Instruction: What is the STS/ACC TVT registry used for?

Output: Procedural experience for transcath-eter aortic valve replacement and relation to outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the STS/ACC TVT registry used for?. ### Response: Procedural experience for transcath-eter aortic valve replacement and relation to outcomes.


Instruction: What are the out-comes of transcatheter aortic-valve replacement?

Output: Inclusion of functional status mea-sures in the risk adjustment of 30-day mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the out-comes of transcatheter aortic-valve replacement?. ### Response: Inclusion of functional status mea-sures in the risk adjustment of 30-day mortality.


Instruction: What is the name of the registry that provides insights into TAVR case volume?

Output: American College of Cardiology TVT Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry that provides insights into TAVR case volume?. ### Response: American College of Cardiology TVT Registry.


Instruction: What are the names of the patients with balloon-expandable prostheses?

Output: 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the patients with balloon-expandable prostheses?. ### Response: 23.


Instruction: What year did the JH y p e r te n s publish?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the JH y p e r te n s publish?. ### Response: 2003.


Instruction: What is the name of the fourth working party of the British Hypertension Society?

Output: 2004-BHS IV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the fourth working party of the British Hypertension Society?. ### Response: 2004-BHS IV.


Instruction: What is Hypertens 2004?

Output: J Hum

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Hypertens 2004?. ### Response: J Hum.


Instruction: What is Raskin P's profession?

Output: diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Raskin P's profession?. ### Response: diabetes.


Instruction: How is hypertension treated in adults with diabetes?

Output: Arauz-Pacheco C, Parrott MA, Raskin P. Treatment of hypertension in adultswith diabetes. Diabetes Care 2003; 26(Suppl 1): S80– S82.246. American Diabetes Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is hypertension treated in adults with diabetes?. ### Response: Arauz-Pacheco C, Parrott MA, Raskin P. Treatment of hypertension in adultswith diabetes. Diabetes Care 2003; 26(Suppl 1): S80– S82.246. American Diabetes Association.


Instruction: Who is the American Diabetes Association?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the American Diabetes Association?. ### Response: American Heart Association.


Instruction: What is a primary prevention of cardiovasculardiseases in people with diabetes mellitus?

Output: a scientiﬁc statement from theAmerican Heart Association and the American Diabetes Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a primary prevention of cardiovasculardiseases in people with diabetes mellitus?. ### Response: a scientiﬁc statement from theAmerican Heart Association and the American Diabetes Association.


Instruction: When was Circulation 2007; 115: 114–126?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation 2007; 115: 114–126?. ### Response: 2007.


Instruction: How long aft er sympt om onset can t he benefit s in r educed mor tality and improved functional out come w ere largely driv en by studies?

Output: 96  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long aft er sympt om onset can t he benefit s in r educed mor tality and improved functional out come w ere largely driv en by studies?. ### Response: 96  hours.


Instruction: How long can gery be aft er onset?

Output: 48  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long can gery be aft er onset?. ### Response: 48  hours.


Instruction: What is the maximum time for surgery?

Output: 48  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum time for surgery?. ### Response: 48  hours.


Instruction: How long is it agr eed to keep t he reference t to surgery being per formed?

Output: 48  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it agr eed to keep t he reference t to surgery being per formed?. ### Response: 48  hours.


Instruction: What year was NICE's str oke guideline published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was NICE's str oke guideline published?. ### Response: 2008.


Instruction: What is still appr opriat e and r eflect t he populations included in studies used to inform new recommendations?

Output: NICE's str oke guideline published in 2008 . It was agr eed t hat t hese

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is still appr opriat e and r eflect t he populations included in studies used to inform new recommendations?. ### Response: NICE's str oke guideline published in 2008 . It was agr eed t hat t hese.


Instruction: The committ ee agr eed to hat alt hough what remains uncer tain?

Output: hemicraniect omy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committ ee agr eed to hat alt hough what remains uncer tain?. ### Response: hemicraniect omy.


Instruction: Why should decompr essiv e hemicraniect omy be considered for some people?

Output: under  60

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why should decompr essiv e hemicraniect omy be considered for some people?. ### Response: under  60.


Instruction: What is impor tant decision making between een ph ysicians, sur geons, families and car ers?

Output: the high lik elihood of residual moderat e or se vere disability aft er sur gery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is impor tant decision making between een ph ysicians, sur geons, families and car ers?. ### Response: the high lik elihood of residual moderat e or se vere disability aft er sur gery.


Instruction: What is impor tant giv en the high lik elihood of residual moderat e or se vere disability aft er surgery?

Output: Shar ed decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is impor tant giv en the high lik elihood of residual moderat e or se vere disability aft er surgery?. ### Response: Shar ed decision making.


Instruction: What percentage of people on t he stride are on the stride?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of people on t he stride are on the stride?. ### Response: 5%.


Instruction: What percentage of people on t he str oke unit are referred for decompr essiv e hemicraniect omy?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of people on t he str oke unit are referred for decompr essiv e hemicraniect omy?. ### Response: 5%.


Instruction: What is currently consider ed for those aged under 60?

Output: Decompr essiv e hemicraniect omy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is currently consider ed for those aged under 60?. ### Response: Decompr essiv e hemicraniect omy.


Instruction: What will r equire e a change fr om current practice b y all pr oviders?

Output: r ecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will r equire e a change fr om current practice b y all pr oviders?. ### Response: r ecommendation.


Instruction: What will healt hcare professionals tak e into account people's pr e-stroke functional status?

Output: clear mor tality benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will healt hcare professionals tak e into account people's pr e-stroke functional status?. ### Response: clear mor tality benefit.


Instruction: What do the committee belie ve that including people o ver 60 years would not necessarily lead to significantly mor e people under going surgery?

Output: The committ ee therefore did not anticipat e a substantial r esour ce impact t o result fr om t his recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the committee belie ve that including people o ver 60 years would not necessarily lead to significantly mor e people under going surgery?. ### Response: The committ ee therefore did not anticipat e a substantial r esour ce impact t o result fr om t his recommendation.


Instruction: Why might inf ormed discussion of t he outcomes might r o r?

Output: including people o ver 60  years w ould not necessarily lead t o significant ly mor e people under going sur gery because inf ormed discussion of t he outcomes might r educe it s uptak e in t his population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why might inf ormed discussion of t he outcomes might r o r?. ### Response: including people o ver 60  years w ould not necessarily lead t o significant ly mor e people under going sur gery because inf ormed discussion of t he outcomes might r educe it s uptak e in t his population.


Instruction: Why might inf ormed discussion of t he outcomes might r educe it s uptak e in t his population?

Output: including people o ver 60  years w ould not necessarily lead t o significant ly mor e people under going sur gery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why might inf ormed discussion of t he outcomes might r educe it s uptak e in t his population?. ### Response: including people o ver 60  years w ould not necessarily lead t o significant ly mor e people under going sur gery.


Instruction: What is lik ely to decr ease t the population referred for decomprence?

