Instruction: Outcomes were similar in men and women in both the CEA and medical management groups.

Output: 427

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Outcomes were similar in men and women in both the CEA and medical management groups.. ### Response: 427.


Instruction: Who is the Director of Outcomes Research at MidAmerica HeartInstitute of St. Luke’sHospital?

Output: John A.Spertus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of Outcomes Research at MidAmerica HeartInstitute of St. Luke’sHospital?. ### Response: John A.Spertus.


Instruction: What is the name of the professor of general medicine at the University ofPennsylvania?

Output: Solomon Katz

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of general medicine at the University ofPennsylvania?. ### Response: Solomon Katz.


Instruction: What table represents the relationships of committee members with industry and other entities that were reported by authors?

Output: Appendix 1. ContinuedCommitteeMember Employment Consultant Speaker’s Bureau

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What table represents the relationships of committee members with industry and other entities that were reported by authors?. ### Response: Appendix 1. ContinuedCommitteeMember Employment Consultant Speaker’s Bureau.


Instruction: What does not necessarily reflect relationships with industry at the time of publication?

Output: The table

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not necessarily reflect relationships with industry at the time of publication?. ### Response: The table.


Instruction: What is deemed to have a significant interest in a business if the interest represents ownership of /H113505% of the voting stock or share of the business entity?

Output: A person

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is deemed to have a significant interest in a business if the interest represents ownership of /H113505% of the voting stock or share of the business entity?. ### Response: A person.


Instruction: How much of the person's gross income did the business entity receive in the previous year?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the person's gross income did the business entity receive in the previous year?. ### Response: 5%.


Instruction: What is considered to be a relationship between a business entity and the person?

Output: modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered to be a relationship between a business entity and the person?. ### Response: modest.


Instruction: What is a relationship considered to be if it is less than significant under the preceding definition?

Output: modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if it is less than significant under the preceding definition?. ### Response: modest.


Instruction: What are relationships in this table modest unless otherwise noted?

Output: less than significant under the preceding definition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are relationships in this table modest unless otherwise noted?. ### Response: less than significant under the preceding definition.


Instruction: What do sectionnumbers apply to?

Output: the full-text guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do sectionnumbers apply to?. ### Response: the full-text guideline.


Instruction: What applies to the full-text guideline?

Output: Sectionnumbers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What applies to the full-text guideline?. ### Response: Sectionnumbers.


Instruction: When was the guideline developed?

Output: during the transition i n RWI policy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the guideline developed?. ### Response: during the transition i n RWI policy.


Instruction: What indicates cardiovascular?

Output: CV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates cardiovascular?. ### Response: CV.


Instruction: What indicates data safety and monitoring board?

Output: DSMB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates data safety and monitoring board?. ### Response: DSMB.


Instruction: How long before the guideline was finalized?

Output: H1102224 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before the guideline was finalized?. ### Response: H1102224 months.


Instruction: What is the Seattle Angina Questionnaire?

Output: SAQ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Seattle Angina Questionnaire?. ### Response: SAQ.


Instruction: Who is the Official Reviewer—ACCF Board of Trustees?

Output: Ralph G. Brindis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Official Reviewer—ACCF Board of Trustees?. ### Response: Ralph G. Brindis.


Instruction: Who is the official reviewer of Brindis?

Output: Timothy D.Henry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the official reviewer of Brindis?. ### Response: Timothy D.Henry.


Instruction: What is the name of the board of Trustees that reviewed Brindi's products?

Output: ACCF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the board of Trustees that reviewed Brindi's products?. ### Response: ACCF.


Instruction: Who is a board member of the AHA?

Output: Timothy D.Henry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a board member of the AHA?. ### Response: Timothy D.Henry.


Instruction: What is the name of the molecular autopsy series that investigated drownings and cardiac channelopathies?

Output: Tester DJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the molecular autopsy series that investigated drownings and cardiac channelopathies?. ### Response: Tester DJ.


Instruction: What are the names of the variants of KCNQ1, KCNH2, KCNE1, and Tzimas I?

Output: Zingraf JC, Bajanowski T, et al. The role of known variants of KCNQ1, KCNH2, KCNE1, SCN5A, and NOS1AP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the variants of KCNQ1, KCNH2, KCNE1, and Tzimas I?. ### Response: Zingraf JC, Bajanowski T, et al. The role of known variants of KCNQ1, KCNH2, KCNE1, SCN5A, and NOS1AP.


Instruction: How many ethnically diverse sudden unexplained deaths did Wang D, Shah KR, Um SY, et al. Cardiac channelopathy testing in 274 unexpected deaths?

Output: 274

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ethnically diverse sudden unexplained deaths did Wang D, Shah KR, Um SY, et al. Cardiac channelopathy testing in 274 unexpected deaths?. ### Response: 274.


Instruction: Forensic Sci Int. 2014;237:90–9.

Output: Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Forensic Sci Int. 2014;237:90–9.. ### Response: Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths.


Instruction: What is true idiopathic ventricular fibrillation in out-of-hospital cardiac arrest survivors in the Swiss Canton Ticino: prevalence, clinical features, and long-term follow-up?

Output: Conte G

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is true idiopathic ventricular fibrillation in out-of-hospital cardiac arrest survivors in the Swiss Canton Ticino: prevalence, clinical features, and long-term follow-up?. ### Response: Conte G.


Instruction: What is frommeyer G, Dechering DG, Kochhauser S, et al.?

Output: Long-time “real-life” performance of the subcutaneous ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is frommeyer G, Dechering DG, Kochhauser S, et al.?. ### Response: Long-time “real-life” performance of the subcutaneous ICD.


Instruction: What is the name of the subcutaneous ICD in patients with electri-cal heart disease or idiopathic ventricular fibrillation?

Output: Long-time “real-life” performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the subcutaneous ICD in patients with electri-cal heart disease or idiopathic ventricular fibrillation?. ### Response: Long-time “real-life” performance.


Instruction: When did the J Interv Card Electrophysiol. 2016 issue 47:185–8?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Interv Card Electrophysiol. 2016 issue 47:185–8?. ### Response: 2016.


Instruction: What was the title of the study published in 2002?

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the study published in 2002?. ### Response: Lancet.


Instruction: What is idiopathic ventricular fibrillation?

Output: Malignant entity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is idiopathic ventricular fibrillation?. ### Response: Malignant entity.


Instruction: What is the name of the new electrocardiographic entity in the torsade de pointes?

Output: Leenhardt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the new electrocardiographic entity in the torsade de pointes?. ### Response: Leenhardt.


Instruction: What is the name of the new electrocardiographic entity in the spectrum of idiopathic ventricular tachyarrhythmias?

Output: Leenhardt A, Glaser E, Burguera M, et al. Short-coupled variant of torsade de pointes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the new electrocardiographic entity in the spectrum of idiopathic ventricular tachyarrhythmias?. ### Response: Leenhardt A, Glaser E, Burguera M, et al. Short-coupled variant of torsade de pointes.


Instruction: When did Circulation.89:206–15. S8.4-14.

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation.89:206–15. S8.4-14.. ### Response: 1994.


