Instruction: How much perfusion defect by myocardialperfusion stress?

Output: >20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much perfusion defect by myocardialperfusion stress?. ### Response: >20%.


Instruction: What type of hemodynamic eval-uation is reasonable in patients with mild–moderate LV systolic dysfunction?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hemodynamic eval-uation is reasonable in patients with mild–moderate LV systolic dysfunction?. ### Response: CABG.


Instruction: What percentage of diameter stenosis is significant with multives-sel CAD or proximal LAD?

Output: >70%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of diameter stenosis is significant with multives-sel CAD or proximal LAD?. ### Response: >70%.


Instruction: What type of stenosis occurs whenviable myocardium is present in the region of intendedrevascularization?

Output: proximal LAD coronary artery stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stenosis occurs whenviable myocardium is present in the region of intendedrevascularization?. ### Response: proximal LAD coronary artery stenosis.


Instruction: What is the level of evidence for CABG with a left internal mammary artery graft to improve survival?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for CABG with a left internal mammary artery graft to improve survival?. ### Response: B.


Instruction: What percentage of the stenosis in theproximal LAD artery is significant?

Output: >70%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the stenosis in theproximal LAD artery is significant?. ### Response: >70%.


Instruction: What is the level of evidence for extensiveischemia?

Output: 412,987,993,994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for extensiveischemia?. ### Response: 412,987,993,994.


Instruction: Why is it reasonable to choose CABG over PCI?

Output: to im-prove survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is it reasonable to choose CABG over PCI?. ### Response: to im-prove survival.


Instruction: What type of graft can be anastomosed to the LADartery?

Output: LIMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of graft can be anastomosed to the LADartery?. ### Response: LIMA.


Instruction: What is probably recommended in preference to PCI?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is probably recommended in preference to PCI?. ### Response: CABG.


Instruction: What can be anastomosed to the LADartery?

Output: aLIMA graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be anastomosed to the LADartery?. ### Response: aLIMA graft.


Instruction: What is the usefulness of CABG to improve survival in patients with significant diame-ter stenoses in 2 major coronary arteries?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the usefulness of CABG to improve survival in patients with significant diame-ter stenoses in 2 major coronary arteries?. ### Response: uncertain.


Instruction: What does PCI do to improve survival?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PCI do to improve survival?. ### Response: CABG.


Instruction: What is the use of PCI in patients with 2- or 3-vessel CAD?

Output: uncer-tain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use of PCI in patients with 2- or 3-vessel CAD?. ### Response: uncer-tain.


Instruction: When was the Circulation December 18/25, 2012?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation December 18/25, 2012?. ### Response: May 1, 2023.


Instruction: What was rated as a minor concern?

Output: Coherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as a minor concern?. ### Response: Coherence.


Instruction: What was the majority demons trating patients’ lack of understanding of?

Output: their prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the majority demons trating patients’ lack of understanding of?. ### Response: their prognosis.


Instruction: What did the majority demons treat?

Output: patients’ lack of understanding of their prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the majority demons treat?. ### Response: patients’ lack of understanding of their prognosis.


Instruction: Why was the relevance of the subfinding very high?

Output: to the focus of the review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the relevance of the subfinding very high?. ### Response: to the focus of the review.


Instruction: How many studies were included in the review?

Output: five

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included in the review?. ### Response: five.


Instruction: What was rated as no concerns?

Output: Adequacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as no concerns?. ### Response: Adequacy.


Instruction: How was confidence rated?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was confidence rated?. ### Response: moderate.


Instruction: What was the overall assessment of confidence?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall assessment of confidence?. ### Response: moderate.


Instruction: What was downgraded by one increment due to moderate methodological and minor coherence limitations?

Output: The overall assessment of confidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was downgraded by one increment due to moderate methodological and minor coherence limitations?. ### Response: The overall assessment of confidence.


Instruction: Patients preferred not to know more about what?

Output: their prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients preferred not to know more about what?. ### Response: their prognosis.


Instruction: What was a common preoccupation of patients with Parkinson's?

Output: Thinking about the future

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a common preoccupation of patients with Parkinson's?. ### Response: Thinking about the future.


Instruction: What did some carers feel they were inadequately informed by?

Output: healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some carers feel they were inadequately informed by?. ### Response: healthcare professionals.


Instruction: What is a common preoccupation of patients?

Output: Thinking about the future

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common preoccupation of patients?. ### Response: Thinking about the future.


Instruction: How many studies were based on this subfinding?

Output: seven

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were based on this subfinding?. ### Response: seven.


Instruction: What was rated moderate overall?

Output: Methodological limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated moderate overall?. ### Response: Methodological limitations.


Instruction: How many studies were rated moderate limitations?

Output: seven

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were rated moderate limitations?. ### Response: seven.


Instruction: What were the limitations in context, role of researcher, data analysis, research methods rigour and/or data richness?

Output: limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the limitations in context, role of researcher, data analysis, research methods rigour and/or data richness?. ### Response: limitations.


Instruction: How many studies were rated as having serious limitations?

Output: Three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were rated as having serious limitations?. ### Response: Three.


Instruction: What were the limitations of three studies?

Output: lack of rigour of  research methods, study aims, and relevance of findings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the limitations of three studies?. ### Response: lack of rigour of  research methods, study aims, and relevance of findings.


Instruction: Why were three studies rated serious?

Output: lack of rigour of  research methods, study aims, and relevance of findings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were three studies rated serious?. ### Response: lack of rigour of  research methods, study aims, and relevance of findings.


Instruction: What was rated minor concerns overall?

Output: Coherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated minor concerns overall?. ### Response: Coherence.


Instruction: What was good in that papers reported a range of things?

Output: Agreement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was good in that papers reported a range of things?. ### Response: Agreement.


Instruction: What is expected in people's attitudes?

Output: Variability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is expected in people's attitudes?. ### Response: Variability.


Instruction: What was rated as minor concerns?

Output: Coherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as minor concerns?. ### Response: Coherence.


Instruction: How was relevance rated?

Output: no or very minor concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was relevance rated?. ### Response: no or very minor concerns.


Instruction: What was rated as no or very minor concerns?

Output: Relevance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as no or very minor concerns?. ### Response: Relevance.


Instruction: The sub finding was supported by a number of studies.

Output: Adequacy was rated as no concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The sub finding was supported by a number of studies.. ### Response: Adequacy was rated as no concerns.


Instruction: What was supported by a number of studies?

Output: The subfinding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was supported by a number of studies?. ### Response: The subfinding.


Instruction: The finding was descriptive and supported by the richness of what?

Output: data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The finding was descriptive and supported by the richness of what?. ### Response: data.


Instruction: What are some of the limitations of coherence?

Output: moderate methodological and minor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the limitations of coherence?. ### Response: moderate methodological and minor.


Instruction: What did Bozkurt and colleagues do on December 6, 2016?

Output: 134:e535–e578

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Bozkurt and colleagues do on December 6, 2016?. ### Response: 134:e535–e578.


Instruction: What diet did Wolk A, Mittleman MA, Levitan EB, Wolken A, and Mittlemen MA use?

Output: DASH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What diet did Wolk A, Mittleman MA, Levitan EB, Wolken A, and Mittlemen MA use?. ### Response: DASH.


