Instruction: When will the majority respond to standard methods of hypertension Download from http://ahajournals.org?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the majority respond to standard methods of hypertension Download from http://ahajournals.org?. ### Response: May 3, 2023.


Instruction: What is reduced by the use of systemic anticoagulation in the presence of L V thrombus?

Output: The associated risk of stroke or systemic embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reduced by the use of systemic anticoagulation in the presence of L V thrombus?. ### Response: The associated risk of stroke or systemic embolism.


Instruction: What is the risk of stroke or systemic embolism?

Output: increased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of stroke or systemic embolism?. ### Response: increased.


Instruction: What is used to reduce L V thrombus?

Output: systemic anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to reduce L V thrombus?. ### Response: systemic anticoagulation.


Instruction: What is reduced by using systemic anticoagulation?

Output: The associated risk of stroke or systemic embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reduced by using systemic anticoagulation?. ### Response: The associated risk of stroke or systemic embolism.


Instruction: How does thombus in the L V mature and become incorporated into the wall of the akinetic segment?

Output: Over time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does thombus in the L V mature and become incorporated into the wall of the akinetic segment?. ### Response: Over time.


Instruction: How long does it take for a thrombus to mature?

Output: ≈3 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a thrombus to mature?. ### Response: ≈3 months.


Instruction: What is an important determinant of stroke type and appropriate therapy?

Output: detection of L V thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important determinant of stroke type and appropriate therapy?. ### Response: detection of L V thrombus.


Instruction: Standard transthoracic echocar-diography is relatively insensitive for what?

Output: detection of L V thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Standard transthoracic echocar-diography is relatively insensitive for what?. ### Response: detection of L V thrombus.


Instruction: What is relatively insensitive for the detection of L V thrombus?

Output: Standard transthoracic echocar-diography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is relatively insensitive for the detection of L V thrombus?. ### Response: Standard transthoracic echocar-diography.


Instruction: What are superior imaging modalities for detecting L V?

Output: contrast echocardiography with the use of a microbubble contrast agent and cardiac MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are superior imaging modalities for detecting L V?. ### Response: contrast echocardiography with the use of a microbubble contrast agent and cardiac MRI.


Instruction: How is standard transthoracic echocar-diography sensitive?

Output: insensitive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is standard transthoracic echocar-diography sensitive?. ### Response: insensitive.


Instruction: What should patients with stroke or TIA be anticoagulated until the thrombus has matured and the risk of further embolism has waned?

Output: L V thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with stroke or TIA be anticoagulated until the thrombus has matured and the risk of further embolism has waned?. ### Response: L V thrombus.


Instruction: What has the bulk of evi-dence used for oral anticoagulation with a goal INR?

Output: VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has the bulk of evi-dence used for oral anticoagulation with a goal INR?. ### Response: VKA.


Instruction: What is the goal INR of VKA for oral anticoagulation?

Output: 2.0 to 3.0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal INR of VKA for oral anticoagulation?. ### Response: 2.0 to 3.0.


Instruction: How many patients were studied from 1979 to 1998?

Output: 2160

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were studied from 1979 to 1998?. ### Response: 2160.


Instruction: What was the risk of stroke after MI dramatically higher in the first month after infarct?

Output: elevated for years afterward

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of stroke after MI dramatically higher in the first month after infarct?. ### Response: elevated for years afterward.


Instruction: What percentage of patients with ST-segment elevation MI had L V thrombus?

Output: 3.5% and 7 .1%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with ST-segment elevation MI had L V thrombus?. ### Response: 3.5% and 7 .1%.


Instruction: How many patients with ante-rior ST-set elevation MI did a multicenter study identify?

Output: 753

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with ante-rior ST-set elevation MI did a multicenter study identify?. ### Response: 753.


Instruction: What has been noted in mural thrombosis?

Output: as many as 26% of those studied in other series

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been noted in mural thrombosis?. ### Response: as many as 26% of those studied in other series.


Instruction: What has been noted in as many as 26% of those studied in other series?

Output: mural thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been noted in as many as 26% of those studied in other series?. ### Response: mural thrombus.


Instruction: In a meta-analysis of 8 studies encompassing 856 patients, Vaitkus and Barnathan506 noted an increased risk of what?

Output: stroke or systemic embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a meta-analysis of 8 studies encompassing 856 patients, Vaitkus and Barnathan506 noted an increased risk of what?. ### Response: stroke or systemic embolism.


Instruction: What was the OR of L V thrombus?

Output: 5.45

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the OR of L V thrombus?. ### Response: 5.45.


Instruction: What was significantly reduced in the presence of oral anticoagulation?

Output: the risk of embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was significantly reduced in the presence of oral anticoagulation?. ### Response: the risk of embolism.


Instruction: How many patients were in a small single-center ret-rospective study?

Output: 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were in a small single-center ret-rospective study?. ### Response: 33.


Instruction: How many patients with L V thrombus were studied on cardiac MRI?

Output: 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with L V thrombus were studied on cardiac MRI?. ### Response: 33.


Instruction: What was the short-term risk of stroke in a single-center ret-rospective study of 33 patients?

Output: 9.1%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the short-term risk of stroke in a single-center ret-rospective study of 33 patients?. ### Response: 9.1%;.


Instruction: How many matched con-trols were studied?

Output: 2160

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many matched con-trols were studied?. ### Response: 2160.


Instruction: In a larger, more het-erogeneous study, what was observed in 7.7% of patients with docu-mented thrombosis?

Output: stroke or systemic embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a larger, more het-erogeneous study, what was observed in 7.7% of patients with docu-mented thrombosis?. ### Response: stroke or systemic embolism.


Instruction: How many patients with L V thrombus were compared with 400 matched patients over 3.3 years?

Output: 155

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with L V thrombus were compared with 400 matched patients over 3.3 years?. ### Response: 155.


Instruction: What was the annualized rate of stroke or systemic embolism in those without L Vthrom-bus?

Output: 0.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the annualized rate of stroke or systemic embolism in those without L Vthrom-bus?. ### Response: 0.8%.


Instruction: What percentage of patients with L V throm-bus had a higher risk of embolism than those without it?

Output: 0.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with L V throm-bus had a higher risk of embolism than those without it?. ### Response: 0.8%.


Instruction: What is the risk of an embo-lism that may persist?

Output: increased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of an embo-lism that may persist?. ### Response: increased.


Instruction: What type of heart failure does NICE 2018 address?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart failure does NICE 2018 address?. ### Response: Chronic Heart Failure.


Instruction: Who is subject to notice of rights?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is subject to notice of rights?. ### Response: Chronic Heart Failure.


Instruction: What is Table 147: Finding 1: Attitudes and understanding?

Output: Narrative summary of review findings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Table 147: Finding 1: Attitudes and understanding?. ### Response: Narrative summary of review findings.


Instruction: ICD recipients and family members were unaware that what could be deactivated?

Output: ICDs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ICD recipients and family members were unaware that what could be deactivated?. ### Response: ICDs.


