Instruction: What is the doi: 10.1016/j.emc.2008.08.009?

Output: Emerg Med Clin North Am. 2009;27:27–37, vii–viii. doi: 10.1016/j.emc.2008.08.009. 267

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1016/j.emc.2008.08.009?. ### Response: Emerg Med Clin North Am. 2009;27:27–37, vii–viii. doi: 10.1016/j.emc.2008.08.009. 267.


Instruction: What predicts cerebrovascular and coronary outcomes in the PROGRESS trial?

Output: Prior events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts cerebrovascular and coronary outcomes in the PROGRESS trial?. ### Response: Prior events.


Instruction: When did Stroke. 200637:1497–1502. doi: 10.1161/01.STR.0000221212.36860.c9. 268.

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Stroke. 200637:1497–1502. doi: 10.1161/01.STR.0000221212.36860.c9. 268.. ### Response: 2006.


Instruction: What is the long-term prognosis after recovery from primary intracerebral hemorrhage?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term prognosis after recovery from primary intracerebral hemorrhage?. ### Response: mortality.


Instruction: How many people were hospitalized in 2002?

Output: 269

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were hospitalized in 2002?. ### Response: 269.


Instruction: What was the risk of recurrent stroke?

Output: The risk of recurrent stroke after intracerebral haemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of recurrent stroke?. ### Response: The risk of recurrent stroke after intracerebral haemorrhage.


Instruction: When was the J Neurol Neurosurg Psychiatry 78:836–840?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Neurol Neurosurg Psychiatry 78:836–840?. ### Response: 2007.


Instruction: What is the name of the German Stroke Study Collaboration?

Output: Weimar C, Benemann J, Terborg C, Walter U, Weber R, Diener HC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the German Stroke Study Collaboration?. ### Response: Weimar C, Benemann J, Terborg C, Walter U, Weber R, Diener HC.


Instruction: What type of stroke after lobar and deep intracerebral hemorrhage: a hospital-based cohort study?

Output: Recurrent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stroke after lobar and deep intracerebral hemorrhage: a hospital-based cohort study?. ### Response: Recurrent.


Instruction: What type of hemorrhage is related to cerebral amyloid angiopathy?

Output: lobar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hemorrhage is related to cerebral amyloid angiopathy?. ### Response: lobar.


Instruction: What is a multivariate analyte?

Output: Recurrence and extension of lobar hemorrhage related to cerebral amyloid angiopathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a multivariate analyte?. ### Response: Recurrence and extension of lobar hemorrhage related to cerebral amyloid angiopathy.


Instruction: What type of diabetes has intensive glucose control?

Output: type 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes has intensive glucose control?. ### Response: type 2.


Instruction: What year did N Engl J Med publish 359:1577–1589?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med publish 359:1577–1589?. ### Response: 2008.


Instruction: What does intensive glucose lower-ing do in type 2 diabetes?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does intensive glucose lower-ing do in type 2 diabetes?. ### Response: Effects.


Instruction: What is the N Engl J Med. 2008 358:2545–2559?

Output: Effects of intensive glucose lower -ing in type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2008 358:2545–2559?. ### Response: Effects of intensive glucose lower -ing in type 2 diabetes.


Instruction: What type of blood glucose control is important in patients with diabetes?

Output: intensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of blood glucose control is important in patients with diabetes?. ### Response: intensive.


Instruction: What kind of outcomes are important for diabetic patients?

Output: Intensive blood glucose control and vascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What kind of outcomes are important for diabetic patients?. ### Response: Intensive blood glucose control and vascular.


Instruction: What does intensive blood glucose control and vascular outcomes do in patients with type 2 diabetes?

Output: lower -ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does intensive blood glucose control and vascular outcomes do in patients with type 2 diabetes?. ### Response: lower -ing.


Instruction: What is the name of the journal that published this study?

Output: ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published this study?. ### Response: ahajournals.org.


Instruction: When was this study published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 28, 2023.


Instruction: Who published the 2018 Cholesterol Clinical Practice GuidelinesCirculation. 2019;139:e1082–e1143. DOI: 10.1161/CIR.0000000000000625 June 18/25, 2019 e1083CLINICAL STATEMENTS AND GUIDELINESTABLE OF CONTENTSTop 10 Take-Home Messages to Reduce Risk of Atherosclerotic Cardiovascular Disease Through Cholestrol Management?

Output: Grundy et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2018 Cholesterol Clinical Practice GuidelinesCirculation. 2019;139:e1082–e1143. DOI: 10.1161/CIR.0000000000000625 June 18/25, 2019 e1083CLINICAL STATEMENTS AND GUIDELINESTABLE OF CONTENTSTop 10 Take-Home Messages to Reduce Risk of Atherosclerotic Cardiovascular Disease Through Cholestrol Management?. ### Response: Grundy et al.


Instruction: What is the scope of the guideline?

Output: Class of Recommendation and Level  of Evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the scope of the guideline?. ### Response: Class of Recommendation and Level  of Evidence.


Instruction: What are the abbreviations for High Blood Cholesterol and ASCVD?

Output: e10872

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the abbreviations for High Blood Cholesterol and ASCVD?. ### Response: e10872.


Instruction: Blood Cholesterol and ASCVD............ e10872.1. What is the name of the test that measures LDL-C and Non-HDL-C?

Output: Serum Cholesterol, Lipoproteins, and ASCVD ..e10872.1.1. Cholesterol, Lipoproteins, and  Apolipoprotein B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood Cholesterol and ASCVD............ e10872.1. What is the name of the test that measures LDL-C and Non-HDL-C?. ### Response: Serum Cholesterol, Lipoproteins, and ASCVD ..e10872.1.1. Cholesterol, Lipoproteins, and  Apolipoprotein B.


Instruction: Apolipoprotein B and Lipoprotein (a).................... e10872.1.1.

Output: Serum Cholesterol, Lipoproteins, and ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Apolipoprotein B and Lipoprotein (a).................... e10872.1.1.. ### Response: Serum Cholesterol, Lipoproteins, and ASCVD.


Instruction: What is a measure of Apolipoprotein B and Lipoprotein (a)?

Output: LDL-C and Non–HDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a measure of Apolipoprotein B and Lipoprotein (a)?. ### Response: LDL-C and Non–HDL-C.


Instruction: Monitoring Response of LDL-C to Statin Therapy?

Output: e10903

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Monitoring Response of LDL-C to Statin Therapy?. ### Response: e10903.


Instruction: What are Lifestyle Therapies and Metabolic Syndrome?

Output: Diet Composition, Weight Control,  and Physical Activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Lifestyle Therapies and Metabolic Syndrome?. ### Response: Diet Composition, Weight Control,  and Physical Activity.


Instruction: What is a Metabolic Syndrome?

Output: Lifestyle Therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Metabolic Syndrome?. ### Response: Lifestyle Therapies.


Instruction: What are Lipid-Lowering Drugs?

Output: Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Lipid-Lowering Drugs?. ### Response: Therapy.


Instruction: Statin Therapy is an example of what?

Output: Lipid-Lowering Drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Statin Therapy is an example of what?. ### Response: Lipid-Lowering Drugs.


Instruction: Nonstatin Add-on Drugs to Statin Therapies are examples of what kind of therapy?

