Instruction: How long was the follow-up of the mitral commisurotomies?

Output: 20 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the follow-up of the mitral commisurotomies?. ### Response: 20 years.


Instruction: What was the outcome of the five-year follow up?

Output: Comparison of open commissurotomy and balloon valvuloplasty in mitral stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the five-year follow up?. ### Response: Comparison of open commissurotomy and balloon valvuloplasty in mitral stenosis.


Instruction: What is the difference between percutaneous mitral balloon valvuloplasty and open cardiac surgery?

Output: Long-term outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between percutaneous mitral balloon valvuloplasty and open cardiac surgery?. ### Response: Long-term outcomes.


Instruction: What is a randomized comparative study of bal-loon and closed mitral valvotomy?

Output: Immediate and long-term results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomized comparative study of bal-loon and closed mitral valvotomy?. ### Response: Immediate and long-term results.


Instruction: What is the difference between surgical closed mitral valvotomy and open mitral valveotomy?

Output: Immediate and long-term results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between surgical closed mitral valvotomy and open mitral valveotomy?. ### Response: Immediate and long-term results.


Instruction: What is a randomized comparative study?

Output: Percutaneous mitral commissur -otomy versus open mitral commissurotomy: a comparative study. Eur J Cardiothorac Surg. 1999;15:646–51. 7. Song J-K, Kim M-J, Yun S-C, et al. Long-term outcomes of percutaneous mitral balloon valvuloplasty versus open cardiac surgery. J Thorac Cardio-vasc Surg. 2010;139:103–10. 8. Arora R, Nair M, Kalra GS, et al. Immediate and long-term results of bal-loon and surgical closed mitral valvotomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomized comparative study?. ### Response: Percutaneous mitral commissur -otomy versus open mitral commissurotomy: a comparative study. Eur J Cardiothorac Surg. 1999;15:646–51. 7. Song J-K, Kim M-J, Yun S-C, et al. Long-term outcomes of percutaneous mitral balloon valvuloplasty versus open cardiac surgery. J Thorac Cardio-vasc Surg. 2010;139:103–10. 8. Arora R, Nair M, Kalra GS, et al. Immediate and long-term results of bal-loon and surgical closed mitral valvotomy.


Instruction: What type of valve is usually required because of the potential for LVOT obstruction from the struts?

Output: mechanical valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve is usually required because of the potential for LVOT obstruction from the struts?. ### Response: mechanical valve.


Instruction: What is the name of the 2018 ACHD Guideline?

Output: Stout et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2018 ACHD Guideline?. ### Response: Stout et al.


Instruction: Why is valve repair preferred to valve replacement?

Output: when it is technically feasible

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is valve repair preferred to valve replacement?. ### Response: when it is technically feasible.


Instruction: There are no large studies on what in patients with AVSD?

Output: residual shunts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are no large studies on what in patients with AVSD?. ### Response: residual shunts.


Instruction: What is likely to result in worsening clinical status over time?

Output: a moderate or large residual shunt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to result in worsening clinical status over time?. ### Response: a moderate or large residual shunt.


Instruction: What should be considered for a moderate or large residual shunt?

Output: repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered for a moderate or large residual shunt?. ### Response: repair.


Instruction: See Sections 4.1.1 and 4.1.3 for related consider-ations regarding what?

Output: ASD and/or VSD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: See Sections 4.1.1 and 4.1.3 for related consider-ations regarding what?. ### Response: ASD and/or VSD.


Instruction: What may identify patients with increased pulmonary resistance and shunt reversal?

Output: Pulse oximetry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may identify patients with increased pulmonary resistance and shunt reversal?. ### Response: Pulse oximetry.


Instruction: What percentage of patients with resting systemic oxygen saturation will have a decrease in oxygen saturation with activity to 90%?

Output: >90%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with resting systemic oxygen saturation will have a decrease in oxygen saturation with activity to 90%?. ### Response: >90%.


Instruction: What is the oxygen saturation with activity to 90%?

Output: <90%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the oxygen saturation with activity to 90%?. ### Response: <90%,.


Instruction: Patients with AVSD are at risk of what?

Output: LVOT obstruc-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with AVSD are at risk of what?. ### Response: LVOT obstruc-tion.


Instruction: What is reasonable when there is moderate-to-severe LVOT obstruction?

Output: Surgical resection of LVOT obstruction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable when there is moderate-to-severe LVOT obstruction?. ### Response: Surgical resection of LVOT obstruction.


Instruction: What is reasonable when there is moderate-to-severe obstruction or less obstruction but associated HF or mitral regurgitation or AR?

Output: Surgical resection of LVOT obstruction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable when there is moderate-to-severe obstruction or less obstruction but associated HF or mitral regurgitation or AR?. ### Response: Surgical resection of LVOT obstruction.


Instruction: In isolated subAS studies, worse outcomes were revealed in patients with maximum gradi-ents 50 mm Hg and with symptoms of HF?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In isolated subAS studies, worse outcomes were revealed in patients with maximum gradi-ents 50 mm Hg and with symptoms of HF?. ### Response: HF.


Instruction: What may not be discrete and surgical repair may be more complex?

Output: LVOT obstruction in AVSD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not be discrete and surgical repair may be more complex?. ### Response: LVOT obstruction in AVSD.


Instruction: When evaluating patients with complex LVOT obstruction, the peak Doppler gradients and Bernoulli equation may inaccurately reflect the severity of what?

Output: ob-struction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When evaluating patients with complex LVOT obstruction, the peak Doppler gradients and Bernoulli equation may inaccurately reflect the severity of what?. ### Response: ob-struction.


Instruction: What may inaccurately reflect the severity of ob-struction?

Output: peak Doppler gradients and Bernoulli equa-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may inaccurately reflect the severity of ob-struction?. ### Response: peak Doppler gradients and Bernoulli equa-tion.


Instruction: Patients with AVSD, particularly those with Down syndrome, are at high risk of developing pulmo-nary vascular disease resulting in Eisenmenger syndrome?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with AVSD, particularly those with Down syndrome, are at high risk of developing pulmo-nary vascular disease resulting in Eisenmenger syndrome?. ### Response: 5.


Instruction: What may prevent exacerbation of PAH?

Output: closure of the defect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may prevent exacerbation of PAH?. ### Response: closure of the defect.


Instruction: What requires collaboration with ACHD and pulmonary hypertension providers?

Output: decision-making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What requires collaboration with ACHD and pulmonary hypertension providers?. ### Response: decision-making.


Instruction: Morbidity and mortality are prohibitively high when surgical repair is attempted in patients with what condition?

Output: open shunts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Morbidity and mortality are prohibitively high when surgical repair is attempted in patients with what condition?. ### Response: open shunts.


Instruction: What is prohibitively high when surgical repair is attempted in patients with open shunts such as AVSD when Eisenmenger syndrome is present?

Output: Morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is prohibitively high when surgical repair is attempted in patients with open shunts such as AVSD when Eisenmenger syndrome is present?. ### Response: Morbidity and mortality.


Instruction: What is summarized in Online Data Supplement 30?

Output: Recommendations for Patent Ductus ArteriosusReferenced studies that support recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is summarized in Online Data Supplement 30?. ### Response: Recommendations for Patent Ductus ArteriosusReferenced studies that support recommendations.


