Instruction: What are the experiences/preferences of staff and p atients during transition between different heart failure care settings?

Output: competencies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the experiences/preferences of staff and p atients during transition between different heart failure care settings?. ### Response: competencies.


Instruction: What is the difference between different heart failure care settings?

Output: clinical and cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between different heart failure care settings?. ### Response: clinical and cost effectiveness.


Instruction: What are the differences between different care settings for heart failure?

Output: clinical and cost effectiveness of telemonitoring and self -monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between different care settings for heart failure?. ### Response: clinical and cost effectiveness of telemonitoring and self -monitoring.


Instruction: What is distinguished from patient-prosthesis mismatch by comparison with the early postoperative base-line study?

Output: Prosthetic valve stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is distinguished from patient-prosthesis mismatch by comparison with the early postoperative base-line study?. ### Response: Prosthetic valve stenosis.


Instruction: What is characterized by a clinical course of progressive increase in transvalvular velocity and pressure gradient?

Output: Prosthetic valve stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is characterized by a clinical course of progressive increase in transvalvular velocity and pressure gradient?. ### Response: Prosthetic valve stenosis.


Instruction: What is the term for abnormal thickened/calcified leaflets in bioprosthetic valves?

Output: Prosthetic valve stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for abnormal thickened/calcified leaflets in bioprosthetic valves?. ### Response: Prosthetic valve stenosis.


Instruction: What is best evaluated radiographically with fluoros-copy or cine-CT imaging?

Output: The motion of the leaflets of a mechanical valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is best evaluated radiographically with fluoros-copy or cine-CT imaging?. ### Response: The motion of the leaflets of a mechanical valve.


Instruction: Why do strong reflec-tions from the mechanical valve obscure motion on echocardiographic imaging in most patients?

Output: particularly as assessed on images from the trans-thoracic approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do strong reflec-tions from the mechanical valve obscure motion on echocardiographic imaging in most patients?. ### Response: particularly as assessed on images from the trans-thoracic approach.


Instruction: What must be adjusted to dem-ontrate leaflet motion from a side view?

Output: the angle of imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be adjusted to dem-ontrate leaflet motion from a side view?. ### Response: the angle of imaging.


Instruction: What is obtained at a high frame rate focused on the prosthetic valve in a 3D acquisition?

Output: Cine-CT images

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is obtained at a high frame rate focused on the prosthetic valve in a 3D acquisition?. ### Response: Cine-CT images.


Instruction: Cine-CT 3D images are compared with what?

Output: fluoroscopy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cine-CT 3D images are compared with what?. ### Response: fluoroscopy.


Instruction: What is more operator dependent than fluoroscopy?

Output: Cine-CT images

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more operator dependent than fluoroscopy?. ### Response: Cine-CT images.


Instruction: What allows detection of pannus or thrombus on or adjacent Table 23?

Output: cine-CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What allows detection of pannus or thrombus on or adjacent Table 23?. ### Response: cine-CT.


Instruction: Which type of Fibrinolysis is preferred over surgery for Prosthetic Valve Thrombosis?

Output: Systemic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which type of Fibrinolysis is preferred over surgery for Prosthetic Valve Thrombosis?. ### Response: Systemic.


Instruction: What type of thrombosis favors fibrinolysis?

Output: Systemic Fibrinolysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of thrombosis favors fibrinolysis?. ### Response: Systemic Fibrinolysis.


Instruction: What is low surgical risk?

Output: Readily available surgical expertise No surgical expertise available

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low surgical risk?. ### Response: Readily available surgical expertise No surgical expertise available.


Instruction: How long is a large clot?

Output: 0.8 cm2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is a large clot?. ### Response: 0.8 cm2.


Instruction: What is a small clot (0.8 cm2)?

Output: LA thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a small clot (0.8 cm2)?. ### Response: LA thrombus.


Instruction: What indicates coronary artery disease?

Output: CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates coronary artery disease?. ### Response: CAD.


Instruction: When was the 2017 VA/SCD Guideline published?

Output: September 25, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2017 VA/SCD Guideline published?. ### Response: September 25, 2018.


Instruction: What is the name of the guideline published by Al-Khatib and colleagues?

Output: VA/SCD Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline published by Al-Khatib and colleagues?. ### Response: VA/SCD Guideline.


Instruction: How many ventricular tachycardias are there after coronary artery bypass graft-ing?

Output: Monomorphic versus poly-morphic ventricular tachycardia after coronary artery bypass graft-ing. Am J Cardiol. 1995;75:403–5. S7.1.1.2-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ventricular tachycardias are there after coronary artery bypass graft-ing?. ### Response: Monomorphic versus poly-morphic ventricular tachycardia after coronary artery bypass graft-ing. Am J Cardiol. 1995;75:403–5. S7.1.1.2-3.


Instruction: What is a new onset sustained ventric-ular tachycardia after cardiac surgery?

Output: New-onset

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new onset sustained ventric-ular tachycardia after cardiac surgery?. ### Response: New-onset.


Instruction: What is the name of the trial investigators for the Coronary Artery Bypass Graft (CABG) Patch Trial?

Output: 3. Steinberg JS, Gaur A, Sciacca R, et al. New-onset sustained ventric-ular tachycardia after cardiac surgery. Circulation. 1999;99:903–8. S7.1.1.2-4. Bigger JT Jr. Prophylactic use of implanted cardiac defibrillators in patients at high risk for ventricular arrhythmias after coronary-artery bypass graft surgery. Coronary Artery Bypass Graft (CABG) Patch Trial Investigators. N Engl J Med. 1997;337:1569–75. S7.1.1.2-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial investigators for the Coronary Artery Bypass Graft (CABG) Patch Trial?. ### Response: 3. Steinberg JS, Gaur A, Sciacca R, et al. New-onset sustained ventric-ular tachycardia after cardiac surgery. Circulation. 1999;99:903–8. S7.1.1.2-4. Bigger JT Jr. Prophylactic use of implanted cardiac defibrillators in patients at high risk for ventricular arrhythmias after coronary-artery bypass graft surgery. Coronary Artery Bypass Graft (CABG) Patch Trial Investigators. N Engl J Med. 1997;337:1569–75. S7.1.1.2-5.


Instruction: What does CABG stand for?

Output: Coronary Artery Bypass Graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CABG stand for?. ### Response: Coronary Artery Bypass Graft.


Instruction: What is the name of the trial investigators that investigated CABG?

Output: Coronary Artery Bypass Graft (CABG) Patch Trial Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial investigators that investigated CABG?. ### Response: Coronary Artery Bypass Graft (CABG) Patch Trial Investigators.


Instruction: When was the N Engl J Med 337:1569-75 published?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 337:1569-75 published?. ### Response: 1997.


Instruction: How did CABG affect left ventricular ejection fraction?

Output: Effect of coronary artery bypass grafting on left ventricular ejection fraction in men eli-gible for implantable cardioverter-defibrillator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did CABG affect left ventricular ejection fraction?. ### Response: Effect of coronary artery bypass grafting on left ventricular ejection fraction in men eli-gible for implantable cardioverter-defibrillator.


Instruction: What is the risk of mortality after coronary artery revascularization in patients with left ventricular dysfunction and potential mortality?

Output: Early

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of mortality after coronary artery revascularization in patients with left ventricular dysfunction and potential mortality?. ### Response: Early.