Instruction: How old are men who follow the Dietary Approaches to Stop Hypertension diet more likely to develop heart failure?

Output: 45 to 79 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are men who follow the Dietary Approaches to Stop Hypertension diet more likely to develop heart failure?. ### Response: 45 to 79 years.


Instruction: What is the name of the diet that has been linked to the incidence of heart failure in men?

Output: Mediterranean diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the diet that has been linked to the incidence of heart failure in men?. ### Response: Mediterranean diet.


Instruction: When was the Am J Cardiol.104:1416-1420 published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol.104:1416-1420 published?. ### Response: 2009.


Instruction: What diet did the PREDIMED Study Investigators study?

Output: Mediterranean

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What diet did the PREDIMED Study Investigators study?. ### Response: Mediterranean.


Instruction: What did the Mediterranean diet have on heart failure bio-markers?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Mediterranean diet have on heart failure bio-markers?. ### Response: Effect.


Instruction: What is the name of the randomized sample from the PREDIMED trial?

Output: PREDIMED Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized sample from the PREDIMED trial?. ### Response: PREDIMED Study Investigators.


Instruction: When did Eur J Heart Fail issue 16:543-550?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Heart Fail issue 16:543-550?. ### Response: 2014.


Instruction: How many days did it take to recover from a myocardial infarction?

Output: 327

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days did it take to recover from a myocardial infarction?. ### Response: 327.


Instruction: What was the final report of the Lyon Diet Heart Study?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the final report of the Lyon Diet Heart Study?. ### Response: 1999.


Instruction: What is the name of the study?

Output: Lyon Diet Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: Lyon Diet Heart Study.


Instruction: What does the Women’s Health Initiative do?

Output: Mediterranean and DASH diet scores and mortality in women with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Women’s Health Initiative do?. ### Response: Mediterranean and DASH diet scores and mortality in women with heart failure.


Instruction: What is the name of the organization that studies DASH diet scores and mortality in women with heart failure?

Output: Women’s Health Initiative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that studies DASH diet scores and mortality in women with heart failure?. ### Response: Women’s Health Initiative.


Instruction: What type of diet is associated with diastolic heart function in chronic heart failure patients?

Output: Low-sodium DASH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet is associated with diastolic heart function in chronic heart failure patients?. ### Response: Low-sodium DASH.


Instruction: What is the name of the study that examined the relationship between Mediterranean type diet and diatrogenic heart function?

Output: PREDIMED Study Investigators. Effect of the Mediterranean diet on heart failure bio-markers: a randomized sample from the PREDIMED trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the relationship between Mediterranean type diet and diatrogenic heart function?. ### Response: PREDIMED Study Investigators. Effect of the Mediterranean diet on heart failure bio-markers: a randomized sample from the PREDIMED trial.


Instruction: When did Heart Vessels publish its 27th issue?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Heart Vessels publish its 27th issue?. ### Response: 2012.


Instruction: What diet reduces blood pressure, arterial stiffness, and oxidative stress in hypertensive heart failure with preserved ejection fraction?

Output: Low-sodium Dietary Approaches to Stop Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What diet reduces blood pressure, arterial stiffness, and oxidative stress in hypertensive heart failure with preserved ejection fraction?. ### Response: Low-sodium Dietary Approaches to Stop Hypertension.


Instruction: What year did Hypertension.60:1200-1206?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Hypertension.60:1200-1206?. ### Response: 2012.


Instruction: What diet improves diastolic function and ventricular-arterial coupling in hypertensive heart failure with preserved ejection frac-tion?

Output: Low-sodium DASH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What diet improves diastolic function and ventricular-arterial coupling in hypertensive heart failure with preserved ejection frac-tion?. ### Response: Low-sodium DASH.


Instruction: What does low-sodium DASH diet improve?

Output: diastolic function and ventricular-arterial coupling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does low-sodium DASH diet improve?. ### Response: diastolic function and ventricular-arterial coupling.


Instruction: What is the name of the journal that deals with heart failure?

Output: CIRCHEARTFAILURE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that deals with heart failure?. ### Response: CIRCHEARTFAILURE.


Instruction: What year did Circ Heart Fail issue 6:1109-1111?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circ Heart Fail issue 6:1109-1111?. ### Response: 2013.


Instruction: How were the RCTs identified in the evidence review evaluated?

Output: in detail

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the RCTs identified in the evidence review evaluated?. ### Response: in detail.


Instruction: What are the strengths and weaknesses of the data in the literature summarized above?

Output: strengths and w eakness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the strengths and weaknesses of the data in the literature summarized above?. ### Response: strengths and w eakness.


Instruction: The benefits of taking once-daily spironolactone outweigh the potential for what?

Output: AEs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The benefits of taking once-daily spironolactone outweigh the potential for what?. ### Response: AEs.


Instruction: What drug outweighs the potential for AEs when the RHT patient is chosen carefully and monitored closely as therapy is initiated?

Output: spironolactone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug outweighs the potential for AEs when the RHT patient is chosen carefully and monitored closely as therapy is initiated?. ### Response: spironolactone.


Instruction: Patients who meet the criteria for RHT are at increased risk for fatal and non-fatal cardiovascular events?

Output: Epidemiologically

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients who meet the criteria for RHT are at increased risk for fatal and non-fatal cardiovascular events?. ### Response: Epidemiologically.


Instruction: What is there no outcome data on?

Output: which fourth -line drug will have the greatest effect on cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there no outcome data on?. ### Response: which fourth -line drug will have the greatest effect on cardiovascular events.


Instruction: What is there no data to guide the clinical practitioner on?

Output: which fourth -line drug will have the greatest effect on cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there no data to guide the clinical practitioner on?. ### Response: which fourth -line drug will have the greatest effect on cardiovascular events.


Instruction: What is little known about the impact of age, gender, and comorbidities?

Output: response to specific medications in patients with RHT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is little known about the impact of age, gender, and comorbidities?. ### Response: response to specific medications in patients with RHT.


Instruction: What is the effect of diabetes, CKD, CAD, or prior stroke on the response to specific medications in RHT patients?

Output: little is known

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of diabetes, CKD, CAD, or prior stroke on the response to specific medications in RHT patients?. ### Response: little is known.


Instruction: What is the association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunc-tion: implications for screening?

Output: 37

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunc-tion: implications for screening?. ### Response: 37.


Instruction: What is anwaruddin S, Lloyd-Jones DM, Baggish A?

Output: Renal function, con-gestive heart failure, and amino-terminal pro-brain natriuretic peptide measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is anwaruddin S, Lloyd-Jones DM, Baggish A?. ### Response: Renal function, con-gestive heart failure, and amino-terminal pro-brain natriuretic peptide measurement.


Instruction: What is the name of the PROBNP Investigation of Dyspnea in the Emergency Department Study?

Output: PRIDE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PROBNP Investigation of Dyspnea in the Emergency Department Study?. ### Response: PRIDE.


Instruction: What is an impact of age and gender on plasma brain natriuretic peptide concentration?

Output: Impact of age and sex on plasma natriuretic peptide levels in healthy adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an impact of age and gender on plasma brain natriuretic peptide concentration?. ### Response: Impact of age and sex on plasma natriuretic peptide levels in healthy adults.


