Instruction: What is the name of the trial where patients were encouraged to go back to work?

Output: PAMI-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial where patients were encouraged to go back to work?. ### Response: PAMI-2.


Instruction: How long did the PAMI-2 trial last?

Output: 2weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the PAMI-2 trial last?. ### Response: 2weeks.


Instruction: What was the name of the RITA trial?

Output: Randomized InterventionTreatment of Angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the RITA trial?. ### Response: Randomized InterventionTreatment of Angina.


Instruction: What did revascularization with PCI lead to compared with CABG?

Output: earlier return to work

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did revascularization with PCI lead to compared with CABG?. ### Response: earlier return to work.


Instruction: What is the term for the metabolic equivalent of task?

Output: MET

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for the metabolic equivalent of task?. ### Response: MET.


Instruction: What type of exercise programs should be recommended to patients after PCI?

Output: Medically supervised

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of exercise programs should be recommended to patients after PCI?. ### Response: Medically supervised.


Instruction: What is supervised exercise training for?

Output: moderate- to high-riskpatients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is supervised exercise training for?. ### Response: moderate- to high-riskpatients.


Instruction: What is associated with sig-nificant reductions in all-cause mortality?

Output: Participation in cardiac rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with sig-nificant reductions in all-cause mortality?. ### Response: Participation in cardiac rehabilitation.


Instruction: What is the association between transcatheter aortic valve replacement and mor-tality or stroke?

Output: Makkar RR, Yoon S-H, Leon MB, et al. Association between transcatheter aortic valve replacement for bicuspid vs tricuspid aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between transcatheter aortic valve replacement and mor-tality or stroke?. ### Response: Makkar RR, Yoon S-H, Leon MB, et al. Association between transcatheter aortic valve replacement for bicuspid vs tricuspid aortic stenosis.


Instruction: What is Beckerman Z, Kayatta MO, McPherson L, et al.?

Output: Bicuspid aortic valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Beckerman Z, Kayatta MO, McPherson L, et al.?. ### Response: Bicuspid aortic valve repair.


Instruction: What is repair in the setting of severe aortic insufficiency?

Output: Bicuspid aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is repair in the setting of severe aortic insufficiency?. ### Response: Bicuspid aortic valve.


Instruction: What is J Vis Surg. 2018;4:101.6?

Output: Bicuspid aortic valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is J Vis Surg. 2018;4:101.6?. ### Response: Bicuspid aortic valve repair.


Instruction: How is left ventricular diastolic dys-function in patients with mitral stenosis undergoing percutaneous mitral balloon valvotomy?

Output: 337–44

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is left ventricular diastolic dys-function in patients with mitral stenosis undergoing percutaneous mitral balloon valvotomy?. ### Response: 337–44.


Instruction: What is Hyper tension in adult s: diagnosis and management (NG136)?

Output: NICE 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Hyper tension in adult s: diagnosis and management (NG136)?. ### Response: NICE 2023.


Instruction: When was the last updat ed?

Output: 18 Mar ch 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed?. ### Response: 18 Mar ch 2022.


Instruction: How many pages of 51 are on the Notice of right s?

Output: 38

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages of 51 are on the Notice of right s?. ### Response: 38.


Instruction: In-hospital and 1-year mortality in patients undergoing early surgery for prosthetic valve endocarditis.

Output: JAMA Intern Med. 2013;173:1495–504

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In-hospital and 1-year mortality in patients undergoing early surgery for prosthetic valve endocarditis.. ### Response: JAMA Intern Med. 2013;173:1495–504.


Instruction: What is the round table approach in?

Output: infective endocarditis & cardiovascular implantable electronic devices infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the round table approach in?. ### Response: infective endocarditis & cardiovascular implantable electronic devices infections.


Instruction: Infective endocarditis & cardiovascular implantable electronic devices infections: make your e-Team come true.

Output: The round table approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis & cardiovascular implantable electronic devices infections: make your e-Team come true.. ### Response: The round table approach.


Instruction: What is the impact of a multidisciplinary manage-ment strategy on the outcome of patients with native valve infective en-docarditis?

Output: Impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of a multidisciplinary manage-ment strategy on the outcome of patients with native valve infective en-docarditis?. ### Response: Impact.


Instruction: What is the outcome of patients with native valve infective en-docarditis?

Output: operative death and late mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the outcome of patients with native valve infective en-docarditis?. ### Response: operative death and late mortality.


Instruction: What is a management-based approach?

Output: Dramatic reduction in infective endocarditis-related mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a management-based approach?. ### Response: Dramatic reduction in infective endocarditis-related mortality.


Instruction: How did Botelho-Nevers E, Thuny F, Casalta JP, et al. manage infectives endocarditis-related mortality?

Output: management-based approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Botelho-Nevers E, Thuny F, Casalta JP, et al. manage infectives endocarditis-related mortality?. ### Response: management-based approach.


Instruction: What are the challenges and perspectives of management of infective endocarditis?

Output: Lancet. 2012;379:965–75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the challenges and perspectives of management of infective endocarditis?. ### Response: Lancet. 2012;379:965–75.


Instruction: What is a simplified risk scoring system?

Output: Outcomes for endocarditis surgery in North America

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simplified risk scoring system?. ### Response: Outcomes for endocarditis surgery in North America.


Instruction: Who is Sambola A?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Sambola A?. ### Response: 6.


Instruction: What is the name of the disease that affects native-valve infective endocarditis in a single tertiary care hospital?

Output: Sex differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects native-valve infective endocarditis in a single tertiary care hospital?. ### Response: Sex differences.


Instruction: In what year was the Am J Cardiol 106:92–8 published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Am J Cardiol 106:92–8 published?. ### Response: 2010.


Instruction: What was the JAMA's 2007297:1354–61?

Output: Contemporary clinical profile and outcome of prosthetic valve endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the JAMA's 2007297:1354–61?. ### Response: Contemporary clinical profile and outcome of prosthetic valve endocarditis.


Instruction: How long does it take for prosthetic valve endocarditis patients to die?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for prosthetic valve endocarditis patients to die?. ### Response: 1-year.


Instruction: What is the state of the heart?

Output: Prosthetic valve endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the state of the heart?. ### Response: Prosthetic valve endocarditis.


Instruction: How long is it advisable to have prosthetic heart surgery?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it advisable to have prosthetic heart surgery?. ### Response: 1-year.


Instruction: When did Nagpal A, Sohail MR, Steckelberg JM have surgery done?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Nagpal A, Sohail MR, Steckelberg JM have surgery done?. ### Response: 2013.


Instruction: What is valve endocarditis?

Output: prosthetic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is valve endocarditis?. ### Response: prosthetic.


Instruction: What is a determinant of operative death and late mortality?

Output: Active native valve endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a determinant of operative death and late mortality?. ### Response: Active native valve endocarditis.


Instruction: When did Jault F, Gandjbakhch I, Rama A, et al. publish?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Jault F, Gandjbakhch I, Rama A, et al. publish?. ### Response: 2012.


Instruction: What is complicated left-sided native valve endocarditis in adults?