Instruction: What is PR?

Output: pulmonary regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PR?. ### Response: pulmonary regurgitation.


Instruction: What is PS?

Output: pulmonary stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PS?. ### Response: pulmonary stenosis.


Instruction: Where is RVOT located?

Output: right ventricular outflow tract

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is RVOT located?. ### Response: right ventricular outflow tract.


Instruction: When was this article downloaded?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: April 23, 2023.


Instruction: What do Doppler echocardiography and two-dimensional echocardiogra-phy identify the need for?

Output: tricuspid valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do Doppler echocardiography and two-dimensional echocardiogra-phy identify the need for?. ### Response: tricuspid valve repair.


Instruction: What do Chopra HK, Nanda NC, Fan P, et al. do?

Output: two-dimensional echocardiogra-phy and Doppler color flow mapping identify the need for tricuspid valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do Chopra HK, Nanda NC, Fan P, et al. do?. ### Response: two-dimensional echocardiogra-phy and Doppler color flow mapping identify the need for tricuspid valve repair.


Instruction: When did J Am Coll Cardiol. 1989;14:1266–74?

Output: 1989;14:1266–74. 13. Dreyfus GD, Corbi PJ, Chan KMJ, et al. Secondary tricuspid regurgitation or dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 1989;14:1266–74?. ### Response: 1989;14:1266–74. 13. Dreyfus GD, Corbi PJ, Chan KMJ, et al. Secondary tricuspid regurgitation or dilatation.


Instruction: Who is Dreyfus GD?

Output: Secondary tricuspid regurgitation or dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Dreyfus GD?. ### Response: Secondary tricuspid regurgitation or dilatation.


Instruction: What should be the criteria for surgical repair?

Output: Secondary tricuspid regurgitation or dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the criteria for surgical repair?. ### Response: Secondary tricuspid regurgitation or dilatation.


Instruction: What should secondary tricuspid regurgitation or dilatation be considered for?

Output: surgical repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should secondary tricuspid regurgitation or dilatation be considered for?. ### Response: surgical repair.


Instruction: Who recommends the assessment of valvular regur gitation?

Output: European Association of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who recommends the assessment of valvular regur gitation?. ### Response: European Association of Echocardiography.


Instruction: What is the assessment of valvular regur -gitation?

Output: European Association of Echocardiography recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the assessment of valvular regur -gitation?. ### Response: European Association of Echocardiography recommendations.


Instruction: Part 1: aortic and pulmonary regurgitation (native valve disease)?

Output: European Association of Echocardiography recommendations for the assessment of valvular regur -gitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Part 1: aortic and pulmonary regurgitation (native valve disease)?. ### Response: European Association of Echocardiography recommendations for the assessment of valvular regur -gitation.


Instruction: Eur J Echocardiogr. 2010;11:223–44.

Output: Secondary tricuspid regurgitation or dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Eur J Echocardiogr. 2010;11:223–44.. ### Response: Secondary tricuspid regurgitation or dilatation.


Instruction: What is the abbreviation for ACS/H11005acute coronary syndromes?

Output: AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the abbreviation for ACS/H11005acute coronary syndromes?. ### Response: AKI.


Instruction: What is a stent for coronary artery bypass graft surgery?

Output: H11005proton pump inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a stent for coronary artery bypass graft surgery?. ### Response: H11005proton pump inhibitor.


Instruction: What is a major adverse cardiac event?

Output: MI/H11005myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major adverse cardiac event?. ### Response: MI/H11005myocardial infarction.


Instruction: What is an arteryLV/H11005left ventricularLVEF?

Output: ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an arteryLV/H11005left ventricularLVEF?. ### Response: ejection fraction.


Instruction: Where can I find a vascular data registry?

Output: NCDR/H11005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can I find a vascular data registry?. ### Response: NCDR/H11005.


Instruction: When was the data collected?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the data collected?. ### Response: May 1, 2023.


Instruction: #5 Outcomes of interest exp *Cardiovascular Diseases/pc OR exp primary prevention/ OR exp morbidity/ OR ex death/ OR myocardial infarction/ OR cerebrovascular accident/ OR stroke/ OR Angina, Unstable/ OR (stroke* OR (cerebrovascular ADJ accident* OR death OR death) OR (heart ADJ attack*)

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: #5 Outcomes of interest exp *Cardiovascular Diseases/pc OR exp primary prevention/ OR exp morbidity/ OR ex death/ OR myocardial infarction/ OR cerebrovascular accident/ OR stroke/ OR Angina, Unstable/ OR (stroke* OR (cerebrovascular ADJ accident* OR death OR death) OR (heart ADJ attack*). ### Response: mortality.


Instruction: What is another word for heart ADJ attack?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another word for heart ADJ attack?. ### Response: *).


Instruction: What is the other word for myocardial ADJ infarct?

Output: heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the other word for myocardial ADJ infarct?. ### Response: heart.


Instruction: Which word describes secondary ADJ prevention?

Output: OR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which word describes secondary ADJ prevention?. ### Response: OR.


Instruction: What is a primary ADJ prevention?

Output: OR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a primary ADJ prevention?. ### Response: OR.


Instruction: What is angina?

Output: Unstable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is angina?. ### Response: Unstable.


Instruction: How many combine sets?

Output: #6 OR #7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many combine sets?. ### Response: #6 OR #7.


Instruction: A ND #3 AND #4 #8 Combine sets #6 OR #7 #9 Limit to RCTs/SRs/Meta -analysis Randomized controlled trials/systematic review/meta-analysis hedge [see Search Limits at the end of this table]

Output: dyslipidemia terms plus CV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A ND #3 AND #4 #8 Combine sets #6 OR #7 #9 Limit to RCTs/SRs/Meta -analysis Randomized controlled trials/systematic review/meta-analysis hedge [see Search Limits at the end of this table]. ### Response: dyslipidemia terms plus CV.


Instruction: What type of aneurysm surgery in the acute stage: results of structured treatment?

Output: Aneurysm surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of aneurysm surgery in the acute stage: results of structured treatment?. ### Response: Aneurysm surgery.


Instruction: What year did Neurol Med Chir (Tokyo) publish its 38(suppl):45–49.266?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Neurol Med Chir (Tokyo) publish its 38(suppl):45–49.266?. ### Response: 1998.


Instruction: What is the orbitopterional approach to anterior communicatingartery aneurysms?

Output: Anatomic andclinical study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the orbitopterional approach to anterior communicatingartery aneurysms?. ### Response: Anatomic andclinical study.


Instruction: What is a valuable adjunct in an anesthetic surgery?

Output: Fenestration of the lamina terminalis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a valuable adjunct in an anesthetic surgery?. ### Response: Fenestration of the lamina terminalis.


Instruction: When was fenestration of the lamina terminalis avaluable adjunct?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was fenestration of the lamina terminalis avaluable adjunct?. ### Response: 2004.


Instruction: What is shuntdependency after an aneurysmal subarachnoid haemorrhage?

Output: reduces the incidence of shunt-dependenthydrocephalus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shuntdependency after an aneurysmal subarachnoid haemorrhage?. ### Response: reduces the incidence of shunt-dependenthydrocephalus.


