Instruction: What is a measure of the effects of an illness to see how it affects someone's day-to-day life?

Output: Health -related quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a measure of the effects of an illness to see how it affects someone's day-to-day life?. ### Response: Health -related quality of life.


Instruction: What term is used in meta -analyses and systematic reviews to describe when the results are homogeneous?

Output: PICO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What term is used in meta -analyses and systematic reviews to describe when the results are homogeneous?. ### Response: PICO.


Instruction: What do systematic reviews describe when the results of a test or treatment differ significantly in different studies?

Output: Heterogeneity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do systematic reviews describe when the results of a test or treatment differ significantly in different studies?. ### Response: Heterogeneity.


Instruction: What may occur because of differences in the populations studied?

Output: differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may occur because of differences in the populations studied?. ### Response: differences.


Instruction: What is the opposite of homogeneity?

Output: Imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the opposite of homogeneity?. ### Response: Imprecision.


Instruction: What results are imprecise when studies include relatively few patients and few events?

Output: Imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What results are imprecise when studies include relatively few patients and few events?. ### Response: Imprecision.


Instruction: What is included criteria used to decide which studies should be considered as potential sources of evidence?

Output: Inclusion criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included criteria used to decide which studies should be considered as potential sources of evidence?. ### Response: Inclusion criteria.


Instruction: What is an analysis of additional costs and additional clinical outcomes with different interventions?

Output: Incremental analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an analysis of additional costs and additional clinical outcomes with different interventions?. ### Response: Incremental analysis.


Instruction: What is ICER?

Output: Incremental cost -effectiveness ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ICER?. ### Response: Incremental cost -effectiveness ratio.


Instruction: What is the difference in the m ean costs in the population of interest divided by?

Output: differences in the mean outcomes in the population of interest for one treatment compared with another

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference in the m ean costs in the population of interest divided by?. ### Response: differences in the mean outcomes in the population of interest for one treatment compared with another.


Instruction: How are the m ean costs in the population of interest divided?

Output: differences in the mean outcomes in the population of interest for one treatment compared with another

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the m ean costs in the population of interest divided?. ### Response: differences in the mean outcomes in the population of interest for one treatment compared with another.


Instruction: What is the value of an intervention net of it s cost compared with its cost?

Output: Incremental net benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of an intervention net of it s cost compared with its cost?. ### Response: Incremental net benefit.


Instruction: How can the INB be calculated for a given cost -effectiveness threshold?

Output: If the threshold is £20,000 per QALY gained then the INB is calculated as: (£20,000 × QALYs gained) − Incremental cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can the INB be calculated for a given cost -effectiveness threshold?. ### Response: If the threshold is £20,000 per QALY gained then the INB is calculated as: (£20,000 × QALYs gained) − Incremental cost.


Instruction: What is the threshold for the cost to be effective?

Output: £20,000 per QALY gained

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the threshold for the cost to be effective?. ### Response: £20,000 per QALY gained.


Instruction: How much does the threshold cost per QALY?

Output: £20,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does the threshold cost per QALY?. ### Response: £20,000.


Instruction: How much money does it cost to gain QALYs in a clinical trial?

Output: £20,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much money does it cost to gain QALYs in a clinical trial?. ### Response: £20,000.


Instruction: What is indirectness?

Output: The available evidence is different to the review question being addressed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indirectness?. ### Response: The available evidence is different to the review question being addressed.


Instruction: How is the available evidence different from the review question being addressed?

Output: Indirectness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the available evidence different from the review question being addressed?. ### Response: Indirectness.


Instruction: PICO stands for what?

Output: population, intervention, comparison and outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PICO stands for what?. ### Response: population, intervention, comparison and outcome.


Instruction: What type of analyses are often used to assess clintical trials?

Output: Intention -to-treat analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of analyses are often used to assess clintical trials?. ### Response: Intention -to-treat analysis.


Instruction: What group of people are randomly allocated to?

Output: Intention -to-treat analysis (ITT)  An assessment of the people taking part in a clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group of people are randomly allocated to?. ### Response: Intention -to-treat analysis (ITT)  An assessment of the people taking part in a clinical trial.


Instruction: Intention-to-treat analyses are often used to assess clin ical effectiveness because they mirror what?

Output: actual practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Intention-to-treat analyses are often used to assess clin ical effectiveness because they mirror what?. ### Response: actual practice.


Instruction: In medical terms, what could be an intervention?

Output: drug treatment, surgic al procedure, diagnostic or psychological therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In medical terms, what could be an intervention?. ### Response: drug treatment, surgic al procedure, diagnostic or psychological therapy.


Instruction: What is an example of a public health intervention?

Output: action to help someone to be physically active or to eat a more healthy diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a public health intervention?. ### Response: action to help someone to be physically active or to eat a more healthy diet.


Instruction: What are some examples of public health interventions?

Output: action to help someone to be physically active or to eat a more healthy diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some examples of public health interventions?. ### Response: action to help someone to be physically active or to eat a more healthy diet.


Instruction: What are measures to lessen the risk of swelling and close monitoring of the patient for signs of neurological worsening during the first days after stroke recommended?

Output: Early transfer of patients at risk for malignant brain swelling to an institution with appropriate neurosurgical expertise should be considered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are measures to lessen the risk of swelling and close monitoring of the patient for signs of neurological worsening during the first days after stroke recommended?. ### Response: Early transfer of patients at risk for malignant brain swelling to an institution with appropriate neurosurgical expertise should be considered.


Instruction: What should be considered when transferring patients at risk for malignant brain swelling to an institution with appropriate neurosurgical expertise?

Output: Early transfer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered when transferring patients at risk for malignant brain swelling to an institution with appropriate neurosurgical expertise?. ### Response: Early transfer.


Instruction: Who should be considered for neurosurgical expertise?

Output: Early transfer of patients at risk for malignant brain swelling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should be considered for neurosurgical expertise?. ### Response: Early transfer of patients at risk for malignant brain swelling.


Instruction: Why was the C-LDRecommendation reworded?

Output: for clarity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the C-LDRecommendation reworded?. ### Response: for clarity.


Instruction: What was revised for brevity and consistency?

Output: C-LDRecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was revised for brevity and consistency?. ### Response: C-LDRecommendation.


Instruction: What is reasonable for patients with clinical deterioration from brain swelling associated with cerebral infarction?

Output: Use of osmotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for patients with clinical deterioration from brain swelling associated with cerebral infarction?. ### Response: Use of osmotic therapy.


Instruction: What was reworded for clarity from 2014 Brain Swelling?

Output: C-LDRecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reworded for clarity from 2014 Brain Swelling?. ### Response: C-LDRecommendation.


Instruction: What is a reasonable treatment for patients with acute severe neurological decline from brain swelling?

Output: Use of brief moderate hyperventilation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable treatment for patients with acute severe neurological decline from brain swelling?. ### Response: Use of brief moderate hyperventilation.


