Instruction: How many patients were included in the randomized controlled trial?

Output: 47

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were included in the randomized controlled trial?. ### Response: 47.


Instruction: What is chelation therapy used for?

Output: inter -mittent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is chelation therapy used for?. ### Response: inter -mittent.


Instruction: What is the name of the randomized trial of chellation therapy for isch-emic heart disease?

Output: TACT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of chellation therapy for isch-emic heart disease?. ### Response: TACT.


Instruction: What is the association of toenail cadmium levels with measures of sub-clinical atherosclerosis?

Output: the Coronary Artery Risk Development in Young Adults (CARDIA) Trace Element Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of toenail cadmium levels with measures of sub-clinical atherosclerosis?. ### Response: the Coronary Artery Risk Development in Young Adults (CARDIA) Trace Element Study.


Instruction: What is CARDIA?

Output: Coronary Artery Risk Development in Young Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CARDIA?. ### Response: Coronary Artery Risk Development in Young Adults.


Instruction: What is the name of the Trace Element Study?

Output: Coronary Artery Risk Development in Young Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Trace Element Study?. ### Response: Coronary Artery Risk Development in Young Adults.


Instruction: In what year was the Circulation 2012 published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Circulation 2012 published?. ### Response: 2012.


Instruction: How many deaths were associated with hypocalcemia from chelation therapy?

Output: 2003–2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths were associated with hypocalcemia from chelation therapy?. ### Response: 2003–2005.


Instruction: What is Edetate calcium disodium?

Output: CaNa2EDTA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Edetate calcium disodium?. ### Response: CaNa2EDTA.


Instruction: How many people died as a result of the CDC's study?

Output: 45

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people died as a result of the CDC's study?. ### Response: 45.


Instruction: When did CDC release their report?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did CDC release their report?. ### Response: 2012.


Instruction: Arora RR, Chou TM, Jain D, et al. What is the multicenter study of enhanced performance?

Output: 47

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arora RR, Chou TM, Jain D, et al. What is the multicenter study of enhanced performance?. ### Response: 47.


Instruction: What is NICE 2018?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: Chronic Heart Failure.


Instruction: What is the name of the study that compares telemonitoring to usual care?

Output: A single study (n=1437

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares telemonitoring to usual care?. ### Response: A single study (n=1437.


Instruction: How many studies were included for the outcome all -cause mortality?

Output: 9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included for the outcome all -cause mortality?. ### Response: 9.


Instruction: What was low quality and showed a clinically important reduction in deaths?

Output: all -cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was low quality and showed a clinically important reduction in deaths?. ### Response: all -cause mortality.


Instruction: How many studies did the outcome all -cause hospitalisation contain?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did the outcome all -cause hospitalisation contain?. ### Response: 6.


Instruction: What was a significant level of heterogeneity (I2=83%)?

Output: outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a significant level of heterogeneity (I2=83%)?. ### Response: outcome.


Instruction: What was I2=83%), unexplained by subgroup analysis for age, year of publication and intensity of intervention?

Output: heterogeneity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was I2=83%), unexplained by subgroup analysis for age, year of publication and intensity of intervention?. ### Response: heterogeneity.


Instruction: What was taken into consideration when judging the quality of the evidence?

Output: heterogeneity (I2=55%), unexplained by subgroup analysis for age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was taken into consideration when judging the quality of the evidence?. ### Response: heterogeneity (I2=55%), unexplained by subgroup analysis for age.


Instruction: For the outcome QoL the evidence ranged from high to what?

Output: very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For the outcome QoL the evidence ranged from high to what?. ### Response: very low quality.


Instruction: What scales showed no clinical effect?

Output: MLWHF t

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What scales showed no clinical effect?. ### Response: MLWHF t.


Instruction: What scale showed a clinically important improvement in QoL?

Output: SF -36

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What scale showed a clinically important improvement in QoL?. ### Response: SF -36.


Instruction: How did the mental component summary compare to the SF-36 scale?

Output: there was evidence of a clinically important reduction in QoL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the mental component summary compare to the SF-36 scale?. ### Response: there was evidence of a clinically important reduction in QoL.


Instruction: What component of QoL showed no clinical effect?

Output: physical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What component of QoL showed no clinical effect?. ### Response: physical.


Instruction: How many studies reported all -cause mortality alone?

Output: n=20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies reported all -cause mortality alone?. ### Response: n=20.


Instruction: What was the quality of the evidence?

Output: very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence?. ### Response: very low quality.


Instruction: What was low quality and did not demonstrate a clear effect with the confidence interval?

Output: The evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was low quality and did not demonstrate a clear effect with the confidence interval?. ### Response: The evidence.


Instruction: How many studies were included in the outcome all -cause hospitalisation?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included in the outcome all -cause hospitalisation?. ### Response: 6.


Instruction: What was the confidence interval ranging from a decrease and increase in all cause mortality?

Output: low quality and did not demonstrate a clear effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the confidence interval ranging from a decrease and increase in all cause mortality?. ### Response: low quality and did not demonstrate a clear effect.


Instruction: What was I2=55%)?

Output: heterogeneity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was I2=55%)?. ### Response: heterogeneity.


Instruction: For the outcome QoL the evidence ranged from low to what?

Output: very low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For the outcome QoL the evidence ranged from low to what?. ### Response: very low quality.


Instruction: What component of the SF -36 showed evidence of a clinically important improvement in QoL?

Output: physical functioning

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What component of the SF -36 showed evidence of a clinically important improvement in QoL?. ### Response: physical functioning.


Instruction: For the mental component summary, there was evidence of what?

Output: a clinically important reduction in QoL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For the mental component summary, there was evidence of what?. ### Response: a clinically important reduction in QoL.


Instruction: What is a clinically important reduction in QoL?

Output: mental component summary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a clinically important reduction in QoL?. ### Response: mental component summary.


Instruction: For the scale MLWHF t here was no evidence of a what?

Output: clinical effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For the scale MLWHF t here was no evidence of a what?. ### Response: clinical effect.


Instruction: Telemonitoring + structured telephone support Recent admission A single study looked at the effect of telemonitoring in addition to what other support?

Output: structured telephone support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Telemonitoring + structured telephone support Recent admission A single study looked at the effect of telemonitoring in addition to what other support?. ### Response: structured telephone support.


Instruction: What was the outcome all -cause mortality (low quality)?

Output: there was evidence of a clinically important reduction in deaths

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome all -cause mortality (low quality)?. ### Response: there was evidence of a clinically important reduction in deaths.


Instruction: What was evidence of a clinically important reduction in deaths?

Output: low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was evidence of a clinically important reduction in deaths?. ### Response: low quality.


Instruction: How long does it take to die from left-sided infective endocarditis?

Output: 6-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to die from left-sided infective endocarditis?. ### Response: 6-month.


Instruction: What is the name of the study that investigated the association between timing of valve surgery and 6-month mortal-ity?