Instruction: What is a risk factor for nonsustained ventricular tachycardia?

Output: revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for nonsustained ventricular tachycardia?. ### Response: revascularization.


Instruction: When was the J Cardiovasc Electrophysiol.13:342-6?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Cardiovasc Electrophysiol.13:342-6?. ### Response: 2002.


Instruction: What is a potential role of the wearable cardioverter defi-brillator?

Output: Early risk of mortality after coronary artery revascularization in patients with left ventricular dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential role of the wearable cardioverter defi-brillator?. ### Response: Early risk of mortality after coronary artery revascularization in patients with left ventricular dysfunction.


Instruction: What is primary prevention of SCD in Patients With Ischemic Heart Disease?

Output: S7.1.2-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is primary prevention of SCD in Patients With Ischemic Heart Disease?. ### Response: S7.1.2-1.


Instruction: What is an implantable cardioverter-defibrillator for?

Output: primary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an implantable cardioverter-defibrillator for?. ### Response: primary prevention.


Instruction: What does N Engl J Med. 2005:352:225-37. S7.1.2-2. Moss AJ, Zareba W, Hall WJ, et al. Prophylactic implantation of what in patients with myocardial infarction and reduced ejection fraction?

Output: a defibrillator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does N Engl J Med. 2005:352:225-37. S7.1.2-2. Moss AJ, Zareba W, Hall WJ, et al. Prophylactic implantation of what in patients with myocardial infarction and reduced ejection fraction?. ### Response: a defibrillator.


Instruction: What year did the N Engl J Med issue 335:1933-40?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the N Engl J Med issue 335:1933-40?. ### Response: 1996.


Instruction: What is the effect of implanted defibrillators on patients with coronary disease at high risk for ventricular arrhythmia?

Output: Improved survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of implanted defibrillators on patients with coronary disease at high risk for ventricular arrhythmia?. ### Response: Improved survival.


Instruction: What is the effect of risk strati-fication on the cost-effectiveness of the implantable cardioverter defi-brillator?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of risk strati-fication on the cost-effectiveness of the implantable cardioverter defi-brillator?. ### Response: Effect.


Instruction: What is a randomized study of the pre-vention of sudden death in patients with coronary artery disease?

Output: Multicenter Unsustained Tachycardia Trial Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomized study of the pre-vention of sudden death in patients with coronary artery disease?. ### Response: Multicenter Unsustained Tachycardia Trial Investigators.


Instruction: What causes death in patients with coronary artery disease?

Output: revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes death in patients with coronary artery disease?. ### Response: revascularization.


Instruction: What is the name of the multicenter unsustained tachycardia trial investigators?

Output: Multicenter Unsustained Tachycardia Trial Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter unsustained tachycardia trial investigators?. ### Response: Multicenter Unsustained Tachycardia Trial Investigators.


Instruction: When was the N Engl J Med.341:1882–90?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med.341:1882–90?. ### Response: 1999.


Instruction: How does a cardioverter defibrillator work?

Output: primary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does a cardioverter defibrillator work?. ### Response: primary prevention.


Instruction: Transplantation. 2013;45:3659-61. What is the name of the journal that deals with transplantation?

Output: Transplant Proc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Transplantation. 2013;45:3659-61. What is the name of the journal that deals with transplantation?. ### Response: Transplant Proc.


Instruction: Who is Frohlich GM, Holzmeister J, Hubler M, et al?

Output: Frohlich GM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Frohlich GM, Holzmeister J, Hubler M, et al?. ### Response: Frohlich GM.


Instruction: What risk of bias is taken into account in the analysis?

Output: /C15Repeating the analysis, excluding unpublished studies/C15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What risk of bias is taken into account in the analysis?. ### Response: /C15Repeating the analysis, excluding unpublished studies/C15.


Instruction: What type of studies are excluded to establish how much they dominate the results?

Output: very long or large

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of studies are excluded to establish how much they dominate the results?. ### Response: very long or large.


Instruction: What was the language of publication, source of funding, and country in which the study was conducted?

Output: industry vs.other

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the language of publication, source of funding, and country in which the study was conducted?. ### Response: industry vs.other.


Instruction: The available data were insufficient to determine the influ-ence of these factors on the effect size of critical and important outcomes?

Output: potassium binders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The available data were insufficient to determine the influ-ence of these factors on the effect size of critical and important outcomes?. ### Response: potassium binders.


Instruction: What approach assesses the quality of the evidence for each outcome across studies?

Output: GRADE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What approach assesses the quality of the evidence for each outcome across studies?. ### Response: GRADE.


Instruction: How is the overall quality of evidence related to each critical and important outcome assessed?

Output: using the GRADE approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the overall quality of evidence related to each critical and important outcome assessed?. ### Response: using the GRADE approach.


Instruction: What is the GRADE approach?

Output: assesses the qualityof the evidence for each outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the GRADE approach?. ### Response: assesses the qualityof the evidence for each outcome.


Instruction: What is the initial grade for the quality of the evidence for each outcome?

Output: high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the initial grade for the quality of the evidence for each outcome?. ### Response: high.


Instruction: For outcomes that are based ondata from RCTs, what is considered to be high?

Output: the initial grade for the quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For outcomes that are based ondata from RCTs, what is considered to be high?. ### Response: the initial grade for the quality of the evidence.


Instruction: What is considered low for observational studies?

Output: initial quality ofthe evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered low for observational studies?. ### Response: initial quality ofthe evidence.


Instruction: What is lowered in the event of study limitations?

Output: The quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lowered in the event of study limitations?. ### Response: The quality of the evidence.


Instruction: What is important inconsistencies in results across?

Output: Guideline Chapter 4 Blood pressure management in kidney transplant recipients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important inconsistencies in results across?. ### Response: Guideline Chapter 4 Blood pressure management in kidney transplant recipients.


Instruction: What are some examples of non-RAS inhibition?

Output: alpha-blockers, beta-blockers,CCBs, diuretics, DRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some examples of non-RAS inhibition?. ### Response: alpha-blockers, beta-blockers,CCBs, diuretics, DRI.


Instruction: What is another name for antihypertensive treatment?

Output: Intervention RAS inhibition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for antihypertensive treatment?. ### Response: Intervention RAS inhibition.


Instruction: What does the Cochrane Database of Systematic Reviews recommend for kidney transplant recipients?

Output: Antihypertensive treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Cochrane Database of Systematic Reviews recommend for kidney transplant recipients?. ### Response: Antihypertensive treatment.


Instruction: What is the primary benefit of using potassium binders compared to placebo?

Output: improve clinically relevant outcomes and decrease adverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary benefit of using potassium binders compared to placebo?. ### Response: improve clinically relevant outcomes and decrease adverse effects.


Instruction: What is the name of the drug used to treat kidney transplant recipients with chronic hyperkalaemia?

Output: potassium binders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat kidney transplant recipients with chronic hyperkalaemia?. ### Response: potassium binders.


Instruction: What are the names of the drugs used in the study design RCTs?

Output: ACEi, ARB, aldosterone antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the drugs used in the study design RCTs?. ### Response: ACEi, ARB, aldosterone antagonists.


Instruction: What is the name of the Cochrane Database of Systematic Reviews?

Output: 2009:3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Cochrane Database of Systematic Reviews?. ### Response: 2009:3.


