Instruction: What is the classi fication of strong and weak inGRADE) raising concerns that clinicians and patients may opt for less-intensivetreatment?

Output: weak (in the dichotomous classi ﬁcation of strong and weak inGRADE), raising concerns that clinicians and patients maydecide to ignore the guidance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the classi fication of strong and weak inGRADE) raising concerns that clinicians and patients may opt for less-intensivetreatment?. ### Response: weak (in the dichotomous classi ﬁcation of strong and weak inGRADE), raising concerns that clinicians and patients maydecide to ignore the guidance.


Instruction: The Work Group debated whether to provide a recommendation for an SBP target of at least 140mm Hg for all patients with what disease?

Output: CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Work Group debated whether to provide a recommendation for an SBP target of at least 140mm Hg for all patients with what disease?. ### Response: CKD.


Instruction: What is the SBP target for all patients with CKD?

Output: <140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the SBP target for all patients with CKD?. ### Response: <140 mm Hg.


Instruction: Why was the more complex alternative rejected?

Output: it would probablypersuade clinicians to continue to adopt an SBP targetof<140 mm Hg for all CKD patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the more complex alternative rejected?. ### Response: it would probablypersuade clinicians to continue to adopt an SBP targetof<140 mm Hg for all CKD patients.


Instruction: What does aweak recommendation mean?

Output: the majority of peoplewould want the recommended course of action, but somewould not

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does aweak recommendation mean?. ### Response: the majority of peoplewould want the recommended course of action, but somewould not.


Instruction: What is a strongrecommendation?

Output: implies that most patients and caregiverswould want the recommended course of action

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strongrecommendation?. ### Response: implies that most patients and caregiverswould want the recommended course of action.


Instruction: What should clinicians understand about weak recommendations?

Output: the nature and rationale of the recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should clinicians understand about weak recommendations?. ### Response: the nature and rationale of the recommendations.


Instruction: Who should engage in shared decision-making with patients?

Output: clinicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should engage in shared decision-making with patients?. ### Response: clinicians.


Instruction: What did the Work Group choose not to provide as a target for?

Output: DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group choose not to provide as a target for?. ### Response: DBP.


Instruction: Why did Work Group choose not to provide a target for DBP alongside the targetedSBP120 mm Hg?

Output: it would probablypersuade clinicians to continue to adopt an SBP targetof<140 mm Hg for all CKD patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did Work Group choose not to provide a target for DBP alongside the targetedSBP120 mm Hg?. ### Response: it would probablypersuade clinicians to continue to adopt an SBP targetof<140 mm Hg for all CKD patients.


Instruction: What is essential for young patients with diastolic hypertension?

Output: target DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is essential for young patients with diastolic hypertension?. ### Response: target DBP.


Instruction: What was an inclusion criterion in earlier trials in the general population?

Output: DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was an inclusion criterion in earlier trials in the general population?. ### Response: DBP.


Instruction: What is common in CKD?

Output: wide pulse pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is common in CKD?. ### Response: wide pulse pressure.


Instruction: Achieving SBP 120mm Hg will almost certainly result in what in the great majority of patients?

Output: DBP <70 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Achieving SBP 120mm Hg will almost certainly result in what in the great majority of patients?. ### Response: DBP <70 mm Hg.


Instruction: In the vast majority of patients, what is the DBP target?

Output: <70 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the vast majority of patients, what is the DBP target?. ### Response: <70 mm Hg.


Instruction: What makes the provision of separate DBP targets redundant?

Output: wide pulse pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What makes the provision of separate DBP targets redundant?. ### Response: wide pulse pressure.


Instruction: What should be considered as part of shared decision making?

Output: Switching

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered as part of shared decision making?. ### Response: Switching.


Instruction: What is the value placed on avoiding gynaecomastia varies from patient to patient?

Output: Switching should be considered as part of shared decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value placed on avoiding gynaecomastia varies from patient to patient?. ### Response: Switching should be considered as part of shared decision making.


Instruction: The clinically important reduction in all-cause mortality supported a recommendation to offer what to all people with HFREF?

Output: MRAs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The clinically important reduction in all-cause mortality supported a recommendation to offer what to all people with HFREF?. ### Response: MRAs.


Instruction: What should be offered to all people with HFREF who remain symptomatic despite treatment with beta-blockers and ACE inhibitors?

Output: MRAs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be offered to all people with HFREF who remain symptomatic despite treatment with beta-blockers and ACE inhibitors?. ### Response: MRAs.


Instruction: What did the committee recommend that clinicians seek?

Output: specialist advice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee recommend that clinicians seek?. ### Response: specialist advice.


Instruction: What should clinicians seek in the case of deterioration?

Output: specialist advice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should clinicians seek in the case of deterioration?. ### Response: specialist advice.


Instruction: What should patients taking MRAs do instead of automatically discontinuing the MRA?

Output: seek specialist advice in the case of deterioration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients taking MRAs do instead of automatically discontinuing the MRA?. ### Response: seek specialist advice in the case of deterioration.


Instruction: What does DASH stand for?

Output: tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does DASH stand for?. ### Response: tension.


Instruction: What is the name of the collaborative research group that studies the effects of dietary patterns on blood pressure?

Output: DASH Collaborative ResearchGroup

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the collaborative research group that studies the effects of dietary patterns on blood pressure?. ### Response: DASH Collaborative ResearchGroup.


Instruction: When was the DASH-Sodium Collaborative Research Group founded?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the DASH-Sodium Collaborative Research Group founded?. ### Response: 2001.


Instruction: What is the acronym for the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?

Output: ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?. ### Response: ALLHAT.


Instruction: Who is the Officer and Coordinator for the ALLHAT Collab-orative Research Group?

Output: ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Officer and Coordinator for the ALLHAT Collab-orative Research Group?. ### Response: ALLHAT.


Instruction: What is the name of the Systolic Hypertension in the ElderlyProgram?

Output: SHEP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Systolic Hypertension in the ElderlyProgram?. ### Response: SHEP.


Instruction: What does SHEP stand for?

Output: Systolic Hypertension in the ElderlyProgram

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SHEP stand for?. ### Response: Systolic Hypertension in the ElderlyProgram.


Instruction: What increase physicians’ counseling about smoking cessation?

Output: Staff involvement and specialfollow-up time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increase physicians’ counseling about smoking cessation?. ### Response: Staff involvement and specialfollow-up time.


Instruction: What is the name of the randomized, controlled trial of a program based on behavioral theory and practice with standardized patients?

Output: Efficacy of resident training insmoking cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, controlled trial of a program based on behavioral theory and practice with standardized patients?. ### Response: Efficacy of resident training insmoking cessation.


Instruction: How many strategies did Rosser and McDowell use to document smoking status?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strategies did Rosser and McDowell use to document smoking status?. ### Response: three.


Instruction: What did Richard RJ and Duncan CL do to train physicians about smoking cessation?

Output: a controlled trial in private practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Richard RJ and Duncan CL do to train physicians about smoking cessation?. ### Response: a controlled trial in private practice.


