Instruction: What is indicated in patients with mitral stenosis and a prior embolic event, even in sinus rhythm (Class I; Level of Evidence B)?

Output: Anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated in patients with mitral stenosis and a prior embolic event, even in sinus rhythm (Class I; Level of Evidence B)?. ### Response: Anticoagulation.


Instruction: What would be most effective in reducing the risk of stroke?

Output: antithrombotic therapy is useful for the primary prevention of stroke in patients with mitral valve prolapse and mitral regurgitation who do not have AF. Comparative-effectiveness trials would be useful to determine which antithrombotic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be most effective in reducing the risk of stroke?. ### Response: antithrombotic therapy is useful for the primary prevention of stroke in patients with mitral valve prolapse and mitral regurgitation who do not have AF. Comparative-effectiveness trials would be useful to determine which antithrombotic.


Instruction: What is indicated in patients with mitral stenosis and left atrial thrombus?

Output: Anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated in patients with mitral stenosis and left atrial thrombus?. ### Response: Anticoagulation.


Instruction: Warfarin (target INR, 2.0–3.0) and low-dose aspi-rin are indicated after aortic valve replacement with bileaflet mechanical prostheses?

Output: 3. Warfarin (target INR, 2.0–3.0) and low-dose aspi-rin are indicated after aortic valve replacement with bileaflet mechanical or current-generation, single-tilting-disk prostheses in patients with no risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Warfarin (target INR, 2.0–3.0) and low-dose aspi-rin are indicated after aortic valve replacement with bileaflet mechanical prostheses?. ### Response: 3. Warfarin (target INR, 2.0–3.0) and low-dose aspi-rin are indicated after aortic valve replacement with bileaflet mechanical or current-generation, single-tilting-disk prostheses in patients with no risk factors.


Instruction: What type of prostheses are indicated in patients with mechanical aortic valve replacement and risk fac-tors?

Output: bioprosthesis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of prostheses are indicated in patients with mechanical aortic valve replacement and risk fac-tors?. ### Response: bioprosthesis.


Instruction: What is the target INR of warfarin?

Output: 2.0 to 3.0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target INR of warfarin?. ### Response: 2.0 to 3.0.


Instruction: How is low-dose aspirin indicated?

Output: after mitral valve replacement with any mechanical valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is low-dose aspirin indicated?. ### Response: after mitral valve replacement with any mechanical valve.


Instruction: What is recommended for the treatment of atrial myxomas?

Output: Surgical excision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for the treatment of atrial myxomas?. ### Response: Surgical excision.


Instruction: What is indicated after mitral valve replacement with any mechanical valve?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated after mitral valve replacement with any mechanical valve?. ### Response: warfarin.


Instruction: What is recommended for symptomatic fibroelastomas?

Output: Surgical intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for symptomatic fibroelastomas?. ### Response: Surgical intervention.


Instruction: What is reasonable after aortic or mitral valve replacement with a bioprosthesis?

Output: Aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable after aortic or mitral valve replacement with a bioprosthesis?. ### Response: Aspirin.


Instruction: What is a class IIa; Level of Evidence B?

Output: Aspirin is reasonable after aortic or mitral valve replacement with a bioprosthesis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIa; Level of Evidence B?. ### Response: Aspirin is reasonable after aortic or mitral valve replacement with a bioprosthesis.


Instruction: What is an INR of 2.0 to 3.0 during the first 3 months after aortic valve replacement with a bioprosthesis?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an INR of 2.0 to 3.0 during the first 3 months after aortic valve replacement with a bioprosthesis?. ### Response: warfarin.


Instruction: What are anticoagulants and antiplatelet agents reasonable for?

Output: patients with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are anticoagulants and antiplatelet agents reasonable for?. ### Response: patients with heart failure.


Instruction: What is reasonable for patients with STEMI and asymptomatic left ventric-ular mural thrombi?

Output: Vitamin K antagonist therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for patients with STEMI and asymptomatic left ventric-ular mural thrombi?. ### Response: Vitamin K antagonist therapy.


Instruction: What is a Class IIa; Level of Evidence C?

Output: Vitamin K antagonist therapy is reasonable for patients with STEMI and asymptomatic left ventric-ular mural thrombi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Class IIa; Level of Evidence C?. ### Response: Vitamin K antagonist therapy is reasonable for patients with STEMI and asymptomatic left ventric-ular mural thrombi.


Instruction: What may be considered for asymptomatic patients with severe mitral stenosis and left atrial dimension 55 mm by echocardiography?

Output: Anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for asymptomatic patients with severe mitral stenosis and left atrial dimension 55 mm by echocardiography?. ### Response: Anticoagulation.


Instruction: What term is used throughout the document to denote BP above the target for a particular population underconsideration?

Output: high BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What term is used throughout the document to denote BP above the target for a particular population underconsideration?. ### Response: high BP.


Instruction: For most adult patients with CKD not receiving dialysis, the target is SBP 120mm Hg (Chapter 3).

Output: high BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For most adult patients with CKD not receiving dialysis, the target is SBP 120mm Hg (Chapter 3).. ### Response: high BP.


Instruction: For adultkidney transplant recipients the target remains what?

Output: SBP <130 mm Hg/DBP <80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For adultkidney transplant recipients the target remains what?. ### Response: SBP <130 mm Hg/DBP <80 mm Hg.


Instruction: What is the target for adultkidney transplant recipients?

Output: SBP <130 mm Hg/DBP <80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target for adultkidney transplant recipients?. ### Response: SBP <130 mm Hg/DBP <80 mm Hg.


Instruction: What are the targets for pediatric populations age-dependent?

Output: MAP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the targets for pediatric populations age-dependent?. ### Response: MAP.


Instruction: What term have we avoided when referring to treatment decisions?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What term have we avoided when referring to treatment decisions?. ### Response: hypertension.


Instruction: What does the term "hypertension" require a single numerical de finition and does not necessarily facilitate?

Output: BP management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the term "hypertension" require a single numerical de finition and does not necessarily facilitate?. ### Response: BP management.


Instruction: What is preferred to fice BPmeasurement for the management of high BP in adults?

Output: standardized of ﬁce BP measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preferred to fice BPmeasurement for the management of high BP in adults?. ### Response: standardized of ﬁce BP measurement.


Instruction: An oscillometric BP device may be preferable to what?

Output: a manual BP device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: An oscillometric BP device may be preferable to what?. ### Response: a manual BP device.


Instruction: What emphasizes adequate preparations for BP measurement, not the type of equipment?

Output: standardization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What emphasizes adequate preparations for BP measurement, not the type of equipment?. ### Response: standardization.


Instruction: What is the preferred method of stan-dardized of fice BP measurement?

Output: Automated of ﬁce BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preferred method of stan-dardized of fice BP measurement?. ### Response: Automated of ﬁce BP.


Instruction: What can be used to measure BP among patients with atrial fibrillation?

Output: Oscillometric devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to measure BP among patients with atrial fibrillation?. ### Response: Oscillometric devices.


Instruction: What should out-of-fence BP measurements be used to complement?

