Instruction: What is the current British Thoracic Society guideline s (2015)142.for home oxygen?

Output: only hypoxaemic patients with PO2 below 7.3kpa or 8 (with peripheral oedema, polycythaemi a or pulmonary hypertension) should receive any form of home oxygen therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current British Thoracic Society guideline s (2015)142.for home oxygen?. ### Response: only hypoxaemic patients with PO2 below 7.3kpa or 8 (with peripheral oedema, polycythaemi a or pulmonary hypertension) should receive any form of home oxygen therapy.


Instruction: Who should receive home oxygen therapy except for a specific group with sleep disordered breathing?

Output: hypoxaemic patients with PO2 below 7.3kpa or 8 (with peripheral oedema, polycythaemi a or pulmonary hypertension)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should receive home oxygen therapy except for a specific group with sleep disordered breathing?. ### Response: hypoxaemic patients with PO2 below 7.3kpa or 8 (with peripheral oedema, polycythaemi a or pulmonary hypertension).


Instruction: What is a specific group with sleep disordered breathing?

Output: COPD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a specific group with sleep disordered breathing?. ### Response: COPD.


Instruction: What is the evidence base for these recommendations?

Output: limited

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the evidence base for these recommendations?. ### Response: limited.


Instruction: An up-to-date review of what is warranted?

Output: the literature in this area

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: An up-to-date review of what is warranted?. ### Response: the literature in this area.


Instruction: What is the effectiveness of domiciliary oxygen therapy in people with advanced heart fa ilure?

Output: daily availability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effectiveness of domiciliary oxygen therapy in people with advanced heart fa ilure?. ### Response: daily availability.


Instruction: What are the characteristics of the review question?

Output: Review population  Adults (aged 18 years and over) with advanced heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the characteristics of the review question?. ### Response: Review population  Adults (aged 18 years and over) with advanced heart failure.


Instruction: What are the PICO characteristics of review population Adults (aged 18 years and over) with advanced heart failure?

Output: Table 142

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the PICO characteristics of review population Adults (aged 18 years and over) with advanced heart failure?. ### Response: Table 142.


Instruction: What is the term for a c are home?

Output: c ommunity res idential facility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for a c are home?. ### Response: c ommunity res idential facility.


Instruction: What type of patients may be approaching the end of their life and may be receiving other palliative care services?

Output: Adults (aged 18 years and over) with advanced heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients may be approaching the end of their life and may be receiving other palliative care services?. ### Response: Adults (aged 18 years and over) with advanced heart failure.


Instruction: What are patients with heart failure and other co-morbidities included in?

Output: Trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with heart failure and other co-morbidities included in?. ### Response: Trials.


Instruction: What type of oxygen therapy is used for repeated long term use?

Output: Domiciliary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of oxygen therapy is used for repeated long term use?. ### Response: Domiciliary.


Instruction: What is another name for Domiciliary oxygen therapy?

Output: repeated long term use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Domiciliary oxygen therapy?. ### Response: repeated long term use.


Instruction: How many doses of oxygen will be pooled in the analysis?

Output: Different doses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many doses of oxygen will be pooled in the analysis?. ### Response: Different doses.


Instruction: What will be pooled in the analysis?

Output: Different doses of oxygen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will be pooled in the analysis?. ### Response: Different doses of oxygen.


Instruction: What are the Outcomes CRITICIAL?

Output: Quality of life at 2 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Outcomes CRITICIAL?. ### Response: Quality of life at 2 weeks.


Instruction: How long is the Quality of life at 2 weeks?

Output: Continuous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the Quality of life at 2 weeks?. ### Response: Continuous.


Instruction: How long is an unplanned hospitalization?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is an unplanned hospitalization?. ### Response: 4 weeks.


Instruction: What is the number of bed days?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the number of bed days?. ### Response: 4 weeks.


Instruction: How much satisfaction does the patient and carer have?

Output: 2 wee ks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much satisfaction does the patient and carer have?. ### Response: 2 wee ks.


Instruction: Who published the 2019 Guidelines for Management of AIS e417 455?

Output: Powers et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 Guidelines for Management of AIS e417 455?. ### Response: Powers et al.


Instruction: What is the name of the meta-analysis that evaluated the efficacy and safety of citalopram in treating post stroke depression?

Output: Powers et al  2019 Guidelines for Management of AIS  e417 485. Tan S, Huang X, Ding L, Hong H. Efficacy and safety of citalopram in treating post-stroke depression: a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis that evaluated the efficacy and safety of citalopram in treating post stroke depression?. ### Response: Powers et al  2019 Guidelines for Management of AIS  e417 485. Tan S, Huang X, Ding L, Hong H. Efficacy and safety of citalopram in treating post-stroke depression: a meta-analysis.


Instruction: What is the name of the randomized controlled trial of early sitting in ischemic stroke patients?

Output: SEVEL Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial of early sitting in ischemic stroke patients?. ### Response: SEVEL Study Group.


Instruction: What study was conducted by the SEVEL Study Group?

Output: Early Sitting in Ischemic Stroke Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study was conducted by the SEVEL Study Group?. ### Response: Early Sitting in Ischemic Stroke Patients.


Instruction: What is the name of the randomized controlled trial of SEVEL?

Output: SEVEL Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial of SEVEL?. ### Response: SEVEL Study Group.


Instruction: When did SEVEL take place?

Output: Early Sitting in Ischemic Stroke Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did SEVEL take place?. ### Response: Early Sitting in Ischemic Stroke Patients.


Instruction: What is a proprioceptive or cognitive approach in stroke patients?

Output: Early versus delayed rehabilitation treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a proprioceptive or cognitive approach in stroke patients?. ### Response: Early versus delayed rehabilitation treatment.


Instruction: What does Eur J Phys Rehabil Med. 2016:52:81–89?

Output: cognitive approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Eur J Phys Rehabil Med. 2016:52:81–89?. ### Response: cognitive approach.


Instruction: What is the cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack?

Output: Cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack. Med Decis Making. 2007;27:161–177

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack?. ### Response: Cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack. Med Decis Making. 2007;27:161–177.


Instruction: What is a cost-effectiveness analysis for stroke management?

Output: Echocardiographic identification of cardiovascular sources of emboli

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cost-effectiveness analysis for stroke management?. ### Response: Echocardiographic identification of cardiovascular sources of emboli.


Instruction: What is the name of the study that identified cardiovascular sources of emboli to guide clinical management of stroke?

Output: Echocardiographic identification of cardiovascular sources of emboli to guide clinical management of stroke: a cost-effectiveness analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that identified cardiovascular sources of emboli to guide clinical management of stroke?. ### Response: Echocardiographic identification of cardiovascular sources of emboli to guide clinical management of stroke: a cost-effectiveness analysis.


Instruction: How many strokes were there in 2007?

Output: 27:161

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 2007?. ### Response: 27:161.


Instruction: Med. 1997;127:775–787. doi: 10.7326/0003-4819-127-9-199711010-00001 491. Shariat A, Yaghoubi E, Farazdaghi M, Aghasadeghi K, Borhani Haghighi A. Comparison of medical treatments in cryptogenic stroke patients with patent foramen ovale: a randomized clinical trial?

