Instruction: What type of care is provided in communities and clinical settings?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care is provided in communities and clinical settings?. ### Response: hypertension.


Instruction: What is the name of a national and regional initiative to improve hypertension?

Output: Million Hearts Make Control Your Goal Blood Pressure Toolkit and Team Up Pressure Down

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a national and regional initiative to improve hypertension?. ### Response: Million Hearts Make Control Your Goal Blood Pressure Toolkit and Team Up Pressure Down.


Instruction: What have shown greater SBP and DBP re-ductions?

Output: Systematic review and meta-analyses of trials of quality improvement interventions at health system, provider, and patient levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have shown greater SBP and DBP re-ductions?. ### Response: Systematic review and meta-analyses of trials of quality improvement interventions at health system, provider, and patient levels.


Instruction: What have multicomponent and multilevel strategies at the lo-cal community and healthcare delivery system been shown to improve?

Output: BP control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have multicomponent and multilevel strategies at the lo-cal community and healthcare delivery system been shown to improve?. ### Response: BP control.


Instruction: What is shown to improve BP control?

Output: Multicomponent and multilevel strategies at the lo-cal community and healthcare delivery system levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shown to improve BP control?. ### Response: Multicomponent and multilevel strategies at the lo-cal community and healthcare delivery system levels.


Instruction: What are recommendations that support recommendations summarized in?

Output: Online Data Supplement 68.COR LOE RecommendationsIIa B-R1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are recommendations that support recommendations summarized in?. ### Response: Online Data Supplement 68.COR LOE RecommendationsIIa B-R1.


Instruction: PCI for a hemodynamically significant stenosis in a patentinfarct artery as part of a revascu-larization strategy improves what?

Output: outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PCI for a hemodynamically significant stenosis in a patentinfarct artery as part of a revascu-larization strategy improves what?. ### Response: outcome.


Instruction: PCI of an anoccluded infarcting artery 1 to 28 days after MI has nocremental benefit beyond optimal medical therapy with what drugs?

Output: aspirin, beta blockers, angiotensin-converting enzyme inhib-itors, and statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PCI of an anoccluded infarcting artery 1 to 28 days after MI has nocremental benefit beyond optimal medical therapy with what drugs?. ### Response: aspirin, beta blockers, angiotensin-converting enzyme inhib-itors, and statins.


Instruction: What is the benefit of statins in preserving LV function and preventing cardiovascular events?

Output: optimal medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of statins in preserving LV function and preventing cardiovascular events?. ### Response: optimal medical therapy.


Instruction: What has not been studied in patients with New York Heart Associationfunctional class III or IV heart disease?

Output: elective PCI of an occluded infarct artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been studied in patients with New York Heart Associationfunctional class III or IV heart disease?. ### Response: elective PCI of an occluded infarct artery.


Instruction: What is recommended for patients with acute MI?

Output: PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with acute MI?. ### Response: PCI.


Instruction: What is the name of the class of heart failure?

Output: class III or IV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the class of heart failure?. ### Response: class III or IV.


Instruction: How is PCI recommended?

Output: PCI is recommended for patients with acute MI whodevelop cardiogenic shock and are suitable candi-dates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is PCI recommended?. ### Response: PCI is recommended for patients with acute MI whodevelop cardiogenic shock and are suitable candi-dates.


Instruction: What is recommended for patients with acute MI who have cardiogenic shock and are suitable candi-dates?

Output: PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with acute MI who have cardiogenic shock and are suitable candi-dates?. ### Response: PCI.


Instruction: What is a hemodynamic support device recommended for for patients who do not quickly stabilize with pharmacological ther-apy?

Output: cardiogenic shock after STEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a hemodynamic support device recommended for for patients who do not quickly stabilize with pharmacological ther-apy?. ### Response: cardiogenic shock after STEMI.


Instruction: What is the leading cause of in-hospitalmortality complicating STEMI?

Output: Cardiogenic shock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the leading cause of in-hospitalmortality complicating STEMI?. ### Response: Cardiogenic shock.


Instruction: Revascularization is the only treatment proven to decrease what?

Output: mortality rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Revascularization is the only treatment proven to decrease what?. ### Response: mortality rates.


Instruction: What type of disease can benefit from emergency CABG?

Output: 3-vessel or leftmain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of disease can benefit from emergency CABG?. ### Response: 3-vessel or leftmain.


Instruction: What may be futile and not indicated in cases of severe multiorgan failure?

Output: Revascu-larization attempts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be futile and not indicated in cases of severe multiorgan failure?. ### Response: Revascu-larization attempts.


Instruction: Patient selection for revascularization is more important in what age group?

Output: elderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patient selection for revascularization is more important in what age group?. ### Response: elderly.


Instruction: What are patients who present to hospitals without PCIcapability usually transported to?

Output: a PCI center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients who present to hospitals without PCIcapability usually transported to?. ### Response: a PCI center.


Instruction: What is markedly elevated without transfer?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is markedly elevated without transfer?. ### Response: mortality.


Instruction: How should patients with cardiogenic shock receive standardpharmacological therapies?

Output: aspirin, a P2Y12recep-tor antagonist, and anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should patients with cardiogenic shock receive standardpharmacological therapies?. ### Response: aspirin, a P2Y12recep-tor antagonist, and anticoagulation.


Instruction: What type of therapy improves perfusion pressure?

Output: Inotropic and vaso-pressor therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy improves perfusion pressure?. ### Response: Inotropic and vaso-pressor therapy.


Instruction: What are negative inotropes and vasodilators avoided?

Output: IV GPIIb/IIIa inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are negative inotropes and vasodilators avoided?. ### Response: IV GPIIb/IIIa inhibitors.


Instruction: How many small RCTs have shown IV GPIIb/IIIa inhibitors to provide benefit?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many small RCTs have shown IV GPIIb/IIIa inhibitors to provide benefit?. ### Response: 1.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is an elevated pulmonary arterial resistance before intervention associated with?

Output: RV dysfunction and TR after the procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an elevated pulmonary arterial resistance before intervention associated with?. ### Response: RV dysfunction and TR after the procedure.


Instruction: How can PMBC prevent the adverse consequences of irreversible pulmonary hypertension?

Output: if it can be performed with a high success rate and low risk in patients who are developing pulmonary hyper -tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can PMBC prevent the adverse consequences of irreversible pulmonary hypertension?. ### Response: if it can be performed with a high success rate and low risk in patients who are developing pulmonary hyper -tension.


Instruction: PMBC can be performed with a high success rate and low risk in patients who are developing what?

Output: pulmonary hyper -tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PMBC can be performed with a high success rate and low risk in patients who are developing what?. ### Response: pulmonary hyper -tension.


Instruction: What can be curative?

Output: Correction of the MR before irreversible changes occur

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be curative?. ### Response: Correction of the MR before irreversible changes occur.


Instruction: What can occur be curative?

Output: Correction of the MR before irreversible changes occur

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can occur be curative?. ### Response: Correction of the MR before irreversible changes occur.


