Instruction: What does the USPSTF recommend that clini-cians direct patients who smoke tobacco to?

Output: other cessation interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the USPSTF recommend that clini-cians direct patients who smoke tobacco to?. ### Response: other cessation interventions.


Instruction: What is a strong, independent risk factor for ASCVD events?

Output: Cigarette smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strong, independent risk factor for ASCVD events?. ### Response: Cigarette smoking.


Instruction: What is a strong, indepen-dent risk factor for ASCVD events and premature death?

Output: Cigarette smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strong, indepen-dent risk factor for ASCVD events and premature death?. ### Response: Cigarette smoking.


Instruction: What is beneficial even among older adults in reducing excess risk?

Output: tobacco ces-sation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial even among older adults in reducing excess risk?. ### Response: tobacco ces-sation.


Instruction: How many years of tobacco cessation did never smokers have?

Output: >15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of tobacco cessation did never smokers have?. ### Response: >15.


Instruction: In the National Health Interview Survey, smoking was strongly associated with what in young people?

Output: ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the National Health Interview Survey, smoking was strongly associated with what in young people?. ### Response: ASCVD.


Instruction: What is tobacco use dependence?

Output: a chronic disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tobacco use dependence?. ### Response: a chronic disease.


Instruction: What is a chronic disease that requires highly skilled chronic disease man-agement?

Output: Tobacco use dependence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a chronic disease that requires highly skilled chronic disease man-agement?. ### Response: Tobacco use dependence.


Instruction: What should every health system or practice dedicate trained staff to?

Output: tobacco treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should every health system or practice dedicate trained staff to?. ### Response: tobacco treatment.


Instruction: Healthcare profesionals who receive training in tobacco treatment are more likely to ask about what?

Output: tobacco use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Healthcare profesionals who receive training in tobacco treatment are more likely to ask about what?. ### Response: tobacco use.


Instruction: Who are more likely to ask about tobacco use, offer advice to quit, provide behavioral interventions, follow up with individuals and increase the number of tobacco users who quit?

Output: Healthcare profes-sionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who are more likely to ask about tobacco use, offer advice to quit, provide behavioral interventions, follow up with individuals and increase the number of tobacco users who quit?. ### Response: Healthcare profes-sionals.


Instruction: What do participants who earn a certificate in tobacco treatment practice demonstrate?

Output: a nationally recognized level of training and skill acquisition in treating tobacco dependence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do participants who earn a certificate in tobacco treatment practice demonstrate?. ### Response: a nationally recognized level of training and skill acquisition in treating tobacco dependence.


Instruction: What is a national recognized level of training and skill acquisition in treating tobacco dependence?

Output: Participants who earn a certificate in tobacco treatment practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a national recognized level of training and skill acquisition in treating tobacco dependence?. ### Response: Participants who earn a certificate in tobacco treatment practice.


Instruction: A Tobacco Treatment Specialist possesses the skills, knowledge, and training to provide effic-tive, evidence-based interventions for tobacco dependence across a range of intensities?

Output: s4.5-27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A Tobacco Treatment Specialist possesses the skills, knowledge, and training to provide effic-tive, evidence-based interventions for tobacco dependence across a range of intensities?. ### Response: s4.5-27.


Instruction: What type of program is available at http://ctttp.org/accredited-programs.S4.5-29Table 8 highlights of recommended behavioral and pharmacotherapy Tobacco Treatment Modalities for Prescribers?

Output: Tobacco Treatment Specialist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of program is available at http://ctttp.org/accredited-programs.S4.5-29Table 8 highlights of recommended behavioral and pharmacotherapy Tobacco Treatment Modalities for Prescribers?. ### Response: Tobacco Treatment Specialist.


Instruction: How long of tobacco status assessment with cessation counseling at each clinic encounter?

Output: >3-10 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long of tobacco status assessment with cessation counseling at each clinic encounter?. ### Response: >3-10 min.


Instruction: What is the starting dose for 10 CPD?

Output: 21 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the starting dose for 10 CPD?. ### Response: 21 mg.


Instruction: What is a possible side effect of 14 mg of CPDLocal irritation?

Output: skin disorders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible side effect of 14 mg of CPDLocal irritation?. ### Response: skin disorders.


Instruction: How long after waking is the first dose of tobacco used?

Output: ≤30 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after waking is the first dose of tobacco used?. ### Response: ≤30 min.


Instruction: How many lozenges or 24 pieces of tobacco can be used at a time?

Output: S4.5-24

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many lozenges or 24 pieces of tobacco can be used at a time?. ### Response: S4.5-24.


Instruction: For CPDLocal irritation possible; avoid with what?

Output: skin disorders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For CPDLocal irritation possible; avoid with what?. ### Response: skin disorders.


Instruction: What is the maximum amount of lozenges?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum amount of lozenges?. ### Response: 20.


Instruction: How many pieces of gum per day?

Output: 24

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pieces of gum per day?. ### Response: 24.


Instruction: What do studies use to evaluate sodium intake?

Output: pot urine sodium measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do studies use to evaluate sodium intake?. ### Response: pot urine sodium measurements.


Instruction: What is the current controversy about assessing sodium intake using random “spot”urine samples?

Output: the accuracy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current controversy about assessing sodium intake using random “spot”urine samples?. ### Response: the accuracy.


Instruction: What is required to evaluate the health impacts of very low-sodium intakes in CKDpopulations?

Output: Future studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required to evaluate the health impacts of very low-sodium intakes in CKDpopulations?. ### Response: Future studies.


Instruction: Recent small, single-center clinical trials evaluating chronicoral sodium bicarbonate supplementationversus placebo have not found changes in what?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent small, single-center clinical trials evaluating chronicoral sodium bicarbonate supplementationversus placebo have not found changes in what?. ### Response: BP.


Instruction: What may be associated with sodium intake?

Output: anion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with sodium intake?. ### Response: anion.


Instruction: What is required to determine if relationships of sodium intake with BP are influenced by the accompanying anion?

Output: Future research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required to determine if relationships of sodium intake with BP are influenced by the accompanying anion?. ### Response: Future research.


Instruction: In the general population, what has been demonstrated to lower BP?

Output: potassium-containing salt sub-stitutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the general population, what has been demonstrated to lower BP?. ### Response: potassium-containing salt sub-stitutes.


Instruction: Why have people with CKD been excluded from clinical trialsevaluating potassium-based salt substitutes?

Output: lower BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why have people with CKD been excluded from clinical trialsevaluating potassium-based salt substitutes?. ### Response: lower BP.


Instruction: What is associated with higher potassium intake?

Output: higher risk of CKD progression and CV disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with higher potassium intake?. ### Response: higher risk of CKD progression and CV disease.


Instruction: What may have healthbenefits or unique risks when applied to CKD populations?

Output: potassium-containing salt substitutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have healthbenefits or unique risks when applied to CKD populations?. ### Response: potassium-containing salt substitutes.


Instruction: People of what ancestry are disproportionately repre-sented inCKD?

Output: African

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People of what ancestry are disproportionately repre-sented inCKD?. ### Response: African.


Instruction: Prior systematic reviews sug-gest that reductions in sodium intake may result in larger reduction in what?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prior systematic reviews sug-gest that reductions in sodium intake may result in larger reduction in what?. ### Response: BP.


Instruction: What are CKD patients of African and Asian ancestry compared to?

