Instruction: What was the risk difference with No ElasticCompression Stockings?

Output: Anticipated Absolute Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk difference with No ElasticCompression Stockings?. ### Response: Anticipated Absolute Effects.


Instruction: What is the risk difference with ElasticCompression Stockings (95% CI)?

Output: relative effect of the intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk difference with ElasticCompression Stockings (95% CI)?. ### Response: relative effect of the intervention.


Instruction: Why is the mean acute legPain742(1 study)60 d4442Moderatee,hbecause ofimprecision?

Output: mean acute leg painin the control groupswas 1.13 leg painseverity assessedon an 11-pointnumerical painrating scalei

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the mean acute legPain742(1 study)60 d4442Moderatee,hbecause ofimprecision?. ### Response: mean acute leg painin the control groupswas 1.13 leg painseverity assessedon an 11-pointnumerical painrating scalei.


Instruction: How much higher was the mean acute leg pain in the intervention groups?

Output: 0.26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was the mean acute leg pain in the intervention groups?. ### Response: 0.26.


Instruction: What is the mean QoL in theintervention group?

Output: 0.12 lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mean QoL in theintervention group?. ### Response: 0.12 lower.


Instruction: What was the median control group risk across studies?

Output: assumed risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median control group risk across studies?. ### Response: assumed risk.


Instruction: What is the basis for the assumed risk in the comparison group and the relative effect of the study?

Output: the median control group risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the basis for the assumed risk in the comparison group and the relative effect of the study?. ### Response: the median control group risk.


Instruction: What is the 95% CI for the relative effect of the intervention?

Output: Anticipated Absolute EffectsRisk with No ElasticCompression StockingsRisk Difference with ElasticCompression Stockings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% CI for the relative effect of the intervention?. ### Response: Anticipated Absolute EffectsRisk with No ElasticCompression StockingsRisk Difference with ElasticCompression Stockings.


Instruction: What is SF-3614Short Form 36?

Output: ECS ¼elastic compression stockings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SF-3614Short Form 36?. ### Response: ECS ¼elastic compression stockings.


Instruction: How many studies were originally included for this outcome?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were originally included for this outcome?. ### Response: 3.


Instruction: What was very high heterogeneity?

Output: There were 3 studies originally included for this outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was very high heterogeneity?. ### Response: There were 3 studies originally included for this outcome.


Instruction: S12.4.1-5. Bardach NS, Wang JJ, De Leon SF, et al. Effect of pay-for-per-formance incentives on quality of care in small practices with electronic health records: a randomized trial?

Output: JAMA. 2013;310:1051–9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: S12.4.1-5. Bardach NS, Wang JJ, De Leon SF, et al. Effect of pay-for-per-formance incentives on quality of care in small practices with electronic health records: a randomized trial?. ### Response: JAMA. 2013;310:1051–9.


Instruction: What is the name of the organization that developed the ACCF/AHA/AMA-PCPI 2011 performance measures for adults with coronary artery disease and hypertension?

Output: American College of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that developed the ACCF/AHA/AMA-PCPI 2011 performance measures for adults with coronary artery disease and hypertension?. ### Response: American College of Cardiology Foundation.


Instruction: What did the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures and the American Medical Association-Physician Consortium for Performance Improvement do?

Output: performance measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures and the American Medical Association-Physician Consortium for Performance Improvement do?. ### Response: performance measures.


Instruction: When did Circulation. 2011;124:248–70.

Output: 1483

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2011;124:248–70.. ### Response: 1483.


Instruction: What did Powers BJ, Olsen MK, Smith V A, et al. measure for decision making and quality reporting?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Powers BJ, Olsen MK, Smith V A, et al. measure for decision making and quality reporting?. ### Response: blood pressure.


Instruction: How many measures are there for pressure for decision making and quality reporting?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many measures are there for pressure for decision making and quality reporting?. ### Response: blood pressure.


Instruction: When was the Ann Intern Med 154:781–8; W-289–90?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Intern Med 154:781–8; W-289–90?. ### Response: 2011.


Instruction: What is the ACCF/AHA method-ology for?

Output: development of quality measures for cardiovascu-lar technology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACCF/AHA method-ology for?. ### Response: development of quality measures for cardiovascu-lar technology.


Instruction: What is the acronym for the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures?

Output: ACCF/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures?. ### Response: ACCF/AHA.


Instruction: When was the Circulation.124:1483–502.12.4.2 released?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.124:1483–502.12.4.2 released?. ### Response: 2011.


Instruction: What was the name of the systematic review of quality improve-ment strategies for hypertension management?

Output: community guide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic review of quality improve-ment strategies for hypertension management?. ### Response: community guide.


Instruction: What did Carter BL, Rogers M, Daly J, et al. study?

Output: The potency of team-based care interventions for hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Carter BL, Rogers M, Daly J, et al. study?. ### Response: The potency of team-based care interventions for hypertension.


Instruction: What did Glynn LG, Murphy AW, Smith SM, and SmithSM use to improve control of blood pressure in patients with hypertension?

Output: Interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Glynn LG, Murphy AW, Smith SM, and SmithSM use to improve control of blood pressure in patients with hypertension?. ### Response: Interventions.


Instruction: What does DSS stand for?

Output: Decision Support System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does DSS stand for?. ### Response: Decision Support System.


Instruction: What is the name of the systematic review of team-based care and improved blood pressure control?

Output: a community guide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of team-based care and improved blood pressure control?. ### Response: a community guide.


Instruction: What is the role of Decision Support System in prevention of cardiovascular disease?

Output: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of Decision Support System in prevention of cardiovascular disease?. ### Response: a systematic review and meta-analysis.


Instruction: What is a community-based, multifaceted intervention to improve blood pressure control called?

Output: Check it, change it

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a community-based, multifaceted intervention to improve blood pressure control called?. ### Response: Check it, change it.


Instruction: What is the purpose of this study?

Output: randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of this study?. ### Response: randomized trial.


Instruction: What is a large-scale hypertension program associated with?

Output: Improved blood pressure con-trol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a large-scale hypertension program associated with?. ### Response: Improved blood pressure con-trol.


Instruction: When will this study be available?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will this study be available?. ### Response: May 3, 2023.


Instruction: What is the name of the study that examined body mass index, waist circumference, and risk of coronary heart disease among men and women?

Output: prospective study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined body mass index, waist circumference, and risk of coronary heart disease among men and women?. ### Response: prospective study.


Instruction: What does the American Heart Association say about extreme obesity and what you can do?

Output: https://www.heart.org/en/healthy-living/healthy-eating/losing-weight/extreme-obesity-and-what-you-can-do. Accessed January 5, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American Heart Association say about extreme obesity and what you can do?. ### Response: https://www.heart.org/en/healthy-living/healthy-eating/losing-weight/extreme-obesity-and-what-you-can-do. Accessed January 5, 2019.


