Instruction: How long did the study in France last?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study in France last?. ### Response: 1-year.


Instruction: What type of endocarditis is most common in patients with aortic stenosis?

Output: Bacterial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of endocarditis is most common in patients with aortic stenosis?. ### Response: Bacterial.


Instruction: What is another name for ventricular septal defect?

Output: aortic stenosis, pulmonary stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for ventricular septal defect?. ### Response: aortic stenosis, pulmonary stenosis.


Instruction: In what year was the journal Circulation published?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the journal Circulation published?. ### Response: 1993.


Instruction: What is the name of the disease that affects prosthetic valve endocarditis?

Output: Bacterial endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects prosthetic valve endocarditis?. ### Response: Bacterial endocarditis.


Instruction: What are the names of the authors of Mandell,Douglas, and Bennett’s Principles and Practice of Infectious Diseases?

Output: Mandell GL, Bennett JE, Dolin R

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of Mandell,Douglas, and Bennett’s Principles and Practice of Infectious Diseases?. ### Response: Mandell GL, Bennett JE, Dolin R.


Instruction: Where is Elsevier Churchill Livingstone located?

Output: Philadelphia, Pa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Elsevier Churchill Livingstone located?. ### Response: Philadelphia, Pa.


Instruction: What is the name of the publisher that published Diseases in 2005?

Output: Elsevier Churchill Livingstone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the publisher that published Diseases in 2005?. ### Response: Elsevier Churchill Livingstone.


Instruction: What is the name of the randomized trial that evaluated the efficacy of adding mitral valve restrictive annuloplasty to coronary artery bypass grafting?

Output: POINT: Efficacy of adding mitral valve restrictive annuloplasty to coronary artery bypass grafting in patients with moderate ischemic mitral valve regurgitation: a randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial that evaluated the efficacy of adding mitral valve restrictive annuloplasty to coronary artery bypass grafting?. ### Response: POINT: Efficacy of adding mitral valve restrictive annuloplasty to coronary artery bypass grafting in patients with moderate ischemic mitral valve regurgitation: a randomized trial.


Instruction: How many patients were enrolled in the 2009 trial?

Output: 138:278

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the 2009 trial?. ### Response: 138:278.


Instruction: What is the name of the disease that affects the mitral valve?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects the mitral valve?. ### Response: heart failure.


Instruction: What are the names of the patients with functional mitral regurgitation and severe left ventricular dysfunction?

Output: Samad Z, Shaw LK, Phelan M, et al. Management and outcomes in pa-tients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the patients with functional mitral regurgitation and severe left ventricular dysfunction?. ### Response: Samad Z, Shaw LK, Phelan M, et al. Management and outcomes in pa-tients.


Instruction: When did Eur Heart J. 2015 issue 36:2733-41?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 2015 issue 36:2733-41?. ### Response: 2015.


Instruction: What is the title of the 2016 issue of the Lancet?

Output: 387:1324–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the 2016 issue of the Lancet?. ### Response: 387:1324–.


Instruction: What was the name of the study that examined the effect of mitral regurgitation re-pair on survival in the surgical treatment for ischemic heart failure?

Output: Circulation. 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that examined the effect of mitral regurgitation re-pair on survival in the surgical treatment for ischemic heart failure?. ### Response: Circulation. 2012.


Instruction: When did Circulation issue 125?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation issue 125?. ### Response: 2012.


Instruction: What is the impact of mitral disease etiology on operative mortality after mitral valve operations?

Output: survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of mitral disease etiology on operative mortality after mitral valve operations?. ### Response: survival.


Instruction: What was the Society of Thoracic Surgeons Adult Cardiac Surgery Database analysis of?

Output: Isolated mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Society of Thoracic Surgeons Adult Cardiac Surgery Database analysis of?. ### Response: Isolated mitral valve surgery.


Instruction: What is the name of the study that found mitral regurgitation associated with mitral annular dilation in patients with lone atrial fibrillation?

Output: echocardiographic study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that found mitral regurgitation associated with mitral annular dilation in patients with lone atrial fibrillation?. ### Response: echocardiographic study.


Instruction: What year did Echocardiography report on mitral valve repair?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Echocardiography report on mitral valve repair?. ### Response: 2009.


Instruction: What type of valve repair for severe mitral regurgitation secondary to lone atrial fibrillation?

Output: Mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve repair for severe mitral regurgitation secondary to lone atrial fibrillation?. ### Response: Mitral.


Instruction: What year did Eur J Cardiothorac Surg.42:634–7?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Eur J Cardiothorac Surg.42:634–7?. ### Response: 2012.


Instruction: Takahashi, Abe, Sasaki, et al. repaired the mitral valve in patients with what condition?

Output: chronic atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Takahashi, Abe, Sasaki, et al. repaired the mitral valve in patients with what condition?. ### Response: chronic atrial fibrillation.


Instruction: Interact Car -diovasc Thorac Surg 2015;21:163–8.

Output: 20. Takahashi Y, Abe Y, Sasaki Y, et al. Mitral valve repair for atrial functional mitral regurgitation in patients with chronic atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Interact Car -diovasc Thorac Surg 2015;21:163–8.. ### Response: 20. Takahashi Y, Abe Y, Sasaki Y, et al. Mitral valve repair for atrial functional mitral regurgitation in patients with chronic atrial fibrillation.


Instruction: What is atrial fibrillation?

Output: chronic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atrial fibrillation?. ### Response: chronic.


Instruction: What is the impact of mitral valve annuloplasty on mortality risk?

Output: Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of mitral valve annuloplasty on mortality risk?. ### Response: Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction.


Instruction: How long does sur gical treatment of severe ischemic mitral regurgitation last?

Output: Two-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does sur gical treatment of severe ischemic mitral regurgitation last?. ### Response: Two-year.


Instruction: What is the impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction?

Output: Relation of frequency and sever -ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction?. ### Response: Relation of frequency and sever -ity.


Instruction: What is a long-term outcome and prognostic implications with quantitative Doppler assessment?

Output: Ischemic mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a long-term outcome and prognostic implications with quantitative Doppler assessment?. ### Response: Ischemic mitral regurgitation.


Instruction: What are the prognostic implications of quantitative Doppler assessment?

Output: long-term outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the prognostic implications of quantitative Doppler assessment?. ### Response: long-term outcome.


Instruction: When did Circulation.103:1759-64.

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation.103:1759-64.. ### Response: 2001.


Instruction: What is the long-term outcome of patients with heart failure and dynamic functional mitral regurgitation?

Output: survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term outcome of patients with heart failure and dynamic functional mitral regurgitation?. ### Response: survival.


Instruction: What was the Eur Heart J. 2005:26:1528-32?

Output: Long-term outcome of patients with heart failure and dynamic functional mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Eur Heart J. 2005:26:1528-32?. ### Response: Long-term outcome of patients with heart failure and dynamic functional mitral regurgitation.


Instruction: What is the relationship between frequency and sever-ity of mitral regurgitation to survival in patients with heart failure and left ventricular systolic dysfunction?