Instruction: Misconception People perceived deactivation to be equivalent to what?

Output: euthanasia or suicide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Misconception People perceived deactivation to be equivalent to what?. ### Response: euthanasia or suicide.


Instruction: People did not want to deactivate regardless of the circumstances?

Output: the battery had run out, if they had an infection or an MRI was required

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People did not want to deactivate regardless of the circumstances?. ### Response: the battery had run out, if they had an infection or an MRI was required.


Instruction: Who wanted to deactivate when they were bedridden with an extremely low quality of life?

Output: People

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wanted to deactivate when they were bedridden with an extremely low quality of life?. ### Response: People.


Instruction: What did people not want to do regardless of the circumstances?

Output: deactivate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did people not want to do regardless of the circumstances?. ### Response: deactivate.


Instruction: How did patients feel about initiating the conversation?

Output: Some patients felt that healthcare professionals should start the conversation, whereas others felt that this would be emotionally distressing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did patients feel about initiating the conversation?. ### Response: Some patients felt that healthcare professionals should start the conversation, whereas others felt that this would be emotionally distressing.


Instruction: What did some patients feel healthcare professionals should do?

Output: start the conversation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some patients feel healthcare professionals should do?. ### Response: start the conversation.


Instruction: What did others feel would be emotionally distressing?

Output: Initiating the conversation  Some patients felt that healthcare professionals should start the conversation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did others feel would be emotionally distressing?. ### Response: Initiating the conversation  Some patients felt that healthcare professionals should start the conversation.


Instruction: When should discussions be started?

Output: early

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should discussions be started?. ### Response: early.


Instruction: What did some ICD recipients and healthcare professionals avoid discussing?

Output: deactivation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some ICD recipients and healthcare professionals avoid discussing?. ### Response: deactivation.


Instruction: What did they feel should occur later on or when there was a change in their condition?

Output: discussions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did they feel should occur later on or when there was a change in their condition?. ### Response: discussions.


Instruction: What did people with ICDs feel healthcare professionals should decide?

Output: whether or not a device should be deactivated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did people with ICDs feel healthcare professionals should decide?. ### Response: whether or not a device should be deactivated.


Instruction: Who felt that patients should decide when a device should be deactivated?

Output: Healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who felt that patients should decide when a device should be deactivated?. ### Response: Healthcare professionals.


Instruction: Who felt that patients should decide when to deactivate their device?

Output: Healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who felt that patients should decide when to deactivate their device?. ### Response: Healthcare professionals.


Instruction: What did Healthcare professionals feel patients should do?

Output: decide when to deactivate their device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Healthcare professionals feel patients should do?. ### Response: decide when to deactivate their device.


Instruction: Attitudes and understanding What did many ICD recipients and family members not know?

Output: ICDs could be deactivated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Attitudes and understanding What did many ICD recipients and family members not know?. ### Response: ICDs could be deactivated.


Instruction: What did family members not know about ICDs being deactivated?

Output: end of life care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did family members not know about ICDs being deactivated?. ### Response: end of life care.


Instruction: What was not discussed with them by their doctors?

Output: thoughts about dying

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not discussed with them by their doctors?. ### Response: thoughts about dying.


Instruction: What was not discussed between them, their spouses and their healthcare professionals?

Output: thoughts about dying

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not discussed between them, their spouses and their healthcare professionals?. ### Response: thoughts about dying.


Instruction: What did some report that they only thought would be deactivated in cases where it needed to be changed?

Output: a device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some report that they only thought would be deactivated in cases where it needed to be changed?. ### Response: a device.


Instruction: What was required if a patient had an infection or an MRI?

Output: the battery had run out

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was required if a patient had an infection or an MRI?. ### Response: the battery had run out.


Instruction: What did some patients feel their clinician may have told them in passing about?

Output: end of life care and deactivation issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some patients feel their clinician may have told them in passing about?. ### Response: end of life care and deactivation issues.


Instruction: What are the concerns about the coherence of the finding?

Output: minor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the concerns about the coherence of the finding?. ### Response: minor.


Instruction: What is the reason for the partial relevance of the contributing studies?

Output: outside of the UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reason for the partial relevance of the contributing studies?. ### Response: outside of the UK.


Instruction: The UK had minor concerns about inadequacy as the evidence provided what?

Output: reasonable depth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The UK had minor concerns about inadequacy as the evidence provided what?. ### Response: reasonable depth.


Instruction: There was a n overall judgement of low confidence in this sub-finding due to the concerns regarding the methodological limitations and what else?

Output: rele vance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There was a n overall judgement of low confidence in this sub-finding due to the concerns regarding the methodological limitations and what else?. ### Response: rele vance.


Instruction: What should be performed to assess the presence or absence of LA thrombus and to evaluate the severity of MR?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed to assess the presence or absence of LA thrombus and to evaluate the severity of MR?. ### Response: TEE.


Instruction: What is the initial di-agnostic test to determine the severity of the stenosis?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the initial di-agnostic test to determine the severity of the stenosis?. ### Response: TTE.


Instruction: What is TTE for patients with rheumatic MS?

Output: the initial di-agnostic test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TTE for patients with rheumatic MS?. ### Response: the initial di-agnostic test.


Instruction: Stages of MSStage Definition Valve Anatomy Valve What?

Output: Hemodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stages of MSStage Definition Valve Anatomy Valve What?. ### Response: Hemodynamics.


Instruction: Doming during diastole Normal transmitral flow velocity None NoneB Progressive MS Rheumatic valve changes with commissural fusion and what?

Output: diastolic doming of the mitral valve leaflets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Doming during diastole Normal transmitral flow velocity None NoneB Progressive MS Rheumatic valve changes with commissural fusion and what?. ### Response: diastolic doming of the mitral valve leaflets.


Instruction: What is asymptomatic severe MSRheumatic valve changes with commissural fusion and diastolic doming of the mitral valve leaflets?

Output: Progressive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic severe MSRheumatic valve changes with commissural fusion and diastolic doming of the mitral valve leaflets?. ### Response: Progressive.


Instruction: PASP >50 mm HgNoneD Symptomatic severe MS Rheumatic valve changes with commissural fusion and diastolic doming of the mitral valve leafletsWhat should be obtained?

Output: Severe LA enlargement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PASP >50 mm HgNoneD Symptomatic severe MS Rheumatic valve changes with commissural fusion and diastolic doming of the mitral valve leafletsWhat should be obtained?. ### Response: Severe LA enlargement.


Instruction: Exercise toleranceExertional dyspneaThe transmitral mean pressure gradient should be obtained to further determine the hemodynamic effect of what?

Output: the MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise toleranceExertional dyspneaThe transmitral mean pressure gradient should be obtained to further determine the hemodynamic effect of what?. ### Response: the MS.


Instruction: What is usually >5 mm Hg to 10 mm hg in severe MS?

Output: transmitral mean pressure gradient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is usually >5 mm Hg to 10 mm hg in severe MS?. ### Response: transmitral mean pressure gradient.