Output: it s provision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lik ely to decr ease t the population referred for decomprence?. ### Response: it s provision.


Instruction: Who did not anticipate a substantial r esour ce impact t o result fr om t his recommendation?

Output: The committ ee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who did not anticipate a substantial r esour ce impact t o result fr om t his recommendation?. ### Response: The committ ee.


Instruction: Stroke and transient ischaemic attack in o ver 16s: diagnosis and treatment?

Output: management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stroke and transient ischaemic attack in o ver 16s: diagnosis and treatment?. ### Response: management.


Instruction: What is the name of the book that describes the diagnosis and initial management of stroke and transient ischaemic attack in o ver 16s?

Output: NG128

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes the diagnosis and initial management of stroke and transient ischaemic attack in o ver 16s?. ### Response: NG128.


Instruction: When was the last updat ed on 13 April 2022?

Output: Page 42of 48

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed on 13 April 2022?. ### Response: Page 42of 48.


Instruction: How long after an ACS is dual antiplatelet therapy recommended?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after an ACS is dual antiplatelet therapy recommended?. ### Response: 12 months.


Instruction: What is recommended during the fi rst 12 months after a ACS?

Output: Dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended during the fi rst 12 months after a ACS?. ### Response: Dual antiplatelet therapy.


Instruction: What type of stent is used in patients with AF?

Output: intracoronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stent is used in patients with AF?. ### Response: intracoronary.


Instruction: What is the CHADS 2 score of /H11350?

Output: high risk of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CHADS 2 score of /H11350?. ### Response: high risk of stroke.


Instruction: Why would many patients choose VKA therapy?

Output: to prevent future stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why would many patients choose VKA therapy?. ### Response: to prevent future stroke.


Instruction: What is the term for dual antiplatelet therapy?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for dual antiplatelet therapy?. ### Response: triple therapy.


Instruction: What is another term for triple therapy in AF and ACS?

Output: dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for triple therapy in AF and ACS?. ### Response: dual antiplatelet therapy.


Instruction: In addition to triple therapy, what is a treatment option for AF?

Output: warfarin plus dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to triple therapy, what is a treatment option for AF?. ### Response: warfarin plus dual antiplatelet therapy.


Instruction: What type of therapy may not be associated with net clinical benefit compared to dual antiplatelet therapy?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy may not be associated with net clinical benefit compared to dual antiplatelet therapy?. ### Response: triple therapy.


Instruction: Patients with AF and ACS who do not undergo placement of an intracoro-nary stent may not undergo what?

Output: warfarin plus dual antiplatelet therapy (ie, triple therapy), dual antiplatelet therapy, or warfarin plus single antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with AF and ACS who do not undergo placement of an intracoro-nary stent may not undergo what?. ### Response: warfarin plus dual antiplatelet therapy (ie, triple therapy), dual antiplatelet therapy, or warfarin plus single antiplatelet therapy.


Instruction: What is antiplatelet therapy unless patients are at substantially high risk of stroke?

Output: Dual antiplatelet therapy (eg, with aspirin and clopidogrel) rather than aspirin alone is recommended during the ﬁ  rst 12 months after an ACS, regardless of whether patients also receive an intracoronary stent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is antiplatelet therapy unless patients are at substantially high risk of stroke?. ### Response: Dual antiplatelet therapy (eg, with aspirin and clopidogrel) rather than aspirin alone is recommended during the ﬁ  rst 12 months after an ACS, regardless of whether patients also receive an intracoronary stent.


Instruction: The net benefi t at lower levels of stroke risk is uncertain?

Output: warfarin plus aspirin is at least as effec-tive, and potentially more effective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The net benefi t at lower levels of stroke risk is uncertain?. ### Response: warfarin plus aspirin is at least as effec-tive, and potentially more effective.


Instruction: What is a third therapeutic option in this clinical scenario?

Output: VKA plus single antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a third therapeutic option in this clinical scenario?. ### Response: VKA plus single antiplatelet therapy.


Instruction: What is the third therapeutic option?

Output: VKA plus single antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the third therapeutic option?. ### Response: VKA plus single antiplatelet therapy.


Instruction: What is not a concern in this clinical scenario?

Output: stent thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not a concern in this clinical scenario?. ### Response: stent thrombosis.


Instruction: There are no RCTs com-paring warfarin plus single antiplatelet therapy to what?

Output: dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are no RCTs com-paring warfarin plus single antiplatelet therapy to what?. ### Response: dual antiplatelet therapy.


Instruction: What is the relative risk of sub-sequent MI?

Output: 0.69

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relative risk of sub-sequent MI?. ### Response: 0.69.


Instruction: What is a 95% CI of 0.56-0.82?

Output: 0.63-1.18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 95% CI of 0.56-0.82?. ### Response: 0.63-1.18.


Instruction: How many patients post-ACS received aspirin alone?

Output: 121

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients post-ACS received aspirin alone?. ### Response: 121.


Instruction: What is the relative risk of clopidogrel plus aspirin?

Output: 0.77

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relative risk of clopidogrel plus aspirin?. ### Response: 0.77.


Instruction: What is a 95% CI?

Output: 0.63-1.18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 95% CI?. ### Response: 0.63-1.18.


Instruction: How are the reductions in MI and stroke seen?

Output: greater than those seen with clopidogrel plus aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the reductions in MI and stroke seen?. ### Response: greater than those seen with clopidogrel plus aspirin.


Instruction: What was the relative risk of Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) trial?

Output: 0.63-1.18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the relative risk of Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) trial?. ### Response: 0.63-1.18.


Instruction: What is warfarin plus aspirin at least as efficacious and potentially more effective than?

Output: clopidogrel plus aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is warfarin plus aspirin at least as efficacious and potentially more effective than?. ### Response: clopidogrel plus aspirin.


Instruction: Why was warfarin plus aspirin not given a recommendation?

Output: pragmatic issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was warfarin plus aspirin not given a recommendation?. ### Response: pragmatic issues.


Instruction: What was the reason for author and al not giving a recomendation?

Output: physician reluctance, burden of use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reason for author and al not giving a recomendation?. ### Response: physician reluctance, burden of use.


Instruction: Why did Author and al do not give a preference to dual antiplatelet therapy?

Output: there are no RCTs com-paring warfarin plus single antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did Author and al do not give a preference to dual antiplatelet therapy?. ### Response: there are no RCTs com-paring warfarin plus single antiplatelet therapy.


Instruction: What is the name of the 2012 American College of Chest Physicians by Kimberly Henricks?

Output: © 2012 American College of Chest Physicians by Kimberly Henricks on February 10, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2012 American College of Chest Physicians by Kimberly Henricks?. ### Response: © 2012 American College of Chest Physicians by Kimberly Henricks on February 10, 2012.


Instruction: On what date was this article published?

Output: February 10, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was this article published?. ### Response: February 10, 2012.


Instruction: How did the ERT coordinate the methodological and analytical processes of guideline development?

