Instruction: What was the protocol outcome in NYHA class?

Output: improvement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the protocol outcome in NYHA class?. ### Response: improvement.


Instruction: How was QoL measured?

Output: EQ-5D, EQ -5D VAS and KCCQ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was QoL measured?. ### Response: EQ-5D, EQ -5D VAS and KCCQ.


Instruction: What did CABG and PCI show?

Output: clinically important benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did CABG and PCI show?. ### Response: clinically important benefit.


Instruction: What did the outcomes QoL and stroke show no clinically important effect of?

Output: C ABG (plus medical management).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the outcomes QoL and stroke show no clinically important effect of?. ### Response: C ABG (plus medical management)..


Instruction: At what time did all-cause mortality show a clinically significant harm of CABG?

Output: 30 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what time did all-cause mortality show a clinically significant harm of CABG?. ### Response: 30 days.


Instruction: What is CABG plus medical management?

Output: with medical management alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CABG plus medical management?. ### Response: with medical management alone.


Instruction: What was the extended follow up period of 9.8 years?

Output: evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the extended follow up period of 9.8 years?. ### Response: evidence.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett et al.


Instruction: What is the name of the guideline published by the American College of Cardiology?

Output: Guideline on the Primary Prevention of Cardiovascular DiseaseCirculation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline published by the American College of Cardiology?. ### Response: Guideline on the Primary Prevention of Cardiovascular DiseaseCirculation.


Instruction: When was the last date of publication for the ACC and AHA guideline?

Output: September 10, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last date of publication for the ACC and AHA guideline?. ### Response: September 10, 2019.


Instruction: What is a community guide systematic review of?

Output: Team-based care and improved blood pressure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a community guide systematic review of?. ### Response: Team-based care and improved blood pressure control.


Instruction: What is the name of the systematic review that focuses on pharmacist-physician medication-therapy management?

Output: community guide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review that focuses on pharmacist-physician medication-therapy management?. ### Response: community guide.


Instruction: What is a primary care-based, pharmacist-physician collaborative medication-therapy management of?

Output: hyper -tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a primary care-based, pharmacist-physician collaborative medication-therapy management of?. ### Response: hyper -tension.


Instruction: What is the name of the randomized controlled trial of team-based care?

Output: S2.1-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial of team-based care?. ### Response: S2.1-9.


Instruction: When was the J Gen Intern Med published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Gen Intern Med published?. ### Response: 2011.


Instruction: What is the name of the study that evaluated pharmacists' work in a physician-pharmacist collaborative model for the manage-ment of hypertension?

Output: Pharmacotherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated pharmacists' work in a physician-pharmacist collaborative model for the manage-ment of hypertension?. ### Response: Pharmacotherapy.


Instruction: What year did Pharmacotherapy issue 36:374–84?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Pharmacotherapy issue 36:374–84?. ### Response: 2016.


Instruction: What does SCRIP-HTN stand for?

Output: pharmacists-hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SCRIP-HTN stand for?. ### Response: pharmacists-hypertension.


Instruction: What is the name of the study of cardiovascular risk intervention by pharmacists-hypertension?

Output: SCRIP-HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study of cardiovascular risk intervention by pharmacists-hypertension?. ### Response: SCRIP-HTN.


Instruction: What is the cost-effectiveness of a physi-cian-pharmacist collaboration intervention to improve?

Output: blood pres-sure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of a physi-cian-pharmacist collaboration intervention to improve?. ### Response: blood pres-sure control.


Instruction: Hypertension. 2015;66:1145–51.

Output: S2.1-12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertension. 2015;66:1145–51.. ### Response: S2.1-12.


Instruction: What model is used to improve chronic care in an academic primary care practice?

Output: Teamlet Model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What model is used to improve chronic care in an academic primary care practice?. ### Response: Teamlet Model.


Instruction: What is the name of the Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus?

Output: RAMP-DM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus?. ### Response: RAMP-DM.


Instruction: What is RAMP-DM?

Output: Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is RAMP-DM?. ### Response: Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus.


Instruction: What is the acronym for Management Programme-Diabetes Mellitus?

Output: RAMP-DM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Management Programme-Diabetes Mellitus?. ### Response: RAMP-DM.


Instruction: What does RAMP-DM stand for?

Output: Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does RAMP-DM stand for?. ### Response: Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus.


Instruction: How many people were enrolled in the 2018 Diabetes Care study?

Output: 41:49–59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the 2018 Diabetes Care study?. ### Response: 41:49–59.


Instruction: Informed shared decision-mak-ing on the prevention of myocardial infarction in type 2 diabetes: a randomised controlled trial?

Output: Buhse S

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Informed shared decision-mak-ing on the prevention of myocardial infarction in type 2 diabetes: a randomised controlled trial?. ### Response: Buhse S.


Instruction: What type of diabetes: a randomised controlled trial?

Output: type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes: a randomised controlled trial?. ### Response: type 2 diabetes.


Instruction: What is the name of the randomized controlled trial to improve patient-centered care in underserved pri-mary care patients?

Output: Cooper LA, Roter DL, Carson KA, et al. A randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial to improve patient-centered care in underserved pri-mary care patients?. ### Response: Cooper LA, Roter DL, Carson KA, et al. A randomized trial.


Instruction: What does Office-GAP stand for?

Output: Office-Guidelines Applied to Practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Office-GAP stand for?. ### Response: Office-Guidelines Applied to Practice.


Instruction: What is the name of the quasi-experimental design study used to implement shared deci-sion making?

Output: Office-Guidelines Applied to Practice (Office-GAP) program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the quasi-experimental design study used to implement shared deci-sion making?. ### Response: Office-Guidelines Applied to Practice (Office-GAP) program.


Instruction: What is the 2018 ACHD Guideline?

Output: Stout et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 ACHD Guideline?. ### Response: Stout et al.


Instruction: What should be evaluated for adults presenting with cor triatriatum sinister?

Output: pulmonary vein stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be evaluated for adults presenting with cor triatriatum sinister?. ### Response: pulmonary vein stenosis.


Instruction: Where are studies that support recommendations summarized?

Output: Online Data Supplement 31

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are studies that support recommendations summarized?. ### Response: Online Data Supplement 31.


Instruction: ASD, VSD, and anomalous pulmonary venous connection should be evaluated for what?

Output: congenital abnormalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ASD, VSD, and anomalous pulmonary venous connection should be evaluated for what?. ### Response: congenital abnormalities.


Instruction: In adults with prior repair of cor triatriatum sinister and recurrent symptoms, it is reasonable to evaluate for pulmonary vein stenosis.

Output: S4.2.1-1IIa B-NR2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adults with prior repair of cor triatriatum sinister and recurrent symptoms, it is reasonable to evaluate for pulmonary vein stenosis.. ### Response: S4.2.1-1IIa B-NR2.


