Instruction: What was the larger cohort of patients in the CONFIRM-HF trial?

Output: n=304

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the larger cohort of patients in the CONFIRM-HF trial?. ### Response: n=304.


Instruction: How many patients were included in the failure trial174?

Output: 304

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were included in the failure trial174?. ### Response: 304.


Instruction: How many prospective controlled studies evaluated the effect of intravenous iron on deaths, hospitalizations, and other events in patients with HF and iron deficiency?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prospective controlled studies evaluated the effect of intravenous iron on deaths, hospitalizations, and other events in patients with HF and iron deficiency?. ### Response: 5.


Instruction: What does HF and iron deficiency have in common?

Output: intravenous iron in HF associated with iron deficiency. Therefore, a strong recommendation for intravenous iron repletion must await the results of an appropriately powered trial on morbidity and mortality. There is an uncertain evidence base for oral iron repletion in the setting of anemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HF and iron deficiency have in common?. ### Response: intravenous iron in HF associated with iron deficiency. Therefore, a strong recommendation for intravenous iron repletion must await the results of an appropriately powered trial on morbidity and mortality. There is an uncertain evidence base for oral iron repletion in the setting of anemia.


Instruction: What did patients receiving intravenous iron experience?

Output: limited but statistically significant improvements in functional capacity and LVEF but no reduction in mortality rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients receiving intravenous iron experience?. ### Response: limited but statistically significant improvements in functional capacity and LVEF but no reduction in mortality rate.


Instruction: The FAIR-HF 2 trial is underway to further address the potential benefit of what?

Output: intravenous iron

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The FAIR-HF 2 trial is underway to further address the potential benefit of what?. ### Response: intravenous iron.


Instruction: What is associated with HF associated with iron deficiency?

Output: intravenous iron

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with HF associated with iron deficiency?. ### Response: intravenous iron.


Instruction: A strong recommendation for intravenous iron repletion must await the results of an appropriately powered trial on what?

Output: morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A strong recommendation for intravenous iron repletion must await the results of an appropriately powered trial on what?. ### Response: morbidity and mortality.


Instruction: There is an uncertain evidence base for what in the setting of anemia?

Output: oral iron repletion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is an uncertain evidence base for what in the setting of anemia?. ### Response: oral iron repletion.


Instruction: What type of anemia is associated with HF?

Output: Stage C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of anemia is associated with HF?. ### Response: Stage C.


Instruction: What are the recommendations for Stage C HFpEF?

Output: COR LOE Recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for Stage C HFpEF?. ### Response: COR LOE Recommendations.


Instruction: When will the recommendations be available for download?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the recommendations be available for download?. ### Response: May 3, 2023.


Instruction: What has been used to reduce recurrent arrhythmias in long QT syndrome type 3?

Output: ranolazine, mexiletine, and flecainide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been used to reduce recurrent arrhythmias in long QT syndrome type 3?. ### Response: ranolazine, mexiletine, and flecainide.


Instruction: What is the name of the 2017 VA/SCD Guideline?

Output: Al-Khatib et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2017 VA/SCD Guideline?. ### Response: Al-Khatib et al.


Instruction: What is the yield of genetic testing in long QT syndrome phenotype-positive patients?

Output: 50% to 86%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the yield of genetic testing in long QT syndrome phenotype-positive patients?. ### Response: 50% to 86%,.


Instruction: What is important diagnostic, prognostic, and therapeutic information?

Output: Genetic testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important diagnostic, prognostic, and therapeutic information?. ### Response: Genetic testing.


Instruction: What percentage of syndrome phenotype-positive patients is 50% to 86%?

Output: The yield of genetic testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of syndrome phenotype-positive patients is 50% to 86%?. ### Response: The yield of genetic testing.


Instruction: What is the higher range present in patients with marked QT prolongation or positive family history of SCD?

Output: S7.9.1.1-17,S7.9.1.1-21,S7.9.1.1-53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the higher range present in patients with marked QT prolongation or positive family history of SCD?. ### Response: S7.9.1.1-17,S7.9.1.1-21,S7.9.1.1-53.


Instruction: A negative genetic test does not exclude what?

Output: the diagnosis of long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A negative genetic test does not exclude what?. ### Response: the diagnosis of long QT syndrome.


Instruction: What may genetic testing help in asymptomatic patients with oth-erwise unexplained prolonged QTc 480 ms on serial ECGs?

Output: con-firm the diagnosis and supplement prognostic information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may genetic testing help in asymptomatic patients with oth-erwise unexplained prolonged QTc 480 ms on serial ECGs?. ### Response: con-firm the diagnosis and supplement prognostic information.


Instruction: What may help con-firm the diagnosis and supplement prognostic information in addition to clinical symptoms?

Output: genetic testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may help con-firm the diagnosis and supplement prognostic information in addition to clinical symptoms?. ### Response: genetic testing.


Instruction: What type of testing did patients with suspected long QT syndrome undergo?

Output: exercise treadmill testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of testing did patients with suspected long QT syndrome undergo?. ### Response: exercise treadmill testing.


Instruction: Patients with a history of syncope or cardiac arrest and an affected first-degree relative underwent exercise treadmill testing and what else?

Output: bicycle exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with a history of syncope or cardiac arrest and an affected first-degree relative underwent exercise treadmill testing and what else?. ### Response: bicycle exercise.


Instruction: What was confirmed by genetic testing in all affected individuals?

Output: long QT syn-drome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was confirmed by genetic testing in all affected individuals?. ### Response: long QT syn-drome.


Instruction: What did prolongation of the 4-minute recovery QTc have high sensitivity for correctly identifying patients with long QT syndrome?

Output: line-to-normal resting QTc intervals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did prolongation of the 4-minute recovery QTc have high sensitivity for correctly identifying patients with long QT syndrome?. ### Response: line-to-normal resting QTc intervals.


Instruction: What is high sensitivity for correctly identifying patients with long QT syndrome?

Output: line-to-normal resting QTc intervals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is high sensitivity for correctly identifying patients with long QT syndrome?. ### Response: line-to-normal resting QTc intervals.


Instruction: A study in younger patients demonstrated QTc prolongation >460 ms at 7 minutes of recovery.

Output: S7.9.1.1-27 A study in younger patients demonstrated QTc prolongation >460 ms at 7 minutes of recovery predicted long QT syndrome type 1 or long QT syndrome type 2 patients versus controls

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A study in younger patients demonstrated QTc prolongation >460 ms at 7 minutes of recovery.. ### Response: S7.9.1.1-27 A study in younger patients demonstrated QTc prolongation >460 ms at 7 minutes of recovery predicted long QT syndrome type 1 or long QT syndrome type 2 patients versus controls.


Instruction: What did a study using burst bicycle exercise predict?

Output: long QT syndrome type 1 or long QT syndrome type 2 patients versus controls

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a study using burst bicycle exercise predict?. ### Response: long QT syndrome type 1 or long QT syndrome type 2 patients versus controls.


Instruction: What did a study using burst bicycle exercise show?