Output: Ann Intern

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Med. 1997;127:775–787. doi: 10.7326/0003-4819-127-9-199711010-00001 491. Shariat A, Yaghoubi E, Farazdaghi M, Aghasadeghi K, Borhani Haghighi A. Comparison of medical treatments in cryptogenic stroke patients with patent foramen ovale: a randomized clinical trial?. ### Response: Ann Intern.


Instruction: What is the name of the PICSS Investigators?

Output: PFO in Cryptogenic Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PICSS Investigators?. ### Response: PFO in Cryptogenic Stroke Study.


Instruction: What is one of the effects of medical treatment in stroke patients with patent foramen ovale?

Output: Patent Foramen Ovale in Cryptogenic Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the effects of medical treatment in stroke patients with patent foramen ovale?. ### Response: Patent Foramen Ovale in Cryptogenic Stroke Study.


Instruction: What does Patent foramen ovale closure or medical therapy for secondary pre-vention of cryptogenic stroke do?

Output: an update meta-analysis of random-ized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Patent foramen ovale closure or medical therapy for secondary pre-vention of cryptogenic stroke do?. ### Response: an update meta-analysis of random-ized controlled trials.


Instruction: What is the doi: 10.1097/MD.0000000000011965?

Output: 494

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1097/MD.0000000000011965?. ### Response: 494.


Instruction: What is the name of the meta-analysis of randomized controlled trials?

Output: amen ovale closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of randomized controlled trials?. ### Response: amen ovale closure.


Instruction: What is another name for medical therapy for cryptogenic ischemic stroke?

Output: amen ovale closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for medical therapy for cryptogenic ischemic stroke?. ### Response: amen ovale closure.


Instruction: What does Clin Res Cardiol 107:745-755 say about secondary prevention of cryptogenic stroke?

Output: Patent foramen ovale closure or medical therapy for secondary pre-vention of cryptogenic stroke: an update meta-analysis of random-ized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Clin Res Cardiol 107:745-755 say about secondary prevention of cryptogenic stroke?. ### Response: Patent foramen ovale closure or medical therapy for secondary pre-vention of cryptogenic stroke: an update meta-analysis of random-ized controlled trials.


Instruction: In patients with patent foramen ovale: a systematic review and meta-analysis?

Output: Secondary prevention of cryptogenic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with patent foramen ovale: a systematic review and meta-analysis?. ### Response: Secondary prevention of cryptogenic stroke.


Instruction: Intern Emerg Med. 2018;13:1287-1303. doi: 10.1007/s11739-018-1909-8.

Output: amen ovale closure or medical therapy for cryptogenic ischemic stroke: an updated meta-analysis of randomized controlled trials. Clin Res Cardiol. 2018;107:745–755. doi: 10.1007/s00392-018-1224-4 495. Fiorelli EM, Carandini T, Gagliardi D, Bozzano V , Bonzi M, Tobaldini E, Comi GP, Scarpini EA, Montano N, Solbiati M. Secondary prevention of cryptogenic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Intern Emerg Med. 2018;13:1287-1303. doi: 10.1007/s11739-018-1909-8.. ### Response: amen ovale closure or medical therapy for cryptogenic ischemic stroke: an updated meta-analysis of randomized controlled trials. Clin Res Cardiol. 2018;107:745–755. doi: 10.1007/s00392-018-1224-4 495. Fiorelli EM, Carandini T, Gagliardi D, Bozzano V , Bonzi M, Tobaldini E, Comi GP, Scarpini EA, Montano N, Solbiati M. Secondary prevention of cryptogenic stroke.


Instruction: What is NICE 2018's approach to care for Chronic Heart Failure?

Output: All rights reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018's approach to care for Chronic Heart Failure?. ### Response: All rights reserved.


Instruction: What is the ISBN 978-1-4731 -3093-7 378 Subject to Notice of rights?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ISBN 978-1-4731 -3093-7 378 Subject to Notice of rights?. ### Response: Chronic Heart Failure.


Instruction: Rating Overall assessment of confidence 3a Poor communication between services 6 29, 47, 126, 133, 144, 207 Focus group with HCP in care homes Interviews with pt with advanced CHF and their care network What is the rating?

Output: 2 202

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Rating Overall assessment of confidence 3a Poor communication between services 6 29, 47, 126, 133, 144, 207 Focus group with HCP in care homes Interviews with pt with advanced CHF and their care network What is the rating?. ### Response: 2 202.


Instruction: Who felt that there was poor communication across boundaries?

Output: People with heart  failure, their informal carers and professionals within and outside HF services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who felt that there was poor communication across boundaries?. ### Response: People with heart  failure, their informal carers and professionals within and outside HF services.


Instruction: Who felt poor communication affected patient experience and patient care?

Output: People with heart  failure, their informal carers and professionals within and outside HF services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who felt poor communication affected patient experience and patient care?. ### Response: People with heart  failure, their informal carers and professionals within and outside HF services.


Instruction: What is one of the major limitations of the methodology?

Output: Coherence  no or very minor concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the major limitations of the methodology?. ### Response: Coherence  no or very minor concerns.


Instruction: What is another limitation of the methodology?

Output: Coherence  no or very minor concerns  Relevance  no or very minor concerns  Adequacy  no or very minor concerns  3b Barriers to clear communication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another limitation of the methodology?. ### Response: Coherence  no or very minor concerns  Relevance  no or very minor concerns  Adequacy  no or very minor concerns  3b Barriers to clear communication.


Instruction: How many interviews were conducted with HCPs?

Output: 2 202, 209

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many interviews were conducted with HCPs?. ### Response: 2 202, 209.


Instruction: Interviews of HCP in HF care Questionnaire to HCP Healthcare professionals felt that some barriers to cross -boundary communication were what?

Output: fragmented and incompatible inform ation systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Interviews of HCP in HF care Questionnaire to HCP Healthcare professionals felt that some barriers to cross -boundary communication were what?. ### Response: fragmented and incompatible inform ation systems.


Instruction: How many interviews with pt People with heart failure experience being interviewed?

Output: 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many interviews with pt People with heart failure experience being interviewed?. ### Response: 14.


Instruction: What type of concerns are there?

Output: serious concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of concerns are there?. ### Response: serious concerns.


Instruction: How many interviews with pt People with heart failure experience being well-informed in HF clinic but receiving no information after being discharged to primary care?

Output: 1 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many interviews with pt People with heart failure experience being well-informed in HF clinic but receiving no information after being discharged to primary care?. ### Response: 1 14.


Instruction: What did some people take as a sign they no longer needed care for their heart failure?

Output: no information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some people take as a sign they no longer needed care for their heart failure?. ### Response: no information.


Instruction: What serious limitations are there?

Output: Methodology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What serious limitations are there?. ### Response: Methodology.


Instruction: What serious concerns are there about the methodology?

Output: Adequacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What serious concerns are there about the methodology?. ### Response: Adequacy.