Output: Heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the association between timing of valve surgery and 6-month mortal-ity?. ### Response: Heart.


Instruction: What is left-sided active infective endocarditis with or without involvement of the left heart?

Output: Left-Sided Intracardiac Solid Masses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is left-sided active infective endocarditis with or without involvement of the left heart?. ### Response: Left-Sided Intracardiac Solid Masses.


Instruction: How many years of single center experience?

Output: 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years of single center experience?. ### Response: 20.


Instruction: What is the name of the surgical management of right-sided infective endocarditis?

Output: Akinosoglou K, Apostolakis E, Koutsogiannis N, Leivaditis V , Gogos CA. Right-sided infective endocarditis: surgical management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the surgical management of right-sided infective endocarditis?. ### Response: Akinosoglou K, Apostolakis E, Koutsogiannis N, Leivaditis V , Gogos CA. Right-sided infective endocarditis: surgical management.


Instruction: What type of surgery can cause brain damage after open heart surgery in patients with acute cardioembolic stroke?

Output: Valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery can cause brain damage after open heart surgery in patients with acute cardioembolic stroke?. ### Response: Valve replacement.


Instruction: What year did Stroke. 1989:20:1305-1310?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Stroke. 1989:20:1305-1310?. ### Response: 1989.


Instruction: What is the name of the multi-center retrospective study in Japan?

Output: Surgical management of infective endocarditis associated with cere-bral complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-center retrospective study in Japan?. ### Response: Surgical management of infective endocarditis associated with cere-bral complications.


Instruction: What type of endocarditis is associated with cere-bral complications?

Output: infective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of endocarditis is associated with cere-bral complications?. ### Response: infective.


Instruction: What is endocarditis associated with?

Output: cerebrovascular complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is endocarditis associated with?. ### Response: cerebrovascular complications.


Instruction: Where was the multi-center retrospective study conducted?

Output: Japan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the multi-center retrospective study conducted?. ### Response: Japan.


Instruction: What is the name of the study that evaluated brain embolization in patients with left-sided infective endocrine disease?

Output: EMBOLISM) pilot study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated brain embolization in patients with left-sided infective endocrine disease?. ### Response: EMBOLISM) pilot study.


Instruction: What is the name of the pilot study that evaluated the brains of patients with left-sided intracardiac solid masses?

Output: EMBOLISM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pilot study that evaluated the brains of patients with left-sided intracardiac solid masses?. ### Response: EMBOLISM.


Instruction: What is EMBOLISM?

Output: Evaluation by MRI of the Brains of Patients With Left-Sided Intracardiac Solid Masses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EMBOLISM?. ### Response: Evaluation by MRI of the Brains of Patients With Left-Sided Intracardiac Solid Masses.


Instruction: When did Circulation. 2009;120:585–591. doi: 10.1161/CIRCULATIONAHA. 108.834432.264 What is a consideration in timing of surgical intervention for?

Output: infec-tive endocarditis with cerebrovascular complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2009;120:585–591. doi: 10.1161/CIRCULATIONAHA. 108.834432.264 What is a consideration in timing of surgical intervention for?. ### Response: infec-tive endocarditis with cerebrovascular complications.


Instruction: What is the cause of infective endocarditis with cerebrovascular complications?

Output: Surgical management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of infective endocarditis with cerebrovascular complications?. ### Response: Surgical management.


Instruction: When was the J Heart Valve Dis.19:321–325.

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Heart Valve Dis.19:321–325.. ### Response: 2010.


Instruction: What was the neurological outcome of septic cardioembolic stroke after infective endocrinitis?

Output: Subclinical brain embolization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the neurological outcome of septic cardioembolic stroke after infective endocrinitis?. ### Response: Subclinical brain embolization.


Instruction: What did Stroke. 2006 do?

Output: Neurological outcome of septic cardioembolic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Stroke. 2006 do?. ### Response: Neurological outcome of septic cardioembolic stroke.


Instruction: What type of complications are common in patients with left-sided infective endocarditis?

Output: Cerebrovascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of complications are common in patients with left-sided infective endocarditis?. ### Response: Cerebrovascular.


Instruction: What is the name of the prospective study using magnetic resonance imaging and neurochemical brain damage markers?

Output: EMBOLISM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study using magnetic resonance imaging and neurochemical brain damage markers?. ### Response: EMBOLISM.


Instruction: What are neurochemical brain damage markers?

Output: magnetic resonance imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are neurochemical brain damage markers?. ### Response: magnetic resonance imaging.


Instruction: What does Clin Infect Dis. 2008:47:23–30?

Output: a prospective study using magnetic resonance imaging and neurochemical brain damage markers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Clin Infect Dis. 2008:47:23–30?. ### Response: a prospective study using magnetic resonance imaging and neurochemical brain damage markers.


Instruction: What is the population entering the model?

Output: those presenting to primary care with signs and symptom s of heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population entering the model?. ### Response: those presenting to primary care with signs and symptom s of heart failure.


Instruction: What are signs and symptom s of heart failure?

Output: breathlessness, fatigue or ankle swelling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are signs and symptom s of heart failure?. ### Response: breathlessness, fatigue or ankle swelling.


Instruction: Who suspects the patient has heart failure upon clinical examination?

Output: general practitioner

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who suspects the patient has heart failure upon clinical examination?. ### Response: general practitioner.


Instruction: What is the acronym for myocardial infarction?

Output: MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for myocardial infarction?. ### Response: MI.


Instruction: What did the NICE 2010 Chronic Heart Failure guideline state patients with a previous history of?

Output: myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the NICE 2010 Chronic Heart Failure guideline state patients with a previous history of?. ### Response: myocardial infarction.


Instruction: The committee decided that echocardiography without a natriuretic peptide test was no longer appropriate because of what?

Output: the definition of MI has changed over time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee decided that echocardiography without a natriuretic peptide test was no longer appropriate because of what?. ### Response: the definition of MI has changed over time.


Instruction: What did the Mant et al. 2009 HTA form the basis of?

Output: the recommendation in the 2010 guideline212

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Mant et al. 2009 HTA form the basis of?. ### Response: the recommendation in the 2010 guideline212.


Instruction: What was the basis for the recommendation in the 2010 guideline212?

Output: Mant et al. 2009 HTA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the basis for the recommendation in the 2010 guideline212?. ### Response: Mant et al. 2009 HTA.


Instruction: How many increments were downgraded if the majority of the evidence was at high risk of bias?

Output: 1 increment if the majority of the evidence was at high risk of bias , and downgraded b y 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were downgraded if the majority of the evidence was at high risk of bias?. ### Response: 1 increment if the majority of the evidence was at high risk of bias , and downgraded b y 2.


Instruction: What is the name of the book that treats heart failure chronic heart failure?

Output: NICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that treats heart failure chronic heart failure?. ### Response: NICE.


