Instruction: What are normal and abnormal lipid values in childhood?

Output: Acceptable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are normal and abnormal lipid values in childhood?. ### Response: Acceptable.


Instruction: How many mmol/L?

Output: 2.8–3.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mmol/L?. ### Response: 2.8–3.3.


Instruction: What is the ratio of non-HDL-C?

Output: <120

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ratio of non-HDL-C?. ### Response: <120.


Instruction: What are the values given in mg/dL?

Output: <170

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the values given in mg/dL?. ### Response: <170.


Instruction: To convert to SI units, divide the results for TC, LDL-C, and non-HDL-C by what?

Output: 38.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To convert to SI units, divide the results for TC, LDL-C, and non-HDL-C by what?. ### Response: 38.6.


Instruction: For triglycerides, divide by 88.6.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For triglycerides, divide by 88.6.. ### Response: .*.


Instruction: What is the NCEP Expert Panel on Cholesterol Levels in Children?

Output: plasma lipid and lipoprotein levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NCEP Expert Panel on Cholesterol Levels in Children?. ### Response: plasma lipid and lipoprotein levels.


Instruction: What are the non-HDL-C values from the Bogalusa Heart Study equivalent to?

Output: mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the non-HDL-C values from the Bogalusa Heart Study equivalent to?. ### Response: mg/dL.


Instruction: The low cutpoints for high and borderline high represent approximately what percentiles?

Output: 95th and 75th

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The low cutpoints for high and borderline high represent approximately what percentiles?. ### Response: 95th and 75th.


Instruction: What are the cutpoints for HDL-C?

Output: >45

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the cutpoints for HDL-C?. ### Response: >45.


Instruction: What is the low cutpoint for LDL-C called?

Output: >45

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the low cutpoint for LDL-C called?. ### Response: >45.


Instruction: How many percentiles of HDL are there?

Output: >45

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many percentiles of HDL are there?. ### Response: >45.


Instruction: What did Mathiesen ER, Hommel E, Giese J, et al. do in postponing nephropathy in normotensive insulin dependent diabeticpatients with microalbuminuria?

Output: captopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Mathiesen ER, Hommel E, Giese J, et al. do in postponing nephropathy in normotensive insulin dependent diabeticpatients with microalbuminuria?. ### Response: captopril.


Instruction: What did Mauer M, Zinman B, Gardiner R do in type 1 diabetes?

Output: Renal and retinal effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Mauer M, Zinman B, Gardiner R do in type 1 diabetes?. ### Response: Renal and retinal effects.


Instruction: What type of diabetes is perindopril used for?

Output: microalbuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes is perindopril used for?. ### Response: microalbuminuria.


Instruction: What is the effect of captopril on blood pressure?

Output: kidney function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of captopril on blood pressure?. ### Response: kidney function.


Instruction: How long was the study conducted?

Output: 3-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the study conducted?. ### Response: 3-year.


Instruction: What does captopril do to blood pressure and kidney function in normotensive insulin dependent diabetics with nephropathy?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does captopril do to blood pressure and kidney function in normotensive insulin dependent diabetics with nephropathy?. ### Response: Effect.


Instruction: When did BMJ issue 299:533-536?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did BMJ issue 299:533-536?. ### Response: 1989.


Instruction: What did Damkjaer Nielsen M, et al. do?

Output: Effect of captopril onblood pressure and kidney function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Damkjaer Nielsen M, et al. do?. ### Response: Effect of captopril onblood pressure and kidney function.


Instruction: What may be reason-able in patients less than or equal to 60 years of age?

Output: Complete arterial revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reason-able in patients less than or equal to 60 years of age?. ### Response: Complete arterial revascularization.


Instruction: Arterial grafting of the right coronary artery may bereasonable when a critical (>90%) stenosis is pres-ent?

Output: 89

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arterial grafting of the right coronary artery may bereasonable when a critical (>90%) stenosis is pres-ent?. ### Response: 89.


Instruction: What percentage of stenosis is pres-ent?

Output: >90%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of stenosis is pres-ent?. ### Response: >90%).


Instruction: What type of artery graft may be reasonable when grafting left-sided coronary arteries with severestenoses?

Output: radial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of artery graft may be reasonable when grafting left-sided coronary arteries with severestenoses?. ### Response: radial.


Instruction: How much of a criti-cal stenose is present in right-sided arteries?

Output: >90%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of a criti-cal stenose is present in right-sided arteries?. ### Response: >90%).


Instruction: What is class III: HARM1?

Output: >90%) that perfuse LV myocardi-um

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is class III: HARM1?. ### Response: >90%) that perfuse LV myocardi-um.


Instruction: What should not be used to bypass the right coronary artery with less than a critical steno-sis?

Output: An arterial graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be used to bypass the right coronary artery with less than a critical steno-sis?. ### Response: An arterial graft.


Instruction: Arteries (internal mammary, radial, gastroepiploic, and infe-rior epigastric) or veins may be used as what?

Output: conduits for CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arteries (internal mammary, radial, gastroepiploic, and infe-rior epigastric) or veins may be used as what?. ### Response: conduits for CABG.


Instruction: What are conduits for CABG?

Output: Arteries (internal mammary, radial, gastroepiploic, and infe-rior epigastric) or veins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are conduits for CABG?. ### Response: Arteries (internal mammary, radial, gastroepiploic, and infe-rior epigastric) or veins.


Instruction: The effectiveness of CABG in relieving symptoms and prolonging life is directly related to what?

Output: graft patency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The effectiveness of CABG in relieving symptoms and prolonging life is directly related to what?. ### Response: graft patency.


Instruction: Because arterial and venous grafts have differ-ent patency rates and modes of failure, conduit selection is important in determining the long-term efficacy of what procedure?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Because arterial and venous grafts have differ-ent patency rates and modes of failure, conduit selection is important in determining the long-term efficacy of what procedure?. ### Response: CABG.


Instruction: What is another name for reversed saphenous vein grafts?

Output: Saphenous Vein Grafts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for reversed saphenous vein grafts?. ### Response: Saphenous Vein Grafts.


Instruction: What is the disadvantage of SVGs in CABG?

Output: de-clining patency with time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the disadvantage of SVGs in CABG?. ### Response: de-clining patency with time.


Instruction: How many patients occlude within 1 year of CABG89,102,103?

Output: 10% to as many as 25%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients occlude within 1 year of CABG89,102,103?. ### Response: 10% to as many as 25%.


Instruction: During the 1 to 5 years after CABG, what percentage of patientsocclude each year?

Output: 1% to2%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: During the 1 to 5 years after CABG, what percentage of patientsocclude each year?. ### Response: 1% to2%.


Instruction: What percentage of SVGs are patent 10 years after CABG?

Output: 50% to60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of SVGs are patent 10 years after CABG?. ### Response: 50% to60%.


Instruction: How long after surgery does occlude occur?

Output: 1 to 5 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after surgery does occlude occur?. ### Response: 1 to 5 years.


Instruction: What percentage have noangiographic evidence of atherosclerosis?

Output: half

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage have noangiographic evidence of atherosclerosis?. ### Response: half.


Instruction: What happens to the endo-thelium during SVGharvesting and initial exposure to arterial pressure?

