Instruction: What is the conversion success rate for agents such as verapamil, diltiazem, and adenosine?

Output: 80% to 98%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the conversion success rate for agents such as verapamil, diltiazem, and adenosine?. ### Response: 80% to 98%.


Instruction: What might prove effective in some resistant cases?

Output: a second drug bolus or higher dose of initial drug agent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might prove effective in some resistant cases?. ### Response: a second drug bolus or higher dose of initial drug agent.


Instruction: In rare instances, drugs may fail to restore what?

Output: sinus rhythm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In rare instances, drugs may fail to restore what?. ### Response: sinus rhythm.


Instruction: What is inappropriate if the SVT is terminating and reinitiating spontaneously?

Output: Synchronized cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is inappropriate if the SVT is terminating and reinitiating spontaneously?. ### Response: Synchronized cardioversion.


Instruction: What can be effective for acute treatment in patients with hemodynamically stable SVT?

Output: Synchronized cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be effective for acute treatment in patients with hemodynamically stable SVT?. ### Response: Synchronized cardioversion.


Instruction: How many lozenges of gum do you need?

Output: 24

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many lozenges of gum do you need?. ### Response: 24.


Instruction: How long before and after use is it possible to have iccups or dyspepsia?

Output: 15 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before and after use is it possible to have iccups or dyspepsia?. ### Response: 15 min.


Instruction: What is the maximum dose of nasal spray?

Output: 10 mg/mL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum dose of nasal spray?. ### Response: 10 mg/mL.


Instruction: What is a possible cause of irritation in an inhaler?

Output: nasal or reactive airway disorders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible cause of irritation in an inhaler?. ### Response: nasal or reactive airway disorders.


Instruction: What is another name for Wellbutrin SR?

Output: GlaxoSmithKline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Wellbutrin SR?. ### Response: GlaxoSmithKline.


Instruction: How many cartridges per day is the maximum dose?

Output: 16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cartridges per day is the maximum dose?. ### Response: 16.


Instruction: How long does it take to take 150 mg twice daily?

Output: 3 d

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to take 150 mg twice daily?. ### Response: 3 d.


Instruction: What is the recommended dose of NRTS4.5-21Avoid with history/risk of seizures, eating disorders, MAO inhibitors, or CYP 2D6 inhibitorVarenicline?

Output: 0.5 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended dose of NRTS4.5-21Avoid with history/risk of seizures, eating disorders, MAO inhibitors, or CYP 2D6 inhibitorVarenicline?. ### Response: 0.5 mg.


Instruction: How long does it take to take 0.5 mg twice daily for 4 d?

Output: 1 mg twice daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to take 0.5 mg twice daily for 4 d?. ### Response: 1 mg twice daily.


Instruction: How often do you take 1 mg twice a day for 3-6 moNausea common; take with what?

Output: food

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often do you take 1 mg twice a day for 3-6 moNausea common; take with what?. ### Response: food.


Instruction: What can guide dosing?

Output: CPD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can guide dosing?. ### Response: CPD.


Instruction: What is a guide dosing of 1 CPD?

Output: ≈1-2 mg of nicotine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a guide dosing of 1 CPD?. ### Response: ≈1-2 mg of nicotine.


Instruction: How many mg of nicotine is 1-2 mg of?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg of nicotine is 1-2 mg of?. ### Response: ≈.


Instruction: What are patients who are pregnant or breastfeeding advised to use with NRT products?

Output: nicotine replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients who are pregnant or breastfeeding advised to use with NRT products?. ### Response: nicotine replacement.


Instruction: What can be titrated on the basis of response?

Output: Dose and duration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be titrated on the basis of response?. ### Response: Dose and duration.


Instruction: The FDA has issued a removal of what warnings about neuropsychiatric events?

Output: black box

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The FDA has issued a removal of what warnings about neuropsychiatric events?. ### Response: black box.


Instruction: What is the acronym for monoamine oxidase?

Output: MAO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for monoamine oxidase?. ### Response: MAO.


Instruction: What does NRT stand for?

Output: nicotine replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NRT stand for?. ### Response: nicotine replacement.


Instruction: When was the version of Diseases, Tenth Revision released?

Output: ICD-10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the version of Diseases, Tenth Revision released?. ### Response: ICD-10.


Instruction: What can be useful for follow-up assessment at 2-year or longer inter-vals in patients with SIHD with prior evidence ofsilent ischemia or who are at high risk for a recur-rent cardiac event?

Output: Nuclear MPI, echocardiography, or CMR with ei-ther exercise or pharmacological stress

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be useful for follow-up assessment at 2-year or longer inter-vals in patients with SIHD with prior evidence ofsilent ischemia or who are at high risk for a recur-rent cardiac event?. ### Response: Nuclear MPI, echocardiography, or CMR with ei-ther exercise or pharmacological stress.


Instruction: Nuclear MPI, echocardiography, or CMR with ei-ther exercise or pharmacological stress can be used in what type of patient?

Output: patients with SIHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nuclear MPI, echocardiography, or CMR with ei-ther exercise or pharmacological stress can be used in what type of patient?. ### Response: patients with SIHD.


Instruction: What is the level of evidence for incomplete coronaryrevascularization?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for incomplete coronaryrevascularization?. ### Response: C.


Instruction: What might be considered for follow-upassessment in patients with SIHD who have an uninterpretableECG?

Output: evaluation ofincomplete revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered for follow-upassessment in patients with SIHD who have an uninterpretableECG?. ### Response: evaluation ofincomplete revascularization.


Instruction: What type of ischemia are patients with SIHD at high risk for a recurrent cardiac event at risk for?

Output: silent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of ischemia are patients with SIHD at high risk for a recurrent cardiac event at risk for?. ### Response: silent.


Instruction: What is the level of evidence for SIHD?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for SIHD?. ### Response: C.


Instruction: What type of ECG testing is not well established in patients with no new or worsening symptoms?

Output: annual surveillance exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of ECG testing is not well established in patients with no new or worsening symptoms?. ### Response: annual surveillance exercise.


Instruction: Nuclear MPI, echocardiography, and electrocardiography are examples of what?

Output: Class IIa1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nuclear MPI, echocardiography, and electrocardiography are examples of what?. ### Response: Class IIa1.


Instruction: What is not recommended for follow-up assessment in patients with SIHD if performed more frequently than a) 5-year intervals after CABG or b) 2-yearintervals after PCI?

Output: Nuclear MPI, echocardiography, or CMR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for follow-up assessment in patients with SIHD if performed more frequently than a) 5-year intervals after CABG or b) 2-yearintervals after PCI?. ### Response: Nuclear MPI, echocardiography, or CMR.


Instruction: What is the Level of Evidence: C )Class III: No Benefit1?

Output: annual surveillance exercise ECG testing isnot well established

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence: C )Class III: No Benefit1?. ### Response: annual surveillance exercise ECG testing isnot well established.


Instruction: How long after PCI is there a 2-year interval?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after PCI is there a 2-year interval?. ### Response: 5-year.


Instruction: What is the level of evidence for noninvasive testing in known SIHD?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for noninvasive testing in known SIHD?. ### Response: C.