Output: risk classification for mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is complicated left-sided native valve endocarditis in adults?. ### Response: risk classification for mortality.


Instruction: What is the risk classification for mortality?

Output: Complicated left-sided na-tive valve endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk classification for mortality?. ### Response: Complicated left-sided na-tive valve endocarditis.


Instruction: When did JAMA publish 289:1933-40?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA publish 289:1933-40?. ### Response: 2003.


Instruction: How did Kiefer T, Park L, Tribouilloy C, et al. assess the association between valvular surgery and mortality among patients?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Kiefer T, Park L, Tribouilloy C, et al. assess the association between valvular surgery and mortality among patients?. ### Response: heart failure.


Instruction: What year did the Cleveland Clinic experience early onset prosthetic valve endocarditis?

Output: 1992–1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Cleveland Clinic experience early onset prosthetic valve endocarditis?. ### Response: 1992–1997.


Instruction: What is the name of the disease that affects the late prosthetic valvule?

Output: infective en-docarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects the late prosthetic valvule?. ### Response: infective en-docarditis.


Instruction: When was the last time a patient was diagnosed with late prostheses?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a patient was diagnosed with late prostheses?. ### Response: 1992.


Instruction: How long was the prognosis of late prosthesis endo-carditus?

Output: Immediate and long-term

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the prognosis of late prosthesis endo-carditus?. ### Response: Immediate and long-term.


Instruction: What year did Ann Thorac Surg publish 69:1388–92?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Thorac Surg publish 69:1388–92?. ### Response: 2000.


Instruction: Who is responsible for surgery for infective endocarditis?

Output: Prendergast BD, Tornos P

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is responsible for surgery for infective endocarditis?. ### Response: Prendergast BD, Tornos P.


Instruction: When was Circulation published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation published?. ### Response: 2010.


Instruction: What is the impact of early surgery in the active phase on long-term outcomes?

Output: In-hospital and 1-year mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of early surgery in the active phase on long-term outcomes?. ### Response: In-hospital and 1-year mortality.


Instruction: What is left-sided native valve infective endocarditis?

Output: Complicated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is left-sided native valve infective endocarditis?. ### Response: Complicated.


Instruction: What year did J Thorac Cardiovasc Surg publish 142:836–42.e1?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Thorac Cardiovasc Surg publish 142:836–42.e1?. ### Response: 2011.


Instruction: What are the risks of dysglycemia and diabetes?

Output: the evidence is much more limited

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risks of dysglycemia and diabetes?. ### Response: the evidence is much more limited.


Instruction: What is the evidence in populations with CKD much more limited?

Output: risks of dysglycemia and diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the evidence in populations with CKD much more limited?. ### Response: risks of dysglycemia and diabetes.


Instruction: How many studies were conducted over 12 months showing that physical activity may improve SBP and DBP?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were conducted over 12 months showing that physical activity may improve SBP and DBP?. ### Response: 1.


Instruction: How long did the same study show that physical activity may improve eGFR?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the same study show that physical activity may improve eGFR?. ### Response: 12 months.


Instruction: What was inconsistent with other studies suggesting little or no differences?

Output: resistive and aerobic physical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was inconsistent with other studies suggesting little or no differences?. ### Response: resistive and aerobic physical activity.


Instruction: The Cochrane systematic review found that physicalactivity decreases weight and improves the mental components of quality of life in what disease?

Output: CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Cochrane systematic review found that physicalactivity decreases weight and improves the mental components of quality of life in what disease?. ### Response: CKD.


Instruction: How many patients were evaluated for CKD?

Output: 282

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were evaluated for CKD?. ### Response: 282.


Instruction: How many studies were evaluated?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were evaluated?. ### Response: 6.


Instruction: What did the systematic review find about the association of physical activity with increased study-reported adverse events?

Output: verylow-quality evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the systematic review find about the association of physical activity with increased study-reported adverse events?. ### Response: verylow-quality evidence.


Instruction: What did the available literature not allow differentiation between?

Output: resistive and aerobic physical activity, or betweensupervised and unsupervised physical activity programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the available literature not allow differentiation between?. ### Response: resistive and aerobic physical activity, or betweensupervised and unsupervised physical activity programs.


Instruction: What did observational data show?

Output: a dose –response relationship between greater levels of physicalactivity and lower risk of mortality in CKD patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did observational data show?. ### Response: a dose –response relationship between greater levels of physicalactivity and lower risk of mortality in CKD patients.


Instruction: What was the opinion of the Work Group that recommendations for the general population are likely to apply in CKD?

Output: Values and preferences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the opinion of the Work Group that recommendations for the general population are likely to apply in CKD?. ### Response: Values and preferences.


Instruction: What does the recommendation place a relative high value on?

Output: physical activity as a nonpharmacologicintervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the recommendation place a relative high value on?. ### Response: physical activity as a nonpharmacologicintervention.


Instruction: What is the high value on physical activity as a nonpharmacologicintervention?

Output: latively

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the high value on physical activity as a nonpharmacologicintervention?. ### Response: latively.


Instruction: What does the high prevalence of hypertension, diabetes, and CV disease in CKD populations suggest?

Output: the absolute bene ﬁt of physical activity may be especially highin people with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the high prevalence of hypertension, diabetes, and CV disease in CKD populations suggest?. ### Response: the absolute bene ﬁt of physical activity may be especially highin people with CKD.


Instruction: What may be especially high in people with CKD if the established relative bene fits in the general population are applicable toCKD?

Output: the absolute bene ﬁt of physical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be especially high in people with CKD if the established relative bene fits in the general population are applicable toCKD?. ### Response: the absolute bene ﬁt of physical activity.


Instruction: The higherpotential for bene fit is possibly offset by the high prevalence of what?

Output: comorbidity and frailty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The higherpotential for bene fit is possibly offset by the high prevalence of what?. ### Response: comorbidity and frailty.


Instruction: What might limit the level of physical activity CKD patients can achieve and increase the risk of adverse events?

Output: high prevalence ofcomorbidity and frailty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might limit the level of physical activity CKD patients can achieve and increase the risk of adverse events?. ### Response: high prevalence ofcomorbidity and frailty.


Instruction: The data on criticaloutcomes are not available and those for other healthbenefits are limited in what populations?

Output: CKD populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The data on criticaloutcomes are not available and those for other healthbenefits are limited in what populations?. ### Response: CKD populations.


Instruction: What is the result of a weakrecommendation in CKD populations?

Output: the data on criticaloutcomes are not available

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the result of a weakrecommendation in CKD populations?. ### Response: the data on criticaloutcomes are not available.


Instruction: What may some patients have limited ability to do due to severe cardiorespiratory ill-nesses?

Output: exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may some patients have limited ability to do due to severe cardiorespiratory ill-nesses?. ### Response: exercise.


Instruction: What group judged that most patients would benefit from efforts to perform physical activity regularly even if not achieving the goal?

Output: Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group judged that most patients would benefit from efforts to perform physical activity regularly even if not achieving the goal?. ### Response: Work Group.