Output: grading the quality of the evidence per outcome, and grading thequality of the evidence for the recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the ERT coordinate the methodological and analytical processes of guideline development?. ### Response: grading the quality of the evidence per outcome, and grading thequality of the evidence for the recommendations.


Instruction: What was grading the quality of the evidence per outcome?

Output: GRADE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was grading the quality of the evidence per outcome?. ### Response: GRADE.


Instruction: Who was responsible for writing the recommendations and underlyingrationale?

Output: The Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was responsible for writing the recommendations and underlyingrationale?. ### Response: The Work Group.


Instruction: Who graded the strength of the recommendation?

Output: The Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who graded the strength of the recommendation?. ### Response: The Work Group.


Instruction: Where did the ERT have a one-day meeting in February 2018?

Output: Houston, Texas,USA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did the ERT have a one-day meeting in February 2018?. ### Response: Houston, Texas,USA.


Instruction: Where was the KDIGO Controversies Conference held in February 2018?

Output: Houston, Texas,USA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the KDIGO Controversies Conference held in February 2018?. ### Response: Houston, Texas,USA.


Instruction: What was the goal of the conference?

Output: to discuss the previous guideline and theﬁndings from the KDIGO Controversies Conference on BloodPressure in Chronic Kidney Disease,374andﬁnalize the guidelinedevelopment process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the goal of the conference?. ### Response: to discuss the previous guideline and theﬁndings from the KDIGO Controversies Conference on BloodPressure in Chronic Kidney Disease,374andﬁnalize the guidelinedevelopment process.


Instruction: Who finalized the draftguideline topics and review topics?

Output: the Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who finalized the draftguideline topics and review topics?. ### Response: the Work Group.


Instruction: Who determined the overall scope of the guideline?

Output: The guideline Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who determined the overall scope of the guideline?. ### Response: The guideline Work Group.


Instruction: What did the KDIGO Controversies Confer-ence on Blood Pressure in CKD inform?

Output: A preliminarylist of topics and key clinical questions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the KDIGO Controversies Confer-ence on Blood Pressure in CKD inform?. ### Response: A preliminarylist of topics and key clinical questions.


Instruction: What was developed to present a visual representation of the clinical question?

Output: Logical frameworks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed to present a visual representation of the clinical question?. ### Response: Logical frameworks.


Instruction: What format did clinical questions adhere to?

Output: RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What format did clinical questions adhere to?. ### Response: RCTs.


Instruction: What format was used to compile the list of critical and important outcomes?

Output: ICOM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What format was used to compile the list of critical and important outcomes?. ### Response: ICOM.


Instruction: Why were questions based on RCTs?

Output: to avoid bias by design

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were questions based on RCTs?. ### Response: to avoid bias by design.


Instruction: Who voted on the list of critical and important outcomes?

Output: the Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who voted on the list of critical and important outcomes?. ### Response: the Work Group.


Instruction: Who refined the clinical questions to finalize inclusion and exclusioncriteria?

Output: The Work Group and the ERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who refined the clinical questions to finalize inclusion and exclusioncriteria?. ### Response: The Work Group and the ERT.


Instruction: Clinicalquestions were mapped to existing what?

Output: Cochrane Kidney and Trans-plant systematic reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Clinicalquestions were mapped to existing what?. ### Response: Cochrane Kidney and Trans-plant systematic reviews.


Instruction: What did not map with any Cochrane Kidney and Transplant systematic reviews?

Output: clinical questions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not map with any Cochrane Kidney and Transplant systematic reviews?. ### Response: clinical questions.


Instruction: What was done for clinical questions that didn't map with a systematic review?

Output: de novo sys-tematic reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was done for clinical questions that didn't map with a systematic review?. ### Response: de novo sys-tematic reviews.


Instruction: To ensure all identi fid studies were included in the evi-dence review, what guideline was reviewed?

Output: The previous guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To ensure all identi fid studies were included in the evi-dence review, what guideline was reviewed?. ### Response: The previous guideline.


Instruction: What was included in the evi-dence review?

Output: all identi ﬁed studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was included in the evi-dence review?. ### Response: all identi ﬁed studies.


Instruction: What was conducted in accordance with the Cochrane Handbook?

Output: All evidence reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was conducted in accordance with the Cochrane Handbook?. ### Response: All evidence reviews.


Instruction: How were all evidence reviews conducted?

Output: in accordance tothe Cochrane Handbook

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were all evidence reviews conducted?. ### Response: in accordance tothe Cochrane Handbook.


Instruction: What did GRADE.384Literature searches and article selection do?

Output: guideline development adhered tothe standards

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did GRADE.384Literature searches and article selection do?. ### Response: guideline development adhered tothe standards.


Instruction: The Cochrane Kidney and Transplant Registry was searched for what?

Output: RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Cochrane Kidney and Transplant Registry was searched for what?. ### Response: RCTs.


Instruction: What is the cause of e366 Stroke?

Output: Symptomatic Intracranial Bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of e366 Stroke?. ### Response: Symptomatic Intracranial Bleeding.


Instruction: How long after IV Alteplase is symptomatic Intracranial Bleeding Occurring?

Output: 24 Hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after IV Alteplase is symptomatic Intracranial Bleeding Occurring?. ### Response: 24 Hours.


Instruction: What is PT (INR), fibrinogen level and type and cross-match?

Output: aPTT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PT (INR), fibrinogen level and type and cross-match?. ### Response: aPTT.


Instruction: What is the name of the nonenhanced head CTCryoprecipitate?

Output: factor VIII

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the nonenhanced head CTCryoprecipitate?. ### Response: factor VIII.


Instruction: How long does it take for fibrinogen level to peak?

Output: 12 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for fibrinogen level to peak?. ### Response: 12 h.


Instruction: What is another name for -aminocaproic acid?

Output: ε

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for -aminocaproic acid?. ### Response: ε.


Instruction: How long does it take for bleeding to be controlled?

Output: 3 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for bleeding to be controlled?. ### Response: 3 h.


Instruction: What is the peak onset of bleeding in 3 h?

Output: 1 g IV until bleeding is controlled

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the peak onset of bleeding in 3 h?. ### Response: 1 g IV until bleeding is controlled.


Instruction: What is not available in a timely manner?

Output: cryoprecipitate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not available in a timely manner?. ### Response: cryoprecipitate.


Instruction: What indicates acute ischemic stroke?

Output: AIS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates acute ischemic stroke?. ### Response: AIS.


Instruction: What is CPP?

Output: cerebral perfusion pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CPP?. ### Response: cerebral perfusion pressure.


Instruction: What is CT?

Output: computed tomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CT?. ### Response: computed tomography.


Instruction: ICP is intracranial pressure; what is INR?

Output: international normalized ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ICP is intracranial pressure; what is INR?. ### Response: international normalized ratio.


Instruction: IV is what?

Output: intravenous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: IV is what?. ### Response: intravenous.


Instruction: What may not be necessary if edema is limited to anterior tongue and lips?

Output: Endotracheal intubation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not be necessary if edema is limited to anterior tongue and lips?. ### Response: Endotracheal intubation.


