Instruction: What time is needed for quiet during the rest and measurement periods?

Output: ext ra time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What time is needed for quiet during the rest and measurement periods?. ### Response: ext ra time.


Instruction: There may be resistance to incorporating fully automated blood pressure technique in practice because it requires time not speaking with the patient and allowing for rest and how many mea surements?

Output: several

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There may be resistance to incorporating fully automated blood pressure technique in practice because it requires time not speaking with the patient and allowing for rest and how many mea surements?. ### Response: several.


Instruction: How long is the average mea surement?

Output: seven to eight minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the average mea surement?. ### Response: seven to eight minutes.


Instruction: What is the main concern for busy clinic staff to incorporate the automated office blood pressure technique?

Output: the time required

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the main concern for busy clinic staff to incorporate the automated office blood pressure technique?. ### Response: the time required.


Instruction: What is AOBP?

Output: automated office blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AOBP?. ### Response: automated office blood pressure.


Instruction: What allows staff to attend to other patients or tasks during this time?

Output: automated office blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What allows staff to attend to other patients or tasks during this time?. ### Response: automated office blood pressure.


Instruction: How did patients describe the patient focus group?

Output: the following

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did patients describe the patient focus group?. ### Response: the following.


Instruction: What did some patients experience when their blood pressure was measured by a machine in the office setting?

Output: pain and uncomfortable pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some patients experience when their blood pressure was measured by a machine in the office setting?. ### Response: pain and uncomfortable pressure.


Instruction: How many times was the blood pressure taken in an office setting when the machine was used?

Output: twice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times was the blood pressure taken in an office setting when the machine was used?. ### Response: twice.


Instruction: What did the patient experience when they were measured by the machine?

Output: pain and uncomfortable pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the patient experience when they were measured by the machine?. ### Response: pain and uncomfortable pressure.


Instruction: How often should patients take their blood pressure readings in the office?

Output: twice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often should patients take their blood pressure readings in the office?. ### Response: twice.


Instruction: What was the first reading of blood pressure rarely accurate?

Output: blood pressure had to be taken twice when in the office setting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the first reading of blood pressure rarely accurate?. ### Response: blood pressure had to be taken twice when in the office setting.


Instruction: Patients felt the readings were inaccurate in what setting?

Output: clinical practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients felt the readings were inaccurate in what setting?. ### Response: clinical practice.


Instruction: What is the second FDA-approved P2Y12receptor in -hibitor for use in ACS?

Output: Prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the second FDA-approved P2Y12receptor in -hibitor for use in ACS?. ### Response: Prasugrel.


Instruction: Prasugrel requires a singleCYP-dependent step for its oxidation to what?

Output: the active metabolite

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prasugrel requires a singleCYP-dependent step for its oxidation to what?. ### Response: the active metabolite.


Instruction: How many observational studies have demonstrated nosignificant decrease in plasma concentrations or plateletinhibition?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many observational studies have demonstrated nosignificant decrease in plasma concentrations or plateletinhibition?. ### Response: 2.


Instruction: What is the latest FDA-approved P2Y12receptor inhibitor?

Output: ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the latest FDA-approved P2Y12receptor inhibitor?. ### Response: ticagrelor.


Instruction: What does ticagrelor do?

Output: reversible, direct-acting oral antago-nist of the P2Y12receptor that does not require transformationto an active metabolite

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ticagrelor do?. ### Response: reversible, direct-acting oral antago-nist of the P2Y12receptor that does not require transformationto an active metabolite.


Instruction: What does not require transformationto an active metabolite?

Output: ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not require transformationto an active metabolite?. ### Response: ticagrelor.


Instruction: When did the FDA announce a "Boxed Warning" about the diminished effectiveness of clopidogrel inpatients with an impaired ability to convert the drug into itsactive form?

Output: March12, 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the FDA announce a "Boxed Warning" about the diminished effectiveness of clopidogrel inpatients with an impaired ability to convert the drug into itsactive form?. ### Response: March12, 2010.


Instruction: What has been much interest in whetherclinicians should perform routine testing in patients being treated with clopidogral?

Output: 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been much interest in whetherclinicians should perform routine testing in patients being treated with clopidogral?. ### Response: 14.


Instruction: Who should perform routine testing in patients treated with clopidogrel?

Output: clinicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should perform routine testing in patients treated with clopidogrel?. ### Response: clinicians.


Instruction: What could routine testing be for?

Output: genetic variants of the CYP2C19 allele

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could routine testing be for?. ### Response: genetic variants of the CYP2C19 allele.


Instruction: Who summarizes the issues surrounding clopi-dogrel and the use of genotype testing?

Output: ACCF/AHA ClopidogrelClinical Alert

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who summarizes the issues surrounding clopi-dogrel and the use of genotype testing?. ### Response: ACCF/AHA ClopidogrelClinical Alert.


Instruction: What could be used for routine platelet function testing?

Output: genetic variants of the CYP2C19 allele

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be used for routine platelet function testing?. ### Response: genetic variants of the CYP2C19 allele.


Instruction: When was 20882 circulated?

Output: August 14, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was 20882 circulated?. ### Response: August 14, 2012.


Instruction: What does the Work Group not recommend?

Output: one over another

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Work Group not recommend?. ### Response: one over another.


Instruction: What are the commonly used risk calculators that providers should consider?

Output: to calculate the 10 -year risk and determine  the need for lipid- lowering medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the commonly used risk calculators that providers should consider?. ### Response: to calculate the 10 -year risk and determine  the need for lipid- lowering medication.


Instruction: What should providers consider when selecting a risk calculator?

Output: their patient population  characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should providers consider when selecting a risk calculator?. ### Response: their patient population  characteristics.


Instruction: What is the potential for over - or under -estimation of CV risk?

Output: 22 – 24%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the potential for over - or under -estimation of CV risk?. ### Response: 22 – 24%.


Instruction: What percentage of CV risk is estimated with each risk calculator?

Output: 22 – 24%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of CV risk is estimated with each risk calculator?. ### Response: 22 – 24%.


Instruction: What may result in over- or under-treatment?

Output: over - or under -estimation of 22 – 24% of CV risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may result in over- or under-treatment?. ### Response: over - or under -estimation of 22 – 24% of CV risk.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the name of the guideline that will be published in 2021?

Output: ACC/AHA Guideline for the Management of Valvular Heart Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline that will be published in 2021?. ### Response: ACC/AHA Guideline for the Management of Valvular Heart Disease.


Instruction: What is the Loire Valley Atrial Fibrillation Project?

Output: Oral anticoagulation, stroke and thromboembolism in patients with atrial fibrillation and valve bioprosthesis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Loire Valley Atrial Fibrillation Project?. ### Response: Oral anticoagulation, stroke and thromboembolism in patients with atrial fibrillation and valve bioprosthesis.


