Instruction: What is unclear if this information can be extrapolated to CKD patients?

Output: the risks associated with the use ofaldosterone antagonists, particularly of hyperkalemia, may beincreased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unclear if this information can be extrapolated to CKD patients?. ### Response: the risks associated with the use ofaldosterone antagonists, particularly of hyperkalemia, may beincreased.


Instruction: What does eplerenone do when added to ACE-I or ARB therapy?

Output: reduction in AER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does eplerenone do when added to ACE-I or ARB therapy?. ### Response: reduction in AER.


Instruction: How many patients with CKD with elevated urine albumin levels were included in the largest relevant RCT available?

Output: 177

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with CKD with elevated urine albumin levels were included in the largest relevant RCT available?. ### Response: 177.


Instruction: What was the dose of enalapril given to 177 patients?

Output: 50 or 100 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the dose of enalapril given to 177 patients?. ### Response: 50 or 100 mg daily.


Instruction: What did the addition of eplerenone to enalapril result in?

Output: areduction in AERs of 40 to 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the addition of eplerenone to enalapril result in?. ### Response: areduction in AERs of 40 to 50%.


Instruction: What was the reduction in AER in the CKD patients receiving analdosterone antagonist in addition to an ACE-I or ARB?

Output: urine albumin excretion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in AER in the CKD patients receiving analdosterone antagonist in addition to an ACE-I or ARB?. ### Response: urine albumin excretion.


Instruction: What is an antagonist in addition to an ACE-I or ARB?

Output: aldosterone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an antagonist in addition to an ACE-I or ARB?. ### Response: aldosterone.


Instruction: Small reductions in GFR and systolic BP have been reported.

Output: 103,107,108

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Small reductions in GFR and systolic BP have been reported.. ### Response: 103,107,108.


Instruction: What is a risk?

Output: Hyperkalemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk?. ### Response: Hyperkalemia.


Instruction: What was not used in the smaller studies?

Output: Thiazide diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not used in the smaller studies?. ### Response: Thiazide diuretics.


Instruction: What was not used in the larger RCT cited above?

Output: Thiazide diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not used in the larger RCT cited above?. ### Response: Thiazide diuretics.


Instruction: What risk was similar among participants receiving enalapril alone and those receiving the combination ofeplerenone and elapron in that trial?

Output: hyperkalemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What risk was similar among participants receiving enalapril alone and those receiving the combination ofeplerenone and elapron in that trial?. ### Response: hyperkalemia.


Instruction: Aldosteroneantagonists have anti-albuminuric, anti-hyperten-sive, and what other effect?

Output: decrease urine albumin excretion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aldosteroneantagonists have anti-albuminuric, anti-hyperten-sive, and what other effect?. ### Response: decrease urine albumin excretion.


Instruction: What are potas-sium-sparing diuretics that may be combined with thiazide?

Output: Aldosterone antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are potas-sium-sparing diuretics that may be combined with thiazide?. ### Response: Aldosterone antagonists.


Instruction: What enhances potassium loss in theurine?

Output: Aldosterone antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What enhances potassium loss in theurine?. ### Response: Aldosterone antagonists.


Instruction: What should be exercised when aldosteroneantagonists are combined with ACE-Is, ARBs or otherpotassium-sparing diuretics?

Output: Great care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be exercised when aldosteroneantagonists are combined with ACE-Is, ARBs or otherpotassium-sparing diuretics?. ### Response: Great care.


Instruction: What is the name of the longitudinal subgroup analysis in SPRINT?

Output: longitudinals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the longitudinal subgroup analysis in SPRINT?. ### Response: longitudinals.


Instruction: What does intensive blood pressure lowering do for kidney tubule injury?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does intensive blood pressure lowering do for kidney tubule injury?. ### Response: Effects.


Instruction: What is kidney tubule injury in CKD?

Output: Effects of intensive bloodpressure lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is kidney tubule injury in CKD?. ### Response: Effects of intensive bloodpressure lowering.


Instruction: What is the name of the longitudinalsubgroup analysis in SPRINT?

Output: Effects of intensive bloodpressure lowering on kidney tubule injury in CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the longitudinalsubgroup analysis in SPRINT?. ### Response: Effects of intensive bloodpressure lowering on kidney tubule injury in CKD.


Instruction: What year did Intern Med publish 169:610–618?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Intern Med publish 169:610–618?. ### Response: 2018.


Instruction: What year was Kidney International published?

Output: 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Kidney International published?. ### Response: 2021.


Instruction: How does aggressive versus moderate glycemic control affect clinical outcomes in diabetic coronary artery bypass graft patients?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does aggressive versus moderate glycemic control affect clinical outcomes in diabetic coronary artery bypass graft patients?. ### Response: Effects.


Instruction: When did Ann Surg. 2011:254:458-463. doi: 10.1097/SLA.0b013e31822c5d78.

Output: Effects of aggressive versus moderate glycemic control on clinical outcomes in diabetic coronary artery bypass graft patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ann Surg. 2011:254:458-463. doi: 10.1097/SLA.0b013e31822c5d78.. ### Response: Effects of aggressive versus moderate glycemic control on clinical outcomes in diabetic coronary artery bypass graft patients.


Instruction: What is the target range for perioperative glucose in patients undergoing coronary intervention?

Output: Strict versus liberal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target range for perioperative glucose in patients undergoing coronary intervention?. ### Response: Strict versus liberal.


Instruction: What is a liberal target range for perioperative glucose in patients undergoing coronary artery bypass grafting?

Output: Strict

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a liberal target range for perioperative glucose in patients undergoing coronary artery bypass grafting?. ### Response: Strict.


Instruction: What is the doi: 10.1016/j.jtcvs.2011.10.070?

Output: J Thorac Cardiovasc Surg. 2012;143:318–325

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1016/j.jtcvs.2011.10.070?. ### Response: J Thorac Cardiovasc Surg. 2012;143:318–325.


Instruction: What is the superiority of moderate control of hyperglyce-mia to tight control in patients undergoing coronary artery bypass graft-ing?

Output: Superiority

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the superiority of moderate control of hyperglyce-mia to tight control in patients undergoing coronary artery bypass graft-ing?. ### Response: Superiority.


Instruction: When did J Thorac Cardiovasc Surg. 2011141:543-551?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Thorac Cardiovasc Surg. 2011141:543-551?. ### Response: 2011.


Instruction: What is the difference between cardiac surgery and paclitaxel-eluting stents in diabetic and non-diabetic patients with left main and/or 3-vessel coronary artery disease?

Output: outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between cardiac surgery and paclitaxel-eluting stents in diabetic and non-diabetic patients with left main and/or 3-vessel coronary artery disease?. ### Response: outcomes.


Instruction: When did J Am Coll Cardiol.55:1067-1075. doi: 10.1016/j.jacc.2009.09.057?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol.55:1067-1075. doi: 10.1016/j.jacc.2009.09.057?. ### Response: 2010.


Instruction: Metabolic syndrome increases the risk of significant coronary artery involvement in patients with what type of disease?

Output: peripheral artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Metabolic syndrome increases the risk of significant coronary artery involvement in patients with what type of disease?. ### Response: peripheral artery disease.


Instruction: Coron Artery Dis. 2006;17:529–532.280

Output: 280

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Coron Artery Dis. 2006;17:529–532.280. ### Response: 280.