Output: damaged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What happens to the endo-thelium during SVGharvesting and initial exposure to arterial pressure?. ### Response: damaged.


Instruction: What can lead to platelet aggregation and graft thrombosis?

Output: the endo-thelium often is damaged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can lead to platelet aggregation and graft thrombosis?. ### Response: the endo-thelium often is damaged.


Instruction: The process of intimal hyperplasia that causes SVG atherosclerosis is called what?

Output: intima

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The process of intimal hyperplasia that causes SVG atherosclerosis is called what?. ### Response: intima.


Instruction: What release mitogens that stimulate smooth muscle cell migration?

Output: platelets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What release mitogens that stimulate smooth muscle cell migration?. ### Response: platelets.


Instruction: What is incorporated into these areas of intimal hyperplasia?

Output: Lipid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is incorporated into these areas of intimal hyperplasia?. ### Response: Lipid.


Instruction: How long does the perioperative administration of aspirin and dipyr-idamole improve?

Output: /H110211 month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does the perioperative administration of aspirin and dipyr-idamole improve?. ### Response: /H110211 month.


Instruction: What decreases lipid accumulation in the SVG intima?

Output: The perioperative administration of aspirin and dipyr-idamole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What decreases lipid accumulation in the SVG intima?. ### Response: The perioperative administration of aspirin and dipyr-idamole.


Instruction: Why are IMAs usually patent for many yearspostoperatively?

Output: the fact that /H110214% of IMAs develop atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are IMAs usually patent for many yearspostoperatively?. ### Response: the fact that /H110214% of IMAs develop atherosclerosis.


Instruction: What percentage of IMA's develop atherosclerosis?

Output: /H110214%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of IMA's develop atherosclerosis?. ### Response: /H110214%.


Instruction: What are the ACC/AHA2006 guidelines for the management of patients?

Output: valvular heartdisease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the ACC/AHA2006 guidelines for the management of patients?. ### Response: valvular heartdisease.


Instruction: Who wrote the 2006 guidelines for the management of patients with valvular heart disease?

Output: ACC/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the 2006 guidelines for the management of patients with valvular heart disease?. ### Response: ACC/AHA.


Instruction: What is the name of the Task Force on Practice Guidelines?

Output: American HeartAssociation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Practice Guidelines?. ### Response: American HeartAssociation.


Instruction: What is CHAMP?

Output: Combination Hemotherapy and Mortality Prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CHAMP?. ### Response: Combination Hemotherapy and Mortality Prevention.


Instruction: What is the combination of warfarin and aspirin with aspirinalone?

Output: placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the combination of warfarin and aspirin with aspirinalone?. ### Response: placebo.


Instruction: What was the primary result of the CHAMP study?

Output: aspirinalone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary result of the CHAMP study?. ### Response: aspirinalone.


Instruction: What is the name of the trial that compared warfarin and aspirin with aspirinalone in survivors of acute myocardial infarction?

Output: CHAMP study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that compared warfarin and aspirin with aspirinalone in survivors of acute myocardial infarction?. ### Response: CHAMP study.


Instruction: How many patients were treated with oral anticoagulants in 2003?

Output: 62S–69S.99

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with oral anticoagulants in 2003?. ### Response: 62S–69S.99.


Instruction: What was compared to aspirin after heart valve replacement?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was compared to aspirin after heart valve replacement?. ### Response: warfarin.


Instruction: What is the name of the drug used to treat heart-valve replacement patients?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat heart-valve replacement patients?. ### Response: warfarin.


Instruction: When was the N Engl J Med 329:524-529?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 329:524-529?. ### Response: 1993.


Instruction: What is the difference between warfarin and dipyridamole-aspirin for the prevention of prosthetic heart valve thromboembolism?

Output: Warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between warfarin and dipyridamole-aspirin for the prevention of prosthetic heart valve thromboembolism?. ### Response: Warfarin.


Instruction: When was the Circulation.72:1059-1063?

Output: 1985

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.72:1059-1063?. ### Response: 1985.


Instruction: What was the outcome of the aprospective randomized clinical trial?

Output: Acomparison of three months of anticoagulation with extended anticoag-ulation for a first episode of idiopathic venous thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the aprospective randomized clinical trial?. ### Response: Acomparison of three months of anticoagulation with extended anticoag-ulation for a first episode of idiopathic venous thromboembolism.


Instruction: How long did anticoagulation take for a first episode of idiopathic venous thromboembolism?

Output: three months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did anticoagulation take for a first episode of idiopathic venous thromboembolism?. ### Response: three months.


Instruction: What is anticoagulation for a first episode of idiopathic venous thromboembolism?

Output: three months of anticoagulation with extended anticoag-ulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is anticoagulation for a first episode of idiopathic venous thromboembolism?. ### Response: three months of anticoagulation with extended anticoag-ulation.


Instruction: What is N EnglJ Med. 1999?

Output: 340:901–907.103

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is N EnglJ Med. 1999?. ### Response: 340:901–907.103.


Instruction: What are the AHA/ASA recommendations for the prevention of stroke inpatients with stroke and transient ischemic attack?

Output: Updateto

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the AHA/ASA recommendations for the prevention of stroke inpatients with stroke and transient ischemic attack?. ### Response: Updateto.


Instruction: What year did Stroke. 2008;39:1647–1652.104?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Stroke. 2008;39:1647–1652.104?. ### Response: 2008.


Instruction: What is the name of the person who was a part of the study?

Output: Fiore LD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who was a part of the study?. ### Response: Fiore LD.


Instruction: Who is a member of the research team?

Output: Fiore LD, Ezekowitz MD, Brophy MT, Lu D, Sacco J, Peduzzi P

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the research team?. ### Response: Fiore LD, Ezekowitz MD, Brophy MT, Lu D, Sacco J, Peduzzi P.


Instruction: What is one of the things that was cited as a contributing factor?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the things that was cited as a contributing factor?. ### Response: stroke.


Instruction: What did data pooled from trials of the impact of other therapies suggest?

Output: a worse outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did data pooled from trials of the impact of other therapies suggest?. ### Response: a worse outcome.


Instruction: What was also associated with use of anticonvulsants?

Output: vasospasm, DCI, and fever

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was also associated with use of anticonvulsants?. ### Response: vasospasm, DCI, and fever.


Instruction: What are antiepileptic drugs considered after aSAH?

Output: hydrocortisone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are antiepileptic drugs considered after aSAH?. ### Response: hydrocortisone.


Instruction: What were the studies small and hampered by?

Output: limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the studies small and hampered by?. ### Response: limitations.


Instruction: What is the immediate posthemorrhagic pe-riod (Class IIb; Level of Evidence B)?

Output: The use of prophylactic anticonvulsants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the immediate posthemorrhagic pe-riod (Class IIb; Level of Evidence B)?. ### Response: The use of prophylactic anticonvulsants.


Instruction: The routine long-term use of anticonvulsants is what?

Output: notrecommended

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The routine long-term use of anticonvulsants is what?. ### Response: notrecommended.


Instruction: What are known riskfactors for delayed seizure disorder?

