Instruction: What type of article is used to identify clinical trials/SRs/Mas:Filters: Meta-Analysis, Systematic Reviews, Controlled Clinical Trial, Randomized Controlled Trial, Adult: 19+ yearsTerms to identify observational studies:2011/01/01 to 2018/12/31, Humans, English, Epidemiologic Studies, Case-Control Studies, Cohort Studies

Output: newspaper

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of article is used to identify clinical trials/SRs/Mas:Filters: Meta-Analysis, Systematic Reviews, Controlled Clinical Trial, Randomized Controlled Trial, Adult: 19+ yearsTerms to identify observational studies:2011/01/01 to 2018/12/31, Humans, English, Epidemiologic Studies, Case-Control Studies, Cohort Studies. ### Response: newspaper.


Instruction: How old is the adult population?

Output: 19+ years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is the adult population?. ### Response: 19+ years.


Instruction: What is the name of the disease?

Output: Cardiovascular Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease?. ### Response: Cardiovascular Disease.


Instruction: When was the search limited to adult populations?

Output: 01/01/2010-10/3/18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the search limited to adult populations?. ### Response: 01/01/2010-10/3/18.


Instruction: What is an acute coronary syndrome?

Output: Acute coronary syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an acute coronary syndrome?. ### Response: Acute coronary syndromes.


Instruction: What is a myocardial infarction?

Output: Myocardial infarctions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a myocardial infarction?. ### Response: Myocardial infarctions.


Instruction: How many years after left atrial appendage closure did the PREVAIL and PROTECT AF trials last?

Output: 5-Y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years after left atrial appendage closure did the PREVAIL and PROTECT AF trials last?. ### Response: 5-Y.


Instruction: What is the DOI for 2021 Guideline for the Secondary Prevention of Ischemic Stroke?

Output: GUIDELINESKleindorfer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI for 2021 Guideline for the Secondary Prevention of Ischemic Stroke?. ### Response: GUIDELINESKleindorfer.


Instruction: What is the difference between warfarin and percutaneous left atrial appendage closure for atrial fibrillation?

Output: 5-Y ear outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between warfarin and percutaneous left atrial appendage closure for atrial fibrillation?. ### Response: 5-Y ear outcomes.


Instruction: What is a randomized clinical trial of Percutaneous Left Atrial Appendage Closure?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomized clinical trial of Percutaneous Left Atrial Appendage Closure?. ### Response: JAMA.


Instruction: What is the difference between appendage closure and warfarin for atrial fibrillation?

Output: Percutaneous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between appendage closure and warfarin for atrial fibrillation?. ### Response: Percutaneous.


Instruction: When did JAMA issue 312:1988-1998?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 312:1988-1998?. ### Response: 2014.


Instruction: What was the name of the randomized clinical trial?

Output: Percutaneous left atrial appendage closure vs warfarin for atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the randomized clinical trial?. ### Response: Percutaneous left atrial appendage closure vs warfarin for atrial fibrillation.


Instruction: What ischaemic stroke patients with atrial fibrillation receive early antithrombotic therapy?

Output: acute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What ischaemic stroke patients with atrial fibrillation receive early antithrombotic therapy?. ### Response: acute.


Instruction: What are the outcomes associated with apix-aban use in acute stroke patients?

Output: improved outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes associated with apix-aban use in acute stroke patients?. ### Response: improved outcome.


Instruction: When was the Eur J Neurol 22:1048-1055?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur J Neurol 22:1048-1055?. ### Response: 2015.


Instruction: What is apix-aban use associated with in patients with end-stage kidney disease and atrial fibril-lation in the US?

Output: Outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is apix-aban use associated with in patients with end-stage kidney disease and atrial fibril-lation in the US?. ### Response: Outcomes.


Instruction: What is the doi: 10.1161/CIRCULATIONAHA.118.035418 439?

Output: Circulation. 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1161/CIRCULATIONAHA.118.035418 439?. ### Response: Circulation. 2018.


Instruction: Who was selected for antico-agulation: stroke?

Output: patients with atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was selected for antico-agulation: stroke?. ### Response: patients with atrial fibrillation.


Instruction: What is Petersen's title?

Output: Petersen P

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Petersen's title?. ### Response: Petersen P.


Instruction: What is the name of the journal that studies stroke risk stratification in patients taking aspirin?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies stroke risk stratification in patients taking aspirin?. ### Response: JAMA.


Instruction: When was the last issue of Circulation?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of Circulation?. ### Response: 2018.


Instruction: What are the results of the National Registry of Atrial Fibrillation?

Output: Validation of clinical classification schemes for predicting stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the National Registry of Atrial Fibrillation?. ### Response: Validation of clinical classification schemes for predicting stroke.


Instruction: What is the doi: 10.1001/jama.285.22.2864 441.

Output: JAMA. 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1001/jama.285.22.2864 441.. ### Response: JAMA. 2001.


Instruction: What are predictors of atrial fibrillation recurrence in?

Output: hyperthyroid and euthyroid pa-tients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are predictors of atrial fibrillation recurrence in?. ### Response: hyperthyroid and euthyroid pa-tients.


Instruction: What year did Cardiol. 2016:106:84–91?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Cardiol. 2016:106:84–91?. ### Response: 2016.


Instruction: What is the doi: 10.5935/abc.20160013 442.

Output: Arq Bras Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.5935/abc.20160013 442.. ### Response: Arq Bras Cardiol.


Instruction: Incidence of postoperative atrial fibrillation recurrence after cardiac surgery: a systematic review and meta-analysis?

Output: patients dis-charged in sinus rhythm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Incidence of postoperative atrial fibrillation recurrence after cardiac surgery: a systematic review and meta-analysis?. ### Response: patients dis-charged in sinus rhythm.


Instruction: What is likely to recur in the absence of other triggers?

Output: New-onset of postoperative atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to recur in the absence of other triggers?. ### Response: New-onset of postoperative atrial fibrillation.


Instruction: What is Surg. 2018;26:504–511. doi: 10.1093/icvts/ivx348 443.

Output: Interact Cardiovasc Thorac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Surg. 2018;26:504–511. doi: 10.1093/icvts/ivx348 443.. ### Response: Interact Cardiovasc Thorac.


Instruction: What is the name of the 2018 issue of Ther Clin Risk Manag?

Output: 14:1641–1647

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2018 issue of Ther Clin Risk Manag?. ### Response: 14:1641–1647.


Instruction: What are the recurrence rates of atrial fibrillation after success-ful electrical cardioversion in patients with hyperthyroidism-induced vertigo?

Output: Comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recurrence rates of atrial fibrillation after success-ful electrical cardioversion in patients with hyperthyroidism-induced vertigo?. ### Response: Comparison.


Instruction: What can lead to exposure to potentially toxic therapy that could be avoided with earlier pathogen identification?

Output: common bacterial causes of IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can lead to exposure to potentially toxic therapy that could be avoided with earlier pathogen identification?. ### Response: common bacterial causes of IE.


Instruction: What is an evaluation of epidemiological factors including history of prior infections?