Instruction: How does the appropriateness of performing noninvasive testing inpatients depend on?

Output: factorsrelated to the likelihood of significant findings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the appropriateness of performing noninvasive testing inpatients depend on?. ### Response: factorsrelated to the likelihood of significant findings.


Instruction: What is asymptomatic or have stable symp-toms?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic or have stable symp-toms?. ### Response: patients.


Instruction: What depends on factors related to the likelihood of significant findings?

Output: The appropriateness of performing noninvasive testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What depends on factors related to the likelihood of significant findings?. ### Response: The appropriateness of performing noninvasive testing.


Instruction: The data supporting follow-up testing are sparse and insufficient to support what?

Output: routine, repeat testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The data supporting follow-up testing are sparse and insufficient to support what?. ### Response: routine, repeat testing.


Instruction: What is insufficient to support routine, repeat testing in asymptomatic individuals?

Output: The data supporting follow-up testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is insufficient to support routine, repeat testing in asymptomatic individuals?. ### Response: The data supporting follow-up testing.


Instruction: Evidence exists that persistent ische-mia on testing is a prognostically poor finding?

Output: encing the Use of Follow-Up Testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence exists that persistent ische-mia on testing is a prognostically poor finding?. ### Response: encing the Use of Follow-Up Testing.


Instruction: How many patients with SIHD were enrolled in the COURAGE trial nuclear substudy?

Output: 314

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with SIHD were enrolled in the COURAGE trial nuclear substudy?. ### Response: 314.


Instruction: What isduction in the ischemic myocardium associated with?

Output: reduction in the incidence of death or MIcombined

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isduction in the ischemic myocardium associated with?. ### Response: reduction in the incidence of death or MIcombined.


Instruction: What is unadjusted reduction in the incidence of death or MI combined?

Output: 306

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unadjusted reduction in the incidence of death or MI combined?. ### Response: 306.


Instruction: In the BARI 2D trial, at 1 year of follow-up, what were associated with higher rates ofdeath or MI?

Output: more extensive and severe stress myocardial perfusionSPECT abnormalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the BARI 2D trial, at 1 year of follow-up, what were associated with higher rates ofdeath or MI?. ### Response: more extensive and severe stress myocardial perfusionSPECT abnormalities.


Instruction: What are some circumstances in which a decision to perform follow-up testing is thought to bewarranted in the absence of a change in clinical status?

Output: evaluation ofincomplete revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some circumstances in which a decision to perform follow-up testing is thought to bewarranted in the absence of a change in clinical status?. ### Response: evaluation ofincomplete revascularization.


Instruction: Evaluation of incomplete revascularization, assessment of the adequacy of what?

Output: follow-up testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evaluation of incomplete revascularization, assessment of the adequacy of what?. ### Response: follow-up testing.


Instruction: What are the long-term results of cuspid aortic valve replacement?

Output: Two decades

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the long-term results of cuspid aortic valve replacement?. ### Response: Two decades.


Instruction: What is the name of the valve that should be replaced more frequently in patients with bicuspid valve disease?

Output: ascending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the valve that should be replaced more frequently in patients with bicuspid valve disease?. ### Response: ascending aorta.


Instruction: What type of valve surgery is associated with a pro-active ascending aorta repair?

Output: Bicuspid aortic valve sur -gery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve surgery is associated with a pro-active ascending aorta repair?. ### Response: Bicuspid aortic valve sur -gery.


Instruction: What year did J Thorac Cardiovasc Surg publish 142:622-9, 9.9.e1–3?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Thorac Cardiovasc Surg publish 142:622-9, 9.9.e1–3?. ### Response: 2011.


Instruction: Beckerman Z, Kayatta MO, McPherson L, et al. found a bicuspid valve repair in the setting of severe what?

Output: aortic insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beckerman Z, Kayatta MO, McPherson L, et al. found a bicuspid valve repair in the setting of severe what?. ### Response: aortic insufficiency.


Instruction: J Vis Surg. 2018;4:101

Output: Bicuspid aortic valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Vis Surg. 2018;4:101. ### Response: Bicuspid aortic valve repair.


Instruction: What year did J Vis Surg. 2018:4:101?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Vis Surg. 2018:4:101?. ### Response: 2011.


Instruction: How long did David TE, Feindel CM, David C, et al. experince with aortic valve-sparing operations?

Output: A quarter of a century

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did David TE, Feindel CM, David C, et al. experince with aortic valve-sparing operations?. ### Response: A quarter of a century.


Instruction: When did Davies RR, Kaple RK, Mandapati D, and others have a natural history of ascending aneurysms?

Output: in the setting of an unreplaced bicuspid aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Davies RR, Kaple RK, Mandapati D, and others have a natural history of ascending aneurysms?. ### Response: in the setting of an unreplaced bicuspid aortic valve.


Instruction: What is a natural history of?

Output: ascending aortic aneurysms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a natural history of?. ### Response: ascending aortic aneurysms.


Instruction: What is the setting of an unreplaced bicuspid aortic valve?

Output: Natural history of ascending aortic aneurysms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the setting of an unreplaced bicuspid aortic valve?. ### Response: Natural history of ascending aortic aneurysms.


Instruction: When did Ergin MA, Spielvogel D, Apaydin A, et al. surgical treatment of the dilated ascending Aorta: when and how?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ergin MA, Spielvogel D, Apaydin A, et al. surgical treatment of the dilated ascending Aorta: when and how?. ### Response: 11.


Instruction: Ann Thorac Surg. 1999;67:1834–9. 12. Svensson LG, Kim K-H, Lytle BW, et al. Relationship of aortic cross-sec-tional area to height ratio and the risk of dissection in patients with what type of valves?

Output: bicuspid aortic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ann Thorac Surg. 1999;67:1834–9. 12. Svensson LG, Kim K-H, Lytle BW, et al. Relationship of aortic cross-sec-tional area to height ratio and the risk of dissection in patients with what type of valves?. ### Response: bicuspid aortic valves.


Instruction: What type of valve is used to prevent progressive dilation of ascending aorta?

Output: aortic valve replacement in patients with bicuspid aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve is used to prevent progressive dilation of ascending aorta?. ### Response: aortic valve replacement in patients with bicuspid aortic valve.


Instruction: What is the difference between tricuspid and bicuspid valves?

Output: transcatheter aortic valve implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between tricuspid and bicuspid valves?. ### Response: transcatheter aortic valve implantation.


Instruction: In what year did Circulation issue 108(suppl 1):II291–4?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Circulation issue 108(suppl 1):II291–4?. ### Response: 2003.


Instruction: What is Fate of nonreplaced sinuses of Valsalva in bicuspid aortic valve disease?

Output: 14. Park CB, Greason KL, Suri RM, et al. Fate of nonreplaced sinuses of Valsalva in bicuspid aortic valve disease. J Thorac Cardiovasc Surg. 2011;142:278–84

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Fate of nonreplaced sinuses of Valsalva in bicuspid aortic valve disease?. ### Response: 14. Park CB, Greason KL, Suri RM, et al. Fate of nonreplaced sinuses of Valsalva in bicuspid aortic valve disease. J Thorac Cardiovasc Surg. 2011;142:278–84.