Instruction: How many increments were downgraded if the majority of the evidence was at very high risk of bias?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were downgraded if the majority of the evidence was at very high risk of bias?. ### Response: 2.


Instruction: Why were the downgrade increments?

Output: if the majority of the evidence was at very high risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were the downgrade increments?. ### Response: if the majority of the evidence was at very high risk of bias.


Instruction: People were already enrolled in what?

Output: intrathoracic impedance monitoring device tria l). (c) Downgraded by 1 increment if the confidence interval crossed 1 MID or by 2 increments if the confidence interval crossed both MIDs.  (d) Downgraded by 2 increments because the majority of evidence was from an indirect population ( people were already enrolled in a intrathoracic impedance monitoring device trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People were already enrolled in what?. ### Response: intrathoracic impedance monitoring device tria l). (c) Downgraded by 1 increment if the confidence interval crossed 1 MID or by 2 increments if the confidence interval crossed both MIDs.  (d) Downgraded by 2 increments because the majority of evidence was from an indirect population ( people were already enrolled in a intrathoracic impedance monitoring device trial.


Instruction: Who was already enrolled in a intrathoracic impedance monitoring device tria l?

Output: people

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was already enrolled in a intrathoracic impedance monitoring device tria l?. ### Response: people.


Instruction: Why was the confidence interval downgraded by 2 increments?

Output: people were already enrolled in a intrathoracic impedance monitoring device trial ) and was looking at congestion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the confidence interval downgraded by 2 increments?. ### Response: people were already enrolled in a intrathoracic impedance monitoring device trial ) and was looking at congestion.


Instruction: What was the majority of evidence from?

Output: indirect population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the majority of evidence from?. ### Response: indirect population.


Instruction: How many increments were there because the majority of evidence was from an indirect population?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were there because the majority of evidence was from an indirect population?. ### Response: 2.


Instruction: What is the protocol outcome?

Output: oedema

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the protocol outcome?. ### Response: oedema.


Instruction: What was the risk of IS in the Guidelines for Prevention of Stroke in Women 1573?

Output: RR, 0.70; 95% CI, 0.49–1.00

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of IS in the Guidelines for Prevention of Stroke in Women 1573?. ### Response: RR, 0.70; 95% CI, 0.49–1.00.


Instruction: How was the benefit reduced when the combination of IS and hemorrhagic stroke was considered?

Output: how-ever

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the benefit reduced when the combination of IS and hemorrhagic stroke was considered?. ### Response: how-ever.


Instruction: What is the CI of aspirin?

Output: 0.63–0.93

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CI of aspirin?. ### Response: 0.63–0.93.


Instruction: What is recommended for primary prevention for women after con-sideration of the 10-year risk of CVD and whether this outweighs the risk of hemorrhage?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for primary prevention for women after con-sideration of the 10-year risk of CVD and whether this outweighs the risk of hemorrhage?. ### Response: aspirin.


Instruction: What did aspirin for primary prevention of IS do?

Output: separate from other cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did aspirin for primary prevention of IS do?. ### Response: separate from other cardiovascular events.


Instruction: What did men show no benefit from?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did men show no benefit from?. ### Response: aspirin.


Instruction: For heart disease, men benefited from what?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For heart disease, men benefited from what?. ### Response: aspirin.


Instruction: What did women take aspirin for?

Output: primary prevention for women after con-sideration of the 10-year risk of CVD and whether this and age outweigh the risk of hemorrhage.21A large, sex-specific meta-analysis of aspirin for primary prevention of IS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did women take aspirin for?. ### Response: primary prevention for women after con-sideration of the 10-year risk of CVD and whether this and age outweigh the risk of hemorrhage.21A large, sex-specific meta-analysis of aspirin for primary prevention of IS.


Instruction: What was the reason for the increase in the risk of hemorrhagic stroke and major gastrointestinal and extracranial bleeds among women?

Output: aspirin allocation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reason for the increase in the risk of hemorrhagic stroke and major gastrointestinal and extracranial bleeds among women?. ### Response: aspirin allocation.


Instruction: No evidence of a differential effect of antiplate-let agents for secondary stroke in women compared with men?

Output: men showed no benefit (OR, 1.00; 95% CI, 0.72–1.41).436

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No evidence of a differential effect of antiplate-let agents for secondary stroke in women compared with men?. ### Response: men showed no benefit (OR, 1.00; 95% CI, 0.72–1.41).436.


Instruction: The Antithrombotic Trialists meta-analysis of aspirin for the primary and secondary prevention of vascu-lar events included individual patient data from which trials?

Output: each of the trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Antithrombotic Trialists meta-analysis of aspirin for the primary and secondary prevention of vascu-lar events included individual patient data from which trials?. ### Response: each of the trials.


Instruction: What was found to be similar for men and women for the com-bined outcome?

Output: pro-portional reductions in risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to be similar for men and women for the com-bined outcome?. ### Response: pro-portional reductions in risk.


Instruction: What was the trend toward benefit for primary prevention in women versus men when the P value was adjusted?

Output: no longer the case

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the trend toward benefit for primary prevention in women versus men when the P value was adjusted?. ### Response: no longer the case.


Instruction: What did aspirin have a greater absolute benefit for in secondary prevention?

Output: stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did aspirin have a greater absolute benefit for in secondary prevention?. ### Response: stroke prevention.


Instruction: What was the reduction in stroke incidence for women and men?

Output: 19%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in stroke incidence for women and men?. ### Response: 19%.


Instruction: When was the P value adjusted for multiple comparison?

Output: 0.05); how-ever, the benefit was reduced when the combination of IS and hemorrhagic stroke was considered (RR, 0.78; 95% CI, 0.57–1.08; P=0.13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the P value adjusted for multiple comparison?. ### Response: 0.05); how-ever, the benefit was reduced when the combination of IS and hemorrhagic stroke was considered (RR, 0.78; 95% CI, 0.57–1.08; P=0.13.


Instruction: What is the effect for women and men?

Output: 19% reduction in stroke risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect for women and men?. ### Response: 19% reduction in stroke risk.


Instruction: How much reduction in stroke risk for women?

Output: 19%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much reduction in stroke risk for women?. ### Response: 19%.


Instruction: What is needed to be included in sufficient numbers for preplanned subgroup analysis?

Output: women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to be included in sufficient numbers for preplanned subgroup analysis?. ### Response: women.


Instruction: What is subgroup analysis able to test for?

Output: sex inter -action

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is subgroup analysis able to test for?. ### Response: sex inter -action.


Instruction: What remains unanswered about the benefits and risks of carotid procedures in women with asymptomatic high-grade stenosis?

Output: Questions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains unanswered about the benefits and risks of carotid procedures in women with asymptomatic high-grade stenosis?. ### Response: Questions.


Instruction: What remains unanswered?

Output: Questions about the benefits and risks of carotid procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains unanswered?. ### Response: Questions about the benefits and risks of carotid procedures.


