Instruction: What did the ONTARGET trial show in a population at high risk of CVD?

Output: increased risk of majorrenal outcomes with dual RAAS blockade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ONTARGET trial show in a population at high risk of CVD?. ### Response: increased risk of majorrenal outcomes with dual RAAS blockade.


Instruction: What was shown to be an increased risk of majorrenal outcomes with dual RAAS blockade?

Output: CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was shown to be an increased risk of majorrenal outcomes with dual RAAS blockade?. ### Response: CVD.


Instruction: What did the ALTITUDE trial randomized type 2 diabetic patients to receive?

Output: aliskiren or matching placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ALTITUDE trial randomized type 2 diabetic patients to receive?. ### Response: aliskiren or matching placebo.


Instruction: What was the name of the trial that randomized diabetic participants to receive aliskiren or matching placebo?

Output: ALTITUDE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the trial that randomized diabetic participants to receive aliskiren or matching placebo?. ### Response: ALTITUDE.


Instruction: What did the participants receive on top of an ACE-I or ARB113?

Output: aliskiren or matching placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the participants receive on top of an ACE-I or ARB113?. ### Response: aliskiren or matching placebo.


Instruction: Why was the trial stopped early?

Output: low likelihood of everdemonstrating beneﬁt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the trial stopped early?. ### Response: low likelihood of everdemonstrating beneﬁt.


Instruction: What was the US FDA counseled against?

Output: this practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the US FDA counseled against?. ### Response: this practice.


Instruction: What is one of the adverse outcomes of this practice?

Output: non-fatal stroke, renalcomplications, hyperkalemia and hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the adverse outcomes of this practice?. ### Response: non-fatal stroke, renalcomplications, hyperkalemia and hypotension.


Instruction: What is the setting of protein-losing enteropathy poorly re-sponsive to?

Output: other therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the setting of protein-losing enteropathy poorly re-sponsive to?. ### Response: other therapies.


Instruction: Budesonide seems to have fewer systemic effects than what other oral steroids?

Output: protein-losing enteropathy poorly re-sponsive to other therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Budesonide seems to have fewer systemic effects than what other oral steroids?. ### Response: protein-losing enteropathy poorly re-sponsive to other therapies.


Instruction: What may be con-sidered?

Output: S4.4.2-28,S4.4.2-29 Octreotide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be con-sidered?. ### Response: S4.4.2-28,S4.4.2-29 Octreotide.


Instruction: What type of surgery has been associated with prolonga-tion of atrial refractory periods?

Output: Fontan surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery has been associated with prolonga-tion of atrial refractory periods?. ### Response: Fontan surgery.


Instruction: What has been associated with prolonged atrial refractory periods, extensive atrial scar ring, and intra-atrial conduction delay?

Output: Fontan surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been associated with prolonged atrial refractory periods, extensive atrial scar ring, and intra-atrial conduction delay?. ### Response: Fontan surgery.


Instruction: Si-nus node dysfunction occurs in up to 45% of adults during long-term follow-up after Fontan surgery?

Output: S4.4.2-32–S4.4.2-38

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Si-nus node dysfunction occurs in up to 45% of adults during long-term follow-up after Fontan surgery?. ### Response: S4.4.2-32–S4.4.2-38.


Instruction: Preload to the single ventricle, increased pulmonary venous pressure, reduced cardiac output, plastic bronchitis, and what else?

Output: protein-losing enteropathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preload to the single ventricle, increased pulmonary venous pressure, reduced cardiac output, plastic bronchitis, and what else?. ### Response: protein-losing enteropathy.


Instruction: Transvenous atrial pacing may be feasible in most adults with atrio-pulmonary Fontan connections and in some adults with intra-cardiac lateral tunnels.

Output: S4.4.2-39–S4.4.2-43

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Transvenous atrial pacing may be feasible in most adults with atrio-pulmonary Fontan connections and in some adults with intra-cardiac lateral tunnels.. ### Response: S4.4.2-39–S4.4.2-43.


Instruction: What must be addressed for thrombotic complications?

Output: the potential

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be addressed for thrombotic complications?. ### Response: the potential.


Instruction: Ventricular pacing may be performed via what?

Output: coronary sinus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ventricular pacing may be performed via what?. ### Response: coronary sinus.


Instruction: Most patients require what approach?

Output: epicardial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most patients require what approach?. ### Response: epicardial.


Instruction: Management of atrial arrhyth-mias is discussed in what section?

Output: the associated recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Management of atrial arrhyth-mias is discussed in what section?. ### Response: the associated recommendations.


Instruction: How many adults with Fontan palliation have atrial tachyarrhythmias?

Output: up to 60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many adults with Fontan palliation have atrial tachyarrhythmias?. ### Response: up to 60%.


Instruction: What is Section 3.4 for?

Output: rec-ommendations on diagnostic evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Section 3.4 for?. ### Response: rec-ommendations on diagnostic evaluation.


Instruction: Table 32 for routine testing and follow up intervals.

Output: atrial arrhyth-mias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Table 32 for routine testing and follow up intervals.. ### Response: atrial arrhyth-mias.


Instruction: What are adults with Fontan palliation associated with?

Output: substantial morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are adults with Fontan palliation associated with?. ### Response: substantial morbidity and mortality.


Instruction: What is difficult to manage, is usually poorly tolerated, and causes serious hemodynamic compromise?

Output: Atrial tachyarrhythmias occur in up to 60% of adults with Fontan palliation and are associated with substantial morbidity and mortality.S4.4.2-2 These arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is difficult to manage, is usually poorly tolerated, and causes serious hemodynamic compromise?. ### Response: Atrial tachyarrhythmias occur in up to 60% of adults with Fontan palliation and are associated with substantial morbidity and mortality.S4.4.2-2 These arrhythmias.


Instruction: Who can help guide immediate management of arrhythmias?

Output: ACHD provid-ers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who can help guide immediate management of arrhythmias?. ### Response: ACHD provid-ers.


Instruction: Who can help guide immediate management strategies even if remotely?

Output: ACHD provid-ers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who can help guide immediate management strategies even if remotely?. ### Response: ACHD provid-ers.


Instruction: What should Fontan patients consider when considering anti-thrombotic therapy?

Output: high prevalence of thrombus for -mation and potentially catastrophic impact of pul-monary or systemic thromboembolus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should Fontan patients consider when considering anti-thrombotic therapy?. ### Response: high prevalence of thrombus for -mation and potentially catastrophic impact of pul-monary or systemic thromboembolus.


Instruction: What is thromboembolus?

Output: pul-monary or systemic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is thromboembolus?. ### Response: pul-monary or systemic.


Instruction: What is the name of the standard recommendations for Fontan Palliation of Single Ventricle Physiology?

Output: COR LOE Recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the standard recommendations for Fontan Palliation of Single Ventricle Physiology?. ### Response: COR LOE Recommendations.


Instruction: How many cases of e364 Stroke were included in the AHA GWTG-Stroke registry?

Output: 832

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of e364 Stroke were included in the AHA GWTG-Stroke registry?. ### Response: 832.


Instruction: How many patients with sickle cell disease had a case-control analysis?

Output: 832

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with sickle cell disease had a case-control analysis?. ### Response: 832.


Instruction: How many cases of sickle cell disease were there in the AHA GWTG-Stroke registry?

Output: 832

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of sickle cell disease were there in the AHA GWTG-Stroke registry?. ### Response: 832.


Instruction: How many adults had sickle cells?

Output: 832

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many adults had sickle cells?. ### Response: 832.


Instruction: What did the registry show?

Output: sickle cell disease did not have a significant impact on the safety or the outcome at discharge of treatment with IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the registry show?. ### Response: sickle cell disease did not have a significant impact on the safety or the outcome at discharge of treatment with IV alteplase.