Instruction: What is the name of the organization that studies obesity?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that studies obesity?. ### Response: American Heart Association.


Instruction: Where can you find more information about obesity and what you can do?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find more information about obesity and what you can do?. ### Response: American Heart Association.


Instruction: When was the prevalence of obesity among adults and youth in the United States?

Output: 2015–2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the prevalence of obesity among adults and youth in the United States?. ### Response: 2015–2016.


Instruction: Asad Z, Abbas M, Javed I, et al. Obesity is associated with incident atrial fibrillation independent of what?

Output: gender

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Asad Z, Abbas M, Javed I, et al. Obesity is associated with incident atrial fibrillation independent of what?. ### Response: gender.


Instruction: J Cardiovasc Electrophysiol. 2018;29:725–32.

Output: 145–54

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Cardiovasc Electrophysiol. 2018;29:725–32.. ### Response: 145–54.


Instruction: What is the 2013 AHA/ACC/TOS guideline for the management of?

Output: overweight and obesity in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 AHA/ACC/TOS guideline for the management of?. ### Response: overweight and obesity in adults.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society do?

Output: a report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society do?. ### Response: a report.


Instruction: What is the name of the group that did a report on the management of overweight and obesity in adults?

Output: ive Services Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that did a report on the management of overweight and obesity in adults?. ### Response: ive Services Task Force.


Instruction: Who wrote a systematic and clinical review of long-term drug treatment for obesity?

Output: Yanovski SZ, Yanovski JA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote a systematic and clinical review of long-term drug treatment for obesity?. ### Response: Yanovski SZ, Yanovski JA.


Instruction: What is the name of the systematic and clinical review of laparoscopic adjustable gastric banding?

Output: a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic and clinical review of laparoscopic adjustable gastric banding?. ### Response: a meta-analysis.


Instruction: What does Roux-en-Y gastric bypass do for weight loss in adults?

Output: bariatric surgery and weight losing: a meta-analysis in the long- and very long-term effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Roux-en-Y gastric bypass do for weight loss in adults?. ### Response: bariatric surgery and weight losing: a meta-analysis in the long- and very long-term effects.


Instruction: When did JAMA issue 311:74-86?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 311:74-86?. ### Response: 2014.


Instruction: What is the effect of gastrectomy on weight loss in adults?

Output: long-term effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of gastrectomy on weight loss in adults?. ### Response: long-term effects.


Instruction: What study did Newman AB, Lee JS, Visser M, et al. study on weight change and the preservation of lean mass in old age?

Output: Health, Aging and Body Composition Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study did Newman AB, Lee JS, Visser M, et al. study on weight change and the preservation of lean mass in old age?. ### Response: Health, Aging and Body Composition Study.


Instruction: What are the health consequences of obe-sity in the elderly?

Output: a review of four unresolved questions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the health consequences of obe-sity in the elderly?. ### Response: a review of four unresolved questions.


Instruction: How many unresolved questions did Zamboni M, Mazzali G, Zoico E, et al. have?

Output: four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many unresolved questions did Zamboni M, Mazzali G, Zoico E, et al. have?. ### Response: four.


Instruction: What is the danger of weight loss in the older age group?

Output: coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the danger of weight loss in the older age group?. ### Response: coronary heart disease.


Instruction: In the elderly, what does J Nutr Health Aging. 2008:487-91?

Output: weight loss

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the elderly, what does J Nutr Health Aging. 2008:487-91?. ### Response: weight loss.


Instruction: What does lifestyle intervention or metformin reduce the incidence of?

Output: type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lifestyle intervention or metformin reduce the incidence of?. ### Response: type 2 diabetes.


Instruction: In 2002, what was the N Engl J Med 346:393-403.

Output: Reduction in the incidence of type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 2002, what was the N Engl J Med 346:393-403.. ### Response: Reduction in the incidence of type 2 diabetes.


Instruction: What does intensive lifestyle intervention do for type 2 diabetes?

Output: Cardiovascular effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does intensive lifestyle intervention do for type 2 diabetes?. ### Response: Cardiovascular effects.


Instruction: What does N Engl J Med 2013 369:145–54 say about cardiovascular effects of intensive lifestyle interventions?

Output: Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does N Engl J Med 2013 369:145–54 say about cardiovascular effects of intensive lifestyle interventions?. ### Response: Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.


Instruction: Who wrote the summary of the evidence for the US Preventive Services Task Force?

Output: McTigue

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the summary of the evidence for the US Preventive Services Task Force?. ### Response: McTigue.


Instruction: What is a summary of the evidence for the US Preventive Services Task Force?

Output: Screening and inter -ventions for obesity in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a summary of the evidence for the US Preventive Services Task Force?. ### Response: Screening and inter -ventions for obesity in adults.


Instruction: What is the summary of updated NICE guidance?

Output: Identification, assessment, and management of overweight and obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the summary of updated NICE guidance?. ### Response: Identification, assessment, and management of overweight and obesity.


Instruction: Who Expert Consultation. Appropriate body-mass index for Asian populations.

Output: WHO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who Expert Consultation. Appropriate body-mass index for Asian populations.. ### Response: WHO.


Instruction: WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for what?

Output: policy and intervention strate-gies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for what?. ### Response: policy and intervention strate-gies.


Instruction: What is a major lipid, apolipo-protein, and risk of vascular disease?

Output: lipids, apolipo-proteins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major lipid, apolipo-protein, and risk of vascular disease?. ### Response: lipids, apolipo-proteins.


Instruction: When did JAMA issue 302:1993-2000?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 302:1993-2000?. ### Response: 2009.


Instruction: What is the name of the study that focuses on the Stroke Study?

Output: Emerging Risk Factors Collaboration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that focuses on the Stroke Study?. ### Response: Emerging Risk Factors Collaboration.


Instruction: What is a risk factor for stroke inci-dence and mortality: a 12-year follow-up of a stroke victim?

Output: Cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for stroke inci-dence and mortality: a 12-year follow-up of a stroke victim?. ### Response: Cholesterol.


Instruction: What is the risk of ischemic stroke?

Output: Cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of ischemic stroke?. ### Response: Cholesterol.


Instruction: How long did the Oslo Study follow-up on stroke?

Output: 12-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Oslo Study follow-up on stroke?. ### Response: 12-year.


Instruction: What is the name of the study that followed the Oslo study?

Output: Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that followed the Oslo study?. ### Response: Stroke Study.


Instruction: When was this study published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 28, 2023.


Instruction: What is the event-free survival rate at 2 years in those with a jet velocity 3.0 m/s?

Output: 30% to 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the event-free survival rate at 2 years in those with a jet velocity 3.0 m/s?. ### Response: 30% to 50%.


Instruction: What does the rate of symptom onset depend on?

Output: the severity of AS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the rate of symptom onset depend on?. ### Response: the severity of AS.