Instruction: What is the J Thorac Cardiovasc Surg. 2011;142:278–84.

Output: Fate of nonreplaced sinuses of Valsalva in bicuspid aortic valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Thorac Cardiovasc Surg. 2011;142:278–84.. ### Response: Fate of nonreplaced sinuses of Valsalva in bicuspid aortic valve disease.


Instruction: What are the guidelines for management and quality measures?

Output: Aortic valve and ascending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the guidelines for management and quality measures?. ### Response: Aortic valve and ascending aorta.


Instruction: What is the name of the aortic valve that is repaired or replaced?

Output: bicuspid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the aortic valve that is repaired or replaced?. ### Response: bicuspid.


Instruction: How long has David TE, Feindel CM, David CM been doing?

Output: quarter of a century

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has David TE, Feindel CM, David CM been doing?. ### Response: quarter of a century.


Instruction: What does J Thorac Cardiovasc Surg. 2014:148:872–9?

Output: aortic valve-sparing operations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does J Thorac Cardiovasc Surg. 2014:148:872–9?. ### Response: aortic valve-sparing operations.


Instruction: What are the characteristics of contemporary patients with bicuspid aortic valves?

Output: long-term outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the characteristics of contemporary patients with bicuspid aortic valves?. ### Response: long-term outcomes.


Instruction: How long has Schneider U, Feldner SK, Hofmann C, et al. had experience with root remodeling and valve repair?

Output: Two decades

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has Schneider U, Feldner SK, Hofmann C, et al. had experience with root remodeling and valve repair?. ### Response: Two decades.


Instruction: What is Takagi's name?

Output: Nakatani S

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Takagi's name?. ### Response: Nakatani S.


Instruction: What type of aortic valves are used?

Output: bicuspid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of aortic valves are used?. ### Response: bicuspid.


Instruction: What is the name of the study that compares bicuspid versus tricuspid valves?

Output: Meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares bicuspid versus tricuspid valves?. ### Response: Meta-analysis.


Instruction: When was the last time a patient had a transcatheter valve replacement?

Output: A quarter of a century

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a patient had a transcatheter valve replacement?. ### Response: A quarter of a century.


Instruction: What is the name of the systematic review and meta-analysis that compares outcomes after transcatheter aortic valve replacement in patients with stenotic bi-cuspid and tricuspid?

Output: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis that compares outcomes after transcatheter aortic valve replacement in patients with stenotic bi-cuspid and tricuspid?. ### Response: a systematic review and meta-analysis.


Instruction: What does Makkar RR, Yoon S-H, Leon MB, et al. have an association between?

Output: transcatheter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Makkar RR, Yoon S-H, Leon MB, et al. have an association between?. ### Response: transcatheter.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 6 of 127

Output: This document is an update to the 20 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 6 of 127. ### Response: This document is an update to the 20 14.


Instruction: What is the principal driver for the management of lipids in the primary prevention of CVD?

Output: CVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the principal driver for the management of lipids in the primary prevention of CVD?. ### Response: CVD risk.


Instruction: What is FH?

Output: familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is FH?. ### Response: familial hypercholesterolemia.


Instruction: How many mg/dL of TGs are in patients with CVD or elevated risk for CVD?

Output: ≥200

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg/dL of TGs are in patients with CVD or elevated risk for CVD?. ### Response: ≥200.


Instruction: What is the definition of low-density lipoprotein cholesterol?

Output: ≥130 milligram s per deciliter (mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of low-density lipoprotein cholesterol?. ### Response: ≥130 milligram s per deciliter (mg/dL.


Instruction: What does the treatment of dyslipidemia involve?

Output: lifestyle changes and lipid -lowering drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the treatment of dyslipidemia involve?. ### Response: lifestyle changes and lipid -lowering drugs.


Instruction: What has shifted from treating dyslipidemic as a discrete entity?

Output: the management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has shifted from treating dyslipidemic as a discrete entity?. ### Response: the management.


Instruction: What did the CPG address in the context of overall risk for CVD?

Output: lipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the CPG address in the context of overall risk for CVD?. ### Response: lipidemia.


Instruction: What does much of our evidence base on?

Output: CV  risk reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does much of our evidence base on?. ### Response: CV  risk reduction.


Instruction: What does this guideline address?

Output: various treatment and management strategies for managing lipids among patients at risk for CVD morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does this guideline address?. ### Response: various treatment and management strategies for managing lipids among patients at risk for CVD morbidity and mortality.


Instruction: What does the guideline aim to efficiently improve for patients with CVD?

Output: dyslipidemia management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the guideline aim to efficiently improve for patients with CVD?. ### Response: dyslipidemia management.


Instruction: What is the goal of this guideline?

Output: efficiently improving dyslipidemia management for CV risk reduction in the VA and DoD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of this guideline?. ### Response: efficiently improving dyslipidemia management for CV risk reduction in the VA and DoD.


Instruction: Who is intended to use this CPG?

Output: all VA and DoD  healthcare providers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is intended to use this CPG?. ### Response: all VA and DoD  healthcare providers.


Instruction: What is not intended to serve as a standard of care?

Output: Clinical Practice Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not intended to serve as a standard of care?. ### Response: Clinical Practice Guideline.


Instruction: What are standards of care determined on the basis of all clinical data available for an individual patient?

Output: Clinical Practice Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are standards of care determined on the basis of all clinical data available for an individual patient?. ### Response: Clinical Practice Guideline.


Instruction: What is subject to change as scientific knowledge and technology advance and patterns evolve?

Output: Standards of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is subject to change as scientific knowledge and technology advance and patterns evolve?. ### Response: Standards of care.


Instruction: What is the purpose of the guideline?

Output: efficiently improving dyslipidemia management for CV risk reduction in the VA and DoD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of the guideline?. ### Response: efficiently improving dyslipidemia management for CV risk reduction in the VA and DoD.


Instruction: What must be included in a CPG’s content?

Output: a recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be included in a CPG’s content?. ### Response: a recommendation.


Instruction: What can guideline help?

Output: providers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can guideline help?. ### Response: providers.


Instruction: What must always be considered as a recommendation within the context of a provider's clinical judgment and patient values and preferences?

Output: CPG’s content

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must always be considered as a recommendation within the context of a provider's clinical judgment and patient values and preferences?. ### Response: CPG’s content.


Instruction: The evolution of medical practice and future scientific rese arch will likely impact what?

Output: these recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The evolution of medical practice and future scientific rese arch will likely impact what?. ### Response: these recommendations.


Instruction: What did the Work Group determine after assessing the currently available evidence?

Output: future research topics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group determine after assessing the currently available evidence?. ### Response: future research topics.


Instruction: What are the abbreviated provider summary, patient summary, and p ocket card available at?

Output: https://www.healthquality.va.gov/guidelines/CD/lipids/ .

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the abbreviated provider summary, patient summary, and p ocket card available at?. ### Response: https://www.healthquality.va.gov/guidelines/CD/lipids/ ..