Instruction: Who were the 3328 controls with similar neurological deficits?

Output: age-, sex-, and race-matched controls without sickle cell disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were the 3328 controls with similar neurological deficits?. ### Response: age-, sex-, and race-matched controls without sickle cell disease.


Instruction: What is a significant impact on the safety or the outcome at discharge of treatment with IV alteplase?

Output: increased risk of sICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a significant impact on the safety or the outcome at discharge of treatment with IV alteplase?. ### Response: increased risk of sICH.


Instruction: What can be beneficial in patients with a hyperdense MCA sign?

Output: IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial in patients with a hyperdense MCA sign?. ### Response: IV alteplase.


Instruction: Data from RCTs of IV alteplase for AIS have shown what?

Output: no statistically significant deleterious interaction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data from RCTs of IV alteplase for AIS have shown what?. ### Response: no statistically significant deleterious interaction.


Instruction: In the NINDS rt-PA trial, there was no interaction between hyperdense MCA sign and treatment for outcomes at 3 months measured?

Output: by any of the 4 clinical scales

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the NINDS rt-PA trial, there was no interaction between hyperdense MCA sign and treatment for outcomes at 3 months measured?. ### Response: by any of the 4 clinical scales.


Instruction: How many clinical scales measure MCA sign and treatment for outcomes at 3 months?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many clinical scales measure MCA sign and treatment for outcomes at 3 months?. ### Response: 4.


Instruction: What is the Glasgow Outcome Scale score 95?

Output: 94

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Glasgow Outcome Scale score 95?. ### Response: 94.


Instruction: In IST-3, no significant interaction of hyperdense MCA signs with benefit of alteplase measured?

Output: Oxford Handicap Score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In IST-3, no significant interaction of hyperdense MCA signs with benefit of alteplase measured?. ### Response: Oxford Handicap Score.


Instruction: What was the hyperdense MCA sign with benefit of alteplase measured by the Oxford Handicap Score at 6 months?

Output: no significant interaction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the hyperdense MCA sign with benefit of alteplase measured by the Oxford Handicap Score at 6 months?. ### Response: no significant interaction.


Instruction: What is the extremely low risk of unsuspected abnormal platelet counts?

Output: coagulation studies in a population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the extremely low risk of unsuspected abnormal platelet counts?. ### Response: coagulation studies in a population.


Instruction: What is the risk of unsuspected abnormal platelet counts or coagulation studies in a population?

Output: extremely low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of unsuspected abnormal platelet counts or coagulation studies in a population?. ### Response: extremely low.


Instruction: What is reasonable that urgent IV alteplase treatment not be delayed while waiting for?

Output: hematologic or coagulation testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable that urgent IV alteplase treatment not be delayed while waiting for?. ### Response: hematologic or coagulation testing.


Instruction: B-NRRecommendation and COR unchanged from what year?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: B-NRRecommendation and COR unchanged from what year?. ### Response: 2015.


Instruction: LOE amended to conform with what system?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LOE amended to conform with what system?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: In otherwise eligible patients who have previously had a small number of CMBs demonstrated on MRI, administration of IV alteplase is reasonable.

Output: In patients with a hyperdense MCA sign

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In otherwise eligible patients who have previously had a small number of CMBs demonstrated on MRI, administration of IV alteplase is reasonable.. ### Response: In patients with a hyperdense MCA sign.


Instruction: Is IV alteplase associated with an increased risk of sICH?

Output: In otherwise eligible patients who have previously had a high burden of CMBs (>10) demonstrated on MRI, treatment with IV alteplase may be associated with an increased risk of sICH, and the benefits of treatment are uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is IV alteplase associated with an increased risk of sICH?. ### Response: In otherwise eligible patients who have previously had a high burden of CMBs (>10) demonstrated on MRI, treatment with IV alteplase may be associated with an increased risk of sICH, and the benefits of treatment are uncertain.


Instruction: What may be reasonable if there is a high burden of CMBs?

Output: Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable if there is a high burden of CMBs?. ### Response: Treatment.


Instruction: What percentage of patients receiving IV alteplase have CMBs?

Output: 15% to 27%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients receiving IV alteplase have CMBs?. ### Response: 15% to 27%..


Instruction: No RCTs have been conducted with baseline MRI to identify what?

Output: CMBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No RCTs have been conducted with baseline MRI to identify what?. ### Response: CMBs.


Instruction: How many meta-analyses of the association of baseline CMBs on the risk of sICH after IV alteplase reported that sich is more common?

Output: Two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many meta-analyses of the association of baseline CMBs on the risk of sICH after IV alteplase reported that sich is more common?. ### Response: Two.


Instruction: What is more common in patients with baseline CMBs?

Output: sICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more common in patients with baseline CMBs?. ### Response: sICH.


Instruction: What did 2 other meta-analyses and 1 multicenter study not show?

Output: statistically significant deleterious interaction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did 2 other meta-analyses and 1 multicenter study not show?. ### Response: statistically significant deleterious interaction.


Instruction: What is the difference between rivaroxaban and warfarin in patients with non-valvular atrial fibrillation and moder-ate renal impairment?

Output: Prevention of stroke and systemic embolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between rivaroxaban and warfarin in patients with non-valvular atrial fibrillation and moder-ate renal impairment?. ### Response: Prevention of stroke and systemic embolism.


Instruction: What drug is used to prevent stroke and systemic embolism?

Output: rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used to prevent stroke and systemic embolism?. ### Response: rivaroxaban.


Instruction: Atrial fibrillation and moder ate renal impairment.

Output: 399. Fox KA, Piccini JP, Wojdyla D, Becker RC, Halperin JL, Nessel CC, Paolini JF, Hankey GJ, Mahaffey KW, Patel MR, Singer DE, Califf RM. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moder -ate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation and moder ate renal impairment.. ### Response: 399. Fox KA, Piccini JP, Wojdyla D, Becker RC, Halperin JL, Nessel CC, Paolini JF, Hankey GJ, Mahaffey KW, Patel MR, Singer DE, Califf RM. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moder -ate.


Instruction: Eur Heart J. 2011;32:2387–2394.

Output: 399

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Eur Heart J. 2011;32:2387–2394.. ### Response: 399.


Instruction: Fleming TR, Emerson SS. Evaluating rivaroxaban for nonvalvu-lar atrial fibrosis: regulatory considerations.

Output: Lanas-Zanetti F, Gonzalez-Hermosillo A, Dans AL, Munawar M, O’Donnell M, Lawrence J, Lewis G, Afzal R, Yusuf S; A VERROES Steering Committee and Investigators. Apixaban in patients with atrial fibrillation. N Engl J Med. 2011;364:806–817

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fleming TR, Emerson SS. Evaluating rivaroxaban for nonvalvu-lar atrial fibrosis: regulatory considerations.. ### Response: Lanas-Zanetti F, Gonzalez-Hermosillo A, Dans AL, Munawar M, O’Donnell M, Lawrence J, Lewis G, Afzal R, Yusuf S; A VERROES Steering Committee and Investigators. Apixaban in patients with atrial fibrillation. N Engl J Med. 2011;364:806–817.


Instruction: N Engl J Med 2011;365:1557–1559.

Output: 399. Fox KA, Piccini JP, Wojdyla D, Becker RC, Halperin JL, Nessel CC, Paolini JF, Hankey GJ, Mahaffey KW, Patel MR, Singer DE, Califf RM. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moder -ate renal impairment. Eur Heart J. 2011;32:2387–2394. 400. Fleming TR, Emerson SS. Evaluating rivaroxaban for nonvalvu-lar atrial fibrillation: regulatory considerations. N Engl J Med. 2011;365:1557–1559. 401

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: N Engl J Med 2011;365:1557–1559.. ### Response: 399. Fox KA, Piccini JP, Wojdyla D, Becker RC, Halperin JL, Nessel CC, Paolini JF, Hankey GJ, Mahaffey KW, Patel MR, Singer DE, Califf RM. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moder -ate renal impairment. Eur Heart J. 2011;32:2387–2394. 400. Fleming TR, Emerson SS. Evaluating rivaroxaban for nonvalvu-lar atrial fibrillation: regulatory considerations. N Engl J Med. 2011;365:1557–1559. 401.