Output: priorseizure, intracerebral hematoma, intractable hyper-tension, infarction, or aneurysm at the middle cere-bral artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are known riskfactors for delayed seizure disorder?. ### Response: priorseizure, intracerebral hematoma, intractable hyper-tension, infarction, or aneurysm at the middle cere-bral artery.


Instruction: Priorseizure, intracerebral hematoma, intractable hyper-tension, infarction, or aneurysm at the middle cere-bral arterial (Class IIb; Level of Evidence B)?

Output: priorseizure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Priorseizure, intracerebral hematoma, intractable hyper-tension, infarction, or aneurysm at the middle cere-bral arterial (Class IIb; Level of Evidence B)?. ### Response: priorseizure.


Instruction: What is frequently ob-served in the acute phase after aSAH?

Output: hypernatremia and hyponatremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is frequently ob-served in the acute phase after aSAH?. ### Response: hypernatremia and hyponatremia.


Instruction: Hyponatremia has been chronologically associated with what?

Output: the onset of sonographic and clinical vasospasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyponatremia has been chronologically associated with what?. ### Response: the onset of sonographic and clinical vasospasm.


Instruction: What can develop from different mechanisms afteraSAH?

Output: Hy-ponatremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can develop from different mechanisms afteraSAH?. ### Response: Hy-ponatremia.


Instruction: The syndrome cerebral salt wasting is produced by what type of secretion?

Output: excessive secretion of natriuretic peptides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The syndrome cerebral salt wasting is produced by what type of secretion?. ### Response: excessive secretion of natriuretic peptides.


Instruction: Hypo-natremia from excessive natriuresis may also provoke what?

Output: volume contraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypo-natremia from excessive natriuresis may also provoke what?. ### Response: volume contraction.


Instruction: The diagnosis of cerebral salt wastingis more common in patients with what grade?

Output: poor clinical grade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The diagnosis of cerebral salt wastingis more common in patients with what grade?. ### Response: poor clinical grade.


Instruction: What does using crystalloid orcolloid agents suggest can ameliorate the effect of cerebral salt wasting on the risk of cerebral ischemia after aSAH?

Output: aggressive volume resuscitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does using crystalloid orcolloid agents suggest can ameliorate the effect of cerebral salt wasting on the risk of cerebral ischemia after aSAH?. ### Response: aggressive volume resuscitation.


Instruction: What has one retrospective study suggested that 3% saline solution is effective incorrecting hyponatremia in this setting?

Output: 301,302

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has one retrospective study suggested that 3% saline solution is effective incorrecting hyponatremia in this setting?. ### Response: 301,302.


Instruction: What does hypertonic saline solution increase in patients with aSAH?

Output: regional cere-bral blood flow, brain tissue oxygen, and pH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does hypertonic saline solution increase in patients with aSAH?. ### Response: regional cere-bral blood flow, brain tissue oxygen, and pH.


Instruction: How many randomized, controlled trials have been performed to evaluate fludrocortisones to correct hyponatremia and fluidbalance?

Output: Two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized, controlled trials have been performed to evaluate fludrocortisones to correct hyponatremia and fluidbalance?. ### Response: Two.


Instruction: What did one trial find it helped to correct?

Output: negativesodium balance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did one trial find it helped to correct?. ### Response: negativesodium balance.


Instruction: What was the negativesodium balance?

Output: correct

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the negativesodium balance?. ### Response: correct.


Instruction: What did the other report a reduced need for?

Output: fluids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the other report a reduced need for?. ### Response: fluids.


Instruction: How was natriuresis reduced in the placebo controlled trials?

Output: howed reduced natriuresis and a lower rate of hyponatremiain aSAH patients treated with hydrocortisone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was natriuresis reduced in the placebo controlled trials?. ### Response: howed reduced natriuresis and a lower rate of hyponatremiain aSAH patients treated with hydrocortisone.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?

Output: March 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?. ### Response: March 2020.


Instruction: What did two SRs demonstrate that automated office blood pressure measurements were similar to?

Output: SBP and DBP obtained with day -time/awake ABPM and HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did two SRs demonstrate that automated office blood pressure measurements were similar to?. ### Response: SBP and DBP obtained with day -time/awake ABPM and HBPM.


Instruction: How many studies compared AOBP with daytime/awake ABPM and HBPM?

Output: 16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies compared AOBP with daytime/awake ABPM and HBPM?. ### Response: 16.


Instruction: What did Pappaccogli et al. show in their pooled analysis of 16 studies?

Output: no significant difference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Pappaccogli et al. show in their pooled analysis of 16 studies?. ### Response: no significant difference.


Instruction: How many studies did the same SR compare AOBP and HPBM?

Output: seven

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did the same SR compare AOBP and HPBM?. ### Response: seven.


Instruction: What did the SR find no statistically significant difference between the two methods?

Output: SBP and DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the SR find no statistically significant difference between the two methods?. ### Response: SBP and DBP.


Instruction: Who reported similar findings from 19 studies?

Output: Roerecke et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reported similar findings from 19 studies?. ### Response: Roerecke et al.


Instruction: What was the non-significant pooled mean difference in SBP between AOBP and awake ABPM in patients with an office SBP >130 mm Hg?

Output: 0.3 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the non-significant pooled mean difference in SBP between AOBP and awake ABPM in patients with an office SBP >130 mm Hg?. ### Response: 0.3 mm Hg.


Instruction: What did the Work Group not find?

Output: any evidence comparing the predictive value of AOBP versus out -of-office blood pressure on  clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group not find?. ### Response: any evidence comparing the predictive value of AOBP versus out -of-office blood pressure on  clinical outcomes.


Instruction: What did The Work Group not find any evidence comparing on clinical outcomes?

Output: predictive value of AOBP versus out -of-office blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did The Work Group not find any evidence comparing on clinical outcomes?. ### Response: predictive value of AOBP versus out -of-office blood pressure.


Instruction: What was another key reason for the recommendation to preferentially use ABPM and HBPM?

Output: the ability of out -of-office blood pressure to assist in the identification of white coat and masked HTN in untreated individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was another key reason for the recommendation to preferentially use ABPM and HBPM?. ### Response: the ability of out -of-office blood pressure to assist in the identification of white coat and masked HTN in untreated individuals.


Instruction: What did the 2014 VA/DoD HTN CPG help identify?

Output: white coat and masked HTN in untreated individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2014 VA/DoD HTN CPG help identify?. ### Response: white coat and masked HTN in untreated individuals.


Instruction: What was the 2015 USPSTF called?

Output: The 2014 VA/DoD HTN CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2015 USPSTF called?. ### Response: The 2014 VA/DoD HTN CPG.


Instruction: What did the 2014 VA/DoD HTN CPG, 2015 USPSTF, and 2017 AHA/ACC all recommend?

Output: ruling out white coat HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2014 VA/DoD HTN CPG, 2015 USPSTF, and 2017 AHA/ACC all recommend?. ### Response: ruling out white coat HTN.


Instruction: Why was white coat HTN ruled out in individuals with newly diagnosed elevated office blood pressure?

Output: to avoid unnecessary initiation of drug therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was white coat HTN ruled out in individuals with newly diagnosed elevated office blood pressure?. ### Response: to avoid unnecessary initiation of drug therapy.