Instruction: What is a controlled trial in private practice?

Output: Training physicians aboutsmoking cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a controlled trial in private practice?. ### Response: Training physicians aboutsmoking cessation.


Instruction: When was the J Gen InternMed.4:482–9.824.

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Gen InternMed.4:482–9.824.. ### Response: 1989.


Instruction: When were the ACCF/AHA guidelines for coronary artery bypass graft surgery published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were the ACCF/AHA guidelines for coronary artery bypass graft surgery published?. ### Response: 2011.


Instruction: What is the name of the TaskForce on Practice Guidelines?

Output: AmericanCollege of Cardiology Foundation/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the TaskForce on Practice Guidelines?. ### Response: AmericanCollege of Cardiology Foundation/American Heart Association.


Instruction: What is the name of the document published by the American College of Cardiology Foundation Task Force on Clinical Expert ConsensusDocuments?

Output: A Report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document published by the American College of Cardiology Foundation Task Force on Clinical Expert ConsensusDocuments?. ### Response: A Report.


Instruction: When was Circulation. 2011 published?

Output: November 7, 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation. 2011 published?. ### Response: November 7, 2011.


Instruction: What was published online beforeprint on November 7, 2011?

Output: Circulation. 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was published online beforeprint on November 7, 2011?. ### Response: Circulation. 2011.


Instruction: Who published the ACCF/ACG/AHA 2008expert consensus document?

Output: American Collegeof Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the ACCF/ACG/AHA 2008expert consensus document?. ### Response: American Collegeof Cardiology Foundation.


Instruction: What does the Collegeof Cardiology Foundation Task Force on Clinical Expert ConsensusDocuments focus on?

Output: reducing the gastrointestinal risks ofantiplatelet therapy and NSAID use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Collegeof Cardiology Foundation Task Force on Clinical Expert ConsensusDocuments focus on?. ### Response: reducing the gastrointestinal risks ofantiplatelet therapy and NSAID use.


Instruction: When was Circulation published?

Output: November 7, 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation published?. ### Response: November 7, 2011.


Instruction: What is clopidogrel-drug interactions?

Output: A population-based study of thedrug interaction between proton pump inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel-drug interactions?. ### Response: A population-based study of thedrug interaction between proton pump inhibitors.


Instruction: Where did Juurlink DN, Gomes T, Ko DT, et al. study?

Output: population-based study of thedrug interaction between proton pump inhibitors and clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did Juurlink DN, Gomes T, Ko DT, et al. study?. ### Response: population-based study of thedrug interaction between proton pump inhibitors and clopidogrel.


Instruction: What is clopidogrel with or withoutomeprazole used for in coronary artery disease?

Output: converting enzyme inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel with or withoutomeprazole used for in coronary artery disease?. ### Response: converting enzyme inhibitor.


Instruction: When did Holmes DR Jr, Dehmer GJ, Kaul S, et al. publish their findings?

Output: November 7, 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Holmes DR Jr, Dehmer GJ, Kaul S, et al. publish their findings?. ### Response: November 7, 2011.


Instruction: How many days of follow-up did clopidogrel and placebo groups have?

Output: 30

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days of follow-up did clopidogrel and placebo groups have?. ### Response: 30.


Instruction: How many groups were studied in a prospective RCT exam-ining the effect of the timing of the discontinuation before CABG?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many groups were studied in a prospective RCT exam-ining the effect of the timing of the discontinuation before CABG?. ### Response: 3.


Instruction: What group continued to the day of surgery?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group continued to the day of surgery?. ### Response: clopidogrel.


Instruction: How many days before surgery was clopidogrel discontinued?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days before surgery was clopidogrel discontinued?. ### Response: 5.


Instruction: What did patients in the continuation group experience?

Output: increased rates of bleeding and blood product utilization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients in the continuation group experience?. ### Response: increased rates of bleeding and blood product utilization.


Instruction: Patients in the 5-day discontinuation groups had low bleeding rates and what else?

Output: blood product usage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients in the 5-day discontinuation groups had low bleeding rates and what else?. ### Response: blood product usage.


Instruction: What did 5-day discontinuation groups have that resembled historical con-trol values?

Output: blood product usage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did 5-day discontinuation groups have that resembled historical con-trol values?. ### Response: blood product usage.


Instruction: What was not observed in a retrospective analysis of a nonrandomized subgroup of patients in the PLATO trial?

Output: differences in the rates of reop-er

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not observed in a retrospective analysis of a nonrandomized subgroup of patients in the PLATO trial?. ### Response: differences in the rates of reop-er.


Instruction: What was observed between patients allocated ticagrelor and patients who received clopidogrel?

Output: no significant differences in CABG-related bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was observed between patients allocated ticagrelor and patients who received clopidogrel?. ### Response: no significant differences in CABG-related bleeding.


Instruction: What was not observed differences in the rates of reop-eration?

Output: CABG-related bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not observed differences in the rates of reop-eration?. ### Response: CABG-related bleeding.


Instruction: How long did the study last?

Output: 15-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: 15-month.


Instruction: How long was the course of the study?

Output: 15-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the course of the study?. ### Response: 15-month.


Instruction: Prasugrel and clopidogrel had significantly higher rates of what type of bleeding after CABG?

Output: TIMI major or minor bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prasugrel and clopidogrel had significantly higher rates of what type of bleeding after CABG?. ### Response: TIMI major or minor bleeding.


Instruction: What was the OR of prasugrrl compared to clopidospirin?

Output: 6.53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the OR of prasugrrl compared to clopidospirin?. ### Response: 6.53.


Instruction: How much bleeding hazard was observed with praspigrel?

Output: excess

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much bleeding hazard was observed with praspigrel?. ### Response: excess.


Instruction: During the 15-month course of study, what was the rate of TIMI major or minor bleeding?

Output: 21.9%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: During the 15-month course of study, what was the rate of TIMI major or minor bleeding?. ### Response: 21.9%.


Instruction: What should prompt consideration of an alternative antiplatelet strategy in patients with STEMI who may require urgent CABG during their index hospitalization?

Output: The excess bleeding hazard observed with prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should prompt consideration of an alternative antiplatelet strategy in patients with STEMI who may require urgent CABG during their index hospitalization?. ### Response: The excess bleeding hazard observed with prasugrel.


Instruction: What is referenced in Section 4.1 of the 2011 ACCF/AHA Guideline for?

Output: 12 receptor antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is referenced in Section 4.1 of the 2011 ACCF/AHA Guideline for?. ### Response: 12 receptor antagonists.


Instruction: Where is the 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery referenced?

Output: Section 4.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery referenced?. ### Response: Section 4.1.


Instruction: What should be initiated in the first 24 hours in patients with STEMI who do not have beta blockers?

Output: Oral beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be initiated in the first 24 hours in patients with STEMI who do not have beta blockers?. ### Response: Oral beta blockers.


Instruction: What is the first 24 hours in patients with STEMI?

Output: Oral beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first 24 hours in patients with STEMI?. ### Response: Oral beta blockers.