Instruction: What is indicated when undergoing surgical repair?

Output: symptoms attributable to the obstruction or a substantial gradient across the membrane

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated when undergoing surgical repair?. ### Response: symptoms attributable to the obstruction or a substantial gradient across the membrane.


Instruction: What is surgical repair indicated for adults with cor triatriatum sinister?

Output: symptoms attributable to the obstruction or a substantial gradient across the membrane

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is surgical repair indicated for adults with cor triatriatum sinister?. ### Response: symptoms attributable to the obstruction or a substantial gradient across the membrane.


Instruction: What occurs when a membrane divides either the left atrium (sinister) or right atrium?

Output: Cor triatriatum

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What occurs when a membrane divides either the left atrium (sinister) or right atrium?. ### Response: Cor triatriatum.


Instruction: What is Cor tria-triatum sinister associated with?

Output: congen-ital malformations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Cor tria-triatum sinister associated with?. ### Response: congen-ital malformations.


Instruction: ASD, VSD, or anomalous pulmonary venous connection are examples of what?

Output: congen-ital malformations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ASD, VSD, or anomalous pulmonary venous connection are examples of what?. ### Response: congen-ital malformations.


Instruction: The left atrial appendage is invariably in the same chamber as what valve?

Output: mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The left atrial appendage is invariably in the same chamber as what valve?. ### Response: mitral valve.


Instruction: What separated the pulmo-nary veins by the membrane?

Output: The left atrial appendage is invariably in the same chamber as the mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What separated the pulmo-nary veins by the membrane?. ### Response: The left atrial appendage is invariably in the same chamber as the mitral valve.


Instruction: What separates the mitral valve from the pulmo-nary veins?

Output: the membrane

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What separates the mitral valve from the pulmo-nary veins?. ### Response: the membrane.


Instruction: What causes supravalvular mitral steno-sis?

Output: a fibrous ring on the atrial side of the mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes supravalvular mitral steno-sis?. ### Response: a fibrous ring on the atrial side of the mitral valve.


Instruction: A fibrous ring is located on the atrial side of what?

Output: mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A fibrous ring is located on the atrial side of what?. ### Response: mitral valve.


Instruction: What type of valve can be associated with supravalvular mitral stenosis?

Output: abnormal mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve can be associated with supravalvular mitral stenosis?. ### Response: abnormal mitral valve.


Instruction: What is a common cause of supravavular withral stenose?

Output: a fibrous ring on the atrial side of the mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of supravavular withral stenose?. ### Response: a fibrous ring on the atrial side of the mitral valve.


Instruction: What is a sequence of serial left-sided inflow and outflow obstructions called?

Output: Shone complex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a sequence of serial left-sided inflow and outflow obstructions called?. ### Response: Shone complex.


Instruction: What section of the Shone complex provides recommendations on who should perform surgeries, cardiac catheterization, and other procedures?

Output: Supportive Text

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section of the Shone complex provides recommendations on who should perform surgeries, cardiac catheterization, and other procedures?. ### Response: Supportive Text.


Instruction: What is triatriatum sinister?

Output: a membrane spanning the left atrium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is triatriatum sinister?. ### Response: a membrane spanning the left atrium.


Instruction: What is a membrane spanning the left atrium?

Output: Cor triatriatum sinister

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a membrane spanning the left atrium?. ### Response: Cor triatriatum sinister.


Instruction: Surgery has been largely success-ful with how many early or late deaths?

Output: relatively few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Surgery has been largely success-ful with how many early or late deaths?. ### Response: relatively few.


Instruction: The gradient across the de-fect at the time of surgery was at least what?

Output: 8 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The gradient across the de-fect at the time of surgery was at least what?. ### Response: 8 mm Hg.


Instruction: What is the average pulmonary vein stenosis?

Output: 17 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average pulmonary vein stenosis?. ### Response: 17 mm Hg.


Instruction: What is not ex-pected after repair?

Output: recurrence of stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not ex-pected after repair?. ### Response: recurrence of stenosis.


Instruction: How long has pulmonary stenosis been demonstrated before and after surgery?

Output: prior repair of cor triatriatum sinister and recurrent symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has pulmonary stenosis been demonstrated before and after surgery?. ### Response: prior repair of cor triatriatum sinister and recurrent symptoms.


Instruction: What has been demon-strated before and after surgery?

Output: Pulmonary venous stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been demon-strated before and after surgery?. ### Response: Pulmonary venous stenosis.


Instruction: Pulmonary venous stenosis has not been associated with what?

Output: PAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pulmonary venous stenosis has not been associated with what?. ### Response: PAH.


Instruction: What is e7364.2.3?

Output: Subaortic Stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is e7364.2.3?. ### Response: Subaortic Stenosis.


Instruction: What is Turner Syndrome?

Output: Congenital Valvular Aortic Stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Turner Syndrome?. ### Response: Congenital Valvular Aortic Stenosis.


Instruction: Coarctation of the Aorta......... e7414.3. Right-Sided Lesions............

Output: e7404.2.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Coarctation of the Aorta......... e7414.3. Right-Sided Lesions............. ### Response: e7404.2.6.


Instruction: e7434.3.1. Valvular Pulmonary Stenosis?

Output: Isolated PR After Repair of PS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: e7434.3.1. Valvular Pulmonary Stenosis?. ### Response: Isolated PR After Repair of PS.


Instruction: What is Isolated PR After Repair of PS?

Output: e7454.3.2. Branch and Peripheral Pulmonary  Stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Isolated PR After Repair of PS?. ### Response: e7454.3.2. Branch and Peripheral Pulmonary  Stenosis.


Instruction: Branch and Peripheral Pulmonar Stenosi........................................................ e7524.4 What is Double-Chambered Right Ventricle?

Output: Right Ventricle to Pulmonary  Artery Conduit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Branch and Peripheral Pulmonar Stenosi........................................................ e7524.4 What is Double-Chambered Right Ventricle?. ### Response: Right Ventricle to Pulmonary  Artery Conduit.


Instruction: What is a Ventricle to Pulmonary Artery Conduit?

Output: Right

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Ventricle to Pulmonary Artery Conduit?. ### Response: Right.


Instruction: What are Complex Lesions?

Output: Transposition of the Great Arteries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Complex Lesions?. ### Response: Transposition of the Great Arteries.


Instruction: Transposition of the Great Arteries With Atrial Switch?

Output: e75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Transposition of the Great Arteries With Atrial Switch?. ### Response: e75.


Instruction: Arteries With Arterial Switch e7564.4.1.3 What type of repair does Rastelli Type Repair do?

Output: Transposition of the Great  Arteries With Rastelli Type  Repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arteries With Arterial Switch e7564.4.1.3 What type of repair does Rastelli Type Repair do?. ### Response: Transposition of the Great  Arteries With Rastelli Type  Repair.


