Instruction: Where was he a visiting scholar for extended periods?

Output: Karolinska Institute in Swedenand the George Institute in Australia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was he a visiting scholar for extended periods?. ### Response: Karolinska Institute in Swedenand the George Institute in Australia.


Instruction: In what country was the Karolinska Institute located?

Output: Sweden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what country was the Karolinska Institute located?. ### Response: Sweden.


Instruction: What is Dr. Pecoits-Filhoserved a member of?

Output: Executive Committee of the ISN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Dr. Pecoits-Filhoserved a member of?. ### Response: Executive Committee of the ISN.


Instruction: What was he a part of from 2017 to 2019?

Output: Executive Committee of the ISN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was he a part of from 2017 to 2019?. ### Response: Executive Committee of the ISN.


Instruction: Who was a consultant from 2016 to 2018?

Output: Dr. Pecoits-Filhos

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was a consultant from 2016 to 2018?. ### Response: Dr. Pecoits-Filhos.


Instruction: Who is the chief of the Division of Nephrology at Tufts MedicalCenter?

Output: Mark J. Sarnak

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the chief of the Division of Nephrology at Tufts MedicalCenter?. ### Response: Mark J. Sarnak.


Instruction: What is Mark J. Sarnak's primary research interest?

Output: cardiovascular disease inCKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Mark J. Sarnak's primary research interest?. ### Response: cardiovascular disease inCKD.


Instruction: What is Dr. Sarnak's primary research interest?

Output: cardiovascular disease inCKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Dr. Sarnak's primary research interest?. ### Response: cardiovascular disease inCKD.


Instruction: What is the primary focus of Dr. Sarnak's research in CKD?

Output: cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary focus of Dr. Sarnak's research in CKD?. ### Response: cardiovascular disease.


Instruction: Who is the main funding source for his research?

Output: NIH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the main funding source for his research?. ### Response: NIH.


Instruction: What is the name of the systematic review of economic evaluations in kidney transplantation?

Output: Transplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of economic evaluations in kidney transplantation?. ### Response: Transplantation.


Instruction: How long does ambulatory blood pressure last in children?

Output: 24-h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does ambulatory blood pressure last in children?. ### Response: 24-h.


Instruction: When was J Hypertens 21:1995 –2007?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was J Hypertens 21:1995 –2007?. ### Response: 2002.


Instruction: What is the European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents?. ### Response: 2016.


Instruction: What are the values and role of bodydimensions?

Output: normalized reference values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the values and role of bodydimensions?. ### Response: normalized reference values.


Instruction: What is a role of antihypertensive drug management in childhood chronic renal parenchymal disease?

Output: Systemic hypertensionand proteinuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a role of antihypertensive drug management in childhood chronic renal parenchymal disease?. ### Response: Systemic hypertensionand proteinuria.


Instruction: What is the name of the randomized study that examined cardiac geometry andfunction in CKD children?

Output: Matteucci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized study that examined cardiac geometry andfunction in CKD children?. ### Response: Matteucci.


Instruction: What is the name of the randomized study conducted on children during strict BP control?

Output: Matteucci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized study conducted on children during strict BP control?. ### Response: Matteucci.


Instruction: What is a scientific statement from the American Heart Association?

Output: ambulatory bloodpressure monitoring in children and adolescents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scientific statement from the American Heart Association?. ### Response: ambulatory bloodpressure monitoring in children and adolescents.


Instruction: What is the difference between ambulatory and clinic blood pressure measurements in children with CKD?

Output: Twenty-four-hour

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between ambulatory and clinic blood pressure measurements in children with CKD?. ### Response: Twenty-four-hour.


Instruction: What is the difference between fice,ambulatory and home blood pressure in children and adolescents on the basis of normalcy tables?

Output: Comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between fice,ambulatory and home blood pressure in children and adolescents on the basis of normalcy tables?. ### Response: Comparison.


Instruction: When did the J Hum Hypertens. 2011:25:218–223.362?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Hum Hypertens. 2011:25:218–223.362?. ### Response: 2011.


Instruction: What was the name of the study that examined the accuracy of automated blood pressure measurements in children?

Output: Hypertension . 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that examined the accuracy of automated blood pressure measurements in children?. ### Response: Hypertension . 2017.


Instruction: What type of blood pressure monitoring is recommended in children with chronic renal failure?

Output: ambulatory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of blood pressure monitoring is recommended in children with chronic renal failure?. ### Response: ambulatory.


Instruction: What is the name of the journal that studies the prevalence of glomerular and nonglomerular kidney disease in children?

Output: Am J Kidney Dis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the prevalence of glomerular and nonglomerular kidney disease in children?. ### Response: Am J Kidney Dis.


Instruction: What is the Chronic Kidney Disease in Children cohort?

Output: CKiD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Chronic Kidney Disease in Children cohort?. ### Response: CKiD.


Instruction: What was the name of the systematic review of evidence on clinical utility?

Output: Home blood pressuremonitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic review of evidence on clinical utility?. ### Response: Home blood pressuremonitoring.


Instruction: What is the name of the systematic review of evidence on clinical utility?

Output: Home blood pressuremonitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of evidence on clinical utility?. ### Response: Home blood pressuremonitoring.


Instruction: What are the names of the authors?

Output: Stergiou GS, Karpettas N, Panagiotakos DB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors?. ### Response: Stergiou GS, Karpettas N, Panagiotakos DB.


Instruction: Who is the author of the abstract?

Output: Dionne JM, Jiang S, Ng D, et al. Ambulatory blood pressure and CKDprogression in the CKiD cohort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the abstract?. ### Response: Dionne JM, Jiang S, Ng D, et al. Ambulatory blood pressure and CKDprogression in the CKiD cohort.


Instruction: What is the name of the study that identified important outcomes for young people with CKD and their caregivers?

Output: a nominal group techniquestudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that identified important outcomes for young people with CKD and their caregivers?. ### Response: a nominal group techniquestudy.


Instruction: What is Halbach S. Practical application of ABPM in pediatric nephrologyclinic?

Output: Achieved clinic blood pressure level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Halbach S. Practical application of ABPM in pediatric nephrologyclinic?. ### Response: Achieved clinic blood pressure level.


Instruction: What was the blood pressure level in the clinic?

Output: Achieved clinic blood pressure level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the blood pressure level in the clinic?. ### Response: Achieved clinic blood pressure level.


Instruction: What is the glycemic index?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the glycemic index?. ### Response: blood pressure.


Instruction: How many people were able to achieve the clinic blood pressure?

Output: Flynn

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were able to achieve the clinic blood pressure?. ### Response: Flynn.


Instruction: What is the representative BP?