Instruction: How long did a single nonrandomized study of 3 days of sustained hyperventilation last?

Output: 5 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did a single nonrandomized study of 3 days of sustained hyperventilation last?. ### Response: 5 days.


Instruction: What did a single nonrandomized study of 3 days of sustained hyperventilation in AIS show no difference in?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a single nonrandomized study of 3 days of sustained hyperventilation in AIS show no difference in?. ### Response: mortality.


Instruction: What was the purpose of the study?

Output: to investigate physiological changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the purpose of the study?. ### Response: to investigate physiological changes.


Instruction: How long did the study last?

Output: 3 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: 3 days.


Instruction: Whose data show a rapid reduction in intracranial pressure?

Output: patients with traumatic brain injury

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Whose data show a rapid reduction in intracranial pressure?. ### Response: patients with traumatic brain injury.


Instruction: What did brain injury show a rapid reduction in?

Output: intracranial pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did brain injury show a rapid reduction in?. ### Response: intracranial pressure.


Instruction: What did return to baseline over the next few hours?

Output: intracranial pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did return to baseline over the next few hours?. ### Response: intracranial pressure.


Instruction: The only RCT of sustained hyperventilation in traumatic brain injury demonstrated that prophylactic hyperventillation for 5 days was associated with worse outcomes?

Output: 285

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The only RCT of sustained hyperventilation in traumatic brain injury demonstrated that prophylactic hyperventillation for 5 days was associated with worse outcomes?. ### Response: 285.


Instruction: What are not recommended in the setting of ischemic cerebral or cerebellar swelling?

Output: Hypothermia or barbiturates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are not recommended in the setting of ischemic cerebral or cerebellar swelling?. ### Response: Hypothermia or barbiturates.


Instruction: What was revised from 2014 Brain Swelling?

Output: LOE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was revised from 2014 Brain Swelling?. ### Response: LOE.


Instruction: How was COR amended to conform with ACC/AHA 2015 Recommendation Classification System?

Output: LOE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was COR amended to conform with ACC/AHA 2015 Recommendation Classification System?. ### Response: LOE.


Instruction: What is the 2015 ACC/AHA Recommendation Classification System?

Output: IIa C-LDRecommendation reworded for clarity from 2014 Brain Swelling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2015 ACC/AHA Recommendation Classification System?. ### Response: IIa C-LDRecommendation reworded for clarity from 2014 Brain Swelling.


Instruction: What are hypothermia and barbiturates used for in the management of AIS?

Output: The data on the use of hypothermia and barbiturates for the management of AIS continue to be limited

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are hypothermia and barbiturates used for in the management of AIS?. ### Response: The data on the use of hypothermia and barbiturates for the management of AIS continue to be limited.


Instruction: What has been shown to have no impact on stroke outcomes?

Output: Hypothermia use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to have no impact on stroke outcomes?. ### Response: Hypothermia use.


Instruction: How many RCTs were analyzed?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs were analyzed?. ### Response: 6.


Instruction: What is needed to clarify the safety and efficacy of this intervention?

Output: Further trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to clarify the safety and efficacy of this intervention?. ### Response: Further trials.


Instruction: Data Supplement 1.4.12. Rehabilitation (Continued) COR LOE New, Revised, or UnchangedDownloaded from http://ahajournals.org by on what date?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data Supplement 1.4.12. Rehabilitation (Continued) COR LOE New, Revised, or UnchangedDownloaded from http://ahajournals.org by on what date?. ### Response: April 28, 2023.


Instruction: What may be reasonable to perform concurrently with pulmonary valve replacement?

Output: PA stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable to perform concurrently with pulmonary valve replacement?. ### Response: PA stenosis.


Instruction: What can correction of the hemodynamic lesion be clinically beneficial?

Output: PR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can correction of the hemodynamic lesion be clinically beneficial?. ### Response: PR.


Instruction: What has not consistently been demonstrated to reduce risk of subsequent VT or SCD?

Output: pulmonary valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not consistently been demonstrated to reduce risk of subsequent VT or SCD?. ### Response: pulmonary valve replacement.


Instruction: What may be considered in addition to pulmonary valve replacement?

Output: VT surgery and/or ICD implan-tation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered in addition to pulmonary valve replacement?. ### Response: VT surgery and/or ICD implan-tation.


Instruction: Where are references to studies that support recommendations summarized?

Output: Online Data Supplement 44

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are references to studies that support recommendations summarized?. ### Response: Online Data Supplement 44.


Instruction: What is indicated before right ventricle-to-PA conduit stenting or transcatheter valve placement?

Output: Coronary artery compression testing with simultaneous coronary angiography and high-pressure balloon dilation in the conduit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated before right ventricle-to-PA conduit stenting or transcatheter valve placement?. ### Response: Coronary artery compression testing with simultaneous coronary angiography and high-pressure balloon dilation in the conduit.


Instruction: What should be performed in patients with stented right ventricle-to-PA conduits and worsening PS or PR?

Output: evaluation for conduit complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed in patients with stented right ventricle-to-PA conduits and worsening PS or PR?. ### Response: evaluation for conduit complications.


Instruction: Fluoroscopy to evaluate for stent fracture and blood cultures to assess for what?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fluoroscopy to evaluate for stent fracture and blood cultures to assess for what?. ### Response: IE.


Instruction: What is reasonable to assess the hemodynamics?

Output: congestive HF, unexplained ventricular dysfunction or cyanosis cardiac catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to assess the hemodynamics?. ### Response: congestive HF, unexplained ventricular dysfunction or cyanosis cardiac catheterization.


Instruction: How is right ventricle-to-PA conduit intervention reasonable?

Output: adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is right ventricle-to-PA conduit intervention reasonable?. ### Response: adults.


Instruction: What is stenosis with reduced functional capacity?

Output: arrhythmia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stenosis with reduced functional capacity?. ### Response: arrhythmia.


Instruction: What is right ventricle-to-PA conduit widely used in the treatment of?

Output: severe RVOT obstructive lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is right ventricle-to-PA conduit widely used in the treatment of?. ### Response: severe RVOT obstructive lesions.


Instruction: How are conduits used in the treatment of severe RVOT obstructive lesions?

Output: Right ventricle–to-PA conduits are widely

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are conduits used in the treatment of severe RVOT obstructive lesions?. ### Response: Right ventricle–to-PA conduits are widely.


Instruction: What year was Circulation. 2018;138:e272–e391?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Circulation. 2018;138:e272–e391?. ### Response: 2018.


Instruction: What is the 2017 VA/SCD Guideline?

Output: Al-Khatib

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 VA/SCD Guideline?. ### Response: Al-Khatib.


Instruction: Who is the Director of the UCLA Cardiomyopathy Center?

Output: Gregg C. FonarowAhmanson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of the UCLA Cardiomyopathy Center?. ### Response: Gregg C. FonarowAhmanson.


