specificity, sensitivity, positive predictive values (PPV), negative predictive values (NPV), area under curve (AUC), et c. to diagnose and manage HTN, including white coat HTN, masked HTN, undiagnosed masked HTN  • Key Question 2  ♦ Critical outcomes: Reduction in blood pressure, change in blood pressure from baseline, achievement of lower blood pressure goals, HTN control; adherence to therapy, percentage of patients taking medications  ♦ Important outcomes: composite cardiovascular (CV) outcomes; CV and all- cause mortality; strokes; reduction in CV risks; time to blood pressure control, number of office visits to achieve control.


Instruction: What is one of the key questions?

Output: No screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the key questions?. ### Response: No screening.


Instruction: What are the key outcomes of antihypertensive medications?

Output: number of antihypertensive medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the key outcomes of antihypertensive medications?. ### Response: number of antihypertensive medications.


Instruction: What is the key outcome of HTN control?

Output: achievement of lower blood pressure goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the key outcome of HTN control?. ### Response: achievement of lower blood pressure goals.


Instruction: What are the key outcomes of composite CV outcomes?

Output: Reduction in blood pressure, change in blood pressure from  baseline, achievement of lower blood pressure goals, HTN control  ♦ Important outcomes: composite CV outcomes; CV and all -cause mortality; coronary events; strokes; CHF; reduction in CV risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the key outcomes of composite CV outcomes?. ### Response: Reduction in blood pressure, change in blood pressure from  baseline, achievement of lower blood pressure goals, HTN control  ♦ Important outcomes: composite CV outcomes; CV and all -cause mortality; coronary events; strokes; CHF; reduction in CV risks.


Instruction: What is the key outcome of all -cause mortality?

Output: strokes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the key outcome of all -cause mortality?. ### Response: strokes.


Instruction: What are the key outcomes for CV and all- cause mortality?

Output: strokes; reduction in CV risks; time to blood pressure control, number of office visits to achieve control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the key outcomes for CV and all- cause mortality?. ### Response: strokes; reduction in CV risks; time to blood pressure control, number of office visits to achieve control.


Instruction: What is the key outcome for renal function?

Output: safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the key outcome for renal function?. ### Response: safety.


Instruction: How does quality affect two- and three-dimensional echocardiographic determi-nation of left ventricular volumes?

Output: comparison with magnetic resonance imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does quality affect two- and three-dimensional echocardiographic determi-nation of left ventricular volumes?. ### Response: comparison with magnetic resonance imaging.


Instruction: What is a comparison with magnetic resonance imaging?

Output: quality influence two- and three-dimensional echocardiographic determi-nation of left ventricular volumes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison with magnetic resonance imaging?. ### Response: quality influence two- and three-dimensional echocardiographic determi-nation of left ventricular volumes.


Instruction: How does additive value of LV end-systolic measure?

Output: ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does additive value of LV end-systolic measure?. ### Response: ejection fraction.


Instruction: What causes leaflet prolapse?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes leaflet prolapse?. ### Response: Pulmonary hypertension.


Instruction: What is the additive value of left ventricular end-systolic dimension to ejection fraction?

Output: Predicting left ventricular dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the additive value of left ventricular end-systolic dimension to ejection fraction?. ### Response: Predicting left ventricular dysfunction.


Instruction: When did Eur J Echocardiogr. 2011 12:702-10?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Echocardiogr. 2011 12:702-10?. ### Response: 2011.


Instruction: How long did it take to analyze the effects of recurrent mitral regurgitation following mitral valve repair?

Output: long-term

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to analyze the effects of recurrent mitral regurgitation following mitral valve repair?. ### Response: long-term.


Instruction: What are competing outcomes?

Output: early surgery versus con-ventional treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are competing outcomes?. ### Response: early surgery versus con-ventional treatment.


Instruction: What is multimodality imaging for in mitral regurgitation?

Output: patient selection and pro-cedural guidance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is multimodality imaging for in mitral regurgitation?. ### Response: patient selection and pro-cedural guidance.