Output: diastolic BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the representative BP?. ### Response: diastolic BP.


Instruction: What does ABPM mean?

Output: ambulatory blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ABPM mean?. ### Response: ambulatory blood pressure monitoring.


Instruction: ACC stands for American College of Cardiology; AHA stands for what?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ACC stands for American College of Cardiology; AHA stands for what?. ### Response: American Heart Association.


Instruction: What is the acronym for electronic health record?

Output: EHR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for electronic health record?. ### Response: EHR.


Instruction: What is HBPM?

Output: home blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HBPM?. ### Response: home blood pressure monitoring.


Instruction: HEDIS stands for Healthcare Effectiveness Data and Information Set?

Output: HEDIS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HEDIS stands for Healthcare Effectiveness Data and Information Set?. ### Response: HEDIS.


Instruction: What is the acronym for National Committee for Quality Assurance?

Output: NCQA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for National Committee for Quality Assurance?. ### Response: NCQA.


Instruction: What does NQF stand for?

Output: National Quality Forum

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NQF stand for?. ### Response: National Quality Forum.


Instruction: What is the acronym for systolic blood pressure?

Output: SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for systolic blood pressure?. ### Response: SBP.


Instruction: What does VBM stand for?

Output: Value-Based Payment Modifier

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does VBM stand for?. ### Response: Value-Based Payment Modifier.


Instruction: Where can you find the latest version of this article?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the latest version of this article?. ### Response: http://ahajournals.org.


Instruction: When was this article published?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: May 3, 2023.


Instruction: What is the focus of the Focused Update on Atrial FibrillationCirculation. 2019;140:e125–e151. DOI: 10.1161/CIR.0000000000000665 July 9, 2019 e147CLINICAL STATEMENTS AND GUIDELINES S7.4-19. Vamos M, Erath JW, Hohnloser SH. Digoxin-associated mortality: a systematic review and meta-analysis of the literature. 2015;36:1831–8.

Output: Digoxin-associated mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the Focused Update on Atrial FibrillationCirculation. 2019;140:e125–e151. DOI: 10.1161/CIR.0000000000000665 July 9, 2019 e147CLINICAL STATEMENTS AND GUIDELINES S7.4-19. Vamos M, Erath JW, Hohnloser SH. Digoxin-associated mortality: a systematic review and meta-analysis of the literature. 2015;36:1831–8.. ### Response: Digoxin-associated mortality.


Instruction: What is the prognostic significance of atrial fibrillation/-flutter following acute myocardial infarction?

Output: occurrence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic significance of atrial fibrillation/-flutter following acute myocardial infarction?. ### Response: occurrence.


Instruction: What study group conducted the TRAndolapril Cardiac Evaluation?

Output: TRACE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study group conducted the TRAndolapril Cardiac Evaluation?. ### Response: TRACE.


Instruction: When was the Eur Heart J 20:748–54?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur Heart J 20:748–54?. ### Response: 1999.


Instruction: What is the name of the CAPRICORN trial?

Output: Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the CAPRICORN trial?. ### Response: Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction.


Instruction: How many prognostic scores were evaluated for prediction of stroke, thromboembolic and coronary events, all-cause events?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prognostic scores were evaluated for prediction of stroke, thromboembolic and coronary events, all-cause events?. ### Response: 5.


Instruction: Fauchier L, Lecoq C, Ancedy Y, et al. What is carvedilol used for?

Output: Evaluation of 5 prognostic scores

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fauchier L, Lecoq C, Ancedy Y, et al. What is carvedilol used for?. ### Response: Evaluation of 5 prognostic scores.


Instruction: What are scores for prediction of stroke, thromboembolic and coronary events, all-cause mortality, and major adverse cardiac events in patients with atrial fibrillation and stenting?

Output: 5 prognostic scores

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are scores for prediction of stroke, thromboembolic and coronary events, all-cause mortality, and major adverse cardiac events in patients with atrial fibrillation and stenting?. ### Response: 5 prognostic scores.


Instruction: What is a 6-month GRACE risk score a useful tool to predict?

Output: stroke after an acute coro-nary syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 6-month GRACE risk score a useful tool to predict?. ### Response: stroke after an acute coro-nary syndrome.


Instruction: What is a useful tool to predict stroke after an acute coro-nary syndrome?

Output: 6-month GRACE risk score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a useful tool to predict stroke after an acute coro-nary syndrome?. ### Response: 6-month GRACE risk score.


Instruction: What does apixaban do in patients with atrial fibrillation, not caused by a heart valve problem?

Output: at risk for thrombosis (blood clots) due to having had a recent coronary event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does apixaban do in patients with atrial fibrillation, not caused by a heart valve problem?. ### Response: at risk for thrombosis (blood clots) due to having had a recent coronary event.


Instruction: What is the term for blood clots?

Output: thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for blood clots?. ### Response: thrombosis.


Instruction: What is thrombosis due to having had a recent coronary event such as a heart attack or a procedure to open the vessels of the heart?

Output: blood clots

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is thrombosis due to having had a recent coronary event such as a heart attack or a procedure to open the vessels of the heart?. ### Response: blood clots.


Instruction: Where is the identifier for NCT02415400?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the identifier for NCT02415400?. ### Response: https://www.clinicaltrials.gov.


Instruction: What is ENTRUST-AF-PCI?

Output: Edoxaban treatment versus vitamin K antago-nist in patients with atrial fibrillation undergoing percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ENTRUST-AF-PCI?. ### Response: Edoxaban treatment versus vitamin K antago-nist in patients with atrial fibrillation undergoing percutaneous coronary intervention.


Instruction: What is the identifier of NCT02866175.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the identifier of NCT02866175.. ### Response: https://www.clinicaltrials.gov.


Instruction: What does the new section of Device Detection of AF and Atrial Flutter contain?

Output: S7.12-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the new section of Device Detection of AF and Atrial Flutter contain?. ### Response: S7.12-1.


Instruction: How many patients were analyzed from the SOS AF project?

Output: >10 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were analyzed from the SOS AF project?. ### Response: >10 000.


Instruction: What is the name of the project that measures atrial fibrillation and stroke risk?

Output: SOS AF project

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the project that measures atrial fibrillation and stroke risk?. ### Response: SOS AF project.


Instruction: Who is Glotzer TV, Daoud EG, Wyse DG?

Output: Glotzer TV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Glotzer TV, Daoud EG, Wyse DG?. ### Response: Glotzer TV.


Instruction: What is the TRENDS study?

Output: The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the TRENDS study?. ### Response: The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk.


Instruction: What predicts death and stroke?

