Instruction: How many events of renal failure or progression to dialysis were reported in a single study?

Output: zero

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many events of renal failure or progression to dialysis were reported in a single study?. ### Response: zero.


Instruction: What was the evidence rated as for the comparison of high dose ARB with low dose?

Output: very low quali ty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the evidence rated as for the comparison of high dose ARB with low dose?. ### Response: very low quali ty.


Instruction: What was suggested a clinically important reduction in HF?

Output: high dose ARBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was suggested a clinically important reduction in HF?. ### Response: high dose ARBs.


Instruction: What was very low quali ties?

Output: high dose ARBs with low dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was very low quali ties?. ### Response: high dose ARBs with low dose.


Instruction: What should be carefully implemented and individualized in older adults to avoid det-rimental effects such as loss of lean body/muscle mass and nutritional deficiencies?

Output: interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be carefully implemented and individualized in older adults to avoid det-rimental effects such as loss of lean body/muscle mass and nutritional deficiencies?. ### Response: interventions.


Instruction: What is associated with moderate improvement in BP, triglyceride and glucose levels?

Output: Clinically meaningful weight loss

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with moderate improvement in BP, triglyceride and glucose levels?. ### Response: Clinically meaningful weight loss.


Instruction: What does LDL-C stand for?

Output: low-density lipoprotein cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LDL-C stand for?. ### Response: low-density lipoprotein cholesterol.


Instruction: What is a term for low-density lipoprotein cholesterol?

Output: LDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for low-density lipoprotein cholesterol?. ### Response: LDL-C.


Instruction: How long does it take for a trained interventionist to complete a weight loss program?

Output: ≥14 sessions in 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a trained interventionist to complete a weight loss program?. ### Response: ≥14 sessions in 6 months.


Instruction: What type of interventionist work best?

Output: trained

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of interventionist work best?. ### Response: trained.


Instruction: Other than electronically delivered weight-loss programs with per-sonalized feedback, what other modalities have shown moderate results?

Output: commercial-based programs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Other than electronically delivered weight-loss programs with per-sonalized feedback, what other modalities have shown moderate results?. ### Response: commercial-based programs.


Instruction: What consists of a structured program that includes regular self-monitoring?

Output: Comprehensive lifestyle intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What consists of a structured program that includes regular self-monitoring?. ### Response: Comprehensive lifestyle intervention.


Instruction: What is recommended for initial weight loss?

Output: Increased physical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for initial weight loss?. ### Response: Increased physical activity.


Instruction: How many minutes/week is recommended to main-tain weight loss or weight gain?

Output: 200 to 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many minutes/week is recommended to main-tain weight loss or weight gain?. ### Response: 200 to 300.


Instruction: What are the recommended levels of physical activity?

Output: 200 to 300 minutes/week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommended levels of physical activity?. ### Response: 200 to 300 minutes/week.


Instruction: How many minutes/week are recommended to main-tain weight loss or minimize weight regain after 1 year?

Output: 200 to 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many minutes/week are recommended to main-tain weight loss or minimize weight regain after 1 year?. ### Response: 200 to 300.


Instruction: Adults with obesity are typically prescribed a diet designed to reduce caloric intake by 500 kcal/day from baseline?

Output: S4.1-10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults with obesity are typically prescribed a diet designed to reduce caloric intake by 500 kcal/day from baseline?. ### Response: S4.1-10.


Instruction: Women are typically restricted to what?

Output: 1200 to 1500 kcal/day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Women are typically restricted to what?. ### Response: 1200 to 1500 kcal/day.


Instruction: What is the definition of a very low-calorie diet?

Output: <800 kcal/day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of a very low-calorie diet?. ### Response: <800 kcal/day.


Instruction: What should be prescribed only in limited circumstances and by trained clinicians in a medical care setting with the patient under medical supervision?

Output: -low-calorie diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be prescribed only in limited circumstances and by trained clinicians in a medical care setting with the patient under medical supervision?. ### Response: -low-calorie diet.


Instruction: What type of intervention has been shown to produce on average 8 kg of weight loss in the short term?

Output: Comprehensive life-style intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention has been shown to produce on average 8 kg of weight loss in the short term?. ### Response: Comprehensive life-style intervention.


Instruction: What is the average length of a comprehensive life-style intervention?

Output: ≤6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average length of a comprehensive life-style intervention?. ### Response: ≤6 months.


Instruction: Longer interventions after 1 year are associated with gradual weight gain of 1 or 2 kg/year compared with what type of care?

Output: usual care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Longer interventions after 1 year are associated with gradual weight gain of 1 or 2 kg/year compared with what type of care?. ### Response: usual care.


Instruction: Weight loss of 5% to 10% of initial weight achieved through comprehensive lifestyle interven-tion has been shown to improve what?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Weight loss of 5% to 10% of initial weight achieved through comprehensive lifestyle interven-tion has been shown to improve what?. ### Response: BP.


Instruction: What has been shown to improve BP, delay the onset of T2DM, and improve glycemic control in t2DM?

Output: Weight loss of 5% to 10% of initial weight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to improve BP, delay the onset of T2DM, and improve glycemic control in t2DM?. ### Response: Weight loss of 5% to 10% of initial weight.


Instruction: What are measures used to estimate body fat and quan-tify the associated health risks?

Output: BMI, waist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are measures used to estimate body fat and quan-tify the associated health risks?. ### Response: BMI, waist.


Instruction: What year was the 2013 ACCF/AHA Guideline for the Management of Heart Failure released?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the 2013 ACCF/AHA Guideline for the Management of Heart Failure released?. ### Response: 2016.


Instruction: Who was the official reviewer for the 2017 ACC/ AHA/HFSA Task Force?

Output: Akshay S. Desai

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the official reviewer for the 2017 ACC/ AHA/HFSA Task Force?. ### Response: Akshay S. Desai.


Instruction: Who is an official reviewer for the ACC/AHA Task Force on Clinical Practice Guidelines?

Output: Kim K. Birtcher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is an official reviewer for the ACC/AHA Task Force on Clinical Practice Guidelines?. ### Response: Kim K. Birtcher.


