Instruction: What was the overall quality of the evidence comparing ACEi or ARB with placebo or standard of care inpatients with CKD and severely increased albuminuria withoutdiabetes?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall quality of the evidence comparing ACEi or ARB with placebo or standard of care inpatients with CKD and severely increased albuminuria withoutdiabetes?. ### Response: moderate.


Instruction: Why was the quality of evidence downgraded?

Output: study limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the quality of evidence downgraded?. ### Response: study limitations.


Instruction: Why was the quality of the evidence downgraded?

Output: study limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the quality of the evidence downgraded?. ### Response: study limitations.


Instruction: What were some of the limitations of the study?

Output: small numbers ofevents, inadequate reporting of sequence generation, and allo-cation concealment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were some of the limitations of the study?. ### Response: small numbers ofevents, inadequate reporting of sequence generation, and allo-cation concealment.


Instruction: What was the quality of the evidence for ESKD, doubling of serum creatinine, and CV events?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence for ESKD, doubling of serum creatinine, and CV events?. ### Response: moderate.


Instruction: What was lower than the evidencefor RASi in the population of CKD patients without diabetes?

Output: severely increased albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was lower than the evidencefor RASi in the population of CKD patients without diabetes?. ### Response: severely increased albuminuria.


Instruction: What was lower than the evidence for RASi?

Output: ra-pies in the population of CKD patients without diabetes andseverely increased albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was lower than the evidence for RASi?. ### Response: ra-pies in the population of CKD patients without diabetes andseverely increased albuminuria.


Instruction: What has only been examined in a limited number ofRCTs for MRA of rather short duration and powered forsurrogate outcomes?

Output: RASi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has only been examined in a limited number ofRCTs for MRA of rather short duration and powered forsurrogate outcomes?. ### Response: RASi.


Instruction: The presence of severely increasedalbuminuria and CKD is associated with a higher prevalence of what?

Output: CV disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The presence of severely increasedalbuminuria and CKD is associated with a higher prevalence of what?. ### Response: CV disease.


Instruction: What is CKD associated with a higher prevalence of?

Output: CV disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD associated with a higher prevalence of?. ### Response: CV disease.


Instruction: What is associated with an attendant loss of qualityof life?

Output: severely increasedalbuminuria and CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with an attendant loss of qualityof life?. ### Response: severely increasedalbuminuria and CKD.


Instruction: In the opinion of the Work Group, most patients would place emphasis on preventing what?

Output: CV outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the opinion of the Work Group, most patients would place emphasis on preventing what?. ### Response: CV outcomes.


Instruction: What should be considered when treating patients with CKD?

Output: The risks, bene ﬁts, resource use, andcosts of RASi therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered when treating patients with CKD?. ### Response: The risks, bene ﬁts, resource use, andcosts of RASi therapy.


Instruction: What are the costs of generic RASi medication?

Output: generallylow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the costs of generic RASi medication?. ### Response: generallylow.


Instruction: How many patients underwent an analysis of creases in volume and significant decreases in mechanical valve use?

Output: 41,227

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent an analysis of creases in volume and significant decreases in mechanical valve use?. ### Response: 41,227.


Instruction: Who conducted the analysis of 41,227 patients over 5 years from the Society for Cardiotho-racic Surgery in Great Britain and Ireland National database?

Output: Society of Thoracic Surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who conducted the analysis of 41,227 patients over 5 years from the Society for Cardiotho-racic Surgery in Great Britain and Ireland National database?. ### Response: Society of Thoracic Surgeons.


Instruction: What is the age range for aortic valve replacement?

Output: 55 to 70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age range for aortic valve replacement?. ### Response: 55 to 70 years.


Instruction: What was the age of the patients enrolled in the prospective randomized evaluation of mechanical versus biological valves?

Output: 55 to 70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the age of the patients enrolled in the prospective randomized evaluation of mechanical versus biological valves?. ### Response: 55 to 70 years.


Instruction: When was the J Am Coll Cardiol.54:1862-8?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol.54:1862-8?. ### Response: 2009.


Instruction: How long did the Carpentier-Edwards aortic pericardial bioprosthesis last?

Output: 17 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Carpentier-Edwards aortic pericardial bioprosthesis last?. ### Response: 17 years.


Instruction: What is the Society of Thoracic Surgeons Adult Cardiac Surgery National Database?

Output: Long-term safety and effective-ness of mechanical versus biologic aortic valve prostheses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Society of Thoracic Surgeons Adult Cardiac Surgery National Database?. ### Response: Long-term safety and effective-ness of mechanical versus biologic aortic valve prostheses.


Instruction: How many years of the Carpentier-Edwards aortic pericardial bioprosthesis have been used?

Output: 17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of the Carpentier-Edwards aortic pericardial bioprosthesis have been used?. ### Response: 17.


Instruction: What is the name of the bioprothesis used to replace the Aortic valve?

Output: Carpentier-Edwards Perimount pericardial bioprosthesis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the bioprothesis used to replace the Aortic valve?. ### Response: Carpentier-Edwards Perimount pericardial bioprosthesis.


Instruction: How many patients have had the Biocor porcine bioprosthesis for 20 years?

Output: 1712

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients have had the Biocor porcine bioprosthesis for 20 years?. ### Response: 1712.


Instruction: How many years of experience have patients had with Biocor?

Output: 1712

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of experience have patients had with Biocor?. ### Response: 1712.


Instruction: What was the result of the Han-cock II?

Output: Twenty-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of the Han-cock II?. ### Response: Twenty-year.


Instruction: When was the J Thorac Cardiovasc Surg published?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg published?. ### Response: 2002.


Instruction: What is the name of the JACC state-of-the-art review of the Ross procedure in adults for car -diologists and cardiac surgeons?

Output: Adult Cardiac Surgery National Database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the JACC state-of-the-art review of the Ross procedure in adults for car -diologists and cardiac surgeons?. ### Response: Adult Cardiac Surgery National Database.


Instruction: What type of therapy does Cannegieter SC, Rosendaal FR, Brit E use?

Output: Antithrombotic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy does Cannegieter SC, Rosendaal FR, Brit E use?. ### Response: Antithrombotic.


Instruction: What are the complications of mechanical heart valve prostheses?

Output: Late hemodynamic and clinical out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the complications of mechanical heart valve prostheses?. ### Response: Late hemodynamic and clinical out-comes.


Instruction: What is the cause of bleeding complications?

Output: Thromboembolic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of bleeding complications?. ### Response: Thromboembolic.


Instruction: How is antithrombotic management of patients treated?

Output: LOWERing the INtensity of oral anticoaGulant Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is antithrombotic management of patients treated?. ### Response: LOWERing the INtensity of oral anticoaGulant Therapy.


Instruction: Who is the author of the study?

Output: Zhao Y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study?. ### Response: Zhao Y.


Instruction: What is the name of the study that compares dabig-atran etexilate with warfarin in mechanical heart valve patients?

Output: the Randomized, phase II study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares dabig-atran etexilate with warfarin in mechanical heart valve patients?. ### Response: the Randomized, phase II study.