Instruction: Who developed the guidelines for the evaluation of val-vular regurgitation after percutaneous valve repair or replacement?

Output: American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed the guidelines for the evaluation of val-vular regurgitation after percutaneous valve repair or replacement?. ### Response: American Society of Echocardiography.


Instruction: What was developed in collaboration with the Society for Cardiovascular Aniography and Interventions?

Output: Guidelines for the evaluation of val-vular regurgitation after percutaneous valve repair or replacement: a report from the American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed in collaboration with the Society for Cardiovascular Aniography and Interventions?. ### Response: Guidelines for the evaluation of val-vular regurgitation after percutaneous valve repair or replacement: a report from the American Society of Echocardiography.


Instruction: What does Society for Cardiovascular Magnetic Resonance stand for?

Output: Society for Cardiovascular Angiography and Interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Society for Cardiovascular Magnetic Resonance stand for?. ### Response: Society for Cardiovascular Angiography and Interventions.


Instruction: What is the J Am Soc Echocardiogr. 2019;32:431–75.7.2.2.2?

Output: Diagnostic Testing: Changing Signs or Symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Soc Echocardiogr. 2019;32:431–75.7.2.2.2?. ### Response: Diagnostic Testing: Changing Signs or Symptoms.


Instruction: Who is Antoine C, Benfari G, Michelena HI?

Output: Antoine C, Benfari G, Michelena HI, et al. Clinical outcome of degenera-tive mitral regurgitation: critical importance of echocardiographic quanti-tative assessment in routine practice. Circulation. 2018;138:1317–26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Antoine C, Benfari G, Michelena HI?. ### Response: Antoine C, Benfari G, Michelena HI, et al. Clinical outcome of degenera-tive mitral regurgitation: critical importance of echocardiographic quanti-tative assessment in routine practice. Circulation. 2018;138:1317–26.


Instruction: What is the role of preop-erative symptoms on survival after surgical correction of organic mitral regurgitation?

Output: rationale for optimizing surgical indications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of preop-erative symptoms on survival after surgical correction of organic mitral regurgitation?. ### Response: rationale for optimizing surgical indications.


Instruction: What is Routine Follow-Up?

Output: Diagnostic Testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Routine Follow-Up?. ### Response: Diagnostic Testing.


Instruction: What affects short- and long-term survival after mitral valve operation for mitral regurgitation?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What affects short- and long-term survival after mitral valve operation for mitral regurgitation?. ### Response: Pulmonary hypertension.


Instruction: What does Pulmonary hypertension ad-verse affect?

Output: short- and long-term survival after mitral valve operation for mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Pulmonary hypertension ad-verse affect?. ### Response: short- and long-term survival after mitral valve operation for mitral regurgitation.


Instruction: What is the purpose of mitral valve operation for mitral regurgitation?

Output: timing of surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of mitral valve operation for mitral regurgitation?. ### Response: timing of surgery.


Instruction: What are implications for timing of surgery?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implications for timing of surgery?. ### Response: Pulmonary hypertension.


Instruction: When was J Thorac Car-diovasc Surg. 2011;142:1439–52?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was J Thorac Car-diovasc Surg. 2011;142:1439–52?. ### Response: 2011.


Instruction: What is the difference between early surgery and conventional treatment in asymptomatic severe mitral regurgitation?

Output: Comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between early surgery and conventional treatment in asymptomatic severe mitral regurgitation?. ### Response: Comparison.


Instruction: What is Bonow RO's specialty?

Output: Chronic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Bonow RO's specialty?. ### Response: Chronic.


Instruction: What was the name of the study?

Output: American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: American Society of Echocardiography.


Instruction: What did Avierinos J-F, Messika-Zeitoun D, and Enriquez-Sarano do?

Output: surgical correction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Avierinos J-F, Messika-Zeitoun D, and Enriquez-Sarano do?. ### Response: surgical correction.


Instruction: What are complications and their relationships with surrounding struc-tures?