Output: Statin Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nonstatin Add-on Drugs to Statin Therapies are examples of what kind of therapy?. ### Response: Statin Therapy.


Instruction: How many mg/dL does a person with diabetes have?

Output: ≥190

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg/dL does a person with diabetes have?. ### Response: ≥190.


Instruction: How many mmol/l is diabetes in adults?

Output: 4.9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mmol/l is diabetes in adults?. ### Response: 4.9.


Instruction: What is the primary prevention for adults with diabetes?

Output: Evaluation and Risk Assessment ..... e10994.4.2. Primary Prevention Adults 40 to  75 Years of Age With LDL-C Levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention for adults with diabetes?. ### Response: Evaluation and Risk Assessment ..... e10994.4.2. Primary Prevention Adults 40 to  75 Years of Age With LDL-C Levels.


Instruction: What is the range of mg/dL?

Output: ≥190

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the range of mg/dL?. ### Response: ≥190.


Instruction: What is a primary prevention in other age groups?

Output: LDL-C Levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a primary prevention in other age groups?. ### Response: LDL-C Levels.


Instruction: How is hypertriglyceridemia treated?

Output: Implementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is hypertriglyceridemia treated?. ### Response: Implementation.


Instruction: What is a side effect of PCSK9?

Output: Economic Value Considerations:  PCSK9 Inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a side effect of PCSK9?. ### Response: Economic Value Considerations:  PCSK9 Inhibitors.


Instruction: What is an economic value consideration?

Output: PCSK9 Inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an economic value consideration?. ### Response: PCSK9 Inhibitors.


Instruction: e11228.1. Randomized Controlled Trials.............................................................

Output: e1122

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: e11228.1. Randomized Controlled Trials.............................................................. ### Response: e1122.


Instruction: What are Jordanian acute coronary syndrome patients’ learn-ing needs?

Output: implications for cardiac rehabilitation and second-ary prevention programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are Jordanian acute coronary syndrome patients’ learn-ing needs?. ### Response: implications for cardiac rehabilitation and second-ary prevention programs.


Instruction: What are implications for cardiac rehabilitation and secondary prevention programs?

Output: Jordanian acute coronary syndrome patients’ learn-ing needs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are implications for cardiac rehabilitation and secondary prevention programs?. ### Response: Jordanian acute coronary syndrome patients’ learn-ing needs.


Instruction: When was Nurs Health Sci published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Nurs Health Sci published?. ### Response: 2011.


Instruction: What is the name of the program that treats cardiac reha-bilitation?

Output: Cardiac Home Education and Support Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the program that treats cardiac reha-bilitation?. ### Response: Cardiac Home Education and Support Trial.


Instruction: How many people were enrolled in the 2008 J Cardiopulm Rehabil Prev.28?

Output: 187–188

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the 2008 J Cardiopulm Rehabil Prev.28?. ### Response: 187–188.


Instruction: What was the CHANGE intervention used for?

Output: enhance long-term exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the CHANGE intervention used for?. ### Response: enhance long-term exercise.


Instruction: What does CHEST stand for?

Output: Cardiac Home Education and Support Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CHEST stand for?. ### Response: Cardiac Home Education and Support Trial.


Instruction: What is the name of the pilot study that evaluated CHEST?

Output: Cardiac Home Education and Support Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pilot study that evaluated CHEST?. ### Response: Cardiac Home Education and Support Trial.


Instruction: How does Hartcoach work?

Output: a life style intervention provided by telephone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Hartcoach work?. ### Response: a life style intervention provided by telephone.


Instruction: What type of intervention was provided by telephone on the reduction of coronary risk factors?

Output: life style

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention was provided by telephone on the reduction of coronary risk factors?. ### Response: life style.


Instruction: What is the name of the randomised trial?

Output: Hartcoach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial?. ### Response: Hartcoach.


Instruction: When was the trial downloaded?

Output: April 26, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the trial downloaded?. ### Response: April 26, 2023.


Instruction: What is a lifetime risk for sudden cardiac death in the community?

Output: S10.6-10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a lifetime risk for sudden cardiac death in the community?. ### Response: S10.6-10.


Instruction: What is the J Am Heart Assoc. 2016:5:e002398?

Output: Lifetime risk for sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Heart Assoc. 2016:5:e002398?. ### Response: Lifetime risk for sudden cardiac death.


Instruction: In what year did Circulation. 2001:104:2699–703?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Circulation. 2001:104:2699–703?. ### Response: 2001.


Instruction: What is the survival advantage from ventricular fibrillation and pulseless electrical activity in women compared to men?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the survival advantage from ventricular fibrillation and pulseless electrical activity in women compared to men?. ### Response: age.


Instruction: What was the Oregon Sudden Unexpected Death Study?

Output: Ore-SUDS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Oregon Sudden Unexpected Death Study?. ### Response: Ore-SUDS.


Instruction: When was the J Interv Card Electrophysiol.34:219–25?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Interv Card Electrophysiol.34:219–25?. ### Response: 2012.


Instruction: What does survival after out-of-hospital cardiac arrest in relation to sex?

Output: age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does survival after out-of-hospital cardiac arrest in relation to sex?. ### Response: age.


Instruction: What is a nationwide registry-based study?

Output: Survival after out-of-hospital cardiac arrest in relation to sex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a nationwide registry-based study?. ### Response: Survival after out-of-hospital cardiac arrest in relation to sex.


Instruction: What is the gender of cardiac arrest patients in Pan-Asian out-of-hospital patients?

Output: women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the gender of cardiac arrest patients in Pan-Asian out-of-hospital patients?. ### Response: women.


Instruction: What are the resuscitation out-comes of reproductive-age females who experienced cardiac arrest?

Output: lower prevalence of structural heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the resuscitation out-comes of reproductive-age females who experienced cardiac arrest?. ### Response: lower prevalence of structural heart disease.


Instruction: What did the OPALS study show about the survival of men and women from cardiac arrest?

Output: Differential survival for men and women from out-of-hospital cardiac arrest varies by age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the OPALS study show about the survival of men and women from cardiac arrest?. ### Response: Differential survival for men and women from out-of-hospital cardiac arrest varies by age.


Instruction: What did Albert CM, McGovern, and Stiell IG do?

Output: out-of-hospital cardiac arrest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Albert CM, McGovern, and Stiell IG do?. ### Response: out-of-hospital cardiac arrest.


Instruction: What is the name of the OPALS study?

Output: Oregon Sudden Unexpected Death Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the OPALS study?. ### Response: Oregon Sudden Unexpected Death Study.


Instruction: What is a precursor to sudden cardiac arrest?

Output: structural heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a precursor to sudden cardiac arrest?. ### Response: structural heart disease.


Instruction: Who has a lower prevalence of structural heart disease?

Output: Women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has a lower prevalence of structural heart disease?. ### Response: Women.


Instruction: What is the name of the Oregon Sudden Unexpected Death Study?

Output: Ore-SUDS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Oregon Sudden Unexpected Death Study?. ### Response: Ore-SUDS.


Instruction: When did the Ore-SUDS take place?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Ore-SUDS take place?. ### Response: 2009.


Instruction: What gender was used in cardiac arrest patients?

Output: women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What gender was used in cardiac arrest patients?. ### Response: women.