Output: Table 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an evaluation of epidemiological factors including history of prior infections?. ### Response: Table 6.


Instruction: What should be done in all IE cases?

Output: An evaluation of epidemiological factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be done in all IE cases?. ### Response: An evaluation of epidemiological factors.


Instruction: What is generally required during the period between the collection of blood cultures and the determination of a pathogen or if blood cultures are ultimately deemed culture negative?

Output: empirical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is generally required during the period between the collection of blood cultures and the determination of a pathogen or if blood cultures are ultimately deemed culture negative?. ### Response: empirical therapy.


Instruction: What type of therapy is generally required?

Output: empirical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is generally required?. ### Response: empirical therapy.


Instruction: Consultation with an infectious diseases specialist is recommended to define the most appropriate choice of what?

Output: therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Consultation with an infectious diseases specialist is recommended to define the most appropriate choice of what?. ### Response: therapy.


Instruction: Collection of additional clinical and laboratory data dictates subsequent revisions in initial empirical therapy that will be administered over the treatment course?

Output: blood culture results or other laboratory methodologies define a pathogen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Collection of additional clinical and laboratory data dictates subsequent revisions in initial empirical therapy that will be administered over the treatment course?. ### Response: blood culture results or other laboratory methodologies define a pathogen.


Instruction: What could be administered over the treatment course?

Output: empirical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be administered over the treatment course?. ### Response: empirical therapy.


Instruction: For patients with acute (days) clinical presentations of native valve infection, what is reasonable coverage?

Output: S aureus, β-hemolytic streptococci, and aerobic Gram-negative bacilli

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients with acute (days) clinical presentations of native valve infection, what is reasonable coverage?. ### Response: S aureus, β-hemolytic streptococci, and aerobic Gram-negative bacilli.


Instruction: What could include vancomycin and cefepime as an initial regimen?

Output: Empirical coverage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could include vancomycin and cefepime as an initial regimen?. ### Response: Empirical coverage.


Instruction: How long is the presentation of NVE?

Output: weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the presentation of NVE?. ### Response: weeks.


Instruction: What is a reasonable coverage of S aureus, VGS, HACEK, and enterococci?

Output: antibiotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable coverage of S aureus, VGS, HACEK, and enterococci?. ### Response: antibiotic therapy.


Instruction: How could one treatment option include vancomycin and ampicillin-sulbactam to provide some coverage for these organisms?

Output: pro-vide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How could one treatment option include vancomycin and ampicillin-sulbactam to provide some coverage for these organisms?. ### Response: pro-vide.


Instruction: When is a pathogen recovered from blood cultures?

Output: subsequent blood culture results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is a pathogen recovered from blood cultures?. ### Response: subsequent blood culture results.


Instruction: What is reasonable for patients with culture-negative PVE if the onset of symptoms is within 1 year of prosthetic valve placement?

Output: coverage for staphylococci, enterococci, and aerobic Gram-negative bacilli

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for patients with culture-negative PVE if the onset of symptoms is within 1 year of prosthetic valve placement?. ### Response: coverage for staphylococci, enterococci, and aerobic Gram-negative bacilli.


Instruction: A regimen could include what?

Output: vanco-mycin, rifampin, gentamicin, and cefepime

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A regimen could include what?. ### Response: vanco-mycin, rifampin, gentamicin, and cefepime.


Instruction: What are the three most common antibiotics for IE?

Output: staphylococci, VGS, and enterococci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the three most common antibiotics for IE?. ### Response: staphylococci, VGS, and enterococci.


Instruction: How long after valve placement is IE most likely to onset?

Output: >1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after valve placement is IE most likely to onset?. ### Response: >1 year.


Instruction: What are two initial treatment options?

Output: vancomycin and ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two initial treatment options?. ### Response: vancomycin and ceftriaxone.


Instruction: If a blood culture results in IE, what should be done?

Output: empirical therapy should be revised to focused therapy that is recommended for the specific pathogen identified

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If a blood culture results in IE, what should be done?. ### Response: empirical therapy should be revised to focused therapy that is recommended for the specific pathogen identified.


Instruction: What are two examples of true culture-negative IE?

Output: Bartonella species, C burnetii, and Brucella species

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two examples of true culture-negative IE?. ### Response: Bartonella species, C burnetii, and Brucella species.


Instruction: What should be revised if subsequent blood culture results or other laboratory methodologies define a pathogen?

Output: empirical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be revised if subsequent blood culture results or other laboratory methodologies define a pathogen?. ### Response: empirical therapy.


Instruction: What are the rare pathogens that do not grow in routinely used blood culture systems?

Output: uncommon or rare pathogens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the rare pathogens that do not grow in routinely used blood culture systems?. ### Response: uncommon or rare pathogens.


Instruction: What organisms have garnered the most attention?

Output: Bartonella species, Chlamydia species, C burnetii, Brucella species, Legionella species, Tropheryma whipplei, Candida, and non-Candida fungi (particularly Aspergillus species).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What organisms have garnered the most attention?. ### Response: Bartonella species, Chlamydia species, C burnetii, Brucella species, Legionella species, Tropheryma whipplei, Candida, and non-Candida fungi (particularly Aspergillus species)..


Instruction: The last two groups of organisms are especially relevant to what?

Output: PV recipients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The last two groups of organisms are especially relevant to what?. ### Response: PV recipients.


Instruction: What are the last 2 groups of organisms relevant to PV recipients?

Output: staphylococci, enterococci, and aerobic Gram-negative bacilli

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the last 2 groups of organisms relevant to PV recipients?. ### Response: staphylococci, enterococci, and aerobic Gram-negative bacilli.


Instruction: What have been identified in the majority of cases of cul-ture-negative IE caused by fastidious organisms?

Output: Bartonella species, C burnetii, and Brucella species

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have been identified in the majority of cases of cul-ture-negative IE caused by fastidious organisms?. ### Response: Bartonella species, C burnetii, and Brucella species.


Instruction: Which panel shows sinus rhythm?

Output: upper

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which panel shows sinus rhythm?. ### Response: upper.


Instruction: What is the lower panel showing tachycardia onset with the characteristic finding of dissociation of the QRS and P waves?

Output: narrow arrows on P waves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the lower panel showing tachycardia onset with the characteristic finding of dissociation of the QRS and P waves?. ### Response: narrow arrows on P waves.


Instruction: The large arrow signifies continuous recording.

Output: VI, II, and V5 in a patient with junctional tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The large arrow signifies continuous recording.. ### Response: VI, II, and V5 in a patient with junctional tachycardia.


Instruction: What signi-fies continuous recording?

Output: large arrow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What signi-fies continuous recording?. ### Response: large arrow.


Instruction: Who gave permission to reproduce Figure 21. Ongoing management of junctional tachycardia.

Output: Blomström-Lundqvist et al.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who gave permission to reproduce Figure 21. Ongoing management of junctional tachycardia.. ### Response: Blomström-Lundqvist et al..


Instruction: What indicates structural heart disease?

Output: SHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates structural heart disease?. ### Response: SHD.