Output: patients with latent long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a study using burst bicycle exercise show?. ### Response: patients with latent long QT syndrome.


Instruction: What did patients with latent long QT syndrome have a significantly greater increase in with exercise than controls or those with QTc prolongation at baseline?

Output: QTc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients with latent long QT syndrome have a significantly greater increase in with exercise than controls or those with QTc prolongation at baseline?. ### Response: QTc.


Instruction: What can be beneficial in school-aged patients?

Output: Monitoring ade-quacy of beta-blocker therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial in school-aged patients?. ### Response: Monitoring ade-quacy of beta-blocker therapy.


Instruction: What may be associated with a decrease in supine and peak exercise QTc?

Output: Beta-blocker ther -apy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with a decrease in supine and peak exercise QTc?. ### Response: Beta-blocker ther -apy.


Instruction: Beta-blocker ther -apy is associated with what?

Output: a decrease in supine and peak exercise QTc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beta-blocker ther -apy is associated with what?. ### Response: a decrease in supine and peak exercise QTc.


Instruction: What percentage of patients with long QT syndrome have QTc intervals 440 ms?

Output: 10% to 36%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with long QT syndrome have QTc intervals 440 ms?. ### Response: 10% to 36%.


Instruction: What type of syndrome type 1 patients have C-loop mutations.

Output: long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of syndrome type 1 patients have C-loop mutations.. ### Response: long QT syndrome.


Instruction: What is HBPM used for in ACC/AHA Stage 1?

Output: Management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HBPM used for in ACC/AHA Stage 1?. ### Response: Management.


Instruction: What is the percentage of patients 18-85?

Output: All patients 18–85 y of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of patients 18-85?. ### Response: All patients 18–85 y of age.


Instruction: What percentage of patients have a diagnosis of ACC/AHA stage 1 HBP for whom HBPM is recommended and data are documented in the patient recordNumerator Documentation of home BP readings in the medical record?

Output: 18–85 y of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have a diagnosis of ACC/AHA stage 1 HBP for whom HBPM is recommended and data are documented in the patient recordNumerator Documentation of home BP readings in the medical record?. ### Response: 18–85 y of age.


Instruction: What is the name of all patients with HBP who had at least 1 outpatient encounter with a diagnosis of HBP during the first 6 mo of the measurement year or any time before the measurement period?

Output: 18–85 y of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of all patients with HBP who had at least 1 outpatient encounter with a diagnosis of HBP during the first 6 mo of the measurement year or any time before the measurement period?. ### Response: 18–85 y of age.


Instruction: End-stage renal disease, kidney transplantation, etc. are excluded from the definition of what?

Output: Denominator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: End-stage renal disease, kidney transplantation, etc. are excluded from the definition of what?. ### Response: Denominator.


Instruction: Before the measurement period what is excluded?

Output: End-stage renal disease, kidney transplantation, pregnancy, BP readings taken during an inpatient stay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Before the measurement period what is excluded?. ### Response: End-stage renal disease, kidney transplantation, pregnancy, BP readings taken during an inpatient stay.


Instruction: What is excluded during an inpatient stay?

Output: End-stage renal disease, kidney transplantation, pregnancy, BP readings taken

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is excluded during an inpatient stay?. ### Response: End-stage renal disease, kidney transplantation, pregnancy, BP readings taken.


Instruction: How many mo/measurement year is the measurement period?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mo/measurement year is the measurement period?. ### Response: 12.


Instruction: What does HBPM stand for?

Output: self-monitoring of BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HBPM stand for?. ### Response: self-monitoring of BP.


Instruction: What is the term for self-monitoring of BP?

Output: HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for self-monitoring of BP?. ### Response: HBPM.


Instruction: What does BP refer to?

Output: auscultatory devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does BP refer to?. ### Response: auscultatory devices.


Instruction: What has been found to be a better predictor of cardiovascular risk than clinic-based measurement?

Output: Home-based measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been found to be a better predictor of cardiovascular risk than clinic-based measurement?. ### Response: Home-based measurement.


Instruction: Evidence suggests that home-based BP measurement in combination with what?

Output: telemedicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence suggests that home-based BP measurement in combination with what?. ### Response: telemedicine.


Instruction: Home-based BP measurement in combination with telemedicine with nurse- or pharmacist-led care may be effective for what?

Output: improving hypertension management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Home-based BP measurement in combination with telemedicine with nurse- or pharmacist-led care may be effective for what?. ### Response: improving hypertension management.


Instruction: What should occur under medical supervision?

Output: Patient training

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should occur under medical supervision?. ### Response: Patient training.


Instruction: What type of devices are not generally useful for hypertension?

Output: auscultatory devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of devices are not generally useful for hypertension?. ### Response: auscultatory devices.


Instruction: What is the name of a device that can be used to check blood pressure?

Output: auscultatory devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a device that can be used to check blood pressure?. ### Response: auscultatory devices.


Instruction: What is not generally useful for HBPM because patients rarely master the technique required for measuring BP with auscultatory devices?

Output: Use of auscultatory devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not generally useful for HBPM because patients rarely master the technique required for measuring BP with auscultatory devices?. ### Response: Use of auscultatory devices.


Instruction: What are monitors with provision for storage of readings in memory preferred?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are monitors with provision for storage of readings in memory preferred?. ### Response: •.


Instruction: What should a patient do if there are significant differences in BPs?

Output: measure BPs in the arm with higher readings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient do if there are significant differences in BPs?. ### Response: measure BPs in the arm with higher readings.


Instruction: What should the patient do when there are differences?

Output: measure BPs in the arm with higher readings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the patient do when there are differences?. ### Response: measure BPs in the arm with higher readings.


Instruction: How long before BP measurements should you avoid smoking, caffeinated beverages, or exercise?

Output: 30 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before BP measurements should you avoid smoking, caffeinated beverages, or exercise?. ### Response: 30 min.


Instruction: What is surprising about environmental tobacco smoke?

Output: lack of a dose-response relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is surprising about environmental tobacco smoke?. ### Response: lack of a dose-response relationship.


Instruction: What may explain the lack of a dose-response relationship?

Output: physiological studies suggesting a tobacco smoke exposure threshold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may explain the lack of a dose-response relationship?. ### Response: physiological studies suggesting a tobacco smoke exposure threshold.


Instruction: Recent studies of the effects of smok-ing bans in communities have shown that bans are what?

Output: reduction in the risk of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent studies of the effects of smok-ing bans in communities have shown that bans are what?. ### Response: reduction in the risk of stroke.


Instruction: What has been shown to reduce the risk of stroke?

Output: smok-ing bans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to reduce the risk of stroke?. ### Response: smok-ing bans.


Instruction: When did Arizona enact a statewide ban on smoking in most indoor public places?

Output: After

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Arizona enact a statewide ban on smoking in most indoor public places?. ### Response: After.


Instruction: What was the reduction in strokes in counties that had not banned smoking?

Output: 14%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in strokes in counties that had not banned smoking?. ### Response: 14%.


Instruction: What was the reduction in strokes in counties that had not previously had a ban in place?