Instruction: What is the disease in chronic primary MR?

Output: MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the disease in chronic primary MR?. ### Response: MR.


Instruction: The new onset of AF may be an indication for pro-ceeding with PMBC in what patient?

Output: asymptomatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The new onset of AF may be an indication for pro-ceeding with PMBC in what patient?. ### Response: asymptomatic.


Instruction: What is the equivalent of symptom onset?

Output: AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the equivalent of symptom onset?. ### Response: AF.


Instruction: What increases the risk of thromboembolic events in patients with rheumatic MS?

Output: AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the risk of thromboembolic events in patients with rheumatic MS?. ### Response: AF.


Instruction: A shortened diastolic filling interval with AF and a rapid ventricular response further increase what?

Output: LV pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A shortened diastolic filling interval with AF and a rapid ventricular response further increase what?. ### Response: LV pressure.


Instruction: What increases LV pressure?

Output: ventricular response

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases LV pressure?. ### Response: ventricular response.


Instruction: What is associated with worse outcomes in patients with rheumatic MS and with subop-timal results after PMBC?

Output: the presence of AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with worse outcomes in patients with rheumatic MS and with subop-timal results after PMBC?. ### Response: the presence of AF.


Instruction: What is beneficial in restoring normal sinus rhythm?

Output: lowering a high LA pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial in restoring normal sinus rhythm?. ### Response: lowering a high LA pressure.


Instruction: There is no randomized trial to prove the effectiveness of intervening early.

Output: tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no randomized trial to prove the effectiveness of intervening early.. ### Response: tension.


Instruction: What is a documented improve-ment in after PMBC?

Output: P-wave dispersion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a documented improve-ment in after PMBC?. ### Response: P-wave dispersion.


Instruction: Some patients have symptoms from what even with a mitral valve?

Output: higher LA pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some patients have symptoms from what even with a mitral valve?. ### Response: higher LA pressure.


Instruction: Patients with rheumatic MS have symptoms even with a mitral valve area >1.5 cm2 and a resting mean transmitral gradient 10 mm Hg?

Output: exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with rheumatic MS have symptoms even with a mitral valve area >1.5 cm2 and a resting mean transmitral gradient 10 mm Hg?. ### Response: exercise.


Instruction: What may be related to the variability and reliability of measuring a Mitral Valve area by planim-etering a short-axis image of the mitral?

Output: a resting mean transmitral gradient <10 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be related to the variability and reliability of measuring a Mitral Valve area by planim-etering a short-axis image of the mitral?. ### Response: a resting mean transmitral gradient <10 mm Hg.


Instruction: What can be used for indirect calculation of the mitral valve area?

Output: diastolic half-time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used for indirect calculation of the mitral valve area?. ### Response: diastolic half-time.


Instruction: What can patients who have a relatively low gradient at rest generate a much higher gradient with?

Output: exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can patients who have a relatively low gradient at rest generate a much higher gradient with?. ### Response: exercise.


Instruction: What is useful in patients who have a discrepancy between clinical symptoms and resting hemodynamics?

Output: exercise testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful in patients who have a discrepancy between clinical symptoms and resting hemodynamics?. ### Response: exercise testing.


Instruction: What can exercise testing be used for?

Output: clinical symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can exercise testing be used for?. ### Response: clinical symptoms.


Instruction: What is useful?

Output: pulmonary artery wedge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful?. ### Response: pulmonary artery wedge.


Instruction: Patients who increase their gradients to >15 mm Hg with exercise have been shown to improve symptomatically after what?

Output: PMBC.166

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients who increase their gradients to >15 mm Hg with exercise have been shown to improve symptomatically after what?. ### Response: PMBC.166.


Instruction: Both anatomic valve morphology and the presence of what predict suc-cessful PMBC?

Output: commissural calcification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Both anatomic valve morphology and the presence of what predict suc-cessful PMBC?. ### Response: commissural calcification.


Instruction: What percentage of patients with an anatomic valve Wilkins morphol-ogy score >822,23,31,32 have an optimal outcome?

Output: 42%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with an anatomic valve Wilkins morphol-ogy score >822,23,31,32 have an optimal outcome?. ### Response: 42%.


Instruction: What percentage increase in mitral valve area to >1.5 cm2?

Output: 25%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage increase in mitral valve area to >1.5 cm2?. ### Response: 25%.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227.


Instruction: What is a noninvasive evaluation of mitral regurgitation by analysis of left atrial signal loss in cine magnetic resonance?

Output: Pflugfelder PW, Sechtem UP , White RD, et al. Noninvasive evaluation of mitral regurgitation by analysis of left atrial signal loss in cine magnetic resonance. Am Heart J. 1989;117:1113–9. 8. Myerson SG, d’Arcy J, Christiansen JP , et al. Determination of clinical outcome in mitral regurgitation with cardiovascular magnetic resonance quantification. Circulation. 2016;133:2287–96. 9. Zoghbi WA, Adams D, Bonow RO, et al. Recommendations for noninvasive evaluation of native valvular regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a noninvasive evaluation of mitral regurgitation by analysis of left atrial signal loss in cine magnetic resonance?. ### Response: Pflugfelder PW, Sechtem UP , White RD, et al. Noninvasive evaluation of mitral regurgitation by analysis of left atrial signal loss in cine magnetic resonance. Am Heart J. 1989;117:1113–9. 8. Myerson SG, d’Arcy J, Christiansen JP , et al. Determination of clinical outcome in mitral regurgitation with cardiovascular magnetic resonance quantification. Circulation. 2016;133:2287–96. 9. Zoghbi WA, Adams D, Bonow RO, et al. Recommendations for noninvasive evaluation of native valvular regurgitation.


Instruction: What is the name of the technique used to analyze left atrial signal loss?

Output: cine magnetic resonance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the technique used to analyze left atrial signal loss?. ### Response: cine magnetic resonance.


Instruction: What is one of the results of the cine magnetic resonance analysis?

Output: Determination of clinical outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the results of the cine magnetic resonance analysis?. ### Response: Determination of clinical outcome.


Instruction: How is clinical outcome measured in mitral regurgitation?

Output: cardiovascular magnetic resonance quantification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is clinical outcome measured in mitral regurgitation?. ### Response: cardiovascular magnetic resonance quantification.


Instruction: Who developed the recommendations for noninvasive evaluation of native valvular regurgitation?

Output: American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed the recommendations for noninvasive evaluation of native valvular regurgitation?. ### Response: American Society of Echocardiography.


Instruction: What was developed in collaboration with the Society for Cardio-vascular Magnetic Resonance?

Output: Recommendations for noninvasive evaluation of native valvular regurgitation: a report from the American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed in collaboration with the Society for Cardio-vascular Magnetic Resonance?. ### Response: Recommendations for noninvasive evaluation of native valvular regurgitation: a report from the American Society of Echocardiography.


Instruction: What type of echocardiogra-phy is used in intraoperative evaluation of recon-struction of the atrioventricular valves?

