Instruction: What is the effect of intensive blood pres-sure lowering on the progression of chronic renal disease?

Output: a sys-tematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of intensive blood pres-sure lowering on the progression of chronic renal disease?. ### Response: a sys-tematic review and meta-analysis.


Instruction: What is the effect of intensive blood pressure lowering on the progression of chronic kidney disease?

Output: Effects of intensive blood pres-sure lowering on the progression of chronic kidney disease: a sys-tematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of intensive blood pressure lowering on the progression of chronic kidney disease?. ### Response: Effects of intensive blood pres-sure lowering on the progression of chronic kidney disease: a sys-tematic review and meta-analysis.


Instruction: When did CMAJ publish a sys-tematic review and meta-analysis?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did CMAJ publish a sys-tematic review and meta-analysis?. ### Response: 2013.


Instruction: What did Jafar TH, Stark PC, Schmid CH, et al. study?

Output: Progression of chronic kid-ney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Jafar TH, Stark PC, Schmid CH, et al. study?. ### Response: Progression of chronic kid-ney disease.


Instruction: What enzyme inhibits angiotensin-converting enzymes?

Output: phosphodies-terase-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What enzyme inhibits angiotensin-converting enzymes?. ### Response: phosphodies-terase-5.


Instruction: What is a patient-level meta-analysis?

Output: Progression of chronic kid-ney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a patient-level meta-analysis?. ### Response: Progression of chronic kid-ney disease.


Instruction: Ann Intern Med 2003;139:244–52.

Output: Progression of chronic kid-ney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ann Intern Med 2003;139:244–52.. ### Response: Progression of chronic kid-ney disease.


Instruction: What is NICE 2018's summary of the Chronic Heart Failure Guideline?

Output: All rights reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018's summary of the Chronic Heart Failure Guideline?. ### Response: All rights reserved.


Instruction: What is the ISBN number of the 978-1-4731-3093 -7 23 90?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ISBN number of the 978-1-4731-3093 -7 23 90?. ### Response: Chronic Heart Failure.


Instruction: What is a failure to palliative care services?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a failure to palliative care services?. ### Response: heart failure.


Instruction: What should a person with heart failure discuss with a specialist heart failure MDT?

Output: palliative care needs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a person with heart failure discuss with a specialist heart failure MDT?. ### Response: palliative care needs.


Instruction: What should people with heart failure and their families or carers have access to within the heart failure team?

Output: professionals with palliative care skills

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should people with heart failure and their families or carers have access to within the heart failure team?. ### Response: professionals with palliative care skills.


Instruction: What is commonly performed duringPCI to prevent recoil, abrupt closure, and late restenosis?

Output: Coronary stent implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is commonly performed duringPCI to prevent recoil, abrupt closure, and late restenosis?. ### Response: Coronary stent implantation.


Instruction: What is composed of either stainless steel or cobalt chro-mium alloys?

Output: 463,464BMS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is composed of either stainless steel or cobalt chro-mium alloys?. ### Response: 463,464BMS.


Instruction: Why is the risk of stent thrombosis greatest within the first 30 days after implantation?

Output: the use of DAPTis required for 30 days after implantation of BMS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the risk of stent thrombosis greatest within the first 30 days after implantation?. ### Response: the use of DAPTis required for 30 days after implantation of BMS.


Instruction: How long after implantation is the use of DAPTis required?

Output: 30 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after implantation is the use of DAPTis required?. ### Response: 30 days.


Instruction: How many types of DES are currently ap-proved in the United States?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many types of DES are currently ap-proved in the United States?. ### Response: 4.


Instruction: What are some common clinical features?

Output: sirolimus-eluting stents, paclitaxel-eluting stents, and zotarolimus-eluting stents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some common clinical features?. ### Response: sirolimus-eluting stents, paclitaxel-eluting stents, and zotarolimus-eluting stents.


Instruction: What have been shown to be associated with a reduced need for repeat revascularization and no increase in death or MI compared with BMS at 4 years’follow-up?

Output: sirolimus-eluting stents, paclitaxel-eluting stents, and zotarolimus-eluting stents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have been shown to be associated with a reduced need for repeat revascularization and no increase in death or MI compared with BMS at 4 years’follow-up?. ### Response: sirolimus-eluting stents, paclitaxel-eluting stents, and zotarolimus-eluting stents.


Instruction: What has been demon-strated in RCTs to be associated with a lower need for repeatrevascularization than paclitaxel-eluting stents?

Output: Everolimus-eluting stents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been demon-strated in RCTs to be associated with a lower need for repeatrevascularization than paclitaxel-eluting stents?. ### Response: Everolimus-eluting stents.


Instruction: How many years follow-up with no increase in death or MI compared with BMS?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years follow-up with no increase in death or MI compared with BMS?. ### Response: 4.


Instruction: How long does it take for a stent to cause death or MI?

Output: 2-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a stent to cause death or MI?. ### Response: 2-year.


Instruction: What is the reason for the longer period of risk for thrombosis compared with BMS?

Output: delayed healing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reason for the longer period of risk for thrombosis compared with BMS?. ### Response: delayed healing.


Instruction: What was the recommended minimum duration of DAPT therapy?

Output: 3 to 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the recommended minimum duration of DAPT therapy?. ### Response: 3 to 6 months.


Instruction: What is the consensus of clinical practice?

Output: 12 months of DAPT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the consensus of clinical practice?. ### Response: 12 months of DAPT.


Instruction: What are paclitaxel and sirolimus eluting stents that indicate lower risk of?

Output: late stentthrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are paclitaxel and sirolimus eluting stents that indicate lower risk of?. ### Response: late stentthrombosis.


Instruction: How long does DAPTbeyond 1 year be considered by some practitioners?

Output: reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does DAPTbeyond 1 year be considered by some practitioners?. ### Response: reasonable.


Instruction: What is more expensive than BMS?

Output: DEStherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more expensive than BMS?. ### Response: DEStherapy.


Instruction: Why is DEStherapy more expensive?

Output: avoidance of repeat procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is DEStherapy more expensive?. ### Response: avoidance of repeat procedures.


Instruction: What may bereasonable to consider use of BMS in patient subsets?

Output: the risk of restenosis is low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may bereasonable to consider use of BMS in patient subsets?. ### Response: the risk of restenosis is low.


Instruction: What is the most favorable risk-benefit profile for DES overBMS when the risk of restenosis with BMS is high?

Output: 470

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most favorable risk-benefit profile for DES overBMS when the risk of restenosis with BMS is high?. ### Response: 470.


Instruction: What has been shown that inpatients with diabetes, use of DES decreases therisk ofrestenosis compared to BMS?

Output: Pooled and meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown that inpatients with diabetes, use of DES decreases therisk ofrestenosis compared to BMS?. ### Response: Pooled and meta-analyses.


Instruction: What decreases the risk ofrestenosis compared with BMS?

Output: DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What decreases the risk ofrestenosis compared with BMS?. ### Response: DES.


Instruction: What may be moreappealing for unprotected left main PCI?

Output: DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be moreappealing for unprotected left main PCI?. ### Response: DES.


Instruction: What is the name of the disease that affects children?

Output: infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects children?. ### Response: infective endocarditis.


Instruction: What are the two diagnostic criteria for infective endocarditis?