Instruction: When was the DAWA Pilot Study conducted?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the DAWA Pilot Study conducted?. ### Response: 2016.


Instruction: How many patients were treated with Dabigatran and Warfarin?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with Dabigatran and Warfarin?. ### Response: 20.


Instruction: Atrial Fibrillation Postoperatively: DAWA Pilot Study. Drugs R D. 2016;16:149–54.

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial Fibrillation Postoperatively: DAWA Pilot Study. Drugs R D. 2016;16:149–54.. ### Response: 20.


Instruction: Non-vitamin K antagonist oral anticoagulants versus warfarin in patients with atrial fibrillation and valvular heart disease.

Output: Comparative effectiveness and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Non-vitamin K antagonist oral anticoagulants versus warfarin in patients with atrial fibrillation and valvular heart disease.. ### Response: Comparative effectiveness and safety.


Instruction: Int J Cardiol 2016;209:181–3.

Output: atrial fibrillation and valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol 2016;209:181–3.. ### Response: atrial fibrillation and valvular heart disease.


Instruction: Int J Cardiol. 2016;209:181–3. 22. Kim JY, Kim S-H, Myong J-P, et al. Outcomes of direct oral anticoagulants in patients with mitral stenosis.

Output: atrial fibrillation and valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol. 2016;209:181–3. 22. Kim JY, Kim S-H, Myong J-P, et al. Outcomes of direct oral anticoagulants in patients with mitral stenosis.. ### Response: atrial fibrillation and valvular heart disease.


Instruction: What is rivaroxaban af-ter transcatheter aortic-valve replacement?

Output: Dabigatran Versus Warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rivaroxaban af-ter transcatheter aortic-valve replacement?. ### Response: Dabigatran Versus Warfarin.


Instruction: What is Edwards FH, Cohen DJ, O’Brien SM, et al. developing and validation of a risk prediction model for in-hospital mortality?

Output: transcatheter aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Edwards FH, Cohen DJ, O’Brien SM, et al. developing and validation of a risk prediction model for in-hospital mortality?. ### Response: transcatheter aortic valve replacement.


Instruction: What is the name of the registry model used to predict mortality after a transcatheter aortic valve replacement?

Output: Transcatheter Valve Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry model used to predict mortality after a transcatheter aortic valve replacement?. ### Response: Transcatheter Valve Therapy.


Instruction: What year was the JAMA Cardiol. 1:46–52?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the JAMA Cardiol. 1:46–52?. ### Response: 2016.


Instruction: How long does it take for a patient to die after a transcatheter aortic valve replacement?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a patient to die after a transcatheter aortic valve replacement?. ### Response: 1-year.


Instruction: What is the name of the new scoring system used in the TAVI risk scoring system?

Output: STS/ACC model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the new scoring system used in the TAVI risk scoring system?. ### Response: STS/ACC model.


Instruction: Who is the author of the study?

Output: Edwards FH, Cohen DJ, O’Brien SM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study?. ### Response: Edwards FH, Cohen DJ, O’Brien SM.


Instruction: What is a risk score to predict after transcatheter aortic valve replacement?

Output: new pacemaker implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk score to predict after transcatheter aortic valve replacement?. ### Response: new pacemaker implantation.


Instruction: What is the JACC Cardiovasc Interv 2019;12:2133-42?

Output: Development of a risk score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JACC Cardiovasc Interv 2019;12:2133-42?. ### Response: Development of a risk score.


Instruction: What is a risk prediction model for in-hospital stroke after transcatheter aortic valve replacement?

Output: Development and application of a risk prediction model for in-hospital stroke after transcatheter aortic valve replacement: a report from the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk prediction model for in-hospital stroke after transcatheter aortic valve replacement?. ### Response: Development and application of a risk prediction model for in-hospital stroke after transcatheter aortic valve replacement: a report from the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.


Instruction: What is the Society of Thoracic Surgeons/American College of Cardiology report on?

Output: Transcatheter Valve Therapy Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Society of Thoracic Surgeons/American College of Cardiology report on?. ### Response: Transcatheter Valve Therapy Registry.


Instruction: What is the impact of frailty on functional survival in patients 1 year after cardiac surgery?

Output: func-tional survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of frailty on functional survival in patients 1 year after cardiac surgery?. ### Response: func-tional survival.


Instruction: What was the J Thorac Cardiovasc Surg. 2017;154:1990–9?

Output: The impact of frailty on func-tional survival in patients 1 year after cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Thorac Cardiovasc Surg. 2017;154:1990–9?. ### Response: The impact of frailty on func-tional survival in patients 1 year after cardiac surgery.


Instruction: Afilalo J, Alexander KP, MackMJ, et al. Frailtiness assessment in the cardiovascular care of older adults.

Output: 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Afilalo J, Alexander KP, MackMJ, et al. Frailtiness assessment in the cardiovascular care of older adults.. ### Response: 8.


Instruction: J Am Coll Cardiol. 2014;63:747–62

Output: 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Am Coll Cardiol. 2014;63:747–62. ### Response: 8.


Instruction: What does J Am Coll Cardiol. 2014;63:747–62?

Output: Frailty assessment in the cardiovas-cular care of older adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does J Am Coll Cardiol. 2014;63:747–62?. ### Response: Frailty assessment in the cardiovas-cular care of older adults.


Instruction: What does Schoenenberger AW, Moser A, Bertschi D, et al. do?

Output: Improvement of risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Schoenenberger AW, Moser A, Bertschi D, et al. do?. ### Response: Improvement of risk.


Instruction: What is the name of the update to the heart failure guideline that includes topics where new evidence has been presented?

Output: 9.1 Introduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the update to the heart failure guideline that includes topics where new evidence has been presented?. ### Response: 9.1 Introduction.


Instruction: When was the heart failure guideline published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the heart failure guideline published?. ### Response: 2010.


Instruction: When was a review of new evidence carried out?

Output: after 20 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a review of new evidence carried out?. ### Response: after 20 10.


Instruction: What was done to determine if any changes to current recommendations were required?

Output: A review of new evidence published after 20 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was done to determine if any changes to current recommendations were required?. ### Response: A review of new evidence published after 20 10.


Instruction: When was the decision on which topics to include in the update of the guideline made?

Output: following consultation of the scope

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the decision on which topics to include in the update of the guideline made?. ### Response: following consultation of the scope.


Instruction: What is the section that includes multidisciplinary team working,transition and continuity between different heart failure care settings and information and support needs?

Output: update of the guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the section that includes multidisciplinary team working,transition and continuity between different heart failure care settings and information and support needs?. ### Response: update of the guideline.


Instruction: What topics were not included in the scope of the update?