Instruction: What is the impact of age and gender on plasma natriuretic peptide concentration?

Output: Impact of age and sex on plasma natriuretic peptide levels in healthy adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of age and gender on plasma natriuretic peptide concentration?. ### Response: Impact of age and sex on plasma natriuretic peptide levels in healthy adults.


Instruction: What is ahajournals.org about?

Output: Impact of age and sex on plasma natriuretic peptide levels in healthy adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ahajournals.org about?. ### Response: Impact of age and sex on plasma natriuretic peptide levels in healthy adults.


Instruction: What is reasonable in patients with a well-defined history of nonanaphylactoid reactions to penicillins?

Output: Cefazolin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in patients with a well-defined history of nonanaphylactoid reactions to penicillins?. ### Response: Cefazolin.


Instruction: What should be done in every case in which vancomycin is considered for treatment of MSSA IE?

Output: Allergy evaluation for tolerance to β-lactam therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be done in every case in which vancomycin is considered for treatment of MSSA IE?. ### Response: Allergy evaluation for tolerance to β-lactam therapy.


Instruction: What is not recommended because of increased IE relapse rate?

Output: Clindamycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended because of increased IE relapse rate?. ### Response: Clindamycin.


Instruction: What is a reasonable alternative to vancomy-cin for NVE caused by MSSA?

Output: Daptomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable alternative to vancomy-cin for NVE caused by MSSA?. ### Response: Daptomycin.


Instruction: What is MSSA?

Output: Class IIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MSSA?. ### Response: Class IIa.


Instruction: What is discouraged because of the high rates of intrinsic gentamicin resistance?

Output: combination therapy with gentamicin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is discouraged because of the high rates of intrinsic gentamicin resistance?. ### Response: combination therapy with gentamicin therapy.


Instruction: Most staphylococci are highly susceptible to what?

Output: rifampin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most staphylococci are highly susceptible to what?. ### Response: rifampin.


Instruction: What are staphylococci highly susceptible to?

Output: rifampin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are staphylococci highly susceptible to?. ### Response: rifampin.


Instruction: What does resistance develop rapidly when rifampin is used alone?

Output: Although most staphylococci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does resistance develop rapidly when rifampin is used alone?. ### Response: Although most staphylococci.


Instruction: The in vivo efficacy of rfampin in combination with nafcillin, oxacillin, vancomycin, trimethoprim, and aminoglycosides is highly variable?

Output: 162

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The in vivo efficacy of rfampin in combination with nafcillin, oxacillin, vancomycin, trimethoprim, and aminoglycosides is highly variable?. ### Response: 162.


Instruction: What has adjunct therapy for S aureus NVE been associated with?

Output: higher rates of adverse events (primarily hepatotox-icity) and a significantly lower survival rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has adjunct therapy for S aureus NVE been associated with?. ### Response: higher rates of adverse events (primarily hepatotox-icity) and a significantly lower survival rate.


Instruction: What is not recommended for treatment of staphylococcal NVE?

Output: routine use of rifampin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for treatment of staphylococcal NVE?. ### Response: routine use of rifampin.


Instruction: What did a prospective trial in patients with IE caused by MRSA fail to demonstrate?

Output: the addition of rifampin to vancomycin either enhanced survival or reduced the duration of bacteremia compared with treatment with vancomycin alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a prospective trial in patients with IE caused by MRSA fail to demonstrate?. ### Response: the addition of rifampin to vancomycin either enhanced survival or reduced the duration of bacteremia compared with treatment with vancomycin alone.


Instruction: What did the addition of rifampin to vancomycin increase or reduce compared with treatment with?

Output: bacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the addition of rifampin to vancomycin increase or reduce compared with treatment with?. ### Response: bacteremia.


Instruction: Which drug is often used in native valve S aureus IE when infection is complicated?

Output: Rifampin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug is often used in native valve S aureus IE when infection is complicated?. ### Response: Rifampin.


Instruction: What is involved in valve S aureus IE when it is complicated by involvement of selected anatomic sites where rifampin penetrates effic-tively?

Output: Rifampin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is involved in valve S aureus IE when it is complicated by involvement of selected anatomic sites where rifampin penetrates effic-tively?. ### Response: Rifampin.


Instruction: What is one anatomic site that is involved with involvement of ribampin?

Output: bone, joint, cerebrospinal fluid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one anatomic site that is involved with involvement of ribampin?. ### Response: bone, joint, cerebrospinal fluid.


Instruction: No standard therapies exist for the treatment of what?

Output: S aureus IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No standard therapies exist for the treatment of what?. ### Response: S aureus IE.


Instruction: What is the classification of vancomy-cin isolates?

Output: reduced susceptibility (hVISA), intermediate resistance (VISA), and high-level resistance (VRSA).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the classification of vancomy-cin isolates?. ### Response: reduced susceptibility (hVISA), intermediate resistance (VISA), and high-level resistance (VRSA)..


Instruction: What are the designations of reduced susceptibility (hVISA), intermediate resistance (VISA) and high-level resistance (VRSA)?

Output: Classification of these isolates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the designations of reduced susceptibility (hVISA), intermediate resistance (VISA) and high-level resistance (VRSA)?. ### Response: Classification of these isolates.


Instruction: The limited number of patients reported to have IE caused by these isolates precludes what?

Output: specific treatment recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The limited number of patients reported to have IE caused by these isolates precludes what?. ### Response: specific treatment recommendations.


Instruction: What should be managed in conjunction with an infectious diseases consultant?

Output: these infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be managed in conjunction with an infectious diseases consultant?. ### Response: these infections.


Instruction: What did Markowitz et al165 show was inferior to vancomycin in the treat-ment of invasive S aureus infections?

Output: trimethoprim-sulfamethoxazole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Markowitz et al165 show was inferior to vancomycin in the treat-ment of invasive S aureus infections?. ### Response: trimethoprim-sulfamethoxazole.


Instruction: In what situations is trimethoprim-sulfamethazole sometimes used?

Output: salvage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what situations is trimethoprim-sulfamethazole sometimes used?. ### Response: salvage.


Instruction: Where did all treatment failures with trimethoprim-sulfamenoxazole occur?

Output: patients infected with MSSA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did all treatment failures with trimethoprim-sulfamenoxazole occur?. ### Response: patients infected with MSSA.


Instruction: Patients with MSSA infection were uniformly cured of what?

Output: treatment failures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with MSSA infection were uniformly cured of what?. ### Response: treatment failures.


Instruction: What may be attenuated by thymidine release from damaged host cells?

Output: The efficacy of trimethoprim-sulfamethoxazole and other folate antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be attenuated by thymidine release from damaged host cells?. ### Response: The efficacy of trimethoprim-sulfamethoxazole and other folate antagonists.


Instruction: What is a site of tissue damage such as abscesses?

Output: damaged host cells

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a site of tissue damage such as abscesses?. ### Response: damaged host cells.


Instruction: What is the name of the American College of Cardiology clinical expert consensus document on standards for acqui-sition, measurement and reporting of cardiac imaging?

Output: IVUS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the American College of Cardiology clinical expert consensus document on standards for acqui-sition, measurement and reporting of cardiac imaging?. ### Response: IVUS.