Output: Caucasians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are CKD patients of African and Asian ancestry compared to?. ### Response: Caucasians.


Instruction: What is uncertain andshould be evaluated in future studies?

Output: Whether such racial differencescan also be found in CKD populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uncertain andshould be evaluated in future studies?. ### Response: Whether such racial differencescan also be found in CKD populations.


Instruction: What is needed to tailor physical activity intensity and supervision to individual CKD patients?

Output: Identi ﬁcation of thesefactors and algorithms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to tailor physical activity intensity and supervision to individual CKD patients?. ### Response: Identi ﬁcation of thesefactors and algorithms.


Instruction: What is added to salt in some countries?

Output: Iodine supplements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is added to salt in some countries?. ### Response: Iodine supplements.


Instruction: What is needed to determine if restrictingsodium intake in CKD populations may contribute to toiodine deficiency?

Output: Future studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to determine if restrictingsodium intake in CKD populations may contribute to toiodine deficiency?. ### Response: Future studies.


Instruction: What is the name of the study that compares angioplasty and surgery for multivessel coronary artery disease?

Output: EAST trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares angioplasty and surgery for multivessel coronary artery disease?. ### Response: EAST trial.


Instruction: What are the results of the Emory Angioplasty versus Surgery Trial Inves-tigators?

Output: comparison of eligible registryand randomized patients in the EAST trial and influence of treatmentselection on outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the Emory Angioplasty versus Surgery Trial Inves-tigators?. ### Response: comparison of eligible registryand randomized patients in the EAST trial and influence of treatmentselection on outcomes.


Instruction: What is the name of the predictive accuracies ofSYNTAX score for predicting long-term outcomes of unprotected leftmain coronary artery revascularization?

Output: Validation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the predictive accuracies ofSYNTAX score for predicting long-term outcomes of unprotected leftmain coronary artery revascularization?. ### Response: Validation.


Instruction: What year did Am J Cardiol. 2011:107:360-6.954?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Am J Cardiol. 2011:107:360-6.954?. ### Response: 1997.


Instruction: What does SYNTAX stand for?

Output: Synergybetween PCI with Taxus and Cardiac Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SYNTAX stand for?. ### Response: Synergybetween PCI with Taxus and Cardiac Surgery.


Instruction: What are the two national databases used for quality improvement in cardiac surgery?

Output: VeteransAffairs and Society of Thoracic Surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two national databases used for quality improvement in cardiac surgery?. ### Response: VeteransAffairs and Society of Thoracic Surgeons.


Instruction: What is the prediction of outcomes after unprotected left main coronary revascularization?

Output: SYNTAX score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prediction of outcomes after unprotected left main coronary revascularization?. ### Response: SYNTAX score.


Instruction: What was the J AmColl Cardiol Intv. 2010:3:612–23.956?

Output: Validation of SYNTAX (Synergybetween PCI with Taxus and Cardiac Surgery) score for prediction ofoutcomes after unprotected left main coronary revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J AmColl Cardiol Intv. 2010:3:612–23.956?. ### Response: Validation of SYNTAX (Synergybetween PCI with Taxus and Cardiac Surgery) score for prediction ofoutcomes after unprotected left main coronary revascularization.


Instruction: Who published 2008 cardiac surgery risk models: part —coronary arterybypass grafting surgery?

Output: The Society of ThoracicSurgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published 2008 cardiac surgery risk models: part —coronary arterybypass grafting surgery?. ### Response: The Society of ThoracicSurgeons.


Instruction: What is the association of hospitalcoronary artery bypass volume with processes of care, mortality, mor-bidity and the Society of Thoracic Surgeons composite quality score?

Output: J Thorac Cardiovasc Surg. 2010;139:273–82.958

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of hospitalcoronary artery bypass volume with processes of care, mortality, mor-bidity and the Society of Thoracic Surgeons composite quality score?. ### Response: J Thorac Cardiovasc Surg. 2010;139:273–82.958.


Instruction: What is Buszman PE, Kiesz SR, Bochenek A, et al.?

Output: Acute and late outcomes ofunprotected left main stenting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Buszman PE, Kiesz SR, Bochenek A, et al.?. ### Response: Acute and late outcomes ofunprotected left main stenting.


Instruction: What are the outcomes of left main stenting in comparison to surgical revascularization?

Output: Acute and late

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes of left main stenting in comparison to surgical revascularization?. ### Response: Acute and late.


Instruction: What is the J Am Coll Cardiol. 2008?

Output: 51:538–45.959

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2008?. ### Response: 51:538–45.959.


Instruction: How many patients with multivessel coronary artery disease had long-term survival in the era of stetting?

Output: 11 661

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with multivessel coronary artery disease had long-term survival in the era of stetting?. ### Response: 11 661.


Instruction: What was the name of the report from the Alberta Provincial Project for Outcome Assessmentin Coronary Heart Disease Investigators?

Output: APPROACH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the report from the Alberta Provincial Project for Outcome Assessmentin Coronary Heart Disease Investigators?. ### Response: APPROACH.


Instruction: When did Takaro T, Hultgren HN, Lipton MJ, et al. do the VA cooperative ran-domized study of surgery for coronary arterial occlusive disease II.Subgroup with significant left main lesions?

Output: 1976

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Takaro T, Hultgren HN, Lipton MJ, et al. do the VA cooperative ran-domized study of surgery for coronary arterial occlusive disease II.Subgroup with significant left main lesions?. ### Response: 1976.


Instruction: What type of lesions are found in patients with left main coronary artery disease?

Output: Asymptomatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of lesions are found in patients with left main coronary artery disease?. ### Response: Asymptomatic.


Instruction: What is the name of the study done by the Veterans Administration for Coronary Arterial Occlusive Disease?

Output: Coop-erative Study of Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study done by the Veterans Administration for Coronary Arterial Occlusive Disease?. ### Response: Coop-erative Study of Surgery.


Instruction: In what year was Circulation published?

Output: 1976

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was Circulation published?. ### Response: 1976.


Instruction: What is the acronym for the Coronary Artery Surgery Study?

Output: CASS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Coronary Artery Surgery Study?. ### Response: CASS.


Instruction: When was the Circulation 79:1171–9.963 published?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation 79:1171–9.963 published?. ### Response: 1989.


Instruction: What does Global Risk Classification and Clinical SYNTAX stand for?

Output: Synergy between Percutaneous Coronar yIntervention with TAXUS and Cardiac Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Global Risk Classification and Clinical SYNTAX stand for?. ### Response: Synergy between Percutaneous Coronar yIntervention with TAXUS and Cardiac Surgery.


Instruction: What is the Surgical Score in Patients Undergoing Percutaneous or Surgical Left Main Revascularization?

Output: Global Risk Classificationand Clinical SYNTAX (Synergy between Percutaneous Coronar yIntervention with TAXUS and Cardiac Surgery) Score in PatientsUndergoing Percutaneous or Surgical Left Main Revascularization.J Am Coll Cardiol Intv. 2011;4:287–97.964

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Surgical Score in Patients Undergoing Percutaneous or Surgical Left Main Revascularization?. ### Response: Global Risk Classificationand Clinical SYNTAX (Synergy between Percutaneous Coronar yIntervention with TAXUS and Cardiac Surgery) Score in PatientsUndergoing Percutaneous or Surgical Left Main Revascularization.J Am Coll Cardiol Intv. 2011;4:287–97.964.


Instruction: What was the J Am Coll Cardiol Intv. 2011;4:287–97.964?