Instruction: What is the name of the syndrome that affects children with long QT syndrome?

Output: idiopathic ventricular tachyarrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the syndrome that affects children with long QT syndrome?. ### Response: idiopathic ventricular tachyarrhythmias.


Instruction: What are the names of the children who have a risk of cardiac disease and observations on lack of potential predictors by clinical history?

Output: Miyake CY, Motonaga KS, Fischer-Colbrie ME

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the children who have a risk of cardiac disease and observations on lack of potential predictors by clinical history?. ### Response: Miyake CY, Motonaga KS, Fischer-Colbrie ME.


Instruction: What is one of the potential predictors by clinical history among children presenting for cardiac evaluation of mid-exertional syncope?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the potential predictors by clinical history among children presenting for cardiac evaluation of mid-exertional syncope?. ### Response: heart failure.


Instruction: What is the name of the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)?

Output: S8.4-17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)?. ### Response: S8.4-17.


Instruction: What is SCD-HeFT?

Output: Sudden Cardiac Death in Heart Failure Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SCD-HeFT?. ### Response: Sudden Cardiac Death in Heart Failure Trial.


Instruction: What is the acronym for Heart Failure Trial?

Output: Sudden Cardiac Death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Heart Failure Trial?. ### Response: Sudden Cardiac Death.


Instruction: When was the Am Heart J 156:1196–200?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am Heart J 156:1196–200?. ### Response: 2008.


Instruction: Who is Winkel BG, Yuan L, Olesen MS?

Output: Winkel BG, Yuan L, Olesen MS, et al. The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Winkel BG, Yuan L, Olesen MS?. ### Response: Winkel BG, Yuan L, Olesen MS, et al. The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome.


Instruction: What is a malignant entity of idiopathic ventricular fibrillation and polymorphic ventricular tachycardia initiated by premature extrasystoles originating from the right ventricu-lar outflow tract?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a malignant entity of idiopathic ventricular fibrillation and polymorphic ventricular tachycardia initiated by premature extrasystoles originating from the right ventricu-lar outflow tract?. ### Response: heart failure.


Instruction: What is Sadek MM, Benhayon D, Sureddi R, et al?

Output: Idiopathic ventricular arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Sadek MM, Benhayon D, Sureddi R, et al?. ### Response: Idiopathic ventricular arrhythmias.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227?. ### Response: Otto et al.


Instruction: What are the Referenced studies that support the recommendations summarized in?

Output: Online Data Supplement 31.COR LOE Recommendations2a B-R1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Referenced studies that support the recommendations summarized in?. ### Response: Online Data Supplement 31.COR LOE Recommendations2a B-R1.


Instruction: What is TEER reasonable in patients with appropriate anatomy as defined on TEE?

Output: chronic severe secondary MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TEER reasonable in patients with appropriate anatomy as defined on TEE?. ### Response: chronic severe secondary MR.


Instruction: What is the LVEF 50%?

Output: ≥50%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LVEF 50%?. ### Response: ≥50%).


Instruction: What is reasonable in patients with appropriate anatomy as defined on TEE and with LVEF between 20% and 50%, LVESD 70 mm Hg.1–82a B-NR2?

Output: TEER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in patients with appropriate anatomy as defined on TEE and with LVEF between 20% and 50%, LVESD 70 mm Hg.1–82a B-NR2?. ### Response: TEER.


Instruction: In patients with severe secondary MR (Stages C and D), what is reasonable when CABG is undertaken?

Output: mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with severe secondary MR (Stages C and D), what is reasonable when CABG is undertaken?. ### Response: mitral valve surgery.


Instruction: What is reasonable when CABG is undertaken for the treatment of myocardial ischemia?

Output: mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable when CABG is undertaken for the treatment of myocardial ischemia?. ### Response: mitral valve surgery.


Instruction: What type of surgery is reasonable in patients with chronic severe secondary MR from atrial annular dilation?

Output: mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery is reasonable in patients with chronic severe secondary MR from atrial annular dilation?. ### Response: mitral valve surgery.


Instruction: What type of surgery may be considered in patients with HF and associated AF?

Output: mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery may be considered in patients with HF and associated AF?. ### Response: mitral valve surgery.


Instruction: In patients with chronic severe secondary MR related to LV systolic dysfunction who have persistent severe symptoms, what type of valve surgery is considered?

Output: mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with chronic severe secondary MR related to LV systolic dysfunction who have persistent severe symptoms, what type of valve surgery is considered?. ### Response: mitral.


Instruction: What type of valve surgery may be considered in patients with persistent severe symptoms?

Output: mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve surgery may be considered in patients with persistent severe symptoms?. ### Response: mitral.


Instruction: What is the stage D of LV systolic dysfunction?

Output: LVEF <50%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the stage D of LV systolic dysfunction?. ### Response: LVEF <50%).


Instruction: What percentage of dysfunction is present in Stage D patients undergoing mitral valve surgery?

Output: <50%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of dysfunction is present in Stage D patients undergoing mitral valve surgery?. ### Response: <50%).


Instruction: What type of valve replacement may be reasonable to choose over downsized annuloplasty repair?

Output: mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve replacement may be reasonable to choose over downsized annuloplasty repair?. ### Response: mitral.


Instruction: What is indicated to improve symptoms and pro-long life in a select subset of patients with chronic se-vere secondary MR, LV systolic dysfunction, and persis-tent severe symptoms?

Output: Mitral TEER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated to improve symptoms and pro-long life in a select subset of patients with chronic se-vere secondary MR, LV systolic dysfunction, and persis-tent severe symptoms?. ### Response: Mitral TEER.


Instruction: Surgery may improve symptoms in patients with what?

Output: se-vere secondary MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Surgery may improve symptoms in patients with what?. ### Response: se-vere secondary MR.


Instruction: What is preferred over repair?

Output: mitral valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preferred over repair?. ### Response: mitral valve replacement.


Instruction: What may a subset of patients with severe MR attributable to AF benefit from?

Output: mitral valve surgery and concomitant atrial maze procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may a subset of patients with severe MR attributable to AF benefit from?. ### Response: mitral valve surgery and concomitant atrial maze procedure.


Instruction: The COAPT trial demonstrated improvement in sur-vival, hospitalization, symptoms, and what else?

Output: quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The COAPT trial demonstrated improvement in sur-vival, hospitalization, symptoms, and what else?. ### Response: quality of life.


Instruction: What is MITRA-FR?

Output: Multicentre Randomized Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MITRA-FR?. ### Response: Multicentre Randomized Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation.


Instruction: What type of GDMT did patients with persistent symptoms receive?

Output: Stage D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of GDMT did patients with persistent symptoms receive?. ### Response: Stage D.


Instruction: What is the name of the device used to repair patients with severe secondary mitral regurgitation?

Output: Percutaneous Mitral Valve Repair MitraClip Device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the device used to repair patients with severe secondary mitral regurgitation?. ### Response: Percutaneous Mitral Valve Repair MitraClip Device.


Instruction: Patients with greater degrees of LV enlargement were enrolled with what?

Output: MITRA-FR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with greater degrees of LV enlargement were enrolled with what?. ### Response: MITRA-FR.