Instruction: What is the consensus document on standards for acqui-sition, measurement and reporting of intravascular ultrasound studies called?

Output: IVUS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the consensus document on standards for acqui-sition, measurement and reporting of intravascular ultrasound studies called?. ### Response: IVUS.


Instruction: What was a report of the American College of Cardiology task force onclinical expert consensus documents?

Output: American College ofCardiology clinical expert consensus document on standards for acqui-sition, measurement and reporting of intravascular ultrasound studies(IVUS).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a report of the American College of Cardiology task force onclinical expert consensus documents?. ### Response: American College ofCardiology clinical expert consensus document on standards for acqui-sition, measurement and reporting of intravascular ultrasound studies(IVUS)..


Instruction: What did OCT assessment of thin-capfibroatheroma distribution in native coronary arteries do?

Output: Comparison of vascular responseafter sirolimus-eluting stent implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did OCT assessment of thin-capfibroatheroma distribution in native coronary arteries do?. ### Response: Comparison of vascular responseafter sirolimus-eluting stent implantation.


Instruction: What did Imanishi T, Tanaka A, et al. determine by optical coherence tomography inunstable angina pectoris?

Output: Clinical classification andplaque morphology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Imanishi T, Tanaka A, et al. determine by optical coherence tomography inunstable angina pectoris?. ### Response: Clinical classification andplaque morphology.


Instruction: What was evaluated with optical coherence tomography?

Output: Neointimal coverage of bare-metal andsirolimus-eluting stents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was evaluated with optical coherence tomography?. ### Response: Neointimal coverage of bare-metal andsirolimus-eluting stents.


Instruction: What did Ma FY, Luo W, and Kitabata H do?

Output: Neointimal coverage of bare-metal andsirolimus-eluting stents evaluated with optical coherence tomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Ma FY, Luo W, and Kitabata H do?. ### Response: Neointimal coverage of bare-metal andsirolimus-eluting stents evaluated with optical coherence tomography.


Instruction: When did Kubo T, Imanishi T, Kitabasa H, et al. compare vascular response after sirolimus-eluting stent implantation?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Kubo T, Imanishi T, Kitabasa H, et al. compare vascular response after sirolimus-eluting stent implantation?. ### Response: 2008.


Instruction: What type of tomography study was conducted in 2008?

Output: intravascular optical coherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of tomography study was conducted in 2008?. ### Response: intravascular optical coherence.


Instruction: What is the name of the bioabsorbable everolimus-eluting coronary stent system?

Output: ABSORB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the bioabsorbable everolimus-eluting coronary stent system?. ### Response: ABSORB.


Instruction: In what year did the Lancet issue 373:897–910.514?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the Lancet issue 373:897–910.514?. ### Response: 2009.


Instruction: What type of lesions are treated with stenting after rotational atherectomy?

Output: calcified and complex lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of lesions are treated with stenting after rotational atherectomy?. ### Response: calcified and complex lesions.


Instruction: When was Circulation published?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation published?. ### Response: 1997.


Instruction: What is the name of the procedure used to treat calcified coronary lesions?

Output: drug-elutingstent implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used to treat calcified coronary lesions?. ### Response: drug-elutingstent implantation.


Instruction: What type of lesions are treated with calcified coronary lesions?

Output: complex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of lesions are treated with calcified coronary lesions?. ### Response: complex.


Instruction: What is the difference between percutaneous transluminal coronary angioplasty, atherectomy, cutting balloon atherotomy, and laser angioplasty?

Output: Meta-analysis of randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between percutaneous transluminal coronary angioplasty, atherectomy, cutting balloon atherotomy, and laser angioplasty?. ### Response: Meta-analysis of randomized trial.


Instruction: When was the J Am Coll Cardiol.43:936–42.517 published?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol.43:936–42.517 published?. ### Response: 2004.


Instruction: What is the difference between rotationalatherectomy and conventional balloon angioplasty?

Output: does notreduce recurrent in-stent restenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between rotationalatherectomy and conventional balloon angioplasty?. ### Response: does notreduce recurrent in-stent restenosis.


Instruction: What was the result of the Dilatation vsAblation Revascularization Trial Targeting Restenosis?

Output: Comparison of rotationalatherectomy with conventional balloon angioplasty in the prevention ofrestenosis of small coronary arteries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of the Dilatation vsAblation Revascularization Trial Targeting Restenosis?. ### Response: Comparison of rotationalatherectomy with conventional balloon angioplasty in the prevention ofrestenosis of small coronary arteries.


Instruction: What is the name of the study that compares excimerLaser, Rotational Atherectomy, and Balloon Angioplasty?

Output: ERBAC)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares excimerLaser, Rotational Atherectomy, and Balloon Angioplasty?. ### Response: ERBAC).


Instruction: When was the ERBAC study published?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ERBAC study published?. ### Response: 1997.


Instruction: What is a common cause of recurrent in-stent restenosis?

Output: Rotational atherectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of recurrent in-stent restenosis?. ### Response: Rotational atherectomy.


Instruction: What is the name of the versusrotational atherectomy for treatment of diffuse in-stent restenosis?

Output: ARTIST

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the versusrotational atherectomy for treatment of diffuse in-stent restenosis?. ### Response: ARTIST.


Instruction: What can cause urticarial skin reac-tions?

Output: Heparin and LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can cause urticarial skin reac-tions?. ### Response: Heparin and LMWH.


Instruction: What should be suspected in cases of skin necrosis at sites of injec-tion?

Output: HIT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be suspected in cases of skin necrosis at sites of injec-tion?. ### Response: HIT.


Instruction: How many different LMWH preparations did a patient develop skin reactions to?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many different LMWH preparations did a patient develop skin reactions to?. ### Response: three.


Instruction: How many different LMWH preparations did people develop skin reactions to?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many different LMWH preparations did people develop skin reactions to?. ### Response: three.


Instruction: What has been limited to to date studies on the effects of fondaparinux on bone metabolism?

Output: in vitro exper-iments using cultured osteoblasts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been limited to to date studies on the effects of fondaparinux on bone metabolism?. ### Response: in vitro exper-iments using cultured osteoblasts.


Instruction: In one study, fondaparainux was compared with heparin, dalteparin or what?

Output: enoxaparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In one study, fondaparainux was compared with heparin, dalteparin or what?. ### Response: enoxaparin.


Instruction: What did fondaparinux show higher mitochondrial activity and protein synthesis than?

Output: unexposed osteoblasts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did fondaparinux show higher mitochondrial activity and protein synthesis than?. ### Response: unexposed osteoblasts.


Instruction: What did therapeutically relevant concentrations of heparin, dalteparin or enoxaparain decrease?

Output: matrix collagen type 2 content and calcification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did therapeutically relevant concentrations of heparin, dalteparin or enoxaparain decrease?. ### Response: matrix collagen type 2 content and calcification.


Instruction: What did fonda-parinux have no effect on?

Output: osteo-blastic activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did fonda-parinux have no effect on?. ### Response: osteo-blastic activity.


Instruction: What did a second study compare the effects of fondaparinx and dalteparin on human osteoblasts in culture?