Instruction: How many VA/DoD Dyslipidemia CPGs are there?

Output: 20 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many VA/DoD Dyslipidemia CPGs are there?. ### Response: 20 14.


Instruction: What is CHEST / 141/ 2/ FEBRUARY, 2012 SUPPLEMENT e37S 31?

Output: chestpubs.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CHEST / 141/ 2/ FEBRUARY, 2012 SUPPLEMENT e37S 31?. ### Response: chestpubs.org.


Instruction: Shaughnessy SG, Young E, Deschamps P, Hirsh J.

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Shaughnessy SG, Young E, Deschamps P, Hirsh J.. ### Response: 2012.


Instruction: Low molecular weight and standard heparin on cal-cium loss from fetal rat calvaria?

Output: xed-dose weight-adjusted unfractionated heparin and low-molecular-weight heparin for acute treatment of venous thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Low molecular weight and standard heparin on cal-cium loss from fetal rat calvaria?. ### Response: xed-dose weight-adjusted unfractionated heparin and low-molecular-weight heparin for acute treatment of venous thromboembolism.


Instruction: Blood. 1995 ; 86 ( 4 ): 1368 - 1373.

Output: Blood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood. 1995 ; 86 ( 4 ): 1368 - 1373.. ### Response: Blood.


Instruction: Linkins L-A, Dans AL, Moores LK, et al.

Output: 32

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Linkins L-A, Dans AL, Moores LK, et al.. ### Response: 32.


Instruction: What is heparin-induced thrombocytopenia treated with?

Output: antithrom-botic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heparin-induced thrombocytopenia treated with?. ### Response: antithrom-botic therapy.


Instruction: What is the 9th ed of the American College of Chest Physicians evidence-based clinical practice guidelines?

Output: Treatment and pre-vention of heparin-induced thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 9th ed of the American College of Chest Physicians evidence-based clinical practice guidelines?. ### Response: Treatment and pre-vention of heparin-induced thrombocytopenia.


Instruction: What was Berkowitz SD's title?

Output: Orthopedics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was Berkowitz SD's title?. ### Response: Orthopedics.


Instruction: What is the name of the armamentarium used for deep vein thrombosis?

Output: therapeutic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the armamentarium used for deep vein thrombosis?. ### Response: therapeutic.


Instruction: When was Orthopedics published?

Output: 1995

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Orthopedics published?. ### Response: 1995.


Instruction: Subcutaneous vs intravenous heparin in the treatment of deep vein thrombosis—a randomized clinical trial?

Output: intra-venous and subcutaneous administration .   Thromb Res  .   1985 ; 39 ( 5 ): 631 - 636 .      37 .  Powers   PJ ,  Gent   M ,  Jay   RM ,  et al .  A randomized trial of less intense postoperative warfarin or aspirin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Subcutaneous vs intravenous heparin in the treatment of deep vein thrombosis—a randomized clinical trial?. ### Response: intra-venous and subcutaneous administration .   Thromb Res  .   1985 ; 39 ( 5 ): 631 - 636 .      37 .  Powers   PJ ,  Gent   M ,  Jay   RM ,  et al .  A randomized trial of less intense postoperative warfarin or aspirin therapy.


Instruction: Deep venous thrombosis—a randomized clinical trial?

Output: Subcutaneous vs intravenous heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Deep venous thrombosis—a randomized clinical trial?. ### Response: Subcutaneous vs intravenous heparin.


Instruction: How many ( 2 ): 222 - 226 were in Thromb Haemost in 1990?

Output: 64

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 2 ): 222 - 226 were in Thromb Haemost in 1990?. ### Response: 64.


Instruction: What is Fixed-Dose Heparin?

Output: FIDO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Fixed-Dose Heparin?. ### Response: FIDO.


Instruction: What is the difference between fi xed-dose and low-molecular-weight heparin for acute treatment of venous thromboembolism?

Output: weight-adjusted unfractionated heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between fi xed-dose and low-molecular-weight heparin for acute treatment of venous thromboembolism?. ### Response: weight-adjusted unfractionated heparin.


Instruction: When did JAMA issue 296?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 296?. ### Response: 2006.


Instruction: What year was JAMA published?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was JAMA published?. ### Response: 2006.


Instruction: How many pages were in JAMA in 2006?

Output: 296 ( 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages were in JAMA in 2006?. ### Response: 296 ( 8.


Instruction: What is the molecular weight of heparin?

Output: PK 10 169

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the molecular weight of heparin?. ### Response: PK 10 169.


Instruction: What are the PK 10 169 and unfractionated?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the PK 10 169 and unfractionated?. ### Response: heparin.


Instruction: When was Thromb Res published?

Output: 1985

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Thromb Res published?. ### Response: 1985.


Instruction: What is the name of the randomized trial of less intense postoperative warfarin?

Output: aspirin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of less intense postoperative warfarin?. ### Response: aspirin therapy.


Instruction: What was a randomized trial of less intense postoperative warfarin or aspirin therapy in the prevention of after surgery for fractured hip?

Output: venous thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a randomized trial of less intense postoperative warfarin or aspirin therapy in the prevention of after surgery for fractured hip?. ### Response: venous thromboembolism.


Instruction: What was the name of the randomized study?

Output: Thromb Haemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the randomized study?. ### Response: Thromb Haemost.


Instruction: When was the 149 ( 4 ): 771- 774 published?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 149 ( 4 ): 771- 774 published?. ### Response: 1989.


Instruction: How many. 38?

Output: 379

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many. 38?. ### Response: 379.


Instruction: What is heparin kinetics in?

Output: venous thrombosis and pul-monary embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heparin kinetics in?. ### Response: venous thrombosis and pul-monary embolism.


Instruction: Who is Yung WL?

Output: Heparin kinetics in venous thrombosis and pul-monary embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Yung WL?. ### Response: Heparin kinetics in venous thrombosis and pul-monary embolism.


Instruction: What is heparin kinetics in in venous thrombosis and pulmonary embolism?

Output: weight-adjusted unfractionated heparin and low-molecular-weight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heparin kinetics in in venous thrombosis and pulmonary embolism?. ### Response: weight-adjusted unfractionated heparin and low-molecular-weight.


Instruction: What is Brey RL's specialty?

Output: Antiphospholipid antibodies and ischemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Brey RL's specialty?. ### Response: Antiphospholipid antibodies and ischemic stroke.


Instruction: Antiphospholipid antibodies and ischemic stroke. 1992 ; 1 ( 6 ): 379 - 382.

Output: Heart Dis Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antiphospholipid antibodies and ischemic stroke. 1992 ; 1 ( 6 ): 379 - 382.. ### Response: Heart Dis Stroke.


Instruction: Bârzu T, Molho P, et al.

Output: 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bârzu T, Molho P, et al.. ### Response: 40.


Instruction: What is binding and endocytosis of heparin by human endothelial cells in culture?

Output: Kinetics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is binding and endocytosis of heparin by human endothelial cells in culture?. ### Response: Kinetics.


Instruction: What year was Biochim Biophys Acta published?