Instruction: How long does it take for an edema to develop?

Output: within 30 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for an edema to develop?. ### Response: within 30 min.


Instruction: What is the best way to intubate a larynx?

Output: Awake fiberoptic intubation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the best way to intubate a larynx?. ### Response: Awake fiberoptic intubation.


Instruction: How is a cricothyroidotomy performed?

Output: rarely needed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is a cricothyroidotomy performed?. ### Response: rarely needed.


Instruction: What is the risk of epistaxis after IV alteplase?

Output: higher risk of requiring intubation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of epistaxis after IV alteplase?. ### Response: higher risk of requiring intubation.


Instruction: Cricothyroidotomy is rarely needed and also problematic after what?

Output: IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cricothyroidotomy is rarely needed and also problematic after what?. ### Response: IV alteplase.


Instruction: What should you do if there is an increase in angioedema?

Output: administer epinephrine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should you do if there is an increase in angioedema?. ### Response: administer epinephrine.


Instruction: How much epinephrine is administered subcutaneously?

Output: 0.3 mL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much epinephrine is administered subcutaneously?. ### Response: 0.3 mL.


Instruction: What is a selective bradykinin B2 receptor antagonist?

Output: LIcatibant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a selective bradykinin B2 receptor antagonist?. ### Response: LIcatibant.


Instruction: How many injections in 24 h is recommended?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many injections in 24 h is recommended?. ### Response: 3.


Instruction: What is the dose of plasma-derived C1 esterase inhibitor?

Output: 20 IU/kg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the dose of plasma-derived C1 esterase inhibitor?. ### Response: 20 IU/kg.


Instruction: How many IU/kg of C1 estrase inhibitor has been used successfully in hereditary angioedema?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many IU/kg of C1 estrase inhibitor has been used successfully in hereditary angioedema?. ### Response: 20.


Instruction: What is COR?

Output: class of recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is COR?. ### Response: class of recommendation.


Instruction: What is IV?

Output: intravenous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is IV?. ### Response: intravenous.


Instruction: What is the name of the study that investigated the effect of hospital volume on pros-thesis use and mortality in aortic valve operations in the elderly?

Output: Ann Tho-rac Surg.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effect of hospital volume on pros-thesis use and mortality in aortic valve operations in the elderly?. ### Response: Ann Tho-rac Surg..


Instruction: What is a key factor in identifying low-performing and high-performing AORtic valves?

Output: hospital volumes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key factor in identifying low-performing and high-performing AORtic valves?. ### Response: hospital volumes.


Instruction: In what year was 93:1107-12 published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was 93:1107-12 published?. ### Response: 2012.


Instruction: How many hospitals in the U.S. identify low-performing and high-performing aortic and aitral valve surgical cen-ters?

Output: volumes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hospitals in the U.S. identify low-performing and high-performing aortic and aitral valve surgical cen-ters?. ### Response: volumes.


Instruction: What is the JAMA Cardiol. 2017;2:1322-31?

Output: Role of hospital volumes in identifying low-performing and high-performing aortic and aitral valve surgical cen-ters in the United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JAMA Cardiol. 2017;2:1322-31?. ### Response: Role of hospital volumes in identifying low-performing and high-performing aortic and aitral valve surgical cen-ters in the United States.


Instruction: Who is Carroll JD, Vemulapalli S, Dai D, and others?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Carroll JD, Vemulapalli S, Dai D, and others?. ### Response: 6.


Instruction: What is the STS/ACC TVT registry?

Output: Procedural experience for transcath-eter aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the STS/ACC TVT registry?. ### Response: Procedural experience for transcath-eter aortic valve replacement.


Instruction: When was the registry downloaded from http://ahajournals.org?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the registry downloaded from http://ahajournals.org?. ### Response: April 28, 2023.


Instruction: Who is a Content Reviewer for the ACC/AHA Task Force on Clinical Practice Guidelines?

Output: Glenn N. Levine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Content Reviewer for the ACC/AHA Task Force on Clinical Practice Guidelines?. ### Response: Glenn N. Levine.


Instruction: Who is an Associate Professor of Medicine, Division of Cardiovascular Medicine/Electrophysiology?

Output: Zachary D. Goldberger

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is an Associate Professor of Medicine, Division of Cardiovascular Medicine/Electrophysiology?. ### Response: Zachary D. Goldberger.


Instruction: What is the Director of Mechanical Assisted Circulation, Gill Heart?

Output: Maya E. Guglin Content Reviewer—ACC HF and Transplant Section Leadership CouncilUniversity of Kentucky—Professor of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Director of Mechanical Assisted Circulation, Gill Heart?. ### Response: Maya E. Guglin Content Reviewer—ACC HF and Transplant Section Leadership CouncilUniversity of Kentucky—Professor of Medicine.


Instruction: Who is a professor of medicine at Mount Sinai Medical Center?

Output: Jonathan L. Halperin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a professor of medicine at Mount Sinai Medical Center?. ### Response: Jonathan L. Halperin.


Instruction: Who is an Associate Professor of Internal Medicine at Southwestern Medical Center University?

Output: José A. Joglar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is an Associate Professor of Internal Medicine at Southwestern Medical Center University?. ### Response: José A. Joglar.


Instruction: What is the name of the director of mechanical assisted circulculation at Gill Heart Institute?

Output: Maya E. Guglin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the director of mechanical assisted circulculation at Gill Heart Institute?. ### Response: Maya E. Guglin.


Instruction: What is Michael E. DeBakey Medical Center's title?

Output: Director

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Michael E. DeBakey Medical Center's title?. ### Response: Director.


Instruction: Who is the Director of the Cardiac Care Unit?

Output: Michael E. DeBakey Medical Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of the Cardiac Care Unit?. ### Response: Michael E. DeBakey Medical Center.


Instruction: What is the name of the content reviewer for the ACC HF and Transplant Section Leadership Council?

Output: Maya E. Guglin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the content reviewer for the ACC HF and Transplant Section Leadership Council?. ### Response: Maya E. Guglin.


Instruction: What was the name of the pilot study?

Output: Hypertension in the Very Elderly Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the pilot study?. ### Response: Hypertension in the Very Elderly Trial.


Instruction: What is the JATOS Study?

Output: Japanese trial to assessoptimal systolic blood pressure in elderly hypertensive patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JATOS Study?. ### Response: Japanese trial to assessoptimal systolic blood pressure in elderly hypertensive patients.


Instruction: When was the J Hypertens study published?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Hypertens study published?. ### Response: 2005.


Instruction: What is the name of the Japanese trial to assessoptimal systolic blood pressure in elderly hypertensive patients?

Output: JATOS Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Japanese trial to assessoptimal systolic blood pressure in elderly hypertensive patients?. ### Response: JATOS Study Group.


Instruction: When was the JATOS Study Group founded?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JATOS Study Group founded?. ### Response: 1996.


Instruction: What is the target blood pressure for treatment of in isolated systolic hypertension in the elderly?