Instruction: What does a lower BP target do in children with CKD?

Output: improve ef ﬁcacy outcomes and reduceadverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a lower BP target do in children with CKD?. ### Response: improve ef ﬁcacy outcomes and reduceadverse effects.


Instruction: What is an additional medication that can be used in patients with long QT syndrome?

Output: Mexiletine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an additional medication that can be used in patients with long QT syndrome?. ### Response: Mexiletine.


Instruction: What is a shortening of the QTc used to reduce?

Output: recurrent arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a shortening of the QTc used to reduce?. ### Response: recurrent arrhythmias.


Instruction: What can be used in patients with long QT syndrome and recurrent ICD shocks?

Output: Mexiletine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used in patients with long QT syndrome and recurrent ICD shocks?. ### Response: Mexiletine.


Instruction: Left cardiac sympa-thetic denervation is associated with a reduc-tion of what?

Output: the number of appropriate ICD shocks and VA burden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Left cardiac sympa-thetic denervation is associated with a reduc-tion of what?. ### Response: the number of appropriate ICD shocks and VA burden.


Instruction: What has been correlated with reduced risk of VA burden?

Output: Left cardiac sympa-thetic denervation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been correlated with reduced risk of VA burden?. ### Response: Left cardiac sympa-thetic denervation.


Instruction: What has been correlated with reduced risk of recurrent ICD shocks and frequence of symptoms?

Output: Reduction of the QTc to  <500 ms after left cardiac sympa-thetic denervation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been correlated with reduced risk of recurrent ICD shocks and frequence of symptoms?. ### Response: Reduction of the QTc to  <500 ms after left cardiac sympa-thetic denervation.


Instruction: SCD or SCA is reported in what percentage of patients?

Output: 3% to 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: SCD or SCA is reported in what percentage of patients?. ### Response: 3% to 10%.


Instruction: What percentage of high-risk patients experience at least 1 recurrence?

Output: 27%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of high-risk patients experience at least 1 recurrence?. ### Response: 27%.


Instruction: How many recurrences do high-risk patients experience?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many recurrences do high-risk patients experience?. ### Response: 1.


Instruction: Where is the left cardiac sym-pathetic denervation performed?

Output: centers with surgical expertise in this procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the left cardiac sym-pathetic denervation performed?. ### Response: centers with surgical expertise in this procedure.


Instruction: What guideline guides the use of additional medications?

Output: long QT Figure 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What guideline guides the use of additional medications?. ### Response: long QT Figure 11.


Instruction: What type of syndrome is Long QT syndrome type 3?

Output: Long QT syndrome type 2.Figure 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of syndrome is Long QT syndrome type 3?. ### Response: Long QT syndrome type 2.Figure 12.


Instruction: When was the article published?

Output: September 25, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the article published?. ### Response: September 25, 2018.


Instruction: What is the 2015 ACC/AHA/HRS SVT Guideline e563 234?

Output: Page et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2015 ACC/AHA/HRS SVT Guideline e563 234?. ### Response: Page et al.


Instruction: What does Mehta D, Wafa S, Ward DE, et al. do in the termination of junctional tachycardia?

Output: Relative efficacy of various physi-cal manoeuvres

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Mehta D, Wafa S, Ward DE, et al. do in the termination of junctional tachycardia?. ### Response: Relative efficacy of various physi-cal manoeuvres.


Instruction: What are the determinants of vagal maneuvers for termination of paroxysmal supra-ventricular tachycardia?

Output: Electrophysiological mechanisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the determinants of vagal maneuvers for termination of paroxysmal supra-ventricular tachycardia?. ### Response: Electrophysiological mechanisms.


Instruction: What is Glatter KA's title?

Output: Electrophysiologic effects of adenosine in patients with supraventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Glatter KA's title?. ### Response: Electrophysiologic effects of adenosine in patients with supraventricular tachycardia.


Instruction: How does adenosine affect patients with supraventricular Tachycatarrhics?

Output: Electrophysiologic effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does adenosine affect patients with supraventricular Tachycatarrhics?. ### Response: Electrophysiologic effects.


Instruction: When did Dougherty AH, Jackman WM, Naccarelli GV, et al. develop acute conversion of acetylcholine?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Dougherty AH, Jackman WM, Naccarelli GV, et al. develop acute conversion of acetylcholine?. ### Response: 1999.


Instruction: What drug is used to treat paroxysmal supraventricular tachycardia?

Output: apamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used to treat paroxysmal supraventricular tachycardia?. ### Response: apamil.


Instruction: What is the name of the study group that studies the use of diltiazem?

Output: IV Diltiazem Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studies the use of diltiazem?. ### Response: IV Diltiazem Study Group.


Instruction: When was the Am J Cardiol.70:587–92 published?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol.70:587–92 published?. ### Response: 1992.


Instruction: What is the difference between paroxysmal supraventricular tachycardia and atrial fibril-lation or flutter?

Output: control of ven-tricular rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between paroxysmal supraventricular tachycardia and atrial fibril-lation or flutter?. ### Response: control of ven-tricular rate.


Instruction: What was the outcome of the double-blind randomized cross-over study?

Output: control of ven-tricular rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the double-blind randomized cross-over study?. ### Response: control of ven-tricular rate.


Instruction: When was the Ann Intern Med 94:1–6. 239?

Output: 1981

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Intern Med 94:1–6. 239?. ### Response: 1981.


Instruction: What is esmolol used for in patients with supraventricular tachyarrhythmias?

Output: treatment and transfer of patients with supraventricular tachyarrhythmias to alternate oral antiarrhythmic agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is esmolol used for in patients with supraventricular tachyarrhythmias?. ### Response: treatment and transfer of patients with supraventricular tachyarrhythmias to alternate oral antiarrhythmic agents.


Instruction: What is the name of the drug that is used in the treatment and transfer of patients?

Output: esmolol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used in the treatment and transfer of patients?. ### Response: esmolol.


Instruction: When did the J Clin Pharmacol. 1988 issue?

Output: 28:746–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Clin Pharmacol. 1988 issue?. ### Response: 28:746–.


Instruction: What is the name of the drug used to treat paroxysmal supraventricular tachycardia?

Output: Verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat paroxysmal supraventricular tachycardia?. ### Response: Verapamil.


Instruction: When was the J Am Coll Cardiol 37:548–53?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 37:548–53?. ### Response: 2001.


Instruction: What is diltiazem used for?

Output: Acute conversion of paroxysmal supraventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is diltiazem used for?. ### Response: Acute conversion of paroxysmal supraventricular tachycardia.


Instruction: What is a paroxysmal supraven-tricular tachycardia with a single oral dose of diltiazem and propranolol?

Output: Termination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a paroxysmal supraven-tricular tachycardia with a single oral dose of diltiazem and propranolol?. ### Response: Termination.


Instruction: What does Rinkenberger RL, Prystowsky EN, Heger JJ, et al. do?

Output: Effects of intravenous and chronic oral verapamil administration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Rinkenberger RL, Prystowsky EN, Heger JJ, et al. do?. ### Response: Effects of intravenous and chronic oral verapamil administration.


Instruction: What is the long-term outcome of patients with atrioventricular node reentrant tachycardia?