Output: 14%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in strokes in counties that had not previously had a ban in place?. ### Response: 14%.


Instruction: What did a study of New York State not find a reduction in when it enacted a comprehensive smoking ban?

Output: strokes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a study of New York State not find a reduction in when it enacted a comprehensive smoking ban?. ### Response: strokes.


Instruction: What does smoking likely contribute to?

Output: increased stroke risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does smoking likely contribute to?. ### Response: increased stroke risk.


Instruction: How much does smoking increase heart rate, mean BP, and cardiac risk?

Output: as little as a single cigarette

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does smoking increase heart rate, mean BP, and cardiac risk?. ### Response: as little as a single cigarette.


Instruction: What is smoking as little as a single cigarette known to do?

Output: increases heart rate, mean BP, and cardiac index and decreases arterial dis-tensibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is smoking as little as a single cigarette known to do?. ### Response: increases heart rate, mean BP, and cardiac index and decreases arterial dis-tensibility.


Instruction: What increases heart rate, mean BP, and cardiac index?

Output: Smoking as little as a single cigarette

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases heart rate, mean BP, and cardiac index?. ### Response: Smoking as little as a single cigarette.


Instruction: What decreases arterial dis-tensibility?

Output: Smoking as little as a single cigarette

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What decreases arterial dis-tensibility?. ### Response: Smoking as little as a single cigarette.


Instruction: Active and passive exposure to cigarette smoke is associated with what?

Output: the development of atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Active and passive exposure to cigarette smoke is associated with what?. ### Response: the development of atherosclerosis.


Instruction: cigarette smoking triples the risk of cryptogenic stroke among individuals with a low atherosclerotic burden and no evidence of a cardiac source of emboli?

Output: 357

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: cigarette smoking triples the risk of cryptogenic stroke among individuals with a low atherosclerotic burden and no evidence of a cardiac source of emboli?. ### Response: 357.


Instruction: What does smoking cessation reduce the risk of?

Output: stroke and other cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does smoking cessation reduce the risk of?. ### Response: stroke and other cardiovascular events.


Instruction: What is a rapid reduction in risk of stroke and other cardiovascular events?

Output: Smoking cessa-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a rapid reduction in risk of stroke and other cardiovascular events?. ### Response: Smoking cessa-tion.


Instruction: What is difficult to achieve?

Output: sustained smoking cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is difficult to achieve?. ### Response: sustained smoking cessation.


Instruction: What are effective behavioral and pharmacological treatments for?

Output: nicotine dependence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are effective behavioral and pharmacological treatments for?. ### Response: nicotine dependence.


Instruction: In what year were comprehensive reviews and recommendations for smoking cessation provided?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year were comprehensive reviews and recommendations for smoking cessation provided?. ### Response: 2008.


Instruction: What is more effective than either therapy alone?

Output: The combination of counseling and medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more effective than either therapy alone?. ### Response: The combination of counseling and medications.


Instruction: What is the current date of nicotine replacement?

Output: January 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current date of nicotine replacement?. ### Response: January 2012.


Instruction: What did pharmacotherapy, bupropion, and varenicline compare to in a meta-anal-ysis current to January 2012?

Output: superior to inert control medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did pharmacotherapy, bupropion, and varenicline compare to in a meta-anal-ysis current to January 2012?. ### Response: superior to inert control medications.


Instruction: What did emerging evi-dence suggest?

Output: varenicline may be more cost-effective than nicotine replacement therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did emerging evi-dence suggest?. ### Response: varenicline may be more cost-effective than nicotine replacement therapy.


Instruction: Which is more cost-effective than nicotine replacement therapy?

Output: varenicline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which is more cost-effective than nicotine replacement therapy?. ### Response: varenicline.


Instruction: What may be more cost-effective than nicotine replacement therapy?

Output: varenicline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be more cost-effective than nicotine replacement therapy?. ### Response: varenicline.


Instruction: What year did Al-Khatib and colleagues publish their 2017 VA/SCD GuidelineCirculation. 2018;138:e272–e391?

Output: 2018;138:e272–e391. DOI: 10.1161/CIR.0000000000000549 September 25, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Al-Khatib and colleagues publish their 2017 VA/SCD GuidelineCirculation. 2018;138:e272–e391?. ### Response: 2018;138:e272–e391. DOI: 10.1161/CIR.0000000000000549 September 25, 2018.


Instruction: What is the DOI of the 2017 VA and SCD guideline?

Output: 10.1161/CIR.0000000000000549

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI of the 2017 VA and SCD guideline?. ### Response: 10.1161/CIR.0000000000000549.


Instruction: Which study did Connolly, Hallstrom, and Cappato conduct?

Output: Meta-analysis of the implantable cardioverter defibrillator secondary preven-tion trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which study did Connolly, Hallstrom, and Cappato conduct?. ### Response: Meta-analysis of the implantable cardioverter defibrillator secondary preven-tion trials.


Instruction: What is the difference between antiarrhythmics and implant-able defibrillators?

Output: near-fatal ventricular arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between antiarrhythmics and implant-able defibrillators?. ### Response: near-fatal ventricular arrhythmias.


Instruction: What was the name of the study in Hamburg?

Output: Canadian Implantable Defibrillator Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study in Hamburg?. ### Response: Canadian Implantable Defibrillator Study.


Instruction: When did the Eur Heart J issue 21:2071-8?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Eur Heart J issue 21:2071-8?. ### Response: 2000.


Instruction: What does the Utstein Resuscitation Registry Templates for out-of-hospital cardiac arrest do?

Output: update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Utstein Resuscitation Registry Templates for out-of-hospital cardiac arrest do?. ### Response: update.


Instruction: What is the name of the task force that was created by the International Liaison Committee?

Output: Task Force 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the task force that was created by the International Liaison Committee?. ### Response: Task Force 12.


Instruction: What is the acronym for the Heart and Stroke Foundation of Canada?

Output: International Liaison Committee on Resuscitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Heart and Stroke Foundation of Canada?. ### Response: International Liaison Committee on Resuscitation.


Instruction: What are the acronyms for the InterAmerican Heart Foundation and the Resuscitation Council of Southern Africa?

Output: International Liaison Committee on Resuscitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the acronyms for the InterAmerican Heart Foundation and the Resuscitation Council of Southern Africa?. ### Response: International Liaison Committee on Resuscitation.


Instruction: Who is a member of the American Heart Association Emergency Cardiovascular Care Committee?

Output: Link MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the American Heart Association Emergency Cardiovascular Care Committee?. ### Response: Link MS.


Instruction: What is the focus of the Task Force 12?

Output: emergency action plans, resuscitation, cardiopulmonary resuscitation, and automated external defibrilla-tors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the Task Force 12?. ### Response: emergency action plans, resuscitation, cardiopulmonary resuscitation, and automated external defibrilla-tors.


Instruction: What are some of the recommendations for competitive athletes with cardiovascular abnormalities?

Output: Eligibility and disqualifica-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the recommendations for competitive athletes with cardiovascular abnormalities?. ### Response: Eligibility and disqualifica-tion.


