Instruction: What is the name of the randomized, placebo-controlled, randomized clinical trial of dietary flaxseed supplementation for children and adolescents with hypercholesterolemia?

Output: Flaxseed in pediatric hyper -lipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, placebo-controlled, randomized clinical trial of dietary flaxseed supplementation for children and adolescents with hypercholesterolemia?. ### Response: Flaxseed in pediatric hyper -lipidemia.


Instruction: When did JAMA Pediatr. 2013 issue 167:708–13?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA Pediatr. 2013 issue 167:708–13?. ### Response: 2013.


Instruction: What is standardized lifestyle modification and benchmarking real-world practice?

Output: id-emia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is standardized lifestyle modification and benchmarking real-world practice?. ### Response: id-emia.


Instruction: What is associated with an improved lipid profile in children with familial hyper-cholesterolemia?

Output: Dietary counseling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with an improved lipid profile in children with familial hyper-cholesterolemia?. ### Response: Dietary counseling.


Instruction: What is the name of the journal that studies the relationship between diet and lipid profiles in children?

Output: JAMA Pediatr

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the relationship between diet and lipid profiles in children?. ### Response: JAMA Pediatr.


Instruction: What is hypercholesterolemia in children and adolescents?

Output: hyper -lipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hypercholesterolemia in children and adolescents?. ### Response: hyper -lipidemia.


Instruction: What is ezetimibe monotherapy in children with heterozygous chromosomes?

Output: colesevelam

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ezetimibe monotherapy in children with heterozygous chromosomes?. ### Response: colesevelam.


Instruction: What is ezetimibe monotherapy used for in children with hypercholesterolemia?

Output: improved lipid profile

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ezetimibe monotherapy used for in children with hypercholesterolemia?. ### Response: improved lipid profile.


Instruction: What is the name of the drug used in the treatment of hypercholestrolemia in children and adoles cents?

Output: colesevelam

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used in the treatment of hypercholestrolemia in children and adoles cents?. ### Response: colesevelam.


Instruction: What is ezetimibe used for in pediatric patients with hypercholesterolemia?

Output: monotherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ezetimibe used for in pediatric patients with hypercholesterolemia?. ### Response: monotherapy.


Instruction: What is the effect of colesevelam in man-aging heterozygous familial hypercholestrolemia in adolescents and children?

Output: Role

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of colesevelam in man-aging heterozygous familial hypercholestrolemia in adolescents and children?. ### Response: Role.


Instruction: What is familial hypercholesterolemia in?

Output: primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is familial hypercholesterolemia in?. ### Response: primary care.


Instruction: When did Adolesc Health Med Ther. 2010:1:53-60?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Adolesc Health Med Ther. 2010:1:53-60?. ### Response: 2010.


Instruction: What is child-parent screening for?

Output: familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is child-parent screening for?. ### Response: familial hypercholesterolemia.


Instruction: Where does Wald DS, Bestwick JP, Morris JK, et al. screen?

Output: primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does Wald DS, Bestwick JP, Morris JK, et al. screen?. ### Response: primary care.


Instruction: What type of screening is used in primary care?

Output: Child-parent familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of screening is used in primary care?. ### Response: Child-parent familial hypercholesterolemia.


Instruction: What is apolipoproteins used to screen for?

Output: familial hyper -cholesterolaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is apolipoproteins used to screen for?. ### Response: familial hyper -cholesterolaemia.


Instruction: When did the CARDIAC project begin?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the CARDIAC project begin?. ### Response: 2010.


Instruction: What is screening for familial hypercholesterolaemia by measuring apolipoproteins in capillary blood?

Output: Dietary counseling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is screening for familial hypercholesterolaemia by measuring apolipoproteins in capillary blood?. ### Response: Dietary counseling.


Instruction: What year did Arch Dis Child. 1991:66:844-7?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Arch Dis Child. 1991:66:844-7?. ### Response: 1991.


Instruction: What is the Third International Stroke Trial?

Output: a randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Third International Stroke Trial?. ### Response: a randomised controlled trial.


Instruction: How long after acute ischaemic stroke does intravenous throm-bolysis with recombinant tissue plasminogen activator occur?

Output: 6 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after acute ischaemic stroke does intravenous throm-bolysis with recombinant tissue plasminogen activator occur?. ### Response: 6 h.


Instruction: What is IST-3?

Output: Collaborative Groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is IST-3?. ### Response: Collaborative Groups.


Instruction: What is a randomised controlled trial?

Output: The benefits and harms of intravenous throm-bolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomised controlled trial?. ### Response: The benefits and harms of intravenous throm-bolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke.


Instruction: What is the name of the study that investigated the use of low-dose versus standard-dose intravenous alteplase in acute ischemic stroke?

Output: Third International Stroke Trial-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the use of low-dose versus standard-dose intravenous alteplase in acute ischemic stroke?. ### Response: Third International Stroke Trial-3.


Instruction: What is the name of the study that investigated the effect of intravenous recombinant tissue-type plasminogen ac-tivator in patients with mild stroke?

Output: Third International Stroke Trial-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effect of intravenous recombinant tissue-type plasminogen ac-tivator in patients with mild stroke?. ### Response: Third International Stroke Trial-3.


Instruction: In what year did N Engl J Med publish 374:2313–2323?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did N Engl J Med publish 374:2313–2323?. ### Response: 2016.


Instruction: What is the name of the Third International Stroke Trial-3?

Output: IST-3 Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Third International Stroke Trial-3?. ### Response: IST-3 Collaborative Group.


Instruction: What is a recombinant tissue plasminogen activator for minor stroke?

Output: National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a recombinant tissue plasminogen activator for minor stroke?. ### Response: National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience.


Instruction: What is the rt-PA Stroke Study experience?

Output: Recombinant tissue plasminogen activator for minor strokes: the National Institute of Neurological Disorders and Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rt-PA Stroke Study experience?. ### Response: Recombinant tissue plasminogen activator for minor strokes: the National Institute of Neurological Disorders and Stroke.


Instruction: What was the reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial?

Output: post hoc analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial?. ### Response: post hoc analysis.


Instruction: What is the name of the group that studies the effects of intravenous thrombolysis?

Output: IST-3 Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies the effects of intravenous thrombolysis?. ### Response: IST-3 Collaborative Group.


Instruction: What is one of the factors that affect the effect of intravenous therapy?

Output: treatment delay, age, and stroke severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the factors that affect the effect of intravenous therapy?. ### Response: treatment delay, age, and stroke severity.


Instruction: When was the last time a stroke was treated?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a stroke was treated?. ### Response: 2004.


Instruction: What are the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke?

Output: Effect of treatment delay, age, and stroke severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke?. ### Response: Effect of treatment delay, age, and stroke severity.


Instruction: What is the name of the meta-analysis of individual patient data from randomised trials?

Output: Lancet. 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of individual patient data from randomised trials?. ### Response: Lancet. 2014.


Instruction: In what year was the Lancet 384:1929-1935 published?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Lancet 384:1929-1935 published?. ### Response: 2014.