Output: transesophageal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of echocardiogra-phy is used in intraoperative evaluation of recon-struction of the atrioventricular valves?. ### Response: transesophageal.


Instruction: What year did Thorac Cardiovasc Surg issue 35(Spec No. 2):140–2?

Output: 1987

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Thorac Cardiovasc Surg issue 35(Spec No. 2):140–2?. ### Response: 1987.


Instruction: How does TEE predict early and late postoperative mitral valve dys-function?

Output: Intraoperative TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does TEE predict early and late postoperative mitral valve dys-function?. ### Response: Intraoperative TEE.


Instruction: What predicts early and late postoperative mitral valve dys-function?

Output: Intraoperative TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts early and late postoperative mitral valve dys-function?. ### Response: Intraoperative TEE.


Instruction: What is part 2 of European Association of Echocar -diography recommendations for the assessment of valvular regurgitation?

Output: mitral and tricuspid regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is part 2 of European Association of Echocar -diography recommendations for the assessment of valvular regurgitation?. ### Response: mitral and tricuspid regurgitation.


Instruction: What is regurgitation?

Output: native valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is regurgitation?. ### Response: native valve disease.


Instruction: When did Eur J Echo-cardiogr. 2010 issue 11:307-32?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Echo-cardiogr. 2010 issue 11:307-32?. ### Response: 2010.


Instruction: What is the name of the disease that causes native valve disease?

Output: mitral and tricuspid regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes native valve disease?. ### Response: mitral and tricuspid regurgitation.


Instruction: Who was the author of Valvular heart disease in 1997?

Output: Carabello BA, Crawford FA Jr

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of Valvular heart disease in 1997?. ### Response: Carabello BA, Crawford FA Jr.


Instruction: In what year was N Engl J Med published?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was N Engl J Med published?. ### Response: 1997.


Instruction: What is the rationale for optimizing surgical indications?

Output: Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rationale for optimizing surgical indications?. ### Response: Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation.


Instruction: When did Circulation. 1999:400–5?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 1999:400–5?. ### Response: 1999.


Instruction: What should patients with severe degenerative mitral regurgitation delay surgery until symptoms develop?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with severe degenerative mitral regurgitation delay surgery until symptoms develop?. ### Response: 15.


Instruction: What did Schaff HV, AJ, Schuler G, Peterson KL, Johnson A, et al. do after surgical correction of organic mitral regurgitation?

Output: Impact of preoperative symptoms on survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Schaff HV, AJ, Schuler G, Peterson KL, Johnson A, et al. do after surgical correction of organic mitral regurgitation?. ### Response: Impact of preoperative symptoms on survival.


Instruction: What was the temporal response of left ventricular performance to mitral valve surgery?

Output: dys-function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the temporal response of left ventricular performance to mitral valve surgery?. ### Response: dys-function.


Instruction: What is standardization of adult transthoracic echocardiography reporting in agreement with recent chamber quantification, diastolic function, and heart valve disease recommendations?

Output: an expert con-sensus document of the European Association of Cardiovascular Imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is standardization of adult transthoracic echocardiography reporting in agreement with recent chamber quantification, diastolic function, and heart valve disease recommendations?. ### Response: an expert con-sensus document of the European Association of Cardiovascular Imaging.


Instruction: What is an expert con-senus document of the European Association of Cardiovascular Imaging?

Output: Standardization of adult transthoracic echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an expert con-senus document of the European Association of Cardiovascular Imaging?. ### Response: Standardization of adult transthoracic echocardiography.


Instruction: What is the most recent issue of Heart J Cardiovasc Imaging?

Output: Eur

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most recent issue of Heart J Cardiovasc Imaging?. ### Response: Eur.


Instruction: What are the names of the authors of the study?

Output: Dahm M, Iversen S, Schmid FX

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the study?. ### Response: Dahm M, Iversen S, Schmid FX.


Instruction: How does contrast enhancement and image quality affect two- and three-dimensional echocardiographic determi-cations?

Output: Jenner J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does contrast enhancement and image quality affect two- and three-dimensional echocardiographic determi-cations?. ### Response: Jenner J.


Instruction: Who published the 2019 Guidelines for Management of AIS e3732?

Output: Powers et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 Guidelines for Management of AIS e3732?. ### Response: Powers et al.


Instruction: What is recommended as noninferior to stent retriever for patients who meet all the following criteria?

Output: Direct aspiration thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended as noninferior to stent retriever for patients who meet all the following criteria?. ### Response: Direct aspiration thrombectomy.


Instruction: What is the NIHSS score of 6?

Output: ≥6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NIHSS score of 6?. ### Response: ≥6.


Instruction: What is a groin puncture?

Output: treatment initiation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a groin puncture?. ### Response: treatment initiation.


Instruction: When was the B-RRecommendation revised?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the B-RRecommendation revised?. ### Response: 2015.


Instruction: What year did endovascular.comparative available randomized data assess patients primarily in the therapeutic window within 6 hours of onset?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did endovascular.comparative available randomized data assess patients primarily in the therapeutic window within 6 hours of onset?. ### Response: 2015.


Instruction: What was the name of the COMPASS trial?

Output: Comparison of Direct Aspiration Versus Stent Retriever as a First Approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the COMPASS trial?. ### Response: Comparison of Direct Aspiration Versus Stent Retriever as a First Approach.


Instruction: How was the prestroke mRS score scored?

Output: 0 to 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the prestroke mRS score scored?. ### Response: 0 to 1.


Instruction: How many hours after symptom onset can treatment be initiated?

Output: 6 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours after symptom onset can treatment be initiated?. ### Response: 6 hours.


Instruction: What is the primary outcome of a groin puncture?

Output: noninferiority of mRS score at 90 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary outcome of a groin puncture?. ### Response: noninferiority of mRS score at 90 days.


Instruction: What is the first-line technique for stentriever thrombectomy?

Output: Direct aspiration thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first-line technique for stentriever thrombectomy?. ### Response: Direct aspiration thrombectomy.


Instruction: What was the primary outcome at 90 days?

Output: noninferiority of mRS score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome at 90 days?. ### Response: noninferiority of mRS score.


Instruction: How many patients in the aspiration group had an mRS score of 0 to 2?

Output: 69 of 134

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients in the aspiration group had an mRS score of 0 to 2?. ### Response: 69 of 134.


Instruction: What percentage of patients in the stentriever group showed noninferiority of aspiration thrombectomy?

Output: 50%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in the stentriever group showed noninferiority of aspiration thrombectomy?. ### Response: 50%).


Instruction: What was found to be no difference in recanalization rates or intracranial hemorrhage?

Output: aspiration thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to be no difference in recanalization rates or intracranial hemorrhage?. ### Response: aspiration thrombectomy.


Instruction: The ASTER trial compared what technique and standard stent retriever technique?

Output: contact aspiration technique

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ASTER trial compared what technique and standard stent retriever technique?. ### Response: contact aspiration technique.


Instruction: What was the first-line mechanical thrombectomy for successful revascularization within 6 hours among patients with acute anterior circulation ischemic stroke and LVO?