Output: exposure to radiation, nephrotoxicity associated with contrast dye, and relative lack of sensitivity in 1 study to demonstrate valve perforations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are complications and their relationships with surrounding struc-tures?. ### Response: exposure to radiation, nephrotoxicity associated with contrast dye, and relative lack of sensitivity in 1 study to demonstrate valve perforations.


Instruction: What leads to an overestimation of vegetation size and challenging visualization of fast-moving structures?

Output: lower temporal and lateral resolu-tion with 3D echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What leads to an overestimation of vegetation size and challenging visualization of fast-moving structures?. ### Response: lower temporal and lateral resolu-tion with 3D echocardiography.


Instruction: What can be used to evaluate great vessels and coronary artery disease?

Output: cardiac CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to evaluate great vessels and coronary artery disease?. ### Response: cardiac CT.


Instruction: What is not secured with TEE in cases of IE?

Output: definitive evidence of IE and its complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not secured with TEE in cases of IE?. ### Response: definitive evidence of IE and its complications.


Instruction: How can CT angiography be used?

Output: coronary artery evalu-ation in patients who are to undergo cardiac surgery for IE complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can CT angiography be used?. ### Response: coronary artery evalu-ation in patients who are to undergo cardiac surgery for IE complications.


Instruction: What type of evalu-ation may be useful in head-to-toe preoperative screening?

Output: coronary CT angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of evalu-ation may be useful in head-to-toe preoperative screening?. ### Response: coronary CT angiography.


Instruction: What is an example of an intra-abdominal lesions?

Output: silent splenic abscesses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an intra-abdominal lesions?. ### Response: silent splenic abscesses.


Instruction: What has had a major impact on IE diagnosis and manage-ment?

Output: 67MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has had a major impact on IE diagnosis and manage-ment?. ### Response: 67MRI.


Instruction: What is MRI used to detect?

Output: cerebral embolic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MRI used to detect?. ### Response: cerebral embolic events.


Instruction: What can detect cerebral embolic events?

Output: MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can detect cerebral embolic events?. ### Response: MRI.


Instruction: What are not well established in IE management?

Output: Indications for the rou-tine use of MRI and magnetic resonance angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are not well established in IE management?. ### Response: Indications for the rou-tine use of MRI and magnetic resonance angiography.


Instruction: What is needed to define the utility of 18F-fluoro-deoxyglucose positron emission tomography/CT in the diag-nosis and management of IE?

Output: More study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to define the utility of 18F-fluoro-deoxyglucose positron emission tomography/CT in the diag-nosis and management of IE?. ### Response: More study.


Instruction: In a prospective study of 25 IE cases, what was useful in identifying peripheral embolization in 11 patients and in detecting IE extracardiac?

Output: 18F-fluorodeoxyglucose positron emission tomography/CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a prospective study of 25 IE cases, what was useful in identifying peripheral embolization in 11 patients and in detecting IE extracardiac?. ### Response: 18F-fluorodeoxyglucose positron emission tomography/CT.


Instruction: In how many patients did peripheral embolization occur?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In how many patients did peripheral embolization occur?. ### Response: 11.


Instruction: In 7 patients who did not demonstrate any clinical manifestations of IE, what was detected?

Output: IE extracardiac manifestations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 7 patients who did not demonstrate any clinical manifestations of IE, what was detected?. ### Response: IE extracardiac manifestations.


Instruction: The use of multimodality imaging in IE may increase in the future as the risks and benefits of each diagnostic tool are defined?

Output: 70

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The use of multimodality imaging in IE may increase in the future as the risks and benefits of each diagnostic tool are defined?. ### Response: 70.


Instruction: What are the clinical and echocardiographic features that suggest potential need for surgical intervention?

Output: Vegetation Persistent vegetation after systemic embolization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinical and echocardiographic features that suggest potential need for surgical intervention?. ### Response: Vegetation Persistent vegetation after systemic embolization.


Instruction: What type of vegetation persists after systemic embolization?

Output: Anterior mitral leaflet vegetation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of vegetation persists after systemic embolization?. ### Response: Anterior mitral leaflet vegetation.