Output: 1985

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Biochim Biophys Acta published?. ### Response: 1985.


Instruction: How many ( 2 ): 196 - 203?

Output: 845

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 2 ): 196 - 203?. ### Response: 845.


Instruction: Who inhibited von Willebrand factor-dependent platelet function in vitro and in vivo?

Output: Heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who inhibited von Willebrand factor-dependent platelet function in vitro and in vivo?. ### Response: Heparin.


Instruction: When did J Clin Invest publish 87 ( 5 ): 1787 - 1793?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Clin Invest publish 87 ( 5 ): 1787 - 1793?. ### Response: 1991.


Instruction: How many assay methods did Bjornsson TD, Wolfram KM, Kitchell BB use to determine heparin kinetics?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many assay methods did Bjornsson TD, Wolfram KM, Kitchell BB use to determine heparin kinetics?. ### Response: three.


Instruction: What year did Clin Pharmacol Ther issue 31 ( 1 ): 104?

Output: 1982

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Clin Pharmacol Ther issue 31 ( 1 ): 104?. ### Response: 1982.


Instruction: What was the average number of intravenously administered antibiotics in 1982?

Output: 104 - 113

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the average number of intravenously administered antibiotics in 1982?. ### Response: 104 - 113.


Instruction: What is the average amount of intravenous antibiotics used in 1982 in the United States?

Output: 1251 - 1258

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average amount of intravenous antibiotics used in 1982 in the United States?. ### Response: 1251 - 1258.


Instruction: In 1982, what percentage of the population was given antibiotics?

Output: 104 - 113

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 1982, what percentage of the population was given antibiotics?. ### Response: 104 - 113.


Instruction: What is the name of the drug that is administered intravenously in humans?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is administered intravenously in humans?. ### Response: heparin.


Instruction: How many blood samples were collected in 1982?

Output: 1251 - 1258

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many blood samples were collected in 1982?. ### Response: 1251 - 1258.


Instruction: What was the total number of blood samples collected from 1982-82?

Output: 1251 - 1258

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the total number of blood samples collected from 1982-82?. ### Response: 1251 - 1258.


Instruction: What is valsartan used for in patients with type 2 diabetes?

Output: urinary albumin excretion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is valsartan used for in patients with type 2 diabetes?. ### Response: urinary albumin excretion.


Instruction: What is the effect of intensive blood pressure control on urinary albumin excretion?

Output: type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of intensive blood pressure control on urinary albumin excretion?. ### Response: type 2 diabetes.


Instruction: What does intensive blood pressure control have on the course of type 1 diabetic nephropathy?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does intensive blood pressure control have on the course of type 1 diabetic nephropathy?. ### Response: Effect.


Instruction: What did Collaborative StudyGroup do?

Output: Effect of intensive blood pressure controlon the course of type 1 diabetic nephropathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Collaborative StudyGroup do?. ### Response: Effect of intensive blood pressure controlon the course of type 1 diabetic nephropathy.


Instruction: When did Am J Kidney Dis issue 34:809-817.49?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Am J Kidney Dis issue 34:809-817.49?. ### Response: 2007.


Instruction: What is the name of the Systolic Blood PressureIntervention Trial?

Output: SPRINT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Systolic Blood PressureIntervention Trial?. ### Response: SPRINT.


Instruction: What is SPRINT?

Output: Systolic Blood PressureIntervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SPRINT?. ### Response: Systolic Blood PressureIntervention Trial.


Instruction: How is the glomerular filtration rate estimated?

Output: a post hoc analysis of a randomizedclinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the glomerular filtration rate estimated?. ### Response: a post hoc analysis of a randomizedclinical trial.


Instruction: Shintani A, et al. Estimated glomerular filtrationrate and the risk-benefit pro file of intensive blood pressure control among nondiabetic patients: a post hoc analysis of a randomizedclinical trial.

Output: ﬁ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Shintani A, et al. Estimated glomerular filtrationrate and the risk-benefit pro file of intensive blood pressure control among nondiabetic patients: a post hoc analysis of a randomizedclinical trial.. ### Response: ﬁ.


Instruction: Nguyen LS. Effect of additional antihypertensive medications in patientswith high-risk hypertension: elaboration of what?

Output: instrumental variable analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nguyen LS. Effect of additional antihypertensive medications in patientswith high-risk hypertension: elaboration of what?. ### Response: instrumental variable analysis.


Instruction: What is the acronym for SystolicBlood Pressure Intervention Trial?

Output: SPRINT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for SystolicBlood Pressure Intervention Trial?. ### Response: SPRINT.


Instruction: What does SPRINT stand for?

Output: SystolicBlood Pressure Intervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SPRINT stand for?. ### Response: SystolicBlood Pressure Intervention Trial.


Instruction: When was the J Clin Hypertens(Greenwich) published?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Clin Hypertens(Greenwich) published?. ### Response: 2018.


Instruction: What is the cost-effectiveness of intensive versus standard blood-pressure control?

Output: Estimated glomerular ﬁltrationrate and the risk-bene ﬁt pro ﬁle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of intensive versus standard blood-pressure control?. ### Response: Estimated glomerular ﬁltrationrate and the risk-bene ﬁt pro ﬁle.


Instruction: What was the N Engl J Med 2017:377:745-755?

Output: Cost-effectiveness of intensive versusstandard blood-pressure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med 2017:377:745-755?. ### Response: Cost-effectiveness of intensive versusstandard blood-pressure control.


Instruction: What is the name of the NICE guideline for hypertension in adults?

Output: NG136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the NICE guideline for hypertension in adults?. ### Response: NG136.


Instruction: When was the Am J KidneyDis published?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J KidneyDis published?. ### Response: 2005.


Instruction: What is the name of the NICE guideline for adults?

Output: NG136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the NICE guideline for adults?. ### Response: NG136.


Instruction: When was NICE's 2018guidelines for diagnosis, risk assessment, prevention, and treatment of hypertension in adults and children released?

Output: January 15,2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was NICE's 2018guidelines for diagnosis, risk assessment, prevention, and treatment of hypertension in adults and children released?. ### Response: January 15,2021.


Instruction: What are the 2018 guidelines for the management of resistanthypertension from Hypertension Canada?

Output: diagnosis, risk assessment, prevention, and treatment ofhypertension in adults and children

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2018 guidelines for the management of resistanthypertension from Hypertension Canada?. ### Response: diagnosis, risk assessment, prevention, and treatment ofhypertension in adults and children.


Instruction: What is the 2018 criteria for ambulatory andhome blood pressure monitoring?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 criteria for ambulatory andhome blood pressure monitoring?. ### Response: 2019.


Instruction: What is the 2017 AmericanCollege of Cardiology/American Heart Association Guideline?

Output: Rationale for ambulatory andhome blood pressure monitoring thresholds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 AmericanCollege of Cardiology/American Heart Association Guideline?. ### Response: Rationale for ambulatory andhome blood pressure monitoring thresholds.


Instruction: What are the ambulatory and home blood pressure monitoring thresholds?