Instruction: What are the recommendations for prevention of stroke in women with carotid disease?

Output: Summary and Gaps

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for prevention of stroke in women with carotid disease?. ### Response: Summary and Gaps.


Instruction: What does the AHA publish for women?

Output: Effectiveness-Based Guidelines for the Prevention of Cardiovascular Disease in Women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the AHA publish for women?. ### Response: Effectiveness-Based Guidelines for the Prevention of Cardiovascular Disease in Women.


Instruction: What are the recommendations for women published in?

Output: Guidelines for Prevention of Stroke in Women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for women published in?. ### Response: Guidelines for Prevention of Stroke in Women.


Instruction: What drugs are widely used for the most common arrhythmias?

Output: A V nodal–blocking drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drugs are widely used for the most common arrhythmias?. ### Response: A V nodal–blocking drugs.


Instruction: What is reasonable for ongoing management in patients with junctional tachycardia?

Output: Oral diltiazem or verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for ongoing management in patients with junctional tachycardia?. ### Response: Oral diltiazem or verapamil.


Instruction: What is often used as first-line chronic therapy for junctional tachycardia?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often used as first-line chronic therapy for junctional tachycardia?. ### Response: Beta blockers.


Instruction: Why are beta blockers often used?

Output: important proarrhythmic effects and long-term toxicity of other agents that have been shown to be effective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are beta blockers often used?. ### Response: important proarrhythmic effects and long-term toxicity of other agents that have been shown to be effective.


Instruction: What should be directed toward avoiding when beta-blocker therapy?

Output: bradyarrhythmias and hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be directed toward avoiding when beta-blocker therapy?. ### Response: bradyarrhythmias and hypotension.


Instruction: What can be avoided when beta-blocker therapy is initiated?

Output: bradyarrhythmias and hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be avoided when beta-blocker therapy is initiated?. ### Response: bradyarrhythmias and hypotension.


Instruction: Diltiazem and verapamil may be suppressed as effectively by what?

Output: beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diltiazem and verapamil may be suppressed as effectively by what?. ### Response: beta blockers.


Instruction: What is suppressed as effectively by diltiazem and verapamil as by beta blockers?

Output: Junctional tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is suppressed as effectively by diltiazem and verapamil as by beta blockers?. ### Response: Junctional tachycardia.


Instruction: What was not induced by atrial or ventricular overdrive pacing, programmed electrical stimulation, or isoproterenol?

Output: junctional tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not induced by atrial or ventricular overdrive pacing, programmed electrical stimulation, or isoproterenol?. ### Response: junctional tachycardia.


Instruction: What is less known about oral diltiazem than verapamil?

Output: it likely has a similar efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less known about oral diltiazem than verapamil?. ### Response: it likely has a similar efficacy.


Instruction: What may be reasonable for ongoing management in patients without structural heart disease or ischemic heart disease?

Output: Flecainide or propafenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable for ongoing management in patients without structural heart disease or ischemic heart disease?. ### Response: Flecainide or propafenone.


Instruction: Who has junctional tachycardia?

Output: mic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has junctional tachycardia?. ### Response: mic heart disease.


Instruction: What was given for acute control?

Output: intravenous flecainide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was given for acute control?. ### Response: intravenous flecainide.


Instruction: How was flecainide given for chronic oral therapy?

Output: intravenous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was flecainide given for chronic oral therapy?. ### Response: intravenous.


Instruction: What is the only data for propafenone stem from case series in infants and children?

Output: 398

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only data for propafenone stem from case series in infants and children?. ### Response: 398.


Instruction: What does flecainide reduce from the ectopic focus in the AV junction?

Output: automaticity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does flecainide reduce from the ectopic focus in the AV junction?. ### Response: automaticity.


Instruction: What may be reasonable in patients with junctional tachycardia when medical therapy is not effective or contraindicated?

Output: Catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable in patients with junctional tachycardia when medical therapy is not effective or contraindicated?. ### Response: Catheter ablation.


Instruction: Radiofrequency ablation has been performed as a potentially curative therapy for what?

Output: junctional tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Radiofrequency ablation has been performed as a potentially curative therapy for what?. ### Response: junctional tachycardia.


Instruction: Since when has catheter ablation been used as a potentially curative therapy for junctional tachycardia?

Output: early 1990s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Since when has catheter ablation been used as a potentially curative therapy for junctional tachycardia?. ### Response: early 1990s.


Instruction: What is the risk of AV block?

Output: 5% to 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of AV block?. ### Response: 5% to 10%.


Instruction: Who uses cryoablation as an alternative to radiofrequency ablation?

Output: practitioners

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who uses cryoablation as an alternative to radiofrequency ablation?. ### Response: practitioners.


Instruction: The initial working document included all topics of interest to what group?

Output: theWork Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The initial working document included all topics of interest to what group?. ### Response: theWork Group.


Instruction: The inclusive, combined set of questionsformed the basis for what?

Output: deliberation and discussion thatfollowed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The inclusive, combined set of questionsformed the basis for what?. ### Response: deliberation and discussion thatfollowed.


Instruction: What did the Work Group strive to ensure were addressed?

Output: all topicsdeemed clinically relevant and worthy of review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group strive to ensure were addressed?. ### Response: all topicsdeemed clinically relevant and worthy of review.


Instruction: What criteria were questions of interest formulated according to?

Output: PICODD (Population, Intervention, Comparator, Outcome,study Design and Duration of follow-up) criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria were questions of interest formulated according to?. ### Response: PICODD (Population, Intervention, Comparator, Outcome,study Design and Duration of follow-up) criteria.


Instruction: What are the details of the criteria presented in Table 5?

Output: Ranking of outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the details of the criteria presented in Table 5?. ### Response: Ranking of outcomes.


Instruction: How did the Work Group rank outcomes of interest?

Output: their importance for informing clinical decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the Work Group rank outcomes of interest?. ### Response: their importance for informing clinical decision making.


Instruction: What is the basis of their importance for informing clinical decision making?

Output: The Work Group ranked outcomes of interest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the basis of their importance for informing clinical decision making?. ### Response: The Work Group ranked outcomes of interest.


Instruction: What was upgraded from ‘high’ to ‘critical’ importance in studies where the baseline GFR was o60 ml/min/1.73 m2(or the SCr was42 mg/dl [ 4177mmol/l]?

Output: Doubling of SCr level or halving of GFR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was upgraded from ‘high’ to ‘critical’ importance in studies where the baseline GFR was o60 ml/min/1.73 m2(or the SCr was42 mg/dl [ 4177mmol/l]?. ### Response: Doubling of SCr level or halving of GFR.


Instruction: What did the Work Group seek to build on from the previous KDOQI Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease?

Output: evidence base

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group seek to build on from the previous KDOQI Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease?. ### Response: evidence base.


Instruction: How was the KDOQI guideline conducted?

Output: inTable 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the KDOQI guideline conducted?. ### Response: inTable 5.