Instruction: Who is a Clinical Professor at the University of Houston College of Pharmacy?

Output: Jones & Bartlett

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Clinical Professor at the University of Houston College of Pharmacy?. ### Response: Jones & Bartlett.


Instruction: What is the name of the Director of Heart Failure Disease Management?

Output: Akshay S. Desai

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Director of Heart Failure Disease Management?. ### Response: Akshay S. Desai.


Instruction: Who is the Chief of Cardiology at AHAMichael E. DeBakey VA Medical Center?

Output: Anita Deswal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chief of Cardiology at AHAMichael E. DeBakey VA Medical Center?. ### Response: Anita Deswal.


Instruction: Who is Director of Heart Failure Program at Baylor?

Output: Akshay S. Desai

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Director of Heart Failure Program at Baylor?. ### Response: Akshay S. Desai.


Instruction: Who is the Chief of Cardiology at VA Medical Center?

Output: AHAMichael E. DeBakey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chief of Cardiology at VA Medical Center?. ### Response: AHAMichael E. DeBakey.


Instruction: What is the Director of Heart Failure Program at Baylor College of Medicine?

Output: Anita Deswal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Director of Heart Failure Program at Baylor College of Medicine?. ### Response: Anita Deswal.


Instruction: Who is the Endowed Chair for Excellence in Cardiac Care?

Output: Robert and Georgia Roth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Endowed Chair for Excellence in Cardiac Care?. ### Response: Robert and Georgia Roth.


Instruction: What is the name of the official reviewer at AHAMontefiore Medical Center?

Output: Akshay S. Desai

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the official reviewer at AHAMontefiore Medical Center?. ### Response: Akshay S. Desai.


Instruction: Who is the official reviewer for the ACC Board of Governors?

Output: Geetha Raghuveer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the official reviewer for the ACC Board of Governors?. ### Response: Geetha Raghuveer.


Instruction: What is the name of the professor of pediatrics at the University of Missouri-Kansas City School of Medicine?

Output: Geetha Raghuveer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of pediatrics at the University of Missouri-Kansas City School of Medicine?. ### Response: Geetha Raghuveer.


Instruction: Who is the official reviewer for the ACC Board of Trustees?

Output: Mary Norine Walsh

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the official reviewer for the ACC Board of Trustees?. ### Response: Mary Norine Walsh.


Instruction: What is the name of the organization that is responsible for Circulation/Circulation: Heart Failure?

Output: HFSA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that is responsible for Circulation/Circulation: Heart Failure?. ### Response: HFSA.


Instruction: Who is the Medical Director of St Vincent Heart Center of Indiana?

Output: Mary Norine Walsh

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Medical Director of St Vincent Heart Center of Indiana?. ### Response: Mary Norine Walsh.


Instruction: What is the name of the hospital that has a heart failure and a cardiac transplantation division?

Output: St Vincent Heart Center of Indiana

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the hospital that has a heart failure and a cardiac transplantation division?. ### Response: St Vincent Heart Center of Indiana.


Instruction: When was this article published?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: May 3, 2023.


Instruction: Where can this article be found?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can this article be found?. ### Response: http://ahajournals.org.


Instruction: What is a potential link between the renin-angiotensin system and atherosclero-sis?

Output: Blood pressure-dependent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential link between the renin-angiotensin system and atherosclero-sis?. ### Response: Blood pressure-dependent.


Instruction: What is the effect of captopril onmortality and morbidity in patients with left ventricular dysfunction after myocardial infarction?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of captopril onmortality and morbidity in patients with left ventricular dysfunction after myocardial infarction?. ### Response: Effect.


Instruction: Who conducted the survival and ventricularenlargement trial?

Output: The SAVE Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who conducted the survival and ventricularenlargement trial?. ### Response: The SAVE Investigators.


Instruction: What is ramipril used for in people with diabetes mellitus?

Output: cardiovascular and microvascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ramipril used for in people with diabetes mellitus?. ### Response: cardiovascular and microvascular outcomes.


Instruction: What are the results of the HOPE study and MICRO-HOPE substudy?

Output: Effects of ramipril on cardiovascular and microvascular outcomes inpeople with diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the HOPE study and MICRO-HOPE substudy?. ### Response: Effects of ramipril on cardiovascular and microvascular outcomes inpeople with diabetes mellitus.


Instruction: What is the effect of angi oten-sinconverting enzyme inhibition in low-risk patients aftercoronary artery bypass surgery?

Output: Effects of angi oten-sinconverting enzyme inhibition in low-risk patients earl y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of angi oten-sinconverting enzyme inhibition in low-risk patients aftercoronary artery bypass surgery?. ### Response: Effects of angi oten-sinconverting enzyme inhibition in low-risk patients earl y.


Instruction: Circulation. 2008;117:24–31.804.

Output: Effects of angi oten-sinconverting enzyme inhibition in low-risk patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2008;117:24–31.804.. ### Response: Effects of angi oten-sinconverting enzyme inhibition in low-risk patients.


Instruction: Blood pressure-dependent andindependent effects of agents that inhibit the renin-angiotensin system.

Output: Turnbull F, Neal B, Pfeffer M, et al. Blood pressure-dependent andindependent effects of agents that inhibit the renin-angiotensin system.J Hypertens. 2007;25:951–8.805

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood pressure-dependent andindependent effects of agents that inhibit the renin-angiotensin system.. ### Response: Turnbull F, Neal B, Pfeffer M, et al. Blood pressure-dependent andindependent effects of agents that inhibit the renin-angiotensin system.J Hypertens. 2007;25:951–8.805.


Instruction: What was the difference between losartan and atenolol?

Output: Regression of electrocardio-graphic left ventricular hypertrophy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between losartan and atenolol?. ### Response: Regression of electrocardio-graphic left ventricular hypertrophy.


Instruction: What is the LIFE study?

Output: TheLosartan Intervention for Endpoint reduction in Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LIFE study?. ### Response: TheLosartan Intervention for Endpoint reduction in Hypertension.


Instruction: How many people died from avian influenza in 2003?

Output: 108:684

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people died from avian influenza in 2003?. ### Response: 108:684.


Instruction: What is a secondary prevention for cardiovascular disease?