Instruction: What is the name of the person who is a content reviewer for the ACC/AHA Task Force on Practice Guidelines?

Output: Richard J.  Kovacs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who is a content reviewer for the ACC/AHA Task Force on Practice Guidelines?. ### Response: Richard J.  Kovacs.


Instruction: Who is the Chief, Division of Cardiothoracic Surgery at Emory University School of Medicine?

Output: Stephen J.  Lahey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chief, Division of Cardiothoracic Surgery at Emory University School of Medicine?. ### Response: Stephen J.  Lahey.


Instruction: Who is the Professor of Medicine at St. Sinai Medical Center?

Output: AstraZeneca

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Professor of Medicine at St. Sinai Medical Center?. ### Response: AstraZeneca.


Instruction: What is the name of the professor of medicine at Stanford University School of Medicine?

Output: Professor  of Health Research and Policy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at Stanford University School of Medicine?. ### Response: Professor  of Health Research and Policy.


Instruction: Where is Mark Hlatky from?

Output: Stanford University School  of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Mark Hlatky from?. ### Response: Stanford University School  of Medicine.


Instruction: Who is the professor of Health Research and Policy at Stanford University School of Medicine?

Output: Mark A.  Hlatky

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of Health Research and Policy at Stanford University School of Medicine?. ### Response: Mark A.  Hlatky.


Instruction: What is the name of the professor at Rush University Medical Center?

Output: Internal Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor at Rush University Medical Center?. ### Response: Internal Medicine.


Instruction: Who is a professor at the Crannert Institute of Cardiology?

Output: Richard J.  Kovacs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a professor at the Crannert Institute of Cardiology?. ### Response: Richard J.  Kovacs.


Instruction: How many professors are in the ACC/AHA Task Force on Practice Guidelines?

Output: None None None

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many professors are in the ACC/AHA Task Force on Practice Guidelines?. ### Response: None None None.


Instruction: What is the name of the ACC/AHA Task Force on Practice Guidelines?

Output: Content Reviewer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACC/AHA Task Force on Practice Guidelines?. ### Response: Content Reviewer.


Instruction: Who is the professor of clinical medicine at the Krannert Institute of Cardiology?

Output: Richard J.  Kovacs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of clinical medicine at the Krannert Institute of Cardiology?. ### Response: Richard J.  Kovacs.


Instruction: What is Eli Lilly's profession?

Output: Consultant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Eli Lilly's profession?. ### Response: Consultant.


Instruction: Who is the Director of the Baylor Health Care System?

Output: Michael J.  Mack

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of the Baylor Health Care System?. ### Response: Michael J.  Mack.


Instruction: What is the name of the professor of medicine at Duke Clinical Research Institute?

Output: Daniel B.  Mark

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at Duke Clinical Research Institute?. ### Response: Daniel B.  Mark.


Instruction: Which company is the director of Vanderbilt University Medical Center?

Output: AstraZeneca

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which company is the director of Vanderbilt University Medical Center?. ### Response: AstraZeneca.


Instruction: Who is the Director of Vanderbilt Chest Pain Center?

Output: Vanderbilt University  Medical Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of Vanderbilt Chest Pain Center?. ### Response: Vanderbilt University  Medical Center.


Instruction: What is the name of the person who is the President of Saudi Heart Association?

Output: Hani K.  Najm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who is the President of Saudi Heart Association?. ### Response: Hani K.  Najm.


Instruction: Where is Kristin Newby from?

Output: Duke University Medical Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Kristin Newby from?. ### Response: Duke University Medical Center.


Instruction: Who is the Director of Clinical Cardiology at Harvard Medical School?

Output: Brigham and Women’s  Hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of Clinical Cardiology at Harvard Medical School?. ### Response: Brigham and Women’s  Hospital.


Instruction: What is the name of the medical school that is the Professor of Medicine at Harvard?

Output: Harvard Medical School

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the medical school that is the Professor of Medicine at Harvard?. ### Response: Harvard Medical School.


Instruction: When was Lantheus Medical downloaded from http://ahajournals.org?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Lantheus Medical downloaded from http://ahajournals.org?. ### Response: May 1, 2023.


Instruction: What is the relationship between insulin and carotid athero-sclerosis in the general population?

Output: concentrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between insulin and carotid athero-sclerosis in the general population?. ### Response: concentrations.


Instruction: When did the Bruneck Study take place?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Bruneck Study take place?. ### Response: 1997.


Instruction: What is the association between insulin and carotid wall thickness?

Output: concentrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between insulin and carotid wall thickness?. ### Response: concentrations.


Instruction: When did the Insulin Resistance Atherosclerosis Study begin?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Insulin Resistance Atherosclerosis Study begin?. ### Response: 1998.


Instruction: What are important predictors of stroke?

Output: abnormal glucose metabolism and insulin resistance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are important predictors of stroke?. ### Response: abnormal glucose metabolism and insulin resistance.


Instruction: What are important predictors of stroke in elderly subjects?

Output: Non-insulin-dependent diabetes and its metabolic control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are important predictors of stroke in elderly subjects?. ### Response: Non-insulin-dependent diabetes and its metabolic control.


Instruction: What is a risk factor for stroke in a cohort of non-institutionalised people aged 70 years?

Output: Impaired glucose tolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for stroke in a cohort of non-institutionalised people aged 70 years?. ### Response: Impaired glucose tolerance.


Instruction: How old is the average age of a person who has a stroke?

Output: 640

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is the average age of a person who has a stroke?. ### Response: 640.


Instruction: What is the age range of people who have strokes?

Output: 640

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age range of people who have strokes?. ### Response: 640.


Instruction: How old are the people who had strokes that had a high proinsulin level?

Output: 640

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are the people who had strokes that had a high proinsulin level?. ### Response: 640.


Instruction: What is a risk factor for stroke in a Japanese sample?

Output: Impaired glucose tolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for stroke in a Japanese sample?. ### Response: Impaired glucose tolerance.


Instruction: What is the Funagata study?

Output: Impaired glucose tolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Funagata study?. ### Response: Impaired glucose tolerance.


Instruction: How long did the Helsinki Policemen Study follow-up?

Output: 22-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Helsinki Policemen Study follow-up?. ### Response: 22-year.


Instruction: What was the duration of the Helsinki policemen study?

Output: 22-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the duration of the Helsinki policemen study?. ### Response: 22-year.


Instruction: How many years did the Finnish Policemen study follow up on the risk of stroke in healthy middle aged men?

Output: 22

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years did the Finnish Policemen study follow up on the risk of stroke in healthy middle aged men?. ### Response: 22.


Instruction: What does Impaired glucose tolerance increase in nondiabetic patients with transient ischemic attack?

Output: stroke risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Impaired glucose tolerance increase in nondiabetic patients with transient ischemic attack?. ### Response: stroke risk.


Instruction: What does Stroke. 2006;37:1413-1417?

Output: Impaired glucose tolerance increases stroke risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Stroke. 2006;37:1413-1417?. ### Response: Impaired glucose tolerance increases stroke risk.


Instruction: What predicts incident stroke in elderly people in Finland?