Instruction: What type of valves are used in prosthetic heart valves?

Output: biologic aortic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valves are used in prosthetic heart valves?. ### Response: biologic aortic.


Instruction: When did the Lancet 374:565-76 publish?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet 374:565-76 publish?. ### Response: 2009.


Instruction: What is the name of the Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt?

Output: RE-ALIGN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt?. ### Response: RE-ALIGN.


Instruction: What is RE-ALIGN?

Output: Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is RE-ALIGN?. ### Response: Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt.


Instruction: When was the Am Heart J.163:931–7.e1 published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am Heart J.163:931–7.e1 published?. ### Response: 2012.


Instruction: What is warfarin used for in patients with mechanical heart valves?

Output: Dabigatran

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is warfarin used for in patients with mechanical heart valves?. ### Response: Dabigatran.


Instruction: What is the N Engl J Med 2013:369:1206–14?

Output: sus warfarin in patients with mechanical heart valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med 2013:369:1206–14?. ### Response: sus warfarin in patients with mechanical heart valves.


Instruction: In what year was the “LOWERING-IT” trial conducted?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the “LOWERING-IT” trial conducted?. ### Response: 2010.


Instruction: What did the “LOWERING-IT” Trial do?

Output: LOWERing the INtensity of oral anticoaGulant Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the “LOWERING-IT” Trial do?. ### Response: LOWERing the INtensity of oral anticoaGulant Therapy.


Instruction: What was the name of the trial?

Output: LOWERING-IT” Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the trial?. ### Response: LOWERING-IT” Trial.


Instruction: When was the Am Heart J.160:171–8?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am Heart J.160:171–8?. ### Response: 2010.


Instruction: What is the name of the book that discusses the diagnosis of heart failure?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that discusses the diagnosis of heart failure?. ### Response: Chronic Heart Failure.


Instruction: What is a scientific statement from the American Heart Association?

Output: Vascular graft infections, mycotic aneu-rysms, and endovascular infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scientific statement from the American Heart Association?. ### Response: Vascular graft infections, mycotic aneu-rysms, and endovascular infections.


Instruction: How many Circulation?

Output: 1486

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Circulation?. ### Response: 1486.


Instruction: What is the name of the scientific statement?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the scientific statement?. ### Response: American Heart Association.


Instruction: What is the name of the organization that publishes Circulation?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that publishes Circulation?. ### Response: American Heart Association.


Instruction: What does Tice AD say about the safety of outpatient parenteral antimicrobial therapy for endo-carditis?

Output: Safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Tice AD say about the safety of outpatient parenteral antimicrobial therapy for endo-carditis?. ### Response: Safety.


Instruction: How many pages are in the Curr Infect Dis Rep 2001?

Output: 3:319–327

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages are in the Curr Infect Dis Rep 2001?. ### Response: 3:319–327.


Instruction: What is the name of the organization that provides practice guidelines for outpatient parenteral antimicrobial therapy?

Output: IDSA guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that provides practice guidelines for outpatient parenteral antimicrobial therapy?. ### Response: IDSA guidelines.


Instruction: When did Clin Infect Dis. 2004:38:1651–1672?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Clin Infect Dis. 2004:38:1651–1672?. ### Response: 2004.


Instruction: What was the title of the study that was published in 2004?

Output: Clin Infect Dis. 2004;38:1651–1672

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the study that was published in 2004?. ### Response: Clin Infect Dis. 2004;38:1651–1672.


Instruction: What is a risk fac-tor for infective endocarditis-related complications?

Output: Poor oral hygiene

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk fac-tor for infective endocarditis-related complications?. ### Response: Poor oral hygiene.


Instruction: What is a risk fac-tor for infective endocarditis-related bacteremia?

Output: Poor oral hygiene

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk fac-tor for infective endocarditis-related bacteremia?. ### Response: Poor oral hygiene.


Instruction: What year did J Am Dent Assoc. 2009:140:1238–1244.

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Am Dent Assoc. 2009:140:1238–1244.. ### Response: 2009.


Instruction: What is the name of the journal that circulated in 2012:126:11–12.

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that circulated in 2012:126:11–12.. ### Response: Circulation.


Instruction: What is a therapeutic end point for the treatment of atrioventricular node reentrant tachycardia by catheter-guided radiofrequency current?

Output: slow pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a therapeutic end point for the treatment of atrioventricular node reentrant tachycardia by catheter-guided radiofrequency current?. ### Response: slow pathway.


Instruction: When did J Am Coll Cardiol. 1993;22:733–40?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 1993;22:733–40?. ### Response: 1993.


Instruction: What is the cause of supra-ventricular tachycardia?

Output: atrioventricular nodal reentry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of supra-ventricular tachycardia?. ### Response: atrioventricular nodal reentry.


Instruction: What is ablation of slow-pathway conduction used for?

Output: selective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ablation of slow-pathway conduction used for?. ### Response: selective.


Instruction: When did N Engl J Med issue 327:313–8?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 327:313–8?. ### Response: 1992.


Instruction: What are electrophysiologic characteristics and results of radiofrequency ablation?

Output: clinical features

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are electrophysiologic characteristics and results of radiofrequency ablation?. ### Response: clinical features.


Instruction: What are age at onset and gen-der of patients with different types of supraventricular tachycardias?

Output: Am J Cardiol. 1992;70:1213–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are age at onset and gen-der of patients with different types of supraventricular tachycardias?. ### Response: Am J Cardiol. 1992;70:1213–.


Instruction: What is a simple technique for selective radio-frequency ablation of the slow pathway in atrioventricular node reentrant tachycardia?

Output: catheter-guided radiofrequency current. J Am Coll Cardiol. 1993;22:733–40. 36. Jackman WM, Beckman KJ, McClelland JH, et al. Treatment of supra-ventricular tachycardia due to atrioventricular nodal reentry, by radio-frequency catheter ablation of slow-pathway conduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simple technique for selective radio-frequency ablation of the slow pathway in atrioventricular node reentrant tachycardia?. ### Response: catheter-guided radiofrequency current. J Am Coll Cardiol. 1993;22:733–40. 36. Jackman WM, Beckman KJ, McClelland JH, et al. Treatment of supra-ventricular tachycardia due to atrioventricular nodal reentry, by radio-frequency catheter ablation of slow-pathway conduction.


Instruction: What was the J Am Coll Cardiol. 1993;21:1612–21?

Output: A simple technique for selective radio-frequency ablation of the slow pathway in atrioventricular node reentrant tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol. 1993;21:1612–21?. ### Response: A simple technique for selective radio-frequency ablation of the slow pathway in atrioventricular node reentrant tachycardia.


Instruction: What is a symptomatic paroxysmal atrial fibrillation?

Output: Spontaneous occurrence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a symptomatic paroxysmal atrial fibrillation?. ### Response: Spontaneous occurrence.


Instruction: What is an untreated tachycardia?