Output: Direct aspiration thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the first-line mechanical thrombectomy for successful revascularization within 6 hours among patients with acute anterior circulation ischemic stroke and LVO?. ### Response: Direct aspiration thrombectomy.


Instruction: What was different from COMPASS, lacking specification of NIHSS or ASPECTS?

Output: Eligibility criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was different from COMPASS, lacking specification of NIHSS or ASPECTS?. ### Response: Eligibility criteria.


Instruction: Primary outcome was what?

Output: successful revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Primary outcome was what?. ### Response: successful revascularization.


Instruction: What is the primary outcome of revascularization?

Output: successful revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary outcome of revascularization?. ### Response: successful revascularization.


Instruction: What was the percentage of patients with successful recovery at the end of all interventions in the contact aspiration group versus 83.1% in the stent retriever group?

Output: 85.4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the percentage of patients with successful recovery at the end of all interventions in the contact aspiration group versus 83.1% in the stent retriever group?. ### Response: 85.4%.


Instruction: The secondary outcome was what?

Output: 0 to 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The secondary outcome was what?. ### Response: 0 to 2.


Instruction: What was the primary clinical end point of mRS score at 90 days?

Output: noninferiority

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary clinical end point of mRS score at 90 days?. ### Response: noninferiority.


Instruction: What percentage of the contact aspiration group achieved the secondary clinical endpoint?

Output: 45.3%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the contact aspiration group achieved the secondary clinical endpoint?. ### Response: 45.3%).


Instruction: How much difference did the Penumbra Separator 3D Trial detect in the primary end point?

Output: 15%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much difference did the Penumbra Separator 3D Trial detect in the primary end point?. ### Response: 15%.


Instruction: What was the stent retriever group's OR?

Output: 1.20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the stent retriever group's OR?. ### Response: 1.20.


Instruction: What did some retrospective studies suggest about prophylaxis?

Output: therewas a benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some retrospective studies suggest about prophylaxis?. ### Response: therewas a benefit.


Instruction: What was the incubation period between a dentalprocedure and the onset of symptoms of IE?

Output: prolonged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the incubation period between a dentalprocedure and the onset of symptoms of IE?. ### Response: prolonged.


Instruction: Who published a study of dentalprocedures in the Netherlands and the efficacy of antibioticprophylaxis to prevent IE in patients with native or prostheticcardiac valves?

Output: van der Meer and colleagues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published a study of dentalprocedures in the Netherlands and the efficacy of antibioticprophylaxis to prevent IE in patients with native or prostheticcardiac valves?. ### Response: van der Meer and colleagues.


Instruction: What did der Meer and colleagues conclude that dental or other proce-dures caused only a small fraction of cases of?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did der Meer and colleagues conclude that dental or other proce-dures caused only a small fraction of cases of?. ### Response: IE.


Instruction: What would prevent only a small number of cases of IE if it were 100% effective?

Output: prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would prevent only a small number of cases of IE if it were 100% effective?. ### Response: prophylaxis.


Instruction: How long did the same authors perform a case-control study?

Output: 2-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the same authors perform a case-control study?. ### Response: 2-year.


Instruction: What percentage of patients for whom prophylaxis was recommended occurred despite receiving antibiotics?

Output: 5 of 20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients for whom prophylaxis was recommended occurred despite receiving antibiotics?. ### Response: 5 of 20.


Instruction: Who concluded that prophylaxis was not effective?

Output: The authors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who concluded that prophylaxis was not effective?. ### Response: The authors.


Instruction: In a separate study,87theseauthors reported poor awareness of what?

Output: recommendations for pro-phylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a separate study,87theseauthors reported poor awareness of what?. ### Response: recommendations for pro-phylaxis.


Instruction: What did Strom and colleagues2evaluate in a multicenter case-control study?

Output: dental prophylaxis andcardiac risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Strom and colleagues2evaluate in a multicenter case-control study?. ### Response: dental prophylaxis andcardiac risk factors.


Instruction: What are some of the risk factors for the development of IE?

Output: MVP, congenital heart disease (CHD),rheumatic heart disease (RHD), and previous cardiac valvesurgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the risk factors for the development of IE?. ### Response: MVP, congenital heart disease (CHD),rheumatic heart disease (RHD), and previous cardiac valvesurgery.


Instruction: What is another term for congenital heart disease?

Output: CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for congenital heart disease?. ### Response: CHD.


Instruction: How were control subjects with IE more likely to have had a dental procedure?

Output: with or without antibiotic prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were control subjects with IE more likely to have had a dental procedure?. ### Response: with or without antibiotic prophylaxis.


Instruction: Who concluded that dental treatment was not a risk factor for IE even in patients with valvularheart disease?

Output: The authors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who concluded that dental treatment was not a risk factor for IE even in patients with valvularheart disease?. ### Response: The authors.


Instruction: What could be prevented withprophylaxis even if it was 100% effective?

Output: few cases of IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be prevented withprophylaxis even if it was 100% effective?. ### Response: few cases of IE.


Instruction: What is the estimated risk of IE in adults with predisposing cardiac conditions who underwent dental procedures with or without antibiotic prophylaxis?

Output: 5 of 20 cases of IE occurred despitereceiving antibiotic prophylaxis. The authors concluded thatprophylaxis was not effective. In a separate study,87theseauthors reported poor awareness of recommendations for pro-phylaxis among both patients and healthcare providers.Strom and colleagues2evaluated dental prophylaxis andcardiac risk factors in a multicenter case-control study. Theseauthors reported that MVP, congenital heart disease (CHD),rheumatic heart disease (RHD), and previous cardiac valvesurgery were risk factors for the development of IE. In thatstudy, control subjects without IE were more likely to haveundergone a dental procedure than were those with cases ofIE (P/H110050.03

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the estimated risk of IE in adults with predisposing cardiac conditions who underwent dental procedures with or without antibiotic prophylaxis?. ### Response: 5 of 20 cases of IE occurred despitereceiving antibiotic prophylaxis. The authors concluded thatprophylaxis was not effective. In a separate study,87theseauthors reported poor awareness of recommendations for pro-phylaxis among both patients and healthcare providers.Strom and colleagues2evaluated dental prophylaxis andcardiac risk factors in a multicenter case-control study. Theseauthors reported that MVP, congenital heart disease (CHD),rheumatic heart disease (RHD), and previous cardiac valvesurgery were risk factors for the development of IE. In thatstudy, control subjects without IE were more likely to haveundergone a dental procedure than were those with cases ofIE (P/H110050.03.


Instruction: What did the authors of the study conclude would be necessary to prevent a very low number of cases?

Output: prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the authors of the study conclude would be necessary to prevent a very low number of cases?. ### Response: prophylaxis.


Instruction: What is the absolute risk of IE that results from a dental procedure?

Output: No published data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the absolute risk of IE that results from a dental procedure?. ### Response: No published data.


Instruction: What percentage of patients with IE caused by oral floraunderwent a preceding dental procedure within 30 or 180days of onset?