Instruction: Because of the variability of the means pressure gradient with heart rate and forward flow, what is it?

Output: it has not been included in the criteria for severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Because of the variability of the means pressure gradient with heart rate and forward flow, what is it?. ### Response: it has not been included in the criteria for severity.


Instruction: What does LA indicate?

Output: left atrial; MS, mitral stenosis; and PASP , pulmonary artery systolic pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LA indicate?. ### Response: left atrial; MS, mitral stenosis; and PASP , pulmonary artery systolic pressure.


Instruction: What does MS mean?

Output: mitral stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MS mean?. ### Response: mitral stenosis.


Instruction: When was this document downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this document downloaded?. ### Response: April 28, 2023.


Instruction: What is a meta-analysis of car-diovascular outcomes trials comparing intensive versus moderate lipid lowering with statins after acute coronary syndromes?

Output: Meta-analysis of car-diovascular outcomes trials comparing intensive versus moderate statintherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of car-diovascular outcomes trials comparing intensive versus moderate lipid lowering with statins after acute coronary syndromes?. ### Response: Meta-analysis of car-diovascular outcomes trials comparing intensive versus moderate statintherapy.


Instruction: What does Zocor stand for?

Output: simvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Zocor stand for?. ### Response: simvastatin.


Instruction: What is the name of the drug that increases the risk of muscle damage?

Output: Zocor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that increases the risk of muscle damage?. ### Response: Zocor.


Instruction: When was the J Am Coll Cardiol 48:438-45.563?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 48:438-45.563?. ### Response: 2006.


Instruction: What is Simvastatin?

Output: Zocor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Simvastatin?. ### Response: Zocor.


Instruction: What is the name of the drug that increases the risk of muscle injury?

Output: Zocor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that increases the risk of muscle injury?. ### Response: Zocor.


Instruction: Where can you find Zocor?

Output: U.S. Department of Health and Human Services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find Zocor?. ### Response: U.S. Department of Health and Human Services.


Instruction: When is Zocor available?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is Zocor available?. ### Response: 2011.


Instruction: How is statin therapy associated with reduced cardiac mortality?

Output: after coronary artery bypassgraft surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is statin therapy associated with reduced cardiac mortality?. ### Response: after coronary artery bypassgraft surgery.


Instruction: What is the outcome of coronary artery bypassgraft surgery?

Output: reduced cardiac mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the outcome of coronary artery bypassgraft surgery?. ### Response: reduced cardiac mortality.


Instruction: What is statin therapy used for?

Output: reduced cardiac mortality after coronary artery bypassgraft surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is statin therapy used for?. ### Response: reduced cardiac mortality after coronary artery bypassgraft surgery.


Instruction: How does statin affect postoperative outcomes?

Output: protective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does statin affect postoperative outcomes?. ### Response: protective.


Instruction: What effect did statin therapy have on postoperative major adverse cardiacevents after coronary artery bypass surgery?

Output: Lipid-lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What effect did statin therapy have on postoperative major adverse cardiacevents after coronary artery bypass surgery?. ### Response: Lipid-lowering.


Instruction: When was the J Thorac Cardiovasc Surg.134:1143–9.568?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg.134:1143–9.568?. ### Response: 2007.


Instruction: Where was the Deleted in proof.570?

Output: proof.569

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the Deleted in proof.570?. ### Response: proof.569.


Instruction: What is the risk of atrial fibrillation following coronary artery bypass grafting?

Output: postoperative risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of atrial fibrillation following coronary artery bypass grafting?. ### Response: postoperative risk.


Instruction: What is atorvastatin for?

Output: Reductionof MYocardial Dysrhythmia After cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atorvastatin for?. ### Response: Reductionof MYocardial Dysrhythmia After cardiac surgery.


Instruction: When was the ARMYDA-3 study conducted?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ARMYDA-3 study conducted?. ### Response: 2004.


Instruction: Dysrhythmia After cardiac surgery) study. Circulation.2006;114:1455–61.573. Aboyans V, Labrousse L, Lacroix P, et al. Predictive factors of strokein patientsundergoing coronary bypass grafting: statins are what?

Output: protective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dysrhythmia After cardiac surgery) study. Circulation.2006;114:1455–61.573. Aboyans V, Labrousse L, Lacroix P, et al. Predictive factors of strokein patientsundergoing coronary bypass grafting: statins are what?. ### Response: protective.


Instruction: Preoperative use ofstatins is associated with reduced early delirium rates after what procedure?

Output: cardiacsurgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preoperative use ofstatins is associated with reduced early delirium rates after what procedure?. ### Response: cardiacsurgery.


Instruction: What is associated with reduced early delirium rates after cardiacsurgery?

Output: Preoperative use ofstatins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with reduced early delirium rates after cardiacsurgery?. ### Response: Preoperative use ofstatins.


Instruction: Anesthesiology. 2009;110:67–73.575 What is the renoprotective effect ofpreoperative statins in coronary artery bypass grafting?

Output: reduced cardiac mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anesthesiology. 2009;110:67–73.575 What is the renoprotective effect ofpreoperative statins in coronary artery bypass grafting?. ### Response: reduced cardiac mortality.


Instruction: What is the benefit of bypassing the closest to bring the patient to a higher level of stroke care?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of bypassing the closest to bring the patient to a higher level of stroke care?. ### Response: uncertain.


Instruction: What type of thrombectomy is an example of an IV alteplase-capable hospital?

Output: mechanical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of thrombectomy is an example of an IV alteplase-capable hospital?. ### Response: mechanical.


Instruction: What should be developed to facilitate rapid transport of patients potentially eligible for thrombectomy to the closest healthcare facilities?

Output: Effective prehospital procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be developed to facilitate rapid transport of patients potentially eligible for thrombectomy to the closest healthcare facilities?. ### Response: Effective prehospital procedures.


Instruction: What should patients who are ineligible for IV thrombolysis and have a strong probability of LVO stroke have?

Output: Effective prehospital procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients who are ineligible for IV thrombolysis and have a strong probability of LVO stroke have?. ### Response: Effective prehospital procedures.


Instruction: How many stroke severity scales have been published to facilitate transfer to endovascular centers?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many stroke severity scales have been published to facilitate transfer to endovascular centers?. ### Response: 6.


Instruction: The 2018 AHA systematic review on the accuracy of prediction instruments for diagnosing LVO in what setting?

Output: patients with suspected stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The 2018 AHA systematic review on the accuracy of prediction instruments for diagnosing LVO in what setting?. ### Response: patients with suspected stroke.


Instruction: What was the probability of LVO with a positive LVO prediction test?

Output: 50% to 60%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the probability of LVO with a positive LVO prediction test?. ### Response: 50% to 60%,.


Instruction: What percentage of patients with suspected stroke were likely to have LVO if a prediction test was positive?

Output: 50% to 60%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with suspected stroke were likely to have LVO if a prediction test was positive?. ### Response: 50% to 60%,.