Instruction: What is the name of the person who wrote this article?

Output: Connolly SJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who wrote this article?. ### Response: Connolly SJ.


Instruction: What is one of the names of the people who worked on this article in the past?

Output: Fox KA, Piccini JP, Wojdyla D, Becker RC, Halperin JL, Nessel CC, Paolini JF, Hankey GJ, Mahaffey KW, Patel MR, Singer DE, Califf RM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the names of the people who worked on this article in the past?. ### Response: Fox KA, Piccini JP, Wojdyla D, Becker RC, Halperin JL, Nessel CC, Paolini JF, Hankey GJ, Mahaffey KW, Patel MR, Singer DE, Califf RM.


Instruction: Who is the author of the article in which this article was written?

Output: Connolly SJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the article in which this article was written?. ### Response: Connolly SJ.


Instruction: What is Apixaban used for in patients with atrial fibrillation?

Output: regulatory considerations. N Engl J Med. 2011;365:1557–1559. 401. Connolly SJ, Eikelboom J, Joyner C, Diener HC, Hart R, Golitsyn S, Flaker G, Avezum A, Hohnloser SH, Diaz R, Talajic M, Zhu J, Pais P, Budaj A, Parkhomenko A, Jansky P, Commerford P, Tan RS, Sim KH, Lewis BS, Van Mieghem W, Lip GY , Kim JH, Lanas-Zanetti F, Gonzalez-Hermosillo A, Dans AL, Munawar M, O’Donnell M, Lawrence J, Lewis G, Afzal R, Yusuf S; A VERROES Steering Committee and Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Apixaban used for in patients with atrial fibrillation?. ### Response: regulatory considerations. N Engl J Med. 2011;365:1557–1559. 401. Connolly SJ, Eikelboom J, Joyner C, Diener HC, Hart R, Golitsyn S, Flaker G, Avezum A, Hohnloser SH, Diaz R, Talajic M, Zhu J, Pais P, Budaj A, Parkhomenko A, Jansky P, Commerford P, Tan RS, Sim KH, Lewis BS, Van Mieghem W, Lip GY , Kim JH, Lanas-Zanetti F, Gonzalez-Hermosillo A, Dans AL, Munawar M, O’Donnell M, Lawrence J, Lewis G, Afzal R, Yusuf S; A VERROES Steering Committee and Investigators.


Instruction: What is the name of the Steering Committee and Investigators of AVERROES?

Output: A VERROES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Steering Committee and Investigators of AVERROES?. ### Response: A VERROES.


Instruction: What is the name of the journal that studies the role of surgeons in mitral valve repair?

Output: JACC Cardiovasc Interv.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the role of surgeons in mitral valve repair?. ### Response: JACC Cardiovasc Interv..


Instruction: What year did Ann Thorac Surg publish its 90th issue?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Thorac Surg publish its 90th issue?. ### Response: 2010.


Instruction: Why is noninferiority of closely moni-tored mechanical valves overshadowed by early mortality benefit in younger patients?

Output: bioprostheses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is noninferiority of closely moni-tored mechanical valves overshadowed by early mortality benefit in younger patients?. ### Response: bioprostheses.


Instruction: What is overshadowed by early mortality benefit in younger patients?

Output: Noninferiority of closely moni-tored mechanical valves to bioprostheses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is overshadowed by early mortality benefit in younger patients?. ### Response: Noninferiority of closely moni-tored mechanical valves to bioprostheses.


Instruction: What is Pulmonary hypertension and elevat-ed transpulmonary gradient in patients with mitral stenosis?

Output: rasuski

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Pulmonary hypertension and elevat-ed transpulmonary gradient in patients with mitral stenosis?. ### Response: rasuski.


Instruction: When did J Heart Valve Dis. 2010:19:708–15?

Output: 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Heart Valve Dis. 2010:19:708–15?. ### Response: 27.


Instruction: What is the relationship between surgical volume, repair quality, and perioperative outcomes for repair of mitral in-sufficiency in a mitral valve reference center?

Output: repair rate, durability, and survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between surgical volume, repair quality, and perioperative outcomes for repair of mitral in-sufficiency in a mitral valve reference center?. ### Response: repair rate, durability, and survival.


Instruction: What does LaPar DJ, Ailawadi G, Isbell JM, et al. do?

Output: Mitral valve repair rates correlate with surgeon and institutional experience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LaPar DJ, Ailawadi G, Isbell JM, et al. do?. ### Response: Mitral valve repair rates correlate with surgeon and institutional experience.


Instruction: What do mitral valve repair rates correlate with?

Output: surgeon and institutional experience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do mitral valve repair rates correlate with?. ### Response: surgeon and institutional experience.


Instruction: What does JM, Conte, and Kilic A, Shah AS, and Conte JV, et al. do?

Output: Operative outcomes in mitral valve sur -gery: combined effect of surgeon and hospital volume in a population-based analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does JM, Conte, and Kilic A, Shah AS, and Conte JV, et al. do?. ### Response: Operative outcomes in mitral valve sur -gery: combined effect of surgeon and hospital volume in a population-based analysis.


Instruction: What does volume in a population-based analysis do?

Output: Operative outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does volume in a population-based analysis do?. ### Response: Operative outcomes.


Instruction: What is the effect of procedural volume on care process and mortality for patients undergoing elective surgery for mitral regurgitation?

Output: Influence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of procedural volume on care process and mortality for patients undergoing elective surgery for mitral regurgitation?. ### Response: Influence.


Instruction: How many patients were treated with mitral valve surgery in 2015?

Output: 32

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with mitral valve surgery in 2015?. ### Response: 32.


Instruction: What is the name of the study that analyzed US hospitals treating Medicare fee-for-service patients?

Output: J Thorac Cardiovasc Surg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that analyzed US hospitals treating Medicare fee-for-service patients?. ### Response: J Thorac Cardiovasc Surg.


Instruction: What is the relation of mitral valve surgery volume to repair rate, durability, and survival?

Output: perioperative outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relation of mitral valve surgery volume to repair rate, durability, and survival?. ### Response: perioperative outcomes.


Instruction: What was the J Am Coll Cardiol. 2017;69:2397–406.

Output: Relation of mitral valve sur -gery volume to repair rate, durability, and survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol. 2017;69:2397–406.. ### Response: Relation of mitral valve sur -gery volume to repair rate, durability, and survival.


Instruction: What did Chhatriwalla AK, Vemulapalli S, Holmes DR Jr, et al. do?

Output: Institutional experi-ence with transcatheter mitral valve repair and clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Chhatriwalla AK, Vemulapalli S, Holmes DR Jr, et al. do?. ### Response: Institutional experi-ence with transcatheter mitral valve repair and clinical outcomes.


Instruction: What does the TVT registry provide insights into?

Output: Institutional experi-ence with transcatheter mitral valve repair and clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the TVT registry provide insights into?. ### Response: Institutional experi-ence with transcatheter mitral valve repair and clinical outcomes.


Instruction: What is the JACC Cardiovasc Interv. 2019;12:1342–52?

Output: Institutional experi-ence with transcatheter mitral valve repair and clinical outcomes: insights from the TVT registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JACC Cardiovasc Interv. 2019;12:1342–52?. ### Response: Institutional experi-ence with transcatheter mitral valve repair and clinical outcomes: insights from the TVT registry.