Output: Influenza vaccination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a secondary prevention for cardiovascular disease?. ### Response: Influenza vaccination.


Instruction: What is an advisory from the American Heart Association/American College of Car-diology?

Output: Influenza vaccination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an advisory from the American Heart Association/American College of Car-diology?. ### Response: Influenza vaccination.


Instruction: When was the J Am Coll Cardiol. 2006?

Output: 2006;48:1498–502.808

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol. 2006?. ### Response: 2006;48:1498–502.808.


Instruction: What is the effect of annual influenza vaccination on winter mortality in elderly peopl e withchronic heart disease?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of annual influenza vaccination on winter mortality in elderly peopl e withchronic heart disease?. ### Response: Effects.


Instruction: When did Eur Heart J. 2008:30:209-16.809?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 2008:30:209-16.809?. ### Response: 2008.


Instruction: What did Couch RB, Winokur P, Brady R, et al. say about the safety and immunogenicity of a high dose trivalent influenza vaccine?

Output: Safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Couch RB, Winokur P, Brady R, et al. say about the safety and immunogenicity of a high dose trivalent influenza vaccine?. ### Response: Safety.


Instruction: What is the effect of high doses of influenzavaccine on antibody responses in elderly persons?

Output: Safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of high doses of influenzavaccine on antibody responses in elderly persons?. ### Response: Safety.


Instruction: What is a randomized trial of estrogen plusprogestin for in post-menopausal women?

Output: secondary prevention of coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomized trial of estrogen plusprogestin for in post-menopausal women?. ### Response: secondary prevention of coronary heart disease.


Instruction: In what year did ArchIntern Med publish a 166-page report on influenza vaccine safety?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did ArchIntern Med publish a 166-page report on influenza vaccine safety?. ### Response: 2006.


Instruction: What is the name of the research group that studies the secondary prevention of coronary heart disease in post-menopausal women?

Output: Heart and Estrogen/progestin Replacement Study(HERS) Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the research group that studies the secondary prevention of coronary heart disease in post-menopausal women?. ### Response: Heart and Estrogen/progestin Replacement Study(HERS) Research Group.


Instruction: When was the Heart and Estrogen/progestin Replacement Study conducted?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Heart and Estrogen/progestin Replacement Study conducted?. ### Response: 1998.


Instruction: What is conjugatedequine estrogen used for in women with hysterectomy?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is conjugatedequine estrogen used for in women with hysterectomy?. ### Response: Effects.


Instruction: What is the name of the study that evaluated estrogen plus progestin in healthy postmenopausal women?

Output: Women’s Health Initiative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated estrogen plus progestin in healthy postmenopausal women?. ### Response: Women’s Health Initiative.


Instruction: What are the main results of this study?

Output: Risks and benefits ofestrogen plus progestin in healthy postmenopausal women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the main results of this study?. ### Response: Risks and benefits ofestrogen plus progestin in healthy postmenopausal women.


Instruction: What is the name of the randomized controlled trial that evaluated postmenopausal women?

Output: Women’s Health Initiative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial that evaluated postmenopausal women?. ### Response: Women’s Health Initiative.


Instruction: When was the JAMA published?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 1998.


Instruction: What is the 2017 ACC/AHA/HFSA Heart Failure Focused UpdateCirculation. 2017;136:e137–e161?

Output: 10.1161/CIR.0000000000000509

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 ACC/AHA/HFSA Heart Failure Focused UpdateCirculation. 2017;136:e137–e161?. ### Response: 10.1161/CIR.0000000000000509.


Instruction: What do you need to consult the full-text version of the 2013 HF guideline9?

Output: text and evidence tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do you need to consult the full-text version of the 2013 HF guideline9?. ### Response: text and evidence tables.


Instruction: What will be incorporated into the full-text guideline in the future?

Output: Individual recom-mendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will be incorporated into the full-text guideline in the future?. ### Response: Individual recom-mendations.


Instruction: Recommendations from the prior guideline that remain current have been included for what reason?

Output: completeness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recommendations from the prior guideline that remain current have been included for what reason?. ### Response: completeness.


Instruction: What reflects the COR/LOE system used when the recommendations were originally developed?

Output: LOE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reflects the COR/LOE system used when the recommendations were originally developed?. ### Response: LOE.


Instruction: What are LOE B and C subcategorized for greater specificity?

Output: COR/LOE system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are LOE B and C subcategorized for greater specificity?. ### Response: COR/LOE system.


Instruction: The section numbers corre-spond to what?

Output: the full-text guideline sections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The section numbers corre-spond to what?. ### Response: the full-text guideline sections.


Instruction: How do the section numbers relate to the full-text guideline sections?

Output: corre-spond

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do the section numbers relate to the full-text guideline sections?. ### Response: corre-spond.


Instruction: Who were invited to participate in this focused update?

Output: representative members of the 2013 HF guideline writing committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were invited to participate in this focused update?. ### Response: representative members of the 2013 HF guideline writing committee.


Instruction: What is the name of the new writing group?

Output: 2017 HF focused update writing group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the new writing group?. ### Response: 2017 HF focused update writing group.


Instruction: What is the 2017 HF focused update writing group referred to as?

Output: Organization of the Writing Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 HF focused update writing group referred to as?. ### Response: Organization of the Writing Group.


Instruction: Members were required to disclose all RWI rel-evant to the data under consideration.

Output: 2017 HF focused update writing group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Members were required to disclose all RWI rel-evant to the data under consideration.. ### Response: 2017 HF focused update writing group.


Instruction: What are transplantation specialists, electrophysiologists, pharmacists, and general internists?

Output: general cardiolo-gists, HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are transplantation specialists, electrophysiologists, pharmacists, and general internists?. ### Response: general cardiolo-gists, HF.


Instruction: What group included representatives from the ACC, AHA, and HFSA?

Output: 2017 HF focused update writing group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group included representatives from the ACC, AHA, and HFSA?. ### Response: 2017 HF focused update writing group.


Instruction: How many official reviewers reviewed the focused update?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many official reviewers reviewed the focused update?. ### Response: 2.