Instruction: What type of medication was recommended to avoid unnecessary initiation of drug therapy?

Output: antihypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of medication was recommended to avoid unnecessary initiation of drug therapy?. ### Response: antihypertensive.


Instruction: What type of HTN is white coat HTN?

Output: masked

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of HTN is white coat HTN?. ### Response: masked.


Instruction: What is it possible that white coat TTN is not a totally benign condition?

Output: Since the evidence review and HTN outcome trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is it possible that white coat TTN is not a totally benign condition?. ### Response: Since the evidence review and HTN outcome trials.


Instruction: What is unknown whether patients with white coat HTN benefit or not benefit from treatment?

Output: it is unknown whether patients with white coat HTN benefit or do not benefit from treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unknown whether patients with white coat HTN benefit or not benefit from treatment?. ### Response: it is unknown whether patients with white coat HTN benefit or do not benefit from treatment.


Instruction: What did the Work Group conclude was low quality evidence supporting the utility of out -of-office blood pressure measurements?

Output: confirming diagnosis of HTN prior to the initiation of drug therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group conclude was low quality evidence supporting the utility of out -of-office blood pressure measurements?. ### Response: confirming diagnosis of HTN prior to the initiation of drug therapy.


Instruction: What are valuable methods in identifying masked HTN?

Output: ABPM and HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are valuable methods in identifying masked HTN?. ### Response: ABPM and HBPM.


Instruction: What is diagnosed with elevated out-of-office blood pressure in the setting of normal or controlled office blood pressure?

Output: masked HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is diagnosed with elevated out-of-office blood pressure in the setting of normal or controlled office blood pressure?. ### Response: masked HTN.


Instruction: What should be suspected in individuals with normal or controlled office blood pressure if they report higher home blood pressure values?

Output: Masked HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be suspected in individuals with normal or controlled office blood pressure if they report higher home blood pressure values?. ### Response: Masked HTN.


Instruction: What are some chronic conditions such as CKD?

Output: target organ da mage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some chronic conditions such as CKD?. ### Response: target organ da mage.


Instruction: We did not find any evidence of harm associated with what?

Output: ABPM and HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: We did not find any evidence of harm associated with what?. ### Response: ABPM and HBPM.


Instruction: What type of training is required for both ABPM and HBPM?

Output: patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of training is required for both ABPM and HBPM?. ### Response: patient.


Instruction: What could cause some differences in patient preferences?

Output: increased burden of out -of-office blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could cause some differences in patient preferences?. ### Response: increased burden of out -of-office blood pressure monitoring.


Instruction: What is a potential contri-butions of specialist care, clinical stability and optimalangiotensin-converting enzyme inhibitor dose atdischarge?

Output: Elimina-tion of early rehospitalization in a randomized,controlled trial of multidisciplinary care in a high-risk,elderly heart failure population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential contri-butions of specialist care, clinical stability and optimalangiotensin-converting enzyme inhibitor dose atdischarge?. ### Response: Elimina-tion of early rehospitalization in a randomized,controlled trial of multidisciplinary care in a high-risk,elderly heart failure population.


Instruction: What is the name of the randomized,controlled trial in a high-risk,elderly heart failure population?

Output: multidisciplinary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized,controlled trial in a high-risk,elderly heart failure population?. ### Response: multidisciplinary care.


Instruction: What is the name of the joint report of the American Association for Thoracic Surgery, the American College of Cardi-ology, and the Society for CardiovascularAngiography and Interventions?

Output: AATS/ACC/SCAI/STS expert consensus systems of caredocument: operator and institutional recommenda-tions and requirements for transcatheter mitral valveintervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the joint report of the American Association for Thoracic Surgery, the American College of Cardi-ology, and the Society for CardiovascularAngiography and Interventions?. ### Response: AATS/ACC/SCAI/STS expert consensus systems of caredocument: operator and institutional recommenda-tions and requirements for transcatheter mitral valveintervention.


Instruction: What does the College of Cardi-ology, Society for Cardiovascular Angiography and Interventions, and The Society of Thoracic Surgeons do?

Output: a joint report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the College of Cardi-ology, Society for Cardiovascular Angiography and Interventions, and The Society of Thoracic Surgeons do?. ### Response: a joint report.


Instruction: What does JACC VOL. 77, NO. 6, 20212021 Update to 2017?

Output: ECDP for Optimization of Heart Failure Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does JACC VOL. 77, NO. 6, 20212021 Update to 2017?. ### Response: ECDP for Optimization of Heart Failure Treatment.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 65 of 127 B. Conducting the Systematic Evidence Review Based on the decisions made by the Champions and Work Group members regarding the scope, KQs, and PICOTS statements?

Output: Conducting the Systematic Evidence Review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 65 of 127 B. Conducting the Systematic Evidence Review Based on the decisions made by the Champions and Work Group members regarding the scope, KQs, and PICOTS statements?. ### Response: Conducting the Systematic Evidence Review.


Instruction: What did the Lewin Team produce prior to conducting the review?

Output: systematic evidence review pr otocol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Lewin Team produce prior to conducting the review?. ### Response: systematic evidence review pr otocol.


Instruction: Who reviewed and approved the protocol?

Output: Champions and Work Group members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reviewed and approved the protocol?. ### Response: Champions and Work Group members.


Instruction: What was the final set of KQs?

Output: Systematic Evidence Review  Based on the decisions made by the Champions and Work Group members regarding the scope, the KQs, and the PICOTS statements, the Lewin Team produced a systematic evidence review pr otocol prior to conducting the review. The protocol was reviewed and approved by the Champions and Work Group members. It described in detail the final set of KQs, the methodology to be used during the systematic evidence review process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the final set of KQs?. ### Response: Systematic Evidence Review  Based on the decisions made by the Champions and Work Group members regarding the scope, the KQs, and the PICOTS statements, the Lewin Team produced a systematic evidence review pr otocol prior to conducting the review. The protocol was reviewed and approved by the Champions and Work Group members. It described in detail the final set of KQs, the methodology to be used during the systematic evidence review process.


Instruction: What is the final set of KQs?

Output: methodology to be used during the systematic evidence review process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the final set of KQs?. ### Response: methodology to be used during the systematic evidence review process.


Instruction: What are the inclusion/ exclusion criteria to be applied to each potential study?

Output: study type, sample size, and PICOTS criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the inclusion/ exclusion criteria to be applied to each potential study?. ### Response: study type, sample size, and PICOTS criteria.


Instruction: How many citations were identified potentially?

Output: 16,836

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many citations were identified potentially?. ### Response: 16,836.


Instruction: How many citations were identified potentially addressing the KQs of interest to this evidence review?

Output: 16,836

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many citations were identified potentially addressing the KQs of interest to this evidence review?. ### Response: 16,836.


Instruction: How many were excluded upon title review for clearly not meeting inclusion criteria?

Output: 4,831

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many were excluded upon title review for clearly not meeting inclusion criteria?. ### Response: 4,831.


Instruction: How many abstracts were reviewed?

Output: 12,005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many abstracts were reviewed?. ### Response: 12,005.


Instruction: How many were excluded from the review?

Output: 439

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many were excluded from the review?. ### Response: 439.


Instruction: What were the reasons for being excluded?

