Instruction: Harenberg J. Pharmacology of low molecular weight hepa-rins?

Output: Semin Thromb Hemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Harenberg J. Pharmacology of low molecular weight hepa-rins?. ### Response: Semin Thromb Hemost.


Instruction: Semin Thromb Hemost. 1990 ; 16 (suppl ): 12 - 18.

Output: Semin Thromb Hemost  .  1990

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Semin Thromb Hemost. 1990 ; 16 (suppl ): 12 - 18.. ### Response: Semin Thromb Hemost  .  1990.


Instruction: Johnson EA, Kirkwood.

Output: TB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Johnson EA, Kirkwood.. ### Response: TB.


Instruction: How many heparin preparations did Johnson EA, Kirkwood TB, Stirling Y, et al. use after sub-cutaneous injection?

Output: Four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many heparin preparations did Johnson EA, Kirkwood TB, Stirling Y, et al. use after sub-cutaneous injection?. ### Response: Four.


Instruction: How many ( 3 ): 586 - Thromb Haemost?

Output: 35

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 3 ): 586 - Thromb Haemost?. ### Response: 35.


Instruction: How long is the half-life of argatroban in plasma?

Output: 45 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the half-life of argatroban in plasma?. ### Response: 45 min.


Instruction: How is it metabolized in the liver?

Output: via the cytochrome P450 3A4/5 enzyme system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is it metabolized in the liver?. ### Response: via the cytochrome P450 3A4/5 enzyme system.


Instruction: What is metabolized in the liver 226 via the cytochrome P450 3A4/5 enzyme system?

Output: argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is metabolized in the liver 226 via the cytochrome P450 3A4/5 enzyme system?. ### Response: argatroban.


Instruction: What must be used with caution in patients with hepatic dysfunction?

Output: argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be used with caution in patients with hepatic dysfunction?. ### Response: argatroban.


Instruction: Why is argatroban particu-larly useful?

Output: Because it is not renally excreted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is argatroban particu-larly useful?. ### Response: Because it is not renally excreted.


Instruction: What is Argatroban licensed for?

Output: treatment and preven-tion of HIT-associated thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Argatroban licensed for?. ### Response: treatment and preven-tion of HIT-associated thrombosis.


Instruction: What is contraindicated because of a recent history of HIT?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is contraindicated because of a recent history of HIT?. ### Response: heparin.


Instruction: What is the initial dose of a continuous IV infusion?

Output: 1 to 2  m g/kg/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the initial dose of a continuous IV infusion?. ### Response: 1 to 2  m g/kg/min.


Instruction: What is adjusted to maintain the aPTT ratio in the 1.5 to 2.5 range?

Output: Argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is adjusted to maintain the aPTT ratio in the 1.5 to 2.5 range?. ### Response: Argatroban.


Instruction: What is used to monitor therapy with direct thrombin inhibitors?

Output: aPTT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to monitor therapy with direct thrombin inhibitors?. ### Response: aPTT.


Instruction: The dose-response is not linear and the aPTT reaches a plateau with higher doses of the various drugs?

Output: direct thrombin inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The dose-response is not linear and the aPTT reaches a plateau with higher doses of the various drugs?. ### Response: direct thrombin inhibitors.


Instruction: What reagents vary in their sensitivities to direct thrombin inhibitors?

Output: aPTT reagents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reagents vary in their sensitivities to direct thrombin inhibitors?. ### Response: aPTT reagents.


Instruction: What yields a more linear dose-response?

Output: ecarin clotting time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What yields a more linear dose-response?. ### Response: ecarin clotting time.


Instruction: The ecarin clotting time is not widely available and has not been what?

Output: standardized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ecarin clotting time is not widely available and has not been what?. ### Response: standardized.


Instruction: What does vitamin K antagonists do to the INR?

Output: transition-ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does vitamin K antagonists do to the INR?. ### Response: transition-ing.


Instruction: What does argatroban have the greatest effect on when given in thera-peutic doses?

Output: the INR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does argatroban have the greatest effect on when given in thera-peutic doses?. ### Response: the INR.


Instruction: What can be measured after stopping the argatroban infusion for several hours?

Output: INR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be measured after stopping the argatroban infusion for several hours?. ### Response: INR.


Instruction: What is another option to monitor the vitamin K antagonist with a chromogenic factor X assay?

Output: argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another option to monitor the vitamin K antagonist with a chromogenic factor X assay?. ### Response: argatroban.


Instruction: What percentage of factor X levels have been associated with INR values?

Output: 45%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of factor X levels have been associated with INR values?. ### Response: 45%.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the name of the guideline that will be published in 2021?

Output: ACC/AHA Guideline for the Management of Valvular Heart Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline that will be published in 2021?. ### Response: ACC/AHA Guideline for the Management of Valvular Heart Disease.


Instruction: Where are the references to the recommendations summarized?

Output: Online Data Supplement 14.COR LOE Recommendations1 B-NR1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the references to the recommendations summarized?. ### Response: Online Data Supplement 14.COR LOE Recommendations1 B-NR1.


Instruction: Where are the recommendations summarized?

Output: Online Data Supplement 14.COR LOE Recommendations1 B-NR1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the recommendations summarized?. ### Response: Online Data Supplement 14.COR LOE Recommendations1 B-NR1.


Instruction: What is indicated in patients with signs or symptoms of AR?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated in patients with signs or symptoms of AR?. ### Response: TTE.


Instruction: What is indicated in patients with a BAV or with known dilation of the aortic sinuses?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated in patients with a BAV or with known dilation of the aortic sinuses?. ### Response: TTE.


Instruction: What is TTE indicated to evaluate the presence and severity of AR?

Output: In patients with a BAV or with known dilation of the aortic sinuses or ascending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TTE indicated to evaluate the presence and severity of AR?. ### Response: In patients with a BAV or with known dilation of the aortic sinuses or ascending aorta.


Instruction: In patients with moderate or severe AR, what is indicated?

Output: TEE, CMR, or cardiac catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with moderate or severe AR, what is indicated?. ### Response: TEE, CMR, or cardiac catheterization.


Instruction: What is indicated for the assessment of LV systolic function?

Output: TEE, CMR, or cardiac catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated for the assessment of LV systolic function?. ### Response: TEE, CMR, or cardiac catheterization.


Instruction: What provides diagnostic information about the etiology and mechanism of AR?

Output: SynopsisTTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides diagnostic information about the etiology and mechanism of AR?. ### Response: SynopsisTTE.


Instruction: What is the etiology and mechanism of AR?

Output: valve reparability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the etiology and mechanism of AR?. ### Response: valve reparability.


Instruction: What does imaging with TEE, CMR or aortic angiogra-phy provide when needed?

Output: additional information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does imaging with TEE, CMR or aortic angiogra-phy provide when needed?. ### Response: additional information.


Instruction: What are better predictors of clini-cal outcome when AR is signifi-cant?