Output: 2017 AmericanCollege of Cardiology/American Heart Association Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the ambulatory and home blood pressure monitoring thresholds?. ### Response: 2017 AmericanCollege of Cardiology/American Heart Association Guideline.


Instruction: How are renal outcomes in high-riskhypertensive patients treated?

Output: with an angiotensin-converting enzyme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are renal outcomes in high-riskhypertensive patients treated?. ### Response: with an angiotensin-converting enzyme.


Instruction: How many hospitalisations were there?

Output: 198

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hospitalisations were there?. ### Response: 198.


Instruction: What did not show a clear effect?

Output: Mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not show a clear effect?. ### Response: Mortality.


Instruction: What was rated as very low quality for the comparison of BBs versus placebo?

Output: the majority of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as very low quality for the comparison of BBs versus placebo?. ### Response: the majority of the evidence.


Instruction: What did the outcome all -cause mortality suggest?

Output: a clinically important reduction in deaths

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the outcome all -cause mortality suggest?. ### Response: a clinically important reduction in deaths.


Instruction: How many deaths were there for CKD class 3a?

Output: 1645

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths were there for CKD class 3a?. ### Response: 1645.


Instruction: What was the reduction in deaths for BBs?

Output: decrease and increase in all -cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in deaths for BBs?. ### Response: decrease and increase in all -cause mortality.


Instruction: How many people were hospitalized for the composite outcome of death?

Output: 669

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were hospitalized for the composite outcome of death?. ### Response: 669.


Instruction: What was the clinically important reduction in HF hospitalisations for CKD class 3a?

Output: n=669

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the clinically important reduction in HF hospitalisations for CKD class 3a?. ### Response: n=669.


Instruction: What did there be no clinical effect of for the outcomes bradycardia and hypotension?

Output: BBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did there be no clinical effect of for the outcomes bradycardia and hypotension?. ### Response: BBs.


Instruction: What did not show a clinical effect of BBs?

Output: bradycardia and hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not show a clinical effect of BBs?. ### Response: bradycardia and hypotension.


Instruction: What was the confidence interval ranging from a dec rease and increase in all-cause mortality?

Output: decrease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the confidence interval ranging from a dec rease and increase in all-cause mortality?. ### Response: decrease.


Instruction: What was the majority of the evidence for the comparison of digoxin versus placebo rated as?

Output: very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the majority of the evidence for the comparison of digoxin versus placebo rated as?. ### Response: very low quality.


Instruction: What type of mortality was not demonstrated in CKD class 3a -b?

Output: all -cause

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of mortality was not demonstrated in CKD class 3a -b?. ### Response: all -cause.


Instruction: What did the confidence interval range from a decrease and increase in all-cause mortality?

Output: Mortality (n=792) did not demonstrate a clear effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the confidence interval range from a decrease and increase in all-cause mortality?. ### Response: Mortality (n=792) did not demonstrate a clear effect.


Instruction: What was also the case for the composite outcome of death or hospitalisation?

Output: CKD class 3b -4 (n=958) with BBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was also the case for the composite outcome of death or hospitalisation?. ### Response: CKD class 3b -4 (n=958) with BBs.


Instruction: What drug was used to treat hyperkalaemia?

Output: Ivabradine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was used to treat hyperkalaemia?. ### Response: Ivabradine.


Instruction: What was the quality of the evidence for the use of ivabradine versus placebo?

Output: low to very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence for the use of ivabradine versus placebo?. ### Response: low to very low quality.


Instruction: How many people were compared to the placebo group for renal function?

Output: n=865

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were compared to the placebo group for renal function?. ### Response: n=865.


Instruction: Who was the only person who was not affected by renal failure?

Output: 1579

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the only person who was not affected by renal failure?. ### Response: 1579.


Instruction: How many people had symptomatic bradyca rdia?

Output: n=1579

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people had symptomatic bradyca rdia?. ### Response: n=1579.


Instruction: What did the evidence range from for the comparison of MRA versus placebo?

Output: low to very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the evidence range from for the comparison of MRA versus placebo?. ### Response: low to very low quality.


Instruction: How many hospitalisations suggested a clinical important reduction with MRAs?

Output: n=792

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hospitalisations suggested a clinical important reduction with MRAs?. ### Response: n=792.


Instruction: The combined outcome of cardiovascu lar mortality and HF admission was what?

Output: n=912

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The combined outcome of cardiovascu lar mortality and HF admission was what?. ### Response: n=912.


Instruction: What was the combined outcome of cardiovascular mortality and HF admission?

Output: n=912

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the combined outcome of cardiovascular mortality and HF admission?. ### Response: n=912.


Instruction: What did the evidence suggest for the outcome hyperkalemia?

Output: a clinically important increase with MRAs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the evidence suggest for the outcome hyperkalemia?. ### Response: a clinically important increase with MRAs.


Instruction: Which outcome did not demonstrate a clear effect?

Output: Mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which outcome did not demonstrate a clear effect?. ### Response: Mortality.


Instruction: What were no relevant economic evaluations identified?

Output: Economic   No relevant economic evaluations were identified.  6.2.6.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were no relevant economic evaluations identified?. ### Response: Economic   No relevant economic evaluations were identified.  6.2.6.6.


Instruction: What is the eGFR of a person with heart failure with reduced ejection fraction and chronic kidney disease?

Output: 30ml/min/1. 73 m2 or above

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the eGFR of a person with heart failure with reduced ejection fraction and chronic kidney disease?. ### Response: 30ml/min/1. 73 m2 or above.


Instruction: If the person has heart failure and kidney disease, what should they do?

Output: Offer the treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the person has heart failure and kidney disease, what should they do?. ### Response: Offer the treatment.


Instruction: What should the person do if their heart failure has an egFR of 45ml/min/1.73 m2 or below?

Output: consider lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the person do if their heart failure has an egFR of 45ml/min/1.73 m2 or below?. ### Response: consider lower.


Instruction: What are options for SAVR and mitral valve surgery?

Output: a staged approach with TAVI followed by mitral TEER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are options for SAVR and mitral valve surgery?. ### Response: a staged approach with TAVI followed by mitral TEER.


Instruction: What is a staged approach with TAVI followed by mitral TEER?

Output: SAVR and mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a staged approach with TAVI followed by mitral TEER?. ### Response: SAVR and mitral valve surgery.


Instruction: Why has the writ-ing committee created a table?

Output: there are limited data to support COR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why has the writ-ing committee created a table?. ### Response: there are limited data to support COR.


Instruction: What are the possible interventions in AS complex patients?

Output: SAVR and mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the possible interventions in AS complex patients?. ### Response: SAVR and mitral valve surgery.


Instruction: What will be important to evaluate the short- and long-term outcomes of these approaches?

Output: SAVR and mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will be important to evaluate the short- and long-term outcomes of these approaches?. ### Response: SAVR and mitral valve surgery.


Instruction: AVR for AS reduces what?

Output: LV pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AVR for AS reduces what?. ### Response: LV pressure.


Instruction: What does AVR reduce that propels volume across the incompetent mitral valve?

Output: LV pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AVR reduce that propels volume across the incompetent mitral valve?. ### Response: LV pressure.