Output: The metabolic syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts incident stroke in elderly people in Finland?. ### Response: The metabolic syndrome.


Instruction: What does the metabolic syndrome predict?

Output: incident stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the metabolic syndrome predict?. ### Response: incident stroke.


Instruction: How long did the follow-up study in Finland last?

Output: 14-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the follow-up study in Finland last?. ### Response: 14-year.


Instruction: IJ, Shaper AG. Nonfasting serum glucose and insulin concentrations and the risk of stroke. Stroke. 1999;30:1780–1786. 639. Urabe T, Watada H, Okuma Y, Tanaka R, Miyamoto N, Hattori N, Kawamori R. Prevalence of abnormal glucose metabolism and insulin resistance among subtypes of what?

Output: Wannamethee SG, Perry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: IJ, Shaper AG. Nonfasting serum glucose and insulin concentrations and the risk of stroke. Stroke. 1999;30:1780–1786. 639. Urabe T, Watada H, Okuma Y, Tanaka R, Miyamoto N, Hattori N, Kawamori R. Prevalence of abnormal glucose metabolism and insulin resistance among subtypes of what?. ### Response: Wannamethee SG, Perry.


Instruction: What is the name of the study that investigated the association between abnormal glucose metabolism and insulin resistance in Japanese patients?

Output: EpiDREAM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the association between abnormal glucose metabolism and insulin resistance in Japanese patients?. ### Response: EpiDREAM.


Instruction: How many patients had ischemic stroke in Japan in 2009?

Output: 640

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had ischemic stroke in Japan in 2009?. ### Response: 640.


Instruction: What are the names of the investigators involved in the study?

Output: Anand SS, Dagenais GR, Mohan V , Diaz R, Probstfield J, Freeman R, Shaw J, Lanas F, Avezum A, Budaj A, Jung H, Desai D, Bosch J, Yusuf S, Gerstein HC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the investigators involved in the study?. ### Response: Anand SS, Dagenais GR, Mohan V , Diaz R, Probstfield J, Freeman R, Shaw J, Lanas F, Avezum A, Budaj A, Jung H, Desai D, Bosch J, Yusuf S, Gerstein HC.


Instruction: Who are EpiDREAM Investigators?

Output: Anand SS, Dagenais GR, Mohan V , Diaz R, Probstfield J, Freeman R, Shaw J, Lanas F, Avezum A, Budaj A, Jung H, Desai D, Bosch J, Yusuf S, Gerstein HC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who are EpiDREAM Investigators?. ### Response: Anand SS, Dagenais GR, Mohan V , Diaz R, Probstfield J, Freeman R, Shaw J, Lanas F, Avezum A, Budaj A, Jung H, Desai D, Bosch J, Yusuf S, Gerstein HC.


Instruction: What is associated with cardiovascular disease and death in an international cohort of normal glycaemic men and women?

Output: Glucose levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with cardiovascular disease and death in an international cohort of normal glycaemic men and women?. ### Response: Glucose levels.


Instruction: What percentage of the cohort had prediabetes?

Output: 42%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the cohort had prediabetes?. ### Response: 42%.


Instruction: What was the baseline fastingserum glucose >100 mg/dl?

Output: 5.6 mmol/l].

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the baseline fastingserum glucose >100 mg/dl?. ### Response: 5.6 mmol/l]..


Instruction: How many participants were included with CKD?

Output: 4983

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants were included with CKD?. ### Response: 4983.


Instruction: What did post hoc analysis of SPRINT compare participants with and without prediabetes find?

Output: the CV and survival bene ﬁts of intensive SBPreduction ( <120 mm Hg) were similar in the 2 subgroups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did post hoc analysis of SPRINT compare participants with and without prediabetes find?. ### Response: the CV and survival bene ﬁts of intensive SBPreduction ( <120 mm Hg) were similar in the 2 subgroups.


Instruction: What was the CV and survival bene fits of intensive SBPreduction similar in the 2 subgroups?

Output: <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the CV and survival bene fits of intensive SBPreduction similar in the 2 subgroups?. ### Response: <120 mm Hg.


Instruction: Other secondary analyses of what data suggest that intensive SBP lowering is beneficial?

Output: ACCORD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Other secondary analyses of what data suggest that intensive SBP lowering is beneficial?. ### Response: ACCORD.


Instruction: What did a combined post hocanalysis of SPRINT and ACCORD suggest?

Output: similar CVbeneﬁts of intensive BP-lowering therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a combined post hocanalysis of SPRINT and ACCORD suggest?. ### Response: similar CVbeneﬁts of intensive BP-lowering therapy.


Instruction: What was a BP trial but also employed a rather complex study design?

Output: ACCORD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a BP trial but also employed a rather complex study design?. ### Response: ACCORD.


Instruction: How was the trial of glycemiccontrol terminated early?

Output: because of higher all-causemortality with intensive glycemic control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the trial of glycemiccontrol terminated early?. ### Response: because of higher all-causemortality with intensive glycemic control.


Instruction: What was the effect of intensive versus less-intensive BP control?

Output: increased CV death, HF, and MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of intensive versus less-intensive BP control?. ### Response: increased CV death, HF, and MI.


Instruction: What was higher all-causemortality with intensive glycemic control?

Output: 92

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was higher all-causemortality with intensive glycemic control?. ### Response: 92.


Instruction: What was also demonstrated in the CKD subgroup of ACCORD?

Output: adverse ef-fect of intensive glycemic control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was also demonstrated in the CKD subgroup of ACCORD?. ### Response: adverse ef-fect of intensive glycemic control.


Instruction: What did the combined analysis of ACCORD and SPRINT show?

Output: similar CVbeneﬁts of intensive BP-lowering therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the combined analysis of ACCORD and SPRINT show?. ### Response: similar CVbeneﬁts of intensive BP-lowering therapy.


Instruction: What did intensive SBPcontrol increase?

Output: CV death, HF, and MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did intensive SBPcontrol increase?. ### Response: CV death, HF, and MI.


Instruction: How was the combined CV endpoints and onall-cause mortality similar?

Output: similar in the standard glycemia armof ACCORD and in SPRINT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the combined CV endpoints and onall-cause mortality similar?. ### Response: similar in the standard glycemia armof ACCORD and in SPRINT.


Instruction: What increased CV death, HF, and MI in the intensiveglycemia arm?

Output: intensive SBPcontrol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increased CV death, HF, and MI in the intensiveglycemia arm?. ### Response: intensive SBPcontrol.


Instruction: After discontinua-tion of the glycemic intervention, what did these interactions lessen?

Output: increased CV death, HF, and MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After discontinua-tion of the glycemic intervention, what did these interactions lessen?. ### Response: increased CV death, HF, and MI.


Instruction: What did intensive BPcontrol increase in the ACCORD group?

Output: CV death, HF, and MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did intensive BPcontrol increase in the ACCORD group?. ### Response: CV death, HF, and MI.


Instruction: What did intensive BP control provide similar to those seen in SPRINT?

Output: CV bene ﬁts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did intensive BP control provide similar to those seen in SPRINT?. ### Response: CV bene ﬁts.