Instruction: Who is the Associate Professor of Medicine at the University of Colorado School of Medicine?

Output: Daniel D. Matlock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Associate Professor of Medicine at the University of Colorado School of Medicine?. ### Response: Daniel D. Matlock.


Instruction: Where is Robert J. Myerburg a professor of medicine and physiology?

Output: University of Miami Miller School of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Robert J. Myerburg a professor of medicine and physiology?. ### Response: University of Miami Miller School of Medicine.


Instruction: What is the name of the professor of medicine at Miami Miller School of Medicine?

Output: Robert J. Myerburg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at Miami Miller School of Medicine?. ### Response: Robert J. Myerburg.


Instruction: Who is the Chair of the Department of Medicine at the University of Wisconsin Hospital and Clinics?

Output: Richard L. Page

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of the Department of Medicine at the University of Wisconsin Hospital and Clinics?. ### Response: Richard L. Page.


Instruction: What was reviewed and updated in conjunction with all meetings and/or conference calls of the writing committee during the document development process?

Output: relationships of committee members with industry and other entities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reviewed and updated in conjunction with all meetings and/or conference calls of the writing committee during the document development process?. ### Response: relationships of committee members with industry and other entities.


Instruction: The table does not necessarily reflect relationships with what?

Output: industry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The table does not necessarily reflect relationships with what?. ### Response: industry.


Instruction: What percentage of the voting stock or share of the business entity is a person deemed to have a significant interest in?

Output: ≥5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the voting stock or share of the business entity is a person deemed to have a significant interest in?. ### Response: ≥5%.


Instruction: How much of the fair market value of a business does the interest represent?

Output: ≥$5,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the fair market value of a business does the interest represent?. ### Response: ≥$5,000.


Instruction: How much of the fair market value of a business entity does the owner of the business have?

Output: ≥5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the fair market value of a business entity does the owner of the business have?. ### Response: ≥5%.


Instruction: What percentage of the person's gross income does the business entity receive from the person?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the person's gross income does the business entity receive from the person?. ### Response: 5%.


Instruction: Relationships that exist with no financial benefit are included for the purpose of what?

Output: transparency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Relationships that exist with no financial benefit are included for the purpose of what?. ### Response: transparency.


Instruction: What are also included for the purpose of transparency?

Output: Relationships that exist with no financial benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are also included for the purpose of transparency?. ### Response: Relationships that exist with no financial benefit.


Instruction: Relationships in this table are modest unless otherwise noted?

Output: Relationships that exist with no financial benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Relationships in this table are modest unless otherwise noted?. ### Response: Relationships that exist with no financial benefit.


Instruction: According to the ACC/AHA, a person has a relevant relationship if: a) the relationship or interest relates to what?

Output: the same or similar subject matter, intellectual property or asset, topic, or issue addressed in the document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: According to the ACC/AHA, a person has a relevant relationship if: a) the relationship or interest relates to what?. ### Response: the same or similar subject matter, intellectual property or asset, topic, or issue addressed in the document.


Instruction: Who makes a drug, drug class, or device addressed in the document?

Output: the company/entity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who makes a drug, drug class, or device addressed in the document?. ### Response: the company/entity.


Instruction: What is the name of the person or entity with whom the relationship exists?

Output: the company

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person or entity with whom the relationship exists?. ### Response: the company.


Instruction: What are writing committee members required to recuse themselves from voting on sections of a document?

Output: their specific relationships with industry and other entities may apply

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are writing committee members required to recuse themselves from voting on sections of a document?. ### Response: their specific relationships with industry and other entities may apply.


Instruction: What does the person have a reasonable potential for?

Output: financial, professional or other personal gain or loss

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the person have a reasonable potential for?. ### Response: financial, professional or other personal gain or loss.


Instruction: Who is required to recuse themselves from voting on sections to which their specific relationships with industry and other entities may apply?

Output: Writing committee members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is required to recuse themselves from voting on sections to which their specific relationships with industry and other entities may apply?. ### Response: Writing committee members.


Instruction: What does ACC indicate?

Output: American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACC indicate?. ### Response: American College of Cardiology.


Instruction: AHA, American Heart Association; EP, Electrophysiology; HRS, Heart Rhythm Society; IMPROVE-HF, Improve the Use of Evidence-Based Heart Failure Therapies in what area?

Output: Outpatient Setting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AHA, American Heart Association; EP, Electrophysiology; HRS, Heart Rhythm Society; IMPROVE-HF, Improve the Use of Evidence-Based Heart Failure Therapies in what area?. ### Response: Outpatient Setting.


Instruction: What is the acronym for Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting?

Output: IMPROVE-HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting?. ### Response: IMPROVE-HF.


Instruction: Who is the principal investigator of IMPROVE-HF?

Output: PI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the principal investigator of IMPROVE-HF?. ### Response: PI.


Instruction: What is the name of the book that treats heart failure chronic heart failure?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that treats heart failure chronic heart failure?. ### Response: NICE 2018.


Instruction: What are the results of the low sodium diet versus moderate sodium diet?

Output: Outcomes  No of Participants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the low sodium diet versus moderate sodium diet?. ### Response: Outcomes  No of Participants.


Instruction: What is GRADE?

Output: Quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GRADE?. ### Response: Quality of the evidence.


Instruction: How long is the time frame for the anticipated absolute effects?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the time frame for the anticipated absolute effects?. ### Response: 6 months.


Instruction: What is recommended for a moderate sodium diet?

Output: Advice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for a moderate sodium diet?. ### Response: Advice.


Instruction: What is the risk difference with Advice for low sodium diet (95% CI) Quality of Life Kansas City Cardiomyopathy Questionnaire Scale from: 0 to 100.

Output: High is worse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk difference with Advice for low sodium diet (95% CI) Quality of Life Kansas City Cardiomyopathy Questionnaire Scale from: 0 to 100.. ### Response: High is worse.


Instruction: What is better?

Output: High

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is better?. ### Response: High.


Instruction: Why is LOWa,b due to risk of bias?

Output: The me dian  quality of life in the control groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is LOWa,b due to risk of bias?. ### Response: The me dian  quality of life in the control groups.


Instruction: What was the median quality of life in the control groups?

Output: 70.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median quality of life in the control groups?. ### Response: 70.5.


Instruction: What was IQR in the intervention group?

Output: 4 lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was IQR in the intervention group?. ### Response: 4 lower.


Instruction: How much lower was umol/L?

Output: 7.8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much lower was umol/L?. ### Response: 7.8.


Instruction: Why was LOWa,b?

Output: risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was LOWa,b?. ### Response: risk of bias.


Instruction: What is the me dian renal function in the control groups?

Output: 106.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the me dian renal function in the control groups?. ### Response: 106.5.


Instruction: What is Creatinine (umol/L) 38 (1 study) 6 months  LOWa,b due to risk of bias?