Instruction: What is a risk factor for torsades de pointes associated with cardiovascular drugs?

Output: Female gender

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for torsades de pointes associated with cardiovascular drugs?. ### Response: Female gender.


Instruction: What is the cause of sudden death in France by specific sports and sex?

Output: Incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of sudden death in France by specific sports and sex?. ### Response: Incidence.


Instruction: When was JAMA 270:2590-7. S10.6-23. Higgins AY, Waks JWJosephson ME, Influence of gender on the tolerability, safety, and efficacy of quinidine used for treatment of supraventricular and ventricular arrhythmias.

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was JAMA 270:2590-7. S10.6-23. Higgins AY, Waks JWJosephson ME, Influence of gender on the tolerability, safety, and efficacy of quinidine used for treatment of supraventricular and ventricular arrhythmias.. ### Response: 1993.


Instruction: What is the gender and age difference in candi-dates for radiofrequency catheter ablation of idiopathic ventricular arrhythmias?

Output: Differential survival for men and women from out-of-hospital cardiac arrest varies by age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the gender and age difference in candi-dates for radiofrequency catheter ablation of idiopathic ventricular arrhythmias?. ### Response: Differential survival for men and women from out-of-hospital cardiac arrest varies by age.


Instruction: What is Faboxin-specific?

Output: sports and sex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Faboxin-specific?. ### Response: sports and sex.


Instruction: How many cases of life-threatening digitalis intoxication were treated with digoxin?

Output: 150

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of life-threatening digitalis intoxication were treated with digoxin?. ### Response: 150.


Instruction: What should be considered in every patient?

Output: anatomic and physiological variables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered in every patient?. ### Response: anatomic and physiological variables.


Instruction: What should a patient be classified based on in Tables 3 and 4?

Output: the “highest” relevant anatomic or physiological feature

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient be classified based on in Tables 3 and 4?. ### Response: the “highest” relevant anatomic or physiological feature.


Instruction: What should a patient be classified based on?

Output: the “highest” relevant anatomic or physiological feature

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a patient be classified based on?. ### Response: the “highest” relevant anatomic or physiological feature.


Instruction: A normotensive patient with repaired CoA, normal exercise capacity, and normal end-organ function would be classified as what?

Output: ACHD AP classifi-cation IIA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A normotensive patient with repaired CoA, normal exercise capacity, and normal end-organ function would be classified as what?. ### Response: ACHD AP classifi-cation IIA.


Instruction: What is an otherwise similar patient with as-cending aortic diameter of 4.0 cm?

Output: ACHD AP classification IIB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an otherwise similar patient with as-cending aortic diameter of 4.0 cm?. ### Response: ACHD AP classification IIB.


Instruction: What would be the ACHD AP classification IIB with as-cending aortic diameter of 4.0 cm?

Output: patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be the ACHD AP classification IIB with as-cending aortic diameter of 4.0 cm?. ### Response: patient.


Instruction: What classification would be IIC if moderate stenosis were also present?

Output: ACHD AP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What classification would be IIC if moderate stenosis were also present?. ### Response: ACHD AP.


Instruction: Patients with ACHD may have what?

Output: baseline exercise limitations, cyanosis, end-organ dysfunction, or other clinically important comorbidities related to their CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with ACHD may have what?. ### Response: baseline exercise limitations, cyanosis, end-organ dysfunction, or other clinically important comorbidities related to their CHD.


Instruction: What are the clinically important comorbidities related to their CHD?

Output: baseline exercise limitations, cyanosis, end-organ dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinically important comorbidities related to their CHD?. ### Response: baseline exercise limitations, cyanosis, end-organ dysfunction.


Instruction: What are they at risk of?

Output: HF, arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are they at risk of?. ### Response: HF, arrhythmias.


Instruction: Dyspnea, chest pain, and exercise intolerance are examples of what?

Output: cardiac symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dyspnea, chest pain, and exercise intolerance are examples of what?. ### Response: cardiac symptoms.


Instruction: What may be present in patients with ACHD?

Output: baseline exercise limitations, cyanosis, end-organ dysfunction, or other clinically important comorbidities related to their CHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be present in patients with ACHD?. ### Response: baseline exercise limitations, cyanosis, end-organ dysfunction, or other clinically important comorbidities related to their CHD.


Instruction: There are growing data regarding the prognostic implications of what?

Output: patients with ACHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are growing data regarding the prognostic implications of what?. ### Response: patients with ACHD.


Instruction: What is not the abun-dance of data available for patients with acquired heart disease?

Output: prognostic implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not the abun-dance of data available for patients with acquired heart disease?. ### Response: prognostic implications.


Instruction: Why were the data in Table 3 selected?

Output: data exist sug-gesting their importance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were the data in Table 3 selected?. ### Response: data exist sug-gesting their importance.


Instruction: What does QoL stand for?

Output: quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does QoL stand for?. ### Response: quality of life.


Instruction: As new data become availa-ble, what will happen to the relative weights attributable to the components of the ACHD AP classification?

Output: changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: As new data become availa-ble, what will happen to the relative weights attributable to the components of the ACHD AP classification?. ### Response: changes.


Instruction: What is similar to the New York Heart Association classification of functional status?

Output: ACHD AP classification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is similar to the New York Heart Association classification of functional status?. ### Response: ACHD AP classification.


Instruction: What may patients move from one ACHD AP classification to another over time?

Output: functional status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients move from one ACHD AP classification to another over time?. ### Response: functional status.


Instruction: What happens if clinical status worsens?

Output: the classification will change to a higher severity group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What happens if clinical status worsens?. ### Response: the classification will change to a higher severity group.


Instruction: What can result in a classification change to a lower severity group?

Output: improvement in status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can result in a classification change to a lower severity group?. ### Response: improvement in status.


Instruction: What is the AHA HF A to D classification?

Output: S2.3-17

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHA HF A to D classification?. ### Response: S2.3-17.


Instruction: What classification is used throughout this document?

Output: ACHD AP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What classification is used throughout this document?. ### Response: ACHD AP.


Instruction: When considering follow-up visits and need for testing, what is used?

Output: ACHD AP classification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When considering follow-up visits and need for testing, what is used?. ### Response: ACHD AP classification.


Instruction: What changes in physiology can cause the ACHD AP classification to worsen?

Output: development of arrhyth-mias, HF, end-organ disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What changes in physiology can cause the ACHD AP classification to worsen?. ### Response: development of arrhyth-mias, HF, end-organ disease.


Instruction: What should be considered when considering follow-up visits and need for testing?

Output: ACHD AP classification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered when considering follow-up visits and need for testing?. ### Response: ACHD AP classification.


Instruction: What may not adequately discrimi-nate physiological changes that alter severity over time?

Output: anatomic disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not adequately discrimi-nate physiological changes that alter severity over time?. ### Response: anatomic disease.


Instruction: What has been found in several studies of patients with established SIHD?

Output: tality risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been found in several studies of patients with established SIHD?. ### Response: tality risk.


Instruction: What has the incidence of ad-verse events during longitudinal follow-up of SIHD decreased?

Output: The incidence of ad-verse events during longitudinal follow-up of SIHD hasdeclined

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has the incidence of ad-verse events during longitudinal follow-up of SIHD decreased?. ### Response: The incidence of ad-verse events during longitudinal follow-up of SIHD hasdeclined.