Output: inhibited osteoblast prolifera-tion, protein synthesis, and the decreased levels of osteocalcin and alkaline phosphatase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a second study compare the effects of fondaparinx and dalteparin on human osteoblasts in culture?. ### Response: inhibited osteoblast prolifera-tion, protein synthesis, and the decreased levels of osteocalcin and alkaline phosphatase.


Instruction: Dalteparain inhibited osteoblast prolifera-tion, protein synthesis, and the decreased levels of what?

Output: osteocalcin and alkaline phosphatase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dalteparain inhibited osteoblast prolifera-tion, protein synthesis, and the decreased levels of what?. ### Response: osteocalcin and alkaline phosphatase.


Instruction: What did fondaparinux have no effect on?

Output: osteo-blastic activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did fondaparinux have no effect on?. ### Response: osteo-blastic activity.


Instruction: What is not widely used in pregnancy because of insuffi cient safety data?

Output: fondaparinux

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not widely used in pregnancy because of insuffi cient safety data?. ### Response: fondaparinux.


Instruction: How many low levels of anti-Xa activity were detected in the umbilical cord blood in newborns of mothers treated with fondaparinux?

Output: 212

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many low levels of anti-Xa activity were detected in the umbilical cord blood in newborns of mothers treated with fondaparinux?. ### Response: 212.


Instruction: What is danaparoid Sodium a mixture of?

Output: glycosaminoglycans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is danaparoid Sodium a mixture of?. ### Response: glycosaminoglycans.


Instruction: What does danaparoid act as?

Output: anticoagulant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does danaparoid act as?. ### Response: anticoagulant.


Instruction: What is the role of heparan sulfate in anticoagulation?

Output: decreased matrix collagen type 2 content and calcification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of heparan sulfate in anticoagulation?. ### Response: decreased matrix collagen type 2 content and calcification.


Instruction: How long does half-life of danapraroid last?

Output: 25 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does half-life of danapraroid last?. ### Response: 25 h.


Instruction: What is the half-life of danaparoid?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the half-life of danaparoid?. ### Response: 25.


Instruction: What was shown to be effective for the prevention of venous thrombosis in high-risk patients?

Output: fondaparinux

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was shown to be effective for the prevention of venous thrombosis in high-risk patients?. ### Response: fondaparinux.


Instruction: What is the only agent that has been evaluated for HIT in a randomized clinical trial?

Output: Danaparoid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only agent that has been evaluated for HIT in a randomized clinical trial?. ### Response: Danaparoid.


Instruction: What was reported to be signifi cantly better than dextran?

Output: Danaparoid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reported to be signifi cantly better than dextran?. ### Response: Danaparoid.


Instruction: High success rates in the treatment of HIT have also been observed in what studies?

Output: retrospective studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: High success rates in the treatment of HIT have also been observed in what studies?. ### Response: retrospective studies.


Instruction: Danaparoid is approved for what in some countries?

Output: the treatment of HIT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Danaparoid is approved for what in some countries?. ### Response: the treatment of HIT.


Instruction: What country does Danaparoid not prolong the INR?

Output: United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What country does Danaparoid not prolong the INR?. ### Response: United States.


Instruction: What is the compound most bound to?

Output: AT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the compound most bound to?. ### Response: AT.


Instruction: How long does the compound last after it is almost complete bioavailability?

Output: 25 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does the compound last after it is almost complete bioavailability?. ### Response: 25 h.


Instruction: What is the name of the guideline for secondary prevention and risk reduction therapy for patients with coronary andother atherosclerotic vascular disease?

Output: AHA/ACCF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for secondary prevention and risk reduction therapy for patients with coronary andother atherosclerotic vascular disease?. ### Response: AHA/ACCF.


Instruction: What year was the ACCF/AHA/ACCF updated?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the ACCF/AHA/ACCF updated?. ### Response: 2011.


Instruction: What is the 2011 ACCF/AHA guideline for coronary artery bypass graft surgery?

Output: a report of the AmericanCollege of Cardiology Foundation/American Heart Association TaskForce on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2011 ACCF/AHA guideline for coronary artery bypass graft surgery?. ### Response: a report of the AmericanCollege of Cardiology Foundation/American Heart Association TaskForce on Practice Guidelines.


Instruction: What is a report of the AmericanCollege of Cardiology Foundation/American Heart Association Taskforce on Practice Guidelines?

Output: coronary artery bypass graft surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the AmericanCollege of Cardiology Foundation/American Heart Association Taskforce on Practice Guidelines?. ### Response: coronary artery bypass graft surgery.


Instruction: What is the 2011 ACCF/AHA/S CAIguideline for percutaneous coronary intervention?

Output: a repor t of the AmericanCollege of Cardiology Foundation/American Heart Associat ion TaskForce on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2011 ACCF/AHA/S CAIguideline for percutaneous coronary intervention?. ### Response: a repor t of the AmericanCollege of Cardiology Foundation/American Heart Associat ion TaskForce on Practice Guidelines.


Instruction: What is a report of the AmericanCollege of Cardiology Foundation/American Heart Associat ion TaskForce on Practice Guidelines and the Society for CardiovascularAngiography and Interventions?

Output: 2011 ACCF/AHA/S CAIguideline for percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the AmericanCollege of Cardiology Foundation/American Heart Associat ion TaskForce on Practice Guidelines and the Society for CardiovascularAngiography and Interventions?. ### Response: 2011 ACCF/AHA/S CAIguideline for percutaneous coronary intervention.


Instruction: What is the ACCF's proposed method for evaluating the appropriateness of cardiovascular imaging?

Output: Appropriate Use Criteria Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACCF's proposed method for evaluating the appropriateness of cardiovascular imaging?. ### Response: Appropriate Use Criteria Task Force.


Instruction: When was the J Am CollCardiol 46:1606–13.12?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am CollCardiol 46:1606–13.12?. ### Response: 2005.


Instruction: What is a report of the American College of CardiologyFoundation Appropriate Use Criteria Task Force?

Output: 2010 appropriate use criteria f orcardiac computed tomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of CardiologyFoundation Appropriate Use Criteria Task Force?. ### Response: 2010 appropriate use criteria f orcardiac computed tomography.


Instruction: What is the acronym for CardiologyFoundation Appropriate Use Criteria Task Force?

Output: QualityStrategic Directions Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for CardiologyFoundation Appropriate Use Criteria Task Force?. ### Response: QualityStrategic Directions Committee.


Instruction: What is another acronym for American Heart Association?

Output: AmericanCollege of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another acronym for American Heart Association?. ### Response: AmericanCollege of Cardiology Foundation.


Instruction: The American Society of Echocardiogra-phy, the Society of Cardiovascular Computed Tomography, and the Society for Cardiovascular Magnetic Resonance are examples of what?

Output: a report of the American College ofCardiology Foundation Appropriate Use Criteria Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The American Society of Echocardiogra-phy, the Society of Cardiovascular Computed Tomography, and the Society for Cardiovascular Magnetic Resonance are examples of what?. ### Response: a report of the American College ofCardiology Foundation Appropriate Use Criteria Task Force.