Output: Spontaneous occurrence of symptomatic paroxysmal atrial fibrillation and paroxysmal supraventricu-lar tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an untreated tachycardia?. ### Response: Spontaneous occurrence of symptomatic paroxysmal atrial fibrillation and paroxysmal supraventricu-lar tachycardia.


Instruction: When did Wu D, Denes P, Amat-y-Leon F, et al. publish their findings?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Wu D, Denes P, Amat-y-Leon F, et al. publish their findings?. ### Response: April 23, 2023.


Instruction: What does Kidney International do?

Output: perform physical activity regularly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Kidney International do?. ### Response: perform physical activity regularly.


Instruction: What is the name of the organization that helps patients in whomchapter 2?

Output: kidney-international

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that helps patients in whomchapter 2?. ### Response: kidney-international.


Instruction: What can occur in patients taking cline?

Output: seriousneuropsychiatric symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can occur in patients taking cline?. ### Response: seriousneuropsychiatric symptoms.


Instruction: What framework should physicians use to approach smoking cessation?

Output: 6 A’s framework

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What framework should physicians use to approach smoking cessation?. ### Response: 6 A’s framework.


Instruction: What should smokers offer to help them make a quit attempt?

Output: medication and referral for counseling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should smokers offer to help them make a quit attempt?. ### Response: medication and referral for counseling.


Instruction: What must smokers avoid in order to avoid exposure to environmental tobacco smoke?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must smokers avoid in order to avoid exposure to environmental tobacco smoke?. ### Response: ●.


Instruction: How should SIHD patients be treated?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should SIHD patients be treated?. ### Response: uncertain.


Instruction: What is a major cause of disability in developedcountries and often coexists with SIHD?

Output: Depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major cause of disability in developedcountries and often coexists with SIHD?. ### Response: Depression.


Instruction: What is the most common cause of disability in developed countries?

Output: Depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common cause of disability in developed countries?. ### Response: Depression.


Instruction: What percentage of patients with angiographic evidence of CAD have comorbiddepression?

Output: 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with angiographic evidence of CAD have comorbiddepression?. ### Response: 20%.


Instruction: How many observational studies have demonstrated an asso-ciation between depression and cardiovascular events?

Output: Multiple

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many observational studies have demonstrated an asso-ciation between depression and cardiovascular events?. ### Response: Multiple.


Instruction: How many studies examined 21 prospective studies in healthypopulations and 34 studies in patients with existing IHD?

Output: 239,683

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies examined 21 prospective studies in healthypopulations and 34 studies in patients with existing IHD?. ### Response: 239,683.


Instruction: What percentage greaterincidence was found in healthy cohorts?

Output: 81%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage greaterincidence was found in healthy cohorts?. ### Response: 81%.


Instruction: How much greater was the risk of ischemic events among patients with symptoms of depression over an average follow-up period of 10.8 years?

Output: 81%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much greater was the risk of ischemic events among patients with symptoms of depression over an average follow-up period of 10.8 years?. ### Response: 81%.


Instruction: Patients with established IHD had symptoms of what?

Output: depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with established IHD had symptoms of what?. ### Response: depression.


Instruction: How many studies have reportedestimates of increased risk of IHD?

Output: Relatively few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have reportedestimates of increased risk of IHD?. ### Response: Relatively few.


Instruction: How many studies have reportedestimates of risk that have been adjusted for traditional risk factors or severity of CAD?

Output: Relatively few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have reportedestimates of risk that have been adjusted for traditional risk factors or severity of CAD?. ### Response: Relatively few.


Instruction: In aggregate theobservational cohort studies suggest that depression confers asignificant risk for adverse cardiovascular outcomes.

Output: con-founding by other risk factors or by disease severity isdifficult to exclude

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In aggregate theobservational cohort studies suggest that depression confers asignificant risk for adverse cardiovascular outcomes.. ### Response: con-founding by other risk factors or by disease severity isdifficult to exclude.


Instruction: What is difficult to exclude from most studies in patients with CAD?

Output: depression confers asignificant risk for adverse cardiovascular outcomes, con-founding by other risk factors or by disease severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is difficult to exclude from most studies in patients with CAD?. ### Response: depression confers asignificant risk for adverse cardiovascular outcomes, con-founding by other risk factors or by disease severity.


Instruction: What are the putative mechanisms for a contribution of depression to?

Output: atherogenesis and adverse cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the putative mechanisms for a contribution of depression to?. ### Response: atherogenesis and adverse cardiovascular events.


Instruction: What are the two types of adverse cardiovascular events?

Output: behavioral and biological effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two types of adverse cardiovascular events?. ### Response: behavioral and biological effects.


Instruction: Depression is associated with poor compliance with what strategies?

Output: risk factor–modification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Depression is associated with poor compliance with what strategies?. ### Response: risk factor–modification.


Instruction: Patients diagnosed with depression are 2- to 4-fold less likely to adhere to what?

Output: medications and lifestylerecommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients diagnosed with depression are 2- to 4-fold less likely to adhere to what?. ### Response: medications and lifestylerecommendations.


Instruction: What is the name of the book that describes Stable Ischemic Heart Disease: Full Text e401?

Output: Fihn et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes Stable Ischemic Heart Disease: Full Text e401?. ### Response: Fihn et al.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?

Output: March 2020  Page 33 of 134

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?. ### Response: March 2020  Page 33 of 134.


Instruction: What is the Work Group's confidence in the quality of the evidence very low due to?

Output: subjective outcome assessment, incomplete outcome data, selective reporting, lack of blinding, and recruitment bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Work Group's confidence in the quality of the evidence very low due to?. ### Response: subjective outcome assessment, incomplete outcome data, selective reporting, lack of blinding, and recruitment bias.


Instruction: The body of evidence had what type of bias?

Output: recruitment bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The body of evidence had what type of bias?. ### Response: recruitment bias.


Instruction: What were some of the limitations of the body of evidence?

Output: conf ounders in the analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were some of the limitations of the body of evidence?. ### Response: conf ounders in the analysis.


Instruction: The benefits of improved blood pressure and increased participation in care outweigh the potential harms?

Output: the difference in impact between the diabetic and the non- diabetic population is neither statistically nor clinically significant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The benefits of improved blood pressure and increased participation in care outweigh the potential harms?. ### Response: the difference in impact between the diabetic and the non- diabetic population is neither statistically nor clinically significant.


Instruction: What were patient values and preferences?

Output: somewhat vari ed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were patient values and preferences?. ### Response: somewhat vari ed.


Instruction: How many harms were identified?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many harms were identified?. ### Response: none.


Instruction: What did the Work Group decide upon?

Output: a “Weak for” recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group decide upon?. ### Response: a “Weak for” recommendation.


Instruction: The Work Group decided upon what recommendation?

Output: “Weak for”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Work Group decided upon what recommendation?. ### Response: “Weak for”.


Instruction: What is the systolic blood pressure goal for type 2 diabetes?

Output: <130 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic blood pressure goal for type 2 diabetes?. ### Response: <130 mm Hg.


Instruction: What are the general approaches to hypertension management?

Output: Treatment Goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the general approaches to hypertension management?. ### Response: Treatment Goals.