Instruction: What is Akyuz M, Tuncer R. The effects of fenestration of the interpeduncularcistern membrane arouse to the opening of lamina terminalis inpatients with ruptured ACoA aneuriesms: a prospective, comparativestudy?

Output: ZentralblNeurochir . 1999;60:133–140.269

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Akyuz M, Tuncer R. The effects of fenestration of the interpeduncularcistern membrane arouse to the opening of lamina terminalis inpatients with ruptured ACoA aneuriesms: a prospective, comparativestudy?. ### Response: ZentralblNeurochir . 1999;60:133–140.269.


Instruction: What is the effect of lamina terminalis fenestration on the occurrence of theshunt-dependent hydrocephalus in anterior communicating artery aneu-rysmal subarachnoid hemorrhage?

Output: reduces the incidence of shunt-dependenthydrocephalus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of lamina terminalis fenestration on the occurrence of theshunt-dependent hydrocephalus in anterior communicating artery aneu-rysmal subarachnoid hemorrhage?. ### Response: reduces the incidence of shunt-dependenthydrocephalus.


Instruction: What reduces the incidence of shunt-dependenthydrocephalus after aneurysmal subarachnoid hemorrhage?

Output: Microsurgical fenes-tration of the lamina terminalis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduces the incidence of shunt-dependenthydrocephalus after aneurysmal subarachnoid hemorrhage?. ### Response: Microsurgical fenes-tration of the lamina terminalis.


Instruction: What does microsurgical fenes-tration of the lamina terminalis reduce?

Output: the incidence of shunt-dependenthydrocephalus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does microsurgical fenes-tration of the lamina terminalis reduce?. ### Response: the incidence of shunt-dependenthydrocephalus.


Instruction: What is the name of the aneurysmal subarachnoid hemor-rhage?

Output: CNS hemor-rhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the aneurysmal subarachnoid hemor-rhage?. ### Response: CNS hemor-rhage.


Instruction: What is a neurosurgery specialty?

Output: Anticonvulsant prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a neurosurgery specialty?. ### Response: Anticonvulsant prophylaxis.


Instruction: Who is the author of Anticonvulsant prophylaxis?

Output: Deutschman CS, Haines SJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Anticonvulsant prophylaxis?. ### Response: Deutschman CS, Haines SJ.


Instruction: What predicts pooroutcome after subarachnoid hemorrhage?

Output: Onset seizures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts pooroutcome after subarachnoid hemorrhage?. ### Response: Onset seizures.


Instruction: What are the incidence andrisk factors of seizures and pelvipsy following aneurysmal?

Output: shuntdependency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the incidence andrisk factors of seizures and pelvipsy following aneurysmal?. ### Response: shuntdependency.


Instruction: What is andepilepsy following aneurysmal subarachnoid hemorrhage?

Output: Seizures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is andepilepsy following aneurysmal subarachnoid hemorrhage?. ### Response: Seizures.


Instruction: What is the incidence andrisk factor for epilepsy?

Output: Seizures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence andrisk factor for epilepsy?. ### Response: Seizures.


Instruction: When was the J Korean Neurosurg Soc published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Korean Neurosurg Soc published?. ### Response: 2009.


Instruction: What is anticonvulsant prophylaxis and timing of seizures after aneu-rysmal subarachnoid hemorrhage?

Output: Onset seizures independently predict pooroutcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is anticonvulsant prophylaxis and timing of seizures after aneu-rysmal subarachnoid hemorrhage?. ### Response: Onset seizures independently predict pooroutcome.


Instruction: What is Epilepsy after operative treatment of?

Output: rupturedcerebral aneurysms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Epilepsy after operative treatment of?. ### Response: rupturedcerebral aneurysms.


Instruction: What year did 106:115–118.280 occur?

Output: 1990

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did 106:115–118.280 occur?. ### Response: 1990.


Instruction: What is the name of the author of the study?

Output: Zuccarello M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the author of the study?. ### Response: Zuccarello M.


Instruction: What isn't a common problem in CKD patients?

Output: hypermagnesemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isn't a common problem in CKD patients?. ### Response: hypermagnesemia.


Instruction: What can't be recommended without specific data showing hypermagnesemia?

Output: magnesium supplemen-tation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can't be recommended without specific data showing hypermagnesemia?. ### Response: magnesium supplemen-tation.


Instruction: What can't be recommended without specific data showing its safety and efficacy?

Output: magnesium supplemen-tation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can't be recommended without specific data showing its safety and efficacy?. ### Response: magnesium supplemen-tation.


Instruction: What has been shown to produce small but significant reductions in BP in a number of RCTsand systematic reviews?

Output: Fish-oil supplementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to produce small but significant reductions in BP in a number of RCTsand systematic reviews?. ### Response: Fish-oil supplementation.


Instruction: What has not been clearly demonstrated in CKD patients?

Output: The optimal timing of administration of medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been clearly demonstrated in CKD patients?. ### Response: The optimal timing of administration of medication.


Instruction: Fish oil exists for patients with what type of disease?

Output: IgAnephropathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fish oil exists for patients with what type of disease?. ### Response: IgAnephropathy.


Instruction: What is premature to recommend this treatment for?

Output: BP lowering in the CKD population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is premature to recommend this treatment for?. ### Response: BP lowering in the CKD population.


Instruction: How many antihypertensive agents do most patients need to achieve their BP targets?

Output: two ormore

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many antihypertensive agents do most patients need to achieve their BP targets?. ### Response: two ormore.


Instruction: How many agents are frequently needed in CKD patients?

Output: three or more

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many agents are frequently needed in CKD patients?. ### Response: three or more.


Instruction: What are the exceptions to ARBs?

Output: ACE-Is in CKD patients with high levels of urinary albumin orprotein excretion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the exceptions to ARBs?. ### Response: ACE-Is in CKD patients with high levels of urinary albumin orprotein excretion.


Instruction: What are frequently needed in CKD patients?

Output: three or moreagents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are frequently needed in CKD patients?. ### Response: three or moreagents.


Instruction: What are the exceptions to ARBs andACE-Is?

Output: high levels of urinary albumin orprotein excretion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the exceptions to ARBs andACE-Is?. ### Response: high levels of urinary albumin orprotein excretion.


Instruction: In CKDD patients with high levels of urinary albumin orprotein excretion, what is the only strong evidence to support the preferential use of agents?

Output: ARBs orACE-Is

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In CKDD patients with high levels of urinary albumin orprotein excretion, what is the only strong evidence to support the preferential use of agents?. ### Response: ARBs orACE-Is.


Instruction: When was the KDOQIGuideline1 published?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the KDOQIGuideline1 published?. ### Response: 2004.


Instruction: What has been an increasing trend toward tailoring antihypertensive therapy to the individualpatient?

Output: Since the 2004 KDOQIGuideline1was published

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been an increasing trend toward tailoring antihypertensive therapy to the individualpatient?. ### Response: Since the 2004 KDOQIGuideline1was published.


Instruction: What is less important than the actual reduction in BP achieved?

Output: the choice of agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less important than the actual reduction in BP achieved?. ### Response: the choice of agents.


Instruction: What is the major measurable outcome in the individual patient?