Output: 10% to 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with IE caused by oral floraunderwent a preceding dental procedure within 30 or 180days of onset?. ### Response: 10% to 20%.


Instruction: What is the term for a dental procedure within 30 or 180days of onset?

Output: preceding dental procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for a dental procedure within 30 or 180days of onset?. ### Response: preceding dental procedure.


Instruction: For how long have noted opinionleaders in medicine suggested a link between bacteremia-causing dental procedures and IE?

Output: 60 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For how long have noted opinionleaders in medicine suggested a link between bacteremia-causing dental procedures and IE?. ### Response: 60 years.


Instruction: Who suggested a link between bacteremia-causing dental procedures and IE?

Output: noted opinionleaders in medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who suggested a link between bacteremia-causing dental procedures and IE?. ### Response: noted opinionleaders in medicine.


Instruction: For how many years did theAHA publish regularly updated guidelines that emphasized the association between dental procedures with IE and recommended antibiotic prophylaxis?

Output: 50

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For how many years did theAHA publish regularly updated guidelines that emphasized the association between dental procedures with IE and recommended antibiotic prophylaxis?. ### Response: 50.


Instruction: What did the Framingham Offspring Cohort Study use to measure aCL from stored frozen sera?

Output: an ELISA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Framingham Offspring Cohort Study use to measure aCL from stored frozen sera?. ### Response: an ELISA.


Instruction: What was found to be associated with ischemic stroke or TIA in this study?

Output: aCL titers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to be associated with ischemic stroke or TIA in this study?. ### Response: aCL titers.


Instruction: What may be found in isch-emic stroke patients?

Output: elevated aCL titers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be found in isch-emic stroke patients?. ### Response: elevated aCL titers.


Instruction: What is the strength of the association between elevated aCL titers and stroke origin or risk?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strength of the association between elevated aCL titers and stroke origin or risk?. ### Response: uncertain.


Instruction: What is the aCL ELISA?

Output: a test with low sensitivity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the aCL ELISA?. ### Response: a test with low sensitivity.


Instruction: What is a cofactor for antiphospho-lipid binding?

Output: anti-β2GPI antibodies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cofactor for antiphospho-lipid binding?. ### Response: anti-β2GPI antibodies.


Instruction: How many studies have investigated 2GPI?

Output: Only a few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have investigated 2GPI?. ### Response: Only a few.


Instruction: How many studies have investigated 2GPI in the absence of SLE?

Output: Only a few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have investigated 2GPI in the absence of SLE?. ### Response: Only a few.


Instruction: What is difficult to establish as an independent risk factor?

Output: anti-β2GPI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is difficult to establish as an independent risk factor?. ### Response: anti-β2GPI.


Instruction: What does significance of these antibodies require further investigation?

Output: clinical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does significance of these antibodies require further investigation?. ### Response: clinical.


Instruction: What was performed to establish the incidence of first-time thromboembolic events in subjects with a high-risk aPL profile?

Output: A prospective, observational study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was performed to establish the incidence of first-time thromboembolic events in subjects with a high-risk aPL profile?. ### Response: A prospective, observational study.


Instruction: How much was the annual rate of first thromboembolus?

Output: 1.9%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the annual rate of first thromboembolus?. ### Response: 1.9%.


Instruction: What was the annual rate of thromboembolus?

Output: 1.9%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the annual rate of thromboembolus?. ### Response: 1.9%.


Instruction: How much of the thromb-embolic events were stroke or TIA?

Output: Forty percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the thromb-embolic events were stroke or TIA?. ### Response: Forty percent.


Instruction: Aspirin did not affect the incidence of what?

Output: Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin did not affect the incidence of what?. ### Response: Stroke.


Instruction: What does not affect the incidence of stroke?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not affect the incidence of stroke?. ### Response: aspirin.


Instruction: How many mg of aspirin every other day did not protect against venous throm-boembolism in the Physicians’ Health Study?

Output: 325

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg of aspirin every other day did not protect against venous throm-boembolism in the Physicians’ Health Study?. ### Response: 325.


Instruction: What did not protect against venous throm-boembolism in 40-84-year-old men with moderate to high aCL titers?

Output: 325 mg aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not protect against venous throm-boembolism in 40-84-year-old men with moderate to high aCL titers?. ### Response: 325 mg aspirin.


Instruction: What is an ongoing primary prevention trial of warfarin therapy to decrease thromboembolic events?

Output: INR, 2.0–2.5) to decrease thromboembolic events in patients with lupus and aPL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ongoing primary prevention trial of warfarin therapy to decrease thromboembolic events?. ### Response: INR, 2.0–2.5) to decrease thromboembolic events in patients with lupus and aPL.


Instruction: What was the name of the small, multicenter, double-blind, pla-cebo-controlled trial for the primary prevention of thrombosis in asymptomatic patients who were persistently aPL positive?

Output: Antiphospholipid Antibody Acetylsalicylic Acid (APLASA)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the small, multicenter, double-blind, pla-cebo-controlled trial for the primary prevention of thrombosis in asymptomatic patients who were persistently aPL positive?. ### Response: Antiphospholipid Antibody Acetylsalicylic Acid (APLASA).


Instruction: How long did the average follow-up of the APLASA study last?

Output: 2.30±0.95 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the average follow-up of the APLASA study last?. ### Response: 2.30±0.95 years.


Instruction: How long was the average follow-up?

Output: 2.30±0.95 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the average follow-up?. ### Response: 2.30±0.95 years.


Instruction: What were the rates of acute thrombosis for aspirin-treated subjects?

Output: 2.75 per 100 patient-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the rates of acute thrombosis for aspirin-treated subjects?. ### Response: 2.75 per 100 patient-years.


Instruction: How was the sample size?

Output: relatively small

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the sample size?. ### Response: relatively small.


Instruction: Why was the study insufficiently powered?

Output: The sample size was relatively small

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the study insufficiently powered?. ### Response: The sample size was relatively small.


Instruction: A parallel and separate observational study published within the APLASA study found no reduction in what?

Output: the rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A parallel and separate observational study published within the APLASA study found no reduction in what?. ### Response: the rate.


Instruction: What is the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction?

Output: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction?. ### Response: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.


Instruction: How is ST-elevation myocardial infarction managed?

Output: ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is ST-elevation myocardial infarction managed?. ### Response: ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.


Instruction: What is the name of the Task Force on Practice Guidelines?

Output: American College of Cardiology Foundation/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Practice Guidelines?. ### Response: American College of Cardiology Foundation/American Heart Association.


Instruction: When was this article published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: 2012.


Instruction: Where is this document available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is this document available?. ### Response: http://ahajournals.org.


Instruction: What is the American College of Cardiology's website?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the American College of Cardiology's website?. ### Response: www.cardiosource.org.


Instruction: Where is a copy of the document available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is a copy of the document available?. ### Response: http://ahajournals.org.


Instruction: What is another name for the American Heart Association?

Output: my.americanheart.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the American Heart Association?. ### Response: my.americanheart.org.


Instruction: Where is peer review of AHA Scientific Statements conducted?