Output: Global Risk Classificationand Clinical SYNTAX (Synergy between Percutaneous Coronar yIntervention with TAXUS and Cardiac Surgery) Score in PatientsUndergoing Percutaneous or Surgical Left Main Revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol Intv. 2011;4:287–97.964?. ### Response: Global Risk Classificationand Clinical SYNTAX (Synergy between Percutaneous Coronar yIntervention with TAXUS and Cardiac Surgery) Score in PatientsUndergoing Percutaneous or Surgical Left Main Revascularization.


Instruction: What is the Grade Quality of evidence Meaning?

Output: A High

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Grade Quality of evidence Meaning?. ### Response: A High.


Instruction: How are we confident that the true effect lies close to that of the estimate of the effect?

Output: High

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are we confident that the true effect lies close to that of the estimate of the effect?. ### Response: High.


Instruction: What is a possibility that it is substantially different?

Output: The recommendation is likely to requiresubstantial debate and involvement ofstakeholders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possibility that it is substantially different?. ### Response: The recommendation is likely to requiresubstantial debate and involvement ofstakeholders.


Instruction: What is a possibility that it is substantially different from the estimate of the effect?

Output: The recommendation is likely to requiresubstantial debate and involvement ofstakeholders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possibility that it is substantially different from the estimate of the effect?. ### Response: The recommendation is likely to requiresubstantial debate and involvement ofstakeholders.


Instruction: What is very low The estimate of effect is very uncertain and often will be far from the truth?

Output: D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is very low The estimate of effect is very uncertain and often will be far from the truth?. ### Response: D.


Instruction: How many people in your situation would want the recommended course of action?

Output: Most

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people in your situation would want the recommended course of action?. ### Response: Most.


Instruction: What should most patients receive?

Output: therecommended course of action

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should most patients receive?. ### Response: therecommended course of action.


Instruction: The recommendation can be evaluated as what?

Output: acandidate for developing a policy or aperformance measure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The recommendation can be evaluated as what?. ### Response: acandidate for developing a policy or aperformance measure.


Instruction: How many people in your situation would want the recommended course ofaction but many would not?

Output: The majority

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people in your situation would want the recommended course ofaction but many would not?. ### Response: The majority.


Instruction: Each patient needs help to arrive at a management decision consistent with her or his values and preferences?

Output: Level 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Each patient needs help to arrive at a management decision consistent with her or his values and preferences?. ### Response: Level 2.


Instruction: What is likely to requiresubstantial debate and involvement ofstakeholders before policy can be determined?

Output: The recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to requiresubstantial debate and involvement ofstakeholders before policy can be determined?. ### Response: The recommendation.


Instruction: What category was used to provide guidance based on common sense or where the topic does not allow adequate application of evidence?

Output: Not Graded

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What category was used to provide guidance based on common sense or where the topic does not allow adequate application of evidence?. ### Response: Not Graded.


Instruction: What are recommendations regarding monitoring intervals, counseling, and referral to other clinical specialists?

Output: The most common examples

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are recommendations regarding monitoring intervals, counseling, and referral to other clinical specialists?. ### Response: The most common examples.


Instruction: The ung raded recommendations are generally written as what?

Output: simple declarative statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ung raded recommendations are generally written as what?. ### Response: simple declarative statements.


Instruction: What is the strength of a recommendation indicated as in each recommendation?

Output: Level 1 ,Level 2 ,o rNot Graded ,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strength of a recommendation indicated as in each recommendation?. ### Response: Level 1 ,Level 2 ,o rNot Graded ,.


Instruction: What is shown as A,B,C,orD?

Output: the quality of thesupporting evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shown as A,B,C,orD?. ### Response: the quality of thesupporting evidence.


Instruction: Powers et al 2019 Guidelines for Management of AIS e411 276.

Output: Liu L, Xiong XY , Zhang Q, Fan XT, Yang QW. The efficacy of prophy-lactic antibiotics on post-stroke infections: an updated systematic review and meta-analysis. Sci Rep. 2016;6:36656. doi: 10.1038/srep36656 277. Zheng F, Spreckelsen NV , Zhang X, Stavrinou P, Timmer M, Dohmen C, Goldbrunner R, Cao F, Zhang Q, Ran Q, et al. Should preventive antibiot-ics be used in patients with acute stroke? A systematic review and meta-analysis of randomized controlled trials. PLoS One. 2017;12:e0186607

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Powers et al 2019 Guidelines for Management of AIS e411 276.. ### Response: Liu L, Xiong XY , Zhang Q, Fan XT, Yang QW. The efficacy of prophy-lactic antibiotics on post-stroke infections: an updated systematic review and meta-analysis. Sci Rep. 2016;6:36656. doi: 10.1038/srep36656 277. Zheng F, Spreckelsen NV , Zhang X, Stavrinou P, Timmer M, Dohmen C, Goldbrunner R, Cao F, Zhang Q, Ran Q, et al. Should preventive antibiot-ics be used in patients with acute stroke? A systematic review and meta-analysis of randomized controlled trials. PLoS One. 2017;12:e0186607.


Instruction: Liu L, Xiong XY, Zhang Q, Fan XT, Yang QW. The efficacy of prophylactic antibiotics on post stroke infections: an updated systematic review and meta-analysis. Sci Rep. 2016;6:36656.

Output: Powers et al  2019 Guidelines for Management of AIS  e411 276. Liu L, Xiong XY , Zhang Q, Fan XT, Yang QW. The efficacy of prophy-lactic antibiotics on post-stroke infections: an updated systematic review and meta-analysis. Sci Rep. 2016;6:36656. doi: 10.1038/srep36656 277

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Liu L, Xiong XY, Zhang Q, Fan XT, Yang QW. The efficacy of prophylactic antibiotics on post stroke infections: an updated systematic review and meta-analysis. Sci Rep. 2016;6:36656.. ### Response: Powers et al  2019 Guidelines for Management of AIS  e411 276. Liu L, Xiong XY , Zhang Q, Fan XT, Yang QW. The efficacy of prophy-lactic antibiotics on post-stroke infections: an updated systematic review and meta-analysis. Sci Rep. 2016;6:36656. doi: 10.1038/srep36656 277.


Instruction: What is the name of the systematic review and meta-analysis of randomized controlled trials?

Output: PLoS One

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis of randomized controlled trials?. ### Response: PLoS One.


Instruction: What should preventive antibiotics be used in patients with acute stroke?

Output: antibiot-ics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should preventive antibiotics be used in patients with acute stroke?. ### Response: antibiot-ics.


Instruction: What is the name of the journal that publishes a meta-analysis of randomized controlled trials?

Output: PLoS One

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that publishes a meta-analysis of randomized controlled trials?. ### Response: PLoS One.


Instruction: What does PLoS One do?

Output: preventing infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PLoS One do?. ### Response: preventing infections.


Instruction: Who is a VERT Trial Collaboration Group member?

Output: Bernhardt J, Langhorne P, Lindley RI, Thrift AG, Ellery F, Collier J, Churilov L, Moodie M, Dewey H, Donnan G

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a VERT Trial Collaboration Group member?. ### Response: Bernhardt J, Langhorne P, Lindley RI, Thrift AG, Ellery F, Collier J, Churilov L, Moodie M, Dewey H, Donnan G.


Instruction: What is the name of the randomised controlled trial that evaluated the safety and efficacy of very early mobilisation within 24 h of stroke onset?