Instruction: What did a pooled analysis of individual patient data from4983 patients with CKD from AASK, MDRD, ACCORD andSPRINT find?

Output: a non-signi ﬁcant trend to decreased mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a pooled analysis of individual patient data from4983 patients with CKD from AASK, MDRD, ACCORD andSPRINT find?. ### Response: a non-signi ﬁcant trend to decreased mortality.


Instruction: What is the trend to decreased mortality with intensive BP-lowering therapy?

Output: non-signi ﬁcant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the trend to decreased mortality with intensive BP-lowering therapy?. ### Response: non-signi ﬁcant.


Instruction: What is a statistical signifi-cant reduction in mortality in a subgroup with eGFR 60ml/min per 1.73 m2who were not assigned to intensive gly-cemic control?

Output: 125

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a statistical signifi-cant reduction in mortality in a subgroup with eGFR 60ml/min per 1.73 m2who were not assigned to intensive gly-cemic control?. ### Response: 125.


Instruction: What does glycemic control modulate the effects of intensiveBP control on?

Output: CV outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does glycemic control modulate the effects of intensiveBP control on?. ### Response: CV outcomes.


Instruction: What does indirect evidence reduce the certainty of?

Output: bene ﬁts and strength ofrecommendation of targeting SBP <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does indirect evidence reduce the certainty of?. ### Response: bene ﬁts and strength ofrecommendation of targeting SBP <120 mm Hg.


Instruction: What is the name of the journal that was downloaded from http://ahajournals.org on May 3, 2023?

Output: ahajournals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that was downloaded from http://ahajournals.org on May 3, 2023?. ### Response: ahajournals.


Instruction: Who is the chairman of the Merck-Adjudication (Event)Committee*NoneVincent Sorrell University of Arizona None None Lantheus Medical Imaging None None None What is the name of the questionnaire that all reviewers use to report conflicts of interest?

Output: DisclosureQuestionnaire

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the chairman of the Merck-Adjudication (Event)Committee*NoneVincent Sorrell University of Arizona None None Lantheus Medical Imaging None None None What is the name of the questionnaire that all reviewers use to report conflicts of interest?. ### Response: DisclosureQuestionnaire.


Instruction: What does the DisclosureQuestionnaire report on?

Output: conflicts of interest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the DisclosureQuestionnaire report on?. ### Response: conflicts of interest.


Instruction: What is a relationship considered to be if the person receives $10 000 or more during a 12-month period?

Output: significant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if the person receives $10 000 or more during a 12-month period?. ### Response: significant.


Instruction: If the person owns 5% or more of the person's gross income, what is considered a significant relationship?

Output: $10 000 or moreduring any 12-month period

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the person owns 5% or more of the person's gross income, what is considered a significant relationship?. ### Response: $10 000 or moreduring any 12-month period.


Instruction: Who owns 5% or more of the voting stock or share of an entity?

Output: Thomas W.Rooke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who owns 5% or more of the voting stock or share of an entity?. ### Response: Thomas W.Rooke.


Instruction: What is a relationship considered to be if it is less than “significant” under the preceding definition?

Output: modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if it is less than “significant” under the preceding definition?. ### Response: modest.


Instruction: What is the meaning of the term "Modest"?

Output: if it is less than “significant”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the meaning of the term "Modest"?. ### Response: if it is less than “significant”.


Instruction: What is a definition of 'Modest'?

Output: less than “significant”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a definition of 'Modest'?. ### Response: less than “significant”.


Instruction: When was the AHA/ACCF Secondary Prevention: 2011 Update 2467?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the AHA/ACCF Secondary Prevention: 2011 Update 2467?. ### Response: May 1, 2023.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?

Output: treatment of blood cholesterol to reduce atherosclerotic cardio-vascular risk in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?. ### Response: treatment of blood cholesterol to reduce atherosclerotic cardio-vascular risk in adults.


Instruction: What is diabetes a coro-nary risk equivalent?

Output: Systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is diabetes a coro-nary risk equivalent?. ### Response: Systematic review and meta-analysis.


Instruction: What is the name of the 2004 Surgeon General’s Report: The Health Consequences of Smoking?

Output: US Department of Health and Human Services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2004 Surgeon General’s Report: The Health Consequences of Smoking?. ### Response: US Department of Health and Human Services.


Instruction: What is PHS?

Output: US Department of Health and Human Services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PHS?. ### Response: US Department of Health and Human Services.


Instruction: What is the Office on Smoking and Health?

Output: US Department of Health and Human Services PHS, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Office on Smoking and Health?. ### Response: US Department of Health and Human Services PHS, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion.


Instruction: Who is Goldenberg I?

Output: 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Goldenberg I?. ### Response: 33.


Instruction: Bezafibrate Infarction Prevention Study Group. Current smoking, smoking cessation and the risk of sudden cardiac death in patients with coronary artery disease.

Output: General’s Report: The Health Consequences of Smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bezafibrate Infarction Prevention Study Group. Current smoking, smoking cessation and the risk of sudden cardiac death in patients with coronary artery disease.. ### Response: General’s Report: The Health Consequences of Smoking.


Instruction: Arch Intern Med. 2003;163:2301–2305.

Output: General’s Report: The Health Consequences of Smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arch Intern Med. 2003;163:2301–2305.. ### Response: General’s Report: The Health Consequences of Smoking.


Instruction: US Department of Health and Human Services. What is the Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General.

Output: 34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: US Department of Health and Human Services. What is the Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General.. ### Response: 34.


Instruction: Tobacco Smoke: A Report of the Surgeon General.

Output: The Health Consequences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tobacco Smoke: A Report of the Surgeon General.. ### Response: The Health Consequences.


Instruction: Atlanta, GA: US Department of Health and Human Services PHS, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2006.

Output: 35

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atlanta, GA: US Department of Health and Human Services PHS, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2006.. ### Response: 35.


Instruction: How many years of progress did the US Office of the Surgeon General make in reducing the health consequences of smoking?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of progress did the US Office of the Surgeon General make in reducing the health consequences of smoking?. ### Response: 25.


Instruction: What was the name of the report released by the US Department of Health and Human Services in 1989?

Output: Reducing the Health Consequences of Smoking: 25 Years of Progress: A Report of the Surgeon General

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the report released by the US Department of Health and Human Services in 1989?. ### Response: Reducing the Health Consequences of Smoking: 25 Years of Progress: A Report of the Surgeon General.


Instruction: What type of hypertension is caused by excessive smoking?

Output: malignant-phase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypertension is caused by excessive smoking?. ### Response: malignant-phase.


Instruction: What is the name of the group that studies the effects of smoking cessation?

Output: Lung Health Study Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies the effects of smoking cessation?. ### Response: Lung Health Study Research Group.


Instruction: How long does a smoker die?

Output: 14.5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does a smoker die?. ### Response: 14.5-year.


Instruction: How long did a smoking cessation intervention last?

Output: 14.5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did a smoking cessation intervention last?. ### Response: 14.5-year.


Instruction: What was the outcome of a randomized clinical trial?