Instruction: Antimicrobial therapy increases vegetation size despite what?

Output: appropriate antimicrobial therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antimicrobial therapy increases vegetation size despite what?. ### Response: appropriate antimicrobial therapy.


Instruction: Valvular dysfunction Acute aortic or mitral insufficiency with signs of what type of failure?

Output: ventricular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Valvular dysfunction Acute aortic or mitral insufficiency with signs of what type of failure?. ### Response: ventricular.


Instruction: Heart failure unresponsive to what kind of therapy?

Output: medical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Heart failure unresponsive to what kind of therapy?. ### Response: medical.


Instruction: Perivalvular extension Valve dehiscence, rupture, or fistula?

Output: perforations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Perivalvular extension Valve dehiscence, rupture, or fistula?. ### Response: perforations.


Instruction: What may be required because of risk of embolization?

Output: Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be required because of risk of embolization?. ### Response: Surgery.


Instruction: How many exomes did the ACMG guidelines integrate?

Output: 60 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many exomes did the ACMG guidelines integrate?. ### Response: 60 000.


Instruction: What is the role of catecholamin-ergic polymorphic ventricular tachycardia-associated variants?

Output: Integration of 60 000 exomes and ACMG guidelines question

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of catecholamin-ergic polymorphic ventricular tachycardia-associated variants?. ### Response: Integration of 60 000 exomes and ACMG guidelines question.


Instruction: When did the J Am Coll Cardiol. 2009 issue 54:832-7?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol. 2009 issue 54:832-7?. ### Response: 2009.


Instruction: What type of variants are associated with ventricular tachycardia?

Output: catecholamin-ergic polymorphic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of variants are associated with ventricular tachycardia?. ### Response: catecholamin-ergic polymorphic.


Instruction: What is the name of the 2017 issue of Clin Genet?

Output: 91:63–72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2017 issue of Clin Genet?. ### Response: 91:63–72.


Instruction: Who is the author of Long-term follow-up of patients with short QT syndrome?

Output: Giustetto C, Schimpf R, Mazzanti A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Long-term follow-up of patients with short QT syndrome?. ### Response: Giustetto C, Schimpf R, Mazzanti A.


Instruction: When was the J Am Coll Cardiol published?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol published?. ### Response: 2007.


Instruction: What are electrophysiological studies in predicting risk of ventricular arrhythmia in early repolarization syndrome?

Output: Role of electrophysiological stud-ies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are electrophysiological studies in predicting risk of ventricular arrhythmia in early repolarization syndrome?. ### Response: Role of electrophysiological stud-ies.


Instruction: What is the J Am Coll Cardiol. 2015;65:151-9?

Output: S7.9-27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2015;65:151-9?. ### Response: S7.9-27.


Instruction: What is the strongest predictor of arrhythmia recurrence in patients with idiopathic ventricular fibrillation?

Output: Early repolarization pat-tern

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strongest predictor of arrhythmia recurrence in patients with idiopathic ventricular fibrillation?. ### Response: Early repolarization pat-tern.


Instruction: How long did a single centre long-term follow-up over 20 years take?

Output: 18:718–25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did a single centre long-term follow-up over 20 years take?. ### Response: 18:718–25.


Instruction: What is a congenital long QT syndrome?

Output: a single-cen-ter experience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a congenital long QT syndrome?. ### Response: a single-cen-ter experience.


Instruction: What is an implantable cardioverter defibrillator therapy for?

Output: congenital long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an implantable cardioverter defibrillator therapy for?. ### Response: congenital long QT syndrome.


Instruction: When was the J Am Coll Cardiol 50:1335–40?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 50:1335–40?. ### Response: 2007.


Instruction: What is a long QT syndrome?

Output: beta-blockers and continuous pacing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a long QT syndrome?. ### Response: beta-blockers and continuous pacing.


Instruction: What year did data from the Italian ICD Registry come from?

Output: 2001–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did data from the Italian ICD Registry come from?. ### Response: 2001–.


