Instruction: What is psoriasis?

Output: Incidence of cardio-vascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is psoriasis?. ### Response: Incidence of cardio-vascular disease.


Instruction: What is the name of the study that evaluated myocardial infarction risk estimation among patients with human immunodeficiency virus?

Output: Centers for AIDS Research Network of Integrated Clinical Systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated myocardial infarction risk estimation among patients with human immunodeficiency virus?. ### Response: Centers for AIDS Research Network of Integrated Clinical Systems.


Instruction: Who conducted the study?

Output: Centers for AIDS Research Network of Integrated Clinical Systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who conducted the study?. ### Response: Centers for AIDS Research Network of Integrated Clinical Systems.


Instruction: What is the name of the study that was conducted by the Centers for AIDS Research Network of Integrated Clinical Systems?

Output: Assessing and refin-ing myocardial infarction risk estimation among patients with human immunodeficiency virus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that was conducted by the Centers for AIDS Research Network of Integrated Clinical Systems?. ### Response: Assessing and refin-ing myocardial infarction risk estimation among patients with human immunodeficiency virus.


Instruction: What does the PCE estimate risk of hard ASCVD events (MI and stroke, both fatal and nonfatal)?

Output: S4.4.1.2-7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the PCE estimate risk of hard ASCVD events (MI and stroke, both fatal and nonfatal)?. ### Response: S4.4.1.2-7.


Instruction: What are Estimates readily applied in clinical practice?

Output: Esti-mates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Estimates readily applied in clinical practice?. ### Response: Esti-mates.


Instruction: What are the risk factors for estimates?

Output: age, cigarette smoking, blood pressure, serum TC, HDL-C, and presence or absence of diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risk factors for estimates?. ### Response: age, cigarette smoking, blood pressure, serum TC, HDL-C, and presence or absence of diabetes mellitus.


Instruction: Who are best validat-ed in race and sex-specific PCE?

Output: non-Hispanic blacks and non-Hispanic whites

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who are best validat-ed in race and sex-specific PCE?. ### Response: non-Hispanic blacks and non-Hispanic whites.


Instruction: Non-Hispanic whites 40 to 75 years of age?

Output: S4.4.1.2-1–S4.4.1,2-3,S4.4.1.2-7–S4.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Non-Hispanic whites 40 to 75 years of age?. ### Response: S4.4.1.2-1–S4.4.1,2-3,S4.4.1.2-7–S4.4.


Instruction: In other racial/ethnic groups, equations are less extensively studied what?

Output: stud-ied

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In other racial/ethnic groups, equations are less extensively studied what?. ### Response: stud-ied.


Instruction: Because the PCE are population equations, they may overestimate or underestimate risk for individu-als or population subgroups?

Output: Esti-mates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Because the PCE are population equations, they may overestimate or underestimate risk for individu-als or population subgroups?. ### Response: Esti-mates.


Instruction: What did the 2013 ACC/AHA guidelinesS4.4.1.2-5 identify as an RCT-supported threshold for benefit of statin therapy?

Output: 10-year risk of ASCVD ≥7.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2013 ACC/AHA guidelinesS4.4.1.2-5 identify as an RCT-supported threshold for benefit of statin therapy?. ### Response: 10-year risk of ASCVD ≥7.5%.


Instruction: What is the 10-year risk for ASCVD categorized as?

Output: ≥7.5%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 10-year risk for ASCVD categorized as?. ### Response: ≥7.5%..


Instruction: How long is the risk for ASCVD categorized?

Output: ≥7.5%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the risk for ASCVD categorized?. ### Response: ≥7.5%..


Instruction: What is the borderline risk?

Output: 5% to <7.5%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the borderline risk?. ### Response: 5% to <7.5%),.


Instruction: In adults 20 to 39 years, what can be used to inform intensity of treatment?

Output: assess-ment of 30-year or lifetime risk of a first ASCVD event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adults 20 to 39 years, what can be used to inform intensity of treatment?. ### Response: assess-ment of 30-year or lifetime risk of a first ASCVD event.


Instruction: What can be used to inform intensity of primary-prevention efforts?

Output: assess-ment of 30-year or lifetime risk of a first ASCVD event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to inform intensity of primary-prevention efforts?. ### Response: assess-ment of 30-year or lifetime risk of a first ASCVD event.


Instruction: How many online links can PCE estimates be calculated from?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many online links can PCE estimates be calculated from?. ### Response: 2.


Instruction: What allows for efficacious and cost-effective primary prevention?

Output: Moderate intensity generic statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What allows for efficacious and cost-effective primary prevention?. ### Response: Moderate intensity generic statins.


Instruction: What is the single most robust tool for esti-mating 10-year risk in US adults 40 to 75 years of age?

Output: pooled cohort equation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the single most robust tool for esti-mating 10-year risk in US adults 40 to 75 years of age?. ### Response: pooled cohort equation.


Instruction: What does PCE stand for?

Output: pooled cohort equation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PCE stand for?. ### Response: pooled cohort equation.


Instruction: What is one limitation of the PCE when applied to individuals?

Output: age counts as a risk factor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one limitation of the PCE when applied to individuals?. ### Response: age counts as a risk factor.


Instruction: What dominates risk scoring with advancing age?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What dominates risk scoring with advancing age?. ### Response: age.


Instruction: Age is a powerful population risk factor but does not necessarily reflect what?

Output: individual risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Age is a powerful population risk factor but does not necessarily reflect what?. ### Response: individual risk.


Instruction: What is a powerful population risk factor but does not necessarily reflect individual risk?

Output: Age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a powerful population risk factor but does not necessarily reflect individual risk?. ### Response: Age.


Instruction: What are baseline characteristics of populations called?

Output: baseline risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are baseline characteristics of populations called?. ### Response: baseline risk.


Instruction: Variation in baseline risk accounts for difference in risk in what?

Output: different ethnic groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Variation in baseline risk accounts for difference in risk in what?. ### Response: different ethnic groups.


Instruction: What accounts for difference in risk in different ethnic groups?

Output: Variation in baseline risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What accounts for difference in risk in different ethnic groups?. ### Response: Variation in baseline risk.


Instruction: Absolute risk predictions depend on the baseline risk of a population.

Output: non-Hispanic blacks and non-Hispanic whites 40 to 75 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Absolute risk predictions depend on the baseline risk of a population.. ### Response: non-Hispanic blacks and non-Hispanic whites 40 to 75 years of age.


Instruction: What leave room in the clinician-patient risk dis-tinction?

Output: patients at inter -mediate risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What leave room in the clinician-patient risk dis-tinction?. ### Response: patients at inter -mediate risk.


Instruction: What is the acronym for transcatheter aortic valve implantation?

Output: TAVI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for transcatheter aortic valve implantation?. ### Response: TAVI.


Instruction: What is the acronym for the African American Study of Kidney Disease and Hypertension?

Output: AASK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the African American Study of Kidney Disease and Hypertension?. ### Response: AASK.


Instruction: What type of blood pressure monitoring does the American College of Cardiology Foundation use?

Output: Ambulatory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of blood pressure monitoring does the American College of Cardiology Foundation use?. ### Response: Ambulatory.