Output: valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target blood pressure for treatment of in isolated systolic hypertension in the elderly?. ### Response: valsartan.


Instruction: Hypertension 2010; 56:196–202.395.

Output: Home sphygmomanometers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertension 2010; 56:196–202.395.. ### Response: Home sphygmomanometers.


Instruction: What was the ACCF/AHA 2011 expert consensus?

Output: hypertension in the elderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the ACCF/AHA 2011 expert consensus?. ### Response: hypertension in the elderly.


Instruction: What was the name of the Task Force on Clinical ExpertConsensus Documents?

Output: AmericanCollege of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the Task Force on Clinical ExpertConsensus Documents?. ### Response: AmericanCollege of Cardiology Foundation.


Instruction: What was developed in collaboration with the AmericanAcademy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology and European Society of Hypertension?

Output: Consensus Documents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed in collaboration with the AmericanAcademy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology and European Society of Hypertension?. ### Response: Consensus Documents.


Instruction: What is the European Society of Hypertension?

Output: practice guidelines for home blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the European Society of Hypertension?. ### Response: practice guidelines for home blood pressure monitoring.


Instruction: What are the names of the authors of the Renal Association Clinical Practice Guideline ondetection, monitoring and management of patients withCKD?

Output: MacGregor MS, Taal MW

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the Renal Association Clinical Practice Guideline ondetection, monitoring and management of patients withCKD?. ### Response: MacGregor MS, Taal MW.


Instruction: What is the name of the journal that studies the treatment of hypertension in the elderly?

Output: J Clin Hypertens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the treatment of hypertension in the elderly?. ### Response: J Clin Hypertens.


Instruction: When was the J Clin Hypertens (Greenwich) 2008 published?

Output: 10: 58– 68.398

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Clin Hypertens (Greenwich) 2008 published?. ### Response: 10: 58– 68.398.


Instruction: What does alcohol consumption and kidney function decline in elderly people have in common?

Output: alcohol and kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does alcohol consumption and kidney function decline in elderly people have in common?. ### Response: alcohol and kidney disease.


Instruction: What is the name of the journal that studies health-related quality of life outcomes in chronic kidney disease?

Output: Curr Opin Nephrol Hy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies health-related quality of life outcomes in chronic kidney disease?. ### Response: Curr Opin Nephrol Hy.


Instruction: How many pages are in the Curr Opin Nephrol Hypertenss 2010?

Output: 19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages are in the Curr Opin Nephrol Hypertenss 2010?. ### Response: 19.


Instruction: What are the names of the journals that study the health of older adults in relation to chronic kidney diseases?

Output: American Geriatrics Society, American Societyfor Preventive Cardiology, American Society of Hypertension, AmericanSociety of Nephrology, Association of Black Cardiologists, and EuropeanSociety of Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the journals that study the health of older adults in relation to chronic kidney diseases?. ### Response: American Geriatrics Society, American Societyfor Preventive Cardiology, American Society of Hypertension, AmericanSociety of Nephrology, Association of Black Cardiologists, and EuropeanSociety of Hypertension.


Instruction: What should a nephrologist know about home sphygmomanometers?

Output: guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a nephrologist know about home sphygmomanometers?. ### Response: guidelines.


Instruction: What are the practice guidelines of the European Society of Hypertension for?

Output: home blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the practice guidelines of the European Society of Hypertension for?. ### Response: home blood pressure monitoring.


Instruction: What should a nephrologistknow?

Output: Home sphygmomanometers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a nephrologistknow?. ### Response: Home sphygmomanometers.


Instruction: What are the European Society of Hypertensionpractice guidelines for home blood pressure monitoring?

Output: Stergiou GS, Asmar R et al.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the European Society of Hypertensionpractice guidelines for home blood pressure monitoring?. ### Response: Stergiou GS, Asmar R et al..


Instruction: How long did it take for arterial stiffness to increase in normotensive subjects?

Output: 6-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for arterial stiffness to increase in normotensive subjects?. ### Response: 6-year.


Instruction: What is the Circulation 2002 105:1202-1207.405?

Output: Determinants of acceleratedprogression of arterial stiffness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Circulation 2002 105:1202-1207.405?. ### Response: Determinants of acceleratedprogression of arterial stiffness.


Instruction: How long was the period of time between the acceleratedprogression and the treatment of hypertension?

Output: 6-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the period of time between the acceleratedprogression and the treatment of hypertension?. ### Response: 6-year.


Instruction: In what year was the Kidney Int 59: 1834-1841?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Kidney Int 59: 1834-1841?. ### Response: 2001.


Instruction: What year was Kidney Int 59: 1834–1841.406?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Kidney Int 59: 1834–1841.406?. ### Response: 2001.


Instruction: What is the name of the ambulatory device used in 2001?

Output: Kidney

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ambulatory device used in 2001?. ### Response: Kidney.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 52 of 127 following studies were not included in the systematic evidence review?

Output: strength of this recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 52 of 127 following studies were not included in the systematic evidence review?. ### Response: strength of this recommendation.


Instruction: How much of a dherence to statin therapy is estimated at one year?

Output: < 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of a dherence to statin therapy is estimated at one year?. ### Response: < 50%.


Instruction: What is the decline in adherence after two years?

Output: < 30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the decline in adherence after two years?. ### Response: < 30%.


Instruction: How many sociodemographic characteristics do statin patients have?

Output: < 50 years or >70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sociodemographic characteristics do statin patients have?. ### Response: < 50 years or >70 years.


Instruction: How long have African American and Hispanic patients been associated with lower statin adherence rates?

Output: >70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long have African American and Hispanic patients been associated with lower statin adherence rates?. ### Response: >70 years.


Instruction: How many patients with prior CVD being treated at the VA showed the risk of mortality was increased by 30%?

Output: 304,104

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with prior CVD being treated at the VA showed the risk of mortality was increased by 30%?. ### Response: 304,104.


Instruction: How much was the risk of mortality increased by VA in those with adherence of  50% based on r efill history?

Output: 30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the risk of mortality increased by VA in those with adherence of  50% based on r efill history?. ### Response: 30%.


Instruction: What was found to be associated with a 5% decreased risk of CV -related hospit alizations?

Output: 10% increase in adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to be associated with a 5% decreased risk of CV -related hospit alizations?. ### Response: 10% increase in adherence.


Instruction: What is a complex, multifactorial issue that involves the entire healthcare system?

Output: Medication  adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a complex, multifactorial issue that involves the entire healthcare system?. ### Response: Medication  adherence.


Instruction: What factors negatively impact adherence?

Output: Patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What factors negatively impact adherence?. ### Response: Patient.


Instruction: What did the patient focus group emphasize to improve their understanding of treatment?

Output: the need for stronger provider -patient communication and additional education

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the patient focus group emphasize to improve their understanding of treatment?. ### Response: the need for stronger provider -patient communication and additional education.


Instruction: What type of evidence did the Work Group review?

Output: Reviewed , New -added recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of evidence did the Work Group review?. ### Response: Reviewed , New -added recommendation.