Output: standardized of ﬁce BP readingsfor the management of high BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should out-of-fence BP measurements be used to complement?. ### Response: standardized of ﬁce BP readingsfor the management of high BP.


Instruction: What is HBPM?

Output: home BP monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HBPM?. ### Response: home BP monitoring.


Instruction: How much sodium do we recommend per day in patients with high BP and CKD?

Output: <2 g

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much sodium do we recommend per day in patients with high BP and CKD?. ### Response: <2 g.


Instruction: What is the recommended amount of sodium per day?

Output: <2 g

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended amount of sodium per day?. ### Response: <2 g.


Instruction: How many g of sodium chloride per day are recommended for high blood pressure?

Output: <5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many g of sodium chloride per day are recommended for high blood pressure?. ### Response: <5.


Instruction: What type of diet is not appropriate for patients with sodium-wasting nephropathy?

Output: Dietary sodium restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet is not appropriate for patients with sodium-wasting nephropathy?. ### Response: Dietary sodium restriction.


Instruction: What is DASH?

Output: Dietary Approaches to Stop Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DASH?. ### Response: Dietary Approaches to Stop Hypertension.


Instruction: What may not be appropriate for patients with advanced CKD or hyporeninemichypoaldosteronism?

Output: dialysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not be appropriate for patients with advanced CKD or hyporeninemichypoaldosteronism?. ### Response: dialysis.


Instruction: What is the cumulative duration of moderate-intensity physical activity?

Output: 150 minutes per week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cumulative duration of moderate-intensity physical activity?. ### Response: 150 minutes per week.


Instruction: How many minutes per week does a person need to do moderate intensity physical activity for?

Output: 150

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many minutes per week does a person need to do moderate intensity physical activity for?. ### Response: 150.


Instruction: What are some factors to consider when deciding on the intensity of physical activity in a week?

Output: cardiorespiratory ﬁtness status, physical limitations, cognitive function, and risk of fall

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some factors to consider when deciding on the intensity of physical activity in a week?. ### Response: cardiorespiratory ﬁtness status, physical limitations, cognitive function, and risk of fall.


Instruction: What type of falls are considered when deciding on the implementation and intensity of physical activity interventions in individual?

Output: risk of fall

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of falls are considered when deciding on the implementation and intensity of physical activity interventions in individual?. ### Response: risk of fall.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 34 of 134 What would have been included in the SR by Saiz et al. (2018)?

Output: SPRINT participants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 34 of 134 What would have been included in the SR by Saiz et al. (2018)?. ### Response: SPRINT participants.


Instruction: What could explain why Saiz et al. (2018) did not find benefits for reducing SBP below 150 mm Hg?

Output: Only a small proportion of SPRINT participants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could explain why Saiz et al. (2018) did not find benefits for reducing SBP below 150 mm Hg?. ### Response: Only a small proportion of SPRINT participants.


Instruction: What does the SR and meta-analysis suggest?

Output: a reduction in stroke recurrence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the SR and meta-analysis suggest?. ### Response: a reduction in stroke recurrence.


Instruction: What does Brunstrom et al. 2017 suggest?

Output: benefit of treatment in patients with diabetes may be limited to those with a baseline SBP of >140 mm Hg or to an achieved SBP of 130 -140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Brunstrom et al. 2017 suggest?. ### Response: benefit of treatment in patients with diabetes may be limited to those with a baseline SBP of >140 mm Hg or to an achieved SBP of 130 -140 mm Hg.


Instruction: What is the baseline SBP of a diabetic?

Output: >140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the baseline SBP of a diabetic?. ### Response: >140 mm Hg.


Instruction: How is the benefit of treatment limited?

Output: those with a baseline SBP of >140 mm Hg or to an achieved SBP of 130 -140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the benefit of treatment limited?. ### Response: those with a baseline SBP of >140 mm Hg or to an achieved SBP of 130 -140 mm Hg.


Instruction: What type of diabetes was the primary focus of the available evidence?

Output: type 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes was the primary focus of the available evidence?. ### Response: type 2.


Instruction: What kind of evidence was limited for type 1 diabetes?

Output: available

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What kind of evidence was limited for type 1 diabetes?. ### Response: available.


Instruction: The SR by Ettehad et al. (2016) showed the reduction in the rates of cardiovascular outcomes from a 10 mm Hg reduction in blood?

Output: did not differ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The SR by Ettehad et al. (2016) showed the reduction in the rates of cardiovascular outcomes from a 10 mm Hg reduction in blood?. ### Response: did not differ.


Instruction: What was the result of a 10 mm Hg reduction in blood pressure?

Output: proportional reduction in the rates of cardiovascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of a 10 mm Hg reduction in blood pressure?. ### Response: proportional reduction in the rates of cardiovascular outcomes.


Instruction: What did not differ among people with prior cardiovascular disease events, coronary heart disease, CHF, or cerebrovascular disease?

Output: the proportional reduction in the rates of cardiovascular outcomes resulting from a 10 mm Hg reduction in blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not differ among people with prior cardiovascular disease events, coronary heart disease, CHF, or cerebrovascular disease?. ### Response: the proportional reduction in the rates of cardiovascular outcomes resulting from a 10 mm Hg reduction in blood pressure.


Instruction: How many other SRs examined the risk of stroke recurrence among patients receiving more intensive HTN therapy?

Output: Two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many other SRs examined the risk of stroke recurrence among patients receiving more intensive HTN therapy?. ### Response: Two.


Instruction: What did these SRs suggest a reduction in?

Output: stroke recurrence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did these SRs suggest a reduction in?. ### Response: stroke recurrence.


Instruction: For many patients, benefits of intensive therapy seem to outweigh harms?

Output: some people might prefer not to take

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For many patients, benefits of intensive therapy seem to outweigh harms?. ### Response: some people might prefer not to take.


Instruction: What does an SBP goal of 130 not mean?

Output: it must always be achieved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does an SBP goal of 130 not mean?. ### Response: it must always be achieved.


Instruction: What does the SBP goal of 130 mean?

Output: mm Hg or less

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the SBP goal of 130 mean?. ### Response: mm Hg or less.


Instruction: What may older or frail people do if they develop side effects while titrating therapy to achieve this lower threshold?

Output: they may wish to have medications tapered back or changed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may older or frail people do if they develop side effects while titrating therapy to achieve this lower threshold?. ### Response: they may wish to have medications tapered back or changed.


Instruction: What did some patients not want to take for treatment of HTN?

Output: medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some patients not want to take for treatment of HTN?. ### Response: medications.


Instruction: What may limit the ability to achieve lower targets of SBP with intensive treatment?

Output: medications for treatment of HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may limit the ability to achieve lower targets of SBP with intensive treatment?. ### Response: medications for treatment of HTN.


Instruction: What may require frequent visits?

Output: intensive treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may require frequent visits?. ### Response: intensive treatment.


Instruction: What does Ettehad et al. (2016) demonstrate benefit in lowering SBP?