Instruction: ACR Albumin/creatinine ratioADVANCE Action in Diabetes and Vascular Disease: Preteraxand Diamicron Modified Release ControlEvaluationAER Albumin excretion rateAHA American Heart AssociationALLHAT Antihypertensive and Lipid-Lowering Treatmentto Prevent Heart Attack TrialALTITUDE Aliskiren Trial in Type 2 Diabetes Using Cardio-vascular and Renal Disease EndpointsARB Angiotensin-receptor blockerBMI Body

Output: MDRD Modiﬁcation of Diet in Renal Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ACR Albumin/creatinine ratioADVANCE Action in Diabetes and Vascular Disease: Preteraxand Diamicron Modified Release ControlEvaluationAER Albumin excretion rateAHA American Heart AssociationALLHAT Antihypertensive and Lipid-Lowering Treatmentto Prevent Heart Attack TrialALTITUDE Aliskiren Trial in Type 2 Diabetes Using Cardio-vascular and Renal Disease EndpointsARB Angiotensin-receptor blockerBMI Body. ### Response: MDRD Modiﬁcation of Diet in Renal Disease.


Instruction: What are the endpoints for diabetes?

Output: Cardio-vascular and Renal Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the endpoints for diabetes?. ### Response: Cardio-vascular and Renal Disease.


Instruction: What is the body mass index of a diabetic?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the body mass index of a diabetic?. ### Response: BP.


Instruction: What is CKD 5D?

Output: Dialysis-dependent CKD 5CKiD Chronic Kidney Disease in Children

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD 5D?. ### Response: Dialysis-dependent CKD 5CKiD Chronic Kidney Disease in Children.


Instruction: What is the name of the conference on guideline standardization?

Output: COGS Conference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the conference on guideline standardization?. ### Response: COGS Conference.


Instruction: What is a direct renin inhibitor?

Output: DRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a direct renin inhibitor?. ### Response: DRI.


Instruction: What is an evidence review teamESCAPE Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients?

Output: Diabetes Interventions and ComplicationsDRI Direct renin inhibitorEDC Pittsburgh Epidemiology of Diabetes Complica-tions StudyERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an evidence review teamESCAPE Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients?. ### Response: Diabetes Interventions and ComplicationsDRI Direct renin inhibitorEDC Pittsburgh Epidemiology of Diabetes Complica-tions StudyERT.


Instruction: What is the GFR Glomerular filtration rateGRADE Grading of Recommendations Assessment,Development and EvaluationHOPE Heart Outcomes Prevention EvaluationHOT Hypertension Optimal TreatmentHR Hazard ratioHYVET Hypertension in the Very Elderly TrialICD International Classification of DiseasesIDNT Irbesartan Diabetic Nephropathy TrialINVEST International Verapamil SR Trandolapril studyJATOS Japanese Trial to AssessOptimal Systolic BloodPressure

Output: ﬁ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the GFR Glomerular filtration rateGRADE Grading of Recommendations Assessment,Development and EvaluationHOPE Heart Outcomes Prevention EvaluationHOT Hypertension Optimal TreatmentHR Hazard ratioHYVET Hypertension in the Very Elderly TrialICD International Classification of DiseasesIDNT Irbesartan Diabetic Nephropathy TrialINVEST International Verapamil SR Trandolapril studyJATOS Japanese Trial to AssessOptimal Systolic BloodPressure. ### Response: ﬁ.


Instruction: What is the name of the Japanese trial to assess optimum systolic blood pressure in elderly hypertensive patients?

Output: JATOS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Japanese trial to assess optimum systolic blood pressure in elderly hypertensive patients?. ### Response: JATOS.


Instruction: What is SR Trandolapril?

Output: INVEST International Verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SR Trandolapril?. ### Response: INVEST International Verapamil.


Instruction: What is the name of the study that modifies the diet in Renal Disease?

Output: MRFIT Multiple Risk Factor Intervention trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that modifies the diet in Renal Disease?. ### Response: MRFIT Multiple Risk Factor Intervention trial.


Instruction: What is a target of rapamycin?

Output: Mammalian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a target of rapamycin?. ### Response: Mammalian.


Instruction: What must progress in pre-venting stroke not lead to?

Output: complacency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must progress in pre-venting stroke not lead to?. ### Response: complacency.


Instruction: Why do several recommendations remain vague?

Output: suboptimal clinical trial evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do several recommendations remain vague?. ### Response: suboptimal clinical trial evidence.


Instruction: What is difficult to study with the same rigor as drugs or devices?

Output: Diet and exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is difficult to study with the same rigor as drugs or devices?. ### Response: Diet and exercise.


Instruction: What is easier to convince a patient to take a pill than to radically change his or her lifestyle?

Output: It is easier to convince a patient to take a pill than to radically change his or her lifestyle. Nonetheless, we must expect the same standards of evidence for lifestyle interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is easier to convince a patient to take a pill than to radically change his or her lifestyle?. ### Response: It is easier to convince a patient to take a pill than to radically change his or her lifestyle. Nonetheless, we must expect the same standards of evidence for lifestyle interventions.


Instruction: What are stents for carotid stenosis and occluders for PFO required to do?

Output: demonstrate favorable effects on patient-centered outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are stents for carotid stenosis and occluders for PFO required to do?. ### Response: demonstrate favorable effects on patient-centered outcomes.


Instruction: What should be required to demonstrate favorable effects on patient-centered outcomes such as preventing stroke?

Output: occluders for PFO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be required to demonstrate favorable effects on patient-centered outcomes such as preventing stroke?. ### Response: occluders for PFO.


Instruction: What would be seen as grossly undertreated medically by contemporary standards?

Output: The control groups of old that showed the benefits of CEA for asymptomatic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be seen as grossly undertreated medically by contemporary standards?. ### Response: The control groups of old that showed the benefits of CEA for asymptomatic stenosis.


Instruction: What would it be important to see if revas-cularization remains relevant in asymptomatic stenosis?

Output: a modern context

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would it be important to see if revas-cularization remains relevant in asymptomatic stenosis?. ### Response: a modern context.


Instruction: What is important to see if revas-cularization remains relevant in a modern context?

Output: It would be important to see if revas-cularization remains relevant in a modern context.Acknowledgments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to see if revas-cularization remains relevant in a modern context?. ### Response: It would be important to see if revas-cularization remains relevant in a modern context.Acknowledgments.


Instruction: Who helped with a sys-tematic review of the medical literature?

Output: Ann Farrell at Mayo Clinic Rochester and Tara Brigham at Mayo Clinic Florida

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who helped with a sys-tematic review of the medical literature?. ### Response: Ann Farrell at Mayo Clinic Rochester and Tara Brigham at Mayo Clinic Florida.


Instruction: What is not indicated for preventing stroke?

Output: Closure of patent foramen ovale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not indicated for preventing stroke?. ### Response: Closure of patent foramen ovale.


Instruction: What is not indicated for preventing stroke in patients with migraine?

Output: Closure of patent foramen ovale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not indicated for preventing stroke in patients with migraine?. ### Response: Closure of patent foramen ovale.


Instruction: What is reasonable for patients who abuse drugs that have been associated with stroke?

Output: Referral to an appropriate therapeutic program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for patients who abuse drugs that have been associated with stroke?. ### Response: Referral to an appropriate therapeutic program.