Instruction: What does isradipine(Lomir) do after kidney transplantation?

Output: better renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does isradipine(Lomir) do after kidney transplantation?. ### Response: better renal function.


Instruction: What is the effect of diltiazem on acute kidney failure?

Output: Protective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of diltiazem on acute kidney failure?. ### Response: Protective.


Instruction: What is the calciumantagonist of diltiazem used for?

Output: acute kidney failure following kidneytransplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the calciumantagonist of diltiazem used for?. ### Response: acute kidney failure following kidneytransplantation.


Instruction: What was the result of a prospective randomized study?

Output: Protective effect of the calciumantagonist diltiazem on acute kidney failure following kidneytransplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of a prospective randomized study?. ### Response: Protective effect of the calciumantagonist diltiazem on acute kidney failure following kidneytransplantation.


Instruction: When was the 111th DtschMed Wochenschr published?

Output: 1986

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 111th DtschMed Wochenschr published?. ### Response: 1986.


Instruction: What is nifedipine used for in kidney transplant recipients?

Output: early renal allograft function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is nifedipine used for in kidney transplant recipients?. ### Response: early renal allograft function.


Instruction: What is angiotensin II blockade?

Output: inkidney transplant recipients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is angiotensin II blockade?. ### Response: inkidney transplant recipients.


Instruction: How does angiotensin II blockade in kidney transplant recipients?

Output: renin-angiotensin system blockade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does angiotensin II blockade in kidney transplant recipients?. ### Response: renin-angiotensin system blockade.


Instruction: How does candesartan improve bloodpressure control and reduce proteinuria?

Output: results from SECRET

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does candesartan improve bloodpressure control and reduce proteinuria?. ### Response: results from SECRET.


Instruction: When did Salzberg DJ, Karadsheh FF, Haririan A, et al. publish?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Salzberg DJ, Karadsheh FF, Haririan A, et al. publish?. ### Response: 2010.


Instruction: What is a potential randomized trial of calcium channel blockade and preservation of renal graft function in cyclosporine-treatedrecipients?

Output: placebo-controlled 2-year study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential randomized trial of calcium channel blockade and preservation of renal graft function in cyclosporine-treatedrecipients?. ### Response: placebo-controlled 2-year study.


Instruction: What is the name of the prospective randomized placebo-controlled 2-year study?

Output: Calcium channel blockadeand preservation of renal graft function in cyclosporine-treatedrecipients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective randomized placebo-controlled 2-year study?. ### Response: Calcium channel blockadeand preservation of renal graft function in cyclosporine-treatedrecipients.


Instruction: What is cyclosporine used for?

Output: preservation of renal graft function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cyclosporine used for?. ### Response: preservation of renal graft function.


Instruction: How long did the study last?

Output: 2-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: 2-year.


Instruction: What is the name of the kidney transplantation that causes hypertension?

Output: renaltransplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the kidney transplantation that causes hypertension?. ### Response: renaltransplantation.


Instruction: What is another name for converting enzyme blockade?

Output: Calcium channel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for converting enzyme blockade?. ### Response: Calcium channel.


Instruction: In what year did Nephrol Dial Transplant issue 14:384-388.334?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Nephrol Dial Transplant issue 14:384-388.334?. ### Response: 1999.


Instruction: What is amlodipinein normotensive renal transplant recipients treated with?

Output: reduced dose of cyclosporine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is amlodipinein normotensive renal transplant recipients treated with?. ### Response: reduced dose of cyclosporine.


Instruction: What is the effect of nifedipine on renalhaemodynamics and urinary protein excretion in stable renaltransplant recipients?

Output: reduces proteinuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of nifedipine on renalhaemodynamics and urinary protein excretion in stable renaltransplant recipients?. ### Response: reduces proteinuria.


Instruction: What type of edema is associated with calcium channel blockers?

Output: Peripheral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of edema is associated with calcium channel blockers?. ### Response: Peripheral.


Instruction: What is the incidence and withdrawal rate of calcium channel blocks?

Output: Peripheral edema

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence and withdrawal rate of calcium channel blocks?. ### Response: Peripheral edema.


Instruction: When was the J Hypertens.29:1270 – 1280.336?

Output: 1995

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Hypertens.29:1270 – 1280.336?. ### Response: 1995.


Instruction: What is a UK general practice-basedcohort study?

Output: Adherence to guidelines forcreatinine and potassium monitoring and discontinuation followingrenin-angiotensin system blockade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a UK general practice-basedcohort study?. ### Response: Adherence to guidelines forcreatinine and potassium monitoring and discontinuation followingrenin-angiotensin system blockade.


Instruction: What is the name of the randomized controlled trial?

Output: Amara AB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial?. ### Response: Amara AB.


Instruction: What is the name of the STARNet study?

Output: Participatory decision making, patient activation, medication adherence, and intermediate clini-cal outcomes in type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the STARNet study?. ### Response: Participatory decision making, patient activation, medication adherence, and intermediate clini-cal outcomes in type 2 diabetes.


Instruction: What is a social determinant of risk and outcomes for cardiovascular disease?

Output: socioeconomic factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a social determinant of risk and outcomes for cardiovascular disease?. ### Response: socioeconomic factors.


Instruction: What is a scientific statement from the American Heart Association?

Output: Social determinants of risk and outcomes for cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scientific statement from the American Heart Association?. ### Response: Social determinants of risk and outcomes for cardiovascular disease.


Instruction: Circulation. 2015;132:873-98.

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2015;132:873-98.. ### Response: 2015.


Instruction: What is the purpose of interventions targeting behavioral factors among individuals with low levels of education?

Output: Reducing health inequalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of interventions targeting behavioral factors among individuals with low levels of education?. ### Response: Reducing health inequalities.


Instruction: What is the name of the journal that studies the relationship between socioeconomic status and cardiovascular disease?

Output: BMC Public Health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the relationship between socioeconomic status and cardiovascular disease?. ### Response: BMC Public Health.


Instruction: What are the challenges and interventions of Socioeconomic Status and cardiovascular outcomes?

Output: Sex differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the challenges and interventions of Socioeconomic Status and cardiovascular outcomes?. ### Response: Sex differences.


Instruction: What is a systematic review and meta-analysis of cardiovascular disease?

Output: Effects of education and income on cardiovascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis of cardiovascular disease?. ### Response: Effects of education and income on cardiovascular outcomes.


Instruction: What is the J Epidemiol Community Health. 2017;71:550–7?

Output: Sex differences in the rela-tionship between socioeconomic status and cardiovascular disease: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Epidemiol Community Health. 2017;71:550–7?. ### Response: Sex differences in the rela-tionship between socioeconomic status and cardiovascular disease: a systematic review and meta-analysis.


Instruction: Beauchamp A, Peeters A, Tonkin A, et al. Best practice for prevention and treatment of what disease through an equity lens: a review?

Output: cardiovascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beauchamp A, Peeters A, Tonkin A, et al. Best practice for prevention and treatment of what disease through an equity lens: a review?. ### Response: cardiovascular.