Instruction: What has been shown to decrease the risk of major adverse cardiovascular events (MACE) in patients with HTN?

Output: Pharmacologic treatment of HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to decrease the risk of major adverse cardiovascular events (MACE) in patients with HTN?. ### Response: Pharmacologic treatment of HTN.


Instruction: What is pharmacologic treatment of HTN used for?

Output: decrease the risk of major adverse cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is pharmacologic treatment of HTN used for?. ### Response: decrease the risk of major adverse cardiovascular events.


Instruction: What is the goal for SBP to be less than 130 mm Hg?

Output: reduction in cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal for SBP to be less than 130 mm Hg?. ### Response: reduction in cardiovascular events.


Instruction: What does the SR and meta -analysis provide evidence in support of?

Output: this recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the SR and meta -analysis provide evidence in support of?. ### Response: this recommendation.


Instruction: How many RCTs compared intensive HTN treatment to standard treatment?

Output: 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs compared intensive HTN treatment to standard treatment?. ### Response: 14.


Instruction: What was the effect of a 10 mm Hg reduction on the relative risk of major cardiovascular events estimated as?

Output: a function of different baseline SBPs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of a 10 mm Hg reduction on the relative risk of major cardiovascular events estimated as?. ### Response: a function of different baseline SBPs.


Instruction: What was estimated as a function of different baseline SBPs?

Output: The effect of a 10 mm Hg reduction on the relative risk of major cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was estimated as a function of different baseline SBPs?. ### Response: The effect of a 10 mm Hg reduction on the relative risk of major cardiovascular events.


Instruction: What was associated with a 10 mm Hg lowering in SBP?

Output: improvements in the composite cardiovascular outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a 10 mm Hg lowering in SBP?. ### Response: improvements in the composite cardiovascular outcome.


Instruction: What was associated with 12% relative risk reduction for major adverse cardiovascular events (MACE) per 10 mm Hg reduction in SBP?

Output: pharmacologic treatment of HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with 12% relative risk reduction for major adverse cardiovascular events (MACE) per 10 mm Hg reduction in SBP?. ### Response: pharmacologic treatment of HTN.


Instruction: What did Ettehad and al. (2016) show about pharmacologic treatment of HTN?

Output: 12% relative risk reduction for major adverse cardiovascular events (MACE) per 10 mm Hg reduction in SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Ettehad and al. (2016) show about pharmacologic treatment of HTN?. ### Response: 12% relative risk reduction for major adverse cardiovascular events (MACE) per 10 mm Hg reduction in SBP.


Instruction: What is the difference in impact between diabetic and non- diabetic populations?

Output: neither statistically nor clinically significant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference in impact between diabetic and non- diabetic populations?. ### Response: neither statistically nor clinically significant.


Instruction: What is a 10 mm Hg reduction in SBP?

Output: improvements in the composite cardiovascular outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 10 mm Hg reduction in SBP?. ### Response: improvements in the composite cardiovascular outcome.


Instruction: How much less is the reduction in MACE observed in the diabetic population?

Output: less than that observed in the non- diabetic population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much less is the reduction in MACE observed in the diabetic population?. ### Response: less than that observed in the non- diabetic population.


Instruction: Atrial fibrillation: antithrombotic therapy and prevention of throm-bosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines.

Output: Chest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation: antithrombotic therapy and prevention of throm-bosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines.. ### Response: Chest.


Instruction: Chest. 2012;141:e531S–75S. S7.4-17 What is a novel user-friendly score called?

Output: HAS-BLED

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chest. 2012;141:e531S–75S. S7.4-17 What is a novel user-friendly score called?. ### Response: HAS-BLED.


Instruction: What does HAS-BLED stand for?

Output: user-friendly score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HAS-BLED stand for?. ### Response: user-friendly score.


Instruction: What is the Euro Heart Survey?

Output: A novel user-friendly score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Euro Heart Survey?. ### Response: A novel user-friendly score.


Instruction: What is Digoxin and mortality in patients with atrial fibrillation?

Output: Lopes RD, Rordorf R, De Ferrari GM, et al. Digoxin and mortality in patients with atrial fibrillation. J Am Coll Cardiol. 2018;71:1063–74

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Digoxin and mortality in patients with atrial fibrillation?. ### Response: Lopes RD, Rordorf R, De Ferrari GM, et al. Digoxin and mortality in patients with atrial fibrillation. J Am Coll Cardiol. 2018;71:1063–74.


Instruction: When was the download from http://ahajournals.org?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the download from http://ahajournals.org?. ### Response: April 23, 2023.


Instruction: What is the KDIGO 2021 CLINICAL PRACTICE GUIDELINE FOR THEMANAGEMENT OF?

Output: BLOOD PRESSURE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the KDIGO 2021 CLINICAL PRACTICE GUIDELINE FOR THEMANAGEMENT OF?. ### Response: BLOOD PRESSURE.


Instruction: What is a comprehensive review of median sternotomy?

Output: Eur J Cardiothorac Surg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comprehensive review of median sternotomy?. ### Response: Eur J Cardiothorac Surg.


Instruction: What is the effect of bilateralinternal thoracic artery harvesting on Superficial and deep sternalinfection?

Output: The role of skeletonization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of bilateralinternal thoracic artery harvesting on Superficial and deep sternalinfection?. ### Response: The role of skeletonization.


Instruction: What increases deep sternal wound infection in diabetic patients?

Output: Use of both internal thoracicarteries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases deep sternal wound infection in diabetic patients?. ### Response: Use of both internal thoracicarteries.


Instruction: What does skeletonization of the internal thoracic artery for coronary revascularization do?

Output: the incidenceof sternal wound infection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does skeletonization of the internal thoracic artery for coronary revascularization do?. ### Response: the incidenceof sternal wound infection.


Instruction: What is the effect of coronary revascularization on the incidence of sternal wound infection?

Output: Effect of skeletonization of theinternal thoracic artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of coronary revascularization on the incidence of sternal wound infection?. ### Response: Effect of skeletonization of theinternal thoracic artery.


Instruction: What was the outcome of red blood cell transfusion after cardiac surgery?

Output: Increased mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of red blood cell transfusion after cardiac surgery?. ### Response: Increased mortality.


Instruction: How many patients had cardiac surgery in 2007?

Output: 116:2544–52.960

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had cardiac surgery in 2007?. ### Response: 116:2544–52.960.


Instruction: Who was the author of the study?

Output: Blanchard A, Hurni M, Ruchat P

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of the study?. ### Response: Blanchard A, Hurni M, Ruchat P.


Instruction: What is the association between bacterial infection and red blood cell transfusion after coronary artery bypass surgery?

Output: Increased mortality, post-operative morbidity, and cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between bacterial infection and red blood cell transfusion after coronary artery bypass surgery?. ### Response: Increased mortality, post-operative morbidity, and cost.


Instruction: When was the Ann Thorac Surg. 73:138–42.961?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Thorac Surg. 73:138–42.961?. ### Response: 2002.