Output: multidisciplinary team working,transition and continuity between different heart failure care settings  and information and support needs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What topics were not included in the scope of the update?. ### Response: multidisciplinary team working,transition and continuity between different heart failure care settings  and information and support needs.


Instruction: What is the guid eline for more information?

Output: Appendix R

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the guid eline for more information?. ### Response: Appendix R.


Instruction: What is NICE’s guideline on depression in adults with a chronic physical health problem 9.2 Team working in the management of heart failure 9.2.1 Introduction Heart failure is a complex disorder whose management involves what?

Output: a number of professional groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE’s guideline on depression in adults with a chronic physical health problem 9.2 Team working in the management of heart failure 9.2.1 Introduction Heart failure is a complex disorder whose management involves what?. ### Response: a number of professional groups.


Instruction: What is a complex disorder whose management involves a number of professional groups?

Output: Heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a complex disorder whose management involves a number of professional groups?. ### Response: Heart failure.


Instruction: What do members of different professional groups contribute to meet the complex needs of the patients?

Output: their experience and expertise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do members of different professional groups contribute to meet the complex needs of the patients?. ### Response: their experience and expertise.


Instruction: What does MDT stand for?

Output: multi -disciplinary team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MDT stand for?. ### Response: multi -disciplinary team.


Instruction: What is a well established team to support people with heart failure in the UK?

Output: Multidisciplinary teams

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a well established team to support people with heart failure in the UK?. ### Response: Multidisciplinary teams.


Instruction: What was the role of the MDT in the care of patients with heart failure care recognised in the NICE guidelines published in 2003?

Output: deliver optimal care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the role of the MDT in the care of patients with heart failure care recognised in the NICE guidelines published in 2003?. ### Response: deliver optimal care.


Instruction: What has accumulated that has investigated the composition, com petencies, needs for support, and the need for support?

Output: MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has accumulated that has investigated the composition, com petencies, needs for support, and the need for support?. ### Response: MDT.


Instruction: What were the competencies that should be present in a MDT to deliver optimal care for patients with heart failu re as care?

Output: Members of different professional groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the competencies that should be present in a MDT to deliver optimal care for patients with heart failu re as care?. ### Response: Members of different professional groups.


Instruction: What should be present in the multi disciplinary teams involved in outpatient or community based care of people with heart failure?

Output: competencies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be present in the multi disciplinary teams involved in outpatient or community based care of people with heart failure?. ### Response: competencies.


Instruction: What is the name of the document that describes the care of people with heart failure?

Output: NICE guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that describes the care of people with heart failure?. ### Response: NICE guidelines.


Instruction: What are the PICO characteristics of the review question?

Output: Table 97

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the PICO characteristics of the review question?. ### Response: Table 97.


Instruction: What is an example of a high risk patient?

Output:  new diagnosis   recent decompensation (defined as hospital admission due to HF)   severe and/or unresponsive disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a high risk patient?. ### Response:  new diagnosis   recent decompensation (defined as hospital admission due to HF)   severe and/or unresponsive disease.


Instruction: What is the term for a recent decompensation due to HF?

Output: hospital admission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for a recent decompensation due to HF?. ### Response: hospital admission.


Instruction: What is the name of the procedure used to treat infective endocarditis?

Output: Shelhigh stentless bioprosthesis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used to treat infective endocarditis?. ### Response: Shelhigh stentless bioprosthesis.


Instruction: How long was the single centre experience in a sub-group of 255 patients?

Output: seven-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the single centre experience in a sub-group of 255 patients?. ### Response: seven-year.


Instruction: What type of valves were implantation results after?

Output: mechanical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valves were implantation results after?. ### Response: mechanical.


Instruction: How many patients were treated with the Shelhigh stentless bioprosthesis?

Output: 255

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with the Shelhigh stentless bioprosthesis?. ### Response: 255.


Instruction: What is superiority of surgical valve replacement versus medical therapy only?

Output: Prosthetic valve endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is superiority of surgical valve replacement versus medical therapy only?. ### Response: Prosthetic valve endocarditis.


Instruction: What is the name of the study that examined the clinical presentation, etiology, and outcome of infective endocarditis in the 21st century?

Output: International Collaboration on Endocarditis-Prospective Cohort Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the clinical presentation, etiology, and outcome of infective endocarditis in the 21st century?. ### Response: International Collaboration on Endocarditis-Prospective Cohort Study.


Instruction: What was the name given to the study?

Output: International Collaboration on Endocarditis-Prospective Cohort Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name given to the study?. ### Response: International Collaboration on Endocarditis-Prospective Cohort Study.


Instruction: How long does it take to die from Staphylococcus aureus infective endocarditis?

Output: 6-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to die from Staphylococcus aureus infective endocarditis?. ### Response: 6-month.


Instruction: What is the name of the prospective cohort study that looked at the epidemiology and predictors of 6-month mortality?

Output: International Collaboration on Endocarditis-Prospective Cohort Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective cohort study that looked at the epidemiology and predictors of 6-month mortality?. ### Response: International Collaboration on Endocarditis-Prospective Cohort Study.


Instruction: What predictors of 6-month mortality: a prospective cohort study?

Output: Infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predictors of 6-month mortality: a prospective cohort study?. ### Response: Infective endocarditis.


Instruction: What is a propensity score analysis in patients with infective endocarditis?

Output: Early surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a propensity score analysis in patients with infective endocarditis?. ### Response: Early surgery.


Instruction: When did Ellis ME, Al-Abdely H, Sandridge A, et al. find evidence in the literature?

Output: 1965–1995

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ellis ME, Al-Abdely H, Sandridge A, et al. find evidence in the literature?. ### Response: 1965–1995.


Instruction: How many cases of prosthetic valve endocarditis were there in the ICU?

Output: 122

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of prosthetic valve endocarditis were there in the ICU?. ### Response: 122.


Instruction: What is the name of the disease that has been documented in the world literature from 1965 to 1995?

Output: Fungal endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that has been documented in the world literature from 1965 to 1995?. ### Response: Fungal endocarditis.


Instruction: How many cases of Staphylococcus aureus prosthetic valve infective endocarditis are there?

Output: 61

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of Staphylococcus aureus prosthetic valve infective endocarditis are there?. ### Response: 61.


Instruction: What is the name of the merged database used to determine the prognostic factors in 61 cases?

Output: International Collaboration on Endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the merged database used to determine the prognostic factors in 61 cases?. ### Response: International Collaboration on Endocarditis.


Instruction: When did Clin Infect Dis. 2004:38:1323–7?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Clin Infect Dis. 2004:38:1323–7?. ### Response: 2004.


Instruction: How long did Melgar GR, Nasser RM, Gordon SM, et al. have experience in a tertiary care hospital?

Output: 11-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did Melgar GR, Nasser RM, Gordon SM, et al. have experience in a tertiary care hospital?. ### Response: 11-year.