Instruction: What is a scientific statement from the American Heart Association and American College of Cardiology?

Output: Task Force 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scientific statement from the American Heart Association and American College of Cardiology?. ### Response: Task Force 12.


Instruction: Circulation 2015;132:e334–8. S6-42. What is the answer to out-of-hospital cardiac arrest?

Output: drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation 2015;132:e334–8. S6-42. What is the answer to out-of-hospital cardiac arrest?. ### Response: drugs.


Instruction: What is the primary prevention of SCD in patients with isschemic heart disease?

Output: implantable cardioverter defibrillator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention of SCD in patients with isschemic heart disease?. ### Response: implantable cardioverter defibrillator.


Instruction: What is a comparison of antiarrhythmic-drug ther -apy with implantable defibrillators in patients resuscitated from nearfatal ventricular arrhythmias?

Output: The AVID Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison of antiarrhythmic-drug ther -apy with implantable defibrillators in patients resuscitated from nearfatal ventricular arrhythmias?. ### Response: The AVID Investigators.


Instruction: What is CIDS?

Output: Canadian implantable defibrillator study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CIDS?. ### Response: Canadian implantable defibrillator study.


Instruction: What is the name of the randomized trial of the implantable cardioverter defibrillator against amiodarone?

Output: IDS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of the implantable cardioverter defibrillator against amiodarone?. ### Response: IDS.


Instruction: What are the names of the studies of implantable cardioverter defibrillator secondary preven-tion trials?

Output: AVID, CASH and CIDS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the studies of implantable cardioverter defibrillator secondary preven-tion trials?. ### Response: AVID, CASH and CIDS.


Instruction: What is the name of the study that compares antiarrhythmics vs implantable Defibrilator?

Output: Cardiac Arrest Study Hamburg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares antiarrhythmics vs implantable Defibrilator?. ### Response: Cardiac Arrest Study Hamburg.


Instruction: Where is the Cardiac Arrest Study?

Output: Hamburg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Cardiac Arrest Study?. ### Response: Hamburg.


Instruction: What may be useful for government agencies and third-party payers to develop and implement reimbursement schedules for patients with acute stroke?

Output: Addressing economic barriers to treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be useful for government agencies and third-party payers to develop and implement reimbursement schedules for patients with acute stroke?. ### Response: Addressing economic barriers to treatment.


Instruction: What has been revised from 2013 Stroke Systems of Care?

Output: IIb C-EORecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been revised from 2013 Stroke Systems of Care?. ### Response: IIb C-EORecommendation.


Instruction: How many studies have demonstrated substantial societal economic value for acute stroke treatment across multiple countries?

Output: Multiple studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have demonstrated substantial societal economic value for acute stroke treatment across multiple countries?. ### Response: Multiple studies.


Instruction: How much would be realized in the United States if the proportion of all ischemic stroke patients receiving IV alteplase was increased to 8%?

Output: $30 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much would be realized in the United States if the proportion of all ischemic stroke patients receiving IV alteplase was increased to 8%?. ### Response: $30 million.


Instruction: What is excluded from increased quality-adjusted life-years?

Output: any gain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is excluded from increased quality-adjusted life-years?. ### Response: any gain.


Instruction: What percentage excludes any gain from increased quality-adjusted life-years gained?

Output: 8%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage excludes any gain from increased quality-adjusted life-years gained?. ### Response: 8%..


Instruction: When was the Centers for Medicare & Medicaid Services Diagnosis-Related Group 559 payment implemented?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Centers for Medicare & Medicaid Services Diagnosis-Related Group 559 payment implemented?. ### Response: 2005.


Instruction: Why was treatment of acute stroke discouraged at a hospital level?

Output: high hospital cost-reimbursement ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was treatment of acute stroke discouraged at a hospital level?. ### Response: high hospital cost-reimbursement ratio.


Instruction: What is economically discouraged at a hospital level because of a high hospital cost-reimbursement ratio?

Output: treatment of acute stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is economically discouraged at a hospital level because of a high hospital cost-reimbursement ratio?. ### Response: treatment of acute stroke.


Instruction: Diagnosis-Related Group 559 favorably altered what for stroke care?

Output: cost-reimbursement ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diagnosis-Related Group 559 favorably altered what for stroke care?. ### Response: cost-reimbursement ratio.


Instruction: In a single-hospital study, this ratio decreased from 1.41 to what?

Output: 0.82

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a single-hospital study, this ratio decreased from 1.41 to what?. ### Response: 0.82.


Instruction: What percentage of the time was 0.82 after Diagnosis-Related Group 559?

Output: 0.66–0.97

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the time was 0.82 after Diagnosis-Related Group 559?. ### Response: 0.66–0.97.


Instruction: What was important to address as acute stroke care complexity evolves?

Output: economic barriers to treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was important to address as acute stroke care complexity evolves?. ### Response: economic barriers to treatment.


Instruction: Establishment of Data Repositories What is important?

Output: Addressing economic barriers to treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Establishment of Data Repositories What is important?. ### Response: Addressing economic barriers to treatment.


Instruction: How does acute stroke care complexity evolve?

Output: Addressing economic barriers to treatment is important

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does acute stroke care complexity evolve?. ### Response: Addressing economic barriers to treatment is important.


Instruction: What is the purpose of establishing a stroke data repository?

Output: to promote consistent adherence to current treatment guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of establishing a stroke data repository?. ### Response: to promote consistent adherence to current treatment guidelines.


Instruction: What is a part of a quality improvement process?

Output: stroke data repository

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a part of a quality improvement process?. ### Response: stroke data repository.


Instruction: What was reworded for clarity from 2013 AIS Guidelines?

Output: I B-NRRecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reworded for clarity from 2013 AIS Guidelines?. ### Response: I B-NRRecommendation.


Instruction: COR and LOE added to conform with what?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: COR and LOE added to conform with what?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: Data repository as a part of a quality improvement process was associated with improved IV alteplase administration after what?

Output: AIS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data repository as a part of a quality improvement process was associated with improved IV alteplase administration after what?. ### Response: AIS.


Instruction: Lower in-hospital mortality68b,68c and intracranial hemorrhage rates and an increase in the percentage of patients discharged home?

Output: Participation in a stroke data repository

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Lower in-hospital mortality68b,68c and intracranial hemorrhage rates and an increase in the percentage of patients discharged home?. ### Response: Participation in a stroke data repository.


Instruction: Data Supplement 1.1.9. Stroke System Care Quality Improvement Process What is COR LOE New, Revised, or Unchanged?

Output: Establishment of Data Repositories

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data Supplement 1.1.9. Stroke System Care Quality Improvement Process What is COR LOE New, Revised, or Unchanged?. ### Response: Establishment of Data Repositories.


Instruction: How many areas did the individual studies vary across?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many areas did the individual studies vary across?. ### Response: 3.


Instruction: How many increments were there if individual studies varied across 3 areas?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were there if individual studies varied across 3 areas?. ### Response: 2.


Instruction: What was the judgement of precision based on?

Output: visual inspection of t he confidence region

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the judgement of precision based on?. ### Response: visual inspection of t he confidence region.