Output: AHA National Center

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is peer review of AHA Scientific Statements conducted?. ### Response: AHA National Center.


Instruction: Where can you find more information on AHA statements and guidelines development?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find more information on AHA statements and guidelines development?. ### Response: http://my.americanheart.org/statements.


Instruction: What is the name of the link to purchase additional AHA reprints?

Output: 843-216-2533

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the link to purchase additional AHA reprints?. ### Response: 843-216-2533.


Instruction: What is not permitted without the express permission of the American Heart Association?

Output: Multiple copies, modification, alteration, enhancement, and/or distribution of this document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not permitted without the express permission of the American Heart Association?. ### Response: Multiple copies, modification, alteration, enhancement, and/or distribution of this document.


Instruction: Where are instructions for obtaining permission located?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are instructions for obtaining permission located?. ### Response: http://www.heart.org.


Instruction: What appears on the right side of the page?

Output: A link to the “Copyright Permissions Request Form

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What appears on the right side of the page?. ### Response: A link to the “Copyright Permissions Request Form.


Instruction: On which side of the page?

Output: right

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On which side of the page?. ### Response: right.


Instruction: What is the name of the organization that created this publication?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that created this publication?. ### Response: American Heart Association.


Instruction: When was this publication released?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication released?. ### Response: 2012.


Instruction: What is End-Stage Renal Disease?

Output: Renal failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is End-Stage Renal Disease?. ### Response: Renal failure.


Instruction: Where is NIH Publication No. 09-3176.1213.

Output: Bethesda, Md: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is NIH Publication No. 09-3176.1213.. ### Response: Bethesda, Md: 2009.


Instruction: What pre-disposes patients to adverse outcome after coronary artery bypasssurgery?

Output: Renal failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What pre-disposes patients to adverse outcome after coronary artery bypasssurgery?. ### Response: Renal failure.


Instruction: What is the VA Cooperative Study #5?

Output: Renal failure pre-disposes patients to adverse outcome after coronary artery bypasssurgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA Cooperative Study #5?. ### Response: Renal failure pre-disposes patients to adverse outcome after coronary artery bypasssurgery.


Instruction: What is the impact of renal dys-function on outcomes of coronary artery bypass surgery?

Output: results fromthe Society of Thoracic Surgeons National Adult Cardiac Database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of renal dys-function on outcomes of coronary artery bypass surgery?. ### Response: results fromthe Society of Thoracic Surgeons National Adult Cardiac Database.


Instruction: What are the results from the Society of Thoracic Surgeons National Adult Cardiac Database?

Output: Impact of renal dys-function on outcomes of coronary artery bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results from the Society of Thoracic Surgeons National Adult Cardiac Database?. ### Response: Impact of renal dys-function on outcomes of coronary artery bypass surgery.


Instruction: What is the name of the procedure used for long-term survival after coronary artery bypass graft surgery?

Output: mitral valve restrictive annuloplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used for long-term survival after coronary artery bypass graft surgery?. ### Response: mitral valve restrictive annuloplasty.


Instruction: What is one of the outcomes of patients withchronic renal insufficiency in the bypass angioplasty revascularizationinvestigation?

Output: Survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the outcomes of patients withchronic renal insufficiency in the bypass angioplasty revascularizationinvestigation?. ### Response: Survival.


Instruction: What is mild to moderate aortic stenosis at the time of coronary artery bypass grafting?

Output: Management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is mild to moderate aortic stenosis at the time of coronary artery bypass grafting?. ### Response: Management.


Instruction: What is a decisionanalysis approach to the surgical procedure?

Output: Should coronaryartery bypass graft surgery patients with mild or moderate aorticstenosis undergo concomitant aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a decisionanalysis approach to the surgical procedure?. ### Response: Should coronaryartery bypass graft surgery patients with mild or moderate aorticstenosis undergo concomitant aortic valve replacement.


Instruction: What is a decisionanalysis approach to the surgical dilemma?

Output: Should coronaryartery bypass graft surgery patients with mild or moderate aorticstenosis undergo concomitant aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a decisionanalysis approach to the surgical dilemma?. ### Response: Should coronaryartery bypass graft surgery patients with mild or moderate aorticstenosis undergo concomitant aortic valve replacement.


Instruction: When is concomitant aortic valve replacement indicated?

Output: after isolated coronary artery bypassgrafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is concomitant aortic valve replacement indicated?. ### Response: after isolated coronary artery bypassgrafting.


Instruction: What type of valve replacement is indicated in patients with mild to moderate stenosisundergoing coronary revascularization?

Output: concomitant aortic valvereplacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve replacement is indicated in patients with mild to moderate stenosisundergoing coronary revascularization?. ### Response: concomitant aortic valvereplacement.


Instruction: What year did Curr Cardiol Rep.7:101–4.1221.

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Curr Cardiol Rep.7:101–4.1221.. ### Response: 2005.


Instruction: What is repair preferable to for ischemic mitral regurgitation?

Output: toreplacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is repair preferable to for ischemic mitral regurgitation?. ### Response: toreplacement.


Instruction: What is the name of the procedure that corrects moderate ischemic mitral regurgitation?

Output: coronary artery bypassgrafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure that corrects moderate ischemic mitral regurgitation?. ### Response: coronary artery bypassgrafting.


Instruction: What are the names of the procedures that correct moderate ischemia?

Output: coronary artery bypassgrafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the procedures that correct moderate ischemia?. ### Response: coronary artery bypassgrafting.


Instruction: How is survival after coronaryrevascularization measured?

Output: with and without mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is survival after coronaryrevascularization measured?. ### Response: with and without mitral valve surgery.


Instruction: In patients with moderate ischemic mitral valveregurgitation, what is a randomized trial?

Output: efficacy ofadding mitral valve restrictive annuloplasty to coronary arterybypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with moderate ischemic mitral valveregurgitation, what is a randomized trial?. ### Response: efficacy ofadding mitral valve restrictive annuloplasty to coronary arterybypass grafting.


Instruction: What is the name of the study that evaluated the efficacy of adding a restrictive annuloplasty to coronary artery bypass grafting?

Output: a randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the efficacy of adding a restrictive annuloplasty to coronary artery bypass grafting?. ### Response: a randomized trial.


Instruction: In what year was the J Thorac Cardiovasc Surg published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the J Thorac Cardiovasc Surg published?. ### Response: 2009.


Instruction: What is the name of the procedure that results in moderateischemic mitral regurgitation?

Output: isolated coronary artery bypassgrafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure that results in moderateischemic mitral regurgitation?. ### Response: isolated coronary artery bypassgrafting.


Instruction: How many patients were treated with isolated coronary artery bypassgrafting in 2010?

Output: 90:1187

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with isolated coronary artery bypassgrafting in 2010?. ### Response: 90:1187.


Instruction: What is one of the recommendations for the evaluation of the severity of NativeValvular Regurgitation with Two-dimensional and Doppler Echocardiography?