Output: Renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Creatinine (umol/L) 38 (1 study) 6 months  LOWa,b due to risk of bias?. ### Response: Renal function.


Instruction: How many lower was the me dian renal function in the intervention groups?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many lower was the me dian renal function in the intervention groups?. ### Response: 4.


Instruction: How many increments were downgraded if the majority of the evidence was at high risk of bias?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were downgraded if the majority of the evidence was at high risk of bias?. ### Response: 2.


Instruction: If the evidence was at very high risk of bias, what could be assessed?

Output: LOWa,b,c due to risk of bias, indirectness, imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the evidence was at very high risk of bias, what could be assessed?. ### Response: LOWa,b,c due to risk of bias, indirectness, imprecision.


Instruction: Imprecision cannot be assessed due to reporting of what?

Output: median and inter -quartile range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Imprecision cannot be assessed due to reporting of what?. ### Response: median and inter -quartile range.


Instruction: What can be assessed because of reporting of median and inter-quartile range?

Output: Imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be assessed because of reporting of median and inter-quartile range?. ### Response: Imprecision.


Instruction: What does GRADE stand for?

Output: Quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GRADE stand for?. ### Response: Quality of the evidence.


Instruction: How long is the time frame for fluid restriction for heart failure?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the time frame for fluid restriction for heart failure?. ### Response: 6 months.


Instruction: What is the risk with advice on fluid restriction?

Output: Risk difference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk with advice on fluid restriction?. ### Response: Risk difference.


Instruction: What percentage of the population is at risk with advice on fluid restriction?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the population is at risk with advice on fluid restriction?. ### Response: 6 months.


Instruction: What is the visual analogue scale of Quality of Life?

Output: EQ5D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the visual analogue scale of Quality of Life?. ### Response: EQ5D.


Instruction: How many studies were carried out in 6 months?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were carried out in 6 months?. ### Response: 1.


Instruction: Why was the risk of fluid restriction so low?

Output: risk of bias, indirectness, imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the risk of fluid restriction so low?. ### Response: risk of bias, indirectness, imprecision.


Instruction: Why was the mean quality of life at 6 months in the control groups 70.5?

Output: risk of bias, indirectness, imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the mean quality of life at 6 months in the control groups 70.5?. ### Response: risk of bias, indirectness, imprecision.


Instruction: What was the average quality of living at 6 month in the intervention groups 8.68 lower?

Output: 24.96 lower to 7.6 higher)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the average quality of living at 6 month in the intervention groups 8.68 lower?. ### Response: 24.96 lower to 7.6 higher).


Instruction: How much lower was the Oedema Congestion score in the intervention groups?

Output: 8.68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much lower was the Oedema Congestion score in the intervention groups?. ### Response: 8.68.


Instruction: What is the scale from: 0 to 5?

Output: High is worse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the scale from: 0 to 5?. ### Response: High is worse.


Instruction: How many studies were conducted?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were conducted?. ### Response: 1.


Instruction: Why was the mean  VERY LOWa,c,d?

Output: risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the mean  VERY LOWa,c,d?. ### Response: risk of bias.


Instruction: What was the mean congestion sore in the control groups?

Output: 1.18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean congestion sore in the control groups?. ### Response: 1.18.


Instruction: What did the intervention groups have a mean congestion score of 0.07?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the intervention groups have a mean congestion score of 0.07?. ### Response: higher.


Instruction: What is angina unstable?

Output: Myocardial infarction Myocardial infarctions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is angina unstable?. ### Response: Myocardial infarction Myocardial infarctions.


Instruction: What is a heart arrest?

Output: myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a heart arrest?. ### Response: myocardial infarction.


Instruction: Where can you find the latest version of MeSH?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the latest version of MeSH?. ### Response: http://ahajournals.org.


Instruction: What are the Subject Headings (MeSH) Terms Key Words(Continued)Downloaded from http://ahajournals.org by on May 1, 2023?

Output: Appendix 1. ContinuedMedical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Subject Headings (MeSH) Terms Key Words(Continued)Downloaded from http://ahajournals.org by on May 1, 2023?. ### Response: Appendix 1. ContinuedMedical.


Instruction: What is the name of the STEEPLE trial?

Output: SafeTy and efficacy of enoxaparin in percutaneous coronary intervention patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the STEEPLE trial?. ### Response: SafeTy and efficacy of enoxaparin in percutaneous coronary intervention patients.


Instruction: How long did it take to determine the safety and efficacy of enoxaparin in percutaneous coronary intervention patients?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to determine the safety and efficacy of enoxaparin in percutaneous coronary intervention patients?. ### Response: 1-year.


Instruction: What year did JACC Cardiovasc Interv. 2009:2:1083-91?

Output: 2009;2:1083–91. 406. Choussat R, Montalescot G, Collet JP, et al. A unique, low dose of intra-venous enoxaparin in elective percutaneous coronary intervention. J Am Coll Cardiol. 2002;40:1943–50. 407. Smith SC Jr., Feldman TE, Hirshfeld JW Jr., et al. ACC/AHA/SCAI 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did JACC Cardiovasc Interv. 2009:2:1083-91?. ### Response: 2009;2:1083–91. 406. Choussat R, Montalescot G, Collet JP, et al. A unique, low dose of intra-venous enoxaparin in elective percutaneous coronary intervention. J Am Coll Cardiol. 2002;40:1943–50. 407. Smith SC Jr., Feldman TE, Hirshfeld JW Jr., et al. ACC/AHA/SCAI 2005.


Instruction: What is a unique, low dose of intra-venous enoxaparin in elective percutaneous coronary intervention?

Output: 406

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a unique, low dose of intra-venous enoxaparin in elective percutaneous coronary intervention?. ### Response: 406.


Instruction: When did J Am Coll Cardiol. 2002;40:1943-50?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2002;40:1943-50?. ### Response: 2002.


Instruction: What is the ACC/AHA/SCAI 2005 guideline update for?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA/SCAI 2005 guideline update for?. ### Response: percutaneous coronary intervention.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines update in 2005?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines update in 2005?. ### Response: percutaneous coronary intervention.


Instruction: What was the name of the group that updated the 2001 guidelines for percutaneous coronary intervention?

Output: American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the group that updated the 2001 guidelines for percutaneous coronary intervention?. ### Response: American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: When were the updated guidelines released?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were the updated guidelines released?. ### Response: 2005.


Instruction: What is reflected by a reduction in C-reactive protein?

Output: fects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reflected by a reduction in C-reactive protein?. ### Response: fects.


Instruction: The apparent cardioprotective effects of modestalcohol consumption reported in observational studies could represent what?

Output: uncontrolled confounding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The apparent cardioprotective effects of modestalcohol consumption reported in observational studies could represent what?. ### Response: uncontrolled confounding.


Instruction: What are more prevalent in nondrinkers than in light to moderate drinkers?