Instruction: What are some contraindications to use oral beta blockers?

Output: signs of HF, evidence of a low output state, increased risk for cardiogenic shock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some contraindications to use oral beta blockers?. ### Response: signs of HF, evidence of a low output state, increased risk for cardiogenic shock.


Instruction: What is a risk factor for cardiogenic shock?

Output: age >70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for cardiogenic shock?. ### Response: age >70 years.


Instruction: What should be continued during and af-ter hospitalization for all patients with STEMI and with no contraindications?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be continued during and af-ter hospitalization for all patients with STEMI and with no contraindications?. ### Response: Beta blockers.


Instruction: What are the risk factors for cardiogenic shock?

Output: greater the number of risk factors present

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risk factors for cardiogenic shock?. ### Response: greater the number of risk factors present.


Instruction: What is the age of the person who is at risk?

Output: >70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age of the person who is at risk?. ### Response: >70 years.


Instruction: How is the systolic BP measured?

Output: <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the systolic BP measured?. ### Response: <120 mm Hg.


Instruction: What is the rate 60 bpm and increased time since onset of symptoms of STEMI?

Output: heart rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rate 60 bpm and increased time since onset of symptoms of STEMI?. ### Response: heart rate.


Instruction: What is the only weight-loss strategy with long-term results?

Output: bariatric surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only weight-loss strategy with long-term results?. ### Response: bariatric surgery.


Instruction: What has shown signifi-cant improvements in cardiometabolic parameters?

Output: Observational studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has shown signifi-cant improvements in cardiometabolic parameters?. ### Response: Observational studies.


Instruction: What has shown improvement in cardiometabolic parameters, quality of life, and cardiac mechanics after bariatric surgery?

Output: Observational studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has shown improvement in cardiometabolic parameters, quality of life, and cardiac mechanics after bariatric surgery?. ### Response: Observational studies.


Instruction: Many patients after CABG with a BMI of 35 kg/m2 would qualify for what?

Output: Bariatric surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Many patients after CABG with a BMI of 35 kg/m2 would qualify for what?. ### Response: Bariatric surgery.


Instruction: What type of surgery has been shown to be safe in stable patients with CAD who have not had a recent MI?

Output: Bariatric surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery has been shown to be safe in stable patients with CAD who have not had a recent MI?. ### Response: Bariatric surgery.


Instruction: What is the cornerstone of the management of metabolic syndrome?

Output: lifestyle modification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cornerstone of the management of metabolic syndrome?. ### Response: lifestyle modification.


Instruction: What can improve all of the metabolic syndrome components?

Output: Lifestyle changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can improve all of the metabolic syndrome components?. ### Response: Lifestyle changes.


Instruction: What can effectively improve hypertriglyceridemia?

Output: Diets low in carbohydrates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can effectively improve hypertriglyceridemia?. ### Response: Diets low in carbohydrates.


Instruction: High protein intake, along with a high consumption of fruits, vegetables, and nonfat dairy products, can improve what?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: High protein intake, along with a high consumption of fruits, vegetables, and nonfat dairy products, can improve what?. ### Response: BP.


Instruction: What is needed for hypertension, diabe-tes mellitus, and dyslipidemia despite lifestyle changes?

Output: pharmacological treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed for hypertension, diabe-tes mellitus, and dyslipidemia despite lifestyle changes?. ### Response: pharmacological treatment.


Instruction: What has been shown to significantly reduce the prevalence of meta-bolic syndrome?

Output: bariatric surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to significantly reduce the prevalence of meta-bolic syndrome?. ### Response: bariatric surgery.


Instruction: The assessment of central distribution of fat is rea-sonable in what?

Output: CABG patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The assessment of central distribution of fat is rea-sonable in what?. ### Response: CABG patients.


Instruction: What is rea-sonable in CABG patients?

Output: The assessment of central distribution of fat

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rea-sonable in CABG patients?. ### Response: The assessment of central distribution of fat.


Instruction: What can be done to assess central distribution of fat?

Output: measuring waist and hip circumference and calculating waist-to-hip ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be done to assess central distribution of fat?. ### Response: measuring waist and hip circumference and calculating waist-to-hip ratio.


Instruction: Who can be considered for bariatric surgery?

Output: CABG patients with a BMI >35 kg/m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who can be considered for bariatric surgery?. ### Response: CABG patients with a BMI >35 kg/m2.


Instruction: What percentage of patients have been identified as having poor preoperative nutritional status?

Output: 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have been identified as having poor preoperative nutritional status?. ### Response: 20%.


Instruction: What is the BMI of CABG patients?

Output: >35 kg/m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BMI of CABG patients?. ### Response: >35 kg/m2.


Instruction: How many patients have been identified as having poor preoperative nutritional sta-tus before undergoing cardiac surgery?

Output: 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients have been identified as having poor preoperative nutritional sta-tus before undergoing cardiac surgery?. ### Response: 20%.


Instruction: Several nutritional screening tools exist, including what?

Output: Malnutrition Universal Screening Tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Several nutritional screening tools exist, including what?. ### Response: Malnutrition Universal Screening Tool.


Instruction: When the Malnutrition Universal Screening Tool score is added to the EuroSCORE in a multivariable model evaluating perioperative risk, what is the prediction of the model?

Output: the prediction of the model for both postoperative complications and mortal-ity is significantly improved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When the Malnutrition Universal Screening Tool score is added to the EuroSCORE in a multivariable model evaluating perioperative risk, what is the prediction of the model?. ### Response: the prediction of the model for both postoperative complications and mortal-ity is significantly improved.


Instruction: Preoperative malnutrition has been shown to predict what?

Output: adverse postopera-tive events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preoperative malnutrition has been shown to predict what?. ### Response: adverse postopera-tive events.


Instruction: What is the prediction of the model for both postoperative complications and mortal-ity significantly improved compared with the use of the EuroSCORE alone?

Output: When the Malnutrition Universal Screening Tool score is added to the EuroSCORE in a multivariable model evaluating perioperative risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prediction of the model for both postoperative complications and mortal-ity significantly improved compared with the use of the EuroSCORE alone?. ### Response: When the Malnutrition Universal Screening Tool score is added to the EuroSCORE in a multivariable model evaluating perioperative risk.


Instruction: What has been shown to predict adverse postoperative events?

Output: Preoperative malnutrition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to predict adverse postoperative events?. ### Response: Preoperative malnutrition.


Instruction: How long does vasopressor treatment last?

Output: >11 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does vasopressor treatment last?. ### Response: >11 days.


Instruction: What does antibiotic treatment last for?

Output: >21 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does antibiotic treatment last for?. ### Response: >21 days.


Instruction: Who is the Chair of Harvard Medical School?

Output: Patrick T. O’Gara

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chair of Harvard Medical School?. ### Response: Patrick T. O’Gara.


Instruction: What is the name of the Vice Chair of Tulane University School of Medicine?

Output: Frederick G. Kushner

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Vice Chair of Tulane University School of Medicine?. ### Response: Frederick G. Kushner.