Output: Atrial high rate episodes detected by pacemaker diagnostics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts death and stroke?. ### Response: Atrial high rate episodes detected by pacemaker diagnostics.


Instruction: What is the name of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial?

Output: MOST

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial?. ### Response: MOST.


Instruction: Circulation. 2003;107:1614-9. S7.12-4.

Output: M, et al. Device-detected atrial fibrillation and risk for stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2003;107:1614-9. S7.12-4.. ### Response: M, et al. Device-detected atrial fibrillation and risk for stroke.


Instruction: What is the title of the 2017 issue of CLINICAL STATEMENTS AND GUIDELINESCirculation?

Output: 136:e137–e161

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the 2017 issue of CLINICAL STATEMENTS AND GUIDELINESCirculation?. ### Response: 136:e137–e161.


Instruction: Who is the Chair of the CRITING GROUP?

Output: Mariell Jessup

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of the CRITING GROUP?. ### Response: Mariell Jessup.


Instruction: Who is Donald E. Casey Jr.?

Output: MD, MPH, MBA, FACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Donald E. Casey Jr.?. ### Response: MD, MPH, MBA, FACC.


Instruction: Who is Mark H. Drazner?

Output: MD, MSc, FACC, FAHA, FHFSA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Mark H. Drazner?. ### Response: MD, MSc, FACC, FAHA, FHFSA.


Instruction: Who is the MD, FACC, FAHA, FHFSA?

Output: Pamela N. Peterson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the MD, FACC, FAHA, FHFSA?. ### Response: Pamela N. Peterson.


Instruction: What is the name of the MD who is the PhD, RN, ACNS-BC?

Output: Cheryl Westlake

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the MD who is the PhD, RN, ACNS-BC?. ### Response: Cheryl Westlake.


Instruction: Which MD is the FAHA?

Output: Monica M. Colvin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which MD is the FAHA?. ### Response: Monica M. Colvin.


Instruction: Who developed the 2013 ACCF/AHA Guideline for the Management of Heart Disease?

Output: American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed the 2013 ACCF/AHA Guideline for the Management of Heart Disease?. ### Response: American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America.


Instruction: What was the name of the 2013 ACCF/AHA Guideline for the Management of Heart Failure?

Output: Focused Update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the 2013 ACCF/AHA Guideline for the Management of Heart Failure?. ### Response: Focused Update.


Instruction: What is the acronym for the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines?

Output: †ACC/AHA Task Force on Clinical Practice Guidelines Liaison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines?. ### Response: †ACC/AHA Task Force on Clinical Practice Guidelines Liaison.


Instruction: What is the acronym for the Heart Failure Society of America?

Output: FHFSA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Heart Failure Society of America?. ### Response: FHFSA.


Instruction: What is a term for angioedema?

Output: angiotensin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for angioedema?. ### Response: angiotensin.


Instruction: What is ivabradine?

Output: natriuretic peptides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ivabradine?. ### Response: natriuretic peptides.


Instruction: What are writing group members required to recuse themselves from voting on?

Output: sections to which their specific relationships with industry may apply

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are writing group members required to recuse themselves from voting on?. ### Response: sections to which their specific relationships with industry may apply.


Instruction: What is the name of the ACC/AHA Task Force on Clinical Practice Guidelines Liaison?

Output: American College of Cardiology/American Heart  Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACC/AHA Task Force on Clinical Practice Guidelines Liaison?. ### Response: American College of Cardiology/American Heart  Association.


Instruction: Who requests that this document be cited?

Output: The American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who requests that this document be cited?. ### Response: The American Heart Association.


Instruction: The American Heart Association requests that this document be cited as what?

Output: Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The American Heart Association requests that this document be cited as what?. ### Response: Task Force on Clinical Practice Guidelines.


Instruction: What is the focus of the 2017 update of the 2013 ACCF/AHA guideline for the management of heart failure?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the 2017 update of the 2013 ACCF/AHA guideline for the management of heart failure?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America.


Instruction: What was the name of the Task Force on Clinical Practice Guidelines and the Heart Failure Society of America?

Output: American College of Cardiology/American Heart  Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the Task Force on Clinical Practice Guidelines and the Heart Failure Society of America?. ### Response: American College of Cardiology/American Heart  Association.


Instruction: What is the name of the organization that is responsible for heart failure?

Output: Heart Failure Society of America

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that is responsible for heart failure?. ### Response: Heart Failure Society of America.


Instruction: When was this publication published?

Output: August 8, 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication published?. ### Response: August 8, 2017.


Instruction: Where can this publication be found?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can this publication be found?. ### Response: http://ahajournals.org.


Instruction: What is the 2013 AHA/ACC guideline on life-style management to reduce cardiovascular risk?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 AHA/ACC guideline on life-style management to reduce cardiovascular risk?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: ascular risk in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: ascular risk in adults.


Instruction: What is the 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults?

Output: guide-line

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults?. ### Response: guide-line.


Instruction: What was the report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Obesity Society?

Output: AHA/ACC/TOS guide-line for the management of overweight and obesity in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Obesity Society?. ### Response: AHA/ACC/TOS guide-line for the management of overweight and obesity in adults.


Instruction: What is the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction?

Output: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction?. ### Response: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.


Instruction: What was the report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

Output: ascular risk in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: ascular risk in adults.


Instruction: What is the 2014 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardio-vascular risk in adults?

Output: Stone NJ, Robinson J, Lichtenstein AH, et al. 2014 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardio-vascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardio-vascular risk in adults?. ### Response: Stone NJ, Robinson J, Lichtenstein AH, et al. 2014 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardio-vascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What was the report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: ascular risk in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: ascular risk in adults.


Instruction: What is the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology called?

Output: ESC Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology called?. ### Response: ESC Guidelines.


Instruction: What does ESC stand for?

Output: European Society of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ESC stand for?. ### Response: European Society of Cardiology.


Instruction: What is the acronym for the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

Output: ACCF/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: ACCF/AHA.


Instruction: In what year did the ACCF/AHA/HRS focus update become part of the 2008 guidelines for device-based therapy?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the ACCF/AHA/HRS focus update become part of the 2008 guidelines for device-based therapy?. ### Response: 2012.


Instruction: Who is a member of the Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

Output: O’Gara

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: O’Gara.


Instruction: What is the third universal definition of myo-cardial infarction?

Output: Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myo-cardial infarction. Circulation. 2012;126:2020–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the third universal definition of myo-cardial infarction?. ### Response: Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myo-cardial infarction. Circulation. 2012;126:2020–.


Instruction: How many intervention trials of BP lowering were included in the regression analysis?

Output: 31

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many intervention trials of BP lowering were included in the regression analysis?. ### Response: 31.