Output: A VERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial that evaluated the safety and efficacy of very early mobilisation within 24 h of stroke onset?. ### Response: A VERT.


Instruction: What is a VERT?

Output: a randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a VERT?. ### Response: a randomised controlled trial.


Instruction: What is the name of the randomised controlled trial?

Output: A VERT Trial Collaboration Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial?. ### Response: A VERT Trial Collaboration Group.


Instruction: What is a term for cerebral apoplexy?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for cerebral apoplexy?. ### Response: stroke.


Instruction: What is the term for a stroke treated with or without prolonged treatment?

Output: Cerebral apoplexy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for a stroke treated with or without prolonged treatment?. ### Response: Cerebral apoplexy.


Instruction: What is cerebral apoplexy treated with or without prolonged artificial hyperventilation?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cerebral apoplexy treated with or without prolonged artificial hyperventilation?. ### Response: stroke.


Instruction: What is the cause of death of stroke?

Output: Cerebral apoplexy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of death of stroke?. ### Response: Cerebral apoplexy.


Instruction: When was the 4th issue of Stroke published?

Output: 1973

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 4th issue of Stroke published?. ### Response: 1973.


Instruction: How many people died from stroke in 1973?

Output: 568–631. doi: 10.1161/01.str.4.4.568 282

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people died from stroke in 1973?. ### Response: 568–631. doi: 10.1161/01.str.4.4.568 282.


Instruction: What can hyperventilation cause in severe head injury?

Output: Adverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can hyperventilation cause in severe head injury?. ### Response: Adverse effects.


Instruction: What is the name of the journal that studies cerebral hemodynamic changes during sustained hypocapnia?

Output: Acta Neurochir Suppl

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies cerebral hemodynamic changes during sustained hypocapnia?. ### Response: Acta Neurochir Suppl.


Instruction: How long did brain trauma time-course of cere-bral blood flow velocity and intracranial pressure last?

Output: 284

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did brain trauma time-course of cere-bral blood flow velocity and intracranial pressure last?. ### Response: 284.


Instruction: What is the name of the study that showed moderate reductions in arterial CO2 after brain trauma?

Output: Intensive Care Med.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that showed moderate reductions in arterial CO2 after brain trauma?. ### Response: Intensive Care Med..


Instruction: What changes in cerebral compartmental compliances during mild hypocapnia in patients with traumatic brain injury?

Output: Changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What changes in cerebral compartmental compliances during mild hypocapnia in patients with traumatic brain injury?. ### Response: Changes.


Instruction: What is the doi: 10.1089/neu.2010.1377 285.

Output: J Neurotrauma

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1089/neu.2010.1377 285.. ### Response: J Neurotrauma.


Instruction: What are the adverse effects of prolonged hyperventilation?

Output: cerebral circu-lation, clinical course, and cause of death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the adverse effects of prolonged hyperventilation?. ### Response: cerebral circu-lation, clinical course, and cause of death.


Instruction: What does prolonged hyperventilation do in patients with severe head injury?

Output: Adverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does prolonged hyperventilation do in patients with severe head injury?. ### Response: Adverse effects.


Instruction: What is the name of the randomized clinical trial?

Output: A VERT Trial Collaboration Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial?. ### Response: A VERT Trial Collaboration Group.


Instruction: When was the J Neurosurg.75:731-739?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Neurosurg.75:731-739?. ### Response: 1991.


Instruction: What year did AACVPR/ACC/AHA publish per-formance measures on cardiac rehabilitation for referral to and delivery of cardiac rehabilitation/secondary prevention services?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did AACVPR/ACC/AHA publish per-formance measures on cardiac rehabilitation for referral to and delivery of cardiac rehabilitation/secondary prevention services?. ### Response: 2007.


Instruction: What does regular exercise training compare to percutaneous intervention?

Output: reduction of inflam-matory markers and cardiovascular events in patients with coronaryartery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does regular exercise training compare to percutaneous intervention?. ### Response: reduction of inflam-matory markers and cardiovascular events in patients with coronaryartery disease.


Instruction: What does AHA/ACC secondary prevention and risk reduction therapy for patients with coronary andother atherosclerotic vascular disease do?

Output: a guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AHA/ACC secondary prevention and risk reduction therapy for patients with coronary andother atherosclerotic vascular disease do?. ### Response: a guideline.


Instruction: What is the acronym for atherosclerotic vascular disease?

Output: AHA/ACC secondaryprevention and risk reduction therapy for patients with coronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for atherosclerotic vascular disease?. ### Response: AHA/ACC secondaryprevention and risk reduction therapy for patients with coronary.


Instruction: When was the 2011 update published?

Output: November 3,2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2011 update published?. ### Response: November 3,2011.


Instruction: What was the name of the third report of the NCEP?

Output: Adult Treatment Panel III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the third report of the NCEP?. ### Response: Adult Treatment Panel III.


Instruction: What is the final report on Detection, Evaluation, and Treatment of High BloodCholesterol in Adults called?

Output: Adult Treatment Panel III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the final report on Detection, Evaluation, and Treatment of High BloodCholesterol in Adults called?. ### Response: Adult Treatment Panel III.


Instruction: When did Circu-lation issue 106:3143–421.807?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circu-lation issue 106:3143–421.807?. ### Response: 2002.


Instruction: What does weight reduction have on bloodlipids and lipoproteins?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does weight reduction have on bloodlipids and lipoproteins?. ### Response: Effects.


Instruction: How many people participated in a meta-analysis of data on the efficacy and safety of moreintensive lowering of LDL cholesterol?

Output: 170 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people participated in a meta-analysis of data on the efficacy and safety of moreintensive lowering of LDL cholesterol?. ### Response: 170 000.


Instruction: When did the IDEAL study begin?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the IDEAL study begin?. ### Response: 2004.


Instruction: What is the name of the randomized controlled trial?

Output: IDEAL study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial?. ### Response: IDEAL study.


Instruction: What is a secondary prevention after myocardialinfarction?

Output: High-dose atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a secondary prevention after myocardialinfarction?. ### Response: High-dose atorvastatin.


Instruction: When was the IDEAL study conducted?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the IDEAL study conducted?. ### Response: 2005.


Instruction: How many participants participated in a meta-analysis of data from 26 randomised trials?

Output: 170 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants participated in a meta-analysis of data from 26 randomised trials?. ### Response: 170 000.


Instruction: What is the name of the study that evaluated the efficacy and safety of more intensive lowering of LDL cholesterol?

Output: CTT) Collaboration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the efficacy and safety of more intensive lowering of LDL cholesterol?. ### Response: CTT) Collaboration.


Instruction: When was the Lancet 376:1670–81.811 published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet 376:1670–81.811 published?. ### Response: 2010.


Instruction: What is the difference between statin and statin therapy?

Output: intensive versus moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between statin and statin therapy?. ### Response: intensive versus moderate.


Instruction: What are the implications of recent clinicaltrials for the National Cholesterol Education Program Adult TreatmentPanel III guidelines?

Output: 110:227–39.813

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the implications of recent clinicaltrials for the National Cholesterol Education Program Adult TreatmentPanel III guidelines?. ### Response: 110:227–39.813.


Instruction: What is the 7th report of the JointNational Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure?

Output: Seventh

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 7th report of the JointNational Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure?. ### Response: Seventh.


Instruction: What was the name of the seventh report?