Output: 244. D’Este D, Zoppo F, Bertaglia E, et al. Long-term outcome of patients with atrioventricular node reentrant tachycardia. Int J Cardiol. 2007;115:350–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term outcome of patients with atrioventricular node reentrant tachycardia?. ### Response: 244. D’Este D, Zoppo F, Bertaglia E, et al. Long-term outcome of patients with atrioventricular node reentrant tachycardia. Int J Cardiol. 2007;115:350–.


Instruction: Int J Cardiol. 2007;115:350–3. 245. Langberg JJ, Leon A, Borganelli M, et al. Arandomized, prospective comparison of anterior and posterior approaches to radiofrequency cath-eter ablation of what?

Output: atrioventricular nodal reentry tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol. 2007;115:350–3. 245. Langberg JJ, Leon A, Borganelli M, et al. Arandomized, prospective comparison of anterior and posterior approaches to radiofrequency cath-eter ablation of what?. ### Response: atrioventricular nodal reentry tachycardia.


Instruction: Circulation. 1993;87:1551–6.

Output: 246

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 1993;87:1551–6.. ### Response: 246.


Instruction: What is cath-eter ablation of?

Output: atrioventricular nodal reentry tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cath-eter ablation of?. ### Response: atrioventricular nodal reentry tachycardia.


Instruction: What is atrioventricular nodal reentry tachycardia?

Output: slow pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atrioventricular nodal reentry tachycardia?. ### Response: slow pathway.


Instruction: When did Circulation. 1993:87:1551–6.

Output: 246

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 1993:87:1551–6.. ### Response: 246.


Instruction: What was a randomized com-parison of anatomic and electrogram mapping approaches?

Output: ablation of the slow pathway of atrioventricular node reentrant tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a randomized com-parison of anatomic and electrogram mapping approaches?. ### Response: ablation of the slow pathway of atrioventricular node reentrant tachycardia.


Instruction: What year did Cardiol. 1994:23:716–23. 247?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Cardiol. 1994:23:716–23. 247?. ### Response: 1994.


Instruction: What is the name of the procedure used to select radiofrequency ablation?

Output: Randomized com-parison of anatomic and electrogram mapping

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used to select radiofrequency ablation?. ### Response: Randomized com-parison of anatomic and electrogram mapping.


Instruction: What is likely to be sufficient?

Output: low certainty in the evidence about effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to be sufficient?. ### Response: low certainty in the evidence about effects.


Instruction: Why should protamine primarily be used for patients on UFH?

Output: due to completerather than partial reversal of the anticoagulant effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why should protamine primarily be used for patients on UFH?. ### Response: due to completerather than partial reversal of the anticoagulant effect.


Instruction: What did most studies not specify?

Output: whether “heparin ”included UFH or LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did most studies not specify?. ### Response: whether “heparin ”included UFH or LMWH.


Instruction: What is the effect of protamine administration on life-threatening bleeding in VTE?

Output: comparative effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of protamine administration on life-threatening bleeding in VTE?. ### Response: comparative effectiveness.


Instruction: What does UFH/LMWH do for patients who have been treated with LMWH?

Output: cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does UFH/LMWH do for patients who have been treated with LMWH?. ### Response: cessation.


Instruction: What should patients receiving anticoagulant treatment of VTE do if they survive an episode of major bleeding?

Output: resumption oforal anticoagulation therapy vs discontinuation of oral anticoagu-lation therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients receiving anticoagulant treatment of VTE do if they survive an episode of major bleeding?. ### Response: resumption oforal anticoagulation therapy vs discontinuation of oral anticoagu-lation therapy.


Instruction: What does the ASH guidelinepanel suggest?

Output: resumption of oral anticoagulation therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ASH guidelinepanel suggest?. ### Response: resumption of oral anticoagulation therapy.


Instruction: What does the guidelinepanel recommend?

Output: resumption of oral anticoagulation therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the guidelinepanel recommend?. ### Response: resumption of oral anticoagulation therapy.


Instruction: What is the conditional recommendation based on?

Output: very low certainty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the conditional recommendation based on?. ### Response: very low certainty.


Instruction: Who is at moderate to high risk for recurrent VTE?

Output: pa-tients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is at moderate to high risk for recurrent VTE?. ### Response: pa-tients.


Instruction: What are patients at moderate to high risk for recurrent VTE?

Output: anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients at moderate to high risk for recurrent VTE?. ### Response: anticoagulation.


Instruction: Are patients willing to continue anti-coagulation therapy?

Output: patients who did and did not resume anticoagulation therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Are patients willing to continue anti-coagulation therapy?. ### Response: patients who did and did not resume anticoagulation therapy.


Instruction: What was included in the most recent systematic review?

Output: eligible studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was included in the most recent systematic review?. ### Response: eligible studies.


Instruction: What is the term for gastrointestinal tract bleeding?

Output: GIB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for gastrointestinal tract bleeding?. ### Response: GIB.


Instruction: How many observational studies were there in 2014?

Output: 17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many observational studies were there in 2014?. ### Response: 17.


Instruction: What was the total number of studies?

Output: 17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the total number of studies?. ### Response: 17.


Instruction: How long did follow-up period vary between studies?

Output: 3 months to 10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did follow-up period vary between studies?. ### Response: 3 months to 10 years.


Instruction: How many studies reported the effect of anticoagulation therapy resumption on all-cause mortality?

Output: Six studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies reported the effect of anticoagulation therapy resumption on all-cause mortality?. ### Response: Six studies.


Instruction: What did studies report the development of?

Output: thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did studies report the development of?. ### Response: thromboembolism.


Instruction: How many studies reported development of thromboembolism?

Output: 23012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies reported development of thromboembolism?. ### Response: 23012.


Instruction: What is shown online at https://dbep.gradepro.org/profile/098f8dae?

Output: EtD frame-work

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shown online at https://dbep.gradepro.org/profile/098f8dae?. ### Response: EtD frame-work.


Instruction: What was associated with reduced risk of all-cause mortality?

Output: Resuming anticoagulation following GIB or ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with reduced risk of all-cause mortality?. ### Response: Resuming anticoagulation following GIB or ICH.


Instruction: How many fewer deaths per 1000 were associated with a resumption of anticoagulation?

Output: 165

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many fewer deaths per 1000 were associated with a resumption of anticoagulation?. ### Response: 165.


Instruction: What are oral anticoagulants versus warfarin in patients with atrial fibrillation and valvular heart disease?

Output: Apixaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are oral anticoagulants versus warfarin in patients with atrial fibrillation and valvular heart disease?. ### Response: Apixaban.


Instruction: What is the name of the systematic review and meta-analysis in which anticoagulant is used in patients?

Output: ARISTOTLE trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis in which anticoagulant is used in patients?. ### Response: ARISTOTLE trial.


Instruction: When was the J Am Heart Assoc 2017 published?

Output: 6:e005835

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Heart Assoc 2017 published?. ### Response: 6:e005835.


Instruction: Atrial fibrillation and valvular heart disease: evaluating what in a nationwide cohort study?

Output: valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation and valvular heart disease: evaluating what in a nationwide cohort study?. ### Response: valvular heart disease.


Instruction: Europace. 2019;21: 33-40.

Output: 2. Lip GYH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Europace. 2019;21: 33-40.. ### Response: 2. Lip GYH.