Instruction: What is a congenitally corrected transposition of the great arteries?

Output: Atrial Switch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a congenitally corrected transposition of the great arteries?. ### Response: Atrial Switch.


Instruction: e7584.4.2. Fontan Palliation of Single Ventricle Physiology includes Tricuspid Atresia and what other physiology?

Output: Double Inlet Left Ventricle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: e7584.4.2. Fontan Palliation of Single Ventricle Physiology includes Tricuspid Atresia and what other physiology?. ### Response: Double Inlet Left Ventricle.


Instruction: What is Hypoplastic Left Heart?

Output: Syndrome/Norwood Repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Hypoplastic Left Heart?. ### Response: Syndrome/Norwood Repair.


Instruction: Hypoplastic Left Heart Syndrome/Norwood Repair..........e7634.4.4. Truncus Arteriosus.......................e7634.4.6.1. Severe PAH and Eisenmenger Syndrome?

Output: e7634.4.6. Severe PAH and Eisenmenger  Syndrome ....................... e7634.4.6.1.  Severe PAH ........

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypoplastic Left Heart Syndrome/Norwood Repair..........e7634.4.4. Truncus Arteriosus.......................e7634.4.6.1. Severe PAH and Eisenmenger Syndrome?. ### Response: e7634.4.6. Severe PAH and Eisenmenger  Syndrome ....................... e7634.4.6.1.  Severe PAH .........


Instruction: Eisenmenge Syndrome.............................. e7654.4.7.1. What type of Artery is anomalous?

Output: Coronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Eisenmenge Syndrome.............................. e7654.4.7.1. What type of Artery is anomalous?. ### Response: Coronary.


Instruction: e7654.4.7. Coronary Anomalies............... e7474.4.7 What is anomalous Coronary Artery Evaluation?

Output: Anomalous Coronary Artery Evaluation . . . . . . . . . . . . . . . . e7684.4.7.2.  Anomalous Aortic Origin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: e7654.4.7. Coronary Anomalies............... e7474.4.7 What is anomalous Coronary Artery Evaluation?. ### Response: Anomalous Coronary Artery Evaluation . . . . . . . . . . . . . . . . e7684.4.7.2.  Anomalous Aortic Origin.


Instruction: What is aortic origin of Coronary artery?

Output: Anomalous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aortic origin of Coronary artery?. ### Response: Anomalous.


Instruction: e7694.4.7.3 Anomalous Coronary Artery Arising From the PA?

Output: Anomalous Aortic Origin  of Coronary Artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: e7694.4.7.3 Anomalous Coronary Artery Arising From the PA?. ### Response: Anomalous Aortic Origin  of Coronary Artery.


Instruction: Evidence Gaps and Future Directions............................................................

Output: e7705

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence Gaps and Future Directions............................................................. ### Response: e7705.


Instruction: How many Author Relationships with Industry and Other Entities are there?

Output: 773

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Author Relationships with Industry and Other Entities are there?. ### Response: 773.


Instruction: What is the name of the Appendix 2 of the AHA Journals?

Output: Reviewer Relationships With Industry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Appendix 2 of the AHA Journals?. ### Response: Reviewer Relationships With Industry.


Instruction: When was the Aha Journals first downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Aha Journals first downloaded?. ### Response: April 28, 2023.


Instruction: Where was the ahajournals first download?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the ahajournals first download?. ### Response: http://ahajournals.org.


Instruction: What is the name of the journal that was downloaded from http://ahajournals.org by on May 1, 2023?

Output: ahajournals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that was downloaded from http://ahajournals.org by on May 1, 2023?. ### Response: ahajournals.


Instruction: Why did no deaths occur during the 30-day follow-up period in either group?

Output: low certainty evidence).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did no deaths occur during the 30-day follow-up period in either group?. ### Response: low certainty evidence)..


Instruction: Bridging with what may reduce the risk for any recurrent VTE?

Output: LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bridging with what may reduce the risk for any recurrent VTE?. ### Response: LMWH.


Instruction: What includes both important benefit and important harm?

Output: burden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What includes both important benefit and important harm?. ### Response: burden.


Instruction: Why do very few events occur for patients at the time of CI?

Output: low to moderate risk for recurrent VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do very few events occur for patients at the time of CI?. ### Response: low to moderate risk for recurrent VTE.


Instruction: How many events occur for patients at low to moderate risk for recurrent VTE?

Output: very few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many events occur for patients at low to moderate risk for recurrent VTE?. ### Response: very few.


Instruction: Why is the absolute effect of the VTE very small?

Output: very few eventsoccur for patients at low to moderate risk for recurrent VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the absolute effect of the VTE very small?. ### Response: very few eventsoccur for patients at low to moderate risk for recurrent VTE.


Instruction: What is the RR of the recurrence of VTE upgraded to?

Output: 0.34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the RR of the recurrence of VTE upgraded to?. ### Response: 0.34.


Instruction: What was the risk of clinically relevant bleeding among those receiving bridging with LMWH compared with those who interrupted warfarin therapy alone?

Output: increased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of clinically relevant bleeding among those receiving bridging with LMWH compared with those who interrupted warfarin therapy alone?. ### Response: increased.


Instruction: What was associated with lower patientsatisfaction?

Output: Bridging with LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with lower patientsatisfaction?. ### Response: Bridging with LMWH.


Instruction: What increased the risk of delay in intervention?

Output: Bridging with LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increased the risk of delay in intervention?. ### Response: Bridging with LMWH.


Instruction: What did the composite of prolonged hospitalization and hematoma require?

Output: interruption of anticoagulation or evacuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the composite of prolonged hospitalization and hematoma require?. ### Response: interruption of anticoagulation or evacuation.


Instruction: How many more delayed interventions per 1000?

Output: 125

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many more delayed interventions per 1000?. ### Response: 125.


Instruction: What are some EtD criteria and considerations associated with LMWH bridging?

Output: resourcerequirements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some EtD criteria and considerations associated with LMWH bridging?. ### Response: resourcerequirements.


Instruction: What is likely to be large driven by the cost, complexity of teaching patients theintervention, and management of bleeding events?

Output: resourcerequirements associated with LMWH bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to be large driven by the cost, complexity of teaching patients theintervention, and management of bleeding events?. ### Response: resourcerequirements associated with LMWH bridging.


Instruction: What was a much highervalue placed on the risk for bleeding?

Output: LMWH bridging in available studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a much highervalue placed on the risk for bleeding?. ### Response: LMWH bridging in available studies.


Instruction: What has been consistently associated with LMWH bridging in available studies?

Output: the risk for bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been consistently associated with LMWH bridging in available studies?. ### Response: the risk for bleeding.


Instruction: The panel was confident that the desirable effects of what were desirable?