Instruction: How many reviewers were nominated by the ACC, AHA, and HFSA?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many reviewers were nominated by the ACC, AHA, and HFSA?. ### Response: 2.


Instruction: Who were the reviewers from?

Output: American Academy of Family Physicians, American College of Chest Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were the reviewers from?. ### Response: American Academy of Family Physicians, American College of Chest Physicians.


Instruction: What was the focus update reviewed by?

Output: 2 official reviewers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus update reviewed by?. ### Response: 2 official reviewers.


Instruction: How many in-dividual content reviewers contributed to this document?

Output: 19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many in-dividual content reviewers contributed to this document?. ### Response: 19.


Instruction: What is the name of the document where reviewers' RWI information is published?

Output: Appendix 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document where reviewers' RWI information is published?. ### Response: Appendix 2.


Instruction: Which governing bodies approved this document for publication?

Output: ACC, AHA, and HFSA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which governing bodies approved this document for publication?. ### Response: ACC, AHA, and HFSA.


Instruction: What is BNP?

Output: B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is BNP?. ### Response: B-type natriuretic peptide.


Instruction: What is N-terminal pro-B-type natriuretic peptide?

Output: NT-proBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is N-terminal pro-B-type natriuretic peptide?. ### Response: NT-proBNP.


Instruction: How have biomarkers been used to establish the presence of HF?

Output: BiomarkersAssays for BNP (B-type natriuretic peptide) and NT-proBNP (N-terminal pro-B-type natriuretic peptide),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How have biomarkers been used to establish the presence of HF?. ### Response: BiomarkersAssays for BNP (B-type natriuretic peptide) and NT-proBNP (N-terminal pro-B-type natriuretic peptide),.


Instruction: What is a substrate for neprilysin?

Output: BNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a substrate for neprilysin?. ### Response: BNP.


Instruction: What increases BNP levels12?

Output: ARNI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases BNP levels12?. ### Response: ARNI.


Instruction: What percentage of patients have recurrent syncope or cardiac arrest?

Output: 7% to 24%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have recurrent syncope or cardiac arrest?. ### Response: 7% to 24%.


Instruction: What is a risk factor for SCD in high-risk patients?

Output: ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for SCD in high-risk patients?. ### Response: ICD.


Instruction: What can reduce VA burden?

Output: Left cardiac sympa-thetic denervation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can reduce VA burden?. ### Response: Left cardiac sympa-thetic denervation.


Instruction: How many high-risk patients experience at least 1 recurrence?

Output: up to 27%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many high-risk patients experience at least 1 recurrence?. ### Response: up to 27%.


Instruction: What may be more effective in patients with long QT syndrome?

Output: Left cardiac sympathetic denervation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be more effective in patients with long QT syndrome?. ### Response: Left cardiac sympathetic denervation.


Instruction: What may be more effective in patients with long QT syndrome type 1 and 3?

Output: Left cardiac sympathetic denervation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be more effective in patients with long QT syndrome type 1 and 3?. ### Response: Left cardiac sympathetic denervation.


Instruction: Complications related to left cardiac sympathetic denervation occur in 8% to what percentage of patients?

Output: 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Complications related to left cardiac sympathetic denervation occur in 8% to what percentage of patients?. ### Response: 20%.


Instruction: What may occur due to noncompliance with medications or proarrhythmia?

Output: Syncope in patients with long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may occur due to noncompliance with medications or proarrhythmia?. ### Response: Syncope in patients with long QT syndrome.


Instruction: What type of syncope can occur due to noncompliance with medications or proarrhythmia from concur -rent medications?

Output: vasovagal syncope

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of syncope can occur due to noncompliance with medications or proarrhythmia from concur -rent medications?. ### Response: vasovagal syncope.


Instruction: What is important in clinical evaluation that incorporates consideration of genotype, QTc interval, medication compliance, and shared decision-making regarding the need to change or escalate therapy?

Output: S7.9.1.1-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important in clinical evaluation that incorporates consideration of genotype, QTc interval, medication compliance, and shared decision-making regarding the need to change or escalate therapy?. ### Response: S7.9.1.1-5.


Instruction: Use of additional medica-tions is guided by what type of syndrome?

Output: long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Use of additional medica-tions is guided by what type of syndrome?. ### Response: long QT syndrome.


Instruction: What is guided by long QT syndrome type?

Output: Use of additional medica-tions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is guided by long QT syndrome type?. ### Response: Use of additional medica-tions.


Instruction: What color corresponds to Class of Recommendation in Table 1?

Output: Colors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What color corresponds to Class of Recommendation in Table 1?. ### Response: Colors.


Instruction: How is ICD candidacy determined?

Output: functional status, life expectancy, or patient preference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is ICD candidacy determined?. ### Response: functional status, life expectancy, or patient preference.


Instruction: What does LQTS stand for?

Output: long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LQTS stand for?. ### Response: long QT syndrome.


Instruction: What is the onset of symptoms at 10 years of age?

Output: <10 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the onset of symptoms at 10 years of age?. ### Response: <10 years of age.


Instruction: How long is the long QT syndrome?

Output: type 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the long QT syndrome?. ### Response: type 3.


Instruction: VT stands for what?

Output: ventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: VT stands for what?. ### Response: ventricular tachycardia.


Instruction: What does ICD stand for?

Output: implantable cardioverter-defibrillator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ICD stand for?. ### Response: implantable cardioverter-defibrillator.


Instruction: What is LQTS short QT syndrome?

Output: long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LQTS short QT syndrome?. ### Response: long QT syndrome.


Instruction: Where does VT stand for ventricular tachycardia?

Output: VT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does VT stand for ventricular tachycardia?. ### Response: VT.


Instruction: What factors are associated with antihypertensive medication non-adherence: a systematic review?

Output: van der Laan DM, Elders PJM, Boons CCLM, et al. Factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What factors are associated with antihypertensive medication non-adherence: a systematic review?. ### Response: van der Laan DM, Elders PJM, Boons CCLM, et al. Factors.


Instruction: What does Claxton AJ, Cramer J, Pierce C. A systematic review of the associa-tions between dose regimens and medication compliance?