Instruction: What drugs are associated with stroke?

Output: cocaine, khat, and amphetamines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drugs are associated with stroke?. ### Response: cocaine, khat, and amphetamines.


Instruction: What is a class IIa; Level of Evidence C drug?

Output: amphetamines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIa; Level of Evidence C drug?. ### Response: amphetamines.


Instruction: What is a class IIb; Level of Evidence C?

Output: polysomnography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIb; Level of Evidence C?. ### Response: polysomnography.


Instruction: What has been downgraded to include polysomnography and specific questionnaires?

Output: Recommendation class and LOE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been downgraded to include polysomnography and specific questionnaires?. ### Response: Recommendation class and LOE.


Instruction: What is the clinical benefit of using lipoprotein(a) in stroke risk prediction not well established?

Output: Elevated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical benefit of using lipoprotein(a) in stroke risk prediction not well established?. ### Response: Elevated.


Instruction: What is a class IIb; Level of Evidence B?

Output: Elevated lipoprotein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIb; Level of Evidence B?. ### Response: Elevated lipoprotein.


Instruction: What class of risk might decrease stroke risk be considered?

Output: statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What class of risk might decrease stroke risk be considered?. ### Response: statin.


Instruction: What does the revised recommendation now define as >2.0 mg/dL in the context of considering statin initiation?

Output: elevated high-sensitivity C-reactive protein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the revised recommendation now define as >2.0 mg/dL in the context of considering statin initiation?. ### Response: elevated high-sensitivity C-reactive protein.


Instruction: What drugs have additive effects on lowering BP and are recommended as a primary therapy for pulmonary artery disease?

Output: beta blockers or clonidine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drugs have additive effects on lowering BP and are recommended as a primary therapy for pulmonary artery disease?. ### Response: beta blockers or clonidine.


Instruction: What is BP recommended as a primary therapy for?

Output: pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is BP recommended as a primary therapy for?. ### Response: pulmonary hypertension.


Instruction: What do some antihypertensive medications affect more than others?

Output: erectile dysfunc-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do some antihypertensive medications affect more than others?. ### Response: erectile dysfunc-tion.


Instruction: The use of what makes drug class distinctions for erectile dysfunction less relevant?

Output: phosphodiesterase-5 inhibi-tors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The use of what makes drug class distinctions for erectile dysfunction less relevant?. ### Response: phosphodiesterase-5 inhibi-tors.


Instruction: What has yet to be determined regarding the long-term safety and efficacy of phosphodiesterase-5 inhibitors?

Output: The long-term safety and efficacy of chronic administration of phosphodiesterase-5 inhibitors for the mit-igation of CVD has yet to be determined and represents an important knowledge gap

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has yet to be determined regarding the long-term safety and efficacy of phosphodiesterase-5 inhibitors?. ### Response: The long-term safety and efficacy of chronic administration of phosphodiesterase-5 inhibitors for the mit-igation of CVD has yet to be determined and represents an important knowledge gap.


Instruction: What represents an important knowledge gap?

Output: The long-term safety and efficacy of chronic administration of phosphodiesterase-5 inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What represents an important knowledge gap?. ### Response: The long-term safety and efficacy of chronic administration of phosphodiesterase-5 inhibitors.


Instruction: Where are references that support recommendations summarized?

Output: Online Data Supplements 57 and 58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are references that support recommendations summarized?. ### Response: Online Data Supplements 57 and 58.


Instruction: Where are procedures that support recommendations summarized?

Output: Online Data Supplements 57 and 58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are procedures that support recommendations summarized?. ### Response: Online Data Supplements 57 and 58.


Instruction: What should be continued in patients with hypertension who have been on beta blockers chronically?

Output: beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be continued in patients with hypertension who have been on beta blockers chronically?. ### Response: beta blockers.


Instruction: What is reasonable to continue medical therapy for for hypertension until surgery?

Output: planned elective major surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to continue medical therapy for for hypertension until surgery?. ### Response: planned elective major surgery.


Instruction: What can discontinuation of ACE inhibitors or ARBs perioperatively be considered in patients with hypertension?

Output: major surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can discontinuation of ACE inhibitors or ARBs perioperatively be considered in patients with hypertension?. ### Response: major surgery.


Instruction: In patients with planned elective major surgery, what is reasonable?

Output: to continue medical therapy for hypertension until surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with planned elective major surgery, what is reasonable?. ### Response: to continue medical therapy for hypertension until surgery.


Instruction: What is the risk of beta blockers or clonidine for patients undergoing surgery?

Output: potentially harmful

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of beta blockers or clonidine for patients undergoing surgery?. ### Response: potentially harmful.


Instruction: What should not be started on the day of surgery for patients with B-NR6?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be started on the day of surgery for patients with B-NR6?. ### Response: Beta blockers.


Instruction: If the patient has a DBP of 110 mm Hg or higher, what may be considered?

Output: deferring surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the patient has a DBP of 110 mm Hg or higher, what may be considered?. ### Response: deferring surgery.


Instruction: What should not be started on the day of surgery in beta blocker-nave patients?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be started on the day of surgery in beta blocker-nave patients?. ### Response: Beta blockers.


Instruction: What should patients with intraoperative hypertension be managed with until such time as oral medications can be resumed?

Output: intravenous medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with intraoperative hypertension be managed with until such time as oral medications can be resumed?. ### Response: intravenous medications.


Instruction: What increases the risk of CVD, cerebrovascular events, and bleeding?

Output: Hypertension in the perioperative period

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the risk of CVD, cerebrovascular events, and bleeding?. ### Response: Hypertension in the perioperative period.


Instruction: How many patients who undergo major noncar -diac surgery experience perioperative hypertension?

Output: 25%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients who undergo major noncar -diac surgery experience perioperative hypertension?. ### Response: 25%.


Instruction: What is the level of risk related to?

Output: the severity of the hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of risk related to?. ### Response: the severity of the hypertension.


Instruction: How is risk related to the severity of hypertension?

Output: the level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is risk related to the severity of hypertension?. ### Response: the level.


Instruction: When was this document downloaded?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this document downloaded?. ### Response: May 3, 2023.


Instruction: What is clopidogrel used for in patients with acute coronary syndromes requiring coronary artery bypass surgery?

Output: pre-operative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel used for in patients with acute coronary syndromes requiring coronary artery bypass surgery?. ### Response: pre-operative.


Instruction: What is the name of the multicenter study that evaluated the impact of a drug on patients with coronary heart syndromes?

Output: ACUITY(Acute Catheterization and Urgent Intervention Triage strategY) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter study that evaluated the impact of a drug on patients with coronary heart syndromes?. ### Response: ACUITY(Acute Catheterization and Urgent Intervention Triage strategY) trial.


Instruction: When was the J Am Coll Cardiol Med 2008 published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol Med 2008 published?. ### Response: 2009.


Instruction: What is clopidogrel used for inpatients with acute coronary syndromes undergoing coronary arterybypass surgery?

Output: Ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel used for inpatients with acute coronary syndromes undergoing coronary arterybypass surgery?. ### Response: Ticagrelor.


Instruction: What is PLATO?