Instruction: What is a consequence of medical progress in Staphylococcus aureus endocarditis?

Output: death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a consequence of medical progress in Staphylococcus aureus endocarditis?. ### Response: death.


Instruction: How many episodes of Staphylococcus aureus native valve infective endocarditis were from the Interna-tional Collaboration on Endocardiotis Merged Database?

Output: 566

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many episodes of Staphylococcus aureus native valve infective endocarditis were from the Interna-tional Collaboration on Endocardiotis Merged Database?. ### Response: 566.


Instruction: What is a consequence of medical progress?

Output: aphylococcus aureus endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a consequence of medical progress?. ### Response: aphylococcus aureus endocarditis.


Instruction: How many patients with prosthetic valve endocarditis need surgery?

Output: all

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with prosthetic valve endocarditis need surgery?. ### Response: all.


Instruction: What is the name of the disease caused by Staphylococcus aureus?

Output: infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease caused by Staphylococcus aureus?. ### Response: infective endocarditis.


Instruction: What is the acronym for the Acute Decompensated Heart Failure National Registry?

Output: ADHERE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Acute Decompensated Heart Failure National Registry?. ### Response: ADHERE.


Instruction: How many patients were hospitalized for heart failure in the United States?

Output: 100,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were hospitalized for heart failure in the United States?. ### Response: 100,000.


Instruction: What is ADHERE?

Output: Acute Decompensated Heart Failure National Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ADHERE?. ### Response: Acute Decompensated Heart Failure National Registry.


Instruction: What are the primary results of the Registry to Improve the Use of Evidence-Based Heart Failure?

Output: Improving evidence-based care for heart fail-ure in outpatient cardiology practices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the primary results of the Registry to Improve the Use of Evidence-Based Heart Failure?. ### Response: Improving evidence-based care for heart fail-ure in outpatient cardiology practices.


Instruction: What is the acronym for the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting?

Output: IMPROVE HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting?. ### Response: IMPROVE HF.


Instruction: What does IMPROVE HF stand for?

Output: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does IMPROVE HF stand for?. ### Response: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting.


Instruction: When was the Circulation.122:585-596 published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.122:585-596 published?. ### Response: 2010.


Instruction: What is the difference between coro-nary artery bypass grafting and medical therapy?

Output: long-term

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between coro-nary artery bypass grafting and medical therapy?. ### Response: long-term.


Instruction: When was this article published?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: May 3, 2023.


Instruction: What if the onset of t he arrh ythmia is less than 48 hours?

Output: offer eit her rat e or rh ythm contr ol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What if the onset of t he arrh ythmia is less than 48 hours?. ### Response: offer eit her rat e or rh ythm contr ol.


Instruction: What offer if onset is mor e than 48 hrs or is uncertain?

Output: rat e contr ol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What offer if onset is mor e than 48 hrs or is uncertain?. ### Response: rat e contr ol.


Instruction: What do people with atrial fibrillation suspect ed concomitant acut e decompensation hear t failure seek senior specialist input on?

Output: use of beta-block ers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do people with atrial fibrillation suspect ed concomitant acut e decompensation hear t failure seek senior specialist input on?. ### Response: use of beta-block ers.


Instruction: What does not use calcium-channel block ers?

Output: In people wit h atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not use calcium-channel block ers?. ### Response: In people wit h atrial fibrillation.


Instruction: What do not use calcium-channel blockers?

Output: In people wit h atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do not use calcium-channel blockers?. ### Response: In people wit h atrial fibrillation.


Instruction: What should be considered in people with new-onset atrial fibrillation who will be tr eated?

Output: pharmacological or electrical car dioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered in people with new-onset atrial fibrillation who will be tr eated?. ### Response: pharmacological or electrical car dioversion.


Instruction: What is a rh ythm-contr ol strat egy?

Output: new-onset atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a rh ythm-contr ol strat egy?. ### Response: new-onset atrial fibrillation.


Instruction: 1.8.5 If pharmacological car dioversion has been agr eed on clinical and resour ce gr ounds f or new-onset atrial fibrillation, off er?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1.8.5 If pharmacological car dioversion has been agr eed on clinical and resour ce gr ounds f or new-onset atrial fibrillation, off er?. ### Response: •.


Instruction: What type of hear t disease do people wit h evidence of?

Output: structural

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hear t disease do people wit h evidence of?. ### Response: structural.


Instruction: What is the duration of t he arrh ythmia greater than 48 hours in people with atrial fibrillation?

Output: 1.8.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the duration of t he arrh ythmia greater than 48 hours in people with atrial fibrillation?. ### Response: 1.8.6.


Instruction: What is the duration of t he arrh ythmia?

Output: greater than 48  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the duration of t he arrh ythmia?. ### Response: greater than 48  hours.


Instruction: What is considered for long-t erm rhythmic control, dela y car dioversion?

Output: clinical cir cumstances

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered for long-t erm rhythmic control, dela y car dioversion?. ### Response: clinical cir cumstances.


Instruction: How long is the minimum period of therapeutic anticoagulation?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the minimum period of therapeutic anticoagulation?. ### Response: 3.


Instruction: How long is a minimum of 3 weeks?

Output: until t hey have been maintained on therapeutic anticoagulation f

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is a minimum of 3 weeks?. ### Response: until t hey have been maintained on therapeutic anticoagulation f.


Instruction: What do you offer during t his period?

Output: rat e contr ol as appr opriat e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do you offer during t his period?. ### Response: rat e contr ol as appr opriat e.


Instruction: Do not off er magnesium or a calcium-channel block er for what?

Output: pharmacological car dioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do not off er magnesium or a calcium-channel block er for what?. ### Response: pharmacological car dioversion.


Instruction: What is t he rationale and impact section on rat e and rh ythm contr ol for people pr esenting acut ely?

Output: seek senior specialist input on t he use of beta-block ers and do not use calcium-channel block ers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he rationale and impact section on rat e and rh ythm contr ol for people pr esenting acut ely?. ### Response: seek senior specialist input on t he use of beta-block ers and do not use calcium-channel block ers.


Instruction: Atrial fibrillation: diagnosis and management (NG196) NICE 2022.

Output: All right s reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation: diagnosis and management (NG196) NICE 2022.. ### Response: All right s reserved.


Instruction: All right s reserved.

Output: Atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: All right s reserved.. ### Response: Atrial fibrillation.


Instruction: What is the last updat ed 30 June 2021?

Output: Page 21of 47

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 30 June 2021?. ### Response: Page 21of 47.


Instruction: How many subjects were randomized to percutaneous LAA closure with the WATCHMAN device?

Output: 707

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many subjects were randomized to percutaneous LAA closure with the WATCHMAN device?. ### Response: 707.


Instruction: How long after device placement were patients treated with warfarin?