Instruction: How many patients with diabetes mellitus had a 13% decrease in the risk of stroke?

Output: ≈74 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with diabetes mellitus had a 13% decrease in the risk of stroke?. ### Response: ≈74 000.


Instruction: What was the decrease in risk for stroke for each 5-mm Hg reduc-tion in SBP?

Output: 13%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the decrease in risk for stroke for each 5-mm Hg reduc-tion in SBP?. ### Response: 13%.


Instruction: In ONTARGET, the benefits from lowering SBP to 130 mm Hg were driven mainly by what?

Output: better

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In ONTARGET, the benefits from lowering SBP to 130 mm Hg were driven mainly by what?. ### Response: better.


Instruction: What was unaffected and cardiovascular mortality was unchanged?

Output: MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was unaffected and cardiovascular mortality was unchanged?. ### Response: MI.


Instruction: What does inten-sive BP lowering to 130/80 mm Hg do not significantly decrease or increase?

Output: coronary morbidity or mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does inten-sive BP lowering to 130/80 mm Hg do not significantly decrease or increase?. ### Response: coronary morbidity or mortality.


Instruction: What might be predicted that a J curve would have a more dev-astating effect on elderly individuals?

Output: The Elderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be predicted that a J curve would have a more dev-astating effect on elderly individuals?. ### Response: The Elderly.


Instruction: Why is a nadir at higher pressures higher?

Output: greater likelihood of their having CAD and a lower coronary reserve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is a nadir at higher pressures higher?. ### Response: greater likelihood of their having CAD and a lower coronary reserve.


Instruction: How many studies have addressed CAD and a lower coronary reserve?

Output: Very few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have addressed CAD and a lower coronary reserve?. ### Response: Very few.


Instruction: What did an INVEST sub-study158 show a J-shaped relationship between?

Output: DBP and the primary outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did an INVEST sub-study158 show a J-shaped relationship between?. ### Response: DBP and the primary outcome.


Instruction: What is another name for nonfatal MI?

Output: nonfa-tal stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for nonfatal MI?. ### Response: nonfa-tal stroke.


Instruction: What was the nadir of nonfatal stroke?

Output: 75 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the nadir of nonfatal stroke?. ### Response: 75 mm Hg.


Instruction: How old were patients in HYVET randomized to receive treatment?

Output: >80 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old were patients in HYVET randomized to receive treatment?. ### Response: >80 years of age.


Instruction: How many mm Hg were randomized to receive treatment with indap-amide?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mm Hg were randomized to receive treatment with indap-amide?. ### Response: 15.


Instruction: What was added if necessary?

Output: perindopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was added if necessary?. ### Response: perindopril.


Instruction: How much did the active treatment group reduce in stroke and HF?

Output: 64%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did the active treatment group reduce in stroke and HF?. ### Response: 64%.


Instruction: What percentage reduction in HF had no significant effect on MI?

Output: 64%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage reduction in HF had no significant effect on MI?. ### Response: 64%.


Instruction: What is the target BP of HYVET?

Output: 150/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target BP of HYVET?. ### Response: 150/80 mm Hg.


Instruction: How many patients received treatment for HF after 2 years?

Output: 64%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients received treatment for HF after 2 years?. ### Response: 64%.


Instruction: What is the recommended goal BP in people with uncomplicated hypertension?

Output: <140/90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended goal BP in people with uncomplicated hypertension?. ### Response: <140/90 mm Hg.


Instruction: What does the ACC Foundation/AHA 2011 expert consensus document state?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ACC Foundation/AHA 2011 expert consensus document state?. ### Response: hypertension.


Instruction: What is the target SBP for uncomplicated hypertension?

Output: <140/90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target SBP for uncomplicated hypertension?. ### Response: <140/90 mm Hg.


Instruction: What is based on expert opinion rather than data from RCTs?

Output: target for elderly patients with hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is based on expert opinion rather than data from RCTs?. ### Response: target for elderly patients with hypertension.


Instruction: What is the target of 140/90mm Hg for this age group?

Output: <140/90 mm Hg. However, this target for elderly patients with hypertension is based on expert opinion rather than on data from RCTs [randomized, controlled trials], and it is unclear whether the target SBP should be the same in 65 to 79 year old versus older patients.”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target of 140/90mm Hg for this age group?. ### Response: <140/90 mm Hg. However, this target for elderly patients with hypertension is based on expert opinion rather than on data from RCTs [randomized, controlled trials], and it is unclear whether the target SBP should be the same in 65 to 79 year old versus older patients.”.


Instruction: What may be associated with better stroke out-comes except in the case of PROFESS?

Output: Lower SBP values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with better stroke out-comes except in the case of PROFESS?. ### Response: Lower SBP values.


Instruction: The evidence for CAD outcomes is what?

Output: equivocal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The evidence for CAD outcomes is what?. ### Response: equivocal.


Instruction: The evidence for CAD outcomes is equivocal and what is inconsistent?

Output: Lower SBP values may be associated with better stroke out-comes except in the case of PROFESS, and the evidence for CAD outcomes is equivocal. The evidence that excessive low-ering of DBP may compromise cardiac outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The evidence for CAD outcomes is equivocal and what is inconsistent?. ### Response: Lower SBP values may be associated with better stroke out-comes except in the case of PROFESS, and the evidence for CAD outcomes is equivocal. The evidence that excessive low-ering of DBP may compromise cardiac outcomes.


Instruction: The evidence that excessive low-ering of DBP may compromise cardiac outcomes is known as what?

Output: the J curve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The evidence that excessive low-ering of DBP may compromise cardiac outcomes is known as what?. ### Response: the J curve.


Instruction: Epidemiological and clinical trial evidence both support and refute the existence of what for DBP?

Output: a J curve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Epidemiological and clinical trial evidence both support and refute the existence of what for DBP?. ### Response: a J curve.


Instruction: How many ED personnel can identify patients with a history of hypertension but nonadherence to their medication regimen who need to resume their previous medications?

Output: 221,903

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ED personnel can identify patients with a history of hypertension but nonadherence to their medication regimen who need to resume their previous medications?. ### Response: 221,903.


Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3799to outpatient primary care?

Output: 221,903 ED personnel can identify patients with a history of hyperten-sion but nonadherence to their medication regimen who need to resume their previous medications. ED screening for hyper -tension is feasible and cost-effective. Once hypertensive patients are identified, ED personnel can educate on and encourage healthy lifestyles to address their hypertension and the impor -tance of outpatient follow-up, in accordance with the current Joint National Committee 8 outpatient guidelines.219,896,904

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3799to outpatient primary care?. ### Response: 221,903 ED personnel can identify patients with a history of hyperten-sion but nonadherence to their medication regimen who need to resume their previous medications. ED screening for hyper -tension is feasible and cost-effective. Once hypertensive patients are identified, ED personnel can educate on and encourage healthy lifestyles to address their hypertension and the impor -tance of outpatient follow-up, in accordance with the current Joint National Committee 8 outpatient guidelines.219,896,904.