Output: quantitative measures of regurgitant volume and effective regurgitant orifice (ERO) area1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are better predictors of clini-cal outcome when AR is signifi-cant?. ### Response: quantitative measures of regurgitant volume and effective regurgitant orifice (ERO) area1.


Instruction: What are measures of LV systolic function called?

Output: LVEF or fractional shortening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are measures of LV systolic function called?. ### Response: LVEF or fractional shortening.


Instruction: What is systolic function also known as?

Output: depressed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is systolic function also known as?. ### Response: depressed.


Instruction: What are predictive of the development of HF symptoms or death in asymptomatic patients?

Output: Measures of LV systolic function (LVEF or fractional shortening) and LV end-systolic dimension (LVESD) or LV end-systolic volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are predictive of the development of HF symptoms or death in asymptomatic patients?. ### Response: Measures of LV systolic function (LVEF or fractional shortening) and LV end-systolic dimension (LVESD) or LV end-systolic volume.


Instruction: What type of patients have a significantly better long-term postoperative survival rate than those with depressed systolic function?

Output: Symptomatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients have a significantly better long-term postoperative survival rate than those with depressed systolic function?. ### Response: Symptomatic.


Instruction: What has high specificity for detecting AR but low sensitivity and diagnostic accuracy?

Output: Auscultation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has high specificity for detecting AR but low sensitivity and diagnostic accuracy?. ### Response: Auscultation.


Instruction: What can TTE identify in patients who have been deemed to be at risk?

Output: AR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can TTE identify in patients who have been deemed to be at risk?. ### Response: AR.


Instruction: What is a condition associated with abnormal aortic valve function such as a BAV?

Output: aortic dilation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a condition associated with abnormal aortic valve function such as a BAV?. ### Response: aortic dilation.


Instruction: What is useful for evaluating patients in whom there is discordance between clinical assessment and severity of AR by TTE or when TTE images are suboptimal?

Output: TTE and CMR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful for evaluating patients in whom there is discordance between clinical assessment and severity of AR by TTE or when TTE images are suboptimal?. ### Response: TTE and CMR.


Instruction: What pro-vides accurate and reproducible measures of regurgitant volume and regurgitation fraction in patients with AR?

Output: CMR imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What pro-vides accurate and reproducible measures of regurgitant volume and regurgitation fraction in patients with AR?. ### Response: CMR imaging.


Instruction: What is regurgitant fraction in patients with AR?

Output: regurgitant volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is regurgitant fraction in patients with AR?. ### Response: regurgitant volume.


Instruction: What is an assessment of aortic morphology?

Output: ascending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an assessment of aortic morphology?. ### Response: ascending aorta.


Instruction: How old are patients with a diagnosis of ICH who were documented to have passed the most recent dysphagia screen before oral intake?

Output: ≥18 y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are patients with a diagnosis of ICH who were documented to have passed the most recent dysphagia screen before oral intake?. ### Response: ≥18 y.


Instruction: Have passed the most recent dysphagia screen before oral intake?

Output: Percentage of patients ≥18 y of age with a diagnosis of ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Have passed the most recent dysphagia screen before oral intake?. ### Response: Percentage of patients ≥18 y of age with a diagnosis of ICH.


Instruction: What was excluded from oral intake?

Output: Patients who remained nil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was excluded from oral intake?. ### Response: Patients who remained nil.


Instruction: What was the first oral intake of a patient not consistent with?

Output: the recommendations of the most recent dysphagia screen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the first oral intake of a patient not consistent with?. ### Response: the recommendations of the most recent dysphagia screen.


Instruction: What was the recommendation for thickened liquids?

Output: a single consensus method

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the recommendation for thickened liquids?. ### Response: a single consensus method.


Instruction: How old were the patients with a diagnosis of ICH?

Output: ≥18 y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old were the patients with a diagnosis of ICH?. ### Response: ≥18 y.


Instruction: Who received oral nutrition, fluids, or medication during the hospital stay?

Output: All patients ≥18 y of age with a diagnosis of ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who received oral nutrition, fluids, or medication during the hospital stay?. ### Response: All patients ≥18 y of age with a diagnosis of ICH.


Instruction: Patients who remained nil per os during the entire hospital stay were excluded from receiving what?

Output: oral nutrition, fluids, or medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients who remained nil per os during the entire hospital stay were excluded from receiving what?. ### Response: oral nutrition, fluids, or medication.


Instruction: 18 y of age Length of stay >120 d?

Output: <18 y of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 18 y of age Length of stay >120 d?. ### Response: <18 y of age.


Instruction: What would affect dysphagia screening?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would affect dysphagia screening?. ### Response: stroke.


Instruction: How many times during each hospital stay?

Output: Once

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times during each hospital stay?. ### Response: Once.


Instruction: What would happen if enrolled in a clinical trial?

Output: dysphagia screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would happen if enrolled in a clinical trial?. ### Response: dysphagia screening.


Instruction: What percentage of stroke patients have aspiration?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of stroke patients have aspiration?. ### Response: 50%.


Instruction: What is a prerequisite for pneumonia?

Output: aspiration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prerequisite for pneumonia?. ### Response: aspiration.


Instruction: How many patients with acute stroke are diagnosed with Aspiration Dysphagia?

Output: 67%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with acute stroke are diagnosed with Aspiration Dysphagia?. ### Response: 67%.


Instruction: What percentage of patients who aspirate develop pneumonia?

Output: Up to one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients who aspirate develop pneumonia?. ### Response: Up to one third.


Instruction: Pneumonia is a serious complication of stroke and is associated with what?

Output: increased mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pneumonia is a serious complication of stroke and is associated with what?. ### Response: increased mortality.


Instruction: What has shown a reduction in pneumonia after institutional implementation of dysphagia screening protocols?

Output: Several studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has shown a reduction in pneumonia after institutional implementation of dysphagia screening protocols?. ### Response: Several studies.


Instruction: What has been published in the literature without sufficient evidence to recommend a single consensus method?

Output: swallow screening methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been published in the literature without sufficient evidence to recommend a single consensus method?. ### Response: swallow screening methods.


Instruction: How many screening protocols have been published without randomized control groups?

Output: Several

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many screening protocols have been published without randomized control groups?. ### Response: Several.


Instruction: What have several swallow screening methods been published?

Output: literature

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have several swallow screening methods been published?. ### Response: literature.


Instruction: What should be performed in all patients with dysphagia?

Output: A formal screening procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed in all patients with dysphagia?. ### Response: A formal screening procedure.


Instruction: From what 2015 AHA/ASA guidelines?

Output: Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: From what 2015 AHA/ASA guidelines?. ### Response: Guidelines for the Management of Spontaneous Intracerebral Hemorrhage.


Instruction: What should be performed in all patients before the initiation of oral intake to reduce the risk of pneumonia?

Output: A formal screening procedure for dysphagia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed in all patients before the initiation of oral intake to reduce the risk of pneumonia?. ### Response: A formal screening procedure for dysphagia.


Instruction: What is the Class I; Level of Evidence B?