Output: JointNational Committee on Prevention, Detection, Evaluation, andTreatment of High Blood Pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the seventh report?. ### Response: JointNational Committee on Prevention, Detection, Evaluation, andTreatment of High Blood Pressure.


Instruction: Appel LJ, Frohlich ED, Hall JE, et al. The importance of what?

Output: aerobic exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Appel LJ, Frohlich ED, Hall JE, et al. The importance of what?. ### Response: aerobic exercise.


Instruction: What is the leading cause of death for people of most racial/ethnic groups in the US?

Output: S1-1–S1-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the leading cause of death for people of most racial/ethnic groups in the US?. ### Response: S1-1–S1-3.


Instruction: How much money is estimated to be spent annually on healthcare services, medications, and lost productivity?

Output: >$200 billion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much money is estimated to be spent annually on healthcare services, medications, and lost productivity?. ### Response: >$200 billion.


Instruction: What is at-tributable to suboptimal implementation of preven-tion strategies and uncontrolled ASCVD risk factors?

Output: S1-1–S1-3 In the United States, it is also the leading cause of death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is at-tributable to suboptimal implementation of preven-tion strategies and uncontrolled ASCVD risk factors?. ### Response: S1-1–S1-3 In the United States, it is also the leading cause of death.


Instruction: What is the term for a myocardial infarc-tion?

Output: MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for a myocardial infarc-tion?. ### Response: MI.


Instruction: How many cardiovas-cular risk factors did most Americans have before their ASCVD event?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cardiovas-cular risk factors did most Americans have before their ASCVD event?. ### Response: 1.


Instruction: In 2010, what was the AHA's definition of "ideal cardiovascular health"?

Output: Life’s Simple 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 2010, what was the AHA's definition of "ideal cardiovascular health"?. ### Response: Life’s Simple 7.


Instruction: What is a new model of ideal cardiovascular health called?

Output: Life’s Simple 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new model of ideal cardiovascular health called?. ### Response: Life’s Simple 7.


Instruction: What is the 2018 Journal of American College of Cardiol-ogy (JACC) Cardiovascular Health Promotion Series?

Output: Clinicians will find the 2018 Journal of American College of Cardiol-ogy (JACC) Cardiovascular Health Promotion Series very helpful in approaching the various aspects of preven-tion with patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 Journal of American College of Cardiol-ogy (JACC) Cardiovascular Health Promotion Series?. ### Response: Clinicians will find the 2018 Journal of American College of Cardiol-ogy (JACC) Cardiovascular Health Promotion Series very helpful in approaching the various aspects of preven-tion with patients.


Instruction: What has been associated with a lower prevalence and incidence of ASCVD events, heart failure, atrial fibrillation, cancer, depression and cognitive impairment?

Output: ideal cardiovascular health factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been associated with a lower prevalence and incidence of ASCVD events, heart failure, atrial fibrillation, cancer, depression and cognitive impairment?. ### Response: ideal cardiovascular health factors.


Instruction: What is critically important for prevention of many important health conditions?

Output: moving individuals toward ideal cardiovascular health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is critically important for prevention of many important health conditions?. ### Response: moving individuals toward ideal cardiovascular health.


Instruction: The ACC/AHA Task Force on Clinical Practice Guide-lines has commissioned a guideline to consolidate what?

Output: existing recommendations and various recent scientific statements, expert consensus documents, and clinical practice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ACC/AHA Task Force on Clinical Practice Guide-lines has commissioned a guideline to consolidate what?. ### Response: existing recommendations and various recent scientific statements, expert consensus documents, and clinical practice guidelines.


Instruction: What is the primary prevention of ASCVD?

Output: promote a healthy lifestyle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention of ASCVD?. ### Response: promote a healthy lifestyle.


Instruction: What are new recom-mendations for aspirin use, exercise and physical activ-ity, and tobacco use?

Output: recommendations related to team-based care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are new recom-mendations for aspirin use, exercise and physical activ-ity, and tobacco use?. ### Response: recommendations related to team-based care.


Instruction: To create a comprehensive yet targeted ACC/AHA guideline on the prevention of asCVD, what is the goal of the guideline?

Output: to consolidate existing recommendations and various recent scientific statements, expert consensus documents, and clinical practice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To create a comprehensive yet targeted ACC/AHA guideline on the prevention of asCVD, what is the goal of the guideline?. ### Response: to consolidate existing recommendations and various recent scientific statements, expert consensus documents, and clinical practice guidelines.


Instruction: What is the purpose of the ACC/AHA guideline?

Output: to consolidate existing recommendations and various recent scientific statements, expert consensus documents, and clinical practice guidelines into a single guidance document fo-cused on the primary prevention of ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of the ACC/AHA guideline?. ### Response: to consolidate existing recommendations and various recent scientific statements, expert consensus documents, and clinical practice guidelines into a single guidance document fo-cused on the primary prevention of ASCVD.


Instruction: What format has the guideline been formatted in?

Output: modular chunk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What format has the guideline been formatted in?. ### Response: modular chunk.


Instruction: Where do prevention strategies occur?

Output: at the population level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where do prevention strategies occur?. ### Response: at the population level.


Instruction: Who must engage with prevention strategies?

Output: individual adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who must engage with prevention strategies?. ### Response: individual adults.


Instruction: How can adults slow the de-velopment of ASCVD?

Output: engage individual adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can adults slow the de-velopment of ASCVD?. ### Response: engage individual adults.


Instruction: What is the most important way to pre-vent asscvd?

Output: to promote a healthy lifestyle through-out life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most important way to pre-vent asscvd?. ### Response: to promote a healthy lifestyle through-out life.


Instruction: How must prevention strategies include a strong focus on lifestyle optimization?

Output: to minimize the risk of future ASCVD events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How must prevention strategies include a strong focus on lifestyle optimization?. ### Response: to minimize the risk of future ASCVD events.


Instruction: Tobacco use and ex-posure to secondhand smoke) to minimize the risk of future ASCVD events?

Output: Prevention strategies must include a strong focus on lifestyle optimization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tobacco use and ex-posure to secondhand smoke) to minimize the risk of future ASCVD events?. ### Response: Prevention strategies must include a strong focus on lifestyle optimization.


Instruction: What is the first step in deciding where there may be a need for pharmacotherapy?

Output: A comprehensive patient-centered approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first step in deciding where there may be a need for pharmacotherapy?. ### Response: A comprehensive patient-centered approach.


Instruction: A comprehensive patient-centered approach addresses all aspects of what?

Output: preven-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A comprehensive patient-centered approach addresses all aspects of what?. ### Response: preven-tion.


Instruction: What should be emphasized on a regular basis?

Output: lifestyle goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be emphasized on a regular basis?. ### Response: lifestyle goals.


Instruction: When should medications to reduce ASCVD risk be considered?

Output: when a person’s risk is sufficiently high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should medications to reduce ASCVD risk be considered?. ### Response: when a person’s risk is sufficiently high.


Instruction: What should medications to reduce ASCVD risk be considered as part of?

Output: shared

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should medications to reduce ASCVD risk be considered as part of?. ### Response: shared.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227?. ### Response: Otto et al.


Instruction: How long has Arcidi JM Jr, Rodriguez E, Elbeery JR, et al. had experience with minimally invasive approach for reoperations involving the mitral valve?

Output: Fifteen-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has Arcidi JM Jr, Rodriguez E, Elbeery JR, et al. had experience with minimally invasive approach for reoperations involving the mitral valve?. ### Response: Fifteen-year.