Instruction: Who is an Associate Professor of Medicine at Mount Sinai School of Medicine?

Output: Deborah  D. Ascheim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is an Associate Professor of Medicine at Mount Sinai School of Medicine?. ### Response: Deborah  D. Ascheim.


Instruction: Who is a Clinical Director of Research at the Philip R. Lee Institute for Health Policy Studies at UCSF?

Output: Deborah  D. Ascheim

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Clinical Director of Research at the Philip R. Lee Institute for Health Policy Studies at UCSF?. ### Response: Deborah  D. Ascheim.


Instruction: What College of Population Health is adjunct faculty?

Output: Thomas Jefferson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What College of Population Health is adjunct faculty?. ### Response: Thomas Jefferson.


Instruction: Who is the founder of IPO4Health?

Output: Alvarez

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the founder of IPO4Health?. ### Response: Alvarez.


Instruction: What is the name of the foundation that is the professor of medicine?

Output: Cleveland Clinic Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the foundation that is the professor of medicine?. ### Response: Cleveland Clinic Foundation.


Instruction: Who is the professor of medicine at LemosUT Southwestern Medical Center?

Output: James A.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of medicine at LemosUT Southwestern Medical Center?. ### Response: James A..


Instruction: What is the name of the Distinguished Chair in Clinical Care and Research held by Dr. Borah B. Diercks?

Output: Audre and Bernard Rapoport

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Distinguished Chair in Clinical Care and Research held by Dr. Borah B. Diercks?. ### Response: Audre and Bernard Rapoport.


Instruction: Where can you download the ahajournals.org article on April 28, 2023?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you download the ahajournals.org article on April 28, 2023?. ### Response: http://ahajournals.org.


Instruction: What year did e256 Stroke occur?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did e256 Stroke occur?. ### Response: 2018.


Instruction: What is the name of the patient with ICH who is prescribed an oral or transdermal antihypertensive medication or has a documented BP off medications?

Output: Numerator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the patient with ICH who is prescribed an oral or transdermal antihypertensive medication or has a documented BP off medications?. ### Response: Numerator.


Instruction: What is the time of hospital dischargeNumerator Patients who are prescribed an oral or transdermal antihypertensive medication or who have a documented BP off medications 130/80 mm Hg?

Output: Period of Assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the time of hospital dischargeNumerator Patients who are prescribed an oral or transdermal antihypertensive medication or who have a documented BP off medications 130/80 mm Hg?. ### Response: Period of Assessment.


Instruction: All patients with ICHExcluded patients: 18 y of age What is the length of stay?

Output: >120

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: All patients with ICHExcluded patients: 18 y of age What is the length of stay?. ### Response: >120.


Instruction: How long is the stay?

Output: >120

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the stay?. ### Response: >120.


Instruction: What measures are documented?

Output: Comfort measures only

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What measures are documented?. ### Response: Comfort measures only.


Instruction: What would affect the use of antihypertensive medications or a specific BP target?

Output: clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would affect the use of antihypertensive medications or a specific BP target?. ### Response: clinical trial.


Instruction: What is the single most important modifiable risk?

Output: Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the single most important modifiable risk?. ### Response: Hypertension.


Instruction: What is the single most important modifiable risk factor for recurrent stroke among patients who survive ICH?

Output: Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the single most important modifiable risk factor for recurrent stroke among patients who survive ICH?. ### Response: Hypertension.


Instruction: Long-term BP control reduces the risk of what?

Output: recurrent ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Long-term BP control reduces the risk of what?. ### Response: recurrent ICH.


Instruction: Randomized clinical trials have found early lowering of BP to be safe after spontaneous ICH.

Output: Long-term BP control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Randomized clinical trials have found early lowering of BP to be safe after spontaneous ICH.. ### Response: Long-term BP control.


Instruction: What is the name of the 2015 AHA/ASA guideline for the management of spontaneous intraacerebral hemorrhage?

Output: Guidelines for the Management of Spontaneous Intracerebral Hemorrhage”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2015 AHA/ASA guideline for the management of spontaneous intraacerebral hemorrhage?. ### Response: Guidelines for the Management of Spontaneous Intracerebral Hemorrhage”.


Instruction: What should be controlled in all patients with ICH (Class I, Level of Evidence A)?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be controlled in all patients with ICH (Class I, Level of Evidence A)?. ### Response: BP.


Instruction: What should begin immediately after ICH?

Output: Measures to control BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should begin immediately after ICH?. ### Response: Measures to control BP.


Instruction: What should be done immediately after ICH onset?

Output: Measures to control BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be done immediately after ICH onset?. ### Response: Measures to control BP.


Instruction: What is a class I, Level of Evidence A?

Output: BP should be controlled in all patients with ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class I, Level of Evidence A?. ### Response: BP should be controlled in all patients with ICH.


Instruction: What is a documented BP of 130/80 mm Hg at the time of hospital discharge?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a documented BP of 130/80 mm Hg at the time of hospital discharge?. ### Response: ≥.


Instruction: What is the percentage of patients prescribed an oral or transdermal antihypertensive medication?

Output: Per patient population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of patients prescribed an oral or transdermal antihypertensive medication?. ### Response: Per patient population.


Instruction: What is the percentage of patients prescribed an oral or transdermal antihypertensive medication at the time of hospital discharge?

Output: Per patient population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of patients prescribed an oral or transdermal antihypertensive medication at the time of hospital discharge?. ### Response: Per patient population.


Instruction: What is a documented BP of 130/80 mm Hg?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a documented BP of 130/80 mm Hg?. ### Response: ≥.


Instruction: What does not guarantee long-term BP control?

Output: Prescription of an antihypertensive agent at hospital discharge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not guarantee long-term BP control?. ### Response: Prescription of an antihypertensive agent at hospital discharge.


Instruction: What is required because an antihypertensive medication is not prescribed at discharge?

Output: Documentation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required because an antihypertensive medication is not prescribed at discharge?. ### Response: Documentation.


Instruction: What is not prescribed at hospital discharge if the BP at that time is 130/80 mm Hg?

Output: antihypertensive medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not prescribed at hospital discharge if the BP at that time is 130/80 mm Hg?. ### Response: antihypertensive medication.


Instruction: What indicates American Heart Association; ASA, American Stroke?

Output: AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates American Heart Association; ASA, American Stroke?. ### Response: AHA.


Instruction: What does NoneAHA stand for?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NoneAHA stand for?. ### Response: American Heart Association.


Instruction: What does ASA stand for??

Output: American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ASA stand for??. ### Response: American Stroke Association.


Instruction: What is BP a part of?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is BP a part of?. ### Response: blood pressure.


Instruction: Where can ahajournals.org be found?

Output: http://ahajournals.org by on April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can ahajournals.org be found?. ### Response: http://ahajournals.org by on April 28, 2023.


Instruction: What is the 2018 ACHD Guideline?

Output: April 2, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 ACHD Guideline?. ### Response: April 2, 2019.


Instruction: What is a possible cause of renal insufficiency?

Output: iron deficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible cause of renal insufficiency?. ### Response: iron deficiency.