Instruction: NuclearMedicine. 2009;119:e561–87.13 What is the 2006 appropriateness criteria for ca rdiaccomputed tomography and cardiac magnetic resonance imaging?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: NuclearMedicine. 2009;119:e561–87.13 What is the 2006 appropriateness criteria for ca rdiaccomputed tomography and cardiac magnetic resonance imaging?. ### Response: 2006.


Instruction: What is the American Society of Nuclear Cardiology?

Output: Society for Cardiovascular Magnetic Res-onance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the American Society of Nuclear Cardiology?. ### Response: Society for Cardiovascular Magnetic Res-onance.


Instruction: What is another name for North American Society for Cardiac Imaging?

Output: Car-diovascular Imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for North American Society for Cardiac Imaging?. ### Response: Car-diovascular Imaging.


Instruction: When was the J Am CollCardiol 48:1475-97.14?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am CollCardiol 48:1475-97.14?. ### Response: 2006.


Instruction: What is the name of the group that compiled a report on appropriate use criteria for computed tomography?

Output: American College ofCardiology Foundation Appropriate Use Criteria Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that compiled a report on appropriate use criteria for computed tomography?. ### Response: American College ofCardiology Foundation Appropriate Use Criteria Task Force.


Instruction: What does the Society of Cardiovascular Computed Tomography do?

Output: a report of the American College ofCardiology Foundation Appropriate Use Criteria Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Society of Cardiovascular Computed Tomography do?. ### Response: a report of the American College ofCardiology Foundation Appropriate Use Criteria Task Force.


Instruction: Who is the American Society for Nuclear Cardiology?

Output: American College of CardiologyFoundation Appropriate Use Criteria Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the American Society for Nuclear Cardiology?. ### Response: American College of CardiologyFoundation Appropriate Use Criteria Task Force.


Instruction: The American Society of Nuclear Cardiology, the North American Society for Car-diovascular Imaging, the Society for Cardiovascular Angiography and Interventions and the Society For Cardiovascular Magnetic Resonance are examples of what?

Output: a report of the American College ofCardiology Foundation Appropriate Use Criteria Task Force ,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The American Society of Nuclear Cardiology, the North American Society for Car-diovascular Imaging, the Society for Cardiovascular Angiography and Interventions and the Society For Cardiovascular Magnetic Resonance are examples of what?. ### Response: a report of the American College ofCardiology Foundation Appropriate Use Criteria Task Force ,.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 7 of 134 II?

Output: an update to the 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 7 of 134 II?. ### Response: an update to the 2014.


Instruction: Under what auspices was this guideline developed?

Output: VHA and the  DoD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Under what auspices was this guideline developed?. ### Response: VHA and the  DoD.


Instruction: DoD pursuant to directives from the VA is an update to the 2014 VA/DoD Clinical Practice Guideline for Diagnosis and Management of Hypertension in the Primary Care Setting?

Output: Evidence Based Guideline for the Management of High Blood Pressure in Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: DoD pursuant to directives from the VA is an update to the 2014 VA/DoD Clinical Practice Guideline for Diagnosis and Management of Hypertension in the Primary Care Setting?. ### Response: Evidence Based Guideline for the Management of High Blood Pressure in Adults.


Instruction: The definition of HTN continues to evolve and an international consensus does not exist what?

Output: proven for lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The definition of HTN continues to evolve and an international consensus does not exist what?. ### Response: proven for lowering.


Instruction: When was the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure published?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure published?. ### Response: 2003.


Instruction: What did JNC 7 define as a systolic blood pressure 140 mm Hg?

Output: SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did JNC 7 define as a systolic blood pressure 140 mm Hg?. ### Response: SBP.


Instruction: What is a diastolic blood pressure  90 mm Hg?

Output: DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a diastolic blood pressure  90 mm Hg?. ### Response: DBP.


Instruction: What did the 2014 Evidence Based Guideline for the Management of High Blood Pressure in Adults not change?

Output: HTN as  a systolic blood pressure (SBP) ≥140 mm Hg or a diastolic blood pressure (DBP) ≥ 90 mm Hg. This definition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2014 Evidence Based Guideline for the Management of High Blood Pressure in Adults not change?. ### Response: HTN as  a systolic blood pressure (SBP) ≥140 mm Hg or a diastolic blood pressure (DBP) ≥ 90 mm Hg. This definition.


Instruction: Prehypertension was classified as SBP 120 -139 or what?

Output: DBP 80- 89

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prehypertension was classified as SBP 120 -139 or what?. ### Response: DBP 80- 89.


Instruction: Who defines HTN as an SBP  130 mm Hg?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who defines HTN as an SBP  130 mm Hg?. ### Response: American College of Cardiology/American Heart Association.


Instruction: What was removed as a clinical term?

Output: Prehypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was removed as a clinical term?. ### Response: Prehypertension.


Instruction: How was elevated blood pressure defined?

Output: an SBP of 120 -129 with a DBP <80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was elevated blood pressure defined?. ### Response: an SBP of 120 -129 with a DBP <80 mm Hg.


Instruction: What pressure was added and defined as an SBP of 120 -129 with a DBP 80 mm Hg?

Output: elevated blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What pressure was added and defined as an SBP of 120 -129 with a DBP 80 mm Hg?. ### Response: elevated blood pressure.


Instruction: For the purposes of this CPG, the Work Group defines HTN as what?

Output: SBP and/or DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For the purposes of this CPG, the Work Group defines HTN as what?. ### Response: SBP and/or DBP.


Instruction: What is a DBP 90 mm Hg?

Output: diastolic blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a DBP 90 mm Hg?. ### Response: diastolic blood pressure.


Instruction: What is the reason for the evolution over time in the definition of HTN?

Output: the evidence base supporting the benefits of treatment continue to change

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reason for the evolution over time in the definition of HTN?. ### Response: the evidence base supporting the benefits of treatment continue to change.


Instruction: Why does the evidence base supporting the benefits of treatment continue to change?

Output: The reason for the evolution over time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why does the evidence base supporting the benefits of treatment continue to change?. ### Response: The reason for the evolution over time.


Instruction: What is the relationship between systemic arterial pressure and cardiovascular morbidity or mortality based on epidemiologic data?

Output: linear above 115/75 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between systemic arterial pressure and cardiovascular morbidity or mortality based on epidemiologic data?. ### Response: linear above 115/75 mm Hg.


Instruction: The evidence supporting benefit from treatment of elevated blood pressure starts at what threshold?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The evidence supporting benefit from treatment of elevated blood pressure starts at what threshold?. ### Response: higher.


Instruction: Kaplan and Victor suggest the definition of what?

Output: HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kaplan and Victor suggest the definition of what?. ### Response: HTN.


Instruction: What does Kaplan and Victor say should be the point at which the benefit of treatment of elevated blood pressure outweighs the risks and cost?

Output: HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Kaplan and Victor say should be the point at which the benefit of treatment of elevated blood pressure outweighs the risks and cost?. ### Response: HTN.


Instruction: Treatment of HTN has long been associated with what?

Output: benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Treatment of HTN has long been associated with what?. ### Response: benefit.


Instruction: What has not been proven for lowering blood pressure?

Output: Treatment of HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been proven for lowering blood pressure?. ### Response: Treatment of HTN.


Instruction: What has not been proven for lowering slightly elevated blood pressures to a normal blood pressure of 115/75 mm Hg?