Output: coronary riskfactors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are more prevalent in nondrinkers than in light to moderate drinkers?. ### Response: coronary riskfactors.


Instruction: Inpatients with SIHD showed improved clinical out-comes with what type of alcohol consumption?

Output: wine or 1 ounce of spirits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inpatients with SIHD showed improved clinical out-comes with what type of alcohol consumption?. ### Response: wine or 1 ounce of spirits.


Instruction: Why should patients who do not drink alcohol not be encouraged to start?

Output: Because of the many healthand societal consequences of alcohol abuse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why should patients who do not drink alcohol not be encouraged to start?. ### Response: Because of the many healthand societal consequences of alcohol abuse.


Instruction: How many ounces of wine or 1 ounce of spirits are recommended per day for women?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ounces of wine or 1 ounce of spirits are recommended per day for women?. ### Response: 4.


Instruction: How many drinks per day are recommended for men?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drinks per day are recommended for men?. ### Response: 2.


Instruction: What should be avoided for patients with SIHD?

Output: exposure to increased airpollution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be avoided for patients with SIHD?. ### Response: exposure to increased airpollution.


Instruction: Is it reasonable for patients with SIHD to avoid exposure to increased air pollution?

Output: It is reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is it reasonable for patients with SIHD to avoid exposure to increased air pollution?. ### Response: It is reasonable.


Instruction: What can increase the risk of cardiovas-cular events?

Output: environmental influences such asexposure to air pollution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can increase the risk of cardiovas-cular events?. ### Response: environmental influences such asexposure to air pollution.


Instruction: What can increase the risk of cardiovascular events?

Output: air pollution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can increase the risk of cardiovascular events?. ### Response: air pollution.


Instruction: What is oxidative stress and inflammation responsible for?

Output: progression of atheroscle-rosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is oxidative stress and inflammation responsible for?. ### Response: progression of atheroscle-rosis.


Instruction: Fine particulate matter is associated with a heightenedrisk of death due to what?

Output: cardiovascular causes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fine particulate matter is associated with a heightenedrisk of death due to what?. ### Response: cardiovascular causes.


Instruction: What is the relative odds of AMI death in nonsmokers for each 10 mcg increase in PM2?

Output: 22%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relative odds of AMI death in nonsmokers for each 10 mcg increase in PM2?. ### Response: 22%.


Instruction: What is short-term exposure to higher concen-trations of pollution associated with?

Output: the risk for ACS and death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is short-term exposure to higher concen-trations of pollution associated with?. ### Response: the risk for ACS and death.


Instruction: What are patients with SIHD advised to avoid by staying indoors during transient elevations of air pollution?

Output: exposure to increased airpollution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with SIHD advised to avoid by staying indoors during transient elevations of air pollution?. ### Response: exposure to increased airpollution.


Instruction: Public policy efforts to minimize smallparticulate matter have the potential to reduce cardiac complications among patients with what?

Output: SIHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Public policy efforts to minimize smallparticulate matter have the potential to reduce cardiac complications among patients with what?. ### Response: SIHD.


Instruction: What is a potential to reduce cardiac complications among patients with SIHD?

Output: Public policy efforts to minimize smallparticulate matter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential to reduce cardiac complications among patients with SIHD?. ### Response: Public policy efforts to minimize smallparticulate matter.


Instruction: What should becontinued indefinitely in the absence of contraindi-cations in patientswith SIHD.

Output: Treatment with aspirin 75 to 162 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should becontinued indefinitely in the absence of contraindi-cations in patientswith SIHD.. ### Response: Treatment with aspirin 75 to 162 mg daily.


Instruction: What is reasonable when aspirin 75 to 162 mg daily?

Output: Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable when aspirin 75 to 162 mg daily?. ### Response: Treatment.


Instruction: What is reasonable when as-pirin is contraindicated in patients with SIHD?

Output: Treatment with clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable when as-pirin is contraindicated in patients with SIHD?. ### Response: Treatment with clopidogrel.


Instruction: What is not a benefit of dipyridamole?

Output: antiplatelettherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not a benefit of dipyridamole?. ### Response: antiplatelettherapy.


Instruction: What is not recommended as antiplatelettherapy for patients with SIHD?

Output: Dipyridamole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended as antiplatelettherapy for patients with SIHD?. ### Response: Dipyridamole.


Instruction: What is a key element of the thrombotic response to plaque disrup-tion?

Output: platelet aggregation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key element of the thrombotic response to plaque disrup-tion?. ### Response: platelet aggregation.


Instruction: What is the prognostic effect of cigarette smoking on stroke severity, disability, length of stay in hospital, and mortality in a cohort with cere-brovascular disease?

Output: long-term mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic effect of cigarette smoking on stroke severity, disability, length of stay in hospital, and mortality in a cohort with cere-brovascular disease?. ### Response: long-term mortality.


Instruction: What does Edjoc RK, Reid RD, Sharma M, Fang J do?

Output: Registry of the Canadian Stroke Network

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Edjoc RK, Reid RD, Sharma M, Fang J do?. ### Response: Registry of the Canadian Stroke Network.


Instruction: What predicts long-term mortality in stroke?

Output: Smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts long-term mortality in stroke?. ### Response: Smoking.


Instruction: What is the name of the study that examined cardiovascular risk factors and 5-year mor-tality?

Output: Copenhagen Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined cardiovascular risk factors and 5-year mor-tality?. ### Response: Copenhagen Stroke Study.


Instruction: What is the name of the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study?

Output: Smoking predicts long-term mortality in stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study?. ### Response: Smoking predicts long-term mortality in stroke.


Instruction: What is a high risk of recurrence in patients with transient ischemic attack or minor stroke?

Output: Factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a high risk of recurrence in patients with transient ischemic attack or minor stroke?. ### Response: Factors.


Instruction: What is the doi: 10.1161/STROKEAHA.107.505438 162?

Output: Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1161/STROKEAHA.107.505438 162?. ### Response: Stroke.


Instruction: What is the name of the study?

Output: European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.


Instruction: When was this study published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 28, 2023.


Instruction: What is ahajournals.org about?

Output: Alcohol intake

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ahajournals.org about?. ### Response: Alcohol intake.


Instruction: What does cefepime do against ceftazidime-resistant Gram-negative bacilli using low and high inocula?

Output: Activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does cefepime do against ceftazidime-resistant Gram-negative bacilli using low and high inocula?. ### Response: Activity.


Instruction: What does Bayer AS, Hirano L, Yih J. develop during therapy of Pseudomonas aeruginosa experimentally?

Output: beta-lactam resis-tance and increased quinolone MICs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Bayer AS, Hirano L, Yih J. develop during therapy of Pseudomonas aeruginosa experimentally?. ### Response: beta-lactam resis-tance and increased quinolone MICs.


Instruction: What is the cause of endocarditis in experimental Pseudomonas aeruginosa?