Output: Zoghbi W, Sarano M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the recommendations for the evaluation of the severity of NativeValvular Regurgitation with Two-dimensional and Doppler Echocardiography?. ### Response: Zoghbi W, Sarano M.


Instruction: What is the name of the department that performs echocardiography?

Output: J Am Soc of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the department that performs echocardiography?. ### Response: J Am Soc of Echocardiography.


Instruction: When did the J Am Soc of Echocardiography issue 16:777–802.1227?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Soc of Echocardiography issue 16:777–802.1227?. ### Response: 2003.


Instruction: What type of angina is returned after coronary intervention?

Output: ischemic mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of angina is returned after coronary intervention?. ### Response: ischemic mitral.


Instruction: What is routine cholesterol surveillance in child-hood?

Output: Lipid screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is routine cholesterol surveillance in child-hood?. ### Response: Lipid screening.


Instruction: What is the name of the screening for familial hypercholes-terolemia?

Output: Statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the screening for familial hypercholes-terolemia?. ### Response: Statins.


Instruction: What year did Pathology 44:122–8 appear?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Pathology 44:122–8 appear?. ### Response: 2012.


Instruction: What is the name of the National Institute for Health and Care Excellence (UK)?

Output: NICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the National Institute for Health and Care Excellence (UK)?. ### Response: NICE.


Instruction: Where is Familial hypercholesterolaemia: identification and management available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Familial hypercholesterolaemia: identification and management available?. ### Response: http://www.nice.org.uk/guidance/CG71.


Instruction: When was dyslipidemia and blood pressure among US children and adoles-cents?

Output: 1999–2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was dyslipidemia and blood pressure among US children and adoles-cents?. ### Response: 1999–2012.


Instruction: Blood pressure among US children and adoles-cents, 1999-2012 JAMA Pediatr. 2015;169:272-9. S4.4.4.3-26. May AL, Kuklina EV, Yoon PW, et al. Prevalence of cardiovascular dis-ease risk factors among US adolescents. 1999-2008 Pediatrics. 2012;129:1035-41. What did Lozano P, Henrikson NB, Morrison CC, and Morrison C do?

Output: dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood pressure among US children and adoles-cents, 1999-2012 JAMA Pediatr. 2015;169:272-9. S4.4.4.3-26. May AL, Kuklina EV, Yoon PW, et al. Prevalence of cardiovascular dis-ease risk factors among US adolescents. 1999-2008 Pediatrics. 2012;129:1035-41. What did Lozano P, Henrikson NB, Morrison CC, and Morrison C do?. ### Response: dyslipidemia.


Instruction: What did the US Preventive Services Task Force use to detect multifactorial dys-lipidemia?

Output: Lipid screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the US Preventive Services Task Force use to detect multifactorial dys-lipidemia?. ### Response: Lipid screening.


Instruction: What is the name of the scientific statement from the American Heart Association?

Output: The agenda for familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the scientific statement from the American Heart Association?. ### Response: The agenda for familial hypercholesterolemia.


Instruction: What is the name of the scientific statement released by the American Heart Association?

Output: The agenda for familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the scientific statement released by the American Heart Association?. ### Response: The agenda for familial hypercholesterolemia.


Instruction: What is a lipid screening in child-hood and adolescence for?

Output: detection of multifactorial dys-lipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a lipid screening in child-hood and adolescence for?. ### Response: detection of multifactorial dys-lipidemia.


Instruction: What is atorvas-tatin used for in children with lupus erythematosus?

Output: reduce atherosclerosis pro-gression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atorvas-tatin used for in children with lupus erythematosus?. ### Response: reduce atherosclerosis pro-gression.


Instruction: What is Ardoin used for?

Output: Secondary analysis of APPLE study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Ardoin used for?. ### Response: Secondary analysis of APPLE study.


Instruction: What is erythematosus in children and adolescents?

Output: systemic lupus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is erythematosus in children and adolescents?. ### Response: systemic lupus.


Instruction: Arthritis Rheum. 2012;64:285–96. S4.4.4.3-32.

Output: 2016;316:634–44

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arthritis Rheum. 2012;64:285–96. S4.4.4.3-32.. ### Response: 2016;316:634–44.


Instruction: What may reduce atherosclerosis pro-gression in pubertal lupus patients with higher C reactive protein?

Output: atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may reduce atherosclerosis pro-gression in pubertal lupus patients with higher C reactive protein?. ### Response: atorvastatin.


Instruction: What is the phenotype of ath-erosclerotic cardiovascular disease in US adults with familial hypercholesterolemia?

Output: Long-term risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the phenotype of ath-erosclerotic cardiovascular disease in US adults with familial hypercholesterolemia?. ### Response: Long-term risk.


Instruction: What is a risk factor for non-coronary heart disease mortality and cancer in patients with treated heart disease?

Output: familial hypercholesterolaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for non-coronary heart disease mortality and cancer in patients with treated heart disease?. ### Response: familial hypercholesterolaemia.


Instruction: What is the risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia?

Output: Non-coronary heart disease mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia?. ### Response: Non-coronary heart disease mortality.


Instruction: What was the name of the prospective regis-try study?

Output: Non-coronary heart disease mortality and risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the prospective regis-try study?. ### Response: Non-coronary heart disease mortality and risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia.


Instruction: When was the Atherosclerosis.179:293–7?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Atherosclerosis.179:293–7?. ### Response: 2005.


Instruction: What year was the 63rd issue of the journal 63:1935-47?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the 63rd issue of the journal 63:1935-47?. ### Response: 2014.


Instruction: What is the name of the study that focuses on cholesterol screening?

Output: S4.4.4.3-21

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that focuses on cholesterol screening?. ### Response: S4.4.4.3-21.


Instruction: What is lower estimated glomerularfiltration rate and higher albuminuria associated with?

Output: all-cause and cardiovascular mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lower estimated glomerularfiltration rate and higher albuminuria associated with?. ### Response: all-cause and cardiovascular mortality.


Instruction: What is a collaborative meta-analysis of kidney diseasepopulation cohorts?

Output: Lower estimated glomerularﬁltration rate and higher albuminuria are associated with mortality andend-stage renal disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a collaborative meta-analysis of kidney diseasepopulation cohorts?. ### Response: Lower estimated glomerularﬁltration rate and higher albuminuria are associated with mortality andend-stage renal disease.


Instruction: Kidney Int 2011; 79: 1331–1340.17

Output: 16. Astor BC, Matsushita K, Gansevoort RT et al. Lower estimated glomerularﬁltration rate and higher albuminuria are associated with mortality andend-stage renal disease. A collaborative meta-analysis of kidney diseasepopulation cohorts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kidney Int 2011; 79: 1331–1340.17. ### Response: 16. Astor BC, Matsushita K, Gansevoort RT et al. Lower estimated glomerularﬁltration rate and higher albuminuria are associated with mortality andend-stage renal disease. A collaborative meta-analysis of kidney diseasepopulation cohorts.


Instruction: What are lower estimated GFR and higher albuminuria associated with?