Instruction: What type of diabetes affects functional and structural properties of coronary artery bypass conduits?

Output: type 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes affects functional and structural properties of coronary artery bypass conduits?. ### Response: type 2.


Instruction: What is the duration of a long-term serial serial coronary bypass conduit?

Output: 5 to 12 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the duration of a long-term serial serial coronary bypass conduit?. ### Response: 5 to 12 years.


Instruction: How long did serial studies of internal mammary artery and saphenous vein coronary bypass grafts last?

Output: 5 to 12 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did serial studies of internal mammary artery and saphenous vein coronary bypass grafts last?. ### Response: 5 to 12 years.


Instruction: What year did J Thorac Cardiovasc Surg issue 89:248–258?

Output: 1985

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Thorac Cardiovasc Surg issue 89:248–258?. ### Response: 1985.


Instruction: What is the name of the group that studied the long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery?

Output: Department of Veterans Affairs Cooperative Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studied the long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery?. ### Response: Department of Veterans Affairs Cooperative Study.


Instruction: What year was the J Am Coll Cardiol 44:2149-2156?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the J Am Coll Cardiol 44:2149-2156?. ### Response: 2004.


Instruction: What year did J Am Coll Cardiol issue 44:2149-2156?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Am Coll Cardiol issue 44:2149-2156?. ### Response: 2004.


Instruction: What is the name of the study that focuses on Coronary vein graft disease?

Output: V A Cooperative Study Group #207/297/364. Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that focuses on Coronary vein graft disease?. ### Response: V A Cooperative Study Group #207/297/364. Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative Study.


Instruction: When did Can J Cardiol release 25:e57–e62?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Can J Cardiol release 25:e57–e62?. ### Response: 2009.


Instruction: What is the DCCT/EDIC Study Research Group?

Output: Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DCCT/EDIC Study Research Group?. ### Response: Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications.


Instruction: What is intensive diabetes treatment and car-diovascular disease in patients with type 1 diabetes?

Output: Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is intensive diabetes treatment and car-diovascular disease in patients with type 1 diabetes?. ### Response: Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group.


Instruction: Who is Mika Kastarinen?

Output: Kaskel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Mika Kastarinen?. ### Response: Kaskel.


Instruction: Who is Nidiya Lakhani?

Output: Frida L Plavnik

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Nidiya Lakhani?. ### Response: Frida L Plavnik.


Instruction: What is the name of the person who was a member of the Liu family?

Output: Zhi-Hong Liu

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who was a member of the Liu family?. ### Response: Zhi-Hong Liu.


Instruction: Who was the other member of Liu Family?

Output: Zhi-Hong Liu

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the other member of Liu Family?. ### Response: Zhi-Hong Liu.


Instruction: What was the title of the man who played a role in Liu's life?

Output: Gerard London

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the man who played a role in Liu's life?. ### Response: Gerard London.


Instruction: Where was the name given to a person who played the role of a man?

Output: Jose ´Carlos Rodriguez Pe ´rez

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the name given to a person who played the role of a man?. ### Response: Jose ´Carlos Rodriguez Pe ´rez.


Instruction: Morgan; Eugen Mota; Mooppil Nandakumar; Alicia M Neu; Abdou Niang; Javier Nieto; Gregorio T Obrador; AdrianOksa; Marcelo Orias; Alberto Ortiz; Sreejith Parameswaran;Sonia Pasquali; Saime Paydas; Jose Carlos Rodriguez Pe rez;Frida L Plavnik; Claudio Ponticelli; Roberto Pontremoli;Troels Ring; Michael

Output: Sameh Morgan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Morgan; Eugen Mota; Mooppil Nandakumar; Alicia M Neu; Abdou Niang; Javier Nieto; Gregorio T Obrador; AdrianOksa; Marcelo Orias; Alberto Ortiz; Sreejith Parameswaran;Sonia Pasquali; Saime Paydas; Jose Carlos Rodriguez Pe rez;Frida L Plavnik; Claudio Ponticelli; Roberto Pontremoli;Troels Ring; Michael. ### Response: Sameh Morgan.


Instruction: Francisco Rivera; S Adibul Hasan Rizvi; Nicola sRoberto Robles; Michael V Rocco; Guillermo Rosa-Diez;Jaroslav Rosenberger; Luis M Ruilope; Rafael Santamaria; Sergio Santos; Adalbert Schiller; Christine Sethna; Deepak Sharma; Kumar Sharma;Robert Shay; Michael G Shlipak; Alexander Shutov; Neil Smith; Elaine Spalding; Graham

Output: Francisco Rivera; S Adibul Hasan Rizvi; Nicola ´

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Francisco Rivera; S Adibul Hasan Rizvi; Nicola sRoberto Robles; Michael V Rocco; Guillermo Rosa-Diez;Jaroslav Rosenberger; Luis M Ruilope; Rafael Santamaria; Sergio Santos; Adalbert Schiller; Christine Sethna; Deepak Sharma; Kumar Sharma;Robert Shay; Michael G Shlipak; Alexander Shutov; Neil Smith; Elaine Spalding; Graham. ### Response: Francisco Rivera; S Adibul Hasan Rizvi; Nicola ´.


Instruction: What is the name of the person who was a part of the Skov family?

Output: Karin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who was a part of the Skov family?. ### Response: Karin.


Instruction: Who is the author of the book, The Skov Family?

Output: Karin Skov

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the book, The Skov Family?. ### Response: Karin Skov.


Instruction: What was the title of the author, Thesuke Tsukamoto?

Output: Yusuke Tsukamoto

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the author, Thesuke Tsukamoto?. ### Response: Yusuke Tsukamoto.


Instruction: Who did not endorse the content of this report by the above individuals?

Output: Participation in the review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who did not endorse the content of this report by the above individuals?. ### Response: Participation in the review.


Instruction: Who was the author of the report?

Output: io Losito

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of the report?. ### Response: io Losito.


Instruction: Who is a co-chair of the Work Group Co-Chairsacknowledgments?

Output: Gavin J Becker, MD, FRACPDavid C Wheeler, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a co-chair of the Work Group Co-Chairsacknowledgments?. ### Response: Gavin J Becker, MD, FRACPDavid C Wheeler, MD.


Instruction: Who is the author of this report?

Output: io Losito

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of this report?. ### Response: io Losito.


Instruction: What does MAGGIC stand for?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MAGGIC stand for?. ### Response: heart failure.


Instruction: What does the Sociology of Health and Illness say about professional legitimacy claims?

Output: 289 -308 295

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Sociology of Health and Illness say about professional legitimacy claims?. ### Response: 289 -308 295.


Instruction: How many patients from the Swedish heart failure registry were validated?

Output: 51,043

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients from the Swedish heart failure registry were validated?. ### Response: 51,043.


Instruction: What is the European Journal of Heart Failure. 2014; 16(2):173-9 296?

Output: Predicting survival in heart failure: validation of the MAGGIC heart failure risk score in 51,043 patients from the Swedish heart failure registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the European Journal of Heart Failure. 2014; 16(2):173-9 296?. ### Response: Predicting survival in heart failure: validation of the MAGGIC heart failure risk score in 51,043 patients from the Swedish heart failure registry.


Instruction: How does home based telecardiology affect chronic heart failure?

Output: costs and outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does home based telecardiology affect chronic heart failure?. ### Response: costs and outcomes.