Instruction: What is the name of the clinic that treats inherited arrhythmia?

Output: spe-cialized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the clinic that treats inherited arrhythmia?. ### Response: spe-cialized.


Instruction: How long did it take to implant a cardioverter-defi-brillator in Brugada syndrome?

Output: 20-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to implant a cardioverter-defi-brillator in Brugada syndrome?. ### Response: 20-year.


Instruction: What was the outcome of a spe-cialized arrhythmic clinic?

Output: Patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of a spe-cialized arrhythmic clinic?. ### Response: Patient.


Instruction: What is the name of the systematic review and meta-analysis of inappropriate shocks and complications of implantable cardioverter-defibrillator harm in young patients with inherited arrhythmia syndromes?

Output: Olde Nordkamp LR, Postema PG, Knops RE, et al. Implantable cardioverter-defibrillator harm in young patients with inherited arrhythmia syndromes: a systematic review and meta-analysis of inappropriate shocks and complications. Heart Rhythm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis of inappropriate shocks and complications of implantable cardioverter-defibrillator harm in young patients with inherited arrhythmia syndromes?. ### Response: Olde Nordkamp LR, Postema PG, Knops RE, et al. Implantable cardioverter-defibrillator harm in young patients with inherited arrhythmia syndromes: a systematic review and meta-analysis of inappropriate shocks and complications. Heart Rhythm.


Instruction: What is a monomorphic ventricular tachycardia?

Output: patients with Brugada syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a monomorphic ventricular tachycardia?. ### Response: patients with Brugada syndrome.


Instruction: What type of ventricular tachycardia is found in patients with Brugada syndrome?

Output: Monomorphic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of ventricular tachycardia is found in patients with Brugada syndrome?. ### Response: Monomorphic.


Instruction: What is the name of the multicenter Israeli study that evaluated the outcome after implantation of a cardioverter defibrillator?

Output: ISRABRU

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter Israeli study that evaluated the outcome after implantation of a cardioverter defibrillator?. ### Response: ISRABRU.


Instruction: What is ISRABRU?

Output: multicenter Israeli study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ISRABRU?. ### Response: multicenter Israeli study.


Instruction: What is the name of the multicenter Israeli study?

Output: ISRABRU

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter Israeli study?. ### Response: ISRABRU.


Instruction: How many patients were treated with beta-blockers?

Output: 20-year single-center experience. J Am Coll Cardiol. 2015;65:879–88. S7.9-34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with beta-blockers?. ### Response: 20-year single-center experience. J Am Coll Cardiol. 2015;65:879–88. S7.9-34.


Instruction: What is the name of the organization that provides a summary of recommendations and practice points for physical activity interventions?

Output: kidney-international.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that provides a summary of recommendations and practice points for physical activity interventions?. ### Response: kidney-international.org.


Instruction: What is the acronym for the National Cholesterol Education Program Adult Treatment Panel III?

Output: 0000133317

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the National Cholesterol Education Program Adult Treatment Panel III?. ### Response: 0000133317.


Instruction: What is the name of the guidelines for the National Cholesterol Education Program Adult Treatment Panel III?

Output: clinical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guidelines for the National Cholesterol Education Program Adult Treatment Panel III?. ### Response: clinical trials.


Instruction: What is a risk modifier for HDL-C?

Output: role

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk modifier for HDL-C?. ### Response: role.


Instruction: Who is the AIM-HIGH Investigator?

Output: Boden WE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the AIM-HIGH Investigator?. ### Response: Boden WE.


Instruction: What is niacin used for in patients with low HDL cholesterol levels?

Output: intensive statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is niacin used for in patients with low HDL cholesterol levels?. ### Response: intensive statin therapy.


Instruction: What is the name of the drug that is used to treat low cholesterol?

Output: Niacin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat low cholesterol?. ### Response: Niacin.


Instruction: When did N Engl J Med issue 365:2255-2267?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 365:2255-2267?. ### Response: 2011.


Instruction: What does ezetimibe do for carotid intima-media thickness?