Output: von Reyn, Duke, and modified Duke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two diagnostic criteria for infective endocarditis?. ### Response: von Reyn, Duke, and modified Duke.


Instruction: When was the Pediatr Infect Dis J.14:1079-1086?

Output: 1995

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Pediatr Infect Dis J.14:1079-1086?. ### Response: 1995.


Instruction: Infectious endocarditis in pedi-atric patients: analysis of which criteria?

Output: two diagnostic criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infectious endocarditis in pedi-atric patients: analysis of which criteria?. ### Response: two diagnostic criteria.


Instruction: What is the name of the criteria used for the diagnosis of infective endemic in children?

Output: von Reyn, Duke, and modified Duke criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the criteria used for the diagnosis of infective endemic in children?. ### Response: von Reyn, Duke, and modified Duke criteria.


Instruction: When did Pediatrics issue 112(pt 1):e467?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Pediatrics issue 112(pt 1):e467?. ### Response: 2003.


Instruction: Infectious endocarditis in pedi-atric patients: analysis of 19 cases presenting at a medical center.

Output: J Microbiol Immunol Infect. 2010;43:430–437

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infectious endocarditis in pedi-atric patients: analysis of 19 cases presenting at a medical center.. ### Response: J Microbiol Immunol Infect. 2010;43:430–437.


Instruction: What is the doi: 10.1016/S1684-1182(10)60066-7?

Output: J Microbiol Immunol Infect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1016/S1684-1182(10)60066-7?. ### Response: J Microbiol Immunol Infect.


Instruction: Syed FF, Millar BC, Prendergast BD. Molecular technology in context: a current review of what?

Output: diagnosis and management of infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Syed FF, Millar BC, Prendergast BD. Molecular technology in context: a current review of what?. ### Response: diagnosis and management of infective endocarditis.


Instruction: What is the name of the disease that causes infective endocarditis?

Output: Infectious endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes infective endocarditis?. ### Response: Infectious endocarditis.


Instruction: What was the title of the 2007 issue of Prog Cardiovasc Dis?

Output: 50:181–197

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the 2007 issue of Prog Cardiovasc Dis?. ### Response: 50:181–197.


Instruction: What is underrepresentation of renaldisease in randomized controlled trials of cardiovascular disease?

Output: Coca SG, Krumholz HM, Garg AX, et al. Underrepresentation of renaldisease in randomized controlled trials of cardiovascular disease.JAMA. 2006;296:1377–84.193

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is underrepresentation of renaldisease in randomized controlled trials of cardiovascular disease?. ### Response: Coca SG, Krumholz HM, Garg AX, et al. Underrepresentation of renaldisease in randomized controlled trials of cardiovascular disease.JAMA. 2006;296:1377–84.193.


Instruction: When did JAMA issue 296:1377–84.193?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 296:1377–84.193?. ### Response: 2006.


Instruction: What did Fox CS, Muntner P, ChenAY, et al. use of evidence-based therapies in short-term outcomes of?

Output: ST-segment elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Fox CS, Muntner P, ChenAY, et al. use of evidence-based therapies in short-term outcomes of?. ### Response: ST-segment elevation myocardial infarction.


Instruction: What is elevation myocardial infarction in patients with chronic kidney disease?

Output: non-ST-segment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is elevation myocardial infarction in patients with chronic kidney disease?. ### Response: non-ST-segment.


Instruction: What is a report from the National Cardiovascular Data AcuteCoronary Treatment and Intervention Outcomes Network registry?

Output: Use of evidence-based therapies inshort-term outcomes of ST-segment elevation myocardial infarction andnon-ST-segment elevation myocardial infarction in patients with chronickidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report from the National Cardiovascular Data AcuteCoronary Treatment and Intervention Outcomes Network registry?. ### Response: Use of evidence-based therapies inshort-term outcomes of ST-segment elevation myocardial infarction andnon-ST-segment elevation myocardial infarction in patients with chronickidney disease.


Instruction: When did Circulation. 2010;121:357–65.194.

Output: Cir-culation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2010;121:357–65.194.. ### Response: Cir-culation.


Instruction: Where is Get With the Guidelines available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Get With the Guidelines available?. ### Response: http://www.americanheart.org/GWTG.


Instruction: What is the primary versus tenecteplase-facilitatedpercutaneous coronary intervention in patients with ST-segment ele-vation acute myocardial infarction?

Output: ASSENT-4 PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary versus tenecteplase-facilitatedpercutaneous coronary intervention in patients with ST-segment ele-vation acute myocardial infarction?. ### Response: ASSENT-4 PCI.


Instruction: What was the outcome of the randomised trial?

Output: Primary versus tenecteplase-facilitatedpercutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the randomised trial?. ### Response: Primary versus tenecteplase-facilitatedpercutaneous coronary intervention.


Instruction: What is the acronym for Cardiology/American Heart Association TaskForce on Performance Measures?

Output: American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Cardiology/American Heart Association TaskForce on Performance Measures?. ### Response: American College of Cardiology.


Instruction: What is a regional system to providetime access to percutaneous coronary intervention for ST-elevationmyocardial infarction?

Output: citywide protocol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a regional system to providetime access to percutaneous coronary intervention for ST-elevationmyocardial infarction?. ### Response: citywide protocol.


Instruction: What is the name of the group that developed performance measures for adults with ST-elevationmyocardial infarction?

Output: American College ofCardiology/American Heart Association Task Force on PerformanceMeasures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that developed performance measures for adults with ST-elevationmyocardial infarction?. ### Response: American College ofCardiology/American Heart Association Task Force on PerformanceMeasures.


Instruction: What is the acronym for Heart Association Task Force on PerformanceMeasures?

Output: Writing Committee to Develop Performance Measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Heart Association Task Force on PerformanceMeasures?. ### Response: Writing Committee to Develop Performance Measures.


Instruction: When was Circulation 118:2596-648.200?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation 118:2596-648.200?. ### Response: 2008.


Instruction: What is a citywide protocol for?

Output: primaryPCI in ST-segment elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a citywide protocol for?. ### Response: primaryPCI in ST-segment elevation myocardial infarction.


Instruction: Where is the National Cardiovascular Data Registry located?

Output: http://www.ncdr.com. 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the National Cardiovascular Data Registry located?. ### Response: http://www.ncdr.com. 2009.


Instruction: What is the acronym for Inpatient Hospital Quality Measures?

Output: Measure Comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Inpatient Hospital Quality Measures?. ### Response: Measure Comparison.


Instruction: Where is the Acute Myocardial Infarction Core Measure Set located?

Output: The Joint Commission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Acute Myocardial Infarction Core Measure Set located?. ### Response: The Joint Commission.


Instruction: How many years ago was the Med.2008:358:231–40.201 available?

Output: –648.200

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years ago was the Med.2008:358:231–40.201 available?. ### Response: –648.200.


Output: /H11001Infarction /H11001Core/H11001Measure /H11001Set.htm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: http://www.jointcommission.org/PerformanceMeasurement/Acute/H11001Myocardial?. ### Response: /H11001Infarction /H11001Core/H11001Measure /H11001Set.htm.


Instruction: What is the name of the measure set?