Output: 45 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after device placement were patients treated with warfarin?. ### Response: 45 days.


Instruction: What did patients receive after aspirin plus clopidogrel from echocardiographically demon-strated closure?

Output: aspirin alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients receive after aspirin plus clopidogrel from echocardiographically demon-strated closure?. ### Response: aspirin alone.


Instruction: What was LAA closure noninferior to warfarin for preventing the primary outcome of ischemic or hemorrhagic stroke?

Output: mean 18-month follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was LAA closure noninferior to warfarin for preventing the primary outcome of ischemic or hemorrhagic stroke?. ### Response: mean 18-month follow-up.


Instruction: What was the mean 18-month follow-up?

Output: (RR, 0.62

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean 18-month follow-up?. ### Response: (RR, 0.62.


Instruction: What was less frequent in the LAA closure group?

Output: Hemorrhagic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was less frequent in the LAA closure group?. ### Response: Hemorrhagic stroke.


Instruction: Why was ischemic stroke insignificantly more frequent?

Output: procedure-related strokes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was ischemic stroke insignificantly more frequent?. ### Response: procedure-related strokes.


Instruction: How many patients had procedure-related strokes?

Output: 5 of the 449

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had procedure-related strokes?. ### Response: 5 of the 449.


Instruction: How many of the 449 patients in which LAA closure was attempted had long-term residual deficit?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the 449 patients in which LAA closure was attempted had long-term residual deficit?. ### Response: 2.


Instruction: At 1588 patient-years of follow-up, the rate of the primary efficacy end point of stroke was not inferior for what device?

Output: WATCHMAN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At 1588 patient-years of follow-up, the rate of the primary efficacy end point of stroke was not inferior for what device?. ### Response: WATCHMAN.


Instruction: What was not inferior for the WATCHMAN device compared with warfarin?

Output: the rate of the primary efficacy end point of stroke, systemic embolism, and cardiovascular death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not inferior for the WATCHMAN device compared with warfarin?. ### Response: the rate of the primary efficacy end point of stroke, systemic embolism, and cardiovascular death.


Instruction: What are substantial reasons for proceeding cautiously with this approach?

Output: Although this approach appears promising

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are substantial reasons for proceeding cautiously with this approach?. ### Response: Although this approach appears promising.


Instruction: What were the severe adverse events associated with moxonidine in this RCT?

Output: gastrointestinal symptoms, dizziness, headache andtiredness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the severe adverse events associated with moxonidine in this RCT?. ### Response: gastrointestinal symptoms, dizziness, headache andtiredness.


Instruction: What percentage of patients receiving moxonedine had gastrointestinal symptoms, dizziness, headache andtireness?

Output: between 10 to 15%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients receiving moxonedine had gastrointestinal symptoms, dizziness, headache andtireness?. ### Response: between 10 to 15%.


Instruction: Why are alpha-agonists valuable as adjunctivetherapy for high BP in CKD?

Output: Sincealpha-agonists do not interact with other commonly usedantihypertensive agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are alpha-agonists valuable as adjunctivetherapy for high BP in CKD?. ### Response: Sincealpha-agonists do not interact with other commonly usedantihypertensive agents.


Instruction: What are alpha-agonists useful for in CKD patients already taking?

Output: high BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are alpha-agonists useful for in CKD patients already taking?. ### Response: high BP.


Instruction: What is caution advised when using alpha agonists in the elderly?

Output: side-effectproﬁle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is caution advised when using alpha agonists in the elderly?. ### Response: side-effectproﬁle.


Instruction: In a large study, what was high-dose moxonidine used for?

Output: creased mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a large study, what was high-dose moxonidine used for?. ### Response: creased mortality.


Instruction: What was associated with increased mortality in non-CKD patients?

Output: high-dose moxonidine use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with increased mortality in non-CKD patients?. ### Response: high-dose moxonidine use.


Instruction: What is probably wise if overt heart failure is present?

Output: Avoidance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is probably wise if overt heart failure is present?. ### Response: Avoidance.


Instruction: Clonidine can slow what?

Output: pulse rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Clonidine can slow what?. ### Response: pulse rate.


Instruction: What is avoided if bradycardia or heart block is present?

Output: clonidine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is avoided if bradycardia or heart block is present?. ### Response: clonidine.


Instruction: Combination of alpha-agonists with other antihyperten-s i v ed to reduce vasodilatation-induced fluid retention.

Output: similar side effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Combination of alpha-agonists with other antihyperten-s i v ed to reduce vasodilatation-induced fluid retention.. ### Response: similar side effects.


Instruction: What is vasodilatation-induced fluid retention?

Output: smooth-muscle relaxation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is vasodilatation-induced fluid retention?. ### Response: smooth-muscle relaxation.


Instruction: Combination with other antihyperten-s i v ed r u g si su s ua l l what?

Output: yt r

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Combination with other antihyperten-s i v ed r u g si su s ua l l what?. ### Response: yt r.


Instruction: What do alpha-agonists and CNIs or mTOR inhibitors not have in common?

Output: Interactions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do alpha-agonists and CNIs or mTOR inhibitors not have in common?. ### Response: Interactions.


Instruction: What do beta-adrenergic blockers selectively act to reduce by causing peripheral vasodilatation?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do beta-adrenergic blockers selectively act to reduce by causing peripheral vasodilatation?. ### Response: BP.


Instruction: Prazosin, doxazosine, andterazosn are the most commonly used in what type of hypertension?

Output: alpha-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prazosin, doxazosine, andterazosn are the most commonly used in what type of hypertension?. ### Response: alpha-blockers.


Instruction: What is the most commonly used intreatment of hypertension?

Output: alpha-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most commonly used intreatment of hypertension?. ### Response: alpha-blockers.


Instruction: What is an adjunctivetreatment for elevated BP in CKD patients?

Output: Alpha-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an adjunctivetreatment for elevated BP in CKD patients?. ### Response: Alpha-blockers.


Instruction: What does not require dose modification in cases of kidney failure?

Output: Alpha-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not require dose modification in cases of kidney failure?. ### Response: Alpha-blockers.


Instruction: Where are alpha-blockers excreted?

Output: via the liver

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are alpha-blockers excreted?. ### Response: via the liver.


Instruction: What reduces thesymptoms of benign prostatic hyperplasia?

Output: Alpha-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduces thesymptoms of benign prostatic hyperplasia?. ### Response: Alpha-blockers.


Instruction: What are the common side effects of beta-blockers?

Output: postural hypotension,tachycardia and headache

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the common side effects of beta-blockers?. ### Response: postural hypotension,tachycardia and headache.


Instruction: What should be commenced at low dosage to avoid a first-dose hypotensive reaction?