Output: Extended-release niacin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ezetimibe do for carotid intima-media thickness?. ### Response: Extended-release niacin.


Instruction: When was niacin released?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was niacin released?. ### Response: 2009.


Instruction: What is the NEJMoa0907569?

Output: 10.1056

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NEJMoa0907569?. ### Response: 10.1056.


Instruction: What is the name of the investigators that investigated the effects of torcetrapib in patients at high risk for coro-nary events?

Output: ILLUMINATE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the investigators that investigated the effects of torcetrapib in patients at high risk for coro-nary events?. ### Response: ILLUMINATE.


Instruction: What was the N Engl J Med 2007357:2109–2122?

Output: Effects of torcetrapib

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med 2007357:2109–2122?. ### Response: Effects of torcetrapib.


Instruction: What is the name of the meta-analysis of randomized controlled trials of high-density lipoprotein cholesterol-increasing compounds?

Output: Efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of randomized controlled trials of high-density lipoprotein cholesterol-increasing compounds?. ### Response: Efficacy and safety.


Instruction: What are the names of the two compounds that have been shown to increase cholesterol?

Output: high-density lipoprotein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the two compounds that have been shown to increase cholesterol?. ### Response: high-density lipoprotein.


Instruction: Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease?

Output: ezetimibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease?. ### Response: ezetimibe.


Instruction: N Engl J Med. 2001;345:1583–1592. doi: 10.1056/NEJMoa011090.

Output: Simvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: N Engl J Med. 2001;345:1583–1592. doi: 10.1056/NEJMoa011090.. ### Response: Simvastatin.


Instruction: What is the Framington study?

Output: Predicting coronary heart disease in middle-aged and older persons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Framington study?. ### Response: Predicting coronary heart disease in middle-aged and older persons.


Instruction: What are the lipids in coronary heart disease called?

Output: lipoprotein cholesterol lev-els

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the lipids in coronary heart disease called?. ### Response: lipoprotein cholesterol lev-els.


Instruction: What did the Cooperative Lipoprotein Phenotyping Study do?

Output: Predicting coronary heart disease in middle-aged and older persons: the Framington study. JAMA. 1977;238:497–499. 149. Castelli WP, Doyle JT, Gordon T, Hames CG, Hjortland MC, Hulley SB, Kagan A, Zukel WJ. HDL cholesterol and other lipids in coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Cooperative Lipoprotein Phenotyping Study do?. ### Response: Predicting coronary heart disease in middle-aged and older persons: the Framington study. JAMA. 1977;238:497–499. 149. Castelli WP, Doyle JT, Gordon T, Hames CG, Hjortland MC, Hulley SB, Kagan A, Zukel WJ. HDL cholesterol and other lipids in coronary heart disease.


Instruction: What was the name of the study that examined the incidence of coronary heart disease and lipoprotein cholesterol?

Output: Framingham Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that examined the incidence of coronary heart disease and lipoprotein cholesterol?. ### Response: Framingham Study.


Instruction: When was the Framingham Study published?

Output: 1986

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Framingham Study published?. ### Response: 1986.


Instruction: What type of cholesterol is associated with cardiovascular events?

Output: HDL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of cholesterol is associated with cardiovascular events?. ### Response: HDL.


Instruction: What is the N Engl J Med 2007357:1301-1310?

Output: HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med 2007357:1301-1310?. ### Response: HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events.


Instruction: Who is EH, Koh YS, Park MW, Shin DI, Choi JS, Kim HJ, Kim JJ, Park HJ?

Output: Seo SM, Choo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is EH, Koh YS, Park MW, Shin DI, Choi JS, Kim HJ, Kim JJ, Park HJ?. ### Response: Seo SM, Choo.


Instruction: Who is Shin DI?

Output: Choi YS, Park HJ, Kim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Shin DI?. ### Response: Choi YS, Park HJ, Kim.


Instruction: What is the name of the device used in a US myotonic dystrophy type 1 popula-tion?