Output: BP reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the major measurable outcome in the individual patient?. ### Response: BP reduction.


Instruction: Data on drug half-life and doseadjustments in CKD stage 5D may be of help in guiding the use of what drugs?

Output: BP lowering drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data on drug half-life and doseadjustments in CKD stage 5D may be of help in guiding the use of what drugs?. ### Response: BP lowering drugs.


Instruction: What has not been studied in patients who have advancedCKD ND?

Output: The optimal timing of administration of medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been studied in patients who have advancedCKD ND?. ### Response: The optimal timing of administration of medication.


Instruction: How has the optimal timing of administration of medication been studied?

Output: not been studied in CKD patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How has the optimal timing of administration of medication been studied?. ### Response: not been studied in CKD patients.


Instruction: What has not been studied in CKD patients?

Output: The optimal timing of administration of medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been studied in CKD patients?. ### Response: The optimal timing of administration of medication.


Instruction: What do non-dippers and reverse dippers have worse cardiovascular and kidneyoutcomes when compared to?

Output: dippers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do non-dippers and reverse dippers have worse cardiovascular and kidneyoutcomes when compared to?. ### Response: dippers.


Instruction: What has been described in individuals with essential hypertension?

Output: reduction in BP achieved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been described in individuals with essential hypertension?. ### Response: reduction in BP achieved.


Instruction: What was not asked to search for?

Output: evidence of

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not asked to search for?. ### Response: evidence of.


Instruction: What should be reassessed at periodic intervals?

Output: annually

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be reassessed at periodic intervals?. ### Response: annually.


Instruction: What did not address if there was a role for aspirin, orantiplatelet therapy generally in the treatment of VTE?

Output: Aspirin for Extended Treatment of VTESummary of the EvidenceAT9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not address if there was a role for aspirin, orantiplatelet therapy generally in the treatment of VTE?. ### Response: Aspirin for Extended Treatment of VTESummary of the EvidenceAT9.


Instruction: How many randomized trials have been compared with placebo for the prevention of recurrent VTE inpatients with?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized trials have been compared with placebo for the prevention of recurrent VTE inpatients with?. ### Response: two.


Instruction: How long has aspirin therapy been shown to reduce recurrent VTE?

Output: about one-third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has aspirin therapy been shown to reduce recurrent VTE?. ### Response: about one-third.


Instruction: How much does extendedaspirin treatment reduce the recurrence of VTE by?

Output: more than80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does extendedaspirin treatment reduce the recurrence of VTE by?. ### Response: more than80%.


Instruction: What did the bene fits of aspirine outweigh?

Output: the increase in bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the bene fits of aspirine outweigh?. ### Response: the increase in bleeding.


Instruction: What did the bene fits ofaspirin outweigh the increase in?

Output: bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the bene fits ofaspirin outweigh the increase in?. ### Response: bleeding.


Instruction: What was not statistically signi ficant?

Output: bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not statistically signi ficant?. ### Response: bleeding.


Instruction: How many trials enrolled patients with a first unprovoked VTE who did not have an increased risk of bleeding?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many trials enrolled patients with a first unprovoked VTE who did not have an increased risk of bleeding?. ### Response: two.


Instruction: What is extended anticoagulant therapy expected to reduce recurrent VTE by?

Output: more than80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is extended anticoagulant therapy expected to reduce recurrent VTE by?. ### Response: more than80%.


Instruction: What may be associated with the same risk of bleeding as aspirin?

Output: extended NOAC therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with the same risk of bleeding as aspirin?. ### Response: extended NOAC therapy.


Instruction: What is the net bene fit of aspirin therapy less than in the two trials that evaluatedaspirin for extended treatment of VTE?

Output: increase in bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the net bene fit of aspirin therapy less than in the two trials that evaluatedaspirin for extended treatment of VTE?. ### Response: increase in bleeding.


Instruction: What is the net benefit of extended anticoagulant therapy in patients with VTE?

Output: more than80%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the net benefit of extended anticoagulant therapy in patients with VTE?. ### Response: more than80%.


Instruction: What does not consider aspirin a reasonable alternative to in patients who want extended therapy?

Output: anticoagulant therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not consider aspirin a reasonable alternative to in patients who want extended therapy?. ### Response: anticoagulant therapy.


Instruction: What did the patient decide to stop doing?

Output: 332 Evidence-Based Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the patient decide to stop doing?. ### Response: 332 Evidence-Based Medicine.


Instruction: What was the patient's decision to stop?

Output: 332 Evidence-Based Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the patient's decision to stop?. ### Response: 332 Evidence-Based Medicine.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the name of the Task Force on Clinical Practice Guidelines?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Clinical Practice Guidelines?. ### Response: American College of Cardiology/American Heart Association.


Instruction: What is the diagnosis of Mixed VHD?

Output: 1. Unger P , Rosenhek R, Dedobbeleer C, et al. Management of multiple valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diagnosis of Mixed VHD?. ### Response: 1. Unger P , Rosenhek R, Dedobbeleer C, et al. Management of multiple valve disease.


Instruction: How many years did outcome trends for valve surgery in North America last?

Output: Fifteen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years did outcome trends for valve surgery in North America last?. ### Response: Fifteen.


Instruction: What is Venneri L, Khattar RS, Senior R?

Output: Assessment of complex multi-valve dis-ease and prosthetic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Venneri L, Khattar RS, Senior R?. ### Response: Assessment of complex multi-valve dis-ease and prosthetic valves.


Instruction: What year did Thorac Surg publish a report on valvular heart disease?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Thorac Surg publish a report on valvular heart disease?. ### Response: 2011.


Instruction: What is the name of the study conducted by the EURObservational Research Programe Valvular Heart Disease II Survey?

Output: Contemporary presentation and management of valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study conducted by the EURObservational Research Programe Valvular Heart Disease II Survey?. ### Response: Contemporary presentation and management of valvular heart disease.


Instruction: What is the name of the EURObservational Research Pro-gramme Valvular Heart Disease II Survey?

Output: Iung B, Delgado V, Rosenhek R, et al. Contemporary presentation and management of valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the EURObservational Research Pro-gramme Valvular Heart Disease II Survey?. ### Response: Iung B, Delgado V, Rosenhek R, et al. Contemporary presentation and management of valvular heart disease.


Instruction: What is Circulation. 2019;140:1156–69?

Output: the EURObservational Research Pro-gramme Valvular Heart Disease II Survey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Circulation. 2019;140:1156–69?. ### Response: the EURObservational Research Pro-gramme Valvular Heart Disease II Survey.


Instruction: How is multivalvular disease managed?

Output: Pathophysiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is multivalvular disease managed?. ### Response: Pathophysiology.


Instruction: When was the Nat Rev Cardiol. 2016 published?

Output: 13:429–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Nat Rev Cardiol. 2016 published?. ### Response: 13:429–.


Instruction: What is the outcome of combined stenotic and regurgitant aortic valve disease?

Output: 61:1489–95. 2. Egbe AC, Luis SA, Padang R, et al. Outcomes in moderate mixed aor -tic valve disease: is it time for a paradigm shift

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the outcome of combined stenotic and regurgitant aortic valve disease?. ### Response: 61:1489–95. 2. Egbe AC, Luis SA, Padang R, et al. Outcomes in moderate mixed aor -tic valve disease: is it time for a paradigm shift.