Instruction: What percentage of patients with asymptomatic AS require periodic monitoring for development of symptoms and progressive disease?

Output: 30% to 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with asymptomatic AS require periodic monitoring for development of symptoms and progressive disease?. ### Response: 30% to 50%.


Instruction: Patients with moderate calcific AS undergoing cardiac surgery for other indications require what?

Output: prosthetic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with moderate calcific AS undergoing cardiac surgery for other indications require what?. ### Response: prosthetic valve.


Instruction: What is the risk of progressive VHD balanced against?

Output: the risk of repeat surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of progressive VHD balanced against?. ### Response: the risk of repeat surgery.


Instruction: What must be individualized on the basis of the specific operative risk?

Output: the risk of progressive VHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be individualized on the basis of the specific operative risk?. ### Response: the risk of progressive VHD.


Instruction: What are clini-cal factors such as age and comorbid conditions, valve durability, and patient preferences?

Output: This decision must be individualized on the basis of the specific operative risk in each patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are clini-cal factors such as age and comorbid conditions, valve durability, and patient preferences?. ### Response: This decision must be individualized on the basis of the specific operative risk in each patient.


Instruction: What are the recommendations summarized in Online Data Supplements 11 and 12.

Output: Referenced studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations summarized in Online Data Supplements 11 and 12.. ### Response: Referenced studies.


Instruction: What should be based on in patients with an indication for AVR?

Output: individual patient factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be based on in patients with an indication for AVR?. ### Response: individual patient factors.


Instruction: What should include discussion of the indications for and risks of the prosthetic valve?

Output: shared decision-making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should include discussion of the indications for and risks of the prosthetic valve?. ### Response: shared decision-making.


Instruction: What is a risk associated with valve reintervention?

Output: potential need for

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk associated with valve reintervention?. ### Response: potential need for.


Instruction: What type of therapy is contraindicated for patients of any age requiring AVR for whom VKA anticoagulant therapy is not desired?

Output: bioprosthetic AVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is contraindicated for patients of any age requiring AVR for whom VKA anticoagulant therapy is not desired?. ### Response: bioprosthetic AVR.


Instruction: What is recommended for patients 50 years of age who do not have a contraindication to anticoagulation and require AVR?

Output: mechanical aortic prosthesis over a bioprosthetic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients 50 years of age who do not have a contraindication to anticoagulation and require AVR?. ### Response: mechanical aortic prosthesis over a bioprosthetic valve.


Instruction: What is reasonable to choose a mechanical aortic prosthesis over a bioprosthetic valve?

Output: For patients <50 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to choose a mechanical aortic prosthesis over a bioprosthetic valve?. ### Response: For patients <50 years of age.


Instruction: What type of prosthesis is preferred over a bioprosthetic valve?

Output: mechanical aortic prosthesis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of prosthesis is preferred over a bioprosthetic valve?. ### Response: mechanical aortic prosthesis.


Instruction: What age range are patients who require AVR and who do not have a contraindication to anticoagulation?

Output: 50 to 65 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What age range are patients who require AVR and who do not have a contraindication to anticoagulation?. ### Response: 50 to 65 years of age.


Instruction: What type of AVR with consideration of individual patient factors and after informed shared decision-making?

Output: mechanical or bioprosthetic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of AVR with consideration of individual patient factors and after informed shared decision-making?. ### Response: mechanical or bioprosthetic.


Instruction: In patients >65 years of age who require AVR, it is reasonable to choose a bioprosthesis over a mechanical valve?

Output: Mechanical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients >65 years of age who require AVR, it is reasonable to choose a bioprosthesis over a mechanical valve?. ### Response: Mechanical.


Instruction: What is a pulmonic autograft?

Output: the Ross procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pulmonic autograft?. ### Response: the Ross procedure.


Instruction: What is the Ross procedure?

Output: pulmonic autograft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Ross procedure?. ### Response: pulmonic autograft.


Instruction: Where can a prosthetic valve be replaced?

Output: Comprehensive Valve Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can a prosthetic valve be replaced?. ### Response: Comprehensive Valve Center.


Instruction: What is influenced by several factors?

Output: Shared decision-making about the choice of pros-thetic valve type

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is influenced by several factors?. ### Response: Shared decision-making about the choice of pros-thetic valve type.


Instruction: When was this publication downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication downloaded?. ### Response: April 28, 2023.


Instruction: What is fondaparinux an indirect factor Xainhibitor but has no effect on thrombin?

Output: pentasaccharide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is fondaparinux an indirect factor Xainhibitor but has no effect on thrombin?. ### Response: pentasaccharide.


Instruction: What should be administered be-cause of the risk of catheter thrombosis?

Output: anti-IIa activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be administered be-cause of the risk of catheter thrombosis?. ### Response: anti-IIa activity.


Instruction: What does the writing committee recommend during primary PCI?

Output: an anticoagulant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing committee recommend during primary PCI?. ### Response: an anticoagulant.


Instruction: What is the standard dose of UFH with GP IIb/IIIa inhibitors?

Output: 85 U/kg, 60U/kg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the standard dose of UFH with GP IIb/IIIa inhibitors?. ### Response: 85 U/kg, 60U/kg.


Instruction: What is a low dose of GP IIb/IIIa inhibitors?

Output: 50 U/kg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a low dose of GP IIb/IIIa inhibitors?. ### Response: 50 U/kg.


Instruction: What is the level of evidence for no-reflow therapies?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for no-reflow therapies?. ### Response: B.


Instruction: What is a broad term used to describe 2 distinctentities?

Output: No-reflow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a broad term used to describe 2 distinctentities?. ### Response: No-reflow.


Instruction: The first is what?

Output: interventional no-reflow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The first is what?. ### Response: interventional no-reflow.


Instruction: What is the second entity?

Output: suboptimalreperfusion of an infarct artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the second entity?. ### Response: suboptimalreperfusion of an infarct artery.


Instruction: What is the second entity that causes suboptimalperfusion of an infarct artery?

Output: endothelialinjury

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the second entity that causes suboptimalperfusion of an infarct artery?. ### Response: endothelialinjury.


Instruction: What are the other two entities that cause suboptimallyperfusion?

Output: embolization and vasospasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the other two entities that cause suboptimallyperfusion?. ### Response: embolization and vasospasm.


Instruction: Which is the most obvious sequela of the samepathophysiology that produces abnormal TIMI frame counts?

Output: Angio-graphic no-reflow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which is the most obvious sequela of the samepathophysiology that produces abnormal TIMI frame counts?. ### Response: Angio-graphic no-reflow.


Instruction: What is the principal clinical sequela of no-reflow?

Output: myonecrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the principal clinical sequela of no-reflow?. ### Response: myonecrosis.


Instruction: Efforts to prevent what overlap with efforts to reduce MI size and prevent periprocedural MI?