Instruction: How long after onset of acute ischaemic stroke is alteplase given?

Output: 3.0-4.5 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after onset of acute ischaemic stroke is alteplase given?. ### Response: 3.0-4.5 h.


Instruction: What is ECASS III?

Output: Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ECASS III?. ### Response: Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke.


Instruction: When was the Lancet Neurol 8:1095-1102.

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet Neurol 8:1095-1102.. ### Response: 2009.


Instruction: How long after an acute stroke is thrombolysis with alteplase 3-4.5 h?

Output: 3.0-4.5 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after an acute stroke is thrombolysis with alteplase 3-4.5 h?. ### Response: 3.0-4.5 h.


Instruction: What is the name of the SITS Investigators?

Output: Wahlgren N, Grond M, Hennerici M, Lees KR, Mikulik R, Parsons M, Roine RO, Toni D, Ringleb P

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the SITS Investigators?. ### Response: Wahlgren N, Grond M, Hennerici M, Lees KR, Mikulik R, Parsons M, Roine RO, Toni D, Ringleb P.


Instruction: When was the Lancet Neurol.9:866–874?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet Neurol.9:866–874?. ### Response: 2010.


Instruction: What type of stroke is treated with intravenous thrombolysis?

Output: mild acute ischemic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stroke is treated with intravenous thrombolysis?. ### Response: mild acute ischemic.


Instruction: What is the name of the retrospective study of stroke outcomes?

Output: Third International Stroke Trial-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the retrospective study of stroke outcomes?. ### Response: Third International Stroke Trial-3.


Instruction: What is the name of the 2019 AHA/ACC High Blood Pressure Performance and Quality MeasuresCirc Cardiovasc Qual Outcomes?

Output: Casey et al;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2019 AHA/ACC High Blood Pressure Performance and Quality MeasuresCirc Cardiovasc Qual Outcomes?. ### Response: Casey et al;.


Instruction: How many questions did Casey and colleagues answer?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many questions did Casey and colleagues answer?. ### Response: 2.


Instruction: What type of stress symptoms are there?

Output: Stress Stress symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stress symptoms are there?. ### Response: Stress Stress symptoms.


Instruction: How many questions does AUDIT-C have?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many questions does AUDIT-C have?. ### Response: 3.


Instruction: What is an example of a substance use problem?

Output: Alcohol use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a substance use problem?. ### Response: Alcohol use.


Instruction: How many questions did NHIS ask about alcohol use?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many questions did NHIS ask about alcohol use?. ### Response: 3.


Instruction: What did AUDIT-C indicate about Alcohol Use Disorders Identification?

Output: Test-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did AUDIT-C indicate about Alcohol Use Disorders Identification?. ### Response: Test-C.


Instruction: What is the acronym for Alcohol Use Disorders Identification Test-C?

Output: AUDIT-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Alcohol Use Disorders Identification Test-C?. ### Response: AUDIT-C.


Instruction: What does HARK stand for?

Output: Exposure to violence: intimate partner violence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HARK stand for?. ### Response: Exposure to violence: intimate partner violence.


Instruction: Where is the NHANES III survey located?

Output: Washington, DC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the NHANES III survey located?. ### Response: Washington, DC.


Instruction: When was the PHQ-2 survey downloaded?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the PHQ-2 survey downloaded?. ### Response: May 3, 2023.


Instruction: What is the name of the SUPPLEMENT e563STable 12—ContinuedQuality Assessment Summary of FindingsRisk of Bias Inconsistency Indirectness ImprecisionPublication BiasesStudy Event Rates (%)Relative Effect (95% CI)Estimation of Absolute Effects 1-y Time Frame?

Output: www.chestpubs.org CHEST / 141 / 2 / FEBRUARY , 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the SUPPLEMENT e563STable 12—ContinuedQuality Assessment Summary of FindingsRisk of Bias Inconsistency Indirectness ImprecisionPublication BiasesStudy Event Rates (%)Relative Effect (95% CI)Estimation of Absolute Effects 1-y Time Frame?. ### Response: www.chestpubs.org CHEST / 141 / 2 / FEBRUARY , 2012.


Instruction: What is Triple therapy with?

Output: Dual Antiplatelet Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Triple therapy with?. ### Response: Dual Antiplatelet Therapy.


Instruction: What is the 95% CI of Triple therapy?

Output: does not exclude important harm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% CI of Triple therapy?. ### Response: does not exclude important harm.


Instruction: How does Triple therapy compare to other therapies?

Output: all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Triple therapy compare to other therapies?. ### Response: all-cause mortality.


Instruction: What does PLATO 5 Study of Platelet Inhibition and Patient Outcomes do?

Output: daily medication only

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PLATO 5 Study of Platelet Inhibition and Patient Outcomes do?. ### Response: daily medication only.


Instruction: What does TIMI 5 Thrombolysis In Myocardial Infarction study?

Output: Study of Platelet Inhibition and Patient Outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does TIMI 5 Thrombolysis In Myocardial Infarction study?. ### Response: Study of Platelet Inhibition and Patient Outcomes.


Instruction: What was used to estimate the relative risk for all-cause mortality?

Output: aspirin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to estimate the relative risk for all-cause mortality?. ### Response: aspirin therapy.


Instruction: How many RCTs of patients with acute coronary syndrome were included in the study?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs of patients with acute coronary syndrome were included in the study?. ### Response: 10.


Instruction: What did the study estimate for nonfatal major extracranial bleeding?

Output: relative risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the study estimate for nonfatal major extracranial bleeding?. ### Response: relative risk.


Instruction: What did Rothberg et al 121 estimate the effect of triple therapy vs dual antiplatelet therapy on all-cause mortality in patients with AF and acute coronary syndrome?

Output: aspirin therapy vs aspirin alone in 10 RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Rothberg et al 121 estimate the effect of triple therapy vs dual antiplatelet therapy on all-cause mortality in patients with AF and acute coronary syndrome?. ### Response: aspirin therapy vs aspirin alone in 10 RCTs.


Instruction: What does the 95% CI do not exclude with triple therapy?

Output: important harm or beneﬁ  t

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the 95% CI do not exclude with triple therapy?. ### Response: important harm or beneﬁ  t.


Instruction: What did we use the same baseline estimates of for the general AF population receiving aspirin 1 clopidogrel?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we use the same baseline estimates of for the general AF population receiving aspirin 1 clopidogrel?. ### Response: mortality.


Instruction: What did Go et al report?

Output: mortality rate of 5.33 per 100 person-y in untreated (no warfarin) patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Go et al report?. ### Response: mortality rate of 5.33 per 100 person-y in untreated (no warfarin) patients.


Instruction: Who reported a mortality rate of 5.33 per 100 person-y in untreated (no warfarin) patients from an observational study?

Output: Go et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reported a mortality rate of 5.33 per 100 person-y in untreated (no warfarin) patients from an observational study?. ### Response: Go et al.


Instruction: What was the estimated relative risk of mortality with aspirin vs no therapy?

Output: 0.89

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the estimated relative risk of mortality with aspirin vs no therapy?. ### Response: 0.89.