Instruction: What is feasible and cost-effective?

Output: ED screening for hyper -tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is feasible and cost-effective?. ### Response: ED screening for hyper -tension.


Instruction: What can ED personnel educate and encourage to address their hypertension?

Output: healthy lifestyles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can ED personnel educate and encourage to address their hypertension?. ### Response: healthy lifestyles.


Instruction: How much has the incidence of diabetes mellitus more than doubled over the last 2 decades?

Output: doubled

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much has the incidence of diabetes mellitus more than doubled over the last 2 decades?. ### Response: doubled.


Instruction: How many people with diabetes remain undiagnosed?

Output: millions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people with diabetes remain undiagnosed?. ### Response: millions.


Instruction: What is the prevalence of undiagnosed diabetes mellitus in the US population?

Output: 2.8%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of undiagnosed diabetes mellitus in the US population?. ### Response: 2.8%..


Instruction: According to the National Health and Nutrition Examination Survey, what percentage of the population has diabetes?

Output: 2.8%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: According to the National Health and Nutrition Examination Survey, what percentage of the population has diabetes?. ### Response: 2.8%..


Instruction: In addition to hemoglobin A1c, what is fasting plasma glucose?

Output: capillary blood glucose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to hemoglobin A1c, what is fasting plasma glucose?. ### Response: capillary blood glucose.


Instruction: What is not currently recommended by emergency medicine societies or other healthcare agencies?

Output: Unselected screen-ing by capillary blood glucose or hemoglobin A1c measure-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not currently recommended by emergency medicine societies or other healthcare agencies?. ### Response: Unselected screen-ing by capillary blood glucose or hemoglobin A1c measure-ment.


Instruction: What may be feasible but remains to be determined whether such screening is cost-effective?

Output: point-of-care glucose and hemoglobin A1c testing of ED patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be feasible but remains to be determined whether such screening is cost-effective?. ### Response: point-of-care glucose and hemoglobin A1c testing of ED patients.


Instruction: What do emergency physi-cians support?

Output: improved recognition and referral for hyper -glycemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do emergency physi-cians support?. ### Response: improved recognition and referral for hyper -glycemia.


Instruction: What do patients with diabetes mellitus commonly use EDs for?

Output: acute care of complications related to diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients with diabetes mellitus commonly use EDs for?. ### Response: acute care of complications related to diabetes mellitus.


Instruction: What is a leading cause of preventable deaths in the United States?

Output: cigarette smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a leading cause of preventable deaths in the United States?. ### Response: cigarette smoking.


Instruction: How many deaths are prevented by cigarette smoking each year?

Output: 1 of every 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths are prevented by cigarette smoking each year?. ### Response: 1 of every 5.


Instruction: How many deaths does the ED account for each year?

Output: 219,896,904

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths does the ED account for each year?. ### Response: 219,896,904.


Instruction: What does the American College of Emergency Physicians recommend for smoking cessation?

Output: ED interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American College of Emergency Physicians recommend for smoking cessation?. ### Response: ED interventions.


Instruction: What do smoking-related illnesses lead to in ED visits?

Output: teachable moments” to encourage cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do smoking-related illnesses lead to in ED visits?. ### Response: teachable moments” to encourage cessation.


Instruction: What are smoking related illnesses used for?

Output: ED visits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are smoking related illnesses used for?. ### Response: ED visits.


Instruction: How are oral antithrombotic agents used?

Output: for the prevention of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are oral antithrombotic agents used?. ### Response: for the prevention of stroke.


Instruction: What remains a cornerstone of stroke prevention?

Output: oral antithrombotic agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains a cornerstone of stroke prevention?. ### Response: oral antithrombotic agents.


Instruction: What survey revealed an 88% increase in US ED visits for AF?

Output: US National Hospital Ambulatory Medical Care Survey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What survey revealed an 88% increase in US ED visits for AF?. ### Response: US National Hospital Ambulatory Medical Care Survey.


Instruction: What has been largely unsuccessful in improving symptoms of claudication or walking dis-tance in patients with PAD?

Output: Hypertension  June 2015blockers, and direct vasodilators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been largely unsuccessful in improving symptoms of claudication or walking dis-tance in patients with PAD?. ### Response: Hypertension  June 2015blockers, and direct vasodilators.


Instruction: What do -blockers constrict resistance vessels?

Output: β-blockers constrict resistance vessels, a meta-analysis concluded that this drug class does not worsen intermittent claudication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do -blockers constrict resistance vessels?. ### Response: β-blockers constrict resistance vessels, a meta-analysis concluded that this drug class does not worsen intermittent claudication.


Instruction: What can be used in PAD patients with compelling indications for their use such as CAD or HF?

Output: β-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used in PAD patients with compelling indications for their use such as CAD or HF?. ### Response: β-blockers.


Instruction: What should be administered to hyperten-sive patients with lower-extremity PAD?

Output: Antihypertensive therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be administered to hyperten-sive patients with lower-extremity PAD?. ### Response: Antihypertensive therapy.


Instruction: What should be given to hypertensive patients with lower-extremity PAD to achieve a goal of 140/90 mm Hg (nondiabetics)?

Output: Antihypertensive therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given to hypertensive patients with lower-extremity PAD to achieve a goal of 140/90 mm Hg (nondiabetics)?. ### Response: Antihypertensive therapy.


Instruction: What should therapy be administered to to reduce the risk of MI, stroke, congestive HF, and cardiovascular death?

Output: Antihypertensive therapy should be administered to hyperten-sive patients with lower-extremity PAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should therapy be administered to to reduce the risk of MI, stroke, congestive HF, and cardiovascular death?. ### Response: Antihypertensive therapy should be administered to hyperten-sive patients with lower-extremity PAD.


Instruction: What is a Level of Evidence A?

Output: Antihypertensive therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Level of Evidence A?. ### Response: Antihypertensive therapy.


Instruction: What are effective antihypertensive agents?

Output: β-adrenergic blocking drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are effective antihypertensive agents?. ### Response: β-adrenergic blocking drugs.


Instruction: What is CKD defined as?

Output: kidney damage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD defined as?. ### Response: kidney damage.


Instruction: How long has there been a steady increase in the prevalence of?