Output: no-reflow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Efforts to prevent what overlap with efforts to reduce MI size and prevent periprocedural MI?. ### Response: no-reflow.


Instruction: In the setting of MI, several drugs have been shown to reduce what?

Output: the incidence of no-reflow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the setting of MI, several drugs have been shown to reduce what?. ### Response: the incidence of no-reflow.


Instruction: What are some of the agents that have been shown to have a beneficial effect on no-reflow?

Output: adeno-sine, calcium channel blockers, and nitroprus-side

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the agents that have been shown to have a beneficial effect on no-reflow?. ### Response: adeno-sine, calcium channel blockers, and nitroprus-side.


Instruction: What are two of the hard clinical endpoints that have influenced their adoption into clinical practice?

Output: infarct size andmortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two of the hard clinical endpoints that have influenced their adoption into clinical practice?. ### Response: infarct size andmortality.


Instruction: What has been limited for interventional no-reflow?

Output: hard clinical endpoints

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been limited for interventional no-reflow?. ### Response: hard clinical endpoints.


Instruction: What have several therapies proveneffective after no reflow has started?

Output: interventional no-reflow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have several therapies proveneffective after no reflow has started?. ### Response: interventional no-reflow.


Instruction: There are fewer data to support the use of what?

Output: epinephrine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are fewer data to support the use of what?. ### Response: epinephrine.


Instruction: How many studies have shown that pre-PCI intracoro-nary verapamil, nicardipine, and adenosine are safe?

Output: Trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have shown that pre-PCI intracoro-nary verapamil, nicardipine, and adenosine are safe?. ### Response: Trials.


Instruction: What has not shown reductions in post- PCI no-reflow?

Output: Trials of pre-PCI intracoro-nary verapamil, nicardipine, and adenosine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not shown reductions in post- PCI no-reflow?. ### Response: Trials of pre-PCI intracoro-nary verapamil, nicardipine, and adenosine.


Instruction: Mechanical devices to prevent what?

Output: interventional and myocardial infarct reperfusion no-reflow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Mechanical devices to prevent what?. ### Response: interventional and myocardial infarct reperfusion no-reflow.


Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3827 742.

Output: 757–764

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3827 742.. ### Response: 757–764.


Instruction: What does Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea?

Output: results of a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea?. ### Response: results of a meta-analysis.


Instruction: Sleep. 2004;27:249–253.

Output: 743

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sleep. 2004;27:249–253.. ### Response: 743.


Instruction: What is obstructive sleep apnea?

Output: Effect of nocturnal nasal con-tinuous positive airway pressure on blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is obstructive sleep apnea?. ### Response: Effect of nocturnal nasal con-tinuous positive airway pressure on blood pressure.


Instruction: What is the use of auto-titrating continuous positive airway pressure for?

Output: treatment of adult obstructive sleep apnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use of auto-titrating continuous positive airway pressure for?. ### Response: treatment of adult obstructive sleep apnea.


Instruction: What is the Cochrane Database Syst Rev. 2004:CD003531?

Output: Interventions to improve compliance with continuous positive airway pressure for obstructive sleep apnoea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Cochrane Database Syst Rev. 2004:CD003531?. ### Response: Interventions to improve compliance with continuous positive airway pressure for obstructive sleep apnoea.


Instruction: What is a treatment for obstructive sleep apnea?

Output: Positive airway pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a treatment for obstructive sleep apnea?. ### Response: Positive airway pressure.


Instruction: What did Smith I and Lasserson TJ use to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea?

Output: Educational, supportive and behavioural interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Smith I and Lasserson TJ use to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea?. ### Response: Educational, supportive and behavioural interventions.


Instruction: What did Cochrane Database Syst Rev. 2009:CD003531?

Output: Pressure modification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database Syst Rev. 2009:CD003531. 747

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Cochrane Database Syst Rev. 2009:CD003531?. ### Response: Pressure modification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database Syst Rev. 2009:CD003531. 747.


Instruction: What are interventions to improve usage of for adults with obstructive sleep apnoea?

Output: continuous positive airway pressure machines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are interventions to improve usage of for adults with obstructive sleep apnoea?. ### Response: continuous positive airway pressure machines.


Instruction: Cochrane Database Syst Rev. 2009:CD007736. 748.

Output: obstructive sleep apnoea. Cochrane Database Syst Rev. 2009:CD003531. 747. Smith I, Nadig V , Lasserson TJ. Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines for adults with obstructive sleep apnoea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cochrane Database Syst Rev. 2009:CD007736. 748.. ### Response: obstructive sleep apnoea. Cochrane Database Syst Rev. 2009:CD003531. 747. Smith I, Nadig V , Lasserson TJ. Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines for adults with obstructive sleep apnoea.


Instruction: What is long-term use of CPAP therapy for?

Output: sleep apnea/hypopnea syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is long-term use of CPAP therapy for?. ### Response: sleep apnea/hypopnea syndrome.


Instruction: What is a risk factor for sleep apnea?

Output: nocturnal nasal con-tinuous positive airway pressure on blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for sleep apnea?. ### Response: nocturnal nasal con-tinuous positive airway pressure on blood pressure.


Instruction: What is the name of the study that examined the association between sleep-disordered breathing and hypertension?

Output: Prospective study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the association between sleep-disordered breathing and hypertension?. ### Response: Prospective study.


Instruction: What is obstructive sleep apnoea syn-drome as a risk factor for hypertension?

Output: population study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is obstructive sleep apnoea syn-drome as a risk factor for hypertension?. ### Response: population study.


Instruction: BMJ. 2000;320:479–482.

Output: 751

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BMJ. 2000;320:479–482.. ### Response: 751.


Instruction: Logan AG, Perlikowski SM, Mente A, Tisler A, Tkacova R, Niroumand M, Leung RS, Bradley TD. High prevalence of what in drug-resistant hypertension.

Output: unrecognized sleep apnoea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Logan AG, Perlikowski SM, Mente A, Tisler A, Tkacova R, Niroumand M, Leung RS, Bradley TD. High prevalence of what in drug-resistant hypertension.. ### Response: unrecognized sleep apnoea.


Instruction: J Hypertens 2001;19:2271–2277.

Output: 752

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Hypertens 2001;19:2271–2277.. ### Response: 752.


Instruction: What is the effect of nocturnal nasal con-tinuous positive airway pressure on blood pressure in obstructive sleep apnea?

Output: 417–423. 753

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of nocturnal nasal con-tinuous positive airway pressure on blood pressure in obstructive sleep apnea?. ### Response: 417–423. 753.


Instruction: What is the effect of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syn-drome?

Output: evidence from a meta-analysis of placebo-controlled randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syn-drome?. ### Response: evidence from a meta-analysis of placebo-controlled randomized trials.