Instruction: What is the relative risk of mortality with aspirin 1 clopidogrel?

Output: 0.98

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relative risk of mortality with aspirin 1 clopidogrel?. ### Response: 0.98.


Instruction: What is an estimated relative risk?

Output: 0.89

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an estimated relative risk?. ### Response: 0.89.


Instruction: How did we compare warfarin vs aspiricin 1 in patients with AF?

Output: relative risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did we compare warfarin vs aspiricin 1 in patients with AF?. ### Response: relative risk.


Instruction: Aspirin 1 clopidogrel in patients with AF (ACTIVE W) to estimate the relative effect of triple therapy vs dual antiplatelet therapy on nonfatal stroke and systemic embolism?

Output: underestimating the potential beneﬁ  t of triple therapy vs dual antiplatelet therapy in reducing nonfatal stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin 1 clopidogrel in patients with AF (ACTIVE W) to estimate the relative effect of triple therapy vs dual antiplatelet therapy on nonfatal stroke and systemic embolism?. ### Response: underestimating the potential beneﬁ  t of triple therapy vs dual antiplatelet therapy in reducing nonfatal stroke.


Instruction: What is the difference between triple therapy and dual antiplatelet therapy in reducing nonfatal stroke?

Output: underestimating

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between triple therapy and dual antiplatelet therapy in reducing nonfatal stroke?. ### Response: underestimating.


Instruction: What was used to estimate the annual rates of stroke (ischemic and hemorrhagic) on aspirin 1 clopidogrel?

Output: extrapolating from observed annual rates of ischemic stroke (fatal  1  nonfatal), stratiﬁ  ed by CHADS 2  score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to estimate the annual rates of stroke (ischemic and hemorrhagic) on aspirin 1 clopidogrel?. ### Response: extrapolating from observed annual rates of ischemic stroke (fatal  1  nonfatal), stratiﬁ  ed by CHADS 2  score.


Instruction: How many historical RCTs in patients with AF did Gae et al 37 conduct?

Output: six

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many historical RCTs in patients with AF did Gae et al 37 conduct?. ### Response: six.


Instruction: What is the CHADS 2 score?

Output: 141 / 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CHADS 2 score?. ### Response: 141 / 2.


Instruction: How are the estimates underlying these estimates detailed?

Output: section 1.1.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the estimates underlying these estimates detailed?. ### Response: section 1.1.4.


Instruction: What is the name of the arm of the PLATO trial of ticagrelor vs clopidogrel in patients with coronary syndrome?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the arm of the PLATO trial of ticagrelor vs clopidogrel in patients with coronary syndrome?. ### Response: clopidogrel.


Instruction: Chronic Heart Failure Treating Heart Failure  NICE 2018. All rights reserved. Subject to Notice of rights.

Output: 978 -1-4731 -3093 -7 169 6.2.5.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chronic Heart Failure Treating Heart Failure  NICE 2018. All rights reserved. Subject to Notice of rights.. ### Response: 978 -1-4731 -3093 -7 169 6.2.5.4.


Instruction: ISBN: 978-1-4731 -3093 -7 169 6.2.5.4 Economic evidence Published literature One health economic study was identified with what?

Output: the relevant comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ISBN: 978-1-4731 -3093 -7 169 6.2.5.4 Economic evidence Published literature One health economic study was identified with what?. ### Response: the relevant comparison.


Instruction: How many economic studies relating to this review question were identified but were selectively excluded?

Output: Four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many economic studies relating to this review question were identified but were selectively excluded?. ### Response: Four.


Instruction: What is the summarised health economic evidence profile below?

Output: Table 55

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the summarised health economic evidence profile below?. ### Response: Table 55.


Instruction: Why were review questions excluded?

Output: availability of more applicable evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were review questions excluded?. ### Response: availability of more applicable evidence.


Instruction: Where are the reasons for exclusion listed?

Output: Appendix  I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the reasons for exclusion listed?. ### Response: Appendix  I.


Instruction: What is in Appendix D?

Output: health economic study selection flow chart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is in Appendix D?. ### Response: health economic study selection flow chart.


Instruction: What is supraventricular tachycardia called?

Output: paroxysmal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is supraventricular tachycardia called?. ### Response: paroxysmal.


Instruction: What is atrioventricular nodal reentrant tampering?

Output: Catheter ablation of accessory path-ways

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atrioventricular nodal reentrant tampering?. ### Response: Catheter ablation of accessory path-ways.


Instruction: Who is the Atakr Multicenter Investigators Group?

Output: Calkins H, Yong P, Miller JM, et al. Catheter ablation of accessory path-ways, atrioventricular nodal reentrant tachycardia, and the atrioventricu-lar junction: final results of a prospective, multicenter clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Atakr Multicenter Investigators Group?. ### Response: Calkins H, Yong P, Miller JM, et al. Catheter ablation of accessory path-ways, atrioventricular nodal reentrant tachycardia, and the atrioventricu-lar junction: final results of a prospective, multicenter clinical trial.


Instruction: What is the name of the 1998 NASPE prospective catheter abla-tion registry?

Output: Scheinman MM, Huang S

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 1998 NASPE prospective catheter abla-tion registry?. ### Response: Scheinman MM, Huang S.


Instruction: How much does radio-frequency ablation cost?

Output: 105

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does radio-frequency ablation cost?. ### Response: 105.


Instruction: What is the name of the drug used to treat cardiac arrhythmias?

Output: Propafenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat cardiac arrhythmias?. ### Response: Propafenone.


Instruction: When was the last time a catheter was ablation used?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a catheter was ablation used?. ### Response: 1998.


Instruction: What was the date of ablation?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the date of ablation?. ### Response: 2000.


Instruction: How many complications did catheter ablation cause?

Output: 106

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many complications did catheter ablation cause?. ### Response: 106.


Instruction: What is dofetilide used for in the prevention of symptomatic episodes of paroxysmal supraventricular tachycardia?

Output: Efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is dofetilide used for in the prevention of symptomatic episodes of paroxysmal supraventricular tachycardia?. ### Response: Efficacy and safety.


Instruction: What is the name of the randomized, placebo-controlled trial of propafenone in the prophylaxis of?

Output: paroxysmal supraventricular tachycardia and paroxysmal atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, placebo-controlled trial of propafenone in the prophylaxis of?. ### Response: paroxysmal supraventricular tachycardia and paroxysmal atrial fibrillation.


Instruction: What is the name of the UK Propafenone PSVT Study Group?

Output: 92:2550–7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the UK Propafenone PSVT Study Group?. ### Response: 92:2550–7.


Instruction: What is flecainide compared to?

Output: placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is flecainide compared to?. ### Response: placebo.


Instruction: Who was the author of the report?

Output: Flecainide and Propafenone Italian Study (FAPIS) Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of the report?. ### Response: Flecainide and Propafenone Italian Study (FAPIS) Group.


Instruction: Where did the FAPIS Group come from?

Output: Flecainide and Propafenone Italian Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did the FAPIS Group come from?. ### Response: Flecainide and Propafenone Italian Study.


