Instruction: What does a group that does not exercise regularly do?

Output: receives a treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a group that does not exercise regularly do?. ### Response: receives a treatment.


Instruction: If the ages of the people in the 2 groups are different, then any difference in heart disease is what?

Output: Comparability  Similarity of the groups in characteristics likely to affect the study results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the ages of the people in the 2 groups are different, then any difference in heart disease is what?. ### Response: Comparability  Similarity of the groups in characteristics likely to affect the study results.


Instruction: What is an atherosclerotic origin of aortic aneurysm?

Output: peripheral artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an atherosclerotic origin of aortic aneurysm?. ### Response: peripheral artery disease.


Instruction: What do the 2018 ACC/AHA Cholesterol Guidelines recommend for high-intensity statin therapy?

Output: atorvastatin 80 mg daily or rosuvastatin 20 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the 2018 ACC/AHA Cholesterol Guidelines recommend for high-intensity statin therapy?. ### Response: atorvastatin 80 mg daily or rosuvastatin 20 mg daily.


Instruction: What type of statin therapy is recommended for moderate-intensity patients?

Output: high-intensity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of statin therapy is recommended for moderate-intensity patients?. ### Response: high-intensity.


Instruction: What is a very high risk condition?

Output: Heterozygous familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a very high risk condition?. ### Response: Heterozygous familial hypercholesterolemia.


Instruction: How many major ASCVD events does a person have that are considered very high-risk?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many major ASCVD events does a person have that are considered very high-risk?. ### Response: 1.


Instruction: What is another name for MI?

Output: peripheral artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for MI?. ### Response: peripheral artery disease.


Instruction: What type of arterial disease is symptomatic peripheral arterial disease?

Output: ankle-brachial index <0.85, or previous revascularization or amputation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of arterial disease is symptomatic peripheral arterial disease?. ### Response: ankle-brachial index <0.85, or previous revascularization or amputation.


Instruction: How old is a person at risk for high-risk conditions?

Output: ≥65 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is a person at risk for high-risk conditions?. ### Response: ≥65 years.


Instruction: What is the estimated glomerular filtration rate of chronic kidney disease?

Output: 15–59 mL ·min−1·1.73 m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the estimated glomerular filtration rate of chronic kidney disease?. ### Response: 15–59 mL ·min−1·1.73 m2.


Instruction: What type of drug is used to lower cholesterol?

Output: high-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of drug is used to lower cholesterol?. ### Response: high-intensity statin therapy.


Instruction: What is the current smoking rate of patients with ASCVD?

Output: 6.8.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current smoking rate of patients with ASCVD?. ### Response: 6.8.2.


Instruction: When will the COR LOE be available for download?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the COR LOE be available for download?. ### Response: April 28, 2023.


Instruction: What is the 2013 ACCF/AHA STEMI Guideline?

Output: e411352

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 ACCF/AHA STEMI Guideline?. ### Response: e411352.


Instruction: What predicts clinical outcome as accurately as later electrocardiographic changes?

Output: Change in ST segment elevation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts clinical outcome as accurately as later electrocardiographic changes?. ### Response: Change in ST segment elevation.


Instruction: How long after thrombolytic initiation does change in ST segment elevation predict clinical outcome?

Output: 60 min-utes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after thrombolytic initiation does change in ST segment elevation predict clinical outcome?. ### Response: 60 min-utes.


Instruction: What is a strong predictor of outcome in patients with acute myocardial infarction?

Output: Extent of early ST seg-ment elevation resolution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strong predictor of outcome in patients with acute myocardial infarction?. ### Response: Extent of early ST seg-ment elevation resolution.


Instruction: What was a substudy of the International Joint Efficacy Comparison of Thrombolytics (INJECT) trial?

Output: compare thrombo-lytic regimens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a substudy of the International Joint Efficacy Comparison of Thrombolytics (INJECT) trial?. ### Response: compare thrombo-lytic regimens.


Instruction: What is the name of the Thrombolytics trial?

Output: International Joint Efficacy Comparison of Thrombolytics (INJECT) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Thrombolytics trial?. ### Response: International Joint Efficacy Comparison of Thrombolytics (INJECT) trial.


Instruction: What is one-year survival following early revascularization for cardiogenic shock?

Output: One-year survival following early revascularization for cardiogenic shock. JAMA. 2001;285:190–2.355

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one-year survival following early revascularization for cardiogenic shock?. ### Response: One-year survival following early revascularization for cardiogenic shock. JAMA. 2001;285:190–2.355.


Instruction: What is therapy for for acute myocardial infarction?

Output: rescue angioplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is therapy for for acute myocardial infarction?. ### Response: rescue angioplasty.


Instruction: What is the N Engl J Med. 2005:353:2758–68.356?

Output: myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2005:353:2758–68.356?. ### Response: myocardial infarction.


Instruction: How is rescue an-gioplasty done after failed fibrinolytic therapy?

Output: repeat fibrinolysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is rescue an-gioplasty done after failed fibrinolytic therapy?. ### Response: repeat fibrinolysis.


Instruction: What year did Cardiol. 2007:49:422–30.357?

Output: J Am Coll Cardiol. 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Cardiol. 2007:49:422–30.357?. ### Response: J Am Coll Cardiol. 2007.


Instruction: What type of approach did Collet J-P, Montalescot G, Le May M, et al. use after fibrinolysis?

Output: multiple meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of approach did Collet J-P, Montalescot G, Le May M, et al. use after fibrinolysis?. ### Response: multiple meta-analyses.


Instruction: When did J Am Coll Cardiol 2006:48:1326–35.358?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol 2006:48:1326–35.358?. ### Response: 2006.


Instruction: What is the name of the NORwegian study on DIstrict treatment of ST-elevation myocardial infarction?

Output: NORDISTEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the NORwegian study on DIstrict treatment of ST-elevation myocardial infarction?. ### Response: NORDISTEMI.


Instruction: What is the difference between routine percutane-ous and standard therapy in ST-segment elevation myocardial infarction?

Output: ischaemia-guided conservative approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between routine percutane-ous and standard therapy in ST-segment elevation myocardial infarction?. ### Response: ischaemia-guided conservative approach.


Instruction: When did Eur Heart J.31:2156–69.360?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J.31:2156–69.360?. ### Response: 2010.


Instruction: What is routine early angio-plasty after fibrinolysis for?

Output: acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is routine early angio-plasty after fibrinolysis for?. ### Response: acute myocardial infarction.


Instruction: When did fibrinolysis for acute myocardial infarction occur?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did fibrinolysis for acute myocardial infarction occur?. ### Response: 2009.


Instruction: When did N Engl J Med. 2009 release 360:2705–18.361.

Output: Routine early angio-plasty after fibrinolysis for acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med. 2009 release 360:2705–18.361.. ### Response: Routine early angio-plasty after fibrinolysis for acute myocardial infarction.


Instruction: What was the name of the study that evaluated immediate angioplasty versus standard therapy after thrombolysis?

Output: NORDISTEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that evaluated immediate angioplasty versus standard therapy after thrombolysis?. ### Response: NORDISTEMI.


Instruction: What is CARESS-in-AMI?