Instruction: What is one approach to identifying candidates for follow-up testing?

Output: applyprognostic scores

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one approach to identifying candidates for follow-up testing?. ### Response: applyprognostic scores.


Instruction: What are patients with SIHD who areat high risk of?

Output: MACE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with SIHD who areat high risk of?. ### Response: MACE.


Instruction: What could provide clues for identifying candi-dates and appropriate intervals for follow-up testing?

Output: clinical characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could provide clues for identifying candi-dates and appropriate intervals for follow-up testing?. ### Response: clinical characteristics.


Instruction: What study group comprised 682 patients with stable angina and positive exercise ECG tests?

Output: TIBET (Total Ischemic Burden European Trial)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study group comprised 682 patients with stable angina and positive exercise ECG tests?. ### Response: TIBET (Total Ischemic Burden European Trial).


Instruction: How was adverse outcome predicted in theTIBET study group?

Output: by time toischemia during exercise, prior infarction or prior CABG,ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was adverse outcome predicted in theTIBET study group?. ### Response: by time toischemia during exercise, prior infarction or prior CABG,ECG.


Instruction: What was the strongest predictor of risk during follow-up ofpatients with SIHD in other studies?

Output: Easily available clinical characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the strongest predictor of risk during follow-up ofpatients with SIHD in other studies?. ### Response: Easily available clinical characteristics.


Instruction: What did the Euro Heart Surveyfound?

Output: a score based on the cumulative presence ofcomorbidity, diabetes mellitus, severity of angina, onset ofrecurrent symptoms /H110216 months previously, abnormal ven-tricular function, and resting ECG repolarization abnormali-ties was associated with an increase in the 1-year risk of deathor nonfatal infarction that ranged nearly 100-fold (from 0.5%to 47%) among /H110223000 outpatients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Euro Heart Surveyfound?. ### Response: a score based on the cumulative presence ofcomorbidity, diabetes mellitus, severity of angina, onset ofrecurrent symptoms /H110216 months previously, abnormal ven-tricular function, and resting ECG repolarization abnormali-ties was associated with an increase in the 1-year risk of deathor nonfatal infarction that ranged nearly 100-fold (from 0.5%to 47%) among /H110223000 outpatients.


Instruction: What did the Euro Heart Survey find associated with an increase in the 1-year risk of death or nonfatal infarction?

Output: a score based on the cumulative presence ofcomorbidity, diabetes mellitus, severity of angina, onset ofrecurrent symptoms /H110216 months previously, abnormal ven-tricular function, and resting ECG repolarization abnormali-ties

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Euro Heart Survey find associated with an increase in the 1-year risk of death or nonfatal infarction?. ### Response: a score based on the cumulative presence ofcomorbidity, diabetes mellitus, severity of angina, onset ofrecurrent symptoms /H110216 months previously, abnormal ven-tricular function, and resting ECG repolarization abnormali-ties.


Instruction: What was the 1-year risk of death or nonfatal infarction among outpatients of /H110223000?

Output: 47%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 1-year risk of death or nonfatal infarction among outpatients of /H110223000?. ### Response: 47%).


Instruction: The ACTION trial derived aclinical risk score that separated 5-year risks of death, MI, or stroke from 4% to what percentage?

Output: 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ACTION trial derived aclinical risk score that separated 5-year risks of death, MI, or stroke from 4% to what percentage?. ### Response: 35%.


Instruction: What percentage of patients with stable angina had angina?

Output: 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with stable angina had angina?. ### Response: 35%.


Instruction: What were the most common clinical variables?

Output: age,LVEF, smoking, white blood cell count, presence of diabetesmellitus, casual

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the most common clinical variables?. ### Response: age,LVEF, smoking, white blood cell count, presence of diabetesmellitus, casual.


Instruction: How did the variables change in importance?

Output: decreasing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the variables change in importance?. ### Response: decreasing.


Instruction: How long has it been since the last meal?

Output: H110216 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has it been since the last meal?. ### Response: H110216 months.


Instruction: What is the QT interval on the resting ECG?

Output: inine, priorstroke, frequent angina, findings at coronary angiography,lipid-lowering treatment, QT interval on the resting ECG,systolic hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the QT interval on the resting ECG?. ### Response: inine, priorstroke, frequent angina, findings at coronary angiography,lipid-lowering treatment, QT interval on the resting ECG,systolic hypertension.


Instruction: Why are the results of these studies different?

Output: Because the populations enrolled inthese studies varied and the results have not been indepen-dently validated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why are the results of these studies different?. ### Response: Because the populations enrolled inthese studies varied and the results have not been indepen-dently validated.


Instruction: What is required to establish appropriate follow-up evaluation strategies and to establish efficient timeintervals for evaluation in stable patients?

Output: additional prospective studies of patientswith established SIHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required to establish appropriate follow-up evaluation strategies and to establish efficient timeintervals for evaluation in stable patients?. ### Response: additional prospective studies of patientswith established SIHD.


Instruction: What are standard risk assessment tools developed from?

Output: clinical and laboratory evaluation of ambulatory populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are standard risk assessment tools developed from?. ### Response: clinical and laboratory evaluation of ambulatory populations.


Instruction: How long has CHEST been developing and publishing guidelines for the treatment of DVT and PE?

Output: more than 30 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has CHEST been developing and publishing guidelines for the treatment of DVT and PE?. ### Response: more than 30 years.


Instruction: When did CHEST publish the last (9th) edition of these guidelines?

Output: February 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did CHEST publish the last (9th) edition of these guidelines?. ### Response: February 2012.


Instruction: What does NOAC stand for?

Output: non-vitamin Koral anticoagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NOAC stand for?. ### Response: non-vitamin Koral anticoagulants.


Instruction: What is the name of the anticoagulant used to treat VTE?

Output: non-vitamin Koral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the anticoagulant used to treat VTE?. ### Response: non-vitamin Koral.


Instruction: How many topics were included in AT9?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many topics were included in AT9?. ### Response: 12.


Instruction: Who is the target user of the guideline?

Output: clinicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the target user of the guideline?. ### Response: clinicians.


Instruction: What committee appointed theeditor for the guide line?

Output: Guidelines Oversight Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What committee appointed theeditor for the guide line?. ### Response: Guidelines Oversight Committee.


Instruction: How many new topics were provided for in the article?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many new topics were provided for in the article?. ### Response: 3.


Instruction: Who appointed theeditor for the guideline update?

Output: The Guidelines Oversight Committee (GOC) at CHEST

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who appointed theeditor for the guideline update?. ### Response: The Guidelines Oversight Committee (GOC) at CHEST.


Instruction: Who nominated the projectexecutive committee, the chair, and the remaining panelists?

Output: the editor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who nominated the projectexecutive committee, the chair, and the remaining panelists?. ### Response: the editor.


Instruction: What did the GOC approve after review of their quali fications and conflict of interest (COI)disclosures?

Output: all panelists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the GOC approve after review of their quali fications and conflict of interest (COI)disclosures?. ### Response: all panelists.


Instruction: How many panelists participated in COIdisclosures?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many panelists participated in COIdisclosures?. ### Response: 15.


Instruction: Who were required to disclose financial and intellectual con flicts of interest by topic?