Output: mechanical heart valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The panel was confident that the desirable effects of what were desirable?. ### Response: mechanical heart valves.


Instruction: What did the panel feel was outweighed by the undesirable effects of LMWH bridging?

Output: desirable effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the panel feel was outweighed by the undesirable effects of LMWH bridging?. ### Response: desirable effects.


Instruction: What does not apply to patients requiring VKA therapy for indications in addition toVTE?

Output: LMWH bridging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not apply to patients requiring VKA therapy for indications in addition toVTE?. ### Response: LMWH bridging.


Instruction: What type of valves were identified as a research priority by the panel?

Output: mechanical heart valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valves were identified as a research priority by the panel?. ### Response: mechanical heart valves.


Instruction: What was the primary focus of the panel's study?

Output: sufficiently powered RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary focus of the panel's study?. ### Response: sufficiently powered RCTs.


Instruction: What should laboratory testing for DOACanticoagulant effect be used vs?

Output: interrupting DOAC therapy alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should laboratory testing for DOACanticoagulant effect be used vs?. ### Response: interrupting DOAC therapy alone.


Instruction: What does the ASH guideline panel suggest against for patients interrupting DOAC therapy?

Output: per-forming laboratory testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ASH guideline panel suggest against for patients interrupting DOAC therapy?. ### Response: per-forming laboratory testing.


Instruction: What is a rationale for optimizing surgical indications?

Output: regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a rationale for optimizing surgical indications?. ### Response: regurgitation.


Instruction: When did Circulation. 1999:400-5?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 1999:400-5?. ### Response: 1999.


Instruction: What should patients with severe degenerative mitral regurgitation delay surgery until symptoms develop?

Output: watchful waiting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with severe degenerative mitral regurgitation delay surgery until symptoms develop?. ### Response: watchful waiting.


Instruction: What is the outcome of watchful waiting in as-ymptomatic severe mitral regurgitation?

Output: Outcome of watchful waiting in as-ymptomatic severe mitral regurgitation. Circulation. 2006;113:2238–44

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the outcome of watchful waiting in as-ymptomatic severe mitral regurgitation?. ### Response: Outcome of watchful waiting in as-ymptomatic severe mitral regurgitation. Circulation. 2006;113:2238–44.


Instruction: What was the Circulation. 2006;113:2238-44?

Output: Outcome of watchful waiting in as-ymptomatic severe mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Circulation. 2006;113:2238-44?. ### Response: Outcome of watchful waiting in as-ymptomatic severe mitral regurgitation.


Instruction: How did Kang D-H, Kim JH, Rim JH compare early surgery versus conventional treatment?

Output: Comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Kang D-H, Kim JH, Rim JH compare early surgery versus conventional treatment?. ### Response: Comparison.


Instruction: What is the temporal response of left ven-tricular performance to mitral valve surgery?

Output: 5. Schuler G, Peterson KL, Johnson A, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the temporal response of left ven-tricular performance to mitral valve surgery?. ### Response: 5. Schuler G, Peterson KL, Johnson A, et al.


Instruction: What is Echocardiographic predic-tion of survival after surgical correction of organic mitral regurgitation?

Output: 830–7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Echocardiographic predic-tion of survival after surgical correction of organic mitral regurgitation?. ### Response: 830–7.


Instruction: What is the survival implication of left ven-tricular end-systolic diameter in mitral regurgitation due to flail leaflets?

Output: early surgical intervention vs watchful waiting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the survival implication of left ven-tricular end-systolic diameter in mitral regurgitation due to flail leaflets?. ### Response: early surgical intervention vs watchful waiting.


Instruction: What is a long-term follow-up multicenter study?

Output: Survival implication of left ven-tricular end-systolic diameter in mitral regurgitation due to flail leaflets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a long-term follow-up multicenter study?. ### Response: Survival implication of left ven-tricular end-systolic diameter in mitral regurgitation due to flail leaflets.


Instruction: What are the determinants of the outcome of asymptomatic mitral regurgitation?

Output: watchful waiting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the determinants of the outcome of asymptomatic mitral regurgitation?. ### Response: watchful waiting.


Instruction: What is Crawford MH, Souchek J, Oprian CA, et al. Determinants of survival after mitral valve replacement.

Output: left ventricular performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Crawford MH, Souchek J, Oprian CA, et al. Determinants of survival after mitral valve replacement.. ### Response: left ventricular performance.


Instruction: What is a predictor of postoperative left ventricular performance in volume overload from valvu-lar regurgitation?

Output: End-systolic volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of postoperative left ventricular performance in volume overload from valvu-lar regurgitation?. ### Response: End-systolic volume.


Instruction: What is the name of the study on Valvular Heart Disease. Circulation. 1990;81:1173–81.

Output: Department of Veterans Affairs Cooperative Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study on Valvular Heart Disease. Circulation. 1990;81:1173–81.. ### Response: Department of Veterans Affairs Cooperative Study.


Instruction: What is the effect of recurrent mitral regurgitation following degenerative mitral valve repair?

Output: long-term analysis of competing outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of recurrent mitral regurgitation following degenerative mitral valve repair?. ### Response: long-term analysis of competing outcomes.


Instruction: What was the J Am Coll Cardiol 201667:488–98?

Output: Effect of recurrent mitral regurgi-tation following degenerative mitral valve repair: long-term analysis of competing outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol 201667:488–98?. ### Response: Effect of recurrent mitral regurgi-tation following degenerative mitral valve repair: long-term analysis of competing outcomes.


Instruction: How did Vassileva CM, Mishkel G, McNeely C, et al. compare Medicare fee-for-service?

Output: longitudinal analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Vassileva CM, Mishkel G, McNeely C, et al. compare Medicare fee-for-service?. ### Response: longitudinal analysis.


Instruction: What is a longitudinal analysis of Medicare fee-for-service beneficiaries?

Output: Long-term survival of patients undergoing mitral valve repair and replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a longitudinal analysis of Medicare fee-for-service beneficiaries?. ### Response: Long-term survival of patients undergoing mitral valve repair and replacement.


Instruction: What is an association between early surgical intervention vs watchful waiting and outcomes for mitral regurgitation?

Output: flail mitral valve leaflets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an association between early surgical intervention vs watchful waiting and outcomes for mitral regurgitation?. ### Response: flail mitral valve leaflets.


Instruction: What is the name of the multicenter European study on mitral regurgita-tion due to flail leaflets?

Output: JACC Cardiovasc Imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter European study on mitral regurgita-tion due to flail leaflets?. ### Response: JACC Cardiovasc Imaging.


Instruction: How long does it take for mitral repair versus replacement to be successful?

Output: Twenty-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for mitral repair versus replacement to be successful?. ### Response: Twenty-year.


Instruction: What type of repair versus replacement for severe degenerative mitral regur?