Instruction: What is the name of the study group that treats paroxysmal supraventricular tachyarrhythmias?

Output: Multicenter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that treats paroxysmal supraventricular tachyarrhythmias?. ### Response: Multicenter.


Instruction: What is another name for the Flecainide Supraventricular Tachycardia Study Group?

Output: VT Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the Flecainide Supraventricular Tachycardia Study Group?. ### Response: VT Study Group.


Instruction: Flecainide acetate treatment of what two conditions?

Output: paroxysmal supraventricular tachycardia and paroxysmal atrial fibrilla-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Flecainide acetate treatment of what two conditions?. ### Response: paroxysmal supraventricular tachycardia and paroxysmal atrial fibrilla-tion.


Instruction: What is the name of the study group that studied the treatment of paroxysmal supraventricular tachycardia and atrial fibrilla-tion?

Output: UK Propafenone PSVT Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studied the treatment of paroxysmal supraventricular tachycardia and atrial fibrilla-tion?. ### Response: UK Propafenone PSVT Study Group.


Instruction: When was the J Am Coll Cardiol 17:297-303 published?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 17:297-303 published?. ### Response: 1991.


Instruction: Propafenone treatment in patients tolerating oral therapy?

Output: 113

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Propafenone treatment in patients tolerating oral therapy?. ### Response: 113.


Instruction: What is a crossover trial in patients tolerating oral therapy?

Output: Propafenone treatment of symptomatic paroxysmal supraventricular arrhythmias. A randomized, placebo-controlled

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a crossover trial in patients tolerating oral therapy?. ### Response: Propafenone treatment of symptomatic paroxysmal supraventricular arrhythmias. A randomized, placebo-controlled.


Instruction: What is Mortality and morbid-ity in patients receiving encainide?

Output: placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Mortality and morbid-ity in patients receiving encainide?. ### Response: placebo.


Instruction: How many patients were enrolled in the Cardiac Arrhythmia Suppression Trial?

Output: 114

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the Cardiac Arrhythmia Suppression Trial?. ### Response: 114.


Instruction: What is sotalol used for in the prophylactic treatment of pa-tients with paroxysmal supraventricular tachyarrhythmias?

Output: Multicenter comparative study of the efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is sotalol used for in the prophylactic treatment of pa-tients with paroxysmal supraventricular tachyarrhythmias?. ### Response: Multicenter comparative study of the efficacy and safety.


Instruction: What is the name of the 1997 study that compares the efficacy and safety of the drug?

Output: Multicenter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 1997 study that compares the efficacy and safety of the drug?. ### Response: Multicenter.


Instruction: What is the name of the study that compares single-dose intravenous and long-term oral doses?

Output: Multicenter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares single-dose intravenous and long-term oral doses?. ### Response: Multicenter.


Instruction: What does M, et al. compare?

Output: propafenone and placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does M, et al. compare?. ### Response: propafenone and placebo.


Instruction: What year did the United States have more Stroke than carotid endarterectomy?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the United States have more Stroke than carotid endarterectomy?. ### Response: 2005.


Instruction: What is the cost-effectiveness analysis of carotide artery stenting compared with?

Output: endarterectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness analysis of carotide artery stenting compared with?. ### Response: endarterectomy.


Instruction: How many strokes were there in the US in 2005?

Output: 3822

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in the US in 2005?. ### Response: 3822.


Instruction: What is the name of the group that recommends screening for carotid artery stenosis?

Output: U.S. Preventive Services Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that recommends screening for carotid artery stenosis?. ### Response: U.S. Preventive Services Task Force.


Instruction: When was Stroke Cerebrovasc Dis published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Stroke Cerebrovasc Dis published?. ### Response: 2010.


Instruction: What is CREST-2: Guiding treatments for?

Output: asymp-tomatic carotid disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CREST-2: Guiding treatments for?. ### Response: asymp-tomatic carotid disease.


Instruction: What is now best for pre-vention of stroke associated with asymptomatic severe carotid stenosis?

Output: Medical (nonsurgical) intervention alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is now best for pre-vention of stroke associated with asymptomatic severe carotid stenosis?. ### Response: Medical (nonsurgical) intervention alone.


Instruction: What is the risk of ipsi-lateral stroke in patients with stroke?

Output: Low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of ipsi-lateral stroke in patients with stroke?. ### Response: Low.


Instruction: What is the risk of ipsi-lateral stroke in patients with asymptomatic carotid stenosis?

Output: Low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of ipsi-lateral stroke in patients with asymptomatic carotid stenosis?. ### Response: Low.


Instruction: What is a prospective, population-based study?

Output: Low risk of ipsi-lateral stroke in patients with asymptomatic carotid stenosis on best medical treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prospective, population-based study?. ### Response: Low risk of ipsi-lateral stroke in patients with asymptomatic carotid stenosis on best medical treatment.


Instruction: How many people were enrolled in the 2010 Stroke.41:e11-e17?

Output: 543

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the 2010 Stroke.41:e11-e17?. ### Response: 543.


Instruction: What is the acronym for the Asymptomatic Carotid Surgery Trial?

Output: Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Asymptomatic Carotid Surgery Trial?. ### Response: Collaborative Group.


Instruction: How long does it take to prevent stroke?

Output: 10-Year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to prevent stroke?. ### Response: 10-Year.


Instruction: What type of endarterectomy for asymptomatic stenosis is called?

Output: carotid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of endarterectomy for asymptomatic stenosis is called?. ### Response: carotid.


Instruction: What is the name of the multicentre randomised trial of stroke prevention?

Output: Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicentre randomised trial of stroke prevention?. ### Response: Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group.


Instruction: What is ASC-1?

Output: 10-Year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ASC-1?. ### Response: 10-Year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial.


Instruction: How many people were involved in the ASC-1 trial?

Output: 548

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were involved in the ASC-1 trial?. ### Response: 548.


Instruction: What is the cause of asymp-tomatic carotid stenosis?

Output: ipsi-lateral stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of asymp-tomatic carotid stenosis?. ### Response: ipsi-lateral stroke.


Instruction: How many neurological events are there?

Output: ipsilateral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many neurological events are there?. ### Response: ipsilateral.


Instruction: What was the title of Adams RJ's ed. on Sickle Cell Disease?

Output: Basic Principals and Clinical Practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of Adams RJ's ed. on Sickle Cell Disease?. ### Response: Basic Principals and Clinical Practice.


Instruction: What is the name of the committee that studies brain magnetic resonance imaging in children with sickle cell disease?

Output: Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that studies brain magnetic resonance imaging in children with sickle cell disease?. ### Response: Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease.


Instruction: When was the last issue of Pediatrics published?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of Pediatrics published?. ### Response: 1996.


Instruction: What is the name of the disease that causes cerebrovascular accidents in sickle cell disease?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes cerebrovascular accidents in sickle cell disease?. ### Response: stroke.


Instruction: What are the rates and risk factors for?

Output: Cerebrovascular accidents in sickle cell disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the rates and risk factors for?. ### Response: Cerebrovascular accidents in sickle cell disease.


Instruction: When did Blood. 1998:91:288-294?