Output: Relation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between frequency and sever-ity of mitral regurgitation to survival in patients with heart failure and left ventricular systolic dysfunction?. ### Response: Relation.


Instruction: What is a quantitative prognostic value of func-tional mitral re-gurgitation in heart failure patients?

Output: Doppler assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a quantitative prognostic value of func-tional mitral re-gurgitation in heart failure patients?. ### Response: Doppler assessment.


Instruction: What is func-tional mitral regurgitation in patients with heart failure?

Output: Independent prognostic value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is func-tional mitral regurgitation in patients with heart failure?. ### Response: Independent prognostic value.


Instruction: How many patients had ischaemic and non-ischaemic dilated car?

Output: 1256

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had ischaemic and non-ischaemic dilated car?. ### Response: 1256.


Instruction: What is another name for AV block?

Output: ventricular tachyarrhythmia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for AV block?. ### Response: ventricular tachyarrhythmia.


Instruction: What is an alternative diagnosis for LV hypertrophy?

Output: Differential Diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an alternative diagnosis for LV hypertrophy?. ### Response: Differential Diagnosis.


Instruction: What can cause angina in the absence of signifi-cant anatomic coronary obstruction?

Output: myocardial oxygen supply

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can cause angina in the absence of signifi-cant anatomic coronary obstruction?. ### Response: myocardial oxygen supply.


Instruction: What can other coexisting conditions induce or exacerbate symptoms?

Output: myocardialischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can other coexisting conditions induce or exacerbate symptoms?. ### Response: myocardialischemia.


Instruction: What is less often due to IHD than in men?

Output: Chest pain in women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less often due to IHD than in men?. ### Response: Chest pain in women.


Instruction: What can be related to pain in women in the absence of epicardial CAD?

Output: vascular dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be related to pain in women in the absence of epicardial CAD?. ### Response: vascular dysfunction.


Instruction: Hyper-thermia can cause what?

Output: increased oxygen demand

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyper-thermia can cause what?. ### Response: increased oxygen demand.


Instruction: Hyper-thermia, hyperthyroidism, and cocaine or methamphetamineabuse are examples of what?

Output: increased oxygen demand

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyper-thermia, hyperthyroidism, and cocaine or methamphetamineabuse are examples of what?. ### Response: increased oxygen demand.


Instruction: Sympathomimetic toxicity, due to co-caine intoxication, not only increases myocardial oxygendemand, but also induces what type of vasospasm?

Output: coronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sympathomimetic toxicity, due to co-caine intoxication, not only increases myocardial oxygendemand, but also induces what type of vasospasm?. ### Response: coronary.


Instruction: Long-term cocaine use can cause what kind of development in young patients?

Output: premature development of IHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Long-term cocaine use can cause what kind of development in young patients?. ### Response: premature development of IHD.


Instruction: What can cocaine use cause?

Output: premature development of IHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can cocaine use cause?. ### Response: premature development of IHD.


Instruction: What increases LV wall tension?

Output: Severe uncontrolledhypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases LV wall tension?. ### Response: Severe uncontrolledhypertension.


Instruction: Hypertrophic cardiomyopathy and aortic stenosis can induce even more severe LV hypertrophy and resultantwall tension.

Output: Severe uncontrolledhypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertrophic cardiomyopathy and aortic stenosis can induce even more severe LV hypertrophy and resultantwall tension.. ### Response: Severe uncontrolledhypertension.


Instruction: What are two causes of increased myocardial oxygen demand?

Output: Ventricular or supraventricular tachycardias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two causes of increased myocardial oxygen demand?. ### Response: Ventricular or supraventricular tachycardias.


Instruction: What is the prototype for conditions that limit myocardial oxygen supply?

Output: Anemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prototype for conditions that limit myocardial oxygen supply?. ### Response: Anemia.


Instruction: Cardiac output rises when the hemoglo-bin drops to /H110219 g/dL, and ST-T-wave changes (depression orinversion) can occur at levels of what?

Output: /H110217 g/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cardiac output rises when the hemoglo-bin drops to /H110219 g/dL, and ST-T-wave changes (depression orinversion) can occur at levels of what?. ### Response: /H110217 g/dL.


Instruction: At levels /H110217 g/dL, what can also precipitate angina?

Output: Hypoxemia resulting from pulmonary disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At levels /H110217 g/dL, what can also precipitate angina?. ### Response: Hypoxemia resulting from pulmonary disease.


Instruction: Polycythemia, leukemia,thrombocytosis, and hypergammaglobulinemia are associated with what?

Output: increased blood viscosity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Polycythemia, leukemia,thrombocytosis, and hypergammaglobulinemia are associated with what?. ### Response: increased blood viscosity.


Instruction: What can flow and precipitate angina even in patients without significant coronary stenoses?

Output: coronaryartery blood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can flow and precipitate angina even in patients without significant coronary stenoses?. ### Response: coronaryartery blood.


Instruction: What is often a standard exercisetest?

Output: further testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often a standard exercisetest?. ### Response: further testing.


Instruction: When is further testing usually not warranted?

Output: When the probability of disease is /H110215%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is further testing usually not warranted?. ### Response: When the probability of disease is /H110215%,.


Instruction: What is the probability of disease?

Output: /H110215%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the probability of disease?. ### Response: /H110215%,.


Instruction: What is usually not warranted because the likelihood of a false-positive test is actually higher than a true positive?

Output: further testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is usually not warranted because the likelihood of a false-positive test is actually higher than a true positive?. ### Response: further testing.


Instruction: When did Levine et al. publish a Focused Update on Primary PCI1239?

Output: MARCH 15, 2016:1235 –50 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Levine et al. publish a Focused Update on Primary PCI1239?. ### Response: MARCH 15, 2016:1235 –50 2015.


Instruction: When was the focus of the 2015 ACC/AHA/SCAI focused update?

Output: MARCH 15, 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the focus of the 2015 ACC/AHA/SCAI focused update?. ### Response: MARCH 15, 2016.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 49 of 134 Herrod et al. (2018) reported data favoring separate aerobic, resistance, and isometric exercise interventions over control?

Output: SR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 49 of 134 Herrod et al. (2018) reported data favoring separate aerobic, resistance, and isometric exercise interventions over control?. ### Response: SR.


Instruction: What were MDs in SBP and DBP for resistance exercise v ersu s control?

Output: 5.5 mm Hg and - 2.0 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were MDs in SBP and DBP for resistance exercise v ersu s control?. ### Response: 5.5 mm Hg and - 2.0 mm Hg.


Instruction: How many studies included in the SR looked at isometric exercise versu s control?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies included in the SR looked at isometric exercise versu s control?. ### Response: two.


Instruction: MDs of -9.1 mm Hg were reported?

Output: SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: MDs of -9.1 mm Hg were reported?. ### Response: SBP.


Instruction: What was the weight of the participants in a 2016 RCT comparing aerobic dance training to non-exercise controls?

Output: 5.1 mm Hg and -2.2 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the weight of the participants in a 2016 RCT comparing aerobic dance training to non-exercise controls?. ### Response: 5.1 mm Hg and -2.2 mm Hg.