Instruction: What type of haemorrhage should be followed if t hey have hydrocephalus?

Output: primar y intracer ebral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of haemorrhage should be followed if t hey have hydrocephalus?. ### Response: primar y intracer ebral.


Instruction: What should r eceiv e medical tr eatment initially be?

Output: management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should r eceiv e medical tr eatment initially be?. ### Response: management.


Instruction: What type of haemorrhage wit hout eit her h ydrocephalus or rapid neur ological deterioration?

Output: lobar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of haemorrhage wit hout eit her h ydrocephalus or rapid neur ological deterioration?. ### Response: lobar.


Instruction: What is a scor e on the Glasgo w Coma Scale of belo w 8?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scor e on the Glasgo w Coma Scale of belo w 8?. ### Response: 1.


Instruction: What should be formed within 48 hours of sympt om onset?

Output: hemicraniect omy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be formed within 48 hours of sympt om onset?. ### Response: hemicraniect omy.


Instruction: What criteria do people with acut e stroke meet?

Output: all of t he following crit eria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria do people with acut e stroke meet?. ### Response: all of t he following crit eria.


Instruction: What do clinical deficits that suggest inf arction in the territory of t he middle cer ebral artery suggest?

Output: additional inf arction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do clinical deficits that suggest inf arction in the territory of t he middle cer ebral artery suggest?. ### Response: additional inf arction.


Instruction: How many on t he NIHSS?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many on t he NIHSS?. ### Response: 15.


Instruction: How many signs on CT of an inf arct of at least 50% of the middle cer ebral?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many signs on CT of an inf arct of at least 50% of the middle cer ebral?. ### Response: •.


Instruction: At least what percentage of t he middle cer ebral ar tery territory?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At least what percentage of t he middle cer ebral ar tery territory?. ### Response: 50%.


Instruction: - with or without additional inf arction in t the territory of what side?

Output: same side

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: - with or without additional inf arction in t the territory of what side?. ### Response: same side.


Instruction: What is the infarct volume gr eater than 145 cm3?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the infarct volume gr eater than 145 cm3?. ### Response: －.


Instruction: What are the risks and benefits of decompr essiv e hemicraniect omy wit h people or heir f amily members or carers?

Output: 1.9.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risks and benefits of decompr essiv e hemicraniect omy wit h people or heir f amily members or carers?. ### Response: 1.9.6.


Instruction: What are t heir f amily members or car ers?

Output: Discuss t he risks and benefit s of decompr essiv e hemicraniect omy wit h people

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are t heir f amily members or car ers?. ### Response: Discuss t he risks and benefit s of decompr essiv e hemicraniect omy wit h people.


Instruction: What is taken int o account of their functional status?

Output: Discuss t he risks and benefit s of decompr essiv e hemicraniect omy wit h people or t heir f amily members or car ers (as appr opriat e), taking int o account t heir functional status bef ore the str oke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is taken int o account of their functional status?. ### Response: Discuss t he risks and benefit s of decompr essiv e hemicraniect omy wit h people or t heir f amily members or car ers (as appr opriat e), taking int o account t heir functional status bef ore the str oke.


Instruction: What is NICE 2023?

Output: diagnosis and initial management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2023?. ### Response: diagnosis and initial management.


Instruction: What is the last updat ed 13 April 2022?

Output: Page 21of 48

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 13 April 2022?. ### Response: Page 21of 48.


Instruction: What is routine transesophageal echocardiography for the evaluation of in elderly patients?

Output: cerebral emboli

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is routine transesophageal echocardiography for the evaluation of in elderly patients?. ### Response: cerebral emboli.


Instruction: What is the doi:10.1111/j.1540-8175.2005.00079.x540?

Output: Routine transesophageal echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi:10.1111/j.1540-8175.2005.00079.x540?. ### Response: Routine transesophageal echocardiography.


Instruction: What is clopidogrel better than?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel better than?. ### Response: aspirin.


Instruction: What is the effect of aspirin on platelet levels?

Output: Different antiplatelet strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of aspirin on platelet levels?. ### Response: Different antiplatelet strategies.


Instruction: How many strokes were there in 2016?

Output: 47:128–134

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 2016?. ### Response: 47:128–134.


Instruction: What is clopidogrel better than after strokes while on aspirin?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel better than after strokes while on aspirin?. ### Response: aspirin.


Instruction: What is the name of the retrospective cohort study?

Output: BMJ Open

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the retrospective cohort study?. ### Response: BMJ Open.


Instruction: When was a lipid-lowering therapy initiated?

Output: after coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a lipid-lowering therapy initiated?. ### Response: after coronary intervention.


Instruction: What is a predictor of long-term uti-lization?

Output: In-hospital initiation of lipid-low-ering therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of long-term uti-lization?. ### Response: In-hospital initiation of lipid-low-ering therapy.


Instruction: What year did Arch Intern Med issue 163:2576–2582?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Arch Intern Med issue 163:2576–2582?. ### Response: 2003.


Instruction: How many years ago did Cochrane Database Syst Rev issue 3:CD008286?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years ago did Cochrane Database Syst Rev issue 3:CD008286?. ### Response: 2016.


Instruction: What is an adjunct to pharmacotherapy for smoking cessation?

Output: behavioural support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an adjunct to pharmacotherapy for smoking cessation?. ### Response: behavioural support.


Instruction: What is another name for behavioural support?

Output: pharmacotherapy for smoking cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for behavioural support?. ### Response: pharmacotherapy for smoking cessation.


Instruction: When was this article published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 28, 2023.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive SummaryCirculation. 2019;140:e563–e595. DOI: 10.1161/CIR.0000000000000677 September 10, 2019 e579CLINICAL STATEMENTS AND GUIDELINES S2.1-25.

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive SummaryCirculation. 2019;140:e563–e595. DOI: 10.1161/CIR.0000000000000677 September 10, 2019 e579CLINICAL STATEMENTS AND GUIDELINES S2.1-25.. ### Response: Arnett et al.


Instruction: Pollitt RA, Rose KM, Kaufman JS. Evaluating the evidence for models of life course socioeconomic factors and cardiovascular outcomes: a systematic review.

Output: BMC Public Health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pollitt RA, Rose KM, Kaufman JS. Evaluating the evidence for models of life course socioeconomic factors and cardiovascular outcomes: a systematic review.. ### Response: BMC Public Health.


Instruction: What is the name of the systematic review of socioeconomic factors and cardiovascular outcomes?

Output: BMC Public Health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of socioeconomic factors and cardiovascular outcomes?. ### Response: BMC Public Health.


Instruction: When did BMC Public Health publish a systematic review?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did BMC Public Health publish a systematic review?. ### Response: 2005.


Instruction: What did DeFilippis AP, Young R, McEvoy JW, et al. study?

Output: Risk score overestimation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did DeFilippis AP, Young R, McEvoy JW, et al. study?. ### Response: Risk score overestimation.


Instruction: What is the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort?

Output: Risk score overestimation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort?. ### Response: Risk score overestimation.