Instruction: What is a systematic review and meta-analysis of the effects of education and income on cardiovascular outcomes?

Output: Sex differences in the rela-tionship between socioeconomic status and cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis of the effects of education and income on cardiovascular outcomes?. ### Response: Sex differences in the rela-tionship between socioeconomic status and cardiovascular disease.


Instruction: What is the name of the study that evaluated the evidence for models of life course socioeconomic factors and cardiovascular outcomes in the United States?

Output: a systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the evidence for models of life course socioeconomic factors and cardiovascular outcomes in the United States?. ### Response: a systematic review.


Instruction: What is a systematic review of models of life course socioeconomic factors and cardiovascular outcomes?

Output: BMC Public Health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of models of life course socioeconomic factors and cardiovascular outcomes?. ### Response: BMC Public Health.


Instruction: What is the name of the AHRQ Publication No. 16-0002-EF?

Output: Agency for Healthcare Research and Quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the AHRQ Publication No. 16-0002-EF?. ### Response: Agency for Healthcare Research and Quality.


Instruction: Where is the US Department of Health and Human Services located?

Output: Rockville

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the US Department of Health and Human Services located?. ### Response: Rockville.


Instruction: What is the name of the 2015 ACC health policy statement on cardiovascular team-based care?

Output: Brush

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2015 ACC health policy statement on cardiovascular team-based care?. ### Response: Brush.


Instruction: How does treatment in a preventive cardiology clinic utilizing advanced practice providers effectively close atherosclerotic cardiovascular disease risk-management gaps among a primary-prevention population compared with a propen-sity-matched primary-care cohort?

Output: team-based care model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does treatment in a preventive cardiology clinic utilizing advanced practice providers effectively close atherosclerotic cardiovascular disease risk-management gaps among a primary-prevention population compared with a propen-sity-matched primary-care cohort?. ### Response: team-based care model.


Instruction: What is the team-based care model?

Output: Patient-centered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the team-based care model?. ### Response: Patient-centered.


Instruction: What is a team-based care model and its impact on lipid and blood pressure management?

Output: rosclerotic cardiovascular disease risk-management gaps among a primary-prevention population compared with a propen-sity-matched primary-care cohort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a team-based care model and its impact on lipid and blood pressure management?. ### Response: rosclerotic cardiovascular disease risk-management gaps among a primary-prevention population compared with a propen-sity-matched primary-care cohort.


Instruction: What is the Accountable Health Communities Screening Tool?

Output: Standardized Screening for Health-Related Social Needs in Clinical Settings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Accountable Health Communities Screening Tool?. ### Response: Standardized Screening for Health-Related Social Needs in Clinical Settings.


Instruction: Where is Standardized Screening for Health-Related Social Needs in Clinical Settings available?

Output: The Accountable Health Communities Screening Tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Standardized Screening for Health-Related Social Needs in Clinical Settings available?. ### Response: The Accountable Health Communities Screening Tool.


Instruction: Where is the Accountable Health Communities Screening Tool available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Accountable Health Communities Screening Tool available?. ### Response: https://nam.


Instruction: What is the name of the document that is available at https://nam.nam.edu/wp-content/uploads/2017/05/Standardized-Screening-for-Health-Related-Social-Needs-in-Clinical-Settings.pdf?

Output: The Accountable Health Communities Screening Tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that is available at https://nam.nam.edu/wp-content/uploads/2017/05/Standardized-Screening-for-Health-Related-Social-Needs-in-Clinical-Settings.pdf?. ### Response: The Accountable Health Communities Screening Tool.


Instruction: What is inherent in the low or very lowcertainty in the evidence?

Output: The limitations of these guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is inherent in the low or very lowcertainty in the evidence?. ### Response: The limitations of these guidelines.


Instruction: What may encounter clinical questions that were not included among those prioritized by the panel?

Output: clinicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may encounter clinical questions that were not included among those prioritized by the panel?. ### Response: clinicians.


Instruction: How will ASH maintain the guidelines after publication?

Output: throughsurveillance for new evidence, ongoing review by experts, and regularrevisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How will ASH maintain the guidelines after publication?. ### Response: throughsurveillance for new evidence, ongoing review by experts, and regularrevisions.


Instruction: What is the name of the publication that ASH will continue to maintain after publication of the guidelines?

Output: 3282 WITT et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the publication that ASH will continue to maintain after publication of the guidelines?. ### Response: 3282 WITT et al.


Instruction: When was this publication published?

Output: 27 NOVEMBER 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication published?. ### Response: 27 NOVEMBER 2018.


Instruction: How many sessions of CR are Medicare beneficiaries covered for after a surgical hospitalization?

Output: 36

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sessions of CR are Medicare beneficiaries covered for after a surgical hospitalization?. ### Response: 36.


Instruction: How long are patients covered for for CABG?

Output: up to 36 sessions of CR over the course of 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long are patients covered for for CABG?. ### Response: up to 36 sessions of CR over the course of 1 year.


Instruction: What is the length of time that patients are covered for CR?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the length of time that patients are covered for CR?. ### Response: 1 year.


Instruction: What percentage of CABG patients received at least 1 session of CR?

Output: 31%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of CABG patients received at least 1 session of CR?. ### Response: 31%.


Instruction: What is one of the key barriers to CR use?

Output: the process of refer -ral to CR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the key barriers to CR use?. ### Response: the process of refer -ral to CR.


Instruction: How many hospitals use the AHA Get With The Guidelines program?

Output: 327

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hospitals use the AHA Get With The Guidelines program?. ### Response: 327.


Instruction: What is a key area in need of greater focus?

Output: improving referral patterns to CR programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key area in need of greater focus?. ### Response: improving referral patterns to CR programs.


Instruction: When was Recognizing Downloaded from http://ahajournals.org by?

Output: April 26, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Recognizing Downloaded from http://ahajournals.org by?. ### Response: April 26, 2023.


Instruction: What is the name of the patient who underwent Valve Surgery?

Output: Graboys TB, Cohn PF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the patient who underwent Valve Surgery?. ### Response: Graboys TB, Cohn PF.


Instruction: What is Graboys TB, Cohn PF's affiliation with?

Output: angina pectoris and abnormal coronary arteriograms in severe aortic valvular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Graboys TB, Cohn PF's affiliation with?. ### Response: angina pectoris and abnormal coronary arteriograms in severe aortic valvular disease.


Instruction: When was angina pectoris and abnormal coronary arteriograms found in severe aortic valvular disease?

Output: 1977

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was angina pectoris and abnormal coronary arteriograms found in severe aortic valvular disease?. ### Response: 1977.


Instruction: What is coronary artery disease in patients with valvular disease?

Output: coronary risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is coronary artery disease in patients with valvular disease?. ### Response: coronary risk factors.


Instruction: What is the name of the prospective study?

Output: Ramsdale DR, Bennett DH, Bray CL, et al. Angina, coronary risk factors and coronary artery disease in patients with valvular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study?. ### Response: Ramsdale DR, Bennett DH, Bray CL, et al. Angina, coronary risk factors and coronary artery disease in patients with valvular disease.