Instruction: Vora AN, Dai D, Matsuoka R, et al. Incidence, management, and associated clinical outcomes of new-onset atrial fibrosis following transcath-eter aortic valve replacement: an analysis from what registry?

Output: STS/ACC TVT registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Vora AN, Dai D, Matsuoka R, et al. Incidence, management, and associated clinical outcomes of new-onset atrial fibrosis following transcath-eter aortic valve replacement: an analysis from what registry?. ### Response: STS/ACC TVT registry.


Instruction: What is the STS/ACC TVT registry used for?

Output: an analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the STS/ACC TVT registry used for?. ### Response: an analysis.


Instruction: What does Apixaban do in patients with atrial fibrillation after transfemoral aortic valve replacement?

Output: preven-tion of thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Apixaban do in patients with atrial fibrillation after transfemoral aortic valve replacement?. ### Response: preven-tion of thromboembolism.


Instruction: Which type of anticoagulant type does Barbanti M have?

Output: Oral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which type of anticoagulant type does Barbanti M have?. ### Response: Oral.


Instruction: What type of anticoagulant type and outcomes after transcatheter aortic valve replacement?

Output: Oral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of anticoagulant type and outcomes after transcatheter aortic valve replacement?. ### Response: Oral.


Instruction: What is the JACC Cardiovasc Interv. 2019;12:1566–76?

Output: Oral anticoagulant type and outcomes after transcatheter aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JACC Cardiovasc Interv. 2019;12:1566–76?. ### Response: Oral anticoagulant type and outcomes after transcatheter aortic valve replacement.


Instruction: What is the impact of postoperative anticoagulant management on outcome in patients with atrial fibrillation?

Output: Continued versus interrupted oral anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of postoperative anticoagulant management on outcome in patients with atrial fibrillation?. ### Response: Continued versus interrupted oral anticoagulation.


Instruction: What is Eikelboom JW, Connolly SJ, Brueckmann M, et al. Using Dabigatran ver -sus warfarin in mechanical heart valves?

Output: 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Eikelboom JW, Connolly SJ, Brueckmann M, et al. Using Dabigatran ver -sus warfarin in mechanical heart valves?. ### Response: 7.


Instruction: What is the name of the ENGAGE AF-TIMI 48 trial?

Output: J Am Coll Car -diol. 2017;69

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ENGAGE AF-TIMI 48 trial?. ### Response: J Am Coll Car -diol. 2017;69.


Instruction: What drug is used to prevent thromboembolism in patients with valvular heart disease?

Output: edoxaban or warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used to prevent thromboembolism in patients with valvular heart disease?. ### Response: edoxaban or warfarin.


Instruction: What is edoxaban used for in patients with atrial fibrillation and bioprosthetic valves?

Output: preven-tion of thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is edoxaban used for in patients with atrial fibrillation and bioprosthetic valves?. ### Response: preven-tion of thromboembolism.


Instruction: What is the Circulation 2017135:1273–5?

Output: Edoxaban for the preven-tion of thromboembolism in patients with atrial fibrillation and biopros-thetic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Circulation 2017135:1273–5?. ### Response: Edoxaban for the preven-tion of thromboembolism in patients with atrial fibrillation and biopros-thetic valves.


Instruction: How does apixaban compare to war -farin?

Output: Efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does apixaban compare to war -farin?. ### Response: Efficacy and safety.


Instruction: What is ARISTOTLE?

Output: Apixaban for Reduction in Stroke and Other Thromboem-bolic Events in Atrial Fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ARISTOTLE?. ### Response: Apixaban for Reduction in Stroke and Other Thromboem-bolic Events in Atrial Fibrillation.


Instruction: What is apixa-ban vs warfarin used for?

Output: Reduction in Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is apixa-ban vs warfarin used for?. ### Response: Reduction in Stroke.


Instruction: What did the ARISTOTLE trial provide insights from?

Output: Efficacy and safety of apixa-ban vs warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ARISTOTLE trial provide insights from?. ### Response: Efficacy and safety of apixa-ban vs warfarin.


Instruction: What was the name of the study that provided insights into atrial fibrillation and valve repair?

Output: ARISTOTLE trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that provided insights into atrial fibrillation and valve repair?. ### Response: ARISTOTLE trial.


Instruction: How many patients were enrolled in the ARistOTLE study?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the ARistOTLE study?. ### Response: 11.


Instruction: What is rivaroxaban vs. warfarin used for in patients with non-valvular atrial fibrillation?

Output: Native valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rivaroxaban vs. warfarin used for in patients with non-valvular atrial fibrillation?. ### Response: Native valve disease.


Instruction: What is the name of the drug used to treat aortic valve disease?

Output: rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat aortic valve disease?. ### Response: rivaroxaban.


Instruction: Baddour et al Infective Endocarditis in Adults 1445for native valve treatment?

Output: 3. It is reasonable to obtain at least 2 sets of blood cul-tures every 24 to 48 hours until bloodstream infec-tion has cleared (Class IIa; Level of Evidence C).4. If operative tissue cultures are positive, then an entire antimicrobial course is reasonable after valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Baddour et al Infective Endocarditis in Adults 1445for native valve treatment?. ### Response: 3. It is reasonable to obtain at least 2 sets of blood cul-tures every 24 to 48 hours until bloodstream infec-tion has cleared (Class IIa; Level of Evidence C).4. If operative tissue cultures are positive, then an entire antimicrobial course is reasonable after valve surgery.


Instruction: In regimens that contain combi-nation antimicrobial therapy, how should agents be administered at the same time or temporally close together?

Output: it is reasonable to administer agents at the same time or temporally close together

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In regimens that contain combi-nation antimicrobial therapy, how should agents be administered at the same time or temporally close together?. ### Response: it is reasonable to administer agents at the same time or temporally close together.


Instruction: What should be obtained to define an optimal empirical treatment regimen at the time of initiation of antimicrobial therapy?

Output: Infectious diseases consultation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be obtained to define an optimal empirical treatment regimen at the time of initiation of antimicrobial therapy?. ### Response: Infectious diseases consultation.


Instruction: What is reasonable that the counting of days for the duration of antibiotic therapy begin on the first day?

Output: blood cultures are negative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable that the counting of days for the duration of antibiotic therapy begin on the first day?. ### Response: blood cultures are negative.


Instruction: When should antimicrobial therapy begin?

Output: first day on which blood cultures are negative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should antimicrobial therapy begin?. ### Response: first day on which blood cultures are negative.


Instruction: How many sets of blood cultures should be obtained every 24 to 48 hours?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sets of blood cultures should be obtained every 24 to 48 hours?. ### Response: 2.


Instruction: How many times a day are blood cultures done?

Output: 2 sets of blood cul-tures every 24 to 48 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times a day are blood cultures done?. ### Response: 2 sets of blood cul-tures every 24 to 48 hours.


Instruction: What is a Class IIa; Level of Evidence C?

Output: blood cultures are negative in cases in which blood cultures were initially positive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Class IIa; Level of Evidence C?. ### Response: blood cultures are negative in cases in which blood cultures were initially positive.


Instruction: If operative tissue cultures are positive, an entire antimicrobial course is reasonable after what?

Output: valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If operative tissue cultures are positive, an entire antimicrobial course is reasonable after what?. ### Response: valve surgery.


Instruction: What may be reasonable to count the number of days of anti-microbial therapy administered before surgery in the overall duration of therapy?