Output: 115

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Claxton AJ, Cramer J, Pierce C. A systematic review of the associa-tions between dose regimens and medication compliance?. ### Response: 115.


Instruction: What is the relationship between dai-ly dose frequency and adherence to antihypertensive pharmacotherapy?

Output: evidence from a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relationship between dai-ly dose frequency and adherence to antihypertensive pharmacotherapy?. ### Response: evidence from a meta-analysis.


Instruction: What does Clin Ther. 2001;23:1296–310?

Output: A systematic review of the associa-tions between dose regimens and medication compliance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Clin Ther. 2001;23:1296–310?. ### Response: A systematic review of the associa-tions between dose regimens and medication compliance.


Instruction: How did Iskedjian M, Einarson TR, MacKeigan LD, et al. determine adherence?

Output: meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Iskedjian M, Einarson TR, MacKeigan LD, et al. determine adherence?. ### Response: meta-analysis.


Instruction: Who developed and tested the Hill-Bone Compliance to High Blood Pressure Therapy Scale?

Output: Kim MT, Hill MN, Bone LR, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed and tested the Hill-Bone Compliance to High Blood Pressure Therapy Scale?. ### Response: Kim MT, Hill MN, Bone LR, et al.


Instruction: What year did the Prog Cardiovasc Nurs issue 15:90–6?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Prog Cardiovasc Nurs issue 15:90–6?. ### Response: 2000.


Instruction: Where can you find the Pharmacy Quality Alliance?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the Pharmacy Quality Alliance?. ### Response: https://www.pqaalliance.org/..


Instruction: When is PDC for antihypertensive medications?

Output: proportion of days covered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is PDC for antihypertensive medications?. ### Response: proportion of days covered.


Instruction: What is the PDC for antihypertensive and antidiabetic medications?

Output: proportion of days covered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PDC for antihypertensive and antidiabetic medications?. ### Response: proportion of days covered.


Instruction: Where can I find an evaluation guide for grantees?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can I find an evaluation guide for grantees?. ### Response: https://www.cdc.gov/dhdsp/docs/med-adherence-evaluation-tool.pdf.


Instruction: How can we improve adherence to blood pressure-lowering medication in ambulatory care?

Output: Systematic review of randomized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can we improve adherence to blood pressure-lowering medication in ambulatory care?. ### Response: Systematic review of randomized controlled trials.


Instruction: What is the name of the systematic review of randomized controlled trials?

Output: Arch Intern Med.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of randomized controlled trials?. ### Response: Arch Intern Med..


Instruction: When did Arch Intern Med issue 164: 722-732?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Arch Intern Med issue 164: 722-732?. ### Response: 2004.


Instruction: What is a systolic blood pressure target and time to intensification?

Output: Optimal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systolic blood pressure target and time to intensification?. ### Response: Optimal.


Instruction: What is the name of the cohort study that was conducted in 2015?

Output: Blood Pressure Lowering Treatment Trialists’ Collaboration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the cohort study that was conducted in 2015?. ### Response: Blood Pressure Lowering Treatment Trialists’ Collaboration.


Instruction: What is one of the effects of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure?

Output: blood pressure reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the effects of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure?. ### Response: blood pressure reduction.


Instruction: What is a meta-analysis of antihypertensive treatment and secondary prevention of cardiovascular disease events among per -sons without hypertension?

Output: JAMA. 2011;305:913–22. 124. SPRINT Research Group, Wright JT Jr, Williamson JD, et al. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373:2103–16. 125. Blood Pressure Lowering Treatment Trialists’ Collaboration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of antihypertensive treatment and secondary prevention of cardiovascular disease events among per -sons without hypertension?. ### Response: JAMA. 2011;305:913–22. 124. SPRINT Research Group, Wright JT Jr, Williamson JD, et al. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373:2103–16. 125. Blood Pressure Lowering Treatment Trialists’ Collaboration.


Instruction: What is the name of the randomized trial of intensive versus standard blood pressure control?

Output: SPRINT Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of intensive versus standard blood pressure control?. ### Response: SPRINT Research Group.


Instruction: What is the name of the randomized trial of intensive versus standard blood-pressure control?

Output: SPRINT Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of intensive versus standard blood-pressure control?. ### Response: SPRINT Research Group.


Instruction: What is a meta-analysis of individual patient data based on?

Output: cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of individual patient data based on?. ### Response: cardiovascular risk.


Instruction: What is the effect of absolute cardiovascular risk, patient utilities, and costs on the decision to treat hypertension: a Markov decision analysis?

Output: The influence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of absolute cardiovascular risk, patient utilities, and costs on the decision to treat hypertension: a Markov decision analysis?. ### Response: The influence.


Instruction: On the decision to treat hypertension: a Markov decision analysis.

Output: The influence of absolute cardiovascular risk, patient utilities, and costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On the decision to treat hypertension: a Markov decision analysis.. ### Response: The influence of absolute cardiovascular risk, patient utilities, and costs.


Instruction: When did J Hypertens. 2003;21:1753-9.

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Hypertens. 2003;21:1753-9.. ### Response: 2003.


Instruction: What did van Dieren S, Kengne AP, Chalmers J, et al. study?

Output: Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did van Dieren S, Kengne AP, Chalmers J, et al. study?. ### Response: Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk.


Instruction: What is tricuspid valve replacement?

Output: transcatheter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tricuspid valve replacement?. ### Response: transcatheter.


Instruction: What is the name of the study that examined the national trends and outcomes in isolated tricusepid valve surgery?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the national trends and outcomes in isolated tricusepid valve surgery?. ### Response: J Am Coll Cardiol.


Instruction: Which year did the J Am Coll Cardiol. 201770:2953-60?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which year did the J Am Coll Cardiol. 201770:2953-60?. ### Response: 2018.


Instruction: What is a growing problem in isolated tricuspid regurgitation?

Output: Prognostic importance and pre-dictors of survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a growing problem in isolated tricuspid regurgitation?. ### Response: Prognostic importance and pre-dictors of survival.


Instruction: What is the role of preoperative factors in adverse outcome after valve replacement?

Output: survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of preoperative factors in adverse outcome after valve replacement?. ### Response: survival.