Output: panelists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were required to disclose financial and intellectual con flicts of interest by topic?. ### Response: panelists.


Instruction: What was required to abstain from voting on related topic areas?

Output: Panelists with primary COIs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was required to abstain from voting on related topic areas?. ### Response: Panelists with primary COIs.


Instruction: What could participate in discussions provided they avoided strong advocacy?

Output: Panelists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could participate in discussions provided they avoided strong advocacy?. ### Response: Panelists.


Instruction: How many topic areas were listed from AT9?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many topic areas were listed from AT9?. ### Response: 12.


Instruction: How many topic areas did the panel add to the AT9 update?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many topic areas did the panel add to the AT9 update?. ### Response: 12.


Instruction: How many topics did the full panel vote on?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many topics did the full panel vote on?. ### Response: 15.


Instruction: What was the total number of topics the panel selected?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the total number of topics the panel selected?. ### Response: 15.


Instruction: How many topics were on the finallist?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many topics were on the finallist?. ### Response: 15.


Instruction: How many new topics were selected from AT9?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many new topics were selected from AT9?. ### Response: 3.


Instruction: What did the panel develop for each topic?

Output: standardizedquest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the panel develop for each topic?. ### Response: standardizedquest.


Instruction: What was used to search for evidence for each question?

Output: Systematic SearchSystematic methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to search for evidence for each question?. ### Response: Systematic SearchSystematic methods.


Instruction: Where did we search for original studies?

Output: MEDLINEvia PubMed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did we search for original studies?. ### Response: MEDLINEvia PubMed.


Instruction: What was searched for for systematic reviews?

Output: Cochrane Library

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was searched for for systematic reviews?. ### Response: Cochrane Library.


Instruction: When did we search theliterature for new topics?

Output: 1946 (Medline inception) to July 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did we search theliterature for new topics?. ### Response: 1946 (Medline inception) to July 2014.


Instruction: When was Medline inception?

Output: 1946

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Medline inception?. ### Response: 1946.


Instruction: What language were all searches limited to?

Output: English

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What language were all searches limited to?. ### Response: English.


Instruction: What is one of the leading causes of hospital-acquired AKI?

Output: Contrast-induced AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the leading causes of hospital-acquired AKI?. ### Response: Contrast-induced AKI.


Instruction: What are some major risk factors for contrast-induced AKI.

Output: advanced age, CKD,congestive heart failure, diabetes, and the volume of contrastadministered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some major risk factors for contrast-induced AKI.. ### Response: advanced age, CKD,congestive heart failure, diabetes, and the volume of contrastadministered.


Instruction: What is available to predict therisk of contrast nephropathy using these risk factors and additional variables?

Output: A risk-scoring system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is available to predict therisk of contrast nephropathy using these risk factors and additional variables?. ### Response: A risk-scoring system.


Instruction: What are the only strategies to reduce the risk of contrast-induced AKI?

Output: hydra-tion and minimizing the amount of contrast media

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the only strategies to reduce the risk of contrast-induced AKI?. ### Response: hydra-tion and minimizing the amount of contrast media.


Instruction: What are measures that were believed to reducetherisk of contrast nephropathy found to be?

Output: neutral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are measures that were believed to reducetherisk of contrast nephropathy found to be?. ### Response: neutral.


Instruction: What has been found to be neutral, to have deleterious effects, or to be characterized by heteroge-neous and conflicting data?

Output: thansaline hydration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been found to be neutral, to have deleterious effects, or to be characterized by heteroge-neous and conflicting data?. ### Response: thansaline hydration.


Instruction: Isotonic saline is preferable to what?

Output: half isotonicsaline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Isotonic saline is preferable to what?. ### Response: half isotonicsaline.


Instruction: Intravenous hydration is preferred to oral hydra-tion?

Output: IV) hydration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Intravenous hydration is preferred to oral hydra-tion?. ### Response: IV) hydration.


Instruction: What is preferable to oral hydra-tion?

Output: intravenous (IV) hydration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preferable to oral hydra-tion?. ### Response: intravenous (IV) hydration.


Instruction: What is preferred to a bolus administration of saline immediately before or during contrast media exposure?

Output: hydration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preferred to a bolus administration of saline immediately before or during contrast media exposure?. ### Response: hydration.


Instruction: What isotonic saline plus mannitol or furosemide?

Output: administra-tion of isotonic saline alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What isotonic saline plus mannitol or furosemide?. ### Response: administra-tion of isotonic saline alone.


Instruction: What is a reasonable hydration regimen for 3 to 12 hours before the procedure and continuing for 6 to 24 hours after the procedure?

Output: isotonic crystalloid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable hydration regimen for 3 to 12 hours before the procedure and continuing for 6 to 24 hours after the procedure?. ### Response: isotonic crystalloid.


Instruction: Which two substances have produced conflicting results?

Output: N-acetyl-L-cysteine and sodium bicarbon-ate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which two substances have produced conflicting results?. ### Response: N-acetyl-L-cysteine and sodium bicarbon-ate.


Instruction: What has produced conflicting results in studies of N-acetyl-L-cysteine and sodium bicarbon-ate?

Output: Prior studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has produced conflicting results in studies of N-acetyl-L-cysteine and sodium bicarbon-ate?. ### Response: Prior studies.


Instruction: What did some early studies suggest?

Output: benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did some early studies suggest?. ### Response: benefit.


Instruction: There are potential issues of what in several analyses?

Output: publication bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are potential issues of what in several analyses?. ### Response: publication bias.


Instruction: What was the name of the largest randomized study onN-acetyl-L-cysteine and contrast nephropathy in patientsundergoing angiographic procedures?

Output: ACT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the largest randomized study onN-acetyl-L-cysteine and contrast nephropathy in patientsundergoing angiographic procedures?. ### Response: ACT.


Instruction: What did the ACT (Acetylcysteinefor Contrast-Induced Nephropathy Trial) demonstrate in primary or secondary endpoints?

Output: nobenefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ACT (Acetylcysteinefor Contrast-Induced Nephropathy Trial) demonstrate in primary or secondary endpoints?. ### Response: nobenefit.


Instruction: N-acetyl-L-cysteine does not prevent what in patients undergoing angiographic procedures?

Output: contrast-induced AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: N-acetyl-L-cysteine does not prevent what in patients undergoing angiographic procedures?. ### Response: contrast-induced AKI.


Instruction: The correlation between the volume of contrast media and the risk of contrast-induced AKI has been documented in what studies?

Output: several studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The correlation between the volume of contrast media and the risk of contrast-induced AKI has been documented in what studies?. ### Response: several studies.


Instruction: What has been documented in several studies?

Output: The correlation between the volume of contrast media andthe risk of contrast-induced AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been documented in several studies?. ### Response: The correlation between the volume of contrast media andthe risk of contrast-induced AKI.


Instruction: What is important to prevent contrast-induced AKI inpatientsundergoing angiography?

Output: minimization of contrast mediavolume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to prevent contrast-induced AKI inpatientsundergoing angiography?. ### Response: minimization of contrast mediavolume.


Instruction: The volume of contrast already administered during diagnostic catheterization is animportant factor when considering what type of PCI?

Output: ad hoc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The volume of contrast already administered during diagnostic catheterization is animportant factor when considering what type of PCI?. ### Response: ad hoc.


Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e91 S8.1.2-2?

Output: Whelton et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e91 S8.1.2-2?. ### Response: Whelton et al.


Instruction: Ettehad D, Emdin CA, Kiran A, et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis.

Output: Whelton et al  2017 High Blood Pressure Clinical Practice Guideline  e91 S8.1.2-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ettehad D, Emdin CA, Kiran A, et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis.. ### Response: Whelton et al  2017 High Blood Pressure Clinical Practice Guideline  e91 S8.1.2-2.


Instruction: Who collaborated with Blood Pressure Lowering Treatment Trialists' Collaboration?

Output: Sundstrom J, Arima H, Woodward M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who collaborated with Blood Pressure Lowering Treatment Trialists' Collaboration?. ### Response: Sundstrom J, Arima H, Woodward M.


Instruction: Blood pressure-lowering treatment based on cardiovascular risk: a meta-analysis of individual patient data.

Output: Blood Pressure Lowering Treatment Trialists' Collaboration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood pressure-lowering treatment based on cardiovascular risk: a meta-analysis of individual patient data.. ### Response: Blood Pressure Lowering Treatment Trialists' Collaboration.


Instruction: What is the effect of lowering blood pressure on outcome incidence in hypertension?

Output: 2. Effects at differ -ent baseline and achieved blood pressure levels–overview and meta-analyses of randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of lowering blood pressure on outcome incidence in hypertension?. ### Response: 2. Effects at differ -ent baseline and achieved blood pressure levels–overview and meta-analyses of randomized trials.


Instruction: What are the effects at differ -ent baseline and achieved blood pressure levels?

Output: –overview and meta-analyses of randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects at differ -ent baseline and achieved blood pressure levels?. ### Response: –overview and meta-analyses of randomized trials.


Instruction: What is mild hypertension: a systematic review and meta-anal-ysis?

Output: Effects of blood pressure reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is mild hypertension: a systematic review and meta-anal-ysis?. ### Response: Effects of blood pressure reduction.


Instruction: What is a meta-analysis of antihypertensive treatment and secondary prevention of cardiovascular disease events among persons without hypertension?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of antihypertensive treatment and secondary prevention of cardiovascular disease events among persons without hypertension?. ### Response: JAMA.


Instruction: Atkins E, Lv J, et al. Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. 2016;387:435–43.

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atkins E, Lv J, et al. Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. 2016;387:435–43.. ### Response: Lancet.


Instruction: Wright JT Jr, Williamson JD, Whelton PK, and others. A randomized trial of intensive versus standard blood pressure control.

Output: 2015;162:184–91. S8.1.2-6. Thompson AM, Hu T, Eshelbrenner CL, et al. Antihypertensive treatment and secondary prevention of cardiovascular disease events among persons without hypertension: a meta-analysis. JAMA. 2011;305:913–22. S8.1.2-7. Xie X, Atkins E, Lv J, et al. Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. Lancet. 2016;387:435–43. S8.1.2-8. Wright JT Jr, Williamson JD, Whelton PK, et al. A randomized trial of intensive versus standard blood-pressure control. SPRINT Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Wright JT Jr, Williamson JD, Whelton PK, and others. A randomized trial of intensive versus standard blood pressure control.. ### Response: 2015;162:184–91. S8.1.2-6. Thompson AM, Hu T, Eshelbrenner CL, et al. Antihypertensive treatment and secondary prevention of cardiovascular disease events among persons without hypertension: a meta-analysis. JAMA. 2011;305:913–22. S8.1.2-7. Xie X, Atkins E, Lv J, et al. Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. Lancet. 2016;387:435–43. S8.1.2-8. Wright JT Jr, Williamson JD, Whelton PK, et al. A randomized trial of intensive versus standard blood-pressure control. SPRINT Research Group.


Instruction: What is standard blood-pressure control?

Output: intensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is standard blood-pressure control?. ### Response: intensive.


Instruction: What is the N Engl J Med. 2015:373:2103-16?

Output: A randomized trial of intensive versus standard blood-pressure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2015:373:2103-16?. ### Response: A randomized trial of intensive versus standard blood-pressure control.


Instruction: Who is the SPRINT Research Group?

Output: N Engl J Med.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the SPRINT Research Group?. ### Response: N Engl J Med..


Instruction: When did Lewington die?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Lewington die?. ### Response: 2002.


Instruction: What is the age-specific relevance of usual blood pressure to vascular mortality?

Output: a meta-analysis of individual data for one million adults in 61 prospective studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age-specific relevance of usual blood pressure to vascular mortality?. ### Response: a meta-analysis of individual data for one million adults in 61 prospective studies.


Instruction: How many prospective studies were there in 2002?

Output: 61

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many prospective studies were there in 2002?. ### Response: 61.


Instruction: What was the name of the meta-analysis?

Output: Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the meta-analysis?. ### Response: Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.


Instruction: What is the effect of blood pressure lowering on cardiovascular outcomes in different cardiovascu-lar risk groups among participants with type 2 diabetes?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of blood pressure lowering on cardiovascular outcomes in different cardiovascu-lar risk groups among participants with type 2 diabetes?. ### Response: Effects.


Instruction: When did Diabetes Res Clin Pract. 2012:98:83–90?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Diabetes Res Clin Pract. 2012:98:83–90?. ### Response: 2012.


Instruction: What was the impact of absolute cardiovascular outcome?

Output: deci-sion to treat hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the impact of absolute cardiovascular outcome?. ### Response: deci-sion to treat hypertension.


Instruction: How did Montgomery AA, Fahey, and Ben-Shlomo compare?

Output: 2-12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Montgomery AA, Fahey, and Ben-Shlomo compare?. ### Response: 2-12.


Instruction: What is the effect of absolute cardiovascular risk, patient utilities, and costs on the decision to treat hypertension?

Output: Markov decision analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of absolute cardiovascular risk, patient utilities, and costs on the decision to treat hypertension?. ### Response: Markov decision analysis.


Instruction: When did the J Hypertens. 2003:21:1753-9?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Hypertens. 2003:21:1753-9?. ### Response: 2003.


Instruction: What did Kassai B, Boissel J-P, Cucherat M, et al. study?

Output: Treatment of high blood pressure and gain in event-free life expectancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Kassai B, Boissel J-P, Cucherat M, et al. study?. ### Response: Treatment of high blood pressure and gain in event-free life expectancy.


Instruction: What is the relationship between blood pressure and gain in event-free life expectancy?

Output: Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between blood pressure and gain in event-free life expectancy?. ### Response: Treatment.


Instruction: When was Vasc Health Risk Manag published?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Vasc Health Risk Manag published?. ### Response: 2005.


Instruction: Where can you find ACC/AHA Pooled Cohort Equations?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find ACC/AHA Pooled Cohort Equations?. ### Response: http://tools.acc.org/ASCVD-Risk-Estimator/..


Instruction: What is statin used for in patients with stable coronary disease?

Output: prevention of coronary disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is statin used for in patients with stable coronary disease?. ### Response: prevention of coronary disease.


Instruction: What is the difference between statin and usual-dosesimvastatin for secondary prevention?

Output: antioxidant vitamins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between statin and usual-dosesimvastatin for secondary prevention?. ### Response: antioxidant vitamins.