Instruction: What type of graft patency has been reported to be diminished in patients with diabetes mellitus and the metabolic syndrome?

Output: Vein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of graft patency has been reported to be diminished in patients with diabetes mellitus and the metabolic syndrome?. ### Response: Vein.


Instruction: What is a more rapid progression of native vessel atherosclerosis?

Output: decreased early graft patency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a more rapid progression of native vessel atherosclerosis?. ### Response: decreased early graft patency.


Instruction: What is the association between type 2 diabetes mellitus and impaired endothelial function and intimal degeneration of saphenous vein grafts?

Output: changes that inversely correlate with the metabolic control of the diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between type 2 diabetes mellitus and impaired endothelial function and intimal degeneration of saphenous vein grafts?. ### Response: changes that inversely correlate with the metabolic control of the diabetes mellitus.


Instruction: What has less effect on the properties of the internal mammary artery?

Output: diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has less effect on the properties of the internal mammary artery?. ### Response: diabetes mellitus.


Instruction: What was associated with late vein graft failure?

Output: insulin-dependent diabetes mel-litus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with late vein graft failure?. ### Response: insulin-dependent diabetes mel-litus.


Instruction: How many CABG patients were evaluated?

Output: 501

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many CABG patients were evaluated?. ### Response: 501.


Instruction: How many CABG patients were enrolled in the V A Cooperative Study?

Output: 1074

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many CABG patients were enrolled in the V A Cooperative Study?. ### Response: 1074.


Instruction: How long did the follow-up follow up follow?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the follow-up follow up follow?. ### Response: 10-year.


Instruction: What did Goldman et al282 not find to be an independent predictor of?

Output: diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Goldman et al282 not find to be an independent predictor of?. ### Response: diabetes mellitus.


Instruction: What is diabetes mellitus an independent predictor of?

Output: vein graft patency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is diabetes mellitus an independent predictor of?. ### Response: vein graft patency.


Instruction: What did Sabik et al report as a strong risk factor for after CABG?

Output: diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Sabik et al report as a strong risk factor for after CABG?. ### Response: diabetes mellitus.


Instruction: What is a cor -onary reintervention?

Output: either percutaneous coronary interven-tion or redo CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cor -onary reintervention?. ### Response: either percutaneous coronary interven-tion or redo CABG.


Instruction: What is another term for percutaneous coronary interven-tion?

Output: redo CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for percutaneous coronary interven-tion?. ### Response: redo CABG.


Instruction: Patients treated with insulin or oral medications had a similar elevated risk of undergoing what?

Output: reintervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients treated with insulin or oral medications had a similar elevated risk of undergoing what?. ### Response: reintervention.


Instruction: What is the risk of reintervention lower than in those treated pharmacologically?

Output: P=0.005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of reintervention lower than in those treated pharmacologically?. ### Response: P=0.005.


Instruction: What does the degree of glucose control independently predict?

Output: vein graft patency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the degree of glucose control independently predict?. ### Response: vein graft patency.


Instruction: What may complicate control from the progression of cardio-vascular disease in general?

Output: challenges and inaccuracy of graft patency assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may complicate control from the progression of cardio-vascular disease in general?. ### Response: challenges and inaccuracy of graft patency assessment.


Instruction: What may be complicated by the challenges and inaccuracy of graft patency assessment?

Output: cardio-vascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be complicated by the challenges and inaccuracy of graft patency assessment?. ### Response: cardio-vascular disease.


Instruction: Patients having undergone surgical revascularization are at increased risk for what?

Output: further progression of CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients having undergone surgical revascularization are at increased risk for what?. ### Response: further progression of CAD.


Instruction: Who is at increased risk for further progression of CAD?

Output: Patients having undergone surgical revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is at increased risk for further progression of CAD?. ### Response: Patients having undergone surgical revascularization.


Instruction: Why is there no reason to surmise that CABG patients have any inherent protection from the effects of poorly controlled diabetes mellitus?

Output: Because there is no reason to surmise that CABG patients have any inher -ent protection from the effects of poorly controlled diabetes mellitus and because well-controlled blood sugar markedly improves survival in patients with cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there no reason to surmise that CABG patients have any inherent protection from the effects of poorly controlled diabetes mellitus?. ### Response: Because there is no reason to surmise that CABG patients have any inher -ent protection from the effects of poorly controlled diabetes mellitus and because well-controlled blood sugar markedly improves survival in patients with cardiovascular disease.


Instruction: Well-controlled blood sugar significantly improves what in patients with cardiovascular disease?

Output: survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Well-controlled blood sugar significantly improves what in patients with cardiovascular disease?. ### Response: survival.


Instruction: What is the most prevalent cause of morbidity and mortality in the dia-betic population?

Output: cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most prevalent cause of morbidity and mortality in the dia-betic population?. ### Response: cardiovascular disease.


Instruction: What does sugar significantly improve in patients with cardiovascular disease?

Output: survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does sugar significantly improve in patients with cardiovascular disease?. ### Response: survival.


Instruction: How should long-term glucose control be optimized for all CABG patients?

Output: ideally

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should long-term glucose control be optimized for all CABG patients?. ### Response: ideally.


Instruction: In terms of glucose management, what do CABG patients with dia-beta have to do?

Output: late vein graft failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In terms of glucose management, what do CABG patients with dia-beta have to do?. ### Response: late vein graft failure.


Instruction: What are the consequences of repeat brain imaging and follow-up vascular im-aging in stroke patients?

Output: Diagnostic and thera-peutic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the consequences of repeat brain imaging and follow-up vascular im-aging in stroke patients?. ### Response: Diagnostic and thera-peutic.


Instruction: What is Schneider LB, Libman RB, Kanner R. Utility of brain imaging in stroke?

Output: Patent foramen ovale closure or antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Schneider LB, Libman RB, Kanner R. Utility of brain imaging in stroke?. ### Response: Patent foramen ovale closure or antiplatelet therapy.


Instruction: Who is Sndergaard?

Output: L

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Sndergaard?. ### Response: L.


Instruction: What is imaging in stroke?

Output: repeat brain imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is imaging in stroke?. ### Response: repeat brain imaging.


Instruction: What is AJNR Am J Neuroradiol. 1996;17:1259–1263. Attending the Gore REDUCE Clinical Study Investigators?

Output: Utility of repeat brain imaging in stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AJNR Am J Neuroradiol. 1996;17:1259–1263. Attending the Gore REDUCE Clinical Study Investigators?. ### Response: Utility of repeat brain imaging in stroke.


Instruction: What does antiplatelet therapy do for cryptogenic stroke?

Output: Patent foramen ovale closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does antiplatelet therapy do for cryptogenic stroke?. ### Response: Patent foramen ovale closure.


Instruction: What is the name of the 2017 N Engl J Med 377:1033-1042?

Output: N Engl J Med.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2017 N Engl J Med 377:1033-1042?. ### Response: N Engl J Med..


Instruction: What was gemfibrozil compared to placebo?

Output: 14%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was gemfibrozil compared to placebo?. ### Response: 14%,.


Instruction: What was not incorporated into the routine care of CABG patients?