Output: Platelet Inhibition andPatient Outcomes) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PLATO?. ### Response: Platelet Inhibition andPatient Outcomes) trial.


Instruction: When was the PLATO trial conducted?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the PLATO trial conducted?. ### Response: 2010.


Instruction: When given before coronary artery bypass grafting?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When given before coronary artery bypass grafting?. ### Response: clopidogrel.


Instruction: When was clopidogrel given?

Output: before coronary artery bypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was clopidogrel given?. ### Response: before coronary artery bypass grafting.


Instruction: What is postoperative bloodloss after pre-operative treatment?

Output: patients undergoing coronary artery bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is postoperative bloodloss after pre-operative treatment?. ### Response: patients undergoing coronary artery bypass surgery.


Instruction: What increases bloodtransfusion and hemorrhagic complications in patients undergoingcardiac surgery?

Output: Clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases bloodtransfusion and hemorrhagic complications in patients undergoingcardiac surgery?. ### Response: Clopidogrel.


Instruction: What does clopidogrel increase in patients underwent?

Output: cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does clopidogrel increase in patients underwent?. ### Response: cardiac surgery.


Instruction: When did Ann Thorac Surg. 2010 release 89:397–402.525?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ann Thorac Surg. 2010 release 89:397–402.525?. ### Response: 2010.


Instruction: What is the name of the drug that does not increase surgical bleeding afteremergency or urgent coronary artery bypass grafting?

Output: tirofibanhydrochloride

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that does not increase surgical bleeding afteremergency or urgent coronary artery bypass grafting?. ### Response: tirofibanhydrochloride.


Instruction: What is another name for Aggrastat?

Output: tirofibanhydrochloride

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Aggrastat?. ### Response: tirofibanhydrochloride.


Instruction: In what year was the J Thorac Car-diovasc Surg published?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the J Thorac Car-diovasc Surg published?. ### Response: 2001.


Instruction: What is eptifibatide used for?

Output: Immediate coronary arterybypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is eptifibatide used for?. ### Response: Immediate coronary arterybypass surgery.


Instruction: What is the name of the drug that inhibits platelet glycoprotein IIb/IIIa in unstable angina?

Output: Clopi-dogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that inhibits platelet glycoprotein IIb/IIIa in unstable angina?. ### Response: Clopi-dogrel.


Instruction: In what year was abciximab used?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was abciximab used?. ### Response: 2009.


Instruction: Abciximab and bleedingduring coronary surgery: results from the EPILOG and EPISTENTtrials?

Output: Lincoff AM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Abciximab and bleedingduring coronary surgery: results from the EPILOG and EPISTENTtrials?. ### Response: Lincoff AM.


Instruction: Improve Long-term Outcome with what?

Output: abciximab GP IIb/IIIablockade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Improve Long-term Outcome with what?. ### Response: abciximab GP IIb/IIIablockade.


Instruction: Evaluation of Platelet IIb/IIIa Inhibition in STENTing.

Output: AnnThorac Surg. 2000;70:516–26.529

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evaluation of Platelet IIb/IIIa Inhibition in STENTing.. ### Response: AnnThorac Surg. 2000;70:516–26.529.


Instruction: What is the ACUITY trial?

Output: Acute Catheterization and Urgent Intervention Triage strategY

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACUITY trial?. ### Response: Acute Catheterization and Urgent Intervention Triage strategY.


Instruction: What are the benefits and risks of the combi-nation of clopidogrel and aspirin?

Output: benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the benefits and risks of the combi-nation of clopidogrel and aspirin?. ### Response: benefits.


Instruction: What is the combi-nation of clopidogrel and aspirin in patients undergoing surgical revas-cularization for non-ST-elevation acute coronary syndrome?

Output: benefits and risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the combi-nation of clopidogrel and aspirin in patients undergoing surgical revas-cularization for non-ST-elevation acute coronary syndrome?. ### Response: benefits and risks.


Instruction: What does the Clopi-dogrel in Unstable angina to prevent Recurrent ischemic Events(CURE) Trial) do?

Output: benefits and risks of the combi-nation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Clopi-dogrel in Unstable angina to prevent Recurrent ischemic Events(CURE) Trial) do?. ### Response: benefits and risks of the combi-nation.


Instruction: What type of surgery is used for coronary artery bypass graft surgery?

Output: urgent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery is used for coronary artery bypass graft surgery?. ### Response: urgent.


Instruction: When was the ACCF/AHA CABG Guideline e713 published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ACCF/AHA CABG Guideline e713 published?. ### Response: 2011.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?

Output: Page 23 of 134 VII

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?. ### Response: Page 23 of 134 VII.


Instruction: What do we recommend screening for elevated blood pressure periodically?

Output: Screening  1. We recommend screening adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we recommend screening for elevated blood pressure periodically?. ### Response: Screening  1. We recommend screening adults.


Instruction: What are we suggesting using?

Output: out -of-office blood pressure  monitoring methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are we suggesting using?. ### Response: out -of-office blood pressure  monitoring methods.


Instruction: How long does it take to take an automated blood pressure measurement to take place?

Output: five minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to take an automated blood pressure measurement to take place?. ### Response: five minutes.


Instruction: How long does it take to record a blood pressure measurement?

Output: five minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to record a blood pressure measurement?. ### Response: five minutes.


Instruction: How long is it to record the average of three measurements separated by at least 30 seconds?

Output: five minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it to record the average of three measurements separated by at least 30 seconds?. ### Response: five minutes.


Instruction: What do we suggest when automated blood pressure measurements are not available?

Output: measurement of blood pressure using standard technique and a properly calibrated and validated sphygmomanometer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest when automated blood pressure measurements are not available?. ### Response: measurement of blood pressure using standard technique and a properly calibrated and validated sphygmomanometer.


Instruction: What do we suggest using out-of-office blood pressure monitoring methods to inform the diagnosis and management of?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest using out-of-office blood pressure monitoring methods to inform the diagnosis and management of?. ### Response: hypertension.


Instruction: What is the diagnosis and management of hypertension?

Output: General Approaches to Hypertension Management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diagnosis and management of hypertension?. ### Response: General Approaches to Hypertension Management.


Instruction: What do patients treated for hypertension suggest offering home blood pressure self -monitoring with co-interventions?

Output: lowering systolic and diastolic blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients treated for hypertension suggest offering home blood pressure self -monitoring with co-interventions?. ### Response: lowering systolic and diastolic blood pressure.


Instruction: What is the systolic blood pressure goal for type 2 diabetes?

Output: <140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic blood pressure goal for type 2 diabetes?. ### Response: <140 mm Hg.


Instruction: What is a weak for Reviewed, New-added Treatment Goals and General Approaches?

Output: Blood Pressure Goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a weak for Reviewed, New-added Treatment Goals and General Approaches?. ### Response: Blood Pressure Goals.


Instruction: What is the systolic blood pressure goal?

Output: <130 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic blood pressure goal?. ### Response: <130 mm Hg.


Instruction: For patients 60 years and over, what is recommended?

Output: treating to a systolic blood pressure goal of <150 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients 60 years and over, what is recommended?. ### Response: treating to a systolic blood pressure goal of <150 mm Hg.


Instruction: What is the systolic blo od pressure goal for patients 60 years and over with type 2 diabetes?