Instruction: What is the effect of home based telecardiology on chronic heart failure: costs and outcomes?

Output: Scalvini S, Capomolla S, Zanelli E, Benigno M, Domenighini D, Paletta L et al. Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of home based telecardiology on chronic heart failure: costs and outcomes?. ### Response: Scalvini S, Capomolla S, Zanelli E, Benigno M, Domenighini D, Paletta L et al. Effect.


Instruction: When did the Journal of Telemedicine and Telecare publish?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Journal of Telemedicine and Telecare publish?. ### Response: 2005.


Instruction: What is the 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines?

Output: Antithrombotic and thrombolytic therapy for valvular dis-ease: antithrombotic therapy and prevention of throm bosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines?. ### Response: Antithrombotic and thrombolytic therapy for valvular dis-ease: antithrombotic therapy and prevention of throm bosis.


Instruction: What does Bates do for valvular dis-ease?

Output: antithrombotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Bates do for valvular dis-ease?. ### Response: antithrombotic therapy.


Instruction: What is the name of the 9th ed of the American College of Chest Physi-cians evidence-based clinical practice guidelines?

Output: American College of Chest Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 9th ed of the American College of Chest Physi-cians evidence-based clinical practice guidelines?. ### Response: American College of Chest Physicians.


Instruction: What does thrombophilia, antithrombotic therapy, and pregnancy mean?

Output: prevention of thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does thrombophilia, antithrombotic therapy, and pregnancy mean?. ### Response: prevention of thrombosis.


Instruction: What are evidence-based clinical practice guidelines?

Output: antithrombotic therapy and prevention of thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are evidence-based clinical practice guidelines?. ### Response: antithrombotic therapy and prevention of thrombosis.


Instruction: What are patient values and pref-erences in decision making for antithrombotic therapy?

Output: a systematic review: antithrombotic therapy and preven tion of thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patient values and pref-erences in decision making for antithrombotic therapy?. ### Response: a systematic review: antithrombotic therapy and preven tion of thrombosis.


Instruction: Who wrote the 9th ed?

Output: Guyatt GH, Norris SL, Schulman S

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the 9th ed?. ### Response: Guyatt GH, Norris SL, Schulman S.


Instruction: What is the 9th ed of the American College of Chest Physi-cians?

Output: evidence-based clinical practice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 9th ed of the American College of Chest Physi-cians?. ### Response: evidence-based clinical practice guidelines.


Instruction: What are the evidence-based clinical practice guidelines for?

Output: thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the evidence-based clinical practice guidelines for?. ### Response: thrombosis.


Instruction: What is the 9th ed of antithrombotic therapy and prevention of thrombosis called?

Output: American College of Chest Physi-cians evidence-based clinical practice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 9th ed of antithrombotic therapy and prevention of thrombosis called?. ### Response: American College of Chest Physi-cians evidence-based clinical practice guidelines.


Instruction: What are the evidence-based clinical practice guidelines of the American College of Chest Physicians?

Output: guide-lines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the evidence-based clinical practice guidelines of the American College of Chest Physicians?. ### Response: guide-lines.


Instruction: How many strokes were there between 2068 and 2072 in 2009?

Output: 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there between 2068 and 2072 in 2009?. ### Response: 40.


Instruction: How many risk stratifi cation schemes are there to predict stroke in patients with nonvalvular atrial fibrillation?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many risk stratifi cation schemes are there to predict stroke in patients with nonvalvular atrial fibrillation?. ### Response: 12.


Instruction: Atrial fibrillation. Stroke. 2008 ; 39 ( 6 ): 1901 - 1910. 13. Lévy S, Camm AJ, Saksena S.

Output: Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation. Stroke. 2008 ; 39 ( 6 ): 1901 - 1910. 13. Lévy S, Camm AJ, Saksena S.. ### Response: Stroke.


Instruction: What is the working group on arrhythmias called?

Output: Working Group on Arrhythmias, Working Group on Cardiac Pacing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the working group on arrhythmias called?. ### Response: Working Group on Arrhythmias, Working Group on Cardiac Pacing.


Instruction: What are the working groups on cardiac pacing of the European Society of Cardiology and the North American Society of Pacing?

Output: Working Group on Arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the working groups on cardiac pacing of the European Society of Cardiology and the North American Society of Pacing?. ### Response: Working Group on Arrhythmias.


Instruction: What is a collaborative project of the Working Group on Arrhythmias?

Output: International consensus on nomenclature and classiﬁ  cation of atrial ﬁ  brillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a collaborative project of the Working Group on Arrhythmias?. ### Response: International consensus on nomenclature and classiﬁ  cation of atrial ﬁ  brillation.


Instruction: What is the working group on Cardiac Pacing of the Euro-pean Society of Cardiology?

Output: Working Group on Arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the working group on Cardiac Pacing of the Euro-pean Society of Cardiology?. ### Response: Working Group on Arrhythmias.


Instruction: What is the name of the American College of Chest Physicians?

Output: American College of Chest Physi-cians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the American College of Chest Physicians?. ### Response: American College of Chest Physi-cians.


Instruction: What was Kimberly Henricks name?

Output: American College of Chest Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was Kimberly Henricks name?. ### Response: American College of Chest Physicians.


Instruction: • take into account the lengt h of time since t he suspect ed A CS when int erpreting the tr oponin le vel?

Output: Take the ECG as soon as possible, but do not dela y transf er to hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: • take into account the lengt h of time since t he suspect ed A CS when int erpreting the tr oponin le vel?. ### Response: Take the ECG as soon as possible, but do not dela y transf er to hospital.


Instruction: Use what to decide whet her r eferral is neccessar y and how urgent?

Output: clinical judgement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Use what to decide whet her r eferral is neccessar y and how urgent?. ### Response: clinical judgement.


Instruction: What should people do if they have a recent (confirmed or suspect ed) A CS and develop fur ther chest pain?

Output: Refer people t o hospital as an emer gency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should people do if they have a recent (confirmed or suspect ed) A CS and develop fur ther chest pain?. ### Response: Refer people t o hospital as an emer gency.


Instruction: What should be referred to as an emer gency if t hey have?

Output: Refer people t o hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be referred to as an emer gency if t hey have?. ### Response: Refer people t o hospital.


Instruction: What is suspect ed, star t management immediat ely in t he or der appr opriat e to the cir cumstances?

Output: A CS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is suspect ed, star t management immediat ely in t he or der appr opriat e to the cir cumstances?. ### Response: A CS.


Instruction: What is a resting 12-lead ECG?

Output: sho wing r egional ST -segment depr ession or deep T wave inversion suggestiv e of a NSTEMI or unstable angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a resting 12-lead ECG?. ### Response: sho wing r egional ST -segment depr ession or deep T wave inversion suggestiv e of a NSTEMI or unstable angina.


Instruction: If an A CS is not suspected, consider what ot her causes?

Output: chest pain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If an A CS is not suspected, consider what ot her causes?. ### Response: chest pain.


Instruction: What are some of the r ecommendations 1.2.6.5, 1.2.6.7, and 1.2.6.8?

Output: chest pain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the r ecommendations 1.2.6.5, 1.2.6.7, and 1.2.6.8?. ### Response: chest pain.


Instruction: When people ar e referred, what should be done?

Output: send t he result s to hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When people ar e referred, what should be done?. ### Response: send t he result s to hospital.