Output: Pacemaker and implantable cardio-verter-defibrillator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the device used in a US myotonic dystrophy type 1 popula-tion?. ### Response: Pacemaker and implantable cardio-verter-defibrillator.


Instruction: When was the J Cardiovasc Electrophysiol. 2011:22:1369–75?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Cardiovasc Electrophysiol. 2011:22:1369–75?. ### Response: 2011.


Instruction: What does Laurent V, Pellieux S, Corcia P, et al. discuss in the area of prophylactic pacing devices?

Output: Mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Laurent V, Pellieux S, Corcia P, et al. discuss in the area of prophylactic pacing devices?. ### Response: Mortality.


Instruction: What are patients in the area of?

Output: myotonic dystrophy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients in the area of?. ### Response: myotonic dystrophy.


Instruction: Int J Cardiol. 2011;150:54–8. S7.8-15. Groh WJ. What are arrhythmias in the muscular dystrophies?

Output: Arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol. 2011;150:54–8. S7.8-15. Groh WJ. What are arrhythmias in the muscular dystrophies?. ### Response: Arrhythmias.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines develop in collaboration with the American Association for Thoracic Surgery?

Output: hythmia Devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines develop in collaboration with the American Association for Thoracic Surgery?. ### Response: hythmia Devices.


Instruction: What was the name of the Task Force to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices?

Output: Writing Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the Task Force to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices?. ### Response: Writing Committee.


Instruction: What is the acronym for American Association for Thoracic Surgery?

Output: Society of Thoracic Surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American Association for Thoracic Surgery?. ### Response: Society of Thoracic Surgeons.


Instruction: What are the names of the organizations that are involved in the long-term follow-up of patients?

Output: American Association for Thoracic Surgery and Society of Thoracic Surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the organizations that are involved in the long-term follow-up of patients?. ### Response: American Association for Thoracic Surgery and Society of Thoracic Surgeons.


Instruction: What is not necessary for long-term follow-up of patients with myotonic dystrophy?

Output: an electrocardiogram

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not necessary for long-term follow-up of patients with myotonic dystrophy?. ### Response: an electrocardiogram.


Instruction: What is a trio-ventricular conduction disease?

Output: catecholaminergic polymorphic ventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a trio-ventricular conduction disease?. ### Response: catecholaminergic polymorphic ventricular tachycardia.


Instruction: How many years is an electrocardiogram not necessary?

Output: every year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years is an electrocardiogram not necessary?. ### Response: every year.


Instruction: I and II Pacing. Orthop Electrophysiol. 2012;35:1262–9.7.9. Cardiac Channelopathies S7.9-1. Bai R, Napolitano C, Bloise R, et al. Yield of genetic screening in inherited cardiac channelopathies: how to prioritize access to genetic testing?

Output: Clin Electrophysiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: I and II Pacing. Orthop Electrophysiol. 2012;35:1262–9.7.9. Cardiac Channelopathies S7.9-1. Bai R, Napolitano C, Bloise R, et al. Yield of genetic screening in inherited cardiac channelopathies: how to prioritize access to genetic testing?. ### Response: Clin Electrophysiol.


Instruction: What is the risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syn-drome and normal-range corrected QT intervals?

Output: Risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syn-drome and normal-range corrected QT intervals?. ### Response: Risk.


Instruction: When did Horr S, Moss AJ, and Dijksman LM die?

Output: S7.8-13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Horr S, Moss AJ, and Dijksman LM die?. ### Response: S7.8-13.


Instruction: What is the name of the registry used for risk stratification in Brugada syndrome?

Output: PRELUDE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry used for risk stratification in Brugada syndrome?. ### Response: PRELUDE.


Instruction: What does PRELUDE stand for?

Output: PRogrammed ELectrical stimUlation preDictive valuE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PRELUDE stand for?. ### Response: PRogrammed ELectrical stimUlation preDictive valuE.


Instruction: When was the J Am Coll Cardiol. 2012?

Output: 59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol. 2012?. ### Response: 59.