Instruction: What is a scientific statement from the American heart association about health literacy and cardiovascular disease?

Output: fundamental relevance to primary and sec-ondary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scientific statement from the American heart association about health literacy and cardiovascular disease?. ### Response: fundamental relevance to primary and sec-ondary prevention.


Instruction: What is a scientific statement from the American Heart Association?

Output: Health literacy and cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scientific statement from the American Heart Association?. ### Response: Health literacy and cardiovascular disease.


Instruction: What is body size misperception a novel determinant in the obesity epidemic?

Output: Powell TM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is body size misperception a novel determinant in the obesity epidemic?. ### Response: Powell TM.


Instruction: What type of females have different shapes in different cultures?

Output: African-American and cau-casian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of females have different shapes in different cultures?. ### Response: African-American and cau-casian.


Instruction: What is the J Pediatr Adolesc Gynecol. 2003;16:349–54?

Output: S2.1-30

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Pediatr Adolesc Gynecol. 2003;16:349–54?. ### Response: S2.1-30.


Instruction: Where is the US Department of Health and Human Services. Healthy People 2020. Washington, DC: 2010.Availability: January 3, 2019.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the US Department of Health and Human Services. Healthy People 2020. Washington, DC: 2010.Availability: January 3, 2019.. ### Response: https://www.healthypeople.gov.


Instruction: What is a systematic review of built environment, selected risk factors and major cardiovascular disease outcomes?

Output: PLoS ONE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of built environment, selected risk factors and major cardiovascular disease outcomes?. ### Response: PLoS ONE.


Instruction: What is an umbrella for built and natural environment planning principles for promoting health?

Output: review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an umbrella for built and natural environment planning principles for promoting health?. ### Response: review.


Instruction: What are natural environment planning principles for promoting health?

Output: Built

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are natural environment planning principles for promoting health?. ### Response: Built.


Instruction: What is the BMC Public Health. 2018:930?

Output: an umbrella review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BMC Public Health. 2018:930?. ### Response: an umbrella review.


Instruction: Who is Kaiser P, Diez Roux AV, Mujahid M, et al. Neighborhood environ-ments and incident hypertension in the Multi-Ethnic Study of Atherosclerosis?

Output: Kaiser P

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Kaiser P, Diez Roux AV, Mujahid M, et al. Neighborhood environ-ments and incident hypertension in the Multi-Ethnic Study of Atherosclerosis?. ### Response: Kaiser P.


Instruction: What is an opportunity to pre-vent cardiometabolic disease?

Output: Addressing sleep disturbances

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an opportunity to pre-vent cardiometabolic disease?. ### Response: Addressing sleep disturbances.


Instruction: What is a sociodemographic and cultural determinant of sleep deficiency?

Output: implications for cardiometabolic disease risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a sociodemographic and cultural determinant of sleep deficiency?. ### Response: implications for cardiometabolic disease risk.


Instruction: What are sociodemographic and cultural determinants of sleep deficiency?

Output: implications for cardiometabolic disease risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are sociodemographic and cultural determinants of sleep deficiency?. ### Response: implications for cardiometabolic disease risk.


Instruction: What are implications for cardiometabolic disease risk?

Output: Sociodemographic and cultural determinants of sleep deficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implications for cardiometabolic disease risk?. ### Response: Sociodemographic and cultural determinants of sleep deficiency.


Instruction: Ismail K, Winkley K, Rabe-Hesketh S. Systematic review and meta-analysis of randomised controlled trials of psychological interventions to improve glycaemic control in patients with type 2 diabetes?

Output: Lancet. 2004;363:1589–97

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ismail K, Winkley K, Rabe-Hesketh S. Systematic review and meta-analysis of randomised controlled trials of psychological interventions to improve glycaemic control in patients with type 2 diabetes?. ### Response: Lancet. 2004;363:1589–97.


Instruction: In patients with type 2 diabetes, what is the name of the disease?

Output: cardiometabolic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with type 2 diabetes, what is the name of the disease?. ### Response: cardiometabolic.


Instruction: In 2004, what was the title of the Lancet's journal?

Output: 363:1589–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 2004, what was the title of the Lancet's journal?. ### Response: 363:1589–.


Instruction: What did Alam R, Sturt J, Lall R, and Lall do?

Output: An updated meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Alam R, Sturt J, Lall R, and Lall do?. ### Response: An updated meta-analysis.


Instruction: What is the difference between direct stenting and endoscopic atraumatic coronary artery bypass surgery in patients with proximal stenosis of the left descending artery?

Output: Primary directstenting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between direct stenting and endoscopic atraumatic coronary artery bypass surgery in patients with proximal stenosis of the left descending artery?. ### Response: Primary directstenting.


Instruction: What is the name of the prospective, randomised study of atraumatic coronary artery bypass surgery inpatients with proximal stenosis of the left anterior descending coronaryartery?

Output: Primary directstenting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective, randomised study of atraumatic coronary artery bypass surgery inpatients with proximal stenosis of the left anterior descending coronaryartery?. ### Response: Primary directstenting.


Instruction: What year did Kardiol Pol. 2004:61:253–61.180?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Kardiol Pol. 2004:61:253–61.180?. ### Response: 2004.


Instruction: How long did it take to follow-up after minimally invasive direct coronary arterial bypass grafting versus percu-taneous coronary intervention techniques?

Output: Midterm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to follow-up after minimally invasive direct coronary arterial bypass grafting versus percu-taneous coronary intervention techniques?. ### Response: Midterm.


Instruction: What is the name of the trial that compared bare metal stenting with internal mammaryartery grafting?

Output: SIMA (Stenting versus Internal Mammary Arterygrafting) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that compared bare metal stenting with internal mammaryartery grafting?. ### Response: SIMA (Stenting versus Internal Mammary Arterygrafting) trial.


Instruction: What is SIMA?

Output: Stenting versus Internal Mammary Arterygrafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SIMA?. ### Response: Stenting versus Internal Mammary Arterygrafting.


Instruction: When was the SIMA trial conducted?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the SIMA trial conducted?. ### Response: 2008.


Instruction: What is the name of the trial that compared minimally invasive internal thoracic artery bypass with percutaneous revascularisation forisolated lesions of the left anterior descending artery?

Output: SIMA (Stenting versus Internal Mammary Arterygrafting) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that compared minimally invasive internal thoracic artery bypass with percutaneous revascularisation forisolated lesions of the left anterior descending artery?. ### Response: SIMA (Stenting versus Internal Mammary Arterygrafting) trial.


Instruction: When was the J Am Coll Cardiol 52:815–7.182 published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 52:815–7.182 published?. ### Response: 2008.


Instruction: What is a meta-analysis of ran-domized arteries?

Output: Randomized comparison of percuta-neous coronary intervention with coronary artery bypass grafting indiabetic patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of ran-domized arteries?. ### Response: Randomized comparison of percuta-neous coronary intervention with coronary artery bypass grafting indiabetic patients.


Instruction: What is stenosis of the proximal left anterior descending artery?

Output: pass grafting versus percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stenosis of the proximal left anterior descending artery?. ### Response: pass grafting versus percutaneous coronary intervention.