Output: ≥ 3 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has there been a steady increase in the prevalence of?. ### Response: ≥ 3 months.


Instruction: What is the glomerular filtration rate to?

Output: <60 mL· min−1·1.73 m−2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the glomerular filtration rate to?. ### Response: <60 mL· min−1·1.73 m−2.


Instruction: What is the glomerular filtration rate for 3 months?

Output: <60 mL· min−1·1.73 m−2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the glomerular filtration rate for 3 months?. ### Response: <60 mL· min−1·1.73 m−2.


Instruction: What is kidney failure defined as?

Output: a glomer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is kidney failure defined as?. ### Response: a glomer.


Instruction: How many patients in the US are affected by kidney failure?

Output: >525 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients in the US are affected by kidney failure?. ### Response: >525 000.


Instruction: How many people in the US are on long-term hemodialysis?

Output: 65%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people in the US are on long-term hemodialysis?. ### Response: 65%.


Instruction: What is the preva-lence of hypertension in hypertensive patients?

Output: 28%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preva-lence of hypertension in hypertensive patients?. ### Response: 28%.


Instruction: Cardiovascular death is more likely than what in patients with CKD?

Output: progression to end-stage renal disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cardiovascular death is more likely than what in patients with CKD?. ### Response: progression to end-stage renal disease.


Instruction: What is the leading cause of death in patients with end-stage renal dis-ease?

Output: CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the leading cause of death in patients with end-stage renal dis-ease?. ### Response: CVD.


Instruction: How many times higher is CVD in patients on dialysis than in the general population?

Output: 5 to 30

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times higher is CVD in patients on dialysis than in the general population?. ### Response: 5 to 30.


Instruction: In patients with lower stages of CKD, the risk of CVD is what?

Output: increased independently of other risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with lower stages of CKD, the risk of CVD is what?. ### Response: increased independently of other risk factors.


Instruction: What is a leading cause of renal failure?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a leading cause of renal failure?. ### Response: hypertension.


Instruction: What is the risk of CVD and all-cause death increased by even the smallest degree of?

Output: albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of CVD and all-cause death increased by even the smallest degree of?. ### Response: albuminuria.


Instruction: What are the BP goals in patients with CKD and microalbuminuria lower than in the general popula-tion?

Output: target the same as that in patients with estab-lished CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the BP goals in patients with CKD and microalbuminuria lower than in the general popula-tion?. ### Response: target the same as that in patients with estab-lished CAD.


Instruction: What is a target the same as in estab-lished CAD?

Output: BP goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a target the same as in estab-lished CAD?. ### Response: BP goals.


Instruction: Recent investigations have shown that standard treatments for cardiovascular risk factors are what?

Output: statin therapy, ACE inhibitors, ARBs, and antiplatelet agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent investigations have shown that standard treatments for cardiovascular risk factors are what?. ### Response: statin therapy, ACE inhibitors, ARBs, and antiplatelet agents.


Instruction: What are statins, ACE inhibitors, ARBs, and antiplatelet agents equally effective at in patients with CKD?

Output: risk reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are statins, ACE inhibitors, ARBs, and antiplatelet agents equally effective at in patients with CKD?. ### Response: risk reduction.


Instruction: What is another term for patients who are not on dialysis?

Output: CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for patients who are not on dialysis?. ### Response: CKD.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the DOI for the February 2, 2021 e213CLINICAL STATEMENTS AND GUIDELINES 9. Prendergast BD. Diagnostic criteria and problems in infective endocarditis. 2004;90:611–3.

Output: 10.1161/CIR.0000000000000923

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI for the February 2, 2021 e213CLINICAL STATEMENTS AND GUIDELINES 9. Prendergast BD. Diagnostic criteria and problems in infective endocarditis. 2004;90:611–3.. ### Response: 10.1161/CIR.0000000000000923.


Instruction: What criteria is used in patients with sus-pected infective endocarditis and negative transesophageal echocardio-grams?

Output: Duke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria is used in patients with sus-pected infective endocarditis and negative transesophageal echocardio-grams?. ### Response: Duke.


Instruction: What is the name of the study that studies the clinical presentation, etiology, and outcome of infected endeocarditic disease in the 21st century?

Output: International Collaboration on Endocarditis-Prospective Cohort Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that studies the clinical presentation, etiology, and outcome of infected endeocarditic disease in the 21st century?. ### Response: International Collaboration on Endocarditis-Prospective Cohort Study.


Instruction: What is the International Collaboration on Endocarditis-Prospective Cohort Study?

Output: Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the International Collaboration on Endocarditis-Prospective Cohort Study?. ### Response: Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century.


Instruction: What year did Arch Intern Med publish 169:463–73?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Arch Intern Med publish 169:463–73?. ### Response: 2009.


Instruction: How did Haldar SM, O’Gara PT diagnose and manage infective endocardiitis?

Output: diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Haldar SM, O’Gara PT diagnose and manage infective endocardiitis?. ### Response: diagnosis.


Instruction: Infective endocarditis. 2006;31:274–352. 14. Mügge A, Daniel WG, Frank G, et al. Echocardiography in what?

Output: infective endo-carditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis. 2006;31:274–352. 14. Mügge A, Daniel WG, Frank G, et al. Echocardiography in what?. ### Response: infective endo-carditis.


Instruction: What approach is used to assess prognostic implications of vegetation size deter?

Output: transthoracic versus transesophageal echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What approach is used to assess prognostic implications of vegetation size deter?. ### Response: transthoracic versus transesophageal echocardiography.


Instruction: What is the role of two-dimensional echocar -diology in the diagnosis of infective endocarditis?

Output: corrected

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of two-dimensional echocar -diology in the diagnosis of infective endocarditis?. ### Response: corrected.


Instruction: What does a negative transthoracic echocardiogram obviates the need for?

Output: transesophageal echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a negative transthoracic echocardiogram obviates the need for?. ### Response: transesophageal echocardiography.


Instruction: What type of echocardiography is used in patients with suspected native valve active infective endocarditis?

Output: Duke criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of echocardiography is used in patients with suspected native valve active infective endocarditis?. ### Response: Duke criteria.


Instruction: What is the name of the study that evaluated the use of transthoracic echocardiog-raphy?

Output: infective endocarditis screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the use of transthoracic echocardiog-raphy?. ### Response: infective endocarditis screening.


Instruction: In what year did Can J Cardiol. 2009:25:703-5?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Can J Cardiol. 2009:25:703-5?. ### Response: 1991.


Instruction: How does echocardiography diagnose culture-negative endocarditis?

Output: screen-ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does echocardiography diagnose culture-negative endocarditis?. ### Response: screen-ing.