Instruction: What percentage of those with a negative test may have an LVO?

Output: >10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of those with a negative test may have an LVO?. ### Response: >10%.


Instruction: What is needed to identify suspected stroke patients?

Output: effective tools

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to identify suspected stroke patients?. ### Response: effective tools.


Instruction: How were the scales originally derived?

Output: data sets of confirmed stroke cases or selected prehospital cases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the scales originally derived?. ### Response: data sets of confirmed stroke cases or selected prehospital cases.


Instruction: What does the Mission: Lifeline Severity-based Stroke Triage Algorithm for EMS40 recommend for prehospital patients with suspected LVO by a stroke severity scale?

Output: direct transport to a comprehensive stroke center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Mission: Lifeline Severity-based Stroke Triage Algorithm for EMS40 recommend for prehospital patients with suspected LVO by a stroke severity scale?. ### Response: direct transport to a comprehensive stroke center.


Instruction: What has been limited study of in the prehospital setting?

Output: their performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been limited study of in the prehospital setting?. ### Response: their performance.


Instruction: What does the Stroke Triage Algorithm for EMS40 recommend?

Output: direct transport to a comprehensive stroke center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Stroke Triage Algorithm for EMS40 recommend?. ### Response: direct transport to a comprehensive stroke center.


Instruction: How long is the travel time to a comprehensive stroke center compared to the closest primary stroke center or acute stroke ready hospital?

Output: <15 additional minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the travel time to a comprehensive stroke center compared to the closest primary stroke center or acute stroke ready hospital?. ### Response: <15 additional minutes.


Instruction: Why is bypass of a primary stroke center or acute stroke-ready hospital not justifiable?

Output: When several IV alteplase–capable hospital options exist within a defined geographic region

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is bypass of a primary stroke center or acute stroke-ready hospital not justifiable?. ### Response: When several IV alteplase–capable hospital options exist within a defined geographic region.


Instruction: What is the known impact of delays to IV alteplase on outcomes?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the known impact of delays to IV alteplase on outcomes?. ### Response: uncertain.


Instruction: What are the known impacts of delayed mechanical thrombectomy on outcome?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the known impacts of delayed mechanical thrombectomy on outcome?. ### Response: uncertain.


Instruction: How many weeks of ceftriaxone alone?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many weeks of ceftriaxone alone?. ### Response: 4 weeks.


Instruction: What has become an accepted practice for adult patients with infections other than endocarditis?

Output: once-daily dosing of gentamicin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has become an accepted practice for adult patients with infections other than endocarditis?. ### Response: once-daily dosing of gentamicin.


Instruction: How many studies have been published detailing the use of gentamicin?

Output: few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have been published detailing the use of gentamicin?. ### Response: few.


Instruction: What has been published about once-daily dosing of gentamicin in children?

Output: no studies describing outcomes after the use of single daily dosing of gentamicin for the treatment of IE in children have been published

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been published about once-daily dosing of gentamicin in children?. ### Response: no studies describing outcomes after the use of single daily dosing of gentamicin for the treatment of IE in children have been published.


Instruction: What are children with other than endocarditis treated for?

Output: streptococcal endocarditis in adults have been published. Several stud-ies have demonstrated the safety and efficacy of once-daily dosing of gentamicin in children with infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are children with other than endocarditis treated for?. ### Response: streptococcal endocarditis in adults have been published. Several stud-ies have demonstrated the safety and efficacy of once-daily dosing of gentamicin in children with infections.


Instruction: How many studies have been published describing outcomes after the use of single daily doses?

Output: no

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have been published describing outcomes after the use of single daily doses?. ### Response: no.


Instruction: Occasionally, what may be caused by IE?

Output: streptococci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Occasionally, what may be caused by IE?. ### Response: streptococci.


Instruction: What is the MIC of streptococci that are resistant to penicillin?

Output: between 0.1 and 0.5 μ g/mL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MIC of streptococci that are resistant to penicillin?. ### Response: between 0.1 and 0.5 μ g/mL.


Instruction: What is a treatment regimen of 4 weeks of penicillin, ampicillin, or both?

Output: ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a treatment regimen of 4 weeks of penicillin, ampicillin, or both?. ### Response: ceftriaxone.


Instruction: How many weeks of penicillin, ampicillin, or ceftriaxone combined with gentamicin for the first 2 weeks?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many weeks of penicillin, ampicillin, or ceftriaxone combined with gentamicin for the first 2 weeks?. ### Response: 4.


Instruction: Patients with IE caused by Abiotrophia, Granulicatella species, or streptococci should be treated with the antibiotic regimen listed for what?

Output: enterococci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with IE caused by Abiotrophia, Granulicatella species, or streptococci should be treated with the antibiotic regimen listed for what?. ### Response: enterococci.


Instruction: What should be treated with the antibiotic regimen listed for enterococci?

Output: Patients with IE caused by Abiotrophia, Granulicatella species, or streptococci with an MIC of >0.5 μ g of penicillin per milliliter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be treated with the antibiotic regimen listed for enterococci?. ### Response: Patients with IE caused by Abiotrophia, Granulicatella species, or streptococci with an MIC of >0.5 μ g of penicillin per milliliter.


Instruction: What is an effective substitute for -lactam antibiotic drugs?

Output: vancomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an effective substitute for -lactam antibiotic drugs?. ### Response: vancomycin.


Instruction: How long is genta-micin for?

Output: 4-week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is genta-micin for?. ### Response: 4-week.


Instruction: What should be exer-cised by obtaining blood levels of vancomycin and gentamicin as well as serum creatinine levels weekly?

Output: Caution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be exer-cised by obtaining blood levels of vancomycin and gentamicin as well as serum creatinine levels weekly?. ### Response: Caution.


Instruction: What account for 3% to 5% of cases in children?

Output: S pneumoniae

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What account for 3% to 5% of cases in children?. ### Response: S pneumoniae.


Instruction: Why has no optimal therapy been established for pneumococcal IE?

Output: the syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why has no optimal therapy been established for pneumococcal IE?. ### Response: the syndrome.


Instruction: When was a review published of pneumcocccal endocarditis published?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a review published of pneumcocccal endocarditis published?. ### Response: 2004.


Instruction: How many cases of IE were reported over a 10-year period at 8 children’s hospitals?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of IE were reported over a 10-year period at 8 children’s hospitals?. ### Response: 11.


Instruction: How many of the 11 children's hospitals survived to the time of discharge?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the 11 children's hospitals survived to the time of discharge?. ### Response: 10.


Instruction: What was the name of the drug that all of the isolates were susceptible to?

Output: ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the drug that all of the isolates were susceptible to?. ### Response: ceftriaxone.


Instruction: How long did it take for a child to survive to be discharged?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for a child to survive to be discharged?. ### Response: 10.


Instruction: What was the intermediate susceptibility to penicillin?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the intermediate susceptibility to penicillin?. ### Response: 1.