Instruction: When was precision based on visual inspection of t he confidence region around the summary sensitivity and specificity point from the diagnostic meta -analysis?

Output: if a diagnostic meta -analysis was conducted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was precision based on visual inspection of t he confidence region around the summary sensitivity and specificity point from the diagnostic meta -analysis?. ### Response: if a diagnostic meta -analysis was conducted.


Instruction: When was imprecision assessed according to the range of what?

Output: point estimates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was imprecision assessed according to the range of what?. ### Response: point estimates.


Instruction: How was imprecision assessed?

Output: according to the range of  point estimates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was imprecision assessed?. ### Response: according to the range of  point estimates.


Instruction: What was assessed based on the range of point estimates?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was assessed based on the range of point estimates?. ### Response: imprecision.


Instruction: What is the name of the book published by the National Guideline Centre?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book published by the National Guideline Centre?. ### Response: Chronic Heart Failure.


Instruction: Who is the author of Chronic Heart Failure Methods?

Output: NICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Chronic Heart Failure Methods?. ### Response: NICE.


Instruction: What does the National Guideline Centre disclaim any responsibility for?

Output: damages arising out of the use or non -use of this guideline and the literature used in support of this guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the National Guideline Centre disclaim any responsibility for?. ### Response: damages arising out of the use or non -use of this guideline and the literature used in support of this guideline.


Instruction: What did the National Institute for Clinical Research commissioned?

Output: National Guideline Centre

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the National Institute for Clinical Research commissioned?. ### Response: National Guideline Centre.


Instruction: Who commissioned the National Guideline Centre to work on the guideline?

Output: National Institute for Health and Care Excellence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who commissioned the National Guideline Centre to work on the guideline?. ### Response: National Institute for Health and Care Excellence.


Instruction: What is the difference between cestac and enoxaparin in obese patients and patients with severe renal impairment?

Output: pharmacodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between cestac and enoxaparin in obese patients and patients with severe renal impairment?. ### Response: pharmacodynamics.


Instruction: What are the results of the ESSENCE and TIMI 11B studies?

Output: enoxaparin in patients who are obese and patients with severe renal impairment: analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the ESSENCE and TIMI 11B studies?. ### Response: enoxaparin in patients who are obese and patients with severe renal impairment: analysis.


Instruction: What did Cestac P, Bagheri H, Lapeyre-Mestre M, et al. find out about the use and safety of low molecular weight heparins in medical inpatients?

Output: Utilisation and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Cestac P, Bagheri H, Lapeyre-Mestre M, et al. find out about the use and safety of low molecular weight heparins in medical inpatients?. ### Response: Utilisation and safety.


Instruction: What is the name of the study conducted in medical inpatients?

Output: Drug Saf

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study conducted in medical inpatients?. ### Response: Drug Saf.


Instruction: How many patients were studied in 2003?

Output: 197 - 207

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were studied in 2003?. ### Response: 197 - 207.


Instruction: What is enoxaparin and bleeding complications?

Output: a review in patients with and without renal insufﬁ  ciency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin and bleeding complications?. ### Response: a review in patients with and without renal insufﬁ  ciency.


Instruction: What was a review in patients with and without renal insuffi ciency?

Output: Enoxaparin and bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a review in patients with and without renal insuffi ciency?. ### Response: Enoxaparin and bleeding complications.


Instruction: How many ( 7 ) were there in 2000?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 7 ) were there in 2000?. ### Response: 20.


Instruction: What is the pharmacokinetics of a drug?

Output: comparative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pharmacokinetics of a drug?. ### Response: comparative.


Instruction: What is Jariwala's name?

Output: N

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Jariwala's name?. ### Response: N.


Instruction: What is enoxaparin used for in obese volunteers?

Output: pharma-cokinetics and pharmacodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin used for in obese volunteers?. ### Response: pharma-cokinetics and pharmacodynamics.


Instruction: How many ( 3 ): 308-318 in 2002?

Output: 72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 3 ): 308-318 in 2002?. ### Response: 72.


Instruction: Rabbat CG, Cook CG, What is the name of the drug used in obese patients?

Output: enoxaparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Rabbat CG, Cook CG, What is the name of the drug used in obese patients?. ### Response: enoxaparin.


Instruction: What is Dalteparin thromboprophylaxis for critically ill medical-surgical patients with renal insufficiency?

Output: low-molecular-weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Dalteparin thromboprophylaxis for critically ill medical-surgical patients with renal insufficiency?. ### Response: low-molecular-weight heparin.


Instruction: What is the name of the group that studies critical care?

Output: Canadian Critical Care Trials Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies critical care?. ### Response: Canadian Critical Care Trials Group.


Instruction: How many cases were there in 2005?

Output: 357 - 363

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases were there in 2005?. ### Response: 357 - 363.


Instruction: What was the number of cases?

Output: 167

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the number of cases?. ### Response: 167.


Instruction: What is dalteparin used for in critically ill patients?

Output: Prophylaxis against deep vein thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is dalteparin used for in critically ill patients?. ### Response: Prophylaxis against deep vein thrombosis.


Instruction: What is the DIRECT study?

Output: Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufﬁ  ciency with the low-molecular-weight heparin dalteparin: an assessment of safety and pharmacodynamics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DIRECT study?. ### Response: Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufﬁ  ciency with the low-molecular-weight heparin dalteparin: an assessment of safety and pharmacodynamics.


Instruction: How many years was Tinzaparin used?

Output: eight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years was Tinzaparin used?. ### Response: eight.


Instruction: What year did Tinzaperin first appear in the literature?

Output: 1987

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Tinzaperin first appear in the literature?. ### Response: 1987.


Instruction: Tinzaparin and enox-aparin given at prophylactic dose for eight days in medical elderly patients with impaired renal function: a comparative pharmacokinetic study?

Output: M ,  Drouet   L ,  et al .

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tinzaparin and enox-aparin given at prophylactic dose for eight days in medical elderly patients with impaired renal function: a comparative pharmacokinetic study?. ### Response: M ,  Drouet   L ,  et al ..


Instruction: How many pages were there in the 97 ( 4 ): 581 - 586?

Output: 168

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages were there in the 97 ( 4 ): 581 - 586?. ### Response: 168.


Instruction: What is the molecular weight of heparin?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the molecular weight of heparin?. ### Response: low.


Instruction: What are the effects on eicosanoids, clotting and complement factors?

Output: Protamine reversal of anticoagulation achieved with a low molecular weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects on eicosanoids, clotting and complement factors?. ### Response: Protamine reversal of anticoagulation achieved with a low molecular weight heparin.


Instruction: What is PK 10169?

Output: Partial rever-sal of low molecular weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PK 10169?. ### Response: Partial rever-sal of low molecular weight heparin.


Instruction: What is the name of the drug that has a low molecular weight?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that has a low molecular weight?. ### Response: heparin.


Instruction: What is the effect of protamine sulfate on Xa activation?

Output: Partial rever-sal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of protamine sulfate on Xa activation?. ### Response: Partial rever-sal.