Output: operative tissue cultures are negative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable to count the number of days of anti-microbial therapy administered before surgery in the overall duration of therapy?. ### Response: operative tissue cultures are negative.


Instruction: What is reasonable to time the administration of antimi-crobial therapy at the same time?

Output: temporally close together

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to time the administration of antimi-crobial therapy at the same time?. ### Response: temporally close together.


Instruction: How many antimicrobial agents are included in a regimen?

Output: >1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many antimicrobial agents are included in a regimen?. ### Response: >1.


Instruction: What type of exposure to contaminated milk or infected farm animals can lead to infection?

Output: Dog or cat

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of exposure to contaminated milk or infected farm animals can lead to infection?. ### Response: Dog or cat.


Instruction: What does Brucella spCoxiella burnetiiErysipelothrix sppHomeless, body lice?

Output: Contact with contaminated milk or infected farm animals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Brucella spCoxiella burnetiiErysipelothrix sppHomeless, body lice?. ### Response: Contact with contaminated milk or infected farm animals.


Instruction: What does VGS stand for?

Output: viridans group streptococci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does VGS stand for?. ### Response: viridans group streptococci.


Instruction: Which species indicates Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens?

Output: HACEK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which species indicates Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens?. ### Response: HACEK.


Instruction: What does IDU stand for?

Output: injection drug use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does IDU stand for?. ### Response: injection drug use.


Instruction: What is the name of the Viridans group streptococci?

Output: VGS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Viridans group streptococci?. ### Response: VGS.


Instruction: What is one of the major causes of pregnancy, delivery, and abortion?

Output: Genitourinary disorders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the major causes of pregnancy, delivery, and abortion?. ### Response: Genitourinary disorders.


Instruction: What is another cause of skin disorders, including recurrent infections?

Output: Chronic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another cause of skin disorders, including recurrent infections?. ### Response: Chronic.


Instruction: What is an update on Italian Stroke Organization guidelines on carotid endarterectomy and stenting?

Output: Lanza G, Ricci S, Setacci C, Castelli P, Novalil C, Pratesi C, Speziale F, Cremonesi A, Morlacchi E, Lanza J, et al. An update on Italian Stroke Organization guidelines on carotid endarterectomy and stenting. Int J Stroke. 2014;9(suppl A100):14–19. doi: 10.1111/ijs.12226 517. Kakisis JD, Avgerinos ED, Antonopoulos CN, Giannakopoulos TG, Moulakakis K, Liapis CD. The European Society for Vascular Surgery guidelines for carotid intervention: an updated independent assessment and literature review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an update on Italian Stroke Organization guidelines on carotid endarterectomy and stenting?. ### Response: Lanza G, Ricci S, Setacci C, Castelli P, Novalil C, Pratesi C, Speziale F, Cremonesi A, Morlacchi E, Lanza J, et al. An update on Italian Stroke Organization guidelines on carotid endarterectomy and stenting. Int J Stroke. 2014;9(suppl A100):14–19. doi: 10.1111/ijs.12226 517. Kakisis JD, Avgerinos ED, Antonopoulos CN, Giannakopoulos TG, Moulakakis K, Liapis CD. The European Society for Vascular Surgery guidelines for carotid intervention: an updated independent assessment and literature review.


Instruction: What are the European Society for Vascular Surgery guidelines for carotid intervention: an updated independent assessment and literature review?

Output: 2012;44:238–243

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the European Society for Vascular Surgery guidelines for carotid intervention: an updated independent assessment and literature review?. ### Response: 2012;44:238–243.


Instruction: How many 2011 guidelines were reviewed?

Output: five

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many 2011 guidelines were reviewed?. ### Response: five.


Instruction: What is a comparison of the five 2011 guidelines?

Output: carotid stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison of the five 2011 guidelines?. ### Response: carotid stenosis.


Instruction: How many guidelines were there in 2011 for the treatment of carotid stenosis?

Output: five

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many guidelines were there in 2011 for the treatment of carotid stenosis?. ### Response: five.


Instruction: What is the name of the 2011 guideline on the management of the disease?

Output: ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2011 guideline on the management of the disease?. ### Response: ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline.


Instruction: What is the name of the 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVS guideline on the management of patients with extracranial carotid and verte-bral artery disease?

Output: 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVS guideline on the management of patients with extracranial carotid and verte-bral artery disease?. ### Response: 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline.


Instruction: What are ARBs?

Output: Angiotensin-receptor blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ARBs?. ### Response: Angiotensin-receptor blockers.


Instruction: What are beta blockers recom-mended in patients with angina pectoris, a history of MI, orLV dysfunction?

Output: Angiotensin-receptor blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are beta blockers recom-mended in patients with angina pectoris, a history of MI, orLV dysfunction?. ### Response: Angiotensin-receptor blockers.


Instruction: Aldosterone antagonists improve the prognosis in what?

Output: patients with LV dysfunction and heart fail-ure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aldosterone antagonists improve the prognosis in what?. ### Response: patients with LV dysfunction and heart fail-ure.


Instruction: What are useful in the treatment of angina?

Output: Calcium antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are useful in the treatment of angina?. ### Response: Calcium antagonists.


Instruction: What will many patients with SIHD require to achieve optimal BP control?

Output: a combinationof drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will many patients with SIHD require to achieve optimal BP control?. ### Response: a combinationof drugs.


Instruction: What is the effectiveness of routine echocardiography to guide treatment selection for prevention of recurrent stroke uncertain?

Output: not recommended

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effectiveness of routine echocardiography to guide treatment selection for prevention of recurrent stroke uncertain?. ### Response: not recommended.


Instruction: What is reasonable to screen all patients for after AIS?

Output: diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to screen all patients for after AIS?. ### Response: diabetes mellitus.


Instruction: After AIS, it is reasonable to screen all patients for diabetes mellitus with testing of fasting plasma glucose, hemoglobin A1c, or an oral glucose tolerance test?

Output: hemoglobin A1c

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After AIS, it is reasonable to screen all patients for diabetes mellitus with testing of fasting plasma glucose, hemoglobin A1c, or an oral glucose tolerance test?. ### Response: hemoglobin A1c.


Instruction: Choice of test and timing should be guided by what?

Output: clinical judgment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Choice of test and timing should be guided by what?. ### Response: clinical judgment.


Instruction: What may temporarily perturb measures of plasma glucose?

Output: acute illness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may temporarily perturb measures of plasma glucose?. ### Response: acute illness.


Instruction: What may be more accurate than other screening tests in the immediate postevent period?

Output: hemoglobin A1c

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be more accurate than other screening tests in the immediate postevent period?. ### Response: hemoglobin A1c.


Instruction: What is COR unchanged?

Output: LOE amended to conform with ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is COR unchanged?. ### Response: LOE amended to conform with ACC/AHA 2015 Recommendation Classification System.


Instruction: What is LOE amended to conform with?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LOE amended to conform with?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: Where is Table XCV located?

Output: online Data Supplement 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Table XCV located?. ### Response: online Data Supplement 1.


Instruction: What is unknown about screening for thrombophilic states in stroke patients?

Output: The usefulness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unknown about screening for thrombophilic states in stroke patients?. ### Response: The usefulness.


Instruction: What was reworded for clarity from 2014 Secondary Prevention?