Output: gemfibrozil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not incorporated into the routine care of CABG patients?. ### Response: gemfibrozil.


Instruction: What is the high risk of side effects associated with gemfibrozil?

Output: myopa-thy and rhabdomyolysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the high risk of side effects associated with gemfibrozil?. ### Response: myopa-thy and rhabdomyolysis.


Instruction: Lower HDL levels are associated with worse long-term sur-vival and higher risk of cardiovascular events after CABG?

Output: 163,164

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Lower HDL levels are associated with worse long-term sur-vival and higher risk of cardiovascular events after CABG?. ### Response: 163,164.


Instruction: What is strong evidence supporting the use of statins after CABG?

Output: Although there is strong evidence supporting the use of statins after CABG, adding gemfibrozil to a patient’s medication regimen can increase the risk of side effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is strong evidence supporting the use of statins after CABG?. ### Response: Although there is strong evidence supporting the use of statins after CABG, adding gemfibrozil to a patient’s medication regimen can increase the risk of side effects.


Instruction: What can add gemfibrozil to a patient's medication regimen increase the risk of?

Output: side effects such as myopa-thy and rhabdomyolysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can add gemfibrozil to a patient's medication regimen increase the risk of?. ### Response: side effects such as myopa-thy and rhabdomyolysis.


Instruction: HDL modulation may help slow the process of what?

Output: saphenous vein graft disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HDL modulation may help slow the process of what?. ### Response: saphenous vein graft disease.


Instruction: What must be tempered by the absence of data on the administration of fenofibrate or niacin therapy after CABG?

Output: HDL modulation may help slow the process of saphenous vein graft disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be tempered by the absence of data on the administration of fenofibrate or niacin therapy after CABG?. ### Response: HDL modulation may help slow the process of saphenous vein graft disease.


Instruction: The administration of these agents on top of statins has proven futile in recent clinical trials?

Output: non-CABG population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The administration of these agents on top of statins has proven futile in recent clinical trials?. ### Response: non-CABG population.


Instruction: What is fenofibrate?

Output: second-line agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is fenofibrate?. ### Response: second-line agents.


Instruction: What is the primary therapeutic target for hyperlipidemia?

Output: LDL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary therapeutic target for hyperlipidemia?. ### Response: LDL.


Instruction: High triglyceride levels are also associated with an elevated risk of developing what?

Output: CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: High triglyceride levels are also associated with an elevated risk of developing what?. ### Response: CAD.


Instruction: Elevated tri-glycerid levels are a marker of what substance?

Output: atherogenic remnant lipopro-teins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Elevated tri-glycerid levels are a marker of what substance?. ### Response: atherogenic remnant lipopro-teins.


Instruction: What are more easily oxidized lipopro-teins?

Output: atherogenic remnant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are more easily oxidized lipopro-teins?. ### Response: atherogenic remnant.


Instruction: What does Triglyceride levels >150 mg/dL tend to be associated with?

Output: a greater burden of small and dense LDL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Triglyceride levels >150 mg/dL tend to be associated with?. ### Response: a greater burden of small and dense LDL.


Instruction: What makes the calculation of the LDL level with the Friedewald formula inaccurate?

Output: Triglyceride levels >150 mg/dL tend to be associated with a greater burden of small and dense LDL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What makes the calculation of the LDL level with the Friedewald formula inaccurate?. ### Response: Triglyceride levels >150 mg/dL tend to be associated with a greater burden of small and dense LDL.


Instruction: How is the non-HDL cholesterol level defined?

Output: the difference between total cholesterol and HDL levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the non-HDL cholesterol level defined?. ### Response: the difference between total cholesterol and HDL levels.


Instruction: What has been suggested as a more accurate tool for risk and treatment assessment in the presence of high triglyceride levels?

Output: Statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been suggested as a more accurate tool for risk and treatment assessment in the presence of high triglyceride levels?. ### Response: Statins.


Instruction: What includes all cholesterol present in lipoprotein particles con-sidered to be atherogenic?

Output: Non-HDL cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What includes all cholesterol present in lipoprotein particles con-sidered to be atherogenic?. ### Response: Non-HDL cholesterol.


Instruction: What are some of the first-line thera-pies in patients with hypertriglyceridemia?

Output: diet modification, exercise, and weight loss

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the first-line thera-pies in patients with hypertriglyceridemia?. ### Response: diet modification, exercise, and weight loss.


Instruction: What is a benefit of statins in lowering non-HDL?

Output: patients with high triglycer -ide levels >200 mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a benefit of statins in lowering non-HDL?. ### Response: patients with high triglycer -ide levels >200 mg/dL.


Instruction: What may be of benefit in lowering non-HDL cholesterol levels in patients with high triglycer -ide levels >200 mg/dL?

Output: Statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be of benefit in lowering non-HDL cholesterol levels in patients with high triglycer -ide levels >200 mg/dL?. ### Response: Statins.


Instruction: What did 2 placebo-controlled trials report that gemfibrozil treatment caused?

Output: marked reductions in triglyceride levels and increased HDL levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did 2 placebo-controlled trials report that gemfibrozil treatment caused?. ### Response: marked reductions in triglyceride levels and increased HDL levels.


Instruction: How many car-diovascular events are there?

Output: 156,174

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many car-diovascular events are there?. ### Response: 156,174.


Instruction: What is the result of increased triglyceride levels?

Output: elevated risk of developing CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the result of increased triglyceride levels?. ### Response: elevated risk of developing CAD.


Instruction: What is a PIVOTAL ISSUES IN HF5.1?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a PIVOTAL ISSUES IN HF5.1?. ### Response: 10.


Instruction: What are some established therapies for chronic HFrEF?

Output: ARNIs,angiotensin-converting enzyme inhibitors (ACEIs),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some established therapies for chronic HFrEF?. ### Response: ARNIs,angiotensin-converting enzyme inhibitors (ACEIs),.


Instruction: What is the name of the isosorbidedinitrate/hydralazine combination?

Output: HYD/ISDN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the isosorbidedinitrate/hydralazine combination?. ### Response: HYD/ISDN.


Instruction: What is ivabradine a selective ifchannelblocker for?

Output: sinoatrial node pacemakercurrent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ivabradine a selective ifchannelblocker for?. ### Response: sinoatrial node pacemakercurrent.


Instruction: In what type of trials have all of these therapies been shown to improve symptoms?

Output: randomized controlled

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what type of trials have all of these therapies been shown to improve symptoms?. ### Response: randomized controlled.


Instruction: What lacks new data as a treatment forHFrEF?

Output: digoxin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What lacks new data as a treatment forHFrEF?. ### Response: digoxin.


Instruction: What focuses on its role as rate control agent foratrial fibrillation (AF) in those with low blood pressure?

Output: digoxin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What focuses on its role as rate control agent foratrial fibrillation (AF) in those with low blood pressure?. ### Response: digoxin.


Instruction: When was the 2017 ECDP focused on optimizing therapy?

Output: FEBRUARY 16, 2021:772 –810 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2017 ECDP focused on optimizing therapy?. ### Response: FEBRUARY 16, 2021:772 –810 2021.