Instruction: When did Egbe AC, Luis SA, Padang R, et al. say it is time for a paradigm shift?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Egbe AC, Luis SA, Padang R, et al. say it is time for a paradigm shift?. ### Response: 2013.


Instruction: What type of valve replacement is superior to double valve replacement?

Output: Mitral valve repair with aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve replacement is superior to double valve replacement?. ### Response: Mitral valve repair with aortic valve replacement.


Instruction: What year did J Thorac Cardiovasc Surg.125:1372–87?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Thorac Cardiovasc Surg.125:1372–87?. ### Response: 2003.


Instruction: What is the name of the aortic valve replacement that was left untreated at the time of a valve replacement?

Output: mitral regurgita-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the aortic valve replacement that was left untreated at the time of a valve replacement?. ### Response: mitral regurgita-tion.


Instruction: What year did the J Thorac Cardiovasc Surg. 2003 issue 125:1372–87?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the J Thorac Cardiovasc Surg. 2003 issue 125:1372–87?. ### Response: 2003.


Instruction: Who was the author of the review of the significant mitral regurgita-tion left unsettled at time of transcatheter valve replace-ment?

Output: Nombela-Franco L

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of the review of the significant mitral regurgita-tion left unsettled at time of transcatheter valve replace-ment?. ### Response: Nombela-Franco L.


Instruction: What year did J Am Coll Cardiol.63:2643-58?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Am Coll Cardiol.63:2643-58?. ### Response: 2014.


Instruction: What is the impact of functional versus or -ganic baseline mitral regurgitation on short- and long-term outcomes?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of functional versus or -ganic baseline mitral regurgitation on short- and long-term outcomes?. ### Response: 3.


Instruction: What did Chakravarty T, Van Belle E, Jilaihawi H, et al. Meta-analysis of the impact of mitral regurgitation on outcomes after transcatheter aortic valve im-plantation. 2015;115:942-9. What did Cortés C, Amat-Santos IJ, Nombela-Franco L, and Cortes C do?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Chakravarty T, Van Belle E, Jilaihawi H, et al. Meta-analysis of the impact of mitral regurgitation on outcomes after transcatheter aortic valve im-plantation. 2015;115:942-9. What did Cortés C, Amat-Santos IJ, Nombela-Franco L, and Cortes C do?. ### Response: 4.


Instruction: What is a prognostic factor for transcatheter aortic valve replacement?

Output: imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prognostic factor for transcatheter aortic valve replacement?. ### Response: imaging.


Instruction: What is the name of the study that compares percutaneous repair and surgery for mitral regurgitation?

Output: EVEREST II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares percutaneous repair and surgery for mitral regurgitation?. ### Response: EVEREST II.


Instruction: How long did EVEREST II last?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did EVEREST II last?. ### Response: 5-year.


Instruction: What year did Coll Cardiol. 201566:2844–54?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Coll Cardiol. 201566:2844–54?. ### Response: 2015.


Instruction: What is the long-term clinical impact of functional cardiomyopathy?

Output: 66:2844–54

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term clinical impact of functional cardiomyopathy?. ### Response: 66:2844–54.


Instruction: What year did Al-Khatib and colleagues publish their 2017 VA/SCD GuidelineCirculation. 2018;138:e272–e391?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Al-Khatib and colleagues publish their 2017 VA/SCD GuidelineCirculation. 2018;138:e272–e391?. ### Response: 2018.


Instruction: What is the BUN of a patient without a history of documented VT/VF?

Output: ≥26 mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BUN of a patient without a history of documented VT/VF?. ### Response: ≥26 mg/dL.


Instruction: How many VPBs on 24-hour Holter recording do patients with NSVT have?

Output: >500

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many VPBs on 24-hour Holter recording do patients with NSVT have?. ### Response: >500.


Instruction: How many VPBs on 24-hour Holter recording?

Output: >500

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many VPBs on 24-hour Holter recording?. ### Response: >500.


Instruction: What did Ranolazine not significantly reduce the primary endpoint of?

Output: VT/VF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Ranolazine not significantly reduce the primary endpoint of?. ### Response: VT/VF.


Instruction: What did not significantly reduce the primary endpoint of VT/VF requiring appro-priate ICD therapy or death?

Output: Ranolazine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not significantly reduce the primary endpoint of VT/VF requiring appro-priate ICD therapy or death?. ### Response: Ranolazine.


Instruction: What was associated with a significant reduction in VT events treated with anti-tachycardia pacing?

Output: ranolazine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a significant reduction in VT events treated with anti-tachycardia pacing?. ### Response: ranolazine.


Instruction: Why are Beta Blockers effective in treating VA?

Output: excellent safety profile and effec-tiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are Beta Blockers effective in treating VA?. ### Response: excellent safety profile and effec-tiveness.


Instruction: What are beta blockers often first-line antiarrhythmic therapy?

Output: reducing the risk of SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are beta blockers often first-line antiarrhythmic therapy?. ### Response: reducing the risk of SCD.


Instruction: What is the effect of adrenergic-receptor blockade on sympathetically mediated triggering mechanisms?

Output: slowing of the sinus rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of adrenergic-receptor blockade on sympathetically mediated triggering mechanisms?. ### Response: slowing of the sinus rate.


Instruction: What does the ryanodine receptor possibly inhibit?

Output: ex-cess calcium release

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ryanodine receptor possibly inhibit?. ### Response: ex-cess calcium release.


Instruction: What does beta blockers reduce in patients with HF with reduced EF?

Output: all-cause mortality and SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does beta blockers reduce in patients with HF with reduced EF?. ### Response: all-cause mortality and SCD.


Instruction: What does early beta blocker use in MI patients have an increased risk of?

Output: shock or death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does early beta blocker use in MI patients have an increased risk of?. ### Response: shock or death.


Instruction: What is the systolic blood pressure 120 mm Hg and heart rate >110 beat/min on presentation?

Output: pres-sure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic blood pressure 120 mm Hg and heart rate >110 beat/min on presentation?. ### Response: pres-sure.


Instruction: What is an increased risk of shock or death?

Output: early beta blocker use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increased risk of shock or death?. ### Response: early beta blocker use.


Instruction: What reduces mortality in the setting of polymorphic VT after MI?

Output: beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduces mortality in the setting of polymorphic VT after MI?. ### Response: beta blockers.


Instruction: Beta blockers suppress VA in some patients with what?

Output: structurally normal hearts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beta blockers suppress VA in some patients with what?. ### Response: structurally normal hearts.


Instruction: What are beta blockers also first-line therapy for?

Output: cardiac channelopathies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are beta blockers also first-line therapy for?. ### Response: cardiac channelopathies.


Instruction: What are some cardiac channelopathies?

Output: long QT syndrome, catecholaminergic polymorphic ventricu-lar tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some cardiac channelopathies?. ### Response: long QT syndrome, catecholaminergic polymorphic ventricu-lar tachycardia.


Instruction: Amiodarone has a wide spectrum of actions that include blockade of beta receptors and sodium, calci-um and potassium currents.