Instruction: When was this study published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 28, 2023.


Instruction: What is a sign of dysplasia of the pulmonary valve?

Output: significant hypoplasia of the annulus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a sign of dysplasia of the pulmonary valve?. ### Response: significant hypoplasia of the annulus.


Instruction: What can be relieved in an asymptomatic patient to reduce the RV pressure?

Output: severely stenotic pulmonary valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be relieved in an asymptomatic patient to reduce the RV pressure?. ### Response: severely stenotic pulmonary valve.


Instruction: What will reduce the RV pressure and the possibility of potential sequelae?

Output: Relief of a severely stenotic pulmonary valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will reduce the RV pressure and the possibility of potential sequelae?. ### Response: Relief of a severely stenotic pulmonary valve.


Instruction: What can be per-formed by surgery or interventional catheterization with low morbidity and mortality?

Output: symptomatic patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be per-formed by surgery or interventional catheterization with low morbidity and mortality?. ### Response: symptomatic patients.


Instruction: What may prompt reconsideration of intervention?

Output: careful follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may prompt reconsideration of intervention?. ### Response: careful follow-up.


Instruction: What is important to evaluate for?

Output: PR, RV size and function, and functional capacity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to evaluate for?. ### Response: PR, RV size and function, and functional capacity.


Instruction: What is recommended in symptomatic patients with moderate or greater PR resulting from treated isolated pulmonary stenosis?

Output: pulmonary valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in symptomatic patients with moderate or greater PR resulting from treated isolated pulmonary stenosis?. ### Response: pulmonary valve replacement.


Instruction: What is pulmonary valve replacement recommended in?

Output: Supportive Text

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is pulmonary valve replacement recommended in?. ### Response: Supportive Text.


Instruction: What is recommended for patients with dilated right ventricle?

Output: serial follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with dilated right ventricle?. ### Response: serial follow-up.


Instruction: What type of valve replacement may be reasonable in asymptomatic patients with moderate or greater PR?

Output: pulmonary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve replacement may be reasonable in asymptomatic patients with moderate or greater PR?. ### Response: pulmonary.


Instruction: Patients with valvular PS do not require what?

Output: intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with valvular PS do not require what?. ### Response: intervention.


Instruction: What can be alleviated by surgical valvotomy or with balloon valvuloplasty?

Output: PS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be alleviated by surgical valvotomy or with balloon valvuloplasty?. ### Response: PS.


Instruction: Either surgical or catheter inter-vention may result in what type of PR?

Output: hemodynamically important

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Either surgical or catheter inter-vention may result in what type of PR?. ### Response: hemodynamically important.


Instruction: What may result in hemodynamically important PR that can result in symptoms, RV enlargement, and/or dysfunction requiring pulmonary valve replacement?

Output: Either surgical or catheter inter -vention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may result in hemodynamically important PR that can result in symptoms, RV enlargement, and/or dysfunction requiring pulmonary valve replacement?. ### Response: Either surgical or catheter inter -vention.


Instruction: Patients with isolated PS who have previously undergone an intervention on the pulmonary valve require ongoing clinical follow-up and what else?

Output: mon-itoring of PR, RV size and function, and functional capacity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with isolated PS who have previously undergone an intervention on the pulmonary valve require ongoing clinical follow-up and what else?. ### Response: mon-itoring of PR, RV size and function, and functional capacity.


Instruction: What may follow-up and mon-itoring of PR, RV size and function, and functional capacity include?

Output: echocardiography, CPET, and advanced imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may follow-up and mon-itoring of PR, RV size and function, and functional capacity include?. ### Response: echocardiography, CPET, and advanced imaging.


Instruction: What may include echocardiography, CPET, and advanced imaging?

Output: Patients with isolated PS who have previously undergone an intervention on the pulmonary valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may include echocardiography, CPET, and advanced imaging?. ### Response: Patients with isolated PS who have previously undergone an intervention on the pulmonary valve.


Instruction: The right ventricle in patients with PR after intervention for PS may be smaller than what?

Output: in patients with TOF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The right ventricle in patients with PR after intervention for PS may be smaller than what?. ### Response: in patients with TOF.


Instruction: Patients with PR may have evidence of decreased RV ejection.

Output: RV dilation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with PR may have evidence of decreased RV ejection.. ### Response: RV dilation.


Instruction: What may patients with PR have evidence of?

Output: decreased RV ejection fraction or decreased exercise ca-pacity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients with PR have evidence of?. ### Response: decreased RV ejection fraction or decreased exercise ca-pacity.


Instruction: What can improve symptoms for patients with symptoms that are attributable to moderate or greater PR?

Output: Pulmonary valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can improve symptoms for patients with symptoms that are attributable to moderate or greater PR?. ### Response: Pulmonary valve replacement.


Instruction: Pulmonary valve replacement can improve RV size and function if there is what?

Output: RV dilation or decreased RV ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pulmonary valve replacement can improve RV size and function if there is what?. ### Response: RV dilation or decreased RV ejection fraction.


Instruction: What happens if there is RV dilation or decreased RV ejection fraction?

Output: improve RV size and/or RV function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What happens if there is RV dilation or decreased RV ejection fraction?. ### Response: improve RV size and/or RV function.


Instruction: Who helped with the development of this guideline?

Output: Professor Martin Cowie

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who helped with the development of this guideline?. ### Response: Professor Martin Cowie.


Instruction: Who reviewed the economic model methodology section prior to the guideline development?

Output: Professor Martin Cowie

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reviewed the economic model methodology section prior to the guideline development?. ### Response: Professor Martin Cowie.


Instruction: Cowie for reviewing the economic model methodology section prior to running what?

Output: sensitivity analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cowie for reviewing the economic model methodology section prior to running what?. ### Response: sensitivity analyses.


Instruction: What is LATE?

Output: Late Assessment of Thrombolytic Efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LATE?. ### Response: Late Assessment of Thrombolytic Efficacy.


Instruction: How long after onset of acute myocardial infarction does LATE study use al-teplase?

Output: 6–24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after onset of acute myocardial infarction does LATE study use al-teplase?. ### Response: 6–24 hours.


Instruction: What is the name of the collaborative group that compares intravenous urokinase plus heparin versus hparin alone?

Output: Urochinasi per via Sistemica nell’Infarto Miocardico (USIM) Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the collaborative group that compares intravenous urokinase plus heparin versus hparin alone?. ### Response: Urochinasi per via Sistemica nell’Infarto Miocardico (USIM) Collaborative Group.


Instruction: What is the acronym for the USIM Collaborative Group?

Output: Urochinasi per via Sistemica nell’Infarto Miocardico

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the USIM Collaborative Group?. ### Response: Urochinasi per via Sistemica nell’Infarto Miocardico.


Instruction: What was the name of the colloquial group that developed USIM?

Output: Urochinasi per via Sistemica nell’Infarto Miocardico

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the colloquial group that developed USIM?. ### Response: Urochinasi per via Sistemica nell’Infarto Miocardico.


Instruction: When was the file downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the file downloaded?. ### Response: April 28, 2023.