Instruction: Why is primary MR more likely to persist after AVR than is secondary MR?

Output: AVR does not correct intrinsic mitral valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is primary MR more likely to persist after AVR than is secondary MR?. ### Response: AVR does not correct intrinsic mitral valve disease.


Instruction: What does not correct intrinsic mitral valve disease?

Output: AVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not correct intrinsic mitral valve disease?. ### Response: AVR.


Instruction: What is reasonable to address both valves with surgery?

Output: in patients with both AS and MR who are at a low or intermediate surgical risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to address both valves with surgery?. ### Response: in patients with both AS and MR who are at a low or intermediate surgical risk.


Instruction: What is particularly true if the mitral valve can be repaired?

Output: it is reasonable to address both valves with surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is particularly true if the mitral valve can be repaired?. ### Response: it is reasonable to address both valves with surgery.


Instruction: For patients with AS and severe primary MR, what is reasonable?

Output: address both valves with surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients with AS and severe primary MR, what is reasonable?. ### Response: address both valves with surgery.


Instruction: What will need to be made about treatment of the MR by the MDT?

Output: a deci-sion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will need to be made about treatment of the MR by the MDT?. ### Response: a deci-sion.


Instruction: What factors are taken into consideration?

Output: mul-tiple factors, including the additive risk of a mitral valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What factors are taken into consideration?. ### Response: mul-tiple factors, including the additive risk of a mitral valve replacement.


Instruction: At a later date what may be an option but is likely not?

Output: Mitral TEER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At a later date what may be an option but is likely not?. ### Response: Mitral TEER.


Instruction: What may be an option but is likely to have a suboptimal result if the valve cannot be surgically repaired?

Output: Mitral TEER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be an option but is likely to have a suboptimal result if the valve cannot be surgically repaired?. ### Response: Mitral TEER.


Instruction: Double valve replacement with both AVR and mitral valve replacement would be what if they can be performed at an acceptable level of risk?

Output: an option

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Double valve replacement with both AVR and mitral valve replacement would be what if they can be performed at an acceptable level of risk?. ### Response: an option.


Instruction: What type of patient is best served by TAVI?

Output: Patients with severe AS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patient is best served by TAVI?. ### Response: Patients with severe AS.


Instruction: What may not improve after AVR?

Output: primary MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not improve after AVR?. ### Response: primary MR.


Instruction: What can be performed if symptoms persist after TAVI and if there is suitable anatomy?

Output: percutaneous mitral repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be performed if symptoms persist after TAVI and if there is suitable anatomy?. ### Response: percutaneous mitral repair.


Instruction: Percutaneous mitral repair can reduce MR and improve what?

Output: symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Percutaneous mitral repair can reduce MR and improve what?. ### Response: symptoms.


Instruction: What is more likely to improve after AVR than MR attributable to primary mitral valve disease?

Output: secondary MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more likely to improve after AVR than MR attributable to primary mitral valve disease?. ### Response: secondary MR.


Instruction: What is the mechanism by which reduction in LV pressure after aVR is mediated?

Output: reducing the pressure gradi-ent that propels volume across the incompetent mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mechanism by which reduction in LV pressure after aVR is mediated?. ### Response: reducing the pressure gradi-ent that propels volume across the incompetent mitral valve.


Instruction: What is the mechanism by which reduction in LV pressure after?

Output: AVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mechanism by which reduction in LV pressure after?. ### Response: AVR.


Instruction: When was this article published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 28, 2023.


Instruction: How many antihypertensive agents are available for the treatment of hyperten-sive emergencies?

Output: Several

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many antihypertensive agents are available for the treatment of hyperten-sive emergencies?. ### Response: Several.


Instruction: How many strategies to improve hypertension treatment and control are available?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strategies to improve hypertension treatment and control are available?. ### Response: 12.


Instruction: What can play an important role in promoting pharmacological and nonpharmaco-logical treatment adherence in individual patients with hyper -tension?

Output: population-based systems approaches

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can play an important role in promoting pharmacological and nonpharmaco-logical treatment adherence in individual patients with hyper -tension?. ### Response: population-based systems approaches.


Instruction: What is therapeutic nonadherence?

Output: not following recommended medical or health advice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is therapeutic nonadherence?. ### Response: not following recommended medical or health advice.


Instruction: What is a major contributor to poor control of hypertension and a key barrier to reducing CVD deaths?

Output: health advice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major contributor to poor control of hypertension and a key barrier to reducing CVD deaths?. ### Response: health advice.


Instruction: Adherence rates vary substantially in different populations and are lower for what?

Output: lifestyle change and more behaviorally demanding regimens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adherence rates vary substantially in different populations and are lower for what?. ### Response: lifestyle change and more behaviorally demanding regimens.


Instruction: What type of regimens are more demanding?

Output: behaviorally

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of regimens are more demanding?. ### Response: behaviorally.


Instruction: What are the recommendations for Antihypertensive Medication Adherence Strategies summarized in?

Output: Online Data Supplements 59 and 60.COR LOE RecommendationsI B-R1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for Antihypertensive Medication Adherence Strategies summarized in?. ### Response: Online Data Supplements 59 and 60.COR LOE RecommendationsI B-R1.


Instruction: In adults with hypertension, dosing of what medication once rather than multiple times daily is beneficial?

Output: antihypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adults with hypertension, dosing of what medication once rather than multiple times daily is beneficial?. ### Response: antihypertensive.


Instruction: What is beneficial to improve adherence to antihypertensive therapy?

Output: Use of combination pills

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial to improve adherence to antihypertensive therapy?. ### Response: Use of combination pills.


Instruction: What can be used instead of free individual components?

Output: combination pills

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used instead of free individual components?. ### Response: combination pills.


Instruction: Up to what percentage of patients do not fill their initial prescription?

Output: 25%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Up to what percentage of patients do not fill their initial prescription?. ### Response: 25%.


Instruction: How much of the time does the average patient have possession of antihypertensive medications?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the time does the average patient have possession of antihypertensive medications?. ### Response: 50%.


Instruction: How many patients have sufficiently high adherence to achieve the benefits observed in clinical trials?

Output: 1 in 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients have sufficiently high adherence to achieve the benefits observed in clinical trials?. ### Response: 1 in 5.


Instruction: What are three factors contributing to poor adherence?

Output: myriad, com-plex, and multilevel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are three factors contributing to poor adherence?. ### Response: myriad, com-plex, and multilevel.


Instruction: What contributes to poor adherence?

Output: myriad, com-plex, and multilevel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What contributes to poor adherence?. ### Response: myriad, com-plex, and multilevel.


Instruction: What can be introduced at patient, provider, and healthcare system levels?

Output: solu-tions to improve adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be introduced at patient, provider, and healthcare system levels?. ### Response: solu-tions to improve adherence.


Instruction: Several systematic reviews and meta-analyses have assessed the impact of interventions on adherence to what?

Output: antihyperten-sive medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Several systematic reviews and meta-analyses have assessed the impact of interventions on adherence to what?. ### Response: antihyperten-sive medications.


Instruction: What type of therapy can be modified?