Instruction: What were the participants on two antihypertensive agents on?

Output: aerobic dance training

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the participants on two antihypertensive agents on?. ### Response: aerobic dance training.


Instruction: What type of training did a larger proportion of dance group participants do?

Output: aerobic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of training did a larger proportion of dance group participants do?. ### Response: aerobic.


Instruction: What was the BMI of control group participants?

Output: higher BMI at baseline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the BMI of control group participants?. ### Response: higher BMI at baseline.


Instruction: Recreational group sports may offer similar blood pressure reductions as what?

Output: combination  aerobic/resistance exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recreational group sports may offer similar blood pressure reductions as what?. ### Response: combination  aerobic/resistance exercise.


Instruction: What may offer similar blood pressure reductions as combination aerobic/resistance exercise?

Output: Recreational group sports

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may offer similar blood pressure reductions as combination aerobic/resistance exercise?. ### Response: Recreational group sports.


Instruction: Bellissimo et al. (2018) conducted an SR and meta-analysis to estimate the pooled effects of what?

Output: community -based, recreational- level group sports

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bellissimo et al. (2018) conducted an SR and meta-analysis to estimate the pooled effects of what?. ### Response: community -based, recreational- level group sports.


Instruction: How long did intervention groups average?

Output: six months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did intervention groups average?. ### Response: six months.


Instruction: How long was the average intervention duration?

Output: six months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the average intervention duration?. ### Response: six months.


Instruction: What was the average duration of the intervention?

Output: six months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the average duration of the intervention?. ### Response: six months.


Instruction: What type of group sports did the intervention favor?

Output: recreational

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of group sports did the intervention favor?. ### Response: recreational.


Instruction: What type of cholesterol and BMI were seen with intervention groups?

Output: low -density lipoprotein ( LDL)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of cholesterol and BMI were seen with intervention groups?. ### Response: low -density lipoprotein ( LDL).


Instruction: What group sports did statistically significant differences favor?

Output: dance training

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group sports did statistically significant differences favor?. ### Response: dance training.


Instruction: Reichert et al. examined the blood pressure effects of aquatic based exercise vs what type of training?

Output: land training

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Reichert et al. examined the blood pressure effects of aquatic based exercise vs what type of training?. ### Response: land training.


Instruction: What type of intervention was limited to exercise performed in an upright position?

Output: Aquatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention was limited to exercise performed in an upright position?. ### Response: Aquatic.


Instruction: What is the difference in blood pressure for aquatic -based exercise?

Output: Improvements in blood pressure for aquatic -based exercise v ersu s control reached statistical significance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference in blood pressure for aquatic -based exercise?. ### Response: Improvements in blood pressure for aquatic -based exercise v ersu s control reached statistical significance.


Instruction: What did the sensitivity analyses of HTN and DBP determine?

Output: statistical significance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the sensitivity analyses of HTN and DBP determine?. ### Response: statistical significance.


Instruction: What did evidence review not suggest?

Output: meaning ful differences between higher and lower intensities of

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did evidence review not suggest?. ### Response: meaning ful differences between higher and lower intensities of.


Instruction: Why did these factors complicate recommendations in previousAHA guidelines on prevention of IE?

Output: overemphasis on antibiotic prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did these factors complicate recommendations in previousAHA guidelines on prevention of IE?. ### Response: overemphasis on antibiotic prophylaxis.


Instruction: What did the collective published data suggest that the vast majority of dental office visits result in?

Output: bacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the collective published data suggest that the vast majority of dental office visits result in?. ### Response: bacteremia.


Instruction: Why is there no evidence-based method to decide which procedures should require prophylaxis?

Output: no data showthat the incidence, magnitude, or duration of bacteremia fromany dental procedure increase the risk of IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there no evidence-based method to decide which procedures should require prophylaxis?. ### Response: no data showthat the incidence, magnitude, or duration of bacteremia fromany dental procedure increase the risk of IE.


Instruction: What is not clear which dental procedures are more or less likely to cause a transient bacteremia or result in a greater risk?

Output: itis not clear which dental procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not clear which dental procedures are more or less likely to cause a transient bacteremia or result in a greater risk?. ### Response: itis not clear which dental procedures.


Instruction: What is not recommended in patients with underlying cardiac conditions to prevent IE that might result from bacteremias associated with routine dailyactivities?

Output: lifelongantibiotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended in patients with underlying cardiac conditions to prevent IE that might result from bacteremias associated with routine dailyactivities?. ### Response: lifelongantibiotic therapy.


Instruction: What could result from bacteremias associated with routine daily activities?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could result from bacteremias associated with routine daily activities?. ### Response: IE.


Instruction: What have the AHA guidelines for prevention of IE resulted in overemphasis on?

Output: antibiotic prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have the AHA guidelines for prevention of IE resulted in overemphasis on?. ### Response: antibiotic prophylaxis.


Instruction: What is more important in reducing the lifetime risk of IE than the administration of antibiotic prophylaxis for a dental procedure?

Output: dental care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more important in reducing the lifetime risk of IE than the administration of antibiotic prophylaxis for a dental procedure?. ### Response: dental care.


Instruction: What is the effect of antibiotic therapy on Bacteremia From a Dental Procedure?

Output: it does not eliminatebacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of antibiotic therapy on Bacteremia From a Dental Procedure?. ### Response: it does not eliminatebacteremia.


Instruction: What is the ability of antibiotic therapy to prevent or reduce the frequency, magnitude, or duration of bacteremia associated with a dental procedure?

Output: controversial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ability of antibiotic therapy to prevent or reduce the frequency, magnitude, or duration of bacteremia associated with a dental procedure?. ### Response: controversial.


Instruction: What did some studies report that antibiotics administered beforea dental proce-dure reduced?

Output: the frequency, nature, and/or duration of bac-teremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some studies report that antibiotics administered beforea dental proce-dure reduced?. ### Response: the frequency, nature, and/or duration of bac-teremia.


Instruction: What does amoxicillin therapy reduce the incidence, nature, and duration of?

Output: bacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does amoxicillin therapy reduce the incidence, nature, and duration of?. ### Response: bacteremia.


Instruction: What does not eliminatebacteremia?

Output: amoxicillin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not eliminatebacteremia?. ### Response: amoxicillin therapy.


Instruction: What does amoxicillin therapy reduce the risk of?

Output: orprevents IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does amoxicillin therapy reduce the risk of?. ### Response: orprevents IE.


Instruction: What did Hall et al78 report was not effective in reducing the frequency of bacteremia compared with untreated control subjects?

Output: penicillin V noramoxicillin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Hall et al78 report was not effective in reducing the frequency of bacteremia compared with untreated control subjects?. ### Response: penicillin V noramoxicillin therapy.


Instruction: Who reported that penicillin orampicillin therapy reduced the percentage of viridans in patients who underwent a dental extraction?

Output: Hall et al78

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reported that penicillin orampicillin therapy reduced the percentage of viridans in patients who underwent a dental extraction?. ### Response: Hall et al78.


Instruction: What did penicillin orampicillin therapy decrease in viridans group streptococci and anaerobes inculture?