Instruction: How many operations were performed from a single high-volume center?

Output: 3895

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many operations were performed from a single high-volume center?. ### Response: 3895.


Instruction: How many procedures were performed?

Output: 3895

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many procedures were performed?. ### Response: 3895.


Instruction: What is the name of the procedure performed to learn minimally invasive mitral valve surgery?

Output: a cumulative sum sequential probability analy-sis of 3895 operations from a single high-volume center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure performed to learn minimally invasive mitral valve surgery?. ### Response: a cumulative sum sequential probability analy-sis of 3895 operations from a single high-volume center.


Instruction: What year did Circulation. 2013:128:483–91?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circulation. 2013:128:483–91?. ### Response: 2013.


Instruction: What is the difference between robotic and conventional approaches for repair of posterior mitral valve prolapse?

Output: potential realized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between robotic and conventional approaches for repair of posterior mitral valve prolapse?. ### Response: potential realized.


Instruction: When did Robotic repair for all prolapse subsets use techniques identical to open technique?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Robotic repair for all prolapse subsets use techniques identical to open technique?. ### Response: 2011.


Instruction: What is the benchmark against which percutaneous interventions should be judged?

Output: Robotic mitral valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benchmark against which percutaneous interventions should be judged?. ### Response: Robotic mitral valve repair.


Instruction: What is a propensity score analysis of early outcomes of throacoscopic versus open mitral valve repair?

Output: 38. Suri RM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a propensity score analysis of early outcomes of throacoscopic versus open mitral valve repair?. ### Response: 38. Suri RM.


Instruction: What is a propensity score analysis of early outcomes of mitral valve repair?

Output: Thoracoscopic versus open mitral valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a propensity score analysis of early outcomes of mitral valve repair?. ### Response: Thoracoscopic versus open mitral valve repair.


Instruction: What is the name of the study that analyzed early outcomes?

Output: Thoracoscopic versus open mitral valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that analyzed early outcomes?. ### Response: Thoracoscopic versus open mitral valve repair.


Instruction: How many years did it take to repair a valve for mitral regurgitation?

Output: 22

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years did it take to repair a valve for mitral regurgitation?. ### Response: 22.


Instruction: What are the long-term results of mitral valve repair for?

Output: regurgitation due to leaflet prolapse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the long-term results of mitral valve repair for?. ### Response: regurgitation due to leaflet prolapse.


Instruction: What is the fallacy of “normal” preoperative myocardial func-tion?

Output: Left ventricular dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the fallacy of “normal” preoperative myocardial func-tion?. ### Response: Left ventricular dysfunction.


Instruction: How did Quintana E, Suri RM, Thalji NM, et al. view left ventricular dysfunction?

Output: the fallacy of “normal” preoperative myocardial func-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Quintana E, Suri RM, Thalji NM, et al. view left ventricular dysfunction?. ### Response: the fallacy of “normal” preoperative myocardial func-tion.


Instruction: What is the name of the registry report for transcatheter mitral valve repair in the U.S.?

Output: STS/ACC TVT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry report for transcatheter mitral valve repair in the U.S.?. ### Response: STS/ACC TVT.


Instruction: What is a typical preoperative myocardial function?

Output: Left ventricular dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a typical preoperative myocardial function?. ### Response: Left ventricular dysfunction.


Instruction: Who is the author of the STS/ACC TVT registry?

Output: Sorajja P , Vemulapalli S, Feldman T

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the STS/ACC TVT registry?. ### Response: Sorajja P , Vemulapalli S, Feldman T.


Instruction: What are the clinical results of the rheumatic mitral valve re-pair?

Output: 22-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinical results of the rheumatic mitral valve re-pair?. ### Response: 22-year.


Instruction: What is the name of the study that examined the clinical outcomes of the mitral regurgitation severity?

Output: prospective multicenter trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the clinical outcomes of the mitral regurgitation severity?. ### Response: prospective multicenter trial.


Instruction: How long did it take to complete the repair?

Output: 22-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to complete the repair?. ### Response: 22-year.


Instruction: What did Grayburn PA, Carabello B, Hung J, et al. Defining “severe” secondary mi-tral regurgitation: emphasizing an integrated approach?

Output: J Am Coll Cardiol. 2014;64:2792–801

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Grayburn PA, Carabello B, Hung J, et al. Defining “severe” secondary mi-tral regurgitation: emphasizing an integrated approach?. ### Response: J Am Coll Cardiol. 2014;64:2792–801.


Instruction: What is the name of the procedure used for severe ischemic mitral regurgitation?

Output: Mitral-valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used for severe ischemic mitral regurgitation?. ### Response: Mitral-valve repair.


Instruction: How long does it take to treat severe ischemia with a sur-gical treatment?

Output: Two-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to treat severe ischemia with a sur-gical treatment?. ### Response: Two-year.


Instruction: What is one of the outcomes of the sur gical therapy?

Output: Two-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the outcomes of the sur gical therapy?. ### Response: Two-year.


Instruction: What is the diagnostic value of advanced imaging mo-dalities for the detection of mitral annuloplasty ring and prosthetic valve dehiscence?

Output: 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diagnostic value of advanced imaging mo-dalities for the detection of mitral annuloplasty ring and prosthetic valve dehiscence?. ### Response: 7.


Instruction: What is real-time 3-dimensional trans-esophageal echocardiography for?

Output: evaluation of post-operative mitral annuloplasty ring and prosthetic valve dehiscence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is real-time 3-dimensional trans-esophageal echocardiography for?. ### Response: evaluation of post-operative mitral annuloplasty ring and prosthetic valve dehiscence.


Instruction: What is the diagnostic value of advanced imaging mo-dalities for the detection and differentiation of prosthetic valve obstruction?

Output: 8. Kim JY, Suh YJ, Han K, et al. Diagnostic value of advanced imaging mo-dalities for the detection and differentiation of prosthetic valve obstruc-tion: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diagnostic value of advanced imaging mo-dalities for the detection and differentiation of prosthetic valve obstruction?. ### Response: 8. Kim JY, Suh YJ, Han K, et al. Diagnostic value of advanced imaging mo-dalities for the detection and differentiation of prosthetic valve obstruc-tion: a systematic review and meta-analysis.


Instruction: When did JACC Cardiovasc Imaging issue 12:2182-92?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JACC Cardiovasc Imaging issue 12:2182-92?. ### Response: 2019.


Instruction: What was the name of the systematic review and meta-analysis?

Output: Diagnostic value of advanced imaging mo-dalities for the detection and differentiation of prosthetic valve obstruc-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic review and meta-analysis?. ### Response: Diagnostic value of advanced imaging mo-dalities for the detection and differentiation of prosthetic valve obstruc-tion.


Instruction: How was hemodynamic valve deterioration determined after bioprosthetic surgical aortic valve replacement?

Output: Rate, timing, correlates, and out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was hemodynamic valve deterioration determined after bioprosthetic surgical aortic valve replacement?. ### Response: Rate, timing, correlates, and out-comes.


Instruction: What causes hemodynamic valve deterioration after bioprosthetic surgical aortic valve replacement?

Output: struc-tural valve degeneration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes hemodynamic valve deterioration after bioprosthetic surgical aortic valve replacement?. ### Response: struc-tural valve degeneration.


Instruction: What is Rahimtoola SH's job title?