Output: 550

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Blood. 1998:91:288-294?. ### Response: 550.


Instruction: What is the use of transcranial ultrasonography to predict stroke in sickle cell disease?

Output: 551

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use of transcranial ultrasonography to predict stroke in sickle cell disease?. ### Response: 551.


Instruction: What was the N Engl J Med. 1992;326:605-601.

Output: Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med. 1992;326:605-601.. ### Response: Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group.


Instruction: What did Adams RJ, McKie VC, Carl EM, Nichols FT, Perry R, Brock K, Mckie K do?

Output: cost-effective-ness analysis of carotid artery stenting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Adams RJ, McKie VC, Carl EM, Nichols FT, Perry R, Brock K, Mckie K do?. ### Response: cost-effective-ness analysis of carotid artery stenting.


Instruction: On Clinical Practice Guidelines University of Texas MD Anderson Cancer Center—Department Chair, Cardiology, Ting Tsung and Wei Fong Chao Distinguished Chair, Professor of Medicine

Output: None None None •  NIH* •  ACC•  AHA•  Heart Failure Society of America†NoneAnn Bolger Content Reviewer—ACC/AHA University of California, San Francisco-Professor of Medicine•  General Electric None None None None None(Continued )Downloaded from http://ahajournals.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On Clinical Practice Guidelines University of Texas MD Anderson Cancer Center—Department Chair, Cardiology, Ting Tsung and Wei Fong Chao Distinguished Chair, Professor of Medicine. ### Response: None None None •  NIH* •  ACC•  AHA•  Heart Failure Society of America†NoneAnn Bolger Content Reviewer—ACC/AHA University of California, San Francisco-Professor of Medicine•  General Electric None None None None None(Continued )Downloaded from http://ahajournals..


Instruction: What is the name of the University of California, San Francisco-Professor of Medicine?

Output: Ann Bolger

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the University of California, San Francisco-Professor of Medicine?. ### Response: Ann Bolger.


Instruction: Who is the Content Reviewer for AmericaNoneAnn Bolger?

Output: General Electric

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Content Reviewer for AmericaNoneAnn Bolger?. ### Response: General Electric.


Instruction: When was this content downloaded?

Output: April 27, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this content downloaded?. ### Response: April 27, 2023.


Instruction: What type of stroke did Taiwanese with nonvalvular atrial fibrillation have?

Output: ischemic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stroke did Taiwanese with nonvalvular atrial fibrillation have?. ### Response: ischemic.


Instruction: What is the name of the systematic review of atherosclerosis published in 2011?

Output: Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of atherosclerosis published in 2011?. ### Response: Atherosclerosis.


Instruction: How many patients were enrolled in a nationwide cohort study in 2014?

Output: 299

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in a nationwide cohort study in 2014?. ### Response: 299.


Instruction: What is the name of the meta-analysis of randomizedcontrolled trials of non-vitamin K antagonistoral anticoagulants and antiplatelet therapy for stroke prevention inpatients with atrial fibrillation?

Output: a meta-analysis of randomizedcontrolled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of randomizedcontrolled trials of non-vitamin K antagonistoral anticoagulants and antiplatelet therapy for stroke prevention inpatients with atrial fibrillation?. ### Response: a meta-analysis of randomizedcontrolled trials.


Instruction: What does Circulation.2014;129(15):1577-1585?

Output: .294

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Circulation.2014;129(15):1577-1585?. ### Response: .294.


Instruction: What is the name of the RandomizedEvaluation of Long-Term Anticoagulation Therapy trial?

Output: RE-LY

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the RandomizedEvaluation of Long-Term Anticoagulation Therapy trial?. ### Response: RE-LY.


Instruction: What does RE-LY stand for?

Output: RandomizedEvaluation of Long-Term Anticoagulation Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does RE-LY stand for?. ### Response: RandomizedEvaluation of Long-Term Anticoagulation Therapy.


Instruction: How isrivaroxaban compared to warfarin in patients with peripheral arterial disease?

Output: Ef ﬁcacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How isrivaroxaban compared to warfarin in patients with peripheral arterial disease?. ### Response: Ef ﬁcacy and safety.


Instruction: What type of atrial fibrillation can be treated with catheter and surgical ablation?

Output: non-valvular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of atrial fibrillation can be treated with catheter and surgical ablation?. ### Response: non-valvular.


Instruction: What is the name of the expert consensus statement issued by HRS/EHRA/ECAS/APHRS/SOLAECE?

Output: Calkins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the expert consensus statement issued by HRS/EHRA/ECAS/APHRS/SOLAECE?. ### Response: Calkins.


Instruction: How many pages are in Europace in 2018?

Output: e1-e160 .298

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages are in Europace in 2018?. ### Response: e1-e160 .298.


Instruction: What is the name of the randomized trial of Coumadin in PreventingThromboembolism in Atrial Fibrillation (AF) Patients UndergoingCatheter Ablation?

Output: COMPARE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of Coumadin in PreventingThromboembolism in Atrial Fibrillation (AF) Patients UndergoingCatheter Ablation?. ### Response: COMPARE.


Instruction: What is the name of the randomized trial?

Output: COMPARE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial?. ### Response: COMPARE.


Instruction: What is uninterrupteddrivaroxaban vs. uninterrupted vitamin K antagonists for?

Output: catheterablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uninterrupteddrivaroxaban vs. uninterrupted vitamin K antagonists for?. ### Response: catheterablation.


Instruction: Uninterrupteddabigatran versus warfarin for ablation in atrial fibrillation?

Output: Calkins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Uninterrupteddabigatran versus warfarin for ablation in atrial fibrillation?. ### Response: Calkins.


Instruction: What is the BRUISE CONTROL-2 trial?

Output: Strategy of continuedvs interrupted novel oral anticoagulant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BRUISE CONTROL-2 trial?. ### Response: Strategy of continuedvs interrupted novel oral anticoagulant.


Instruction: What is the name of the BRUISE CONTROL-2 trial?

Output: Essebag V, Healey JS, Ayala-Paredes F, et al. Strategy of continuedvs interrupted novel oral anticoagulant at time of device surgery inpatients with moderate to high risk of arterial thromboembolicevents: the BRUISE CONTROL-2 trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the BRUISE CONTROL-2 trial?. ### Response: Essebag V, Healey JS, Ayala-Paredes F, et al. Strategy of continuedvs interrupted novel oral anticoagulant at time of device surgery inpatients with moderate to high risk of arterial thromboembolicevents: the BRUISE CONTROL-2 trial.


Instruction: What is evidence-based medicine?

Output: Am Heart J . 2016;173:102-107.1196

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evidence-based medicine?. ### Response: Am Heart J . 2016;173:102-107.1196.


Instruction: What should be considered for unstable patients with a suspected cardiac etiology regardless of whether the patient is comatose or not?

Output: S6-7 and emergency coronary angiogra-phy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered for unstable patients with a suspected cardiac etiology regardless of whether the patient is comatose or not?. ### Response: S6-7 and emergency coronary angiogra-phy.


Instruction: What is suspected regardless of whether the patient is comatose or awake?