Output: adverse kidney outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are lower estimated GFR and higher albuminuria associated with?. ### Response: adverse kidney outcomes.


Instruction: What is the association between estimated glomerular filtration rate and albumineuria?

Output: all-cause and cardiovas-cular mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between estimated glomerular filtration rate and albumineuria?. ### Response: all-cause and cardiovas-cular mortality.


Instruction: A collaborative meta-analysis of general and high-risk population cohorts.

Output: Kidney Int

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A collaborative meta-analysis of general and high-risk population cohorts.. ### Response: Kidney Int.


Instruction: What is the association of estimatedglomerular filtration rate and albuminuria with all-cause and cardiovas-cular mortality in general population cohorts?

Output: a collaborative meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of estimatedglomerular filtration rate and albuminuria with all-cause and cardiovas-cular mortality in general population cohorts?. ### Response: a collaborative meta-analysis.


Instruction: What is a collaborative meta-analysis?

Output: kidney diseasepopulation cohorts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a collaborative meta-analysis?. ### Response: kidney diseasepopulation cohorts.


Instruction: What is albuminuria associated with?

Output: all-cause and cardiovas-cular mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is albuminuria associated with?. ### Response: all-cause and cardiovas-cular mortality.


Instruction: What is a collaborative meta-analysis ofhigh-risk population cohorts?

Output: Kidney Int

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a collaborative meta-analysis ofhigh-risk population cohorts?. ### Response: Kidney Int.


Instruction: How many years ago was Kidney Int 79: 1341– 1352.20?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years ago was Kidney Int 79: 1341– 1352.20?. ### Response: 2011.


Instruction: What is the age-specific relevance of usualblood pressure to vascular mortality?

Output: a meta-analysis of individual datafor one million adults in 61 prospective studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age-specific relevance of usualblood pressure to vascular mortality?. ### Response: a meta-analysis of individual datafor one million adults in 61 prospective studies.


Instruction: How many prospective studies were conducted in 2002?

Output: 61

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prospective studies were conducted in 2002?. ### Response: 61.


Instruction: What is the effect of stopping inhibitors of the renin-angiotensin system in patients with advanced chronic kidney disease?

Output: mortality reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of stopping inhibitors of the renin-angiotensin system in patients with advanced chronic kidney disease?. ### Response: mortality reduction.


Instruction: When did Ahmed AK, Kamath NS, El Kossi M et al. study the impact of stopping what?

Output: inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ahmed AK, Kamath NS, El Kossi M et al. study the impact of stopping what?. ### Response: inhibitor.


Instruction: What is chronic kidney disease associated with?

Output: coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is chronic kidney disease associated with?. ### Response: coronary heart disease.


Instruction: What is a reductaseinhibitor used for?

Output: mortality reduction in hemodialysispatients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reductaseinhibitor used for?. ### Response: mortality reduction in hemodialysispatients.


Instruction: What is HMG-coenzyme a reductaseinhibitor use associated with?

Output: mortality reduction in hemodialysispatients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HMG-coenzyme a reductaseinhibitor use associated with?. ### Response: mortality reduction in hemodialysispatients.


Instruction: What is associated with mortality reduction in hemodialysispatients?

Output: HMG-coenzyme a reductaseinhibitor use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with mortality reduction in hemodialysispatients?. ### Response: HMG-coenzyme a reductaseinhibitor use.


Instruction: Where did Fellstrom BC, Jardine AG, Schmieder RE et al. Rosuvastatin andcardiovascular events in patients undergo?

Output: hemodialysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did Fellstrom BC, Jardine AG, Schmieder RE et al. Rosuvastatin andcardiovascular events in patients undergo?. ### Response: hemodialysis.


Instruction: When did N Engl JMed 2009: 360: 1395-1407.27?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl JMed 2009: 360: 1395-1407.27?. ### Response: 2009.


Instruction: What is the name of the disease that causes diabetes mellitus?

Output: hemodialysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes diabetes mellitus?. ### Response: hemodialysis.


Instruction: What are the names of the patients who are undergoing hemodialysis?

Output: Wanner C, Krane V, Marz W et al. A t o r v a s t a t i ni np a t i e n t sw i t ht y p e2diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the patients who are undergoing hemodialysis?. ### Response: Wanner C, Krane V, Marz W et al. A t o r v a s t a t i ni np a t i e n t sw i t ht y p e2diabetes mellitus.


Instruction: When was the NE n g lJM published?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the NE n g lJM published?. ### Response: 2005.


Instruction: What is the name of the study that found that traditional and nontraditional risk factorspredict coronary heart disease in chronic kidney disease?

Output: theatherosclerosis risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that found that traditional and nontraditional risk factorspredict coronary heart disease in chronic kidney disease?. ### Response: theatherosclerosis risk.


Instruction: What are the results of the atherosclerosis risk in communities study?

Output: Traditional and nontraditional risk factorspredict coronary heart disease in chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the atherosclerosis risk in communities study?. ### Response: Traditional and nontraditional risk factorspredict coronary heart disease in chronic kidney disease.


Instruction: What is the systolic blood pressure and death risk in hemodialysis patients?

Output: epidemiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic blood pressure and death risk in hemodialysis patients?. ### Response: epidemiology.


Instruction: What are the clinical practice guidelines and recommendations for diabetes and chronic kidney disease?

Output: KDOQI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinical practice guidelines and recommendations for diabetes and chronic kidney disease?. ### Response: KDOQI.


Instruction: What may be a reasonable guideline in some circumstances?

Output: Mission: Lifeline algorithm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be a reasonable guideline in some circumstances?. ### Response: Mission: Lifeline algorithm.


Instruction: What will be needed to account for local and regional factors?

Output: Customization of the guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will be needed to account for local and regional factors?. ### Response: Customization of the guideline.


Instruction: What is recommended for operationalized bypass algorithms?

Output: Rapid, protected, collaborative, regional quality review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for operationalized bypass algorithms?. ### Response: Rapid, protected, collaborative, regional quality review.


Instruction: Where is Table III in online Data Supplement 1?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Table III in online Data Supplement 1?. ### Response: http://ahajournals.org.


Instruction: What is the name of the online data supplement?

Output: Data Supplement 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the online data supplement?. ### Response: Data Supplement 1.


Instruction: When was the data supplement 1 downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the data supplement 1 downloaded?. ### Response: April 28, 2023.


Instruction: What language were systematic reviews limited to?

Output: English

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What language were systematic reviews limited to?. ### Response: English.


Instruction: What tool did we use to assess the quality of systematic reviews?

Output: Assessment of Multiple Systematic Reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tool did we use to assess the quality of systematic reviews?. ### Response: Assessment of Multiple Systematic Reviews.


Instruction: What tool was used to assess multiple systematic reviews?

Output: Assessment of Multiple Systematic Reviews tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tool was used to assess multiple systematic reviews?. ### Response: Assessment of Multiple Systematic Reviews tool.


Instruction: What did we use in the absence of a satisfactory systematic review?

Output: meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we use in the absence of a satisfactory systematic review?. ### Response: meta-analyses.