Output: not addressing a KQ of interest, not enrolling the population of interest, not meeting inclusion criteria for study design, not meeting inclusion criteria for any KQ, or being a duplicate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the reasons for being excluded?. ### Response: not addressing a KQ of interest, not enrolling the population of interest, not meeting inclusion criteria for study design, not meeting inclusion criteria for any KQ, or being a duplicate.


Instruction: What did not address a KQ of interest to this review?

Output: accepted study design

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not address a KQ of interest to this review?. ### Response: accepted study design.


Instruction: How many full length artic les were published?

Output: 863

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many full length artic les were published?. ### Response: 863.


Instruction: How many full length articles were reviewed?

Output: 863

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many full length articles were reviewed?. ### Response: 863.


Instruction: How many were excluded at a first pass review?

Output: 439

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many were excluded at a first pass review?. ### Response: 439.


Instruction: How many full-length articles were thought to address one or more KQs?

Output: 424

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many full-length articles were thought to address one or more KQs?. ### Response: 424.


Instruction: How many were ultimately excluded?

Output: 283

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many were ultimately excluded?. ### Response: 283.


Instruction: What are the reasons for their exclusion?

Output: not a systematic review or an accepted study design

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the reasons for their exclusion?. ### Response: not a systematic review or an accepted study design.


Instruction: How many studies addressed one or more of the KQs?

Output: 141

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies addressed one or more of the KQs?. ### Response: 141.


Instruction: What is the difference between aspirin and ticagrelor in acute stroke or transient ischemic attack?

Output: Ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between aspirin and ticagrelor in acute stroke or transient ischemic attack?. ### Response: Ticagrelor.


Instruction: When was the N Engl J Med 375:35–43 published?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 375:35–43 published?. ### Response: 2016.


Instruction: What is the name of the randomized clinical trial in which Ticagrelor is added to aspirin in prevention of dis-abling stroke?

Output: NAILED

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial in which Ticagrelor is added to aspirin in prevention of dis-abling stroke?. ### Response: NAILED.


Instruction: What is the name of the randomized clinical trial in prevention of dis-abling stroke?

Output: NAILED

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial in prevention of dis-abling stroke?. ### Response: NAILED.


Instruction: What does JAMA Neurol. 2020:78:1-9?

Output: Ticagrelor added to aspirin in acute ischemic stroke or transient ischemic attack in prevention of dis-abling stroke: a randomized clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does JAMA Neurol. 2020:78:1-9?. ### Response: Ticagrelor added to aspirin in acute ischemic stroke or transient ischemic attack in prevention of dis-abling stroke: a randomized clinical trial.


Instruction: Who is the COMPASS Investigator?

Output: Eikelboom JW, Connolly SJ, Bosch J, Dagenais GR, Hart RG, Shestakovska O, Diaz R, Alings M, Lonn EM, Anand SS, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the COMPASS Investigator?. ### Response: Eikelboom JW, Connolly SJ, Bosch J, Dagenais GR, Hart RG, Shestakovska O, Diaz R, Alings M, Lonn EM, Anand SS, et al.


Instruction: What does aspirin do in stable cardiovascular disease?

Output: Rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does aspirin do in stable cardiovascular disease?. ### Response: Rivaroxaban.


Instruction: What is the name of the N Engl J Med 2017377:1319-1330?

Output: Rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the N Engl J Med 2017377:1319-1330?. ### Response: Rivaroxaban.


Instruction: What was the initial result of the Integrated Care for the Reduction of Secondary Stroke model?

Output: Integrated care improves risk-factor modification after stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the initial result of the Integrated Care for the Reduction of Secondary Stroke model?. ### Response: Integrated care improves risk-factor modification after stroke.


Instruction: When was the J Neurol Neurosurg Psychiatry 80:279–284?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Neurol Neurosurg Psychiatry 80:279–284?. ### Response: 2009.


Instruction: What is ICARUSS an effective model for?

Output: risk factor man-agement in stroke survivors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ICARUSS an effective model for?. ### Response: risk factor man-agement in stroke survivors.


Instruction: What is a risk factor for stroke survivors?

Output: man-agement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for stroke survivors?. ### Response: man-agement.


Instruction: Int J Stroke. 2020;15:438–453. doi: 10.1177/1747493019830582 812. Nurse-led, telephone-based, secondary preventive follow-up after stroke or transient ischemic attack improves blood pressure and LDL cho-lesterol.

Output: 2009;80:279–284. doi: 10.1136/jnnp.2008.148122 811. Joubert J, Davis SM, Donnan GA, Levi C, Gonzales G, Joubert L, Hankey GJ. ICARUSS: An effective model for risk factor man-agement in stroke survivors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Stroke. 2020;15:438–453. doi: 10.1177/1747493019830582 812. Nurse-led, telephone-based, secondary preventive follow-up after stroke or transient ischemic attack improves blood pressure and LDL cho-lesterol.. ### Response: 2009;80:279–284. doi: 10.1136/jnnp.2008.148122 811. Joubert J, Davis SM, Donnan GA, Levi C, Gonzales G, Joubert L, Hankey GJ. ICARUSS: An effective model for risk factor man-agement in stroke survivors.


Instruction: How long did telephone-based follow-up after stroke and TIA improve risk factors?

Output: 36-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did telephone-based follow-up after stroke and TIA improve risk factors?. ### Response: 36-month.


Instruction: What was the first 12 months of the randomized, controlled NAILED stroke risk factor trial?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the first 12 months of the randomized, controlled NAILED stroke risk factor trial?. ### Response: 2015.


Instruction: How long did the NAILED stroke risk factor trial last?

Output: 36-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the NAILED stroke risk factor trial last?. ### Response: 36-month.


Instruction: What is the name of the randomized controlled trial that improved risk factors?

Output: NAILED

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial that improved risk factors?. ### Response: NAILED.


Instruction: When did the BMC Neurol publish the results?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the BMC Neurol publish the results?. ### Response: 2018.


Instruction: What is the name of the randomized controlled trial for blood pressure and lipid level control after minor stroke?

Output: PREVENTION

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial for blood pressure and lipid level control after minor stroke?. ### Response: PREVENTION.


Instruction: How many people were enrolled in the CMAJ 2014 study?

Output: 815

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the CMAJ 2014 study?. ### Response: 815.


Instruction: What type of care-based approach was used to evaluate the efficacy of a chronic care model?

Output: randomized con-trolled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care-based approach was used to evaluate the efficacy of a chronic care model?. ### Response: randomized con-trolled trial.


Instruction: What is the name of the randomized, con-trolled trial that evaluated the efficacy of a chronic care-based intervention on secondary stroke prevention among vulnerable stroke survivors?

Output: PREVENTION

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, con-trolled trial that evaluated the efficacy of a chronic care-based intervention on secondary stroke prevention among vulnerable stroke survivors?. ### Response: PREVENTION.


Instruction: What does Circ Cardiovasc Qual Outcomes.11:e003228 do?

Output: Efficacy of a chronic care-based intervention on secondary stroke prevention among vulnerable stroke survivors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Circ Cardiovasc Qual Outcomes.11:e003228 do?. ### Response: Efficacy of a chronic care-based intervention on secondary stroke prevention among vulnerable stroke survivors.