Instruction: What should people do if they are referred?

Output: send t he result s to hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should people do if they are referred?. ### Response: send t he result s to hospital.


Instruction: What should not dela y transf er to hospital?

Output: Recording and sending t he ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not dela y transf er to hospital?. ### Response: Recording and sending t he ECG.


Instruction: How should people wit h a referred ECG bef ore they arriv e?

Output: send t he result s to hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should people wit h a referred ECG bef ore they arriv e?. ### Response: send t he result s to hospital.


Instruction: What does LBBB stand for?

Output: new left bundle branch block

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LBBB stand for?. ### Response: new left bundle branch block.


Instruction: How long does it take to make a diagnosis?

Output: 1.2.1.11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to make a diagnosis?. ### Response: 1.2.1.11.


Instruction: What is the NICE guideline for people with a resting 12-lead ECG sho wing r egional ST -segment depr ssion or deep T wave inversion suggestiv?

Output: acut e cor onar y syndr omes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NICE guideline for people with a resting 12-lead ECG sho wing r egional ST -segment depr ssion or deep T wave inversion suggestiv?. ### Response: acut e cor onar y syndr omes.


Instruction: What is a ST -segment depr ession or deep T wave inversion suggestiv e of?

Output: a NSTEMI or unstable angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a ST -segment depr ession or deep T wave inversion suggestiv e of?. ### Response: a NSTEMI or unstable angina.


Instruction: Until a firm diagnosis is made, what is suggestive of a NSTEMI or unstable angina?

Output: deep T wave inversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Until a firm diagnosis is made, what is suggestive of a NSTEMI or unstable angina?. ### Response: deep T wave inversion.


Instruction: What is the name of the book that describes recent onset chest pain of suspect ed car diac origin?

Output: CG95

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes recent onset chest pain of suspect ed car diac origin?. ### Response: CG95.


Instruction: When will all right s reserved?

Output: 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will all right s reserved?. ### Response: 2022.


Instruction: What was the last updat ed 30 No vember 2016Page 9of 33

Output: Notice of right s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the last updat ed 30 No vember 2016Page 9of 33. ### Response: Notice of right s.


Instruction: What are the consequences for coronary artery disease and all-cause mortality?

Output: Statins in familial hyper -cholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the consequences for coronary artery disease and all-cause mortality?. ### Response: Statins in familial hyper -cholesterolemia.


Instruction: What is the name of the journal that studies the effects of statins in familial hyper cholesterolemia?

Output: BMJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the effects of statins in familial hyper cholesterolemia?. ### Response: BMJ.


Instruction: Who is the author of the study?

Output: Sniderman AD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study?. ### Response: Sniderman AD.


Instruction: When was the J Am Coll Cardiol 2016 68:252-60?

Output: 2016;67:2578–89

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 2016 68:252-60?. ### Response: 2016;67:2578–89.


Instruction: What is the clini-cal utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholestrolemia?

Output: Diagnostic yield

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clini-cal utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholestrolemia?. ### Response: Diagnostic yield.


Instruction: What was the J Am Coll Cardiol. 2016;67:2578–89?

Output: Diagnostic yield and clini-cal utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol. 2016;67:2578–89?. ### Response: Diagnostic yield and clini-cal utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia.


Instruction: Nanchen D, Gencer B, Muller O, et al. Prognosis of patients with what?

Output: familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nanchen D, Gencer B, Muller O, et al. Prognosis of patients with what?. ### Response: familial hypercholesterolemia.


Instruction: What is the long-term risk of atheroscle-rotic cardiovascular disease in US adults with the familial hypercho-lesterolemia phenotype?

Output: 134:9–19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term risk of atheroscle-rotic cardiovascular disease in US adults with the familial hypercho-lesterolemia phenotype?. ### Response: 134:9–19.


Instruction: What does Shepherd J, Cobbe SM, Ford I, et al. do with pravastatin?

Output: Prevention of coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Shepherd J, Cobbe SM, Ford I, et al. do with pravastatin?. ### Response: Prevention of coronary heart disease.


Instruction: What is pravastatin used for in men with hypercholesterolemia?

Output: Prevention of coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is pravastatin used for in men with hypercholesterolemia?. ### Response: Prevention of coronary heart disease.


Instruction: When did the West of Scotland Coronary Prevention Study Group publish?

Output: 1995

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the West of Scotland Coronary Prevention Study Group publish?. ### Response: 1995.


Instruction: What is the name of the long term cohort study that evaluated the efficacy of statins?

Output: BioImage Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the long term cohort study that evaluated the efficacy of statins?. ### Response: BioImage Study.


Instruction: What is a simple disease-guided approach to personalize ACC/AHA-recommended statin allocation in elderly people?

Output: the BioImage Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simple disease-guided approach to personalize ACC/AHA-recommended statin allocation in elderly people?. ### Response: the BioImage Study.


Instruction: What is the BioImage Study?

Output: A simple disease-guided approach to personalize ACC/AHA-recommended statin allocation in elderly people

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BioImage Study?. ### Response: A simple disease-guided approach to personalize ACC/AHA-recommended statin allocation in elderly people.


Instruction: How long did the Bruneck study last?

Output: 15-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Bruneck study last?. ### Response: 15-year.


Instruction: What is the name of the study that evaluated cardiovascular risk with lipoprotein(a)?

Output: Bruneck Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated cardiovascular risk with lipoprotein(a)?. ### Response: Bruneck Study.


Instruction: What does MESA stand for?

Output: Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MESA stand for?. ### Response: Multi-Ethnic Study of Atherosclerosis.


Instruction: What is the name of the multi-ethnic study of atherosclerosis?

Output: MESA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-ethnic study of atherosclerosis?. ### Response: MESA.


Instruction: When was the J Am Coll Cardiol 201666:1657-68?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 201666:1657-68?. ### Response: 2015.


Instruction: What are emerging lipid-lowering agents?

Output: guidelines and for the prescription

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are emerging lipid-lowering agents?. ### Response: guidelines and for the prescription.


Instruction: What is the Eur Heart J. 2017:37:1373-9.

Output: prescription of emerging lipid-lowering agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Eur Heart J. 2017:37:1373-9.. ### Response: prescription of emerging lipid-lowering agents.


Instruction: What does age have to do with cardiovascular risk in older adults?

Output: coronary artery calcium score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does age have to do with cardiovascular risk in older adults?. ### Response: coronary artery calcium score.


Instruction: What is the name of the population-based study?

Output: Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the population-based study?. ### Response: Multi-Ethnic Study of Atherosclerosis.


Instruction: What does the Multi-Ethnic Study of Atherosclerosis measure in individuals with type 2 diabetes and metabolic syndrome?

Output: Coronary artery calcium score for long-term risk classification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Multi-Ethnic Study of Atherosclerosis measure in individuals with type 2 diabetes and metabolic syndrome?. ### Response: Coronary artery calcium score for long-term risk classification.


Instruction: What is the phenotype of severe hypercholesterolemia?

Output: clinical diagnosis, management, and emerging thera-pies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the phenotype of severe hypercholesterolemia?. ### Response: clinical diagnosis, management, and emerging thera-pies.


Instruction: What is a meta-analysis of low-dose cholesterol?