Output: Spontaneous Intracerebral Hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class I; Level of Evidence B?. ### Response: Spontaneous Intracerebral Hemorrhage.


Instruction: Per patient: documentation of whether a patient had passed the most recent dysphagia screen before oral intake?

Output: Percentage of patients ≥18 y of age with a diagnosis of ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Per patient: documentation of whether a patient had passed the most recent dysphagia screen before oral intake?. ### Response: Percentage of patients ≥18 y of age with a diagnosis of ICH.


Instruction: Per patient population: percentage of patients who received oral intake

Output: passed the most recent dysphagia screen before oral intake

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Per patient population: percentage of patients who received oral intake. ### Response: passed the most recent dysphagia screen before oral intake.


Instruction: What is the percentage of patients who received oral intake and passed the most recent dysphagia screen before oral intake?

Output: Per patient population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of patients who received oral intake and passed the most recent dysphagia screen before oral intake?. ### Response: Per patient population.


Instruction: What may be difficult to locate in chart review?

Output: Documentation of timing of dysphagia screen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be difficult to locate in chart review?. ### Response: Documentation of timing of dysphagia screen.


Instruction: What is the timing of dysphagia screen?

Output: before oral intake

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the timing of dysphagia screen?. ### Response: before oral intake.


Instruction: What is recommended for older adults with hypertension and a high burden of comorbidity?

Output: clinical judgment, patient preference, and a team-based approach to assess risk/benefit are reasonable for decisions regarding intensity of BP lowering and choice of antihypertensive drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for older adults with hypertension and a high burden of comorbidity?. ### Response: clinical judgment, patient preference, and a team-based approach to assess risk/benefit are reasonable for decisions regarding intensity of BP lowering and choice of antihypertensive drugs.


Instruction: What are reasonable for decisions regarding intensity of BP lowering?

Output: clinical judgment, patient preference, and a team-based approach to assess risk/benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are reasonable for decisions regarding intensity of BP lowering?. ### Response: clinical judgment, patient preference, and a team-based approach to assess risk/benefit.


Instruction: What is reasonable for decisions regarding intensity of BP lowering and choice of antihypertensive drugs?

Output: clinical judgment, patient preference, and a team-based approach to assess risk/benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for decisions regarding intensity of BP lowering and choice of antihypertensive drugs?. ### Response: clinical judgment, patient preference, and a team-based approach to assess risk/benefit.


Instruction: What is beneficial for identification of patients with undiagnosed or undertreated hypertension?

Output: Use of the EHR and patient registries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial for identification of patients with undiagnosed or undertreated hypertension?. ### Response: Use of the EHR and patient registries.


Instruction: What is recommended for noninstitutionalized ambulatory community-dwelling adults (65 y of age) with an average SBP of 130 mm Hg or higher?

Output: Treatment of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for noninstitutionalized ambulatory community-dwelling adults (65 y of age) with an average SBP of 130 mm Hg or higher?. ### Response: Treatment of hypertension.


Instruction: How long should an adult with stage 2 hypertension be evaluated by or referred to a primary care provider?

Output: within 1 month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should an adult with stage 2 hypertension be evaluated by or referred to a primary care provider?. ### Response: within 1 month.


Instruction: How many agents of different classes are used in nonpharmacological and antihypertensive drug therapy?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many agents of different classes are used in nonpharmacological and antihypertensive drug therapy?. ### Response: 2.


Instruction: How many agents of different classes are used?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many agents of different classes are used?. ### Response: 2.


Instruction: How long does it take to have a repeat BP evaluation?

Output: 1 month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to have a repeat BP evaluation?. ### Response: 1 month.


Instruction: What is the class of evidence for B-R?

Output: Class 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of evidence for B-R?. ### Response: Class 1.


Instruction: What is a reasonable way to screen for the presence of white coat hypertension?

Output: daytime ABPM or HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable way to screen for the presence of white coat hypertension?. ### Response: daytime ABPM or HBPM.


Instruction: What is the class 2a, Level of Evidence?

Output: B-NR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class 2a, Level of Evidence?. ### Response: B-NR.


Instruction: What is the acronym for the PCPI National Quality Registry Network?

Output: NQRN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the PCPI National Quality Registry Network?. ### Response: NQRN.


Instruction: What is another name for the American Heart Association?

Output: AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the American Heart Association?. ### Response: AHA.


Instruction: What is NCQA?

Output: Controlling High Blood Pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NCQA?. ### Response: Controlling High Blood Pressure.


Instruction: What relies on average BP readings?

Output: 2017 Hypertension Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What relies on average BP readings?. ### Response: 2017 Hypertension Clinical Practice Guidelines.


Instruction: How does NCQA HEDIS measure BP?

Output: most recent BP reading

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does NCQA HEDIS measure BP?. ### Response: most recent BP reading.


Instruction: What is compliant if the BP is 140/90 mm Hg?

Output: numerator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is compliant if the BP is 140/90 mm Hg?. ### Response: numerator.


Instruction: What if there is no BP reading during the measurement year?

Output: ≥140/90 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What if there is no BP reading during the measurement year?. ### Response: ≥140/90 mm Hg.


Instruction: What is the representative BP?

Output: lowest systolic and diastolic BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the representative BP?. ### Response: lowest systolic and diastolic BP.


Instruction: What does ABPM mean?

Output: ambulatory blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ABPM mean?. ### Response: ambulatory blood pressure monitoring.


Instruction: AHA is what?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AHA is what?. ### Response: American Heart Association.


Instruction: CVD stands for cardiovascular disease; DBP stands for diastolic blood pressure; EHR stands for what?

Output: electronic health record

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CVD stands for cardiovascular disease; DBP stands for diastolic blood pressure; EHR stands for what?. ### Response: electronic health record.


Instruction: HBPM stands for home blood pressure monitoring; what stands for heart failure?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HBPM stands for home blood pressure monitoring; what stands for heart failure?. ### Response: HF.


Instruction: What stands for Healthcare Effectiveness Data and Information Set?

Output: HEDIS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What stands for Healthcare Effectiveness Data and Information Set?. ### Response: HEDIS.


Instruction: What is the primary limitation of vasodilator?

Output: short duration of benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary limitation of vasodilator?. ### Response: short duration of benefit.


Instruction: What is used less frequently because it can produce neurotoxic-ity?

Output: Papaverine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used less frequently because it can produce neurotoxic-ity?. ### Response: Papaverine.


Instruction: What is the primary limitation of vasodilator therapy?

Output: short duration of benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary limitation of vasodilator therapy?. ### Response: short duration of benefit.


Instruction: There have been no randomized trials of what?

Output: hemodynamic augmenta-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There have been no randomized trials of what?. ### Response: hemodynamic augmenta-tion.


Instruction: What should be administered to all patients with aSAH (Class I; Level of Evidence A)?

Output: Oral nimodipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be administered to all patients with aSAH (Class I; Level of Evidence A)?. ### Response: Oral nimodipine.


Instruction: What has been shown to improve neurological outcomes but not cerebral vasospasm?