Instruction: The Work Group reviewed evidence related to what recommendation?

Output: Reviewed , New -added recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Work Group reviewed evidence related to what recommendation?. ### Response: Reviewed , New -added recommendation.


Instruction: What was the Work Group's confidence in the quality of the evidence?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Work Group's confidence in the quality of the evidence?. ### Response: low.


Instruction: The body of evidence had some limitations, including what?

Output: lack of blinding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The body of evidence had some limitations, including what?. ### Response: lack of blinding.


Instruction: What were no harms identified in the systematic review?

Output: there is a significant benefit of improved adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were no harms identified in the systematic review?. ### Response: there is a significant benefit of improved adherence.


Instruction: What is a significant benefit of improved adherence?

Output: decreased risk of CV -related hospit alizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a significant benefit of improved adherence?. ### Response: decreased risk of CV -related hospit alizations.


Instruction: Other considerations regarding this recommendation are what?

Output: the cost and availability of resources

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Other considerations regarding this recommendation are what?. ### Response: the cost and availability of resources.


Instruction: What did the Work Group decide upon because there were no harms identified and given the potential benefits of medication adherence?

Output: a  “Weak for” recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group decide upon because there were no harms identified and given the potential benefits of medication adherence?. ### Response: a  “Weak for” recommendation.


Instruction: What was the "Weak for" recommendation?

Output: Because there were no harms identified and given the potential benefits of medication adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the "Weak for" recommendation?. ### Response: Because there were no harms identified and given the potential benefits of medication adherence.


Instruction: What is Lifestyle Interventions Recommendation 25?

Output: For primary and secondary prevention of cardiovascular disease, we suggest a dietitian- led Mediterranean diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Lifestyle Interventions Recommendation 25?. ### Response: For primary and secondary prevention of cardiovascular disease, we suggest a dietitian- led Mediterranean diet.


Instruction: What do we suggest for primary and secondary prevention of cardiovascular disease?

Output: a dietitian- led Mediterranean diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest for primary and secondary prevention of cardiovascular disease?. ### Response: a dietitian- led Mediterranean diet.


Instruction: Who led the Mediterranean diet?

Output: dietitian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who led the Mediterranean diet?. ### Response: dietitian.


Instruction: How many RCTs did Hooper and colleagues review in 2015?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs did Hooper and colleagues review in 2015?. ### Response: 15.


Instruction: How many RCTs found that reducing saturated fat did not re duce CVD mortality?

Output: eight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs found that reducing saturated fat did not re duce CVD mortality?. ### Response: eight.


Instruction: A systematic review by Rees et al. (2019) found that a Mediterranean diet reduce d composite C V events, what did they say?

Output: < 50% at one year with further decline to < 30% after two years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A systematic review by Rees et al. (2019) found that a Mediterranean diet reduce d composite C V events, what did they say?. ### Response: < 50% at one year with further decline to < 30% after two years.


Instruction: What should patients with stage 2 hypertension and BP 160/100 mm Hg be treated for?

Output: upward medication dose adjustment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with stage 2 hypertension and BP 160/100 mm Hg be treated for?. ### Response: upward medication dose adjustment.


Instruction: How long after initiating therapy should patients undergo upward medication dose adjustment?

Output: 2 to 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after initiating therapy should patients undergo upward medication dose adjustment?. ### Response: 2 to 4 weeks.


Instruction: What should be promptly treated, carefully monitored and subject to?

Output: Patients with stage 2 hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be promptly treated, carefully monitored and subject to?. ### Response: Patients with stage 2 hypertension.


Instruction: What type of hypotension can be detected in older patients?

Output: orthostatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypotension can be detected in older patients?. ### Response: orthostatic.


Instruction: What is a reassessment of BP?

Output: BP measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reassessment of BP?. ### Response: BP measurement.


Instruction: What does ACC stand for?

Output: American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACC stand for?. ### Response: American College of Cardiology.


Instruction: What is the acronym for atherosclerotic cardiovascular disease?

Output: ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for atherosclerotic cardiovascular disease?. ### Response: ASCVD.


Instruction: AHA stands for what?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AHA stands for what?. ### Response: American Heart Association.


Instruction: What does ASCVD mean?

Output: atherosclerotic cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ASCVD mean?. ### Response: atherosclerotic cardiovascular disease.


Instruction: What does BP stand for?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does BP stand for?. ### Response: blood pressure.


Instruction: Where can ahajournals.org be found?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can ahajournals.org be found?. ### Response: http://ahajournals.org.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett et al.


Instruction: When did Arnett publish his guideline on primary prevention of cardiovascular disease?

Output: September 10, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Arnett publish his guideline on primary prevention of cardiovascular disease?. ### Response: September 10, 2019.


Instruction: What is a risk factor for ASCVD?

Output: strong family history of premature MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for ASCVD?. ### Response: strong family history of premature MI.


Instruction: What may a given patient and his/her clinician decide that lowering the risk of MI is important?

Output: risk factors present

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may a given patient and his/her clinician decide that lowering the risk of MI is important?. ### Response: risk factors present.


Instruction: What is the risk of MI not captured by clinical trials of 5 to 10 years’ duration?

Output: potentially serious long-term conse-quences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of MI not captured by clinical trials of 5 to 10 years’ duration?. ### Response: potentially serious long-term conse-quences.


Instruction: Recent trials show that absolute risk for ASCVD events typically exceeds that of bleed-ing?

Output: Arnett et al 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent trials show that absolute risk for ASCVD events typically exceeds that of bleed-ing?. ### Response: Arnett et al 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease.


Instruction: What does absolute risk for ASCVD events typically exceed?

Output: that of bleed-ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does absolute risk for ASCVD events typically exceed?. ### Response: that of bleed-ing.


Instruction: The gap of relative benefit to relative harm for aspirin has narrowed, but the num-ber needed to treat remains lower than what?

Output: the number needed to harm to cause bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The gap of relative benefit to relative harm for aspirin has narrowed, but the num-ber needed to treat remains lower than what?. ### Response: the number needed to harm to cause bleeding.


Instruction: What may feel that the number needed to harm to cause bleeding remains lower?

Output: adults >70 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may feel that the number needed to harm to cause bleeding remains lower?. ### Response: adults >70 years of age.


Instruction: To harm to cause bleeding?