Instruction: Which study group evaluated the decrease in end points through aggressive lipi dLowering?

Output: IDEAL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which study group evaluated the decrease in end points through aggressive lipi dLowering?. ### Response: IDEAL.


Instruction: What is the name of the dLowering Study Group?

Output: Incremental Decrease in End Points Through Aggressive Lipi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the dLowering Study Group?. ### Response: Incremental Decrease in End Points Through Aggressive Lipi.


Instruction: High-dose atorvastatin vs usual-dosesimvastatine for secondary prevention after myocardial infarction: theIDEAL study: a randomized controlled trial?

Output: Incremental Decrease in End Points Through Aggressive Lipi dLowering (IDEAL) Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: High-dose atorvastatin vs usual-dosesimvastatine for secondary prevention after myocardial infarction: theIDEAL study: a randomized controlled trial?. ### Response: Incremental Decrease in End Points Through Aggressive Lipi dLowering (IDEAL) Study Group.


Instruction: Cholesterol Treatment Trialists' (CTT) Collaborators: Baigent C, Blackwell L, Emberson J, Holland LE, Reith C, Bhala N, Peto R, BarnesEH, and what is a name of a group of study group?

Output: Keech A, Simes J, Collins R

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cholesterol Treatment Trialists' (CTT) Collaborators: Baigent C, Blackwell L, Emberson J, Holland LE, Reith C, Bhala N, Peto R, BarnesEH, and what is a name of a group of study group?. ### Response: Keech A, Simes J, Collins R.


Instruction: How many people participated in a meta-analysis of data from 26 randomised trials?

Output: 170,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people participated in a meta-analysis of data from 26 randomised trials?. ### Response: 170,000.


Instruction: When did the Lancet 376:1670–1681.29 appear?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet 376:1670–1681.29 appear?. ### Response: 2010.


Instruction: What did the National Cholesterol Education Program Expert Panel on Detection,Evaluation, and Treatment of High Blood Blood do?

Output: Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the National Cholesterol Education Program Expert Panel on Detection,Evaluation, and Treatment of High Blood Blood do?. ### Response: Evaluation.


Instruction: What is the third report of the NCEP Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults?

Output: AdultTreatment Panel III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the third report of the NCEP Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults?. ### Response: AdultTreatment Panel III.


Instruction: What is the name of the final report published in 2002?

Output: Third Report of the National Cholesterol Edu-cation Program (NCEP) Expert Panel on Detection, Evaluation, andTreatment of High Blood Cholesterol in Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the final report published in 2002?. ### Response: Third Report of the National Cholesterol Edu-cation Program (NCEP) Expert Panel on Detection, Evaluation, andTreatment of High Blood Cholesterol in Adults.


Instruction: What are the names of the authors in 2002 in Circulation?

Output: Robinson JG, Wang S, Smith BJ, Jacobson TA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors in 2002 in Circulation?. ### Response: Robinson JG, Wang S, Smith BJ, Jacobson TA.


Instruction: In what year did the J Am Coll Cardiol publish a report?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the J Am Coll Cardiol publish a report?. ### Response: 2009.


Instruction: What effect did intensive lipid-lowering therapy have on the coronary arteries of asymptomatic subjects with elevated apolipoprotein B?

Output: delays saphenous vein graft atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What effect did intensive lipid-lowering therapy have on the coronary arteries of asymptomatic subjects with elevated apolipoprotein B?. ### Response: delays saphenous vein graft atherosclerosis.


Instruction: What is the name of the antioxidant vitamins?

Output: Simvastatin and niacin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the antioxidant vitamins?. ### Response: Simvastatin and niacin.


Instruction: Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease?

Output: High-dose atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease?. ### Response: High-dose atorvastatin.


Output: N Engl J Med.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 2001;345:1583–1592.33.. ### Response: N Engl J Med..


Instruction: Campeau L, Hunninghake DB, Knatterud GL, White CW, Domanski M, Forman SA, Gobel FL, Herd JA, Hoogwerf BJ, Rosenberg Y, and Post CABG Trial Investigators.

Output: Kn

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Campeau L, Hunninghake DB, Knatterud GL, White CW, Domanski M, Forman SA, Gobel FL, Herd JA, Hoogwerf BJ, Rosenberg Y, and Post CABG Trial Investigators.. ### Response: Kn.


Instruction: What does agressive choles-terol lowering delay in saphenous vein graft atherosclerosis in women, theelderly, and patients with associated risk factors have?

Output: NHLBI post coronaryartery bypass graft clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does agressive choles-terol lowering delay in saphenous vein graft atherosclerosis in women, theelderly, and patients with associated risk factors have?. ### Response: NHLBI post coronaryartery bypass graft clinical trial.


Instruction: What is the name of the post CABG Trial Investigator?

Output: Campeau L, Hunninghake DB, Knatterud GL, White CW, Domanski M,Forman SA, Forrester JS, Geller NL, Gobel FL, Herd JA, Hoogwerf BJ,Rosenberg Y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the post CABG Trial Investigator?. ### Response: Campeau L, Hunninghake DB, Knatterud GL, White CW, Domanski M,Forman SA, Forrester JS, Geller NL, Gobel FL, Herd JA, Hoogwerf BJ,Rosenberg Y.


Instruction: What is Gemfibrozil used for in men with low levels of high-density lipo-protein cholesterol?

Output: secondary preventio n ofcoronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Gemfibrozil used for in men with low levels of high-density lipo-protein cholesterol?. ### Response: secondary preventio n ofcoronary heart disease.


Instruction: What is the N Engl J Med. 1999;341:410-418.35?

Output: Gemfibrozil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 1999;341:410-418.35?. ### Response: Gemfibrozil.


Instruction: How long did niacin last in Coronary Drug Project patients?

Output: Fifteen year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did niacin last in Coronary Drug Project patients?. ### Response: Fifteen year.


Instruction: What is the name of the drug that can be used to treat Coronary Disease Project patients for the long term?

Output: niacin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that can be used to treat Coronary Disease Project patients for the long term?. ### Response: niacin.


Instruction: How many Stroke July 2015medical patients?

Output: 2046

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Stroke July 2015medical patients?. ### Response: 2046.


Instruction: What was demonstrated in the hematoma evacuation group with a trend toward improved outcomes?

Output: perihematomal edema

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was demonstrated in the hematoma evacuation group with a trend toward improved outcomes?. ### Response: perihematomal edema.


Instruction: A randomized phase 3 clinical trial of what is currently in progress?

Output: minimally invasive hematoma evacuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A randomized phase 3 clinical trial of what is currently in progress?. ### Response: minimally invasive hematoma evacuation.


Instruction: What is currently in progress?

Output: A random-ized phase 3 clinical trial of minimally invasive hematoma evacuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is currently in progress?. ### Response: A random-ized phase 3 clinical trial of minimally invasive hematoma evacuation.


Instruction: What remains controversial regarding the timing of surgery for ICH?

Output: the usefulness of surgery is not well established

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains controversial regarding the timing of surgery for ICH?. ### Response: the usefulness of surgery is not well established.


Instruction: How long after symptom onset does surgery last?

Output: 4 to 96 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after symptom onset does surgery last?. ### Response: 4 to 96 hours.


Instruction: What did STICH II suggest for patients operated on before 21 hours from ictus?