Output: 10. Rahimtoola SH. Choice of prosthetic heart valve in adults an update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Rahimtoola SH's job title?. ### Response: 10. Rahimtoola SH. Choice of prosthetic heart valve in adults an update.


Instruction: What is weighed against reoperation risk after aortic valve replacement?

Output: lifetime anticoagulant-related event risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is weighed against reoperation risk after aortic valve replacement?. ### Response: lifetime anticoagulant-related event risk.


Instruction: What is the risk of lifetime anticoagulant-related event?

Output: reopera-tion risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of lifetime anticoagulant-related event?. ### Response: reopera-tion risk.


Instruction: When was the J Thorac Cardiovasc Surg. 137:881–6, 866.e1–5?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg. 137:881–6, 866.e1–5?. ### Response: 2009.


Instruction: What is the standard definition of struc-tural valve degeneration for surgical and transcatheter bioprosthetic aortic valves?

Output: Standardized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the standard definition of struc-tural valve degeneration for surgical and transcatheter bioprosthetic aortic valves?. ### Response: Standardized.


Instruction: What does Douglas PS, Leon MB, Mack MJ, et al. study?

Output: Longitudinal hemodynamics of transcatheter and surgical aortic valves in the PARTNER trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Douglas PS, Leon MB, Mack MJ, et al. study?. ### Response: Longitudinal hemodynamics of transcatheter and surgical aortic valves in the PARTNER trial.


Instruction: How long did the PARTNER trial last?

Output: 5-Year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the PARTNER trial last?. ### Response: 5-Year.


Instruction: What is the name of the study that evaluated long-term outcomes of transcatheter and surgical aortic valve replacement?

Output: PARTNER trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated long-term outcomes of transcatheter and surgical aortic valve replacement?. ### Response: PARTNER trial.


Instruction: What is the name of the randomised controlled trial for high surgical risk patients with aortic stenosis?

Output: PARTNER 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial for high surgical risk patients with aortic stenosis?. ### Response: PARTNER 1.


Instruction: How long does it take to replace a transcatheter valve?

Output: 5-Year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to replace a transcatheter valve?. ### Response: 5-Year.


Instruction: What is PARTNER 1?

Output: a randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PARTNER 1?. ### Response: a randomised controlled trial.


Instruction: What is stenosis?

Output: aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stenosis?. ### Response: aortic stenosis.


Instruction: What is the name of the randomised controlled trial?

Output: PARTNER 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial?. ### Response: PARTNER 1.


Instruction: When did the Lancet issue 385:2485-91?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet issue 385:2485-91?. ### Response: 2015.


Instruction: Who is the author of the study?

Output: Manoharan G

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study?. ### Response: Manoharan G.


Instruction: What is the name of the study that evaluated 1-Year outcomes with the Evolut R self-expanding transcatheter aortic valve?

Output: inter -national FORWARD study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated 1-Year outcomes with the Evolut R self-expanding transcatheter aortic valve?. ### Response: inter -national FORWARD study.


Instruction: When was the JACC Cardiovasc Interv. 2018 11:2326–34?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JACC Cardiovasc Interv. 2018 11:2326–34?. ### Response: April 28, 2023.


Instruction: How many consecutivepatients with permanent transvenous pacemakers were treated in 1975?

Output: Four hundred

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many consecutivepatients with permanent transvenous pacemakers were treated in 1975?. ### Response: Four hundred.


Instruction: What isoxazolyl penicillin used for?

Output: Pacemaker infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isoxazolyl penicillin used for?. ### Response: Pacemaker infections.


Instruction: When was the acta Med ScandSuppl published?

Output: 1985

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the acta Med ScandSuppl published?. ### Response: 1985.


Instruction: How many cases of pacemaker endocarditis were there in 1985?

Output: 44

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of pacemaker endocarditis were there in 1985?. ### Response: 44.


Instruction: What is the name of the disease that is the result of a review of the literature?

Output: Pacemaker endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that is the result of a review of the literature?. ### Response: Pacemaker endocarditis.


Instruction: When was the 73rd issue of Medicine published?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 73rd issue of Medicine published?. ### Response: 1994.


Instruction: What is the name of the implanted defibrillator used in human beings?

Output: pacemaker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the implanted defibrillator used in human beings?. ### Response: pacemaker.


Instruction: What does Reid PR, Mower MM, Watkins L, Schauble JF, Langer A, Heilman MS, Kolenik SA, Fischell RE, Weisfeldt ML do?

Output: Termination of malignant ventricular arrhythmias with an implantedautomatic defibrillator in human beings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Reid PR, Mower MM, Watkins L, Schauble JF, Langer A, Heilman MS, Kolenik SA, Fischell RE, Weisfeldt ML do?. ### Response: Termination of malignant ventricular arrhythmias with an implantedautomatic defibrillator in human beings.


Instruction: When did N Engl J Med issue 303:322-324?

Output: 1980

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 303:322-324?. ### Response: 1980.


Instruction: What are the long-term infection rates associated with with pectoralversusabdominal approach to cardioverter-defibrillator implants?

Output: 750–753.16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the long-term infection rates associated with with pectoralversusabdominal approach to cardioverter-defibrillator implants?. ### Response: 750–753.16.


Instruction: What is the name of the study that investigated the long term infection rates of cardiac device infections among Medicare beneficiaries?

Output: Am J Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the long term infection rates of cardiac device infections among Medicare beneficiaries?. ### Response: Am J Cardiol.


Instruction: How long did it take for Medicare beneficiaries to experience cardiac device infections?

Output: 1990–1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for Medicare beneficiaries to experience cardiac device infections?. ### Response: 1990–1999.


Instruction: What is the name of the study that examined permanent pacemaker and implantable cardioverter-defibrillator infection?

Output: population-basedstudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined permanent pacemaker and implantable cardioverter-defibrillator infection?. ### Response: population-basedstudy.


Instruction: What is the risk of infection from pacemaker or defi-brillator surgery?

Output: Renal insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of infection from pacemaker or defi-brillator surgery?. ### Response: Renal insufficiency.


Instruction: What is Bloom H, Heeke B, Leon A, Mera F, Delurgio D, Beshai J, Langberg J.Renal insufficiency and the risk?

Output: infection from pacemaker or defi-brillator surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Bloom H, Heeke B, Leon A, Mera F, Delurgio D, Beshai J, Langberg J.Renal insufficiency and the risk?. ### Response: infection from pacemaker or defi-brillator surgery.


Instruction: What are the risk factors and time delay?

Output: Reviewer DisclosuresReviewer Employment Research Grant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risk factors and time delay?. ### Response: Reviewer DisclosuresReviewer Employment Research Grant.


Instruction: What is the name of the company that is not a Boston Scientific company?

Output: Medtronic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the company that is not a Boston Scientific company?. ### Response: Medtronic.


Instruction: Boston Scientific*;Biotronik*;Spectranetics*;Cameron Health,Inc*; Medtronic*;LifeWatch*; StJude Medical*;Boston Scientific*);LifeWatchNone None None What University ofWashington is one of the few that has none of the above?

Output: Martin Burke University ofChicago

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Boston Scientific*;Biotronik*;Spectranetics*;Cameron Health,Inc*; Medtronic*;LifeWatch*; StJude Medical*;Boston Scientific*);LifeWatchNone None None What University ofWashington is one of the few that has none of the above?. ### Response: Martin Burke University ofChicago.


Instruction: What table represents the relationships of reviewers that may be perceived as actual or reasonably perceived conflicts of interest as reported on the Disclosure?