Instruction: What are some of the palliative therapies that may be helpful?

Output: sup-plemental oxygen if systemic arterial oxygen saturation is empirically noted to rise in response, systemic antico-agulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the palliative therapies that may be helpful?. ### Response: sup-plemental oxygen if systemic arterial oxygen saturation is empirically noted to rise in response, systemic antico-agulation.


Instruction: What is sup-plemental oxygen if systemic arterial oxygen saturation is empirically noted to rise in response?

Output: Palliative therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is sup-plemental oxygen if systemic arterial oxygen saturation is empirically noted to rise in response?. ### Response: Palliative therapies.


Instruction: What causes vasodilation?

Output: high heat or humidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes vasodilation?. ### Response: high heat or humidity.


Instruction: What is limited or nonexistent?

Output: supportive data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is limited or nonexistent?. ### Response: supportive data.


Instruction: How can an-ticoagulation be beneficial?

Output: adverse as well as possible helpful effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can an-ticoagulation be beneficial?. ### Response: adverse as well as possible helpful effects.


Instruction: What has been applied to patients with ACHD with Eisen-menger syndrome with deteriorating functional ability?

Output: Mechanical circulatory and pulmonary support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been applied to patients with ACHD with Eisen-menger syndrome with deteriorating functional ability?. ### Response: Mechanical circulatory and pulmonary support.


Instruction: What are adults with Eisen-menger syndrome not standardized on?

Output: Indications for such therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are adults with Eisen-menger syndrome not standardized on?. ### Response: Indications for such therapies.


Instruction: What is helpful in the management of certain patients with Eisenmenger Syndrome?

Output: PAH medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is helpful in the management of certain patients with Eisenmenger Syndrome?. ### Response: PAH medications.


Instruction: Who should perform surgeries, cardiac catheterization, and other procedures in these patients?

Output: Section 3.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should perform surgeries, cardiac catheterization, and other procedures in these patients?. ### Response: Section 3.3.


Instruction: Section 3.4 for rec-ommendations on what?

Output: diagnostic evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Section 3.4 for rec-ommendations on what?. ### Response: diagnostic evaluation.


Instruction: Table 33 for routine testing and follow-up intervals?

Output: rec-ommendations on diagnostic evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Table 33 for routine testing and follow-up intervals?. ### Response: rec-ommendations on diagnostic evaluation.


Instruction: Right-to-left shunting through septal defects or connections between the great arteries associated with subpulmonary ventricular hypertension may be considered?

Output: Eisenmenger syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Right-to-left shunting through septal defects or connections between the great arteries associated with subpulmonary ventricular hypertension may be considered?. ### Response: Eisenmenger syndrome.


Instruction: What may be diagnosed as Eisenmenger syndrome?

Output: Right-to-left shunting through septal defects or connections between the great arteries associ-ated with subpulmonary ventricular hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be diagnosed as Eisenmenger syndrome?. ### Response: Right-to-left shunting through septal defects or connections between the great arteries associ-ated with subpulmonary ventricular hypertension.


Instruction: What may cause right-to-left shunting?

Output: RVOT obstruction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may cause right-to-left shunting?. ### Response: RVOT obstruction.


Instruction: What are some other conditions that require different treatment options?

Output: right-to-left shunting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some other conditions that require different treatment options?. ### Response: right-to-left shunting.


Instruction: Accurate diagnosis is necessary to guide what?

Output: therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Accurate diagnosis is necessary to guide what?. ### Response: therapy.


Instruction: What will not be beneficial?

Output: PAH therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will not be beneficial?. ### Response: PAH therapies.


Instruction: What will not be beneficial if the source of right-to-left shunting is RVOT obstruction?

Output: PAH therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will not be beneficial if the source of right-to-left shunting is RVOT obstruction?. ### Response: PAH therapies.


Instruction: What is the necessary treatment?

Output: allevi-ation of the RVOT obstruction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the necessary treatment?. ### Response: allevi-ation of the RVOT obstruction.


Instruction: Accurate diagnosis of Eisenmenger syndrome and exclusion of other potential con-tributors to what?

Output: right-to-left shunting or pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Accurate diagnosis of Eisenmenger syndrome and exclusion of other potential con-tributors to what?. ### Response: right-to-left shunting or pulmonary hypertension.


Instruction: What type of shunting is used to treat pulmonary hypertension?

Output: right-to-left

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of shunting is used to treat pulmonary hypertension?. ### Response: right-to-left.


Instruction: What is the use of advanced imaging?

Output: Accurate diagnosis of Eisenmenger syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use of advanced imaging?. ### Response: Accurate diagnosis of Eisenmenger syndrome.


Instruction: What is the acronym for Heart Association Task Force on Clinical Practice Guidelines?

Output: JACC Heart Fail

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Heart Association Task Force on Clinical Practice Guidelines?. ### Response: JACC Heart Fail.


Instruction: What are the names of the two groups involved in the study?

Output: Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the two groups involved in the study?. ### Response: Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.


Instruction: How is scarring measured in patients with cardiac sarcoidosis?

Output: Prognostic value of myocardial scarring on CMR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is scarring measured in patients with cardiac sarcoidosis?. ### Response: Prognostic value of myocardial scarring on CMR.


Instruction: When was the JACC Cardiovasc Imaging published?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JACC Cardiovasc Imaging published?. ### Response: 2013.


Instruction: What is the risk for sudden death in dilated cardiomyopathy?

Output: ventricular arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk for sudden death in dilated cardiomyopathy?. ### Response: ventricular arrhythmias.


Instruction: What is a systematic review and meta-analysis of ventricular arrhythmias and sudden death?

Output: dilated cardiomyopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis of ventricular arrhythmias and sudden death?. ### Response: dilated cardiomyopathy.


Instruction: What predicts death and other adverse events in suspected cardiac sarcoidosis?

Output: CMR imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts death and other adverse events in suspected cardiac sarcoidosis?. ### Response: CMR imaging.


Instruction: What does CMR imaging predict?

Output: death and other adverse events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CMR imaging predict?. ### Response: death and other adverse events.


Instruction: When did JACC Cardiovasc Imaging issue 6:501-11?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JACC Cardiovasc Imaging issue 6:501-11?. ### Response: 2013.


Instruction: What are implications for the ablation strategy in nonischemic cardiomyopathy?

Output: Contrast-enhanced MRI-derived scar patterns and associated ventricular tachycardias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implications for the ablation strategy in nonischemic cardiomyopathy?. ### Response: Contrast-enhanced MRI-derived scar patterns and associated ventricular tachycardias.


Instruction: What is the utility of cardiovascular magnetic resonance in identifying substrate for malignant ventricular arrhyth-mias?

Output: White JA, Fine NM, Gula L, et al. Utility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the utility of cardiovascular magnetic resonance in identifying substrate for malignant ventricular arrhyth-mias?. ### Response: White JA, Fine NM, Gula L, et al. Utility.


Instruction: What are the biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure?

Output: Biomarkers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure?. ### Response: Biomarkers.