Instruction: Who is the author of Progress in development of the index of ADL?

Output: Katz

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Progress in development of the index of ADL?. ### Response: Katz.


Instruction: What is a global clinical measure of fitness and frailty in elderly people?

Output: Knight C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a global clinical measure of fitness and frailty in elderly people?. ### Response: Knight C.


Instruction: What is the name of the multidisciplinary team and heart valve centers?

Output: Multidisciplinary Heart Valve Team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multidisciplinary team and heart valve centers?. ### Response: Multidisciplinary Heart Valve Team.


Instruction: Surgeon volume and operative mortality in the United States.

Output: The Multidisciplinary Heart Valve Team and Heart Valve Centers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Surgeon volume and operative mortality in the United States.. ### Response: The Multidisciplinary Heart Valve Team and Heart Valve Centers.


Instruction: What year was the N Engl J Med 349:2117-27?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the N Engl J Med 349:2117-27?. ### Response: 2003.


Instruction: What is the name of the statewide cardiac surgical database used to identify a procedural volume hinge point?

Output: TVT registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the statewide cardiac surgical database used to identify a procedural volume hinge point?. ### Response: TVT registry.


Instruction: Who is the author of Aortic valve replacement?

Output: Patel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Aortic valve replacement?. ### Response: Patel.


Instruction: What is the effect of hospital volume on prosthetic outcomes with aortic valve replacement?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of hospital volume on prosthetic outcomes with aortic valve replacement?. ### Response: mortality.


Instruction: What year did Ann Thorac Surg publish 93:1107-12?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Thorac Surg publish 93:1107-12?. ### Response: 2012.


Instruction: What is MOde Selection Trial?

Output: MOST

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MOde Selection Trial?. ### Response: MOST.


Instruction: What predicts arterial embolic events in patients suffering frombradycardia?

Output: Monitored atrial ﬁbrillationduration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts arterial embolic events in patients suffering frombradycardia?. ### Response: Monitored atrial ﬁbrillationduration.


Instruction: What is the relationship between daily atrial tachyarrhythmia burden from implantable devicediagnostics and stroke risk?

Output: TRENDS study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between daily atrial tachyarrhythmia burden from implantable devicediagnostics and stroke risk?. ### Response: TRENDS study.


Instruction: What did the TRENDS study look at?

Output: The relationship betweendaily atrial tachyarrhythmia burden from implantable devicediagnostics and stroke risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the TRENDS study look at?. ### Response: The relationship betweendaily atrial tachyarrhythmia burden from implantable devicediagnostics and stroke risk.


Instruction: What was the name of the study that looked at atrial tachyarrhythmia burden and stroke risk?

Output: TRENDS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that looked at atrial tachyarrhythmia burden and stroke risk?. ### Response: TRENDS.


Instruction: When was the Circ ArrhythmElectrophysiol 2(5):474-480.384?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circ ArrhythmElectrophysiol 2(5):474-480.384?. ### Response: 2009.


Instruction: How was the Detection of atrial high rate events measured?

Output: continuous home monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the Detection of atrial high rate events measured?. ### Response: continuous home monitoring.


Instruction: How many patients were analyzed from the SOS AF project?

Output: >10,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were analyzed from the SOS AF project?. ### Response: >10,000.


Instruction: What is the name of the project that measures atrial fibrillation and stroke risk?

Output: SOS AF project

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the project that measures atrial fibrillation and stroke risk?. ### Response: SOS AF project.


Instruction: What predicts long-term mortality outcomes in patients with permanent pacemakers?

Output: atrialhigh rate episodes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts long-term mortality outcomes in patients with permanent pacemakers?. ### Response: atrialhigh rate episodes.


Instruction: What does early detection of atrial high rate episodes predict?

Output: atrial ﬁbrillation and thromboembolic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does early detection of atrial high rate episodes predict?. ### Response: atrial ﬁbrillation and thromboembolic events.


Instruction: What predicts atrial fibrillation and thromboembolic events in patients withcardiac resynchronization therapy?

Output: Early detection of atrial high rate episodes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts atrial fibrillation and thromboembolic events in patients withcardiac resynchronization therapy?. ### Response: Early detection of atrial high rate episodes.


Instruction: When did Heart Rhythm publish its 12(12):2368-2375?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Heart Rhythm publish its 12(12):2368-2375?. ### Response: 2015.


Instruction: How did Van Gelder, Healey, and Crijns compare to ASSERT?

Output: Duration of device-detected subclinical atrial ﬁbrillation and occurrence of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Van Gelder, Healey, and Crijns compare to ASSERT?. ### Response: Duration of device-detected subclinical atrial ﬁbrillation and occurrence of stroke.


Instruction: In what year did Eur Heart J issue 38(17):1339-1344.389?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Eur Heart J issue 38(17):1339-1344.389?. ### Response: 2017.


Instruction: What are the CHADS2 and CHA2DS2-VASc risk scores used for in patients with paroxysmal atrial fibrillation?

Output: Improving stroke riskstrati ﬁcation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the CHADS2 and CHA2DS2-VASc risk scores used for in patients with paroxysmal atrial fibrillation?. ### Response: Improving stroke riskstrati ﬁcation.


Instruction: What drug is used for the reduction of thrombo-embolism in patients with device-detected sub-clinical atrial fibrillation?

Output: Apixaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used for the reduction of thrombo-embolism in patients with device-detected sub-clinical atrial fibrillation?. ### Response: Apixaban.


Instruction: What is ARTESiA?

Output: Device-Detected Sub-Clinical Atrial Fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ARTESiA?. ### Response: Device-Detected Sub-Clinical Atrial Fibrillation.


Instruction: What is the name of the NOAH-AFNET 6) trial?

Output: Atrial High rate episodes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the NOAH-AFNET 6) trial?. ### Response: Atrial High rate episodes.


Instruction: What is a risk of thromboembolic events in patients with atrial high rate episodes?

Output: atrial ﬁbrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk of thromboembolic events in patients with atrial high rate episodes?. ### Response: atrial ﬁbrillation.


Instruction: What is the risk of thromboembolic events in patients with atrial flutter?

Output: 393

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of thromboembolic events in patients with atrial flutter?. ### Response: 393.


Instruction: What was the Am J Cardiol.1998;82(5):580-583.393?

Output: Risk ofthromboembolic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Am J Cardiol.1998;82(5):580-583.393?. ### Response: Risk ofthromboembolic events.


Instruction: Corrado G, Sgalambro A, Mantero A, et al.

Output: Thromboembolic risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Corrado G, Sgalambro A, Mantero A, et al.. ### Response: Thromboembolic risk.


Instruction: What is considered to be a cause of increased stroke in pregnancy?

Output: future hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered to be a cause of increased stroke in pregnancy?. ### Response: future hypertension.


Instruction: What is the class of side effects of methyldopa and labetalol?

Output: Class I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of side effects of methyldopa and labetalol?. ### Response: Class I.


Instruction: What are effective antihypertensive medications given the evidence for possibly increased stroke risk?

Output: currently defined systolic and diastolic BP cutoffs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are effective antihypertensive medications given the evidence for possibly increased stroke risk?. ### Response: currently defined systolic and diastolic BP cutoffs.


Instruction: What is evidence for decreased risk for the development of severe hypertension with treatment?

Output: maternal- fetal risk-benefit ratios have not been established

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evidence for decreased risk for the development of severe hypertension with treatment?. ### Response: maternal- fetal risk-benefit ratios have not been established.


Instruction: At what level is Atenolol?

Output: Class III; Level of Evidence C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what level is Atenolol?. ### Response: Class III; Level of Evidence C.


Instruction: What is contraindicated in pregnancy and should not be used?