Instruction: More data support an expanded role for what in patients with HFrEF?

Output: ARNIs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: More data support an expanded role for what in patients with HFrEF?. ### Response: ARNIs.


Instruction: ARNIs use as what in some patients naive to ACEIs or ARBtherapies?

Output: denovo therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ARNIs use as what in some patients naive to ACEIs or ARBtherapies?. ### Response: denovo therapy.


Instruction: Evidence for rapid improvement inpatient-reported outcome measures (e.g. symptoms,physical functioning, and quality of life)?

Output: FrEF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence for rapid improvement inpatient-reported outcome measures (e.g. symptoms,physical functioning, and quality of life)?. ### Response: FrEF.


Instruction: What are inpatient-reported outcome measures?

Output: symptoms,physical functioning, and quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are inpatient-reported outcome measures?. ### Response: symptoms,physical functioning, and quality of life.


Instruction: What are the symptoms, physical functioning, and quality of life?

Output: outcome measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the symptoms, physical functioning, and quality of life?. ### Response: outcome measures.


Instruction: How many Pivotal Issues About Heart Failure With Reduced Ejection Fraction?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Pivotal Issues About Heart Failure With Reduced Ejection Fraction?. ### Response: 10.


Instruction: What is of value if rection of MR is delayed beyond the onset of triggers?

Output: referral to a Comprehensive Valve Center for early repair or careful surveillance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is of value if rection of MR is delayed beyond the onset of triggers?. ### Response: referral to a Comprehensive Valve Center for early repair or careful surveillance.


Instruction: What should be con-firmed by repeat sequential TTE?

Output: management decisions that rest on these measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be con-firmed by repeat sequential TTE?. ### Response: management decisions that rest on these measurements.


Instruction: In patients with milder chronic pain, what should be done?

Output: TTE is indicated periodically to evaluate for changes in MR severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with milder chronic pain, what should be done?. ### Response: TTE is indicated periodically to evaluate for changes in MR severity.


Instruction: How is MR confirmed by repeat sequential TTE?

Output: echocardiographic measure-ments are variable, management decisions that rest on these measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is MR confirmed by repeat sequential TTE?. ### Response: echocardiographic measure-ments are variable, management decisions that rest on these measurements.


Instruction: In patients with milder chronic primary MR (Stages A and B), TTE is indicated periodically to evaluate for changes in what?

Output: MR severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with milder chronic primary MR (Stages A and B), TTE is indicated periodically to evaluate for changes in what?. ### Response: MR severity.


Instruction: What is a crucial demarcation point in the natural history of MR?

Output: Symptom onset

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a crucial demarcation point in the natural history of MR?. ### Response: Symptom onset.


Instruction: What is also a trigger for intervention?

Output: Symptom onset

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is also a trigger for intervention?. ### Response: Symptom onset.


Instruction: What may patients fail to recognize or ignore because symptoms develop gradually?

Output: symp-toms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients fail to recognize or ignore because symptoms develop gradually?. ### Response: symp-toms.


Instruction: Natriuretic peptide levels provide objective evidence in patients with what?

Output: chronic severe MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Natriuretic peptide levels provide objective evidence in patients with what?. ### Response: chronic severe MR.


Instruction: What is used as a key determi-nant of LV function in timing MR intervention?

Output: LVEF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used as a key determi-nant of LV function in timing MR intervention?. ### Response: LVEF.


Instruction: What does LVEF often overestimate in MR?

Output: LV function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LVEF often overestimate in MR?. ### Response: LV function.


Instruction: What does global longi-tudinal strain appear more sensitive to in patients with chronic MR?

Output: LV dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does global longi-tudinal strain appear more sensitive to in patients with chronic MR?. ### Response: LV dysfunction.


Instruction: What might give warning that LV function is declining before LVEF becomes abnormal?

Output: Global longi-tudinal strain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might give warning that LV function is declining before LVEF becomes abnormal?. ### Response: Global longi-tudinal strain.


Instruction: What is a novel marker of LV systolic function?

Output: global longitudi-nal strain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a novel marker of LV systolic function?. ### Response: global longitudi-nal strain.


Instruction: What may be useful adjuncts in assessing LV function in patients with chronic MR?

Output: global longitudi-nal strain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be useful adjuncts in assessing LV function in patients with chronic MR?. ### Response: global longitudi-nal strain.


Instruction: What tests are inconclusive or discordant with regard to 1) severity of MR, 2) LV function, or 3) the need for surgery?

Output: noninvasive tests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tests are inconclusive or discordant with regard to 1) severity of MR, 2) LV function, or 3) the need for surgery?. ### Response: noninvasive tests.


Instruction: Noninvasive imaging is adequate for evaluation of what?

Output: MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Noninvasive imaging is adequate for evaluation of what?. ### Response: MR.


Instruction: What may be necessary in some cases when there is a clinical discrepancy?

Output: invasive hemodynamic evalu-ation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be necessary in some cases when there is a clinical discrepancy?. ### Response: invasive hemodynamic evalu-ation.


Instruction: What support a cardiac cause of dyspnea?

Output: Elevated filling pressures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What support a cardiac cause of dyspnea?. ### Response: Elevated filling pressures.


Instruction: What may indicate severely abnormal pathophysiology even when the patient claims to be asymptomatic?

Output: Elevated filling pressures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may indicate severely abnormal pathophysiology even when the patient claims to be asymptomatic?. ### Response: Elevated filling pressures.


Instruction: What is a normal invasive hemodynamic examination in a symptomatic?

Output: symp-toms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a normal invasive hemodynamic examination in a symptomatic?. ### Response: symp-toms.


Instruction: When was this document downloaded?

Output: April 27, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this document downloaded?. ### Response: April 27, 2023.


Instruction: What is the name of the randomised controlled trial of mechanical thrombectomy after intravenous alteplase?

Output: THRACE Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial of mechanical thrombectomy after intravenous alteplase?. ### Response: THRACE Investigators.


Instruction: What was the outcome of the trial?

Output: Mechanical thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the trial?. ### Response: Mechanical thrombectomy.


Instruction: What is the name of the investigators who conducted a randomized trial of intraarterial treatment for acute ischemic stroke?

Output: MR CLEAN Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the investigators who conducted a randomized trial of intraarterial treatment for acute ischemic stroke?. ### Response: MR CLEAN Investigators.


Instruction: How many people were involved in the randomized study?

Output: 111

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were involved in the randomized study?. ### Response: 111.


Instruction: What type of radiography is used in the study of acute ischemia?

Output: emergent chest radiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of radiography is used in the study of acute ischemia?. ### Response: emergent chest radiography.


Instruction: What is the role of emergent chest radiography in evaluation of hyperacute stroke?

Output: Role

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of emergent chest radiography in evaluation of hyperacute stroke?. ### Response: Role.


Instruction: Neurology. 2016;87:782–785.

Output: Neurology. 2016;87:782–785. doi: 10.1212/WNL.0000000000002964 112

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Neurology. 2016;87:782–785.. ### Response: Neurology. 2016;87:782–785. doi: 10.1212/WNL.0000000000002964 112.