Output: Oral nimodipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to improve neurological outcomes but not cerebral vasospasm?. ### Response: Oral nimodipine.


Instruction: What is recommended to prevent DCI?

Output: Maintenance of euvolemia and normal circulatingblood volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to prevent DCI?. ### Response: Maintenance of euvolemia and normal circulatingblood volume.


Instruction: When was the Class 1724 Stroke June 2012?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Class 1724 Stroke June 2012?. ### Response: April 28, 2023.


Instruction: O'Gara and colleagues 2013 ACCF/AHA STEMI Guideline e367therapy?

Output: reper -fusion therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: O'Gara and colleagues 2013 ACCF/AHA STEMI Guideline e367therapy?. ### Response: reper -fusion therapy.


Instruction: Antithrombotic therapy, glycoprotein IIb/IIIa inhibitor therapy, pharmacotherapy, proton-pump inhibitor, implantable cardioverter-defibrillator therapy, what?

Output: cardiogenic shock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antithrombotic therapy, glycoprotein IIb/IIIa inhibitor therapy, pharmacotherapy, proton-pump inhibitor, implantable cardioverter-defibrillator therapy, what?. ### Response: cardiogenic shock.


Instruction: What subtopics did the committee cross-reference?

Output: percutaneous coronary intervention, coronary artery bypass graft, cardiac rehabilitation, and secondary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What subtopics did the committee cross-reference?. ### Response: percutaneous coronary intervention, coronary artery bypass graft, cardiac rehabilitation, and secondary prevention.


Instruction: What was the subject matter previously published by the ACCF and AHA?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the subject matter previously published by the ACCF and AHA?. ### Response: percutaneous coronary intervention.


Instruction: Who previously published the guideline?

Output: ACCF and AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who previously published the guideline?. ### Response: ACCF and AHA.


Instruction: What are the references selected and published in this document?

Output: representative and not all-inclusive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the references selected and published in this document?. ### Response: representative and not all-inclusive.


Instruction: The absolute risk difference and number needed to treat or harm are provided in what?

Output: the guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The absolute risk difference and number needed to treat or harm are provided in what?. ### Response: the guideline.


Instruction: What is the focus of this guideline?

Output: tool for practitioners

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of this guideline?. ### Response: tool for practitioners.


Instruction: What is included in the guideline along with confidence intervals?

Output: the abso-lute risk difference and number needed to treat or harm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in the guideline along with confidence intervals?. ### Response: the abso-lute risk difference and number needed to treat or harm.


Instruction: What is STEMI?

Output: management of patients with ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is STEMI?. ### Response: management of patients with ST-elevation myocardial infarction.


Instruction: When were updates to the 2004 STEMI guideline published?

Output: 2007 and 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were updates to the 2004 STEMI guideline published?. ### Response: 2007 and 2009.


Instruction: What is the focus of the guideline?

Output: tool for practitioners

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the guideline?. ### Response: tool for practitioners.


Instruction: What is the purpose of the guideline?

Output: To provide clinicians with a comprehensive set of data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of the guideline?. ### Response: To provide clinicians with a comprehensive set of data.


Instruction: What is narrower in scope than the 2004 STEMI Guideline in an attempt to provide a more focused tool?

Output: the document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is narrower in scope than the 2004 STEMI Guideline in an attempt to provide a more focused tool?. ### Response: the document.


Instruction: What is PCI?

Output: percutaneous coronary interven-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PCI?. ### Response: percutaneous coronary interven-tion.


Instruction: What is CABG?

Output: coronary artery bypass graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CABG?. ### Response: coronary artery bypass graft.


Instruction: Who was the writing committee composed of?

Output: experts representing cardiovascular medicine, interventional cardiology, electro-physiology, HF, cardiac surgery, emergency medicine, inter -nal medicine, cardiac rehabilitation, nursing, and pharmacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the writing committee composed of?. ### Response: experts representing cardiovascular medicine, interventional cardiology, electro-physiology, HF, cardiac surgery, emergency medicine, inter -nal medicine, cardiac rehabilitation, nursing, and pharmacy.


Instruction: Who assigned official representatives?

Output: The American College of Physicians, American College of Emergency Physicians, and Society for Cardiovascular Angi-ography and Interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who assigned official representatives?. ### Response: The American College of Physicians, American College of Emergency Physicians, and Society for Cardiovascular Angi-ography and Interventions.


Instruction: How many outside reviewers reviewed the document?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many outside reviewers reviewed the document?. ### Response: 2.


Instruction: How many outside reviewers did this document receive?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many outside reviewers did this document receive?. ### Response: 2.


Instruction: How many individual content reviewers were included in this document?

Output: 22

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many individual content reviewers were included in this document?. ### Response: 22.


Instruction: Who are the individual content reviewers?

Output: members from the ACCF Interventional Scientific Council and ACCF Surgeons’ Scientific Council

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who are the individual content reviewers?. ### Response: members from the ACCF Interventional Scientific Council and ACCF Surgeons’ Scientific Council.


Instruction: What is the RWI information of a content reviewer?

Output: All reviewer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the RWI information of a content reviewer?. ### Response: All reviewer.


Instruction: What can nitrate therapy reduce pulmonary congestion and improve exercise tolerance in patients with HFr EF?

Output: NEAT-HFp EF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can nitrate therapy reduce pulmonary congestion and improve exercise tolerance in patients with HFr EF?. ### Response: NEAT-HFp EF.


Instruction: What is the current recommendation?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current recommendation?. ### Response: 2013.


Instruction: What did the NEAT-HFp EF trial171 randomized 110 patients with EF 50% on?

Output: stable HF therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the NEAT-HFp EF trial171 randomized 110 patients with EF 50% on?. ### Response: stable HF therapy.


Instruction: What isosorbide mononitrate or placebo did not have any beneficial effects on?

Output: activity levels, QoL, exercise tolerance, or NT-proBNP levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isosorbide mononitrate or placebo did not have any beneficial effects on?. ### Response: activity levels, QoL, exercise tolerance, or NT-proBNP levels.


Instruction: What was not recommended in patients with HFp EF?

Output: routine use of nitrates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not recommended in patients with HFp EF?. ### Response: routine use of nitrates.


Instruction: What is not recommended for patients with HFp EF and symptomatic CAD?

Output: routine use of nitrates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for patients with HFp EF and symptomatic CAD?. ### Response: routine use of nitrates.


Instruction: What does Phosphodiesterase-5 inhibition augment the nitric oxide system by upregulating?

Output: cGMP activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Phosphodiesterase-5 inhibition augment the nitric oxide system by upregulating?. ### Response: cGMP activity.


Instruction: How many patients were randomized to phosphodiesterase-5 inhibition with sildenafil or placebo?

Output: 216

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were randomized to phosphodiesterase-5 inhibition with sildenafil or placebo?. ### Response: 216.


Instruction: What did this study not show?

Output: improvement in oxygen consumption or exercise tolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did this study not show?. ### Response: improvement in oxygen consumption or exercise tolerance.