Instruction: When was Circulation.123:1929-39?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation.123:1929-39?. ### Response: 2011.


Instruction: What is the clinical context and mechanism of functional tricuspid regurgitation in patients with and without pulmo-nary hypertension?

Output: prognostic implications, mechanism, and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical context and mechanism of functional tricuspid regurgitation in patients with and without pulmo-nary hypertension?. ### Response: prognostic implications, mechanism, and management.


Instruction: Circ Cardiovasc Imaging. 2012;5:314–23.

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circ Cardiovasc Imaging. 2012;5:314–23.. ### Response: 25.


Instruction: Mutlak D, Lessick J, Reisner SA, et al.

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Mutlak D, Lessick J, Reisner SA, et al.. ### Response: 25.


Instruction: What is the frequency of apparently idiopathic tricuspid regurgitation?

Output: Echocardiography-based spectrum of severe tricuspid regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the frequency of apparently idiopathic tricuspid regurgitation?. ### Response: Echocardiography-based spectrum of severe tricuspid regurgitation.


Instruction: What year did J Am Soc Echocardiogr. 2007:20:405–8?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Am Soc Echocardiogr. 2007:20:405–8?. ### Response: 2007.


Instruction: Who is Taramasso M, Hahn RT, Alessandrini H, et al.?

Output: 26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Taramasso M, Hahn RT, Alessandrini H, et al.?. ### Response: 26.


Instruction: When did JACC Cardiovasc Interv. 2017;10:1982–90?

Output: 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JACC Cardiovasc Interv. 2017;10:1982–90?. ### Response: 27.


Instruction: What are the challenges and future directions of transcatheter tricuspid valve interven-tions?

Output: landscape

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the challenges and future directions of transcatheter tricuspid valve interven-tions?. ### Response: landscape.


Instruction: What is the J Am Coll Cardiol. 2018?

Output: 71:2935–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2018?. ### Response: 71:2935–.


Instruction: Who is the Chikwe J, Anyanwu AC?

Output: Surgical strategies for functional tricuspid regur -gitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chikwe J, Anyanwu AC?. ### Response: Surgical strategies for functional tricuspid regur -gitation.


Instruction: When was the Semin Thorac Cardiovasc Surg. 2010?

Output: 2010;22:90–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Semin Thorac Cardiovasc Surg. 2010?. ### Response: 2010;22:90–.


Instruction: What is the role of tricuspid annular systolic velocity in valve surgery?

Output: Prediction of outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of tricuspid annular systolic velocity in valve surgery?. ### Response: Prediction of outcome.


Instruction: How long did outcome trends for valve surgery last?

Output: Fifteen-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did outcome trends for valve surgery last?. ### Response: Fifteen-year.


Instruction: How many years did Rankin JS and Bolling SF study outcome trends for valve surgery in North America?

Output: Fifteen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years did Rankin JS and Bolling SF study outcome trends for valve surgery in North America?. ### Response: Fifteen.


Instruction: What is the current perspective and evolving management of tricuspid regurgitation?

Output: The tricuspid valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current perspective and evolving management of tricuspid regurgitation?. ### Response: The tricuspid valve.


Instruction: What is development of tricuspid regurgitation late after left-sided valve surgery?

Output: a single-center experience with long-term echocardiographic examinations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is development of tricuspid regurgitation late after left-sided valve surgery?. ### Response: a single-center experience with long-term echocardiographic examinations.


Instruction: What did Chopra HK, Nanda NC, Fan P, et al. use to identify the need for?

Output: two-dimensional echocardiogra-phy and Doppler color flow mapping

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Chopra HK, Nanda NC, Fan P, et al. use to identify the need for?. ### Response: two-dimensional echocardiogra-phy and Doppler color flow mapping.


Instruction: What does flow mapping identify the need for?

Output: tricuspid valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does flow mapping identify the need for?. ### Response: tricuspid valve repair.


Instruction: When did J Am Coll Cardiol. 1989:14:1266–74?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 1989:14:1266–74?. ### Response: 1989.


Instruction: What does Mahsh B, Wells F, Nashef S, et al. recommend in patients undergoing left heart valve surgery?

Output: Role of concomitant tricuspid surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Mahsh B, Wells F, Nashef S, et al. recommend in patients undergoing left heart valve surgery?. ### Response: Role of concomitant tricuspid surgery.


Instruction: What year did Eur J Cardiothorac Surg publish 43:2–8?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Eur J Cardiothorac Surg publish 43:2–8?. ### Response: 2013.


Instruction: What is Tricuspid regurgitation in mitral valve disease incidence, prognostic implications, mechanism, and management?

Output: Clinical context and mechanism of functional

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Tricuspid regurgitation in mitral valve disease incidence, prognostic implications, mechanism, and management?. ### Response: Clinical context and mechanism of functional.


Instruction: When did J Am Coll Cardiol publish 53:401–8.

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol publish 53:401–8.. ### Response: 2009.


Instruction: What did Sagie A, Schwammenthal E, Padial LR, et al. study?

Output: Determinants of functional tricuspid regurgitation in incomplete tricuspid valve closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Sagie A, Schwammenthal E, Padial LR, et al. study?. ### Response: Determinants of functional tricuspid regurgitation in incomplete tricuspid valve closure.


Instruction: What is the name of the author of the 2015 ACC/AHA/HRS SVT Guideline?

Output: Bulent Gorenek

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the author of the 2015 ACC/AHA/HRS SVT Guideline?. ### Response: Bulent Gorenek.


Instruction: Who is a professor and vice director of the Cardiology Department at the University of Oklahoma?

Output: Eskisehir Osmangazi University

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a professor and vice director of the Cardiology Department at the University of Oklahoma?. ### Response: Eskisehir Osmangazi University.


Instruction: Who is the University of Oklahoma Health Sciences Center's George Lynn Cross Research Professor Emeritus?

Output: Heart Rhythm Institute—Senior Scientific Advisor• Biosense Webster

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the University of Oklahoma Health Sciences Center's George Lynn Cross Research Professor Emeritus?. ### Response: Heart Rhythm Institute—Senior Scientific Advisor• Biosense Webster.


Instruction: What is the title of the Content Reviewer at the London Health Science Center?