Output: IIb C-LDRecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reworded for clarity from 2014 Secondary Prevention?. ### Response: IIb C-LDRecommendation.


Instruction: How was LOE amended to conform with ACC/AHA 2015?

Output: Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was LOE amended to conform with ACC/AHA 2015?. ### Response: Recommendation Classification System.


Instruction: What should not be ordered for the evaluation of MI, stroke, or peripheral arterial thrombosis?

Output: tests for inherited thrombophilia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be ordered for the evaluation of MI, stroke, or peripheral arterial thrombosis?. ### Response: tests for inherited thrombophilia.


Instruction: What is OSA?

Output: obstructive sleep apnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is OSA?. ### Response: obstructive sleep apnea.


Instruction: What is not recommended for patients with recent ischemic stroke?

Output: Routine screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for patients with recent ischemic stroke?. ### Response: Routine screening.


Instruction: What is the most effective medical therapy for OSA?

Output: Continuous positive airway pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most effective medical therapy for OSA?. ### Response: Continuous positive airway pressure.


Instruction: How long after AIS did a small RCT of CPAP start in 127 patients?

Output: 4.6±2.8 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after AIS did a small RCT of CPAP start in 127 patients?. ### Response: 4.6±2.8 days.


Instruction: How many patients started 4.62.8 days after AIS showed mixed results with no effect on disability, total cardiovascular events, cardiovascular mortality, or cardiovascular event–free survival?

Output: 127

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients started 4.62.8 days after AIS showed mixed results with no effect on disability, total cardiovascular events, cardiovascular mortality, or cardiovascular event–free survival?. ### Response: 127.


Instruction: What did the trial not specify?

Output: a primary end point

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the trial not specify?. ### Response: a primary end point.


Instruction: The trial did not specify a primary end point and compared multiple different end points.

Output: 371

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The trial did not specify a primary end point and compared multiple different end points.. ### Response: 371.


Instruction: What did not specify a primary end point and compared multiple different outcomes at multiple time points?

Output: A small RCT of CPAP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not specify a primary end point and compared multiple different outcomes at multiple time points?. ### Response: A small RCT of CPAP.


Instruction: What does pre-operative aspirin decrease?

Output: platelet aggregation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does pre-operative aspirin decrease?. ### Response: platelet aggregation.


Instruction: What is the name of the study that has been conducted in a placebo controlled, double-blind clinical trial?

Output: Nippon Kyobu Geka Gakkai Zasshi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that has been conducted in a placebo controlled, double-blind clinical trial?. ### Response: Nippon Kyobu Geka Gakkai Zasshi.


Instruction: How many patients were in the post-operative blood loss trial?

Output: 100

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were in the post-operative blood loss trial?. ### Response: 100.


Instruction: What is the name of the double-blind, placebo controlled, clinical trial in 100 patients with chronic stable angina?

Output: Pre-operative aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the double-blind, placebo controlled, clinical trial in 100 patients with chronic stable angina?. ### Response: Pre-operative aspirin.


Instruction: When was the Eur J Cardiothorac Surg.8:404–9.1097?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur J Cardiothorac Surg.8:404–9.1097?. ### Response: 1994.


Instruction: What is the name of the company that specializes in bypassgrafting?

Output: Nippon Kyobu Geka Gakkai Zasshi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the company that specializes in bypassgrafting?. ### Response: Nippon Kyobu Geka Gakkai Zasshi.


Instruction: When was the last issue of Nippon Kyobu Geka Gakkai Zasshi published?

Output: 71.1101

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of Nippon Kyobu Geka Gakkai Zasshi published?. ### Response: 71.1101.


Instruction: What is a role of aspirin and platelet glycoprotein IIIa polymorphism?

Output: Prediction of the excessiveperioperative bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a role of aspirin and platelet glycoprotein IIIa polymorphism?. ### Response: Prediction of the excessiveperioperative bleeding.


Instruction: What is the effect of preoperativeaspirin use on bleeding, transfusion, myocardial infarction, and mortality incoronary artery bypass surgery?

Output: decreasesplatelet aggregation and increases post-operative blood loss

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of preoperativeaspirin use on bleeding, transfusion, myocardial infarction, and mortality incoronary artery bypass surgery?. ### Response: decreasesplatelet aggregation and increases post-operative blood loss.


Instruction: What is a systematic review of randomized andobservational studies?

Output: The effect of pre-operative aspirinon bleeding, transfusion, myocardial infarction, and mortality incoronary artery bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of randomized andobservational studies?. ### Response: The effect of pre-operative aspirinon bleeding, transfusion, myocardial infarction, and mortality incoronary artery bypass surgery.


Instruction: What is clopidogrel used for aftercoronary artery bypass surgery?

Output: bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel used for aftercoronary artery bypass surgery?. ### Response: bleeding.


Instruction: What is the name of the systematic review of randomized andobservational studies?

Output: The effect of pre-operative aspirinon bleeding, transfusion, myocardial infarction, and mortality incoronary artery bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of randomized andobservational studies?. ### Response: The effect of pre-operative aspirinon bleeding, transfusion, myocardial infarction, and mortality incoronary artery bypass surgery.


Instruction: When was the Eur Heart J. 2008 published?

Output: 29:1057–71.1101

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur Heart J. 2008 published?. ### Response: 29:1057–71.1101.


Instruction: What type of revascularization is used after clopidogrel antiplatelet therapy?

Output: Urgent or emergentcoronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of revascularization is used after clopidogrel antiplatelet therapy?. ### Response: Urgent or emergentcoronary.


Instruction: What year did Thorac Cardiovasc Surg issue 51:185–9.1103?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Thorac Cardiovasc Surg issue 51:185–9.1103?. ### Response: 2003.


Instruction: How did Ray JG, Deniz S, Olivieri A, et al. compare blood product use amongcoronary artery bypass patients?

Output: Increased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Ray JG, Deniz S, Olivieri A, et al. compare blood product use amongcoronary artery bypass patients?. ### Response: Increased.


Instruction: What is the effect of clopidogrel onperioperative blood loss and transfusion in coronary artery bypass graftsurgery?

Output: graft patency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of clopidogrel onperioperative blood loss and transfusion in coronary artery bypass graftsurgery?. ### Response: graft patency.


Instruction: What was the name of the study that investigated the effect on postoperative mortality and blood product requirements?

Output: Nippon Kyobu Geka Gakkai Zasshi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that investigated the effect on postoperative mortality and blood product requirements?. ### Response: Nippon Kyobu Geka Gakkai Zasshi.


Instruction: What are postoperativemorbidity and blood product requirements?

Output: artery bypass graft surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are postoperativemorbidity and blood product requirements?. ### Response: artery bypass graft surgery.


Instruction: What is the J Cardiothorac VascAnesth. 2008:22:60–6.1106?

Output: artery bypass graft surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Cardiothorac VascAnesth. 2008:22:60–6.1106?. ### Response: artery bypass graft surgery.


Instruction: How does preoperative aspirin and clopidogrel therapy affect perioperative blood loss and blood transfusion requirements in patients undergoing off-pump coronary artery bypassgraft surgery?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does preoperative aspirin and clopidogrel therapy affect perioperative blood loss and blood transfusion requirements in patients undergoing off-pump coronary artery bypassgraft surgery?. ### Response: Effects.