Instruction: What did De Weerdt S, Poppe K, Dupont A, Velkeniers B?

Output: Meerhaeghe A, Moscariello A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did De Weerdt S, Poppe K, Dupont A, Velkeniers B?. ### Response: Meerhaeghe A, Moscariello A.


Instruction: What is the effect of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopneua?

Output: improve compliance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopneua?. ### Response: improve compliance.


Instruction: What is a meta-analysis of randomized controlled trials?

Output: Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of randomized controlled trials?. ### Response: Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopnea.


Instruction: What is the name of the study that examined sleep disorders and sleep deprivation?

Output: An Unmet Public Health Problem

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined sleep disorders and sleep deprivation?. ### Response: An Unmet Public Health Problem.


Instruction: What was the title of this study?

Output: meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of this study?. ### Response: meta-analysis.


Instruction: What type of oxygen therapy is recommended in people with advanced heart failure?

Output: Domiciliary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of oxygen therapy is recommended in people with advanced heart failure?. ### Response: Domiciliary.


Instruction: In what year did NICE publish a study on Chronic Heart Failure Domiciliary oxygen therapy?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did NICE publish a study on Chronic Heart Failure Domiciliary oxygen therapy?. ### Response: 2018.


Instruction: Whose prognosis highlights the importance of an immediate follow up consultation?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Whose prognosis highlights the importance of an immediate follow up consultation?. ### Response: Chronic Heart Failure.


Instruction: What type of consultation provides reinforcement of the key implications of the diagnosis and prognosis?

Output: immediat e follow -up consultation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of consultation provides reinforcement of the key implications of the diagnosis and prognosis?. ### Response: immediat e follow -up consultation.


Instruction: What provides clarification of any misperceptions?

Output: family member or carer is present

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides clarification of any misperceptions?. ### Response: family member or carer is present.


Instruction: What did the consultant committee members suggest to facilitate a quick rapport with the patient and tailor information to the patient’s needs?

Output: including any preferences the patient had, regarding the level and type of information they want to be given, into the referral form from primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the consultant committee members suggest to facilitate a quick rapport with the patient and tailor information to the patient’s needs?. ### Response: including any preferences the patient had, regarding the level and type of information they want to be given, into the referral form from primary care.


Instruction: What type of information did the patient want to be given?

Output: level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of information did the patient want to be given?. ### Response: level.


Instruction: What did patients complete before the first appointment?

Output: a simple questionnaire

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients complete before the first appointment?. ### Response: a simple questionnaire.


Instruction: What did the heart failure committee want to discuss during the consultation?

Output: Trade -off between net effects and costs  No previous ly published economic evaluations were identified for this question.  The committee considered that overall the recommendations made above in conjunction with the patient experience guideline would improve patient satisfaction and help reduce anxiety about  their condition and as a result lead to an improvement in quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the heart failure committee want to discuss during the consultation?. ### Response: Trade -off between net effects and costs  No previous ly published economic evaluations were identified for this question.  The committee considered that overall the recommendations made above in conjunction with the patient experience guideline would improve patient satisfaction and help reduce anxiety about  their condition and as a result lead to an improvement in quality of life.


Instruction: What skills did the committee acknowledge that not all healthcare professionals have?

Output: communication of these challenging issues requires specific skills

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What skills did the committee acknowledge that not all healthcare professionals have?. ### Response: communication of these challenging issues requires specific skills.


Instruction: The committee supported the provision of what to all heart failure staff?

Output: trainin g in advanced communication skills

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee supported the provision of what to all heart failure staff?. ### Response: trainin g in advanced communication skills.


Instruction: What could be incorporated into broader communication training for chronic or life limiting conditions?

Output: Specific information on heart failure issues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be incorporated into broader communication training for chronic or life limiting conditions?. ### Response: Specific information on heart failure issues.


Instruction: The importance of consistency was discussed.

Output: The majority of the recommendations made above will not incur any cost as they simply specify what information should be given to patients and the manner in which it should be delivered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The importance of consistency was discussed.. ### Response: The majority of the recommendations made above will not incur any cost as they simply specify what information should be given to patients and the manner in which it should be delivered.


Instruction: What should the patient receive from all MDT members?

Output: consistent information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the patient receive from all MDT members?. ### Response: consistent information.


Instruction: What did the committee recognise was closely linked to the separate evidence review?

Output: consistent information from all MDT members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee recognise was closely linked to the separate evidence review?. ### Response: consistent information from all MDT members.


Instruction: What was the need for printed leaflets on heart failure to be available within the NHS?

Output: patients value the provision of information that they can take away with them to read and absorb in their own time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the need for printed leaflets on heart failure to be available within the NHS?. ### Response: patients value the provision of information that they can take away with them to read and absorb in their own time.


Instruction: What was unanimously agreed by the committee on heart failure to be available within the NHS?

Output: The need for printed leaflets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was unanimously agreed by the committee on heart failure to be available within the NHS?. ### Response: The need for printed leaflets.


Instruction: Patients value the provision of information that they can take away with them to read and absorb in their own time?

Output: The need for printed leaflets on heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients value the provision of information that they can take away with them to read and absorb in their own time?. ### Response: The need for printed leaflets on heart failure.


Instruction: The committee acknowledged that patients need to be directed to what?

Output: reliable  sources of information outside the NHS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee acknowledged that patients need to be directed to what?. ### Response: reliable  sources of information outside the NHS.


Instruction: Who acknowledged that patients need to be directed to reliable sources of information outside the NHS?

Output: The committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who acknowledged that patients need to be directed to reliable sources of information outside the NHS?. ### Response: The committee.


Instruction: What was the trade-off between net effects and costs?

Output: No previous ly published economic evaluations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the trade-off between net effects and costs?. ### Response: No previous ly published economic evaluations.


Instruction: What type of evaluations were identified for this question?

Output: No previous ly published economic evaluations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of evaluations were identified for this question?. ### Response: No previous ly published economic evaluations.


Instruction: What did the committee consider would improve patient satisfaction and help reduce anxiety about?

Output: their condition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee consider would improve patient satisfaction and help reduce anxiety about?. ### Response: their condition.


Instruction: What does the majority of the recommendations do not incur?

Output: any cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the majority of the recommendations do not incur?. ### Response: any cost.


Instruction: What do the recommendations specify?

Output: what information should be given to patients and the manner in which it should be delivered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the recommendations specify?. ### Response: what information should be given to patients and the manner in which it should be delivered.


Instruction: The committee acknowledged that some of the recommendations could have what?

Output: cost implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee acknowledged that some of the recommendations could have what?. ### Response: cost implications.


Instruction: What was associated with an absolute reduction in risk of death of 0.7%?

Output: supplemented diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with an absolute reduction in risk of death of 0.7%?. ### Response: supplemented diet.


Instruction: What did early tube feeding (within 7 days of admission) cause?