Output: the results from the SR by Ettehad et al. (2016) do demonstrate benefit in lowering SBP for those between 130 and 150 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Ettehad et al. (2016) demonstrate benefit in lowering SBP?. ### Response: the results from the SR by Ettehad et al. (2016) do demonstrate benefit in lowering SBP for those between 130 and 150 mm Hg.


Instruction: What does lowering SBP by 10 mm Hg reduce the risk of?

Output: cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lowering SBP by 10 mm Hg reduce the risk of?. ### Response: cardiovascular events.


Instruction: What is there strong evidence from one SR suggesting?

Output: lowering SBP by 10 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there strong evidence from one SR suggesting?. ### Response: lowering SBP by 10 mm Hg.


Instruction: Why is there inconsistencies among other studies?

Output: comparing a standard threshold with more intensive therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there inconsistencies among other studies?. ### Response: comparing a standard threshold with more intensive therapy.


Instruction: How many adults under the age of 60 were included in the GRADE methodology?

Output: very few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many adults under the age of 60 were included in the GRADE methodology?. ### Response: very few.


Instruction: What does more intensive therapy often require?

Output: additional medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does more intensive therapy often require?. ### Response: additional medications.


Instruction: What do some people prefer not to take?

Output: medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do some people prefer not to take?. ### Response: medications.


Instruction: What are the results in contrast to for the older population of age 60 who have hypertension?

Output: stronger evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results in contrast to for the older population of age 60 who have hypertension?. ### Response: stronger evidence.


Instruction: What percentage of patients had effective hemostasis?

Output: 79%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients had effective hemostasis?. ### Response: 79%.


Instruction: What is the name of the drug that is in late-stage review byregulatory?

Output: Andexanet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is in late-stage review byregulatory?. ### Response: Andexanet.


Instruction: What percentage of patients have hemostasis?

Output: 79%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have hemostasis?. ### Response: 79%.


Instruction: What is Ciraparantag a reversalagent for?

Output: unfractionated heparin (UFH), LMWHs,fondaparinux, and the oral direct Xa and IIa inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Ciraparantag a reversalagent for?. ### Response: unfractionated heparin (UFH), LMWHs,fondaparinux, and the oral direct Xa and IIa inhibitors.


Instruction: How does it bind to targets?

Output: through noncovalent hydrogen bonding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does it bind to targets?. ### Response: through noncovalent hydrogen bonding.


Instruction: What does NOAC do?

Output: Consider absorption-activated charcoal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NOAC do?. ### Response: Consider absorption-activated charcoal.


Instruction: What does VKA do if reversalagent is not available?

Output: Delay until INR ≤2.0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does VKA do if reversalagent is not available?. ### Response: Delay until INR ≤2.0.


Instruction: PRBCs, FFP, platelets, as plasmaexpander, what does FFP do?

Output: platelets as necessary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PRBCs, FFP, platelets, as plasmaexpander, what does FFP do?. ### Response: platelets as necessary.


Instruction: What is used to establish hemostasis?

Output: Mechanicalcompression/intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to establish hemostasis?. ### Response: Mechanicalcompression/intervention.


Instruction: PRBCs, FFP, platelets as necessaryWhat is considered if last dose 2-4 h?

Output: absorption-activated charcoal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PRBCs, FFP, platelets as necessaryWhat is considered if last dose 2-4 h?. ### Response: absorption-activated charcoal.


Instruction: What is considered absorption activated charcoal?

Output: NOAC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered absorption activated charcoal?. ### Response: NOAC.


Instruction: What is frozen plasma?

Output: FFP ¼fresh

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is frozen plasma?. ### Response: FFP ¼fresh.


Instruction: What is PRBC 14packed RBCs?

Output: ¼

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PRBC 14packed RBCs?. ### Response: ¼.


Instruction: What is the class of LV dysfunction?

Output: Class IIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of LV dysfunction?. ### Response: Class IIa.


Instruction: What can be added to the basic regimen of  -blocker, ACE inhibitor, and thiazide?

Output: a long-acting dihydropyridine CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be added to the basic regimen of  -blocker, ACE inhibitor, and thiazide?. ### Response: a long-acting dihydropyridine CCB.


Instruction: What should be used with cau-tion in patients with symptomatic CAD and hypertension?

Output: The combination of a β -blocker and either of the nondihydropyridine CCBs (diltiazem or verapamil)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used with cau-tion in patients with symptomatic CAD and hypertension?. ### Response: The combination of a β -blocker and either of the nondihydropyridine CCBs (diltiazem or verapamil).


Instruction: What is the increased risk of significant brady-arrhythmias and HF?

Output: symptomatic CAD and hyperten-sion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the increased risk of significant brady-arrhythmias and HF?. ### Response: symptomatic CAD and hyperten-sion.


Instruction: For patients with stable angina, the BP target is what?

Output: <140/90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients with stable angina, the BP target is what?. ### Response: <140/90 mm Hg.


Instruction: What is the BP target for patients with stable angina?

Output: <140/90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BP target for patients with stable angina?. ### Response: <140/90 mm Hg.


Instruction: What is a lower target BP in some individuals with CAD?

Output: (<130/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a lower target BP in some individuals with CAD?. ### Response: (<130/80 mm Hg.


Instruction: What are some individuals with CAD risk equivalents?

Output: carotid artery disease, PAD, abdomi-nal aort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some individuals with CAD risk equivalents?. ### Response: carotid artery disease, PAD, abdomi-nal aort.


Instruction: What is a class IIb; Level of Evidence B?

Output: CAD risk equivalents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIb; Level of Evidence B?. ### Response: CAD risk equivalents.


Instruction: There are no special contraindications for the use of what drugs?

Output: antiplatelet or anticoagu-lant drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are no special contraindications for the use of what drugs?. ### Response: antiplatelet or anticoagu-lant drugs.


Instruction: What should be lowered with-out delay in patients with uncontrolled severe hypertension who are taking antiplatelet or anticoagulant drugs?

Output: the BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be lowered with-out delay in patients with uncontrolled severe hypertension who are taking antiplatelet or anticoagulant drugs?. ### Response: the BP.


Instruction: What should reduce the risk of hemorrhagic stroke?

Output: the BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should reduce the risk of hemorrhagic stroke?. ### Response: the BP.


Instruction: What is a major risk factor for CVD?

Output: brady-arrhythmias and HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major risk factor for CVD?. ### Response: brady-arrhythmias and HF.


Instruction: What is the impact of hyper -tension on ACS outcomes not well described?

Output: major risk factor for CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of hyper -tension on ACS outcomes not well described?. ### Response: major risk factor for CVD.


Instruction: How many data are available on specific treatments for hypertension in patients with STEMI or non-ST-segment-elevation ACS?

Output: Few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many data are available on specific treatments for hypertension in patients with STEMI or non-ST-segment-elevation ACS?. ### Response: Few.


Instruction: What is a non-ST-segment-elevation ACS?

Output: STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a non-ST-segment-elevation ACS?. ### Response: STEMI.


Instruction: What is the ACTION Registry-Get With The Guidelines?