Output: Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol. 2015;66:1657–68. S4.3-29. Ridker PM, Mora S, Rose L, et al. Percent reduction in LDL choles-terol following high-intensity statin therapy: potential implications for guidelines and for the prescription of emerging lipid-lowering agents. Eur Heart J. 2016;37:1373–9. S4.3-30. Yano Y, O’Donnell CJ, Kuller L, et al. Association of coronary artery calcium score vs age with cardiovascular risk in older adults: an analysis of pooled population-based studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of low-dose cholesterol?. ### Response: Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol. 2015;66:1657–68. S4.3-29. Ridker PM, Mora S, Rose L, et al. Percent reduction in LDL choles-terol following high-intensity statin therapy: potential implications for guidelines and for the prescription of emerging lipid-lowering agents. Eur Heart J. 2016;37:1373–9. S4.3-30. Yano Y, O’Donnell CJ, Kuller L, et al. Association of coronary artery calcium score vs age with cardiovascular risk in older adults: an analysis of pooled population-based studies.


Instruction: What is Darren Green Consultant Nephrologist and Acute Physician?

Output: Salford Royal Foundation Trust

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Darren Green Consultant Nephrologist and Acute Physician?. ### Response: Salford Royal Foundation Trust.


Instruction: What is Hasnain Dalal Senior Clinical Researcher, Royal Cornwall?

Output: Honorary Clinical Associate Professor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Hasnain Dalal Senior Clinical Researcher, Royal Cornwall?. ### Response: Honorary Clinical Associate Professor.


Instruction: Hasnain Dalal Senior Clinical Researcher, Royal Cornwall Hospitals?

Output: Hasnain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hasnain Dalal Senior Clinical Researcher, Royal Cornwall Hospitals?. ### Response: Hasnain.


Instruction: Suzanne Kite Palliative Care Physician Kath Measures Clinical Specialist Physiotherapist in Cardiology Simon Corbett Consul tant Cardiologist, University Hospital Southampton

Output: 978 -1-4731 -3093-7 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Suzanne Kite Palliative Care Physician Kath Measures Clinical Specialist Physiotherapist in Cardiology Simon Corbett Consul tant Cardiologist, University Hospital Southampton. ### Response: 978 -1-4731 -3093-7 12.


Instruction: Who is Rod Taylor Professor in Health Services Research?

Output: Director of Exeter Clinical Trials Unit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Rod Taylor Professor in Health Services Research?. ### Response: Director of Exeter Clinical Trials Unit.


Instruction: Who is Martin Cowie Honorary Consultant?

Output: Cardiologist, Royal Brompton & Harefield NHS Trust

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Martin Cowie Honorary Consultant?. ### Response: Cardiologist, Royal Brompton & Harefield NHS Trust.


Instruction: What is the name of the reference list for Chronic Heart Failure?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the reference list for Chronic Heart Failure?. ### Response: NICE 2018.


Instruction: What type of peptide is used in bedside tests in the treatment of chronic heart failure?

Output: natriuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of peptide is used in bedside tests in the treatment of chronic heart failure?. ### Response: natriuretic.


Instruction: Bedside tests of B -type natriuretic peptide in the diagnosis of left ventricular diastolic d ysfunction in hypertensive patients.

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bedside tests of B -type natriuretic peptide in the diagnosis of left ventricular diastolic d ysfunction in hypertensive patients.. ### Response: Chronic Heart Failure.


Instruction: European Journal of Heart Failure. 2005; 7(1):75 -79 367.

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: European Journal of Heart Failure. 2005; 7(1):75 -79 367.. ### Response: Chronic Heart Failure.


Instruction: What is PROTECT?

Output: ProBNP Outpatient Tailored Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PROTECT?. ### Response: ProBNP Outpatient Tailored Chronic Heart Failure.


Instruction: What is the name of the study that helped improve structural and functional echocardiographic parameters?

Output: ProBNP Outpatient Tailored Chronic Heart Failure (PROTECT) study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that helped improve structural and functional echocardiographic parameters?. ### Response: ProBNP Outpatient Tailored Chronic Heart Failure (PROTECT) study.


Instruction: How many intravenous iron preparations were used in a UK anaemia clinic?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many intravenous iron preparations were used in a UK anaemia clinic?. ### Response: two.


Instruction: What is the name of the computer program used by WinBUGS?

Output: WinBUGS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the computer program used by WinBUGS?. ### Response: WinBUGS.


Instruction: What does WinBUGS stand for?

Output: Computer programme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does WinBUGS stand for?. ### Response: Computer programme.


Instruction: What is the name of the computer program that runs on WinBugs?

Output: WinBUGS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the computer program that runs on WinBugs?. ### Response: WinBUGS.


Instruction: Where is the MR C Biostatistics Unit located?

Output: University of Cambridge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the MR C Biostatistics Unit located?. ### Response: University of Cambridge.


Instruction: What does Needs of caregivers in heart failure management: A qualitative study?

Output: self -care behaviou rs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Needs of caregivers in heart failure management: A qualitative study?. ### Response: self -care behaviou rs.


Instruction: Chronic Illness. 2015; 11(4):304 -319 371.

Output: heart failure management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chronic Illness. 2015; 11(4):304 -319 371.. ### Response: heart failure management.


Instruction: Heart Failure in Young Adults Is Associated With High Mortality: A Contemporary Population-Level Analysis.

Output: Wong CM, Hawkins NM, Ezekowitz JA, Jhund PS, Savu A, MacDonald MR et al. Heart Failure in Young Adults I s Associated With High Mortality: A Contemporary Population -Level Analysis. Canadian Journal of Cardiology. 2017; 33(11):1472 -1477  372

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Heart Failure in Young Adults Is Associated With High Mortality: A Contemporary Population-Level Analysis.. ### Response: Wong CM, Hawkins NM, Ezekowitz JA, Jhund PS, Savu A, MacDonald MR et al. Heart Failure in Young Adults I s Associated With High Mortality: A Contemporary Population -Level Analysis. Canadian Journal of Cardiology. 2017; 33(11):1472 -1477  372.


Instruction: With High Mortality: A Contemporary Population-Level Analysis. Canadian Journal of Cardiology. 2017; 33(11):1472 -1477 372.

Output: Heart Failure in Young Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: With High Mortality: A Contemporary Population-Level Analysis. Canadian Journal of Cardiology. 2017; 33(11):1472 -1477 372.. ### Response: Heart Failure in Young Adults.


Instruction: Telehome monitoring in patients with cardiac disease who are at high risk of readmission. 2008. 37(1):36 -45.

Output: Woodend AK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Telehome monitoring in patients with cardiac disease who are at high risk of readmission. 2008. 37(1):36 -45.. ### Response: Woodend AK.


Instruction: What is the risk of readmission in patients with left ventricular dysfunction?

Output: 372.  Woodend AK, Sherrard H, Fraser M, Stuewe L, Cheung T, Struthers C. Telehome monitoring in patients with cardiac disease who are at high risk of readmission. Heart and Lung. 2008; 37(1):36 -45 373

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of readmission in patients with left ventricular dysfunction?. ### Response: 372.  Woodend AK, Sherrard H, Fraser M, Stuewe L, Cheung T, Struthers C. Telehome monitoring in patients with cardiac disease who are at high risk of readmission. Heart and Lung. 2008; 37(1):36 -45 373.


Instruction: What was the journal of the Chinese Medical Association 69(5):218 -23 374?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the journal of the Chinese Medical Association 69(5):218 -23 374?. ### Response: 2006.