Instruction: What year did Cardiovasc Surg publish 134:59–64.1107?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Cardiovasc Surg publish 134:59–64.1107?. ### Response: 2007.


Instruction: What year was the ACC/AHA published?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the ACC/AHA published?. ### Response: 2002.


Instruction: Where does this guideline place T A73?

Output: QS21 and QS68 .

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does this guideline place T A73?. ### Response: QS21 and QS68 ..


Instruction: What is the basis of QS21 and QS68?

Output: T A73

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the basis of QS21 and QS68?. ### Response: T A73.


Instruction: Which guideline should be r ead in conjunction with NG185?

Output: T A73

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which guideline should be r ead in conjunction with NG185?. ### Response: T A73.


Instruction: What is the aim of the ECG?

Output: impr ove outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the aim of the ECG?. ### Response: impr ove outcomes.


Instruction: What is a multislice CT angiograph?

Output: high-sensitivity tr oponin t ests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a multislice CT angiograph?. ### Response: high-sensitivity tr oponin t ests.


Instruction: What is NICE's guideline on managing acute cor onar y syndromes?

Output: Healt hcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE's guideline on managing acute cor onar y syndromes?. ### Response: Healt hcare professionals.


Instruction: Who is i t for?

Output: Healt hcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is i t for?. ### Response: Healt hcare professionals.


Instruction: Adults wit h chest pain of r ecent onset, their families and carers What is the name of the assessment and diagnosis?

Output: CG95

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults wit h chest pain of r ecent onset, their families and carers What is the name of the assessment and diagnosis?. ### Response: CG95.


Instruction: What is CG95?

Output: assessment and diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CG95?. ### Response: assessment and diagnosis.


Instruction: What is NICE 2022?

Output: assessment and diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2022?. ### Response: assessment and diagnosis.


Instruction: Where is the Notice of right s?

Output: https://www .

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Notice of right s?. ### Response: https://www ..


Instruction: How many certification programs are available?

Output: 520

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many certification programs are available?. ### Response: 520.


Instruction: What may be insensitive to differentiating high-grade stenosis from complete occlusion?

Output: Duplex ultrasound

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be insensitive to differentiating high-grade stenosis from complete occlusion?. ### Response: Duplex ultrasound.


Instruction: What is the advantage of using MRA?

Output: providing images of both the cer -vical and intracranial portions of the carotid artery and its proximal intracranial branches

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the advantage of using MRA?. ### Response: providing images of both the cer -vical and intracranial portions of the carotid artery and its proximal intracranial branches.


Instruction: What may overestimate the degree of stenosis?

Output: MRA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may overestimate the degree of stenosis?. ### Response: MRA.


Instruction: What may occur when high-grade stenosis is differentiated from com-plete occlusion?

Output: errors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may occur when high-grade stenosis is differentiated from com-plete occlusion?. ### Response: errors.


Instruction: What may cause debilitating nephrogenic systemic fibrosis in patients with renal dysfunc-tion?

Output: MR contrast material

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may cause debilitating nephrogenic systemic fibrosis in patients with renal dysfunc-tion?. ### Response: MR contrast material.


Instruction: When concordant, the combination of duplex ultrasound and MRA is more accurate than what?

Output: either test alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When concordant, the combination of duplex ultrasound and MRA is more accurate than what?. ### Response: either test alone.


Instruction: What is another method of identifying and measuring stenosis of the extracranial carotid artery?

Output: Computed tomographic angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another method of identifying and measuring stenosis of the extracranial carotid artery?. ### Response: Computed tomographic angiography.


Instruction: Along with MRA, computed tomographic angiography has the advantage of being able to evaluate the intra-cranial circulation.

Output: 522

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Along with MRA, computed tomographic angiography has the advantage of being able to evaluate the intra-cranial circulation.. ### Response: 522.


Instruction: What may confound accurate measurement of stenosis with computed tomographic angiography?

Output: Atherosclerotic calcifi-cation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may confound accurate measurement of stenosis with computed tomographic angiography?. ### Response: Atherosclerotic calcifi-cation.


Instruction: A variety of vascular risk factors reviewed in this guideline are associated with what?

Output: carotid atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A variety of vascular risk factors reviewed in this guideline are associated with what?. ### Response: carotid atherosclerosis.


Instruction: Carotid bruit can reflect an underlying which?

Output: carotid stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Carotid bruit can reflect an underlying which?. ### Response: carotid stenosis.


Instruction: What is the sen-sitivity for detecting carotid stenosis low?

Output: Carotid bruit can reflect an underlying carotid stenosis. However, the sen-sitivity for detecting carotid stenosis is low. In NOMAS, aus-cultation had a sensitivity of 56% and a specificity of 98%.525

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sen-sitivity for detecting carotid stenosis low?. ### Response: Carotid bruit can reflect an underlying carotid stenosis. However, the sen-sitivity for detecting carotid stenosis is low. In NOMAS, aus-cultation had a sensitivity of 56% and a specificity of 98%.525.


Instruction: In NOMAS, aus-cultation had a sensitivity of what?

Output: 56%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In NOMAS, aus-cultation had a sensitivity of what?. ### Response: 56%.


Instruction: What was the first study with >1000 patients comparing CEA plus best medical therapy to medical therapy?

Output: Asymptomatic Carotid Atherosclerosis Study (ACAS).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the first study with >1000 patients comparing CEA plus best medical therapy to medical therapy?. ### Response: Asymptomatic Carotid Atherosclerosis Study (ACAS)..


Instruction: What was the primary outcome of the Asymptomatic Carotid Atherosclerosis Study?

Output: the composite of any stroke or death occurring in the perioperative period and ipsilateral cerebral infarction thereafter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome of the Asymptomatic Carotid Atherosclerosis Study?. ### Response: the composite of any stroke or death occurring in the perioperative period and ipsilateral cerebral infarction thereafter.


Instruction: How many patients did the Data and Safety Monitoring Committee randomize?

Output: 1662

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients did the Data and Safety Monitoring Committee randomize?. ### Response: 1662.


Instruction: What group called a halt to the trial because of a clear benefit in favor of CEA?

Output: Data and Safety Monitoring Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group called a halt to the trial because of a clear benefit in favor of CEA?. ### Response: Data and Safety Monitoring Committee.


Instruction: Patients randomized to surgery had contrast angiography showing diameter-reducing lesions of  60% using the North American method of measurement?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients randomized to surgery had contrast angiography showing diameter-reducing lesions of  60% using the North American method of measurement?. ### Response: ≥.


Instruction: What was considered the best medical man-agement?

Output: contrast angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered the best medical man-agement?. ### Response: contrast angiography.


Instruction: What was the overall risk over 5 years for ipsilateral stroke, any perioperative stroke and death?

Output: 5.1%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall risk over 5 years for ipsilateral stroke, any perioperative stroke and death?. ### Response: 5.1%.


Instruction: How much was the RR reduction for surgical patients?

Output: 53%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the RR reduction for surgical patients?. ### Response: 53%;.


Instruction: What was the RR reduction for CEA patients?

Output: 53%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR reduction for CEA patients?. ### Response: 53%;.


Instruction: How much was the 30-day stroke morbidity and all-cause mortality?

Output: 2.3%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the 30-day stroke morbidity and all-cause mortality?. ### Response: 2.3%,.