Output: percentage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did penicillin orampicillin therapy decrease in viridans group streptococci and anaerobes inculture?. ### Response: percentage.


Instruction: What was not significant difference in the percent-age of patients with positive cultures 10 minutes after toothextraction?

Output: 24

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not significant difference in the percent-age of patients with positive cultures 10 minutes after toothextraction?. ### Response: 24.


Instruction: Who reported thatcefaclor-treated patients did not have a reduction of postprocedure bacteremia?

Output: Hall et al77

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reported thatcefaclor-treated patients did not have a reduction of postprocedure bacteremia?. ### Response: Hall et al77.


Instruction: How many studies showed that erythromycin reduced postprocedure bacteremia in one75 patients?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies showed that erythromycin reduced postprocedure bacteremia in one75 patients?. ### Response: 2.


Instruction: What did patients not have compared with untreated control?

Output: a reduction of postpro-cedure bacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients not have compared with untreated control?. ### Response: a reduction of postpro-cedure bacteremia.


Instruction: What should not be performed because it can reduce the odds of a favorable outcome at 3 months?

Output: High-dose, very early mobilization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be performed because it can reduce the odds of a favorable outcome at 3 months?. ### Response: High-dose, very early mobilization.


Instruction: Harm B-RRecommendation wording changed from 2016 Rehab Guidelines to match what stratifications?

Output: COR III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Harm B-RRecommendation wording changed from 2016 Rehab Guidelines to match what stratifications?. ### Response: COR III.


Instruction: What did the 2016 Rehab Guidelines match?

Output: COR III stratifications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2016 Rehab Guidelines match?. ### Response: COR III stratifications.


Instruction: What was the LOE revised to conform with?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the LOE revised to conform with?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: The AVERT RCT compared high-dose, very early mobilization with what?

Output: standard-of-care mobility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The AVERT RCT compared high-dose, very early mobilization with what?. ### Response: standard-of-care mobility.


Instruction: Mobilization was begun within how many hours of stroke onset?

Output: 24

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Mobilization was begun within how many hours of stroke onset?. ### Response: 24.


Instruction: Normal care typically was 24 hours after the onset of what?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Normal care typically was 24 hours after the onset of what?. ### Response: stroke.


Instruction: At least how many additional out-of-bed sessions were there compared with usual care?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At least how many additional out-of-bed sessions were there compared with usual care?. ### Response: 3.


Instruction: What was the mRS score at 3 months after stroke defined as?

Output: 0 to 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mRS score at 3 months after stroke defined as?. ### Response: 0 to 2.


Instruction: How many patients were randomly assigned?

Output: 2104

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were randomly assigned?. ### Response: 2104.


Instruction: What group had less favorable outcomes after stroke?

Output: high-dose, very early mobilization group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group had less favorable outcomes after stroke?. ### Response: high-dose, very early mobilization group.


Instruction: How many patients died in the high-dose, very early mobilization group?

Output: 8% versus 7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients died in the high-dose, very early mobilization group?. ### Response: 8% versus 7%.


Instruction: What percentage of patients had a nonfatal serious adverse event?

Output: 19% versus 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients had a nonfatal serious adverse event?. ### Response: 19% versus 20%.


Instruction: What is a serious adverse event with high-dose, very early mobilization?

Output: nonfatal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a serious adverse event with high-dose, very early mobilization?. ### Response: nonfatal.


Instruction: In-Hospital Management of AIS: Treatment of Acute Complications5.1. Brain Swelling5.1.1. General Recommendations COR LOE New, Revised or Unchanged1. Patients with large territorial cerebral and cerebellar infarctions are at high risk for developing what?

Output: brain swelling and herniation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In-Hospital Management of AIS: Treatment of Acute Complications5.1. Brain Swelling5.1.1. General Recommendations COR LOE New, Revised or Unchanged1. Patients with large territorial cerebral and cerebellar infarctions are at high risk for developing what?. ### Response: brain swelling and herniation.


Instruction: What are cerebellar infarctions at high risk for?

Output: developing brain swelling and herniation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are cerebellar infarctions at high risk for?. ### Response: developing brain swelling and herniation.


Instruction: What should take place quickly with patients and family or next of kin?

Output: Discussion of care options and possible outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should take place quickly with patients and family or next of kin?. ### Response: Discussion of care options and possible outcomes.


Instruction: What can cause serious and even life-threatening complications in patients with large territorial cerebral and cerebellar infarctions?

Output: Brain swelling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can cause serious and even life-threatening complications in patients with large territorial cerebral and cerebellar infarctions?. ### Response: Brain swelling.


Instruction: What can be managed medically?

Output: less severe swelling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be managed medically?. ### Response: less severe swelling.


Instruction: What is the only effective option for very severe cases?

Output: surgical treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only effective option for very severe cases?. ### Response: surgical treatment.


Instruction: Decompression surgery has been shown to reduce what?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Decompression surgery has been shown to reduce what?. ### Response: mortality.


Instruction: Preexisting decisions about end-of-life and degree of treatment performed in the face of severe neurological injury must be considered?

Output: surgical treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preexisting decisions about end-of-life and degree of treatment performed in the face of severe neurological injury must be considered?. ### Response: surgical treatment.


Instruction: Tables LXIX and LXX in online Data Supplement 1 include what?

Output: family or next of kin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tables LXIX and LXX in online Data Supplement 1 include what?. ### Response: family or next of kin.


Instruction: What distinguishes low flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis?

Output: Differential left ventricular remodel-ling and longitudinal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What distinguishes low flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis?. ### Response: Differential left ventricular remodel-ling and longitudinal function.


Instruction: What does Mehrotra P, Jansen K, Flynn AW, et al. do?

Output: Differential left ventricular remodel-ling and longitudinal function distinguishes low flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Mehrotra P, Jansen K, Flynn AW, et al. do?. ### Response: Differential left ventricular remodel-ling and longitudinal function distinguishes low flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis.


Instruction: Invasive hemodynamic characteris-tics of what?

Output: low gradient severe aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Invasive hemodynamic characteris-tics of what?. ### Response: low gradient severe aortic stenosis.


Instruction: Invasive hemodynamic characteris-tics of low gradient severe aortic stenosis despite preserved ejection frac-tion?

Output: 72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Invasive hemodynamic characteris-tics of low gradient severe aortic stenosis despite preserved ejection frac-tion?. ### Response: 72.


Instruction: What is the name of the journal that studies the hemodynamic characteristics of patients with low-flow severe Aortic Stenosis?

Output: J Am Heart Assoc.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the hemodynamic characteristics of patients with low-flow severe Aortic Stenosis?. ### Response: J Am Heart Assoc..


Instruction: In what year did J Am Coll Cardiol issue 61:1799-808?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did J Am Coll Cardiol issue 61:1799-808?. ### Response: 2013.


Instruction: What is the name of the 2017 ESC/EACTS guidelines for the management of valvular heart disease?

Output: Eur Heart J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2017 ESC/EACTS guidelines for the management of valvular heart disease?. ### Response: Eur Heart J.