Output: The Joint Commission. Acute Myocardial Infarction Core Measure Set

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the measure set?. ### Response: The Joint Commission. Acute Myocardial Infarction Core Measure Set.


Instruction: When was the Core Measure Set accessed?

Output: June 10, 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Core Measure Set accessed?. ### Response: June 10, 2009.


Instruction: What is the MIC of relative penicillin-resistant strains?

Output: >0.12–<0.5 µ g/mL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MIC of relative penicillin-resistant strains?. ### Response: >0.12–<0.5 µ g/mL.


Instruction: How long is it reasonable to administer penicillin to patients with VGS or S gallolyticus (bovis) IE?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it reasonable to administer penicillin to patients with VGS or S gallolyticus (bovis) IE?. ### Response: 4 weeks.


Instruction: What is a reasonable alternative to penicillin if shortages of penicillin exist?

Output: Ampicillin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable alternative to penicillin if shortages of penicillin exist?. ### Response: Ampicillin.


Instruction: If the isolate is ceftriaxone susceptible, what may be considered?

Output: ceftriaxone alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the isolate is ceftriaxone susceptible, what may be considered?. ### Response: ceftriaxone alone.


Instruction: What is considered a reasonable alternative if the patient is intolerant of -lactam therapy?

Output: Vancomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered a reasonable alternative if the patient is intolerant of -lactam therapy?. ### Response: Vancomycin.


Instruction: What is recommended in both scenarios?

Output: Consultation with an infectious diseases special-ist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in both scenarios?. ### Response: Consultation with an infectious diseases special-ist.


Instruction: How long is it reasonable to administer penicillin with gentamicin for the first 2 weeks of therapy?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it reasonable to administer penicillin with gentamicin for the first 2 weeks of therapy?. ### Response: 4 weeks.


Instruction: What is the class IIa; Level of Evidence C?

Output: Vancomycin alone may be a reasonable alternative in patients who are intolerant of β-lactam therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class IIa; Level of Evidence C?. ### Response: Vancomycin alone may be a reasonable alternative in patients who are intolerant of β-lactam therapy.


Instruction: What is a reasonable alternative in patients who are intolerant of -lactam therapy?

Output: Vancomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable alternative in patients who are intolerant of -lactam therapy?. ### Response: Vancomycin.


Instruction: What is the Penicillin MIC 0.5 g/mL?

Output: <0.5 µ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Penicillin MIC 0.5 g/mL?. ### Response: <0.5 µ.


Instruction: What are A defec-tiva and Granulicatella species formerly known as?

Output: nutri-tionally variant streptococci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are A defec-tiva and Granulicatella species formerly known as?. ### Response: nutri-tionally variant streptococci.


Instruction: What is rare and difficult to cure microbiologically compared with IE caused by these microorganisms?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rare and difficult to cure microbiologically compared with IE caused by these microorganisms?. ### Response: IE.


Instruction: What is more difficult to cure microbiologically compared with IE caused by a strain of non-nutritionally variant VGS?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more difficult to cure microbiologically compared with IE caused by a strain of non-nutritionally variant VGS?. ### Response: IE.


Instruction: What is reasonable to administer a combination regimen that includes ampicillin (12 g/d in divided doses) or penicillin?

Output: in patients with IE caused by A defectiva and Granulicatella species

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to administer a combination regimen that includes ampicillin (12 g/d in divided doses) or penicillin?. ### Response: in patients with IE caused by A defectiva and Granulicatella species.


Instruction: What is gen-tamicin?

Output: 3 mg·kg−1·d−1 in 2–3 divided doses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is gen-tamicin?. ### Response: 3 mg·kg−1·d−1 in 2–3 divided doses.


Instruction: What animal model shows that vancomycin is effective?

Output: experimental endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What animal model shows that vancomycin is effective?. ### Response: experimental endocarditis.


Instruction: What animal model of experimental endocarditis suggests that the addition of gentamicin is not needed?

Output: animal model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What animal model of experimental endocarditis suggests that the addition of gentamicin is not needed?. ### Response: animal model.


Instruction: What is a reasonable alternative treatment option for VGS isolates that are susceptible to ceftriaxone?

Output: Ceftriaxone combined with gentamicin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable alternative treatment option for VGS isolates that are susceptible to ceftriaxone?. ### Response: Ceftriaxone combined with gentamicin.


Instruction: What is the MIC of VGS isolates that are susceptible to ceftriaxone on the basis of the Clinical and Laboratory Standards Institute definition?

Output: ≥0.5 µg/mL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MIC of VGS isolates that are susceptible to ceftriaxone on the basis of the Clinical and Laboratory Standards Institute definition?. ### Response: ≥0.5 µg/mL.


Instruction: What is a resistance to penicillin?

Output: VGS isolates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a resistance to penicillin?. ### Response: VGS isolates.


Instruction: There is no reported clinical experience with the combination of ampicillin plus what?

Output: ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no reported clinical experience with the combination of ampicillin plus what?. ### Response: ceftriaxone.


Instruction: What is the combination of ampicillin plus ceftriaxone for?

Output: IE caused by these organisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the combination of ampicillin plus ceftriaxone for?. ### Response: IE caused by these organisms.


Instruction: What is IE caused by?

Output: relatively resistant strains

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is IE caused by?. ### Response: relatively resistant strains.


Instruction: How is therapy of NVE caused by Highly Penicillin-Susceptible VGS?

Output: Table 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is therapy of NVE caused by Highly Penicillin-Susceptible VGS?. ### Response: Table 7.


Instruction: Where can you find NICE guidance on r elated topics?

Output: NICE webpage on acut e cor onar y syndr omes .

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find NICE guidance on r elated topics?. ### Response: NICE webpage on acut e cor onar y syndr omes ..


Instruction: What is t he NICE webpage on?

Output: acut e cor onar y syndr omes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he NICE webpage on?. ### Response: acut e cor onar y syndr omes.


Instruction: How was the guideline developed?

Output: de veloped

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the guideline developed?. ### Response: de veloped.


Instruction: NICE has pr oduced tools and what else?

Output: r esour ces t o help y ou put t his guideline int o practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: NICE has pr oduced tools and what else?. ### Response: r esour ces t o help y ou put t his guideline int o practice.


Instruction: What has pr oduced tools and r esour ces t o help y ou put his guideline int he practice?

Output: NICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has pr oduced tools and r esour ces t o help y ou put his guideline int he practice?. ### Response: NICE.


Instruction: For general help and advice on putting NICE guidance int the practice, see what?

Output: resour

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For general help and advice on putting NICE guidance int the practice, see what?. ### Response: resour.


Instruction: What is CG126?

Output: Stable angina: management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CG126?. ### Response: Stable angina: management.


Instruction: What is NICE 2022?

Output: Stable angina: management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2022?. ### Response: Stable angina: management.


Instruction: When was the last updat?

Output: 25 August 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat?. ### Response: 25 August 2016.


Instruction: What was associated with an increased risk of death orhospitalization for ACS?

Output: clopidogrel and PPI therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with an increased risk of death orhospitalization for ACS?. ### Response: clopidogrel and PPI therapy.


Instruction: How many patients were discharged forACS at any time during follow-up?

Output: 8205

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were discharged forACS at any time during follow-up?. ### Response: 8205.


Instruction: What did the VA's medical records and pharmacy database show?

Output: concomitant clopidogrel and PPI therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the VA's medical records and pharmacy database show?. ### Response: concomitant clopidogrel and PPI therapy.


Instruction: What did a retrospective data analysis from the National Heart,Lung, and Blood Institute Dynamic Registry show?

Output: have not found an effect of PPItherapy on the clinical effect of clopidogrel in ACS patients,post-ACS patients, and a general post-PCI population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a retrospective data analysis from the National Heart,Lung, and Blood Institute Dynamic Registry show?. ### Response: have not found an effect of PPItherapy on the clinical effect of clopidogrel in ACS patients,post-ACS patients, and a general post-PCI population.


Instruction: What was assessed as a class in combination with a clopidogreland an aspirin regimen?

Output: PPI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was assessed as a class in combination with a clopidogreland an aspirin regimen?. ### Response: PPI.


Instruction: What does clopidogrel have on ACS patients?

Output: increased risk of death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does clopidogrel have on ACS patients?. ### Response: increased risk of death.


Instruction: What is the name of a PPI that inhibits CYP450 2C19?

Output: omeprazole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a PPI that inhibits CYP450 2C19?. ### Response: omeprazole.


Instruction: In addition to omeprazole and lansopra-zole, what is another PPI?

Output: rabeprazole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to omeprazole and lansopra-zole, what is another PPI?. ### Response: rabeprazole.


Instruction: What has been reported to significantly decrease the inhibitory effect of clopidogrel on platelet aggregation?

Output: PPI treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been reported to significantly decrease the inhibitory effect of clopidogrel on platelet aggregation?. ### Response: PPI treatment.


Instruction: What did one study report that the PPI pantoprazole was not associated with?

Output: recurrentMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did one study report that the PPI pantoprazole was not associated with?. ### Response: recurrentMI.


Instruction: What is topantoprazole’s lack of inhibition of?

Output: CYP450 2C19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is topantoprazole’s lack of inhibition of?. ### Response: CYP450 2C19.


Instruction: Other studies have examined the P2Y12receptor inhibitorprescribed with what drug?

Output: PPI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Other studies have examined the P2Y12receptor inhibitorprescribed with what drug?. ### Response: PPI.


Instruction: What open-label drug study evaluated the effects of the PPI lansoprazole on thepharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects?

Output: One

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What open-label drug study evaluated the effects of the PPI lansoprazole on thepharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects?. ### Response: One.


Instruction: What was reduced in patients who took clopidogrel and lansoprazole?

Output: inhibition of plateletaggregation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reduced in patients who took clopidogrel and lansoprazole?. ### Response: inhibition of plateletaggregation.


Instruction: What was unaffected after a prasugrel dose?

Output: platelet aggre-gation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was unaffected after a prasugrel dose?. ### Response: platelet aggre-gation.


Instruction: What did another study assess the association of PPIs with thepharmacodynamics and clinical efficacy of clopidogrel andprasugrel?

Output: COGENT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did another study assess the association of PPIs with thepharmacodynamics and clinical efficacy of clopidogrel andprasugrel?. ### Response: COGENT.


Instruction: How many randomized trials did thePRINCIPLE trial compare PPI to?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized trials did thePRINCIPLE trial compare PPI to?. ### Response: 2.


Instruction: What did the TRITON–TIMI 38 trial show?

Output: first, PPI treatment attenuated the pharmacody-namic effects of clopidogrel and, to a lesser extent, those ofprasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the TRITON–TIMI 38 trial show?. ### Response: first, PPI treatment attenuated the pharmacody-namic effects of clopidogrel and, to a lesser extent, those ofprasugrel.


Instruction: What did PPI treatment attenuate the pharmacodynamic effects of clopidogrel and to a lesser extent prasugrel?

Output: inhibition of plateletaggregation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did PPI treatment attenuate the pharmacodynamic effects of clopidogrel and to a lesser extent prasugrel?. ### Response: inhibition of plateletaggregation.


Instruction: What did not affect the clinicaloutcome of patients given clopidogrl or praspigrel.

Output: PPI treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not affect the clinicaloutcome of patients given clopidogrl or praspigrel.. ### Response: PPI treatment.


Instruction: What was true for all PPIs studied?

Output: PPI treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was true for all PPIs studied?. ### Response: PPI treatment.


Instruction: What may be confounded by selection bias?

Output: Observational trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be confounded by selection bias?. ### Response: Observational trials.


Instruction: What was compared with omeprazole in COGENT?

Output: clopi-dogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was compared with omeprazole in COGENT?. ### Response: clopi-dogrel.


Instruction: How many patients started dual antiplatelet therapy with aspirin and clopidogrel?

Output: 3627

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients started dual antiplatelet therapy with aspirin and clopidogrel?. ### Response: 3627.


Instruction: What was the primary cardiovascular endpoint between clopi-dogrel plus omeprazole and clopidogrel plus placebo?

Output: HR:1.02

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary cardiovascular endpoint between clopi-dogrel plus omeprazole and clopidogrel plus placebo?. ### Response: HR:1.02.


Instruction: What is the name of the book that describes the treatment of chronic heart failure?

Output: 223 7.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes the treatment of chronic heart failure?. ### Response: 223 7.1.


Instruction: What type of rehabilitation can be used?

Output: Home -based versus centre -based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of rehabilitation can be used?. ### Response: Home -based versus centre -based.


Instruction: What is the difference between home based and centre based rehabilitation for people with heart failure?

Output: clinical and cost effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between home based and centre based rehabilitation for people with heart failure?. ### Response: clinical and cost effectiveness.


Instruction: What is heart failure?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heart failure?. ### Response: HF.


Instruction: What is economic evidence?

Output: Evidence statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is economic evidence?. ### Response: Evidence statements.


Instruction: What type of monitoring is used for management of chronic heart failure?

Output: biomarker -based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of monitoring is used for management of chronic heart failure?. ### Response: biomarker -based.


Instruction: What is 233 8.1.1 Introduction?

Output: Monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 233 8.1.1 Introduction?. ### Response: Monitoring.


Instruction: What is the clinical and cost effectiveness of biomarker based monitoring?

Output: 238 8.1.2  Review question: What is the clinical and cost effectiveness of biomarker -based monitoring, monitoring with cardiac MRI, and m onitoring with repeated echocardiography in people with heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical and cost effectiveness of biomarker based monitoring?. ### Response: 238 8.1.2  Review question: What is the clinical and cost effectiveness of biomarker -based monitoring, monitoring with cardiac MRI, and m onitoring with repeated echocardiography in people with heart failure.


Instruction: What is monitoring with cardiac MRI and repeated echocardiography in people with heart failure?

Output: biomarker -based monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is monitoring with cardiac MRI and repeated echocardiography in people with heart failure?. ### Response: biomarker -based monitoring.


Instruction: In people with heart failure?

Output: clinical and cost effectiveness of home -based versus centre -based rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In people with heart failure?. ### Response: clinical and cost effectiveness of home -based versus centre -based rehabilitation.


Instruction: What is used to monitor for management of chronic pain?

Output: repeated biomarker measurement or imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to monitor for management of chronic pain?. ### Response: repeated biomarker measurement or imaging.


Instruction: How does economic evidence compare to clinical evidence?

Output: 252

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does economic evidence compare to clinical evidence?. ### Response: 252.


Instruction: What is used for management of chronic heart failure in people who also have chronic kidney disease?

Output: repeated biomarker measurement or imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used for management of chronic heart failure in people who also have chronic kidney disease?. ### Response: repeated biomarker measurement or imaging.


Instruction: What is monitoring with cardiac MRI?

Output: biomarker -based monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is monitoring with cardiac MRI?. ### Response: biomarker -based monitoring.


Instruction: What is CVD?

Output: cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CVD?. ### Response: cardiovascular disease.


Instruction: What is MI?

Output: myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MI?. ### Response: myocardial infarction.


Instruction: Where can you find the latest version of the RCT?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the latest version of the RCT?. ### Response: http://ahajournals.org.


Instruction: When will the version be available?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the version be available?. ### Response: May 1, 2023.


Instruction: What is a metabolic syndrome?

Output: abdominal obesity, hy -pertension, diabetes, and dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a metabolic syndrome?. ### Response: abdominal obesity, hy -pertension, diabetes, and dyslipidemia.


Instruction: What are some metabolic syndromes?

Output: abdominal obesity, hy -pertension, diabetes, and dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some metabolic syndromes?. ### Response: abdominal obesity, hy -pertension, diabetes, and dyslipidemia.


Instruction: How did SPRINT define patients with increased cardiovascular risk?

Output: thosemeeting at least 1 of the following criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did SPRINT define patients with increased cardiovascular risk?. ### Response: thosemeeting at least 1 of the following criteria.


Instruction: What is another type of cardiovascular disease?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another type of cardiovascular disease?. ### Response: stroke.


Instruction: What is the risk for cardiovascular disease based on the Framingham riskscore?

Output: reduction in the primary composite outcomeof nonfatal myocardial infarction, nonfatal stroke, or death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk for cardiovascular disease based on the Framingham riskscore?. ### Response: reduction in the primary composite outcomeof nonfatal myocardial infarction, nonfatal stroke, or death.


Instruction: How old is this trial?

Output: 60 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is this trial?. ### Response: 60 years.


Instruction: How old is the risk score?

Output: 75 years or older

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is the risk score?. ### Response: 75 years or older.


Instruction: What was the baseline SBP of adults with diabetes or prior stroke?

Output: less than140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the baseline SBP of adults with diabetes or prior stroke?. ### Response: less than140 mm Hg.


Instruction: How did the trial find that targetingSBP to less than 120 mm Hg significantly reduced fatal and nonfatal strokes?

Output: there were more serious adverse events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the trial find that targetingSBP to less than 120 mm Hg significantly reduced fatal and nonfatal strokes?. ### Response: there were more serious adverse events.


Instruction: What was the RR of ACCORD?

Output: 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of ACCORD?. ### Response: 40.


Instruction: What was RR, CI, 0.80 to?

Output: 1.11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was RR, CI, 0.80 to?. ### Response: 1.11.


Instruction: What is the RR of stroke?

Output: 0.58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the RR of stroke?. ### Response: 0.58.


Instruction: What was the CI of stroke to death from cardiovascular events?

Output: 0.80 to 1.11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the CI of stroke to death from cardiovascular events?. ### Response: 0.80 to 1.11.


Instruction: The study found a reduction in what?

Output: stroke events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The study found a reduction in what?. ### Response: stroke events.


Instruction: What should be added to the end of the sentence under the heading "High Value Care" on page 435?

Output: insome patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be added to the end of the sentence under the heading "High Value Care" on page 435?. ### Response: insome patients.


Instruction: What is most benefit achieved by aimingfor lower BP targets?

Output: acceptableharms and costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is most benefit achieved by aimingfor lower BP targets?. ### Response: acceptableharms and costs.


Instruction: What does the pharmacologic treatment of patients with an SBP of 150 mm Hg or greater have?

Output: acceptableharms and costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the pharmacologic treatment of patients with an SBP of 150 mm Hg or greater have?. ### Response: acceptableharms and costs.


Instruction: What is the name of the committee responsible for the clinical guidelines of the American College of Physicians and the Commissionon Health of the Public and Science?

Output: ClinicalGuide-lines Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee responsible for the clinical guidelines of the American College of Physicians and the Commissionon Health of the Public and Science?. ### Response: ClinicalGuide-lines Committee.


Instruction: What is a clinical practice guideline from the American College of Physicians and the American Academy ofFamily Physicians?

Output: Pharmacologic treatment of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a clinical practice guideline from the American College of Physicians and the American Academy ofFamily Physicians?. ### Response: Pharmacologic treatment of hypertension.


Instruction: How old are adults with hypertension?

Output: 60 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are adults with hypertension?. ### Response: 60 years.


Instruction: What year did Ann Intern Med publish?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Intern Med publish?. ### Response: 2017.


Instruction: What is the name of the systematic review and meta-analysis of benefits and harms of intensive blood pressure treatment in adults aged 60 years or older?

Output: beneﬁts andharms of intensive blood pressure treatment in adults aged 60 years or older:a systematic review and meta-analysis. Ann Intern Med. 2017;166:419-429

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis of benefits and harms of intensive blood pressure treatment in adults aged 60 years or older?. ### Response: beneﬁts andharms of intensive blood pressure treatment in adults aged 60 years or older:a systematic review and meta-analysis. Ann Intern Med. 2017;166:419-429.


Instruction: What year did Ann Intern Med issue 166:419-429?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Intern Med issue 166:419-429?. ### Response: 2017.


Instruction: When was Annals of Internal Medicine Vol. 166 No. 6 published?

Output: 21 March 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Annals of Internal Medicine Vol. 166 No. 6 published?. ### Response: 21 March 2017.


Instruction: Who was the author of the book?

Output: Sarath Ss

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of the book?. ### Response: Sarath Ss.


Instruction: When did Sarath Ss upload the book to her website?

Output: 05/03/2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Sarath Ss upload the book to her website?. ### Response: 05/03/2023.


Instruction: What is the 2017 VA/SCD GuidelineCirculation?

Output: 2018;138:e272–e391

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 VA/SCD GuidelineCirculation?. ### Response: 2018;138:e272–e391.


Instruction: What is a systematic review and meta-analysis of implantable cardioverter-defibrillators?

Output: Implantable cardioverter-defibrillators in adults with congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis of implantable cardioverter-defibrillators?. ### Response: Implantable cardioverter-defibrillators in adults with congenital heart disease.


Instruction: What is the name of the multi-centre study of implantable cardioverter defibrillators in adults with congenital heart disease?

Output: Outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-centre study of implantable cardioverter defibrillators in adults with congenital heart disease?. ### Response: Outcome.


Instruction: When did Eur Heart J. 2007:28:1854-61?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 2007:28:1854-61?. ### Response: 2007.


Instruction: What is one of the most common arrhythmias in postoperative tetralogy of Fallot?

Output: Ventricular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the most common arrhythmias in postoperative tetralogy of Fallot?. ### Response: Ventricular.


Instruction: What is ventricular arrhythmia in postoperative tetralogy of Fallot?

Output: Left-sided ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ventricular arrhythmia in postoperative tetralogy of Fallot?. ### Response: Left-sided ablation.


Instruction: What is the value of programmed ventricular stimulation?

Output: S10.8-20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of programmed ventricular stimulation?. ### Response: S10.8-20.


Instruction: When was a multicenter study conducted?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a multicenter study conducted?. ### Response: 2004.


Instruction: What are implantable cardioverter-defibrillators in tetralogy of Fallot?

Output: Ventricular arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implantable cardioverter-defibrillators in tetralogy of Fallot?. ### Response: Ventricular arrhythmias.


Instruction: What is re-entry using anatomi-cally determined isthmuses: a curable ventricular tachycardia?

Output: repaired congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is re-entry using anatomi-cally determined isthmuses: a curable ventricular tachycardia?. ### Response: repaired congenital heart disease.


Instruction: What is the sub-strate of anatomi-cal isthmuses identified by electroanatomical mapping?

Output: ventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sub-strate of anatomi-cal isthmuses identified by electroanatomical mapping?. ### Response: ventricular tachycardia.


Instruction: What is left-sided ablation of ventricular tachycardia in adults with repaired tetralogy of Fallot?

Output: a case series

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is left-sided ablation of ventricular tachycardia in adults with repaired tetralogy of Fallot?. ### Response: a case series.


Instruction: What is the sub-strate for ventricular tachycardia in repaired tetralogy of Fallot?

Output: Arrhythmogenic anatomi-cal isthmuses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sub-strate for ventricular tachycardia in repaired tetralogy of Fallot?. ### Response: Arrhythmogenic anatomi-cal isthmuses.


Instruction: What are arrhythmogenic anatomi-cal isthmuses identified by electroanatomical mapping?

Output: the sub-strate for ventricular tachycardia in repaired tetralogy of Fallot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are arrhythmogenic anatomi-cal isthmuses identified by electroanatomical mapping?. ### Response: the sub-strate for ventricular tachycardia in repaired tetralogy of Fallot.


Instruction: What is tachycardia in adults with repaired congenital heart disease?

Output: ventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tachycardia in adults with repaired congenital heart disease?. ### Response: ventricular tachycardia.


Instruction: What is the critical right ventricular isthmus?

Output: Catheter ablation of ventricular tachycardia after repair of congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the critical right ventricular isthmus?. ### Response: Catheter ablation of ventricular tachycardia after repair of congenital heart disease.


Instruction: What is the cause of death in adults with congenital heart disease?

Output: German National Register for Congenital Heart Defects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of death in adults with congenital heart disease?. ### Response: German National Register for Congenital Heart Defects.


Instruction: What is a multicenter study?

Output: Value of programmed ventricular stimulation after tetralogy of fallot repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a multicenter study?. ### Response: Value of programmed ventricular stimulation after tetralogy of fallot repair.


Instruction: What is an analysis of the German National Register for Congenital Heart Defects?

Output: Cause of death in adults with congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an analysis of the German National Register for Congenital Heart Defects?. ### Response: Cause of death in adults with congenital heart disease.


Instruction: Int J Cardiol. 2016;211:31–6.

Output: congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol. 2016;211:31–6.. ### Response: congenital heart disease.


Instruction: How are congenital heart defects repaired before adult life?

Output: Incidence and predictors of sudden cardiac arrest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are congenital heart defects repaired before adult life?. ### Response: Incidence and predictors of sudden cardiac arrest.


Instruction: What is the name of the journal that deals with heart defects beyond the age of 60?

Output: Int J Cardiol. 2016;211:31–6. S10.8-28. Gallego P , Gonzalez AE, Sanchez-Recalde A, et al. Incidence and predictors of sudden cardiac arrest in adults with congenital heart defects repaired before adult life. Am J Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that deals with heart defects beyond the age of 60?. ### Response: Int J Cardiol. 2016;211:31–6. S10.8-28. Gallego P , Gonzalez AE, Sanchez-Recalde A, et al. Incidence and predictors of sudden cardiac arrest in adults with congenital heart defects repaired before adult life. Am J Cardiol.


Instruction: Who is the author of this study?

Output: Al-Khatib

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of this study?. ### Response: Al-Khatib.


Instruction: What is the name of the section that highlights some impor tant changes t hat ma y result fr om implementing t his guideline identified at publication in July 2014?

Output: g etting star ted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the section that highlights some impor tant changes t hat ma y result fr om implementing t his guideline identified at publication in July 2014?. ### Response: g etting star ted.


Instruction: How many inputs did stakeholders, e xper ts and healt h professionals receive?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many inputs did stakeholders, e xper ts and healt h professionals receive?. ### Response: 3.


Instruction: How many areas have been identified that could have a big impact on practice or could be challenging to implement?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many areas have been identified that could have a big impact on practice or could be challenging to implement?. ### Response: 3.


Instruction: What would be needed to fully implement t he guideline?

Output: other changes t o practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be needed to fully implement t he guideline?. ### Response: other changes t o practice.


Instruction: What is a non-HDL cholester ol?

Output: Non-high-density lipopr otein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a non-HDL cholester ol?. ### Response: Non-high-density lipopr otein.


Instruction: What is another term for non-high-density lipopr otein?

Output: LDL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for non-high-density lipopr otein?. ### Response: LDL.


Instruction: Is it necessary to fully implement the guideline?

Output: Ho wever, other changes t o practice ma y be needed t o fully implement t he guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is it necessary to fully implement the guideline?. ### Response: Ho wever, other changes t o practice ma y be needed t o fully implement t he guideline.


Instruction: Non-HDL cholest erol is seen to be a bett er car diovascular disease (CVD) risk indicator than what?

Output: lo w-density lipopr otein

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Non-HDL cholest erol is seen to be a bett er car diovascular disease (CVD) risk indicator than what?. ### Response: lo w-density lipopr otein.


Instruction: What is the mor e accurat e, practical and cost eff ective of Non-high-density lipopr otein?

Output: cholest erol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mor e accurat e, practical and cost eff ective of Non-high-density lipopr otein?. ### Response: cholest erol.


Instruction: What is not needed for a f asting blood sample?

Output: A f asting blood sample is not needed. This is more con venient f or patient s and ma y reduce t he need f or additional blood samples

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not needed for a f asting blood sample?. ### Response: A f asting blood sample is not needed. This is more con venient f or patient s and ma y reduce t he need f or additional blood samples.


Instruction: What is more convenient f or patient s and reduce t he need for additional blood samples?

Output: A f asting blood sample

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more convenient f or patient s and reduce t he need for additional blood samples?. ### Response: A f asting blood sample.


Instruction: Who is equesting lipids?

Output: GPs, practice nurses and community pharmacist s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is equesting lipids?. ### Response: GPs, practice nurses and community pharmacist s.


Instruction: What do GPs, practice nurses and community pharmacists need to do?

Output: change t heir practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do GPs, practice nurses and community pharmacists need to do?. ### Response: change t heir practice.


Instruction: What do Laborat ories also need to change?

Output: t heir r epor ting pr ocedur es

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do Laborat ories also need to change?. ### Response: t heir r epor ting pr ocedur es.


Instruction: What percentage of laborat ories included non-HDL cholest erol in their repor ts?

Output: 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of laborat ories included non-HDL cholest erol in their repor ts?. ### Response: 10%.


Instruction: What is the UKNEQ AS?

Output: The Unit ed K ingdom National Ext ernal Quality Assessment Ser vice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the UKNEQ AS?. ### Response: The Unit ed K ingdom National Ext ernal Quality Assessment Ser vice.


Instruction: Why was there a lack of demand for healt hcare workers?

Output: Healt hcare workers ma y need educating

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there a lack of demand for healt hcare workers?. ### Response: Healt hcare workers ma y need educating.


Instruction: What does the non-HDL cholest erol test mean?

Output: It is mor e accurat e, mor e practical and cost eff ect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the non-HDL cholest erol test mean?. ### Response: It is mor e accurat e, mor e practical and cost eff ect.


Instruction: How do workers interpret the laborat ory results?

Output: ma y need t o change t heir practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do workers interpret the laborat ory results?. ### Response: ma y need t o change t heir practice.


Instruction: What is a risk assessment and r eduction, including lipid modification?

Output: Cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk assessment and r eduction, including lipid modification?. ### Response: Cardiovascular disease.


Instruction: What is the last updat ed 10 F ebruar?

Output: 2023Page 26of 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 10 F ebruar?. ### Response: 2023Page 26of 40.


Instruction: What is the last updat ed 10 F ebruar y 2023Page 26of 40?

Output: Notice of right s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 10 F ebruar y 2023Page 26of 40?. ### Response: Notice of right s.


Instruction: What is the name of the disease that affects children?

Output: infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects children?. ### Response: infective endocarditis.


Instruction: What are the two diagnostic criteria for infective endocarditis?

Output: von Reyn, Duke, and modified Duke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two diagnostic criteria for infective endocarditis?. ### Response: von Reyn, Duke, and modified Duke.


Instruction: When was the Pediatr Infect Dis J.14:1079-1086?

Output: 1995

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Pediatr Infect Dis J.14:1079-1086?. ### Response: 1995.


Instruction: Infectious endocarditis in pedi-atric patients: analysis of which criteria?

Output: two diagnostic criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infectious endocarditis in pedi-atric patients: analysis of which criteria?. ### Response: two diagnostic criteria.


Instruction: What is the name of the criteria used for the diagnosis of infective endemic in children?

Output: von Reyn, Duke, and modified Duke criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the criteria used for the diagnosis of infective endemic in children?. ### Response: von Reyn, Duke, and modified Duke criteria.


Instruction: When did Pediatrics issue 112(pt 1):e467?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Pediatrics issue 112(pt 1):e467?. ### Response: 2003.


Instruction: Infectious endocarditis in pedi-atric patients: analysis of 19 cases presenting at a medical center.

Output: J Microbiol Immunol Infect. 2010;43:430–437

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infectious endocarditis in pedi-atric patients: analysis of 19 cases presenting at a medical center.. ### Response: J Microbiol Immunol Infect. 2010;43:430–437.


Instruction: What is the doi: 10.1016/S1684-1182(10)60066-7?

Output: J Microbiol Immunol Infect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1016/S1684-1182(10)60066-7?. ### Response: J Microbiol Immunol Infect.


Instruction: Syed FF, Millar BC, Prendergast BD. Molecular technology in context: a current review of what?

Output: diagnosis and management of infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Syed FF, Millar BC, Prendergast BD. Molecular technology in context: a current review of what?. ### Response: diagnosis and management of infective endocarditis.


Instruction: What is the name of the disease that causes infective endocarditis?

Output: Infectious endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes infective endocarditis?. ### Response: Infectious endocarditis.


Instruction: What was the title of the 2007 issue of Prog Cardiovasc Dis?

Output: 50:181–197

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the 2007 issue of Prog Cardiovasc Dis?. ### Response: 50:181–197.


Instruction: What is the name of the convertase subtilisin/kexin type 9 inhibitor?

Output: PCSK9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the convertase subtilisin/kexin type 9 inhibitor?. ### Response: PCSK9.


Instruction: What is Section 10.3 of the 2008 ACCF/AHA/HRS Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities?

Output: discharge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Section 10.3 of the 2008 ACCF/AHA/HRS Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities?. ### Response: discharge.


Instruction: What are AF, atrial flutter, and other supraventricular tachyarrhythmias triggered by?

Output: excessive sympathetic stimulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are AF, atrial flutter, and other supraventricular tachyarrhythmias triggered by?. ### Response: excessive sympathetic stimulation.


Instruction: What is the cause of the stretch due to LV?

Output: excessive sympathetic stimulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of the stretch due to LV?. ### Response: excessive sympathetic stimulation.


Instruction: When will the ahajournals.org be available?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the ahajournals.org be available?. ### Response: April 28, 2023.


Instruction: Who is a Content Reviewer at the Cleveland Clinic Foundation?

Output: Patrick L. Whitlow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Content Reviewer at the Cleveland Clinic Foundation?. ### Response: Patrick L. Whitlow.


Instruction: What is the name of the Harvard Medical School professor of medicine?

Output: David O. Williams

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Harvard Medical School professor of medicine?. ### Response: David O. Williams.


Instruction: Who is the head of the ACC/AHA Task Force onPractice Guidelines?

Output: Clyde W. Yancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the head of the ACC/AHA Task Force onPractice Guidelines?. ### Response: Clyde W. Yancy.


Instruction: What is the name of the ACC/AHA Task Force onPractice Guidelines?

Output: Clyde W. Yancy Content Reviewer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACC/AHA Task Force onPractice Guidelines?. ### Response: Clyde W. Yancy Content Reviewer.


Instruction: Who is the Vice Dean for Diversity andInclusion, Chief of Medicine-Cardiology, and Professor?

Output: Clyde W. Yancy Content Reviewer —ACC/AHA Task Force onPractice GuidelinesNorthwestern UniversityFeinberg School of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Vice Dean for Diversity andInclusion, Chief of Medicine-Cardiology, and Professor?. ### Response: Clyde W. Yancy Content Reviewer —ACC/AHA Task Force onPractice GuidelinesNorthwestern UniversityFeinberg School of Medicine.


Instruction: What is a person deemed to have a signi ficant interest in?

Output: a business

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a person deemed to have a signi ficant interest in?. ### Response: a business.


Instruction: What are the relationships of reviewers with industry?

Output: This table represents the relationships of reviewers with industry and other entities that were disclosed at the time of peer review and determined to be relevant to this document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the relationships of reviewers with industry?. ### Response: This table represents the relationships of reviewers with industry and other entities that were disclosed at the time of peer review and determined to be relevant to this document.


Instruction: How much of the voting stock or share of a business is a person deemed to have a signi ficant interest in?

Output: $5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the voting stock or share of a business is a person deemed to have a signi ficant interest in?. ### Response: $5%.


Instruction: What is the amount of ownership of the fair market value of the business entity?

Output: $$5,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the amount of ownership of the fair market value of the business entity?. ### Response: $$5,000.


Instruction: How much of the person's gross income does the business entity receive?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the person's gross income does the business entity receive?. ### Response: 5%.


Instruction: What is a relationship considered modest if it is less than signi ficant under the preceding de finition?