Instruction: What is the CKD ND?

Output: CKD 1– 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CKD ND?. ### Response: CKD 1– 5.


Instruction: How long is the median follow-up for blood pressure?

Output: 6 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the median follow-up for blood pressure?. ### Response: 6 weeks.


Instruction: How long for proteinuria?

Output: 3 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long for proteinuria?. ### Response: 3 months.


Instruction: What is the minimum duration of follow up for other outcomes?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the minimum duration of follow up for other outcomes?. ### Response: 1 year.


Instruction: How long does pressure last for proteinuria?

Output: 3 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does pressure last for proteinuria?. ### Response: 3 months.


Instruction: How long for other outcomes?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long for other outcomes?. ### Response: 1 year.


Instruction: What is CKD ND?

Output: CKD 1– 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD ND?. ### Response: CKD 1– 5.


Instruction: What is CKD T?

Output: kidney-transplant recipient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CKD T?. ### Response: kidney-transplant recipient.


Instruction: How long is the duration of follow-up for proteinuria?

Output: 3 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the duration of follow-up for proteinuria?. ### Response: 3 months.


Instruction: What is the name of the kidney transplant recipient?

Output: CKD T

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the kidney transplant recipient?. ### Response: CKD T.


Instruction: What is the duration of follow-up for proteinuria?

Output: 3 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the duration of follow-up for proteinuria?. ### Response: 3 months.


Instruction: What type of agent is used to treat hypertension?

Output: anti-hypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of agent is used to treat hypertension?. ### Response: anti-hypertensive.


Instruction: What does CKD T stand for?

Output: kidney-transplant recipient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CKD T stand for?. ### Response: kidney-transplant recipient.


Instruction: What is an anti-hypertensive agent?

Output: single or in combination, any dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an anti-hypertensive agent?. ### Response: single or in combination, any dose.


Instruction: What is the highest risk for adverse outcomes from IE?

Output: cardiac valve repair with a prosthetic valve or prosthetic material

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the highest risk for adverse outcomes from IE?. ### Response: cardiac valve repair with a prosthetic valve or prosthetic material.


Instruction: What is a reasonable prophylaxis before high-risk dental procedures?

Output: antibiotic drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable prophylaxis before high-risk dental procedures?. ### Response: antibiotic drugs.


Instruction: What is the term for unrepaired cyanotic CHD?

Output: cer -tain CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for unrepaired cyanotic CHD?. ### Response: cer -tain CHD.


Instruction: What is another term for recipients of cardiac transplants who develop cardiac valvulopathy?

Output: cer -tain CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for recipients of cardiac transplants who develop cardiac valvulopathy?. ### Response: cer -tain CHD.


Instruction: What are recipients of cardiac transplants who develop?

Output: cardiac valvulopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are recipients of cardiac transplants who develop?. ### Response: cardiac valvulopathy.


Instruction: What will continue to be reiterated as part of their healthcare maintenance program?

Output: IE prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will continue to be reiterated as part of their healthcare maintenance program?. ### Response: IE prevention.


Instruction: Children with cyanosis may have specific what?

Output: periodon-tal concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Children with cyanosis may have specific what?. ### Response: periodon-tal concerns.


Instruction: What type of concerns may children with cyanosis have?

Output: periodon-tal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of concerns may children with cyanosis have?. ### Response: periodon-tal.


Instruction: Who recommends that prophylactic antibiotic drugs be considered before certain dental procedures?

Output: The AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who recommends that prophylactic antibiotic drugs be considered before certain dental procedures?. ### Response: The AHA.


Instruction: What is considered3 (Class IIb; Level of Evidence C)?

Output: prophylactic antibiotic drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered3 (Class IIb; Level of Evidence C)?. ### Response: prophylactic antibiotic drugs.


Instruction: Echocardiographic Features Suggesting Potential Need for Surgical Intervention What type of vegetation after systemic embolization?

Output: Persistent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Echocardiographic Features Suggesting Potential Need for Surgical Intervention What type of vegetation after systemic embolization?. ### Response: Persistent.


Instruction: What type of events occur during or after antimicrobial therapy?

Output: Embolic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of events occur during or after antimicrobial therapy?. ### Response: Embolic.


Instruction: Increase in vegetation size after 4 wk of what?

Output: antimicrobial therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Increase in vegetation size after 4 wk of what?. ### Response: antimicrobial therapy.


Instruction: Valvular dysfunction Acute aortic or mitral insufficiency with signs of what type of failure?

Output: ventricular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Valvular dysfunction Acute aortic or mitral insufficiency with signs of what type of failure?. ### Response: ventricular.


Instruction: What may be required because of risk of recurrent embolization?

Output: Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be required because of risk of recurrent embolization?. ### Response: Surgery.


Instruction: What may be required because of risk of embolization?

Output: Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be required because of risk of embolization?. ### Response: Surgery.


Instruction: What is the reason that surgery may be necessary because of heart failure?

Output: failure of medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reason that surgery may be necessary because of heart failure?. ### Response: failure of medical therapy.


Instruction: What is the name of the person who works for the Mayo Clinic?

Output: Larry M. Baddour

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who works for the Mayo Clinic?. ### Response: Larry M. Baddour.


Instruction: What is another name for an expert witness?

Output: Bureau/Honoraria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for an expert witness?. ### Response: Bureau/Honoraria.


Instruction: What is the name of the Children’s Hospital of Pittsburgh?

Output: Lee B. Beerman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Children’s Hospital of Pittsburgh?. ### Response: Lee B. Beerman.


Instruction: What is another name for the Children's Mercy Hospital?

Output: Mary Anne Jackson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the Children's Mercy Hospital?. ### Response: Mary Anne Jackson.


Instruction: How much adenosine is needed in chil-dren than in adults?

Output: Higher initial doses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much adenosine is needed in chil-dren than in adults?. ### Response: Higher initial doses.


Instruction: What is the recommended initial dose for children with SVT?

Output: 150 mcg/kg  to 250 mcg/kg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended initial dose for children with SVT?. ### Response: 150 mcg/kg  to 250 mcg/kg.


Instruction: Digoxin and propranolol have simi-lar efficacy in infants without what?

Output: pre-excitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Digoxin and propranolol have simi-lar efficacy in infants without what?. ### Response: pre-excitation.


Instruction: Why is digoxin avoided in the presence of pre-excitation?

Output: its use in infancy has been associated with SCD or ventricu-lar fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is digoxin avoided in the presence of pre-excitation?. ### Response: its use in infancy has been associated with SCD or ventricu-lar fibrillation.


Instruction: What has been associated with SCD or ventricu-lar fibrillation?

Output: Digoxin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been associated with SCD or ventricu-lar fibrillation?. ### Response: Digoxin.


Instruction: Amiodarone, sotalol, propafenone and flecainide can be used for what type of SVT in infants?