Output: Alpha-blockers donot require dose modi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be commenced at low dosage to avoid a first-dose hypotensive reaction?. ### Response: Alpha-blockers donot require dose modi.


Instruction: There are few data available about what?

Output: alpha-blocker combinations with other BP lowering drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are few data available about what?. ### Response: alpha-blocker combinations with other BP lowering drugs.


Instruction: What can lead to peripheral edema?

Output: Vasodilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can lead to peripheral edema?. ### Response: Vasodilatation.


Instruction: What are diuretics commonly combined with?

Output: alpha-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are diuretics commonly combined with?. ### Response: alpha-blockers.


Instruction: The effectiveness of this maneuver has not been studied what?

Output: Vasodilatation can lead to peripheral edema, so diuretics arecommonly combined with alpha-blockers, although theefﬁcacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The effectiveness of this maneuver has not been studied what?. ### Response: Vasodilatation can lead to peripheral edema, so diuretics arecommonly combined with alpha-blockers, although theefﬁcacy.


Instruction: What does vasodilatation do?

Output: lead to peripheral edema

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does vasodilatation do?. ### Response: lead to peripheral edema.


Instruction: What has been no significant change to our understanding?

Output: alpha-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been no significant change to our understanding?. ### Response: alpha-blockers.


Instruction: What does ACTION Registry-GWTG stand for?

Output: Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACTION Registry-GWTG stand for?. ### Response: Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines.


Instruction: What is the acronym for the Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines?

Output: GWTG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines?. ### Response: GWTG.


Instruction: When did JACC Cardiovasc Interv. 2010:3:419–27?

Output: 422

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JACC Cardiovasc Interv. 2010:3:419–27?. ### Response: 422.


Instruction: What is the acronym for the Global Registry of Acute Coronary Events?

Output: GRACE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Global Registry of Acute Coronary Events?. ### Response: GRACE.


Instruction: What does GRACE stand for?

Output: Global Registry of Acute Coronary Events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GRACE stand for?. ### Response: Global Registry of Acute Coronary Events.


Instruction: What is clopidogrel used for in patients with non-ST-segment elevation acute coronary syn-dromes undergoing?

Output: coronary artery bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel used for in patients with non-ST-segment elevation acute coronary syn-dromes undergoing?. ### Response: coronary artery bypass surgery.


Instruction: What is the J Am Coll Cardiol. 2006;48:281–6. 424?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2006;48:281–6. 424?. ### Response: clopidogrel.


Instruction: What is the CURE Trial?

Output: Clopidogrel in Unstable angina to prevent Recurrent ischemic Events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CURE Trial?. ### Response: Clopidogrel in Unstable angina to prevent Recurrent ischemic Events.


Instruction: What is clopidogrel used for after coronary artery bypass graft surgery?

Output: bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel used for after coronary artery bypass graft surgery?. ### Response: bleeding.


Instruction: After coronary artery bypass graft surgery?

Output: Clopidogrel use and bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After coronary artery bypass graft surgery?. ### Response: Clopidogrel use and bleeding.


Instruction: What is the name of the ACUITY trial?

Output: Acute Catheterization and Urgent Intervention Triage strategY

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACUITY trial?. ### Response: Acute Catheterization and Urgent Intervention Triage strategY.


Instruction: What is a simplified approach to the diagnosis of coronary stenosis?

Output: management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simplified approach to the diagnosis of coronary stenosis?. ### Response: management.


Instruction: What is the effect of combination evidence-based medical therapy on mortality?

Output: Impact of combination evidence-based medical therapy on mortality in patients with acute coronary syn-dromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of combination evidence-based medical therapy on mortality?. ### Response: Impact of combination evidence-based medical therapy on mortality in patients with acute coronary syn-dromes.


Instruction: What is a simplified approach to the management of non-ST-segment elevation acute coronary syn-dromes?

Output: Gluckman TJ, Sachdev M, Schulman SP, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simplified approach to the management of non-ST-segment elevation acute coronary syn-dromes?. ### Response: Gluckman TJ, Sachdev M, Schulman SP, et al.


Instruction: When did JAMA issue 293:349–57?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 293:349–57?. ### Response: 2005.


Instruction: What did Dracup K, Alonzo AA, Atkins JM, et al. recommend from the National Heart Attack Association?

Output: role in mini-mizing prehospital delay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Dracup K, Alonzo AA, Atkins JM, et al. recommend from the National Heart Attack Association?. ### Response: role in mini-mizing prehospital delay.


Instruction: What is the National Heart Attack Alert Program's recommendation for?

Output: prehospital delay in patients at high risk for acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the National Heart Attack Alert Program's recommendation for?. ### Response: prehospital delay in patients at high risk for acute myocardial infarction.


Instruction: What does the Working Group on Educational Strategies To Prevent Prehospital Delay in Patients at High Risk for Acute Myocardial Infarction do?

Output: mini-mizing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Working Group on Educational Strategies To Prevent Prehospital Delay in Patients at High Risk for Acute Myocardial Infarction do?. ### Response: mini-mizing.


Instruction: What is the ACCF/ACG/AHA 2010 expert consensus document on?

Output: the concomitant use of proton pump inhibitors and thienopyridines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACCF/ACG/AHA 2010 expert consensus document on?. ### Response: the concomitant use of proton pump inhibitors and thienopyridines.


Instruction: What is a focused update of?

Output: ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a focused update of?. ### Response: ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use.


Instruction: Who wrote a report on reducing the gastrointestinal risks of antiplatelet therapy?

Output: ACCF/ACG/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote a report on reducing the gastrointestinal risks of antiplatelet therapy?. ### Response: ACCF/ACG/AHA.


Instruction: What did the American College of Cardiology Foundation Task Force on Expert Consensus Documents do?

Output: reducing the gastrointestinal risks of antiplatelet therapy and NSAID use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology Foundation Task Force on Expert Consensus Documents do?. ### Response: reducing the gastrointestinal risks of antiplatelet therapy and NSAID use.


Instruction: What was the name of the Task Force?

Output: American College of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the Task Force?. ### Response: American College of Cardiology Foundation.


Instruction: When was the Circulation.122:2619–633.

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.122:2619–633.. ### Response: 2010.


Instruction: What drug did Bhatt DL, Cryer BL, Contant CF, et al. use with or without omeprazole in coronary artery disease?

Output: Clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug did Bhatt DL, Cryer BL, Contant CF, et al. use with or without omeprazole in coronary artery disease?. ### Response: Clopidogrel.


Instruction: What does Dans AL, Connolly SJ, Wallentin L, et al. believe to be a concomitant use of antiplatelet?

Output: proton pump inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Dans AL, Connolly SJ, Wallentin L, et al. believe to be a concomitant use of antiplatelet?. ### Response: proton pump inhibitors.


Instruction: What is the e574S Antithrombotic Therapy for Atrial Fibrillation?