Output: Immediate angioplasty versus standard therapy with rescue angioplasty after thrombolysis in the Com-bined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CARESS-in-AMI?. ### Response: Immediate angioplasty versus standard therapy with rescue angioplasty after thrombolysis in the Com-bined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial.


Instruction: What is GRACIA-1?

Output: a randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GRACIA-1?. ### Response: a randomised controlled trial.


Instruction: How long after thrombolysis does Routine inva-sive strategy versus ischaemia-guided conservative approach take?

Output: 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after thrombolysis does Routine inva-sive strategy versus ischaemia-guided conservative approach take?. ### Response: 24 hours.


Instruction: What is a controlled trial?

Output: randomised

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a controlled trial?. ### Response: randomised.


Instruction: What is the need for hub-and-spoke systems for primary and systematic percutaneous coronary intervention?

Output: Systems of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the need for hub-and-spoke systems for primary and systematic percutaneous coronary intervention?. ### Response: Systems of care.


Instruction: What is the name of the document that the Task Force on Clinical Practice Guidelines produced?

Output: S1.3-4. Jacobs AK, Kushner FG, Ettinger SM, et al. ACCF/AHA clinical prac-tice guideline methodology summit report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that the Task Force on Clinical Practice Guidelines produced?. ### Response: S1.3-4. Jacobs AK, Kushner FG, Ettinger SM, et al. ACCF/AHA clinical prac-tice guideline methodology summit report.


Instruction: What is ACC/AHA's classification sys-tem?

Output: clinical practice guideline recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACC/AHA's classification sys-tem?. ### Response: clinical practice guideline recommendation.


Instruction: When was the report released?

Output: October 31, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the report released?. ### Response: October 31, 2018.


Instruction: What is the name of the Task Force on Clinical Practice Guidelines?

Output: American College of Cardiology Foundation/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Clinical Practice Guidelines?. ### Response: American College of Cardiology Foundation/American Heart Association.


Instruction: How long has the ACC/AHA clinical practice guidelines been in existence?

Output: 30-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has the ACC/AHA clinical practice guidelines been in existence?. ### Response: 30-year.


Instruction: What is the acronym for the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

Output: ACCF/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: ACCF/AHA.


Instruction: What are the acronyms for the ACCF/AHA clinical prac-tice guideline methodology summit?

Output: S1.3-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the acronyms for the ACCF/AHA clinical prac-tice guideline methodology summit?. ### Response: S1.3-4.


Instruction: What are the AHA/ACC/HHS strategies to enhance in patients with car-diovascular disease and comorbid conditions from the American Heart Association, American College of Cardiology, and US Department of Health and Human Services?

Output: application of clinical practice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the AHA/ACC/HHS strategies to enhance in patients with car-diovascular disease and comorbid conditions from the American Heart Association, American College of Cardiology, and US Department of Health and Human Services?. ### Response: application of clinical practice guidelines.


Instruction: What is the Circulation. 2014;130:1662–67.1.3?

Output: Document Review and Approval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Circulation. 2014;130:1662–67.1.3?. ### Response: Document Review and Approval.


Instruction: What is the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force?

Output: Practice Guidelines and the Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force?. ### Response: Practice Guidelines and the Heart Rhythm Society.


Instruction: On Practice Guidelines and the Heart Rhythm Society. Circulation. 2014;130:e199-267. S1.3-2. ACCF/AHA Task Force on Practice Guidelines. Methodology Manual and Policies From which Task Force?

Output: American College of Cardiology/American Heart Association Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On Practice Guidelines and the Heart Rhythm Society. Circulation. 2014;130:e199-267. S1.3-2. ACCF/AHA Task Force on Practice Guidelines. Methodology Manual and Policies From which Task Force?. ### Response: American College of Cardiology/American Heart Association Task Force.


Instruction: American College of Cardiology and American Heart Association. Available at: http://assets.cardiosource.com/Methodology_Manual_for_ACC_AHA_Writing_Committees.pdf and http://professional.heart.org/idc/groups/ahamah-public/

Output: heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: American College of Cardiology and American Heart Association. Available at: http://assets.cardiosource.com/Methodology_Manual_for_ACC_AHA_Writing_Committees.pdf and http://professional.heart.org/idc/groups/ahamah-public/. ### Response: heart.


Instruction: What is the name of the group that drafted the Manual for ACC/AHA Writing Committees?

Output: American College of Cardiology/American Heart Association Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that drafted the Manual for ACC/AHA Writing Committees?. ### Response: American College of Cardiology/American Heart Association Task Force.


Instruction: When did the Manual be accessed?

Output: October 31, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Manual be accessed?. ### Response: October 31, 2018.


Instruction: What did the Task Force on Clinical Practice Guidelines report on?

Output: Further evolution of the ACC/AHA clinical practice guideline recommendation classification system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Task Force on Clinical Practice Guidelines report on?. ### Response: Further evolution of the ACC/AHA clinical practice guideline recommendation classification system.


Instruction: What is the acronym for Clinical Practice Guidelines?

Output: prac-tice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Clinical Practice Guidelines?. ### Response: prac-tice.


Instruction: What are the acronyms for the ACCF/AHA clinical prac-tice guideline methodology summit report?

Output: S1.3-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the acronyms for the ACCF/AHA clinical prac-tice guideline methodology summit report?. ### Response: S1.3-4.


Instruction: What section of the 2014 AF Guideline was updated to balance risks and benefits?

Output: Document Review and Approval S1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section of the 2014 AF Guideline was updated to balance risks and benefits?. ### Response: Document Review and Approval S1.


Instruction: What is a direct oral anticoagulant used for in patients with heart failure?

Output: Balancing Risks and Benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a direct oral anticoagulant used for in patients with heart failure?. ### Response: Balancing Risks and Benefits.


Instruction: Cancer and hematologic disorders may be associated with what?

Output: coagulopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cancer and hematologic disorders may be associated with what?. ### Response: coagulopathy.


Instruction: Vital signs A general physical examination focusing on the head, heart, lungs, abdomen, and extremities A focused neurological examination A structured examination such as the National Institutes of Health Stroke Scale can be completed in what year?

Output: minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Vital signs A general physical examination focusing on the head, heart, lungs, abdomen, and extremities A focused neurological examination A structured examination such as the National Institutes of Health Stroke Scale can be completed in what year?. ### Response: minutes.


Instruction: What can be completed in minutes?

Output: National Institutes of Health Stroke Scale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be completed in minutes?. ### Response: National Institutes of Health Stroke Scale.


Instruction: What allows easy communication of the severity of the event to other caregivers?

Output: National Institutes of Health Stroke Scale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What allows easy communication of the severity of the event to other caregivers?. ### Response: National Institutes of Health Stroke Scale.


Instruction: What is associated with worse outcome16,17 Prothrombin time with INR and an activated partial thromboplastin time Warfarin-related hemorrhages are associated with an increased hematoma volume, greater risk of expansion, and increased morbidity and mortality18,19

Output: Higher serum glucose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with worse outcome16,17 Prothrombin time with INR and an activated partial thromboplastin time Warfarin-related hemorrhages are associated with an increased hematoma volume, greater risk of expansion, and increased morbidity and mortality18,19. ### Response: Higher serum glucose.