Output: mitral repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of repair versus replacement for severe degenerative mitral regur?. ### Response: mitral repair.


Instruction: What is the purpose of this study?

Output: long-term follow-up multicenter study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of this study?. ### Response: long-term follow-up multicenter study.


Instruction: How is left ventricular function predicted?

Output: End-systolic volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is left ventricular function predicted?. ### Response: End-systolic volume.


Instruction: What is a class III recommendation to delineate if the recommendation is determined to be of “no benefit” or is associated with “harm” to the patient?

Output: recommenda-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class III recommendation to delineate if the recommendation is determined to be of “no benefit” or is associated with “harm” to the patient?. ### Response: recommenda-tion.


Instruction: What is an increasing number of comparative effectiveness studies?

Output: comparatorverbs and suggested phrases for writing recommendations forthe comparative effectiveness of one treatment or strategyversus another have been added for COR I and IIa, LOE A orB only

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increasing number of comparative effectiveness studies?. ### Response: comparatorverbs and suggested phrases for writing recommendations forthe comparative effectiveness of one treatment or strategyversus another have been added for COR I and IIa, LOE A orB only.


Instruction: What has been added for COR I and IIa, LOE A orB?

Output: comparatorverbs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been added for COR I and IIa, LOE A orB?. ### Response: comparatorverbs.


Instruction: What has the Task Forcedesignated to represent optimal medical therapy?

Output: guideline-directed medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has the Task Forcedesignated to represent optimal medical therapy?. ### Response: guideline-directed medical therapy.


Instruction: What does GDMT stand for?

Output: guideline-directed medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GDMT stand for?. ### Response: guideline-directed medical therapy.


Instruction: What is the primary class of recommended therapies in the ACCF/AHA guideline?

Output: Class I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary class of recommended therapies in the ACCF/AHA guideline?. ### Response: Class I.


Instruction: What is discussed in the text without a specific COR?

Output: drugs that are not currently available in NorthAmerica

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is discussed in the text without a specific COR?. ### Response: drugs that are not currently available in NorthAmerica.


Instruction: What does each writing committee review for studies performed in large numbers of subjects outside of North America?

Output: the potential influ-ence of different practice patterns and patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does each writing committee review for studies performed in large numbers of subjects outside of North America?. ### Response: the potential influ-ence of different practice patterns and patient.


Instruction: What is the purpose of the ACCF/AHA practice guidelines?

Output: to assisthealthcare providers in clinical decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of the ACCF/AHA practice guidelines?. ### Response: to assisthealthcare providers in clinical decision making.


Instruction: What are the guidelines intended to assist in?

Output: clinical decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the guidelines intended to assist in?. ### Response: clinical decision making.


Instruction: What do the guidelines attempt to define?

Output: practices thatmeet the needs of most patients in most circumstances

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the guidelines attempt to define?. ### Response: practices thatmeet the needs of most patients in most circumstances.


Instruction: What must be made by the healthcare provider and patient in light of all the circumstances presented by that patient?

Output: Theultimate judgment regarding care of a particular patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be made by the healthcare provider and patient in light of all the circumstances presented by that patient?. ### Response: Theultimate judgment regarding care of a particular patient.


Instruction: What should clinical decision making include?

Output: consideration of the quality and availability of exper-tise in the area where care is provided

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should clinical decision making include?. ### Response: consideration of the quality and availability of exper-tise in the area where care is provided.


Instruction: What should be considered in the area where care is provided?

Output: quality and availability of exper-tise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered in the area where care is provided?. ### Response: quality and availability of exper-tise.


Instruction: How are guidelines used in regulatory decisions?

Output: as the basis for regulatory or payer decisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are guidelines used in regulatory decisions?. ### Response: as the basis for regulatory or payer decisions.


Instruction: What should the goal be when guidelines are used as the basis for regulatory or payer decisions?

Output: improvement in quality of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the goal be when guidelines are used as the basis for regulatory or payer decisions?. ### Response: improvement in quality of care.


Instruction: What does the TaskForce recognize that situations arise in which additional data is needed to inform patient care more effectively?

Output: comparative effectiveness studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the TaskForce recognize that situations arise in which additional data is needed to inform patient care more effectively?. ### Response: comparative effectiveness studies.


Instruction: What should be identified within each respective guideline whenappropriate?

Output: additional dataare needed to inform patient care more effectively

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be identified within each respective guideline whenappropriate?. ### Response: additional dataare needed to inform patient care more effectively.


Instruction: What is effective only if prescribed courses of treatment are followed?

Output: Prescribed courses of treatment in accordance with theserecommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective only if prescribed courses of treatment are followed?. ### Response: Prescribed courses of treatment in accordance with theserecommendations.


Instruction: What do patients with higher predischarge levels and patients who do not have a decrease in natriuretic peptide biomarker levels during hospitalization have worse outcomes?

Output: worse outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients with higher predischarge levels and patients who do not have a decrease in natriuretic peptide biomarker levels during hospitalization have worse outcomes?. ### Response: worse outcomes.


Instruction: What did natriuretic peptide biomarker reduction have better outcomes than?

Output: those without any changes or with a biomarker rise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did natriuretic peptide biomarker reduction have better outcomes than?. ### Response: those without any changes or with a biomarker rise.


Instruction: Targeting a certain threshold, value or relative change in these biomarkers during hospitalization may not be practical or safe for every patient?

Output: has not been tested in a prospective large-scale trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Targeting a certain threshold, value or relative change in these biomarkers during hospitalization may not be practical or safe for every patient?. ### Response: has not been tested in a prospective large-scale trial.


Instruction: What should be the focus of clinical assessment and adherence to GDMT?

Output: prognostic value of a predischarge value or relative changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the focus of clinical assessment and adherence to GDMT?. ### Response: prognostic value of a predischarge value or relative changes.


Instruction: The prognostic value of a predischarge value or relative changes does not imply the necessity for what during hospitalization?

Output: serial and repeated biomarker measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The prognostic value of a predischarge value or relative changes does not imply the necessity for what during hospitalization?. ### Response: serial and repeated biomarker measurements.


Instruction: What may be considered for additive risk stratification in patients with chronic HF?

Output: measurement of other clinically available tests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for additive risk stratification in patients with chronic HF?. ### Response: measurement of other clinically available tests.


Instruction: What has been combined into prognosis section?

Output: 2013 recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been combined into prognosis section?. ### Response: 2013 recommendations.


Instruction: What is predictive of hospitalization and death in patients with HF?

Output: Biomarkers of myocardial fibrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is predictive of hospitalization and death in patients with HF?. ### Response: Biomarkers of myocardial fibrosis.


Instruction: What is additive to natriuretic peptide biomarker levels in their prognostic value?

Output: Biomarkers of myocardial fibrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is additive to natriuretic peptide biomarker levels in their prognostic value?. ### Response: Biomarkers of myocardial fibrosis.