Output: Acute Coronary Treatment and Intervention Outcomes Network

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACTION Registry-Get With The Guidelines?. ### Response: Acute Coronary Treatment and Intervention Outcomes Network.


Instruction: What is the prevalence of hypertension among ACS patients?

Output: double

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of hypertension among ACS patients?. ### Response: double.


Instruction: What percentage of patients with STEMI have hypertension?

Output: 65.2%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with STEMI have hypertension?. ### Response: 65.2%.


Instruction: How much do hypertension prevalence rates double among individuals >75 versus those 45?

Output: double

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much do hypertension prevalence rates double among individuals >75 versus those 45?. ### Response: double.


Instruction: What is the impact of hypertension on outcomes in ACS?

Output: com-plex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of hypertension on outcomes in ACS?. ### Response: com-plex.


Instruction: In patients with stabilized ACS, what was an independent predictor of death and MI at 90 days?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with stabilized ACS, what was an independent predictor of death and MI at 90 days?. ### Response: hypertension.


Instruction: What is a predictor of death and MI at 90 days?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of death and MI at 90 days?. ### Response: hypertension.


Instruction: Hypertension is integrated into the Thrombolysis in Myocardial Infarction risk score for UA/NSTEMI as one of several classic risk factors for CAD?

Output: 179

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertension is integrated into the Thrombolysis in Myocardial Infarction risk score for UA/NSTEMI as one of several classic risk factors for CAD?. ### Response: 179.


Instruction: What was independently associated with the composite end point of mortality and recurrent ischemic events?

Output: the variable of ≥ 3 risk factors for CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was independently associated with the composite end point of mortality and recurrent ischemic events?. ### Response: the variable of ≥ 3 risk factors for CAD.


Instruction: What is the gender influence on thediagnostic accuracy of 64-slice multisplice computed tomographycoronary angiography for detection of obstructive coronary arterydisease?

Output: Sex differences in mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the gender influence on thediagnostic accuracy of 64-slice multisplice computed tomographycoronary angiography for detection of obstructive coronary arterydisease?. ### Response: Sex differences in mortality.


Instruction: What is Motoyama S, Sarai M, Harigaya H, et al?

Output: Kondo T

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Motoyama S, Sarai M, Harigaya H, et al?. ### Response: Kondo T.


Instruction: What are the characteristics of atherosclerotic plaques that result in acute coronary syndrome?

Output: Computed tomographicangiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the characteristics of atherosclerotic plaques that result in acute coronary syndrome?. ### Response: Computed tomographicangiography.


Instruction: What is the J Am Coll Cardiol. 2009;54:49–57.212?

Output: Computed tomographicangiography characteristics of atherosclerotic plaques subsequentlyresulting in acute coronary syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2009;54:49–57.212?. ### Response: Computed tomographicangiography characteristics of atherosclerotic plaques subsequentlyresulting in acute coronary syndrome.


Instruction: Who is the author of the exploratoryanalysis?

Output: Shaw LJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the exploratoryanalysis?. ### Response: Shaw LJ.


Instruction: What is exploratoryanalysis?

Output: Sex differences in mortality asso-ciated with computed tomographic angiographic measuremen ts ofobstructive and nonobstructive coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is exploratoryanalysis?. ### Response: Sex differences in mortality asso-ciated with computed tomographic angiographic measuremen ts ofobstructive and nonobstructive coronary artery disease.


Instruction: What is the name of the study that investigated multislice computed tomo-graphic characteristics of coronary lesions in acute coronary syn-dromes?

Output: CONFIRM (Coronary CT Angiography Evaluation forClinical Outcomes: An International Multicenter) Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated multislice computed tomo-graphic characteristics of coronary lesions in acute coronary syn-dromes?. ### Response: CONFIRM (Coronary CT Angiography Evaluation forClinical Outcomes: An International Multicenter) Registry.


Instruction: What does CONFIRM stand for?

Output: Coronary CT Angiography Evaluation forClinical Outcomes: An International Multicenter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CONFIRM stand for?. ### Response: Coronary CT Angiography Evaluation forClinical Outcomes: An International Multicenter.


Instruction: What is the name of the registry that evaluates coronary CT angiography for clinical outcomes?

Output: CONFIRM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry that evaluates coronary CT angiography for clinical outcomes?. ### Response: CONFIRM.


Instruction: What is a marker of inducible regionalmyocardial hypoperfusion from severe coronary artery stenoses?

Output: coronary CT angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a marker of inducible regionalmyocardial hypoperfusion from severe coronary artery stenoses?. ### Response: coronary CT angiography.


Instruction: What is the name of the prospective2-center study of 2,583 patients undergoing 64-detector row coronary computed tomography?

Output: Mortality risk in symptomaticpatients with nonobstructive coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective2-center study of 2,583 patients undergoing 64-detector row coronary computed tomography?. ### Response: Mortality risk in symptomaticpatients with nonobstructive coronary artery disease.


Instruction: How many patients underwent 64-detector row coronarycomputed tomographic angiography?

Output: 2,583

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent 64-detector row coronarycomputed tomographic angiography?. ### Response: 2,583.


Instruction: What did the prospective2-center study of 2,583 patients involve?

Output: 64-detector row coronarycomputed tomographic angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the prospective2-center study of 2,583 patients involve?. ### Response: 64-detector row coronarycomputed tomographic angiography.


Instruction: When was the J Am Coll Cardiol 58:510–9.217 published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 58:510–9.217 published?. ### Response: 2011.


Instruction: What does the American College of Cardiology/American Heart Association expert consensus document?

Output: electron-beam computed tomography for the diagnosis andprognosis of coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American College of Cardiology/American Heart Association expert consensus document?. ### Response: electron-beam computed tomography for the diagnosis andprognosis of coronary artery disease.


Instruction: What does electron-beam computed tomography do for the diagnosis andprognosis of coronary artery disease?

Output: detection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does electron-beam computed tomography do for the diagnosis andprognosis of coronary artery disease?. ### Response: detection.


Instruction: When did J Am Coll Cardiol. 2000;32:326–40.219?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2000;32:326–40.219?. ### Response: 2000.


Instruction: What is the symptomaticstatus on the prevalence of obstructive coronary artery disease inpatients with zero calcium score?

Output: Influence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the symptomaticstatus on the prevalence of obstructive coronary artery disease inpatients with zero calcium score?. ### Response: Influence.


Instruction: Atherosclerosis. 2009;203:533–7.220.

Output: omaticstatus on the prevalence of obstructive coronary artery disease inpatients with zero calcium score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atherosclerosis. 2009;203:533–7.220.. ### Response: omaticstatus on the prevalence of obstructive coronary artery disease inpatients with zero calcium score.


Instruction: Cademartiri F, Maffei E, Palumbo A, et al. Diagnostic accuracy of computed tomography in patients with a zerocalcium score.

Output: 2010;20:81–7.221

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cademartiri F, Maffei E, Palumbo A, et al. Diagnostic accuracy of computed tomography in patients with a zerocalcium score.. ### Response: 2010;20:81–7.221.


Instruction: What is an effective filter before catheter angiography?

Output: Multislice spiral computed tomo-graphic angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an effective filter before catheter angiography?. ### Response: Multislice spiral computed tomo-graphic angiography.


Instruction: What is a noninvasive eval-uation with multislice computed tomography in suspected ac ute?

Output: Sex differences in mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a noninvasive eval-uation with multislice computed tomography in suspected ac ute?. ### Response: Sex differences in mortality.


Instruction: What would plant patients accept the tradeoffs of side effects of aCCB or an ARB in exchange for the possible bene fit of pro-longed graft survival?

Output: high BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would plant patients accept the tradeoffs of side effects of aCCB or an ARB in exchange for the possible bene fit of pro-longed graft survival?. ### Response: high BP.


Instruction: What is the recommendation assuming that an antihypertensive agent will be started for thetreatment of high BP?

Output: the guideline is to facilitate thedecision on the choice of the agent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommendation assuming that an antihypertensive agent will be started for thetreatment of high BP?. ### Response: the guideline is to facilitate thedecision on the choice of the agent.


Instruction: What are generic CCBs and generic ARBs inexpensive in most countries?

Output: these drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are generic CCBs and generic ARBs inexpensive in most countries?. ### Response: these drugs.


Instruction: What is the guideline to facilitating the decision on the choice of the agent?

Output: local availability and cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the guideline to facilitating the decision on the choice of the agent?. ### Response: local availability and cost.


Instruction: In what setting are generic drugs most likely to beavailable at even lower cost?

Output: resource-limited

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what setting are generic drugs most likely to beavailable at even lower cost?. ### Response: resource-limited.


Instruction: What is the cost of graft failure?

Output: high ﬁnancial andhuman cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost of graft failure?. ### Response: high ﬁnancial andhuman cost.


Instruction: What is a cost-effective way to initiate a CCB orARB?

Output: lowcosts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cost-effective way to initiate a CCB orARB?. ### Response: lowcosts.


Instruction: How has a formaleconomic analysis been performed in the transplantation setting?

Output: not beenperformed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How has a formaleconomic analysis been performed in the transplantation setting?. ### Response: not beenperformed.


Instruction: What can be dif ficultto control in kidney transplant recipients?

Output: High BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be dif ficultto control in kidney transplant recipients?. ### Response: High BP.


Instruction: How many antihypertensive agents do most patients need?

Output: more than 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many antihypertensive agents do most patients need?. ### Response: more than 1.


Instruction: What should be selected with the understanding that other medi-cations may be required to achieve BP control?

Output: antihy-pertensive agent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be selected with the understanding that other medi-cations may be required to achieve BP control?. ### Response: antihy-pertensive agent.


Instruction: What may be required to achieve BP control?

Output: other medi-cations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be required to achieve BP control?. ### Response: other medi-cations.


Instruction: What should patients with evidence of volume overload and high BP be treated with before considering an ARB or CCB?

Output: diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with evidence of volume overload and high BP be treated with before considering an ARB or CCB?. ### Response: diuretics.


Instruction: Women trying to conceive or who are pregnant should betreated with what?

Output: a CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Women trying to conceive or who are pregnant should betreated with what?. ### Response: a CCB.


Instruction: What is generally safe during preg-nancy and lactation?

Output: CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is generally safe during preg-nancy and lactation?. ### Response: CCB.


Instruction: What is contraindicated in these conditions?

Output: ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is contraindicated in these conditions?. ### Response: ARB.


Instruction: In kidney transplant recipients with pro-teinuria and highBP, what should be considered first?

Output: ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In kidney transplant recipients with pro-teinuria and highBP, what should be considered first?. ### Response: ARB.


Instruction: What can be confused with other causes of graft dysfunction?

Output: acute negative effect of an ARB on GFR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be confused with other causes of graft dysfunction?. ### Response: acute negative effect of an ARB on GFR.


Instruction: What should be considered as the first-line antihypertensive agent for most transplantpatients?

Output: ARB or CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered as the first-line antihypertensive agent for most transplantpatients?. ### Response: ARB or CCB.


Instruction: What would most patient subgroups value as a high-priority outcome?

Output: graftsurvival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would most patient subgroups value as a high-priority outcome?. ### Response: graftsurvival.


Instruction: What should the choice of class(i.e., ARB vs. CCB) and specific agent be based on?

Output: local availability and cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the choice of class(i.e., ARB vs. CCB) and specific agent be based on?. ### Response: local availability and cost.


Instruction: What are some advantages of using an ARB or CCB for high BP in kidney transplantrecipients?

Output: physician familiarity with theseagents, well-known side-effect pro ﬁles, availability, and lowcosts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some advantages of using an ARB or CCB for high BP in kidney transplantrecipients?. ### Response: physician familiarity with theseagents, well-known side-effect pro ﬁles, availability, and lowcosts.


Instruction: What are well-known side-effect pro files?

Output: aCCB or an ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are well-known side-effect pro files?. ### Response: aCCB or an ARB.


Instruction: What is a strong reason for the potential prevention of transplantwww.kidney-international.org?

Output: acute negative effect of an ARB on GFRcan be confused with other causes of graft dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strong reason for the potential prevention of transplantwww.kidney-international.org?. ### Response: acute negative effect of an ARB on GFRcan be confused with other causes of graft dysfunction.


Instruction: What can be useful for follow-up assessment at 2-year or longer inter-vals in patients with SIHD with prior evidence ofsilent ischemia or who are at high risk for a recur-rent cardiac event?

Output: Nuclear MPI, echocardiography, or CMR with ei-ther exercise or pharmacological stress

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be useful for follow-up assessment at 2-year or longer inter-vals in patients with SIHD with prior evidence ofsilent ischemia or who are at high risk for a recur-rent cardiac event?. ### Response: Nuclear MPI, echocardiography, or CMR with ei-ther exercise or pharmacological stress.


Instruction: Nuclear MPI, echocardiography, or CMR with ei-ther exercise or pharmacological stress can be used in what type of patient?

Output: patients with SIHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nuclear MPI, echocardiography, or CMR with ei-ther exercise or pharmacological stress can be used in what type of patient?. ### Response: patients with SIHD.


Instruction: What is the level of evidence for incomplete coronaryrevascularization?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for incomplete coronaryrevascularization?. ### Response: C.


Instruction: What might be considered for follow-upassessment in patients with SIHD who have an uninterpretableECG?

Output: evaluation ofincomplete revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered for follow-upassessment in patients with SIHD who have an uninterpretableECG?. ### Response: evaluation ofincomplete revascularization.


Instruction: What type of ischemia are patients with SIHD at high risk for a recurrent cardiac event at risk for?

Output: silent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of ischemia are patients with SIHD at high risk for a recurrent cardiac event at risk for?. ### Response: silent.


Instruction: What is the level of evidence for SIHD?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for SIHD?. ### Response: C.


Instruction: What type of ECG testing is not well established in patients with no new or worsening symptoms?

Output: annual surveillance exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of ECG testing is not well established in patients with no new or worsening symptoms?. ### Response: annual surveillance exercise.