Instruction: Who is the Stroke Oxygen Study Collaborative Group?

Output: Stroke Oxygen Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Stroke Oxygen Study Collaborative Group?. ### Response: Stroke Oxygen Study Investigators.


Instruction: What is the name of the group that studies the effects of low-dose oxygen supplementation on death and disability in adults with acute stroke?

Output: Stroke Oxygen Study Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies the effects of low-dose oxygen supplementation on death and disability in adults with acute stroke?. ### Response: Stroke Oxygen Study Collaborative Group.


Instruction: When was the Stroke Oxygen released?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Stroke Oxygen released?. ### Response: April 28, 2023.


Instruction: What is often used as part of a model to diagnose heart failure?

Output: NT -proBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often used as part of a model to diagnose heart failure?. ### Response: NT -proBNP.


Instruction: What was the committee aware of?

Output: the level of NT -proBNP is often used as part  of the criteria for diagnosing heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the committee aware of?. ### Response: the level of NT -proBNP is often used as part  of the criteria for diagnosing heart failure.


Instruction: What is often used as part of the criteria for diagnosing heart failure?

Output: the level of NT -proBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often used as part of the criteria for diagnosing heart failure?. ### Response: the level of NT -proBNP.


Instruction: What was not considered suitable for our purposes in truly identifying the diagnostic accuracy of the test?

Output: NICE 2010 guideline diagnostic pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not considered suitable for our purposes in truly identifying the diagnostic accuracy of the test?. ### Response: NICE 2010 guideline diagnostic pathway.


Instruction: What did the committee conclude from the results of the model?

Output: this population was not directly accounted for

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee conclude from the results of the model?. ### Response: this population was not directly accounted for.


Instruction: What population was not directly accounted for?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What population was not directly accounted for?. ### Response: heart failure.


Instruction: The committee assumed that the model assumed what?

Output: there was no effect on this population of a differential diagnosis if they enter the diagnostic pathway for heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee assumed that the model assumed what?. ### Response: there was no effect on this population of a differential diagnosis if they enter the diagnostic pathway for heart failure.


Instruction: What did the model assume was not directly accounted for?

Output: heart failure population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the model assume was not directly accounted for?. ### Response: heart failure population.


Instruction: What does the definition of MI now include many scenarios?

Output: differ from what was originally meant in the  2010 guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the definition of MI now include many scenarios?. ### Response: differ from what was originally meant in the  2010 guideline.


Instruction: What has changed over time?

Output: the definition of MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has changed over time?. ### Response: the definition of MI.


Instruction: What should no longer be a criterion for early echocardiography?

Output: having a history of myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should no longer be a criterion for early echocardiography?. ### Response: having a history of myocardial infarction.


Instruction: What was no longer considered an appropriate strategy to asses s?

Output: NICE 2010 guideline diagnostic pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was no longer considered an appropriate strategy to asses s?. ### Response: NICE 2010 guideline diagnostic pathway.


Instruction: Why was an original cost-effectiveness analysis conducted for this question?

Output: high clinical and economic importance of this question

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was an original cost-effectiveness analysis conducted for this question?. ### Response: high clinical and economic importance of this question.


Instruction: What did the model seek to determine?

Output: which NT -proBNP threshold is the most cost effective for diagnosing heart  failure in patients presenting with signs and symptoms of heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the model seek to determine?. ### Response: which NT -proBNP threshold is the most cost effective for diagnosing heart  failure in patients presenting with signs and symptoms of heart failure.


Instruction: What is the most cost effective for diagnosing heart failure in patients presenting with signs and symptoms of heart failure?

Output: NT -proBNP threshold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most cost effective for diagnosing heart failure in patients presenting with signs and symptoms of heart failure?. ### Response: NT -proBNP threshold.


Instruction: What were the three NT -proBNP thresholds included in the model?

Output: 400pg/ml, 280pg/ml and 125pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the three NT -proBNP thresholds included in the model?. ### Response: 400pg/ml, 280pg/ml and 125pg/ml.


Instruction: What did the committee not consider it appropriate to use the pooled results of these thresholds for the base -case analysis?

Output: inconsistency in the pooled results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee not consider it appropriate to use the pooled results of these thresholds for the base -case analysis?. ### Response: inconsistency in the pooled results.


Instruction: How many diagnostic accuracy studies did the committee choose for the base case anal ysis?

Output: one

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many diagnostic accuracy studies did the committee choose for the base case anal ysis?. ### Response: one.


Instruction: What was the committee's decision to use the other two diagnostic studies for?

Output: scenario analyses adjusting the population characteristics as appropriate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the committee's decision to use the other two diagnostic studies for?. ### Response: scenario analyses adjusting the population characteristics as appropriate.


Instruction: What did the committee use for the base case analysis?

Output: diagnostic accuracy data from the REFER study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee use for the base case analysis?. ### Response: diagnostic accuracy data from the REFER study.


Instruction: The diagnostic accuracy data from the REFER study was used for what?

Output: base case analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The diagnostic accuracy data from the REFER study was used for what?. ### Response: base case analysis.


Instruction: What was not included in part of the criteria?

Output: NT -proBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not included in part of the criteria?. ### Response: NT -proBNP.


Instruction: What is incorporated into the model to mitigate the effects of incorporation bias?

Output: cost and QALY impact of misdiagnosis for a non -heart failure population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is incorporated into the model to mitigate the effects of incorporation bias?. ### Response: cost and QALY impact of misdiagnosis for a non -heart failure population.


Instruction: What is the cost and QALY impact of misdiagnosis?

Output: assumptions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost and QALY impact of misdiagnosis?. ### Response: assumptions.


Instruction: What is the most cost effective strategy?

Output: NT -proBNP threshold of 400pg/ ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most cost effective strategy?. ### Response: NT -proBNP threshold of 400pg/ ml.


Instruction: How much does the NT -proBNP threshold cost per QALY gained?

Output: £20,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does the NT -proBNP threshold cost per QALY gained?. ### Response: £20,000.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: When was the 2021 Circulation. 143:e72–e227?

Output: February 2, 2021 Circulation. 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2021 Circulation. 143:e72–e227?. ### Response: February 2, 2021 Circulation. 2021.


Instruction: What is the DOI: 10.1161/CIR.0000000000000923 e214?

Output: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI: 10.1161/CIR.0000000000000923 e214?. ### Response: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease.


Instruction: What remains essential in endocarditis?

Output: The early echo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains essential in endocarditis?. ### Response: The early echo.


Instruction: What criteria did Lamas CC, Eykyn SJ suggest modifications to?

Output: Duke criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria did Lamas CC, Eykyn SJ suggest modifications to?. ### Response: Duke criteria.


Instruction: How many pathologically proven cases were analysed?

Output: 118

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pathologically proven cases were analysed?. ### Response: 118.


Instruction: Infective endocarditis: comparison with transesophageal echocar-diography and intraoperative findings?