Output: 14.5-year mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of a randomized clinical trial?. ### Response: 14.5-year mortality.


Instruction: When did obesity increase among US adults?

Output: 1999–2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did obesity increase among US adults?. ### Response: 1999–2008.


Instruction: Who was the author of the study?

Output: Goldenberg I, Jonas M, Tenenbaum A, Boyko V , Matetzky S, Shotan A, Behar S, Reicher-Reiss H; Bezafibrate Infarction Prevention Study Group. Current smoking, smoking cessation, and the risk of sudden cardiac death in patients with coronary artery disease. Arch Intern Med. 2003;163:2301–2305. 34. US Department of Health and Human Services. The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of the study?. ### Response: Goldenberg I, Jonas M, Tenenbaum A, Boyko V , Matetzky S, Shotan A, Behar S, Reicher-Reiss H; Bezafibrate Infarction Prevention Study Group. Current smoking, smoking cessation, and the risk of sudden cardiac death in patients with coronary artery disease. Arch Intern Med. 2003;163:2301–2305. 34. US Department of Health and Human Services. The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General.


Instruction: Where did the study take place?

Output: Atlanta, GA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did the study take place?. ### Response: Atlanta, GA.


Instruction: What is the name of the journal that reviewed the relationship between overweight and hypertension?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that reviewed the relationship between overweight and hypertension?. ### Response: Circulation.


Instruction: What is another name for the disease burden associated with overweight and obesity?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the disease burden associated with overweight and obesity?. ### Response: JAMA.


Instruction: When was the JAMA published?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 2003.


Instruction: What are the determinants of cardiovascular risk?

Output: Overweight and obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the determinants of cardiovascular risk?. ### Response: Overweight and obesity.


Instruction: What is the Framingham experience?

Output: Overweight and obesity as determinants of cardiovascular risk: the Framingham expe-rience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Framingham experience?. ### Response: Overweight and obesity as determinants of cardiovascular risk: the Framingham expe-rience.


Instruction: How many people are overweight and obese?

Output: 41

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people are overweight and obese?. ### Response: 41.


Instruction: What year was diabetes and obesity-related health risk factors studied?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was diabetes and obesity-related health risk factors studied?. ### Response: 2001.


Instruction: What was the name of the journal that published the study in 2003?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the journal that published the study in 2003?. ### Response: JAMA.


Instruction: How did Kotchen TA describe obesity related hypertension?

Output: epidemiology, pathophysiol-ogy, and clinical management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Kotchen TA describe obesity related hypertension?. ### Response: epidemiology, pathophysiol-ogy, and clinical management.


Instruction: When was the study published?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the study published?. ### Response: 2014.


Instruction: What is the name of the reference list for Chronic Heart Failure?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the reference list for Chronic Heart Failure?. ### Response: NICE 2018.


Instruction: Who is the author of this reference list?

Output: NICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of this reference list?. ### Response: NICE.


Instruction: What are the baseline characteristics of patients in the treatment of preserved card iac function heart failure with an aldosterone antagonist trial?

Output: reduced left ventricular ejection fractions and congestive heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the baseline characteristics of patients in the treatment of preserved card iac function heart failure with an aldosterone antagonist trial?. ### Response: reduced left ventricular ejection fractions and congestive heart failure.


Instruction: What is the Circulation: Heart Failure. 2013; 6(2):184 -92 311.

Output: Baseline characteristics of patients in the treatment of preserved card iac function heart failure with an aldosterone antagonist trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Circulation: Heart Failure. 2013; 6(2):184 -92 311.. ### Response: Baseline characteristics of patients in the treatment of preserved card iac function heart failure with an aldosterone antagonist trial.


Instruction: What are renal function, digoxin therapy and heart failure outcomes?

Output: evidence from the dig oxin intervention group trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are renal function, digoxin therapy and heart failure outcomes?. ### Response: evidence from the dig oxin intervention group trial.


Instruction: What did the dig oxin intervention group trial show?

Output: Renal function, digoxin therapy, and heart failure outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the dig oxin intervention group trial show?. ### Response: Renal function, digoxin therapy, and heart failure outcomes.


Instruction: What was the journal of the American Society of Nephrology published in 2004?

Output: 15(8):2195 -203 312

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the journal of the American Society of Nephrology published in 2004?. ### Response: 15(8):2195 -203 312.


Instruction: How did Shochat M, Shotan A, Dahan I treat outpatients with heart failure?

Output: NT -proBNP -guided preemptive treatment of outpatients with chronic heart failure followed in a out hospital clinic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Shochat M, Shotan A, Dahan I treat outpatients with heart failure?. ### Response: NT -proBNP -guided preemptive treatment of outpatients with chronic heart failure followed in a out hospital clinic.


Instruction: What type of study did Simmonds R, Glogowska M, McLachlan S, Cramer H, Sanders T, Johnson R, and Johnson R do in relation to heart failure?

Output: multicentre ethnographic, qualitative study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of study did Simmonds R, Glogowska M, McLachlan S, Cramer H, Sanders T, Johnson R, and Johnson R do in relation to heart failure?. ### Response: multicentre ethnographic, qualitative study.


Instruction: In what year did BMJ Open publish a study on unplanned admissions and the organisational management of heart failure in a multicentre study?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did BMJ Open publish a study on unplanned admissions and the organisational management of heart failure in a multicentre study?. ### Response: 2015.


Instruction: What is a multicentre ethnographic, qualitative study of heart failure?

Output: Unplanned admissions and the organisational management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a multicentre ethnographic, qualitative study of heart failure?. ### Response: Unplanned admissions and the organisational management.


Instruction: What is the name of the randomized trial that examined the effect of nurse management on the quality of care in minority communities?

Output: Solvd Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial that examined the effect of nurse management on the quality of care in minority communities?. ### Response: Solvd Investigators.


Instruction: What is the name of the randomized trial?

Output: Effects of nurse management on the quality of heart failure care in minority communities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial?. ### Response: Effects of nurse management on the quality of heart failure care in minority communities.


Instruction: What is one of the benefits of personalized healthcare for patients with chronic heart failure?

Output: preemptive treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the benefits of personalized healthcare for patients with chronic heart failure?. ### Response: preemptive treatment.


Instruction: What is the educational program called?

Output: Telemedicine for the Heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the educational program called?. ### Response: Telemedicine for the Heart.


Instruction: What is Telemedicine for the Heart?

Output: care and education program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Telemedicine for the Heart?. ### Response: care and education program.


Instruction: When was Telemedicine and e-Health published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Telemedicine and e-Health published?. ### Response: 2012.


Instruction: How did enalapril affect survival in patients with heart failure?

Output: Baseline characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did enalapril affect survival in patients with heart failure?. ### Response: Baseline characteristics.


Instruction: What year did the Journal of Medicine issue 325(5):293 -302 317?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Journal of Medicine issue 325(5):293 -302 317?. ### Response: 1991.


Instruction: What is the name of the randomized clinical trial of enhanced heart failure monitoring using a computer-based telephonic monitoring system?