Output: patients before nonanticoagulated cardioversion from atrial ﬁ  brillation and ﬂ  utter: an analysis of pooled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the e574S Antithrombotic Therapy for Atrial Fibrillation?. ### Response: patients before nonanticoagulated cardioversion from atrial ﬁ  brillation and ﬂ  utter: an analysis of pooled trials.


Instruction: What is an analysis of pooled trials?

Output: e574S Antithrombotic Therapy for Atrial Fibrillationof patients before nonanticoagulated cardioversion from atrial ﬁ  brillation and ﬂ  utter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an analysis of pooled trials?. ### Response: e574S Antithrombotic Therapy for Atrial Fibrillationof patients before nonanticoagulated cardioversion from atrial ﬁ  brillation and ﬂ  utter.


Instruction: How many ( 1 ): 71-75?

Output: 129

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 1 ): 71-75?. ### Response: 129.


Instruction: What are the embolic complications of direct current cardioversion of atrial arrhythmias?

Output: association with low intensity of anticoagula-tion at the time of cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the embolic complications of direct current cardioversion of atrial arrhythmias?. ### Response: association with low intensity of anticoagula-tion at the time of cardioversion.


Instruction: What is associated with low intensity of anticoagula-tion at the heart?

Output: Embolic complications of direct current cardioversion of atrial arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with low intensity of anticoagula-tion at the heart?. ### Response: Embolic complications of direct current cardioversion of atrial arrhythmias.


Instruction: Atrial arrhythmias are associated with low intensity of what at the time of cardioversion?

Output: anticoagula-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial arrhythmias are associated with low intensity of what at the time of cardioversion?. ### Response: anticoagula-tion.


Instruction: J Am Coll Cardiol. 2002; 40 ( 5 ): 926-933.

Output: time of cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Am Coll Cardiol. 2002; 40 ( 5 ): 926-933.. ### Response: time of cardioversion.


Instruction: What is the name of the retrospective study of electrical cardioversion of atrial fi brillation or fl utter?

Output: bril-lation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the retrospective study of electrical cardioversion of atrial fi brillation or fl utter?. ### Response: bril-lation.


Instruction: What is Manning's name?

Output: WJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Manning's name?. ### Response: WJ.


Instruction: What type of evaluation of atrial mechanical function after elec-trical cardioversion?

Output: Pulsed Doppler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of evaluation of atrial mechanical function after elec-trical cardioversion?. ### Response: Pulsed Doppler.


Instruction: After elec-trical cardioversion of atrial fibrillation, what is the name of the procedure?

Output: transoesophageal echocardiog-raphy-guided cardioversion: Assessment of Cardioversion Using Transoesophageal Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After elec-trical cardioversion of atrial fibrillation, what is the name of the procedure?. ### Response: transoesophageal echocardiog-raphy-guided cardioversion: Assessment of Cardioversion Using Transoesophageal Echocardiography.


Instruction: When was the J Am Coll Cardiol 13 ( 3 ): 617 - 623 published?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 13 ( 3 ): 617 - 623 published?. ### Response: 1989.


Instruction: What is the difference between Dabigatran and warfarin in patients with atrial fibrillation?

Output: enoxaparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between Dabigatran and warfarin in patients with atrial fibrillation?. ### Response: enoxaparin.


Instruction: What is a comparison of DaBigatran versus Warfarin?

Output: an anal-ysis of patients undergoing cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison of DaBigatran versus Warfarin?. ### Response: an anal-ysis of patients undergoing cardioversion.


Instruction: How many patients had atrial fibrillation in 2011?

Output: 131 - 136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had atrial fibrillation in 2011?. ### Response: 131 - 136.


Instruction: What year did 123 ( 2 ): 131 - 136 occur?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did 123 ( 2 ): 131 - 136 occur?. ### Response: 2011.


Instruction: What was the average number of deaths in 2011?

Output: 131 - 136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the average number of deaths in 2011?. ### Response: 131 - 136.


Instruction: What does transesophageal echocardiography exclude the presence of?

Output: atrial thrombi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does transesophageal echocardiography exclude the presence of?. ### Response: atrial thrombi.


Instruction: How many ( 11): 750 - 755 are in 1993?

Output: 328

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 11): 750 - 755 are in 1993?. ### Response: 328.


Instruction: How many ( 11 ): 750 - 755?

Output: 328

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 11 ): 750 - 755?. ### Response: 328.


Instruction: Klein AL, Grimm RA, Murray RD, et al ; Assessment of Cardioversion Using Transesophageal Echocardiography Investigators?

Output: Klein   AL ,  Grimm   RA ,  Murray   RD ,  et al ;  Assessment of Cardioversion Using Transesophageal Echocardiography Investigators .  Use of transesophageal echocardiography to guide cardioversion in patients with atrial ﬁ  brillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Klein AL, Grimm RA, Murray RD, et al ; Assessment of Cardioversion Using Transesophageal Echocardiography Investigators?. ### Response: Klein   AL ,  Grimm   RA ,  Murray   RD ,  et al ;  Assessment of Cardioversion Using Transesophageal Echocardiography Investigators .  Use of transesophageal echocardiography to guide cardioversion in patients with atrial ﬁ  brillation.


Instruction: What is the use of transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation?

Output: Assessment of Cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use of transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation?. ### Response: Assessment of Cardioversion.


Instruction: How many ( 19): 1411-1420 were in 2001?

Output: 344

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 19): 1411-1420 were in 2001?. ### Response: 344.


Instruction: What is the acronym for Assessment of Cardioversion Using Transesophageal Echocardiography?

Output: ACUTE) II Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Assessment of Cardioversion Using Transesophageal Echocardiography?. ### Response: ACUTE) II Investigators.


Instruction: What are anticoagulant and anti-influent used for?

Output: ammatory responses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are anticoagulant and anti-influent used for?. ### Response: ammatory responses.


Instruction: What is the name of the group that investigated anticoagulant and anti-infl ammatory responses using enoxaparin versus unfractionated heparin for transesophageal echocardiogra-phy-guided cardioversion of atrial fibrillation?

Output: ACUTE II Steering and Publications Committee for the ACUTE II Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that investigated anticoagulant and anti-infl ammatory responses using enoxaparin versus unfractionated heparin for transesophageal echocardiogra-phy-guided cardioversion of atrial fibrillation?. ### Response: ACUTE II Steering and Publications Committee for the ACUTE II Investigators.


Instruction: What is the name of the Steering and Publications Committee for the ACUTE II Investigators?

Output: ACUTE II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Steering and Publications Committee for the ACUTE II Investigators?. ### Response: ACUTE II.


Instruction: What is the name of the randomized multicentre study that compares enoxaparin and unfractionated heparin for short-term antithrombotic therapy in atrial fibril-lation patients?