Output: <140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic blo od pressure goal for patients 60 years and over with type 2 diabetes?. ### Response: <140 mm Hg.


Instruction: What is a strong for Reviewed, Amended 8?

Output: Hg and 150 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strong for Reviewed, Amended 8?. ### Response: Hg and 150 mm Hg.


Instruction: What is the systolic blo od pressure goal?

Output: <140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic blo od pressure goal?. ### Response: <140 mm Hg.


Instruction: What is a dded benefit to lowering the blood pressure further for those between 130 and 140mm Hg?

Output: systolic blo od pressure goal of <140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a dded benefit to lowering the blood pressure further for those between 130 and 140mm Hg?. ### Response: systolic blo od pressure goal of <140 mm Hg.


Instruction: For patients 30 years and over, we recommend treating to what?

Output: diastolic blood pressure goal of <90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients 30 years and over, we recommend treating to what?. ### Response: diastolic blood pressure goal of <90 mm Hg.


Instruction: What is the diastolic blood pressure goal?

Output: <90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diastolic blood pressure goal?. ### Response: <90 mm Hg.


Instruction: How old is the patient?

Output: 60 years and over

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is the patient?. ### Response: 60 years and over.


Instruction: What can be effective for acute treatment in ACHD patients and SVT?

Output: Atrial pacing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be effective for acute treatment in ACHD patients and SVT?. ### Response: Atrial pacing.


Instruction: What is hemodynamically stable and anticoagulated as per current guidelines for antithrombotic therapy in patients with AF?

Output: SVT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hemodynamically stable and anticoagulated as per current guidelines for antithrombotic therapy in patients with AF?. ### Response: SVT.


Instruction: Atrial pacing is an effective alternative when concerns about what exist?

Output: the use of antiarrhythmic medications or significant sinus node dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial pacing is an effective alternative when concerns about what exist?. ### Response: the use of antiarrhythmic medications or significant sinus node dysfunction.


Instruction: What can be useful for patients with AT or atrial flutter?

Output: Elective synchronized cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be useful for patients with AT or atrial flutter?. ### Response: Elective synchronized cardioversion.


Instruction: What can be useful for acute termination of AT or atrial flutter in ACHD patients when pharmacological therapy is ineffective or contraindicated?

Output: Elective synchronized cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be useful for acute termination of AT or atrial flutter in ACHD patients when pharmacological therapy is ineffective or contraindicated?. ### Response: Elective synchronized cardioversion.


Instruction: Patients with ACHD are at increased risk of what?

Output: congestive heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with ACHD are at increased risk of what?. ### Response: congestive heart failure.


Instruction: Atrial thrombus formation with prolonged episodes of AT or atrial flutter?

Output: Online Data Supplement 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial thrombus formation with prolonged episodes of AT or atrial flutter?. ### Response: Online Data Supplement 20.


Instruction: Pharmacological conversion in patients with complex anatomy, ventricular dysfunction, or prolonged QTc intervals may result in what?

Output: significant proarrhythmia or acute hemodynamic deterioration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pharmacological conversion in patients with complex anatomy, ventricular dysfunction, or prolonged QTc intervals may result in what?. ### Response: significant proarrhythmia or acute hemodynamic deterioration.


Instruction: What may be preferable to early assessment for cardiac thrombosis?

Output: Atrial pacing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be preferable to early assessment for cardiac thrombosis?. ### Response: Atrial pacing.


Instruction: What may be preferable to prolonged or multiple attempts to achieve pharmacological cardioversion?

Output: esophageal echocardiogram followed by synchronized cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be preferable to prolonged or multiple attempts to achieve pharmacological cardioversion?. ### Response: esophageal echocardiogram followed by synchronized cardioversion.


Instruction: Because of frequent coexistent sinus node dysfunction and ventricular dysfunction, what should be anticipated?

Output: the need for chronotropic or inotropic intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Because of frequent coexistent sinus node dysfunction and ventricular dysfunction, what should be anticipated?. ### Response: the need for chronotropic or inotropic intervention.


Instruction: What configuration may be necessary in patients with marked atrial enlargement?

Output: anterior-posterior

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What configuration may be necessary in patients with marked atrial enlargement?. ### Response: anterior-posterior.


Instruction: What may be reasonable for acute treatment in ACHD patients and AT and/or atrial flutter who are hemodynamically stable?

Output: Oral dofetilide or sotalol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable for acute treatment in ACHD patients and AT and/or atrial flutter who are hemodynamically stable?. ### Response: Oral dofetilide or sotalol.


Instruction: What are patients with AT and/or atrial flutter who are hemodynamically stable?

Output: ACHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with AT and/or atrial flutter who are hemodynamically stable?. ### Response: ACHD.


Instruction: What do small observational studies support the use of oral dofetilide474 or sotalol473 to acutely convert AT to sinus rhythm?

Output: 70% to 85% of episodes of acute AT or atrial flutter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do small observational studies support the use of oral dofetilide474 or sotalol473 to acutely convert AT to sinus rhythm?. ### Response: 70% to 85% of episodes of acute AT or atrial flutter.


Instruction: What is more commonly reported with dofetilide?

Output: ythmic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more commonly reported with dofetilide?. ### Response: ythmic events.


Instruction: What is the risk of proarrhythmia or worsening ventricular function?

Output: requires arrhythmia monitoring with use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of proarrhythmia or worsening ventricular function?. ### Response: requires arrhythmia monitoring with use.


Instruction: How many patients reported that 10% experienced torsades de pointes after what?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients reported that 10% experienced torsades de pointes after what?. ### Response: 20.


Instruction: What does worsening ventricular function require?

Output: arrhythmia monitoring with use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does worsening ventricular function require?. ### Response: arrhythmia monitoring with use.


Instruction: What is required to monitor arrhythmias?

Output: The risk of proarrhythmia or worsening ventricular function requires arrhythmia monitoring with use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required to monitor arrhythmias?. ### Response: The risk of proarrhythmia or worsening ventricular function requires arrhythmia monitoring with use.


Instruction: When were the recommendations for acute treatment of SVT in ACHD patients downloaded?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were the recommendations for acute treatment of SVT in ACHD patients downloaded?. ### Response: April 23, 2023.


Instruction: What type of angiography can be performed on patients with AMI who are managed conservatively?

Output: invasive coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of angiography can be performed on patients with AMI who are managed conservatively?. ### Response: invasive coronary angiography.


Instruction: What is one of the common clinical indications for resorting to coronary angiogram during the same AMI hospitalization after an initial conservative management trial?

Output: spontaneous non-inducible ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the common clinical indications for resorting to coronary angiogram during the same AMI hospitalization after an initial conservative management trial?. ### Response: spontaneous non-inducible ischemia.


Instruction: What is LVSD?

Output: left ventricular systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LVSD?. ### Response: left ventricular systolic dysfunction.


Instruction: What are the scenarios to be differentiated from?

Output: those during which coronary angiography is performed in initially conservatively managed AMI patients because of a high-risk noninvasive stress test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the scenarios to be differentiated from?. ### Response: those during which coronary angiography is performed in initially conservatively managed AMI patients because of a high-risk noninvasive stress test.


Instruction: What should be performed before noninvasive testing for ischemia?

Output: discharge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed before noninvasive testing for ischemia?. ### Response: discharge.


Instruction: What should not be performed in initially conservatively managed AMI patients?

Output: coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be performed in initially conservatively managed AMI patients?. ### Response: coronary angiography.


Instruction: What should be performed before discharge to assess the presence and extent of inducible ischemia in patients with STEMI who have not had coronary angiography and do not have high-risk clinical features?

Output: Noninvasive testing for ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed before discharge to assess the presence and extent of inducible ischemia in patients with STEMI who have not had coronary angiography and do not have high-risk clinical features?. ### Response: Noninvasive testing for ischemia.


Instruction: What is the class I, Level of Evidence: B?

Output: 54–57,139

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class I, Level of Evidence: B?. ### Response: 54–57,139.


Instruction: What would be warranted?

Output: coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be warranted?. ### Response: coronary angiography.


Instruction: What is recommended in low- and intermediate-risk patients who have been free of ischemia at rest or with low-level activity for a minimum of 12 months?

Output: Noninvasive stress testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in low- and intermediate-risk patients who have been free of ischemia at rest or with low-level activity for a minimum of 12 months?. ### Response: Noninvasive stress testing.


Instruction: What does ACC stand for?

Output: American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACC stand for?. ### Response: American College of Cardiology.


Instruction: What is ACCF standing for? What is LVSD standing for??

Output: left ventricular systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACCF standing for? What is LVSD standing for??. ### Response: left ventricular systolic dysfunction.


Instruction: How long should you rest or with low-level activity for a minimum of?

Output: 12 to 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should you rest or with low-level activity for a minimum of?. ### Response: 12 to 24 hours.


Instruction: What is STEMI?

Output: ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is STEMI?. ### Response: ST-elevation myocardial infarction.


Instruction: What is ST-elevation myocardial infarction?

Output: STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ST-elevation myocardial infarction?. ### Response: STEMI.


Instruction: When was Appendix A downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Appendix A downloaded?. ### Response: April 28, 2023.


Instruction: What is the Chicago Heart Association's Detection Project in Industry?

Output: Relationship of blood pressure to 25-year mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Chicago Heart Association's Detection Project in Industry?. ### Response: Relationship of blood pressure to 25-year mortality.


Instruction: When was the Arch Intern Med published?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Arch Intern Med published?. ### Response: 2001.


Instruction: How long did it take to die from heart disease in young adult men?

Output: 25-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to die from heart disease in young adult men?. ### Response: 25-year.


Instruction: What was the name of the project in 2001?

Output: Chicago Heart Association Detection Project in Industry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the project in 2001?. ### Response: Chicago Heart Association Detection Project in Industry.


Instruction: What are events due to elevated blood pressure due to?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are events due to elevated blood pressure due to?. ### Response: mortality.


Instruction: What is the name of the study that examined the outcomes of black and white hypertensive individuals after 30 years of follow-up?

Output: Charleston Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the outcomes of black and white hypertensive individuals after 30 years of follow-up?. ### Response: Charleston Heart Study.


Instruction: What is the name of the study that compares blacks and whites for high brachial pulse pressure?

Output: Charleston Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares blacks and whites for high brachial pulse pressure?. ### Response: Charleston Heart Study.


Instruction: What are the names of the studies that compare blacks with whites?

Output: Charleston Heart Study, Evans County Study, NHANES I and II Studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the studies that compare blacks with whites?. ### Response: Charleston Heart Study, Evans County Study, NHANES I and II Studies.


Instruction: When was the Am J Cardiol. 102?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol. 102?. ### Response: 2008.


Instruction: What is the name of the group that studied the effects of ACE inhibitors, cal-cium antagonists, and other blood-pressure-lowering drugs?

Output: HYVET Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studied the effects of ACE inhibitors, cal-cium antagonists, and other blood-pressure-lowering drugs?. ### Response: HYVET Study Group.


Instruction: When did Blood Pressure Lowering Treatment Trialists' Collaboration appear in the Lancet?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Blood Pressure Lowering Treatment Trialists' Collaboration appear in the Lancet?. ### Response: 2000.


Instruction: What is the name of the population-based prospective study that found no association between high blood pressure and mortality after age 85 years?

Output: J Hypertens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the population-based prospective study that found no association between high blood pressure and mortality after age 85 years?. ### Response: J Hypertens.


Instruction: What is the name of the study group that studies the treatment of hypertension in patients 80 years of age or older?

Output: HYVET Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studies the treatment of hypertension in patients 80 years of age or older?. ### Response: HYVET Study Group.


Instruction: What year did the N Engl J Med issue 358:1887-1898?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the N Engl J Med issue 358:1887-1898?. ### Response: 2008.


Instruction: What is ramipril?

Output: angiotensin-converting-enzyme inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ramipril?. ### Response: angiotensin-converting-enzyme inhibitor.


Instruction: What is the name of the angiotensin-converting-enzyme inhibitor?

Output: ramipril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the angiotensin-converting-enzyme inhibitor?. ### Response: ramipril.


Instruction: Where is the MediCiti Medical College located?

Output: Hyderabad/India

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the MediCiti Medical College located?. ### Response: Hyderabad/India.


Instruction: What is the name of the medical school in Huntington, WV?

Output: Marshall University

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the medical school in Huntington, WV?. ### Response: Marshall University.


Instruction: Where is the Hattiesburg Clinic located?

Output: Hattiesburg, MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Hattiesburg Clinic located?. ### Response: Hattiesburg, MS.


Instruction: What school of medicine is located at Marshall University?

Output: Joan C. Edwards School  of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What school of medicine is located at Marshall University?. ### Response: Joan C. Edwards School  of Medicine.


Instruction: What is the name of the clinic in Hattiesburg, MSN?

Output: Thad F. Waites Hattiesburg Clinic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the clinic in Hattiesburg, MSN?. ### Response: Thad F. Waites Hattiesburg Clinic.


Instruction: Who is the CEO of New York University Medical Center?

Output: Howard S. Weintraub

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the CEO of New York University Medical Center?. ### Response: Howard S. Weintraub.


Instruction: What are the names of the companies that are listed on the Disclosure Questionnaire?

Output: raZeneca†; Daiichi Sankyo*; Takeda†; Abbott†; Kowa*; Novartis†None None None None

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the companies that are listed on the Disclosure Questionnaire?. ### Response: raZeneca†; Daiichi Sankyo*; Takeda†; Abbott†; Kowa*; Novartis†None None None None.


Instruction: What are perceived conflicts of interest reported on?

Output: Disclosure Questionnaire

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are perceived conflicts of interest reported on?. ### Response: Disclosure Questionnaire.


Instruction: What is a relationship considered to be if a person receives $10 000 or more during a 12-month period?

Output: significant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if a person receives $10 000 or more during a 12-month period?. ### Response: significant.


Instruction: What percentage of the person’s gross income does the person own?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the person’s gross income does the person own?. ### Response: 5%.


Instruction: How much of the entity’s voting stock or share is the person entitled to?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the entity’s voting stock or share is the person entitled to?. ### Response: 5%.


Instruction: What type of sleep apnea can be treated with patiromer?

Output: severe obstructive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of sleep apnea can be treated with patiromer?. ### Response: severe obstructive.