Instruction: What may ultimately prove to be more informative than single biomarkers?

Output: A combination of biomarkers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may ultimately prove to be more informative than single biomarkers?. ### Response: A combination of biomarkers.


Instruction: Where can you find a copy of the ahajournals.org recomendations?

Output: http://ahajournals.org by on May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find a copy of the ahajournals.org recomendations?. ### Response: http://ahajournals.org by on May 3, 2023.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the DOI: 10.1161/CIR.0000000000000923 February 2, 2021 e221?

Output: CLINICAL STATEMENTS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI: 10.1161/CIR.0000000000000923 February 2, 2021 e221?. ### Response: CLINICAL STATEMENTS.


Instruction: What is the purpose of defining the intrinsic cardiac risks of opera-tions?

Output: to improve preoperative cardiac risk assessments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of defining the intrinsic cardiac risks of opera-tions?. ### Response: to improve preoperative cardiac risk assessments.


Instruction: What are the results of this study?

Output: 1-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of this study?. ### Response: 1-year.


Instruction: How is functional capacity assessed before surgery?

Output: an international, prospective cohort study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is functional capacity assessed before surgery?. ### Response: an international, prospective cohort study.


Instruction: What is a new index for pre-operative cardiovascular evaluation?

Output: ACC/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new index for pre-operative cardiovascular evaluation?. ### Response: ACC/AHA.


Instruction: What is the 2014 AHA/ACC guideline for the management of patients with valvular heart disease?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 AHA/ACC guideline for the management of patients with valvular heart disease?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?

Output: line on perioperative cardiovascular evaluation and management of pa-tients undergoing noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines do?. ### Response: line on perioperative cardiovascular evaluation and management of pa-tients undergoing noncardiac surgery.


Instruction: What is the name of the group that did a report on the management of patients with valvular heart disease?

Output: American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that did a report on the management of patients with valvular heart disease?. ### Response: American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: When was the ACCF/ASE/AHA/ASNC/HFSA/HRS/SCCM/SCCT/SCMR 2011?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ACCF/ASE/AHA/ASNC/HFSA/HRS/SCCM/SCCT/SCMR 2011?. ### Response: 2011.


Instruction: What is an echocar-diography?

Output: American Society of Echocardiog-raphy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an echocar-diography?. ### Response: American Society of Echocardiog-raphy.


Instruction: What is the American College of Cardiology Foundation Appropriate Use Criteria Task Force?

Output: A report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the American College of Cardiology Foundation Appropriate Use Criteria Task Force?. ### Response: A report.


Instruction: What is the Society for Cardiovascular Magnetic Resonance?

Output: So-ciety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Society for Cardiovascular Magnetic Resonance?. ### Response: So-ciety.


Instruction: What is a 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients?

Output: valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients?. ### Response: valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What does the American College of Cardiology/American Heart Association Task Force on Practice Guidelines focus on?

Output: perioperative cardiovascular evaluation and management of pa-tients undergoing noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American College of Cardiology/American Heart Association Task Force on Practice Guidelines focus on?. ### Response: perioperative cardiovascular evaluation and management of pa-tients undergoing noncardiac surgery.


Instruction: What is the name of the group that compiled a report on the management of patients with valvular heart disease?

Output: American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that compiled a report on the management of patients with valvular heart disease?. ### Response: American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: When was the Circulation.129:e521–643?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.129:e521–643?. ### Response: 2014.


Instruction: How is the aortic-valve replaced?

Output: self-expanding prosthesis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the aortic-valve replaced?. ### Response: self-expanding prosthesis.


Instruction: What is the name of the prosthesis that is self-expanding?

Output: Transcatheter aortic-valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prosthesis that is self-expanding?. ### Response: Transcatheter aortic-valve replacement.


Instruction: What year did N Engl J Med publish 370:1790–8?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med publish 370:1790–8?. ### Response: 2014.


Instruction: How long did it take to achieve 2-Year outcomes in patients undergoing aortic valve replacement?

Output: 2015;66:113–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to achieve 2-Year outcomes in patients undergoing aortic valve replacement?. ### Response: 2015;66:113–.


Instruction: Transcatheter versus surgical aortic valve replacement: 1-year results from the all-comers NOTION randomized clinical trial?

Output: Thyregod HGH, Steinbrüchel DA, Ihlemann N, et al. Transcatheter versus surgical aortic valve replacement in patients with severe aortic valve ste-nosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Transcatheter versus surgical aortic valve replacement: 1-year results from the all-comers NOTION randomized clinical trial?. ### Response: Thyregod HGH, Steinbrüchel DA, Ihlemann N, et al. Transcatheter versus surgical aortic valve replacement in patients with severe aortic valve ste-nosis.


Instruction: J Am Coll Cardiol 2015;65:2184–94.

Output: Transcatheter versus surgical aortic valve replacement in patients with severe aortic valve ste-nosis: 1-year results from the all-comers NOTION randomized clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Am Coll Cardiol 2015;65:2184–94.. ### Response: Transcatheter versus surgical aortic valve replacement in patients with severe aortic valve ste-nosis: 1-year results from the all-comers NOTION randomized clinical trial.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 54 of 127 mortality?

Output: federal recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 54 of 127 mortality?. ### Response: federal recommendations.


Instruction: What was associated with a 20% reduction in CV and all-cause mortality compared to no leisure time activity?

Output: Leisure time activity levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a 20% reduction in CV and all-cause mortality compared to no leisure time activity?. ### Response: Leisure time activity levels.


Instruction: What percentage reduction in all-cause mortality was associated with activity three to five times the recommended level?

Output: 39%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage reduction in all-cause mortality was associated with activity three to five times the recommended level?. ### Response: 39%.


Instruction: What was the reduction in CV mortality associated with?

Output: light leisure time physical activ ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in CV mortality associated with?. ### Response: light leisure time physical activ ity.


Instruction: How many times the recommendation level was related to activity 3 to 5 times?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times the recommendation level was related to activity 3 to 5 times?. ### Response: three.


Instruction: The dose -response curve demonstrated an upper limit of benefit at what time?

Output: three to five times recommended levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The dose -response curve demonstrated an upper limit of benefit at what time?. ### Response: three to five times recommended levels.


Instruction: What is the upper limit of benefit at three to five times recommended levels?

Output: dose -response curve demonstrated an upper limit of benefit at three to five times recommended levels, suggesting a ceiling effect on leisure time physical activity benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the upper limit of benefit at three to five times recommended levels?. ### Response: dose -response curve demonstrated an upper limit of benefit at three to five times recommended levels, suggesting a ceiling effect on leisure time physical activity benefits.


Instruction: Evidence indicates a benefit to activity levels much lower than what?