Output: cardiac etiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is suspected regardless of whether the patient is comatose or awake?. ### Response: cardiac etiology.


Instruction: In 1 observational study of patients resuscitated from SCA who did not have ST elevation and had angiography, how many were found to have a cul-prit lesion?

Output: one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 1 observational study of patients resuscitated from SCA who did not have ST elevation and had angiography, how many were found to have a cul-prit lesion?. ### Response: one third.


Instruction: What appeared to be associated with a greater likelihood of coronary intervention?

Output: hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What appeared to be associated with a greater likelihood of coronary intervention?. ### Response: hypotension.


Instruction: What type of intervention appeared to be associated with a greater likelihood of favorable neurologic outcome?

Output: coronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention appeared to be associated with a greater likelihood of favorable neurologic outcome?. ### Response: coronary.


Instruction: What should be performed for hemody-namic instability at presentation or if it develops subsequently?

Output: Immediate cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed for hemody-namic instability at presentation or if it develops subsequently?. ### Response: Immediate cardioversion.


Instruction: What should be obtained for sta-ble rhythms?

Output: An ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be obtained for sta-ble rhythms?. ### Response: An ECG.


Instruction: What can be due to VT, SVT with aberrancy, preexcited tachycardia, or a paced rhythm?

Output: Wide-complex tachycardias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be due to VT, SVT with aberrancy, preexcited tachycardia, or a paced rhythm?. ### Response: Wide-complex tachycardias.


Instruction: What is an irregular wide-complex tachycar -dia?

Output: AF with aberrancy, preexcited AF (ie, AF using an accessory pathway for anterograde conduction), atrial flutter, or VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an irregular wide-complex tachycar -dia?. ### Response: AF with aberrancy, preexcited AF (ie, AF using an accessory pathway for anterograde conduction), atrial flutter, or VT.


Instruction: What is AF with aberrancy, preexcited AF, atrial flutter, or VT?

Output: An irregular wide-complex tachycar -dia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AF with aberrancy, preexcited AF, atrial flutter, or VT?. ### Response: An irregular wide-complex tachycar -dia.


Instruction: A diagnosis should be established and what should be considered?

Output: consultation with an arrhythmia expert

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A diagnosis should be established and what should be considered?. ### Response: consultation with an arrhythmia expert.


Instruction: Which drug was more effective in terminating incessant VT than lidocaine in 1 study?

Output: amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug was more effective in terminating incessant VT than lidocaine in 1 study?. ### Response: amiodarone.


Instruction: How long did amiodarone have an improved survival?

Output: 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did amiodarone have an improved survival?. ### Response: 24 hours.


Instruction: Which drug has been shown to be superior for terminating arrhythmia in patients with recurrent, stable VT not in the setting of an AMI?

Output: procainamide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug has been shown to be superior for terminating arrhythmia in patients with recurrent, stable VT not in the setting of an AMI?. ### Response: procainamide.


Instruction: What is lidocaine used for?

Output: antiar -rhythmic medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lidocaine used for?. ### Response: antiar -rhythmic medication.


Instruction: How many patients in a randomized trial found procainamide superior to amio-darone for termination of stable VT?

Output: 62

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients in a randomized trial found procainamide superior to amio-darone for termination of stable VT?. ### Response: 62.


Instruction: Adverse events, including hypotension, were more common with what drug?

Output: amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adverse events, including hypotension, were more common with what drug?. ### Response: amiodarone.


Instruction: What is n-acetylprocainamide's metabolite called?

Output: Procainamide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is n-acetylprocainamide's metabolite called?. ### Response: Procainamide.


Instruction: What is the name of the alternative antiar-rhythmic medication of longstanding and widespread familiarity?

Output: Intravenous lidocaine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the alternative antiar-rhythmic medication of longstanding and widespread familiarity?. ### Response: Intravenous lidocaine.


Instruction: What did lidocaine not consistently increase after defibrillation?

Output: a return of spontaneous circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did lidocaine not consistently increase after defibrillation?. ### Response: a return of spontaneous circulation.


Instruction: What was not asso-ciated with improvement in survival to hospital discharge?

Output: lidocaine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not asso-ciated with improvement in survival to hospital discharge?. ### Response: lidocaine.


Instruction: In prospective, blinded, RCTs, what was less effective than amiodarone in improving hospital survival?

Output: lidocaine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In prospective, blinded, RCTs, what was less effective than amiodarone in improving hospital survival?. ### Response: lidocaine.


Instruction: What was less effective than amiodarone in improving hospital admission rates?

Output: lidocaine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was less effective than amiodarone in improving hospital admission rates?. ### Response: lidocaine.


Instruction: What did lidocaine improve after out-of-hospital cardiac arrest?

Output: hospital admission rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did lidocaine improve after out-of-hospital cardiac arrest?. ### Response: hospital admission rates.


Instruction: What year did 2050 Stroke strike?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did 2050 Stroke strike?. ### Response: 2015.


Instruction: What is the name of the group member who was a Stroker in 2015?

Output: Employment Research GrantOther Research SupportSpeakers’ Bureau/ HonorariaExpert WitnessOwnership InterestConsultant/ Advisory Board OtherJ. Claude Hemphill III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group member who was a Stroker in 2015?. ### Response: Employment Research GrantOther Research SupportSpeakers’ Bureau/ HonorariaExpert WitnessOwnership InterestConsultant/ Advisory Board OtherJ. Claude Hemphill III.


Instruction: Who is a Speakers’ Bureau/ Honoraria?

Output: Expert Witness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Speakers’ Bureau/ Honoraria?. ### Response: Expert Witness.


Instruction: What is the name of the NIH?

Output: NIH/NHLBI†

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the NIH?. ### Response: NIH/NHLBI†.


Instruction: Where is the George Institute for Global Health located?

Output: University of Sydney

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the George Institute for Global Health located?. ### Response: University of Sydney.


Instruction: Who is the NHMRC of Australia?

Output: National Health and Medical Research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the NHMRC of Australia?. ### Response: National Health and Medical Research.


Instruction: What University of Washington School of Medicine is a non-profit organization?

Output: Kyra Becker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What University of Washington School of Medicine is a non-profit organization?. ### Response: Kyra Becker.


Instruction: What is the name of the foundation that founded the Northwestern Medical Faculty Foundation?

Output: Bernard R. Bendok

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the foundation that founded the Northwestern Medical Faculty Foundation?. ### Response: Bernard R. Bendok.


Instruction: Which University of Vermont is an NIH/NHLBI entity?

Output: Mary Cushman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which University of Vermont is an NIH/NHLBI entity?. ### Response: Mary Cushman.


Instruction: What is the name of the Massachusetts General Hospital?

Output: Joshua N. Goldstein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Massachusetts General Hospital?. ### Response: Joshua N. Goldstein.


Instruction: Who is the founder of the Brain Aneurysm Foundation?

Output: R. Loch Macdonald

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the founder of the Brain Aneurysm Foundation?. ### Response: R. Loch Macdonald.


Instruction: What is Edge Therapeutics?