Instruction: What is a brain natriuretic peptide for the prediction of?

Output: sudden cardiac death and ventricular arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a brain natriuretic peptide for the prediction of?. ### Response: sudden cardiac death and ventricular arrhythmias.


Instruction: What is a major predictor of ventricular tachyarrhythmias?

Output: B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major predictor of ventricular tachyarrhythmias?. ### Response: B-type natriuretic peptide.


Instruction: What is B-type natriuretic peptide?

Output: Amino-terminal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is B-type natriuretic peptide?. ### Response: Amino-terminal.


Instruction: What are tachyarrhythmias?

Output: ventricular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are tachyarrhythmias?. ### Response: ventricular.


Instruction: What predicts sudden death in patients with chronic heart failure?

Output: B-type natriuretic pep-tide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts sudden death in patients with chronic heart failure?. ### Response: B-type natriuretic pep-tide.


Instruction: When did Circulation. 2002:105:2392-7?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2002:105:2392-7?. ### Response: 2002.


Instruction: What is peptide and high-sensitivity C-reactive protein as predictors of?

Output: sudden cardiac death among women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is peptide and high-sensitivity C-reactive protein as predictors of?. ### Response: sudden cardiac death among women.


Instruction: What was the Circulation. 2009;119:2868-76.

Output: Amino-terminal pro-B-type natriuretic peptide and high-sensitivity C-reactive protein as predictors of sudden cardiac death among women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Circulation. 2009;119:2868-76.. ### Response: Amino-terminal pro-B-type natriuretic peptide and high-sensitivity C-reactive protein as predictors of sudden cardiac death among women.


Instruction: What is associated with sudden cardiac death risk?

Output: N-terminal pro-B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with sudden cardiac death risk?. ### Response: N-terminal pro-B-type natriuretic peptide.


Instruction: What is the name of the study that assesses the risk of sudden cardiac death in the community?

Output: the Cardiovascular Health Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that assesses the risk of sudden cardiac death in the community?. ### Response: the Cardiovascular Health Study.


Instruction: What are the results of the Cardiovascular Health Study?

Output: Cardiomyocyte injury assessed by a highly sensitive troponin assay and sudden cardiac death in the community

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the Cardiovascular Health Study?. ### Response: Cardiomyocyte injury assessed by a highly sensitive troponin assay and sudden cardiac death in the community.


Instruction: When was the J Am Coll Cardiol 62:2112-20.4.2.6?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 62:2112-20.4.2.6?. ### Response: 2013.


Instruction: What is the syndrome S4.2.6-1?

Output: Arrhythmia Syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the syndrome S4.2.6-1?. ### Response: Arrhythmia Syndromes.


Instruction: What are the mutations in genes encoding cardiac ion channels previously associated with?

Output: sudden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the mutations in genes encoding cardiac ion channels previously associated with?. ### Response: sudden.


Instruction: When was this study published?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 23, 2023.


Instruction: What was an RCT comparing the ARB candesartan with thecalcium-channel blocker amlodipine?

Output: Antihypertensive Survival Evaluation in Japan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was an RCT comparing the ARB candesartan with thecalcium-channel blocker amlodipine?. ### Response: Antihypertensive Survival Evaluation in Japan.


Instruction: What reducedprogression of CKD 4?

Output: candesartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reducedprogression of CKD 4?. ### Response: candesartan.


Instruction: How was the Telmisartan Randomized Assess-ment Study in ACE Intolerant Subjects with CardiovascularDisease studied?

Output: Insubgroup analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the Telmisartan Randomized Assess-ment Study in ACE Intolerant Subjects with CardiovascularDisease studied?. ### Response: Insubgroup analyses.


Instruction: What was the name of the RCT that included patients with vascular disease or diabetes?

Output: Telmisartan Randomized Assess-ment Study in ACE Intolerant Subjects with CardiovascularDisease (TRANSCEND

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the RCT that included patients with vascular disease or diabetes?. ### Response: Telmisartan Randomized Assess-ment Study in ACE Intolerant Subjects with CardiovascularDisease (TRANSCEND.


Instruction: What did the ARB telmisartan decrease the risk of in comparison with placebo?

Output: composite kidneyoutcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ARB telmisartan decrease the risk of in comparison with placebo?. ### Response: composite kidneyoutcome.


Instruction: What did telmisartan benefit patients with?

Output: microalbumi-nuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did telmisartan benefit patients with?. ### Response: microalbumi-nuria.


Instruction: What was associated with harm in those without microalbuminuria?

Output: telmisartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with harm in those without microalbuminuria?. ### Response: telmisartan.


Instruction: Inpatients with diabetes, ACE-Is and ARBs have been shown to prevent the development of what?

Output: macroalbuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inpatients with diabetes, ACE-Is and ARBs have been shown to prevent the development of what?. ### Response: macroalbuminuria.


Instruction: What was the name of the large RCT that examined the effects of the ACE-I lisinopril, thiazidechlorthalidone, and dihydropyridine calcium-channelblocker amlodipine in individuals 455 years of age?

Output: The Antihypertensive and Lipid-Lowering Treatment toPrevent Heart Attack Trial (ALLHAT)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the large RCT that examined the effects of the ACE-I lisinopril, thiazidechlorthalidone, and dihydropyridine calcium-channelblocker amlodipine in individuals 455 years of age?. ### Response: The Antihypertensive and Lipid-Lowering Treatment toPrevent Heart Attack Trial (ALLHAT).


Instruction: What is the dihydropyridine calcium-channelblocker amlodipine?

Output: hypertension and at least one other CVD risk factor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the dihydropyridine calcium-channelblocker amlodipine?. ### Response: hypertension and at least one other CVD risk factor.


Instruction: What was not shown a benefit for doubling of creatinine or kidney failure when compared with chlorthalidone?

Output: Lisinopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not shown a benefit for doubling of creatinine or kidney failure when compared with chlorthalidone?. ### Response: Lisinopril.


Instruction: What did ALLHAT not allow the use of with an ACE-I?

Output: diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did ALLHAT not allow the use of with an ACE-I?. ### Response: diuretic.


Instruction: What is frequently required in clinical practice to achieve adequate BP control?

Output: ACE-I with a diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is frequently required in clinical practice to achieve adequate BP control?. ### Response: ACE-I with a diuretic.


Instruction: The diuretic arm inALLHAT achieved better what?

Output: BP control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The diuretic arm inALLHAT achieved better what?. ### Response: BP control.


Instruction: What made comparison ofagents more difficult to interpret?

Output: the diuretic arm inALLHAT achieved better BP control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What made comparison ofagents more difficult to interpret?. ### Response: the diuretic arm inALLHAT achieved better BP control.


Instruction: What was not measured in the enrolled subjects?

Output: uria status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not measured in the enrolled subjects?. ### Response: uria status.


Instruction: What was most likely below themicroalbuminuria cutoff?

Output: proteinuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was most likely below themicroalbuminuria cutoff?. ### Response: proteinuria.


Instruction: How many RCTs have focused on CVD outcomes in CKD patients without diabetesmellitus?

Output: few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs have focused on CVD outcomes in CKD patients without diabetesmellitus?. ### Response: few.


Instruction: What did HOPE show for CVDoutcomes in patients randomized to ramipril?

Output: a beneﬁt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did HOPE show for CVDoutcomes in patients randomized to ramipril?. ### Response: a beneﬁt.


Instruction: What was the creatinine level of non-diabetic individuals?

Output: 41.4 mg/dl

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the creatinine level of non-diabetic individuals?. ### Response: 41.4 mg/dl.


Instruction: What is the name of the drug used to treat microalbuminuria in non-diabetic individuals?

Output: Perindopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat microalbuminuria in non-diabetic individuals?. ### Response: Perindopril.


Instruction: What is the advantage of this approach?

Output: it produces summary estimates of sensitivity and specificity that account for the correlation between the 2 statistics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the advantage of this approach?. ### Response: it produces summary estimates of sensitivity and specificity that account for the correlation between the 2 statistics.


Instruction: What account for the correlation between the 2 statistics?

Output: sensitivity and specificity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What account for the correlation between the 2 statistics?. ### Response: sensitivity and specificity.


Instruction: What method uses logistic regression on the true positives, true negatives, false positives and false negatives reported in the studies?

Output: bivariat e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What method uses logistic regression on the true positives, true negatives, false positives and false negatives reported in the studies?. ### Response: bivariat e.


Instruction: What are the overall sensitivity and specificity and confidence regions?

Output: Overall sensitivity and specificity and confidence regions were plotted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the overall sensitivity and specificity and confidence regions?. ### Response: Overall sensitivity and specificity and confidence regions were plotted.


Instruction: How were sensitivity and specificity and confidence regions plotted?

Output: using methods outlined by Novielli 2010.284

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were sensitivity and specificity and confidence regions plotted?. ### Response: using methods outlined by Novielli 2010.284.


Instruction: What were the 95% CIs reported in the clinical evidence summary table?

Output: Pooled sensitivity and specificity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the 95% CIs reported in the clinical evidence summary table?. ### Response: Pooled sensitivity and specificity.


Instruction: How many studies did each study have?

Output: fewer than 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did each study have?. ### Response: fewer than 3.


Instruction: How many studies were there?

Output: fewer than 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were there?. ### Response: fewer than 3.


Instruction: What criteria were used for evaluating AUCs?

Output: followin g criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria were used for evaluating AUCs?. ### Response: followin g criteria.


Instruction: How are AUCs evaluated?

Output: followin g criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are AUCs evaluated?. ### Response: followin g criteria.


Instruction: What is a very poor AUC?

Output: worse than chance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a very poor AUC?. ### Response: worse than chance.


Instruction: How is an excellent or perfect test?

Output: –1.00

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is an excellent or perfect test?. ### Response: –1.00.


Instruction: What was presented separately for discrimination and calibration?

Output: Evidence reviews on risk prediction rules or risk prediction tool results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was presented separately for discrimination and calibration?. ### Response: Evidence reviews on risk prediction rules or risk prediction tool results.


Instruction: What were the principles of data synthesis for diagnostic accuracy studies outlined in?

Output: section 4.3.3.2.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the principles of data synthesis for diagnostic accuracy studies outlined in?. ### Response: section 4.3.3.2.2.


Instruction: What were diagnostic accuracy studies described in?

Output: section 4.3.3.2.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were diagnostic accuracy studies described in?. ### Response: section 4.3.3.2.2.


Instruction: What was presented separately to the discrimination data?

Output: Calibration data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was presented separately to the discrimination data?. ### Response: Calibration data.


Instruction: How were the results presented for each study separately?

Output: the quality rating for the study and modified GRADE assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the results presented for each study separately?. ### Response: the quality rating for the study and modified GRADE assessment.


Instruction: What were the main findings for each included paper identified and thematic analysis methods used to synthesise?

Output: Data synthesis for qualitative study reviews  The main findings for each included paper  were identified and thematic analysis methods were used to synthesise this information into broad over arching themes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the main findings for each included paper identified and thematic analysis methods used to synthesise?. ### Response: Data synthesis for qualitative study reviews  The main findings for each included paper  were identified and thematic analysis methods were used to synthesise this information into broad over arching themes.


Instruction: What was used to summarise the information into the main review findings?

Output: thematic analysis methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to summarise the information into the main review findings?. ### Response: thematic analysis methods.


Instruction: What was presented in the form of a narrative summary detailing the evidence from the relevant papers and how this informed the overall review finding?

Output: The evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was presented in the form of a narrative summary detailing the evidence from the relevant papers and how this informed the overall review finding?. ### Response: The evidence.


Instruction: What was the level of confidence for the review finding?

Output: –0.80: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the level of confidence for the review finding?. ### Response: –0.80: moderate.


Instruction: What was produced with the succinct summary statements for each review finding including the associated quality assessment?

Output: A summary evidence table

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was produced with the succinct summary statements for each review finding including the associated quality assessment?. ### Response: A summary evidence table.


Instruction: How was the evidence presented?

Output: in the form of a narrative summary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the evidence presented?. ### Response: in the form of a narrative summary.


Instruction: What toolbox was used to evaluate the quality of the evidence?

Output: Grading of Recommendations Assessment, Development and Evaluation (GRADE)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What toolbox was used to evaluate the quality of the evidence?. ### Response: Grading of Recommendations Assessment, Development and Evaluation (GRADE).


Instruction: How did the evidence for outcomes from the included RCTs and, where appropriate, non-randomised intervention studies be evaluated?

Output: a narrative summary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the evidence for outcomes from the included RCTs and, where appropriate, non-randomised intervention studies be evaluated?. ### Response: a narrative summary.


Instruction: What does GRADE stand for?

Output: Grading of Recommendations Assessment, Development and Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GRADE stand for?. ### Response: Grading of Recommendations Assessment, Development and Evaluation.


Instruction: What is the name of the toolbox developed by the international GRADE working group?

Output: Grading of Recommendations Assessment, Development and Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the toolbox developed by the international GRADE working group?. ### Response: Grading of Recommendations Assessment, Development and Evaluation.


Instruction: What is reduced in patients with aortic stenosis?

Output: left ventricular ejec-tion fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reduced in patients with aortic stenosis?. ### Response: left ventricular ejec-tion fraction.


Instruction: What is the association between left ventricular ejection fraction and mortality?

Output: Relationship be-tween left ventricular ejection fraction and mortality in asymptomatic and minimally symptomatic patients with severe aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between left ventricular ejection fraction and mortality?. ### Response: Relationship be-tween left ventricular ejection fraction and mortality in asymptomatic and minimally symptomatic patients with severe aortic stenosis.


Instruction: What is ejection fraction and mortality in asymptomatic and minimally symptomatic patients with severe aortic stenosis?

Output: left ventricular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ejection fraction and mortality in asymptomatic and minimally symptomatic patients with severe aortic stenosis?. ### Response: left ventricular.


Instruction: What is Rosenhek R, Binder T, Porenta G, et al?