Instruction: What year did the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines publish a Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines publish a Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure?. ### Response: 2017.


Instruction: What is the name of the Task Force on Clinical Practice Guidelines?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Clinical Practice Guidelines?. ### Response: American College of Cardiology/American Heart Association.


Instruction: What are the names of the organizations involved in the Heart Failure Society of America?

Output: American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the organizations involved in the Heart Failure Society of America?. ### Response: American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Instruction: When was the last issue of Circulation published?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of Circulation published?. ### Response: 2017.


Instruction: What is the relationship between brain natriuretic peptide and heart function in patients with chronic kidney disease?

Output: Relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between brain natriuretic peptide and heart function in patients with chronic kidney disease?. ### Response: Relationship.


Instruction: What journal published a study on heart failure patients in iran in 2008?

Output: Korean Journal of Internal Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What journal published a study on heart failure patients in iran in 2008?. ### Response: Korean Journal of Internal Medicine.


Instruction: What is the effect on self -care behaviours?

Output: A supportive -educational intervention for heart failure patients in iran

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect on self -care behaviours?. ### Response: A supportive -educational intervention for heart failure patients in iran.


Instruction: What was the 2013:492729 377?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2013:492729 377?. ### Response: 2013.


Instruction: How long did the GUSTO IV-ACS trial last?

Output: one-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the GUSTO IV-ACS trial last?. ### Response: one-year.


Instruction: What is the name of the trial that showed one-year survival?

Output: GUSTO IV-ACS (Global Use of Strategies To Open Occluded Coronary Arteries IV–Acute Coronary Syndrome) Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that showed one-year survival?. ### Response: GUSTO IV-ACS (Global Use of Strategies To Open Occluded Coronary Arteries IV–Acute Coronary Syndrome) Trial.


Instruction: When was the Circulation.107:437–42?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.107:437–42?. ### Response: 2003.


Instruction: What are bleeding events after treatment of acute coronary syndrome?

Output: cardiac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are bleeding events after treatment of acute coronary syndrome?. ### Response: cardiac.


Instruction: What is an unintended consequence of enteric coating aspirin?

Output: is-tance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an unintended consequence of enteric coating aspirin?. ### Response: is-tance.


Instruction: Who wrote a systematic review of the literature?

Output: Berger JS, Sallum RH, Katona B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote a systematic review of the literature?. ### Response: Berger JS, Sallum RH, Katona B.


Instruction: What drug was compared with clopidogrel in patients with planned percu-taneous coronary intervention?

Output: Prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was compared with clopidogrel in patients with planned percu-taneous coronary intervention?. ### Response: Prasugrel.


Instruction: What is the name of the study that compared prasugrel with a high loading-and-maintenance-dose clopidogral?

Output: Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compared prasugrel with a high loading-and-maintenance-dose clopidogral?. ### Response: Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial.


Instruction: When was the Circulation. 2007;116:2923-32?

Output: 301

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation. 2007;116:2923-32?. ### Response: 301.


Instruction: What is Plaivx?

Output: Bristol-Myers Squibb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Plaivx?. ### Response: Bristol-Myers Squibb.


Instruction: What is Prasugrel versus clopi-dogrel in patients with acute coronary syndromes?

Output: without revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Prasugrel versus clopi-dogrel in patients with acute coronary syndromes?. ### Response: without revascularization.


Instruction: How many trials were there in 2007?

Output: 303

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many trials were there in 2007?. ### Response: 303.


Instruction: Prasugrel versus clopidogrel for acute coronary syndromes without revascularization?

Output: N Engl J Med. 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prasugrel versus clopidogrel for acute coronary syndromes without revascularization?. ### Response: N Engl J Med. 2012.


Instruction: What is prasu-grel used for in non-ST-segment elevation?

Output: acute coronary syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is prasu-grel used for in non-ST-segment elevation?. ### Response: acute coronary syndromes.


Instruction: What is clopidogrel and ticagrelor?

Output: P2Y12 receptor antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel and ticagrelor?. ### Response: P2Y12 receptor antagonists.


Instruction: What is PLATELEt inhibition and patient outcomes?

Output: Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PLATELEt inhibition and patient outcomes?. ### Response: Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial.


Instruction: When did AstraZeneca release the Brilinta REMS document?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did AstraZeneca release the Brilinta REMS document?. ### Response: 2011.


Instruction: What is the name of the meta-analysis of randomized trials of Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention?

Output: a meta-analysis of randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of randomized trials of Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention?. ### Response: a meta-analysis of randomized trials.


Instruction: What does Stone GW, Bertrand ME, Moses JW, et al. use vs deferred selective use of glycoprotein?

Output: Routine upstream initiation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Stone GW, Bertrand ME, Moses JW, et al. use vs deferred selective use of glycoprotein?. ### Response: Routine upstream initiation.


Instruction: What is the ACUITY Timing trial?

Output: Routine upstream initiation vs deferred selective use of glycoprotein IIb/IIIa inhibitors in acute coro-nary syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACUITY Timing trial?. ### Response: Routine upstream initiation vs deferred selective use of glycoprotein IIb/IIIa inhibitors in acute coro-nary syndromes.


Instruction: What is enoxaparin vs unfrac-tionated heparin?

Output: Enoxaparin vs unfrac-tionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin vs unfrac-tionated heparin?. ### Response: Enoxaparin vs unfrac-tionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy.


Instruction: What was the primary outcome of the SYNERGY randomized trial?

Output: Enoxaparin vs unfrac-tionated heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome of the SYNERGY randomized trial?. ### Response: Enoxaparin vs unfrac-tionated heparin.


Instruction: What did Stone GW, McLaurin BT, Cox DA, et al. use for patients with acute coronary syndromes?

Output: Bivalirudin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Stone GW, McLaurin BT, Cox DA, et al. use for patients with acute coronary syndromes?. ### Response: Bivalirudin.


Instruction: When did N Engl J Med issue 355:2203-16?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 355:2203-16?. ### Response: 2006.


Instruction: What is a subgroup analysis from the Acute Catheterization and Urgent Intervention Triage strategy (ACUITY) trial?

Output: Bivalirudin in patients with acute coronary syndromes undergoing percutaneous coronary interven-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a subgroup analysis from the Acute Catheterization and Urgent Intervention Triage strategy (ACUITY) trial?. ### Response: Bivalirudin in patients with acute coronary syndromes undergoing percutaneous coronary interven-tion.


Instruction: What is the ACUITY strategy?

Output: Acute Catheterization and Urgent Intervention Triage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACUITY strategy?. ### Response: Acute Catheterization and Urgent Intervention Triage.


Instruction: Who is labored with the Society for Cardiovascular Angiography and Interven-tions?

Output: Japanese Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is labored with the Society for Cardiovascular Angiography and Interven-tions?. ### Response: Japanese Society of Echocardiography.


Instruction: What is the Japanese Society of Echocardiography?

Output: Society for Cardiovascular Angiography and Interven-tions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Japanese Society of Echocardiography?. ### Response: Society for Cardiovascular Angiography and Interven-tions.


Instruction: How is multimodality imaging guidance for percutaneous paravalvular leak closure?

Output: Insights from the multi-centre FFPP register

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is multimodality imaging guidance for percutaneous paravalvular leak closure?. ### Response: Insights from the multi-centre FFPP register.