Instruction: What did this study not show improvement in?

Output: oxygen consumption or exercise tolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did this study not show improvement in?. ### Response: oxygen consumption or exercise tolerance.


Instruction: What is not recommended for patients with HFpEF?

Output: routine use of nitrates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for patients with HFpEF?. ### Response: routine use of nitrates.


Instruction: What might be reasonable to improve functional status and QoL in patients with NYHA class II and IIIHF and iron deficiency?

Output: intravenous iron replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be reasonable to improve functional status and QoL in patients with NYHA class II and IIIHF and iron deficiency?. ### Response: intravenous iron replacement.


Instruction: If transferrin saturation is 20%, how many ng/mL of iron should be taken?

Output: 100 to 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If transferrin saturation is 20%, how many ng/mL of iron should be taken?. ### Response: 100 to 300.


Instruction: What is the baseline baseline for intravenous iron replacement?

Output: hepcidin deficiency in HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the baseline baseline for intravenous iron replacement?. ### Response: hepcidin deficiency in HF.


Instruction: What is independently associated with HF disease severity?

Output: Anemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is independently associated with HF disease severity?. ### Response: Anemia.


Instruction: Iron deficiency appears to be uniquely associated with what?

Output: reduced exercise capacity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Iron deficiency appears to be uniquely associated with what?. ### Response: reduced exercise capacity.


Instruction: What is uniquely associated with reduced exercise capacity?

Output: iron deficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uniquely associated with reduced exercise capacity?. ### Response: iron deficiency.


Instruction: When iron deficiency is diagnosed and after full evaluation for cause, what can intravenous repletion of iron do?

Output: improve exercise capacity and QoL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When iron deficiency is diagnosed and after full evaluation for cause, what can intravenous repletion of iron do?. ### Response: improve exercise capacity and QoL.


Instruction: What may improve exercise capacity and QoL?

Output: intravenous repletion of iron

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may improve exercise capacity and QoL?. ### Response: intravenous repletion of iron.


Instruction: What has been underpowered to detect reductions in hard clinical endpoints?

Output: controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been underpowered to detect reductions in hard clinical endpoints?. ### Response: controlled trials.


Instruction: What is the FAIR-HF?

Output: Ferric Carboxymaltose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the FAIR-HF?. ### Response: Ferric Carboxymaltose.


Instruction: What should be administered to UA/NSTEMI patients as soon as possible after hospital presentation?

Output: Aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be administered to UA/NSTEMI patients as soon as possible after hospital presentation?. ### Response: Aspirin.


Instruction: What should continue indefinitely in patients who tolerate it?

Output: Aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should continue indefinitely in patients who tolerate it?. ### Response: Aspirin.


Instruction: What should be administered to UA/NSTEMIpatients who are unable to take aspirin because of hypersensitivity or major GI intolerance?

Output: †9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be administered to UA/NSTEMIpatients who are unable to take aspirin because of hypersensitivity or major GI intolerance?. ### Response: †9.


Instruction: Why should patients receive dual antiplatelet therapy on presentation?

Output: Patients with definite UA/NSTEMI at medium or high risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why should patients receive dual antiplatelet therapy on presentation?. ### Response: Patients with definite UA/NSTEMI at medium or high risk.


Instruction: What should be initiated onpresentation?

Output: Aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be initiated onpresentation?. ### Response: Aspirin.


Instruction: How many concurrent P2Y12receptorinhibitors are there?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many concurrent P2Y12receptorinhibitors are there?. ### Response: 2.


Instruction: What is not recommended in the case of aspirin?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended in the case of aspirin?. ### Response: P2Y12receptorinhibitors.


Instruction: What is not recommended in the case of aspirin allergy?

Output: 2 concurrent P2Y12receptorinhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended in the case of aspirin allergy?. ### Response: 2 concurrent P2Y12receptorinhibitors.


Instruction: What is the recommended GP IIb/IIIainhibitors?

Output: IV eptifibatide and tirofiban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended GP IIb/IIIainhibitors?. ### Response: IV eptifibatide and tirofiban.


Instruction: What are the preferred GP IIb/IIIainhibitors?

Output: IV eptifibatide and tirofiban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the preferred GP IIb/IIIainhibitors?. ### Response: IV eptifibatide and tirofiban.


Instruction: At the time of PCI, what if not started before PCI13,16 (Level of Evidence: A)?

Output: Clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At the time of PCI, what if not started before PCI13,16 (Level of Evidence: A)?. ### Response: Clopidogrel.


Instruction: What should be added to aspirin and anticoagulant therapy as soon as possible after admission?

Output: clopidogrel or ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be added to aspirin and anticoagulant therapy as soon as possible after admission?. ### Response: clopidogrel or ticagrelor.


Instruction: How long should clopidogrel be given to UA/NSTEMI patients?

Output: up to 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should clopidogrel be given to UA/NSTEMI patients?. ### Response: up to 12 months.


Instruction: What is the duration of therapy for UA/NSTEMI patients?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the duration of therapy for UA/NSTEMI patients?. ### Response: 12 months.


Instruction: What should be performed if recurrent symptoms/ischemia, heartfailure, or serious arrhythmias subsequently appear?

Output: diagnostic angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed if recurrent symptoms/ischemia, heartfailure, or serious arrhythmias subsequently appear?. ### Response: diagnostic angiography.


Instruction: What type of angiography should be performed?

Output: diagnostic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of angiography should be performed?. ### Response: diagnostic.


Instruction: What should be added to aspirin?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be added to aspirin?. ### Response: clopidogrel.


Instruction: What should be added to aspirin and anticoagulant therapy before diagnosticangiography?

Output: ticagrelor†

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be added to aspirin and anticoagulant therapy before diagnosticangiography?. ### Response: ticagrelor†.


Instruction: What is the Level of Evidence?

Output: A)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence?. ### Response: A).


Instruction: What is the survival rate for mold-related IE patients?

Output: <20%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the survival rate for mold-related IE patients?. ### Response: <20%..


Instruction: How many treatment doctrines have prevailed in fungal IE?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many treatment doctrines have prevailed in fungal IE?. ### Response: 2.


Instruction: What is a stand-alone indication for surgical replacement of an infected valve?

Output: Fungal IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a stand-alone indication for surgical replacement of an infected valve?. ### Response: Fungal IE.


Instruction: What is the initial drug of choice for fungal IE?

Output: amphotericin B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the initial drug of choice for fungal IE?. ### Response: amphotericin B.


Instruction: What is the name of a fungicidal drug?

Output: amphotericin B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a fungicidal drug?. ### Response: amphotericin B.


Instruction: What does re-evaluation of antifungal principles seem to be in order with the availability of?

Output: newer antifungal drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does re-evaluation of antifungal principles seem to be in order with the availability of?. ### Response: newer antifungal drugs.


Instruction: Why should revaluation be based on anec-dotal experience and expert opinion?

Output: rarity of the syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why should revaluation be based on anec-dotal experience and expert opinion?. ### Response: rarity of the syndrome.