Instruction: How many patients received cefotaxime or ceftriaxone?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients received cefotaxime or ceftriaxone?. ### Response: 5.


Instruction: What did 1 patient receive?

Output: many different antibiotic drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did 1 patient receive?. ### Response: many different antibiotic drugs.


Instruction: Who died during cardiac surgery?

Output: One patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who died during cardiac surgery?. ### Response: One patient.


Instruction: What antibiotics were given for a pneumococ-cal isolate intermediately susceptible to penicillin?

Output: vancomycin and cefotaxime

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What antibiotics were given for a pneumococ-cal isolate intermediately susceptible to penicillin?. ### Response: vancomycin and cefotaxime.


Instruction: What was the consensus of the writing group that consultation with an infectious disease spe-cialist should be considered for all children with IE?

Output: It was the consensus of the writing group that consultation with an infectious disease spe-cialist should be considered for all children with IE but espe-cially for IE caused by S pneumoniae that is not susceptible to penicillin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the consensus of the writing group that consultation with an infectious disease spe-cialist should be considered for all children with IE?. ### Response: It was the consensus of the writing group that consultation with an infectious disease spe-cialist should be considered for all children with IE but espe-cially for IE caused by S pneumoniae that is not susceptible to penicillin.


Instruction: What should be considered for all children with IE?

Output: consultation with an infectious disease spe-cialist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered for all children with IE?. ### Response: consultation with an infectious disease spe-cialist.


Instruction: What is S pneumoniae not susceptible to?

Output: penicillin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is S pneumoniae not susceptible to?. ### Response: penicillin.


Instruction: How long is a regimen of intravenous aqueous crysotherapy recommended?

Output: 4-week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is a regimen of intravenous aqueous crysotherapy recommended?. ### Response: 4-week.


Instruction: How many reviewers reviewed Fihn et al 2014 Stable Ischemic Heart Disease Focused Update 1753?

Output: 1753

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many reviewers reviewed Fihn et al 2014 Stable Ischemic Heart Disease Focused Update 1753?. ### Response: 1753.


Instruction: What is the ACC Imaging Section Leadership Council?

Output: Stable Ischemic Heart Disease Focused Update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC Imaging Section Leadership Council?. ### Response: Stable Ischemic Heart Disease Focused Update.


Instruction: Who approved the publication of this document?

Output: the govern-ing bodies of the ACC, AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who approved the publication of this document?. ### Response: the govern-ing bodies of the ACC, AHA.


Instruction: What was collected and distributed to the writing group?

Output: Reviewers’ RWI information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was collected and distributed to the writing group?. ### Response: Reviewers’ RWI information.


Instruction: Who approved this document for publication?

Output: the govern-ing bodies of the ACC, AHA, and by other partner organiza-tions, the AATS, PCNA, SCAI, and STS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who approved this document for publication?. ### Response: the govern-ing bodies of the ACC, AHA, and by other partner organiza-tions, the AATS, PCNA, SCAI, and STS.


Instruction: What is useful in patients with suspected SIHD?

Output: Coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful in patients with suspected SIHD?. ### Response: Coronary angiography.


Instruction: What type of testing is recommended for Diagnosis of Coronary Artery Disease?

Output: Invasive Testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of testing is recommended for Diagnosis of Coronary Artery Disease?. ### Response: Invasive Testing.


Instruction: What is useful in patients with SIHD who have unacceptable ischemic symp-toms despite GDMT?

Output: Coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful in patients with SIHD who have unacceptable ischemic symp-toms despite GDMT?. ### Response: Coronary angiography.


Instruction: What is reasonable to define the extent and severity of coronary artery disease?

Output: ary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to define the extent and severity of coronary artery disease?. ### Response: ary angiography.


Instruction: What does CAD stand for?

Output: coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CAD stand for?. ### Response: coronary artery disease.


Instruction: What is the level of evidence for coronary angiography?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for coronary angiography?. ### Response: C.


Instruction: What is reasonable in patients with suspected symptomatic SIHD who cannot undergo diagnostic stress testing or have indeterminate or nondiagnostic stress tests?

Output: Coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in patients with suspected symptomatic SIHD who cannot undergo diagnostic stress testing or have indeterminate or nondiagnostic stress tests?. ### Response: Coronary angiography.


Instruction: What type of angiography might be considered in patients with stress test results of acceptable quality that do not suggest the presence of CAD?

Output: Coronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of angiography might be considered in patients with stress test results of acceptable quality that do not suggest the presence of CAD?. ### Response: Coronary.


Instruction: What is the likelihood that the findings will result in important changes to therapy?

Output: high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the likelihood that the findings will result in important changes to therapy?. ### Response: high.


Instruction: What was added to the 2014 SIHD focused update to fill a gap in the 2012 SIHD guideline?

Output: Coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was added to the 2014 SIHD focused update to fill a gap in the 2012 SIHD guideline?. ### Response: Coronary angiography.


Instruction: What does Section 3.3 of the 2012 SIHD full-text guideline address?

Output: iography for risk stratification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Section 3.3 of the 2012 SIHD full-text guideline address?. ### Response: iography for risk stratification.


Instruction: What is the role of coronary angiography for the diagnosis of in SIHD patients?

Output: useful

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of coronary angiography for the diagnosis of in SIHD patients?. ### Response: useful.


Instruction: What are patients with heart failure and/or reduced ejection fractions considered to have?

Output: Patients with heart failure and/or reduced ejection fraction13•	Patients who have experienced sudden cardiac death or sustained ventricular arrhythmia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with heart failure and/or reduced ejection fractions considered to have?. ### Response: Patients with heart failure and/or reduced ejection fraction13•	Patients who have experienced sudden cardiac death or sustained ventricular arrhythmia.


Instruction: What do patients who have experienced sudden cardiac death or sustained ventricular arrhythmia suffer from?

Output: Patients with heart failure and/or reduced ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients who have experienced sudden cardiac death or sustained ventricular arrhythmia suffer from?. ### Response: Patients with heart failure and/or reduced ejection fraction.


Instruction: Patients undergoing preoperative cardiovascular evalu-ation for noncardiac surgery (including solid organ transplantation)15

Output: Stable Ischemic Heart Disease Focused Update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients undergoing preoperative cardiovascular evalu-ation for noncardiac surgery (including solid organ transplantation)15. ### Response: Stable Ischemic Heart Disease Focused Update.


Instruction: What year did N Engl J Med publish 340:381–3.470?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med publish 340:381–3.470?. ### Response: 1999.


Instruction: What is the name of the imaging technique used to detect papillary muscle infarction in patients with ST-segment elevation myocardial infarct?

Output: late gadolinium-enhanced magnetic resonance imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the imaging technique used to detect papillary muscle infarction in patients with ST-segment elevation myocardial infarct?. ### Response: late gadolinium-enhanced magnetic resonance imaging.


Instruction: What is Chronic Heart Failure?

Output: Chroni c Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chronic Heart Failure?. ### Response: Chroni c Heart Failure.