Instruction: Insights from the multi-centre FFPP register.

Output: Multimodality imaging guidance for percutaneous paravalvular leak closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Insights from the multi-centre FFPP register.. ### Response: Multimodality imaging guidance for percutaneous paravalvular leak closure.


Instruction: What is the name of the instrument used to evaluate the success of percutaneous transcatheter closure of mitral paravalvular leaks?

Output: real-time three-dimensional transesophageal echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the instrument used to evaluate the success of percutaneous transcatheter closure of mitral paravalvular leaks?. ### Response: real-time three-dimensional transesophageal echocardiography.


Instruction: What year did J Am Soc Echocardiogr. 2010:23:26–32?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Am Soc Echocardiogr. 2010:23:26–32?. ### Response: 2019.


Instruction: What year did Soc Echocardiogr. 2010:23:26–32?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Soc Echocardiogr. 2010:23:26–32?. ### Response: 2019.


Instruction: What was left untreated at the time of aortic valve replacement?

Output: mitral regurgita-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was left untreated at the time of aortic valve replacement?. ### Response: mitral regurgita-tion.


Instruction: What is the name of the study that describes clinical trial principles and endpoint definitions for paravalvular leaks in surgical prosthesis?

Output: an expert state-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that describes clinical trial principles and endpoint definitions for paravalvular leaks in surgical prosthesis?. ### Response: an expert state-ment.


Instruction: What are the recommendations for image acquisition and display using EAE/ASE?

Output: three-dimensional echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for image acquisition and display using EAE/ASE?. ### Response: three-dimensional echocardiography.


Instruction: What are the recommendations for image acquisition and display using three-dimensional echocardiography?

Output: EAE/ASE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for image acquisition and display using three-dimensional echocardiography?. ### Response: EAE/ASE.


Instruction: When was the J Am Soc Echocardiogr. 2012:25:3–46?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Soc Echocardiogr. 2012:25:3–46?. ### Response: 2012.


Instruction: What is the role of paravalvular leak closure under intracardiac echocardiographic guidance?

Output: improved midterm survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of paravalvular leak closure under intracardiac echocardiographic guidance?. ### Response: improved midterm survival.


Instruction: What is a benchmark for transcatheter valve-in-valve procedures?

Output: Contemporary outcomes of re-peat aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a benchmark for transcatheter valve-in-valve procedures?. ### Response: Contemporary outcomes of re-peat aortic valve replacement.


Instruction: What are the early and late results of the surgical correction of?

Output: cardiac prosthetic paravalvular leaks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the early and late results of the surgical correction of?. ### Response: cardiac prosthetic paravalvular leaks.


Instruction: What is the risk of reoperation for mitral valve replacement in patients 65 years old?

Output: Significant mitral regurgita-tion left untreated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of reoperation for mitral valve replacement in patients 65 years old?. ### Response: Significant mitral regurgita-tion left untreated.


Instruction: What is the risk of reoperation for mitral bioprosthesis dysfunction?

Output: 4. Jaussaud N, Gariboldi V, Grisoli D, et al. Risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of reoperation for mitral bioprosthesis dysfunction?. ### Response: 4. Jaussaud N, Gariboldi V, Grisoli D, et al. Risk.


Instruction: What are the outcomes of percutaneous repair of paravalvular prosthetic regurgitation in 115 patients?

Output: acute and 30-day outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes of percutaneous repair of paravalvular prosthetic regurgitation in 115 patients?. ### Response: acute and 30-day outcomes.


Instruction: What year did Circ Cardiovasc Interv. 2011:4:314–21?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circ Cardiovasc Interv. 2011:4:314–21?. ### Response: 2011.


Instruction: What is the name of the surgeon who performed long-term follow-up of percuta-neous repair of paravalvular prosthetic regurgitation?

Output: Sorajja P , Cabalka AK, Hagler DJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the surgeon who performed long-term follow-up of percuta-neous repair of paravalvular prosthetic regurgitation?. ### Response: Sorajja P , Cabalka AK, Hagler DJ.


Instruction: What are the long-term outcomes of mitral paravalvular leak management?

Output: Transcatheter and surgical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the long-term outcomes of mitral paravalvular leak management?. ### Response: Transcatheter and surgical.


Instruction: What is the JACC Cardiovasc Interv. 2017;10:1946–56?

Output: Transcatheter and surgical manage-ment of mitral paravalvular leak: long-term outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JACC Cardiovasc Interv. 2017;10:1946–56?. ### Response: Transcatheter and surgical manage-ment of mitral paravalvular leak: long-term outcomes.


Instruction: How is successful percutaneous mitral Para-Valvular Leak closure associated with midterm survival?

Output: improved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is successful percutaneous mitral Para-Valvular Leak closure associated with midterm survival?. ### Response: improved.


Instruction: What is the name of the 2021 guideline for the secondary prevention of isschemic StrokeStates?

Output: GUIDELINESKleindorfer et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2021 guideline for the secondary prevention of isschemic StrokeStates?. ### Response: GUIDELINESKleindorfer et al.


Instruction: Prediabetes has the same pathophysiology as what other disease?

Output: T2D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prediabetes has the same pathophysiology as what other disease?. ### Response: T2D.


Instruction: What is associated with lower plasma glucose than T2D?

Output: Prediabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with lower plasma glucose than T2D?. ### Response: Prediabetes.


Instruction: What is the prevalence of diagnosed diabetes among US adults?

Output: 9%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of diagnosed diabetes among US adults?. ### Response: 9%..


Instruction: Prediabetes and diabetes are asso-ciated with increased risk for first ischemic stroke (RR, 1.5%–3.7% for diabetes)?

Output: 249

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prediabetes and diabetes are asso-ciated with increased risk for first ischemic stroke (RR, 1.5%–3.7% for diabetes)?. ### Response: 249.


Instruction: What is present in 30% of patients with acute ischemia stroke255 and is associated with higher risk for recurrence256?

Output: Prediabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is present in 30% of patients with acute ischemia stroke255 and is associated with higher risk for recurrence256?. ### Response: Prediabetes.


Instruction: T2D is present in  30% of patients with what type of stroke?

Output: ischemic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: T2D is present in  30% of patients with what type of stroke?. ### Response: ischemic.


Instruction: What is associated with increased risk for recurrence?

Output: Prediabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with increased risk for recurrence?. ### Response: Prediabetes.


Instruction: What is associated with increased risk for recur-ence?

Output: T2D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with increased risk for recur-ence?. ### Response: T2D.


Instruction: How can remission of established T2D be achieved?

Output: by weight loss

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can remission of established T2D be achieved?. ### Response: by weight loss.


Instruction: What can be achieved by weight loss?

Output: 2D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be achieved by weight loss?. ### Response: 2D.


Instruction: How many classes of glucose-lowering medications can reduce risk for MACEs in patients with T2D and established ath-erosclerotic vascular disease?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many classes of glucose-lowering medications can reduce risk for MACEs in patients with T2D and established ath-erosclerotic vascular disease?. ### Response: 3.


Instruction: What is GLP-1 receptor agonist?

Output: glucagon-like protein 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GLP-1 receptor agonist?. ### Response: glucagon-like protein 1.


Instruction: What is the name of the GLP-1 receptor agonist?

Output: glucagon-like protein 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the GLP-1 receptor agonist?. ### Response: glucagon-like protein 1.