Instruction: What is an association between elevated troponin levels and worse outcome?

Output: Cardiac-specific troponin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an association between elevated troponin levels and worse outcome?. ### Response: Cardiac-specific troponin.


Instruction: Toxicology screen to detect what drugs of abuse?

Output: cocaine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Toxicology screen to detect what drugs of abuse?. ### Response: cocaine.


Instruction: What are drugs associated with ICH?

Output: Cocaine and other sympathomimetic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are drugs associated with ICH?. ### Response: Cocaine and other sympathomimetic.


Instruction: What tests are associated with ICH Urinalysis and urine culture?

Output: Cocaine and other sympathomimetic drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tests are associated with ICH Urinalysis and urine culture?. ### Response: Cocaine and other sympathomimetic drugs.


Instruction: What can mark a pregnancy test in a woman of childbearing age?

Output: GCS score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can mark a pregnancy test in a woman of childbearing age?. ### Response: GCS score.


Instruction: ECG abnormalities can mark what?

Output: concomitant myocardial injury

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ECG abnormalities can mark what?. ### Response: concomitant myocardial injury.


Instruction: What can mark concomitant myocardial injury?

Output: ECG abnormalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can mark concomitant myocardial injury?. ### Response: ECG abnormalities.


Instruction: What indicates computed tomography?

Output: CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates computed tomography?. ### Response: CT.


Instruction: Why was the evidence for improvement in class I NYHA graded as low quality?

Output: imprecision and indirectness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the evidence for improvement in class I NYHA graded as low quality?. ### Response: imprecision and indirectness.


Instruction: What was the risk of bias?

Output: lack of blinding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of bias?. ### Response: lack of blinding.


Instruction: The study only reported numbers in class 1 NYHA at the end of the trial rather than all of them?

Output: I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The study only reported numbers in class 1 NYHA at the end of the trial rather than all of them?. ### Response: I.


Instruction: What was the evidence for all outcomes of the trial?

Output: very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the evidence for all outcomes of the trial?. ### Response: very low quality.


Instruction: What did the evidence have for mortality over the duration of the study?

Output: very s erious imprecision and high risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the evidence have for mortality over the duration of the study?. ### Response: very s erious imprecision and high risk of bias.


Instruction: How was the quality of life evidence downgraded?

Output: for imprecision and risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the quality of life evidence downgraded?. ### Response: for imprecision and risk of bias.


Instruction: What is the term for unbalanced baseline characteristics between groups?

Output: bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for unbalanced baseline characteristics between groups?. ### Response: bias.


Instruction: What is pregnancy in women with mechanical heart valve prostheses?

Output: Anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is pregnancy in women with mechanical heart valve prostheses?. ### Response: Anticoagulation.


Instruction: What is hepa-rin used for in pregnant women?

Output: mechanical heart valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hepa-rin used for in pregnant women?. ### Response: mechanical heart valves.


Instruction: How is enoxaparin treated in women with mechanical heart valves during pregnancy?

Output: Low molecular weight heparin for the pro-phylaxis of thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is enoxaparin treated in women with mechanical heart valves during pregnancy?. ### Response: Low molecular weight heparin for the pro-phylaxis of thromboembolism.


Instruction: What is thromboprophylaxis with low molecular weight heparin?

Output: Management of preg-nant women with mechanical heart valve prosthesis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is thromboprophylaxis with low molecular weight heparin?. ### Response: Management of preg-nant women with mechanical heart valve prosthesis.


Instruction: What is the name of the European Society of Cardiology Registry of Pregnancy and Cardiac Disease?

Output: ROPAC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the European Society of Cardiology Registry of Pregnancy and Cardiac Disease?. ### Response: ROPAC.


Instruction: What does ROPAC stand for?

Output: European Society of Cardi-ology Registry of Pregnancy and Cardiac Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ROPAC stand for?. ### Response: European Society of Cardi-ology Registry of Pregnancy and Cardiac Disease.


Instruction: What is the name of the 2015 issue of Circulation?

Output: 132:132–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2015 issue of Circulation?. ### Response: 132:132–.


Instruction: Who is the author of ROPAC?

Output: van Hagen IM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of ROPAC?. ### Response: van Hagen IM.


Instruction: How is anti-Xa monitored in pregnancy?

Output: peak or trough levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is anti-Xa monitored in pregnancy?. ### Response: peak or trough levels.


Instruction: What does the UKOSS stand for?

Output: United Kingdom Obstetric Surveillance System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the UKOSS stand for?. ### Response: United Kingdom Obstetric Surveillance System.


Instruction: What is the name of the prospective population based study?

Output: Pregnancy outcomes in women with mechanical prosthetic heart valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective population based study?. ### Response: Pregnancy outcomes in women with mechanical prosthetic heart valves.


Instruction: What is the UKOSS?

Output: United Kingdom Obstetric Surveillance System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the UKOSS?. ### Response: United Kingdom Obstetric Surveillance System.


Instruction: What is low molecular weight heparin used for?

Output: pro-phylaxis of thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low molecular weight heparin used for?. ### Response: pro-phylaxis of thromboembolism.


Instruction: What is one of the outcomes of anticoagulation in pregnant women with mechanical heart valves?

Output: Maternal and fetal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the outcomes of anticoagulation in pregnant women with mechanical heart valves?. ### Response: Maternal and fetal.


Instruction: What is the name of the journal that studies the effects on the fetal and maternal outcomes?

Output: Am J Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the effects on the fetal and maternal outcomes?. ### Response: Am J Cardiol.


Instruction: How many pregnant women were diagnosed with heart valve complications in 2004?

Output: 747–51

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pregnant women were diagnosed with heart valve complications in 2004?. ### Response: 747–51.


Instruction: What type of heart valves are pregnant women with?

Output: mechanical prosthetic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart valves are pregnant women with?. ### Response: mechanical prosthetic.


Instruction: What is the name of the medical journal that studies the effects of warfarin on the fetus?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the medical journal that studies the effects of warfarin on the fetus?. ### Response: J Am Coll Cardiol.


Instruction: When did the J Am Coll Cardiol issue 33:1637–41?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol issue 33:1637–41?. ### Response: 1999.


Instruction: What is the name of the device used to treat anticoagulation in pregnant women with mechanical heart valve prostheses?

Output: Elkayam U

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the device used to treat anticoagulation in pregnant women with mechanical heart valve prostheses?. ### Response: Elkayam U.


Instruction: When did Heart. 1999:82:23-6?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Heart. 1999:82:23-6?. ### Response: 20.


Instruction: What are the names of the devices used for pregnancy outcomes and cardiac complications?

Output: biologic and mechanical valve prostheses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the devices used for pregnancy outcomes and cardiac complications?. ### Response: biologic and mechanical valve prostheses.


Instruction: What is the name of the fourth edition of the American Soci-ety of Regional Anesthesia and Pain Medicine?

Output: evidence-based guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the fourth edition of the American Soci-ety of Regional Anesthesia and Pain Medicine?. ### Response: evidence-based guidelines.


Instruction: What are the names of the authors of the 2004 edition of BJOG?