Instruction: What is ACEI 14angiotensin-converting enzyme?

Output: inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACEI 14angiotensin-converting enzyme?. ### Response: inhibitors.


Instruction: What is the name of the ACEI 14angiotensin-converting enzyme inhibitor?

Output: ARNI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACEI 14angiotensin-converting enzyme inhibitor?. ### Response: ARNI.


Instruction: What is a name for a ADA14American Diabetes Association?

Output: ADA ¼

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a name for a ADA14American Diabetes Association?. ### Response: ADA ¼.


Instruction: How is GDMT 14"guideline-directed medical therapy?

Output: ¼

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is GDMT 14"guideline-directed medical therapy?. ### Response: ¼.


Instruction: HFrEF 14heart failure with reduced ejection fraction?

Output: ¼

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HFrEF 14heart failure with reduced ejection fraction?. ### Response: ¼.


Instruction: What is the acronym for Heart Rhythm Society?

Output: HRS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Heart Rhythm Society?. ### Response: HRS.


Instruction: What is the date of the update to 2017 ECDP for Optimization of Heart Failure Treatment?

Output: FEBRUARY 16, 2021:772 –810 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the date of the update to 2017 ECDP for Optimization of Heart Failure Treatment?. ### Response: FEBRUARY 16, 2021:772 –810 2021.


Instruction: How many patients with hypertension were included in the study?

Output: 13 844

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with hypertension were included in the study?. ### Response: 13 844.


Instruction: What is the name of the study that examined the effect of daytime and nighttime systolic blood pressure on the patient's health?

Output: S4.3-15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the effect of daytime and nighttime systolic blood pressure on the patient's health?. ### Response: S4.3-15.


Instruction: Which group of patients had a higher risk of hypertension?

Output: white-coat, masked and sustained hypertension versus true normo-tension: a meta-analysis. J Hypertens. 2007;25:2193–8. S4.4-5. National Clinical Guideline Centre (UK). Hypertension: The Clinical Management of Primary Hypertension in Adults: Update of Clinical Guidelines 18 and 34. London, UK: Royal College of Physicians (UK); 2011. S4.4-6. Asayama K, Thijs L, Li Y , et al. Setting thresholds to varying blood pressure monitoring intervals differentially affects risk estimates associated with white-coat and masked hypertension in the popula-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which group of patients had a higher risk of hypertension?. ### Response: white-coat, masked and sustained hypertension versus true normo-tension: a meta-analysis. J Hypertens. 2007;25:2193–8. S4.4-5. National Clinical Guideline Centre (UK). Hypertension: The Clinical Management of Primary Hypertension in Adults: Update of Clinical Guidelines 18 and 34. London, UK: Royal College of Physicians (UK); 2011. S4.4-6. Asayama K, Thijs L, Li Y , et al. Setting thresholds to varying blood pressure monitoring intervals differentially affects risk estimates associated with white-coat and masked hypertension in the popula-tion.


Instruction: What is the long-term risk of sustained hypertension in white-coat or masked hypertension?

Output: cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term risk of sustained hypertension in white-coat or masked hypertension?. ### Response: cardiovascular events.


Instruction: What does Ben-Dov IZ, Ben-Arie L, Mekler J, et al. do in ambulatory BP monitoring?

Output: Reproducibility of white-coat and masked hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Ben-Dov IZ, Ben-Arie L, Mekler J, et al. do in ambulatory BP monitoring?. ### Response: Reproducibility of white-coat and masked hypertension.


Instruction: Int J Cardiol. 2007;117:355–9.

Output: -Dov IZ, Ben-Arie L, Mekler J, et al. Reproducibility of white-coat and masked hypertension in ambulatory BP monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol. 2007;117:355–9.. ### Response: -Dov IZ, Ben-Arie L, Mekler J, et al. Reproducibility of white-coat and masked hypertension in ambulatory BP monitoring.


Instruction: What is a prehypertensive state?

Output: Isolated office hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prehypertensive state?. ### Response: Isolated office hypertension.


Instruction: What is an appropriate time inter val to repeat ambulatory blood pressure monitoring in white-coat resistant hypertension?

Output: 24-h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an appropriate time inter val to repeat ambulatory blood pressure monitoring in white-coat resistant hypertension?. ### Response: 24-h.


Instruction: How long did a prospective study of masked hypertension last?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did a prospective study of masked hypertension last?. ### Response: 5-year.


Instruction: What type of hypertension is present in young subjects screened for stage 1 hypertension?

Output: isolated ambulatory hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypertension is present in young subjects screened for stage 1 hypertension?. ### Response: isolated ambulatory hypertension.


Instruction: What is a risk factor for the development of home hypertension?

Output: White-coat hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for the development of home hypertension?. ### Response: White-coat hypertension.


Instruction: When was the Ohasama study conducted?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ohasama study conducted?. ### Response: 2005.


Instruction: How common is white coat hypertension?

Output: S4.4-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How common is white coat hypertension?. ### Response: S4.4-2.


Instruction: What is the name of the systematic review for blood pressure screening methods with consideration of rescreening intervals?

Output: U.S. Preventive Services Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review for blood pressure screening methods with consideration of rescreening intervals?. ### Response: U.S. Preventive Services Task Force.


Instruction: What did the U.S. Preventive Services Task Force do?

Output: a systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the U.S. Preventive Services Task Force do?. ### Response: a systematic review.


Instruction: What was the name of the systematic review?

Output: U.S. Preventive Services Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic review?. ### Response: U.S. Preventive Services Task Force.


Instruction: How long did the Ohasama study follow-up?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Ohasama study follow-up?. ### Response: 10-year.


Instruction: How long did the Ohasama study last?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Ohasama study last?. ### Response: 10-year.


Instruction: What did Fagard RH, Cornelissen V A do?

Output: Incidence of cardiovascular events in white-coat, masked and sustained hypertension versus true normo-tension: a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Fagard RH, Cornelissen V A do?. ### Response: Incidence of cardiovascular events in white-coat, masked and sustained hypertension versus true normo-tension: a meta-analysis.


Instruction: Incidence of cardiovascular events in white-coat, masked and sustained hypertension versus true normo-tension: a meta-analysis?

Output: Fagard

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Incidence of cardiovascular events in white-coat, masked and sustained hypertension versus true normo-tension: a meta-analysis?. ### Response: Fagard.


Instruction: Where is the Clinical Guideline Centre located?

Output: UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Clinical Guideline Centre located?. ### Response: UK.


Instruction: What does the Clinical Management of Primary Hypertension in Adults: Update of Clinical Guidelines 18 and 34 do?

Output: Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Clinical Management of Primary Hypertension in Adults: Update of Clinical Guidelines 18 and 34 do?. ### Response: Hypertension.


Instruction: When did the Royal College of Physicians publish the Hypertension Handbook?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Royal College of Physicians publish the Hypertension Handbook?. ### Response: 2011.


Instruction: What affects risk estimates associated with white-coat and masked hypertension in the popula-tion?

Output: Setting thresholds to varying blood pressure monitoring intervals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What affects risk estimates associated with white-coat and masked hypertension in the popula-tion?. ### Response: Setting thresholds to varying blood pressure monitoring intervals.