Output: antihypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy can be modified?. ### Response: antihypertensive.


Instruction: No single inter vention is uniquely effective, what is likely to be the most effective approach?

Output: a sustained, coordinated effort that targets all barriers to adherence in an individual

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No single inter vention is uniquely effective, what is likely to be the most effective approach?. ### Response: a sustained, coordinated effort that targets all barriers to adherence in an individual.


Instruction: What are the barriers to medication adherence and the most successful interventions?

Output: Online Data Supplement F

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the barriers to medication adherence and the most successful interventions?. ### Response: Online Data Supplement F.


Instruction: What is the importance of creating an encouraging, blame-free environment in which patients are recognized for achieving treatment goals?

Output: essential

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the importance of creating an encouraging, blame-free environment in which patients are recognized for achieving treatment goals?. ### Response: essential.


Instruction: Who published the 2017 High Blood Pressure Clinical Practice Guideline e39of vascular target organ injury and atherosclerosis?

Output: Whelton et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2017 High Blood Pressure Clinical Practice Guideline e39of vascular target organ injury and atherosclerosis?. ### Response: Whelton et al.


Instruction: High blood pressure readings are associated with an increase in what?

Output: subclinical CVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: High blood pressure readings are associated with an increase in what?. ### Response: subclinical CVD risk.


Instruction: What are carotid intima-media thickness values and coronary artery calcium scores?

Output: cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are carotid intima-media thickness values and coronary artery calcium scores?. ### Response: cardiovascular events.


Instruction: What are carotid intima-media thickness values associated with?

Output: cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are carotid intima-media thickness values associated with?. ### Response: cardiovascular events.


Instruction: What prevents their routine use as surrogate markers in the treatment of hypertension?

Output: inadequate or absent information on the effect of improve-ment in these markers on cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What prevents their routine use as surrogate markers in the treatment of hypertension?. ### Response: inadequate or absent information on the effect of improve-ment in these markers on cardiovascular events.


Instruction: What is a secondary manifestation of hypertension?

Output: LVH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a secondary manifestation of hypertension?. ### Response: LVH.


Instruction: LVH is com-monly measured by what?

Output: electrocardiography, echocardiography, or MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LVH is com-monly measured by what?. ### Response: electrocardiography, echocardiography, or MRI.


Instruction: What is associated with body size?

Output: Left ventricular (LV) mass

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with body size?. ### Response: Left ventricular (LV) mass.


Instruction: What leads to a reduction in LV mass?

Output: S7.2-7–S7.2-9 BP low-ering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What leads to a reduction in LV mass?. ### Response: S7.2-7–S7.2-9 BP low-ering.


Instruction: What was slightly more effective in reducing LVH than a calcium channel blocker?

Output: chlorthalidone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was slightly more effective in reducing LVH than a calcium channel blocker?. ### Response: chlorthalidone.


Instruction: What is enalapril?

Output: ACE inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enalapril?. ### Response: ACE inhibitor.


Instruction: What is alpha-receptor blocker?

Output: doxazo-sin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is alpha-receptor blocker?. ### Response: doxazo-sin.


Instruction: Beta blockers are inferior to what?

Output: angiotensin receptor blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beta blockers are inferior to what?. ### Response: angiotensin receptor blockers.


Instruction: What is also a precursor of AF?

Output: left atrial size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is also a precursor of AF?. ### Response: left atrial size.


Instruction: What are some parameters of diastolic function?

Output: many parameters; a precursor of HF with preserved ejection fraction [HFpEF]);

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some parameters of diastolic function?. ### Response: many parameters; a precursor of HF with preserved ejection fraction [HFpEF]);.


Instruction: How is left atrial size assessed?

Output: both diameter and area

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is left atrial size assessed?. ### Response: both diameter and area.


Instruction: What is not universally recommended during evaluation and management of hypertension in adults?

Output: Assessment of LVH by means of echocardiography or MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not universally recommended during evaluation and management of hypertension in adults?. ### Response: Assessment of LVH by means of echocardiography or MRI.


Instruction: What is limited data on the cost and value of these measures for?

Output: CVD risk reclassification and changes in type or intensity of treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is limited data on the cost and value of these measures for?. ### Response: CVD risk reclassification and changes in type or intensity of treatment.


Instruction: What is most useful in adults who are young ( 18 years of age) or have evidence of sec-ondary hypertension or chronic uncontrolled hypertension?

Output: Assessment of LVH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is most useful in adults who are young ( 18 years of age) or have evidence of sec-ondary hypertension or chronic uncontrolled hypertension?. ### Response: Assessment of LVH.


Instruction: Electrocardiographic criteria for LVH correlate weakly with what?

Output: echocardiographic or MRI definitions of LVH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Electrocardiographic criteria for LVH correlate weakly with what?. ### Response: echocardiographic or MRI definitions of LVH.


Instruction: What are electrocardiographic criteria for LVH less strongly related to?

Output: CVD  outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are electrocardiographic criteria for LVH less strongly related to?. ### Response: CVD  outcomes.


Instruction: Imprecision in lead placement accounts for the poor correlation of electrocardiography measurements with what?

Output: direct imaging results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Imprecision in lead placement accounts for the poor correlation of electrocardiography measurements with what?. ### Response: direct imaging results.


Instruction: Electrocar -diographic LV H has been valuable in what field?

Output: predicting CVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Electrocar -diographic LV H has been valuable in what field?. ### Response: predicting CVD risk.


Instruction: What has been valuable in predicting CVD risk in some reports?

Output: electrocar -diographic LVH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been valuable in predicting CVD risk in some reports?. ### Response: electrocar -diographic LVH.


Instruction: Electrocardiography may also be useful in the assessment of what?

Output: comorbidities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Electrocardiography may also be useful in the assessment of what?. ### Response: comorbidities.


Instruction: What does proteinuria do?

Output: changes inhard outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does proteinuria do?. ### Response: changes inhard outcomes.


Instruction: What is uncertain?

Output: Whether those changes translate to changes inhard outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uncertain?. ### Response: Whether those changes translate to changes inhard outcomes.


Instruction: Why are beta-blockers not used?

Output: imprecision in the studies from a low number ofevents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are beta-blockers not used?. ### Response: imprecision in the studies from a low number ofevents.


Instruction: What was found to have little or no difference compared to placebo or RASi for the CVand kidney outcomes?

Output: beta-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to have little or no difference compared to placebo or RASi for the CVand kidney outcomes?. ### Response: beta-blockers.


Instruction: What did the studies from a low number of events, beta-blockers andCCBs have?

Output: little or no difference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the studies from a low number of events, beta-blockers andCCBs have?. ### Response: little or no difference.


Instruction: What has been extensively studied in appropriately powered trials?

Output: RASi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been extensively studied in appropriately powered trials?. ### Response: RASi.


Instruction: How many relevant direct renin inhibitor studies were there?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many relevant direct renin inhibitor studies were there?. ### Response: 1.


Instruction: What did there be no events in either arm?

Output: direct renin inhibitor study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did there be no events in either arm?. ### Response: direct renin inhibitor study.