Instruction: What increases the risk of postoperative infection after cardiovascular surgery after transfusion?

Output: Transfusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the risk of postoperative infection after cardiovascular surgery after transfusion?. ### Response: Transfusion.


Instruction: What is the name of the study that examined the incidence of deep and Super-ficial sternal infection after open heart surgery?

Output: A ten years retro-spective study from 1981 to 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the incidence of deep and Super-ficial sternal infection after open heart surgery?. ### Response: A ten years retro-spective study from 1981 to 1991.


Instruction: What year was the study conducted?

Output: 1981 to 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the study conducted?. ### Response: 1981 to 1991.


Instruction: How long did open heart surgery last?

Output: ten years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did open heart surgery last?. ### Response: ten years.


Instruction: When was the study done?

Output: 1981 to 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the study done?. ### Response: 1981 to 1991.


Instruction: What was the effect of allogeneic steroids on heart failure?

Output: risk of postoperative infection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of allogeneic steroids on heart failure?. ### Response: risk of postoperative infection.


Instruction: What is a risk factor for postoperative mediastinitis due to methicillin-resistant Staphylococcusaureus?

Output: Transfusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for postoperative mediastinitis due to methicillin-resistant Staphylococcusaureus?. ### Response: Transfusion.


Instruction: What are the effects ofallogeneic leukocytes in blood transfusions during cardiac surgery?

Output: inflammatory mediators and postoperative complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects ofallogeneic leukocytes in blood transfusions during cardiac surgery?. ### Response: inflammatory mediators and postoperative complications.


Instruction: What is Staphylococcusaureus resistant to?

Output: methicillin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Staphylococcusaureus resistant to?. ### Response: methicillin.


Instruction: What is the name of the disease that is resistant to Methicillin?

Output: Staphylococcusaureus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that is resistant to Methicillin?. ### Response: Staphylococcusaureus.


Instruction: When was the last year of the Am J Infect Control?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last year of the Am J Infect Control?. ### Response: 1991.


Instruction: How long did it take to treat Surgical site infections in cardiac surgery?

Output: 11–year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to treat Surgical site infections in cardiac surgery?. ### Response: 11–year.


Instruction: What is a critical appraisal of antimicrobial prophylaxis in coronary bypasssurgery?

Output: Ariano RE, Zhanel GG. Antimicrobial prophylaxis in coronary bypasssurgery: a critical appraisal. DICP. 1991;25:478–84.971. Matros E, Aranki SF, Bayer LR, et al. Reduction in incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a critical appraisal of antimicrobial prophylaxis in coronary bypasssurgery?. ### Response: Ariano RE, Zhanel GG. Antimicrobial prophylaxis in coronary bypasssurgery: a critical appraisal. DICP. 1991;25:478–84.971. Matros E, Aranki SF, Bayer LR, et al. Reduction in incidence.


Instruction: What is an 11-year perspective?

Output: Surgical site infections incardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an 11-year perspective?. ### Response: Surgical site infections incardiac surgery.


Instruction: When did the Am J Infect Control issue 32:63–8.969?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Am J Infect Control issue 32:63–8.969?. ### Response: 2004.


Instruction: What is bypasssurgery: a critical appraisal?

Output: Antimicrobial prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is bypasssurgery: a critical appraisal?. ### Response: Antimicrobial prophylaxis.


Instruction: DICP. 1991;25:478–84.971.

Output: deep

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: DICP. 1991;25:478–84.971.. ### Response: deep.


Instruction: What is the reduction in incidence of deep tissue surgery?

Output: Reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reduction in incidence of deep tissue surgery?. ### Response: Reduction.


Instruction: Who is the Chair of the ACC/AHA Task Force on Clinical Practice Guidelines?

Output: Methodology and Evidence Review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of the ACC/AHA Task Force on Clinical Practice Guidelines?. ### Response: Methodology and Evidence Review.


Instruction: When possible, what are the recommendations listed in the present guideline based on?

Output: evidence based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When possible, what are the recommendations listed in the present guideline based on?. ### Response: evidence based.


Instruction: What was included in the initial ex-tensive evidence review?

Output: literature de-rived from research involving human subjects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was included in the initial ex-tensive evidence review?. ### Response: literature de-rived from research involving human subjects.


Instruction: Where was literature de-rived from research involving human subjects published?

Output: English

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was literature de-rived from research involving human subjects published?. ### Response: English.


Instruction: What is MEDLINE indexed in?

Output: PubMed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MEDLINE indexed in?. ### Response: PubMed.


Instruction: What is EMBASE?

Output: An initial ex-tensive evidence review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EMBASE?. ### Response: An initial ex-tensive evidence review.


Instruction: When was the search conducted?

Output: May 1980 to July 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the search conducted?. ### Response: May 1980 to July 2017.


Instruction: What is a risk-enhancing factor for ASCVD?

Output: statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk-enhancing factor for ASCVD?. ### Response: statin therapy.


Instruction: What is an inhibitor for PCSK9?

Output: bile acid seques-trants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an inhibitor for PCSK9?. ### Response: bile acid seques-trants.


Instruction: What is included in the Online Data Supplement?

Output: The final evidence tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in the Online Data Supplement?. ### Response: The final evidence tables.


Instruction: What was considered by the writing committee during the guideline writing process?

Output: Additional relevant studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered by the writing committee during the guideline writing process?. ### Response: Additional relevant studies.


Instruction: What does the Online Data Supplement summarize the evidence used by the writing committee to formulate recommendations?

Output: The final evidence tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Online Data Supplement summarize the evidence used by the writing committee to formulate recommendations?. ### Response: The final evidence tables.


Instruction: References selected and published in the present docu-ment are representative and not all-inclusive?

Output: evidence based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: References selected and published in the present docu-ment are representative and not all-inclusive?. ### Response: evidence based.


Instruction: An independent evidence review committee was commissioned to perform what?

Output: a formal systematic review of critical clinical questions related to cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: An independent evidence review committee was commissioned to perform what?. ### Response: a formal systematic review of critical clinical questions related to cholesterol.


Instruction: What was the purpose of the independent evidence review committee?

Output: to perform a formal systematic review of critical clinical questions related to cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the purpose of the independent evidence review committee?. ### Response: to perform a formal systematic review of critical clinical questions related to cholesterol.


Instruction: What is the Table 1 of the ERC?

Output: cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Table 1 of the ERC?. ### Response: cholesterol.


Instruction: What is the magnitude of benefit in terms of individual endpoints and composite ischemic events?

Output: absolute reduction; NNT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the magnitude of benefit in terms of individual endpoints and composite ischemic events?. ### Response: absolute reduction; NNT.


Instruction: In terms of adverse events (eg cancer, rhabdomyolysis, diabetes, NNT), what is the size of harm?

Output: absolute increase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In terms of adverse events (eg cancer, rhabdomyolysis, diabetes, NNT), what is the size of harm?. ### Response: absolute increase.


Instruction: What is the term for acute coronary syndrome?

Output: ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for acute coronary syndrome?. ### Response: ACS.


Instruction: How many participants were involved in large RCTs?