Output: refractory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Amiodarone, sotalol, propafenone and flecainide can be used for what type of SVT in infants?. ### Response: refractory.


Instruction: In older children presenting with SVT, beta-blocker therapy is what?

Output: most often the initial therapy used

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In older children presenting with SVT, beta-blocker therapy is what?. ### Response: most often the initial therapy used.


Instruction: What is most often the initial therapy used with SVT?

Output: beta-blocker therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is most often the initial therapy used with SVT?. ### Response: beta-blocker therapy.


Instruction: Why is flecainide not used as a first-line medication in children?

Output: rare occurrence of adverse events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is flecainide not used as a first-line medication in children?. ### Response: rare occurrence of adverse events.


Instruction: What is the first-line medication in children?

Output: adenosine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first-line medication in children?. ### Response: adenosine.


Instruction: What was the patient's heart rate during exercise testing?

Output: 117 bpm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the patient's heart rate during exercise testing?. ### Response: 117 bpm.


Instruction: When the patient lost pre-excitation, the PR interval normalizes and the QRS changes to what?

Output: narrow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When the patient lost pre-excitation, the PR interval normalizes and the QRS changes to what?. ### Response: narrow.


Instruction: How does the QRS change from pre-excited to narrow?

Output: Beginning abruptly with the beat under the arrow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the QRS change from pre-excited to narrow?. ### Response: Beginning abruptly with the beat under the arrow.


Instruction: How does AVRT indicate atrioventricular reentrant tachycardia?

Output: ECG, electrocardiogram

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does AVRT indicate atrioventricular reentrant tachycardia?. ### Response: ECG, electrocardiogram.


Instruction: What does ECG mean?

Output: electrocardiogram

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ECG mean?. ### Response: electrocardiogram.


Instruction: What is ischemic heart disease?

Output: structural heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ischemic heart disease?. ### Response: structural heart disease.


Instruction: When was this article downloaded?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: April 23, 2023.


Instruction: What distinguishes top-performing hospitals in acute myocardial infarction mortality rates?

Output: A qualitative study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What distinguishes top-performing hospitals in acute myocardial infarction mortality rates?. ### Response: A qualitative study.


Instruction: What does Curry LA, Spatz E, Cherlin E, et al. do?

Output: acute myocardial infarction mortality rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Curry LA, Spatz E, Cherlin E, et al. do?. ### Response: acute myocardial infarction mortality rates.


Instruction: When did Ann Intern Med. 2011;154:384–90.632?

Output: January 29, 2013631

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ann Intern Med. 2011;154:384–90.632?. ### Response: January 29, 2013631.


Instruction: What is the association between timeliness of reperfusion therapy and clinical outcomes in ST-elevation myocardial infarction?

Output: Door-to-balloon times under 90 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between timeliness of reperfusion therapy and clinical outcomes in ST-elevation myocardial infarction?. ### Response: Door-to-balloon times under 90 min.


Instruction: When was the STREAM Trial conducted?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the STREAM Trial conducted?. ### Response: 2011.


Instruction: What was the ClinicalTrials.gov identifier?

Output: NCT00623623

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the ClinicalTrials.gov identifier?. ### Response: NCT00623623.


Instruction: How many patients were treated with primary percutaneous coronary intervention, in-hospital thrombolysis and prehospital thombolysis?

Output: 625

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with primary percutaneous coronary intervention, in-hospital thrombolysis and prehospital thombolysis?. ### Response: 625.


Instruction: What was the outcome of the observational study?

Output: 625 patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the observational study?. ### Response: 625 patients.


Instruction: When was the Emerg Med J.28:230–6.635?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Emerg Med J.28:230–6.635?. ### Response: 2011.


Instruction: How long are door-to-balloon times?

Output: under 90 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long are door-to-balloon times?. ### Response: under 90 min.


Instruction: What can be achieved for patients transferred for ST-segment elevation myocardial infarction percutaneous coronary interven-tion in a rural setting?

Output: Door-to-balloon times under 90 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be achieved for patients transferred for ST-segment elevation myocardial infarction percutaneous coronary interven-tion in a rural setting?. ### Response: Door-to-balloon times under 90 min.


Instruction: What is the J Am Coll Cardiol. 2011;57:272–9.636?

Output: Door-to-balloon times under 90 min can be routinely achieved for patients transferred for ST-segment elevation myocardial infarction percutaneous coronary interven-tion in a rural setting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2011;57:272–9.636?. ### Response: Door-to-balloon times under 90 min can be routinely achieved for patients transferred for ST-segment elevation myocardial infarction percutaneous coronary interven-tion in a rural setting.


Instruction: How long can door-to-balloon times be achieved?

Output: under 90 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long can door-to-balloon times be achieved?. ### Response: under 90 min.


Instruction: What is the name of the trial in which genetic variants in ABCB1 and CYP2C19 are linked to cardiovascular outcomes?

Output: TRITON-TIMI 38

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial in which genetic variants in ABCB1 and CYP2C19 are linked to cardiovascular outcomes?. ### Response: TRITON-TIMI 38.


Instruction: What is clopidogrel and prasugrel used in?

Output: TRITON-TIMI 38 trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel and prasugrel used in?. ### Response: TRITON-TIMI 38 trial.


Instruction: What was the name of the pharmacogenetic analysis of clopidogrel and prasugrel in the TRITON-TIMI 38 trial?

Output: Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the pharmacogenetic analysis of clopidogrel and prasugrel in the TRITON-TIMI 38 trial?. ### Response: Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes.


Instruction: When did the Lancet issue 376:1312–9.638?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet issue 376:1312–9.638?. ### Response: 2010.


Instruction: What is a thrombin-receptor antagonist in acute coronary syndrome?

Output: vora-paxar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a thrombin-receptor antagonist in acute coronary syndrome?. ### Response: vora-paxar.


Instruction: What is the name of the thrombin-receptor antagonist used in acute coronary syndromes?

Output: vora-paxar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the thrombin-receptor antagonist used in acute coronary syndromes?. ### Response: vora-paxar.


Instruction: What are the underlying pathophysiology and clinical diagnosis of microvascular obstruction?

Output: Microvascular obstruc-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the underlying pathophysiology and clinical diagnosis of microvascular obstruction?. ### Response: Microvascular obstruc-tion.


Instruction: When was the J Am Coll Car -diol published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Car -diol published?. ### Response: 2011.


Instruction: What drug reduces in-farct size and improves cardiac function in a porcine model of ischemia and reperfusion injury?

Output: Exenatide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug reduces in-farct size and improves cardiac function in a porcine model of ischemia and reperfusion injury?. ### Response: Exenatide.


Instruction: What is the name of the drug that reduces the size of infarcting in ischemic and repefusion injury in porcine models?

Output: Exenatide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that reduces the size of infarcting in ischemic and repefusion injury in porcine models?. ### Response: Exenatide.


Instruction: How does the drug exenatide improve cardiac function?