Instruction: What year did Ozkan A, Hachamovitch R, Kapadia SR, et al. study the impact of transcatheter aortic valve replacement?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ozkan A, Hachamovitch R, Kapadia SR, et al. study the impact of transcatheter aortic valve replacement?. ### Response: 2013.


Instruction: What did Ozkan A, Hachamovitch R, Kapadia SR, and Dumesnil JG do?

Output: 75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Ozkan A, Hachamovitch R, Kapadia SR, and Dumesnil JG do?. ### Response: 75.


Instruction: What was the effect of lipid lowering with rosuvas-tatin on?

Output: progression of aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of lipid lowering with rosuvas-tatin on?. ### Response: progression of aortic stenosis.


Instruction: What is the name of the trial that measured the effects of rosuvastatin on the progression of aortic stenosis?

Output: Aortic Sten

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that measured the effects of rosuvastatin on the progression of aortic stenosis?. ### Response: Aortic Sten.


Instruction: What is ASTRONOMER?

Output: Aortic Stenosis Pro-gression Observation: Measuring Effects Of Rosuvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ASTRONOMER?. ### Response: Aortic Stenosis Pro-gression Observation: Measuring Effects Of Rosuvastatin.


Instruction: When did Lancellotti P, Lebois F, Simon M, et al. study the prognostic importance of quantita-tive exercise Doppler echocardiography in asymptomatic valvular stent?

Output: 2010;121:306–14. 77

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Lancellotti P, Lebois F, Simon M, et al. study the prognostic importance of quantita-tive exercise Doppler echocardiography in asymptomatic valvular stent?. ### Response: 2010;121:306–14. 77.


Instruction: Exercise testing to stratify risk in aortic stenosis.

Output: 78. Das P , Rimington H, Chambers J. Exercise testing to stratify risk in aortic stenosis. Eur Heart J. 2005;26:1309–13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise testing to stratify risk in aortic stenosis.. ### Response: 78. Das P , Rimington H, Chambers J. Exercise testing to stratify risk in aortic stenosis. Eur Heart J. 2005;26:1309–13.


Instruction: What is the value of exercise testing to evaluate?

Output: the indication for surgery in asymptomatic patients with valvular aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of exercise testing to evaluate?. ### Response: the indication for surgery in asymptomatic patients with valvular aortic stenosis.


Instruction: What is the value of exercise testing to evaluate the indication for surgery in asymptomatic patients with valvular aortic stenosis?

Output: stratify risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of exercise testing to evaluate the indication for surgery in asymptomatic patients with valvular aortic stenosis?. ### Response: stratify risk.


Instruction: What is a comparison of pressure drop/flow slope and haemodynamic measures at rest?

Output: Prediction of symptom-onset in aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison of pressure drop/flow slope and haemodynamic measures at rest?. ### Response: Prediction of symptom-onset in aortic stenosis.


Instruction: What is the difference between drop/flow slope and haemodynamic measures at rest?

Output: Differential left ventricular remodel-ling and longitudinal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between drop/flow slope and haemodynamic measures at rest?. ### Response: Differential left ventricular remodel-ling and longitudinal function.


Instruction: When did Int J Cardiol. 2001:81:131–7?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Int J Cardiol. 2001:81:131–7?. ### Response: 2001.


Instruction: What was the safety of cardiopulmonary exercise testing in a population with high-risk cardiovascular diseases?

Output: The safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the safety of cardiopulmonary exercise testing in a population with high-risk cardiovascular diseases?. ### Response: The safety.


Instruction: How did Dayan V, Vignolo G, Magne J, et al. evaluate the outcome and impact of aortic valve replacement?

Output: Outcome and impact of aortic valve replacement in patients with preserved LVEF and low-gradient aortic ste-nosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Dayan V, Vignolo G, Magne J, et al. evaluate the outcome and impact of aortic valve replacement?. ### Response: Outcome and impact of aortic valve replacement in patients with preserved LVEF and low-gradient aortic ste-nosis.


Instruction: What was the outcome of aortic valve replacement in patients with preserved LVEF and low-gradient ste-nosis?

Output: Outcome and impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of aortic valve replacement in patients with preserved LVEF and low-gradient ste-nosis?. ### Response: Outcome and impact.


Instruction: What did Goldstone AB, Chiu P, Baiocchi M, et al. choose?

Output: Mechanical Versus Bioprosthetic AVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Goldstone AB, Chiu P, Baiocchi M, et al. choose?. ### Response: Mechanical Versus Bioprosthetic AVR.


Instruction: What type of prostheses can be used for aortic valve and mitral valve replacement?

Output: Mechanical or biologic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of prostheses can be used for aortic valve and mitral valve replacement?. ### Response: Mechanical or biologic.


Instruction: What year did N Engl J Med issue 377:1847-57?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med issue 377:1847-57?. ### Response: 2017.


Instruction: Why is noninferiority of closely monitored mechanical valves overshadowed by early mortality benefit in younger patients?

Output: Differential left ventricular remodel-ling and longitudinal function distinguishes low flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis. Eur Heart J. 2013;34:1906–14. 72. Lauten J, Rost C, Breithardt OA, et al. Invasive hemodynamic characteris-tics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is noninferiority of closely monitored mechanical valves overshadowed by early mortality benefit in younger patients?. ### Response: Differential left ventricular remodel-ling and longitudinal function distinguishes low flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis. Eur Heart J. 2013;34:1906–14. 72. Lauten J, Rost C, Breithardt OA, et al. Invasive hemodynamic characteris-tics.


Instruction: What type of valve replacement in patients?

Output: aortic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve replacement in patients?. ### Response: aortic.


Instruction: What year did Ann Thorac Surg publish 93:748–53?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Thorac Surg publish 93:748–53?. ### Response: 2012.


Instruction: S7.2.2-4. Desai AS, Fang JC, Maisel WH, et al. Implantable defibrillators for the prevention of mortality in patients with nonischemic cardiomyopathy: a meta-analysis of what?

Output: randomized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: S7.2.2-4. Desai AS, Fang JC, Maisel WH, et al. Implantable defibrillators for the prevention of mortality in patients with nonischemic cardiomyopathy: a meta-analysis of what?. ### Response: randomized controlled trials.


Instruction: What is the name of the randomized trial in patients with nonischemic dilated cardiomyopathy and asymptomatic non-sustained ventricular tachycardia?

Output: Amiodarone versus implantable cardioverter-defibrillator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial in patients with nonischemic dilated cardiomyopathy and asymptomatic non-sustained ventricular tachycardia?. ### Response: Amiodarone versus implantable cardioverter-defibrillator.


Instruction: What does Amiodarone versus implantable cardioverter-defibrillator do?

Output: randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Amiodarone versus implantable cardioverter-defibrillator do?. ### Response: randomized trial.


Instruction: What year did Am Coll Cardiol publish 41:1707-12?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Am Coll Cardiol publish 41:1707-12?. ### Response: 2003.


Instruction: What is the name of the implantable cardioverter-defibrillator in lamin A/C mutation carriers with cardiac conduction disorders?