Instruction: What is the name of the study that focuses on infective endocar -ditis in South Med J?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that focuses on infective endocar -ditis in South Med J?. ### Response: 1999.


Instruction: How is the use of echocardiog-raphy used in the diagnosis of infection?

Output: Judicious

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the use of echocardiog-raphy used in the diagnosis of infection?. ### Response: Judicious.


Instruction: When was the Circulation. 1981?

Output: 1981;64:641–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation. 1981?. ### Response: 1981;64:641–.


Instruction: What does transesophageal echocardiog-raphy do in diagnosis of infective endocarditis?

Output: reassessment of prognostic implications of vegetation size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does transesophageal echocardiog-raphy do in diagnosis of infective endocarditis?. ### Response: reassessment of prognostic implications of vegetation size.


Instruction: When was the Chest 105:377-82 published?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Chest 105:377-82 published?. ### Response: 1994.


Instruction: What did Erbel R, Rohmann S, Drexler M, et al. say improved diagnostic value of echo-cardiography in patients with infectious endo cardiotis by?

Output: transoesophageal approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Erbel R, Rohmann S, Drexler M, et al. say improved diagnostic value of echo-cardiography in patients with infectious endo cardiotis by?. ### Response: transoesophageal approach.


Instruction: What is the prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia?

Output: Prevalence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia?. ### Response: Prevalence.


Instruction: When did Eur J Echocardiogr. 2011:12:414–20?

Output: 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Echocardiogr. 2011:12:414–20?. ### Response: 23.


Instruction: What is sensitivity of transthoracic versus transesophageal echocardiography for?

Output: the detection of native valve veg-etations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is sensitivity of transthoracic versus transesophageal echocardiography for?. ### Response: the detection of native valve veg-etations.


Instruction: Transthoracic versus transesophageal echocardiography for the detection of native valve veg-etations in the modern era?

Output: Sensitivity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Transthoracic versus transesophageal echocardiography for the detection of native valve veg-etations in the modern era?. ### Response: Sensitivity.


Instruction: J Am Soc Echocardiogr. 2003;16:67-70.

Output: 23. Reynolds HR, Jagen MA, Tunick PA, et al. Sensitivity of transthoracic versus transesophageal echocardiography for the detection of native valve veg-etations in the modern era. J Am Soc Echocardiogr. 2003;16:67–70. 24

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Am Soc Echocardiogr. 2003;16:67-70.. ### Response: 23. Reynolds HR, Jagen MA, Tunick PA, et al. Sensitivity of transthoracic versus transesophageal echocardiography for the detection of native valve veg-etations in the modern era. J Am Soc Echocardiogr. 2003;16:67–70. 24.


Instruction: What is e100 Hypertension June 2018 S9.7-12?

Output: Dose-dependent arterial destiffening and inward remodeling after olmesartan in hypertensives with metabolic syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is e100 Hypertension June 2018 S9.7-12?. ### Response: Dose-dependent arterial destiffening and inward remodeling after olmesartan in hypertensives with metabolic syndrome.


Instruction: Laurent S, Boutouyrie P; Vascular Mechanism Collaboration. Dose-dependent arterial destiffening and inward remodeling after olmesartan in hypertensives with metabolic syndrome?

Output: Hypertension  June 2018 S9.7-12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Laurent S, Boutouyrie P; Vascular Mechanism Collaboration. Dose-dependent arterial destiffening and inward remodeling after olmesartan in hypertensives with metabolic syndrome?. ### Response: Hypertension  June 2018 S9.7-12.


Instruction: What is the connection between obesity and hypertension?

Output: Metabolic syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the connection between obesity and hypertension?. ### Response: Metabolic syndrome.


Instruction: What is a quiz 160.9.8 about?

Output: Atrial Fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a quiz 160.9.8 about?. ### Response: Atrial Fibrillation.


Instruction: How does prevention of atrial fibrillation work?

Output: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does prevention of atrial fibrillation work?. ### Response: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers.


Instruction: What is renin-angiotensin system inhibitors used for?

Output: essential hypertensive patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is renin-angiotensin system inhibitors used for?. ### Response: essential hypertensive patients.


Instruction: What is the name of the meta-analysis of randomized controlled trials conducted on essential hypertensive patients?

Output: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of randomized controlled trials conducted on essential hypertensive patients?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.


Instruction: What are electrophysiologic and electroanatomic changes in the human atrium associated with?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are electrophysiologic and electroanatomic changes in the human atrium associated with?. ### Response: age.


Instruction: What is the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.


Instruction: The American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.

Output: AHA/ACC/HRS guideline for the management of patients with atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.. ### Response: AHA/ACC/HRS guideline for the management of patients with atrial fibrillation.


Instruction: What is the value of the CHA2DS2-V ASc score for refining stroke risk stratification in patients with atrial fibrillation with a CHADS2 score?

Output: 0–1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of the CHA2DS2-V ASc score for refining stroke risk stratification in patients with atrial fibrillation with a CHADS2 score?. ### Response: 0–1.


Instruction: What is the CHADS2 score for atrial fibrillation?

Output: 0–1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CHADS2 score for atrial fibrillation?. ### Response: 0–1.


Instruction: What is a risk factor for complications and potential therapeutic target?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for complications and potential therapeutic target?. ### Response: hypertension.


Instruction: How many patients were enrolled in a national-wide cohort study?

Output: S9.8-6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in a national-wide cohort study?. ### Response: S9.8-6.


Instruction: What is the name of the Swedish Trial in Old Patients with Hypertension-2 study?

Output: The Swedish Trial in Old Patients with Hypertension-2 study. Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Swedish Trial in Old Patients with Hypertension-2 study?. ### Response: The Swedish Trial in Old Patients with Hypertension-2 study. Lancet.


Instruction: What is Julius S, Kjeldsen SE, Weber M, et al.?

Output: Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the V ALUE randomised trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Julius S, Kjeldsen SE, Weber M, et al.?. ### Response: Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the V ALUE randomised trial.


Instruction: In what year did the Lancet issue 354:1751–6?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the Lancet issue 354:1751–6?. ### Response: 1999.


Instruction: What is the name of the randomised trial of valsartan and amlodipine in hypertensive patients at high cardiovascular risk?

Output: V ALUE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial of valsartan and amlodipine in hypertensive patients at high cardiovascular risk?. ### Response: V ALUE.


Instruction: What does the V ALUE trial involve?

Output: Outcomes in hypertensive patients at high cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the V ALUE trial involve?. ### Response: Outcomes in hypertensive patients at high cardiovascular risk.


Instruction: When was the Lancet 363:2022-31?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet 363:2022-31?. ### Response: 2004.