Output: Relationships that exist with no ﬁnancialbeneﬁ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered modest if it is less than signi ficant under the preceding de finition?. ### Response: Relationships that exist with no ﬁnancialbeneﬁ.


Instruction: Relationships that exist with no financial benefit are considered what?

Output: transparency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Relationships that exist with no financial benefit are considered what?. ### Response: transparency.


Instruction: What are relationships that exist with no financial benefit included for the purpose of transparency?

Output: ﬁnancialbeneﬁt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are relationships that exist with no financial benefit included for the purpose of transparency?. ### Response: ﬁnancialbeneﬁt.


Instruction: Relationships in this table are modest unless what is noted?

Output: otherwise noted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Relationships in this table are modest unless what is noted?. ### Response: otherwise noted.


Instruction: Names are listed in alphabetical o rder within each category of what?

Output: review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Names are listed in alphabetical o rder within each category of what?. ### Response: review.


Instruction: Who has a relevant relationship with?

Output: a person

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has a relevant relationship with?. ### Response: a person.


Instruction: Who makes a drug, drug class, or device?

Output: h e company/entity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who makes a drug, drug class, or device?. ### Response: h e company/entity.


Instruction: What is the ACC/AHA?

Output: Task Force onPractice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA?. ### Response: Task Force onPractice Guidelines.


Instruction: Who makes a drug, drug class, or device addressed in the document?

Output: company/entity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who makes a drug, drug class, or device addressed in the document?. ### Response: company/entity.


Instruction: Who has a reasonable potential for financial,professional, or other personal gain?

Output: the person or a member of the person ’s household

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has a reasonable potential for financial,professional, or other personal gain?. ### Response: the person or a member of the person ’s household.


Instruction: What is the acronym for American College of Cardiology?

Output: ACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American College of Cardiology?. ### Response: ACC.


Instruction: What is a acronym for Society for Cardiovascular Angiography and Interventions?

Output: SCAI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a acronym for Society for Cardiovascular Angiography and Interventions?. ### Response: SCAI.


Instruction: What is the acronym for ST-elevation myocardial infarction?

Output: S TEMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for ST-elevation myocardial infarction?. ### Response: S TEMI.


Instruction: What is TIMI?

Output: ThrombolysisIn Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TIMI?. ### Response: ThrombolysisIn Myocardial Infarction.


Instruction: What was the 2013 ACCF/AHA STEMI Guideline e373survival in a population with a relatively low mortality rate?

Output: improved early survival of higher-risk patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2013 ACCF/AHA STEMI Guideline e373survival in a population with a relatively low mortality rate?. ### Response: improved early survival of higher-risk patients.


Instruction: What is the goal of comprehensive efforts to improve all aspects of acute MI care?

Output: improve survival rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of comprehensive efforts to improve all aspects of acute MI care?. ### Response: improve survival rates.


Instruction: What can be short-ened by administration of prehospital fibrinolytic therapy?

Output: STEMI mor -tality rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be short-ened by administration of prehospital fibrinolytic therapy?. ### Response: STEMI mor -tality rates.


Instruction: How can time delay from symptom onset to treatment be shortened?

Output: prehospital versus hospital-based administration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can time delay from symptom onset to treatment be shortened?. ### Response: prehospital versus hospital-based administration.


Instruction: How long have RCTs shown the safety and feasibility of prehospital fibrino-lytic therapy?

Output: 30 to 140 minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long have RCTs shown the safety and feasibility of prehospital fibrino-lytic therapy?. ### Response: 30 to 140 minutes.


Instruction: What are the reduced treatment times of fibrineolytic therapy ranging from 30 to 140 minutes?

Output: 42,143,145–147,149–151,153

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the reduced treatment times of fibrineolytic therapy ranging from 30 to 140 minutes?. ### Response: 42,143,145–147,149–151,153.


Instruction: How long did a meta-analysis of 6 higher-quality RCT's reveal?

Output: approximately 60-minute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did a meta-analysis of 6 higher-quality RCT's reveal?. ### Response: approximately 60-minute.


Instruction: How long did higher quality RCTs show a reduction in time from symptom onset to delivery of fibrinolytic therapy?

Output: 60-minute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did higher quality RCTs show a reduction in time from symptom onset to delivery of fibrinolytic therapy?. ### Response: 60-minute.


Instruction: What was the reduction in risk of all-cause hospital mortality?

Output: 17%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in risk of all-cause hospital mortality?. ### Response: 17%.


Instruction: What was the 5-year mortality rate for patients treated with prehospital fibrinolysis compared to patients managed with primary PCI?

Output: P=0.04

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 5-year mortality rate for patients treated with prehospital fibrinolysis compared to patients managed with primary PCI?. ### Response: P=0.04.


Instruction: How long after symptom onset did patients enrolled in the CAPTIM trial have a significantly lower mortality rate?

Output: 2 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after symptom onset did patients enrolled in the CAPTIM trial have a significantly lower mortality rate?. ### Response: 2 hours.


Instruction: What two trials confirmed the salutary results for early presenters?

Output: CAPTIM and WEST

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What two trials confirmed the salutary results for early presenters?. ### Response: CAPTIM and WEST.


Instruction: What do the CAPTIM and WEST trials do?

Output: lower 5-year mortality rate for patients treated with prehospital fibrinolysis than for patients managed with primary PCI (P=0.04).123,142 These salutary results for early presenters were confirmed in a subsequent analysis of com-bined data from the CAPTIM and WEST (Which Early ST-Elevation Myocardial Infarction Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the CAPTIM and WEST trials do?. ### Response: lower 5-year mortality rate for patients treated with prehospital fibrinolysis than for patients managed with primary PCI (P=0.04).123,142 These salutary results for early presenters were confirmed in a subsequent analysis of com-bined data from the CAPTIM and WEST (Which Early ST-Elevation Myocardial Infarction Therapy.


Instruction: Data from the USIC and Swedish Registry suggest what?

Output: prehospital fibrinolytic therapy may lower STEMI mor -tality rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data from the USIC and Swedish Registry suggest what?. ### Response: prehospital fibrinolytic therapy may lower STEMI mor -tality rates.


Instruction: What does the Registry of Cardiac Intensive Care suggest may lower STEMI mor -tality rates?

Output: prehospital fibrinolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Registry of Cardiac Intensive Care suggest may lower STEMI mor -tality rates?. ### Response: prehospital fibrinolytic therapy.


Instruction: Prehospital fibrinolytic ther-apy is not used in most communities in what country?

Output: United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prehospital fibrinolytic ther-apy is not used in most communities in what country?. ### Response: United States.


Instruction: What is more widespread in some regions of Europe and the United Kingdom?

Output: Use of prehospital fibrinolysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more widespread in some regions of Europe and the United Kingdom?. ### Response: Use of prehospital fibrinolysis.


Instruction: The writing committee endorses the need for further research into what?

Output: the implementation of prehospital strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The writing committee endorses the need for further research into what?. ### Response: the implementation of prehospital strategies.


Instruction: What should be started as soon as possible in comatose patients?

Output: Therapeutic hypothermia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be started as soon as possible in comatose patients?. ### Response: Therapeutic hypothermia.


Instruction: What is the relationship between Sudden Cardiac Death and STEMI?

Output: 3.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between Sudden Cardiac Death and STEMI?. ### Response: 3.6.