Instruction: What is the name of the meta-analysis that compares minimally invasive direct coronary bypass grafting with percutaneous coronary intervention?

Output: A meta-analysis of ran-domized control trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis that compares minimally invasive direct coronary bypass grafting with percutaneous coronary intervention?. ### Response: A meta-analysis of ran-domized control trials.


Instruction: What is the difference between percutaneous coronary interventions and coronary artery bypass surgery?

Output: effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between percutaneous coronary interventions and coronary artery bypass surgery?. ### Response: effectiveness.


Instruction: When was the J Am Coll Cardiol Intv published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol Intv published?. ### Response: 2008.


Instruction: What was the impact of diabetes mellitus on the treatment of multivessel coronary disease patients?

Output: Clinical and economicimpact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the impact of diabetes mellitus on the treatment of multivessel coronary disease patients?. ### Response: Clinical and economicimpact.


Instruction: How long did the CARDia trial last?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the CARDia trial last?. ### Response: 1-year.


Instruction: What is the name of the ARTS trial?

Output: Arterial Revas-cularization Therapy Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ARTS trial?. ### Response: Arterial Revas-cularization Therapy Study.


Instruction: When was the Circulation.104:533-8.86?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.104:533-8.86?. ### Response: 2003.


Instruction: What is the acronym for Coronary Artery Re-vascularization in Diabetes?

Output: CARDia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Coronary Artery Re-vascularization in Diabetes?. ### Response: CARDia.


Instruction: What is a risk factor for development of cardiovascular disease?

Output: Kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for development of cardiovascular disease?. ### Response: Kidney disease.


Instruction: What are the Association Councils on Kidney in CardiovascularDisease, High Blood Pressure Research, Clinical Cardiology, and Epi-demology and Prevention?

Output: Kidney disease as a riskfactor for development of cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Association Councils on Kidney in CardiovascularDisease, High Blood Pressure Research, Clinical Cardiology, and Epi-demology and Prevention?. ### Response: Kidney disease as a riskfactor for development of cardiovascular disease.


Instruction: What is the Circulation. 2003;108:2154–69.188?

Output: American Heart Association Councils on Kidney in CardiovascularDisease, High Blood Pressure Research, Clinical Cardiology, and Epi-demiology and Prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Circulation. 2003;108:2154–69.188?. ### Response: American Heart Association Councils on Kidney in CardiovascularDisease, High Blood Pressure Research, Clinical Cardiology, and Epi-demiology and Prevention.


Instruction: Who is Roger VL, Go AS, Lloyd-Jones DM, et al on behalf of?

Output: AmericanHeart Association Statistics Committee and Stroke Statistics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Roger VL, Go AS, Lloyd-Jones DM, et al on behalf of?. ### Response: AmericanHeart Association Statistics Committee and Stroke Statistics.


Instruction: What year did the American Heart Association publish a report on stroke statistics?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the American Heart Association publish a report on stroke statistics?. ### Response: 2011.


Instruction: What is the name of the organization that released the 2011 update?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that released the 2011 update?. ### Response: American Heart Association.


Instruction: What is a therapeutic end point for the treatment of atrioventricular node reentrant tachycardia by catheter-guided radiofrequency current?

Output: slow pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a therapeutic end point for the treatment of atrioventricular node reentrant tachycardia by catheter-guided radiofrequency current?. ### Response: slow pathway.


Instruction: When did J Am Coll Cardiol. 1993;22:733–40?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 1993;22:733–40?. ### Response: 1993.


Instruction: What is the cause of supra-ventricular tachycardia?

Output: atrioventricular nodal reentry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of supra-ventricular tachycardia?. ### Response: atrioventricular nodal reentry.


Instruction: What is ablation of slow-pathway conduction used for?

Output: selective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ablation of slow-pathway conduction used for?. ### Response: selective.


Instruction: When did N Engl J Med issue 327:313–8?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 327:313–8?. ### Response: 1992.


Instruction: What are electrophysiologic characteristics and results of radiofrequency ablation?

Output: clinical features

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are electrophysiologic characteristics and results of radiofrequency ablation?. ### Response: clinical features.


Instruction: What are age at onset and gen-der of patients with different types of supraventricular tachycardias?

Output: Am J Cardiol. 1992;70:1213–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are age at onset and gen-der of patients with different types of supraventricular tachycardias?. ### Response: Am J Cardiol. 1992;70:1213–.


Instruction: What is a simple technique for selective radio-frequency ablation of the slow pathway in atrioventricular node reentrant tachycardia?

Output: catheter-guided radiofrequency current. J Am Coll Cardiol. 1993;22:733–40. 36. Jackman WM, Beckman KJ, McClelland JH, et al. Treatment of supra-ventricular tachycardia due to atrioventricular nodal reentry, by radio-frequency catheter ablation of slow-pathway conduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simple technique for selective radio-frequency ablation of the slow pathway in atrioventricular node reentrant tachycardia?. ### Response: catheter-guided radiofrequency current. J Am Coll Cardiol. 1993;22:733–40. 36. Jackman WM, Beckman KJ, McClelland JH, et al. Treatment of supra-ventricular tachycardia due to atrioventricular nodal reentry, by radio-frequency catheter ablation of slow-pathway conduction.


Instruction: What was the J Am Coll Cardiol. 1993;21:1612–21?

Output: A simple technique for selective radio-frequency ablation of the slow pathway in atrioventricular node reentrant tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol. 1993;21:1612–21?. ### Response: A simple technique for selective radio-frequency ablation of the slow pathway in atrioventricular node reentrant tachycardia.


Instruction: What is a symptomatic paroxysmal atrial fibrillation?

Output: Spontaneous occurrence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a symptomatic paroxysmal atrial fibrillation?. ### Response: Spontaneous occurrence.


Instruction: What is an untreated tachycardia?

Output: Spontaneous occurrence of symptomatic paroxysmal atrial fibrillation and paroxysmal supraventricu-lar tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an untreated tachycardia?. ### Response: Spontaneous occurrence of symptomatic paroxysmal atrial fibrillation and paroxysmal supraventricu-lar tachycardia.


Instruction: When did Wu D, Denes P, Amat-y-Leon F, et al. publish their findings?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Wu D, Denes P, Amat-y-Leon F, et al. publish their findings?. ### Response: April 23, 2023.


Instruction: What was rated as low quality?

Output: permanent study drug discontinuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as low quality?. ### Response: permanent study drug discontinuation.


Instruction: What was reported by the study as median and IQR?

Output: The evidence for change in peak VO2, 6 minute walk test distance and KCCQ clinical summary score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reported by the study as median and IQR?. ### Response: The evidence for change in peak VO2, 6 minute walk test distance and KCCQ clinical summary score.


Instruction: The comparison of IV iron with what was not assessed?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The comparison of IV iron with what was not assessed?. ### Response: imprecision.


Instruction: What did the comparison of IV iron with oral iron include?

Output: the same outcomes (mortality and change in NYHA class

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the comparison of IV iron with oral iron include?. ### Response: the same outcomes (mortality and change in NYHA class.