Output: aminoglycoside-resistant Streptococcus faecalis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of endocarditis in experimental Pseudomonas aeruginosa?. ### Response: aminoglycoside-resistant Streptococcus faecalis.


Instruction: What was the name of the antimicrob agent that chemother in 1988?

Output: Antimicrob Agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the antimicrob agent that chemother in 1988?. ### Response: Antimicrob Agents.


Instruction: How was beta-lactamase produced?

Output: due to aminoglycoside-resistant Streptococcus faecalis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was beta-lactamase produced?. ### Response: due to aminoglycoside-resistant Streptococcus faecalis.


Instruction: What is the name of the bacterial endocar -ditis?

Output: Staphylococcus aureus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the bacterial endocar -ditis?. ### Response: Staphylococcus aureus.


Instruction: What is one of the reasons for failure of therapy in pseudomonas endocarditis: selection of resistant mutants?

Output: In vitro resistance to thrombin-induced platelet microbici-dal protein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the reasons for failure of therapy in pseudomonas endocarditis: selection of resistant mutants?. ### Response: In vitro resistance to thrombin-induced platelet microbici-dal protein.


Instruction: When did J Am Med Assoc. 1950;144:524-527?

Output: 1950

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Med Assoc. 1950;144:524-527?. ### Response: 1950.


Instruction: How long did it take to treat streptococcal endocar -ditis?

Output: two-week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to treat streptococcal endocar -ditis?. ### Response: two-week.


Instruction: What is the name of the prospective multicenter study that evaluated 14 days of ceftriaxone and netilmicin?

Output: Francioli

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective multicenter study that evaluated 14 days of ceftriaxone and netilmicin?. ### Response: Francioli.


Instruction: How long was it taken to treat right-sided Staphylococcus aureus?

Output: two-week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was it taken to treat right-sided Staphylococcus aureus?. ### Response: two-week.


Instruction: What is the treatment for right-sided Staphylococcus aureus endocarditis in intravenous drug abusers?

Output: two-week combination therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the treatment for right-sided Staphylococcus aureus endocarditis in intravenous drug abusers?. ### Response: two-week combination therapy.


Instruction: How long did combination therapy with gentamicin last?

Output: 14 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did combination therapy with gentamicin last?. ### Response: 14 days.


Instruction: What was the effect of cloxacil-lin with and without gentamicine in short-term therapy?

Output: Effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of cloxacil-lin with and without gentamicine in short-term therapy?. ### Response: Effectiveness.


Instruction: What is cloxacil-lin with and without gentamicin used for?

Output: short-term therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cloxacil-lin with and without gentamicin used for?. ### Response: short-term therapy.


Instruction: What is the name of the randomized, controlled trial?

Output: Effectiveness of cloxacil-lin with and without gentamicin in short-term therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, controlled trial?. ### Response: Effectiveness of cloxacil-lin with and without gentamicin in short-term therapy.


Instruction: How long did it take to treat Staphylococcus aureus endocarditis?

Output: two-week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to treat Staphylococcus aureus endocarditis?. ### Response: two-week.


Instruction: What does resistance to thrombin-induced platelet microbici-dal protein correlate with?

Output: an endovascular infectious source

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does resistance to thrombin-induced platelet microbici-dal protein correlate with?. ### Response: an endovascular infectious source.


Instruction: What correlates with an endovascular infectious source?

Output: In vitro resistance to thrombin-induced platelet microbici-dal protein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What correlates with an endovascular infectious source?. ### Response: In vitro resistance to thrombin-induced platelet microbici-dal protein.


Instruction: Antimicrob Agents Chemother. 1998;42:3169–3172.

Output: 94

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antimicrob Agents Chemother. 1998;42:3169–3172.. ### Response: 94.


Instruction: What aspects of therapy of experimental endocarditis?

Output: namic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What aspects of therapy of experimental endocarditis?. ### Response: namic.


Instruction: Infect Dis Clin North Am. 1993;7:37–51.

Output: endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infect Dis Clin North Am. 1993;7:37–51.. ### Response: endocarditis.


Instruction: What is the name of the technique used to evaluate the diffusion of antibiotics into cardiac vegetations?

Output: quantitative autoradiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the technique used to evaluate the diffusion of antibiotics into cardiac vegetations?. ### Response: quantitative autoradiography.


Instruction: What was the title of the method used to assess the diffusion into cardiac plants?

Output: autoradiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the method used to assess the diffusion into cardiac plants?. ### Response: autoradiography.


Instruction: How many antibiotics did Maziere B and Ottaviani M have?

Output: 95

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many antibiotics did Maziere B and Ottaviani M have?. ### Response: 95.


Instruction: What is Ceftriaxone diffusion into cardiac fibrin vegetation?

Output: quali-tative and quantitative evaluation by autoradiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Ceftriaxone diffusion into cardiac fibrin vegetation?. ### Response: quali-tative and quantitative evaluation by autoradiography.


Instruction: What is Fundam Clin Pharmacol. 1991;5:53-60?

Output: Ceftriaxone diffusion into cardiac fibrin vegetation: quali-tative and quantitative evaluation by autoradiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Fundam Clin Pharmacol. 1991;5:53-60?. ### Response: Ceftriaxone diffusion into cardiac fibrin vegetation: quali-tative and quantitative evaluation by autoradiography.


Instruction: What is the effect of temafloxacin in experimental Streptococcus adjacens endocarditis and autoradio-graphic diffusion pattern?

Output: Efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of temafloxacin in experimental Streptococcus adjacens endocarditis and autoradio-graphic diffusion pattern?. ### Response: Efficacy.


Instruction: Antimicrob Agents Chemother. 1992;36:2216–2221.

Output: Efficacy of temafloxacin in experimental Streptococcus adjacens endocarditis and autoradio-graphic diffusion pattern of [14C]temafloxacin in cardiac vegetations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antimicrob Agents Chemother. 1992;36:2216–2221.. ### Response: Efficacy of temafloxacin in experimental Streptococcus adjacens endocarditis and autoradio-graphic diffusion pattern of [14C]temafloxacin in cardiac vegetations.


Instruction: What is NICE 2018?

Output: All rights reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: All rights reserved.


Instruction: What is the study design and sample size?

Output: Finding  Quality assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the study design and sample size?. ### Response: Finding  Quality assessment.


Instruction: How many studies contribute to the finding?

Output: Number

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies contribute to the finding?. ### Response: Number.


Instruction: How many studies contributed to the finding Design Criteria Rating Overall assessment of confidence Improving communication/ information flow 4b Ongoing relationship 226, 133, 313 Individual interviews with pt + carers and focus groups with HCPs

Output: Number

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies contributed to the finding Design Criteria Rating Overall assessment of confidence Improving communication/ information flow 4b Ongoing relationship 226, 133, 313 Individual interviews with pt + carers and focus groups with HCPs. ### Response: Number.


Instruction: HCPs Ethnographic study involving pt and what else?