Output: Goland S, Schwartzenberg S, Fan J, et al. Monitoring of anti-Xa in preg-nant patients with mechanical prosthetic valves receiving low-molecular-weight heparin: peak or trough levels? J Cardiovasc Pharmacol Ther. 2014;19:451–6. 13. Elkayam U. Anticoagulation therapy for pregnant women with mechani-cal prosthetic heart valves: how to improve safety? J Am Coll Cardiol. 2017;69:2692–5. 14. Vause S, Clarke B, Tower CL, et al. Pregnancy outcomes in women with mechanical prosthetic heart valves: a prospective descriptive population based study using the United Kingdom Obstetric Surveillance System (UKOSS) data collection system. BJOG. 2017;124:1411–9. 15. Oran B, Lee-Parritz A, Ansell J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the 2004 edition of BJOG?. ### Response: Goland S, Schwartzenberg S, Fan J, et al. Monitoring of anti-Xa in preg-nant patients with mechanical prosthetic valves receiving low-molecular-weight heparin: peak or trough levels? J Cardiovasc Pharmacol Ther. 2014;19:451–6. 13. Elkayam U. Anticoagulation therapy for pregnant women with mechani-cal prosthetic heart valves: how to improve safety? J Am Coll Cardiol. 2017;69:2692–5. 14. Vause S, Clarke B, Tower CL, et al. Pregnancy outcomes in women with mechanical prosthetic heart valves: a prospective descriptive population based study using the United Kingdom Obstetric Surveillance System (UKOSS) data collection system. BJOG. 2017;124:1411–9. 15. Oran B, Lee-Parritz A, Ansell J.


Instruction: What are the names of the authors of the paper?

Output: Abildgaard U, Sandset PM, Hammerstrøm J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the paper?. ### Response: Abildgaard U, Sandset PM, Hammerstrøm J.


Instruction: What is the name of the study?

Output: European Society of Cardi-ology Registry of Pregnancy and Cardiac Disease (ROPAC).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: European Society of Cardi-ology Registry of Pregnancy and Cardiac Disease (ROPAC)..


Instruction: What is the short title of the PM-12: Cardiac Rehabilitation ReferralPM-12: AMI: CR Patient Referral From an Inpatient SettingMeasure Description: Percentage of patients hospitalized with AMI who are referred to an outpatient CR/secondary prevention program during their AMI hospital stay?

Output: AHA/ACC STEMI/NSTEMI Measure Set

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the short title of the PM-12: Cardiac Rehabilitation ReferralPM-12: AMI: CR Patient Referral From an Inpatient SettingMeasure Description: Percentage of patients hospitalized with AMI who are referred to an outpatient CR/secondary prevention program during their AMI hospital stay?. ### Response: AHA/ACC STEMI/NSTEMI Measure Set.


Instruction: What are AMI patients referred to during their AMI hospital stay?

Output: outpatient CR/secondary prevention program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are AMI patients referred to during their AMI hospital stay?. ### Response: outpatient CR/secondary prevention program.


Instruction: What is the number of hospitalized patients in the reporting period hospitalized with?

Output: qualifying event/diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the number of hospitalized patients in the reporting period hospitalized with?. ### Response: qualifying event/diagnosis.


Instruction: What type of condition or contraindication to exercise are examples of health care system barriers?

Output: high-risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of condition or contraindication to exercise are examples of health care system barriers?. ### Response: high-risk.


Instruction: What is an example of a medical record or other database?

Output: administrative, clinical, registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a medical record or other database?. ### Response: administrative, clinical, registry.


Instruction: At what level is the attribute reported?

Output: facility or provider level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what level is the attribute reported?. ### Response: facility or provider level.


Instruction: What is a key component to outpatient CR program utilization?

Output: the appropriate and timely referral of patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key component to outpatient CR program utilization?. ### Response: the appropriate and timely referral of patients.


Instruction: What is the most important time for a referral to take place?

Output: while the patient is hospitalized for a qualifying event/diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most important time for a referral to take place?. ### Response: while the patient is hospitalized for a qualifying event/diagnosis.


Instruction: What is a qualifying event/diagnosis?

Output: MI, chronic stable angina, CABG, PCI, cardiac valve surgery, or cardiac transplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a qualifying event/diagnosis?. ### Response: MI, chronic stable angina, CABG, PCI, cardiac valve surgery, or cardiac transplantation.


Instruction: What does the performance measure help healthcare systems implement in their systems of care?

Output: effective steps

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the performance measure help healthcare systems implement in their systems of care?. ### Response: effective steps.


Instruction: What will optimize the appropriate referral of a patient to an outpatient CR program?

Output: performance measure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will optimize the appropriate referral of a patient to an outpatient CR program?. ### Response: performance measure.


Instruction: What is designed to serve as a stand-alone measure?

Output: performance measure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is designed to serve as a stand-alone measure?. ### Response: performance measure.


Instruction: What are some conditions for which CR services have been found to be beneficial?

Output: disease states

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some conditions for which CR services have been found to be beneficial?. ### Response: disease states.


Instruction: What is provided in a format that allows easy and flexible inclusion into such performance measurement sets?

Output: performance measure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is provided in a format that allows easy and flexible inclusion into such performance measurement sets?. ### Response: performance measure.


Instruction: What is the responsibility of the healthcare team within a healthcare system?

Output: Effective referral of appropriate inpatients to an outpatient CR program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the responsibility of the healthcare team within a healthcare system?. ### Response: Effective referral of appropriate inpatients to an outpatient CR program.


Instruction: What is primarily responsible for providing cardiovascular care to the patient during the hospitalization?

Output: the healthcare team within a healthcare system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is primarily responsible for providing cardiovascular care to the patient during the hospitalization?. ### Response: the healthcare team within a healthcare system.


Instruction: What should be offered to all eligible patients after CABG?

Output: Cardiac rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be offered to all eligible patients after CABG?. ### Response: Cardiac rehabilitation.


Instruction: What is the Class I, Level of Evidence: B?

Output: Cardiac rehabilitation should be offered to all eligible patients after CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class I, Level of Evidence: B?. ### Response: Cardiac rehabilitation should be offered to all eligible patients after CABG.


Instruction: What type of programs are recommended for high-risk patients?

Output: Advising medically supervised programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of programs are recommended for high-risk patients?. ### Response: Advising medically supervised programs.


Instruction: What is a class I, Level of Evidence: B?

Output: Cardiac rehabilitation should be offered to all eligible patients after CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class I, Level of Evidence: B?. ### Response: Cardiac rehabilitation should be offered to all eligible patients after CABG.


Instruction: What did Whelton and al 2017 High Blood Pressure Clinical Practice Guideline e63all pregnant women for by measuring BP at every prenatal visit?

Output: preeclampsia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Whelton and al 2017 High Blood Pressure Clinical Practice Guideline e63all pregnant women for by measuring BP at every prenatal visit?. ### Response: preeclampsia.


Instruction: What is beyond the scope of the present guideline to address?

Output: the management of hypertension during pregnancy in detail

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beyond the scope of the present guideline to address?. ### Response: the management of hypertension during pregnancy in detail.


Instruction: What does the American College of Obstetricians and Gynecologists recommend for hypertension in pregnancy?