Output: better outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did STICH II suggest for patients operated on before 21 hours from ictus?. ### Response: better outcome.


Instruction: How many patients were in a meta-analysis of 8 trials of surgery for ICH?

Output: 2186

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were in a meta-analysis of 8 trials of surgery for ICH?. ### Response: 2186.


Instruction: What did surgery improve if performed within 8 hours of hemorrhage?

Output: outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did surgery improve if performed within 8 hours of hemorrhage?. ### Response: outcome.


Instruction: When was ultra-early craniotomy performed?

Output: within 4 hours from ictus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was ultra-early craniotomy performed?. ### Response: within 4 hours from ictus.


Instruction: How many hours of hemorrhage?

Output: 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours of hemorrhage?. ### Response: 8.


Instruction: What was associated with an increased risk of rebleeding in a study that involved 24 patients?

Output: Ultra-early craniotomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with an increased risk of rebleeding in a study that involved 24 patients?. ### Response: Ultra-early craniotomy.


Instruction: Who should undergo surgical removal of the hemorrhage as soon as possible?

Output: lar obstruction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should undergo surgical removal of the hemorrhage as soon as possible?. ### Response: lar obstruction.


Instruction: What is not recommended for patients with brainstem compression and/or hydrocephalus?

Output: Initial treatment of these patients with ventricular drainage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for patients with brainstem compression and/or hydrocephalus?. ### Response: Initial treatment of these patients with ventricular drainage.


Instruction: What is recommended for most patients with supratentorial ICH?

Output: surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for most patients with supratentorial ICH?. ### Response: surgery.


Instruction: What is the usefulness of surgery not well established for?

Output: most patients with supratentorial ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the usefulness of surgery not well established for?. ### Response: most patients with supratentorial ICH.


Instruction: What is not clearly beneficial compared with hematoma evacu-ation when patients deteriorate?

Output: A policy of early hematoma evacuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not clearly beneficial compared with hematoma evacu-ation when patients deteriorate?. ### Response: A policy of early hematoma evacuation.


Instruction: What might be considered as a recomendation in deteriorating patients?

Output: Ultra-early craniotomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered as a recomendation in deteriorating patients?. ### Response: Ultra-early craniotomy.


Instruction: What might be considered as a life-saving measure in deteriorating patients?

Output: Supratentorial hematoma evacuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered as a life-saving measure in deteriorating patients?. ### Response: Supratentorial hematoma evacuation.


Instruction: What might reduce mortality for patients with supratentorial ICH who are in a coma?

Output: DC with or without hematoma evacuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might reduce mortality for patients with supratentorial ICH who are in a coma?. ### Response: DC with or without hematoma evacuation.


Instruction: What is a class IIb; Level of Evidence C?

Output: Supratentorial hematoma evacuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIb; Level of Evidence C?. ### Response: Supratentorial hematoma evacuation.


Instruction: What is the effectiveness of minimally invasive clot evacuation?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effectiveness of minimally invasive clot evacuation?. ### Response: uncertain.


Instruction: What class is thrombolytic usage uncertain?

Output: Class IIb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What class is thrombolytic usage uncertain?. ### Response: Class IIb.


Instruction: What is the Level of Evidence B?

Output: Class I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence B?. ### Response: Class I.


Instruction: How many factors have been identified with outcome after acute ICH?

Output: a wide range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many factors have been identified with outcome after acute ICH?. ### Response: a wide range.


Instruction: What were the factors that led to the development of models to predict mortality and functional outcome?

Output: individual patient characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the factors that led to the development of models to predict mortality and functional outcome?. ### Response: individual patient characteristics.


Instruction: What are the prediction models for?

Output: individual patient characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the prediction models for?. ### Response: individual patient characteristics.


Instruction: What is the name of the EFSA Panel on Nutrition?

Output: Novel Foods and Food Allergens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the EFSA Panel on Nutrition?. ### Response: Novel Foods and Food Allergens.


Instruction: What are the reference values for sodium in the diet?

Output: 17:191 .73

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the reference values for sodium in the diet?. ### Response: 17:191 .73.


Instruction: When did the JAMA Intern Med publish?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the JAMA Intern Med publish?. ### Response: 2013.


Instruction: What are high-risk individuals with type 2 diabetes mellitus?

Output: Diet and kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are high-risk individuals with type 2 diabetes mellitus?. ### Response: Diet and kidney disease.


Instruction: What is the relationship between estimatedsodium and potassium excretion and subsequent renal outcomes?

Output: Kidney Int . 2014;86:1205 –1212 .75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between estimatedsodium and potassium excretion and subsequent renal outcomes?. ### Response: Kidney Int . 2014;86:1205 –1212 .75.


Instruction: What are the results of a cooking, and exercise program for patients with kidney disease?

Output: Self-management and biomedicaloutcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of a cooking, and exercise program for patients with kidney disease?. ### Response: Self-management and biomedicaloutcomes.


Instruction: What is the effect of exercise training on GFR, vascular health and cardiorespiratory fitness in patients with CKD?

Output: estimated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of exercise training on GFR, vascular health and cardiorespiratory fitness in patients with CKD?. ### Response: estimated.


Instruction: What is the name of the pilot randomized controlled trial of short-term aerobic exercise andvascular function in CKD stage 3?

Output: Am J Kidney Dis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pilot randomized controlled trial of short-term aerobic exercise andvascular function in CKD stage 3?. ### Response: Am J Kidney Dis.


Instruction: How many patients were enrolled in the pilot study?

Output: 65:425–434.77

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the pilot study?. ### Response: 65:425–434.77.


Instruction: What is the name of the randomized clinical trial that evaluated the effects of diet and exercise on CKD patients?

Output: Diabetol . 2009;8:62 .82. Van Craenenbroeck AH, Van Craenenbroeck EM, Van Ackeren K, et al.Effect of moderate aerobic exercise training on endothelial functionand arterial stiffness in CKD stages 3-4: a randomized controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial that evaluated the effects of diet and exercise on CKD patients?. ### Response: Diabetol . 2009;8:62 .82. Van Craenenbroeck AH, Van Craenenbroeck EM, Van Ackeren K, et al.Effect of moderate aerobic exercise training on endothelial functionand arterial stiffness in CKD stages 3-4: a randomized controlled trial.


Instruction: How many patients were treated with exercise training in 2014?

Output: 64:383 –393.84

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with exercise training in 2014?. ### Response: 64:383 –393.84.


Instruction: What is the name of the randomized clinical trial in patients with moderate to severe CKD?

Output: randomized controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial in patients with moderate to severe CKD?. ### Response: randomized controlled trial.


Instruction: What is Leehey DJ, Collins E, Kramer HJ, et al. Structured exercise in obese diabetic patients with chronic kidney disease: a randomized controlled trial?

Output: Am J Nephrol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Leehey DJ, Collins E, Kramer HJ, et al. Structured exercise in obese diabetic patients with chronic kidney disease: a randomized controlled trial?. ### Response: Am J Nephrol.


Instruction: What is the effect of moderate aerobic exercise training on endothelial function and arterial stiffness?

Output: a randomized controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of moderate aerobic exercise training on endothelial function and arterial stiffness?. ### Response: a randomized controlled trial.