Output: Multislice computed tomog-raphy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis: comparison with transesophageal echocar-diography and intraoperative findings?. ### Response: Multislice computed tomog-raphy.


Instruction: Dis. 1997;25:713–9. Curry C, Körfer R, Horstkotte D. What is the name of the disease that causes prosthetic valves to end?

Output: left-sided endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dis. 1997;25:713–9. Curry C, Körfer R, Horstkotte D. What is the name of the disease that causes prosthetic valves to end?. ### Response: left-sided endocarditis.


Instruction: Heart. 2001;85:590–3.

Output: 61

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Heart. 2001;85:590–3.. ### Response: 61.


Instruction: Feuchtner GM, Stolzmann P, Dichtl W, et al. Comparing multislice computed tomog-raphy in infection?

Output: 61. Feuchtner GM, Stolzmann P , Dichtl W, et al. Multislice computed tomog-raphy in infective endocarditis: comparison with transesophageal echocar -diography and intraoperative findings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Feuchtner GM, Stolzmann P, Dichtl W, et al. Comparing multislice computed tomog-raphy in infection?. ### Response: 61. Feuchtner GM, Stolzmann P , Dichtl W, et al. Multislice computed tomog-raphy in infective endocarditis: comparison with transesophageal echocar -diography and intraoperative findings.


Instruction: What was the name of the 2009 issue of Coll Cardiol?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the 2009 issue of Coll Cardiol?. ### Response: J Am Coll Cardiol.


Instruction: What did Gahide G, Bommart S, Demaria R, et al. find in aortic endocarditis: findings on cardiac CT?

Output: Preoperative evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Gahide G, Bommart S, Demaria R, et al. find in aortic endocarditis: findings on cardiac CT?. ### Response: Preoperative evaluation.


Instruction: When was the AJR Am J Roentgenol published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the AJR Am J Roentgenol published?. ### Response: 2010.


Instruction: What should multi-detector CT scan be used for?

Output: Aortic valve infective endocardi-tis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should multi-detector CT scan be used for?. ### Response: Aortic valve infective endocardi-tis.


Instruction: What is the name of the study that was published by the Agency for Healthcare Research and Quality?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that was published by the Agency for Healthcare Research and Quality?. ### Response: 2011.


Instruction: What year was Quality published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Quality published?. ### Response: 2011.


Instruction: What is a complementary method to echocar -diography?

Output: oroscopic assessment of me-chanical disc prostheses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a complementary method to echocar -diography?. ### Response: oroscopic assessment of me-chanical disc prostheses.


Instruction: What is the value of prostheses?

Output: its value as a complementary method to echocar -diography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of prostheses?. ### Response: its value as a complementary method to echocar -diography.


Instruction: When did Vogel W, Nishimi M, Kawano H, et al. Obstruction of St Jude Medical valves in the aortic position: significance of a combination of cineradiog-raphy and echocardiography.

Output: 67

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Vogel W, Nishimi M, Kawano H, et al. Obstruction of St Jude Medical valves in the aortic position: significance of a combination of cineradiog-raphy and echocardiography.. ### Response: 67.


Instruction: What is Cineradiography used for?

Output: determination of normal and abnormal function in mechanical heart valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Cineradiography used for?. ### Response: determination of normal and abnormal function in mechanical heart valves.


Instruction: What is a meta-analysis of 18F-FDG PET/CT in the diagnosis of?

Output: infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of 18F-FDG PET/CT in the diagnosis of?. ### Response: infective endocarditis.


Instruction: What is the role of 18F-FDG PET/CT in the diagnosis of infective endocarditis?

Output: Meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of 18F-FDG PET/CT in the diagnosis of infective endocarditis?. ### Response: Meta-analysis.


Instruction: What are the two options for the diagnosis?

Output: native valve and prosthetic valve endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two options for the diagnosis?. ### Response: native valve and prosthetic valve endocarditis.


Instruction: Which side of the heart is native versus prosthetic?

Output: left-sided

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which side of the heart is native versus prosthetic?. ### Response: left-sided.


Instruction: What is the difference between native and prosthetic valves endocarditis?

Output: 18F-fluorodeoxyglucose positron emission tomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between native and prosthetic valves endocarditis?. ### Response: 18F-fluorodeoxyglucose positron emission tomography.


Instruction: What are the differences between native vs prosthetic valvoces?

Output: Suggested modifications to the Duke criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between native vs prosthetic valvoces?. ### Response: Suggested modifications to the Duke criteria.


Instruction: How does dual-time-point FDG PET/CT imaging compare to prosthetic heart valves?

Output: 71

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does dual-time-point FDG PET/CT imaging compare to prosthetic heart valves?. ### Response: 71.


Instruction: When did Fowler VG Jr, Li J, Corey GR, et al. use echocardiography?

Output: 72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Fowler VG Jr, Li J, Corey GR, et al. use echocardiography?. ### Response: 72.


Instruction: What is the role of echocardiography in evaluation of patients with Staphylococcus aureus bacteremia?

Output: experience in 103 pa-

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of echocardiography in evaluation of patients with Staphylococcus aureus bacteremia?. ### Response: experience in 103 pa-.


Instruction: What percentage of deaths were reduced with monotherapy RASi compared to dualRASi therapy?

Output: 9%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of deaths were reduced with monotherapy RASi compared to dualRASi therapy?. ### Response: 9%.


Instruction: How long was the mean follow-up of the patients with dualRASi?

Output: 52 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the mean follow-up of the patients with dualRASi?. ### Response: 52 months.


Instruction: What was the marginal reduction of 20% in serum creatinine by dual therapy versus monotherapy?

Output: doubling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the marginal reduction of 20% in serum creatinine by dual therapy versus monotherapy?. ### Response: doubling.


Instruction: How long did the study last?

Output: 37 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: 37 months.


Instruction: What was the mean follow-up of the study?

Output: 37 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean follow-up of the study?. ### Response: 37 months.


Instruction: The lower con fidence interval reaches what?

Output: thenull

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The lower con fidence interval reaches what?. ### Response: thenull.


Instruction: What does dual therapy reduce albuminuria and BP compared to monotherapy?

Output: moderately

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does dual therapy reduce albuminuria and BP compared to monotherapy?. ### Response: moderately.


Instruction: What causes more hyperkalemia?

Output: dual therapydoes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes more hyperkalemia?. ### Response: dual therapydoes.


Instruction: What causes more hyperkalemia and AKI?

Output: dual therapydoes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes more hyperkalemia and AKI?. ### Response: dual therapydoes.


Instruction: What was the overall quality of the evidence forharm?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall quality of the evidence forharm?. ### Response: moderate.


Instruction: Why was the network meta-analysis moderate?

Output: concerns regarding inconsistency for all-cause mortality and CV events and serious imprecision forESKD due to wide CIs that indicated appreciable bene ﬁtsand harms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the network meta-analysis moderate?. ### Response: concerns regarding inconsistency for all-cause mortality and CV events and serious imprecision forESKD due to wide CIs that indicated appreciable bene ﬁtsand harms.