Output: an absolute reduction in risk of death of 5.8% and a reduction in death or poor outcomes of 1.2%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did early tube feeding (within 7 days of admission) cause?. ### Response: an absolute reduction in risk of death of 5.8% and a reduction in death or poor outcomes of 1.2%..


Instruction: How much was the reduction in death or poor outcomes of supplemented diet?

Output: 1.2%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the reduction in death or poor outcomes of supplemented diet?. ### Response: 1.2%..


Instruction: What was the reduction in death or poor outcomes of nasogastric feeding and percutaneous endoscopic gastrostomy feeding compared to?

Output: increased risk of death or poor outcomes of 7.8%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in death or poor outcomes of nasogastric feeding and percutaneous endoscopic gastrostomy feeding compared to?. ### Response: increased risk of death or poor outcomes of 7.8%..


Instruction: What was associated with an increase in absolute risk of death of 1.0%?

Output: percutaneous endoscopic gastrostomy feeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with an increase in absolute risk of death of 1.0%?. ### Response: percutaneous endoscopic gastrostomy feeding.


Instruction: How much was the increase in risk of poor outcomes?

Output: 7.8%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the increase in risk of poor outcomes?. ### Response: 7.8%..


Instruction: What percentage of stroke patients died or had poor outcomes?

Output: 7.8%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of stroke patients died or had poor outcomes?. ### Response: 7.8%..


Instruction: What should stroke patients be started on within the first 7 days of admission?

Output: enteral diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should stroke patients be started on within the first 7 days of admission?. ### Response: enteral diet.


Instruction: How many RCTs did a Cochrane review analyze in 2012?

Output: 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs did a Cochrane review analyze in 2012?. ### Response: 33.


Instruction: How long does it take for dysphagia to be treated?

Output: within 7 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for dysphagia to be treated?. ### Response: within 7 days.


Instruction: What did the study conclude about the effects of nutritional supplementation on acute and subacute stroke patients?

Output: stroke patients should be started on enteral diet within the first 7 days of admission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the study conclude about the effects of nutritional supplementation on acute and subacute stroke patients?. ### Response: stroke patients should be started on enteral diet within the first 7 days of admission.


Instruction: Percutaneous endoscopic gastrostomy feeding and nasogastric tube feeding do not differ in terms of what?

Output: case fatality, death, or dependency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Percutaneous endoscopic gastrostomy feeding and nasogastric tube feeding do not differ in terms of what?. ### Response: case fatality, death, or dependency.


Instruction: What is associated with fewer treatment failures?

Output: percutaneous endoscopic gastrostomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with fewer treatment failures?. ### Response: percutaneous endoscopic gastrostomy.


Instruction: What is the P value for delivery?

Output: P<0.00001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the P value for delivery?. ### Response: P<0.00001.


Instruction: What is a reasonable consideration for patients who are malnourished or at risk of malnourishment?

Output: Nutritional supplements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable consideration for patients who are malnourished or at risk of malnourishment?. ### Response: Nutritional supplements.


Instruction: How was the LOE amended to conform with ACC/AHA 2015 Recommendation Classification System?

Output: 2016 Rehab Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the LOE amended to conform with ACC/AHA 2015 Recommendation Classification System?. ### Response: 2016 Rehab Guidelines.


Instruction: What is the 2015 Recommendation Classification System?

Output: ACC/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2015 Recommendation Classification System?. ### Response: ACC/AHA.


Instruction: What is recommended in immobile stroke patients without contraindications?

Output: intermittent pneumatic compression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in immobile stroke patients without contraindications?. ### Response: intermittent pneumatic compression.


Instruction: What is the term for deep vein thrombosis?

Output: DVT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for deep vein thrombosis?. ### Response: DVT.


Instruction: When was the B-RRecommendation revised?

Output: 2016 Rehab Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the B-RRecommendation revised?. ### Response: 2016 Rehab Guidelines.


Instruction: What is acute he art failur e: diagnosis and manag emen t Clinical guideline Published: 8 Oct ober 2014 www.nice.or g.uk/guidance/cg187  NICE 2022 What is the Subject t o Notice of right s?

Output: All right s reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is acute he art failur e: diagnosis and manag emen t Clinical guideline Published: 8 Oct ober 2014 www.nice.or g.uk/guidance/cg187  NICE 2022 What is the Subject t o Notice of right s?. ### Response: All right s reserved.


Instruction: What is associated with a very low annual risk of cardiac death and AMI in both men and women?

Output: A normal exercise nuclear MPI study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with a very low annual risk of cardiac death and AMI in both men and women?. ### Response: A normal exercise nuclear MPI study.


Instruction: What is associated with a low frequence of referral for coronary revascularization or worsening clinical status and UA admission?

Output: Normal and mildly abnormal nuclear MPI or exercisestress echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with a low frequence of referral for coronary revascularization or worsening clinical status and UA admission?. ### Response: Normal and mildly abnormal nuclear MPI or exercisestress echocardiography.


Instruction: What percentage of referrals are associated with mildly abnormal nuclear MPI or exercisestress echocardiography?

Output: 1.3% and1%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of referrals are associated with mildly abnormal nuclear MPI or exercisestress echocardiography?. ### Response: 1.3% and1%.


Instruction: What is the name of the supplement that Kidney International Supplements (2012) 2?

Output: Not Graded

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the supplement that Kidney International Supplements (2012) 2?. ### Response: Not Graded.


Instruction: What are the names of the recommendations statements?

Output: 341–342

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the recommendations statements?. ### Response: 341–342.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett et al.


Instruction: What is the name of the guideline for the primary prevention of cardiovascular disease?

Output: ACC/AHA Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for the primary prevention of cardiovascular disease?. ### Response: ACC/AHA Guideline.


Instruction: When was the Cochrane Database Syst Rev. published?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Cochrane Database Syst Rev. published?. ### Response: 2013.


Instruction: What is the Cochrane Database Syst Rev. 2013 CD004816?

Output: S4.3-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Cochrane Database Syst Rev. 2013 CD004816?. ### Response: S4.3-9.


Instruction: What is lowering in inter-mediate-risk persons without cardiovascular disease?

Output: Cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lowering in inter-mediate-risk persons without cardiovascular disease?. ### Response: Cholesterol.


Instruction: When did N Engl J Med. 2016;374:2021-31?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med. 2016;374:2021-31?. ### Response: 2016.


Instruction: What is atorvastatin used for in type 2 diabetes?

Output: Reduction in cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atorvastatin used for in type 2 diabetes?. ### Response: Reduction in cardiovascular events.


Instruction: What is the name of the multicentre randomised placebo-controlled trial?

Output: Collaborative Atorvastatin Diabetes Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicentre randomised placebo-controlled trial?. ### Response: Collaborative Atorvastatin Diabetes Study.


Instruction: What is the acronym for Collaborative Atorvastatin Diabetes Study?