Instruction: What is NICE 2018 Subject to?

Output: Notice of rights

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018 Subject to?. ### Response: Notice of rights.


Instruction: How many participants did the study have?

Output: 136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants did the study have?. ### Response: 136.


Instruction: Evidence (GRADE) Anticipated absolute effects Risk with medical therapy Risk difference with CABG bias, imprecision (a) Downgraded by 1 increment if majority of the evidence was rated high risk of bias, downgrade by 2 increments?

Output: bias, downgraded by 2 increments if majority of the evidence was rated  very high risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence (GRADE) Anticipated absolute effects Risk with medical therapy Risk difference with CABG bias, imprecision (a) Downgraded by 1 increment if majority of the evidence was rated high risk of bias, downgrade by 2 increments?. ### Response: bias, downgraded by 2 increments if majority of the evidence was rated  very high risk of bias.


Instruction: How many increments are downgraded if the majority of the evidence was rated very high risk of bias?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments are downgraded if the majority of the evidence was rated very high risk of bias?. ### Response: 2.


Instruction: How much increments do downgrades occur when the confidence interval cross ed one MID?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increments do downgrades occur when the confidence interval cross ed one MID?. ### Response: 2.


Instruction: What happens if the confidence interval cross ed both MIDs?

Output: downgraded by 2 increments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What happens if the confidence interval cross ed both MIDs?. ### Response: downgraded by 2 increments.


Instruction: Why is the outcome downgraded by 1 increment?

Output: indirectness of the outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the outcome downgraded by 1 increment?. ### Response: indirectness of the outcome.


Instruction: What is the intention to revascularise with CABG?

Output: PCI) versus medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the intention to revascularise with CABG?. ### Response: PCI) versus medical therapy.


Instruction: Invasive strategy versus medical therapy Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE)

Output: medi cal therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Invasive strategy versus medical therapy Outcomes No of Participants (studies) Follow up Quality of the evidence (GRADE). ### Response: medi cal therapy.


Instruction: What is the term for Quality of the evidence?

Output: GRADE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for Quality of the evidence?. ### Response: GRADE.


Instruction: What percentage of the CI is for anticipated absolute effects?

Output: 95%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the CI is for anticipated absolute effects?. ### Response: 95%.


Instruction: How long is the all-cause mortality in one study?

Output: 4.9 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the all-cause mortality in one study?. ### Response: 4.9 years.


Instruction: Why is 4.9 years VERY LOWa,b due to risk of bias, imprecision RR 1.04?

Output: The mean quality of life – EQ-5D at 6 months in the intervention groups was  0.02 lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is 4.9 years VERY LOWa,b due to risk of bias, imprecision RR 1.04?. ### Response: The mean quality of life – EQ-5D at 6 months in the intervention groups was  0.02 lower.


Instruction: What is the EQ-5D Scale from: 0 to 1.136 (1.67 to 1.61)?

Output: Quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the EQ-5D Scale from: 0 to 1.136 (1.67 to 1.61)?. ### Response: Quality of life.


Instruction: What is the EQ-5D Scale from: 0 to 1.136 (1 study) 6 months  VERYLOWa,b due to risk of bias, imprecision c The mean quality of life – EQ5D at 6 months in the intervention groups was 0.02 lower (0.14 lower)?

Output: Quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the EQ-5D Scale from: 0 to 1.136 (1 study) 6 months  VERYLOWa,b due to risk of bias, imprecision c The mean quality of life – EQ5D at 6 months in the intervention groups was 0.02 lower (0.14 lower)?. ### Response: Quality of life.


Instruction: What was the difference between the intervention groups?

Output: 0.02 lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between the intervention groups?. ### Response: 0.02 lower.


Instruction: What is the MLWHF Scale from: 0 to 105?

Output: Quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MLWHF Scale from: 0 to 105?. ### Response: Quality of life.


Instruction: How long did the study last?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: 6 months.


Instruction: Why was the mean of the study LOW?

Output: ris k of bias , imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the mean of the study LOW?. ### Response: ris k of bias , imprecision.


Instruction: What was the mean quality of life - MLWHF at 6 months in the intervention groups?

Output: 3.9 low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean quality of life - MLWHF at 6 months in the intervention groups?. ### Response: 3.9 low.


Instruction: What was downgraded by 1 increment if majority of the evidence was rated high risk of bias?

Output: confidence interval cross ed one MID

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was downgraded by 1 increment if majority of the evidence was rated high risk of bias?. ### Response: confidence interval cross ed one MID.


Instruction: What percentage of the evidence was rated high risk of bias?

Output: majority

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the evidence was rated high risk of bias?. ### Response: majority.


Instruction: How many increments were downgraded if the majority of evidence were rated very high risk?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were downgraded if the majority of evidence were rated very high risk?. ### Response: 2.


Instruction: What percentage was upgraded by 1 increment when the confidence interval crossed one MID?

Output: 0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage was upgraded by 1 increment when the confidence interval crossed one MID?. ### Response: 0.


Instruction: Downgraded by how many increments if the confidence interval cross ed both MIDs?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Downgraded by how many increments if the confidence interval cross ed both MIDs?. ### Response: 2.


Instruction: Unable to calculate as the study o nly reported what?

Output: the ove rall mean difference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Unable to calculate as the study o nly reported what?. ### Response: the ove rall mean difference.


Instruction: What is the acronym for American College of Cardiology Foundation?

Output: ACCF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American College of Cardiology Foundation?. ### Response: ACCF.


Instruction: What does AHA stand for?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AHA stand for?. ### Response: American Heart Association.


Instruction: How does FMC stand for first medical contact?

Output: ACCF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does FMC stand for first medical contact?. ### Response: ACCF.


Instruction: Where can you find the appendix A?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the appendix A?. ### Response: http://ahajournals.org.


Instruction: What is a scienti fic state-ment from the American Heart Association and theHeart Failure Society of America?

Output: diabetes mellitus and heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scienti fic state-ment from the American Heart Association and theHeart Failure Society of America?. ### Response: diabetes mellitus and heart failure.


Instruction: What does this statement not represent an update of?

Output: 2017 ACC/AHA/HFSAheart failure guideline update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does this statement not represent an update of?. ### Response: 2017 ACC/AHA/HFSAheart failure guideline update.


Instruction: What type of diabetes mellitus is associated with heart failure?

Output: Type2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes mellitus is associated with heart failure?. ### Response: Type2.


Instruction: What is the name of the association that studies the relationship between heart failure and type 2 diabetes?

Output: Heart Failure Association of the Euro-pean Society of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the association that studies the relationship between heart failure and type 2 diabetes?. ### Response: Heart Failure Association of the Euro-pean Society of Cardiology.


Instruction: When did the Eur J Heart Fail issue 20:853–72.154?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Eur J Heart Fail issue 20:853–72.154?. ### Response: 2018.


Instruction: What is the name of the disease that causes death in type 2 diabetes?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes death in type 2 diabetes?. ### Response: heart failure.