Instruction: On what date was the data downloaded from http://ahajournals.org?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was the data downloaded from http://ahajournals.org?. ### Response: April 28, 2023.


Instruction: What is the name of the journal that deals with intracranial bleeding?

Output: JAMA Neurol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that deals with intracranial bleeding?. ### Response: JAMA Neurol.


Instruction: What is apixaban versus warfarin compared to?

Output: prothrombin time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is apixaban versus warfarin compared to?. ### Response: prothrombin time.


Instruction: Who is Granger CB?

Output: Lopes RD, Hanna M, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Granger CB?. ### Response: Lopes RD, Hanna M, et al.


Instruction: What was the endpoint of the Aristitle trial?

Output: control and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the endpoint of the Aristitle trial?. ### Response: control and safety.


Instruction: What is the name of the apixaban versus warfarin study?

Output: ENGAGE AF-TIMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the apixaban versus warfarin study?. ### Response: ENGAGE AF-TIMI.


Instruction: Which drug was used to reduce the thromboembolic events in atrial fibrillation?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug was used to reduce the thromboembolic events in atrial fibrillation?. ### Response: warfarin.


Instruction: What is the ROCKET AFexperience?

Output: End of study transition from study drug to open-label vitamin K antagonist therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ROCKET AFexperience?. ### Response: End of study transition from study drug to open-label vitamin K antagonist therapy.


Instruction: What was the end of study transition from blinded study drug to open-label anticoagulation?

Output: ENGAGE AF-TIMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the end of study transition from blinded study drug to open-label anticoagulation?. ### Response: ENGAGE AF-TIMI.


Instruction: What is the name of the study of patients from blinded study drug to open-label anticoagulation: the ENGAGE AF-TIMI 48 tr ial?

Output: ROCKET AFexperience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study of patients from blinded study drug to open-label anticoagulation: the ENGAGE AF-TIMI 48 tr ial?. ### Response: ROCKET AFexperience.


Instruction: What was the 2014 J Am Coll Cardiol 64(6):576-584.117?

Output: open-label anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2014 J Am Coll Cardiol 64(6):576-584.117?. ### Response: open-label anticoagulation.


Instruction: How was the effectiveness of pharmacist-managed warfarin compared to other models?

Output: Comparing the effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the effectiveness of pharmacist-managed warfarin compared to other models?. ### Response: Comparing the effectiveness.


Instruction: What is the name of the systematic review and meta-analysis?

Output: Comparing the effectiveness of pharmacist-managed warfarin anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis?. ### Response: Comparing the effectiveness of pharmacist-managed warfarin anticoagulation.


Instruction: What was the J Clin Pharm Ther. 2016;41(6):602-611.118.

Output: Comparing the effectiveness of pharmacist-managed warfarin anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Clin Pharm Ther. 2016;41(6):602-611.118.. ### Response: Comparing the effectiveness of pharmacist-managed warfarin anticoagulation.


Instruction: What did Airee A, Guirguis AB, Mohammad RA do?

Output: Clinical outcomes and pharmacists ’acceptance of a community hospital ’s anticoagulation management serviceutilizing decentralized clinical staff pharmacists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Airee A, Guirguis AB, Mohammad RA do?. ### Response: Clinical outcomes and pharmacists ’acceptance of a community hospital ’s anticoagulation management serviceutilizing decentralized clinical staff pharmacists.


Instruction: What is the INR?

Output: prothrombin time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the INR?. ### Response: prothrombin time.


Instruction: What are the main characteristics of patients on warfarin treatment in primaryhealth care centers and anticoagulation clinics?

Output: prothrombin time (INR) results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the main characteristics of patients on warfarin treatment in primaryhealth care centers and anticoagulation clinics?. ### Response: prothrombin time (INR) results.


Instruction: BMC Health Serv Res. 2013;13(1):85.120.

Output: BMC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BMC Health Serv Res. 2013;13(1):85.120.. ### Response: BMC.


Instruction: What is the impact of an inpatient anticoagulation management service on clinical outcomes?

Output: acceptance of a community hospital ’s anticoagulation management serviceutilizing decentralized clinical staff pharmacists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of an inpatient anticoagulation management service on clinical outcomes?. ### Response: acceptance of a community hospital ’s anticoagulation management serviceutilizing decentralized clinical staff pharmacists.


Instruction: What did Chamberlain MA, Sageser NA, Ruiz D compare with?

Output: outcomes from traditional care in a family medic ineclinic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Chamberlain MA, Sageser NA, Ruiz D compare with?. ### Response: outcomes from traditional care in a family medic ineclinic.


Instruction: When did J Am Board Fam Pract issue 14(1):16-21.122?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Board Fam Pract issue 14(1):16-21.122?. ### Response: 2001.


Instruction: What is the main difference between an anticoagulation clinic and usual medical care?

Output: anticoagulation control, patient outcomes, andhealth care costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the main difference between an anticoagulation clinic and usual medical care?. ### Response: anticoagulation control, patient outcomes, andhealth care costs.


Instruction: What is a major difference between a pharmacotherapeutic programme and a normal medical care clinic?

Output: anticoagulation control, patient outcomes, andhealth care costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major difference between a pharmacotherapeutic programme and a normal medical care clinic?. ### Response: anticoagulation control, patient outcomes, andhealth care costs.


Instruction: What is the effect of a pharmacotherapeutic programme on control and safety of long-term anticoagulation treatment?

Output: Impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of a pharmacotherapeutic programme on control and safety of long-term anticoagulation treatment?. ### Response: Impact.


Instruction: Where was the study conducted?

Output: Spain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the study conducted?. ### Response: Spain.


Instruction: What was the outcome of the study?

Output: transition from study drug to open-label vitamin K antagonist therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the study?. ### Response: transition from study drug to open-label vitamin K antagonist therapy.


Instruction: How long did the study last?

Output: 4 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: 4 years.


Instruction: What did Garton L, Crosby JF, use to compare physician management with pharmacist-managed anticoagulation clinic?

Output: intern ationalnormalized ratio stability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Garton L, Crosby JF, use to compare physician management with pharmacist-managed anticoagulation clinic?. ### Response: intern ationalnormalized ratio stability.


Instruction: What was the name of the study that compared physician management and pharmacist management?

Output: A retrospective assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that compared physician management and pharmacist management?. ### Response: A retrospective assessment.


Instruction: In what year did JThrombolysis publish its 32(4):426-430?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did JThrombolysis publish its 32(4):426-430?. ### Response: 2011.


Instruction: What is an anatomy for PCI and who are good candidates forCABG?

Output: patients with complex 3-vesselCAD (eg, SYNTAX score >22), with or withoutinvolvement of the proximal LAD artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an anatomy for PCI and who are good candidates forCABG?. ### Response: patients with complex 3-vesselCAD (eg, SYNTAX score >22), with or withoutinvolvement of the proximal LAD artery.


Instruction: What is beneficial in patients with significant (>70% diameter) stenoses in 3major coronary arteries?