Instruction: What is the AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes?

Output: Author Relationships With Industry and Other Entities (Relevant)–2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes?. ### Response: Author Relationships With Industry and Other Entities (Relevant)–2014.


Instruction: Who is the Author Relationships With Industry and Other Entities (Relevant)?

Output: –2014 AHA/ACC Guideline for the Management  of Patients With Non-ST -Elevation Acute Coronary Syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Author Relationships With Industry and Other Entities (Relevant)?. ### Response: –2014 AHA/ACC Guideline for the Management  of Patients With Non-ST -Elevation Acute Coronary Syndromes.


Instruction: Who is the Vice Chair of the School of Medicine at Emory University?

Output: Nanette K. Wenger

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Chair of the School of Medicine at Emory University?. ### Response: Nanette K. Wenger.


Instruction: What is the name of the company that is the vice chair of the school of medicine?

Output: Nanette K. Wenger

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the company that is the vice chair of the school of medicine?. ### Response: Nanette K. Wenger.


Instruction: Who is a vice president of the university of California (Davis) Medical Center?

Output: Donald E. Casey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a vice president of the university of California (Davis) Medical Center?. ### Response: Donald E. Casey.


Instruction: Who is the professor of medicine at the University of California, San Francisco?

Output: Ralph G. Brindis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of medicine at the University of California, San Francisco?. ### Response: Ralph G. Brindis.


Instruction: Where is the department of medicine located?

Output: San Francisco

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the department of medicine located?. ### Response: San Francisco.


Instruction: What is the name of the company that is associated with Amgen?

Output: Abbott

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the company that is associated with Amgen?. ### Response: Abbott.


Instruction: Where is the Phillip R. Lee Institute for Health Policy Studies located?

Output: San Francisco

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Phillip R. Lee Institute for Health Policy Studies located?. ### Response: San Francisco.


Instruction: Who is the Vice President of Health and Chief Medical Officer of Atlantic Health?

Output: Donald E. Casey, Jr

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice President of Health and Chief Medical Officer of Atlantic Health?. ### Response: Donald E. Casey, Jr.


Instruction: What is the name of the University of California, San Francisco Department of Medicine?

Output: Ralph G. Brindis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the University of California, San Francisco Department of Medicine?. ### Response: Ralph G. Brindis.


Instruction: Who is the Executive Director of Health Services Research Center at the University of California, San Diego School of Medicine?

Output: Theodore G. Ganiats

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Executive Director of Health Services Research Center at the University of California, San Diego School of Medicine?. ### Response: Theodore G. Ganiats.


Instruction: What is the name of the cardiovascular division of the Mayo Clinic?

Output: Allan S.  JaffeMayo Clinic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the cardiovascular division of the Mayo Clinic?. ### Response: Allan S.  JaffeMayo Clinic.


Instruction: What is the name of the Cardiovascular Division?

Output: Allan S.  JaffeMayo Clinic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Cardiovascular Division?. ### Response: Allan S.  JaffeMayo Clinic.


Instruction: Who is the professor of medicine at the JaffeMayo Clinic?

Output: Allan S.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of medicine at the JaffeMayo Clinic?. ### Response: Allan S..


Instruction: Where is the cardiovascular division located?

Output: University of California (Davis) Medical Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the cardiovascular division located?. ### Response: University of California (Davis) Medical Center.


Instruction: Who is the Assistant Professor of Medicine at the Michael E. DeBakey VA Medical Center?

Output: Hani Jneid Baylor College of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Assistant Professor of Medicine at the Michael E. DeBakey VA Medical Center?. ### Response: Hani Jneid Baylor College of Medicine.


Instruction: On what date was this article downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was this article downloaded?. ### Response: April 28, 2023.


Instruction: What are noninvasive and invasive testing particularly related to?

Output: the assessment of LV systolic function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are noninvasive and invasive testing particularly related to?. ### Response: the assessment of LV systolic function.


Instruction: What identify individuals who should undergo urgent coronary angiography with intent to perform PCI?

Output: clinical and ECG  indicators of failed reperfusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What identify individuals who should undergo urgent coronary angiography with intent to perform PCI?. ### Response: clinical and ECG  indicators of failed reperfusion.


Instruction: What is one of the strongest predictors of higher-mortality risk after STEMI?

Output: the emergence of HF or signifi-cant LV systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the strongest predictors of higher-mortality risk after STEMI?. ### Response: the emergence of HF or signifi-cant LV systolic dysfunction.


Instruction: Stable patients with a low risk of complications may be candidates for what?

Output: early discharge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stable patients with a low risk of complications may be candidates for what?. ### Response: early discharge.


Instruction: What is STEMI managed with fibrinolysis?

Output: uncomplicated course after 72 hours of hospitalization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is STEMI managed with fibrinolysis?. ### Response: uncomplicated course after 72 hours of hospitalization.


Instruction: How long after 72 hours of hospitalization does STEMI manage?

Output: uncomplicated course

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after 72 hours of hospitalization does STEMI manage?. ### Response: uncomplicated course.


Instruction: What is the cost of extending the hospital stay of STEMI patients by another day?

Output: $105 629 per year of life saved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost of extending the hospital stay of STEMI patients by another day?. ### Response: $105 629 per year of life saved.


Instruction: How much would it cost to save a person's life if they were hospitalized?

Output: $105 629 per year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much would it cost to save a person's life if they were hospitalized?. ### Response: $105 629 per year.


Instruction: How much money would be saved if a patient was hospitalized by another day?

Output: $105 629 per year of life saved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much money would be saved if a patient was hospitalized by another day?. ### Response: $105 629 per year of life saved.


Instruction: What is one way that doctors and patients can reduce risk?

Output: lifestyle interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one way that doctors and patients can reduce risk?. ### Response: lifestyle interventions.


Instruction: What are patients with STEMI considered to be at sufficiently high risk to merit interventions for secondary prevention?

Output: cardiac rehabilitation, aspi-rin, lipid-lowering therapy, beta blockers, and ACE inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with STEMI considered to be at sufficiently high risk to merit interventions for secondary prevention?. ### Response: cardiac rehabilitation, aspi-rin, lipid-lowering therapy, beta blockers, and ACE inhibitors.


Instruction: What must patients individualize strategies for?

Output: risk reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must patients individualize strategies for?. ### Response: risk reduction.


Instruction: What should be used to guide decisions about performance of coronary angiography in patients who did not undergo an invasive evaluation as part of their initial treatment strategy?

Output: Additional risk assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used to guide decisions about performance of coronary angiography in patients who did not undergo an invasive evaluation as part of their initial treatment strategy?. ### Response: Additional risk assessment.


Instruction: What should be performed before discharge to assess the presence and extent of inducible ischemia in patients?

Output: Noninvasive testing for ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed before discharge to assess the presence and extent of inducible ischemia in patients?. ### Response: Noninvasive testing for ischemia.


Instruction: What is the level of evidence for STEMI?

Output: All patients with STEMI are considered to be at sufficiently high risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for STEMI?. ### Response: All patients with STEMI are considered to be at sufficiently high risk.