Output: Actelion Pharmaceuticals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Edge Therapeutics?. ### Response: Actelion Pharmaceuticals.


Instruction: What is Philip A. Scott University of Michigan NIH/NINDS?

Output: None None None None None NoneMag

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Philip A. Scott University of Michigan NIH/NINDS?. ### Response: None None None None None NoneMag.


Instruction: Who is a Harvard Medical Faculty Physician?

Output: Magdy H. Selim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Harvard Medical Faculty Physician?. ### Response: Magdy H. Selim.


Instruction: What is the name of the Harvard Medical Faculty Physicians?

Output: Magdy H. Selim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Harvard Medical Faculty Physicians?. ### Response: Magdy H. Selim.


Instruction: What type of conflicts of interest are reported on the Disclosure Questionnaire?

Output: actual or reasonably perceived

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of conflicts of interest are reported on the Disclosure Questionnaire?. ### Response: actual or reasonably perceived.


Instruction: Who is a member of the Writing Group?

Output: Employment Research Grant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the Writing Group?. ### Response: Employment Research Grant.


Instruction: What is required of all members of the writing group to complete and submit?

Output: Disclosure Questionnaire

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required of all members of the writing group to complete and submit?. ### Response: Disclosure Questionnaire.


Instruction: What is a relationship considered to be if the person receives $10 000 or more during a 12-month period?

Output: significant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if the person receives $10 000 or more during a 12-month period?. ### Response: significant.


Instruction: What percentage of a person's gross income does the person own?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of a person's gross income does the person own?. ### Response: 5%.


Instruction: How much of the fair market value of an entity is the relationship considered to be?

Output: $10 000 or more

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the fair market value of an entity is the relationship considered to be?. ### Response: $10 000 or more.


Instruction: What is a relationship considered if it is moderate?

Output: less than “significant”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered if it is moderate?. ### Response: less than “significant”.


Instruction: What is a relationship considered to be if it is less than "significant"?

Output: modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if it is less than "significant"?. ### Response: modest.


Instruction: What is the result of improved hospital care?

Output: DisclosuresICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the result of improved hospital care?. ### Response: DisclosuresICH.


Instruction: Improvements in hospital care tend to be incremental rather than what?

Output: revolutionary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Improvements in hospital care tend to be incremental rather than what?. ### Response: revolutionary.


Instruction: What is a key part of future ICH research?

Output: Improvements in hospital care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key part of future ICH research?. ### Response: Improvements in hospital care.


Instruction: What is limited in its ability to reduce stroke-related disability?

Output: Acute ICH treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is limited in its ability to reduce stroke-related disability?. ### Response: Acute ICH treatment.


Instruction: What is NICE 2018?

Output: All rights reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: All rights reserved.


Instruction: What is the name of the study that NICE is focusing on?

Output: Atienza

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that NICE is focusing on?. ### Response: Atienza.


Instruction: Who is the author of NICE?

Output: 978 -1-4731 -3093 -7 348

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of NICE?. ### Response: 978 -1-4731 -3093 -7 348.


Instruction: How long does it take to follow up a patient?

Output: 2 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to follow up a patient?. ### Response: 2 year.


Instruction: What is QALY?

Output: quality -adjusted life years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is QALY?. ### Response: quality -adjusted life years.


Instruction: How many nurses are involved in a geriatrics case manager?

Output: two to four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many nurses are involved in a geriatrics case manager?. ### Response: two to four.


Instruction: What may not reflect current NHS context?

Output: Spanish resource use data and unit costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not reflect current NHS context?. ### Response: Spanish resource use data and unit costs.


Instruction: What is not used as the health outcome measure?

Output: QALYs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not used as the health outcome measure?. ### Response: QALYs.


Instruction: Atienza is 1 of how many studies included comparing MDT clinic to usual care in high risk patients?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atienza is 1 of how many studies included comparing MDT clinic to usual care in high risk patients?. ### Response: 5.


Instruction: No exploration of what?

Output: uncertainty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No exploration of what?. ### Response: uncertainty.


Instruction: What may Italian national health service resource use and unit costs may be?

Output: not

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may Italian national health service resource use and unit costs may be?. ### Response: not.


Instruction: What may not reflect current UK NHS context?

Output: Italian national health service resource use and unit costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not reflect current UK NHS context?. ### Response: Italian national health service resource use and unit costs.


Instruction: What was not reported clearly enough to report and therefore were not used as the health outcome measure?

Output: QAL Y data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not reported clearly enough to report and therefore were not used as the health outcome measure?. ### Response: QAL Y data.


Instruction: What is 1 of 5 studies included comparing MDT clinic to usual care in high risk patients?

Output: Pulignan o

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 1 of 5 studies included comparing MDT clinic to usual care in high risk patients?. ### Response: Pulignan o.


Instruction: What does not reflect the full body of evidence available for this comparison?

Output: Within -trial analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not reflect the full body of evidence available for this comparison?. ### Response: Within -trial analysis.


Instruction: What is the difference between home -based MDT and n urse led MDT clinic?

Output: long  intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between home -based MDT and n urse led MDT clinic?. ### Response: long  intervention.


Instruction: What are the differences between home-based and snurse-led MDT?

Output: long  intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between home-based and snurse-led MDT?. ### Response: long  intervention.


Instruction: In high risk patients, what is the main difference between Home -Based MDT vs. usual care?

Output: No exploration of uncertainty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In high risk patients, what is the main difference between Home -Based MDT vs. usual care?. ### Response: No exploration of uncertainty.


Instruction: What are the limitations of a Cost -utility analysis?

Output: Potentially serious limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the limitations of a Cost -utility analysis?. ### Response: Potentially serious limitations.


Instruction: What is the population of patients >18 years old?

Output: structural cardiac dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population of patients >18 years old?. ### Response: structural cardiac dysfunction.


Instruction: How old are the patients with structural cardiac dysfunction?

Output: >18 years old

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are the patients with structural cardiac dysfunction?. ### Response: >18 years old.


Instruction: What is the population of the patients?

Output: >18 years old

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population of the patients?. ### Response: >18 years old.


Instruction: How much is the cost saving of the intervention?

Output: £58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much is the cost saving of the intervention?. ### Response: £58.


Instruction: What dominates 1 and 3 (more effective and less costly)?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What dominates 1 and 3 (more effective and less costly)?. ### Response: 2.


Instruction: What is the threshold for Probability intervention 2 cost-effective?

Output: 62%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the threshold for Probability intervention 2 cost-effective?. ### Response: 62%.


Instruction: What was the proportion of ischemic strokes undergoing computed tomographic angiography between 2006 and 2010?

Output: 9.1%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the proportion of ischemic strokes undergoing computed tomographic angiography between 2006 and 2010?. ### Response: 9.1%.


Instruction: What did CTA increase from 0.05% to 2.9%?

Output: Computed tomography perfusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did CTA increase from 0.05% to 2.9%?. ### Response: Computed tomography perfusion.


Instruction: What was more common among those who were imaged with CTA and CTP?

Output: Reperfusion treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was more common among those who were imaged with CTA and CTP?. ### Response: Reperfusion treatment.