Instruction: What type of ventricular tachycardia does Priori SG, Napolitano C, Memmi M, et al. have?

Output: catecholaminergic polymorphic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of ventricular tachycardia does Priori SG, Napolitano C, Memmi M, et al. have?. ### Response: catecholaminergic polymorphic.


Instruction: What is the name of the study that Wilde AA, Moss AJ, Kaufman ES did?

Output: international multicenter study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that Wilde AA, Moss AJ, Kaufman ES did?. ### Response: international multicenter study.


Instruction: When was this study published?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 23, 2023.


Instruction: What is the name of the multicenter study?

Output: type 3 long-QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter study?. ### Response: type 3 long-QT syndrome.


Instruction: What is a hallmark of circulat-ing microRNAs in patients with acute heart failure?

Output: Metabolic disturbances

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a hallmark of circulat-ing microRNAs in patients with acute heart failure?. ### Response: Metabolic disturbances.


Instruction: What is another name for Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardio-vascular diseases?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardio-vascular diseases?. ### Response: Circulation.


Instruction: What are two aspects of cardio-vascular diseases related to?

Output: form and function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two aspects of cardio-vascular diseases related to?. ### Response: form and function.


Instruction: What is the name of the journal that studies the relationship between metabolic disturbances in plasma and heart failure?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the relationship between metabolic disturbances in plasma and heart failure?. ### Response: J Am Coll Cardiol.


Instruction: In what year was Circulation 126:1110-20?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was Circulation 126:1110-20?. ### Response: 2012.


Instruction: What is the ARIC Study?

Output: Associations between metabolomic compounds and incident heart failure among African Americans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ARIC Study?. ### Response: Associations between metabolomic compounds and incident heart failure among African Americans.


Instruction: What are the associations between metabolomic compounds and incident heart failure among African Americans?

Output: the ARIC Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the associations between metabolomic compounds and incident heart failure among African Americans?. ### Response: the ARIC Study.


Instruction: What is the effect of spironolactone added to an angiotensin converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure?

Output: Effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of spironolactone added to an angiotensin converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure?. ### Response: Effectiveness.


Instruction: What was the Randomized Aldactone Evaluation Study?

Output: Effectiveness of spironolactone added to an angiotensin -converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Randomized Aldactone Evaluation Study?. ### Response: Effectiveness of spironolactone added to an angiotensin -converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure.


Instruction: What type of care programme is feasible for elderly patients with moderate to severe heart failure?

Output: nurse -monitored, outpatient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care programme is feasible for elderly patients with moderate to severe heart failure?. ### Response: nurse -monitored, outpatient.


Instruction: What journal did Ekman I, Fagerberg B, Matejka G, and Persson B write about in 1998?

Output: European Heart Journal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What journal did Ekman I, Fagerberg B, Matejka G, and Persson B write about in 1998?. ### Response: European Heart Journal.


Instruction: What is an angiotensin-converting enzyme inhibitor used for?

Output: severe chronic congestive heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an angiotensin-converting enzyme inhibitor used for?. ### Response: severe chronic congestive heart failure.


Instruction: What is a key feature of many chronic rheumatologic inflam-matory joint disorders?

Output: systemic lupus ery-thematosus, RA, and psoriasis.S4.5.5-1 Inflammation mediates the progression of atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key feature of many chronic rheumatologic inflam-matory joint disorders?. ### Response: systemic lupus ery-thematosus, RA, and psoriasis.S4.5.5-1 Inflammation mediates the progression of atherosclerosis.


Instruction: Inflammation mediates the progression of what?

Output: atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inflammation mediates the progression of what?. ### Response: atherosclerosis.


Instruction: What is the risk of MI among individu-als with RA?

Output: similar to that of an adult with diabetes mel-litus or one who is about 10 years older without RA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of MI among individu-als with RA?. ### Response: similar to that of an adult with diabetes mel-litus or one who is about 10 years older without RA.


Instruction: What is the risk of CVD death for people with RA?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of CVD death for people with RA?. ### Response: 50%.