Output: Atenolol, angiotensin receptor blockers, and direct renin inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is contraindicated in pregnancy and should not be used?. ### Response: Atenolol, angiotensin receptor blockers, and direct renin inhibitors.


Instruction: What should women with chronic hypertension continue on after giving birth?

Output: antihypertensive regi-men

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should women with chronic hypertension continue on after giving birth?. ### Response: antihypertensive regi-men.


Instruction: What should be continued on their antihypertensive regi-men with dosage adjustments to reflect the decrease in volume of distribution and glomerular filtration rate that occurs after delivery?

Output: women with chronic hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be continued on their antihypertensive regi-men with dosage adjustments to reflect the decrease in volume of distribution and glomerular filtration rate that occurs after delivery?. ### Response: women with chronic hypertension.


Instruction: What type of preeclampsia should be carefully monitored for?

Output: postpar -tum

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of preeclampsia should be carefully monitored for?. ### Response: postpar -tum.


Instruction: What is the Level of Evidence C)?

Output: Class IIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence C)?. ### Response: Class IIa.


Instruction: Why is there an increased risk of future hypertension and stroke 1 to 30 years after delivery in women with a history of preeclampsia?

Output: Because of the increased risk of future hypertension and stroke 1 to 30 years after delivery in women with a history of preeclampsia (Level of Evidence B),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there an increased risk of future hypertension and stroke 1 to 30 years after delivery in women with a history of preeclampsia?. ### Response: Because of the increased risk of future hypertension and stroke 1 to 30 years after delivery in women with a history of preeclampsia (Level of Evidence B),.


Instruction: What should all women starting 6 months to 1 year postpartum do?

Output: for a history of pre-eclampsia/eclampsia and document their history of preeclampsia/eclampsia as a risk factor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all women starting 6 months to 1 year postpartum do?. ### Response: for a history of pre-eclampsia/eclampsia and document their history of preeclampsia/eclampsia as a risk factor.


Instruction: What should women do to document their history of pre-eclampsia and document their risk factors?

Output: evaluating all women start-ing 6 months to 1 year post partum

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should women do to document their history of pre-eclampsia and document their risk factors?. ### Response: evaluating all women start-ing 6 months to 1 year post partum.


Instruction: What is a stroke type that is caused by thrombus formation in 1 of the venous sinuses and manifests primarily as headache?

Output: Cerebral Venous ThrombosisCerebral venous thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a stroke type that is caused by thrombus formation in 1 of the venous sinuses and manifests primarily as headache?. ### Response: Cerebral Venous ThrombosisCerebral venous thrombosis.


Instruction: What is the primary manifestation of CVT?

Output: headache

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary manifestation of CVT?. ### Response: headache.


Instruction: What makes up 0.5% to 1% of strokes?

Output: Cerebral Venous ThrombosisCerebral venous thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What makes up 0.5% to 1% of strokes?. ### Response: Cerebral Venous ThrombosisCerebral venous thrombosis.


Instruction: Which type of stroke shows the most prominent differential sex prevalence?

Output: Cerebral Venous Thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which type of stroke shows the most prominent differential sex prevalence?. ### Response: Cerebral Venous Thrombosis.


Instruction: In adulthood, the majority of affected individuals are who?

Output: women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adulthood, the majority of affected individuals are who?. ### Response: women.


Instruction: What percentage of CVT cases are in the majority of studies?

Output: >70%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of CVT cases are in the majority of studies?. ### Response: >70%.


Instruction: What is the overall adult incidence rate for CVT per 100 000 person-years?

Output: 1.32

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the overall adult incidence rate for CVT per 100 000 person-years?. ### Response: 1.32.


Instruction: Which gender is more likely to have CVT than men?

Output: women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which gender is more likely to have CVT than men?. ### Response: women.


Instruction: What is the median age of women in the United States?

Output: 34 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the median age of women in the United States?. ### Response: 34 years.


Instruction: What percentage of women are younger than men in the US?

Output: median age 34 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of women are younger than men in the US?. ### Response: median age 34 years.


Instruction: What is the median age of a woman diagnosed with CVT?

Output: 31 to 50 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the median age of a woman diagnosed with CVT?. ### Response: 31 to 50 years.


Instruction: How old is a man at the time of diagnosis?

Output: 42 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is a man at the time of diagnosis?. ### Response: 42 years.


Instruction: When were guidelines for the evaluation and treatment of CVT published?

Output: recently

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were guidelines for the evaluation and treatment of CVT published?. ### Response: recently.


Instruction: What are the only interim studies with emphasis on sex-specific factors?

Output: Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the only interim studies with emphasis on sex-specific factors?. ### Response: Guidelines.


Instruction: What has been attributed to the female predominance of CVT?

Output: Risk Factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been attributed to the female predominance of CVT?. ### Response: Risk Factors.


Instruction: What is the acronym for the American College of Cardiology?

Output: ACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology?. ### Response: ACC.


Instruction: What does ACC stand for?

Output: American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACC stand for?. ### Response: American College of Cardiology.


Instruction: How long has the ACC been developing documents?

Output: 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has the ACC been developing documents?. ### Response: 2021.


Instruction: When did Maddox and colleagues publish their findings?

Output: FEBRUARY 16, 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Maddox and colleagues publish their findings?. ### Response: FEBRUARY 16, 2021.


Instruction: When was the last update to ECDP for Heart Failure Treatment?

Output: FEBRUARY 16, 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last update to ECDP for Heart Failure Treatment?. ### Response: FEBRUARY 16, 2021.


Instruction: What is the name of the study that studies the association of transthoracic echocardiography findings and long-term outcomes in patients undergo-ing workup of stroke?

Output: meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that studies the association of transthoracic echocardiography findings and long-term outcomes in patients undergo-ing workup of stroke?. ### Response: meta-analysis.


Instruction: What year did J Stroke Cerebrovasc Dis.27:2943–2950?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Stroke Cerebrovasc Dis.27:2943–2950?. ### Response: 2018.


Instruction: What is the name of the study that investigated the feasibility and diagnostic value of cardiovascular magnetic resonance imaging after acute is-chemic stroke of undetermined origin?

Output: Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the feasibility and diagnostic value of cardiovascular magnetic resonance imaging after acute is-chemic stroke of undetermined origin?. ### Response: Stroke.


Instruction: What year did Stroke. 2017;48:1241–1247?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Stroke. 2017;48:1241–1247?. ### Response: 2017.


Instruction: What is the diagnostic yield of transesophageal echocardiography in patients with cryptogenic cerebral ischaemia?

Output: superior

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diagnostic yield of transesophageal echocardiography in patients with cryptogenic cerebral ischaemia?. ### Response: superior.


Instruction: What does Eur J Neurol. 2016;23:569-579?

Output: The diagnostic yield of transesophageal echocardiography in patients with cryptogenic cerebral ischaemia: a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Eur J Neurol. 2016;23:569-579?. ### Response: The diagnostic yield of transesophageal echocardiography in patients with cryptogenic cerebral ischaemia: a meta-analysis.


Instruction: Who is Gaudron M, Bonnaud I, Ros A, Patat F, de Toffol?

Output: B, Giraudeau B, Debiais S

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Gaudron M, Bonnaud I, Ros A, Patat F, de Toffol?. ### Response: B, Giraudeau B, Debiais S.


Instruction: What is the diagnostic and therapeutic value of echocardiography during the acute phase of ischemic stroke?

Output: superior

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diagnostic and therapeutic value of echocardiography during the acute phase of ischemic stroke?. ### Response: superior.


Instruction: What does J Stroke Cerebrovasc Dis. 2014;23:2105-2109?

Output: mic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does J Stroke Cerebrovasc Dis. 2014;23:2105-2109?. ### Response: mic stroke.