Output: CABG to improve survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial in patients with significant (>70% diameter) stenoses in 3major coronary arteries?. ### Response: CABG to improve survival.


Instruction: How many other major coronary arteries are there?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many other major coronary arteries are there?. ### Response: 1.


Instruction: What is beneficial insurvivors of sudden cardiac death with presumedischemia-mediated ventricular tachycardia?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial insurvivors of sudden cardiac death with presumedischemia-mediated ventricular tachycardia?. ### Response: CABG.


Instruction: What is CABG Level of Evidence?

Output: B271,345,347

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CABG Level of Evidence?. ### Response: B271,345,347.


Instruction: What is the PCI level of evidence?

Output: C345

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PCI level of evidence?. ### Response: C345.


Instruction: How much perfusion defect by myocardialperfusion is reasonable?

Output: >20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much perfusion defect by myocardialperfusion is reasonable?. ### Response: >20%.


Instruction: How much perfusion defect does myocardialperfusion stress imaging detect?

Output: >20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much perfusion defect does myocardialperfusion stress imaging detect?. ### Response: >20%.


Instruction: What is the level of evidence for CABG in patients with mild-moderate LV systolic dysfunction?

Output: reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for CABG in patients with mild-moderate LV systolic dysfunction?. ### Response: reasonable.


Instruction: What is significant in patients with significant stenosis in the proximal LAD artery and evi-dence of the coronary artery?

Output: CABG to improve survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is significant in patients with significant stenosis in the proximal LAD artery and evi-dence of the coronary artery?. ### Response: CABG to improve survival.


Instruction: When viable myocardium is present in the region of intended revascularization, what should be done?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When viable myocardium is present in the region of intended revascularization, what should be done?. ### Response: CABG.


Instruction: What type of stenosis in the proximal LAD artery and evi-dence of extensive ischemia are two examples of what?

Output: significant ( >70% diam-eter) stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stenosis in the proximal LAD artery and evi-dence of extensive ischemia are two examples of what?. ### Response: significant ( >70% diam-eter) stenosis.


Instruction: What is the level of Evi-ence: B)4?

Output: 87,88,318,343

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of Evi-ence: B)4?. ### Response: 87,88,318,343.


Instruction: Why is it reasonable to choose CABG over PCI?

Output: to im-prove survival in patients with complex 3-vesselCAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is it reasonable to choose CABG over PCI?. ### Response: to im-prove survival in patients with complex 3-vesselCAD.


Instruction: What is a good candidate for CABG?

Output: SIHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a good candidate for CABG?. ### Response: SIHD.


Instruction: What type of graft can be anastomosed to the LAD artery?

Output: LIMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of graft can be anastomosed to the LAD artery?. ### Response: LIMA.


Instruction: What is uncertain about CABG in patients with significant steno-ses in 2 major coronary arteries not involving theproximal LAD artery and without extensive ische-mia?

Output: The usefulness of CABG to improve survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uncertain about CABG in patients with significant steno-ses in 2 major coronary arteries not involving theproximal LAD artery and without extensive ische-mia?. ### Response: The usefulness of CABG to improve survival.


Instruction: What isuncertain about the usefulness of PCI to improve survival?

Output: uncer-tain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isuncertain about the usefulness of PCI to improve survival?. ### Response: uncer-tain.


Instruction: What might be considered with the primary or soleintent of improving survival in patients with SIHD with severe LV systolic dysfunction (EF 35%)?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered with the primary or soleintent of improving survival in patients with SIHD with severe LV systolic dysfunction (EF 35%)?. ### Response: CABG.


Instruction: What is uncer-tain for patients with 2- or 3-vessel CAD?

Output: PCI to improve survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uncer-tain for patients with 2- or 3-vessel CAD?. ### Response: PCI to improve survival.


Instruction: What percentage of SIHD patients have severe LV systolic dysfunction?

Output: <35%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of SIHD patients have severe LV systolic dysfunction?. ### Response: <35%).


Instruction: What type of myocardium is present in patients with SIHD?

Output: viable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of myocardium is present in patients with SIHD?. ### Response: viable.


Instruction: What is native to waiting 3 weeks before cardioversion?

Output: to perform transesophageal echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is native to waiting 3 weeks before cardioversion?. ### Response: to perform transesophageal echocardiography.


Instruction: What is to perform transesophageal echocardiography to exclude thrombus?

Output: native to waiting 3 weeks before cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is to perform transesophageal echocardiography to exclude thrombus?. ### Response: native to waiting 3 weeks before cardioversion.


Instruction: The decision about long-term anticoagulant therapy is based on what?

Output: thromboembolic risk profile (Section 4) and bleeding risk profile

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The decision about long-term anticoagulant therapy is based on what?. ### Response: thromboembolic risk profile (Section 4) and bleeding risk profile.


Instruction: What is the “48-hour rule”?

Output: lasting <48 hours is in the range of 0.7% to 1.1%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the “48-hour rule”?. ### Response: lasting <48 hours is in the range of 0.7% to 1.1%,.


Instruction: What was associated with a greater risk of thromboembolic complications than cardioversion of less than 12 hours?

Output: delay to car -dioversion of 12 hours or longer from symp-tom onset

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a greater risk of thromboembolic complications than cardioversion of less than 12 hours?. ### Response: delay to car -dioversion of 12 hours or longer from symp-tom onset.


Instruction: What is the risk of thromboembolic complications with cardioversion of 12 hour or longer in patients >75 years of age and in women?

Output: increases substantially

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of thromboembolic complications with cardioversion of 12 hour or longer in patients >75 years of age and in women?. ### Response: increases substantially.


Instruction: The data supporting the safety of current prac-tices of cardioversion without oral anticoag-ulation in patients with AF duration 48 hours is what?

Output: limited

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The data supporting the safety of current prac-tices of cardioversion without oral anticoag-ulation in patients with AF duration 48 hours is what?. ### Response: limited.


Instruction: What is the risk of thromboembolic complica-tion after a cardioversion for AF lasting 48 hours?

Output: 0.7% to 1.1%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of thromboembolic complica-tion after a cardioversion for AF lasting 48 hours?. ### Response: 0.7% to 1.1%,.


Instruction: How long is the duration of AF without oral anticoagulation in patients with AF?

Output: <48 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the duration of AF without oral anticoagulation in patients with AF?. ### Response: <48 hours.


Instruction: What is the risk of throm-boembolism in patients with risk factors that include female sex, HF, and diabetes mellitus?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of throm-boembolism in patients with risk factors that include female sex, HF, and diabetes mellitus?. ### Response: higher.


Instruction: Patients 60 years of age without thromboembolic risk factors and those with postoperative AF appear to have a lower risk?

Output: lower risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients 60 years of age without thromboembolic risk factors and those with postoperative AF appear to have a lower risk?. ### Response: lower risk.


Instruction: How many cardioversions in 484 patients were there in 1 study?

Output: 567

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cardioversions in 484 patients were there in 1 study?. ### Response: 567.