Instruction: How does varying blood pressure monitoring intervals affect risk estimates?

Output: differentially

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does varying blood pressure monitoring intervals affect risk estimates?. ### Response: differentially.


Instruction: What is the long-term prognostic value of white coat hypertension?

Output: an insight from diagnostic use of both ambulatory and home blood pressure measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term prognostic value of white coat hypertension?. ### Response: an insight from diagnostic use of both ambulatory and home blood pressure measurements.


Instruction: How does the r ecommenda tions mig ht affect practice?

Output: unlik ely to be substantial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the r ecommenda tions mig ht affect practice?. ### Response: unlik ely to be substantial.


Instruction: How will people wit h emer gency sympt oms benefit fr ost ur gent tr eatment?

Output: because accelerat ed hyper tension can be f atal if untr eated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How will people wit h emer gency sympt oms benefit fr ost ur gent tr eatment?. ### Response: because accelerat ed hyper tension can be f atal if untr eated.


Instruction: Why can accelerat ed hyper tension be f atal if untr eated?

Output: Ho wever, people wit h emer gency sympt oms will benefit fr om ur gent tr eatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why can accelerat ed hyper tension be f atal if untr eated?. ### Response: Ho wever, people wit h emer gency sympt oms will benefit fr om ur gent tr eatment.


Instruction: What would be some additional use fr om doing tar get or gan damage to ests mor e quickly?

Output: Ther e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be some additional use fr om doing tar get or gan damage to ests mor e quickly?. ### Response: Ther e.


Instruction: How long did it take for blood to be measured?

Output: 7  days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for blood to be measured?. ### Response: 7  days.


Instruction: Why did people start on tr eatment immediatly?

Output: under taking in vestigations first

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did people start on tr eatment immediatly?. ### Response: under taking in vestigations first.


Instruction: What is the population wit h severe hyper tension?

Output: small

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population wit h severe hyper tension?. ### Response: small.


Instruction: The population wit h severe hyper tension is v ery small, and t he pr opor tion with severe hypertension and additional sympt oms that suggest accelerat ed hyper tension are e ven smaller, what is t herefore unlik ely to be substantial?

Output: resour ce impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The population wit h severe hyper tension is v ery small, and t he pr opor tion with severe hypertension and additional sympt oms that suggest accelerat ed hyper tension are e ven smaller, what is t herefore unlik ely to be substantial?. ### Response: resour ce impact.


Instruction: What is unlik ely to be substantial?

Output: resour ce impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unlik ely to be substantial?. ### Response: resour ce impact.


Instruction: What is Hyper tension in adult s: diagnosis and management?

Output: NG136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Hyper tension in adult s: diagnosis and management?. ### Response: NG136.


Instruction: What is often present among patients with VHD1–4?

Output: CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often present among patients with VHD1–4?. ### Response: CAD.


Instruction: Knowledge of what contributes to risk stratification?

Output: coronary anatomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Knowledge of what contributes to risk stratification?. ### Response: coronary anatomy.


Instruction: What is a low prevalence of CAD among men 40 years of age?

Output: <40 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a low prevalence of CAD among men 40 years of age?. ### Response: <40 years of age.


Instruction: Low prevalence of CAD among men 40 years of age and premenopausal women with no athero-sclerotic risk factors2,5–7 or history of mediastinal radiation?

Output: low prevalence of CAD among men <40 years of age and premenopausal women with no athero-sclerotic risk factors2,5–7 or history of mediastinal radiation.82

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Low prevalence of CAD among men 40 years of age and premenopausal women with no athero-sclerotic risk factors2,5–7 or history of mediastinal radiation?. ### Response: low prevalence of CAD among men <40 years of age and premenopausal women with no athero-sclerotic risk factors2,5–7 or history of mediastinal radiation.82.


Instruction: Functional MR occurs in patients with structur ally normal valve leaflets and chordae because of what?

Output: LV dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Functional MR occurs in patients with structur ally normal valve leaflets and chordae because of what?. ### Response: LV dysfunction.


Instruction: What may be attributable to CAD and accompanying myocardial ischemia?

Output: LV dys-function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be attributable to CAD and accompanying myocardial ischemia?. ### Response: LV dys-function.


Instruction: What is necessary to complete the diagnosis of LV dys-function?

Output: the assessment of coronary anatomy status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is necessary to complete the diagnosis of LV dys-function?. ### Response: the assessment of coronary anatomy status.


Instruction: What is necessary to complete the diagnosis and allow evaluation of revascularization options?

Output: the assessment of coronary anatomy status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is necessary to complete the diagnosis and allow evaluation of revascularization options?. ### Response: the assessment of coronary anatomy status.


Instruction: Contrast-enhanced coronary CT angiography is an alternative to what?

Output: coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Contrast-enhanced coronary CT angiography is an alternative to what?. ### Response: coronary angiography.


Instruction: Who should have a selective coronary angi-ography before valve surgery?

Output: patients who have active symptoms of angina, those with documented ischemia, or those with a prior history of CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should have a selective coronary angi-ography before valve surgery?. ### Response: patients who have active symptoms of angina, those with documented ischemia, or those with a prior history of CAD.


Instruction: Recent studies have demonstrated diagnostic sensitivity of what?

Output: >90%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent studies have demonstrated diagnostic sensitivity of what?. ### Response: >90%,.


Instruction: How much diagnostic sensitivity do pre-TAVI evaluations show?

Output: >90%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much diagnostic sensitivity do pre-TAVI evaluations show?. ### Response: >90%,.


Instruction: What percentage of specificity does TAVI evaluation demonstrate?

Output: 60% to 90%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of specificity does TAVI evaluation demonstrate?. ### Response: 60% to 90%,.


Instruction: Contrast-enhanced coronary CT angiography may be safer than what?

Output: coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Contrast-enhanced coronary CT angiography may be safer than what?. ### Response: coronary angiography.


Instruction: What is a positive con-trast-enhanced coronary CT angiogram defined as?

Output: the presence of epicardial CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a positive con-trast-enhanced coronary CT angiogram defined as?. ### Response: the presence of epicardial CAD.


Instruction: What is required to establish the need for and extent of CABG?

Output: invasive coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required to establish the need for and extent of CABG?. ### Response: invasive coronary angiography.


Instruction: The risk of radiation exposure and renal failure should be taken because of what?

Output: the contrast injection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The risk of radiation exposure and renal failure should be taken because of what?. ### Response: the contrast injection.


Instruction: What should be taken into consideration?

Output: coronary anatomy status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be taken into consideration?. ### Response: coronary anatomy status.


Instruction: What has been shown to negatively impact both perioperative22,23 and late outcomes of surgery for VHD?

Output: The presence of uncorrected CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to negatively impact both perioperative22,23 and late outcomes of surgery for VHD?. ### Response: The presence of uncorrected CAD.


Instruction: Concomitant CABG has been favored what?

Output: These stud-ies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Concomitant CABG has been favored what?. ### Response: These stud-ies.


Instruction: What has shown little or no adverse impact on the acute perioperative mortality rate?

Output: stud-ies of concomitant CABG at the time of valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has shown little or no adverse impact on the acute perioperative mortality rate?. ### Response: stud-ies of concomitant CABG at the time of valve surgery.