Instruction: Nuclear MPI, echocardiography, and electrocardiography are examples of what?

Output: Class IIa1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nuclear MPI, echocardiography, and electrocardiography are examples of what?. ### Response: Class IIa1.


Instruction: What is not recommended for follow-up assessment in patients with SIHD if performed more frequently than a) 5-year intervals after CABG or b) 2-yearintervals after PCI?

Output: Nuclear MPI, echocardiography, or CMR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for follow-up assessment in patients with SIHD if performed more frequently than a) 5-year intervals after CABG or b) 2-yearintervals after PCI?. ### Response: Nuclear MPI, echocardiography, or CMR.


Instruction: What is the Level of Evidence: C )Class III: No Benefit1?

Output: annual surveillance exercise ECG testing isnot well established

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence: C )Class III: No Benefit1?. ### Response: annual surveillance exercise ECG testing isnot well established.


Instruction: How long after PCI is there a 2-year interval?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after PCI is there a 2-year interval?. ### Response: 5-year.


Instruction: What is the level of evidence for noninvasive testing in known SIHD?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for noninvasive testing in known SIHD?. ### Response: C.


Instruction: How does the appropriateness of performing noninvasive testing inpatients depend on?

Output: factorsrelated to the likelihood of significant findings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the appropriateness of performing noninvasive testing inpatients depend on?. ### Response: factorsrelated to the likelihood of significant findings.


Instruction: What is asymptomatic or have stable symp-toms?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic or have stable symp-toms?. ### Response: patients.


Instruction: What depends on factors related to the likelihood of significant findings?

Output: The appropriateness of performing noninvasive testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What depends on factors related to the likelihood of significant findings?. ### Response: The appropriateness of performing noninvasive testing.


Instruction: The data supporting follow-up testing are sparse and insufficient to support what?

Output: routine, repeat testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The data supporting follow-up testing are sparse and insufficient to support what?. ### Response: routine, repeat testing.


Instruction: What is insufficient to support routine, repeat testing in asymptomatic individuals?

Output: The data supporting follow-up testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is insufficient to support routine, repeat testing in asymptomatic individuals?. ### Response: The data supporting follow-up testing.


Instruction: Evidence exists that persistent ische-mia on testing is a prognostically poor finding?

Output: encing the Use of Follow-Up Testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence exists that persistent ische-mia on testing is a prognostically poor finding?. ### Response: encing the Use of Follow-Up Testing.


Instruction: How many patients with SIHD were enrolled in the COURAGE trial nuclear substudy?

Output: 314

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with SIHD were enrolled in the COURAGE trial nuclear substudy?. ### Response: 314.


Instruction: What isduction in the ischemic myocardium associated with?

Output: reduction in the incidence of death or MIcombined

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isduction in the ischemic myocardium associated with?. ### Response: reduction in the incidence of death or MIcombined.


Instruction: What is unadjusted reduction in the incidence of death or MI combined?

Output: 306

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unadjusted reduction in the incidence of death or MI combined?. ### Response: 306.


Instruction: In the BARI 2D trial, at 1 year of follow-up, what were associated with higher rates ofdeath or MI?

Output: more extensive and severe stress myocardial perfusionSPECT abnormalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the BARI 2D trial, at 1 year of follow-up, what were associated with higher rates ofdeath or MI?. ### Response: more extensive and severe stress myocardial perfusionSPECT abnormalities.


Instruction: What are some circumstances in which a decision to perform follow-up testing is thought to bewarranted in the absence of a change in clinical status?

Output: evaluation ofincomplete revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some circumstances in which a decision to perform follow-up testing is thought to bewarranted in the absence of a change in clinical status?. ### Response: evaluation ofincomplete revascularization.


Instruction: Evaluation of incomplete revascularization, assessment of the adequacy of what?

Output: follow-up testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evaluation of incomplete revascularization, assessment of the adequacy of what?. ### Response: follow-up testing.


Instruction: Who is the e13ACC/AHA TASK FORCE MEMBERS Glenn N. Levine, MD, FACC, FAHA, Chair?

Output: Patrick T. O’Gara, MD, MACC, FAHA, Chair-Elect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the e13ACC/AHA TASK FORCE MEMBERS Glenn N. Levine, MD, FACC, FAHA, Chair?. ### Response: Patrick T. O’Gara, MD, MACC, FAHA, Chair-Elect.


Instruction: What is Patrick T. O’Gara’s position?

Output: Chair-Elect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Patrick T. O’Gara’s position?. ### Response: Chair-Elect.


Instruction: Who is Sana M. Al-Khatib?

Output: MD, MHS, FACC, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Sana M. Al-Khatib?. ### Response: MD, MHS, FACC, FAHA.


Instruction: What is Kim K. Birtcher's specialty?

Output: PharmD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Kim K. Birtcher's specialty?. ### Response: PharmD.


Instruction: What is Biykem Bozkurt's profession?

Output: MD, PhD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Biykem Bozkurt's profession?. ### Response: MD, PhD.


Instruction: Who is the MD, MPH, MACC***?

Output: Ralph G. Brindis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the MD, MPH, MACC***?. ### Response: Ralph G. Brindis.


Instruction: Who is the MD, FACC, FAHA?

Output: José A. Joglar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the MD, FACC, FAHA?. ### Response: José A. Joglar.


Instruction: What is the name of the doctor who is a FAHA***?

Output: Susan J. Pressler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the doctor who is a FAHA***?. ### Response: Susan J. Pressler.


Instruction: Who is Susan J. Pressler?

Output: PhD, RN, FAHA***

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Susan J. Pressler?. ### Response: PhD, RN, FAHA***.


Instruction: Who is Barbara Riegel?

Output: PhD, RN, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Barbara Riegel?. ### Response: PhD, RN, FAHA.


Instruction: What is Duminda N. Wijeysundera's profession?

Output: American Society for Preventive Cardiology Representative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Duminda N. Wijeysundera's profession?. ### Response: American Society for Preventive Cardiology Representative.


Instruction: What is the name of the American Pharmacists Association Representative?

Output: Glenn N. Levine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the American Pharmacists Association Representative?. ### Response: Glenn N. Levine.


Instruction: Who is the ACC/AHA Prevention Subcommittee Liaison?

Output: American Academy of Physician Assistants Representative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the ACC/AHA Prevention Subcommittee Liaison?. ### Response: American Academy of Physician Assistants Representative.


Instruction: Which organization is the Task Force Liaison with?

Output: American Academy of Physician Assistants Representative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which organization is the Task Force Liaison with?. ### Response: American Academy of Physician Assistants Representative.


Instruction: What was the name of the former Task Force member?

Output: Jonathan L. Halperin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the former Task Force member?. ### Response: Jonathan L. Halperin.


Instruction: When was this document approved?

Output: September 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this document approved?. ### Response: September 2017.


Instruction: Who approved this document?

Output: American College of Cardiology Clinical Policy Approval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who approved this document?. ### Response: American College of Cardiology Clinical Policy Approval.


Instruction: What committee approved the document in September 2017?