Instruction: What are the names of the diseases that cause death in Type 2diabetes?

Output: diabetes mellitus and heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the diseases that cause death in Type 2diabetes?. ### Response: diabetes mellitus and heart failure.


Instruction: In what year was the N Engl J Med published?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the N Engl J Med published?. ### Response: 2018.


Instruction: What is Dapagli flozinand cardiovascular outcomes in type 2 diabetes?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Dapagli flozinand cardiovascular outcomes in type 2 diabetes?. ### Response: mortality.


Instruction: What is the 2019 AHA/ACC/HRS focused update of the 2014?

Output: guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2019 AHA/ACC/HRS focused update of the 2014?. ### Response: guideline.


Instruction: What year did the AHA/ACC/HRSguideline for the management of patients with atrialfibrillation come out?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the AHA/ACC/HRSguideline for the management of patients with atrialfibrillation come out?. ### Response: 2014.


Instruction: What group did the Task Force on Clinical Practice Guidelines work with?

Output: American College ofCardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group did the Task Force on Clinical Practice Guidelines work with?. ### Response: American College ofCardiology/American Heart Association.


Instruction: What is a 2014 AHA/ACC/HRS guideline for the management of patientswith atrial fibrillation?

Output: American College of Cardi-ology/American Heart Association Task Force on Clin-ical Practice Guidelines and the Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 2014 AHA/ACC/HRS guideline for the management of patientswith atrial fibrillation?. ### Response: American College of Cardi-ology/American Heart Association Task Force on Clin-ical Practice Guidelines and the Heart Rhythm Society.


Instruction: What is the name of the Task Forceon Practice Guidelines and the Heart Rhythm Society?

Output: American College of Cardi-ology/American Heart Association Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Forceon Practice Guidelines and the Heart Rhythm Society?. ### Response: American College of Cardi-ology/American Heart Association Task Force.


Instruction: When did Nishimura RA, Otto CM, Bonow CM write a paper?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Nishimura RA, Otto CM, Bonow CM write a paper?. ### Response: 2017.


Instruction: What was the 2014 AHA/ACCguideline for the management of patients with valvularheart disease a report of the American College ofCardiology/American Heart Association Task Force onClinical Practice Guidelines?

Output: 2017AHA/ACC focused update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2014 AHA/ACCguideline for the management of patients with valvularheart disease a report of the American College ofCardiology/American Heart Association Task Force onClinical Practice Guidelines?. ### Response: 2017AHA/ACC focused update.


Instruction: What is the J Am Coll Cardiol. 2017:70:252–89.161?

Output: 2017AHA/ACC focused update of the 2014 AHA/ACCguideline for the management of patients with valvularheart disease: a report of the American College ofCardiology/American Heart Association Task Force onClinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2017:70:252–89.161?. ### Response: 2017AHA/ACC focused update of the 2014 AHA/ACCguideline for the management of patients with valvularheart disease: a report of the American College ofCardiology/American Heart Association Task Force onClinical Practice Guidelines.


Instruction: What year did the AmericanCollege of Cardiology/American Heart Association TaskForce on Practice Guidelines publish a report?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the AmericanCollege of Cardiology/American Heart Association TaskForce on Practice Guidelines publish a report?. ### Response: 2017.


Instruction: What is the name of the report that was released in 2014?

Output: American College ofCardiology/American Heart Association Task Force onClinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the report that was released in 2014?. ### Response: American College ofCardiology/American Heart Association Task Force onClinical Practice Guidelines.


Instruction: How many patients were evaluated in 2014 for valvular heart disease?

Output: 64:e1 –76.160

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were evaluated in 2014 for valvular heart disease?. ### Response: 64:e1 –76.160.


Instruction: What is the name of the committee that reviewed the 2017 ACC expert consensus on management of mitralregurgitation?

Output: American College ofCardiology Solution Set Oversight Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that reviewed the 2017 ACC expert consensus on management of mitralregurgitation?. ### Response: American College ofCardiology Solution Set Oversight Committee.


Instruction: When will the J AmColl Cardiol be 75?

Output: 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the J AmColl Cardiol be 75?. ### Response: 2020.


Instruction: What is the name of the guideline for the prevention, detection,evaluation and management of high blood pressure in adults?

Output: 2017ACC/AHA/AAPA/ABC/ACPM /AGS/APhA/ASH/ASPC/NMA/PCNA guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for the prevention, detection,evaluation and management of high blood pressure in adults?. ### Response: 2017ACC/AHA/AAPA/ABC/ACPM /AGS/APhA/ASH/ASPC/NMA/PCNA guideline.


Instruction: What is high blood pres-sure in adults?

Output: prevention, detection,evaluation, and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is high blood pres-sure in adults?. ### Response: prevention, detection,evaluation, and management.


Instruction: What is a report of the American College of Physicians?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Physicians?. ### Response: 2019.


Instruction: HBPM may help to improve what?

Output: patient motivation and adherence to treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HBPM may help to improve what?. ### Response: patient motivation and adherence to treatment.


Instruction: What is strong evidence that home BP measurements are predictive of?

Output: long-term adverse clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is strong evidence that home BP measurements are predictive of?. ### Response: long-term adverse clinical outcomes.


Instruction: What can HBPM help to improve?

Output: patient motivation and adherence to treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can HBPM help to improve?. ### Response: patient motivation and adherence to treatment.


Instruction: What can be used to identify patients with masked uncontrolled hypertension?

Output: HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to identify patients with masked uncontrolled hypertension?. ### Response: HBPM.


Instruction: What may require additional equipment, space, time, training, and/or change in culture, habits, or policies?

Output: The use of standardized of ﬁce measurements for BPmanagement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may require additional equipment, space, time, training, and/or change in culture, habits, or policies?. ### Response: The use of standardized of ﬁce measurements for BPmanagement.


Instruction: Practitioners would benefit from under-standing what?

Output: the guidelines and the underlying data and rationale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Practitioners would benefit from under-standing what?. ### Response: the guidelines and the underlying data and rationale.


Instruction: What is essential for shared decision-making with individual patients?

Output: The practitioners should provide general information andindividualized considerations of the pros and cons of thetreatment option

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is essential for shared decision-making with individual patients?. ### Response: The practitioners should provide general information andindividualized considerations of the pros and cons of thetreatment option.


Instruction: Who should provide general information andindividualized consideration of the pros and cons of thetreatment option?

Output: The practitioners

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should provide general information andindividualized consideration of the pros and cons of thetreatment option?. ### Response: The practitioners.


Instruction: What are the pros and cons of thetreatment option?

Output: more certain in some groups (e.g., those whowould have been eligible for SPRINT) and less certain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the pros and cons of thetreatment option?. ### Response: more certain in some groups (e.g., those whowould have been eligible for SPRINT) and less certain.


Instruction: What is the evidence for intensiveSBP targets less certain in some groups?

Output: proteinuria, diabetes, or older age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the evidence for intensiveSBP targets less certain in some groups?. ### Response: proteinuria, diabetes, or older age.


