Instruction: How many pages were in the Nutr Rev. 2009 report?

Output: 67:114–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages were in the Nutr Rev. 2009 report?. ### Response: 67:114–.


Instruction: What is the name of the study that examined the relationship between physical activity and risk of coronary heart disease?

Output: meta-analy-sis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the relationship between physical activity and risk of coronary heart disease?. ### Response: meta-analy-sis.


Instruction: What are some of the lessons learned from epidemiological studies across age, gender, and race/nicity?

Output: Physical activity and cardiovascular health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the lessons learned from epidemiological studies across age, gender, and race/nicity?. ### Response: Physical activity and cardiovascular health.


Instruction: What is a meta-analysis of the relationship between physical activity and risk of coronary heart disease?

Output: Dose response

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of the relationship between physical activity and risk of coronary heart disease?. ### Response: Dose response.


Instruction: What is the acronym for Essential Process of Risk Assessment?

Output: S4.4.1.1-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Essential Process of Risk Assessment?. ### Response: S4.4.1.1-1.


Instruction: Where can you find ASCVD Risk Predictor Plus?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find ASCVD Risk Predictor Plus?. ### Response: http://tools.acc.org.


Instruction: When did you find S4.4.1.1-2?

Output: September 1, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did you find S4.4.1.1-2?. ### Response: September 1, 2018.


Instruction: What is the name of the ASCVD-Risk-Calculator?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ASCVD-Risk-Calculator?. ### Response: American Heart Association.


Instruction: Where can you find this information?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find this information?. ### Response: https://professional.heart.org/professional/GuidelinesStatements/ASCVDRiskCalculator/UCM_457698_ASCVD-Risk-Calculator.jsp.


Instruction: When was this information available?

Output: September 1, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this information available?. ### Response: September 1, 2018.


Instruction: What is a risk factor that can predict coronary heart disease?

Output: multivariable risk score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor that can predict coronary heart disease?. ### Response: multivariable risk score.


Instruction: What study predicts the 30-year risk of cardiovascular disease?

Output: Framingham Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study predicts the 30-year risk of cardiovascular disease?. ### Response: Framingham Heart Study.


Instruction: What is the Framingham Heart Study?

Output: Predicting the 30-year risk of cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Framingham Heart Study?. ### Response: Predicting the 30-year risk of cardiovascular disease.


Instruction: What is CT?

Output: computed tomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CT?. ### Response: computed tomography.


Instruction: What is DW-MRI?

Output: diffusion-weighted magnetic resonance imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DW-MRI?. ### Response: diffusion-weighted magnetic resonance imaging.


Instruction: FLAIR is fluid-attenuated inversion recovery.

Output: Table 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: FLAIR is fluid-attenuated inversion recovery.. ### Response: Table 8.


Instruction: What is the modified Rankin Scale?

Output: mRS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the modified Rankin Scale?. ### Response: mRS.


Instruction: What is NCCT?

Output: noncontrast computed tomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NCCT?. ### Response: noncontrast computed tomography.


Instruction: WHAT is the National Institutes of Health Stroke Scale called?

Output: NIHSS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: WHAT is the National Institutes of Health Stroke Scale called?. ### Response: NIHSS.


Instruction: What was considered the time when the patient was last known to be normal or at baseline neurological condition?

Output: the time of onset time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered the time when the patient was last known to be normal or at baseline neurological condition?. ### Response: the time of onset time.


Instruction: What was the recommendation unchanged or reworded for clarity from 2015 IV Alteplase?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the recommendation unchanged or reworded for clarity from 2015 IV Alteplase?. ### Response: †.


Instruction: What is the maximum dose of AlteplaseInfuse?

Output: 90 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum dose of AlteplaseInfuse?. ### Response: 90 mg.


Instruction: What is the maximum dose of Alteplase?

Output: 90 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum dose of Alteplase?. ### Response: 90 mg.


Instruction: How much of the dose is given as a bolus over 1 min?

Output: 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the dose is given as a bolus over 1 min?. ### Response: 10%.


Instruction: What type of unit is used for monitoring if the patient develops severe headache, hypertension, nausea or vomiting?

Output: intensive care or stroke unit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of unit is used for monitoring if the patient develops severe headache, hypertension, nausea or vomiting?. ### Response: intensive care or stroke unit.


Instruction: What should you do if you have severe headache, acute hypertension, nausea, or vomiting?

Output: discontinue the infusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should you do if you have severe headache, acute hypertension, nausea, or vomiting?. ### Response: discontinue the infusion.


Instruction: If you have a worsening neurological examination, discontinue the IV alteplase infusion and obtain an emergency head CT scan?

Output: infusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If you have a worsening neurological examination, discontinue the IV alteplase infusion and obtain an emergency head CT scan?. ### Response: infusion.


Instruction: How long is alteplase infusion?

Output: 2 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is alteplase infusion?. ### Response: 2 h.


Instruction: How many h is altplasa infusion every 30 min for 6 h?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many h is altplasa infusion every 30 min for 6 h?. ### Response: 2.


Instruction: What is the frequency of BP measurements if SBP is >180 mm Hg?

Output: Increase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the frequency of BP measurements if SBP is >180 mm Hg?. ### Response: Increase.


Instruction: Antihypertensive medications to maintain BP at or below what levels?

Output: SBP is >180 mm Hg or if DBP is >105 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antihypertensive medications to maintain BP at or below what levels?. ### Response: SBP is >180 mm Hg or if DBP is >105 mm Hg.


Instruction: Delay placement of nasogastric tubes, indwelling bladder catheters or intra-arterial pressure catheters if the patient can be safely managed without them.

Output: bladder catheters

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Delay placement of nasogastric tubes, indwelling bladder catheters or intra-arterial pressure catheters if the patient can be safely managed without them.. ### Response: bladder catheters.


Instruction: How long after IV alteplase before starting anticoagulants or antiplatelet agents?

Output: 24 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after IV alteplase before starting anticoagulants or antiplatelet agents?. ### Response: 24 h.


Instruction: AIS indicates acute ischemic stroke.

Output: bladder catheters

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AIS indicates acute ischemic stroke.. ### Response: bladder catheters.


Instruction: CT, computed tomography, DBP, diastolic blood pressure.

Output: bladder catheters

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CT, computed tomography, DBP, diastolic blood pressure.. ### Response: bladder catheters.


Instruction: IV, intravenous, magnetic resonance imaging, and what else?

Output: MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: IV, intravenous, magnetic resonance imaging, and what else?. ### Response: MRI.


Instruction: What year was the 2013 American Heart Association, Inc.Downloaded from http://ahajournals.org by on April 28, 2023?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the 2013 American Heart Association, Inc.Downloaded from http://ahajournals.org by on April 28, 2023?. ### Response: 2013.


Instruction: What is the name of the study that investigated immediate coronary angiography in survivors of out-of-hospital cardiac arrest?

Output: N Engl J Med.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated immediate coronary angiography in survivors of out-of-hospital cardiac arrest?. ### Response: N Engl J Med..