Output: CARDS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Collaborative Atorvastatin Diabetes Study?. ### Response: CARDS.


Instruction: How many people were enrolled in the MRC/BHF Heart Protection Study in 2003?

Output: 5963

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the MRC/BHF Heart Protection Study in 2003?. ### Response: 5963.


Instruction: What is the primary prevention of major cardiovascular and cerebrovascular events with statins in diabetic patients: a meta-analysis?

Output: wels KB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention of major cardiovascular and cerebrovascular events with statins in diabetic patients: a meta-analysis?. ### Response: wels KB.


Instruction: What is Knopp RH, d’Emden M, and Smilde JG?

Output: Efficacy and safety of atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Knopp RH, d’Emden M, and Smilde JG?. ### Response: Efficacy and safety of atorvastatin.


Instruction: What is atorvastatin used for in the prevention of cardiovascular endpoints in sub-jects with type 2 diabetes?

Output: Efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atorvastatin used for in the prevention of cardiovascular endpoints in sub-jects with type 2 diabetes?. ### Response: Efficacy and safety.


Instruction: What is the ASPEN?

Output: Atorvastatin Study for Prevention of Coronary Heart Disease Endpoints in non-insulin-dependent diabe-tes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ASPEN?. ### Response: Atorvastatin Study for Prevention of Coronary Heart Disease Endpoints in non-insulin-dependent diabe-tes mellitus.


Instruction: When did Diabetes Care. 2006;29:1478-85.

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Diabetes Care. 2006;29:1478-85.. ### Response: 2006.


Instruction: What is risk of myocardial infarc-tion in men and women with type 2 diabetes in the UK?

Output: S4.3-15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is risk of myocardial infarc-tion in men and women with type 2 diabetes in the UK?. ### Response: S4.3-15.


Instruction: What is the name of the cohort study using the General Practice Research Database?

Output: Risk of myocardial infarc-tion in men and women with type 2 diabetes in the UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the cohort study using the General Practice Research Database?. ### Response: Risk of myocardial infarc-tion in men and women with type 2 diabetes in the UK.


Instruction: In what year was the Journal of Diabetologia published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Journal of Diabetologia published?. ### Response: 2008.


Instruction: What are not necessarily risk equivalent for future coronary heart disease events?

Output: Diabetes and prior coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are not necessarily risk equivalent for future coronary heart disease events?. ### Response: Diabetes and prior coronary heart disease.


Instruction: How many patients with type 2 diabetes were treated with atorvastatin in 2005?

Output: 2 532

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with type 2 diabetes were treated with atorvastatin in 2005?. ### Response: 2 532.


Instruction: What is the ASCOT-LLA?

Output: Anglo-Scandinavian Cardiac Outcomes Trial—lipid-lowering arm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ASCOT-LLA?. ### Response: Anglo-Scandinavian Cardiac Outcomes Trial—lipid-lowering arm.


Instruction: What is ASCOT-LLA?

Output: Anglo-Scandinavian Cardiac Outcomes Trial—lipid-lowering arm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ASCOT-LLA?. ### Response: Anglo-Scandinavian Cardiac Outcomes Trial—lipid-lowering arm.


Instruction: What is the name of the lipid-lowering arm of the Anglo-Scandinavian Cardiac Outcomes Trial?

Output: ASCOT-LLA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the lipid-lowering arm of the Anglo-Scandinavian Cardiac Outcomes Trial?. ### Response: ASCOT-LLA.


Instruction: When was the Diabetes Care.28:1151–7?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Diabetes Care.28:1151–7?. ### Response: 2005.


Instruction: How was the high risk of cardio-vascular disease in patients with type 1 diabetes in the U.K. used?

Output: general practice research database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the high risk of cardio-vascular disease in patients with type 1 diabetes in the U.K. used?. ### Response: general practice research database.


Instruction: What is the name of the diabetes research database?

Output: General Practice Research Database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the diabetes research database?. ### Response: General Practice Research Database.


Instruction: What are statins used for in familial hyper -activity disorder?

Output: lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are statins used for in familial hyper -activity disorder?. ### Response: lowering.


Instruction: What is NICE 2018?

Output: All rights reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: All rights reserved.


Instruction: What is the study design and sample size?

Output: Finding  Quality assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the study design and sample size?. ### Response: Finding  Quality assessment.


Instruction: How many studies contribute to the finding?

Output: Number

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies contribute to the finding?. ### Response: Number.


Instruction: How many studies contributed to the finding?

Output: Number

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies contributed to the finding?. ### Response: Number.


Instruction: What was the overall assessment of confidence?

Output: Adequacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall assessment of confidence?. ### Response: Adequacy.


Instruction: How was the diagnosis of heart failure determined?

Output: a gradual process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the diagnosis of heart failure determined?. ### Response: a gradual process.


Instruction: What type of study involves pt + carers and focus groups with HCPs?

Output: Individual interviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of study involves pt + carers and focus groups with HCPs?. ### Response: Individual interviews.


Instruction: What is seen as a gradual process which results in information and guidance around diagnosis being relayed to patients?

Output: The diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is seen as a gradual process which results in information and guidance around diagnosis being relayed to patients?. ### Response: The diagnosis.


Instruction: What are concerns about methodological limitations MODERATE Coherence No or very minor concerns about coherence Relevance No concerns about relevance Adequacy No worries about what?

Output: adequacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are concerns about methodological limitations MODERATE Coherence No or very minor concerns about coherence Relevance No concerns about relevance Adequacy No worries about what?. ### Response: adequacy.


Instruction: What is a concern about adequacy Diagnosis of heart failure 1d?

Output: No

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a concern about adequacy Diagnosis of heart failure 1d?. ### Response: No.


Instruction: Semi -structured interview s with pt + carers and focus groups with HCPs Secondary analysis of what?

Output: interview transcripts of pt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Semi -structured interview s with pt + carers and focus groups with HCPs Secondary analysis of what?. ### Response: interview transcripts of pt.


Instruction: What term is seen by healthcare professionals as anxiety-invoking?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What term is seen by healthcare professionals as anxiety-invoking?. ### Response: heart failure.


Instruction: What do many healthcare professionals make use of instead of simple terminology?

Output: euphemisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do many healthcare professionals make use of instead of simple terminology?. ### Response: euphemisms.


Instruction: What type of terminology is confusing for patients?

Output: euphemisms or even more complex terminology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of terminology is confusing for patients?. ### Response: euphemisms or even more complex terminology.


Instruction: What are some concerns about methodological limitations MODERATE Coherence?

Output: Minor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some concerns about methodological limitations MODERATE Coherence?. ### Response: Minor.


Instruction: What are some concerns about relevance?

Output: No or very minor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some concerns about relevance?. ### Response: No or very minor.


Instruction: What are other concerns?

Output: methodological limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are other concerns?. ### Response: methodological limitations.