Instruction: How many. 170. Racanelli A, Fareed J, Walenga JM, Coyne E. Biochemical and pharmacologic studies on the protamine interactions. 2012 American College of Chest.

Output: 170

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many. 170. Racanelli A, Fareed J, Walenga JM, Coyne E. Biochemical and pharmacologic studies on the protamine interactions. 2012 American College of Chest.. ### Response: 170.


Instruction: What year was the American College of Chest Physicians founded?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the American College of Chest Physicians founded?. ### Response: 2012.


Instruction: Who wrote the book The Protamine Interactions?

Output: Kimberly Henricks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the book The Protamine Interactions?. ### Response: Kimberly Henricks.


Instruction: On what date was the book released?

Output: February 10, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was the book released?. ### Response: February 10, 2012.


Instruction: How does quality affect two- and three-dimensional echocardiographic determi-nation of left ventricular volumes?

Output: comparison with magnetic resonance imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does quality affect two- and three-dimensional echocardiographic determi-nation of left ventricular volumes?. ### Response: comparison with magnetic resonance imaging.


Instruction: What is a comparison with magnetic resonance imaging?

Output: quality influence two- and three-dimensional echocardiographic determi-nation of left ventricular volumes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison with magnetic resonance imaging?. ### Response: quality influence two- and three-dimensional echocardiographic determi-nation of left ventricular volumes.


Instruction: How does additive value of LV end-systolic measure?

Output: ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does additive value of LV end-systolic measure?. ### Response: ejection fraction.


Instruction: What causes leaflet prolapse?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes leaflet prolapse?. ### Response: Pulmonary hypertension.


Instruction: What is the additive value of left ventricular end-systolic dimension to ejection fraction?

Output: Predicting left ventricular dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the additive value of left ventricular end-systolic dimension to ejection fraction?. ### Response: Predicting left ventricular dysfunction.


Instruction: When did Eur J Echocardiogr. 2011 12:702-10?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Echocardiogr. 2011 12:702-10?. ### Response: 2011.


Instruction: How long did it take to analyze the effects of recurrent mitral regurgitation following mitral valve repair?

Output: long-term

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to analyze the effects of recurrent mitral regurgitation following mitral valve repair?. ### Response: long-term.


Instruction: What are competing outcomes?

Output: early surgery versus con-ventional treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are competing outcomes?. ### Response: early surgery versus con-ventional treatment.


Instruction: What is multimodality imaging for in mitral regurgitation?

Output: patient selection and pro-cedural guidance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is multimodality imaging for in mitral regurgitation?. ### Response: patient selection and pro-cedural guidance.


Instruction: Who developed the guidelines for the evaluation of val-vular regurgitation after percutaneous valve repair or replacement?

Output: American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed the guidelines for the evaluation of val-vular regurgitation after percutaneous valve repair or replacement?. ### Response: American Society of Echocardiography.


Instruction: What was developed in collaboration with the Society for Cardiovascular Aniography and Interventions?

Output: Guidelines for the evaluation of val-vular regurgitation after percutaneous valve repair or replacement: a report from the American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed in collaboration with the Society for Cardiovascular Aniography and Interventions?. ### Response: Guidelines for the evaluation of val-vular regurgitation after percutaneous valve repair or replacement: a report from the American Society of Echocardiography.


Instruction: What does Society for Cardiovascular Magnetic Resonance stand for?

Output: Society for Cardiovascular Angiography and Interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Society for Cardiovascular Magnetic Resonance stand for?. ### Response: Society for Cardiovascular Angiography and Interventions.


Instruction: What is the J Am Soc Echocardiogr. 2019;32:431–75.7.2.2.2?

Output: Diagnostic Testing: Changing Signs or Symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Soc Echocardiogr. 2019;32:431–75.7.2.2.2?. ### Response: Diagnostic Testing: Changing Signs or Symptoms.


Instruction: Who is Antoine C, Benfari G, Michelena HI?

Output: Antoine C, Benfari G, Michelena HI, et al. Clinical outcome of degenera-tive mitral regurgitation: critical importance of echocardiographic quanti-tative assessment in routine practice. Circulation. 2018;138:1317–26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Antoine C, Benfari G, Michelena HI?. ### Response: Antoine C, Benfari G, Michelena HI, et al. Clinical outcome of degenera-tive mitral regurgitation: critical importance of echocardiographic quanti-tative assessment in routine practice. Circulation. 2018;138:1317–26.


Instruction: What is the role of preop-erative symptoms on survival after surgical correction of organic mitral regurgitation?

Output: rationale for optimizing surgical indications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of preop-erative symptoms on survival after surgical correction of organic mitral regurgitation?. ### Response: rationale for optimizing surgical indications.


Instruction: What is Routine Follow-Up?

Output: Diagnostic Testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Routine Follow-Up?. ### Response: Diagnostic Testing.


Instruction: What affects short- and long-term survival after mitral valve operation for mitral regurgitation?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What affects short- and long-term survival after mitral valve operation for mitral regurgitation?. ### Response: Pulmonary hypertension.


Instruction: What does Pulmonary hypertension ad-verse affect?

Output: short- and long-term survival after mitral valve operation for mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Pulmonary hypertension ad-verse affect?. ### Response: short- and long-term survival after mitral valve operation for mitral regurgitation.


Instruction: What is the purpose of mitral valve operation for mitral regurgitation?

Output: timing of surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of mitral valve operation for mitral regurgitation?. ### Response: timing of surgery.


Instruction: What are implications for timing of surgery?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implications for timing of surgery?. ### Response: Pulmonary hypertension.


Instruction: When was J Thorac Car-diovasc Surg. 2011;142:1439–52?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was J Thorac Car-diovasc Surg. 2011;142:1439–52?. ### Response: 2011.


Instruction: What is the difference between early surgery and conventional treatment in asymptomatic severe mitral regurgitation?

Output: Comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between early surgery and conventional treatment in asymptomatic severe mitral regurgitation?. ### Response: Comparison.


Instruction: What is Bonow RO's specialty?

Output: Chronic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Bonow RO's specialty?. ### Response: Chronic.


Instruction: What was the name of the study?

Output: American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: American Society of Echocardiography.


Instruction: What did Avierinos J-F, Messika-Zeitoun D, and Enriquez-Sarano do?

Output: surgical correction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Avierinos J-F, Messika-Zeitoun D, and Enriquez-Sarano do?. ### Response: surgical correction.


Instruction: What is the focus of the 2015 ACC/AHA/SCAI Update?

Output: Primary PercutaneousCoronary Intervention for PatientsWith ST-Elevation Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the 2015 ACC/AHA/SCAI Update?. ### Response: Primary PercutaneousCoronary Intervention for PatientsWith ST-Elevation Myocardial Infarction.


Instruction: What was the 2013 guideline for the Management of ST-Elevation Myocardial Infarction?

Output: ACCF/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2013 guideline for the Management of ST-Elevation Myocardial Infarction?. ### Response: ACCF/AHA.


Instruction: Who is the Chair of the Latin American Society of Interventional Cardiology?