Output: 5.1.3. Amiodarone and SotalolAmiodarone possesses a wide spectrum of actions that include blockade of beta receptors and sodium, calci-um and potassium currents (ie, a multichannel blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Amiodarone has a wide spectrum of actions that include blockade of beta receptors and sodium, calci-um and potassium currents.. ### Response: 5.1.3. Amiodarone and SotalolAmiodarone possesses a wide spectrum of actions that include blockade of beta receptors and sodium, calci-um and potassium currents (ie, a multichannel blocker.


Instruction: What is ami-odarone a multichannel blocker of?

Output: potassium currents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ami-odarone a multichannel blocker of?. ### Response: potassium currents.


Instruction: What is the name of the current that is used to block sodium, calci-um, and potassium?

Output: Amiodarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the current that is used to block sodium, calci-um, and potassium?. ### Response: Amiodarone.


Instruction: Why is the long-term effect on survival controversial?

Output: most studies showing no clear advantage over placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the long-term effect on survival controversial?. ### Response: most studies showing no clear advantage over placebo.


Instruction: How many studies have shown a reduction in SCD?

Output: A few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have shown a reduction in SCD?. ### Response: A few.


Instruction: What drug was used in SCD in patients with LV dysfunction due to prior MI and NICM?

Output: ami-odarone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was used in SCD in patients with LV dysfunction due to prior MI and NICM?. ### Response: ami-odarone.


Instruction: What did SCD-HeFT show no survival benefit from amiodarone compared with placebo?

Output: S5.1.5.2-21–S5.1.5.2-23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did SCD-HeFT show no survival benefit from amiodarone compared with placebo?. ### Response: S5.1.5.2-21–S5.1.5.2-23.


Instruction: Who endorsed a set of patient-centered "Preferred Practices for Care Coordination"?

Output: The National Quality Forum

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who endorsed a set of patient-centered "Preferred Practices for Care Coordination"?. ### Response: The National Quality Forum.


Instruction: What does the National Quality Forum endorse?

Output: a set of patient-centered “Preferred Practices for Care Coordination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the National Quality Forum endorse?. ### Response: a set of patient-centered “Preferred Practices for Care Coordination.


Instruction: What are the detailed specifications needed to achieve the goals of successful care coordination for patients and their families?

Output: Preferred Practices for Care Coordination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the detailed specifications needed to achieve the goals of successful care coordination for patients and their families?. ### Response: Preferred Practices for Care Coordination.


Instruction: What can systems of care designed to support patients with STEMI and other cardiac diseases result in?

Output: signifi-cant improvement in patient outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can systems of care designed to support patients with STEMI and other cardiac diseases result in?. ### Response: signifi-cant improvement in patient outcomes.


Instruction: What must be applied to ensure that all patients with STEMI have full access to?

Output: evidence-based therapies and follow-up care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be applied to ensure that all patients with STEMI have full access to?. ### Response: evidence-based therapies and follow-up care.


Instruction: What is a growing emphasis on penalizing hospitals for?

Output: avoid-able hospital readmissions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a growing emphasis on penalizing hospitals for?. ### Response: avoid-able hospital readmissions.


Instruction: What is the emphasis on penalizing hospitals for?

Output: avoid-able hospital readmissions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the emphasis on penalizing hospitals for?. ### Response: avoid-able hospital readmissions.


Instruction: What is imperative for health systems to work in partnership with?

Output: physicians, nurses, phar -macists, communities, payers, and public agencies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is imperative for health systems to work in partnership with?. ### Response: physicians, nurses, phar -macists, communities, payers, and public agencies.


Instruction: Patients characteristics may be important predictors of what?

Output: read-mission after MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients characteristics may be important predictors of what?. ### Response: read-mission after MI.


Instruction: How many variables have been identified consistently?

Output: only a few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many variables have been identified consistently?. ### Response: only a few.


Instruction: A vali-dated risk-standardized model that uses readmission rates to profile hospitals is not currently available from a policy perspective.

Output: 620,621 From a policy perspective, a vali-dated risk-standardized model that uses readmission rates to profile hospitals is not currently available.12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A vali-dated risk-standardized model that uses readmission rates to profile hospitals is not currently available from a policy perspective.. ### Response: 620,621 From a policy perspective, a vali-dated risk-standardized model that uses readmission rates to profile hospitals is not currently available.12.


Instruction: What has the writing committee identified several areas pertain-ing to?

Output: the management of patients with STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has the writing committee identified several areas pertain-ing to?. ### Response: the management of patients with STEMI.


Instruction: What is the Swedish STEMI registry showing an association with?

Output: increased use of evidence-based treatments and declining mortality rates after STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Swedish STEMI registry showing an association with?. ### Response: increased use of evidence-based treatments and declining mortality rates after STEMI.


Instruction: What is one area that deserves further research?

Output: management of patients with STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one area that deserves further research?. ### Response: management of patients with STEMI.


Instruction: What are the rates after STEMI encouraging?

Output: declining mortality rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the rates after STEMI encouraging?. ### Response: declining mortality rates.


Instruction: How many additional efforts to improve patient outcomes are needed?

Output: 18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many additional efforts to improve patient outcomes are needed?. ### Response: 18.


Instruction: How long are wait times from onset of symptoms to activation of STEMI care pathways?

Output: unacceptably long

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long are wait times from onset of symptoms to activation of STEMI care pathways?. ### Response: unacceptably long.


Instruction: What are multicultural efforts needed to educate, reassure, and motivate at-risk patients and their families?

Output: 51,631

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are multicultural efforts needed to educate, reassure, and motivate at-risk patients and their families?. ### Response: 51,631.


Instruction: What are the cornerstones of secondary prevention?

Output: Comparable efforts to improve adher -ence and attention to healthy lifestyle behaviors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the cornerstones of secondary prevention?. ### Response: Comparable efforts to improve adher -ence and attention to healthy lifestyle behaviors.


Instruction: At what time are efforts to improve adher ence and attention to healthy lifestyle behaviors required?

Output: time of discharge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what time are efforts to improve adher ence and attention to healthy lifestyle behaviors required?. ### Response: time of discharge.


Instruction: What is required at time of discharge and as an integral feature of cardiac rehabilitation programs?

Output: Comparable efforts to improve adher -ence and attention to healthy lifestyle behaviors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required at time of discharge and as an integral feature of cardiac rehabilitation programs?. ### Response: Comparable efforts to improve adher -ence and attention to healthy lifestyle behaviors.


Instruction: What has the adoption of regional systems of care for patients with STEMI proved?

Output: challeng-ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has the adoption of regional systems of care for patients with STEMI proved?. ### Response: challeng-ing.


Instruction: What are common delays to initiation of reperfusion ther-apy?

Output: inappropriate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are common delays to initiation of reperfusion ther-apy?. ### Response: inappropriate.


Instruction: How often do women who are at high risk get aspirin?

Output: daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often do women who are at high risk get aspirin?. ### Response: daily.


Instruction: What is the name of the drug that is taken daily for 12 weeks until the bir th of a baby?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is taken daily for 12 weeks until the bir th of a baby?. ### Response: aspirin.


Instruction: What type of disease is syst emic lupus er ythemat osus or antiphospholipid syndr ome?

Output: autoimmune

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of disease is syst emic lupus er ythemat osus or antiphospholipid syndr ome?. ### Response: autoimmune.