Instruction: What was rated as very low quality evidence?

Output: The comparison of IV iron with oral iron

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as very low quality evidence?. ### Response: The comparison of IV iron with oral iron.


Instruction: How has data on improvement in NYHA been extracted?

Output: where quality of life data is not reported in a trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How has data on improvement in NYHA been extracted?. ### Response: where quality of life data is not reported in a trial.


Instruction: What did NYHA extract where quality of life data is not reported in a trial?

Output: data on improvement in NYHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did NYHA extract where quality of life data is not reported in a trial?. ### Response: data on improvement in NYHA.


Instruction: What showed a clinical harm of IV iron when compared to oral iron?

Output: Change in NYHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What showed a clinical harm of IV iron when compared to oral iron?. ### Response: Change in NYHA.


Instruction: What did not show a clear eff ect?

Output: Mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not show a clear eff ect?. ### Response: Mortality.


Instruction: What was the confidence interval ranging from a decrease and increase in all-cause mortality?

Output: Mortality did not demonstrate a clear eff ect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the confidence interval ranging from a decrease and increase in all-cause mortality?. ### Response: Mortality did not demonstrate a clear eff ect.


Instruction: One cost -utility analysis found that iron supplementation was cost effective compared to what?

Output: no iron treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: One cost -utility analysis found that iron supplementation was cost effective compared to what?. ### Response: no iron treatment.


Instruction: What is the cost of iron treatment for patients with heart failure and iron deficiency?

Output: £3,997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost of iron treatment for patients with heart failure and iron deficiency?. ### Response: £3,997.


Instruction: What was the cost per QALY of ICER?

Output: £3,997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the cost per QALY of ICER?. ### Response: £3,997.


Instruction: What is NICE 2018?

Output: All rights reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: All rights reserved.


Instruction: What is the difference between home-based MDT clinics and usual care in high risk patients?

Output: 1. Usual care  2. MDT  - consisting of a heart failure nurse, palliative care nurse, cardiologist, palliative care physician, physiotherapist and occupational therapist   6 month follow -up 2-1: Cost saving of £1,517  2-1: 0.03 QALYs  2 dominates 1 (more effective and less costl y)  Uncertainty not reported for cost effectiveness   Conclusions robust to sensitivity analyses.   Abbreviations: QALY: quality -adjusted life years; RCT: randomised controlled trial  (a) Single centre study from a county council hospital in Vӓsterbotten County, Sweden and therefore resource use and 2012 costs may not reflect current UK NHS context

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between home-based MDT clinics and usual care in high risk patients?. ### Response: 1. Usual care  2. MDT  - consisting of a heart failure nurse, palliative care nurse, cardiologist, palliative care physician, physiotherapist and occupational therapist   6 month follow -up 2-1: Cost saving of £1,517  2-1: 0.03 QALYs  2 dominates 1 (more effective and less costl y)  Uncertainty not reported for cost effectiveness   Conclusions robust to sensitivity analyses.   Abbreviations: QALY: quality -adjusted life years; RCT: randomised controlled trial  (a) Single centre study from a county council hospital in Vӓsterbotten County, Sweden and therefore resource use and 2012 costs may not reflect current UK NHS context.


Instruction: What is the difference between intervention and usual care in high risk patients?

Output: 1. Usual care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between intervention and usual care in high risk patients?. ### Response: 1. Usual care.


Instruction: What are the limitations of study applicability?

Output: Potentially serious limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the limitations of study applicability?. ### Response: Potentially serious limitations.


Instruction: What is a health outcome of an RCT study?

Output: QALYs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a health outcome of an RCT study?. ### Response: QALYs.


Instruction: What is the population of adults with chronic heart failure with NYHA class III -IV symptoms and a marker of severity?

Output: Population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population of adults with chronic heart failure with NYHA class III -IV symptoms and a marker of severity?. ### Response: Population.


Instruction: What type of care includes a heart failure nurse, palliative care nurse, cardiologist, physiotherapist and occupational therapist?

Output: MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care includes a heart failure nurse, palliative care nurse, cardiologist, physiotherapist and occupational therapist?. ### Response: MDT.


Instruction: What is the cost saving of a 2-1: 0.03 QALYs 2 dominates 1?

Output: £1,517

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost saving of a 2-1: 0.03 QALYs 2 dominates 1?. ### Response: £1,517.


Instruction: How many QALYs dominates 1?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many QALYs dominates 1?. ### Response: 2.


Instruction: Uncertainty not reported for what?

Output: cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Uncertainty not reported for what?. ### Response: cost effectiveness.


Instruction: RCT: Randomised controlled trial.

Output: Single centre study from a county council hospital in Vӓsterbotten County, Sweden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: RCT: Randomised controlled trial.. ### Response: Single centre study from a county council hospital in Vӓsterbotten County, Sweden.


Instruction: What may not reflect current UK NHS context?

Output: resource use and 2012 costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not reflect current UK NHS context?. ### Response: resource use and 2012 costs.


Instruction: What might not capture full costs and effects of the intervention?

Output: Short time horizon

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might not capture full costs and effects of the intervention?. ### Response: Short time horizon.


Instruction: EQ -5D reported differently to what?

Output: the clinical trial evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: EQ -5D reported differently to what?. ### Response: the clinical trial evidence.


Instruction: What was carried out to quantify uncertainty?

Output: minimal sensitivity anal yses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was carried out to quantify uncertainty?. ### Response: minimal sensitivity anal yses.


Instruction: MDT clinic vs usual care in high risk patients

Output: 1. Usual care  2. MDT  - consisting of a heart failure nurse, palliative care nurse, cardiologist, palliative care physician, physiotherapist and occupational therapist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: MDT clinic vs usual care in high risk patients. ### Response: 1. Usual care  2. MDT  - consisting of a heart failure nurse, palliative care nurse, cardiologist, palliative care physician, physiotherapist and occupational therapist.


Instruction: What is the study applicability limitation?

Output: Potentially serious limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the study applicability limitation?. ### Response: Potentially serious limitations.


Instruction: What are the study effects?

Output: Incremental effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the study effects?. ### Response: Incremental effects.


Instruction: Where is Atienza from?

Output: Spain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Atienza from?. ### Response: Spain.


Instruction: What is the mortality rate for 1 year?

Output: 1 year mortality rate, all -cause 2-1: cost saving of £1,719

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mortality rate for 1 year?. ### Response: 1 year mortality rate, all -cause 2-1: cost saving of £1,719.


Instruction: How much money is saved by using the same paper?

Output: £1,517

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much money is saved by using the same paper?. ### Response: £1,517.


Instruction: How long does pravastatin therapy last in diabetic patients undergoing complete coronary revascularization?

Output: Long-term efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does pravastatin therapy last in diabetic patients undergoing complete coronary revascularization?. ### Response: Long-term efficacy.


Instruction: What is the name of the drug that is used to treat diabetics undergoing a total coronary intervention?

Output: pravastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat diabetics undergoing a total coronary intervention?. ### Response: pravastatin.