Instruction: What is another name for the sodium-glucose cotrans-porter 2 inhibitor?

Output: thiazolidinediones, glucagon-like protein 1 (GLP-1) receptor agonist, and sodium-glucose cotrans-porter 2 inhibitor. Unlike the data for the thiazolidinedi-one pioglitazone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the sodium-glucose cotrans-porter 2 inhibitor?. ### Response: thiazolidinediones, glucagon-like protein 1 (GLP-1) receptor agonist, and sodium-glucose cotrans-porter 2 inhibitor. Unlike the data for the thiazolidinedi-one pioglitazone.


Instruction: In the cardiovascular outcome trials, what does not suggest a specific effect on stroke?

Output: sodium-glucose cotransporter 2 inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the cardiovascular outcome trials, what does not suggest a specific effect on stroke?. ### Response: sodium-glucose cotransporter 2 inhibitors.


Instruction: What type of diabetes has been shown to reduce risk for microvascular complications?

Output: type 1 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes has been shown to reduce risk for microvascular complications?. ### Response: type 1 diabetes.


Instruction: What is the DCCT?

Output: Diabetes Control and Complication Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DCCT?. ### Response: Diabetes Control and Complication Trial.


Instruction: What type of diabetes trial enrolled patients between 13 and 39 years of age?

Output: Diabetes Control and Complication Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes trial enrolled patients between 13 and 39 years of age?. ### Response: Diabetes Control and Complication Trial.


Instruction: How were the participants randomized?

Output: conventional glucose control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the participants randomized?. ### Response: conventional glucose control.


Instruction: What was the goal of the DCCT?

Output: avoid symptoms of hyperglycemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the goal of the DCCT?. ### Response: avoid symptoms of hyperglycemia.


Instruction: How long did intensive control delay the onset or pro-gression of nephropathy, retinopathy, and neuropa-thy?

Output: 6.5 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did intensive control delay the onset or pro-gression of nephropathy, retinopathy, and neuropa-thy?. ### Response: 6.5 years.


Instruction: What study confirmed the findings for patients with T2D?

Output: UKPDS (United Kingdom Prospective Diabetes Study).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study confirmed the findings for patients with T2D?. ### Response: UKPDS (United Kingdom Prospective Diabetes Study)..


Instruction: What was associated with increased risk for hypoglycemia?

Output: inten-sive control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with increased risk for hypoglycemia?. ### Response: inten-sive control.


Instruction: Who recommends a target HbA1c 7% for most adult patients?

Output: American Diabetes Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who recommends a target HbA1c 7% for most adult patients?. ### Response: American Diabetes Association.


Instruction: What does the American Diabetes Association advocate for less stringent goals?

Output: 7%–8%) for patients with a limited life expectancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American Diabetes Association advocate for less stringent goals?. ### Response: 7%–8%) for patients with a limited life expectancy.


Instruction: What may be required in a reoperative setting?

Output: additional dissection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be required in a reoperative setting?. ### Response: additional dissection.


Instruction: What may tip the balance away from imposing additional risk by performing con-comitant procedures?

Output: particular risk in patients with fragile tissue integrity or general frailty, and the additional dissection that may be required in a reoperative setting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may tip the balance away from imposing additional risk by performing con-comitant procedures?. ### Response: particular risk in patients with fragile tissue integrity or general frailty, and the additional dissection that may be required in a reoperative setting.


Instruction: How are the recommendations summarized in Online Data Supplement 45.COR LOE Recommendations1 C-EO1?

Output: Management of CAD in Patients Undergoing TAVIRecommendations for Management of CAD in Patients Undergoing TAVIReferenced studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the recommendations summarized in Online Data Supplement 45.COR LOE Recommendations1 C-EO1?. ### Response: Management of CAD in Patients Undergoing TAVIRecommendations for Management of CAD in Patients Undergoing TAVIReferenced studies.


Instruction: In patients undergoing TAVI, what type of CT angiography is recommended?

Output: contrast-enhanced coronary CT angiography (in patients with a low pretest probability for CAD) or 2) an invasive coronary angiogram

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients undergoing TAVI, what type of CT angiography is recommended?. ### Response: contrast-enhanced coronary CT angiography (in patients with a low pretest probability for CAD) or 2) an invasive coronary angiogram.


Instruction: What is recommended in patients with a low pretest probability for CAD?

Output: coronary CT angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with a low pretest probability for CAD?. ### Response: coronary CT angiography.


Instruction: What is an invasive coronary angiogram recommended to assess?

Output: coronary anatomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an invasive coronary angiogram recommended to assess?. ### Response: coronary anatomy.


Instruction: What is reasonable in patients with significant AS and significant CAD?

Output: SAVR and CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in patients with significant AS and significant CAD?. ### Response: SAVR and CABG.


Instruction: What is the SYNTAX?

Output: Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the SYNTAX?. ### Response: Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery.


Instruction: What does SYNTAX stand for?

Output: Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SYNTAX stand for?. ### Response: Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery.


Instruction: What are SAVR and CABG preferred over?

Output: TAVI and PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are SAVR and CABG preferred over?. ### Response: TAVI and PCI.


Instruction: Who is most likely to have SynopsisCAD?

Output: the elderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is most likely to have SynopsisCAD?. ### Response: the elderly.


Instruction: What impacts long-term survival in a favorable way?

Output: con-comitant revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What impacts long-term survival in a favorable way?. ### Response: con-comitant revascularization.


Instruction: What is commonplace in the surgical experience?

Output: con-comitant revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is commonplace in the surgical experience?. ### Response: con-comitant revascularization.


Instruction: Why is there an argument to be made for coronary revascularization among patients un-dergoing TAVI?

Output: the effects on late outcomes are less well defined and may not be the same as for SAVR, given the different demographics and comorbid-ities of the TAVI versus SAVR populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there an argument to be made for coronary revascularization among patients un-dergoing TAVI?. ### Response: the effects on late outcomes are less well defined and may not be the same as for SAVR, given the different demographics and comorbid-ities of the TAVI versus SAVR populations.


Instruction: The effects on late outcomes are less well defined and may not be what?

Output: the same

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The effects on late outcomes are less well defined and may not be what?. ### Response: the same.


Instruction: What may not be the same as for SAVR?

Output: the effects on late outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not be the same as for SAVR?. ### Response: the effects on late outcomes.


Instruction: What are diagnostic imaging and consideration of at this point?

Output: revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are diagnostic imaging and consideration of at this point?. ### Response: revascularization.


Instruction: What is the prevalence of CAD in patients with severe AS?

Output: between 15% and 80%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of CAD in patients with severe AS?. ### Response: between 15% and 80%..


Instruction: How much does CAD vary in patients?

Output: between 15% and 80%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does CAD vary in patients?. ### Response: between 15% and 80%..


Instruction: What is CAD's impact on outcomes?

Output: controversial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CAD's impact on outcomes?. ### Response: controversial.


Instruction: When was a report downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a report downloaded?. ### Response: April 28, 2023.


Instruction: What is ezetimibe added to statin therapy after acute coronary syndromes?

Output: Grundy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ezetimibe added to statin therapy after acute coronary syndromes?. ### Response: Grundy.


Instruction: What is primary prevention S4.4-1?

Output: coronary artery calcium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is primary prevention S4.4-1?. ### Response: coronary artery calcium.