Instruction: What percentage of patients received reperfusion treatment?

Output: 13.0%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients received reperfusion treatment?. ### Response: 13.0%).


Instruction: How much of a difference was there between CT and CTA?

Output: 13.0%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of a difference was there between CT and CTA?. ### Response: 13.0%).


Instruction: What should be taken into account for imaging at small or remote-access hospitals?

Output: resource availability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be taken into account for imaging at small or remote-access hospitals?. ### Response: resource availability.


Instruction: What should realistic expectations for gains in efficiency take into account?

Output: resource availability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should realistic expectations for gains in efficiency take into account?. ### Response: resource availability.


Instruction: When is Telemedicine (Continued) COR LOE New, Revised, or Unchanged?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is Telemedicine (Continued) COR LOE New, Revised, or Unchanged?. ### Response: April 28, 2023.


Instruction: Chronic Heart Failure Treating Heart Failure  NICE 2018. All rights reserved. Subject to Notice of rights.

Output: 978 -1-4731 -3093 -7 185

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chronic Heart Failure Treating Heart Failure  NICE 2018. All rights reserved. Subject to Notice of rights.. ### Response: 978 -1-4731 -3093 -7 185.


Instruction: What is the ISBN number of the study intervention and comparison Population Outcomes per day according to response?

Output: 978 -1-4731 -3093 -7 185

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ISBN number of the study intervention and comparison Population Outcomes per day according to response?. ### Response: 978 -1-4731 -3093 -7 185.


Instruction: What was the duration of Placebo?

Output: 3 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the duration of Placebo?. ### Response: 3 years.


Instruction: What type of diuretic was used?

Output: loop

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diuretic was used?. ### Response: loop.


Instruction: How long did the HF last?

Output: 6 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the HF last?. ### Response: 6 weeks.


Instruction: What is the most common LVEF 35% CKD subgroup?

Output: eGFR~26a-59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common LVEF 35% CKD subgroup?. ### Response: eGFR~26a-59.


Instruction: What type of trial was Voors 2014361?

Output: SHIFT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of trial was Voors 2014361?. ### Response: SHIFT.


Instruction: How many patients with CKD were in the SHIFT trial?

Output: 1579

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with CKD were in the SHIFT trial?. ### Response: 1579.


Instruction: What was the target dose of Ivabradine?

Output: 7·5 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the target dose of Ivabradine?. ### Response: 7·5 mg.


Instruction: How long was the median duration of the Placebo?

Output: 23 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the median duration of the Placebo?. ### Response: 23 months.


Instruction: N=1579 patients with CKD Pre-specified subgroup of what?

Output: multicentre trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: N=1579 patients with CKD Pre-specified subgroup of what?. ### Response: multicentre trial.


Instruction: Adults in sinus rhythm 70 bpm.

Output: 978 -1-4731 -3093 -7 185

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults in sinus rhythm 70 bpm.. ### Response: 978 -1-4731 -3093 -7 185.


Instruction: Stable symptomatic heart failure, admission for HF within the previous year, and an LVEF of 35% what subgroup?

Output: CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stable symptomatic heart failure, admission for HF within the previous year, and an LVEF of 35% what subgroup?. ### Response: CKD.


Instruction: What percentage of patients in the trial had CKD stage 3a+?

Output: 26%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in the trial had CKD stage 3a+?. ### Response: 26%.


Instruction: What type of trial was funded by industry?

Output: SHIFT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of trial was funded by industry?. ### Response: SHIFT.


Instruction: What was the name of the DIG trial?

Output: Shlipak 2004311

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the DIG trial?. ### Response: Shlipak 2004311.


Instruction: How many patients with CKD had a placebo duration?

Output: 3 years  N=3157

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with CKD had a placebo duration?. ### Response: 3 years  N=3157.


Instruction: How long did the duration mean?

Output: 3 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the duration mean?. ### Response: 3 years.


Instruction: How many patients with CKD were in the multicentre North American trial?

Output: 46%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with CKD were in the multicentre North American trial?. ### Response: 46%.


Instruction: What was the eGFR 30 -59, stage 3 subgroup?

Output: CKD subgroup

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the eGFR 30 -59, stage 3 subgroup?. ### Response: CKD subgroup.


Instruction: What percentage of patients in the trial had CKD?

Output: 46%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in the trial had CKD?. ### Response: 46%.


Instruction: What was the eGFR 30 -59, stage 3?

Output: n=2939

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the eGFR 30 -59, stage 3?. ### Response: n=2939.


Instruction: How many strata were there?

Output: Two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strata were there?. ### Response: Two.


Instruction: Ejection fraction: All reduced NYHA class: Mixed?

Output: Mixed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ejection fraction: All reduced NYHA class: Mixed?. ### Response: Mixed.


Instruction: What is the name of the WARCEF Investigators?

Output: Lip GY , Di Tullio MR, Sanford AR, Mejia V , Gabriel AP, del Valle ML, Buchsbaum R

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the WARCEF Investigators?. ### Response: Lip GY , Di Tullio MR, Sanford AR, Mejia V , Gabriel AP, del Valle ML, Buchsbaum R.


Instruction: What does Warfarin and aspirin do in patients with heart failure and sinus rhythm?

Output: WARCEF Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Warfarin and aspirin do in patients with heart failure and sinus rhythm?. ### Response: WARCEF Investigators.


Instruction: When did N Engl J Med issue 366:1859–1869.

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 366:1859–1869.. ### Response: 2012.


Instruction: What was the impact of warfarin on heart failure?

Output: Prevention of disabling and fatal strokes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the impact of warfarin on heart failure?. ### Response: Prevention of disabling and fatal strokes.


Instruction: What is the impact of cardiovascular disease prevalence on women's enrollment in landmark randomized cardiovascular trials?

Output: a systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of cardiovascular disease prevalence on women's enrollment in landmark randomized cardiovascular trials?. ### Response: a systematic review.


Instruction: What is a benefit of carotid endarterectomy in symptomatic patients with high-grade carotide stenosis?

Output: Beneficial effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a benefit of carotid endarterectomy in symptomatic patients with high-grade carotide stenosis?. ### Response: Beneficial effect.


Instruction: What type of endarterectomy in symptomatic patients with high-grade carotid stenosis?

Output: carotid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of endarterectomy in symptomatic patients with high-grade carotid stenosis?. ### Response: carotid.


Instruction: What is the N Engl J Med. 1993;325:445–453.

Output: randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 1993;325:445–453.. ### Response: randomised controlled trial.


Instruction: What is the MRC European Carotid Surgery Trial (ECST) called?

Output: Randomised trial of endarterectomy for recently symptomatic carotid stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MRC European Carotid Surgery Trial (ECST) called?. ### Response: Randomised trial of endarterectomy for recently symptomatic carotid stenosis.


Instruction: When did the ECST endarterectomy trial conclude?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the ECST endarterectomy trial conclude?. ### Response: 1998.


Instruction: What type of stenosis is symptomatic?

Output: moderate or severe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stenosis is symptomatic?. ### Response: moderate or severe.