Instruction: What is the difference between ech-ocardiography and multidetector cardiac computed tomography in ischaemic stroke patients?

Output: superior

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between ech-ocardiography and multidetector cardiac computed tomography in ischaemic stroke patients?. ### Response: superior.


Instruction: What are the differences between the two methods of cardiac evaluation?

Output: transthoracic ech-ocardiography vs. multidetector cardiac computed tomography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between the two methods of cardiac evaluation?. ### Response: transthoracic ech-ocardiography vs. multidetector cardiac computed tomography.


Instruction: When did Eur J Neurol publish a report on cardiac evaluation in patients with stroke?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Neurol publish a report on cardiac evaluation in patients with stroke?. ### Response: 2012.


Instruction: What is the name of the multicenter clinical trial that uses Org 10172 in Acute Stroke Treatment?

Output: TOAST

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter clinical trial that uses Org 10172 in Acute Stroke Treatment?. ### Response: TOAST.


Instruction: What was the title of the 1993 study?

Output: TOAST: Trial of Org 10172 in Acute Stroke Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the 1993 study?. ### Response: TOAST: Trial of Org 10172 in Acute Stroke Treatment.


Instruction: How many strokes were there in 1993?

Output: 24:35–41

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 1993?. ### Response: 24:35–41.


Instruction: What is acute stroke treatment?

Output: transtho-racic echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is acute stroke treatment?. ### Response: transtho-racic echocardiography.


Instruction: What is the doi: 10.1161/01.str.24.1.35 534?

Output: TOAST: Trial of Org 10172 in Acute Stroke Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1161/01.str.24.1.35 534?. ### Response: TOAST: Trial of Org 10172 in Acute Stroke Treatment.


Instruction: How does transoesophageal echocardiography determine manage-ment in suspected embolic stroke?

Output: The utility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does transoesophageal echocardiography determine manage-ment in suspected embolic stroke?. ### Response: The utility.


Instruction: What is superior to transthoracic echocardiography in management of patients of any age with transient ischemic attack or stroke?

Output: esophageal echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is superior to transthoracic echocardiography in management of patients of any age with transient ischemic attack or stroke?. ### Response: esophageal echocardiography.


Instruction: When did Stroke. 2006;37:2531-2534. doi: 10.1161/01.STR.0000241064.46659.69 537.

Output: esophageal echocardiography is superior to transthoracic echocardiography in management of patients of any age with transient ischemic attack or stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Stroke. 2006;37:2531-2534. doi: 10.1161/01.STR.0000241064.46659.69 537.. ### Response: esophageal echocardiography is superior to transthoracic echocardiography in management of patients of any age with transient ischemic attack or stroke.


Instruction: How many patients with ischemic stroke were examined by transesophageal echocardiography in 2006?

Output: 503

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with ischemic stroke were examined by transesophageal echocardiography in 2006?. ### Response: 503.


Instruction: What are the therapeutic implications of transtho-racic echocardiographic in acute ischematic stroke?

Output: long-term outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the therapeutic implications of transtho-racic echocardiographic in acute ischematic stroke?. ### Response: long-term outcomes.


Instruction: What are the therapy implications of transtho-racic echocardiography in acute ischemic stroke patients?

Output: long-term outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the therapy implications of transtho-racic echocardiography in acute ischemic stroke patients?. ### Response: long-term outcomes.


Instruction: What is the doi: 10.1161/01.STR.0000170636.08554.49 539?

Output: Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1161/01.STR.0000170636.08554.49 539?. ### Response: Stroke.


Instruction: Who is Vitebskiy S, Fox K, Hoit BD?

Output: 37:859–864. doi: 10.1161/01.STR.0000202592.87021.b7 538. Abreu TT, Mateus S, Correia J. Therapy implications of transtho-racic echocardiography in acute ischemic stroke patients. Stroke. 2005;36:1565–1566. doi: 10.1161/01.STR.0000170636.08554.49 539

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Vitebskiy S, Fox K, Hoit BD?. ### Response: 37:859–864. doi: 10.1161/01.STR.0000202592.87021.b7 538. Abreu TT, Mateus S, Correia J. Therapy implications of transtho-racic echocardiography in acute ischemic stroke patients. Stroke. 2005;36:1565–1566. doi: 10.1161/01.STR.0000170636.08554.49 539.


Instruction: What is apixaban pharmacoki-netics at steady state in in hemodialysis patients?

Output: S4.1.1-56

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is apixaban pharmacoki-netics at steady state in in hemodialysis patients?. ### Response: S4.1.1-56.


Instruction: What is Reed D, Palkimas S, Hockman R, et al. compared to warfarin in dialysis patients.

Output: Safety and effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Reed D, Palkimas S, Hockman R, et al. compared to warfarin in dialysis patients.. ### Response: Safety and effectiveness.


Instruction: How many nongender-related CHA2DS2-VASc risk factors should atrial fibrillation patients be anticoagulated?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many nongender-related CHA2DS2-VASc risk factors should atrial fibrillation patients be anticoagulated?. ### Response: 1.


Instruction: What is the risk factor for atrial fibrosis?

Output: CHA2DS2-VASc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk factor for atrial fibrosis?. ### Response: CHA2DS2-VASc.


Instruction: How is rivaroxaban evaluated in chronic hemodialy-sis patients?

Output: safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is rivaroxaban evaluated in chronic hemodialy-sis patients?. ### Response: safety.


Instruction: What is rivaroxaban used for in chronic hemodialy-sis?

Output: Pharmacokinetics, pharmacody-namics, and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rivaroxaban used for in chronic hemodialy-sis?. ### Response: Pharmacokinetics, pharmacody-namics, and safety.


Instruction: What is the name of the drug that has been studied in a clinical setting?

Output: rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that has been studied in a clinical setting?. ### Response: rivaroxaban.


Instruction: When was this article published?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 23, 2023.


Instruction: Where can this article be found?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can this article be found?. ### Response: http://ahajournals.org.


Instruction: What are BP Goals?

Output: Lower BP Goals for the Prevention  of Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are BP Goals?. ### Response: Lower BP Goals for the Prevention  of Stroke.


Instruction: What are Epidemiology and Coronary Physiology......................................................13823.1.1?

Output: BP Goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Epidemiology and Coronary Physiology......................................................13823.1.1?. ### Response: BP Goals.


Instruction: Which of the following is an example of a Coronary Perfusion and Autoregulation?

Output: the J-curve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which of the following is an example of a Coronary Perfusion and Autoregulation?. ### Response: the J-curve.


Instruction: 13833.2.1. Lower BP With a Surrogate Outcome?

Output: Clinical Studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 13833.2.1. Lower BP With a Surrogate Outcome?. ### Response: Clinical Studies.


Instruction: Observational Studies and Clinical Trials.

Output: 13833.2.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Observational Studies and Clinical Trials.. ### Response: 13833.2.3.


Instruction: 13843.2.4. Lower BP Goals and Diabetes Mellitus?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 13843.2.4. Lower BP Goals and Diabetes Mellitus?. ### Response: ...


Instruction: What is one of the goals for the Prevention of Stroke?

Output: Lower BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the goals for the Prevention of Stroke?. ### Response: Lower BP.


Instruction: 13853.2.6. The Elderly........................ 13953.2.7. Conclusions....................... 13853.3. Recommendations......................... 13864.1. Pharmacological Therapy.................. 13864.1.1.