Instruction: What is a modern therapeutic approach to post-resuscitation care?

Output: Treatment and outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a modern therapeutic approach to post-resuscitation care?. ### Response: Treatment and outcome.


Instruction: When was the N Engl J Med 336:1629–33.174?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 336:1629–33.174?. ### Response: 1997.


Instruction: What was introduced to post-resuscitation care after out-of-hospital cardiac arrest?

Output: modern therapeutic approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was introduced to post-resuscitation care after out-of-hospital cardiac arrest?. ### Response: modern therapeutic approach.


Instruction: Resuscitation. 2007;73:40–5.175.

Output: Treatment and outcome in post-resuscitation care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Resuscitation. 2007;73:40–5.175.. ### Response: Treatment and outcome in post-resuscitation care.


Instruction: What did the American Heart Association report on in 2010?

Output: Heart disease and stroke statistics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American Heart Association report on in 2010?. ### Response: Heart disease and stroke statistics.


Instruction: What is the current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review?

Output: in a large U.S. community

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review?. ### Response: in a large U.S. community.


Instruction: What is a regional variation in out-of-hospital cardiac arrest incidence and outcome?

Output: JAMA. 2008;300:1423–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a regional variation in out-of-hospital cardiac arrest incidence and outcome?. ### Response: JAMA. 2008;300:1423–.


Instruction: What is the difference between multiple source surveillance and retrospective death certificate-based review in a large U.S. community?

Output: Current burden of sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between multiple source surveillance and retrospective death certificate-based review in a large U.S. community?. ### Response: Current burden of sudden cardiac death.


Instruction: When was the J Am Coll Cardiol 44:1268–75.178?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 44:1268–75.178?. ### Response: 2004.


Instruction: What model was used to estimate the effectiveness of cardi-ac arrest interventions?

Output: logistic regression survival model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What model was used to estimate the effectiveness of cardi-ac arrest interventions?. ### Response: logistic regression survival model.


Instruction: What is the "chain of survival" concept?

Output: a statement for health professionals from the Advanced Cardiac Life Support Subcommittee and the Emergency Cardiac Care Committee, American Heart Associa-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the "chain of survival" concept?. ### Response: a statement for health professionals from the Advanced Cardiac Life Support Subcommittee and the Emergency Cardiac Care Committee, American Heart Associa-tion.


Instruction: What is a statement for health professionals from the Advanced Cardiac Life Support Subcommittee?

Output: the “chain of survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a statement for health professionals from the Advanced Cardiac Life Support Subcommittee?. ### Response: the “chain of survival.


Instruction: When did Circulation. 1991;83:1832–47.180?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 1991;83:1832–47.180?. ### Response: 1997.


Instruction: What is a graphic model for predicting survival from out-of-hospital cardiac arrest?

Output: Immediate coronary an-giography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a graphic model for predicting survival from out-of-hospital cardiac arrest?. ### Response: Immediate coronary an-giography.


Instruction: What is an evaluation in the Resuscitation department?

Output: Law Enforcement Agency Defibrillation (LEA-D): proceedings of the National Center for Early Defibrillation Police AED Issues Forum

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an evaluation in the Resuscitation department?. ### Response: Law Enforcement Agency Defibrillation (LEA-D): proceedings of the National Center for Early Defibrillation Police AED Issues Forum.


Instruction: What is the population of the Resuscitation Outcomes Consortium?

Output: 21 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population of the Resuscitation Outcomes Consortium?. ### Response: 21 million.


Instruction: How many years of experience with early defibrillation by police and paramedics in an emergency medical services system?

Output: Seven

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of experience with early defibrillation by police and paramedics in an emergency medical services system?. ### Response: Seven.


Instruction: What is the acronym for Law Enforcement Agency Defibrillation?

Output: LEA-D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Law Enforcement Agency Defibrillation?. ### Response: LEA-D.


Instruction: What does LEA-D stand for?

Output: Law Enforcement Agency Defibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LEA-D stand for?. ### Response: Law Enforcement Agency Defibrillation.


Instruction: What did the National Center for Early Defibrillation Police AED Issues Forum focus on?

Output: Law Enforcement Agency Defibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the National Center for Early Defibrillation Police AED Issues Forum focus on?. ### Response: Law Enforcement Agency Defibrillation.


Instruction: What did Groh WJ, Lowe MR, Overgaard AD, et al. Attitudes of law enforcement officers regarding?

Output: automated external defibrillators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Groh WJ, Lowe MR, Overgaard AD, et al. Attitudes of law enforcement officers regarding?. ### Response: automated external defibrillators.


Instruction: What is a key link in the chain of sur-vival?

Output: Automatic external defibrillator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key link in the chain of sur-vival?. ### Response: Automatic external defibrillator.


Instruction: What is the impact of community-wide police car deployment of automated external defibrillators on?

Output: survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of community-wide police car deployment of automated external defibrillators on?. ### Response: survival.


Instruction: What is posaconazole?

Output: itraconazole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is posaconazole?. ### Response: itraconazole.


Instruction: What is ranolazine?

Output: posaconazole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ranolazine?. ### Response: posaconazole.


Instruction: On what date was this page accessed?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was this page accessed?. ### Response: April 23, 2023.


Instruction: What should clinicians add to maximally tolerated statin therapy as a first step in lowering LDL-C further?

Output: ezetimibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should clinicians add to maximally tolerated statin therapy as a first step in lowering LDL-C further?. ### Response: ezetimibe.


Instruction: No RCT specifically tested the strategy of what?

Output: ezetimibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No RCT specifically tested the strategy of what?. ### Response: ezetimibe.


Instruction: ezetimibe was allowed at entry along with what other drug?

Output: statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ezetimibe was allowed at entry along with what other drug?. ### Response: statin therapy.


Instruction: What percentage of patients were on ezetimibe during these trials?

Output: 3% and 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients were on ezetimibe during these trials?. ### Response: 3% and 5%.


Instruction: What is the strategy of ezetimibe before PCSK9 inhibitor recommended?

Output: addition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strategy of ezetimibe before PCSK9 inhibitor recommended?. ### Response: addition.


Instruction: What is widely avail-able as a generic drug and has proven safety and tolerability?

Output: ezetimibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is widely avail-able as a generic drug and has proven safety and tolerability?. ### Response: ezetimibe.


Instruction: How many simulation studies supported this approach?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many simulation studies supported this approach?. ### Response: 2.


Instruction: What does ezetimibe do to lower LDL-C in the majority of patients?

Output: <70 mg/dL (1.8 mmol/L)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ezetimibe do to lower LDL-C in the majority of patients?. ### Response: <70 mg/dL (1.8 mmol/L).


Instruction: What percentage of patients are eligible for a PCSK9 inhibitor?

Output: minority

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients are eligible for a PCSK9 inhibitor?. ### Response: minority.


Instruction: What is the LOE of ezetimibe before PCSK9 inhibitor?

Output: B-NR.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LOE of ezetimibe before PCSK9 inhibitor?. ### Response: B-NR.4.