Output: reduces in-farct size and improves cardiac function in a porcine model of ischemia and reperfusion injury

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the drug exenatide improve cardiac function?. ### Response: reduces in-farct size and improves cardiac function in a porcine model of ischemia and reperfusion injury.


Instruction: When did Wu KC say that he is fighting the “fire” of myocardial reperial injury: how do you define success?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Wu KC say that he is fighting the “fire” of myocardial reperial injury: how do you define success?. ### Response: 2009.


Instruction: What is the name of the journal in which success is defined?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal in which success is defined?. ### Response: JAMA.


Instruction: What is a side effect of reperfusion injury, microvas-cular dysfunction, and cardioprotection?

Output: dark side

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a side effect of reperfusion injury, microvas-cular dysfunction, and cardioprotection?. ### Response: dark side.


Instruction: In what year did Circulation issue 120:2105–12.645?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Circulation issue 120:2105–12.645?. ### Response: 2009.


Instruction: How is statin used in patients undergoing percutaneous coronary intervention?

Output: pre-treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is statin used in patients undergoing percutaneous coronary intervention?. ### Response: pre-treatment.


Instruction: What is the benefit of statin pre-treatment in patients undergoing percutaneous coronary intervention?

Output: Clinical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of statin pre-treatment in patients undergoing percutaneous coronary intervention?. ### Response: Clinical.


Instruction: How many randomized studies were included in the collaborative patient-level meta-analysis?

Output: 13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized studies were included in the collaborative patient-level meta-analysis?. ### Response: 13.


Instruction: What ischaemia can cause chest pain?

Output: myocardial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What ischaemia can cause chest pain?. ### Response: myocardial.


Instruction: When was the data based on?

Output: 19 79

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the data based on?. ### Response: 19 79.


Instruction: What is the UK population?

Output: whole population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the UK population?. ### Response: whole population.


Instruction: What is applicable t o cont emporar y UK populations?

Output: Any trials should also in vestigat e the feasibility of intr oducing a suggest ed guideline protocol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is applicable t o cont emporar y UK populations?. ### Response: Any trials should also in vestigat e the feasibility of intr oducing a suggest ed guideline protocol.


Instruction: What remain continuing uncer tainties about the initial assessment of people wit h suspected stable angina?

Output: Ther e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remain continuing uncer tainties about the initial assessment of people wit h suspected stable angina?. ### Response: Ther e.


Instruction: What is an example of a routine blood mark er?

Output: haemoglobin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a routine blood mark er?. ### Response: haemoglobin.


Instruction: What is a novel cir culating biomark er to estimate the pr e-test likelihood of CAD?

Output: CG95

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a novel cir culating biomark er to estimate the pr e-test likelihood of CAD?. ### Response: CG95.


Instruction: What is ther assessment in t he whole population and in pr edefined subgr oups including et hnic minorities?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ther assessment in t he whole population and in pr edefined subgr oups including et hnic minorities?. ### Response: age.


Instruction: 4 Informa tion abou t presen ting and e xplaining tests All people pr senting wit h chest pain will need to decide whet she ts to accept?

Output: t he diagnostic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 4 Informa tion abou t presen ting and e xplaining tests All people pr senting wit h chest pain will need to decide whet she ts to accept?. ### Response: t he diagnostic.


Instruction: What should a woman do to accept t he diagnostic and car e pat hways offered?

Output: decide whet her t o accept t he diagnostic and car e pat hways off ered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a woman do to accept t he diagnostic and car e pat hways offered?. ### Response: decide whet her t o accept t he diagnostic and car e pat hways off ered.


Instruction: What should be most eff ectively present?

Output: par ticular gr oups of people

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be most eff ectively present?. ### Response: par ticular gr oups of people.


Instruction: What should be most eff ectively present ed to par ticular gr oups of people, defined b y age, et hnicity and se x?

Output: wit hout tr eatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be most eff ectively present ed to par ticular gr oups of people, defined b y age, et hnicity and se x?. ### Response: wit hout tr eatment.


Instruction: What will be guided by the cont ent and deliv ery?

Output: Methods of communication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will be guided by the cont ent and deliv ery?. ### Response: Methods of communication.


Instruction: What will be guided b y curr ent evidence-based best practice?

Output: Methods of communication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will be guided b y curr ent evidence-based best practice?. ### Response: Methods of communication.


Instruction: Contr olled trials should be conduct ed based on what?

Output: w ell-construct ed randomised contr olled clinical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Contr olled trials should be conduct ed based on what?. ### Response: w ell-construct ed randomised contr olled clinical trials.


Instruction: What should be included in a study of chest pain?

Output: the feasibility of intr oducing a suggest ed guideline protocol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be included in a study of chest pain?. ### Response: the feasibility of intr oducing a suggest ed guideline protocol.


Instruction: What is a common mechanism for chest pain studies?

Output: advice and discussion with a clinician or a specialist nurse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common mechanism for chest pain studies?. ### Response: advice and discussion with a clinician or a specialist nurse.


Instruction: What should any trials also in vestigate the feasibility of intr oducing a suggest ed guideline protocol to be used with all people?

Output: randomised contr olled clinical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should any trials also in vestigate the feasibility of intr oducing a suggest ed guideline protocol to be used with all people?. ### Response: randomised contr olled clinical trials.


Instruction: What should all people pr esent wit h chest pain when f aced wit options concerning t heir clinical pat hway?

Output: Any trials should also in vestigat e the feasibility of intr oducing a suggest ed guideline protocol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all people pr esent wit h chest pain when f aced wit options concerning t heir clinical pat hway?. ### Response: Any trials should also in vestigat e the feasibility of intr oducing a suggest ed guideline protocol.


Instruction: How can a healt hcare professional be r easonably cer tain t hat inf ormed consent has been obtained?

Output: b y clearly e xplaining and t hen discussing t he pr oposed diagnostic and car e pat hways

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can a healt hcare professional be r easonably cer tain t hat inf ormed consent has been obtained?. ### Response: b y clearly e xplaining and t hen discussing t he pr oposed diagnostic and car e pat hways.


Instruction: What should be giv en to any communication that oblems t he person?

Output: Consideration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be giv en to any communication that oblems t he person?. ### Response: Consideration.


Instruction: What should a patient's moral, et hical, and spiritual beliefs, expectations, and an y misconceptions about their condition be considered?

Output: any communication pr oblems t he person ma y have

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient's moral, et hical, and spiritual beliefs, expectations, and an y misconceptions about their condition be considered?. ### Response: any communication pr oblems t he person ma y have.


Instruction: What is the name of the document that describes recent onset chest pain of suspect ed car diac origin?

Output: CG95

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that describes recent onset chest pain of suspect ed car diac origin?. ### Response: CG95.


Instruction: When is NICE 2022?