Output: federal recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence indicates a benefit to activity levels much lower than what?. ### Response: federal recommendations.


Instruction: What did Chastin et al. 2017 show?

Output: 29% reduction in all- cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Chastin et al. 2017 show?. ### Response: 29% reduction in all- cause mortality.


Instruction: What was the reduction in all cause mortality in primary prevention patients?

Output: 29%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in all cause mortality in primary prevention patients?. ### Response: 29%.


Instruction: How much time was reduced by LIPA?

Output: 2 – 4 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much time was reduced by LIPA?. ### Response: 2 – 4 hours.


Instruction: What are METs?

Output: metabolic equivalent of task

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are METs?. ### Response: metabolic equivalent of task.


Instruction: How much faster is a MET than a treadmill?

Output: 2 mph

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much faster is a MET than a treadmill?. ### Response: 2 mph.


Instruction: In what study did Schnohr and colleagues follow 12,000 primary prevention patients?

Output: Copenhagen City Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what study did Schnohr and colleagues follow 12,000 primary prevention patients?. ### Response: Copenhagen City Heart Study.


Instruction: How many primary prevention patients were studied for over 30 years?

Output: over 12,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many primary prevention patients were studied for over 30 years?. ### Response: over 12,000.


Instruction: What was the reduction in CV mortality found in patients persistently at light leisure time physical activity?

Output: 24%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in CV mortality found in patients persistently at light leisure time physical activity?. ### Response: 24%.


Instruction: How many hours LIPA per week were found in persistently sedentary patients?

Output: (<2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours LIPA per week were found in persistently sedentary patients?. ### Response: (<2.


Instruction: How many times a week did LIPA occur?

Output: 2 – 4 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times a week did LIPA occur?. ### Response: 2 – 4 hours.


Instruction: What did the Work Group not report about safety?

Output: outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group not report about safety?. ### Response: outcomes.


Instruction: What did the Work Group recognize musculoskeletal injuries are not uncommon during exercise?

Output: Safety outcomes were not reported

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group recognize musculoskeletal injuries are not uncommon during exercise?. ### Response: Safety outcomes were not reported.


Instruction: The Work Group determined the available body of evidence ha d significant what?

Output: methodologic limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Work Group determined the available body of evidence ha d significant what?. ### Response: methodologic limitations.


Instruction: What was not reported?

Output: Safety outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not reported?. ### Response: Safety outcomes.


Instruction: What could have impacted outcomes in large prospective cohorts?

Output: imbalance in unmeasured CV prognostic variables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could have impacted outcomes in large prospective cohorts?. ### Response: imbalance in unmeasured CV prognostic variables.


Instruction: What type of bias did many studies utilize?

Output: self- reported physical activity levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of bias did many studies utilize?. ### Response: self- reported physical activity levels.


Instruction: What is the body of evidence on the CVD benefits of exercise?

Output: a positive association of high magnitude

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the body of evidence on the CVD benefits of exercise?. ### Response: a positive association of high magnitude.


Instruction: What was consistently demonstrated across large studies?

Output: positive association of high magnitude

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was consistently demonstrated across large studies?. ### Response: positive association of high magnitude.


Instruction: Positive effects were found on important patient outcomes in a dose-response relationship?

Output: any movement in daily living during their leisure time might have beneficial effects on CV and all- cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Positive effects were found on important patient outcomes in a dose-response relationship?. ### Response: any movement in daily living during their leisure time might have beneficial effects on CV and all- cause mortality.


Instruction: What cant determinant of whether the DBP is a major risk predictor?

Output: cant determinant of whether the DBP is a major risk predictor. Therefore, in those studies that reported a J curve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What cant determinant of whether the DBP is a major risk predictor?. ### Response: cant determinant of whether the DBP is a major risk predictor. Therefore, in those studies that reported a J curve.


Instruction: What are possible explanations for diminished myocardial perfusion during diastole?

Output: an age-related increase in pulse pressure reflecting stiffer large arteries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are possible explanations for diminished myocardial perfusion during diastole?. ### Response: an age-related increase in pulse pressure reflecting stiffer large arteries.


Instruction: What type of epiphenomenon is related to a known or undetected underlying illness?

Output: cancer, HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of epiphenomenon is related to a known or undetected underlying illness?. ### Response: cancer, HF.


Instruction: What is reverse causality?

Output: the pre-existing illness explains both the low BP and the high risk of death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reverse causality?. ### Response: the pre-existing illness explains both the low BP and the high risk of death.


Instruction: How many 1991 patients participated in the CAMELOT trial?

Output: 150

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many 1991 patients participated in the CAMELOT trial?. ### Response: 150.


Instruction: How many patients had angiographically documented CAD in the CAMELOT trial in 1991?

Output: 150

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had angiographically documented CAD in the CAMELOT trial in 1991?. ### Response: 150.


Instruction: What was the mean entry BP?

Output: 129/77 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean entry BP?. ### Response: 129/77 mm Hg.


Instruction: How much did treatment with an ACE inhibi-tor or a CCB lowered BP by?

Output: 5/2 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did treatment with an ACE inhibi-tor or a CCB lowered BP by?. ### Response: 5/2 mm Hg.


Instruction: What percentage of white adults with diabetes mellitus have coronary heart disease?

Output: ≈45%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of white adults with diabetes mellitus have coronary heart disease?. ### Response: ≈45%.


Instruction: What type of trials have not shown a J curve?

Output: Clinical Trials to Specifically Evaluate Lower  BP GoalsData from controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of trials have not shown a J curve?. ### Response: Clinical Trials to Specifically Evaluate Lower  BP GoalsData from controlled trials.


Instruction: What percent of white adults with diabetes mellitus have coronary heart disease?

Output: ≈45%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percent of white adults with diabetes mellitus have coronary heart disease?. ### Response: ≈45%.


Instruction: What percentage of non-diabetic individuals have CAD?

Output: 25%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of non-diabetic individuals have CAD?. ### Response: 25%.


Instruction: The ACCORD study is relevant to the issue of what?

Output: BP targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ACCORD study is relevant to the issue of what?. ### Response: BP targets.


Instruction: What did the BP study20 randomized 4733 patients to?

Output: an intensive therapy arm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the BP study20 randomized 4733 patients to?. ### Response: an intensive therapy arm.


Instruction: How many patients had had a previous cardiovascular event?

Output: 34%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had had a previous cardiovascular event?. ### Response: 34%.


Instruction: What was the SBP target?

Output: <120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the SBP target?. ### Response: <120 mm Hg.


Instruction: What was the mean SBP in the intensive therapy group after 1 year?

Output: 119.3 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean SBP in the intensive therapy group after 1 year?. ### Response: 119.3 mm Hg.


Instruction: How was the SBP target in the standard therapy group?

Output: 133.5 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the SBP target in the standard therapy group?. ### Response: 133.5 mm Hg.