Instruction: Inconsistency for all-cause mortality and CV events and serious imprecision forESKD due to wide CIs that indicated appreciable bene fitsand what?

Output: harms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inconsistency for all-cause mortality and CV events and serious imprecision forESKD due to wide CIs that indicated appreciable bene fitsand what?. ### Response: harms.


Instruction: The ERT review rated the quality of evidence to be what for studies that compared dual with mono RASi?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ERT review rated the quality of evidence to be what for studies that compared dual with mono RASi?. ### Response: moderate.


Instruction: What was the quality of the evidence for most outcomes?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence for most outcomes?. ### Response: moderate.


Instruction: What was unclear reporting for for Cochrane risk of bias282domains?

Output: random sequence generation, and allocation concealment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was unclear reporting for for Cochrane risk of bias282domains?. ### Response: random sequence generation, and allocation concealment.


Instruction: What was downgraded because of serious imprecision?

Output: the quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was downgraded because of serious imprecision?. ### Response: the quality of the evidence.


Instruction: How many studies reported all-cause mortality?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies reported all-cause mortality?. ### Response: 1.


Instruction: What was downgraded due to wide con fidence intervals that indicate appreciable bene fitsand harms?

Output: all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was downgraded due to wide con fidence intervals that indicate appreciable bene fitsand harms?. ### Response: all-cause mortality.


Instruction: What was the quality of the evidence downgraded to for serious adverse events?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence downgraded to for serious adverse events?. ### Response: moderate.


Instruction: What does the Work Group believe is more important than preventinghyperkalemia and AKI?

Output: reduction ofalbuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Work Group believe is more important than preventinghyperkalemia and AKI?. ### Response: reduction ofalbuminuria.


Instruction: What is unclear in view of the absence of effects in the reduction ofalbuminuria?

Output: The signi ﬁcance of these bene ﬁcial effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unclear in view of the absence of effects in the reduction ofalbuminuria?. ### Response: The signi ﬁcance of these bene ﬁcial effects.


Instruction: The Work Group believes that this recommendation places a higher importance on what?

Output: preventinghyperkalemia and AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Work Group believes that this recommendation places a higher importance on what?. ### Response: preventinghyperkalemia and AKI.


Instruction: What is unclear in view of the absence of effects in GFR during the follow-up period of the trials?

Output: The signi ﬁcance of these bene ﬁcial effects onalbuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unclear in view of the absence of effects in GFR during the follow-up period of the trials?. ### Response: The signi ﬁcance of these bene ﬁcial effects onalbuminuria.


Instruction: What has been found for dual therapy in HF?

Output: somebeneﬁt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been found for dual therapy in HF?. ### Response: somebeneﬁt.


Instruction: What year did the Euro Heart Survey on acute coronary syndromes take place?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Euro Heart Survey on acute coronary syndromes take place?. ### Response: 2004.


Instruction: What is the name of the survey that was conducted in 2004?

Output: The second Euro Heart Survey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the survey that was conducted in 2004?. ### Response: The second Euro Heart Survey.


Instruction: When was the Eur Heart J.27:2285–93.16?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur Heart J.27:2285–93.16?. ### Response: 2006.


Instruction: What is one of the recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI?

Output: McManus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI?. ### Response: McManus.


Instruction: What is the name of the journal that describes recent trends and out-comes of acute myocardial infarction and percutaneous coronary interven-tion?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that describes recent trends and out-comes of acute myocardial infarction and percutaneous coronary interven-tion?. ### Response: J Am Coll Cardiol.


Instruction: What is the association between adoption of evidence-based treatment and survival for ST-elevation myo-cardial infarction?

Output: Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between adoption of evidence-based treatment and survival for ST-elevation myo-cardial infarction?. ### Response: Association.


Instruction: When did JAMA publish 305:1677–84.19?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA publish 305:1677–84.19?. ### Response: 2011.


Instruction: How long does it take for a patient to recover from an acute myocardial infarction?

Output: 30-day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a patient to recover from an acute myocardial infarction?. ### Response: 30-day.


Instruction: What is the name of the study that examined the patterns of hospital performance in heart failure?

Output: Euro Heart Survey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the patterns of hospital performance in heart failure?. ### Response: Euro Heart Survey.


Instruction: How long did it take to get back to work after a 30-day infarct?

Output: 407–13.20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to get back to work after a 30-day infarct?. ### Response: 407–13.20.


Instruction: When was Circ Cardiovasc Qual Outcomes published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circ Cardiovasc Qual Outcomes published?. ### Response: 2009.


Instruction: What year did Ann In-tern Med publish 156:618–26.21?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann In-tern Med publish 156:618–26.21?. ### Response: 2012.


Instruction: What is one of the reasons for the lack of use of reperfusion therapy in patients with ST-segment el-evation myocardial infarction?

Output: Implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the reasons for the lack of use of reperfusion therapy in patients with ST-segment el-evation myocardial infarction?. ### Response: Implications.


Instruction: What is the baseline risk of major bleed-ing in non-ST-segment-elevation myocardial infarction?

Output: CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress AD-verse outcomes with Early implementation of the ACC/AHA Guidelines) Bleeding Score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the baseline risk of major bleed-ing in non-ST-segment-elevation myocardial infarction?. ### Response: CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress AD-verse outcomes with Early implementation of the ACC/AHA Guidelines) Bleeding Score.


Instruction: What does CRUSADE stand for?

Output: Can Rapid risk stratification of Unstable angina patients Suppress AD-verse outcomes with Early implementation of the ACC/AHA Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CRUSADE stand for?. ### Response: Can Rapid risk stratification of Unstable angina patients Suppress AD-verse outcomes with Early implementation of the ACC/AHA Guidelines.


Instruction: What is a comparison of card iovas cular health between US A rmy and civilians?

Output: Journal of the American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison of card iovas cular health between US A rmy and civilians?. ### Response: Journal of the American Heart Association.


Instruction: When was Spotlight: Hypertension and stroke published?

Output: June 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Spotlight: Hypertension and stroke published?. ### Response: June 2011.


Instruction: What is the name of the website that VA Health Services Research & Development created?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the website that VA Health Services Research & Development created?. ### Response: www.hsrd.research.va.gov.


Instruction: What year was hyperrtension stroke first reported?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was hyperrtension stroke first reported?. ### Response: 2011.


Instruction: What year did the American Heart Association publish a report on heart disease and stroke statistics?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the American Heart Association publish a report on heart disease and stroke statistics?. ### Response: 2019.


Instruction: What is the name of the subgroup that reviews VA guidelines?

Output: Evidence Review Subgroup

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the subgroup that reviews VA guidelines?. ### Response: Evidence Review Subgroup.


Instruction: What is a GRADE guideline?

Output: 15. Going from evidence to recommendation -determinants of a recommendation's direction and strength

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a GRADE guideline?. ### Response: 15. Going from evidence to recommendation -determinants of a recommendation's direction and strength.


Instruction: Who is the director of the VA's Evidence Review Subgroup?

Output: Office of Quality & Performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the director of the VA's Evidence Review Subgroup?. ### Response: Office of Quality & Performance.