Output: Treatment of HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been proven for lowering slightly elevated blood pressures to a normal blood pressure of 115/75 mm Hg?. ### Response: Treatment of HTN.


Instruction: What did the Work Group specifically investigate the point of proven benefit for for HTN treatment?

Output: CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group specifically investigate the point of proven benefit for for HTN treatment?. ### Response: CPG.


Instruction: What does the Work Group define as SBP and/or DBP at or above 130/90 mm Hg?

Output: HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Work Group define as SBP and/or DBP at or above 130/90 mm Hg?. ### Response: HTN.


Instruction: There is no evidence to date that there is a benefit from what?

Output: For those with a blood pressure above “normal” but not in the hypertensive range, there is no evidence to date that there is a benefit from treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no evidence to date that there is a benefit from what?. ### Response: For those with a blood pressure above “normal” but not in the hypertensive range, there is no evidence to date that there is a benefit from treatment.


Instruction: However, their cardiovascular risk remains elevated?

Output: For those with a blood pressure above “normal” but not in the hypertensive range, there is no evidence to date that there is a benefit from treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: However, their cardiovascular risk remains elevated?. ### Response: For those with a blood pressure above “normal” but not in the hypertensive range, there is no evidence to date that there is a benefit from treatment.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseFebruary 2, 2021 Circulation. 2021;143:e72–e227

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseFebruary 2, 2021 Circulation. 2021;143:e72–e227.


Instruction: When was the 2020 AHA/ACC guideline published?

Output: February 2, 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2020 AHA/ACC guideline published?. ### Response: February 2, 2021.


Instruction: What are the 5-Year outcomes of self-expanding transcatheter versus surgical aortic valve replacement in high-risk patients?

Output: 2018;72:2687–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 5-Year outcomes of self-expanding transcatheter versus surgical aortic valve replacement in high-risk patients?. ### Response: 2018;72:2687–.


Instruction: What is the risk factor for aortic valve replacement in high-risk patients?

Output: lifetime anticoagulant-related event risk against reopera-tion risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk factor for aortic valve replacement in high-risk patients?. ### Response: lifetime anticoagulant-related event risk against reopera-tion risk.


Instruction: What does Blackman DJ, Saraf S, MacCarthy PA, et al. have to say about trans-catheter prostheses?

Output: Long-term durability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Blackman DJ, Saraf S, MacCarthy PA, et al. have to say about trans-catheter prostheses?. ### Response: Long-term durability.


Instruction: What is the difference between mechanical and mechanical prostheses for aortic valve and mitral valve replacement?

Output: improved outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between mechanical and mechanical prostheses for aortic valve and mitral valve replacement?. ### Response: improved outcome.


Instruction: What are the benefits of surgical bioprosthetics for patients at lower surgical risk?

Output: Durability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the benefits of surgical bioprosthetics for patients at lower surgical risk?. ### Response: Durability.


Instruction: What type of prostheses can be used for aortic-valve replacement?

Output: bioprosthetic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of prostheses can be used for aortic-valve replacement?. ### Response: bioprosthetic.


Instruction: What year did N Engl J Med issue 377:1847-57?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med issue 377:1847-57?. ### Response: 2017.


Instruction: Why is noninferiority of closely moni-tored mechanical valves overshadowed by early mortality benefit in younger patients?

Output: bioprostheses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is noninferiority of closely moni-tored mechanical valves overshadowed by early mortality benefit in younger patients?. ### Response: bioprostheses.


Instruction: What year did Surg. 2012:93:748–53?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Surg. 2012:93:748–53?. ### Response: 2012.


Instruction: What year was Surg Surg?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Surg Surg?. ### Response: 2008.


Instruction: How old were the patients who received aortic valve replacement?

Output: 50 to 70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old were the patients who received aortic valve replacement?. ### Response: 50 to 70 years.


Instruction: What did Kappetein AP and Lam B-K weigh against reoperation risk?

Output: lifetime anticoagulant-related event risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Kappetein AP and Lam B-K weigh against reoperation risk?. ### Response: lifetime anticoagulant-related event risk.


Instruction: What was the J Thorac Cardiovasc Surg. 2009;137:881–6, 866.e1–5?

Output: Aortic valve replacement in patients aged 50 to 70 years: improved outcome with mechanical versus biologic prostheses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Thorac Cardiovasc Surg. 2009;137:881–6, 866.e1–5?. ### Response: Aortic valve replacement in patients aged 50 to 70 years: improved outcome with mechanical versus biologic prostheses.


Instruction: What is the difference between mechanical versus bioprosthetic valve replacement in middle-aged patients?

Output: improved outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between mechanical versus bioprosthetic valve replacement in middle-aged patients?. ### Response: improved outcome.


Instruction: What year did Eur J Cardiothorac Surg.30:485–91?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Eur J Cardiothorac Surg.30:485–91?. ### Response: 2006.


Instruction: How old are patients with aortic valve replacements?

Output: 50 to 70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are patients with aortic valve replacements?. ### Response: 50 to 70 years.


Instruction: What is the age range of patients who undergo a bioprosthetic vs mechanical mitral valve replacement?

Output: 50 to 69 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age range of patients who undergo a bioprosthetic vs mechanical mitral valve replacement?. ### Response: 50 to 69 years.


Instruction: When did the JAMA issue 313:1435-42?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the JAMA issue 313:1435-42?. ### Response: 2015.


Instruction: What was the name of the study that compared the late outcomes of nonelderly patients with stented biopropsthetic and mechanical valves?

Output: J Thorac Cardiovasc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that compared the late outcomes of nonelderly patients with stented biopropsthetic and mechanical valves?. ### Response: J Thorac Cardiovasc.


Instruction: What is a propensity-matched analysis of nonelderly patients with stented bioprosthetic and mechanical valves in the aortic position?

Output: Late outcomes comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a propensity-matched analysis of nonelderly patients with stented bioprosthetic and mechanical valves in the aortic position?. ### Response: Late outcomes comparison.


Instruction: What is the name of the study that compares the survival and long-term out-comes following a prosthetic vs mechanical Aortic valve replacement in patients aged 50 to 69 years?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares the survival and long-term out-comes following a prosthetic vs mechanical Aortic valve replacement in patients aged 50 to 69 years?. ### Response: JAMA.


Instruction: What is the age range for aortic valve replacement in patients?

Output: 50 to 70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age range for aortic valve replacement in patients?. ### Response: 50 to 70 years.


Instruction: How old are patients with mitral valve replacement?

Output: 50 to 69 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are patients with mitral valve replacement?. ### Response: 50 to 69 years.


Instruction: What are the benefits of mechanical versus bioprosthetic valve replacements?

Output: improved outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the benefits of mechanical versus bioprosthetic valve replacements?. ### Response: improved outcome.


Instruction: What is the Carpentier-Edwards pericardial bio-marker used for?

Output: mitral valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Carpentier-Edwards pericardial bio-marker used for?. ### Response: mitral valve replacement.


Instruction: What is the DOI for 2019 AHA/ACC High Blood Pressure Performance and Quality MeasuresCirc Cardiovasc Qual Outcomes?