Instruction: What did the FOURIER trial evaluate among patients with ASCVD who met at least 1 major or 2 minor criteria?

Output: evolocumab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the FOURIER trial evaluate among patients with ASCVD who met at least 1 major or 2 minor criteria?. ### Response: evolocumab.


Instruction: Who met at least 1 major or 2 minor criteria for ASCVD?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who met at least 1 major or 2 minor criteria for ASCVD?. ### Response: patients.


Instruction: Who was recruited to patients who had LDL-C 70 mg/dL?

Output: minority

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was recruited to patients who had LDL-C 70 mg/dL?. ### Response: minority.


Instruction: What was the median follow-up of 2.2 years for evolocumab?

Output: significantly reduced composite ASC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median follow-up of 2.2 years for evolocumab?. ### Response: significantly reduced composite ASC.


Instruction: What did evolocumab significantly reduce?

Output: composite ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did evolocumab significantly reduce?. ### Response: composite ASCVD.


Instruction: What was the median age of patients on alirocumab with ACS in the ODYSSEY OUTCOMES trial?

Output: 2.8 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median age of patients on alirocumab with ACS in the ODYSSEY OUTCOMES trial?. ### Response: 2.8 years.


Instruction: What was the median age of ezetimibe with ACS?

Output: 2.8 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median age of ezetimibe with ACS?. ### Response: 2.8 years.


Instruction: What percentage of RRR was observed in patients with clinical ASCVD?

Output: 15%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of RRR was observed in patients with clinical ASCVD?. ### Response: 15%.


Instruction: Which color corresponds to Class of Recommendation in Table 2?

Output: B-NR.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which color corresponds to Class of Recommendation in Table 2?. ### Response: B-NR.4.


Instruction: What is TIA?

Output: transient ischemic attack

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TIA?. ### Response: transient ischemic attack.


Instruction: What is PAD?

Output: peripheral artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PAD?. ### Response: peripheral artery disease.


Instruction: How many major ASCVD events does very high-risk include?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many major ASCVD events does very high-risk include?. ### Response: 1.


Instruction: How many major ASCVD events are there?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many major ASCVD events are there?. ### Response: 1.


Instruction: How many high-risk conditions are there in the United States?

Output: multiple

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many high-risk conditions are there in the United States?. ### Response: multiple.


Instruction: What is the acronym for atherosclerotic cardiovascular disease?

Output: ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for atherosclerotic cardiovascular disease?. ### Response: ASCVD.


Instruction: What did Shin IS, Park MS, Cho KH, et al. Comparative validity of depression assessment scales for screening poststroke depression?

Output: 2013;147:186–191

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Shin IS, Park MS, Cho KH, et al. Comparative validity of depression assessment scales for screening poststroke depression?. ### Response: 2013;147:186–191.


Instruction: What did J Affect Disord. 2013;147:186–191. doi: 10.1016/j.jad.2012.10.035 273.

Output: Comparative validity of depression assessment scales for screening poststroke depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did J Affect Disord. 2013;147:186–191. doi: 10.1016/j.jad.2012.10.035 273.. ### Response: Comparative validity of depression assessment scales for screening poststroke depression.


Instruction: What was a randomized, controlled trial?

Output: Care management of poststroke depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a randomized, controlled trial?. ### Response: Care management of poststroke depression.


Instruction: What is the name of the randomized, controlled trial of management of poststroke depression?

Output: The Preventive Antibiotics in Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, controlled trial of management of poststroke depression?. ### Response: The Preventive Antibiotics in Stroke Study.


Instruction: How many people were involved in the PASS study?

Output: 61 274

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were involved in the PASS study?. ### Response: 61 274.


Instruction: What is PASS?

Output: The Preventive Antibiotics in Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PASS?. ### Response: The Preventive Antibiotics in Stroke Study.


Instruction: Antibiotics in Stroke Study: a pragmatic randomised open-label masked endpoint clinical trial.

Output: PASS investigators. The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial. Lancet. 2015;385:1519–1526. doi: 10.1016/S0140-6736(14)62456-9 275

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antibiotics in Stroke Study: a pragmatic randomised open-label masked endpoint clinical trial.. ### Response: PASS investigators. The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial. Lancet. 2015;385:1519–1526. doi: 10.1016/S0140-6736(14)62456-9 275.


Instruction: What does STROKE-INF do?

Output: Prophylactic anti-biotics after acute stroke for reducing pneumonia in patients with dys-phagia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does STROKE-INF do?. ### Response: Prophylactic anti-biotics after acute stroke for reducing pneumonia in patients with dys-phagia.


Instruction: What is the name of the prospective, cluster-randomised, open-label, masked endpoint, controlled clinical trial of stroke for reducing pneumonia in patients with dys-phagia?

Output: STROKE-INF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective, cluster-randomised, open-label, masked endpoint, controlled clinical trial of stroke for reducing pneumonia in patients with dys-phagia?. ### Response: STROKE-INF.


Instruction: When was the trial downloaded from http://ahajournals.org by?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the trial downloaded from http://ahajournals.org by?. ### Response: April 28, 2023.


Instruction: How many Stroke were there in May 2014?

Output: 1552

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Stroke were there in May 2014?. ### Response: 1552.


Instruction: What increases the risk for preeclamp-sia and stroke during pregnancy?

Output: Hypertension in Women of Childbearing AgePrepregnancy hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the risk for preeclamp-sia and stroke during pregnancy?. ### Response: Hypertension in Women of Childbearing AgePrepregnancy hypertension.


Instruction: The choice of BP-lowering medications before pregnancy should be made based on what?

Output: a woman’s intentions for future pregnancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The choice of BP-lowering medications before pregnancy should be made based on what?. ### Response: a woman’s intentions for future pregnancy.


Instruction: What are some medications associated with if they are continued during pregnancy?

Output: various risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some medications associated with if they are continued during pregnancy?. ### Response: various risks.


Instruction: What have been used in pregnancy; all transfer across the placenta?

Output: 120a,121*α-Blockers, β-blockers, CCBs, hydralazine, and thiazide diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have been used in pregnancy; all transfer across the placenta?. ### Response: 120a,121*α-Blockers, β-blockers, CCBs, hydralazine, and thiazide diuretics.


Instruction: There are no data from large, well-controlled, random-ized controlled trials directly comparing specific antihypertensive agents in pregnancy.

Output: Methyldopa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are no data from large, well-controlled, random-ized controlled trials directly comparing specific antihypertensive agents in pregnancy.. ### Response: Methyldopa.


Instruction: What has been extensively used in pregnancy and appears to be safe?

Output: Methyldopa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been extensively used in pregnancy and appears to be safe?. ### Response: Methyldopa.


Instruction: What did a Cochrane review of the use of -blockers in pregnancy note?

Output: decreased the risk of progression to severe hypertension but may have increased risk for fetal growth restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a Cochrane review of the use of -blockers in pregnancy note?. ### Response: decreased the risk of progression to severe hypertension but may have increased risk for fetal growth restriction.


Instruction: What may have increased the risk of fetal growth restriction?