Instruction: What might noninvasive testing be considered before discharge?

Output: ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might noninvasive testing be considered before discharge?. ### Response: ischemia.


Instruction: What might be considered before discharge to evaluate the functional signifi-cance of a noninfarct artery stenosis previously iden-tified at angiography?

Output: Noninvasive testing for ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered before discharge to evaluate the functional signifi-cance of a noninfarct artery stenosis previously iden-tified at angiography?. ### Response: Noninvasive testing for ischemia.


Instruction: What provides valuable information about the presence of residual ischemia in patients who have not undergone cardiac catheterization during initial management of STEMI?

Output: Noninvasive testing for ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides valuable information about the presence of residual ischemia in patients who have not undergone cardiac catheterization during initial management of STEMI?. ### Response: Noninvasive testing for ischemia.


Instruction: What may be useful in assessing the functional significance of a noninfarct artery stenosis?

Output: Noninvasive testing for ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be useful in assessing the functional significance of a noninfarct artery stenosis?. ### Response: Noninvasive testing for ischemia.


Instruction: What is the name of the book that chronic heart failure methods is based on?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that chronic heart failure methods is based on?. ### Response: NICE 2018.


Instruction: What is a low confidence?

Output: It is possible that the review finding is a reasonable representation of the phenomenon of interest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a low confidence?. ### Response: It is possible that the review finding is a reasonable representation of the phenomenon of interest.


Instruction: Is the review finding a reasonable representation of the phenomenon of interest?

Output: It is not clear

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is the review finding a reasonable representation of the phenomenon of interest?. ### Response: It is not clear.


Instruction: What software was used to assess against potential publication bias?

Output: RevMan5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What software was used to assess against potential publication bias?. ### Response: RevMan5.


Instruction: What was taken into consideration when assessing the quality of the evidence?

Output: Publication bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was taken into consideration when assessing the quality of the evidence?. ### Response: Publication bias.


Instruction: How many studies were included in an intervention review?

Output: more than 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included in an intervention review?. ### Response: more than 5.


Instruction: What did the committee assess to determine if there was a clinically important benefit or harm?

Output: the evidence by outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee assess to determine if there was a clinically important benefit or harm?. ### Response: the evidence by outcome.


Instruction: What was converted into absolute risk differences?

Output: binar y outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was converted into absolute risk differences?. ### Response: binar y outcomes.


Instruction: What was converted into absolute risk differences (ARDs) using GRADEpro138 software?

Output: binar y outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was converted into absolute risk differences (ARDs) using GRADEpro138 software?. ### Response: binar y outcomes.


Instruction: What was used to calculate the ARD and its 95% CI from the pooled risk ratio?

Output: the median control group risk across studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to calculate the ARD and its 95% CI from the pooled risk ratio?. ### Response: the median control group risk across studies.


Instruction: What was based on the point estimate of absolute effect for intervention studies?

Output: The assessment of clinical benefit, har m, or no benefit or harm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was based on the point estimate of absolute effect for intervention studies?. ### Response: The assessment of clinical benefit, har m, or no benefit or harm.


Instruction: What was standardised across the reviews?

Output: point estimate of absolute effect for intervention studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was standardised across the reviews?. ### Response: point estimate of absolute effect for intervention studies.


Instruction: The committee considered for most of the outcomes in what?

Output: intervention reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee considered for most of the outcomes in what?. ### Response: intervention reviews.


Instruction: How many more partici pants per 1000 achieved the outcome of interest in the intervention group compared to the comparison group for a positive outcome?

Output: 100

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many more partici pants per 1000 achieved the outcome of interest in the intervention group compared to the comparison group for a positive outcome?. ### Response: 100.


Instruction: What was considered beneficial if the same point estimate but in the opposite direction applied?

Output: a ne gative outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered beneficial if the same point estimate but in the opposite direction applied?. ### Response: a ne gative outcome.


Instruction: What did the opposite apply for a ne gative outcome?

Output: clinical benefit or harm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the opposite apply for a ne gative outcome?. ### Response: clinical benefit or harm.


Instruction: For the critical outcome of mortality any reduction represented a clinical benefit.

Output: The same point estimate but in the opposite direction applied for a ne gative outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For the critical outcome of mortality any reduction represented a clinical benefit.. ### Response: The same point estimate but in the opposite direction applied for a ne gative outcome.


Instruction: For adverse events 50 events or more per 1000 represented what?

Output: clinical harm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For adverse events 50 events or more per 1000 represented what?. ### Response: clinical harm.


Instruction: What is MID?

Output: minimally important difference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MID?. ### Response: minimally important difference.


Instruction: What was considered to be clinical important?

Output: any reduction or increase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered to be clinical important?. ### Response: any reduction or increase.


Instruction: Who carried out the assessment for each critical outcome?

Output: the committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who carried out the assessment for each critical outcome?. ### Response: the committee.


Instruction: What was produced to compile the committee’s assessments of clinical importance per outcome?

Output: an  evidence summary table

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was produced to compile the committee’s assessments of clinical importance per outcome?. ### Response: an  evidence summary table.


Instruction: What is the uncertainty in the effect estimate called?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the uncertainty in the effect estimate called?. ### Response: imprecision.


Instruction: What are Clinical e vidence statemen ts?

Output: summary statements that are included in each review chapter, and which  summaris e the key features of the clinical effectiveness evidence presented

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Clinical e vidence statemen ts?. ### Response: summary statements that are included in each review chapter, and which  summaris e the key features of the clinical effectiveness evidence presented.


Instruction: What are summary statements that are included in each review chapter?

Output: Clinical e vidence statemen ts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are summary statements that are included in each review chapter?. ### Response: Clinical e vidence statemen ts.


Instruction: The wording of the evidence statements reflect the certainty or uncertainty in what?

Output: the estimate of effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The wording of the evidence statements reflect the certainty or uncertainty in what?. ### Response: the estimate of effect.


Instruction: What reflects the certainty or uncertainty in the estimate of effect?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reflects the certainty or uncertainty in the estimate of effect?. ### Response: imprecision.


Instruction: What are the evidence statements presented by?

Output: outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the evidence statements presented by?. ### Response: outcome.


Instruction: What are the roles of C-reactive protein and coronary artery calcium?

Output: Risk stratification for primary prevention of coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the roles of C-reactive protein and coronary artery calcium?. ### Response: Risk stratification for primary prevention of coronary artery disease.


Instruction: What is the name of the study that investigated risk stratification for primary prevention of cardiovascular disease?

Output: Jackson Heart study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated risk stratification for primary prevention of cardiovascular disease?. ### Response: Jackson Heart study.


Instruction: What is atherosclero-sis?

Output: Subclinical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atherosclero-sis?. ### Response: Subclinical.


Instruction: What is statin eligibility?

Output: outcomes in African American individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is statin eligibility?. ### Response: outcomes in African American individuals.


Instruction: When did the Jackson Heart study take place?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Jackson Heart study take place?. ### Response: 2017.