Output: Soran OZ, Pina IL,  Lamas GA, Kelsey SF, Selzer F, Pilotte J et al. A randomized clinical trial of the clinical effects of enhanced heart failure monitoring using a computer -based telephonic monitoring system in older minorities and women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial of enhanced heart failure monitoring using a computer-based telephonic monitoring system?. ### Response: Soran OZ, Pina IL,  Lamas GA, Kelsey SF, Selzer F, Pilotte J et al. A randomized clinical trial of the clinical effects of enhanced heart failure monitoring using a computer -based telephonic monitoring system in older minorities and women.


Instruction: What is the monitoring system in older minorities and women?

Output: computer -based telephonic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the monitoring system in older minorities and women?. ### Response: computer -based telephonic.


Instruction: When was the Journal of Cardiac Failure published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Journal of Cardiac Failure published?. ### Response: 2012.


Instruction: What was the AHEAD score in acute heart failure?

Output: Long -term risk classification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the AHEAD score in acute heart failure?. ### Response: Long -term risk classification.


Instruction: Where was the International Journal of Cardiology published in 2016?

Output: 202:21 -6 319

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the International Journal of Cardiology published in 2016?. ### Response: 202:21 -6 319.


Instruction: What is the name of the journal that studies heart failure and prognosis in patients with end-stage renal disease treated by hemodialysis?

Output: Health Science Journal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies heart failure and prognosis in patients with end-stage renal disease treated by hemodialysis?. ### Response: Health Science Journal.


Instruction: When was Kidney and Blood Pressure Research published?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Kidney and Blood Pressure Research published?. ### Response: 2007.


Instruction: What did Kidney and Blood Pressure Research do in 2007?

Output: Neurohumoral activity, heart failure and prognosis in patients with end -stage renal disease treated by hemodialysis. Kidney and Blood Pressure Research. 2007; 30(5):347 -57 320

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Kidney and Blood Pressure Research do in 2007?. ### Response: Neurohumoral activity, heart failure and prognosis in patients with end -stage renal disease treated by hemodialysis. Kidney and Blood Pressure Research. 2007; 30(5):347 -57 320.


Instruction: What did Stavrianopoulos T say about the quality of life in patients with heart failure in a district hospital of Greece?

Output: Impact of a nurses -led telephon e intervention program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Stavrianopoulos T say about the quality of life in patients with heart failure in a district hospital of Greece?. ### Response: Impact of a nurses -led telephon e intervention program.


Instruction: When did Health Science Journal publish its 2016 issue?

Output: 2016; 10(4):1 -8 321

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Health Science Journal publish its 2016 issue?. ### Response: 2016; 10(4):1 -8 321.


Instruction: What is the name of the study that investigated exercise capacity and morta lity in patients with ischemic left ventricular dysfunction?

Output: coronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated exercise capacity and morta lity in patients with ischemic left ventricular dysfunction?. ### Response: coronary.


Instruction: How many patients with CKD were included inACCORD?

Output: few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with CKD were included inACCORD?. ### Response: few.


Instruction: What was the mean creatinine in ACCORD patients?

Output: >1.5 mg/dl

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean creatinine in ACCORD patients?. ### Response: >1.5 mg/dl.


Instruction: How much proteinuric were the patients who were excluded fromACCORD because they had a well-preservedeGFR?

Output: >1.5 mg/dl (132mmol/l)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much proteinuric were the patients who were excluded fromACCORD because they had a well-preservedeGFR?. ### Response: >1.5 mg/dl (132mmol/l).


Instruction: What is CKD?

Output: proteinuric with well-preservedeGFR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD?. ### Response: proteinuric with well-preservedeGFR.


Instruction: What was the effect of intensive BP lowering on stroke risk?

Output: there was no statisticalinteraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of intensive BP lowering on stroke risk?. ### Response: there was no statisticalinteraction.


Instruction: When was Kidney International founded?

Output: 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Kidney International founded?. ### Response: 2021.


Instruction: How does the CDU use telehealth, m-health, and e-health to better diagnose and manage HBPMeasure components?

Output: Developing a framework to iteratively and routinely assess ongoing efficacy of different telehealth strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the CDU use telehealth, m-health, and e-health to better diagnose and manage HBPMeasure components?. ### Response: Developing a framework to iteratively and routinely assess ongoing efficacy of different telehealth strategies.


Instruction: What is the DOI of the 2019 AHA/ACC High Blood Pressure Performance and Quality Measures?

Output: 10.1161/HCQ.0000000000000057

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI of the 2019 AHA/ACC High Blood Pressure Performance and Quality Measures?. ### Response: 10.1161/HCQ.0000000000000057.


Instruction: What can be used to better diagnose and manage HBP in clinical settings for patients with HBP?

Output: development of algorithms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to better diagnose and manage HBP in clinical settings for patients with HBP?. ### Response: development of algorithms.


Instruction: What are some examples of telehealth, m-health, or e-health strategies?

Output: Table B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some examples of telehealth, m-health, or e-health strategies?. ### Response: Table B.


Instruction: What is required for patients engaged in self-monitoring to communicate home BP measurements to the healthcare provider team?

Output: a platform

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required for patients engaged in self-monitoring to communicate home BP measurements to the healthcare provider team?. ### Response: a platform.


Instruction: What may require several methods?

Output: self-monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may require several methods?. ### Response: self-monitoring.


Instruction: How are BP readings delivered via the EHR?

Output: Direct integration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are BP readings delivered via the EHR?. ### Response: Direct integration.


Instruction: How many individuals are designated to implement changes in nonpharmacological treatment based on self-monitoring or behavioral/coaching strategies?

Output: ≥1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many individuals are designated to implement changes in nonpharmacological treatment based on self-monitoring or behavioral/coaching strategies?. ### Response: ≥1.


Instruction: What are some examples of new telehealth technologies?

Output: novel BP measurement devices, data integration software

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some examples of new telehealth technologies?. ### Response: novel BP measurement devices, data integration software.


Instruction: What is a framework to iteratively and routinely assess?

Output: ongoing efficacy of different telehealth strategies for the CDU

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a framework to iteratively and routinely assess?. ### Response: ongoing efficacy of different telehealth strategies for the CDU.


Instruction: What did meta-analyses of RCTs of different telehealth interventions show?

Output: greater SBP and DBP reductions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did meta-analyses of RCTs of different telehealth interventions show?. ### Response: greater SBP and DBP reductions.


Instruction: What did a larger proportion of patients achieve than those achieved with usual care?

Output: BP control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a larger proportion of patients achieve than those achieved with usual care?. ### Response: BP control.


Instruction: The effect of various interventions on BP lowering was significantly greater than what?

Output: BP self-monitoring without transmission of BP data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The effect of various interventions on BP lowering was significantly greater than what?. ### Response: BP self-monitoring without transmission of BP data.


Instruction: What was significantly greater than BP self-monitoring without transmission of BP data?

Output: BP lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was significantly greater than BP self-monitoring without transmission of BP data?. ### Response: BP lowering.


Instruction: What suggests a possible added value of the teletransmission approach?

Output: The effect of various telehealth interventions on BP lowering was significantly greater than that of BP self-monitoring without transmission of BP data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What suggests a possible added value of the teletransmission approach?. ### Response: The effect of various telehealth interventions on BP lowering was significantly greater than that of BP self-monitoring without transmission of BP data.