Output: Glenn N. Levine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of the Latin American Society of Interventional Cardiology?. ### Response: Glenn N. Levine.


Instruction: Who is the Vice Chair of the WritingCommittee?

Output: Deborah D. Ascheim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Chair of the WritingCommittee?. ### Response: Deborah D. Ascheim.


Instruction: What is the name of the MD, FACC, FAHA, FSCAI, Vice Chair?

Output: Frederick G. Kushner

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the MD, FACC, FAHA, FSCAI, Vice Chair?. ### Response: Frederick G. Kushner.


Instruction: Who is the MD, FACC, FSCAI?

Output: Jacqueline E. Tamis-Holland

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the MD, FACC, FSCAI?. ### Response: Jacqueline E. Tamis-Holland.


Instruction: What is the name of the MD who is the FAHA?

Output: Joseph Woo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the MD who is the FAHA?. ### Response: Joseph Woo.


Instruction: Who is required to recuse themselves from voting on sections to which their specific relationships with industry mayapply?

Output: Writing committee members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is required to recuse themselves from voting on sections to which their specific relationships with industry mayapply?. ### Response: Writing committee members.


Instruction: Who is a representative of the ACC/AHA Task Force on ClinicalPractice Guidelines Liaison?

Output: zSCAI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a representative of the ACC/AHA Task Force on ClinicalPractice Guidelines Liaison?. ### Response: zSCAI.


Instruction: Who is the Vice Chair of the Stemi WritingCommittee?

Output: Deborah D. Ascheim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Chair of the Stemi WritingCommittee?. ### Response: Deborah D. Ascheim.


Instruction: Who is the MD, MPH, MACC, FSCAI, FAHA?

Output: Ralph G. Brindis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the MD, MPH, MACC, FSCAI, FAHA?. ### Response: Ralph G. Brindis.


Instruction: What is the name of the doctor who is a doctor of medicine?

Output: Umesh N. Khot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the doctor who is a doctor of medicine?. ### Response: Umesh N. Khot.


Instruction: Who is a member of the FAHA?

Output: Joseph Woo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the FAHA?. ### Response: Joseph Woo.


Instruction: What is the name of the doctor?

Output: Umesh N. Khot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the doctor?. ### Response: Umesh N. Khot.


Instruction: Who is the MD?

Output: Umesh N. Khot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the MD?. ### Response: Umesh N. Khot.


Instruction: Where is Kristin Newby?

Output: MD, MHS, FACC, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Kristin Newby?. ### Response: MD, MHS, FACC, FAHA.


Instruction: What is the name of the doctor who accepted the award?

Output: Barry A. Franklin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the doctor who accepted the award?. ### Response: Barry A. Franklin.


Instruction: Who accepted the Award?

Output: Latin American Society of Interventional CardiologyPCI WritingCommittee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who accepted the Award?. ### Response: Latin American Society of Interventional CardiologyPCI WritingCommittee.


Instruction: What is one of the reasons why Deborah D. Ascheim accepted it?

Output: writing effort was completed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the reasons why Deborah D. Ascheim accepted it?. ### Response: writing effort was completed.


Instruction: Who accepted a position at Capricor Therapeutics in August 2015?

Output: Dr. Deborah D. Ascheim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who accepted a position at Capricor Therapeutics in August 2015?. ### Response: Dr. Deborah D. Ascheim.


Instruction: In accordance with ACC/AHA policy, who recused herself from the final voting process?

Output: Writing committee members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In accordance with ACC/AHA policy, who recused herself from the final voting process?. ### Response: Writing committee members.


Instruction: What year was the AMERICAN HEART ASSOCIATION, INC. founded?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the AMERICAN HEART ASSOCIATION, INC. founded?. ### Response: 2016.


Instruction: What is the ISBN number of the Society forCARDIOVASCULAR ANGIOGRAPHY AND INTERVENTIONS?

Output: 0735-1097

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ISBN number of the Society forCARDIOVASCULAR ANGIOGRAPHY AND INTERVENTIONS?. ### Response: 0735-1097.


Instruction: What is associated with lower risk of all-cause mortality in US adults?

Output: Higher diet quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with lower risk of all-cause mortality in US adults?. ### Response: Higher diet quality.


Instruction: What is higher diet quality asso-ciated with decreased risk of?

Output: all-cause cardiovascular disease and cancer mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is higher diet quality asso-ciated with decreased risk of?. ### Response: all-cause cardiovascular disease and cancer mortality.


Instruction: What is a link between RAAS activation and fibrinolysis?

Output: regeneration and vascular repair processes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a link between RAAS activation and fibrinolysis?. ### Response: regeneration and vascular repair processes.


Instruction: What induces the formation of plasminogen activator inhibitor-1 via an AT1 receptor-dependent effect on endothelial cells?

Output: Angiotensin II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What induces the formation of plasminogen activator inhibitor-1 via an AT1 receptor-dependent effect on endothelial cells?. ### Response: Angiotensin II.


Instruction: ACE downregulates what by degrading bradykinin?

Output: tissue plasminogen activator production

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ACE downregulates what by degrading bradykinin?. ### Response: tissue plasminogen activator production.


Instruction: What is a potent stimulator of endothelial tissue plasminogen activator expression?

Output: bradykinin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potent stimulator of endothelial tissue plasminogen activator expression?. ### Response: bradykinin.


Instruction: What do ACE inhibitors and ARBs limit in the vasculature?

Output: oxidative reactions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do ACE inhibitors and ARBs limit in the vasculature?. ### Response: oxidative reactions.


Instruction: Hypercholesterolemia upregulates what?

Output: the RAAS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypercholesterolemia upregulates what?. ### Response: the RAAS.


Instruction: The RAAS stimulates the accumulation of what in the arterial wall?

Output: low-density lipoprotein cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The RAAS stimulates the accumulation of what in the arterial wall?. ### Response: low-density lipoprotein cholesterol.


Instruction: What do these findings suggest may have clinically important vasoprotective effects beyond BP?

Output: antihypertensive drug classes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do these findings suggest may have clinically important vasoprotective effects beyond BP?. ### Response: antihypertensive drug classes.


Instruction: When will these findings be available?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will these findings be available?. ### Response: May 3, 2023.


Instruction: What is a marker of decongestion, dyspnea relief, and clinical outcomes among patients hospitalized with acute heart failure?

Output: C-reactive protein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a marker of decongestion, dyspnea relief, and clinical outcomes among patients hospitalized with acute heart failure?. ### Response: C-reactive protein.


Instruction: What does NT-ProBNP reduction predict during hospital stay?

Output: long-term mortality and readmission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NT-ProBNP reduction predict during hospital stay?. ### Response: long-term mortality and readmission.


Instruction: What predicts long-term mortality and readmission in heart failure patients?

Output: NT-ProBNP reduction percent-age during hospital stay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts long-term mortality and readmission in heart failure patients?. ### Response: NT-ProBNP reduction percent-age during hospital stay.


Instruction: What is NT-ProBNP reduction percentage during admission for acute decompensated heart failure?