Output: magnesium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American College of Obstetricians and Gynecologists recommend for hypertension in pregnancy?. ### Response: magnesium.


Instruction: What is the name of the task force report that includes recommendations for prevention and treatment of hypertension?

Output: The American College of Obstetricians and Gynecologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the task force report that includes recommendations for prevention and treatment of hypertension?. ### Response: The American College of Obstetricians and Gynecologists.


Instruction: What are ACE inhibitors and ARBs not approved for use during pregnancy?

Output: fetotoxic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ACE inhibitors and ARBs not approved for use during pregnancy?. ### Response: fetotoxic.


Instruction: What is fetotoxic?

Output: ACE inhibitors and ARBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is fetotoxic?. ### Response: ACE inhibitors and ARBs.


Instruction: What is not recommended because potential toxicity differs among agents within classes?

Output: Therapeutic classes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended because potential toxicity differs among agents within classes?. ### Response: Therapeutic classes.


Instruction: What are ACE inhibitors and ARBs fetotoxic in the second and third trimesters of pregnancy?

Output: not approved for use during pregnancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ACE inhibitors and ARBs fetotoxic in the second and third trimesters of pregnancy?. ### Response: not approved for use during pregnancy.


Instruction: What may cause adverse effects in the first trimester of pregnancy?

Output: hypertension or the medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may cause adverse effects in the first trimester of pregnancy?. ### Response: hypertension or the medication.


Instruction: What may be secondary to hypertension or the medication?

Output: Adverse effects in the first trimester of pregnancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be secondary to hypertension or the medication?. ### Response: Adverse effects in the first trimester of pregnancy.


Instruction: Adverse events in the later trimesters have been suggested by observation data and meta-analyses?

Output: S10.2.2-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adverse events in the later trimesters have been suggested by observation data and meta-analyses?. ### Response: S10.2.2-4.


Instruction: For ARBs, case reports with effects similar to ACE inhibitors have been published.

Output: fetotoxic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For ARBs, case reports with effects similar to ACE inhibitors have been published.. ### Response: fetotoxic.


Instruction: What has been published?

Output: case reports with effects similar to ACE inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been published?. ### Response: case reports with effects similar to ACE inhibitors.


Instruction: What are the recommendations for treatment of hypertension in older persons summarized in Online Data Supplement 54?

Output: References that support recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for treatment of hypertension in older persons summarized in Online Data Supplement 54?. ### Response: References that support recommendations.


Instruction: What is recommended for noninstitutionalized ambulatory community-dwelling adults (65 years of age) with an average SBP of 130 mm Hg or higher?

Output: Treatment of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for noninstitutionalized ambulatory community-dwelling adults (65 years of age) with an average SBP of 130 mm Hg or higher?. ### Response: Treatment of hypertension.


Instruction: S10.3.1-1IIa C-EO2 for older adults with hypertension and a high burden of comorbidity and limited life expectancy?

Output: clinical judgment, patient preference, and a team-based approach to assess risk/benefit is reasonable for decisions regarding intensity of BP lowering and choice of antihypertensive drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: S10.3.1-1IIa C-EO2 for older adults with hypertension and a high burden of comorbidity and limited life expectancy?. ### Response: clinical judgment, patient preference, and a team-based approach to assess risk/benefit is reasonable for decisions regarding intensity of BP lowering and choice of antihypertensive drugs.


Instruction: What is reasonable for decisions regarding intensity of BP lowering and choice of antihypertensive drugs?

Output: high burden of comorbidity and limited life expectancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for decisions regarding intensity of BP lowering and choice of antihypertensive drugs?. ### Response: high burden of comorbidity and limited life expectancy.


Instruction: Why is hyper -tension a leading cause of preventable morbidity and mortality?

Output: extremely high prevalence in older adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is hyper -tension a leading cause of preventable morbidity and mortality?. ### Response: extremely high prevalence in older adults.


Instruction: What is a leading cause of preventable morbidity and mortality?

Output: hyper -tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a leading cause of preventable morbidity and mortality?. ### Response: hyper -tension.


Instruction: What is under-recognized as a major contributor to premature disability and institutionalization?

Output: hyper -tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is under-recognized as a major contributor to premature disability and institutionalization?. ### Response: hyper -tension.


Instruction: When do SBP and DBP increase linearly?

Output: up to the fifth or sixth decade of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When do SBP and DBP increase linearly?. ### Response: up to the fifth or sixth decade of life.


Instruction: What is the predominant form of hypertension in older persons?

Output: hyper -tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the predominant form of hypertension in older persons?. ### Response: hyper -tension.


Instruction: What is DBP gradually decreasing after?

Output: the fifth or sixth decade of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DBP gradually decreasing after?. ### Response: the fifth or sixth decade of life.


Instruction: SBP continues to rise after what?

Output: fifth or sixth decade of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: SBP continues to rise after what?. ### Response: fifth or sixth decade of life.


Instruction: Prior mitral valve surgeryComorbidities Severe COPD or home oxygen therapyPulmonary hypertensionSevere RV dysfunction Hepatic dysfunction Frailty*Serious COPD OR Home oxygen therapy Pulmonary HypertensionSerioase RV dysfunctionHepatic functionFrailty *Severate COPD Or Home oxygen Therapy Pulmonaria hypertensionHepatia dysfunctionFraily*Futility STS score >15 What is the comorbidity score for a prior Mitral valve operation

Output: Pulmonary hypertension  Severe RV dysfunction  Hepatic dysfunction  Frailty*

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prior mitral valve surgeryComorbidities Severe COPD or home oxygen therapyPulmonary hypertensionSevere RV dysfunction Hepatic dysfunction Frailty*Serious COPD OR Home oxygen therapy Pulmonary HypertensionSerioase RV dysfunctionHepatic functionFrailty *Severate COPD Or Home oxygen Therapy Pulmonaria hypertensionHepatia dysfunctionFraily*Futility STS score >15 What is the comorbidity score for a prior Mitral valve operation. ### Response: Pulmonary hypertension  Severe RV dysfunction  Hepatic dysfunction  Frailty*.


Instruction: What type of therapy is used to treat Pulmonary hypertension?

Output: home oxygen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is used to treat Pulmonary hypertension?. ### Response: home oxygen.


Instruction: What is the value of a frailty score?

Output: Katz Activities of Daily Living Score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of a frailty score?. ### Response: Katz Activities of Daily Living Score.


Instruction: What is the Katz Activities of Daily Living Score?

Output: Validated frailty scores

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Katz Activities of Daily Living Score?. ### Response: Validated frailty scores.


Instruction: COPD indicates what?

Output: chronic obstructive pulmonary disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: COPD indicates what?. ### Response: chronic obstructive pulmonary disease.


Instruction: SAVR indicates what type of valve replacement?

Output: surgical aortic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: SAVR indicates what type of valve replacement?. ### Response: surgical aortic.


Instruction: STS stands for Society of Thoracic Surgeons.

Output: STS, Society of Thoracic Surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: STS stands for Society of Thoracic Surgeons.. ### Response: STS, Society of Thoracic Surgeons.


Instruction: What is the acronym for transcatheter edge-to-edge repair?