Output: American College of Cardiology Clinical Policy Approval Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What committee approved the document in September 2017?. ### Response: American College of Cardiology Clinical Policy Approval Committee.


Instruction: When did the American Heart Association Executive Committee meet?

Output: October 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the American Heart Association Executive Committee meet?. ### Response: October 2017.


Instruction: Where is the Comprehensive RWI Data Supplement table available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Comprehensive RWI Data Supplement table available?. ### Response: http://hyper.ahajournals.org.


Instruction: What is the online Data Supplement available at?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the online Data Supplement available at?. ### Response: http://hyper.ahajournals.org.


Instruction: What is the name of the person who was a part of the 2017 National Football League?

Output: Glenn N. Levine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who was a part of the 2017 National Football League?. ### Response: Glenn N. Levine.


Instruction: What is another name for a person who is a member of the national football league?

Output: e13ACC/AHA TASK FORCE MEMBERS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for a person who is a member of the national football league?. ### Response: e13ACC/AHA TASK FORCE MEMBERS.


Instruction: What is the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Instruction: What is the name of the re-port of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the re-port of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery.


Instruction: What are the 1999 Guidelines for Coronary Artery Bypass Graft Surgery?

Output: Committee to Update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 1999 Guidelines for Coronary Artery Bypass Graft Surgery?. ### Response: Committee to Update.


Instruction: What is the name of the 2007 focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction?

Output: American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2007 focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction?. ### Response: American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What is the acronym for the American Heart Association Task Force on Practice Guidelines?

Output: American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American Heart Association Task Force on Practice Guidelines?. ### Response: American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery.


Instruction: What are the 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction?

Output: ACC/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction?. ### Response: ACC/AHA.


Instruction: When will the ACC/AHA 2007 guidelines be released?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the ACC/AHA 2007 guidelines be released?. ### Response: April 28, 2023.


Instruction: What are the implications for policy and intervention strate-gies?

Output: populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the implications for policy and intervention strate-gies?. ### Response: populations.


Instruction: What is the prevalence of central obesity among adults with normal BMI and its association with metabolic diseases in northeast China?

Output: Prevalence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of central obesity among adults with normal BMI and its association with metabolic diseases in northeast China?. ### Response: Prevalence.


Instruction: What can remove bivalirudin or argatroban?

Output: e36S Parenteral Anticoagulants Hemodialysis or hemoperfusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can remove bivalirudin or argatroban?. ### Response: e36S Parenteral Anticoagulants Hemodialysis or hemoperfusion.


Instruction: What can clear hirudin using high-flux dialysis membranes?

Output: Dialysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can clear hirudin using high-flux dialysis membranes?. ### Response: Dialysis.


Instruction: Who oversaw the development of this article?

Output: Dr Garcia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who oversaw the development of this article?. ### Response: Dr Garcia.


Instruction: Dr Garcia contributed as a Topic Editor. Dr Baglin contributed as what?

Output: panelist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dr Garcia contributed as a Topic Editor. Dr Baglin contributed as what?. ### Response: panelist.


Instruction: Dr Weitz contributed as who?

Output: panelist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dr Weitz contributed as who?. ### Response: panelist.


Instruction: What did Dr Samama contribute?

Output: as a panelist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Dr Samama contribute?. ### Response: as a panelist.


Instruction: Who contributed as a panelist?

Output: Dr Samama

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who contributed as a panelist?. ### Response: Dr Samama.


Instruction: Who reported to CHEST the following confli cts of interest?

Output: the authors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reported to CHEST the following confli cts of interest?. ### Response: the authors.


Instruction: Who has received honoraria for lectures or consulting from Bayer Healthcare, Johnson & Johnson, Bristol-Myers Squibb, and sanofi-aventis?

Output: Dr Samama

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has received honoraria for lectures or consulting from Bayer Healthcare, Johnson & Johnson, Bristol-Myers Squibb, and sanofi-aventis?. ### Response: Dr Samama.


Instruction: Who has served on a steering committee for Daiichi-Sankyo?

Output: Boehringer Ingelheim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has served on a steering committee for Daiichi-Sankyo?. ### Response: Boehringer Ingelheim.


Instruction: Who was on a steering committee for Daiichi-Sankyo?

Output: Dr Samama

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was on a steering committee for Daiichi-Sankyo?. ### Response: Dr Samama.


Instruction: Who reported that no potential confl icts of interest exist with any companies/organizations whose products or services may be dis-cussed in this article?

Output: Dr Baglin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reported that no potential confl icts of interest exist with any companies/organizations whose products or services may be dis-cussed in this article?. ### Response: Dr Baglin.


Instruction: Who played no role in the development of the guidelines?

Output: The sponsors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who played no role in the development of the guidelines?. ### Response: The sponsors.


Instruction: Sponsoring organizations are not allowed what?

Output: prepublication access

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sponsoring organizations are not allowed what?. ### Response: prepublication access.


Instruction: Who are blinded to the funding sources?

Output: the chair, and members of the Health & Science Policy Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who are blinded to the funding sources?. ### Response: the chair, and members of the Health & Science Policy Committee.


Instruction: Where are further details on the Confl ict of Interest Policy available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are further details on the Confl ict of Interest Policy available?. ### Response: http://chestnet.org.


Instruction: Who endorses this guideline?

Output: American Association for Clinical Chemistry, the American College of Clin-ical Pharmacy, the American Society of Health-System Pharma-cists, the American Society of Hematology, and the International Society of Thrombosis and Hematosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who endorses this guideline?. ### Response: American Association for Clinical Chemistry, the American College of Clin-ical Pharmacy, the American Society of Health-System Pharma-cists, the American Society of Hematology, and the International Society of Thrombosis and Hematosis.


Instruction: The American College of Clin-ical Pharmacy, the American Society of Health-System Pharma-cists, and the International Society of Thrombosis and Hematosis are examples of what?

Output: This guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The American College of Clin-ical Pharmacy, the American Society of Health-System Pharma-cists, and the International Society of Thrombosis and Hematosis are examples of what?. ### Response: This guideline.


Instruction: What is the thromboplastic action of cephalin?

Output: inhibition of blood clotting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the thromboplastic action of cephalin?. ### Response: inhibition of blood clotting.


Instruction: When was the Am J Physiol. 41 : 250-257?

Output: 1916

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Physiol. 41 : 250-257?. ### Response: 1916.


Instruction: What does heparin prevent the conversion of into thrombin?

Output: pro-thrombin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does heparin prevent the conversion of into thrombin?. ### Response: pro-thrombin.


Instruction: What is the name of the unidentifiable substance that acts in conjunction with hisparin to prevent?

Output: inhibition of blood clotting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the unidentifiable substance that acts in conjunction with hisparin to prevent?. ### Response: inhibition of blood clotting.


Instruction: When was the Am J Physiol published?

Output: 1916

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Physiol published?. ### Response: 1916.


Instruction: What year was J Physiol published?

Output: 1916

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was J Physiol published?. ### Response: 1916.


Instruction: What was the name of the journal in 1939?

Output: Am J Physiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the journal in 1939?. ### Response: Am J Physiol.