Output: (>1 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants were involved in large RCTs?. ### Response: (>1 000.


Instruction: What was the initial duration of the RCT?

Output: >12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the initial duration of the RCT?. ### Response: >12 months.


Instruction: What is the acronym for atherosclerotic cardiovascular disease?

Output: ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for atherosclerotic cardiovascular disease?. ### Response: ASCVD.


Instruction: What is MI?

Output: myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MI?. ### Response: myocardial infarction.


Instruction: What indicates atherosclerotic cardiovascular disease?

Output: ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates atherosclerotic cardiovascular disease?. ### Response: ASCVD.


Instruction: What does CHD mean?

Output: coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CHD mean?. ### Response: coronary heart disease.


Instruction: What is a risk score for excessive alcohol use?

Output: 0–9 points

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk score for excessive alcohol use?. ### Response: 0–9 points.


Instruction: What is the acronym for American College of Chest Physicians?

Output: ACCP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American College of Chest Physicians?. ### Response: ACCP.


Instruction: OAC stands for what?

Output: oral anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: OAC stands for what?. ### Response: oral anticoagulation.


Instruction: What is TIA?

Output: transient ischemic attack

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TIA?. ### Response: transient ischemic attack.


Instruction: When was this article downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: April 28, 2023.


Instruction: What is the name of the attack that is transient?

Output: TIA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the attack that is transient?. ### Response: TIA.


Instruction: Whose reflections on implantable cardioverter defibrillator treatment with focus on the future and the end-of-life: a qualitative content analysis?

Output: Spouses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Whose reflections on implantable cardioverter defibrillator treatment with focus on the future and the end-of-life: a qualitative content analysis?. ### Response: Spouses.


Instruction: What is a simple clinical risk -model in heart failure based on?

Output: 6 minute walk test performance and NT -proBNP status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simple clinical risk -model in heart failure based on?. ### Response: 6 minute walk test performance and NT -proBNP status.


Instruction: What does NT -proBNP status have to do with specificity for sex and be ta-blockers?

Output: do we need specificity for sex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NT -proBNP status have to do with specificity for sex and be ta-blockers?. ### Response: do we need specificity for sex.


Instruction: What are ta-blockers?

Output: specificity for sex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ta-blockers?. ### Response: specificity for sex.


Instruction: What is the impact of living with heart failure?

Output: everyday life, family support, co -morbidities and access  to healthcare

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of living with heart failure?. ### Response: everyday life, family support, co -morbidities and access  to healthcare.


Instruction: What is a secondary qualitative analysis of support, co-morbidities and access to healthcare?

Output: The implications of living with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a secondary qualitative analysis of support, co-morbidities and access to healthcare?. ### Response: The implications of living with heart failure.


Instruction: What is the name of the 2021 guideline for the secondary prevention of Ischemic Stroke?

Output: 2021 Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2021 guideline for the secondary prevention of Ischemic Stroke?. ### Response: 2021 Guideline.


Instruction: What are cortical and cerebellar lesions and brain-stem or subcortical lesions considered potentially caused by?

Output: large artery atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are cortical and cerebellar lesions and brain-stem or subcortical lesions considered potentially caused by?. ### Response: large artery atherosclerosis.


Instruction: What is considered potentially caused by large artery atherosclerosis?

Output: Cortical and cerebellar lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered potentially caused by large artery atherosclerosis?. ### Response: Cortical and cerebellar lesions.


Instruction: What should exclude potential sources of car-dioembolic embolism?

Output: Diag-nostic studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should exclude potential sources of car-dioembolic embolism?. ### Response: Diag-nostic studies.


Instruction: What are two labora-tory studies to rule out known stroke etiologies?

Output: lipid profile and HbA1c

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two labora-tory studies to rule out known stroke etiologies?. ### Response: lipid profile and HbA1c.


Instruction: A diagnosis of ESUS implies that the stroke is embolic in origin, given the location?

Output: nonlacunar location

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A diagnosis of ESUS implies that the stroke is embolic in origin, given the location?. ### Response: nonlacunar location.


Instruction: What is the source of the embolus?

Output: unknown

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the source of the embolus?. ### Response: unknown.


Instruction: What implies that the cause of the origin is unknown?

Output: cryptogenic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What implies that the cause of the origin is unknown?. ### Response: cryptogenic stroke.


Instruction: Individuals with ESUS have what?

Output: cryptogenic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Individuals with ESUS have what?. ### Response: cryptogenic stroke.


Instruction: What is a key component of patient-centered care?

Output: Shared Decision-MakingShared decision-making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key component of patient-centered care?. ### Response: Shared Decision-MakingShared decision-making.


Instruction: What is shared decision-making?

Output: patient-centered care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shared decision-making?. ### Response: patient-centered care.


Instruction: What does this document provide guidance based on?

Output: a review of the literature

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does this document provide guidance based on?. ### Response: a review of the literature.


Instruction: What is it essential for clinicians to collaboratea-tively develop care plans with?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is it essential for clinicians to collaboratea-tively develop care plans with?. ### Response: patients.


Instruction: What should always be tailored to patients’ individual situations?

Output: ContraindicationsTreatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should always be tailored to patients’ individual situations?. ### Response: ContraindicationsTreatment.


Instruction: What statement did we not include in the recommendations?

Output: “unless contraindicated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What statement did we not include in the recommendations?. ### Response: “unless contraindicated.


Instruction: What are the percentages of ischemic stroke subtypes?

Output: Percentages are approximate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the percentages of ischemic stroke subtypes?. ### Response: Percentages are approximate.


Instruction: What is the TOAST?

Output: Trial of Org 10172 in Acute Stroke Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the TOAST?. ### Response: Trial of Org 10172 in Acute Stroke Treatment.


Instruction: What does TOAST stand for?

Output: Trial of Org 10172 in Acute Stroke Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does TOAST stand for?. ### Response: Trial of Org 10172 in Acute Stroke Treatment.


Instruction: What does ESUS indicate?

Output: embolic stroke of undetermined source

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ESUS indicate?. ### Response: embolic stroke of undetermined source.


Instruction: When was TOAST released?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was TOAST released?. ### Response: April 28, 2023.


Instruction: What is the 2017 VA/SCD Guideline?

Output: Al-Khatib et al 2017 VA/SCD GuidelineSeptember 25, 2018 Circulation. 2018;138:e272–e391. DOI: 10.1161/CIR.0000000000000549 e368CLINICAL STATEMENTS  AND GUIDELINES S7.2.1-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 VA/SCD Guideline?. ### Response: Al-Khatib et al 2017 VA/SCD GuidelineSeptember 25, 2018 Circulation. 2018;138:e272–e391. DOI: 10.1161/CIR.0000000000000549 e368CLINICAL STATEMENTS  AND GUIDELINES S7.2.1-9.


Instruction: What is a high risk of sudden death regardless of origin of syncope?

Output: Syncope in advanced heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a high risk of sudden death regardless of origin of syncope?. ### Response: Syncope in advanced heart failure.


Instruction: What predicts the out-come of cardiomyopathy patients?