Instruction: How are stroke prevention clinic referrals associated with outpatient care?

Output: Organized outpatient care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are stroke prevention clinic referrals associated with outpatient care?. ### Response: Organized outpatient care.


Instruction: What is the 2018 ACHD Guideline?

Output: Stout et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 ACHD Guideline?. ### Response: Stout et al.


Instruction: When did the ACC and AHA translat scientific evidence into clinical practice guidelines with recommendations to improve cardio-vascular health?

Output: 1980

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the ACC and AHA translat scientific evidence into clinical practice guidelines with recommendations to improve cardio-vascular health?. ### Response: 1980.


Instruction: What are the guidelines based on?

Output: systematic methods to evaluate and classify evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the guidelines based on?. ### Response: systematic methods to evaluate and classify evidence.


Instruction: What do the guidelines provide a cornerstone for?

Output: quality cardiovascular care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the guidelines provide a cornerstone for?. ### Response: quality cardiovascular care.


Instruction: Who sponsor the development and pub-lication of guidelines?

Output: The ACC and AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who sponsor the development and pub-lication of guidelines?. ### Response: The ACC and AHA.


Instruction: What is the official policy of the ACC and AHA?

Output: Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the official policy of the ACC and AHA?. ### Response: Guidelines.


Instruction: What provide recommendations applica-ble to patients with or at risk of developing cardiovas-cular disease?

Output: Intended UsePractice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provide recommendations applica-ble to patients with or at risk of developing cardiovas-cular disease?. ### Response: Intended UsePractice guidelines.


Instruction: Where are guidelines developed?

Output: collabora-tion with other organizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are guidelines developed?. ### Response: collabora-tion with other organizations.


Instruction: What are guidelines intended to improve?

Output: pa-tients’ quality of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are guidelines intended to improve?. ### Response: pa-tients’ quality of care.


Instruction: What can have a global impact?

Output: guidelines developed in collabora-tion with other organizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can have a global impact?. ### Response: guidelines developed in collabora-tion with other organizations.


Instruction: What are guidelines intended to define?

Output: practices meeting the needs of patients in most, but not all, circumstances

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are guidelines intended to define?. ### Response: practices meeting the needs of patients in most, but not all, circumstances.


Instruction: What should not replace clinical judgment?

Output: Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not replace clinical judgment?. ### Response: Guidelines.


Instruction: How is Clinical ImplementationManagement effective?

Output: when followed by both practitioners  and patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is Clinical ImplementationManagement effective?. ### Response: when followed by both practitioners  and patients.


Instruction: What can be enhanced by shared decision-making between clinicians and patients?

Output: Adherence to recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be enhanced by shared decision-making between clinicians and patients?. ### Response: Adherence to recommendations.


Instruction: What can patient engagement in selecting in-terventions on the basis of individual values, preferences, and associated conditions and comorbidities?

Output: Adherence to recommendations can be enhanced by shared decision-making between clinicians and patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can patient engagement in selecting in-terventions on the basis of individual values, preferences, and associated conditions and comorbidities?. ### Response: Adherence to recommendations can be enhanced by shared decision-making between clinicians and patients.


Instruction: What is the name of the organization that continuously reviews, updates, and modifies guideline methodology?

Output: The ACC/AHA Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that continuously reviews, updates, and modifies guideline methodology?. ### Response: The ACC/AHA Task Force on Clinical Practice Guidelines.


Instruction: What does Task Force review, update, and modify on the basis of published standards from organizations?

Output: guideline methodology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Task Force review, update, and modify on the basis of published standards from organizations?. ### Response: guideline methodology.


Instruction: What are guidelines reevaluated and modified on the basis of?

Output: evolving tech-nologies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are guidelines reevaluated and modified on the basis of?. ### Response: evolving tech-nologies.


Instruction: To facilitate optimal dissemination of information to healthcare professionals at the point of care?

Output: guidelines may be used to inform regulatory or payer decisions, they are intended to improve pa-tients’ quality of care and align with patients’ interests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To facilitate optimal dissemination of information to healthcare professionals at the point of care?. ### Response: guidelines may be used to inform regulatory or payer decisions, they are intended to improve pa-tients’ quality of care and align with patients’ interests.


Instruction: What is the evolved format of presenting guideline recommendations and associated text called?

Output: mod-ular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the evolved format of presenting guideline recommendations and associated text called?. ### Response: mod-ular.


Instruction: What is the format for presenting guideline recommendations and associated text called?

Output: mod-ular knowledge chunk format

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the format for presenting guideline recommendations and associated text called?. ### Response: mod-ular knowledge chunk format.


Instruction: Each modular knowledge chunk format includes a table of related recommendations, a brief synopsis, what?

Output: recommendation-specific supportive text

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Each modular knowledge chunk format includes a table of related recommendations, a brief synopsis, what?. ### Response: recommendation-specific supportive text.


Instruction: References are provided at the end of the document in their respective sections?

Output: e698–e800

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: References are provided at the end of the document in their respective sections?. ### Response: e698–e800.


Instruction: What format will facilitate seamless updating of guidelines with fo-cused updates as new evidence is published?

Output: mod-ular knowledge chunk format

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What format will facilitate seamless updating of guidelines with fo-cused updates as new evidence is published?. ### Response: mod-ular knowledge chunk format.


Instruction: Which aspirin dose and preparation is best for the long-term prevention of cardiovascular disease and cancer?

Output: Lotrionte M, Biasucci LM, Peruzzi M, et al. Which aspirin dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which aspirin dose and preparation is best for the long-term prevention of cardiovascular disease and cancer?. ### Response: Lotrionte M, Biasucci LM, Peruzzi M, et al. Which aspirin dose.


Instruction: Preventive Services Task Force. 2016;164:826–35.

Output: S4.6-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preventive Services Task Force. 2016;164:826–35.. ### Response: S4.6-3.


Instruction: What is the name of the meta-analysis of aspirin in primary prevention of cardiovascular disease?

Output: Updated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of aspirin in primary prevention of cardiovascular disease?. ### Response: Updated.


Instruction: What are the names of the authors of the updated meta-analyse of Aspirin?

Output: Raju N, Sobieraj-Teague M, Bosch J, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the updated meta-analyse of Aspirin?. ### Response: Raju N, Sobieraj-Teague M, Bosch J, et al.


Instruction: How many patients with type 2 diabetes are treated with low-dose aspirine for primary prevention?

Output: S4.6-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with type 2 diabetes are treated with low-dose aspirine for primary prevention?. ### Response: S4.6-5.


Instruction: What is the primary prevention of atherosclerotic events in patients with type 2 diabetes?

Output: Low-dose aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention of atherosclerotic events in patients with type 2 diabetes?. ### Response: Low-dose aspirin.


Instruction: What is a factorial randomised placebo controlled trial?

Output: The prevention of progres-sion of arterial disease and diabetes (POPADAD) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a factorial randomised placebo controlled trial?. ### Response: The prevention of progres-sion of arterial disease and diabetes (POPADAD) trial.


Instruction: Aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease?

Output: POPADAD) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease?. ### Response: POPADAD) trial.