Output: higher with high-dose aspi-rin. Recent observational studies motivate future research on the personalization of prophylactic aspirin dose according to patient-specific factors (eg, weight),S4.6-22 though we note that, regarding weight specifically, there was no evidence low-dose aspirin was any more effective in low-weight individuals than in high-weight individuals in the more recently published ASCEND (A Study of Cardiovascular Events iN Diabetes) trial,S4.6-16 trial. Most importantly, recent clinical trials also teach us that low-dose prophylactic aspirin may be best justified among persons at high ASCVD risk who cannot achieve optimal control of other ASCVD risk factors.S4.6-232. Prophylactic aspirin in primary-prevention adults >70 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To harm to cause bleeding?. ### Response: higher with high-dose aspi-rin. Recent observational studies motivate future research on the personalization of prophylactic aspirin dose according to patient-specific factors (eg, weight),S4.6-22 though we note that, regarding weight specifically, there was no evidence low-dose aspirin was any more effective in low-weight individuals than in high-weight individuals in the more recently published ASCEND (A Study of Cardiovascular Events iN Diabetes) trial,S4.6-16 trial. Most importantly, recent clinical trials also teach us that low-dose prophylactic aspirin may be best justified among persons at high ASCVD risk who cannot achieve optimal control of other ASCVD risk factors.S4.6-232. Prophylactic aspirin in primary-prevention adults >70 years of age.


Instruction: What is more suitable than a Class III recommendation for adults 40 years old?

Output: Class IIb recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more suitable than a Class III recommendation for adults 40 years old?. ### Response: Class IIb recommendation.


Instruction: What is more suitable than a Class III recommendation for adults 40 to 70 years of age?

Output: Class IIb recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more suitable than a Class III recommendation for adults 40 to 70 years of age?. ### Response: Class IIb recommendation.


Instruction: What is there limited justifica-tion to use aspirin at doses >100 mg daily for pri-mary prevention?

Output: prophylactic aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there limited justifica-tion to use aspirin at doses >100 mg daily for pri-mary prevention?. ### Response: prophylactic aspirin.


Instruction: Meta-analyses suggest that the ASCVD risk is what?

Output: exceeds that of bleed-ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Meta-analyses suggest that the ASCVD risk is what?. ### Response: exceeds that of bleed-ing.


Instruction: What is the ASCVD risk benefit for low-dose aspirin equivalent to?

Output: that for high-dose aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ASCVD risk benefit for low-dose aspirin equivalent to?. ### Response: that for high-dose aspirin.


Instruction: What is higher with high-dose aspi-rin?

Output: bleeding risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is higher with high-dose aspi-rin?. ### Response: bleeding risk.


Instruction: Recent observational studies motivate future research on the personalization of what?

Output: prophylactic aspirin dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent observational studies motivate future research on the personalization of what?. ### Response: prophylactic aspirin dose.


Instruction: What did the ASCEND (A Study of Cardiovascular Events iN Diabetes) trial show was more effective in low-weight people than in high-weight individuals?

Output: low-dose aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ASCEND (A Study of Cardiovascular Events iN Diabetes) trial show was more effective in low-weight people than in high-weight individuals?. ### Response: low-dose aspirin.


Instruction: What is the S4.6-16 trial?

Output: ASCEND (A Study of Cardiovascular Events iN Diabetes) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the S4.6-16 trial?. ### Response: ASCEND (A Study of Cardiovascular Events iN Diabetes) trial.


Instruction: What may be best justified among people at high ASCVD risk?

Output: low-dose prophylactic aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be best justified among people at high ASCVD risk?. ### Response: low-dose prophylactic aspirin.


Instruction: Who can't achieve optimal control of other risk factors?

Output: persons at high ASCVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who can't achieve optimal control of other risk factors?. ### Response: persons at high ASCVD risk.


Instruction: What is the risk of bleeding in primary-prevention adults >70 years of age?

Output: higher risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of bleeding in primary-prevention adults >70 years of age?. ### Response: higher risk.


Instruction: What is not enough evidence to judge the risk-benefit ratio of routine aspirin for adults 40 years?

Output: there was no evidence low-dose aspirin was any more effective in low-weight individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not enough evidence to judge the risk-benefit ratio of routine aspirin for adults 40 years?. ### Response: there was no evidence low-dose aspirin was any more effective in low-weight individuals.


Instruction: What is the risk-benefit ratio of routine aspirin for primary prevention of ASCVD?

Output: lower than the number needed to harm to cause bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk-benefit ratio of routine aspirin for primary prevention of ASCVD?. ### Response: lower than the number needed to harm to cause bleeding.


Instruction: Routine use is not recommended in these settings, but there is evidence to judge what?

Output: ASCVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Routine use is not recommended in these settings, but there is evidence to judge what?. ### Response: ASCVD risk.


Instruction: What does the addition of ezetimibe or bile acid sequestrants to statin therapy typically provide an additional 15% to 25% reduction in?

Output: LDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the addition of ezetimibe or bile acid sequestrants to statin therapy typically provide an additional 15% to 25% reduction in?. ### Response: LDL-C.


Instruction: What is a PCSK9 inhibitor added to statin plus ezetimibe?

Output: additive reductions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a PCSK9 inhibitor added to statin plus ezetimibe?. ### Response: additive reductions.


Instruction: How long after starting a statin or combined therapy will the maximum percentage change occur?

Output: 4 to 12 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after starting a statin or combined therapy will the maximum percentage change occur?. ### Response: 4 to 12 weeks.


Instruction: What is the most common combination of lifestyle and statin therapy?

Output: statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common combination of lifestyle and statin therapy?. ### Response: statin.


Instruction: What will make it possible to confirm adherence to therapy?

Output: Periodic remeasurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will make it possible to confirm adherence to therapy?. ### Response: Periodic remeasurements.


Instruction: What will vary in adolescents, young adults, and adults 40 to 75 years of age?

Output: recommended intensities of drug thera-pies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will vary in adolescents, young adults, and adults 40 to 75 years of age?. ### Response: recommended intensities of drug thera-pies.


Instruction: What are the recommended LDL-C levels for adults 40 to 75 years of age?

Output: 70

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommended LDL-C levels for adults 40 to 75 years of age?. ### Response: 70.


Instruction: In addition to young adults and those with severe hyper -cholesterolemia, what is another age group?

Output: adults 40 to 75 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to young adults and those with severe hyper -cholesterolemia, what is another age group?. ### Response: adults 40 to 75 years of age.


Instruction: What are additional recommendations for adults >75 years?

Output: Section 4.1. (Secondary ASCVD Pre-vention) and Section 4.3. (Diabetes Mellitus in Adults).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are additional recommendations for adults >75 years?. ### Response: Section 4.1. (Secondary ASCVD Pre-vention) and Section 4.3. (Diabetes Mellitus in Adults)..


Instruction: How old are adults included in Section 4.1?

Output: >75 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are adults included in Section 4.1?. ### Response: >75 years of age.


Instruction: What is Section 4.3?

Output: Diabetes Mellitus in Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Section 4.3?. ### Response: Diabetes Mellitus in Adults.


Instruction: Where are references to studies that support recommendations summarized?

Output: Online Data Supplements 18 and 19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are references to studies that support recommendations summarized?. ### Response: Online Data Supplements 18 and 19.


Instruction: What may be reasonable in adults 75 years of age or older with an LDL-C level of 70 to 189 mg/dL?

Output: initiating a moderate-intensity statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable in adults 75 years of age or older with an LDL-C level of 70 to 189 mg/dL?. ### Response: initiating a moderate-intensity statin.