Instruction: What is the most effective combination of telehealth intervention features?

Output: ≥1 telehealth, m-health, or e-health strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most effective combination of telehealth intervention features?. ### Response: ≥1 telehealth, m-health, or e-health strategies.


Instruction: What has not been demonstrated to be effective as a standalone strategy for improving hypertension control?

Output: telehealth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been demonstrated to be effective as a standalone strategy for improving hypertension control?. ### Response: telehealth.


Instruction: What is digital health?

Output: E- health, or digital health, is the use of emerging communication and information technologies to improve health and health care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is digital health?. ### Response: E- health, or digital health, is the use of emerging communication and information technologies to improve health and health care.


Instruction: What is a subsegment of e-health?

Output: M-health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a subsegment of e-health?. ### Response: M-health.


Instruction: What are some examples of mobile computing and communication technologies?

Output: mobile phones, wearable sensors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some examples of mobile computing and communication technologies?. ### Response: mobile phones, wearable sensors.


Instruction: How many patients were enrolled in the EPHESUS trial112?

Output: >6600

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the EPHESUS trial112?. ### Response: >6600.


Instruction: What was the LV ejection fraction 40%?

Output: ≤40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the LV ejection fraction 40%?. ### Response: ≤40%.


Instruction: How many days after MI were patients randomly assigned to eplerenone or pla-cebo?

Output: 3 to 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days after MI were patients randomly assigned to eplerenone or pla-cebo?. ### Response: 3 to 14.


Instruction: How many days after MI did Eplerenone reduce total mortality?

Output: 3 to 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days after MI did Eplerenone reduce total mortality?. ### Response: 3 to 14.


Instruction: What was the reduction in sudden cardiac death?

Output: 21%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in sudden cardiac death?. ### Response: 21%..


Instruction: How many people were receiving ACE inhibitors and 75% receiving -blockers?

Output: 87%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were receiving ACE inhibitors and 75% receiving -blockers?. ### Response: 87%.


Instruction: What does aldosterone antagonist therapy pro-vides to these agents?

Output: incremental benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does aldosterone antagonist therapy pro-vides to these agents?. ### Response: incremental benefit.


Instruction: Spirono-lactone has not been studied specifically in which ACS?

Output: ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Spirono-lactone has not been studied specifically in which ACS?. ### Response: ACS.


Instruction: What did the RALES trial show for patients with HF?

Output: mortality benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the RALES trial show for patients with HF?. ### Response: mortality benefit.


Instruction: What should be avoided in patients with significantly elevated serum creatinine levels?

Output: Aldosterone antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be avoided in patients with significantly elevated serum creatinine levels?. ### Response: Aldosterone antagonists.


Instruction: What is a serious risk of using aldosterone antagonists?

Output: hyperkalemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a serious risk of using aldosterone antagonists?. ### Response: hyperkalemia.


Instruction: What is a serious risk of hyperkalemia with the use of aldosterone antagonists?

Output: patients with an estimated cre-atinine clearance of <50 mL/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a serious risk of hyperkalemia with the use of aldosterone antagonists?. ### Response: patients with an estimated cre-atinine clearance of <50 mL/min.


Instruction: What is the estimated cre-atinine clearance of 50 mL/min?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the estimated cre-atinine clearance of 50 mL/min?. ### Response: <.


Instruction: Why is close clinical and labo-ratory follow-up needed for patients receiving long-term treatment?

Output: to mitigate the occur -rence and complications of hyperkalemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is close clinical and labo-ratory follow-up needed for patients receiving long-term treatment?. ### Response: to mitigate the occur -rence and complications of hyperkalemia.


Instruction: Aldosterone antagonists are used to mitigate the occur -ence and complications of what?

Output: hyperkalemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aldosterone antagonists are used to mitigate the occur -ence and complications of what?. ### Response: hyperkalemia.


Instruction: What is underused among evi-dence-based medications after MI?

Output: Mineralocorticoid antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is underused among evi-dence-based medications after MI?. ### Response: Mineralocorticoid antagonists.


Instruction: What type of diuretics play a major role in the long-term control of BP?

Output: thiazide and thiazide-type diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diuretics play a major role in the long-term control of BP?. ### Response: thiazide and thiazide-type diuretics.


Instruction: What is used primarily for patients with evidence of increased filling pressures, pulmonary venous congestion or HF?

Output: diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used primarily for patients with evidence of increased filling pressures, pulmonary venous congestion or HF?. ### Response: diuretics.


Instruction: What may precipitate arrhythmias after ACS?

Output: hypokalemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may precipitate arrhythmias after ACS?. ### Response: hypokalemia.


Instruction: What is preferred over thiazide-type diuretics for patients with HF?

Output: Loop diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preferred over thiazide-type diuretics for patients with HF?. ### Response: Loop diuretics.


Instruction: What is the estimated glo-merular filtration rate of patients with CKD?

Output: <45 mL/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the estimated glo-merular filtration rate of patients with CKD?. ### Response: <45 mL/min.


Instruction: What does ACS therapy include several strategies that involve platelet inactivation and anticoagulation to reduce the risk of?

Output: thrombosis and poor clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACS therapy include several strategies that involve platelet inactivation and anticoagulation to reduce the risk of?. ### Response: thrombosis and poor clinical outcomes.


Instruction: Anticoagulant and antiplatelet therapy do not differ in patients with STEMI, NSTEMI, or UA?

Output: relative efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anticoagulant and antiplatelet therapy do not differ in patients with STEMI, NSTEMI, or UA?. ### Response: relative efficacy and safety.


Instruction: In the ACS popula-tion, when are these drugs most effective when given early, they are most effective what?

Output: early. These ther -apies can lead to major bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the ACS popula-tion, when are these drugs most effective when given early, they are most effective what?. ### Response: early. These ther -apies can lead to major bleeding complications.


Instruction: What can lead to major bleeding complications, most commonly in the gastrointestinal tract?

Output: ther -apies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can lead to major bleeding complications, most commonly in the gastrointestinal tract?. ### Response: ther -apies.


Instruction: Where are bleeding complications most common?

Output: gastrointestinal tract and at the site of femoral access for percutaneous coronary interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are bleeding complications most common?. ### Response: gastrointestinal tract and at the site of femoral access for percutaneous coronary interventions.


Instruction: What is most concerning about bleeding complications?

Output: ther -apies can lead to major bleeding complications, most commonly in the gastrointestinal tract and at the site of femoral access for percutaneous coronary interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is most concerning about bleeding complications?. ### Response: ther -apies can lead to major bleeding complications, most commonly in the gastrointestinal tract and at the site of femoral access for percutaneous coronary interventions.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary?. ### Response: Arnett et al.


Instruction: What is the name of the document that summarizes recommendations for nutrition and diet?

Output: Online Data Supplements 4 and 5.COR LOE RecommendationsI B-R1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that summarizes recommendations for nutrition and diet?. ### Response: Online Data Supplements 4 and 5.COR LOE RecommendationsI B-R1.