Output: Syncope

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts the out-come of cardiomyopathy patients?. ### Response: Syncope.


Instruction: What study did Olshansky B, Poole JE, Johnson G, et al. analyze?

Output: SCD-HeFT study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study did Olshansky B, Poole JE, Johnson G, et al. analyze?. ### Response: SCD-HeFT study.


Instruction: When did J Am Coll Cardiol. 2008:51:1277–82?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2008:51:1277–82?. ### Response: 2008.


Instruction: What is the name of the multicenter automatic defibrillator implantation trial-reduce inap-propriate therapy study?

Output: MADIT-RIT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter automatic defibrillator implantation trial-reduce inap-propriate therapy study?. ### Response: MADIT-RIT.


Instruction: What does MADIT-RIT stand for?

Output: inap-propriate therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MADIT-RIT stand for?. ### Response: inap-propriate therapy.


Instruction: Amiodarone for the prevention of sudden cardiac death: a meta-analysis of randomized controlled trials.

Output: Piccini

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Amiodarone for the prevention of sudden cardiac death: a meta-analysis of randomized controlled trials.. ### Response: Piccini.


Instruction: When did Eur Heart J. 2009:30:1245–53?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 2009:30:1245–53?. ### Response: 2009.


Instruction: What did Claro JC, Candia R, Rada G, et al. compare to other phar -macological interventions?

Output: Amiodarone versus other phar -macological interventions for prevention of sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Claro JC, Candia R, Rada G, et al. compare to other phar -macological interventions?. ### Response: Amiodarone versus other phar -macological interventions for prevention of sudden cardiac death.


Instruction: Cochrane Database Syst Rev. 2015;12:CD008093.

Output: Amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cochrane Database Syst Rev. 2015;12:CD008093.. ### Response: Amiodarone.


Instruction: What predicts subsequent ICD activation in nonisch-emic cardiomyopathy patients?

Output: Ventricular arrhyth-mia inducibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts subsequent ICD activation in nonisch-emic cardiomyopathy patients?. ### Response: Ventricular arrhyth-mia inducibility.


Instruction: When did Pacing Clin Electrophysiol. 2009;32:755-61?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Pacing Clin Electrophysiol. 2009;32:755-61?. ### Response: 2009.


Instruction: What predict ventricular arrhyth-mia inducibility predict?

Output: subsequent ICD activation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predict ventricular arrhyth-mia inducibility predict?. ### Response: subsequent ICD activation.


Instruction: What is the primary prevention of sudden cardiac death in a nonischemic dilated cardiomyopathy population?

Output: reappraisal of the role of programmed ventricular stim-ulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention of sudden cardiac death in a nonischemic dilated cardiomyopathy population?. ### Response: reappraisal of the role of programmed ventricular stim-ulation.


Instruction: What is reappraisal of the role of programmed ventricular stim-ulation?

Output: death in a nonischemic dilated cardiomyopathy population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reappraisal of the role of programmed ventricular stim-ulation?. ### Response: death in a nonischemic dilated cardiomyopathy population.


Instruction: Who is Hilfiker G, Schoenenberger AW, Erne P?

Output: Hilfiker G, Schoenenberger AW

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Hilfiker G, Schoenenberger AW, Erne P?. ### Response: Hilfiker G, Schoenenberger AW.


Instruction: What predicts arrhythmic events?

Output: electro-physiological studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts arrhythmic events?. ### Response: electro-physiological studies.


Instruction: What does Amiodarone use after acute myocardial infarction complicate by heart failure and/or left ventricular dysfunction cause?

Output: excess mortal-ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Amiodarone use after acute myocardial infarction complicate by heart failure and/or left ventricular dysfunction cause?. ### Response: excess mortal-ity.


Instruction: What is Primary Prevention of SCD in Patients With NICM?

Output: S7.2.2-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Primary Prevention of SCD in Patients With NICM?. ### Response: S7.2.2-1.


Instruction: What is the primary prevention of sud-den cardiac death in idiopathic dilated hearts?

Output: Amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention of sud-den cardiac death in idiopathic dilated hearts?. ### Response: Amiodarone.


Instruction: What is the primary prevention of sud-den cardiac death in idiopathic dilated cardiomyopathy called?

Output: the Cardiomyopathy Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention of sud-den cardiac death in idiopathic dilated cardiomyopathy called?. ### Response: the Cardiomyopathy Trial.


Instruction: When was the Cardiomyopathy Trial conducted?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Cardiomyopathy Trial conducted?. ### Response: 2002.


Instruction: What did Bristow MR, Saxon LA, Boehmer J, et al. do?

Output: Cardiac-resynchronization therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Bristow MR, Saxon LA, Boehmer J, et al. do?. ### Response: Cardiac-resynchronization therapy.


Instruction: What year did Engl J Med issue 350:2140-50?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Engl J Med issue 350:2140-50?. ### Response: 2004.


Instruction: What is the name of the paper that describes implantable defibrillators?

Output: Cochrane Database Syst Rev.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the paper that describes implantable defibrillators?. ### Response: Cochrane Database Syst Rev..


Instruction: What is the name of the randomised placebo-controlled trial of simvastatin and ezetimibe in patients with chronic kidney disease?

Output: Study of Heart and Renal Protection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised placebo-controlled trial of simvastatin and ezetimibe in patients with chronic kidney disease?. ### Response: Study of Heart and Renal Protection.


Instruction: When was the trial downloaded from http://ahajournals.org by?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the trial downloaded from http://ahajournals.org by?. ### Response: May 1, 2023.


Instruction: What is the International ST2 Consensus Panel?

Output: sated heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the International ST2 Consensus Panel?. ### Response: sated heart failure.


Instruction: What does Galectin 3 complement in risk stratification?

Output: BNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Galectin 3 complement in risk stratification?. ### Response: BNP.


Instruction: What complements BNP in risk stratification in acute heart failure?

Output: Galectin 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What complements BNP in risk stratification in acute heart failure?. ### Response: Galectin 3.


Instruction: What is the Multinational Observational Cohort on Acute Heart Failure study called?

Output: MOCA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Multinational Observational Cohort on Acute Heart Failure study called?. ### Response: MOCA.


Instruction: What is the MOCA study?

Output: Multinational Observational Cohort on Acute Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MOCA study?. ### Response: Multinational Observational Cohort on Acute Heart Failure.


Instruction: What was the result of the COoperative North Scandinavian Enalapril Survival Study?

Output: Effects of enalapril on mortality in severe congestive heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of the COoperative North Scandinavian Enalapril Survival Study?. ### Response: Effects of enalapril on mortality in severe congestive heart failure.


Instruction: When did the CONSENSUS Trial Study Group publish?

Output: 1987

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the CONSENSUS Trial Study Group publish?. ### Response: 1987.


Instruction: What is the effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure?

Output: 129

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure?. ### Response: 129.


Instruction: What was the N Engl J Med. 1991;325:293–302?

Output: The SOLVD Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med. 1991;325:293–302?. ### Response: The SOLVD Investigators.