Instruction: How was antithrombin 3 prepared?

Output: disc electrophoresis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was antithrombin 3 prepared?. ### Response: disc electrophoresis.


Instruction: By what method was electrophoresis performed?

Output: disc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: By what method was electrophoresis performed?. ### Response: disc.


Instruction: What was the total number of disc electrophoretics performed in 1968?

Output: 89 - 91

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the total number of disc electrophoretics performed in 1968?. ### Response: 89 - 91.


Instruction: In what year was Scand J Clin Lab Invest published?

Output: 1968

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was Scand J Clin Lab Invest published?. ### Response: 1968.


Instruction: What is the structure of the antithrombin-binding site in hep-arin?

Output: Structure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the structure of the antithrombin-binding site in hep-arin?. ### Response: Structure.


Instruction: When did Proc Natl Acad Sci U S A publish?

Output: 1979

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Proc Natl Acad Sci U S A publish?. ### Response: 1979.


Instruction: What year was Acad Sci U S A published?

Output: 1979

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Acad Sci U S A published?. ### Response: 1979.


Instruction: How many publications were published in 1979?

Output: 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many publications were published in 1979?. ### Response: 7.


Instruction: What is the name of the journal that published 76 ( 7 ): 3198-3202?

Output: Proc Natl Acad Sci U S A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published 76 ( 7 ): 3198-3202?. ### Response: Proc Natl Acad Sci U S A.


Instruction: What mechanism is activated in unstable angina and myocar-dial infarction?

Output: coagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What mechanism is activated in unstable angina and myocar-dial infarction?. ### Response: coagulation.


Instruction: When was the Circulation. 90 ( 1 ): 61-68?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation. 90 ( 1 ): 61-68?. ### Response: 1994.


Instruction: What are not A V node dependent?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are not A V node dependent?. ### Response: Circulation.


Instruction: What is crucial to distinguish VT from SVT with aberrant conduction, pre-existing bundle-branch block, or pre-excitation?

Output: if the QRS duration is >120 ms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is crucial to distinguish VT from SVT with aberrant conduction, pre-existing bundle-branch block, or pre-excitation?. ### Response: if the QRS duration is >120 ms.


Instruction: What may the administration of verapamil or diltiazem for treatment of VT or AF lead to?

Output: hemodynamic compromise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may the administration of verapamil or diltiazem for treatment of VT or AF lead to?. ### Response: hemodynamic compromise.


Instruction: What may accelerate the ventricular rate and lead to ventricular fibrillation?

Output: the administration of verapamil or diltiazem

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may accelerate the ventricular rate and lead to ventricular fibrillation?. ### Response: the administration of verapamil or diltiazem.


Instruction: What is recommended for acute treatment in patients with regular SVT?

Output: Vagal maneuvers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for acute treatment in patients with regular SVT?. ### Response: Vagal maneuvers.


Instruction: What are Valsalva and carotid sinus massage recommended for?

Output: acute conversion of SVT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Valsalva and carotid sinus massage recommended for?. ### Response: acute conversion of SVT.


Instruction: What should be the first-line intervention to terminate SVT?

Output: vagal maneuvers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the first-line intervention to terminate SVT?. ### Response: vagal maneuvers.


Instruction: Where should these maneuvers be performed?

Output: with the patient in the supine position

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where should these maneuvers be performed?. ### Response: with the patient in the supine position.


Instruction: What will not be effective if the rhythm does not involve the AV node?

Output: Vagal maneuvers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will not be effective if the rhythm does not involve the AV node?. ### Response: Vagal maneuvers.


Instruction: There is no “gold standard” for what?

Output: proper Valsalva maneuver technique

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no “gold standard” for what?. ### Response: proper Valsalva maneuver technique.


Instruction: How long does the patient bear down against a closed glottis?

Output: 10 to 30 seconds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does the patient bear down against a closed glottis?. ### Response: 10 to 30 seconds.


Instruction: What is performed when the patient raises intrathoracic pressure?

Output: bearing down against a closed glottis for 10 to 30 seconds, equivalent to at least 30 mm Hg to 40 mm Hg.82,84 Carotid massage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed when the patient raises intrathoracic pressure?. ### Response: bearing down against a closed glottis for 10 to 30 seconds, equivalent to at least 30 mm Hg to 40 mm Hg.82,84 Carotid massage.


Instruction: How long is the Valsalva maneuver?

Output: 10 to 30 seconds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the Valsalva maneuver?. ### Response: 10 to 30 seconds.


Instruction: What is performed after absence of bruit has been confirmed by auscultation?

Output: Carotid massage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed after absence of bruit has been confirmed by auscultation?. ### Response: Carotid massage.


Instruction: How long does steady pressure over the right or left carotid sinus last?

Output: 5 to 10 seconds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does steady pressure over the right or left carotid sinus last?. ### Response: 5 to 10 seconds.


Instruction: What is another vagal maneuver based on the classic diving reflex?

Output: applying an ice-cold, wet towel to the face

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another vagal maneuver based on the classic diving reflex?. ### Response: applying an ice-cold, wet towel to the face.


Instruction: What does the classic diving reflex consist of applying to the face85?

Output: ice-cold, wet towel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the classic diving reflex consist of applying to the face85?. ### Response: ice-cold, wet towel.


Instruction: What has proved effective in a laboratory setting?

Output: facial immersion in water

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has proved effective in a laboratory setting?. ### Response: facial immersion in water.


Instruction: How many patients with SVT were involved in one study that showed that Valsalva was more successful than carotid sinus massage?

Output: 148

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with SVT were involved in one study that showed that Valsalva was more successful than carotid sinus massage?. ### Response: 148.


Instruction: What was more successful than carotid sinus massage?

Output: Valsalva

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was more successful than carotid sinus massage?. ### Response: Valsalva.


Instruction: What was the overall success rate of Valsalva?

Output: 27.7%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall success rate of Valsalva?. ### Response: 27.7%..


Instruction: The practice of applying pressure to the eyeball has been abandoned.

Output: potentially dangerous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The practice of applying pressure to the eyeball has been abandoned.. ### Response: potentially dangerous.


Instruction: What is recommended for acute treatment?

Output: Vagal maneuvers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for acute treatment?. ### Response: Vagal maneuvers.


Instruction: What has been shown in nonrandomized trials in the emergency department or prehospital setting to effectively terminate SVT that is due to AVNRT?

Output: Adenosine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown in nonrandomized trials in the emergency department or prehospital setting to effectively terminate SVT that is due to AVNRT?. ### Response: Adenosine.


Instruction: What are the success rates of AVNRT and AVRT?

Output: 78% to 96%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the success rates of AVNRT and AVRT?. ### Response: 78% to 96%..


Instruction: What are some side effects that patients may experience?

Output: chest discomfort, shortness of breath, and flushing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some side effects that patients may experience?. ### Response: chest discomfort, shortness of breath, and flushing.


Instruction: Why are serious adverse effects rare?

Output: because of the drug’s very short half-life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are serious adverse effects rare?. ### Response: because of the drug’s very short half-life.