Output: 12:e000057

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI for 2019 AHA/ACC High Blood Pressure Performance and Quality MeasuresCirc Cardiovasc Qual Outcomes?. ### Response: 12:e000057.


Instruction: What is the percentage of Adults 18 to 85 years of age who had a Diagnosis of ACC/AHA Stage 1 HBP With ASCVD Risk 10%?

Output: ≥10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of Adults 18 to 85 years of age who had a Diagnosis of ACC/AHA Stage 1 HBP With ASCVD Risk 10%?. ### Response: ≥10%.


Instruction: What was the percentage of Adherence to BP Medication(s) during the Measurement Year?

Output: ≥80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the percentage of Adherence to BP Medication(s) during the Measurement Year?. ### Response: ≥80%.


Instruction: What percentage of patients with ACC/AHA stage 1 HBP and ASCVD risk had 80% adherence to prescribed BP medication(s) during the measurement year?

Output: ≥10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with ACC/AHA stage 1 HBP and ASCVD risk had 80% adherence to prescribed BP medication(s) during the measurement year?. ### Response: ≥10%.


Instruction: Patients with 1 prescriptions for BP medications who met the PDC threshold met what threshold?

Output: ≥80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with 1 prescriptions for BP medications who met the PDC threshold met what threshold?. ### Response: ≥80%.


Instruction: Who met the PDC threshold of 80% during the measurement year?

Output: Numerator Patients with ≥1 prescriptions for BP medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who met the PDC threshold of 80% during the measurement year?. ### Response: Numerator Patients with ≥1 prescriptions for BP medication.


Instruction: All patients 18-85 y of age with ACC/AHA stage 1 HBP and ASCVD risk 10% or who had at least 1 outpatient encounter with a diagnosis of HBP?

Output: 10.1161/HCQ.0000000000000057 November 2019 29Appendix A. ContinuedShort Title: QM-4: Medication Adherence to Drug Therapy for ACC/AHA Stage 1 With ASCVD Risk ≥10% or ACC/AHA Stage 2 HBPQM-4: Percentage of Adults 18 to 85 Years of Age Who Had a Diagnosis of ACC/AHA Stage 1 HBP With ASCVD Risk ≥10% or ACC/AHA Stage 2 HBP With ≥1 Prescriptions for BP Medication Who Had ≥80% Adherence to BP Medication(s) During the Measurement Year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: All patients 18-85 y of age with ACC/AHA stage 1 HBP and ASCVD risk 10% or who had at least 1 outpatient encounter with a diagnosis of HBP?. ### Response: 10.1161/HCQ.0000000000000057 November 2019 29Appendix A. ContinuedShort Title: QM-4: Medication Adherence to Drug Therapy for ACC/AHA Stage 1 With ASCVD Risk ≥10% or ACC/AHA Stage 2 HBPQM-4: Percentage of Adults 18 to 85 Years of Age Who Had a Diagnosis of ACC/AHA Stage 1 HBP With ASCVD Risk ≥10% or ACC/AHA Stage 2 HBP With ≥1 Prescriptions for BP Medication Who Had ≥80% Adherence to BP Medication(s) During the Measurement Year.


Instruction: How many prescriptions for BP medications did a patient have during the first 6 mo of the measurement year?

Output: ≥1 or more

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prescriptions for BP medications did a patient have during the first 6 mo of the measurement year?. ### Response: ≥1 or more.


Instruction: What are the nonnominator exclusions of end-stage renal disease, kidney transplantation, pregnancy?

Output: patients solely on nonpharmacological therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the nonnominator exclusions of end-stage renal disease, kidney transplantation, pregnancy?. ### Response: patients solely on nonpharmacological therapy.


Instruction: What type of readings are taken during an inpatient stay?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of readings are taken during an inpatient stay?. ### Response: BP.


Instruction: What is a medical reason for documenting an exception?

Output: treatment intolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a medical reason for documenting an exception?. ### Response: treatment intolerance.


Instruction: How long is the measurement period?

Output: 12 mo/measurement year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the measurement period?. ### Response: 12 mo/measurement year.


Instruction: How long does it take for drug therapy to be effective?

Output: ≥10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for drug therapy to be effective?. ### Response: ≥10%.


Instruction: What type of data does Tricare collect?

Output: claims data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of data does Tricare collect?. ### Response: claims data.


Instruction: How does drug therapy affect BP?

Output: lowers BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does drug therapy affect BP?. ### Response: lowers BP.


Instruction: What lowers BP and reduces the risk of cardiovascular events and death?

Output: Adherence to drug therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What lowers BP and reduces the risk of cardiovascular events and death?. ### Response: Adherence to drug therapy.


Instruction: What percentage of patients prescribed antihypertensive medications demonstrate suboptimal adherence?

Output: 50% to 80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients prescribed antihypertensive medications demonstrate suboptimal adherence?. ### Response: 50% to 80%.


Instruction: Adherence to drug therapy is influenced by large pill burden, complex drug regimen, cost of medications, and what other factor?

Output: clinical inertia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adherence to drug therapy is influenced by large pill burden, complex drug regimen, cost of medications, and what other factor?. ### Response: clinical inertia.


Instruction: What has been found to be more effective than others in improving adherence?

Output: No single strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been found to be more effective than others in improving adherence?. ### Response: No single strategy.


Instruction: What is a combination of patient-level, provider-level and system-level strategies likely to do?

Output: improving adherence, but rather, a combination of patient-level, provider-level, and system-level strategies is likely to be the most effective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a combination of patient-level, provider-level and system-level strategies likely to do?. ### Response: improving adherence, but rather, a combination of patient-level, provider-level, and system-level strategies is likely to be the most effective.


Instruction: What strategies are likely to be the most effective?

Output: patient-level, provider-level, and system-level strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What strategies are likely to be the most effective?. ### Response: patient-level, provider-level, and system-level strategies.


Instruction: Medication adherence is highest with once-daily dosing and declines within increasing how often?

Output: dosing frequency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Medication adherence is highest with once-daily dosing and declines within increasing how often?. ### Response: dosing frequency.


Instruction: The Hill-Bone Compliance to HBP Therapy Scale can be used to identify barriers to what?

Output: medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Hill-Bone Compliance to HBP Therapy Scale can be used to identify barriers to what?. ### Response: medication.


Instruction: Exercise or stress agents are used to increase myocardialwork and what else?

Output: oxygen demand

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise or stress agents are used to increase myocardialwork and what else?. ### Response: oxygen demand.


Instruction: Exercise is used to induce vasodilation-elicitedheterogeneity in what?

Output: induced coronary flow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise is used to induce vasodilation-elicitedheterogeneity in what?. ### Response: induced coronary flow.


Instruction: What type of toxicity is associated with pheochromocytoma?

Output: Sympathomimetic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of toxicity is associated with pheochromocytoma?. ### Response: Sympathomimetic.


Instruction: What is a symptom of CAD in symptomatic patients according to age and sex?

Output: coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a symptom of CAD in symptomatic patients according to age and sex?. ### Response: coronary artery disease.


Instruction: What does Combined Diamond/Forrester andCASS Data indicate?

Output: CAD in Symptomatic Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Combined Diamond/Forrester andCASS Data indicate?. ### Response: CAD in Symptomatic Patients.