Instruction: How many patients had cardioversions?

Output: 484

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had cardioversions?. ### Response: 484.


Instruction: How much higher was the risk of throm-boembolism in patients without therapeutic anticoagulation?

Output: 5 times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was the risk of throm-boembolism in patients without therapeutic anticoagulation?. ### Response: 5 times.


Instruction: What was the CHA2DS2-VASc score of patients with 2.S6.1.1-14?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the CHA2DS2-VASc score of patients with 2.S6.1.1-14?. ### Response: ≥.


Instruction: What is the score of 2.S6.1.1-14?

Output: CHA2DS2-VASc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the score of 2.S6.1.1-14?. ### Response: CHA2DS2-VASc.


Instruction: What should be weighed against the risk of anticoagulant-related bleeding for the individual patient?

Output: the risk of thromboembolic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be weighed against the risk of anticoagulant-related bleeding for the individual patient?. ### Response: the risk of thromboembolic events.


Instruction: How long did cardio-version for AF last?

Output: <48 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did cardio-version for AF last?. ### Response: <48 hours.


Instruction: How long does cardio-version for AF last?

Output: <48 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does cardio-version for AF last?. ### Response: <48 hours.


Instruction: How many patients had cardioversions in 1 study?

Output: 567

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had cardioversions in 1 study?. ### Response: 567.


Instruction: What was the risk of throm-boembolism in patients without therapeutic anticoagulation?

Output: nearly 5 times higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of throm-boembolism in patients without therapeutic anticoagulation?. ### Response: nearly 5 times higher.


Instruction: What was the overall event rate for patients with AF lasting 48 hours and a CHA2DS2-VASc score 1?

Output: 1.1%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall event rate for patients with AF lasting 48 hours and a CHA2DS2-VASc score 1?. ### Response: 1.1%.


Instruction: What group accounted for 10 of the 38 thromboembolic events that occurred in the study?

Output: CHA2DS2-VASc score of <2.S6.1.1-14 In the second study, for patients with AF lasting <48 hours and a CHA2DS2-VASc score ≤1, the overall event rate was low (0.4%), but this group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group accounted for 10 of the 38 thromboembolic events that occurred in the study?. ### Response: CHA2DS2-VASc score of <2.S6.1.1-14 In the second study, for patients with AF lasting <48 hours and a CHA2DS2-VASc score ≤1, the overall event rate was low (0.4%), but this group.


Instruction: How many thromboembolic events were there in the study?

Output: 38

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many thromboembolic events were there in the study?. ### Response: 38.


Instruction: What percentage of the events that occurred in this study occurred in the research?

Output: 26%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the events that occurred in this study occurred in the research?. ### Response: 26%).


Instruction: These studies agree with prior studies of cardioversion in short-term what?

Output: AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: These studies agree with prior studies of cardioversion in short-term what?. ### Response: AF.


Instruction: What were the four final categories for the quality of overall evidence?

Output: ‘A’ , ‘B’ , ‘C’ or ‘D’

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the four final categories for the quality of overall evidence?. ### Response: ‘A’ , ‘B’ , ‘C’ or ‘D’.


Instruction: What was the net health benefit determined on the basis of?

Output: the anticipated balance of beneﬁts and harmsacross all clinically important outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the net health benefit determined on the basis of?. ### Response: the anticipated balance of beneﬁts and harmsacross all clinically important outcomes.


Instruction: How was benefit determined?

Output: onthe basis of the anticipated balance of beneﬁts and harmsacross all clinically important outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was benefit determined?. ### Response: onthe basis of the anticipated balance of beneﬁts and harmsacross all clinically important outcomes.


Instruction: What was the basis for benefit determination?

Output: anticipated balance of beneﬁts and harmsacross all clinically important outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the basis for benefit determination?. ### Response: anticipated balance of beneﬁts and harmsacross all clinically important outcomes.


Instruction: Who assessed net benefit?

Output: Work Group and the ERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who assessed net benefit?. ### Response: Work Group and the ERT.


Instruction: How is the strength of a recommendation graded?

Output: level 1 or level 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the strength of a recommendation graded?. ### Response: level 1 or level 2.


Instruction: How is a recommendation graded?

Output: level 1 orlevel 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is a recommendation graded?. ### Response: level 1 orlevel 2.


Instruction: What is the KDIGO nomenclature for grading?

Output: the strength of a recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the KDIGO nomenclature for grading?. ### Response: the strength of a recommendation.


Instruction: A recommendation can be for or against what?

Output: doing something

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A recommendation can be for or against what?. ### Response: doing something.


Instruction: How is the strength of a recommendation determined?

Output: level 1 or level 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the strength of a recommendation determined?. ### Response: level 1 or level 2.


Instruction: What type of decision analyses were not conducted?

Output: Formal decision analyses including cost analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of decision analyses were not conducted?. ### Response: Formal decision analyses including cost analysis.


Instruction: What category was designed to allow the Work Group to issue general advice?

Output: Ungraded statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What category was designed to allow the Work Group to issue general advice?. ### Response: Ungraded statements.


Instruction: What does notconducted.Ungraded statements meet?

Output: systematic evidence review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does notconducted.Ungraded statements meet?. ### Response: systematic evidence review.


Instruction: What is not based on systematic evidence review?

Output: Ungraded statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not based on systematic evidence review?. ### Response: Ungraded statements.


Instruction: What are examples of common examples?

Output: recommendations about frequency of testing, referralto specialists, and routine medical care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are examples of common examples?. ### Response: recommendations about frequency of testing, referralto specialists, and routine medical care.


Instruction: How did we try to minimize the use of ungraded recommendations?

Output: This grading scheme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did we try to minimize the use of ungraded recommendations?. ### Response: This grading scheme.


Instruction: How many levels of grading the quality of evidence was adopted by the KDIGO Board in December 2008?

Output: four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many levels of grading the quality of evidence was adopted by the KDIGO Board in December 2008?. ### Response: four.


Instruction: What did the Work Group take on the primary role of writing the recommendations?

Output: rationale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group take on the primary role of writing the recommendations?. ### Response: rationale.


Instruction: What was the primary role of writing the recommendations and rationale?

Output: The Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary role of writing the recommendations and rationale?. ### Response: The Work Group.


Instruction: Who retained final responsibility for the content of the guideline statements and the accompanyingnarrative?

Output: The Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who retained final responsibility for the content of the guideline statements and the accompanyingnarrative?. ### Response: The Work Group.


Instruction: The ERT reviewed draft recommendations andgrades for what?

Output: consistency with the conclusions of the evidencereview

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ERT reviewed draft recommendations andgrades for what?. ### Response: consistency with the conclusions of the evidencereview.


Instruction: Each chapter contains one or more specific recommendations.

Output: Ungraded statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Each chapter contains one or more specific recommendations.. ### Response: Ungraded statements.


Instruction: What is indicated as level 1 or level 2 within each recommendation?

Output: the strength of recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated as level 1 or level 2 within each recommendation?. ### Response: the strength of recommendation.