Output: Amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the implantable cardioverter-defibrillator in lamin A/C mutation carriers with cardiac conduction disorders?. ### Response: Amiodarone.


Instruction: Who is Pasotti M?

Output: Vaseghi M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Pasotti M?. ### Response: Vaseghi M.


Instruction: What is stratification in dilated cardiolaminopathies?

Output: Long-term outcome and risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stratification in dilated cardiolaminopathies?. ### Response: Long-term outcome and risk.


Instruction: How many carriers of LMNA gene mutations did Meta-analysis of clinical characteristics of 299 carriers of?

Output: 299

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many carriers of LMNA gene mutations did Meta-analysis of clinical characteristics of 299 carriers of?. ### Response: 299.


Instruction: What is the risk of sudden death?

Output: lamin A/C mutations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of sudden death?. ### Response: lamin A/C mutations.


Instruction: What are the risk factors for malignant ventricular arrhythmias in lamin A/C mutation carriers?

Output: Risk factors for malignant ventricular arrhythmias in lamin A/C mutation car -riers: a European cohort study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risk factors for malignant ventricular arrhythmias in lamin A/C mutation carriers?. ### Response: Risk factors for malignant ventricular arrhythmias in lamin A/C mutation car -riers: a European cohort study.


Instruction: What is a meta-analysis of primary prevention implantable cardioverter defibillators in patients with nonischemic cardiomyopathy?

Output: randomized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of primary prevention implantable cardioverter defibillators in patients with nonischemic cardiomyopathy?. ### Response: randomized controlled trials.


Instruction: How many patients were enrolled in the 2017 JAMA Cardiol study?

Output: 685–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the 2017 JAMA Cardiol study?. ### Response: 685–.


Instruction: What type of heart failure is implantation of a defibrillator in?

Output: nonischemic systolic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart failure is implantation of a defibrillator in?. ### Response: nonischemic systolic heart failure.


Instruction: What is a meta-analysis of patients with nonischemic cardiomyopathy?

Output: Primary prevention implantable cardioverter defibillators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of patients with nonischemic cardiomyopathy?. ### Response: Primary prevention implantable cardioverter defibillators.


Instruction: What is an updated meta-analysis of implantable cardioverter-defi-brillator?

Output: Primary prevention implantable cardioverter defibillators in patients with nonischemic cardiomyopathy: a meta-analysis. JAMA Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an updated meta-analysis of implantable cardioverter-defi-brillator?. ### Response: Primary prevention implantable cardioverter defibillators in patients with nonischemic cardiomyopathy: a meta-analysis. JAMA Cardiol.


Instruction: How is the treatment of recurrent VA in patients with NICM?

Output: S7.2.3-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the treatment of recurrent VA in patients with NICM?. ### Response: S7.2.3-1.


Instruction: What is the name of the randomized trial that compared beta-blockers with amiodarone?

Output: OPTIC Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial that compared beta-blockers with amiodarone?. ### Response: OPTIC Study.


Instruction: What is a common side effect of sotalol?

Output: prevention of shocks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common side effect of sotalol?. ### Response: prevention of shocks.


Instruction: When was the OPTIC Study conducted?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the OPTIC Study conducted?. ### Response: 2006.


Instruction: How was the outcome of catheter ablation?

Output: improved survival in patients with structural heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the outcome of catheter ablation?. ### Response: improved survival in patients with structural heart disease.


Instruction: What is the name of the study that evaluated outcomes in catheter abla-tion of ventricular tachycardia in dilated nonischemic cardiomyopathy?

Output: Prospective Heart Centre of Leipzig VT (HELP-VT) Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated outcomes in catheter abla-tion of ventricular tachycardia in dilated nonischemic cardiomyopathy?. ### Response: Prospective Heart Centre of Leipzig VT (HELP-VT) Study.


Instruction: What is a benefit of catheter ablation?

Output: improved survival in patients with structural heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a benefit of catheter ablation?. ### Response: improved survival in patients with structural heart disease.


Instruction: What is ventricular tachycardia associated with after catheter ablation?

Output: improved survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ventricular tachycardia associated with after catheter ablation?. ### Response: improved survival.


Instruction: What is associated with improved survival in patients with structural heart disease?

Output: Freedom from recurrent ventricular tachycardia after catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with improved survival in patients with structural heart disease?. ### Response: Freedom from recurrent ventricular tachycardia after catheter ablation.


Instruction: What was the largest effect of OC use in women with von Willebrand factor levels >90th percentile?

Output: the OR for stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the largest effect of OC use in women with von Willebrand factor levels >90th percentile?. ### Response: the OR for stroke.


Instruction: In nonusers, what was the OR for stroke?

Output: 1.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In nonusers, what was the OR for stroke?. ### Response: 1.6.


Instruction: What did the OR increase to in OC users?

Output: 11.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the OR increase to in OC users?. ### Response: 11.4.


Instruction: What is the risk of stroke in the set-ting of endothelial dysfunction?

Output: increase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of stroke in the set-ting of endothelial dysfunction?. ### Response: increase.


Instruction: What factors should be validated as risk factors?

Output: von Willebrand factor and ADAMTS13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What factors should be validated as risk factors?. ### Response: von Willebrand factor and ADAMTS13.


Instruction: What are von Willebrand factor and ADAMTS13 risk factors for?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are von Willebrand factor and ADAMTS13 risk factors for?. ### Response: stroke.


Instruction: What should women be screened for before hor -monal contraception is prescribed?

Output: thrombophilia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should women be screened for before hor -monal contraception is prescribed?. ### Response: thrombophilia.


Instruction: What should women be screened for before hor -monal contraception is prescribed for them?

Output: thrombophilia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should women be screened for before hor -monal contraception is prescribed for them?. ### Response: thrombophilia.


Instruction: What has been addressed in a large systematic review and meta- analysis of the risk of VTE in the high-risk settings of OC use and pregnancy?

Output: Should women be screened for thrombophilia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been addressed in a large systematic review and meta- analysis of the risk of VTE in the high-risk settings of OC use and pregnancy?. ### Response: Should women be screened for thrombophilia.


Instruction: What are the odds of VTE in women with the factor V Leiden mutation using OCs?

Output: 15-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the odds of VTE in women with the factor V Leiden mutation using OCs?. ### Response: 15-fold.


Instruction: Why is the absolute risk low?

Output: low prevalence of this and other thrombophilias and VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the absolute risk low?. ### Response: low prevalence of this and other thrombophilias and VTE.


Instruction: What is another hereditary thrombophilia?

Output: prothrombin gene mutation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another hereditary thrombophilia?. ### Response: prothrombin gene mutation.


Instruction: What other hereditary thrombophilias are more common than VTE?

Output: prothrombin gene mutation, as well as protein C and antithrombin defi-ciencies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What other hereditary thrombophilias are more common than VTE?. ### Response: prothrombin gene mutation, as well as protein C and antithrombin defi-ciencies.


Instruction: What are the odds of VTE increased in combination with?

Output: OC use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the odds of VTE increased in combination with?. ### Response: OC use.


Instruction: What is more cost-effective than universal screening in women who initiate OCs or desire to become pregnant?