Output: Chief of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the Content Reviewer at the London Health Science Center?. ### Response: Chief of Cardiology.


Instruction: Who is a professor of Cardiology at Northwestern University?

Output: Bradley P. Knight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a professor of Cardiology at Northwestern University?. ### Response: Bradley P. Knight.


Instruction: Who is the division chief of pediatric cardiology at the University of Nebraska Medical Center?

Output: John D. Kugler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the division chief of pediatric cardiology at the University of Nebraska Medical Center?. ### Response: John D. Kugler.


Instruction: What is the name of the professor of medicine at the Mayo Clinic?

Output: Professor of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at the Mayo Clinic?. ### Response: Professor of Medicine.


Instruction: What is the name of the ACC/AHA Task Force on Clinical Practice Guidelines?

Output: Jonathan L. Halperin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACC/AHA Task Force on Clinical Practice Guidelines?. ### Response: Jonathan L. Halperin.


Instruction: Who is the Director of Cardiac Care Unit at Baylor College of Medicine?

Output: Glenn N. Levine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of Cardiac Care Unit at Baylor College of Medicine?. ### Response: Glenn N. Levine.


Instruction: Which University is the Associate Professor of Medicine at George Washington University?

Output: University of California San Francisco

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which University is the Associate Professor of Medicine at George Washington University?. ### Response: University of California San Francisco.


Instruction: What is the name of the fellowship program at the University of Michigan?

Output: Reviewer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the fellowship program at the University of Michigan?. ### Response: Reviewer.


Instruction: Who is the professor of Cardiovascular Disease?

Output: McKay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the professor of Cardiovascular Disease?. ### Response: McKay.


Instruction: Which university is Fred Morady affiliated with?

Output: University of Michigan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which university is Fred Morady affiliated with?. ### Response: University of Michigan.


Instruction: Where is Melvin Scheinman affiliated?

Output: University of California San Francisco

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Melvin Scheinman affiliated?. ### Response: University of California San Francisco.


Instruction: What is the name of the expert witness that was downloaded from http://ahajournals.org on April 23, 2023?

Output: BenefitExpert

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the expert witness that was downloaded from http://ahajournals.org on April 23, 2023?. ### Response: BenefitExpert.


Instruction: How many patients were randomized to early surgery or conservative treatment?

Output: 1033

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were randomized to early surgery or conservative treatment?. ### Response: 1033.


Instruction: How many countries participated in the trial?

Output: 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many countries participated in the trial?. ### Response: 27.


Instruction: What was the favorable outcome on the 8-point extended Glasgow Outcome Scale at 6 months?

Output: primary end point

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the favorable outcome on the 8-point extended Glasgow Outcome Scale at 6 months?. ### Response: primary end point.


Instruction: What was the primary end point of the Glasgow Outcome Scale?

Output: prognosis-based dichotomized (favorable or unfavor -able) outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary end point of the Glasgow Outcome Scale?. ### Response: prognosis-based dichotomized (favorable or unfavor -able) outcome.


Instruction: What percentage of surgical patients achieved a favorable outcome compared to 24% in the medical arm?

Output: Twenty-six percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of surgical patients achieved a favorable outcome compared to 24% in the medical arm?. ### Response: Twenty-six percent.


Instruction: What percentage of patients in the medical arm had a favorable outcome compared to 24% in the surgical arm?

Output: Twenty-six percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in the medical arm had a favorable outcome compared to 24% in the surgical arm?. ### Response: Twenty-six percent.


Instruction: What did STICH find no overall statisti-cally significant difference in between treatment groups?

Output: mortality or functional outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did STICH find no overall statisti-cally significant difference in between treatment groups?. ### Response: mortality or functional outcome.


Instruction: How many patients initially assigned to conservative management ultimately underwent surgery?

Output: 26%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients initially assigned to conservative management ultimately underwent surgery?. ### Response: 26%.


Instruction: What was the risk for a poor outcome increased for patients who presented as comatose (GCS score 8)?

Output: ≤8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk for a poor outcome increased for patients who presented as comatose (GCS score 8)?. ### Response: ≤8.


Instruction: What trial was undertaken on the basis of these observations?

Output: STICH II trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What trial was undertaken on the basis of these observations?. ### Response: STICH II trial.


Instruction: Patients with lobar hemorrhages within 1 cm of the cortical surface might be what?

Output: ben-efit from surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with lobar hemorrhages within 1 cm of the cortical surface might be what?. ### Response: ben-efit from surgery.


Instruction: What did the STICH II trial address?

Output: whether early surgery would be beneficial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the STICH II trial address?. ### Response: whether early surgery would be beneficial.


Instruction: What type of lobar hemorrhage is within 1 cm of the cortical surface and without IVH?

Output: superficial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of lobar hemorrhage is within 1 cm of the cortical surface and without IVH?. ### Response: superficial.


Instruction: When were patients admitted to STICH?

Output: within 48 hours of ictus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were patients admitted to STICH?. ### Response: within 48 hours of ictus.


Instruction: How long did it take for a patient to undergo surgery?

Output: Twenty-one percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for a patient to undergo surgery?. ### Response: Twenty-one percent.


Instruction: How many centers in 27 countries participated in the study?

Output: Seventy-eight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many centers in 27 countries participated in the study?. ### Response: Seventy-eight.


Instruction: How many hours of randomization were patients randomized to early surgery plus medical manage-ment or medical management alone?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours of randomization were patients randomized to early surgery plus medical manage-ment or medical management alone?. ### Response: 12.


Instruction: What was the primary outcome?

Output: a prognosis-based dichotomized (favorable or unfavor -able) outcome of the extended Glasgow Outcome Scale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome?. ### Response: a prognosis-based dichotomized (favorable or unfavor -able) outcome of the extended Glasgow Outcome Scale.


Instruction: What was the outcome of the Glasgow Outcome Scale?

Output: prognosis-based dichotomized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the Glasgow Outcome Scale?. ### Response: prognosis-based dichotomized.


Instruction: What percentage of patients in the early surgery group had a favorable outcome compared to 38% in the medical arm?