Output: HCPs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HCPs Ethnographic study involving pt and what else?. ### Response: HCPs.


Instruction: What was suggested for information and education to be delivered within an ongoing relationship with the patient?

Output: Ethnographic study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was suggested for information and education to be delivered within an ongoing relationship with the patient?. ### Response: Ethnographic study.


Instruction: What are some concerns about coherence?

Output: No or very minor concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some concerns about coherence?. ### Response: No or very minor concerns.


Instruction: What is another concern about relevance?

Output: Adequacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another concern about relevance?. ### Response: Adequacy.


Instruction: How is communication/information flow improved?

Output: Tailoring of information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is communication/information flow improved?. ### Response: Tailoring of information.


Instruction: What type of interviews are conducted with pt + carers and focus groups with HCPs?

Output: Individual

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of interviews are conducted with pt + carers and focus groups with HCPs?. ### Response: Individual.


Instruction: What types of interviews do HCP's do?

Output: Individual interviews with pt + carers and focus groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What types of interviews do HCP's do?. ### Response: Individual interviews with pt + carers and focus groups.


Instruction: What type of interviews with pt and following bereavement intervi ews with informal carers require staff to tailor the information to the needs of the individual?

Output: In-depth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of interviews with pt and following bereavement intervi ews with informal carers require staff to tailor the information to the needs of the individual?. ### Response: In-depth.


Instruction: What are concerns about methodological limitations HIGH?

Output: Coherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are concerns about methodological limitations HIGH?. ### Response: Coherence.


Instruction: What are some concerns about methodological limitations?

Output: Moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some concerns about methodological limitations?. ### Response: Moderate.


Instruction: What is a concern about coherence that is very minor or very minor?

Output: relevance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a concern about coherence that is very minor or very minor?. ### Response: relevance.


Instruction: What is dependent diabetes mellitus?

Output: nephropathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is dependent diabetes mellitus?. ### Response: nephropathy.


Instruction: What is the name of the study that investigated the renal and metabolic effects of 1-year treatment with ramipril or atenolol in NIDDM patients withmicroalbuminuria?

Output: Diabetologia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the renal and metabolic effects of 1-year treatment with ramipril or atenolol in NIDDM patients withmicroalbuminuria?. ### Response: Diabetologia.


Instruction: What type of diabetic patients have persistent albuminuria?

Output: non-insulin-dependent (type II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetic patients have persistent albuminuria?. ### Response: non-insulin-dependent (type II.


Instruction: What is another name for type II diabetics?

Output: non-insulin-dependent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for type II diabetics?. ### Response: non-insulin-dependent.


Instruction: When did Clin Sci (Lond) issue 82:19-23.250?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Clin Sci (Lond) issue 82:19-23.250?. ### Response: 1992.


Instruction: What does lisinopril and nifedipine have on albuminuria and tubular transport functions in diabetics with nephropathy?

Output: Contrasting effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lisinopril and nifedipine have on albuminuria and tubular transport functions in diabetics with nephropathy?. ### Response: Contrasting effects.


Instruction: When did J Intern Med issue 229:163-170.252?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Intern Med issue 229:163-170.252?. ### Response: 1991.


Instruction: How does Valsartan improve arterial stiffness in type 2 diabetes?

Output: independently of blood pressure lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Valsartan improve arterial stiffness in type 2 diabetes?. ### Response: independently of blood pressure lowering.


Instruction: What is the name of the drug used to treat type 2 diabetic nephropathy and hypertension?

Output: spirapril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat type 2 diabetic nephropathy and hypertension?. ### Response: spirapril.


Instruction: When did Blood Press publish a study on spirapril andisradipine in 1993?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Blood Press publish a study on spirapril andisradipine in 1993?. ### Response: 1993.


Instruction: What type of diabetic nephropathy and hypertension are treated with Blood Press in 1993?

Output: 2:301 –308.254

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetic nephropathy and hypertension are treated with Blood Press in 1993?. ### Response: 2:301 –308.254.


Instruction: What is the effect of an anangiotensin converting enzyme inhibitor and calcium antagonist in diabetic patients?

Output: comparative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of an anangiotensin converting enzyme inhibitor and calcium antagonist in diabetic patients?. ### Response: comparative.


Instruction: What is the name of the 1993 study that investigated the effects of nisoldipine and lisinopril on leftventricular mass and function in diabetic nephropathy?

Output: J Hum Hypertens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 1993 study that investigated the effects of nisoldipine and lisinopril on leftventricular mass and function in diabetic nephropathy?. ### Response: J Hum Hypertens.


Instruction: What was the name given to the study that examined the effect of the two drugs on ventricular mass?

Output: ADVANCE Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name given to the study that examined the effect of the two drugs on ventricular mass?. ### Response: ADVANCE Collaborative Group.


Instruction: When was Diabetes Care published?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Diabetes Care published?. ### Response: 1999.


Instruction: What does organicion clearance following chronic ACE inhibition do in patients with type 1 diabetes?

Output: Increased tubular organicion clearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does organicion clearance following chronic ACE inhibition do in patients with type 1 diabetes?. ### Response: Increased tubular organicion clearance.


Instruction: What is the name of the randomised controlled trial that evaluated the effects of perindopril and indapamide on macrovascular and microvascular outcomes?

Output: ADVANCE Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial that evaluated the effects of perindopril and indapamide on macrovascular and microvascular outcomes?. ### Response: ADVANCE Collaborative Group.


Instruction: What is the name of the randomised controlled trial?

Output: ADVANCE Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial?. ### Response: ADVANCE Collaborative Group.


Instruction: What is finerenone's effect on kidney disease outcomes in type 2 diabetes?

Output: improves arterialstiffness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is finerenone's effect on kidney disease outcomes in type 2 diabetes?. ### Response: improves arterialstiffness.


Instruction: What are angiotensin converting enzymeinhibitors used for?

Output: preventing theprogression of diabetic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are angiotensin converting enzymeinhibitors used for?. ### Response: preventing theprogression of diabetic kidney disease.


Instruction: What is the name of the cochrane database?

Output: Cochrane Database Syst Rev

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the cochrane database?. ### Response: Cochrane Database Syst Rev.


Instruction: How is GRADE defined?

Output: Rating the quality of evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is GRADE defined?. ### Response: Rating the quality of evidence.


Instruction: What year did J Clin Epidemiol have 64:401 –406.261?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Clin Epidemiol have 64:401 –406.261?. ### Response: 2011.


Instruction: What is the effect of angiotensin-converting enzymes?

Output: preventing theprogression of diabetic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of angiotensin-converting enzymes?. ### Response: preventing theprogression of diabetic kidney disease.


Instruction: What is the complete set of subgroup grading criteria?

Output: Figure 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the complete set of subgroup grading criteria?. ### Response: Figure 3.


Instruction: What was the study quality graded according to?