Output: ACUTE) II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized multicentre study that compares enoxaparin and unfractionated heparin for short-term antithrombotic therapy in atrial fibril-lation patients?. ### Response: ACUTE) II.


Instruction: What is the name of the randomized multicentre study?

Output: ACUTE) II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized multicentre study?. ### Response: ACUTE) II.


Instruction: When did Eur Heart J issue 27 (23): 2858-2865?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J issue 27 (23): 2858-2865?. ### Response: 2006.


Instruction: M, De Luca L, Colonna P, Del Salvatore B,

Output: Sorino

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: M, De Luca L, Colonna P, Del Salvatore B,. ### Response: Sorino.


Instruction: What did Jneid and al 2017 AHA/ACC STEMI/NSTEMI Measure Set?

Output: American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Jneid and al 2017 AHA/ACC STEMI/NSTEMI Measure Set?. ### Response: American Heart Association Task Force on Practice Guidelines.


Instruction: What was the Task Force on Practice Guidelines?

Output: Writing Group to Develop the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Task Force on Practice Guidelines?. ### Response: Writing Group to Develop the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina.


Instruction: Who developed the Guidelines for the Management of Patients With Unstable Angina/NonST-Elevation Myocardial Infarction?

Output: American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed the Guidelines for the Management of Patients With Unstable Angina/NonST-Elevation Myocardial Infarction?. ### Response: American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons.


Instruction: What is the acronym for the American College of Emergency Physicians?

Output: AHA/ACC STEMI/NSTEMI Measure SetAmerican Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Emergency Physicians?. ### Response: AHA/ACC STEMI/NSTEMI Measure SetAmerican Heart Association Task Force on Practice Guidelines.


Instruction: What are the acronyms for the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons in 2007?

Output: AHA/ACC STEMI/NSTEMI Measure SetAmerican Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the acronyms for the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons in 2007?. ### Response: AHA/ACC STEMI/NSTEMI Measure SetAmerican Heart Association Task Force on Practice Guidelines.


Instruction: When was the ACC/AHA 2002 guidelines for the management of patients with chronic stable angina published?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ACC/AHA 2002 guidelines for the management of patients with chronic stable angina published?. ### Response: 2007.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?

Output: Writing Group to Develop the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?. ### Response: Writing Group to Develop the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina.


Instruction: What was the focus of the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina?

Output: chronic angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina?. ### Response: chronic angina.


Instruction: What is Chronic Stable Angina?

Output: management of patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chronic Stable Angina?. ### Response: management of patients.


Instruction: When was the Circulation 116:2762–72 published?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation 116:2762–72 published?. ### Response: 2007.


Instruction: What is the name of the Task Force to Update the 2001 Guidelines for the Evaluation of Heart Failure?

Output: Writing Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force to Update the 2001 Guidelines for the Evaluation of Heart Failure?. ### Response: Writing Committee.


Instruction: What is the name of the Working Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure?

Output: Writing Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Working Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure?. ### Response: Writing Committee.


Instruction: What year did the writing committee update the 2001 guidelines for the evaluation and management of heart failure?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the writing committee update the 2001 guidelines for the evaluation and management of heart failure?. ### Response: 2005.


Instruction: What was the focus of the 2007 focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the 2007 focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction?

Output: double-blind, randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction?. ### Response: double-blind, randomised controlled trial.


Instruction: What is the name of the double-blind, randomised controlled trial?

Output: Prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the double-blind, randomised controlled trial?. ### Response: Prasugrel.


Instruction: Prasugrel versus clopi-dogrel in patients with acute coronary syndromes?

Output: opidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prasugrel versus clopi-dogrel in patients with acute coronary syndromes?. ### Response: opidogrel.


Instruction: When did N Engl J Med. 2007:357:2001–15.

Output: 117

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med. 2007:357:2001–15.. ### Response: 117.


Instruction: What is the difference between clopidogrel and ticagrelor?

Output: Prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between clopidogrel and ticagrelor?. ### Response: Prasugrel.


Instruction: What is the acronym for Platelet Inhibition and Patient Outcomes (PLATO) trial?

Output: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Platelet Inhibition and Patient Outcomes (PLATO) trial?. ### Response: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis.


Instruction: When was the PLATO trial published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the PLATO trial published?. ### Response: 2010.


Instruction: What is clopidogrel compared to in patients with acute coronary syndromes?

Output: Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for re-perfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis. Circulation. 2010;122:2131–41. 118. James SK, Storey RF, Khurmi NS, et al. Ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel compared to in patients with acute coronary syndromes?. ### Response: Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for re-perfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis. Circulation. 2010;122:2131–41. 118. James SK, Storey RF, Khurmi NS, et al. Ticagrelor.


Instruction: What year did Circulation125:2914–21.

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circulation125:2914–21.. ### Response: 2012.


Instruction: What is the outcome of multivessel coronary intervention in the contemporary percutaneous revasculariza-tion era?

Output: 119

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the outcome of multivessel coronary intervention in the contemporary percutaneous revasculariza-tion era?. ### Response: 119.


Instruction: What year was Am J Cardiol 97:1585–90?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Am J Cardiol 97:1585–90?. ### Response: 2006.


Instruction: What is the name of the UKPDS group?

Output: UK Prospective Diabetes Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the UKPDS group?. ### Response: UK Prospective Diabetes Study.


Instruction: When did the UK Prospective Diabetes Study Group publish their findings?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the UK Prospective Diabetes Study Group publish their findings?. ### Response: 1998.


Instruction: What is a risk factor of complications in veterans with type 2 diabetes?

Output: Intensive blood-glucose control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor of complications in veterans with type 2 diabetes?. ### Response: Intensive blood-glucose control.


Instruction: What is the name of the meta-analysis of randomised controlled trials of intensive glucose control in patients with diabetes mellitus?

Output: S4.2-27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of randomised controlled trials of intensive glucose control in patients with diabetes mellitus?. ### Response: S4.2-27.


Instruction: What type of diabetes is veterans with?

Output: type 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes is veterans with?. ### Response: type 2.


Instruction: What is diabetes mellitus: a meta-analysis of randomised controlled trials?

Output: Effect of intensive control of glucose on cardiovascular outcomes and death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is diabetes mellitus: a meta-analysis of randomised controlled trials?. ### Response: Effect of intensive control of glucose on cardiovascular outcomes and death.


Instruction: What was the name of the systematic review and meta-analyse of car -diovascular outcome trials in 2018.

Output: SGLT2 inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic review and meta-analyse of car -diovascular outcome trials in 2018.. ### Response: SGLT2 inhibitors.


Instruction: What is SGLT2 inhibitors for?

Output: primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SGLT2 inhibitors for?. ### Response: primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes.