Instruction: What is a combination of noninvasive coronary angiography and myocardial perfusion?

Output: Diagnostic performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a combination of noninvasive coronary angiography and myocardial perfusion?. ### Response: Diagnostic performance.


Instruction: What criteria should be applied to patients at risk of ACS following non-cardiac surgery?

Output: Third Universal Definition of MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria should be applied to patients at risk of ACS following non-cardiac surgery?. ### Response: Third Universal Definition of MI.


Instruction: What may routine monitoring of troponins and ECGs be performed in?

Output: patients at risk of ACS following non-cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may routine monitoring of troponins and ECGs be performed in?. ### Response: patients at risk of ACS following non-cardiac surgery.


Instruction: As the sensitivity of what assays improves, the frequency of what increases?

Output: identifying perioperative MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: As the sensitivity of what assays improves, the frequency of what increases?. ### Response: identifying perioperative MI.


Instruction: As the sensitivity of troponin assays improves, the frequency of identifying perioperative MI will increase.

Output: In patients at risk of ACS following non-cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: As the sensitivity of troponin assays improves, the frequency of identifying perioperative MI will increase.. ### Response: In patients at risk of ACS following non-cardiac surgery.


Instruction: How many patients were randomized to extended-release metoprolol versus placebo in the POISE trial?

Output: 8351

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were randomized to extended-release metoprolol versus placebo in the POISE trial?. ### Response: 8351.


Instruction: What percentage of patients in the control group had a perioperational MI typically occurring within 48 hours?

Output: 5.7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in the control group had a perioperational MI typically occurring within 48 hours?. ### Response: 5.7%.


Instruction: How long did perioperative MI typically occur?

Output: within 48 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did perioperative MI typically occur?. ### Response: within 48 hours.


Instruction: What was not associated with ischemic symptoms?

Output: perioperative MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not associated with ischemic symptoms?. ### Response: perioperative MI.


Instruction: When was this article downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: April 28, 2023.


Instruction: What should a patient refrain from before repeat surgical intervention is considered?

Output: actions that risk reinfection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient refrain from before repeat surgical intervention is considered?. ### Response: actions that risk reinfection.


Instruction: What is reasonable in patients with IE who present with recurrent emboli and persistent vegetations despite appropriate antibiotic therapy?

Output: early surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in patients with IE who present with recurrent emboli and persistent vegetations despite appropriate antibiotic therapy?. ### Response: early surgery.


Instruction: What is reasonable in patients with native left-sided valve endocarditis who exhibit mobile vegetations >10 mm in length?

Output: early surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in patients with native left-sided valve endocarditis who exhibit mobile vegetations >10 mm in length?. ### Response: early surgery.


Instruction: What may occur during initial hospitalization and before completion of a full therapeutic course of antibiotics?

Output: early surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may occur during initial hospitalization and before completion of a full therapeutic course of antibiotics?. ### Response: early surgery.


Instruction: What may be considered before completion of a full therapeutic course of antibiotics?

Output: early surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered before completion of a full therapeutic course of antibiotics?. ### Response: early surgery.


Instruction: In patients with IE and an indication for surgery who have suffered a stroke but have no evidence of intracranial hemorrhage or extensive neurological damage, operation without delay is considered?

Output: 68–70 2b B-NR12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with IE and an indication for surgery who have suffered a stroke but have no evidence of intracranial hemorrhage or extensive neurological damage, operation without delay is considered?. ### Response: 68–70 2b B-NR12.


Instruction: What may be considered for patients with IE and major ischemic stroke with extensive neurological damage or intracranial hemorrhage?

Output: delaying valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for patients with IE and major ischemic stroke with extensive neurological damage or intracranial hemorrhage?. ### Response: delaying valve surgery.


Instruction: How long is it recommended to delay valve surgery?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it recommended to delay valve surgery?. ### Response: 4 weeks.


Instruction: What type of MDT is required for patients who have IE?

Output: Heart Valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of MDT is required for patients who have IE?. ### Response: Heart Valve.


Instruction: If the patient is hemodynamically stable, delaying valve surgery for at least how long is considered?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the patient is hemodynamically stable, delaying valve surgery for at least how long is considered?. ### Response: 4 weeks.


Instruction: What is required for management of patients with IE?

Output: Heart Valve MDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required for management of patients with IE?. ### Response: Heart Valve MDT.


Instruction: What is a Heart Valve MDT supplemented by?

Output: inclusion of infectious disease and neurology specialists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Heart Valve MDT supplemented by?. ### Response: inclusion of infectious disease and neurology specialists.


Instruction: In patients with implanted implants, what are indications for early surgery?

Output: risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with implanted implants, what are indications for early surgery?. ### Response: risks.


Instruction: What is recurrent emboli?

Output: with persistent vegetations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recurrent emboli?. ### Response: with persistent vegetations.


Instruction: In patients with implanted electronic devices, infection of the entire system is likely even if it appears confined to the leads on imaging?

Output: removal of the entire system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with implanted electronic devices, infection of the entire system is likely even if it appears confined to the leads on imaging?. ### Response: removal of the entire system.


Instruction: What mandates removal of the whole system to eradicate the infection?

Output: implanted electronic devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What mandates removal of the whole system to eradicate the infection?. ### Response: implanted electronic devices.


Instruction: What is not a contra-indication in patients with an indication for early surgery?

Output: a cerebral embolic event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not a contra-indication in patients with an indication for early surgery?. ### Response: a cerebral embolic event.


Instruction: What type of damage or intracranial hemorrhage is not considered a complication of IE?

Output: neurological

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of damage or intracranial hemorrhage is not considered a complication of IE?. ### Response: neurological.


Instruction: Where is IE best managed?

Output: in an environment with ready access to specialists in the fields of cardiology, car -diothoracic surgery, and infectious disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is IE best managed?. ### Response: in an environment with ready access to specialists in the fields of cardiology, car -diothoracic surgery, and infectious disease.


Instruction: What has been developed to predict surgical risk in patients with IE?

Output: A risk-scoring system using the STS database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been developed to predict surgical risk in patients with IE?. ### Response: A risk-scoring system using the STS database.


Instruction: What is the risk-scoring system using the STS database?

Output: to predict surgical risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk-scoring system using the STS database?. ### Response: to predict surgical risk.


Instruction: What is the purpose of the risk in patients with IE to help better counsel patients and more objec-tively define the risks associated with surgery?

Output: A risk-scoring system using the STS database has been developed to predict surgical risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of the risk in patients with IE to help better counsel patients and more objec-tively define the risks associated with surgery?. ### Response: A risk-scoring system using the STS database has been developed to predict surgical risk.


Instruction: One trial noted that even when surgery is indicated, women were less likely to undergo a surgical procedure than men (26%) versus what percentage of men?

Output: 47%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: One trial noted that even when surgery is indicated, women were less likely to undergo a surgical procedure than men (26%) versus what percentage of men?. ### Response: 47%).


Instruction: Women had higher in-hospital and what type of risk?

Output: 1-year mortality rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Women had higher in-hospital and what type of risk?. ### Response: 1-year mortality rates.


Instruction: What was the difference between women and men in mortality rates?

Output: 26% versus 47%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between women and men in mortality rates?. ### Response: 26% versus 47%).


Instruction: What did women have higher in-hospital and 1-year mortality rates than men?

Output: similar comorbidities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did women have higher in-hospital and 1-year mortality rates than men?. ### Response: similar comorbidities.


Instruction: How long after symptom onset may emergency CABG be considered in STEMI patients?

Output: 6 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after symptom onset may emergency CABG be considered in STEMI patients?. ### Response: 6 hours.


Instruction: What is the level of evidence for CABG in the acute phase?

Output: C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for CABG in the acute phase?. ### Response: C.


Instruction: What is C)CABG used for other than for cardiogenic shock?

Output: acute phase of STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is C)CABG used for other than for cardiogenic shock?. ### Response: acute phase of STEMI.


Instruction: What type of anatomy is not amenable to PCI?

Output: coronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of anatomy is not amenable to PCI?. ### Response: coronary.


Instruction: When is CABG indicated for failed PCI or for surgical repair of a mechanical defect?

Output: at the time of surgical repair of a mechanical defect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is CABG indicated for failed PCI or for surgical repair of a mechanical defect?. ### Response: at the time of surgical repair of a mechanical defect.


Instruction: What is a mechanical defect?

Output: ventricular septal, papillary muscle, or free-wall rupture

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a mechanical defect?. ### Response: ventricular septal, papillary muscle, or free-wall rupture.


Instruction: What was a potential excess mortality risk for CABG when performed early after STEMI?

Output: myocardial injury from cardiopulmonary bypass, aortic cross-clamping, and cardioplegic arrest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a potential excess mortality risk for CABG when performed early after STEMI?. ### Response: myocardial injury from cardiopulmonary bypass, aortic cross-clamping, and cardioplegic arrest.


Instruction: What may lead to improved survival rates after CABG in the acute hospital phase?

Output: contemporary modifications to the standard operative approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may lead to improved survival rates after CABG in the acute hospital phase?. ### Response: contemporary modifications to the standard operative approach.


Instruction: What are some of the modern modifications to the standard operative approach?

Output: on-pump beating-heart surgery, off-pump techniques, or adjunctive temporary mechanical circulatory support devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the modern modifications to the standard operative approach?. ### Response: on-pump beating-heart surgery, off-pump techniques, or adjunctive temporary mechanical circulatory support devices.


Instruction: What should not be withheld before urgent CABG?

Output: Aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be withheld before urgent CABG?. ### Response: Aspirin.


Instruction: How long before urgent on-pump CABG should clopidogrel or ticagrelor be discontinued?

Output: 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before urgent on-pump CABG should clopidogrel or ticagrelor be discontinued?. ### Response: 24 hours.


Instruction: What should be discontinued at least 2 to 4 hours before urgent CABG?

Output: Short-acting intravenous GP IIb/IIIa receptor antag-onists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be discontinued at least 2 to 4 hours before urgent CABG?. ### Response: Short-acting intravenous GP IIb/IIIa receptor antag-onists.


Instruction: How long before urgent on-pump CABG should abciximab be discontinued?

Output: 12 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before urgent on-pump CABG should abciximab be discontinued?. ### Response: 12 hours.


Instruction: What should be discontinued at least 12 hours before urgent CABG?

Output: Abciximab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be discontinued at least 12 hours before urgent CABG?. ### Response: Abciximab.


Instruction: What is the level of evidence for urgent off-pump CABG within 24 hours of clopido-grel or ticagrelor administration?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for urgent off-pump CABG within 24 hours of clopido-grel or ticagrelor administration?. ### Response: B.


Instruction: What might be considered within 5 days of clopidogrel or ti-cagrelor administration?

Output: Urgent CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered within 5 days of clopidogrel or ti-cagrelor administration?. ### Response: Urgent CABG.


Instruction: What might the benefits of prompt revascularization outweigh the risks of bleeding?

Output: Urgent off-pump CABG within 24 hours of clopido-grel or ticagrelor administration might be consid-ered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might the benefits of prompt revascularization outweigh the risks of bleeding?. ### Response: Urgent off-pump CABG within 24 hours of clopido-grel or ticagrelor administration might be consid-ered.


Instruction: How long before CABG were patients exposed to clopidogrel?

Output: 5 to 7 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before CABG were patients exposed to clopidogrel?. ### Response: 5 to 7 days.


Instruction: How long after CABG did some reports suggest that it might be reasonable to proceed with urgent surgery?

Output: 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after CABG did some reports suggest that it might be reasonable to proceed with urgent surgery?. ### Response: 24 hours.


Instruction: What may be pos-sible when off-pump revascularization is planned?

Output: Shorter delays to urgent surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be pos-sible when off-pump revascularization is planned?. ### Response: Shorter delays to urgent surgery.


Instruction: How many patients in CLARITY-TIMI had urgent surgery within a shorter time frame?

Output: 136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients in CLARITY-TIMI had urgent surgery within a shorter time frame?. ### Response: 136.


Instruction: What may outweigh the risks of bleeding?

Output: the benefits of prompt revascular -ization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may outweigh the risks of bleeding?. ### Response: the benefits of prompt revascular -ization.


Instruction: What is planned for off-pump revascularization?

Output: Shorter delays to urgent surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is planned for off-pump revascularization?. ### Response: Shorter delays to urgent surgery.


Instruction: How many patients underwent CABG within 5 days of clopidogrel exposure?

Output: 136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent CABG within 5 days of clopidogrel exposure?. ### Response: 136.


Instruction: What does smoking cessation reduce in mortality in smokers?

Output: 15% over 14 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does smoking cessation reduce in mortality in smokers?. ### Response: 15% over 14 years.


Instruction: What is the definition of a body mass index 30 kg/m2?

Output: obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of a body mass index 30 kg/m2?. ### Response: obesity.


Instruction: How much of the adult US population is obese?

Output: ≈30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the adult US population is obese?. ### Response: ≈30%.


Instruction: How much of the adult US population falls into this category in recent years?

Output: ≈30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the adult US population falls into this category in recent years?. ### Response: ≈30%.


Instruction: What is the positive rela-tionship between obesity and BP well documented?

Output: 39–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the positive rela-tionship between obesity and BP well documented?. ### Response: 39–.


Instruction: How much more likely are obese adults to be hypertensive compared with nonobese adults?

Output: ≈3 times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much more likely are obese adults to be hypertensive compared with nonobese adults?. ### Response: ≈3 times.


Instruction: What may explain >60% of hypertension in adults?

Output: increased adiposity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may explain >60% of hypertension in adults?. ### Response: increased adiposity.


Instruction: What is considered a major risk factor for poor BP control in hypertensive patients?

Output: obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered a major risk factor for poor BP control in hypertensive patients?. ### Response: obesity.


Instruction: What is RAAS?

Output: renin-angiotensin-aldosterone system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is RAAS?. ### Response: renin-angiotensin-aldosterone system.


Instruction: There is no acceptable guideline on the antihypertensive drug of choice for the management of hypertension among obese patients?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no acceptable guideline on the antihypertensive drug of choice for the management of hypertension among obese patients?. ### Response: 3.


Instruction: Why do investigators consider ACE inhibitors the drugs of choice?

Output: their capacity to increase insulin sensitivity and thus reduce the risk of diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do investigators consider ACE inhibitors the drugs of choice?. ### Response: their capacity to increase insulin sensitivity and thus reduce the risk of diabetes mellitus.


Instruction: What does thiazide diuretics do in obesity-related hypertension?

Output: lowering BP and improving cardiovascular out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does thiazide diuretics do in obesity-related hypertension?. ### Response: lowering BP and improving cardiovascular out-comes.


Instruction: What is the capacity of adequate BP control in obesity related hypertension?

Output: lifestyle interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the capacity of adequate BP control in obesity related hypertension?. ### Response: lifestyle interventions.


Instruction: Which drugs are associated with increased risk of diabetes mellitus?

Output: thiazide diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drugs are associated with increased risk of diabetes mellitus?. ### Response: thiazide diuretics.


Instruction: What is the efficacy of thiazide diuretics in lowering BP and improving cardiovascular out-comes in obese hypertensive patients?

Output: well established

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the efficacy of thiazide diuretics in lowering BP and improving cardiovascular out-comes in obese hypertensive patients?. ### Response: well established.


Instruction: -Blockers also have adverse effects on glucose metabolism but have led to significant improvement in what?

Output: BP in obese

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: -Blockers also have adverse effects on glucose metabolism but have led to significant improvement in what?. ### Response: BP in obese.


Instruction: What do -blockers decrease in obese patients?

Output: renin activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do -blockers decrease in obese patients?. ### Response: renin activity.


Instruction: What are renin activity and cardiac output often elevated in?

Output: obese patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are renin activity and cardiac output often elevated in?. ### Response: obese patients.


Instruction: Why is enthusiasm for the use of a  blocker dampened by their negative profile on stroke outcomes?

Output: placebo and other antihypertensive drug classes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is enthusiasm for the use of a  blocker dampened by their negative profile on stroke outcomes?. ### Response: placebo and other antihypertensive drug classes.


Instruction: What are antihypertensive drug classes?

Output: placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are antihypertensive drug classes?. ### Response: placebo.


Instruction: What is abundant evidence in support of the effectiveness of lifestyle interventions in improving BP control?

Output: 49There is abundant evidence in support of the effectiveness of lifestyle interventions in improving BP control among obese hypertensive patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is abundant evidence in support of the effectiveness of lifestyle interventions in improving BP control?. ### Response: 49There is abundant evidence in support of the effectiveness of lifestyle interventions in improving BP control among obese hypertensive patients.


Instruction: What do adults need to do to lose weight?

Output: identi-fying

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do adults need to do to lose weight?. ### Response: identi-fying.


Instruction: What is the AHA/ACC guidelines docu-ment on?

Output: lifestyle management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHA/ACC guidelines docu-ment on?. ### Response: lifestyle management.


Instruction: What do AHA/ACC guidelines docu-ment on?

Output: lifestyle management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do AHA/ACC guidelines docu-ment on?. ### Response: lifestyle management.


Instruction: What are the two main topics of the guidelines?

Output: matching treatment benefits with risk profiles, diets for weight loss, lifestyle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two main topics of the guidelines?. ### Response: matching treatment benefits with risk profiles, diets for weight loss, lifestyle.


Instruction: What type of computed tomography is used during exercise in patients with normal rest electrocardiographic results?

Output: single-photon emission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of computed tomography is used during exercise in patients with normal rest electrocardiographic results?. ### Response: single-photon emission.


Instruction: When did Fihn et al Stable Ischemic Heart Disease: Full Text e437 download from http://ahajournals.org by?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Fihn et al Stable Ischemic Heart Disease: Full Text e437 download from http://ahajournals.org by?. ### Response: May 1, 2023.


Instruction: Does ranolazine require dose adjustment for age, sex, New York Heart Association class I-IV heart failure, ordiabetes mellitus?

Output: does not require dosage adjustment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Does ranolazine require dose adjustment for age, sex, New York Heart Association class I-IV heart failure, ordiabetes mellitus?. ### Response: does not require dosage adjustment.


Instruction: Plasma concentrations of ranolinazine are increased by up to what percentage in patients with Stage 4 CKD?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Plasma concentrations of ranolinazine are increased by up to what percentage in patients with Stage 4 CKD?. ### Response: 50%.


Instruction: What is contraindicated for patients with clinically significant hepatic impairment?

Output: Ranolazine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is contraindicated for patients with clinically significant hepatic impairment?. ### Response: Ranolazine.


Instruction: Why is ranolazine contraindicated in combination with potentinhibitors of the CYP3A4 pathway?

Output: does not require dosage adjustment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is ranolazine contraindicated in combination with potentinhibitors of the CYP3A4 pathway?. ### Response: does not require dosage adjustment.


Instruction: What does HIV stand for?

Output: human immunodef i-ciency virus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HIV stand for?. ### Response: human immunodef i-ciency virus.


Instruction: What does diltiazem increase in ranolazine plasma levels?

Output: 1.5-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does diltiazem increase in ranolazine plasma levels?. ### Response: 1.5-fold.


Instruction: Itraconazole, clarithromycin, and certain HIV protease in hibitors are examples of what?

Output: potentinhibitors of the CYP3A4 pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Itraconazole, clarithromycin, and certain HIV protease in hibitors are examples of what?. ### Response: potentinhibitors of the CYP3A4 pathway.


Instruction: What is an example of a moderate inhibitor of CYP3A?

Output: diltiazem, verapamil, aprepitant, erythromycin, f lucona-zole, or grapefruit juice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a moderate inhibitor of CYP3A?. ### Response: diltiazem, verapamil, aprepitant, erythromycin, f lucona-zole, or grapefruit juice.


Instruction: What should the dose of ranolazine be?

Output: 500 mg twice daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the dose of ranolazine be?. ### Response: 500 mg twice daily.


Instruction: How much increase is there in plasma levels of ranalazine?

Output: 1.5-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increase is there in plasma levels of ranalazine?. ### Response: 1.5-fold.


Instruction: What increases the plasma concentration of simvastatin a nd itsactive metabolite 2-fold?

Output: Co-administration of ranolazine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the plasma concentration of simvastatin a nd itsactive metabolite 2-fold?. ### Response: Co-administration of ranolazine.


Instruction: How much does the co-administration of ranolazine with sim va-statin increase?

Output: 2-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does the co-administration of ranolazine with sim va-statin increase?. ### Response: 2-fold.


Instruction: Digoxin plasma concentrations are reincreased 1.5-fold with what dose?

Output: 0.125 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Digoxin plasma concentrations are reincreased 1.5-fold with what dose?. ### Response: 0.125 mg daily.


Instruction: What is ranolazine well tolerated for?

Output: the major adverse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ranolazine well tolerated for?. ### Response: the major adverse effects.


Instruction: What is the incidence of syncope?

Output: /H110211%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence of syncope?. ### Response: /H110211%..


Instruction: How much digoxin do you take daily?

Output: 0.125 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much digoxin do you take daily?. ### Response: 0.125 mg.


Instruction: What type of agent is not currently available in the United States4.4.3.1.5.1?

Output: Antianginal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of agent is not currently available in the United States4.4.3.1.5.1?. ### Response: Antianginal.


Instruction: Nicorandil is a nicotinamide esterwith a dual mechanism of action what?

Output: It activates adenosinetriphosphate–sensitive potassium channels and promotes sys-temic venous and coronary vasodilation through a nitratemoiety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nicorandil is a nicotinamide esterwith a dual mechanism of action what?. ### Response: It activates adenosinetriphosphate–sensitive potassium channels and promotes sys-temic venous and coronary vasodilation through a nitratemoiety.


Instruction: What does nicorandilare not exhibit effects on?

Output: contractility or conduc-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does nicorandilare not exhibit effects on?. ### Response: contractility or conduc-tion.


Instruction: How many patients were enrolled in a prospective, randomized study of nitratemoiety?

Output: 5126

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in a prospective, randomized study of nitratemoiety?. ### Response: 5126.


Instruction: How many patients had chronic stable angina?

Output: 5126

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had chronic stable angina?. ### Response: 5126.


Instruction: What did the addition of nicorandil to standard therapy produce?

Output: 17%RR reduction in the composite endpoint of IHD death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the addition of nicorandil to standard therapy produce?. ### Response: 17%RR reduction in the composite endpoint of IHD death.


Instruction: How much reduction in the composite endpoint of IHD death?

Output: 17%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much reduction in the composite endpoint of IHD death?. ### Response: 17%.


Instruction: What type of pain did nicorandil and placebo cause?

Output: cardiacchest pain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of pain did nicorandil and placebo cause?. ### Response: cardiacchest pain.


Instruction: What was the difference between the two drugs?

Output: Ranolazine does not require dose adjustment for age, sex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between the two drugs?. ### Response: Ranolazine does not require dose adjustment for age, sex.


Instruction: What is limiting our ability to generalize our recommendations to many real-world patients?

Output: other comorbidities from enrollment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is limiting our ability to generalize our recommendations to many real-world patients?. ### Response: other comorbidities from enrollment.


Instruction: What must the clinician do as theyapply to a specific patient?

Output: using the best of the guideline recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must the clinician do as theyapply to a specific patient?. ### Response: using the best of the guideline recommendations.


Instruction: Future research will need to focus on what?

Output: novel pharmacolog-ical therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Future research will need to focus on what?. ### Response: novel pharmacolog-ical therapies.


Instruction: What is critical for patients hospitalized with HF?

Output: an evidence base

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is critical for patients hospitalized with HF?. ### Response: an evidence base.


Instruction: What are regenerative cell-based therapies to restore?

Output: myocardium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are regenerative cell-based therapies to restore?. ### Response: myocardium.


Instruction: CRT, ICD and left ventricular assist devices are examples of what?

Output: new device platforms that will either improve existing tech-nologies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CRT, ICD and left ventricular assist devices are examples of what?. ### Response: new device platforms that will either improve existing tech-nologies.


Instruction: What is critically needed?

Output: an evidence base

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is critically needed?. ### Response: an evidence base.


Instruction: What is critical needed is an evidence base that clearly identifies best processes ofcare?

Output: morbid devices that are capable ofchanging the natural history of HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is critical needed is an evidence base that clearly identifies best processes ofcare?. ### Response: morbid devices that are capable ofchanging the natural history of HF.


Instruction: What is an urgent need?

Output: preventing the burden of this disease through moresuccessful risk modi ﬁcation, sophisticated screening, perhapsusing speci ﬁc omics technologies (i.e., systems biology), oreffective treatment interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an urgent need?. ### Response: preventing the burden of this disease through moresuccessful risk modi ﬁcation, sophisticated screening, perhapsusing speci ﬁc omics technologies (i.e., systems biology), oreffective treatment interventions.


Instruction: Who is the President of the American College of Cardiology Foundation?

Output: Donna K. Arnett

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the President of the American College of Cardiology Foundation?. ### Response: Donna K. Arnett.


Instruction: Who is the Senior Vice President of Science and Quality?

Output: William J. Oetgen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Senior Vice President of Science and Quality?. ### Response: William J. Oetgen.


Instruction: What is the name of the senior director of science and clinical policy at the American College of Cardiology Foundation/American Heart Association?

Output: Charlene L. May

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the senior director of science and clinical policy at the American College of Cardiology Foundation/American Heart Association?. ### Response: Charlene L. May.


Instruction: Ramadhan III, Specialist, Science and Clinical PolicyWhat is Sarah Jackson, MPH?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ramadhan III, Specialist, Science and Clinical PolicyWhat is Sarah Jackson, MPH?. ### Response: American Heart Association.


Instruction: Who is the President of the American Heart Association?

Output: Nancy Brown

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the President of the American Heart Association?. ### Response: Nancy Brown.


Instruction: What is the Chief Executive Of ficer?

Output: Shalom Jacobovitz

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Chief Executive Of ficer?. ### Response: Shalom Jacobovitz.


Instruction: Who is the Senior VicePresident, Of fice of Science Operations?

Output: Gayle R. Whitman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Senior VicePresident, Of fice of Science Operations?. ### Response: Gayle R. Whitman.


Instruction: Who is production manager, Scientific Publications?

Output: Jody Hundley

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is production manager, Scientific Publications?. ### Response: Jody Hundley.


Instruction: What is the name of the Task Force on Practice Guidelines?

Output: F/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Practice Guidelines?. ### Response: F/AHA.


Instruction: What is the name of the committee that developed trustworthy clinical practice guidelines?

Output: Committee on Standards

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that developed trustworthy clinical practice guidelines?. ### Response: Committee on Standards.


Instruction: Where is the Committee on Standards for Systematic Reviews of ComparativeEffectiveness Research located?

Output: Washington, DC: TheNational Academies Press

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Committee on Standards for Systematic Reviews of ComparativeEffectiveness Research located?. ### Response: Washington, DC: TheNational Academies Press.


Instruction: What year did the Committee on Standards for Systematic Reviews of ComparativeEffectiveness Research publish Finding What Works inHealth Care?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Committee on Standards for Systematic Reviews of ComparativeEffectiveness Research publish Finding What Works inHealth Care?. ### Response: 2011.


Instruction: What is the name of the book published by the Institute of Medicine?

Output: Clinical Practice Guidelines We CanTrust

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book published by the Institute of Medicine?. ### Response: Clinical Practice Guidelines We CanTrust.


Instruction: What type of diet does CKD without diabetes have?

Output: low-protein versus normal-protein diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet does CKD without diabetes have?. ### Response: low-protein versus normal-protein diet.


Instruction: What is aerobic exercise to improve blood pressure versus control (no exercise/placebo?

Output: Adults with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aerobic exercise to improve blood pressure versus control (no exercise/placebo?. ### Response: Adults with CKD.


Instruction: What type of diet is recommended for adults with CKD without diabetes?

Output: low-protein versus normal-protein diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet is recommended for adults with CKD without diabetes?. ### Response: low-protein versus normal-protein diet.


Instruction: What is CR-LIPE?

Output: carbohydrate-restricted low-iron –available polyphenol-enriched

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CR-LIPE?. ### Response: carbohydrate-restricted low-iron –available polyphenol-enriched.


Instruction: Adults with diabetes and carbohydrate-restricted low-iron-available polyphenol-enriched diet versus usual diet?

Output: Table S53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults with diabetes and carbohydrate-restricted low-iron-available polyphenol-enriched diet versus usual diet?. ### Response: Table S53.


Instruction: What does CR-LIPE stand for?

Output: polyphenol-enriched

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CR-LIPE stand for?. ### Response: polyphenol-enriched.


Instruction: What is the standard protein –restricted diet?

Output: [0.8 g/kg/d],

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the standard protein –restricted diet?. ### Response: [0.8 g/kg/d],.


Instruction: How much isocaloric for ideal bodyweight maintenance?

Output: standard protein –restricted diet [0.8 g/kg/d],

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much isocaloric for ideal bodyweight maintenance?. ### Response: standard protein –restricted diet [0.8 g/kg/d],.


Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3757Kingdom and found to vary across what groups?

Output: groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3757Kingdom and found to vary across what groups?. ### Response: groups.


Instruction: The suitability of the scale to predict outcomes has not been fully established what?

Output: Meschia et al  Guidelines for the Primary Prevention of Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The suitability of the scale to predict outcomes has not been fully established what?. ### Response: Meschia et al  Guidelines for the Primary Prevention of Stroke.


Instruction: Alternative prediction models have been developed using other cohorts and what other set of risk factors?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Alternative prediction models have been developed using other cohorts and what other set of risk factors?. ### Response: stroke.


Instruction: What is one alternative stroke risk scoring system that omits cigarette smoking and antihypertensive medication?

Output: Alternative prediction models

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one alternative stroke risk scoring system that omits cigarette smoking and antihypertensive medication?. ### Response: Alternative prediction models.


Instruction: What is another alternative score derived from a mixed cohort of stroke and stroke-free patients?

Output: history of stroke, marital status, blood pressure (BP) as a categorical variable, high-den-sity lipoprotein (HDL) cholesterol, impaired expiratory flow, physical disability, and a depression score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another alternative score derived from a mixed cohort of stroke and stroke-free patients?. ### Response: history of stroke, marital status, blood pressure (BP) as a categorical variable, high-den-sity lipoprotein (HDL) cholesterol, impaired expiratory flow, physical disability, and a depression score.


Instruction: What is BP?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is BP?. ### Response: blood pressure.


Instruction: What is HDL cholesterol?

Output: high-den-sity lipoprotein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HDL cholesterol?. ### Response: high-den-sity lipoprotein.


Instruction: How many studies have generated risk assessment tools for patients with AF?

Output: Several

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have generated risk assessment tools for patients with AF?. ### Response: Several.


Instruction: What are risk assessment tools for use in patients with AF?

Output: Atrial Fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are risk assessment tools for use in patients with AF?. ### Response: Atrial Fibrillation.


Instruction: What has also been developed for other populations?

Output: Risk models

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has also been developed for other populations?. ### Response: Risk models.


Instruction: How was a stroke prediction model derived?

Output: age, sex, SBP, diastolic BP (DBP), family history of stroke, AF, and dia-betes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was a stroke prediction model derived?. ### Response: age, sex, SBP, diastolic BP (DBP), family history of stroke, AF, and dia-betes mellitus.


Instruction: What is BP also known as?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is BP also known as?. ### Response: blood pressure.


Instruction: What type of capacity does BP have?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of capacity does BP have?. ### Response: blood pressure.


Instruction: How has the DBP model been evaluated?

Output: diastolic BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How has the DBP model been evaluated?. ### Response: diastolic BP.


Instruction: The AHA/American Stroke Association emphasize the importance of including both stroke and coronary heart disease events as outcomes in what?

Output: risk prediction instruments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The AHA/American Stroke Association emphasize the importance of including both stroke and coronary heart disease events as outcomes in what?. ### Response: risk prediction instruments.


Instruction: What is available online for use in estimating risk at http://my.americanheart.org/?

Output: CV Risk Calculator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is available online for use in estimating risk at http://my.americanheart.org/?. ### Response: CV Risk Calculator.


Instruction: What type of tool does not exist that takes into account the effects of multiple risk factors?

Output: stroke risk assessment tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of tool does not exist that takes into account the effects of multiple risk factors?. ### Response: stroke risk assessment tool.


Instruction: What is the name of the tool that can be used to estimate stroke risk?

Output: CV Risk Calculator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the tool that can be used to estimate stroke risk?. ### Response: CV Risk Calculator.


Instruction: What are the newer risk factors for stroke?

Output: obstructive sleep apnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the newer risk factors for stroke?. ### Response: obstructive sleep apnea.


Instruction: What should be used with care because they do not include all the factors that contribute to disease risk?

Output: Risk assessment tools

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used with care because they do not include all the factors that contribute to disease risk?. ### Response: Risk assessment tools.


Instruction: What are the factors that contribute to disease risk?

Output: status, blood pressure (BP) as a categorical variable, high-den-sity lipoprotein (HDL) cholesterol, impaired expiratory flow, physical disability, and a depression score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the factors that contribute to disease risk?. ### Response: status, blood pressure (BP) as a categorical variable, high-den-sity lipoprotein (HDL) cholesterol, impaired expiratory flow, physical disability, and a depression score.


Instruction: What is the potential for harm from unnecessary application of interventions?

Output: inappropriate use of risk assessment tools or from the use of poorly adjudicated tools

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the potential for harm from unnecessary application of interventions?. ### Response: inappropriate use of risk assessment tools or from the use of poorly adjudicated tools.


Instruction: The utility of the FSP or other stroke risk assessment scales as a way of measuring stroke risk is what?

Output: not well studied

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The utility of the FSP or other stroke risk assessment scales as a way of measuring stroke risk is what?. ### Response: not well studied.


Instruction: What is not well studied?

Output: The utility of the FSP or other stroke risk assessment scales

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not well studied?. ### Response: The utility of the FSP or other stroke risk assessment scales.


Instruction: What is needed to validate risk assessment tools across age, sex, and race/ethnic groups?

Output: Research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to validate risk assessment tools across age, sex, and race/ethnic groups?. ### Response: Research.


Instruction: What adds to the predic-tive accuracy of existing scales?

Output: more recently identified risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What adds to the predic-tive accuracy of existing scales?. ### Response: more recently identified risk factors.


Instruction: What does the use of these scales improve?

Output: primary stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the use of these scales improve?. ### Response: primary stroke prevention.


Instruction: What should be considered in every patient?

Output: anatomic and physiological variables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered in every patient?. ### Response: anatomic and physiological variables.


Instruction: What should a patient be classified based on in Tables 3 and 4?

Output: the “highest” relevant anatomic or physiological feature

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient be classified based on in Tables 3 and 4?. ### Response: the “highest” relevant anatomic or physiological feature.


Instruction: What should a patient be classified based on?

Output: the “highest” relevant anatomic or physiological feature

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient be classified based on?. ### Response: the “highest” relevant anatomic or physiological feature.


Instruction: A normotensive patient with repaired CoA, normal exercise capacity, and normal end-organ function would be classified as what?

Output: ACHD AP classifi-cation IIA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A normotensive patient with repaired CoA, normal exercise capacity, and normal end-organ function would be classified as what?. ### Response: ACHD AP classifi-cation IIA.


Instruction: What is an otherwise similar patient with as-cending aortic diameter of 4.0 cm?

Output: ACHD AP classification IIB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an otherwise similar patient with as-cending aortic diameter of 4.0 cm?. ### Response: ACHD AP classification IIB.


Instruction: What would be the ACHD AP classification IIB with as-cending aortic diameter of 4.0 cm?

Output: patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be the ACHD AP classification IIB with as-cending aortic diameter of 4.0 cm?. ### Response: patient.


Instruction: What classification would be IIC if moderate stenosis were also present?

Output: ACHD AP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What classification would be IIC if moderate stenosis were also present?. ### Response: ACHD AP.


Instruction: Patients with ACHD may have what?

Output: baseline exercise limitations, cyanosis, end-organ dysfunction, or other clinically important comorbidities related to their CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with ACHD may have what?. ### Response: baseline exercise limitations, cyanosis, end-organ dysfunction, or other clinically important comorbidities related to their CHD.


Instruction: What are the clinically important comorbidities related to their CHD?

Output: baseline exercise limitations, cyanosis, end-organ dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinically important comorbidities related to their CHD?. ### Response: baseline exercise limitations, cyanosis, end-organ dysfunction.


Instruction: What are they at risk of?

Output: HF, arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are they at risk of?. ### Response: HF, arrhythmias.


Instruction: Dyspnea, chest pain, and exercise intolerance are examples of what?

Output: cardiac symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dyspnea, chest pain, and exercise intolerance are examples of what?. ### Response: cardiac symptoms.


Instruction: What may be present in patients with ACHD?

Output: baseline exercise limitations, cyanosis, end-organ dysfunction, or other clinically important comorbidities related to their CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be present in patients with ACHD?. ### Response: baseline exercise limitations, cyanosis, end-organ dysfunction, or other clinically important comorbidities related to their CHD.


Instruction: There are growing data regarding the prognostic implications of what?

Output: patients with ACHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are growing data regarding the prognostic implications of what?. ### Response: patients with ACHD.


Instruction: What is not the abun-dance of data available for patients with acquired heart disease?

Output: prognostic implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not the abun-dance of data available for patients with acquired heart disease?. ### Response: prognostic implications.


Instruction: Why were the data in Table 3 selected?

Output: data exist sug-gesting their importance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were the data in Table 3 selected?. ### Response: data exist sug-gesting their importance.


Instruction: What does QoL stand for?

Output: quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does QoL stand for?. ### Response: quality of life.


Instruction: As new data become availa-ble, what will happen to the relative weights attributable to the components of the ACHD AP classification?

Output: changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: As new data become availa-ble, what will happen to the relative weights attributable to the components of the ACHD AP classification?. ### Response: changes.


Instruction: What is similar to the New York Heart Association classification of functional status?

Output: ACHD AP classification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is similar to the New York Heart Association classification of functional status?. ### Response: ACHD AP classification.


Instruction: What may patients move from one ACHD AP classification to another over time?

Output: functional status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients move from one ACHD AP classification to another over time?. ### Response: functional status.


Instruction: What happens if clinical status worsens?

Output: the classification will change to a higher severity group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What happens if clinical status worsens?. ### Response: the classification will change to a higher severity group.


Instruction: What can result in a classification change to a lower severity group?

Output: improvement in status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can result in a classification change to a lower severity group?. ### Response: improvement in status.


Instruction: What is the AHA HF A to D classification?

Output: S2.3-17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHA HF A to D classification?. ### Response: S2.3-17.


Instruction: What classification is used throughout this document?

Output: ACHD AP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What classification is used throughout this document?. ### Response: ACHD AP.


Instruction: When considering follow-up visits and need for testing, what is used?

Output: ACHD AP classification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When considering follow-up visits and need for testing, what is used?. ### Response: ACHD AP classification.


Instruction: What changes in physiology can cause the ACHD AP classification to worsen?

Output: development of arrhyth-mias, HF, end-organ disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What changes in physiology can cause the ACHD AP classification to worsen?. ### Response: development of arrhyth-mias, HF, end-organ disease.


Instruction: What should be considered when considering follow-up visits and need for testing?

Output: ACHD AP classification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered when considering follow-up visits and need for testing?. ### Response: ACHD AP classification.


Instruction: What may not adequately discrimi-nate physiological changes that alter severity over time?

Output: anatomic disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not adequately discrimi-nate physiological changes that alter severity over time?. ### Response: anatomic disease.


Instruction: Exercise and heart failure:a statement from the American Heart Association Committee on exer-cise, rehabilitation, and prevention.

Output: Pina IL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise and heart failure:a statement from the American Heart Association Committee on exer-cise, rehabilitation, and prevention.. ### Response: Pina IL.


Instruction: Circulation 2003;107:1210–25.159.

Output: Pina IL, Apstein CS, Balady GJ, et al. Exercise and heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation 2003;107:1210–25.159.. ### Response: Pina IL, Apstein CS, Balady GJ, et al. Exercise and heart failure.


Instruction: What is a post hoc analysis of the Canadian Continuous PositiveAirway Pressure for Patients with Central Sleep Apnea and Heart FailureTrial (CANPAP)?

Output: Suppression of central sleep apneaby continuous positive airway pressure and transplant-free survival inheart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a post hoc analysis of the Canadian Continuous PositiveAirway Pressure for Patients with Central Sleep Apnea and Heart FailureTrial (CANPAP)?. ### Response: Suppression of central sleep apneaby continuous positive airway pressure and transplant-free survival inheart failure.


Instruction: Circulation 2007;115:3173 – what?

Output: 80.160

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation 2007;115:3173 – what?. ### Response: 80.160.


Instruction: What does continuous positive airwaypressure do for central sleep apnea and heart failure?

Output: Suppression of central sleep apneaby continuous positive airway pressure and transplant-free survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does continuous positive airwaypressure do for central sleep apnea and heart failure?. ### Response: Suppression of central sleep apneaby continuous positive airway pressure and transplant-free survival.


Instruction: What does Kaneko Y, Floras JS, Usui K, et al. do?

Output: Cardiovascular effects of continuouspositive airway pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Kaneko Y, Floras JS, Usui K, et al. do?. ### Response: Cardiovascular effects of continuouspositive airway pressure.


Instruction: What was the Engl J Med 2003:348:1233–41.162?

Output: Cardiovascular effects of continuouspositive airway pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Engl J Med 2003:348:1233–41.162?. ### Response: Cardiovascular effects of continuouspositive airway pressure.


Instruction: What did Mans field DR, Gollogly NC, Kaye DM, et al. do in obstructive sleep apnea and heartfailure?

Output: continuous positive airway pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Mans field DR, Gollogly NC, Kaye DM, et al. do in obstructive sleep apnea and heartfailure?. ### Response: continuous positive airway pressure.


Instruction: What is the name of the systematic review of factors that improve mortality and morbidity for patients with heart failure?

Output: Exercise training

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of factors that improve mortality and morbidity for patients with heart failure?. ### Response: Exercise training.


Instruction: What is Exercise training meta-analysis in patients with chronic heart failure called?

Output: ExTraMATCH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Exercise training meta-analysis in patients with chronic heart failure called?. ### Response: ExTraMATCH.


Instruction: What is the name of a randomized controlled trial of cardiac rehabilitation in elderly patients with heart failure?

Output: Eur J HeartFail

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a randomized controlled trial of cardiac rehabilitation in elderly patients with heart failure?. ### Response: Eur J HeartFail.


Instruction: What are the results of the five-year follow-up?

Output: ﬁndings froma randomized controlled trial of cardiac rehabilitation for heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the five-year follow-up?. ### Response: ﬁndings froma randomized controlled trial of cardiac rehabilitation for heart failure.


Instruction: What is enalapril compared with in the treatment of chronic congestiveheart failure?

Output: hydralazine-isosorbide dinitrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enalapril compared with in the treatment of chronic congestiveheart failure?. ### Response: hydralazine-isosorbide dinitrate.


Instruction: What is the name of the drug that is used to treat chronic heart failure in patients with reduced left ventricular ejection?

Output: enalapril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat chronic heart failure in patients with reduced left ventricular ejection?. ### Response: enalapril.


Instruction: What is the effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heartfailure?

Output: The SOLVD Investigators. Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heartfailure?. ### Response: The SOLVD Investigators. Effect.


Instruction: What was the N Engl J Med 1991:325:293–302.169?

Output: enalapril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med 1991:325:293–302.169?. ### Response: enalapril.


Instruction: How did the Collaborative Group on ACE Inhibitor Trials evaluate mortality and morbidity in heart failure patients?

Output: randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the Collaborative Group on ACE Inhibitor Trials evaluate mortality and morbidity in heart failure patients?. ### Response: randomized trials.


Instruction: What is the name of the group that studies ACE inhibitors?

Output: Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies ACE inhibitors?. ### Response: Collaborative Group.


Instruction: What is valsartan used for?

Output: chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is valsartan used for?. ### Response: chronic heart failure.


Instruction: When was the last issue of the ACCF/AHA Heart Failure Guidelines published?

Output: October 15, 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of the ACCF/AHA Heart Failure Guidelines published?. ### Response: October 15, 2013.


Instruction: When was the Executive Summary of the Guidelines released?

Output: October 15, 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Executive Summary of the Guidelines released?. ### Response: October 15, 2013.


Instruction: What was the name of the document that was released on October 15, 2013?

Output: ACCF/AHA Heart Failure Guidelines: Executive Summary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the document that was released on October 15, 2013?. ### Response: ACCF/AHA Heart Failure Guidelines: Executive Summary.


Instruction: What are writing committee members required to recuse themselves from voting on sections to which their specific relationships with industry mayapply?

Output: speciﬁ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are writing committee members required to recuse themselves from voting on sections to which their specific relationships with industry mayapply?. ### Response: speciﬁ.


Instruction: What indicates significant relationship?

Output: yIndicates signiﬁcant relationship.DSMB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates significant relationship?. ### Response: yIndicates signiﬁcant relationship.DSMB.


Instruction: What indicates Data Safety Monitoring Board?

Output: DSMB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates Data Safety Monitoring Board?. ### Response: DSMB.


Instruction: EP indicates electrophysiology.

Output: DSMB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: EP indicates electrophysiology.. ### Response: DSMB.


Instruction: What is PARADIGM?

Output: a Multicenter, Randomized, Double-blind, ParallelGroup, Active-controlled Study to Evaluate the Efﬁcacy and Safety of LCZ696

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PARADIGM?. ### Response: a Multicenter, Randomized, Double-blind, ParallelGroup, Active-controlled Study to Evaluate the Efﬁcacy and Safety of LCZ696.


Instruction: What is the name of the principal investigator of Enalapril?

Output: PI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the principal investigator of Enalapril?. ### Response: PI.


Instruction: What is UCLA's affiliation with the University of California, Los Angeles?

Output: SUNY, State University of New York

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is UCLA's affiliation with the University of California, Los Angeles?. ### Response: SUNY, State University of New York.


Instruction: What is the 2013 ACCF/AHA Heart Failure Guidelines: Executive Summary1535Downloaded From: http://content.onlinejacc.org/ on 04/17/2014

Output: JACC Vol. 62, No. 16, 2013 Yancy et al.October 15, 2013:1495 –539

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 ACCF/AHA Heart Failure Guidelines: Executive Summary1535Downloaded From: http://content.onlinejacc.org/ on 04/17/2014. ### Response: JACC Vol. 62, No. 16, 2013 Yancy et al.October 15, 2013:1495 –539.


Instruction: What is the name of the book that discusses the diagnosis of heart failure?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that discusses the diagnosis of heart failure?. ### Response: Chronic Heart Failure.


Instruction: What does NICE 2018 cover?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NICE 2018 cover?. ### Response: Chronic Heart Failure.


Instruction: Who is the author of Chronic Heart Failure?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Chronic Heart Failure?. ### Response: NICE 2018.


Instruction: What does NT-proBNP measure in people with suspected heart failure?

Output: N-terminal pro -B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NT-proBNP measure in people with suspected heart failure?. ### Response: N-terminal pro -B-type natriuretic peptide.


Instruction: What type of peptide carry a risk of heart failure in people?

Output: serum natriuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of peptide carry a risk of heart failure in people?. ### Response: serum natriuretic.


Instruction: What does high levels of NT-proBNP carry a poor prognosis?

Output: suspected heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does high levels of NT-proBNP carry a poor prognosis?. ### Response: suspected heart failure.


Instruction: Refer people with suspected heart failure to have specialist assessment and transthoracic echocardiography within how long?

Output: 6  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Refer people with suspected heart failure to have specialist assessment and transthoracic echocardiography within how long?. ### Response: 6  weeks.


Instruction: How long does it take for a person with suspected heart failure to have a specialist assessm ent and transthoracic echocardiography?

Output: 2 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a person with suspected heart failure to have a specialist assessm ent and transthoracic echocardiography?. ### Response: 2 weeks.


Instruction: What is the NT-proBNP level between 400 and 2,000 ng/litre?

Output: 47 to 236  pmol/litre) to have specialist assessm ent and transthoracic echocardiography within 6  weeks. [2018]   5. Be aware that:   an NT-proBNP  level less than 400  ng/litre (47 pmol/litre

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NT-proBNP level between 400 and 2,000 ng/litre?. ### Response: 47 to 236  pmol/litre) to have specialist assessm ent and transthoracic echocardiography within 6  weeks. [2018]   5. Be aware that:   an NT-proBNP  level less than 400  ng/litre (47 pmol/litre.


Instruction: What does NT-proBNP level in an untreated person make a diagnosis of heart failure less likely?

Output: less than 400  ng/litre

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NT-proBNP level in an untreated person make a diagnosis of heart failure less likely?. ### Response: less than 400  ng/litre.


Instruction: What does the level of serum natriuretic peptide do?

Output: can have causes other than heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the level of serum natriuretic peptide do?. ### Response: can have causes other than heart failure.


Instruction: What does not differentiate between heart failure with reduced ejection fraction and heart failur e with preserved eject frence?

Output: serum natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not differentiate between heart failure with reduced ejection fraction and heart failur e with preserved eject frence?. ### Response: serum natriuretic peptide.


Instruction: What does peptide not do?

Output: ifferentiate between heart failure with reduced ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does peptide not do?. ### Response: ifferentiate between heart failure with reduced ejection fraction.


Instruction: How do people with NT-proBNP levels below 400ng/litre experience heart failure?

Output: untreated person makes a diagnosis of heart failure less likely

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do people with NT-proBNP levels below 400ng/litre experience heart failure?. ### Response: untreated person makes a diagnosis of heart failure less likely.


Instruction: What is 400 ng/litre?

Output: 47 pmol/litre

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 400 ng/litre?. ### Response: 47 pmol/litre.


Instruction: What is the name of the subspecialty training in heart failure?

Output: NT-proBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the subspecialty training in heart failure?. ### Response: NT-proBNP.


Instruction: If there is concern that the symptoms might be related to heart failure, discuss with a physician what?

Output: w ith subspeciality training  in heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If there is concern that the symptoms might be related to heart failure, discuss with a physician what?. ### Response: w ith subspeciality training  in heart failure.


Instruction: What can reduce levels of serum natriuretic peptides?

Output: obesity, African or African -Caribbean family origin, or treatment with diuretics, angiotensin -converting enzyme (ACE)   inhibitors  , beta -blockers, angiotensin II receptor blockers  (ARBs) or mineralcorticoid receptor antagonist (MRA s)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can reduce levels of serum natriuretic peptides?. ### Response: obesity, African or African -Caribbean family origin, or treatment with diuretics, angiotensin -converting enzyme (ACE)   inhibitors  , beta -blockers, angiotensin II receptor blockers  (ARBs) or mineralcorticoid receptor antagonist (MRA s).


Instruction: What can have causes?

Output: high levels of serum natriuretic peptides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can have causes?. ### Response: high levels of serum natriuretic peptides.


Instruction: What can high levels of serum natriuretic peptides have other than heart failure?

Output: causes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can high levels of serum natriuretic peptides have other than heart failure?. ### Response: causes.


Instruction: How old is a person over 70 years?

Output: age over 70  years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is a person over 70 years?. ### Response: age over 70  years.


Instruction: What ischaemia?

Output: left ventricular hypertrophy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What ischaemia?. ### Response: left ventricular hypertrophy.


Instruction: What does tran sthoracic echocardiography exclude?

Output: important valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does tran sthoracic echocardiography exclude?. ### Response: important valve disease.


Instruction: What is performed to assess the systolic function of the (left) ventricle and detect intracardiac shunts?

Output: tran sthoracic echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed to assess the systolic function of the (left) ventricle and detect intracardiac shunts?. ### Response: tran sthoracic echocardiography.


Instruction: What should be performed on high-resolution equipment?

Output: Transthoracic echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed on high-resolution equipment?. ### Response: Transthoracic echocardiography.


Instruction: What should not compromise quality?

Output: Need and demand for these studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not compromise quality?. ### Response: Need and demand for these studies.


Instruction: What year was the rule changed?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the rule changed?. ### Response: 2010.


Instruction: What year did the rule change?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the rule change?. ### Response: 2010.


Instruction: What is a predictor of mortality associated with malignant ventricular arrhythmias in non-ST elevation myocardial infarction patients?

Output: Incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of mortality associated with malignant ventricular arrhythmias in non-ST elevation myocardial infarction patients?. ### Response: Incidence.


Instruction: What does Hjalmarson A say about beta blockade?

Output: Effects of beta blockade on sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Hjalmarson A say about beta blockade?. ### Response: Effects of beta blockade on sudden cardiac death.


Instruction: What is the term for acute myocardial infarction and the postinfarction period?

Output: sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for acute myocardial infarction and the postinfarction period?. ### Response: sudden cardiac death.


Instruction: When did Katritsis DG, Zareba W, Camm AJ, write a paper on nonsustained ventricular tachycar -dia?

Output: 2012;60:1993–2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Katritsis DG, Zareba W, Camm AJ, write a paper on nonsustained ventricular tachycar -dia?. ### Response: 2012;60:1993–2004.


Instruction: What was the name of the study in Hamburg on implantable cardioverter defibrillator compared with antiarrhythmic drug treatment?

Output: Cardiac Arrest Study Hamburg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study in Hamburg on implantable cardioverter defibrillator compared with antiarrhythmic drug treatment?. ### Response: Cardiac Arrest Study Hamburg.


Instruction: What did the Cardiac Arrest Study Hamburg do?

Output: Implantable cardioverter defibrillator compared with antiarrhythmic drug treatment in cardiac arrest survivors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Cardiac Arrest Study Hamburg do?. ### Response: Implantable cardioverter defibrillator compared with antiarrhythmic drug treatment in cardiac arrest survivors.


Instruction: What was the name of the study?

Output: Cardiac Arrest Study Hamburg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: Cardiac Arrest Study Hamburg.


Instruction: How many people died from cardiac arrest in 1994?

Output: 579

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people died from cardiac arrest in 1994?. ### Response: 579.


Instruction: What is the name of the Canadian implantable Defibrillator study?

Output: Cardiac Arrest Study Hamburg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Canadian implantable Defibrillator study?. ### Response: Cardiac Arrest Study Hamburg.


Instruction: When was the Eur Heart J.21:2071–8 published?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur Heart J.21:2071–8 published?. ### Response: 2000.


Instruction: Where did NICE add a cr oss-r eference t o related NICE medical technologies guidance?

Output: at t he end of section 1 .3.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did NICE add a cr oss-r eference t o related NICE medical technologies guidance?. ### Response: at t he end of section 1 .3.4.


Instruction: What is the ISBN number for Accreditation Recent onset chest pain of suspect ed car diac origin?

Output: 9 78-1-47 31-2182-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ISBN number for Accreditation Recent onset chest pain of suspect ed car diac origin?. ### Response: 9 78-1-47 31-2182-9.


Instruction: Assessment and diagnosis (CG95) NICE 2022.

Output: All right s reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Assessment and diagnosis (CG95) NICE 2022.. ### Response: All right s reserved.