Instruction: People with diabetes, advanced CKD witheGFR30 ml/min per 1.73 m2, older adults aged >90 years and those with diabetes have what?

Output: severe hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People with diabetes, advanced CKD witheGFR30 ml/min per 1.73 m2, older adults aged >90 years and those with diabetes have what?. ### Response: severe hypertension.


Instruction: How many m2 of older adults have hypertension?

Output: >90 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many m2 of older adults have hypertension?. ### Response: >90 years.


Instruction: What does the recommendation state that clinicians should target?

Output: an SBP <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the recommendation state that clinicians should target?. ### Response: an SBP <120 mm Hg.


Instruction: How many antihypertensive drugs do older adults take?

Output: >4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many antihypertensive drugs do older adults take?. ### Response: >4.


Instruction: What percentage of patients with CKD will have a SBP >120 mm Hg at any one time?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with CKD will have a SBP >120 mm Hg at any one time?. ### Response: 50%.


Instruction: What would a more stringent recommendation be that all patients should achieve?

Output: an SBP <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would a more stringent recommendation be that all patients should achieve?. ### Response: an SBP <120 mm Hg.


Instruction: What would require aneven lower target or threshold for intervention?

Output: all patientsshould achieve an SBP <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would require aneven lower target or threshold for intervention?. ### Response: all patientsshould achieve an SBP <120 mm Hg.


Instruction: What would gobeyond the available evidence?

Output: adoption of this more stringent recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would gobeyond the available evidence?. ### Response: adoption of this more stringent recommendation.


Instruction: The mean achieved SBP was what?

Output: 121.4 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The mean achieved SBP was what?. ### Response: 121.4 mm Hg.


Instruction: What replaces the target recommendations from Chapters 3 and 4 of the KDIGO 2012 recommenda-tion on BP management in CKD?

Output: SPRINT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What replaces the target recommendations from Chapters 3 and 4 of the KDIGO 2012 recommenda-tion on BP management in CKD?. ### Response: SPRINT.


Instruction: What are the most important differences?

Output: the adoption of standardized of ﬁcemeasurement as the preferred technique

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the most important differences?. ### Response: the adoption of standardized of ﬁcemeasurement as the preferred technique.


Instruction: What is the current guideline only an SBP target and not a DBP target?

Output: seebelow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current guideline only an SBP target and not a DBP target?. ### Response: seebelow.


Instruction: The recommendation of standardized of fice measurement is what?

Output: the preferred technique

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The recommendation of standardized of fice measurement is what?. ### Response: the preferred technique.


Instruction: What is e570S Antithrombotic Therapy for Atrial Fibrillation?

Output: Thromboembolic complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is e570S Antithrombotic Therapy for Atrial Fibrillation?. ### Response: Thromboembolic complications.


Instruction: What is Petersen's specialty?

Output: Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Petersen's specialty?. ### Response: Stroke.


Instruction: How many strokes were there in 1990?

Output: 4 - 13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 1990?. ### Response: 4 - 13.


Instruction: How long did the Framingham Study follow up on lone atrial fibrillation?

Output: 30-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Framingham Study follow up on lone atrial fibrillation?. ### Response: 30-year.


Instruction: What study followed atrial fibrillation for 30 years?

Output: Framingham Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study followed atrial fibrillation for 30 years?. ### Response: Framingham Study.


Instruction: How long did the Framingham Study follow-up?

Output: 30-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Framingham Study follow-up?. ### Response: 30-year.


Instruction: When was the JAMA published?

Output: 1985

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 1985.


Instruction: What type of atrial fibrillation is a common cause of death?

Output: nonvalvular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of atrial fibrillation is a common cause of death?. ### Response: nonvalvular.


Instruction: What is the name of the study that focuses on the prevention of stroke?

Output: The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that focuses on the prevention of stroke?. ### Response: The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography.


Instruction: How many people died from a stroke in the United States?

Output: 3449

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people died from a stroke in the United States?. ### Response: 3449.


Instruction: What is the incidence of intermittent atrial fibrillation?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence of intermittent atrial fibrillation?. ### Response: stroke.


Instruction: What are the predictors during aspirin therapy?

Output: Stroke with intermittent atrial ﬁ brillation: incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the predictors during aspirin therapy?. ### Response: Stroke with intermittent atrial ﬁ brillation: incidence.


Instruction: How many ( 1 ): 183 - 187 in 2000?

Output: 35

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 1 ): 183 - 187 in 2000?. ### Response: 35.


Instruction: What is the name of the ACTIVE W Investigators?

Output: Hohnloser

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACTIVE W Investigators?. ### Response: Hohnloser.


Instruction: What type of stroke is more common in paroxysmal than sustained atrial fibrillation?

Output: brillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stroke is more common in paroxysmal than sustained atrial fibrillation?. ### Response: brillation.


Instruction: What is an ACTIVE W Substudy?

Output: Incidence of stroke in paroxysmal versus sustained atrial ﬁ  brillation in patients taking oral antico-agulation or combined antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ACTIVE W Substudy?. ### Response: Incidence of stroke in paroxysmal versus sustained atrial ﬁ  brillation in patients taking oral antico-agulation or combined antiplatelet therapy.


Instruction: What is a Indepen-dent predictor of stroke risk in atrial fibrillation?

Output: aspirin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Indepen-dent predictor of stroke risk in atrial fibrillation?. ### Response: aspirin therapy.


Instruction: Atrial Fibrillation Working Group: Indepen-dent predictors of stroke in patients with atrial fi llation: a systematic review?

Output: Stroke Risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial Fibrillation Working Group: Indepen-dent predictors of stroke in patients with atrial fi llation: a systematic review?. ### Response: Stroke Risk.


Instruction: What is the National Clinical Guideline for Management of Atrial Fibrillation in Primary and Secondary Care?

Output: Guideline Development Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the National Clinical Guideline for Management of Atrial Fibrillation in Primary and Secondary Care?. ### Response: Guideline Development Group.


Instruction: What is the name of the systematic review of stroke risk fac-tors, risk stratifi cation schema and cost effectiveness data?

Output: Thromb Haemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of stroke risk fac-tors, risk stratifi cation schema and cost effectiveness data?. ### Response: Thromb Haemost.


Instruction: When was Thromb Haemost published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Thromb Haemost published?. ### Response: 2008.


Instruction: What is the average age of a patient with atrial fibrillation?

Output: 36 - 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average age of a patient with atrial fibrillation?. ### Response: 36 - 40.


Instruction: What does age have on stroke prevention?

Output: Effect of age on stroke prevention therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does age have on stroke prevention?. ### Response: Effect of age on stroke prevention therapy.


Instruction: What is the name of the atrial fi brillation investigators?

Output: The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the atrial fi brillation investigators?. ### Response: The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography.


Instruction: How many strokes were there in 2009?

Output: 1410 - 1416

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 2009?. ### Response: 1410 - 1416.