Output: The Elderly ........................ 13853.2.7.  Conclusions ....................... 13853.3.  Recommendations ........................ 13864.  Management of Hypertension in Patients  With CAD and Stable Angina ................... 13864.1.  Pharmacological Therapy .................. 13864.1.1.  β-Blockers ........................ 13864.1.2.  Calcium Channel Blockers ............ 13864.1.3.  ACE Inhibitors ..................... 13874.1.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 13853.2.6. The Elderly........................ 13953.2.7. Conclusions....................... 13853.3. Recommendations......................... 13864.1. Pharmacological Therapy.................. 13864.1.1.. ### Response: The Elderly ........................ 13853.2.7.  Conclusions ....................... 13853.3.  Recommendations ........................ 13864.  Management of Hypertension in Patients  With CAD and Stable Angina ................... 13864.1.  Pharmacological Therapy .................. 13864.1.1.  β-Blockers ........................ 13864.1.2.  Calcium Channel Blockers ............ 13864.1.3.  ACE Inhibitors ..................... 13874.1..


Instruction: What is the name of the drug used to treat angina?

Output: Angiotensin Receptor Blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat angina?. ### Response: Angiotensin Receptor Blockers.


Instruction: What is another name for ACE Inhibitors?

Output: Calcium Channel Blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for ACE Inhibitors?. ### Response: Calcium Channel Blockers.


Instruction: How is angina treated?

Output: Pharmacological Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is angina treated?. ### Response: Pharmacological Therapy.


Instruction: Which drug is used for angina treatment?

Output: Angiotensin Receptor Blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug is used for angina treatment?. ### Response: Angiotensin Receptor Blockers.


Instruction: What are the recommendations for BP management in patients with ACS?

Output: General Principles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for BP management in patients with ACS?. ### Response: General Principles.


Instruction: What is the Prevalence and Impact on Prognosis of Hypertension?

Output: 13885.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Prevalence and Impact on Prognosis of Hypertension?. ### Response: 13885.2.


Instruction: How are general principles of BP Management in the Patient With ACS addressed?

Output: Prevalence and Impact on Prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are general principles of BP Management in the Patient With ACS addressed?. ### Response: Prevalence and Impact on Prognosis.


Instruction: What is the name of the specific antihypertensive agents in ACS?

Output: 13895.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the specific antihypertensive agents in ACS?. ### Response: 13895.3.


Instruction: Nitroglycerin is what type of blocker?

Output: β-Blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nitroglycerin is what type of blocker?. ### Response: β-Blockers.


Instruction: What is a blocker of calcium channel?

Output: β-Blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a blocker of calcium channel?. ### Response: β-Blockers.


Instruction: What is 13905.3.4?

Output: Calcium Channel Blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 13905.3.4?. ### Response: Calcium Channel Blockers.


Instruction: What are 13915.3.6?

Output: Angiotensin Receptor Blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are 13915.3.6?. ### Response: Angiotensin Receptor Blockers.


Instruction: Diuretics are what?

Output: Pharmacological Therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diuretics are what?. ### Response: Pharmacological Therapies.


Instruction: Anticoagulation in patients with uncontrolled hypertension?

Output: Safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anticoagulation in patients with uncontrolled hypertension?. ### Response: Safety.


Instruction: 13915.5. Conclusions........................................ 13915.6. Recommendations......................................13926. Management of Hypertension in HF of Ischemic Origin.............................. 13926.1. Hypertension and HF Pathophysiology...................... 13936.4.

Output: Safety of Anticoagulation in Patients  With Uncontrolled Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 13915.5. Conclusions........................................ 13915.6. Recommendations......................................13926. Management of Hypertension in HF of Ischemic Origin.............................. 13926.1. Hypertension and HF Pathophysiology...................... 13936.4.. ### Response: Safety of Anticoagulation in Patients  With Uncontrolled Hypertension.


Instruction: What is 13936.4?

Output: Hypertension and HF Pathophysiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 13936.4?. ### Response: Hypertension and HF Pathophysiology.


Instruction: What is 13936.7.1?

Output: Pharmacological Therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 13936.7.1?. ### Response: Pharmacological Therapies.


Instruction: Diuretics are what type of therapy?

Output: Pharmacological

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diuretics are what type of therapy?. ### Response: Pharmacological.


Instruction: 13946.7.5. Nitrates and Hydralazine............ 13956.7.6. Aldosterone Receptor Antagonists.............................................................

Output: 1395

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 13946.7.5. Nitrates and Hydralazine............ 13956.7.6. Aldosterone Receptor Antagonists.............................................................. ### Response: 1395.


Instruction: What does NKF National Kidney FoundationNSAID Nonsteroidal anti-inflammatory drugONTARGET Ongoing Telmisartan Alone and in Combinationwith Ramipril Global Endpoint trialPCR Protein/creatinine ratioPEACE Prevention of Events with Angiotensin-Convert-ing Enzyme Inhibitor TherapyPEEND IT Prevention of Renal and Vascular EndstageDisease Intervention TrialPROGRESS Perindopril Protection Against Recurrent StrokeStudyRAAS Renin-angioten

Output: ﬂammatory drugONTARGET Ongoing Telmisartan Alone and in Combinationwith Ramipril Global Endpoint trialPCR Protein/creatinine ratioPEACE Prevention of Events with Angiotensin-Convert-ing Enzyme Inhibitor Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NKF National Kidney FoundationNSAID Nonsteroidal anti-inflammatory drugONTARGET Ongoing Telmisartan Alone and in Combinationwith Ramipril Global Endpoint trialPCR Protein/creatinine ratioPEACE Prevention of Events with Angiotensin-Convert-ing Enzyme Inhibitor TherapyPEEND IT Prevention of Renal and Vascular EndstageDisease Intervention TrialPROGRESS Perindopril Protection Against Recurrent StrokeStudyRAAS Renin-angioten. ### Response: ﬂammatory drugONTARGET Ongoing Telmisartan Alone and in Combinationwith Ramipril Global Endpoint trialPCR Protein/creatinine ratioPEACE Prevention of Events with Angiotensin-Convert-ing Enzyme Inhibitor Therapy.


Instruction: What is a StrokeStudyRAAS Renin-angiotensin-aldosterone systemRCT Randomized controlled trialREIN-2 Ramipril Efficacy in Nephropathy 2RENAAL Reduction of Endpoints in NIDDM with what Antagonist?

Output: Losartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a StrokeStudyRAAS Renin-angiotensin-aldosterone systemRCT Randomized controlled trialREIN-2 Ramipril Efficacy in Nephropathy 2RENAAL Reduction of Endpoints in NIDDM with what Antagonist?. ### Response: Losartan.


Instruction: What is the name of the Shanghai trial of Nifedipine in the ElderlySyst-Eur Systolic Hypertension in Europe?

Output: STONE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Shanghai trial of Nifedipine in the ElderlySyst-Eur Systolic Hypertension in Europe?. ### Response: STONE.


Instruction: What is another name for Valsartan in the elderly?

Output: Isolated Systolic Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Valsartan in the elderly?. ### Response: Isolated Systolic Hypertension.


Instruction: Who is the World Health Organization?

Output: WHO World Health Organization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the World Health Organization?. ### Response: WHO World Health Organization.


Instruction: What is Valsartan used for in older isolated systolic hypertension?

Output: Randomized Assessment Study inACE Intolerant Subjects with CardiovascularDiseaseUKPDS United Kingdom Prospective Diabetes Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Valsartan used for in older isolated systolic hypertension?. ### Response: Randomized Assessment Study inACE Intolerant Subjects with CardiovascularDiseaseUKPDS United Kingdom Prospective Diabetes Study.


Instruction: What is the name of the World Health Organization?

Output: kidney-international.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the World Health Organization?. ### Response: kidney-international.org.


Instruction: What was the date of the e380 Stroke. 2021:e364–e467?

Output: July

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the date of the e380 Stroke. 2021:e364–e467?. ### Response: July.


Instruction: What did the authors of the 2021 Guideline for the Secondary Prevention of Ischemic Strokereviews identify favorable effects for?