Output: screening based on prior personal or family history of VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more cost-effective than universal screening in women who initiate OCs or desire to become pregnant?. ### Response: screening based on prior personal or family history of VTE.


Instruction: What are much less common than VTE144 so the yield of routine screening would be even lower?

Output: IS and CVT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are much less common than VTE144 so the yield of routine screening would be even lower?. ### Response: IS and CVT.


Instruction: What are women who initiate OCs or desire to become pregnant?

Output: universal screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are women who initiate OCs or desire to become pregnant?. ### Response: universal screening.


Instruction: The cost-effective analysis in this meta-analysis was designed for what?

Output: prevention of VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The cost-effective analysis in this meta-analysis was designed for what?. ### Response: prevention of VTE.


Instruction: What should adaptation to stroke screening in young women include?

Output: obesity, diabetes mellitus, hyperlipidemia, hyperten-sion, and cigarette smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should adaptation to stroke screening in young women include?. ### Response: obesity, diabetes mellitus, hyperlipidemia, hyperten-sion, and cigarette smoking.


Instruction: What is another very important risk factor for stroke in young women?

Output: migraine aura

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another very important risk factor for stroke in young women?. ### Response: migraine aura.


Instruction: What has some evidence sup-porting a further increase in risk for women who also use OCs?

Output: migraine aura

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has some evidence sup-porting a further increase in risk for women who also use OCs?. ### Response: migraine aura.


Instruction: How many women aged 15 to 49 were included in the Stroke Prevention in Young Women study?

Output: 386

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many women aged 15 to 49 were included in the Stroke Prevention in Young Women study?. ### Response: 386.


Instruction: How many women were enrolled in a population-based case-control study?

Output: 386

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many women were enrolled in a population-based case-control study?. ### Response: 386.


Instruction: How many age- and ethnicity- matched control subjects were included in the case-controlled study of 386 women?

Output: 614

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many age- and ethnicity- matched control subjects were included in the case-controlled study of 386 women?. ### Response: 614.


Instruction: What were the odds of stroke for women with probable migraine with visual aura?

Output: 1.5-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the odds of stroke for women with probable migraine with visual aura?. ### Response: 1.5-fold.


Instruction: How much higher were the odds of stroke in migraine type women who smoked cigarettes and used OCs?

Output: 7.0-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher were the odds of stroke in migraine type women who smoked cigarettes and used OCs?. ### Response: 7.0-fold.


Instruction: What was the risk of stroke for migraine type migraine women who did not smoke or use OC?

Output: 7.0-fold higher odds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of stroke for migraine type migraine women who did not smoke or use OC?. ### Response: 7.0-fold higher odds.


Instruction: What did women with probable migraine with visual aura who were OC users but nonsmokers not have a signifi-cantly increased odds of?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did women with probable migraine with visual aura who were OC users but nonsmokers not have a signifi-cantly increased odds of?. ### Response: stroke.


Instruction: What suggests the risk with both OC use and smoking?

Output: migraine aura

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What suggests the risk with both OC use and smoking?. ### Response: migraine aura.


Instruction: What should be minimized in patients with CKD?

Output: the volume of contrastmedia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be minimized in patients with CKD?. ### Response: the volume of contrastmedia.


Instruction: What is not useful for the prevention of contrast-induced AKI?

Output: Administration of N-acetyl-L-cysteine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not useful for the prevention of contrast-induced AKI?. ### Response: Administration of N-acetyl-L-cysteine.


Instruction: What should an allergic reaction to contrast media receive before repeat contrast administration?

Output: appropriate prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should an allergic reaction to contrast media receive before repeat contrast administration?. ### Response: appropriate prophylaxis.


Instruction: What is not beneficial in patients with a prior history of allergic reactions to shellfish or seafood?

Output: anaphylactoid prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not beneficial in patients with a prior history of allergic reactions to shellfish or seafood?. ### Response: anaphylactoid prophylaxis.


Instruction: What is reasonable before PCI to reduce the risk ofperiprocedural MI?

Output: Administration of a high-dose statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable before PCI to reduce the risk ofperiprocedural MI?. ### Response: Administration of a high-dose statin.


Instruction: What should be evaluated for risk of bleeding?

Output: All patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be evaluated for risk of bleeding?. ### Response: All patients.


Instruction: How should glomerular filtration rate be estimated?

Output: In patients undergoing PCI, the glomerular filtration rate should be estimated and thedosage of renally cleared medications should be adjusted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should glomerular filtration rate be estimated?. ### Response: In patients undergoing PCI, the glomerular filtration rate should be estimated and thedosage of renally cleared medications should be adjusted.


Instruction: What should be estimated and thedosage of renally cleared medications be adjusted?

Output: the glomerular filtration rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be estimated and thedosage of renally cleared medications be adjusted?. ### Response: the glomerular filtration rate.


Instruction: What should patients already on daily aspirin therapy take before PCI?

Output: 81 mg to 325 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients already on daily aspirin therapy take before PCI?. ### Response: 81 mg to 325 mg.


Instruction: How many mg before PCI?

Output: 325

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg before PCI?. ### Response: 325.


Instruction: What indicates acute kidney injury?

Output: I B 301,303,304AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates acute kidney injury?. ### Response: I B 301,303,304AKI.


Instruction: COR, class of recommendation.

Output: adjusted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: COR, class of recommendation.. ### Response: adjusted.


Instruction: MI, myocardial infarction.

Output: should be adjusted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: MI, myocardial infarction.. ### Response: should be adjusted.


Instruction: What is epoetin alfa in type 2 diabetes and chronic kidney disease?

Output: Correction of anemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is epoetin alfa in type 2 diabetes and chronic kidney disease?. ### Response: Correction of anemia.


Instruction: What is the name of the drug that is used to correct anemia?

Output: epoetin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to correct anemia?. ### Response: epoetin.


Instruction: What is epoetin alfain chronic kidney disease?

Output: Correction of anemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is epoetin alfain chronic kidney disease?. ### Response: Correction of anemia.


Instruction: What is the N Engl J Med 2006: 355: 2085– 2098.156?

Output: Correction of anemia with epoetin alfain chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med 2006: 355: 2085– 2098.156?. ### Response: Correction of anemia with epoetin alfain chronic kidney disease.


Instruction: What is KDIGO?

Output: Kidney Disease: Improving Global Outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is KDIGO?. ### Response: Kidney Disease: Improving Global Outcomes.


Instruction: What is lowest systolic blood pressure associated with in kidney disease stages 3 to 4?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lowest systolic blood pressure associated with in kidney disease stages 3 to 4?. ### Response: stroke.


Instruction: What is the stage 3 to 4 of chronic kidney disease?

Output: Lowest systolic blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the stage 3 to 4 of chronic kidney disease?. ### Response: Lowest systolic blood pressure.


Instruction: When was the J Am SocNephrol 18:960–966.159?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am SocNephrol 18:960–966.159?. ### Response: 2007.


Instruction: What did Cushman WC, Evans GW, Byington RP et al. have on type 2 diabetes mellitus?