Output: TEER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for transcatheter edge-to-edge repair?. ### Response: TEER.


Instruction: What is another name for tricuspid regurgitation?

Output: TR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for tricuspid regurgitation?. ### Response: TR.


Instruction: When was the STS Adult Cardiac Surgery Database released?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the STS Adult Cardiac Surgery Database released?. ### Response: 2019.


Instruction: What is the acronym for coronary artery bypass graft surgery?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for coronary artery bypass graft surgery?. ### Response: CABG.


Instruction: What does STS stand for?

Output: Society of Thoracic Surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does STS stand for?. ### Response: Society of Thoracic Surgeons.


Instruction: When was this article downloaded?

Output: April 27, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: April 27, 2023.


Instruction: What is the name of the trial that compares dabi-gatran and warfarin in patients with atrial fibrillation and valvular heart disease?

Output: RE-LY Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that compares dabi-gatran and warfarin in patients with atrial fibrillation and valvular heart disease?. ### Response: RE-LY Trial.


Instruction: Who is the author of the RE-LY Trial?

Output: Ezekowitz MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the RE-LY Trial?. ### Response: Ezekowitz MD.


Instruction: Atrial fibrillation and valvular heart disease: the RE-LY Trial.

Output: Comparison of dabi-gatran and warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation and valvular heart disease: the RE-LY Trial.. ### Response: Comparison of dabi-gatran and warfarin.


Instruction: Circulation. 2016;134:589–98.

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2016;134:589–98.. ### Response: 2016.


Instruction: What is the name of the Randomized Evaluation of Long-Term Anticoagulant Therapy?

Output: RE-LY Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Randomized Evaluation of Long-Term Anticoagulant Therapy?. ### Response: RE-LY Trial.


Instruction: What is a systematic review and meta-analysis of valvular heart disease?

Output: Effects of non-vitamin K antagonist oral anticoagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis of valvular heart disease?. ### Response: Effects of non-vitamin K antagonist oral anticoagulants.


Instruction: What is Floyd CN, Ferro A. Indications for anticoagulant and antiplatelet combined therapy?

Output: CHA2DS2-VASc score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Floyd CN, Ferro A. Indications for anticoagulant and antiplatelet combined therapy?. ### Response: CHA2DS2-VASc score.


Instruction: What is the Euro Heart Survey on Atrial Fibrillation based on?

Output: risk factor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Euro Heart Survey on Atrial Fibrillation based on?. ### Response: risk factor.


Instruction: What score is used for refining stroke risk stratification in patients with atrial fibrillation with CHA2DS2-VASc?

Output: CHADS2 score 0–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What score is used for refining stroke risk stratification in patients with atrial fibrillation with CHA2DS2-VASc?. ### Response: CHADS2 score 0–.


Instruction: How is stroke risk stratified in atrial fibrillation patients?

Output: novel risk factor-based approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is stroke risk stratified in atrial fibrillation patients?. ### Response: novel risk factor-based approach.


Instruction: What is the CHADS2 score 0-1?

Output: refining stroke risk stratification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CHADS2 score 0-1?. ### Response: refining stroke risk stratification.


Instruction: How is the impact of CHA2DS2-VASc score on anticoagulation recommendations?

Output: Impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the impact of CHA2DS2-VASc score on anticoagulation recommendations?. ### Response: Impact.


Instruction: What is the name of the disease that causes atrial fibrillation?

Output: valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes atrial fibrillation?. ### Response: valvular heart disease.


Instruction: What are the names of the two drugs used to treat atrial fibrosis?

Output: non-vitamin K antagonist oral anticoagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the two drugs used to treat atrial fibrosis?. ### Response: non-vitamin K antagonist oral anticoagulants.


Instruction: Which drug is better for patients with a heart condition?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug is better for patients with a heart condition?. ### Response: warfarin.


Instruction: In what year did N Engl J Med publish a report on the effectiveness of rivaroxaban versus warfarin?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did N Engl J Med publish a report on the effectiveness of rivaroxaban versus warfarin?. ### Response: 2011.


Instruction: What is the name of the drug used in nonvalvular atrial fibrillation?

Output: Rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used in nonvalvular atrial fibrillation?. ### Response: Rivaroxaban.


Instruction: When was the N Engl J Med 365:883-91?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 365:883-91?. ### Response: 2011.


Instruction: What is edoxaban versus warfarin in patients with atrial fibrosis?

Output: non-vitamin K antagonist oral anticoagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is edoxaban versus warfarin in patients with atrial fibrosis?. ### Response: non-vitamin K antagonist oral anticoagulants.


Instruction: What is the difference between edoxaban and warfarin in atrial fibrillation patients?

Output: non-vitamin K antagonist oral anticoagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between edoxaban and warfarin in atrial fibrillation patients?. ### Response: non-vitamin K antagonist oral anticoagulants.


Instruction: What was the N Engl J Med 2013:369:2093–104?

Output: Edoxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med 2013:369:2093–104?. ### Response: Edoxaban.


Instruction: How did home testing of international normalized ratio affect clinical events?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did home testing of international normalized ratio affect clinical events?. ### Response: Effect.


Instruction: When did N Eng J Med 2010:363:1608–20?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Eng J Med 2010:363:1608–20?. ### Response: 2010.


Instruction: What is the importance of moni-toring?

Output: Initiating and maintain-ing patients on warfarin anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the importance of moni-toring?. ### Response: Initiating and maintain-ing patients on warfarin anticoagulation.


Instruction: What is part 2 of the guide to anticoagulant therapy?

Output: oral anti-coagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is part 2 of the guide to anticoagulant therapy?. ### Response: oral anti-coagulants.


Instruction: Who is the author of the Guide to Anticoagulant Therapy?

Output: Hirsh J, Fuster V

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the Guide to Anticoagulant Therapy?. ### Response: Hirsh J, Fuster V.


Instruction: What is the name of the multicenter randomized comparison of low-dose versus standard-dose anticoagulation in patients with mechanical heart valves?

Output: AREVA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter randomized comparison of low-dose versus standard-dose anticoagulation in patients with mechanical heart valves?. ### Response: AREVA.


Instruction: What is the name of the multicenter randomized comparison of low-dose versus standard-dose anticoagulation in patients with mechanical prosthetic heart valves?

Output: AREVA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter randomized comparison of low-dose versus standard-dose anticoagulation in patients with mechanical prosthetic heart valves?. ### Response: AREVA.


Instruction: What is gical repair in fixed subaortic stenosis?

Output: S4.2.3-6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is gical repair in fixed subaortic stenosis?. ### Response: S4.2.3-6.


Instruction: When did J Am Coll Cardiol. 30:1835-42?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 30:1835-42?. ### Response: 1997.


Instruction: What is the developmental complex of?

Output: parachute mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the developmental complex of?. ### Response: parachute mitral valve.


Instruction: What is supravalvular ring of left atrium, subaortic stenosis, and coarctation of aorta?

Output: The developmental complex of “parachute mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is supravalvular ring of left atrium, subaortic stenosis, and coarctation of aorta?. ### Response: The developmental complex of “parachute mitral valve.