Instruction: After 1 year, what was the average SBP?

Output: 119.3 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After 1 year, what was the average SBP?. ### Response: 119.3 mm Hg.


Instruction: How many mm Hg difference was there in the standard therapy group?

Output: 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mm Hg difference was there in the standard therapy group?. ### Response: 14.


Instruction: What was the mean follow-up of the study?

Output: 4.7 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean follow-up of the study?. ### Response: 4.7 years.


Instruction: How long did the study last?

Output: 4.7 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: 4.7 years.


Instruction: Why was there no difference between the 2 groups?

Output: primary composite outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there no difference between the 2 groups?. ### Response: primary composite outcome.


Instruction: What is another term for nonfatal stroke?

Output: death resulting from cardiovascular causes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for nonfatal stroke?. ### Response: death resulting from cardiovascular causes.


Instruction: What is a term for all-cause mortality?

Output: nonfa-tal MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for all-cause mortality?. ### Response: nonfa-tal MI.


Instruction: How much lower was the risk of the primary composite end point in those randomized to the lower goal?

Output: 12%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much lower was the risk of the primary composite end point in those randomized to the lower goal?. ### Response: 12%).


Instruction: What was the risk of MI in the group randomized to the lower BP target?

Output: lower (by 13%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of MI in the group randomized to the lower BP target?. ### Response: lower (by 13%).


Instruction: What was not statistically significant?

Output: the risk of MI was lower (by 13%) in the group randomized to the lower BP target

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not statistically significant?. ### Response: the risk of MI was lower (by 13%) in the group randomized to the lower BP target.


Instruction: In the intensive therapy group, what was the putatively significantly lower incidence of stroke?

Output: uncorrected for multiple comparisons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the intensive therapy group, what was the putatively significantly lower incidence of stroke?. ### Response: uncorrected for multiple comparisons.


Instruction: How many strokes were there in the intensive therapy group?

Output: 98

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in the intensive therapy group?. ### Response: 98.


Instruction: What was the number of strokes?

Output: 98

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the number of strokes?. ### Response: 98.


Instruction: Who concluded that an SBP 120 mm Hg in type 2 dia-betes mellitus is not justified?

Output: investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who concluded that an SBP 120 mm Hg in type 2 dia-betes mellitus is not justified?. ### Response: investigators.


Instruction: What is the name of the 2011 ACCF/AHA expert consensus document on hypertension in the elderly?

Output: S9.2.2-16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2011 ACCF/AHA expert consensus document on hypertension in the elderly?. ### Response: S9.2.2-16.


Instruction: What was developed in collaboration with the American Academy of Neurology, American Geriatrics Society and American Society for Aging?

Output: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed in collaboration with the American Academy of Neurology, American Geriatrics Society and American Society for Aging?. ### Response: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents.


Instruction: What is the American Academy of Neurology?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the American Academy of Neurology?. ### Response: JAMA.


Instruction: What are the American Society for Preventive Cardiology, American Society of Nephrology, and European Society of Hypertension?

Output: Association of Black Cardiologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the American Society for Preventive Cardiology, American Society of Nephrology, and European Society of Hypertension?. ### Response: Association of Black Cardiologists.


Instruction: When was Circulation. 2011;123:2434–506.

Output: S9.2.2-17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation. 2011;123:2434–506.. ### Response: S9.2.2-17.


Instruction: What is prevention of heart failure?

Output: antihypertensive drug treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is prevention of heart failure?. ### Response: antihypertensive drug treatment.


Instruction: What does antihypertensive drug treatment prevent?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does antihypertensive drug treatment prevent?. ### Response: heart failure.


Instruction: What is the name of the group that studies the prevention of heart failure in older people?

Output: SHEP Cooperative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies the prevention of heart failure in older people?. ### Response: SHEP Cooperative Research Group.


Instruction: When was the JAMA published?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 2013.


Instruction: How old were the patients treated for hypertension?

Output: 80 years of age or older

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old were the patients treated for hypertension?. ### Response: 80 years of age or older.


Instruction: What year did N Engl J Med publish 358:1887-98?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med publish 358:1887-98?. ### Response: 2008.


Instruction: What is the name of the antihypertensive and lipid-lowering treatment to prevent heart attack trial?

Output: ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the antihypertensive and lipid-lowering treatment to prevent heart attack trial?. ### Response: ALLHAT.


Instruction: When was the ALHAT trial conducted?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ALHAT trial conducted?. ### Response: 2011.


Instruction: What is the effect of inhibition of phosphodies-terase-5 on exercise capacity and clinical status?

Output: heart failure with preserved ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of inhibition of phosphodies-terase-5 on exercise capacity and clinical status?. ### Response: heart failure with preserved ejection fraction.


Instruction: What is a potential benefit of inhibition?

Output: exercise capacity and clinical status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential benefit of inhibition?. ### Response: exercise capacity and clinical status.


Instruction: How does heart failure compare to antihy-pertensive?

Output: pre-served and reduced left ventricular ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does heart failure compare to antihy-pertensive?. ### Response: pre-served and reduced left ventricular ejection fraction.


Instruction: What is the effect of phosphodies-terase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction?

Output: a randomized clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of phosphodies-terase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction?. ### Response: a randomized clinical trial.


Instruction: What journal published a randomized clinical trial in 2013?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What journal published a randomized clinical trial in 2013?. ### Response: JAMA.


Instruction: How does dietary protein restriction and blood pressure control affect the progression of chronic renal disease?

Output: The effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does dietary protein restriction and blood pressure control affect the progression of chronic renal disease?. ### Response: The effects.


Instruction: What is the effect of blood-pressure control on the progression of chronic renal disease?

Output: dietary protein restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of blood-pressure control on the progression of chronic renal disease?. ### Response: dietary protein restriction.


Instruction: What was the name of the multicentre, randomised controlled trial of blood pressure control for renoprotection in non-diabetic chronic renal disease?

Output: REIN-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the multicentre, randomised controlled trial of blood pressure control for renoprotection in non-diabetic chronic renal disease?. ### Response: REIN-2.


Instruction: What is chronic renal dis-ease?

Output: REIN-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is chronic renal dis-ease?. ### Response: REIN-2.


Instruction: What is the name of the multicentre, randomised controlled trial?

Output: Blood-pressure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicentre, randomised controlled trial?. ### Response: Blood-pressure control.


Instruction: When did the AASK trial begin?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the AASK trial begin?. ### Response: 2002.


Instruction: What is a blood pressure target in chronic kidney disease and proteinuria as an effect modifier?

Output: Systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a blood pressure target in chronic kidney disease and proteinuria as an effect modifier?. ### Response: Systematic review.


Instruction: When was the Ann Intern Med published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Intern Med published?. ### Response: 2011.