Instruction: What is a type 1 or type 2 diabet es?

Output: type  1 or type  2 diabet es • chronic h yper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a type 1 or type 2 diabet es?. ### Response: type  1 or type  2 diabet es • chronic h yper tension.


Instruction: How much aspirin should a woman take daily for 12 weeks?

Output: 75–150  mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much aspirin should a woman take daily for 12 weeks?. ### Response: 75–150  mg.


Instruction: What is a risk factor for pregnancy?

Output: nulliparity • age 40  years or older

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for pregnancy?. ### Response: nulliparity • age 40  years or older.


Instruction: What is the risk of nulliparity?

Output: age 40  years or older

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of nulliparity?. ### Response: age 40  years or older.


Instruction: What is a risk of pregnancy int erval of mor e than 10 years?

Output: age 40  years or older

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk of pregnancy int erval of mor e than 10 years?. ### Response: age 40  years or older.


Instruction: How much body mass index (BMI) is 35 kg/m2?

Output: 35

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much body mass index (BMI) is 35 kg/m2?. ### Response: 35.


Instruction: What is the BMI of a woman?

Output: 35  kg/m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BMI of a woman?. ### Response: 35  kg/m2.


Instruction: What is a family hist ory of pr e-eclampsia?

Output: multi-f etal pr egnancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a family hist ory of pr e-eclampsia?. ### Response: multi-f etal pr egnancy.


Instruction: What type of donors are used to prevent hyper tension during pregnancy?

Output: nitric o xide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of donors are used to prevent hyper tension during pregnancy?. ### Response: nitric o xide.


Instruction: What type o xide donor is used?

Output: nitric

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type o xide donor is used?. ### Response: nitric.


Instruction: How many molecular w eight heparins are used in pregnancy to prevent hyper tension?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many molecular w eight heparins are used in pregnancy to prevent hyper tension?. ### Response: low.


Instruction: What year were all rights reserved?

Output: 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year were all rights reserved?. ### Response: 2023.


Instruction: When was the last updat ed?

Output: 17 April 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed?. ### Response: 17 April 2023.


Instruction: What should be performed in patients with Staphylococcus aureus bacteremia without a known source?

Output: antibiotic regimen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed in patients with Staphylococcus aureus bacteremia without a known source?. ### Response: antibiotic regimen.


Instruction: What is reasonable to diagnose possible IE?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to diagnose possible IE?. ### Response: TEE.


Instruction: What is reasonable to aid in the diagnosis of IE without bacteremia or a new murmur?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to aid in the diagnosis of IE without bacteremia or a new murmur?. ### Response: TEE.


Instruction: CT imaging is reasonable in patients in whom the anatomy cannot be clearly delineated by echocardiography in the setting of suspected paravalvular infections?

Output: 37,61–682a B-NR13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CT imaging is reasonable in patients in whom the anatomy cannot be clearly delineated by echocardiography in the setting of suspected paravalvular infections?. ### Response: 37,61–682a B-NR13.


Instruction: What is reasonable in patients with S. aureus bacteremia with a known portal of entry from an extracardiac source?

Output: CT imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in patients with S. aureus bacteremia with a known portal of entry from an extracardiac source?. ### Response: CT imaging.


Instruction: How is 18F-fluorodeoxyglucose PET/CT reasonable as adjunct diagnostic imaging?

Output: In patients classified by Modified Duke Criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is 18F-fluorodeoxyglucose PET/CT reasonable as adjunct diagnostic imaging?. ### Response: In patients classified by Modified Duke Criteria.


Instruction: What might be considered to detect concomitant staphylococcal IE from an extracardiac source?

Output: TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered to detect concomitant staphylococcal IE from an extracardiac source?. ### Response: TEE.


Instruction: What are the Modified Duke Criteria?

Output: Tables 24 and 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Modified Duke Criteria?. ### Response: Tables 24 and 25.


Instruction: What has been well validated by comparison with surgical or autopsy findings?

Output: Modified Duke Criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been well validated by comparison with surgical or autopsy findings?. ### Response: Modified Duke Criteria.


Instruction: What is included in numerous studies involving a wide spectrum of patients?

Output: clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in numerous studies involving a wide spectrum of patients?. ### Response: clinical outcomes.


Instruction: What is ob-tain for patients with VHD and suspected IE before initiation of antibiotic therapy?

Output: blood culture results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ob-tain for patients with VHD and suspected IE before initiation of antibiotic therapy?. ### Response: blood culture results.


Instruction: What can provide advanced approaches to diagnosis and management of patients with IE?

Output: Modified Duke Criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can provide advanced approaches to diagnosis and management of patients with IE?. ### Response: Modified Duke Criteria.


Instruction: What type of imaging is critical for diagnosis of IE?

Output: Cardiac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of imaging is critical for diagnosis of IE?. ### Response: Cardiac.


Instruction: What percentage of patients with IE have positive blood culture results?

Output: 90%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with IE have positive blood culture results?. ### Response: 90%.


Instruction: How many blood culture samples should be obtained at different times?

Output: ≥2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many blood culture samples should be obtained at different times?. ### Response: ≥2.


Instruction: How many hours apart should samples be obtained?

Output: >6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours apart should samples be obtained?. ### Response: >6.


Instruction: What is more important than the time interval of the collection of culture samples?

Output: observing strict aseptic tech-nique, avoiding sampling from intravascular lines, and ensuring an adequate volume of blood for the culture sample

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more important than the time interval of the collection of culture samples?. ### Response: observing strict aseptic tech-nique, avoiding sampling from intravascular lines, and ensuring an adequate volume of blood for the culture sample.


Instruction: How long is it no longer necessary to incubate blood culture samples?

Output: >7 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it no longer necessary to incubate blood culture samples?. ### Response: >7 days.


Instruction: What is avoiding sampling from intravascular lines?

Output: observing strict aseptic tech-nique

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is avoiding sampling from intravascular lines?. ### Response: observing strict aseptic tech-nique.


Instruction: How is culture samples observing strict aseptic technique?

Output: avoiding sampling from intravascular lines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is culture samples observing strict aseptic technique?. ### Response: avoiding sampling from intravascular lines.


Instruction: On what date was continuous-monitoring blood culture downloaded from http://ahajournals.org?

Output: April 27, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was continuous-monitoring blood culture downloaded from http://ahajournals.org?. ### Response: April 27, 2023.


Instruction: What type of heart failure is referred to as Advanced heart failure and palliative care?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart failure is referred to as Advanced heart failure and palliative care?. ### Response: Chronic Heart Failure.


Instruction: What is the name of the book that covers advanced heart failure?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that covers advanced heart failure?. ### Response: Chronic Heart Failure.


Instruction: How much does it cost to provide written information for the patient?

Output: cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does it cost to provide written information for the patient?. ### Response: cost.


Instruction: What is written information for the patient and their family and/or carers?

Output: cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is written information for the patient and their family and/or carers?. ### Response: cost.


Instruction: Some information on ICDs is already available from what?

Output: charitable organisations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some information on ICDs is already available from what?. ### Response: charitable organisations.


Instruction: What could be provided if not all aspects are covered from available materials?