Output: β-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have increased the risk of fetal growth restriction?. ### Response: β-blockers.


Instruction: Why is atenolol not recom-mend in pregnancy?

Output: its known association with fetal growth restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is atenolol not recom-mend in pregnancy?. ### Response: its known association with fetal growth restriction.


Instruction: Atenolol is not recom-mend in pregnancy because of its association with what?

Output: fetal growth restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atenolol is not recom-mend in pregnancy because of its association with what?. ### Response: fetal growth restriction.


Instruction: Pindol and metoprolol appear safe for use in pregnancy.

Output: Methyldopa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pindol and metoprolol appear safe for use in pregnancy.. ### Response: Methyldopa.


Instruction: What is the most commonly used CCB in pregnancy?

Output: nifedipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most commonly used CCB in pregnancy?. ### Response: nifedipine.


Instruction: What is nifedipine?

Output: CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is nifedipine?. ### Response: CCB.


Instruction: What was a 2007 Cochrane review of the risk for preeclampsia with the use of CCBs versus no ther -apy?

Output: small increase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a 2007 Cochrane review of the risk for preeclampsia with the use of CCBs versus no ther -apy?. ### Response: small increase.


Instruction: Diuretics, predominantly thiazide-type, have been indicated to be what in pregnancy?

Output: safe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diuretics, predominantly thiazide-type, have been indicated to be what in pregnancy?. ### Response: safe.


Instruction: What did a 2007 Cochrane review examine the use of to prevent preeclampsia?

Output: diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a 2007 Cochrane review examine the use of to prevent preeclampsia?. ### Response: diuretics.


Instruction: What did the reviewers note that several studies were of uncertain quality?

Output: thiazides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the reviewers note that several studies were of uncertain quality?. ### Response: thiazides.


Instruction: How many trials were there?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many trials were there?. ### Response: 4.


Instruction: How many women were in the trials?

Output: 1391

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many women were in the trials?. ### Response: 1391.


Instruction: What was the RR of the trial?

Output: 0.68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of the trial?. ### Response: 0.68.


Instruction: Why are angio-tensin receptor blockers and renin inhibitors contraindicated?

Output: teratoge-nicity and adverse fetal outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are angio-tensin receptor blockers and renin inhibitors contraindicated?. ### Response: teratoge-nicity and adverse fetal outcomes.


Instruction: Why is there insufficient evidence to warrant a different approach to BP treatment in women from that used for men?

Output: the existing guidelines for measurement, identification, and man-agement of BP in adults should be followed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there insufficient evidence to warrant a different approach to BP treatment in women from that used for men?. ### Response: the existing guidelines for measurement, identification, and man-agement of BP in adults should be followed.


Instruction: What are the existing guidelines for measurement, identification, and man-agement of BP in adults?

Output: should be followed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the existing guidelines for measurement, identification, and man-agement of BP in adults?. ### Response: should be followed.


Instruction: What should be followed for measurement, identification, and man-agement of BP in adults?

Output: existing guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be followed for measurement, identification, and man-agement of BP in adults?. ### Response: existing guidelines.


Instruction: Existing guide-lines for nonpharmacological intervention (predominantly dietary modification) to lower BP and to reduce stroke risk should what be followed?

Output: the existing guidelines for measurement, identification, and man-agement of BP in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Existing guide-lines for nonpharmacological intervention (predominantly dietary modification) to lower BP and to reduce stroke risk should what be followed?. ### Response: the existing guidelines for measurement, identification, and man-agement of BP in adults.


Instruction: What is unclear whether the age-related decline in BP control among women is related to?

Output: inad-equate intensity of treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unclear whether the age-related decline in BP control among women is related to?. ### Response: inad-equate intensity of treatment.


Instruction: What is the cause of the decline in BP control among women?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of the decline in BP control among women?. ### Response: age.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 12 of 134 The grade of each recommendation can be found in the section on Recommendations?

Output: VA/DoD HTN CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 12 of 134 The grade of each recommendation can be found in the section on Recommendations?. ### Response: VA/DoD HTN CPG.


Instruction: Where can additional information regarding the GRADE system be found?

Output: Appendix A. b

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can additional information regarding the GRADE system be found?. ### Response: Appendix A. b.


Instruction: Evidence based CPGs should be what?

Output: current

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence based CPGs should be what?. ### Response: current.


Instruction: What typically requires revisions of previous guidelines?

Output: Evidence -based CPGs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What typically requires revisions of previous guidelines?. ### Response: Evidence -based CPGs.


Instruction: What does USPSTF stand for?

Output: U.S. Preventive Services Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does USPSTF stand for?. ### Response: U.S. Preventive Services Task Force.


Instruction: What is the focus of the HTN CPG Work Group?

Output: developing new and updated recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the HTN CPG Work Group?. ### Response: developing new and updated recommendations.


Instruction: What was the focus of the HTN CPG Work Group?

Output: developing new and updated recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the HTN CPG Work Group?. ### Response: developing new and updated recommendations.


Instruction: What did the Work Group consider without complete review of the relevant evidence?

Output: the current applicability of other recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group consider without complete review of the relevant evidence?. ### Response: the current applicability of other recommendations.


Instruction: What did the 2014 VA/DoD HTN CPG consider without complete review of the relevant evidence?

Output: current applicability of other recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2014 VA/DoD HTN CPG consider without complete review of the relevant evidence?. ### Response: current applicability of other recommendations.


Instruction: A set of recommendation categories was adapted from those used by what organization?

Output: National Institute for Health and Care Excellence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A set of recommendation categories was adapted from those used by what organization?. ### Response: National Institute for Health and Care Excellence.


Instruction: Who used the categories used by NICE?

Output: National Institute for Health and Care Excellence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who used the categories used by NICE?. ### Response: National Institute for Health and Care Excellence.


Instruction: What did the categories account for?

Output: various ways in which older recommendations could have been updated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the categories account for?. ### Response: various ways in which older recommendations could have been updated.


Instruction: How was evidence related to a recommendation systematically reviewed?

Output: modified

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was evidence related to a recommendation systematically reviewed?. ### Response: modified.


Instruction: How was the recommendation modified?

Output: based on new evidence or as scheduled and subject to time -based expirations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the recommendation modified?. ### Response: based on new evidence or as scheduled and subject to time -based expirations.


Instruction: What is relevant in the current care environment and within the scope of the CPG?

Output: a recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is relevant in the current care environment and within the scope of the CPG?. ### Response: a recommendation.


Instruction: What are the categories for recommendations included in the 2020 version of the guideline?

Output: section on Recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the categories for recommendations included in the 2020 version of the guideline?. ### Response: section on Recommendations.


Instruction: Where can additional information regarding the categories and their definitions be found?

Output: Recommendation Categorization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can additional information regarding the categories and their definitions be found?. ### Response: Recommendation Categorization.


Instruction: What are the categories for the recommendations carried forward from the 2014 VA/DoD HTN CPG noted in?

Output: Appendix D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the categories for the recommendations carried forward from the 2014 VA/DoD HTN CPG noted in?. ### Response: Appendix D.