Instruction: How does angiotensin II receptor blockade reduce new-onset atrial fibrillation?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does angiotensin II receptor blockade reduce new-onset atrial fibrillation?. ### Response: stroke.


Instruction: What does blockade reduce compared to atenolol?

Output: new-onset atrial fibrillation and subsequent stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does blockade reduce compared to atenolol?. ### Response: new-onset atrial fibrillation and subsequent stroke.


Instruction: What does LIFE stand for?

Output: Losartan Intervention For End Point Reduction in Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LIFE stand for?. ### Response: Losartan Intervention For End Point Reduction in Hypertension.


Instruction: When was the LIFE study conducted?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the LIFE study conducted?. ### Response: 2005.


Instruction: What does ALLHAT stand for?

Output: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ALLHAT stand for?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.


Instruction: What is the J Am Coll Cardiol. 2009;54:2023-31?

Output: S9.8-11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2009;54:2023-31?. ### Response: S9.8-11.


Instruction: Who published the 2014 Stable Ischemic Heart Disease Focused Update 1757?

Output: Fihn et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2014 Stable Ischemic Heart Disease Focused Update 1757?. ### Response: Fihn et al.


Instruction: How many patients were randomly assigned to receive DES or CABG?

Output: 1800

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were randomly assigned to receive DES or CABG?. ### Response: 1800.


Instruction: What is MACCE?

Output: Major adverse cardiac and cerebrovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MACCE?. ### Response: Major adverse cardiac and cerebrovascular events.


Instruction: What percentage of patients had received CABG?

Output: 26.9%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients had received CABG?. ### Response: 26.9%.


Instruction: How many patients had undergone DES implantation?

Output: 37.3%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had undergone DES implantation?. ### Response: 37.3%.


Instruction: What was the rate of death and stroke?

Output: 16.7% versus 20.8%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the rate of death and stroke?. ### Response: 16.7% versus 20.8%;.


Instruction: What was more likely to occur with DES implantation?

Output: MACCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was more likely to occur with DES implantation?. ### Response: MACCE.


Instruction: At 5 years of follow-up, what occurred in 26.9% of patients?

Output: MACCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At 5 years of follow-up, what occurred in 26.9% of patients?. ### Response: MACCE.


Instruction: How many years of follow-up did MACCE occur in patients who had received CABG?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of follow-up did MACCE occur in patients who had received CABG?. ### Response: 5.


Instruction: What was the combined endpoint of death, stroke, or MI?

Output: lower in CABG-treated patients than in DES-treated patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the combined endpoint of death, stroke, or MI?. ### Response: lower in CABG-treated patients than in DES-treated patients.


Instruction: In SYNTAX, what was the extent of CAD?

Output: SYNTAX score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In SYNTAX, what was the extent of CAD?. ### Response: SYNTAX score.


Instruction: How was the extent of CAD assessed?

Output: using the SYNTAX score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the extent of CAD assessed?. ### Response: using the SYNTAX score.


Instruction: What is the SYNTAX score based on?

Output: location, severity, and extent of coronary stenoses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the SYNTAX score based on?. ### Response: location, severity, and extent of coronary stenoses.


Instruction: A low score indicates less complicated what?

Output: anatomic CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A low score indicates less complicated what?. ### Response: anatomic CAD.


Instruction: What was a low score defined as?

Output: ≤ 22

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a low score defined as?. ### Response: ≤ 22.


Instruction: What was an intermediate score defined to be?

Output: 23 to 32

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was an intermediate score defined to be?. ### Response: 23 to 32.


Instruction: A high score was defined as what?

Output: ≥ 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A high score was defined as what?. ### Response: ≥ 33.


Instruction: The occurrence of MACCE correlated with the SYNTAX score for what patients?

Output: DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The occurrence of MACCE correlated with the SYNTAX score for what patients?. ### Response: DES.


Instruction: What was the primary endpoint for CABG and DES in those with a low SYNTAX score?

Output: 12-month follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary endpoint for CABG and DES in those with a low SYNTAX score?. ### Response: 12-month follow-up.


Instruction: What occurred more often after DES implantation than after CABG?

Output: MACCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What occurred more often after DES implantation than after CABG?. ### Response: MACCE.


Instruction: At 3 years of follow-up, the mortality rate was greater in subjects with what?

Output: 3-vessel CAD treated with DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At 3 years of follow-up, the mortality rate was greater in subjects with what?. ### Response: 3-vessel CAD treated with DES.


Instruction: What was the mortality rate of subjects with 3-vessel CAD treated with DES versus those treated with CABG?

Output: 6.2%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mortality rate of subjects with 3-vessel CAD treated with DES versus those treated with CABG?. ### Response: 6.2%.


Instruction: The mortality rate was greater in subjects treated with what type of CAD?

Output: 3-vessel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The mortality rate was greater in subjects treated with what type of CAD?. ### Response: 3-vessel.


Instruction: What increased with an increasing SYNTAX score at 5-year follow-up?

Output: MACCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increased with an increasing SYNTAX score at 5-year follow-up?. ### Response: MACCE.


Instruction: What is the utility of the SYNTAX score in everyday clini-cal practice?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the utility of the SYNTAX score in everyday clini-cal practice?. ### Response: uncertain.


Instruction: What are the survival rates of patients undergoing PCI or CABG with relatively uncomplicated and lesser degrees of CAD comparable to?

Output: comparable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the survival rates of patients undergoing PCI or CABG with relatively uncomplicated and lesser degrees of CAD comparable to?. ### Response: comparable.


Instruction: What is preferable for patients with complex and diffuse CAD?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preferable for patients with complex and diffuse CAD?. ### Response: CABG.


Instruction: What percentage of patients undergo coronary angiography?

Output: approxi-mately 4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients undergo coronary angiography?. ### Response: approxi-mately 4%.


Instruction: How many patients have left main coronary artery?

Output: 4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients have left main coronary artery?. ### Response: 4%.


Instruction: What percentage of patients have significant stenoses in other epi-cardial arteries?

Output: >80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have significant stenoses in other epi-cardial arteries?. ### Response: >80%.


Instruction: How long after revascularization are major clinical outcomes similar?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after revascularization are major clinical outcomes similar?. ### Response: 1 year.


Instruction: How long after revas-cularization are mortality rates similar with PCI or CABG?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after revas-cularization are mortality rates similar with PCI or CABG?. ### Response: 1 year.


Instruction: At 1, 2, and 5 years of follow-up, mortality rates are similar with what?

Output: PCI or CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At 1, 2, and 5 years of follow-up, mortality rates are similar with what?. ### Response: PCI or CABG.