Output: exercise-based interventions with counseling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the authors of the 2021 Guideline for the Secondary Prevention of Ischemic Strokereviews identify favorable effects for?. ### Response: exercise-based interventions with counseling.


Instruction: Exercise interventions initiated within 6 months of stroke/TIA have a larger effect on what?

Output: SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise interventions initiated within 6 months of stroke/TIA have a larger effect on what?. ### Response: SBP.


Instruction: What is the CI for exercise-based programs for stroke secondary prevention?

Output: −9.46 to −1.18]).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CI for exercise-based programs for stroke secondary prevention?. ### Response: −9.46 to −1.18])..


Instruction: What is a TIA?

Output: ambulatory stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a TIA?. ### Response: ambulatory stroke.


Instruction: Many stroke survivors encounter what?

Output: physical and environmental barriers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Many stroke survivors encounter what?. ### Response: physical and environmental barriers.


Instruction: TIA.131–134 Many stroke survivors encounter what barriers to engaging in regular physical activity for health?

Output: physical and environmental

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: TIA.131–134 Many stroke survivors encounter what barriers to engaging in regular physical activity for health?. ### Response: physical and environmental.


Instruction: Neurological weakness, altered perception or balance or impaired cognition may negate their participation in conventional exercises programs?

Output: Many stroke survivors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Neurological weakness, altered perception or balance or impaired cognition may negate their participation in conventional exercises programs?. ### Response: Many stroke survivors.


Instruction: What can help overcome many of these barriers?

Output: Adaptive equip-ment and skilled personnel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can help overcome many of these barriers?. ### Response: Adaptive equip-ment and skilled personnel.


Instruction: How can skilled personnel help overcome many of the barriers to participation?

Output: Adaptive equip-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can skilled personnel help overcome many of the barriers to participation?. ### Response: Adaptive equip-ment.


Instruction: A systematic review of inclusive studies of exercise-based pro-grams in stroke identified that exercise programs are safe and feasible to implement in nonambula-tory individuals but no evidence supports their impact on recurrent stroke?

Output: 135

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A systematic review of inclusive studies of exercise-based pro-grams in stroke identified that exercise programs are safe and feasible to implement in nonambula-tory individuals but no evidence supports their impact on recurrent stroke?. ### Response: 135.


Instruction: What is the impact of aerobic exercise programs on recurrent stroke?

Output: no evidence supports their impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of aerobic exercise programs on recurrent stroke?. ### Response: no evidence supports their impact.


Instruction: Promising pilot studies of what have shown that aerobic exercise is safe and feasible?

Output: aerobic exercise programs inclusive of those with motor disability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Promising pilot studies of what have shown that aerobic exercise is safe and feasible?. ### Response: aerobic exercise programs inclusive of those with motor disability.


Instruction: What can improve cardiovascular fitness and reduce cardiovascular risk profiles?

Output: pre-exercise screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can improve cardiovascular fitness and reduce cardiovascular risk profiles?. ### Response: pre-exercise screening.


Instruction: How much of total accelerometry time were stroke survivors sedentary for?

Output: >78%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of total accelerometry time were stroke survivors sedentary for?. ### Response: >78%.


Instruction: How long after a stroke were community-dwelling, independently mobile indi-viduals identified as being sen-tary for 10.9 h/d and having a low step count?

Output: >6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after a stroke were community-dwelling, independently mobile indi-viduals identified as being sen-tary for 10.9 h/d and having a low step count?. ### Response: >6 months.


Instruction: How long is sedentary?

Output: 10.9 h/d

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is sedentary?. ### Response: 10.9 h/d.


Instruction: How many steps per day are there?

Output: 2411

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many steps per day are there?. ### Response: 2411.


Instruction: What is the mean step count?

Output: 2411 steps per day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mean step count?. ### Response: 2411 steps per day.


Instruction: Why are HRs more pronounced with lower physical activity levels?

Output: cardiovas-cular incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are HRs more pronounced with lower physical activity levels?. ### Response: cardiovas-cular incidence.


Instruction: What trial identified sitting with 3-minute bouts of sitting?

Output: BUST-Stroke trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What trial identified sitting with 3-minute bouts of sitting?. ### Response: BUST-Stroke trial.


Instruction: Sitting with 3-minute bouts of light-intensity activity every 30 minutes decreased SBP by how much?

Output: 3.5 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sitting with 3-minute bouts of light-intensity activity every 30 minutes decreased SBP by how much?. ### Response: 3.5 mm Hg.


Instruction: Sitting without 3-minute interruptions decreased what by 3.5 mm Hg?

Output: SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sitting without 3-minute interruptions decreased what by 3.5 mm Hg?. ### Response: SBP.


Instruction: What did participants not taking antihypertensive medications do?

Output: sitting with 3-minute interruptions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did participants not taking antihypertensive medications do?. ### Response: sitting with 3-minute interruptions.


Instruction: What is the incidence of IE after most procedures?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence of IE after most procedures?. ### Response: low.


Instruction: What can be associated with indiscriminate use of antibiotics?

Output: resistant organisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be associated with indiscriminate use of antibiotics?. ### Response: resistant organisms.


Instruction: What can be associated with the development of resistant organisms, Clostridium difficile colitis, unnecessary expense, and drug toxicity?

Output: Indiscriminate use of anti-biotics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be associated with the development of resistant organisms, Clostridium difficile colitis, unnecessary expense, and drug toxicity?. ### Response: Indiscriminate use of anti-biotics.


Instruction: What is the rate of transient bacteremia during or immediately after endoscopy?

Output: 2% to 5%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rate of transient bacteremia during or immediately after endoscopy?. ### Response: 2% to 5%,.


Instruction: What procedures are associated with higher rates of bacteremia than that for simple endoscopy?

Output: gastrointestinal procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What procedures are associated with higher rates of bacteremia than that for simple endoscopy?. ### Response: gastrointestinal procedures.


Instruction: What percentage of esophageal dilation is associated with high rates of bacteriaemia?

Output: 45%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of esophageal dilation is associated with high rates of bacteriaemia?. ### Response: 45%),.


Instruction: How much of a percentage of endoscopic retrograde cholangiopancreatog-raphy is linked to high levels of bacteria?

Output: 6% to 18%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of a percentage of endoscopic retrograde cholangiopancreatog-raphy is linked to high levels of bacteria?. ### Response: 6% to 18%)..


Instruction: What percentage of IE has been reduced with antibiotic prophy-laxis?

Output: no studies have shown reduced rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of IE has been reduced with antibiotic prophy-laxis?. ### Response: no studies have shown reduced rates.


Instruction: What can surgery, instrumentation, or diagnostic procedures that involve the genitourinary tract cause?

Output: bacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can surgery, instrumentation, or diagnostic procedures that involve the genitourinary tract cause?. ### Response: bacteremia.


Instruction: What is the rate of bacteremia after urinary tract procedures?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rate of bacteremia after urinary tract procedures?. ### Response: low.


Instruction: What is typically provided before elective procedures, including lith-otripsy?

Output: antimicrobial therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is typically provided before elective procedures, including lith-otripsy?. ### Response: antimicrobial therapy.


Instruction: How are the studies that support the recommendations summarized?

Output: Online Data Supplement 2.COR LOE Recommendations1 A1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the studies that support the recommendations summarized?. ### Response: Online Data Supplement 2.COR LOE Recommendations1 A1.


Instruction: Where are the studies that support the recommendations summarized?

Output: Online Data Supplement 2.COR LOE Recommendations1 A1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the studies that support the recommendations summarized?. ### Response: Online Data Supplement 2.COR LOE Recommendations1 A1.


Instruction: What is an effective alternative for patients with AF and native valve heart disease?

Output: NOACs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an effective alternative for patients with AF and native valve heart disease?. ### Response: NOACs.