Instruction: What was the iterative process in which the Work Group produced multiple drafts of the CPG?

Output: Peer Review Process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the iterative process in which the Work Group produced multiple drafts of the CPG?. ### Response: Peer Review Process.


Instruction: The process for developing the initial draft was what?

Output: Drafting and Submitting the Final Clinical Practice Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The process for developing the initial draft was what?. ### Response: Drafting and Submitting the Final Clinical Practice Guideline.


Instruction: What is the process for developing the initial draft of the CPG described in more detail in Drafting and Submitting the Final Clinical Practice Guideline?

Output: iterative process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the process for developing the initial draft of the CPG described in more detail in Drafting and Submitting the Final Clinical Practice Guideline?. ### Response: iterative process.


Instruction: How long did it take for the draft to be posted on a wiki website?

Output: 14 business days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for the draft to be posted on a wiki website?. ### Response: 14 business days.


Instruction: Who were the peer reviewers?

Output: ind ividuals working within the VA and DoD healthcare systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were the peer reviewers?. ### Response: ind ividuals working within the VA and DoD healthcare systems.


Instruction: What should prompt a focused investigation for possible association with VA?

Output: symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should prompt a focused investigation for possible association with VA?. ### Response: symptoms.


Instruction: What are some precipitating factors?

Output: Exercise, emotional stress

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some precipitating factors?. ### Response: Exercise, emotional stress.


Instruction: What is an important factor in the development of SCD?

Output: elucidation of precipitating factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important factor in the development of SCD?. ### Response: elucidation of precipitating factors.


Instruction: What is a risk factor for SCD, ischemic heart disease or HF?

Output: family history

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for SCD, ischemic heart disease or HF?. ### Response: family history.


Instruction: What is the name of a website that can help you determine if you have a VA disorder?

Output: crediblemeds.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a website that can help you determine if you have a VA disorder?. ### Response: crediblemeds.org.


Instruction: What are some medications that can cause QT prolongation and torsades de pointes?

Output: Antiarrhythmic medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some medications that can cause QT prolongation and torsades de pointes?. ### Response: Antiarrhythmic medications.


Instruction: I electrocardiographic pat-tern and VF (www.brugadadrugs.org)?

Output: Brugada

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: I electrocardiographic pat-tern and VF (www.brugadadrugs.org)?. ### Response: Brugada.


Instruction: Patients with bigeminy and trigeminy can present with what?

Output: effective bradycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with bigeminy and trigeminy can present with what?. ### Response: effective bradycardia.


Instruction: Effective bradycardia, an apical-radial pulse deficit and relative hypertension with a wide pulse pressure are symptoms of what condition?

Output: bigeminy and trigeminy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Effective bradycardia, an apical-radial pulse deficit and relative hypertension with a wide pulse pressure are symptoms of what condition?. ### Response: bigeminy and trigeminy.


Instruction: What can be detected on auscultation of the heart?

Output: premature beats

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be detected on auscultation of the heart?. ### Response: premature beats.


Instruction: What is the focus of the physi-cal examination?

Output: finding evidence of structural heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the physi-cal examination?. ### Response: finding evidence of structural heart disease.


Instruction: Carotid bruits or diminished peripheral pulses are indicators of what?

Output: structural heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Carotid bruits or diminished peripheral pulses are indicators of what?. ### Response: structural heart disease.


Instruction: Jugular venous distention, rales, gallops, and peripheral edema provide evidence of what?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Jugular venous distention, rales, gallops, and peripheral edema provide evidence of what?. ### Response: HF.


Instruction: Auscultation may reveal cardiac murmurs consistent with what type of heart disease?

Output: valvular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Auscultation may reveal cardiac murmurs consistent with what type of heart disease?. ### Response: valvular.


Instruction: A midsystolic click may indi-cate what kind of valve prolapse?

Output: mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A midsystolic click may indi-cate what kind of valve prolapse?. ### Response: mitral.


Instruction: What may indi-cate mitral valve prolapse that can be associated with VA?

Output: A midsystolic click

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may indi-cate mitral valve prolapse that can be associated with VA?. ### Response: A midsystolic click.


Instruction: What are many VA that are asymptomatic and detected only on an ECG or telemetry?

Output: S4.1-11–S4.1-13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are many VA that are asymptomatic and detected only on an ECG or telemetry?. ### Response: S4.1-11–S4.1-13.


Instruction: What may result in syncope sec-ondary to marked reduction in cardiac output?

Output: Rapid, sustained VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may result in syncope sec-ondary to marked reduction in cardiac output?. ### Response: Rapid, sustained VT.


Instruction: Important Considerations in the Evaluation of Patients With Known or Suspected VAComponentAssessment and Findings Relevant for VA and/or SCD RiskHistory What are symptoms/events related to arrhythmia?

Output: Palpitations, lightheadedness, syncope, dyspnea, chest pain, cardiac arrest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Important Considerations in the Evaluation of Patients With Known or Suspected VAComponentAssessment and Findings Relevant for VA and/or SCD RiskHistory What are symptoms/events related to arrhythmia?. ### Response: Palpitations, lightheadedness, syncope, dyspnea, chest pain, cardiac arrest.


Instruction: What is a known heart disease?

Output: Coronary, valvular (eg, mitral valve prolapse), congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a known heart disease?. ### Response: Coronary, valvular (eg, mitral valve prolapse), congenital heart disease.


Instruction: What is an underlying heart disease symptom?

Output: Dys

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an underlying heart disease symptom?. ### Response: Dys.


Instruction: What is a risk factor for heart disease?

Output: Hypertension, diabetes mellitus, hyperlipidemia, and smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for heart disease?. ### Response: Hypertension, diabetes mellitus, hyperlipidemia, and smoking.


Instruction: What are other medications with potential for QT?

Output: Antiarrhythmic medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are other medications with potential for QT?. ### Response: Antiarrhythmic medications.


Instruction: What is rapher in the era of the functional aortic annulus?

Output: Chronic aortic insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rapher in the era of the functional aortic annulus?. ### Response: Chronic aortic insufficiency.


Instruction: What is Trost JC, Hillis LD?

Output: Intra-aortic balloon counterpulsation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Trost JC, Hillis LD?. ### Response: Intra-aortic balloon counterpulsation.


Instruction: How is chronic AR4.3.1 diagnosed?

Output: 1. Zoghbi WA, Adams D, Bonow RO, et al. Recommendations for noninva-sive evaluation of native valvular regurgitation: a report from the Ameri-can Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is chronic AR4.3.1 diagnosed?. ### Response: 1. Zoghbi WA, Adams D, Bonow RO, et al. Recommendations for noninva-sive evaluation of native valvular regurgitation: a report from the Ameri-can Society of Echocardiography.


Instruction: What does the American Society of Echocardiography recommend for noninvasive evaluation of native valvular regurgitation?

Output: Recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American Society of Echocardiography recommend for noninvasive evaluation of native valvular regurgitation?. ### Response: Recommendations.