Instruction: When did the J Atheroscler Thromb publish its findings?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Atheroscler Thromb publish its findings?. ### Response: 2010.


Instruction: What decreases adverse out-comes in coronary artery bypass?

Output: Statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What decreases adverse out-comes in coronary artery bypass?. ### Response: Statins.


Instruction: What does Statins decrease?

Output: adverse out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Statins decrease?. ### Response: adverse out-comes.


Instruction: When did Cardiovasc Ther. 2010;28:70–79. doi:10.1111/j.1755-5922.2009.00098.x?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Cardiovasc Ther. 2010;28:70–79. doi:10.1111/j.1755-5922.2009.00098.x?. ### Response: 2010.


Instruction: What treatment equalizes long-term survival between patients with single and bilateral internal tho-racic artery grafts?

Output: Statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What treatment equalizes long-term survival between patients with single and bilateral internal tho-racic artery grafts?. ### Response: Statin.


Instruction: Why do patients choose PCI over CABG?

Output: it is less invasiveand provides for quicker recovery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do patients choose PCI over CABG?. ### Response: it is less invasiveand provides for quicker recovery.


Instruction: What is more frequently performed after PCI?

Output: repeatrevascularization procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more frequently performed after PCI?. ### Response: repeatrevascularization procedures.


Instruction: Patients' preferences are often influenced by what?

Output: their attitudes toward risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients' preferences are often influenced by what?. ### Response: their attitudes toward risk.


Instruction: What is the term for attitudes toward risk and the tendency to let immediate smaller benefits outweigh larger future risks?

Output: temporal discounting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for attitudes toward risk and the tendency to let immediate smaller benefits outweigh larger future risks?. ### Response: temporal discounting.


Instruction: What is a phenomenon called?

Output: temporal discounting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a phenomenon called?. ### Response: temporal discounting.


Instruction: Who should receive a thoroughhistory of their chest pain?

Output: Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should receive a thoroughhistory of their chest pain?. ### Response: Patients.


Instruction: What should patients with chest pain receive to assess the prob-ability of IHD before additional testing?

Output: a thoroughhistory and physical examination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with chest pain receive to assess the prob-ability of IHD before additional testing?. ### Response: a thoroughhistory and physical examination.


Instruction: Patients who present with acute angina should be classified as stable or unstable; patients with UAshould be further categorized as being at high,moderate, or low risk?

Output: 52

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients who present with acute angina should be classified as stable or unstable; patients with UAshould be further categorized as being at high,moderate, or low risk?. ### Response: 52.


Instruction: What is the key first step in evaluating apatient with chest pain?

Output: The clinical examination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the key first step in evaluating apatient with chest pain?. ### Response: The clinical examination.


Instruction: What should include a detailed assess-ment of symptoms?

Output: clinical examination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should include a detailed assess-ment of symptoms?. ### Response: clinical examination.


Instruction: What are some adjectives used to describe anginal pain?

Output: squeezing,” “grip-like,” “suf-focating,” and “heavy,”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some adjectives used to describe anginal pain?. ### Response: squeezing,” “grip-like,” “suf-focating,” and “heavy,”.


Instruction: What type of pain is rarely sharp or stabbing?

Output: anginal pain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of pain is rarely sharp or stabbing?. ### Response: anginal pain.


Instruction: How might a patient demonstrate the classic Levine'ssign?

Output: by placing a clenched fist over the precordium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How might a patient demonstrate the classic Levine'ssign?. ### Response: by placing a clenched fist over the precordium.


Instruction: What might be demonstrated by placing a clenched fist over the precordium to describe the pain?

Output: Levine’ssign

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be demonstrated by placing a clenched fist over the precordium to describe the pain?. ### Response: Levine’ssign.


Instruction: Many patients do not describe angina as frank pain but as tightness, pressure, or what else?

Output: discomfort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Many patients do not describe angina as frank pain but as tightness, pressure, or what else?. ### Response: discomfort.


Instruction: What is the class of recommendations in the ACCF/AHA Table 1?

Output: Class I1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of recommendations in the ACCF/AHA Table 1?. ### Response: Class I1.


Instruction: The algorithms do not represent a comprehensive list of what?

Output: recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The algorithms do not represent a comprehensive list of what?. ### Response: recommendations.


Instruction: What is relatively contraindicated when triglycerides are /H11350200 mg/dL?

Output: bile acid sequestrant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is relatively contraindicated when triglycerides are /H11350200 mg/dL?. ### Response: bile acid sequestrant.


Instruction: What does ACCF stand for?

Output: American College of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACCF stand for?. ### Response: American College of Cardiology Foundation.


Instruction: What is the acronym for angiotensin-converting enzyme inhibitor?

Output: ACEI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for angiotensin-converting enzyme inhibitor?. ### Response: ACEI.


Instruction: ARB stands for what?

Output: angiotensin-receptor blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ARB stands for what?. ### Response: angiotensin-receptor blocker.


Instruction: ATP III stands for adult treatment panel 3.

Output: ATP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ATP III stands for adult treatment panel 3.. ### Response: ATP.


Instruction: What is III, Adult Treatment Panel 3?

Output: ATP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is III, Adult Treatment Panel 3?. ### Response: ATP.


Instruction: What is BP, blood pressure; CCB, calcium channel blocker; CKD,chronic kidney disease?

Output: calcium channel blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is BP, blood pressure; CCB, calcium channel blocker; CKD,chronic kidney disease?. ### Response: calcium channel blocker.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227.


Instruction: What are bicuspid aortic valves associ-ated with out of proportion to coexistent valvular lesions?

Output: aortic dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are bicuspid aortic valves associ-ated with out of proportion to coexistent valvular lesions?. ### Response: aortic dilatation.


Instruction: What causes dilatation out of proportion to coexistent valvular lesions?

Output: Bicuspid aortic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes dilatation out of proportion to coexistent valvular lesions?. ### Response: Bicuspid aortic valves.


Instruction: What is the bicuspid aortic valve: an integrated phenotypic classification of leaflet morphology?

Output: aortic root shape

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the bicuspid aortic valve: an integrated phenotypic classification of leaflet morphology?. ### Response: aortic root shape.


Instruction: What is endorsed by the Society of Cardiovascular Computed Tomography and Society for Car-diovascular Magnetic Resonance?

Output: Multimodality imaging of diseases of the thoracic aorta in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is endorsed by the Society of Cardiovascular Computed Tomography and Society for Car-diovascular Magnetic Resonance?. ### Response: Multimodality imaging of diseases of the thoracic aorta in adults.


Instruction: What year did J Am Soc Echocardiogr. 2015;28:119–82?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Am Soc Echocardiogr. 2015;28:119–82?. ### Response: 2015.


Instruction: What type of magnetic resonance is associated with valvular dysfunction and bicuspid aor -topathy?

Output: Magnetic Resonance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of magnetic resonance is associated with valvular dysfunction and bicuspid aor -topathy?. ### Response: Magnetic Resonance.


Instruction: What is the JACC Cardiovasc Imaging's 2013 report?