Instruction: When was the Am J Cardiol.11:714–25.

Output: 1963

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol.11:714–25.. ### Response: 1963.


Instruction: What was the 2014 AHA/ACC guideline for?

Output: management of patients with valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2014 AHA/ACC guideline for?. ### Response: management of patients with valvular heart disease.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines recommend for the management of patients with valvular heart di-sease?

Output: AHA/ACC guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines recommend for the management of patients with valvular heart di-sease?. ### Response: AHA/ACC guideline.


Instruction: What did Brodyn NE, Haft JI, describe as a result of membranous sub-aortic stenosis?

Output: Chest pain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Brodyn NE, Haft JI, describe as a result of membranous sub-aortic stenosis?. ### Response: Chest pain.


Instruction: What type of stenosis in young women is a multicentre study?

Output: balloon aortic valvu-loplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stenosis in young women is a multicentre study?. ### Response: balloon aortic valvu-loplasty.


Instruction: What is the morphology of bi-cuspid stenosis?

Output: Morphology of bi-cuspid aortic valve in children and adolescents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the morphology of bi-cuspid stenosis?. ### Response: Morphology of bi-cuspid aortic valve in children and adolescents.


Instruction: What is prevalent in relatives of bicuspid aortic valve patients?

Output: Aortopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is prevalent in relatives of bicuspid aortic valve patients?. ### Response: Aortopathy.


Instruction: What is the name of the disease in children and adolescents?

Output: valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease in children and adolescents?. ### Response: valvular heart disease.


Instruction: When was the J Am Coll Cardiol.44:1648-51?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol.44:1648-51?. ### Response: 2004.


Instruction: What is the name of the prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve in newborns by echocardiographic screening?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve in newborns by echocardiographic screening?. ### Response: J Am Coll Cardiol.


Instruction: What is the frequency of familial clustering of congenital bicuspid aortic valve?

Output: S4.2.4-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the frequency of familial clustering of congenital bicuspid aortic valve?. ### Response: S4.2.4-5.


Instruction: What was the J Am Coll Cardiol. 1997;30:1809-12?

Output: A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol. 1997;30:1809-12?. ### Response: A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve.


Instruction: Who wrote the 2014 AHA/ACC guideline?

Output: Nishimura RA, Otto CM, Bonow RO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the 2014 AHA/ACC guideline?. ### Response: Nishimura RA, Otto CM, Bonow RO.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?

Output: management of patients with valvular heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?. ### Response: management of patients with valvular heart disease.


Instruction: What was the name of the task force on practice guidelines?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the task force on practice guidelines?. ### Response: American College of Cardiology/American Heart Association.


Instruction: When was the document downloaded from the AHAjournals website?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the document downloaded from the AHAjournals website?. ### Response: April 28, 2023.


Instruction: Who is a founding KDIGO Co-Chair?

Output: David C Wheeler, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a founding KDIGO Co-Chair?. ### Response: David C Wheeler, MD.


Instruction: What is the name of the MD who was a co-chair?

Output: David C Wheeler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the MD who was a co-chair?. ### Response: David C Wheeler.


Instruction: Who is an MD who has a PhD?

Output: Adrian Covic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is an MD who has a PhD?. ### Response: Adrian Covic.


Instruction: Which MD has an appointment as a board member?

Output: Garabed Eknoyan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which MD has an appointment as a board member?. ### Response: Garabed Eknoyan.


Instruction: MBA, FACHEDaniel C Cattran, MD, FRCPCAllan J Collins, MD?

Output: Fred Brown

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: MBA, FACHEDaniel C Cattran, MD, FRCPCAllan J Collins, MD?. ### Response: Fred Brown.


Instruction: PhDRicardo Correa-Rotter, MDAdrian Covic, MD and PhDJonathan C Craig, MBChB, MM (Clin Epi), DCH, FRACP, PhDAna Figueiredo, RN, MSc, PhDMohammed Benghanem Gharbi, BSc, FRCPCDavid

Output: ﬁ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PhDRicardo Correa-Rotter, MDAdrian Covic, MD and PhDJonathan C Craig, MBChB, MM (Clin Epi), DCH, FRACP, PhDAna Figueiredo, RN, MSc, PhDMohammed Benghanem Gharbi, BSc, FRCPCDavid. ### Response: ﬁ.


Instruction: What is the title of the doctoral candidate who earned his PhD?

Output: Angela Yee-Moon Wang

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the doctoral candidate who earned his PhD?. ### Response: Angela Yee-Moon Wang.


Instruction: Who is the professor of medicine who received his MSc?

Output: Ana Figueiredo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of medicine who received his MSc?. ### Response: Ana Figueiredo.


Instruction: Who is the MD, FRCP, FACPZhi-Hong Liu, MDPeter A McCullough, MPH, FACC, FACPRafique Moosa, MDMiguel C Riella, MDAdibul Hasan Rizvi, MBBS, FRCPBernardo Rodriquez-Iturbe, MD, PhD?

Output: Philip K-T Li

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the MD, FRCP, FACPZhi-Hong Liu, MDPeter A McCullough, MPH, FACC, FACPRafique Moosa, MDMiguel C Riella, MDAdibul Hasan Rizvi, MBBS, FRCPBernardo Rodriquez-Iturbe, MD, PhD?. ### Response: Philip K-T Li.


Instruction: Who is the Senior Vice-President for Scientific Activities?

Output: Kerry Willis, PhD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Senior Vice-President for Scientific Activities?. ### Response: Kerry Willis, PhD.


Instruction: What is Michael Cheung's profession?

Output: MA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Michael Cheung's profession?. ### Response: MA.


Instruction: What does e564S Antithrombotic Therapy for Atrial Fibrillation not apply to?

Output: patients already receiving warfarin for AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does e564S Antithrombotic Therapy for Atrial Fibrillation not apply to?. ### Response: patients already receiving warfarin for AF.


Instruction: There are no studies comparing warfarin plus aspirin to what?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are no studies comparing warfarin plus aspirin to what?. ### Response: triple therapy.


Instruction: What is a triple therapy?

Output: warfarin, aspirin, and clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a triple therapy?. ### Response: warfarin, aspirin, and clopidogrel.


Instruction: Recent ACS.

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent ACS.. ### Response: 12 months.


Instruction: What would be appropriate if the risk reduction in MI and stroke achieved by adding the second antiplatelet agent is greater than the increase in bleeding risk?

Output: Use of triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be appropriate if the risk reduction in MI and stroke achieved by adding the second antiplatelet agent is greater than the increase in bleeding risk?. ### Response: Use of triple therapy.


Instruction: What are patients who are not under-going stent placement?

Output: Patients With AF and ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients who are not under-going stent placement?. ### Response: Patients With AF and ACS.


Instruction: What is the principle to fi rst do no harm?

Output: mindful

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the principle to fi rst do no harm?. ### Response: mindful.


Instruction: Why do we not advocate the use of triple therapy?

Output: Given the lack of direct evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do we not advocate the use of triple therapy?. ### Response: Given the lack of direct evidence.


Instruction: What type of stent is not used in patients with AF with ACS?

Output: intracoronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stent is not used in patients with AF with ACS?. ### Response: intracoronary.