Instruction: How did the St Francis Heart Study compare outcomes?

Output: Collective impact of conven-tional cardiovascular risk factors and coronary calcium score on clini-cal outcomes with or without statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the St Francis Heart Study compare outcomes?. ### Response: Collective impact of conven-tional cardiovascular risk factors and coronary calcium score on clini-cal outcomes with or without statin therapy.


Instruction: What did the St Francis Heart Study do with or without statin therapy?

Output: clini-cal outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the St Francis Heart Study do with or without statin therapy?. ### Response: clini-cal outcomes.


Instruction: What is the name of the study?

Output: Jackson Heart study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: Jackson Heart study.


Instruction: What is a summary ofstrategiesbased onexpertopinionforstartingandadd-ingantihypertensivedrugs?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a summary ofstrategiesbased onexpertopinionforstartingandadd-ingantihypertensivedrugs?. ### Response: Recommendation9isasummary.


Instruction: What aretheevidencestatementssupportingtherecommendationsintheonlineSupplement?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What aretheevidencestatementssupportingtherecommendationsintheonlineSupplement?. ### Response: NationalHighBloodPressureEducationProgramCoordinatingCommittee,acoalitionof39majorprofessional,pub-lic,andvoluntaryorganizationsand7federalagenciesReviewedbyexpertsincludingthoseaffiliatedwithprofessionalandpublicorganizationsandfederalagencies.


Instruction: How many majorprofessional,pub-lic,andvoluntaryorganizations are involved in the review process?

Output: 39

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many majorprofessional,pub-lic,andvoluntaryorganizations are involved in the review process?. ### Response: 39.


Instruction: What is an established feature of heart valve programs?

Output: The MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an established feature of heart valve programs?. ### Response: The MDT.


Instruction: What has been formally endorsed by the ACC?

Output: The MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been formally endorsed by the ACC?. ### Response: The MDT.


Instruction: What are the key members of the MDT?

Output: cardiologists with subspecialty expertise in the clinical evaluation of patients with VHD, as well as specialists in advanced cardiovas-cular imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the key members of the MDT?. ### Response: cardiologists with subspecialty expertise in the clinical evaluation of patients with VHD, as well as specialists in advanced cardiovas-cular imaging.


Instruction: What are cardiologists with subspecialty expertise in?

Output: clinical evaluation of patients with VHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are cardiologists with subspecialty expertise in?. ### Response: clinical evaluation of patients with VHD.


Instruction: What is MR?

Output: secondary mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MR?. ### Response: secondary mitral regurgitation.


Instruction: What is TR?

Output: tri-cuspid regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TR?. ### Response: tri-cuspid regurgitation.


Instruction: Who is included in the evaluation of patients with VHD?

Output: cardiologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is included in the evaluation of patients with VHD?. ### Response: cardiologists.


Instruction: Who anchors the MDT?

Output: Interventional cardiologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who anchors the MDT?. ### Response: Interventional cardiologists.


Instruction: What is of critical importance to the engagement of the primary clinical cardiologist and patient?

Output: The MDT facilitates presenta-tion of all appropriate options for medical, inter -ventional, and surgical treatment to the patient in a balanced manner

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is of critical importance to the engagement of the primary clinical cardiologist and patient?. ### Response: The MDT facilitates presenta-tion of all appropriate options for medical, inter -ventional, and surgical treatment to the patient in a balanced manner.


Instruction: The MDT facilitates presenta-tion of what?

Output: heart valve programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The MDT facilitates presenta-tion of what?. ### Response: heart valve programs.


Instruction: What facilitates presenta-tion of all appropriate options for medical, inter-ventional, and surgical treatment to the patient in a balanced manner?

Output: The MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What facilitates presenta-tion of all appropriate options for medical, inter-ventional, and surgical treatment to the patient in a balanced manner?. ### Response: The MDT.


Instruction: What tools and techniques are used for shared decision-making in which patient prefer ences are considered?

Output: trans-catheter and surgical approaches

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tools and techniques are used for shared decision-making in which patient prefer ences are considered?. ### Response: trans-catheter and surgical approaches.


Instruction: Decision-making is particularly challenging for the asymptomatic VHD patient?

Output: assurance of outcomes equivalent to those of a higher-volume center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Decision-making is particularly challenging for the asymptomatic VHD patient?. ### Response: assurance of outcomes equivalent to those of a higher-volume center.


Instruction: What are the risks of operative mortality and perioperative morbidity for the asymptomatic VHD patient?

Output: Decision-making is particularly challenging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risks of operative mortality and perioperative morbidity for the asymptomatic VHD patient?. ### Response: Decision-making is particularly challenging.


Instruction: What must be very low and the chances of a successful and durable surgical outcome very high?

Output: the risks of operative mortality and perioperative morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be very low and the chances of a successful and durable surgical outcome very high?. ### Response: the risks of operative mortality and perioperative morbidity.


Instruction: There is a substantial body of literature to support what?

Output: a relationship between institutional vol-ume and mortality rate for many cardiovascular procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is a substantial body of literature to support what?. ### Response: a relationship between institutional vol-ume and mortality rate for many cardiovascular procedures.


Instruction: What is the relationship between institutional volume and mortality rate for many cardiovascular procedures?

Output: substantial body of literature to support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between institutional volume and mortality rate for many cardiovascular procedures?. ### Response: substantial body of literature to support.


Instruction: What should be considered for asymptomatic patients with severe VHD?

Output: consultation with or referral to a Primary or Comprehensive Heart Valve Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered for asymptomatic patients with severe VHD?. ### Response: consultation with or referral to a Primary or Comprehensive Heart Valve Center.


Instruction: Where can excellent outcomes be achieved for patients with severe VHD?

Output: lower-volume centers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can excellent outcomes be achieved for patients with severe VHD?. ### Response: lower-volume centers.


Instruction: What is statistically more challenging than a higher-volume center?

Output: assurance of outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is statistically more challenging than a higher-volume center?. ### Response: assurance of outcomes.


Instruction: How can care at a Comprehensive or Primary Valve Center ensure optimal outcomes?

Output: for patients with multiple comorbidities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can care at a Comprehensive or Primary Valve Center ensure optimal outcomes?. ### Response: for patients with multiple comorbidities.


Instruction: What ensures optimal outcomes at a Comprehensive or Primary Valve Center?

Output: multispecialty collaboration is anticipated, care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What ensures optimal outcomes at a Comprehensive or Primary Valve Center?. ### Response: multispecialty collaboration is anticipated, care.


Instruction: There are data to support relationships between center volume and complication rates in cardiac surgical care.

Output: 13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are data to support relationships between center volume and complication rates in cardiac surgical care.. ### Response: 13.


Instruction: What does VHD include both trans-catheter and surgical approaches?

Output: Interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does VHD include both trans-catheter and surgical approaches?. ### Response: Interventions.


Instruction: What does a valve intervene in?

Output: Interventions in patients with VHD include both trans-catheter and surgical approaches

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a valve intervene in?. ### Response: Interventions in patients with VHD include both trans-catheter and surgical approaches.