Output: 6:150–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JACC Cardiovasc Imaging's 2013 report?. ### Response: 6:150–.


Instruction: What type of aneurysm is found in patients with functionally normal or minimally stenotic bicuspid aortic valve?

Output: Aortic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of aneurysm is found in patients with functionally normal or minimally stenotic bicuspid aortic valve?. ### Response: Aortic.


Instruction: What is the cause of left ven-tricular outflow tract obstruction?

Output: coexistent valvular lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of left ven-tricular outflow tract obstruction?. ### Response: coexistent valvular lesions.


Instruction: Who should cardiac screening be offered to?

Output: first-degree relatives

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should cardiac screening be offered to?. ### Response: first-degree relatives.


Instruction: What is the difference between a functionally normal and minimally stenotic bicuspid aortic valve?

Output: Aortic aneurysm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between a functionally normal and minimally stenotic bicuspid aortic valve?. ### Response: Aortic aneurysm.


Instruction: When did the Am J Car -diol. 1991 issue 67:781–2?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Am J Car -diol. 1991 issue 67:781–2?. ### Response: 1991.


Instruction: What did Hahn RT, Roman MJ, Mogtader AH, et al. associate with?

Output: aortic dilation with regurgitant, stenotic and functionally normal bicuspid aortic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Hahn RT, Roman MJ, Mogtader AH, et al. associate with?. ### Response: aortic dilation with regurgitant, stenotic and functionally normal bicuspid aortic valves.


Instruction: In what year did the J Am Coll Cardiol. 1992 issue 19:283-8?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the J Am Coll Cardiol. 1992 issue 19:283-8?. ### Response: 2003.


Instruction: What is the name of the disease in young men with normally functioning bicuspid aortic valves?

Output: Aortic aneurysm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease in young men with normally functioning bicuspid aortic valves?. ### Response: Aortic aneurysm.


Instruction: What is Novaro GM, Tiong IY, Pearce GL, et al. associated with?

Output: a congenital bicuspid aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Novaro GM, Tiong IY, Pearce GL, et al. associated with?. ### Response: a congenital bicuspid aortic valve.


Instruction: What is a congenital bicuspid aortic valve associated with?

Output: aortic dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a congenital bicuspid aortic valve associated with?. ### Response: aortic dilatation.


Instruction: What is the name of the consortium that identifies knowledge gaps and rises to the challenge from the International Bicuspid Aortic Valve Consortium?

Output: BAVCon

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the consortium that identifies knowledge gaps and rises to the challenge from the International Bicuspid Aortic Valve Consortium?. ### Response: BAVCon.


Instruction: What is the name of the systematic review of contemporary natural history of bi-cuspid aortic valve disease?

Output: Heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of contemporary natural history of bi-cuspid aortic valve disease?. ### Response: Heart.


Instruction: What is Ferencik M, Pape LA?

Output: Changes in size of ascending aorta and aortic valve function with time in patients with congenitally bicuspid aortic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Ferencik M, Pape LA?. ### Response: Changes in size of ascending aorta and aortic valve function with time in patients with congenitally bicuspid aortic valves.


Instruction: How does aortic valve function with time in patients with congenitally bicuspid valves?

Output: Changes in size of ascending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does aortic valve function with time in patients with congenitally bicuspid valves?. ### Response: Changes in size of ascending aorta.


Instruction: When did Michelena HI, Khanna AD, Mahoney D, et al. incidence of aartic complica-tions in patients?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Michelena HI, Khanna AD, Mahoney D, et al. incidence of aartic complica-tions in patients?. ### Response: 2011.


Instruction: How did Davies RR, Goldstein LJ, Coady MA, and others evaluate yearly rupture or not?

Output: dissection rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Davies RR, Goldstein LJ, Coady MA, and others evaluate yearly rupture or not?. ### Response: dissection rates.


Instruction: What are the yearly rupture or dissection rates?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the yearly rupture or dissection rates?. ### Response: 4.


Instruction: Who provided support?

Output: ERT)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who provided support?. ### Response: ERT).


Instruction: How are the methods used by the ERT described?

Output: Methods for Guideline Developmentsection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the methods used by the ERT described?. ### Response: Methods for Guideline Developmentsection.


Instruction: What are the research recommendations described to inform?

Output: ongoing research agendas in the international community

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the research recommendations described to inform?. ### Response: ongoing research agendas in the international community.


Instruction: What does GRADE stand for?

Output: Recommendations Assessment, Development and Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GRADE stand for?. ### Response: Recommendations Assessment, Development and Evaluation.


Instruction: What do the recommendations and statements created in this guideline serve to direct?

Output: both care and research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the recommendations and statements created in this guideline serve to direct?. ### Response: both care and research.


Instruction: What is not intended to serve as a textbook ofmedicine or nephrology?

Output: Grading ofRecommendations Assessment, Development and Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not intended to serve as a textbook ofmedicine or nephrology?. ### Response: Grading ofRecommendations Assessment, Development and Evaluation.


Instruction: What are still valid with respect to theKDOQI 2003 guidelines?

Output: drug dosing and interaction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are still valid with respect to theKDOQI 2003 guidelines?. ### Response: drug dosing and interaction.


Instruction: How many large RCTs and post hocanalyses of patients with CKD from statin trials of the generalpopulation?

Output: few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many large RCTs and post hocanalyses of patients with CKD from statin trials of the generalpopulation?. ### Response: few.


Instruction: The guideline proposes a new concept in themanagement of dyslipidemia in what condition?

Output: CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The guideline proposes a new concept in themanagement of dyslipidemia in what condition?. ### Response: CKD.


Instruction: What is the requirement for a guideline in the hope of stimulating discussion and generating substantial research?

Output: dyslipidemia in CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the requirement for a guideline in the hope of stimulating discussion and generating substantial research?. ### Response: dyslipidemia in CKD.


Instruction: How long will the need for an update be assessed?

Output: in ﬁveyears

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long will the need for an update be assessed?. ### Response: in ﬁveyears.


Instruction: What may lead to changes to the recommendations?

Output: important newevidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may lead to changes to the recommendations?. ### Response: important newevidence.


Instruction: What may recommendationsor modify information provided on the balance betweenbenefits and harms of a therapeutic intervention?

Output: newevidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may recommendationsor modify information provided on the balance betweenbenefits and harms of a therapeutic intervention?. ### Response: newevidence.


Instruction: What is the task force for the diagnosis and treatment of non-ST-segment elevationacute coronary syndromes of the European Society of Cardiology called?

Output: Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the task force for the diagnosis and treatment of non-ST-segment elevationacute coronary syndromes of the European Society of Cardiology called?. ### Response: Guidelines.


Instruction: When did EurHeart J.29:277–8.161 appear?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did EurHeart J.29:277–8.161 appear?. ### Response: 2008.


Instruction: What did Januzzi JL, Cannon CP, DiBattiste PM, et al. study?

Output: Effects of renal insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Januzzi JL, Cannon CP, DiBattiste PM, et al. study?. ### Response: Effects of renal insufficiency.