Output: further supplementary information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be provided if not all aspects are covered from available materials?. ### Response: further supplementary information.


Instruction: What is likely to require an initial upfront cost to produce a document?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to require an initial upfront cost to produce a document?. ### Response: Chronic Heart Failure.


Instruction: After which printing costs per patient are likely to be small?

Output: an initial  upfront cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After which printing costs per patient are likely to be small?. ### Response: an initial  upfront cost.


Instruction: What can sometimes require longer appointment times and re-visiting?

Output: discussions around whether ICDs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can sometimes require longer appointment times and re-visiting?. ### Response: discussions around whether ICDs.


Instruction: What percentage of heart patients are well informed and allow time for discussion?

Output: 5 -10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of heart patients are well informed and allow time for discussion?. ### Response: 5 -10%.


Instruction: What percentage of heart failure patients have ICDs?

Output: 5 -10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of heart failure patients have ICDs?. ### Response: 5 -10%.


Instruction: What is only likely to be considered in a small proportion each year?

Output: discussion about deactivation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is only likely to be considered in a small proportion each year?. ### Response: discussion about deactivation.


Instruction: The committee did not consider that these recommendations would have a significant impact on what?

Output: resource

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee did not consider that these recommendations would have a significant impact on what?. ### Response: resource.


Instruction: What would have a significant resource impact?

Output: Readily available information could be edited, or further supplementary information could be provided if not all aspects are covered from available materials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would have a significant resource impact?. ### Response: Readily available information could be edited, or further supplementary information could be provided if not all aspects are covered from available materials.


Instruction: What can be challenging for people and their families?

Output: conversations around ICD deactivation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be challenging for people and their families?. ### Response: conversations around ICD deactivation.


Instruction: What may some people require?

Output: specialist psychological support or review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may some people require?. ### Response: specialist psychological support or review.


Instruction: What did the committee acknowledge the Resuscitation Council (UK), the British Cardiovascular Society and the National Council for Palliative Care?

Output: ’s guide for healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee acknowledge the Resuscitation Council (UK), the British Cardiovascular Society and the National Council for Palliative Care?. ### Response: ’s guide for healthcare professionals.


Instruction: -defibrillators towards the end of life http://www.bhrs.com/files/guidelines/C IEDs_Deactivation.pdf?

Output: implantable cardioverter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: -defibrillators towards the end of life http://www.bhrs.com/files/guidelines/C IEDs_Deactivation.pdf?. ### Response: implantable cardioverter.


Instruction: The committee were reassured that the advice outlined in this document was in agreement with what?

Output: the recommendations they had made

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee were reassured that the advice outlined in this document was in agreement with what?. ### Response: the recommendations they had made.


Instruction: What is difficult to predict for people with heart failure?

Output: The disease trajectory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is difficult to predict for people with heart failure?. ### Response: The disease trajectory.


Instruction: What is the uncertainty associated with length of life from diagnosis and often repeated episodes of?

Output: severe deterioration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the uncertainty associated with length of life from diagnosis and often repeated episodes of?. ### Response: severe deterioration.


Instruction: What can create anxiety for both patients and clinicians?

Output: The uncertainty associated with length of life from diagnosis and often repeated episod es of severe deterioration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can create anxiety for both patients and clinicians?. ### Response: The uncertainty associated with length of life from diagnosis and often repeated episod es of severe deterioration.


Instruction: What can prevent optimal advance care planning and targeting of therapies and resources?

Output: The uncertainty associated with length of life from diagnosis and often repeated episod es of severe deterioration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can prevent optimal advance care planning and targeting of therapies and resources?. ### Response: The uncertainty associated with length of life from diagnosis and often repeated episod es of severe deterioration.


Instruction: What are prognostic tools used to identify people entering the last year of life?

Output: prediction tools

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are prognostic tools used to identify people entering the last year of life?. ### Response: prediction tools.


Instruction: There are no national guidelines on the use of what?

Output: prognostic  tools to identify people who are entering the last year of life. Despite some prediction tools

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are no national guidelines on the use of what?. ### Response: prognostic  tools to identify people who are entering the last year of life. Despite some prediction tools.


Instruction: No LV enlargementNormal pulmonary pressureNoneC Asymptomatic severe MRS severe mitral valve prolapse with loss of coaptation or flail leafletRheumatic valve changes with leaflet restriction and loss of what?

Output: central coaptation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No LV enlargementNormal pulmonary pressureNoneC Asymptomatic severe MRS severe mitral valve prolapse with loss of coaptation or flail leafletRheumatic valve changes with leaflet restriction and loss of what?. ### Response: central coaptation.


Instruction: What may be present at rest or with exercise?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be present at rest or with exercise?. ### Response: Pulmonary hypertension.


Instruction: What is symptomatic severe MR?

Output: Severe mitral valve prolapse with loss of coaptation or flail leaflet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is symptomatic severe MR?. ### Response: Severe mitral valve prolapse with loss of coaptation or flail leaflet.


Instruction: What is a symptomatic severe MR with loss of coaptation or flail leafletRheumatic valve changes with leaflet restriction and loss of what?

Output: Severe mitral valve prolapse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a symptomatic severe MR with loss of coaptation or flail leafletRheumatic valve changes with leaflet restriction and loss of what?. ### Response: Severe mitral valve prolapse.


Instruction: What type of jet MR is 40% LA or holosystolic eccentric jet?

Output: Central

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of jet MR is 40% LA or holosystolic eccentric jet?. ### Response: Central.


Instruction: How large is the MRVena contracta?

Output: ≥0.7 cm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How large is the MRVena contracta?. ### Response: ≥0.7 cm.


Instruction: What is the valve hemodynamic criteria for?

Output: assessment of MR severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the valve hemodynamic criteria for?. ### Response: assessment of MR severity.


Instruction: What does ERO indicate?

Output: effective regurgitant orifice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ERO indicate?. ### Response: effective regurgitant orifice.


Instruction: What does LA mean?

Output: left atrium/atrial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LA mean?. ### Response: left atrium/atrial.


Instruction: Infective endocarditis is what?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis is what?. ### Response: IE.


Instruction: What is the acronym for infective endocarditis?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for infective endocarditis?. ### Response: IE.


Instruction: What does LA stand for?

Output: left atrium/atrial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LA stand for?. ### Response: left atrium/atrial.


Instruction: Where is LVEF located?

Output: left ventricular ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is LVEF located?. ### Response: left ventricular ejection fraction.


Instruction: When was MR downloaded?

Output: April 27, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was MR downloaded?. ### Response: April 27, 2023.


Instruction: What is a riskmodi fier if age >65 or additional associated risk?

Output: Female sex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a riskmodi fier if age >65 or additional associated risk?. ### Response: Female sex.


Instruction: What is another term for MI or PAD?

Output: complicated vascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for MI or PAD?. ### Response: complicated vascular disease.


Instruction: What is a riskmodi fier if age >65 or additional associated risk factors are present?

Output: Female sex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a riskmodi fier if age >65 or additional associated risk factors are present?. ### Response: Female sex.


Instruction: Females age 65 with no otherrisk factors are not at excess stroke risk.

Output: 66

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Females age 65 with no otherrisk factors are not at excess stroke risk.. ### Response: 66.