Instruction: What was developed in collaboration with the Society for Cardiovascular Magnetic Resonance?

Output: i-can Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed in collaboration with the Society for Cardiovascular Magnetic Resonance?. ### Response: i-can Society of Echocardiography.


Instruction: When did J Am Soc Echocardiogr. 2017;30:303–71?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Soc Echocardiogr. 2017;30:303–71?. ### Response: 2017.


Instruction: What is a determinant of clinical outcome in asymptomatic patients with aortic regurgitation?

Output: Quantitative echocar -diographic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a determinant of clinical outcome in asymptomatic patients with aortic regurgitation?. ### Response: Quantitative echocar -diographic.


Instruction: What is the JACC Cardiovasc Imaging. 2008;1:1-11?

Output: Quantitative echocar -diographic determinants of clinical outcome in asymptomatic patients with aortic regurgitation: a prospective study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JACC Cardiovasc Imaging. 2008;1:1-11?. ### Response: Quantitative echocar -diographic determinants of clinical outcome in asymptomatic patients with aortic regurgitation: a prospective study.


Instruction: Pizarro R, Bazzino OO, Oberti PF, et al. Prospective validation of the prognostic usefulness of what?

Output: B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pizarro R, Bazzino OO, Oberti PF, et al. Prospective validation of the prognostic usefulness of what?. ### Response: B-type natriuretic peptide.


Instruction: In what year did Bonow RO, Picone AL, McIntosh CL, et al. perform a valve replacement for aortic regurgitation?

Output: 1976

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Bonow RO, Picone AL, McIntosh CL, et al. perform a valve replacement for aortic regurgitation?. ### Response: 1976.


Instruction: What was the im-pact of preoperative left ventricular function?

Output: Survival and functional results after valve replacement for aortic regurgitation from 1976 to 1983

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the im-pact of preoperative left ventricular function?. ### Response: Survival and functional results after valve replacement for aortic regurgitation from 1976 to 1983.


Instruction: What is a predictor of surgical results in chronic aortic insufficiency?

Output: Preoperative M-mode echocardiog-raphy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of surgical results in chronic aortic insufficiency?. ### Response: Preoperative M-mode echocardiog-raphy.


Instruction: What is the role of preoperative M-mode echocardiog-raphy?

Output: a predictor of surgical results in chronic aortic insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of preoperative M-mode echocardiog-raphy?. ### Response: a predictor of surgical results in chronic aortic insufficiency.


Instruction: When was J Thorac Cardiovasc Surg published?

Output: 1980

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was J Thorac Cardiovasc Surg published?. ### Response: 1980.


Instruction: What is the name of the serial long-term assessment of the natural history of asymptomatic patients with chronic aortic regurgitation and normal left ventricular systolic function?

Output: Bonow RO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the serial long-term assessment of the natural history of asymptomatic patients with chronic aortic regurgitation and normal left ventricular systolic function?. ### Response: Bonow RO.


Instruction: When did Circulation. 1991;84:1625-35?

Output: 1985

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 1991;84:1625-35?. ### Response: 1985.


Instruction: What is Bonow RO, Rosing DR, McIntosh CL, et al.?

Output: The natural history of asymp-tomatic patients with aortic regurgitation and normal left ventricular func-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Bonow RO, Rosing DR, McIntosh CL, et al.?. ### Response: The natural history of asymp-tomatic patients with aortic regurgitation and normal left ventricular func-tion.


Instruction: What is the name of the journal that studies valve replacement in patients with chronic aortic regurgitation and normal left ventricular performance?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies valve replacement in patients with chronic aortic regurgitation and normal left ventricular performance?. ### Response: Circulation.


Instruction: What are the names of the journals that study valve replacement?

Output: Borer JS, Hochreiter C, Herrold EM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the journals that study valve replacement?. ### Response: Borer JS, Hochreiter C, Herrold EM.


Instruction: How many patients with asymptomatic or minimally symptomatic conditions have valve replacements?

Output: 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with asymptomatic or minimally symptomatic conditions have valve replacements?. ### Response: 8.


Instruction: What is the name of the study that investigated the relationship between natural history and left ventricular re-sponse in chronic aortic regurgitation?

Output: Ishii K, Hirota Y, Suwa M, et al. Natural history and left ventricular re-sponse in chronic aortic regurgitation. Am J Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the relationship between natural history and left ventricular re-sponse in chronic aortic regurgitation?. ### Response: Ishii K, Hirota Y, Suwa M, et al. Natural history and left ventricular re-sponse in chronic aortic regurgitation. Am J Cardiol.


Instruction: What year was the Am J Cardiol 78:357–61 published?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the Am J Cardiol 78:357–61 published?. ### Response: 1996.


Instruction: Who is the author of the paper that examined the association between myocardial dysfunc-tion and asymptomatic patients?

Output: Scognamiglio R

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the paper that examined the association between myocardial dysfunc-tion and asymptomatic patients?. ### Response: Scognamiglio R.


Instruction: How did Scognamiglio R, Rahimtoola SH, Fasoli G, Dalla Volta S develop?

Output: in collaboration with the Society for Cardiovascular Magnetic Resonance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Scognamiglio R, Rahimtoola SH, Fasoli G, Dalla Volta S develop?. ### Response: in collaboration with the Society for Cardiovascular Magnetic Resonance.


Instruction: Insufficiency. Clin Cardiol. 1986;9:151–6. 11. Scognamiglio R, Rahimtoola SH, Fasoli G, et al. Nifedipine in asymptomatic patients with severe aortic regurgitation and normal left ventricular function. N Engl J Med. 1994;331:689–94.

Output: aortic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Insufficiency. Clin Cardiol. 1986;9:151–6. 11. Scognamiglio R, Rahimtoola SH, Fasoli G, et al. Nifedipine in asymptomatic patients with severe aortic regurgitation and normal left ventricular function. N Engl J Med. 1994;331:689–94.. ### Response: aortic.


Instruction: What is a factor associated with progression to aortic valve replacement?

Output: Chronic aortic insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a factor associated with progression to aortic valve replacement?. ### Response: Chronic aortic insufficiency.


Instruction: What is an example of a long-term prospective follow-up study?

Output: se-vere asymptomatic chronic aortic regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a long-term prospective follow-up study?. ### Response: se-vere asymptomatic chronic aortic regurgitation.


Instruction: When was Circulation. 2021;143:e72–e227?

Output: February 2, 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation. 2021;143:e72–e227?. ### Response: February 2, 2021.


Instruction: What is the DOI of the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: 10.1161/CIR.0000000000000923 e168CLINICAL STATEMENTS  AND GUIDELINES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI of the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: 10.1161/CIR.0000000000000923 e168CLINICAL STATEMENTS  AND GUIDELINES.


Instruction: What may choose to undergo pregnancy without valve intervention?

Output: women with severe asymptomatic AS, normal LV systolic function, and normal bio-markers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may choose to undergo pregnancy without valve intervention?. ### Response: women with severe asymptomatic AS, normal LV systolic function, and normal bio-markers.