Instruction: What is the LDL-C level in adults 76 to 80 years of age?

Output: 70 to 189 mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LDL-C level in adults 76 to 80 years of age?. ### Response: 70 to 189 mg/dL.


Instruction: What limits the potential benefits of statin therapy?

Output: functional decline (physical or cognitive), multimorbidity, frailty, or reduced life-expectancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What limits the potential benefits of statin therapy?. ### Response: functional decline (physical or cognitive), multimorbidity, frailty, or reduced life-expectancy.


Instruction: How many mg/dL is the CAC score?

Output: zero

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg/dL is the CAC score?. ### Response: zero.


Instruction: What is en-demic in the rapidly growing population of older adults?

Output: Mounting risk factors and subclinical disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is en-demic in the rapidly growing population of older adults?. ### Response: Mounting risk factors and subclinical disease.


Instruction: How old are older adults more susceptible to statin-related diseases?

Output: 40 to 75 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are older adults more susceptible to statin-related diseases?. ### Response: 40 to 75 years of age.


Instruction: What does RCTS4.4.4.1-1-S4.4.41-4 support?

Output: primary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does RCTS4.4.4.1-1-S4.4.41-4 support?. ### Response: primary prevention.


Instruction: How old is the data in older subsets?

Output: ≥80 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is the data in older subsets?. ### Response: ≥80 years of age.


Instruction: As adults grow older, they are more susceptible to what?

Output: statin-related risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: As adults grow older, they are more susceptible to what?. ### Response: statin-related risks.


Instruction: What are some of the side effects of statins?

Output: multimorbidity, polypharmacy, frailty, and cognitive decline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the side effects of statins?. ### Response: multimorbidity, polypharmacy, frailty, and cognitive decline.


Instruction: In some patients, the risks associated with statin may exceed what in some patients?

Output: their likely benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In some patients, the risks associated with statin may exceed what in some patients?. ### Response: their likely benefits.


Instruction: What may exceed the likely benefits of statins for some patients?

Output: the aggregate risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may exceed the likely benefits of statins for some patients?. ### Response: the aggregate risks.


Instruction: What is the name of the study in which the Norwegian population was adjusted by age and sex?

Output: Coronary artery bypasssurgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study in which the Norwegian population was adjusted by age and sex?. ### Response: Coronary artery bypasssurgery.


Instruction: What influence did gender have on the outcome of coronary artery bypass surgery?

Output: independent predictor of operative mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What influence did gender have on the outcome of coronary artery bypass surgery?. ### Response: independent predictor of operative mortality.


Instruction: What is the influence of gender on the outcome of coronary artery bypass surgery?

Output: significant improvement inshort-term mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the influence of gender on the outcome of coronary artery bypass surgery?. ### Response: significant improvement inshort-term mortality.


Instruction: What is a systematic review of gender differences in mortality after coronaryartery bypass graft surgery andpercutaneous coronary interventions?

Output: berg RF, Pavlic T, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of gender differences in mortality after coronaryartery bypass graft surgery andpercutaneous coronary interventions?. ### Response: berg RF, Pavlic T, et al.


Instruction: What is an independent predictor of operative mortality after coronary artery bypass graft surgery?

Output: Female gender

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an independent predictor of operative mortality after coronary artery bypass graft surgery?. ### Response: Female gender.


Instruction: How many Midwestern hospitals did Blankstein R, Ward RP, Arnsdorf M, et al. analyze?

Output: 31

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Midwestern hospitals did Blankstein R, Ward RP, Arnsdorf M, et al. analyze?. ### Response: 31.


Instruction: What is the gender of the patient?

Output: Female

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the gender of the patient?. ### Response: Female.


Instruction: When was Circulation published?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation published?. ### Response: 1993.


Instruction: What is the cause of poor outcomes of coronary artery bypass operations in women?

Output: body size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of poor outcomes of coronary artery bypass operations in women?. ### Response: body size.


Instruction: What are the results of the Cali-fornia Coronary Artery Bypass Grafting Outcomes Reporting Program?

Output: Operative mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the Cali-fornia Coronary Artery Bypass Grafting Outcomes Reporting Program?. ### Response: Operative mortality.


Instruction: What is the name of the procedure performed in women?

Output: Coronary artery bypasssurgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure performed in women?. ### Response: Coronary artery bypasssurgery.


Instruction: What are the results of coronary artery bypass grafting?

Output: Patterns of referral and recovery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of coronary artery bypass grafting?. ### Response: Patterns of referral and recovery.


Instruction: When was the last time a woman had a coronary bypass operation?

Output: 1991 to 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a woman had a coronary bypass operation?. ### Response: 1991 to 2004.


Instruction: What is the name of the group that investigates thrombolysis in myocardialinfarction?

Output: TIMI Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that investigates thrombolysis in myocardialinfarction?. ### Response: TIMI Investigators.


Instruction: What is a significant improvement in short-term mortality in women undergoing coronary artery bypasssurgery?

Output: 1991 to 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a significant improvement in short-term mortality in women undergoing coronary artery bypasssurgery?. ### Response: 1991 to 2004.


Instruction: What type of surgery was performed from 1991 to 2004?

Output: coronary artery bypass

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery was performed from 1991 to 2004?. ### Response: coronary artery bypass.


Instruction: What is the name of the study group that studied the Northern New England Cardiovascular Disease Study Group?

Output: O’Connor GT, Morton JR, Diehl MJ, et al.,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studied the Northern New England Cardiovascular Disease Study Group?. ### Response: O’Connor GT, Morton JR, Diehl MJ, et al.,.


Instruction: What is the name of the procedure used to treat small vessel disease in women?

Output: Multiarterial coronary arterybypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used to treat small vessel disease in women?. ### Response: Multiarterial coronary arterybypass grafting.


Instruction: When was Eur Heart J.14:634-9.1148 published?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Eur Heart J.14:634-9.1148 published?. ### Response: 1993.


Instruction: What is gender and mortality risk on the waiting list for coronary artery bypass grafting?

Output: Female

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is gender and mortality risk on the waiting list for coronary artery bypass grafting?. ### Response: Female.


Instruction: What is a list for for coronary artery bypass grafting?

Output: waiting list

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a list for for coronary artery bypass grafting?. ### Response: waiting list.


Instruction: What is the Eur J Car-diothorac Surg 2004:26:521–7.1149?

Output: coronary artery bypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Eur J Car-diothorac Surg 2004:26:521–7.1149?. ### Response: coronary artery bypass grafting.


Instruction: Who is the author of Patterns of referral and recovery?

Output: King KB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Patterns of referral and recovery?. ### Response: King KB.


Instruction: What type of surgery is performed in older women and men?

Output: Coronary artery bypass

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery is performed in older women and men?. ### Response: Coronary artery bypass.


Instruction: What is the name of the study that investigated gender differences in cardiac procedures and medication use for acute myocardial infarction?

Output: AmHeart J.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated gender differences in cardiac procedures and medication use for acute myocardial infarction?. ### Response: AmHeart J..