Output: Recent -onset chest pain of suspect ed car diac origin: assessment and diagnosis (CG95)© NICE 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is NICE 2022?. ### Response: Recent -onset chest pain of suspect ed car diac origin: assessment and diagnosis (CG95)© NICE 2022.


Instruction: What was the last updat ed 30 No vember 2016Page 26of 33?

Output: Notice of right s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the last updat ed 30 No vember 2016Page 26of 33?. ### Response: Notice of right s.


Instruction: How long after PCI did patients ask questions about their medications?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after PCI did patients ask questions about their medications?. ### Response: 6 months.


Instruction: What is a NCQA-HCAHPS?

Output: Hospital Consumer Assessment ofHealthcare Providers and Systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a NCQA-HCAHPS?. ### Response: Hospital Consumer Assessment ofHealthcare Providers and Systems.


Instruction: What are two types of hospital consumer assessment ofhealthcare providers and systems?

Output: PCI case volume –speciﬁcstructural measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two types of hospital consumer assessment ofhealthcare providers and systems?. ### Response: PCI case volume –speciﬁcstructural measures.


Instruction: Many individual hospital systems have devel-oped and implemented diagnosis-related group-basedpostdischarge surveys?

Output: save your life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Many individual hospital systems have devel-oped and implemented diagnosis-related group-basedpostdischarge surveys?. ### Response: save your life.


Instruction: Critics point out that such surveys can be what?

Output: disproportionately weighted by items un-related to care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Critics point out that such surveys can be what?. ### Response: disproportionately weighted by items un-related to care.


Instruction: What can be disproportionately weighted by items un-related to care?

Output: availability of channels on thehospital television, food menu choices, and parking con-venience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be disproportionately weighted by items un-related to care?. ### Response: availability of channels on thehospital television, food menu choices, and parking con-venience.


Instruction: What do critics point out that standardized tools for symptommeasurement and for patient subsets are lacking?

Output: existing standards encourage reporting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do critics point out that standardized tools for symptommeasurement and for patient subsets are lacking?. ### Response: existing standards encourage reporting.


Instruction: What does the writing committee believe?

Output: these structural measures can provide important contribu-tions to the assessment of care equity and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing committee believe?. ### Response: these structural measures can provide important contribu-tions to the assessment of care equity and safety.


Instruction: What does not exist for patient survey data?

Output: validated risk-adjustment models

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not exist for patient survey data?. ### Response: validated risk-adjustment models.


Instruction: What does not exist in the present document?

Output: validated risk-adjustment models for patient survey data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not exist in the present document?. ### Response: validated risk-adjustment models for patient survey data.


Instruction: What is an important area for futuredevelopment?

Output: patient surveys

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important area for futuredevelopment?. ### Response: patient surveys.


Instruction: What are measures to evaluate process and outcomes more clearly substantiated by?

Output: an evidence base

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are measures to evaluate process and outcomes more clearly substantiated by?. ### Response: an evidence base.


Instruction: What is easier toassess than many clinicallyimportant process and outcome measures?

Output: structural measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is easier toassess than many clinicallyimportant process and outcome measures?. ### Response: structural measures.


Instruction: How can one trackchanges longitudinally without needing risk adjustment?

Output: it is easier toassess structural measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can one trackchanges longitudinally without needing risk adjustment?. ### Response: it is easier toassess structural measures.


Instruction: How many measures of structure were included?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many measures of structure were included?. ### Response: 3.


Instruction: What is the only measure of quality improvement?

Output: annual operator PCI volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only measure of quality improvement?. ### Response: annual operator PCI volume.


Instruction: How many measure of structure did we include?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many measure of structure did we include?. ### Response: 3.


Instruction: What measure is the annual hospital PCIvolume?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What measure is the annual hospital PCIvolume?. ### Response: 11.


Instruction: What does the PCI case volume -specificstructural measures encourage reporting?

Output: data collection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the PCI case volume -specificstructural measures encourage reporting?. ### Response: data collection.


Instruction: What has the experience of the operator and hospital performing PCI been associated with?

Output: improved outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has the experience of the operator and hospital performing PCI been associated with?. ### Response: improved outcomes.


Instruction: What is the intent of the case-volume measures?

Output: to encourage data collection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the intent of the case-volume measures?. ### Response: to encourage data collection.


Instruction: What are the case volume measures intended to encourage rather than specific targets?

Output: data collection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the case volume measures intended to encourage rather than specific targets?. ### Response: data collection.


Instruction: What is the prognostic role of ambulatory blood pressure measurement in patients with nondialysis chronic kidney disease?

Output: reduces cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic role of ambulatory blood pressure measurement in patients with nondialysis chronic kidney disease?. ### Response: reduces cardiovascular risk.


Instruction: What are the results of the MAPEC study?

Output: Inﬂuence of circadian time ofhypertension treatment on cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the MAPEC study?. ### Response: Inﬂuence of circadian time ofhypertension treatment on cardiovascular risk.


Instruction: What is the effect of hypertension treatment on cardiovascular risk?

Output: Inﬂuence of circadian time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of hypertension treatment on cardiovascular risk?. ### Response: Inﬂuence of circadian time.


Instruction: What does ambulatory monitoring reduce?

Output: cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ambulatory monitoring reduce?. ### Response: cardiovascular risk.


Instruction: When did the MAPEC study conclude?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the MAPEC study conclude?. ### Response: 2010.


Instruction: How does bedtime dosing of antihypertensivemedications reduce cardiovascular risk in CKD?

Output: Decreasing sleep-time blood pressuredetermined by ambulatory monitoring reduces cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does bedtime dosing of antihypertensivemedications reduce cardiovascular risk in CKD?. ### Response: Decreasing sleep-time blood pressuredetermined by ambulatory monitoring reduces cardiovascular risk.


Instruction: What is the name of the meta-analysis of compliance, safety, and effectiveness offixed-dose combinations?

Output: Hypertension 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of compliance, safety, and effectiveness offixed-dose combinations?. ### Response: Hypertension 2010.


Instruction: What does ACE inhibitor stand for?

Output: Angiotensin-converting enzyme inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACE inhibitor stand for?. ### Response: Angiotensin-converting enzyme inhibitor.


Instruction: What is the name of the US Food and Drug Administration's public health advisory?

Output: Angiotensin-converting enzyme inhibitor (ACE inhibitor) drugs and pregnancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the US Food and Drug Administration's public health advisory?. ### Response: Angiotensin-converting enzyme inhibitor (ACE inhibitor) drugs and pregnancy.


Instruction: Where can you find a list of public health advisories?

Output: http://www.fda.gov/Drugs/DrugSafety/Pos tmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/PublicHealthAdvisories/ucm053113.htm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find a list of public health advisories?. ### Response: http://www.fda.gov/Drugs/DrugSafety/Pos tmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/PublicHealthAdvisories/ucm053113.htm.


Instruction: How many pages are in the 2003 Proc.?

Output: 16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages are in the 2003 Proc.?. ### Response: 16.