Instruction: What are patients who place a high value on on MI and stroke reduc-tion and a low value on avoiding bleeding likely to opt for?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients who place a high value on on MI and stroke reduc-tion and a low value on avoiding bleeding likely to opt for?. ### Response: triple therapy.


Instruction: How long is the initial period of triple therapy?

Output: 3-6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the initial period of triple therapy?. ### Response: 3-6 months.


Instruction: Which drug is followed by warfarin?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug is followed by warfarin?. ### Response: aspirin.


Instruction: What type of therapy is recommended for patients with AF at intermediate to high risk of stroke?

Output: antithrombotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is recommended for patients with AF at intermediate to high risk of stroke?. ### Response: antithrombotic therapy.


Instruction: What is a CHADS score of 1 or greater?

Output: CHADS 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a CHADS score of 1 or greater?. ### Response: CHADS 2.


Instruction: How long is the period of triple therapy?

Output: 3-6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the period of triple therapy?. ### Response: 3-6 months.


Instruction: What type of therapy is recommended for patients with acute coronary syndrome?

Output: antithrombotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is recommended for patients with acute coronary syndrome?. ### Response: antithrombotic therapy.


Instruction: What is the INR of VKA therapy?

Output: 2.0-3.0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the INR of VKA therapy?. ### Response: 2.0-3.0.


Instruction: How long does it take to get an adjusted-dose VKA treatment?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to get an adjusted-dose VKA treatment?. ### Response: 12 months.


Instruction: What is grade 2C?

Output: dual anti-platelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is grade 2C?. ### Response: dual anti-platelet therapy.


Instruction: What is suggested for patients with AF and stable coronary artery disease after fi rst 12 months?

Output: antithrom-botic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is suggested for patients with AF and stable coronary artery disease after fi rst 12 months?. ### Response: antithrom-botic therapy.


Instruction: What is a CHADS 2 score of 0?

Output: low risk of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a CHADS 2 score of 0?. ### Response: low risk of stroke.


Instruction: What is another name for dual anti-platelet therapy?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for dual anti-platelet therapy?. ### Response: triple therapy.


Instruction: How is adjusted-dose VKA therapy calculated?

Output: INR 2.0-3.0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is adjusted-dose VKA therapy calculated?. ### Response: INR 2.0-3.0.


Instruction: What is the grade 2C of clopid-ogrel?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the grade 2C of clopid-ogrel?. ### Response: triple therapy.


Instruction: What is suggested for patients with AF and stable coronary artery disease?

Output: ithrom-botic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is suggested for patients with AF and stable coronary artery disease?. ### Response: ithrom-botic therapy.


Instruction: What do people who place a high value on stroke reduction and a low value on avoid-ing bleeding and the burden associated with antico-agulant therapy choose?

Output: adjusted-dose VKA therapy plus single antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do people who place a high value on stroke reduction and a low value on avoid-ing bleeding and the burden associated with antico-agulant therapy choose?. ### Response: adjusted-dose VKA therapy plus single antiplatelet therapy.


Instruction: Adjusted-dose VKA therapy plus single antiplatelet therapy is a better option than what?

Output: dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adjusted-dose VKA therapy plus single antiplatelet therapy is a better option than what?. ### Response: dual antiplatelet therapy.


Instruction: What factors may infl uence this choice?

Output: patients placing a high value on MI and stroke reduc-tion and a low value on avoiding bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What factors may infl uence this choice?. ### Response: patients placing a high value on MI and stroke reduc-tion and a low value on avoiding bleeding.


Instruction: What are two factors that may infl uence this choice?

Output: MI and stroke reduc-tion and a low value on avoiding bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two factors that may infl uence this choice?. ### Response: MI and stroke reduc-tion and a low value on avoiding bleeding.


Instruction: What is bleed-ing risk and the presence of additional non-CHADS 2 risk factors for?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is bleed-ing risk and the presence of additional non-CHADS 2 risk factors for?. ### Response: stroke.


Instruction: Other fac-tors that are likely to choose triple therapy are what?

Output: a consider-ation of bleeding risk and the presence of additional non-CHADS 2  risk factors for stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Other fac-tors that are likely to choose triple therapy are what?. ### Response: a consider-ation of bleeding risk and the presence of additional non-CHADS 2  risk factors for stroke.


Instruction: What is a risk factor for stroke that may be considered in triple therapy?

Output: non-CHADS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for stroke that may be considered in triple therapy?. ### Response: non-CHADS.


Instruction: What is another factor that may influence the triple therapy option?

Output: patients placing a high value on MI and stroke reduc-tion and a low value on avoiding bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another factor that may influence the triple therapy option?. ### Response: patients placing a high value on MI and stroke reduc-tion and a low value on avoiding bleeding.


Instruction: Patients With AF and ACS Who Do Not Undergo Intracoronary Stent Should Consider a consideration of bleeding risk and the presence of what?

Output: antico-agulant therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients With AF and ACS Who Do Not Undergo Intracoronary Stent Should Consider a consideration of bleeding risk and the presence of what?. ### Response: antico-agulant therapy.


Instruction: AF and ACS Who Do Not Undergo Intracoronary Stent Placement?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AF and ACS Who Do Not Undergo Intracoronary Stent Placement?. ### Response: patients.


Instruction: How many patients were diagnosed with TIA and carotid stenosis in a Kaiser Permanente cohort study?

Output: 299

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were diagnosed with TIA and carotid stenosis in a Kaiser Permanente cohort study?. ### Response: 299.


Instruction: What percentage of patients were women?

Output: 47%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients were women?. ### Response: 47%).


Instruction: Women were less likely to undergo what type of treatment?

Output: CEA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Women were less likely to undergo what type of treatment?. ### Response: CEA.


Instruction: What percentage of CEA patients were women?

Output: 47%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of CEA patients were women?. ### Response: 47%).


Instruction: What was an independent predictor for not receiving CEA after adjustment for age, number of TIAs, specificity of symptoms, and degree of stenosis?

Output: female

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was an independent predictor for not receiving CEA after adjustment for age, number of TIAs, specificity of symptoms, and degree of stenosis?. ### Response: female.


Instruction: Who was less likely to undergo CEA?

Output: Women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was less likely to undergo CEA?. ### Response: Women.


Instruction: How long was the time to surgery in women who underwent CEA?

Output: 35 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the time to surgery in women who underwent CEA?. ### Response: 35 days.


Instruction: What was the mean of the time it took for women to undergo CEA than in men?

Output: 35 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean of the time it took for women to undergo CEA than in men?. ### Response: 35 days.


Instruction: How long is the current recommendation to perform CEA within 2 weeks of symptoms of TIA or mild stroke?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the current recommendation to perform CEA within 2 weeks of symptoms of TIA or mild stroke?. ### Response: 20.


Instruction: What is TIA?

Output: carotid stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TIA?. ### Response: carotid stenosis.


Instruction: What is mild stroke?

Output: TIA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is mild stroke?. ### Response: TIA.


Instruction: In the surgical subgroup, women were older and less likely to have what?

Output: coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the surgical subgroup, women were older and less likely to have what?. ### Response: coronary artery disease.