Instruction: What do we suggest in children with CKD?

Output: annualfollow-up measurement of fasting lipid levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest in children with CKD?. ### Response: annualfollow-up measurement of fasting lipid levels.


Instruction: What does CHAPTER 4: PHARMACOLOGICAL CHOLESTEROL-LOWERING TREATMENT IN CHILDREN?

Output: annualfollow-up measurement of fasting lipid levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CHAPTER 4: PHARMACOLOGICAL CHOLESTEROL-LOWERING TREATMENT IN CHILDREN?. ### Response: annualfollow-up measurement of fasting lipid levels.


Instruction: What do we suggest not be initiated in adults with CKD?

Output: statins or statin/ezetimibecombination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest not be initiated in adults with CKD?. ### Response: statins or statin/ezetimibecombination.


Instruction: What are we suggesting that therapeutic lifestyle changes be advised?

Output: In adults with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are we suggesting that therapeutic lifestyle changes be advised?. ### Response: In adults with CKD.


Instruction: What should be advised in children with CKD?

Output: therapeutic lifestyle changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be advised in children with CKD?. ### Response: therapeutic lifestyle changes.


Instruction: What should therapeutic lifestyle changes beadvised?

Output: In children with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should therapeutic lifestyle changes beadvised?. ### Response: In children with CKD.


Instruction: Who wrote a synopsis of clinical practice guideline?

Output: Wanner et al.:

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote a synopsis of clinical practice guideline?. ### Response: Wanner et al.:.


Instruction: Wanner et al.: Synopsis of clinical practice guideline on lipid management in CKD review?

Output: therapeutic lifestyle changes be advised

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Wanner et al.: Synopsis of clinical practice guideline on lipid management in CKD review?. ### Response: therapeutic lifestyle changes be advised.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the DOI: 10.1161/CIR.0000000000000923 February 2, 2021 e199CLINICAL STATEMENTS AND GUIDELINES

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI: 10.1161/CIR.0000000000000923 February 2, 2021 e199CLINICAL STATEMENTS AND GUIDELINES. ### Response: Otto et al.


Instruction: What is stenosis in sinus rhythm?

Output: moderate mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stenosis in sinus rhythm?. ### Response: moderate mitral.


Instruction: What is the name of the study that compares ivabradine and atenolol in patients with moderate mitral stenosis?

Output: Indian Heart J.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares ivabradine and atenolol in patients with moderate mitral stenosis?. ### Response: Indian Heart J..


Instruction: In what year did Indian Heart J.68:311–5 appear?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Indian Heart J.68:311–5 appear?. ### Response: 2016.


Instruction: Leenhardt A, Extramiana F. Management of atrial fibrillation in patients with rheumatic mitral stenosis. Heart. 2018;104:1062–8. 17. Krishnamoorthy KM. Incidence and predictors of what?

Output: left atrial thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Leenhardt A, Extramiana F. Management of atrial fibrillation in patients with rheumatic mitral stenosis. Heart. 2018;104:1062–8. 17. Krishnamoorthy KM. Incidence and predictors of what?. ### Response: left atrial thrombus.


Instruction: Echocardiography. 2012;29:876–7. 18. Manjunath CN, Srinivasa KH, Panneerselvam A, and others.

Output: transesopha-geal echocardiographic study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Echocardiography. 2012;29:876–7. 18. Manjunath CN, Srinivasa KH, Panneerselvam A, and others.. ### Response: transesopha-geal echocardiographic study.


Instruction: What is a common cause of left atrial thrombus in patients with rheumatic mitral stenosis and sinus rhythm?

Output: Incidence and pre-dictors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of left atrial thrombus in patients with rheumatic mitral stenosis and sinus rhythm?. ### Response: Incidence and pre-dictors.


Instruction: In what year did Echocar -diography publish a study on the incidence and pre-dictors of left ventricular thrombosis?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Echocar -diography publish a study on the incidence and pre-dictors of left ventricular thrombosis?. ### Response: 2012.


Instruction: What is used to assess thromboembolic risk in mitral stenosis?

Output: left atrial volume versus diameter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to assess thromboembolic risk in mitral stenosis?. ### Response: left atrial volume versus diameter.


Instruction: What is the impact of incorporating commissural morphology and leaflet displacement to the prediction of outcome for patients?

Output: The echo score revisited

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of incorporating commissural morphology and leaflet displacement to the prediction of outcome for patients?. ### Response: The echo score revisited.


Instruction: What does leaflet displacement do to the prediction of outcome for patients undergoing percutaneous mitral valvu-loplasty?

Output: incorporating commissural morphology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does leaflet displacement do to the prediction of outcome for patients undergoing percutaneous mitral valvu-loplasty?. ### Response: incorporating commissural morphology.


Instruction: What does Circulation. 2014;129:886-95?

Output: prediction of outcome for patients undergoing percutaneous mitral valvu-loplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Circulation. 2014;129:886-95?. ### Response: prediction of outcome for patients undergoing percutaneous mitral valvu-loplasty.


Instruction: Who developed and validated a risk score predicting late functional results from a series of patients?

Output: Bouleti C, Iung B, Laouénan C, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed and validated a risk score predicting late functional results from a series of patients?. ### Response: Bouleti C, Iung B, Laouénan C, et al.


Instruction: How many patients had a risk score predicting late functional results?

Output: 912

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had a risk score predicting late functional results?. ### Response: 912.


Instruction: What is the risk score of 912 patients?

Output: Cir -culation. 2012;125:2119–27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk score of 912 patients?. ### Response: Cir -culation. 2012;125:2119–27.


Instruction: How long is follow-up after percutaneous balloon mitral valvuloplasty?

Output: five-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is follow-up after percutaneous balloon mitral valvuloplasty?. ### Response: five-year.


Instruction: Percutaneous mitral valvoto-my versus closed surgical commissurotomy?

Output: Rifaie O

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Percutaneous mitral valvoto-my versus closed surgical commissurotomy?. ### Response: Rifaie O.


Instruction: Up to how long of follow-up of a prospective randomized study?

Output: 15 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Up to how long of follow-up of a prospective randomized study?. ### Response: 15 years.


Instruction: What is the name of the study that compares open commisurotomie and balloon valvuloplasty?

Output: Cardoso LF, Grinberg M, Pomerantzeff PMA, et al. Comparison of open commissurotomy and balloon valvuloplasty in mitral stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares open commisurotomie and balloon valvuloplasty?. ### Response: Cardoso LF, Grinberg M, Pomerantzeff PMA, et al. Comparison of open commissurotomy and balloon valvuloplasty in mitral stenosis.


Instruction: What is the difference between commissurotomy and balloon valvuloplasty in mitral stenosis?

Output: open

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between commissurotomy and balloon valvuloplasty in mitral stenosis?. ### Response: open.