Instruction: What must be balanced against the risk of mechanical valve complica-tions during pregnancy or the long-term risks of a bioprosthetic valve?

Output: dete-rioration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be balanced against the risk of mechanical valve complica-tions during pregnancy or the long-term risks of a bioprosthetic valve?. ### Response: dete-rioration.


Instruction: What is the threshold for valve operation for valve regurgitation higher in the asymptomatic patient who might ever become pregnant than in patients who will not become pregnant?

Output: there always is the possibility that valve repair will not be successful and a prosthetic valve will be needed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the threshold for valve operation for valve regurgitation higher in the asymptomatic patient who might ever become pregnant than in patients who will not become pregnant?. ### Response: there always is the possibility that valve repair will not be successful and a prosthetic valve will be needed.


Instruction: Why is a prosthetic valve needed?

Output: there always is the possibility that valve repair will not be successful

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is a prosthetic valve needed?. ### Response: there always is the possibility that valve repair will not be successful.


Instruction: Most patients with asymp-tomatic severe MR tolerate the hemodynamic changes of pregnancy?

Output: higher in the asymptomatic patient who might ever become pregnant than in patients who will not become pregnant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most patients with asymp-tomatic severe MR tolerate the hemodynamic changes of pregnancy?. ### Response: higher in the asymptomatic patient who might ever become pregnant than in patients who will not become pregnant.


Instruction: There is no evidence for acceleration of what?

Output: LV dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no evidence for acceleration of what?. ### Response: LV dysfunction.


Instruction: There is no evidence for acceleration of LV dysfunction during what stage of pregnancy?

Output: preg-nancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no evidence for acceleration of LV dysfunction during what stage of pregnancy?. ### Response: preg-nancy.


Instruction: What are two high-risk features for development of HF during pregnancy in women with MR?

Output: depressed LV systolic function and pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two high-risk features for development of HF during pregnancy in women with MR?. ### Response: depressed LV systolic function and pulmonary hypertension.


Instruction: What does TTE stand for?

Output: transthoracic echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does TTE stand for?. ### Response: transthoracic echocardiography.


Instruction: What is considered in the decision-making process in high risk asymptomatic women with severe MR?

Output: estimated surgical risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered in the decision-making process in high risk asymptomatic women with severe MR?. ### Response: estimated surgical risk.


Instruction: What indicates transthoracic echocardiography?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates transthoracic echocardiography?. ### Response: TTE.


Instruction: What indicates valvular heart disease?

Output: VHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates valvular heart disease?. ### Response: VHD.


Instruction: What are the Guidelines for the Primary Prevention of Stroke 3807Miller E, Sacco RL?

Output: Definition and evaluation of transient ischemic attack

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Guidelines for the Primary Prevention of Stroke 3807Miller E, Sacco RL?. ### Response: Definition and evaluation of transient ischemic attack.


Instruction: What is the definition and evaluation of transient ischemic attack?

Output: a scientific statement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition and evaluation of transient ischemic attack?. ### Response: a scientific statement.


Instruction: What are the Councils on Cardiovascular Radiology and Intervention?

Output: Council on Cardiovascular Surgery and Anesthesia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Councils on Cardiovascular Radiology and Intervention?. ### Response: Council on Cardiovascular Surgery and Anesthesia.


Instruction: What is the Interdisciplinary Council on Peripheral Vascular Disease?

Output: a scientific statement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Interdisciplinary Council on Peripheral Vascular Disease?. ### Response: a scientific statement.


Instruction: What are the guidelines for the prevention of stroke in women from the American Heart Association/American Stroke Association?

Output: a statement for healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the guidelines for the prevention of stroke in women from the American Heart Association/American Stroke Association?. ### Response: a statement for healthcare professionals.


Instruction: What is Burt BA's definition of risk?

Output: J Dent Educ. 2001;65:1007–1008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Burt BA's definition of risk?. ### Response: J Dent Educ. 2001;65:1007–1008.


Instruction: What is the name of the American Stroke Association's journal?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the American Stroke Association's journal?. ### Response: JAMA.


Instruction: What is Burt BA's title?

Output: Definitions of risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Burt BA's title?. ### Response: Definitions of risk.


Instruction: Who wrote the journal "Definitions of risk"?

Output: Burt BA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the journal "Definitions of risk"?. ### Response: Burt BA.


Instruction: When was "The effectiveness of personalized coronary heart disease and stroke risk communication" published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was "The effectiveness of personalized coronary heart disease and stroke risk communication" published?. ### Response: 2011.


Instruction: What is the name of the scientific statement for healthcare profesionals from the American Heart Association and the American College of Cardiology?

Output: AHA/ACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the scientific statement for healthcare profesionals from the American Heart Association and the American College of Cardiology?. ### Response: AHA/ACC.


Instruction: When did J Am Coll Cardiol. 1999;34:1348-1359?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 1999;34:1348-1359?. ### Response: 1999.


Instruction: What is a score for predicting risk of death from cardiovascular disease in adults with raised blood pressure based on individual patient data from randomised controlled trials?

Output: 15. Pocock SJ, McCormack V , Gueyffier F, Boutitie F, Fagard RH, Boissel JP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a score for predicting risk of death from cardiovascular disease in adults with raised blood pressure based on individual patient data from randomised controlled trials?. ### Response: 15. Pocock SJ, McCormack V , Gueyffier F, Boutitie F, Fagard RH, Boissel JP.


Instruction: What study did the Framingham Study use to determine the probability of stroke?

Output: the Framingham Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study did the Framingham Study use to determine the probability of stroke?. ### Response: the Framingham Heart Study.


Instruction: How many strokes were there in 1991?

Output: 312–318

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 1991?. ### Response: 312–318.


Instruction: What type of data did the BMJ analyze?

Output: randomised controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of data did the BMJ analyze?. ### Response: randomised controlled trials.


Instruction: What is the name of the person who wrote this article?

Output: Meschia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who wrote this article?. ### Response: Meschia.


Instruction: What is one of the names of the people who wrote it?

Output: Meschia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the names of the people who wrote it?. ### Response: Meschia.


Instruction: Who is the author of the article that was written by this person?

Output: D’Agostino RB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the article that was written by this person?. ### Response: D’Agostino RB.


Instruction: What is a meta-analysis of common carotid intima-media thickness measurements in cardiovascular risk prediction?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of common carotid intima-media thickness measurements in cardiovascular risk prediction?. ### Response: JAMA.


Instruction: What is a risk score for predicting stroke or death in individuals with stroke?

Output: the Framingham Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk score for predicting stroke or death in individuals with stroke?. ### Response: the Framingham Heart Study.


Instruction: What is the Framingham study?

Output: Stroke risk pro-file: adjustment for antihypertensive medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Framingham study?. ### Response: Stroke risk pro-file: adjustment for antihypertensive medication.


Instruction: What is the risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the commu-nity: the Framingham Heart Study?

Output: 19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the commu-nity: the Framingham Heart Study?. ### Response: 19.


Instruction: What is a class IIb aneurysm rupture risk?