Output: Effects of intensive blood-pressure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Cushman WC, Evans GW, Byington RP et al. have on type 2 diabetes mellitus?. ### Response: Effects of intensive blood-pressure control.


Instruction: What does diuretic-based treatment andcardiovascular events do in patients with mild renal dysfunction enrolled in the systolic hypertension in the elderly program?

Output: lowering of blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does diuretic-based treatment andcardiovascular events do in patients with mild renal dysfunction enrolled in the systolic hypertension in the elderly program?. ### Response: lowering of blood pressure.


Instruction: What year did Arch Intern Med issue 158: 1340–1345.161?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Arch Intern Med issue 158: 1340–1345.161?. ### Response: 1998.


Instruction: What is KidneyDisease: Early Identification and Management of Chronic Kidney Disease inAdults in Primary and Secondary Care?

Output: Chronic KidneyDisease: Early Identiﬁcation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is KidneyDisease: Early Identification and Management of Chronic Kidney Disease inAdults in Primary and Secondary Care?. ### Response: Chronic KidneyDisease: Early Identiﬁcation.


Instruction: What is NICE Clinical Guideline 73?

Output: 2008.162

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE Clinical Guideline 73?. ### Response: 2008.162.


Instruction: How does Combining GFR and albuminuria improve prediction of ESRD?

Output: toclassify CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Combining GFR and albuminuria improve prediction of ESRD?. ### Response: toclassify CKD.


Instruction: What improves prediction of ESRD?

Output: Combining GFR and albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What improves prediction of ESRD?. ### Response: Combining GFR and albuminuria.


Instruction: What predicts cardiovascular and noncardiovascular mortality in general population?

Output: Urinary albumin excretion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts cardiovascular and noncardiovascular mortality in general population?. ### Response: Urinary albumin excretion.


Instruction: What predicts cardiovascular and noncardiovascular mortality in the general population?

Output: Urinary albumin excretion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts cardiovascular and noncardiovascular mortality in the general population?. ### Response: Urinary albumin excretion.


Instruction: What is the LIFE study?

Output: Albuminuria and cardiovascular riskin hypertensive patients with left ventricular hypertrophy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LIFE study?. ### Response: Albuminuria and cardiovascular riskin hypertensive patients with left ventricular hypertrophy.


Instruction: What did Sarnak MJ, Greene T, Wang X, et al. study the effect of a lower target blood pressure on the progression of kidney disease?

Output: long-term follow-up ofthe modiﬁcation of diet in renal disease study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Sarnak MJ, Greene T, Wang X, et al. study the effect of a lower target blood pressure on the progression of kidney disease?. ### Response: long-term follow-up ofthe modiﬁcation of diet in renal disease study.


Instruction: What did Ruilope LM, Salvetti A, Jamerson K, and Jamerson do?

Output: lowering of blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Ruilope LM, Salvetti A, Jamerson K, and Jamerson do?. ### Response: lowering of blood pressure.


Instruction: What does HOT stand for?

Output: hyperten-sion optimal treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HOT stand for?. ### Response: hyperten-sion optimal treatment.


Instruction: What is the name of the HOT study?

Output: hyperten-sion optimal treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the HOT study?. ### Response: hyperten-sion optimal treatment.


Instruction: When was the J Am Soc Nephrol 12:218–225.168?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Soc Nephrol 12:218–225.168?. ### Response: 2001.


Instruction: What did the Modification of Diet in Renal Disease Study study?

Output: lower target bloodpressure on the progression of kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Modification of Diet in Renal Disease Study study?. ### Response: lower target bloodpressure on the progression of kidney disease.


Instruction: When was KidneyInt published?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was KidneyInt published?. ### Response: 1997.


Instruction: What did Klahr S, Levey AS, Beck GJ et al. find the effects of?

Output: dietary protein restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Klahr S, Levey AS, Beck GJ et al. find the effects of?. ### Response: dietary protein restriction.


Instruction: How many small, randomized trials have been performed to date to examine the role of valve surgery in the management of IE?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many small, randomized trials have been performed to date to examine the role of valve surgery in the management of IE?. ### Response: 1.


Instruction: How many patients with left-sided NVE, severe valve regurury, and severe NVE were included in this trial?

Output: 76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with left-sided NVE, severe valve regurury, and severe NVE were included in this trial?. ### Response: 76.


Instruction: How many patients with left-sided NVE were assigned to early surgery within 48 hours or to conventional treatment?

Output: 76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with left-sided NVE were assigned to early surgery within 48 hours or to conventional treatment?. ### Response: 76.


Instruction: What percentage of in-hospital deaths and embolic events were reduced with early surgery?

Output: 3% versus 23%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of in-hospital deaths and embolic events were reduced with early surgery?. ### Response: 3% versus 23%),.


Instruction: What percentage of in-hospital deaths and embolic events were caused by early surgery?

Output: 3%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of in-hospital deaths and embolic events were caused by early surgery?. ### Response: 3%.


Instruction: What was the difference between the 2 groups driven by?

Output: a significant decrease in embolic events with early surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between the 2 groups driven by?. ### Response: a significant decrease in embolic events with early surgery.


Instruction: Why can't firm conclusions be drawn from this trial?

Output: small sample size of the study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why can't firm conclusions be drawn from this trial?. ### Response: small sample size of the study.


Instruction: What was the small sample size of the study?

Output: 76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the small sample size of the study?. ### Response: 76.


Instruction: What was a calculated risk of surgical mortality?

Output: EuroSCORE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a calculated risk of surgical mortality?. ### Response: EuroSCORE.


Instruction: How did the patients in this trial compare to other trials?

Output: lower mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the patients in this trial compare to other trials?. ### Response: lower mortality.


Instruction: What is a Class IIa indication for surgery?

Output: embolization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Class IIa indication for surgery?. ### Response: embolization.


Instruction: What is the low prevalence of S aureus IE compared with?

Output: lower mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the low prevalence of S aureus IE compared with?. ### Response: lower mortality.


Instruction: What does international collaboration251 support the notion252 that early valve surgery may not be beneficial in all patients with native or PVE caused by S aureus?

Output: Data from nonrandomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does international collaboration251 support the notion252 that early valve surgery may not be beneficial in all patients with native or PVE caused by S aureus?. ### Response: Data from nonrandomized trials.


Instruction: Over several decades, expert panels have relied on data from observational studies to make recommendations on indications for early surgery?

Output: 18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Over several decades, expert panels have relied on data from observational studies to make recommendations on indications for early surgery?. ### Response: 18.


Instruction: What have the indications for early surgery not changed appre-ciably over time?

Output: Despite the availability of new studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have the indications for early surgery not changed appre-ciably over time?. ### Response: Despite the availability of new studies.


Instruction: What are observational studies prone to?

Output: bias and confounding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are observational studies prone to?. ### Response: bias and confounding.


Instruction: How have researchers used regression analysis and calculated propensity scores?

Output: to adjust for prognostically important baseline differences between surgi-cal and medical patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How have researchers used regression analysis and calculated propensity scores?. ### Response: to adjust for prognostically important baseline differences between surgi-cal and medical patients.