Instruction: BMJ. 2008;337:a1840. S4.6-7. Fowkes FGR, Price JF, Stewart MCW, et al. What is a randomized controlled trial of aspirin for prevention of cardiovascular events in a general population screened for?

Output: low ankle brachial index

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BMJ. 2008;337:a1840. S4.6-7. Fowkes FGR, Price JF, Stewart MCW, et al. What is a randomized controlled trial of aspirin for prevention of cardiovascular events in a general population screened for?. ### Response: low ankle brachial index.


Instruction: What is the ankle brachial index?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ankle brachial index?. ### Response: low.


Instruction: What is low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors?

Output: a randomized clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors?. ### Response: a randomized clinical trial.


Instruction: What is the effect of aspirin on cardio-vascular events and bleeding in the healthy elderly?

Output: McNeil JJ, Wolfe R, Woods RL, et al. Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of aspirin on cardio-vascular events and bleeding in the healthy elderly?. ### Response: McNeil JJ, Wolfe R, Woods RL, et al. Effect.


Instruction: What is a systematic review of?

Output: observa-tional studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of?. ### Response: observa-tional studies.


Instruction: Aspirin for primary cardiovascu-lar risk prevention and beyond in diabetes mellitus, Circulation. 2016;134:1579-94.

Output: Low-dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin for primary cardiovascu-lar risk prevention and beyond in diabetes mellitus, Circulation. 2016;134:1579-94.. ### Response: Low-dose.


Instruction: What is the acronym for the Antithrombotic Trialists’ Collaboration?

Output: ATT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Antithrombotic Trialists’ Collaboration?. ### Response: ATT.


Instruction: Aspirin in the primary and secondary prevention of vascular dis-ease: collaborative meta-analysis of individual participant data from randomised trials?

Output: Antithrombotic Trialists’ (ATT) Collaboration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin in the primary and secondary prevention of vascular dis-ease: collaborative meta-analysis of individual participant data from randomised trials?. ### Response: Antithrombotic Trialists’ (ATT) Collaboration.


Instruction: What is the name of the joint task force of the European Commission on cardiovascular disease prevention in clinical practice?

Output: The Sixth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the joint task force of the European Commission on cardiovascular disease prevention in clinical practice?. ### Response: The Sixth.


Instruction: Piepoli MF, Hoes AW, Agewall S, et al. 2016 European Guidelines on what?

Output: cardiovascular disease prevention in clinical practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Piepoli MF, Hoes AW, Agewall S, et al. 2016 European Guidelines on what?. ### Response: cardiovascular disease prevention in clinical practice.


Instruction: What is the Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice composed of?

Output: representatives of 10 societies and by invited experts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice composed of?. ### Response: representatives of 10 societies and by invited experts.


Instruction: How many societies are represented in the Joint Task force?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many societies are represented in the Joint Task force?. ### Response: 10.


Instruction: What is EACPR?

Output: European Association for Cardiovascular Prevention & Rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EACPR?. ### Response: European Association for Cardiovascular Prevention & Rehabilitation.


Instruction: Who contributed to the Special Contribution?

Output: European Association for Cardiovascular Prevention & Rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who contributed to the Special Contribution?. ### Response: European Association for Cardiovascular Prevention & Rehabilitation.


Instruction: What is the European Association for Cardiovascular Prevention & Rehabilitation?

Output: EACPR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the European Association for Cardiovascular Prevention & Rehabilitation?. ### Response: EACPR.


Instruction: What does EACPR stand for?

Output: European Association for Cardiovascular Prevention & Rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does EACPR stand for?. ### Response: European Association for Cardiovascular Prevention & Rehabilitation.


Instruction: When did Eur Heart J.37:2315-81 come out?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J.37:2315-81 come out?. ### Response: 2016.


Instruction: Who wrote AHA guidelines for primary care?

Output: Pearson TA, Blair SN, Daniels SR, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote AHA guidelines for primary care?. ### Response: Pearson TA, Blair SN, Daniels SR, et al.


Instruction: How many days after the index procedure were patients randomized to staged revascularization?

Output: 3 to 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days after the index procedure were patients randomized to staged revascularization?. ### Response: 3 to 40.


Instruction: How long did it take for patients to stage their PCI 1139STEMI?

Output: 3 to 40 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for patients to stage their PCI 1139STEMI?. ### Response: 3 to 40 days.


Instruction: What type of PCI was used?

Output: multivessel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of PCI was used?. ### Response: multivessel.


Instruction: How many months’ mean follow-up showed no between-group differences in the composite primary endpoint of all-cause death, nonfatal MI, and stroke?

Output: 38

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many months’ mean follow-up showed no between-group differences in the composite primary endpoint of all-cause death, nonfatal MI, and stroke?. ### Response: 38.


Instruction: The prior Class III (Harm) recommendation with regard to multivessel primary PCI in hemodynamically stable patients with STEMI has been upgraded to what?

Output: Class IIb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The prior Class III (Harm) recommendation with regard to multivessel primary PCI in hemodynamically stable patients with STEMI has been upgraded to what?. ### Response: Class IIb.


Instruction: What is a Class IIb recommendation for STEMI?

Output: multivessel PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Class IIb recommendation for STEMI?. ### Response: multivessel PCI.


Instruction: What should patients with STEMI consider at the time of primary PCI or as a planned, staged procedure?

Output: multivessel PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with STEMI consider at the time of primary PCI or as a planned, staged procedure?. ### Response: multivessel PCI.


Instruction: The writ-ing committee emphasizes that this change should not be interpreted as endorsing what?

Output: the routine performance of multives-sel PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The writ-ing committee emphasizes that this change should not be interpreted as endorsing what?. ### Response: the routine performance of multives-sel PCI.


Instruction: What should not be interpreted as endorsing the routine performance of multives-sel PCI in all patients with STEMI and multivessel disease?

Output: primary PCI in hemodynamically stable patients with STEMI has been upgraded and modified to a Class IIb recommendation to include consideration of multivessel PCI, either at the time of primary PCI or as a planned, staged procedure. The writ-ing committee emphasizes that this change

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be interpreted as endorsing the routine performance of multives-sel PCI in all patients with STEMI and multivessel disease?. ### Response: primary PCI in hemodynamically stable patients with STEMI has been upgraded and modified to a Class IIb recommendation to include consideration of multivessel PCI, either at the time of primary PCI or as a planned, staged procedure. The writ-ing committee emphasizes that this change.


Instruction: What should physicians integrate clinical data, lesion severity/complexity, and risk of contrast nephropathy to determine the optimal strategy?

Output: multivessel PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should physicians integrate clinical data, lesion severity/complexity, and risk of contrast nephropathy to determine the optimal strategy?. ### Response: multivessel PCI.


Instruction: What does contrast nephropathy determine?

Output: optimal strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does contrast nephropathy determine?. ### Response: optimal strategy.


Instruction: What is the strategy of routine PCI of noninfarct related arteries in hemodynamically stable patients?

Output: recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strategy of routine PCI of noninfarct related arteries in hemodynamically stable patients?. ### Response: recommendations.


Instruction: What type of PCI is associated with multivessel staged PCI?

Output: primary PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of PCI is associated with multivessel staged PCI?. ### Response: primary PCI.