Output: long-term cardiovascular mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NT-ProBNP reduction percentage during admission for acute decompensated heart failure?. ### Response: long-term cardiovascular mortality.


Instruction: What is a predictor of improvement and readmission in heart failure?

Output: C-reactive protein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of improvement and readmission in heart failure?. ### Response: C-reactive protein.


Instruction: What is the prognostic value of estab-lished and novel biomarkers in patients?

Output: galec-tin-3, a novel marker of fibrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic value of estab-lished and novel biomarkers in patients?. ### Response: galec-tin-3, a novel marker of fibrosis.


Instruction: What does PRIDE stand for?

Output: Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PRIDE stand for?. ### Response: Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department.


Instruction: What is the name of the program used to measure the inter -leukin family member ST2?

Output: International ST2 Consensus Panel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the program used to measure the inter -leukin family member ST2?. ### Response: International ST2 Consensus Panel.


Instruction: What is PRIDE?

Output: Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PRIDE?. ### Response: Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department.


Instruction: When was the PRIDE study conducted?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the PRIDE study conducted?. ### Response: 2007.


Instruction: What is ST2 a predictor of in patients with heart failure relative to?

Output: left ventricular ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ST2 a predictor of in patients with heart failure relative to?. ### Response: left ventricular ejection fraction.


Instruction: What was the 2011 Am J Cardiol. 107:259-67?

Output: Usefulness of soluble concentrations of interleukin family member ST2 as predictor of mortality in patients with acutely decompensated heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2011 Am J Cardiol. 107:259-67?. ### Response: Usefulness of soluble concentrations of interleukin family member ST2 as predictor of mortality in patients with acutely decompensated heart failure.


Instruction: What is Galectin-3 called in patients with heart failure?

Output: galec-tin-3, a novel marker of fibrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Galectin-3 called in patients with heart failure?. ### Response: galec-tin-3, a novel marker of fibrosis.


Instruction: What is the name of the drug that affects cardiac struc-ture and function?

Output: Galectin-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that affects cardiac struc-ture and function?. ### Response: Galectin-3.


Instruction: In what year did Eur J Heart Fail issue 12:826-832?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Eur J Heart Fail issue 12:826-832?. ### Response: 2010.


Instruction: What is a novel marker of fibrosis?

Output: galec-tin-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a novel marker of fibrosis?. ### Response: galec-tin-3.


Instruction: What is the predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction?

Output: renal insufficiency and survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction?. ### Response: renal insufficiency and survival.


Instruction: What is galec-tin-3?

Output: a novel marker of fibrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is galec-tin-3?. ### Response: a novel marker of fibrosis.


Instruction: When did the DEAL-HF study take place?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the DEAL-HF study take place?. ### Response: 2010.


Instruction: How does galectin-3 levels predict renal insufficiency and survival?

Output: Usefulness of plasma galectin-3 levels in systolic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does galectin-3 levels predict renal insufficiency and survival?. ### Response: Usefulness of plasma galectin-3 levels in systolic heart failure.


Instruction: What predicts renal insufficiency and survival?

Output: Usefulness of plasma galectin-3 levels in systolic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts renal insufficiency and survival?. ### Response: Usefulness of plasma galectin-3 levels in systolic heart failure.


Instruction: What is systolic heart failure used to predict?

Output: renal insufficiency and survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is systolic heart failure used to predict?. ### Response: renal insufficiency and survival.


Instruction: When did 108:385–90 appear in Am J Cardiol?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did 108:385–90 appear in Am J Cardiol?. ### Response: 2011.


Instruction: How did Tang WH, Wu Y, Grodin JL, et al. determine the prognostic value of Baseline and changes in Circulating Soluble ST2 levels?

Output: the International ST2 Consensus Panel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Tang WH, Wu Y, Grodin JL, et al. determine the prognostic value of Baseline and changes in Circulating Soluble ST2 levels?. ### Response: the International ST2 Consensus Panel.


Instruction: Decompensated heart failure. 2016;4:68–77.

Output: J Am Coll Cardiol HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Decompensated heart failure. 2016;4:68–77.. ### Response: J Am Coll Cardiol HF.


Instruction: The International ST2 Consensus Panel. 2015;115:26B–31B.

Output: Am J Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The International ST2 Consensus Panel. 2015;115:26B–31B.. ### Response: Am J Cardiol.


Instruction: What did spouses feel they would rather healthcare professionals make about deactivation so they didn't have to?

Output: decis ions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did spouses feel they would rather healthcare professionals make about deactivation so they didn't have to?. ### Response: decis ions.


Instruction: Why did healthcare professionals not have to make decisions about deactivation?

Output: staff or magnets were unavailable in community hospitals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did healthcare professionals not have to make decisions about deactivation?. ### Response: staff or magnets were unavailable in community hospitals.


Instruction: Why did professionals report reasons they were unable to deactivate ICDs?

Output: deactivation was often not possible out of h ours, when staff or magnets were unavailable in community hospitals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did professionals report reasons they were unable to deactivate ICDs?. ### Response: deactivation was often not possible out of h ours, when staff or magnets were unavailable in community hospitals.


Instruction: When were magnets or staff unavailable in community hospitals?

Output: unavailability of magnets or insufficient education on how to use magnets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were magnets or staff unavailable in community hospitals?. ### Response: unavailability of magnets or insufficient education on how to use magnets.


Instruction: What did some healthcare professionals find that consultants were unavailable to visit dying patients in the community to deactivate?

Output: ICDs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some healthcare professionals find that consultants were unavailable to visit dying patients in the community to deactivate?. ### Response: ICDs.


Instruction: What was the cause of excessive time delays?

Output: lack of defined process in  the community

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the cause of excessive time delays?. ### Response: lack of defined process in  the community.


Instruction: What did some people complain about?

Output: excessive time delays

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some people complain about?. ### Response: excessive time delays.


Instruction: How many phone calls did people have to make?

Output: lots

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many phone calls did people have to make?. ### Response: lots.


Instruction: How many phone calls did technicians have to make in order to access support for deactivation?

Output: lots

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many phone calls did technicians have to make in order to access support for deactivation?. ### Response: lots.


Instruction: What made the process of deactivating ICD long and difficult?

Output: there was no local or national policy or procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What made the process of deactivating ICD long and difficult?. ### Response: there was no local or national policy or procedures.


Instruction: What are some concerns about the coherence of the contributing studies with nothing to lower confidence?

Output: minor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some concerns about the coherence of the contributing studies with nothing to lower confidence?. ### Response: minor.


Instruction: What is a minor concern about the inadequacy of the evidence?

Output: the evidence provided reasonable depth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a minor concern about the inadequacy of the evidence?. ### Response: the evidence provided reasonable depth.


Instruction: What was the overall judgement of the sub-finding?

Output: moderate  confidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall judgement of the sub-finding?. ### Response: moderate  confidence.


Instruction: What concerns were there about the evidence?

Output: there was no local or national policy or procedures related to ICD deactivation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What concerns were there about the evidence?. ### Response: there was no local or national policy or procedures related to ICD deactivation.