Output: Level ofEvidence B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIb aneurysm rupture risk?. ### Response: Level ofEvidence B.


Instruction: What is the Level of Evidence B?

Output: Class IIb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence B?. ### Response: Class IIb.


Instruction: A diet rich in what is recommended?

Output: vegetables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A diet rich in what is recommended?. ### Response: vegetables.


Instruction: What may lower the risk of aSAH?

Output: Consumption of a diet rich in vegetables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may lower the risk of aSAH?. ### Response: Consumption of a diet rich in vegetables.


Instruction: What may be reasonable to offer noninvasive screeningto patients with familial (at least 1 first-degreerelative) aSAAH and/or a history of sAH to evaluate?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable to offer noninvasive screeningto patients with familial (at least 1 first-degreerelative) aSAAH and/or a history of sAH to evaluate?. ### Response: 6.


Instruction: What should be administered to all patients with aSAH?

Output: Oral nimodipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be administered to all patients with aSAH?. ### Response: Oral nimodipine.


Instruction: What is recommended to prevent ischemic stroke and intracerebralhemorrhage?

Output: Treatment of high blood pressure with antihypertensive medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to prevent ischemic stroke and intracerebralhemorrhage?. ### Response: Treatment of high blood pressure with antihypertensive medication.


Instruction: What has been shown toimprove neurological outcomes but not cerebral vasospasm?

Output: Oral nimodipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown toimprove neurological outcomes but not cerebral vasospasm?. ### Response: Oral nimodipine.


Instruction: Tobacco use and alcohol misuse should be avoided to reduce the risk of what?

Output: aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tobacco use and alcohol misuse should be avoided to reduce the risk of what?. ### Response: aSAH.


Instruction: After any aneurysm repair, what is generally recommended to identify remnants or recurrence that may require treatment?

Output: immediate cerebrovascular imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After any aneurysm repair, what is generally recommended to identify remnants or recurrence that may require treatment?. ### Response: immediate cerebrovascular imaging.


Instruction: What should be determined quickly by using simple validated scales?

Output: The initial clinical severity of aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be determined quickly by using simple validated scales?. ### Response: The initial clinical severity of aSAH.


Instruction: What is the most useful indicator of outcome after aSAH?

Output: The initial clinical severity of aSAH should be determined rapidly by use of simple validated scales

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most useful indicator of outcome after aSAH?. ### Response: The initial clinical severity of aSAH should be determined rapidly by use of simple validated scales.


Instruction: The risk of early aneurysm rebleeding is what?

Output: high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The risk of early aneurysm rebleeding is what?. ### Response: high.


Instruction: What is the risk of early aneurysm rebleeding?

Output: high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of early aneurysm rebleeding?. ### Response: high.


Instruction: What is a medical emergency that is frequently misdiagnosed?

Output: aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a medical emergency that is frequently misdiagnosed?. ### Response: aSAH.


Instruction: A high level of suspicion for aSAH should exist in patients with acute onset of what?

Output: severe headache

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A high level of suspicion for aSAH should exist in patients with acute onset of what?. ### Response: severe headache.


Instruction: Acute diagnostic workup should include what type of CT?

Output: noncontrast head CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Acute diagnostic workup should include what type of CT?. ### Response: noncontrast head CT.


Instruction: What should be followed by lumbarpuncture if nondiagnostic?

Output: noncontrast head CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be followed by lumbarpuncture if nondiagnostic?. ### Response: noncontrast head CT.


Instruction: DSA with 3-dimensional rotational angiography is indicated for detection of aneurysm in what patient?

Output: patients with aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: DSA with 3-dimensional rotational angiography is indicated for detection of aneurysm in what patient?. ### Response: patients with aSAH.


Instruction: What should be monitored between the time of aSAH symptom onset and aneurysm obliteration?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be monitored between the time of aSAH symptom onset and aneurysm obliteration?. ### Response: blood pressure.


Instruction: What should be controlled with a titratableagent to balance the risk of stroke, hypertension-related rebleeding, and maintenance of cerebral perfusion pressure?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be controlled with a titratableagent to balance the risk of stroke, hypertension-related rebleeding, and maintenance of cerebral perfusion pressure?. ### Response: blood pressure.


Instruction: When should surgical clipping or endovascular coiling of the ruptured aneurysm be performed?

Output: as early as feasible

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should surgical clipping or endovascular coiling of the ruptured aneurysm be performed?. ### Response: as early as feasible.


Instruction: What is performed as early as possible in the majority of patients to reduce the rate of rebleeding after aSAH?

Output: Surgical clipping or endovascular coiling of the ruptured aneurysm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed as early as possible in the majority of patients to reduce the rate of rebleeding after aSAH?. ### Response: Surgical clipping or endovascular coiling of the ruptured aneurysm.


Instruction: What are two examples of revascularization?

Output: coronary artery bypass surgery and PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two examples of revascularization?. ### Response: coronary artery bypass surgery and PCI.


Instruction: What is one of the more innovative and unexplored aspects of PCI?

Output: AUC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the more innovative and unexplored aspects of PCI?. ### Response: AUC.


Instruction: How many previous attempts to construct performance measures have not relied heavily on AUC?

Output: 19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many previous attempts to construct performance measures have not relied heavily on AUC?. ### Response: 19.


Instruction: What is one of the more innovative andunexplored aspects of the performance measure set?

Output: AUC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the more innovative andunexplored aspects of the performance measure set?. ### Response: AUC.


Instruction: Thewriting committee approached the creation of this measure cautiously to maximize its value to what?

Output: users

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Thewriting committee approached the creation of this measure cautiously to maximize its value to what?. ### Response: users.


Instruction: What are elective PCIs that occur in nonacute settings classified as according to AUC 19?

Output: appropriate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are elective PCIs that occur in nonacute settings classified as according to AUC 19?. ### Response: appropriate.


Instruction: What do we focus on to optimize our opportunity to improve?

Output: elective PCIs that occur in nonacute settings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we focus on to optimize our opportunity to improve?. ### Response: elective PCIs that occur in nonacute settings.


Instruction: What is the definition of appropriate according to the AUC?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of appropriate according to the AUC?. ### Response: uncertain.


Instruction: What are created to ensure that the document and AUC are harmonised?

Output: guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are created to ensure that the document and AUC are harmonised?. ### Response: guidelines.


Instruction: How are the AUC created?

Output: via amodiﬁ ed Delphi approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the AUC created?. ### Response: via amodiﬁ ed Delphi approach.


Instruction: What do experts reach after being presented with speci fic clinical sce-narios that focus on coronary anatomy?

Output: consensus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do experts reach after being presented with speci fic clinical sce-narios that focus on coronary anatomy?. ### Response: consensus.


Instruction: What does the AUC stand for?

Output: Class IIb recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the AUC stand for?. ### Response: Class IIb recommendation.


Instruction: What do the guidelines for PCI categorize the usefulness of?

Output: survivalbeneﬁt in asymptomatic patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the guidelines for PCI categorize the usefulness of?. ### Response: survivalbeneﬁt in asymptomatic patients.