Instruction: What is the term for patients who have spontaneous symptoms and myocardial ischemia?

Output: STEMI guideline with regard to PCI of a non–infarct-related artery at a time separate from primary PCI in patients who have spontaneous symptoms and myocardial ischemia or who have intermediate- or high-risk findings on noninva-sive testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for patients who have spontaneous symptoms and myocardial ischemia?. ### Response: STEMI guideline with regard to PCI of a non–infarct-related artery at a time separate from primary PCI in patients who have spontaneous symptoms and myocardial ischemia or who have intermediate- or high-risk findings on noninva-sive testing.


Instruction: What may be associated with better outcome than multivessel staged PCI?

Output: more patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with better outcome than multivessel staged PCI?. ### Response: more patients.


Instruction: What are there insufficient observational data and no randomized data at this time to inform a recommenda-tion regarding the optimal timing of?

Output: nonculprit vessel PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are there insufficient observational data and no randomized data at this time to inform a recommenda-tion regarding the optimal timing of?. ### Response: nonculprit vessel PCI.


Instruction: What is awaited to help clarify vessel PCI?

Output: Additional trial data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is awaited to help clarify vessel PCI?. ### Response: Additional trial data.


Instruction: What are issues related to the optimal method of evaluating nonculprit lesions?

Output: percent diameter stenosis, fractional flow reserve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are issues related to the optimal method of evaluating nonculprit lesions?. ### Response: percent diameter stenosis, fractional flow reserve.


Instruction: What did the 2011 PCI and 2013 STEMI guidelines recommend?

Output: aspiration thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2011 PCI and 2013 STEMI guidelines recommend?. ### Response: aspiration thrombectomy.


Instruction: What was the Class IIa recommendation for aspiration thrombectomy?

Output: before primary PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Class IIa recommendation for aspiration thrombectomy?. ### Response: before primary PCI.


Instruction: How many patients with STEMI were randomized to aspiration thrombectomy before or after primary PCI?

Output: 1071

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with STEMI were randomized to aspiration thrombectomy before or after primary PCI?. ### Response: 1071.


Instruction: How many multicenter trials were conducted in TAPAS?

Output: Three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many multicenter trials were conducted in TAPAS?. ### Response: Three.


Instruction: What was the name of the single-center study that randomized 1071 patients?

Output: TAPAS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the single-center study that randomized 1071 patients?. ### Response: TAPAS.


Instruction: How many multicenter trials enrolled signifi-cantly more patients than prior aspiration thrombectomy?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many multicenter trials enrolled signifi-cantly more patients than prior aspiration thrombectomy?. ### Response: 2.


Instruction: What is nephrotic-range proteinuria?

Output: stronglyassociated with poor blood pressure control in pediatric chronic kidneydisease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is nephrotic-range proteinuria?. ### Response: stronglyassociated with poor blood pressure control in pediatric chronic kidneydisease.


Instruction: What is the name of the group that analyzed children's blood pressure levels?

Output: Chronic Kidney Disease in Children Cohort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that analyzed children's blood pressure levels?. ### Response: Chronic Kidney Disease in Children Cohort.


Instruction: What is strongly associated with poor blood pressure control in pediatric chronic kidneydisease?

Output: Nephrotic-range proteinuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is strongly associated with poor blood pressure control in pediatric chronic kidneydisease?. ### Response: Nephrotic-range proteinuria.


Instruction: What is a report from the Chronic Kidney Disease inChildren study?

Output: Blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report from the Chronic Kidney Disease inChildren study?. ### Response: Blood pressure.


Instruction: What did the Chronic Kidney Disease inChildren study report?

Output: Blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Chronic Kidney Disease inChildren study report?. ### Response: Blood pressure.


Instruction: What was the name of the study?

Output: Chronic Kidney Disease inChildren

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: Chronic Kidney Disease inChildren.


Instruction: When was the study published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the study published?. ### Response: 2011.


Instruction: How many children had kidney disease?

Output: 369

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many children had kidney disease?. ### Response: 369.


Instruction: What type of hypertrophy is regressed in children and adolescents with hypertension duringramipril monotherapy?

Output: left-ventricular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypertrophy is regressed in children and adolescents with hypertension duringramipril monotherapy?. ### Response: left-ventricular.


Instruction: What year did Am J Hypertens publish a study on blood pressure in chronic kidney disease?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Am J Hypertens publish a study on blood pressure in chronic kidney disease?. ### Response: 2008.


Instruction: What is the acronym for Kidney Disease: Improving GlobalOutcomes?

Output: KDIGO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Kidney Disease: Improving GlobalOutcomes?. ### Response: KDIGO.


Instruction: Who is the IOM Committee on Standards for DevelopingTrustworthy Clinical Practice Guidelines?

Output: Institute of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the IOM Committee on Standards for DevelopingTrustworthy Clinical Practice Guidelines?. ### Response: Institute of Medicine.


Instruction: What is the name of the book published by National Academies Press in 2011?

Output: Clinical Practice Guidelines We Can Trust

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book published by National Academies Press in 2011?. ### Response: Clinical Practice Guidelines We Can Trust.


Instruction: What is AGREE II: advancing guidelinedevelopment, reporting?

Output: evaluation in health care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AGREE II: advancing guidelinedevelopment, reporting?. ### Response: evaluation in health care.


Instruction: What is AGREE II: advancing guidelinedevelopment, reporting and evaluation in health care?

Output: Standards for DevelopingTrustworthy Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AGREE II: advancing guidelinedevelopment, reporting and evaluation in health care?. ### Response: Standards for DevelopingTrustworthy Clinical Practice Guidelines.


Instruction: What is the J Clin Epidemiol.2010;63:1308-1311.378?

Output: velopment, reporting and evaluation in health care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Clin Epidemiol.2010;63:1308-1311.378?. ### Response: velopment, reporting and evaluation in health care.


Instruction: What year did Cochrane Database Syst Rev publish a review of exercise training for adults with chronic kidney disease?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Cochrane Database Syst Rev publish a review of exercise training for adults with chronic kidney disease?. ### Response: 2017.


Instruction: What is the name of the study published in 2020?

Output: Cochrane Database Syst Rev

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study published in 2020?. ### Response: Cochrane Database Syst Rev.


Instruction: Who wrote the review of Exercise Training for Adults with Chronic Kidney Disease?

Output: Heiwe S, Jacobson SH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the review of Exercise Training for Adults with Chronic Kidney Disease?. ### Response: Heiwe S, Jacobson SH.


Instruction: What is a potassium binder used for in people with chronic kidney disease?

Output: chronichyperkalaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potassium binder used for in people with chronic kidney disease?. ### Response: chronichyperkalaemia.


Instruction: What is the Cochrane Database of SystematicReviews 20141:CD010911?

Output: Antihypertensive agents for childrenwith chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Cochrane Database of SystematicReviews 20141:CD010911?. ### Response: Antihypertensive agents for childrenwith chronic kidney disease.


Instruction: What is a chronic kidney disease?

Output: Blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a chronic kidney disease?. ### Response: Blood pressure.


Instruction: What is the name of the Cochrane Database of SystematicReviews?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Cochrane Database of SystematicReviews?. ### Response: 2014.