Instruction: How did Packer M compare the effects of low and high doses of angiotensin-converting enzyme?

Output: Comparative effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Packer M compare the effects of low and high doses of angiotensin-converting enzyme?. ### Response: Comparative effects.


Instruction: What is the name of the angiotensin-converting enzyme inhibitor?

Output: Galectin 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the angiotensin-converting enzyme inhibitor?. ### Response: Galectin 3.


Instruction: When was this publication released?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication released?. ### Response: May 3, 2023.


Instruction: What is the name of the European Prospective Investigation into Cancer and Nutrition-CVD case-cohort studyESH-CHL-SHOT European Society of Hypertension and Chinese Hypertension League Stroke in Hypertension Optimal Treatment TrialESPRIT European/Australasian Trial in Reversible Ischaemia TrialESPS2 Second European Stroke Prevention StudyESUS embolic stroke of undetermined sourceFASTEST Efficacy and Safety After Acute Ischemia Stroka?

Output: EPIC-CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the European Prospective Investigation into Cancer and Nutrition-CVD case-cohort studyESH-CHL-SHOT European Society of Hypertension and Chinese Hypertension League Stroke in Hypertension Optimal Treatment TrialESPRIT European/Australasian Trial in Reversible Ischaemia TrialESPS2 Second European Stroke Prevention StudyESUS embolic stroke of undetermined sourceFASTEST Efficacy and Safety After Acute Ischemia Stroka?. ### Response: EPIC-CVD.


Instruction: What type of exercise after acute ischaemic stroke?

Output: ExStroke Physical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of exercise after acute ischaemic stroke?. ### Response: ExStroke Physical.


Instruction: What is the name of the electronic support tool that has the most efficacy and safety?

Output: TIA/Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the electronic support tool that has the most efficacy and safety?. ### Response: TIA/Stroke.


Instruction: How is PCSK9 inhibited in Subjects With Elevated Risk?

Output: Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated RiskGELIA German Experience With Low Intensity Anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is PCSK9 inhibited in Subjects With Elevated Risk?. ### Response: Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated RiskGELIA German Experience With Low Intensity Anticoagulation.


Instruction: A1cHR hazard ratioICA internal carotid arteryICARUSS Integrated Care for the Reduce of Secondary StrokeICAS intracranial atherosclerotic stenosisICH intracerebral hemorrhageIE infective endocarditisIMPROVE-IT Improved Reduction of Outcomes: Vytorin Efficacy International TrialINR international normalized ratioINSPiRE-TMS Intensified Secondary Prevention Intending a Reduce Re Recurrent Events in TIA and Minor Strooe PatientsIRIS Insulin

Output: 1HbA1c hemoglobin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A1cHR hazard ratioICA internal carotid arteryICARUSS Integrated Care for the Reduce of Secondary StrokeICAS intracranial atherosclerotic stenosisICH intracerebral hemorrhageIE infective endocarditisIMPROVE-IT Improved Reduction of Outcomes: Vytorin Efficacy International TrialINR international normalized ratioINSPiRE-TMS Intensified Secondary Prevention Intending a Reduce Re Recurrent Events in TIA and Minor Strooe PatientsIRIS Insulin. ### Response: 1HbA1c hemoglobin.


Instruction: What is the name of the Japan EPA Lipid Intervention Study?

Output: Japan Adult MoyamoyaJELIS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Japan EPA Lipid Intervention Study?. ### Response: Japan Adult MoyamoyaJELIS.


Instruction: What is a major adverse cardiovascular event?

Output: MD mean differenceMI myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major adverse cardiovascular event?. ### Response: MD mean differenceMI myocardial infarction.


Instruction: What is a mean differenceMI myocardial infarctionMI magnetic resonance angiographyMRI magnetic resonance imagingNAILED Stroke Nurse Based Age Independent Intervention to Limit Evolution of Disease After StrokenAbbreviation Meaning/PhraseDownloaded from http://ahajournals.org by on April 28, 2023?

Output: major adverse cardiovascular eventMD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a mean differenceMI myocardial infarctionMI magnetic resonance angiographyMRI magnetic resonance imagingNAILED Stroke Nurse Based Age Independent Intervention to Limit Evolution of Disease After StrokenAbbreviation Meaning/PhraseDownloaded from http://ahajournals.org by on April 28, 2023?. ### Response: major adverse cardiovascular eventMD.


Instruction: What percentage of cases had cardiomyopathy misdiagnosed?

Output: 37%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of cases had cardiomyopathy misdiagnosed?. ### Response: 37%.


Instruction: What was reported in 37% of referred cases that were ultimately deter-mined to be structurally normal?

Output: misdiagnosis of cardiomyopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reported in 37% of referred cases that were ultimately deter-mined to be structurally normal?. ### Response: misdiagnosis of cardiomyopathy.


Instruction: Why are the etiologic data for specialized cardiac evaluation not generalizable to the overall population?

Output: skew-ing of age at the time of SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are the etiologic data for specialized cardiac evaluation not generalizable to the overall population?. ### Response: skew-ing of age at the time of SCD.


Instruction: What is skew-ing of age at the time of SCD?

Output: The etiologic data for specialized cardiac evaluation are not general-izable to the overall population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is skew-ing of age at the time of SCD?. ### Response: The etiologic data for specialized cardiac evaluation are not general-izable to the overall population.


Instruction: What was the median age of SCI patients?

Output: 38 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median age of SCI patients?. ### Response: 38 years.


Instruction: When did the peak incidence of S CD occur?

Output: 13-11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the peak incidence of S CD occur?. ### Response: 13-11.


Instruction: How much excess of age did SCD patients have?

Output: 5- to 7-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much excess of age did SCD patients have?. ### Response: 5- to 7-fold.


Instruction: How many times more males/females were in the 31 and 60 year age range?

Output: 5- to 7-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times more males/females were in the 31 and 60 year age range?. ### Response: 5- to 7-fold.


Instruction: What percentage of SCD were due to ischemic heart disease?

Output: 42%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of SCD were due to ischemic heart disease?. ### Response: 42%.


Instruction: How much of the SCD in the overall group was due to viral myocarditis?

Output: 12%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the SCD in the overall group was due to viral myocarditis?. ### Response: 12%.


Instruction: What percentage of 35 year olds were attributed to ischemic heart disease?

Output: 13.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of 35 year olds were attributed to ischemic heart disease?. ### Response: 13.5%.


Instruction: What percentage were unexplained in the subgroup 55 years of age?

Output: 0.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage were unexplained in the subgroup 55 years of age?. ### Response: 0.8%.


Instruction: Why is interrogation of the ICD important?

Output: to confirm proper device functioning

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is interrogation of the ICD important?. ### Response: to confirm proper device functioning.


Instruction: What is important to confirm proper device functioning?

Output: interrogation of the ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to confirm proper device functioning?. ### Response: interrogation of the ICD.


Instruction: What can provide infor-mation on the mechanism of death?

Output: interrogation of the ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can provide infor-mation on the mechanism of death?. ### Response: interrogation of the ICD.