Output: Grading of Recommendations Assessment, Development and Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the study quality graded according to?. ### Response: Grading of Recommendations Assessment, Development and Evaluation.


Instruction: Step 2: Reduce grade Step 3: Raise grade for quality of evidenceand definitionRandomized trials = HighObservational study = LowStudy quality/C01 level if serious limitations/C02 levels if very serious limitationsWhat is important inconsistency?

Output: Consistency/C01 level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Step 2: Reduce grade Step 3: Raise grade for quality of evidenceand definitionRandomized trials = HighObservational study = LowStudy quality/C01 level if serious limitations/C02 levels if very serious limitationsWhat is important inconsistency?. ### Response: Consistency/C01 level.


Instruction: What is unlikely to change the confidence in the estimate of the effect?

Output: Further research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unlikely to change the confidence in the estimate of the effect?. ### Response: Further research.


Instruction: What is likely tohave a major threat to validity if evidence of adose- response gradient exists?

Output: low event rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely tohave a major threat to validity if evidence of adose- response gradient exists?. ### Response: low event rate.


Instruction: What is the estimate of the effect likely to have an important impact on?

Output: confidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the estimate of the effect likely to have an important impact on?. ### Response: confidence.


Instruction: What level if spare?

Output: Sparse if there is only one study or if total No500

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What level if spare?. ### Response: Sparse if there is only one study or if total No500.


Instruction: Further research is very likely tohave an importantimpact on what?

Output: confidence in the estimate of effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Further research is very likely tohave an importantimpact on what?. ### Response: confidence in the estimate of effect.


Instruction: What is the abbreviation for GRADE?

Output: Grading of Recommendations Assessment, Development and Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the abbreviation for GRADE?. ### Response: Grading of Recommendations Assessment, Development and Evaluation.


Instruction: What is a strong evidence of association defined as based on consistent evidence?

Output: significant relative risk of 42

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strong evidence of association defined as based on consistent evidence?. ### Response: significant relative risk of 42.


Instruction: What is defined as'significant relative risk of 45(o0.2)' based on direct evidence with no major threats to validity?

Output: Very strong evidence of association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is defined as'significant relative risk of 45(o0.2)' based on direct evidence with no major threats to validity?. ### Response: Very strong evidence of association.


Instruction: What if there is only one study or total study?

Output: Sparse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What if there is only one study or total study?. ### Response: Sparse.


Instruction: What does validity.cSparse do if there is only one study or if total No500?

Output: Imprecise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does validity.cSparse do if there is only one study or if total No500?. ### Response: Imprecise.


Instruction: What is imprecise if a low event rate is present in either arm or confidence interval spanning a range 41?

Output: Imprecise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is imprecise if a low event rate is present in either arm or confidence interval spanning a range 41?. ### Response: Imprecise.


Instruction: What is the name of the position statement from Kidney Disease: Improving Global Outcomes?

Output: KDIGO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the position statement from Kidney Disease: Improving Global Outcomes?. ### Response: KDIGO.


Instruction: What is Kidney International Supplements (2013) 3?

Output: methods for guideline development

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Kidney International Supplements (2013) 3?. ### Response: methods for guideline development.


Instruction: What can vagal maneuvers terminate SVT?

Output: vagal maneuvers can terminate SVT, so patient education on this maneuver may help to avoid a more prolonged  tachycardia episode and reduce the need to seek medical attention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can vagal maneuvers terminate SVT?. ### Response: vagal maneuvers can terminate SVT, so patient education on this maneuver may help to avoid a more prolonged  tachycardia episode and reduce the need to seek medical attention.


Instruction: What should be performed with the patient in the supine position?

Output: Vagal maneuvers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed with the patient in the supine position?. ### Response: Vagal maneuvers.


Instruction: How long can a patient be taught to perform a Valsalva maneuver?

Output: 10 to 30 seconds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long can a patient be taught to perform a Valsalva maneuver?. ### Response: 10 to 30 seconds.


Instruction: What is a vagal maneuver based on the classic diving reflex?

Output: applying an ice-cold, wet towel to the face

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a vagal maneuver based on the classic diving reflex?. ### Response: applying an ice-cold, wet towel to the face.


Instruction: What is an ice-cold, wet towel applied to the face?

Output: vagal maneuver based on the classic diving reflex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ice-cold, wet towel applied to the face?. ### Response: vagal maneuver based on the classic diving reflex.


Instruction: What is reasonable for ongoing management in patients without structural heart disease or ischemic heart disease who have symptomatic SVT and prefer not to undergo catheter ablation?

Output: Flecainide or propafenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for ongoing management in patients without structural heart disease or ischemic heart disease who have symptomatic SVT and prefer not to undergo catheter ablation?. ### Response: Flecainide or propafenone.


Instruction: What has been demonstrated the efficacy of daily therapy with propafenone?

Output: RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been demonstrated the efficacy of daily therapy with propafenone?. ### Response: RCTs.


Instruction: What is propafenone?

Output: 450 mg/day to 900 mg/day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is propafenone?. ### Response: 450 mg/day to 900 mg/day.


Instruction: What is flecainide?

Output: 100 mg/day to 300 mg/day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is flecainide?. ### Response: 100 mg/day to 300 mg/day.


Instruction: How many months of effective and safe treatment was found in 1 RCT?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many months of effective and safe treatment was found in 1 RCT?. ### Response: 12.


Instruction: What was the safest treatment for 2 attacks of arrhythmia?

Output: propafenone and 93% for flecainide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the safest treatment for 2 attacks of arrhythmia?. ### Response: propafenone and 93% for flecainide.


Instruction: What is the safe treatment for propafenone?

Output: 86%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the safe treatment for propafenone?. ### Response: 86%.


Instruction: How much safe treatment was for flecainide?

Output: 93%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much safe treatment was for flecainide?. ### Response: 93%.


Instruction: Which drugs have a risk of proarrhythma in patients with structural heart disease or ischemic heart disease?

Output: flecainide and propafenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drugs have a risk of proarrhythma in patients with structural heart disease or ischemic heart disease?. ### Response: flecainide and propafenone.


Instruction: What is recommended for acute treatment in patients with hemodynamically stable SVT?

Output: Synchronized cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for acute treatment in patients with hemodynamically stable SVT?. ### Response: Synchronized cardioversion.


Instruction: What are beta blockers, diltiazem or verapamil ineffective for?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are beta blockers, diltiazem or verapamil ineffective for?. ### Response: patients.


Instruction: What is highly effective in terminating SVT?

Output: Synchronized cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is highly effective in terminating SVT?. ### Response: Synchronized cardioversion.


Instruction: What is performed after adequate sedation or anesthesia?

Output: when the patient is stable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed after adequate sedation or anesthesia?. ### Response: when the patient is stable.


Instruction: Most stable patients with SVT respond to what?

Output: pharmacological therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most stable patients with SVT respond to what?. ### Response: pharmacological therapy.