Output: This table

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What table represents the relationships of reviewers that may be perceived as actual or reasonably perceived conflicts of interest as reported on the Disclosure?. ### Response: This table.


Instruction: CCBs, inhibitors of RAS, and chlorthalidone comprise a common what?

Output: 3-drug regimen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CCBs, inhibitors of RAS, and chlorthalidone comprise a common what?. ### Response: 3-drug regimen.


Instruction: What provides substantial BP reduction when compared with placebo?

Output: spironolac-tone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides substantial BP reduction when compared with placebo?. ### Response: spironolac-tone.


Instruction: What is the name of the RCT that demonstrated the superiority of spironolactone over alpha and beta blockers?

Output: PATHWAY-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the RCT that demonstrated the superiority of spironolactone over alpha and beta blockers?. ### Response: PATHWAY-2.


Instruction: What is effective in achieving BP control?

Output: hydralazine or minoxidil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective in achieving BP control?. ### Response: hydralazine or minoxidil.


Instruction: What is effective in achieving BP control in patients resistant to usual combination therapy?

Output: hydralazine or minoxidil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective in achieving BP control in patients resistant to usual combination therapy?. ### Response: hydralazine or minoxidil.


Instruction: What may be best optimized by hypertension specialists?

Output: The dosing of multidrug regimens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be best optimized by hypertension specialists?. ### Response: The dosing of multidrug regimens.


Instruction: Several studies have investigated devices that interrupt what activity?

Output: sympathetic nerve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Several studies have investigated devices that interrupt what activity?. ### Response: sympathetic nerve.


Instruction: What are two examples of nerve activity?

Output: carotid baroreceptor pacing and catheter ablation of renal sympathetic nerves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two examples of nerve activity?. ### Response: carotid baroreceptor pacing and catheter ablation of renal sympathetic nerves.


Instruction: When will the ahajournals.org be available?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the ahajournals.org be available?. ### Response: May 3, 2023.


Instruction: What is Kidney International Supplements 2013 3?

Output: 271–279

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Kidney International Supplements 2013 3?. ### Response: 271–279.


Instruction: What is chapter 2 of the journal?

Output: Kidney International Supplements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is chapter 2 of the journal?. ### Response: Kidney International Supplements.


Instruction: What is ful electrical cardioversion in patients with hyperthyroidism-induced persistent atrial fibrillation?

Output: ver-sus non-hyperthyroidism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ful electrical cardioversion in patients with hyperthyroidism-induced persistent atrial fibrillation?. ### Response: ver-sus non-hyperthyroidism.


Instruction: What is the name of the study that compares the efficacy and safety of new oral medications?

Output: a meta-analysis of randomised trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares the efficacy and safety of new oral medications?. ### Response: a meta-analysis of randomised trials.


Instruction: What is the name of the meta-analysis of randomised trials of oral anticoagulants and war-farin in patients with atrial fibrillation?

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of randomised trials of oral anticoagulants and war-farin in patients with atrial fibrillation?. ### Response: Lancet.


Instruction: What was the title of the study that compared the efficacy and safety of anticoagulant with warfarin?

Output: a meta-analysis of randomised trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the study that compared the efficacy and safety of anticoagulant with warfarin?. ### Response: a meta-analysis of randomised trials.


Instruction: Who was the author of this study?

Output: Jaillard A, Cornu C, Durieux A, Moulin T, Boutitie F, Lees KR, Hommel M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of this study?. ### Response: Jaillard A, Cornu C, Durieux A, Moulin T, Boutitie F, Lees KR, Hommel M.


Instruction: What is the risk of atrial fibrillation after atrial flutter ablation?

Output: impact of AF history, gender, and antiarrhyth-mic drug medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of atrial fibrillation after atrial flutter ablation?. ### Response: impact of AF history, gender, and antiarrhyth-mic drug medication.


Instruction: What are the effects of AF history, gender, and antiarrhyth-mic drug medication?

Output: Risk of atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects of AF history, gender, and antiarrhyth-mic drug medication?. ### Response: Risk of atrial fibrillation.


Instruction: What is the name of the randomised controlled trial?

Output: ACTIVE W

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial?. ### Response: ACTIVE W.


Instruction: What is ACTIVE W?

Output: a randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACTIVE W?. ### Response: a randomised controlled trial.


Instruction: When was the MAST-E study conducted?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the MAST-E study conducted?. ### Response: 1999.


Instruction: How many strokes were there in 1999?

Output: 30:1326–1332

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 1999?. ### Response: 30:1326–1332.


Instruction: What is the name of the 2018 guideline for the early management of patients with acute ischemic stroke?

Output: a guideline for healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2018 guideline for the early management of patients with acute ischemic stroke?. ### Response: a guideline for healthcare professionals.


Instruction: When was the journal 30:1326-1332 published?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the journal 30:1326-1332 published?. ### Response: 1999.


Instruction: What is a guideline for healthcare professionals from the American Heart Association/American Stroke Association?

Output: Guidelines for the early management of patients with acute ischemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a guideline for healthcare professionals from the American Heart Association/American Stroke Association?. ### Response: Guidelines for the early management of patients with acute ischemic stroke.


Instruction: How many patients with acute ischemic stroke are covered by this guideline?

Output: 450

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with acute ischemic stroke are covered by this guideline?. ### Response: 450.


Instruction: What is the 2018 European Heart Rhythm Association practical guide on the use of non-vitamin K antagonist oral an-ticoagulants in patients with atrial fibrillation?

Output: executive summary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 European Heart Rhythm Association practical guide on the use of non-vitamin K antagonist oral an-ticoagulants in patients with atrial fibrillation?. ### Response: executive summary.


Instruction: What is the name of the executive summary of fibrillation?

Output: The 2018 European Heart Rhythm Association practical guide on the use of non-vitamin K antagonist oral an-ticoagulants in patients with atrial fibrillation: executive summary. Europace

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the executive summary of fibrillation?. ### Response: The 2018 European Heart Rhythm Association practical guide on the use of non-vitamin K antagonist oral an-ticoagulants in patients with atrial fibrillation: executive summary. Europace.


Instruction: What are the names of the members of the Europace team?

Output: Muscari A, Faccioli L, Lega MV, Lorusso A, Masetti M, Pastore Trossello M, Puddu GM, Spinardi L, Zoli M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the members of the Europace team?. ### Response: Muscari A, Faccioli L, Lega MV, Lorusso A, Masetti M, Pastore Trossello M, Puddu GM, Spinardi L, Zoli M.


Instruction: How is hemorrhagic transformation predicted in nonlacunar strokes?

Output: maximum cerebral lesion diameter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is hemorrhagic transformation predicted in nonlacunar strokes?. ### Response: maximum cerebral lesion diameter.


Instruction: What is the name of the disease that causes ischemic strokes?

Output: hemorrhagic transformation and its timing from maximum cerebral lesion diameter in nonlacunar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes ischemic strokes?. ### Response: hemorrhagic transformation and its timing from maximum cerebral lesion diameter in nonlacunar.


Instruction: What does Brain Behav 2020 do?

Output: Predicting hemorrhagic transformation and its timing from maximum cerebral lesion diameter in nonlacunar ischemic strokes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Brain Behav 2020 do?. ### Response: Predicting hemorrhagic transformation and its timing from maximum cerebral lesion diameter in nonlacunar ischemic strokes.