Output: Predictors of outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Rosenhek R, Binder T, Porenta G, et al?. ### Response: Predictors of outcome.


Instruction: How many adults had asymptomatic, hemodynamically significant aortic stenosis during pro-long follow-up?

Output: 622

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many adults had asymptomatic, hemodynamically significant aortic stenosis during pro-long follow-up?. ### Response: 622.


Instruction: What was the outcome of the prospective study of valvular, aartic, and exercise predictors of outcome?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the prospective study of valvular, aartic, and exercise predictors of outcome?. ### Response: mortality.


Instruction: What is hemodynamically significant during pro-long follow-up?

Output: aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hemodynamically significant during pro-long follow-up?. ### Response: aortic stenosis.


Instruction: What is the importance of the valvular, arterial and ventricular interplay in asymptomatic moderate to severe aortic stenosis?

Output: Risk stratification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the importance of the valvular, arterial and ventricular interplay in asymptomatic moderate to severe aortic stenosis?. ### Response: Risk stratification.


Instruction: What is the difference between early surgery and conventional treatment in asymptomatic very severe aortic stenosis?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between early surgery and conventional treatment in asymptomatic very severe aortic stenosis?. ### Response: mortality.


Instruction: Circulation. 2010;121:1502-9.

Output: 17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2010;121:1502-9.. ### Response: 17.


Instruction: Tribouilloy C, Lévy F, Rusinaru D, et al. Outcome after what?

Output: aortic valve re-placement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tribouilloy C, Lévy F, Rusinaru D, et al. Outcome after what?. ### Response: aortic valve re-placement.


Instruction: What is the contrac-tile reserve on dobutamine stress echocardiography?

Output: Low-output

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the contrac-tile reserve on dobutamine stress echocardiography?. ### Response: Low-output.


Instruction: What was the J Am Coll Cardiol. 2009;53:1865–73?

Output: Outcome after aortic valve re-placement for low-flow/low-gradient aortic stenosis without contrac-tile reserve on dobutamine stress echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol. 2009;53:1865–73?. ### Response: Outcome after aortic valve re-placement for low-flow/low-gradient aortic stenosis without contrac-tile reserve on dobutamine stress echocardiography.


Instruction: How did the PARTNER trial compare mortality and outcomes?

Output: Predictors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the PARTNER trial compare mortality and outcomes?. ### Response: Predictors.


Instruction: What is the name of the randomized clinical trial that evaluated flow after trans-catheter aortic valve replacement in patients with low-flow stenosis?

Output: PARTNER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial that evaluated flow after trans-catheter aortic valve replacement in patients with low-flow stenosis?. ### Response: PARTNER.


Instruction: How many patients were evaluated in the PARTNER randomized trial?

Output: 622

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were evaluated in the PARTNER randomized trial?. ### Response: 622.


Instruction: What was the primary outcome of the study?

Output: Clinical, echocardiographic, and exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome of the study?. ### Response: Clinical, echocardiographic, and exercise.


Instruction: What is the surgical outcome of low-flow low-gradient aortic stenosis?

Output: mid-term results after isolated aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the surgical outcome of low-flow low-gradient aortic stenosis?. ### Response: mid-term results after isolated aortic valve replacement.


Instruction: What does Eur J Cardiothorac Surg. 2016:49:1685–90?

Output: Low-flow low-gradient aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Eur J Cardiothorac Surg. 2016:49:1685–90?. ### Response: Low-flow low-gradient aortic stenosis.


Instruction: What is the clinical utility of the dobutamine challenge in patients with depressed left ventricular systolic func-tion?

Output: Low-output, low-gradi-ent aortic stenosis in patients with depressed left ventricular systolic func-tion: the clinical utility of the dobutamine challenge in the catheterization laboratory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical utility of the dobutamine challenge in patients with depressed left ventricular systolic func-tion?. ### Response: Low-output, low-gradi-ent aortic stenosis in patients with depressed left ventricular systolic func-tion: the clinical utility of the dobutamine challenge in the catheterization laboratory.


Instruction: What is a patient with low-flow, low-gradient severe aortic valve stenosis assigned to?

Output: treatment modality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a patient with low-flow, low-gradient severe aortic valve stenosis assigned to?. ### Response: treatment modality.


Instruction: What is the clinical utility of the dobutamine challenge in the catheterization laboratory?

Output: Low-output, low-gradi-ent aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical utility of the dobutamine challenge in the catheterization laboratory?. ### Response: Low-output, low-gradi-ent aortic stenosis.


Instruction: Circulation. 2002;106:809–13.

Output: Nishimura

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2002;106:809–13.. ### Response: Nishimura.


Instruction: What is low-gradient aortic stenosis?

Output: low-flow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low-gradient aortic stenosis?. ### Response: low-flow.


Instruction: When did ACC/AHA/SCAI Focused Update on Primary PCI1243 occur?

Output: MARCH 15, 2016:1235 –50 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did ACC/AHA/SCAI Focused Update on Primary PCI1243 occur?. ### Response: MARCH 15, 2016:1235 –50 2015.


Instruction: How many reasons are there for patients to be anticoagulated?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many reasons are there for patients to be anticoagulated?. ### Response: two.


Instruction: Why is a diagnosis of subsegmentalPE more likely to be false-positive than adiagnosis of PE in the segmental or more proximalpulmonary arteries?

Output: abnormalities are small

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is a diagnosis of subsegmentalPE more likely to be false-positive than adiagnosis of PE in the segmental or more proximalpulmonary arteries?. ### Response: abnormalities are small.


Instruction: What is likely to have arisen from a smallDVT?

Output: truesubsegmental PE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to have arisen from a smallDVT?. ### Response: truesubsegmental PE.


Instruction: The risk of progressive or recurrent VTE withoutanticoagulation is expected to be lower than in patientswith a larger PE?

Output: because a truesubsegmental PE is likely to have arisen from a smallDVT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The risk of progressive or recurrent VTE withoutanticoagulation is expected to be lower than in patientswith a larger PE?. ### Response: because a truesubsegmental PE is likely to have arisen from a smallDVT.


Instruction: What is the risk of progressive or recurrent VTE in patients with subsegmental PE?

Output: high enough to justifyanticoagulation in patients with subsegmental PE isuncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of progressive or recurrent VTE in patients with subsegmental PE?. ### Response: high enough to justifyanticoagulation in patients with subsegmental PE isuncertain.


Instruction: There is high-quality evidence for the ef ficacy andsafety of what?

Output: anticoagulant therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is high-quality evidence for the ef ficacy andsafety of what?. ### Response: anticoagulant therapy.


Instruction: In patients with subsegmental PE, what isuncertain?

Output: Whether the risk of progressiveor recurrent VTE is high enough to justifyanticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with subsegmental PE, what isuncertain?. ### Response: Whether the risk of progressiveor recurrent VTE is high enough to justifyanticoagulation.


Instruction: In retrospective reports, how many episodes of recurrentVTE were there?

Output: 60

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In retrospective reports, how many episodes of recurrentVTE were there?. ### Response: 60.