Output: Forty-one percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in the early surgery group had a favorable outcome compared to 38% in the medical arm?. ### Response: Forty-one percent.


Instruction: What type of analysis showed that patients with poor prognosis were more likely to have a favorable outcome with early surgery?

Output: nonpre-specified subgroup analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of analysis showed that patients with poor prognosis were more likely to have a favorable outcome with early surgery?. ### Response: nonpre-specified subgroup analysis.


Instruction: What was not an advantage to early surgery for patients in the STICH analysis?

Output: good prognosis category

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not an advantage to early surgery for patients in the STICH analysis?. ### Response: good prognosis category.


Instruction: What percentage of patients underwent surgery after initial medical management?

Output: Twenty-one percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients underwent surgery after initial medical management?. ### Response: Twenty-one percent.


Instruction: What was the most common reason for surgery?

Output: patient deterioration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the most common reason for surgery?. ### Response: patient deterioration.


Instruction: Who performed an analysis of the results of STICH II?

Output: The STICH II authors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who performed an analysis of the results of STICH II?. ### Response: The STICH II authors.


Instruction: What is patient deterioration described as?

Output: comatose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is patient deterioration described as?. ### Response: comatose.


Instruction: What did the STICH II authors perform an updated meta-analysis of?

Output: surgical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the STICH II authors perform an updated meta-analysis of?. ### Response: surgical trials.


Instruction: How many patients were included in the update?

Output: 1033

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were included in the update?. ### Response: 1033.


Instruction: Why has early hematoma evacuation not been shown to be beneficial?

Output: high crossover rates of patients to surgical interven-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why has early hematoma evacuation not been shown to be beneficial?. ### Response: high crossover rates of patients to surgical interven-tion.


Instruction: What has not been shown to be beneficial in the 2 largest randomized tri-als?

Output: early hematoma evacuation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been shown to be beneficial in the 2 largest randomized tri-als?. ### Response: early hematoma evacuation.


Instruction: High crossover rates of patients to surgical interven-tion, narrow patient-based inclusion criteria, and the focus of STICH and STICH II leave unclarified?

Output: early surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: High crossover rates of patients to surgical interven-tion, narrow patient-based inclusion criteria, and the focus of STICH and STICH II leave unclarified?. ### Response: early surgery.


Instruction: What is ventricular function suspected to be due to frequent PVCs?

Output: decline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ventricular function suspected to be due to frequent PVCs?. ### Response: decline.


Instruction: What is useful for patients for whom antiarrhythmic medications are ineffective or not tolerated?

Output: catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful for patients for whom antiarrhythmic medications are ineffective or not tolerated?. ### Response: catheter ablation.


Instruction: What is reasonable to reduce recurrent arrhythmias and improve symptoms and LV function?

Output: pharmacological treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to reduce recurrent arrhythmias and improve symptoms and LV function?. ### Response: pharmacological treatment.


Instruction: What may produce a reversible form of LV dysfunction?

Output: Frequent PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may produce a reversible form of LV dysfunction?. ### Response: Frequent PVCs.


Instruction: LV dysfunction has been associated with greater PVC burden (>10% and usually >20%), NSVT, a retrograde P-wave after what?

Output: PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LV dysfunction has been associated with greater PVC burden (>10% and usually >20%), NSVT, a retrograde P-wave after what?. ### Response: PVCs.


Instruction: What are interpolated PVCs?

Output: >30 PVCs per hour

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are interpolated PVCs?. ### Response: >30 PVCs per hour.


Instruction: In a prospective study of catheter ablation for PVC-induced cardiomyopathy, what was com-pletely successful in 80% of patients?

Output: ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a prospective study of catheter ablation for PVC-induced cardiomyopathy, what was com-pletely successful in 80% of patients?. ### Response: ablation.


Instruction: What percentage of patients with depressed ventricular dys-function at baseline had LV func-tion normalized within 6 months?

Output: 82%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with depressed ventricular dys-function at baseline had LV func-tion normalized within 6 months?. ### Response: 82%.


Instruction: What is a reversible cause of LV dysfunction that can be effectively treated with catheter ablation?

Output: frequent PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reversible cause of LV dysfunction that can be effectively treated with catheter ablation?. ### Response: frequent PVCs.


Instruction: What is often difficult to determine if apparent LV dys-function reflects impaired LV function?

Output: inability to accurately assess LV function due to the fre-quent ectopic activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often difficult to determine if apparent LV dys-function reflects impaired LV function?. ### Response: inability to accurately assess LV function due to the fre-quent ectopic activity.


Instruction: What is the cause of LV function?

Output: frequent PVCs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of LV function?. ### Response: frequent PVCs.


Instruction: In patients with a high density of PVCs with normal ventricular function, what has not been established?

Output: optimal treatment and surveillance for prevention and detection of decline in ventricular function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with a high density of PVCs with normal ventricular function, what has not been established?. ### Response: optimal treatment and surveillance for prevention and detection of decline in ventricular function.


Instruction: How many patients were included in a double-blind parallel study?

Output: 30

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were included in a double-blind parallel study?. ### Response: 30.


Instruction: How many patients had ischemic heart disease?

Output: 30

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had ischemic heart disease?. ### Response: 30.


Instruction: How many PVCs per hour did the study compare sotalol to propranolol?

Output: >30

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many PVCs per hour did the study compare sotalol to propranolol?. ### Response: >30.


Instruction: What was the percentage of suppression of PVC in the double-blind parallel study?

Output: sotalol 65%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the percentage of suppression of PVC in the double-blind parallel study?. ### Response: sotalol 65%,.


Instruction: What was the reduction in ventricular couplets for sotalol?

Output: 99%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the reduction in ventricular couplets for sotalol?. ### Response: 99%.


Instruction: What percentage of patients on propranolol had a significant increase in QTc?

Output: 49%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients on propranolol had a significant increase in QTc?. ### Response: 49%.


Instruction: When was the study published?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the study published?. ### Response: April 23, 2023.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive SummaryCirculation. 2019;140:e563–e595. DOI: 10.1161/CIR.0000000000000677 September 10, 2019 e581CLINICAL STATEMENTS AND GUIDELINESS3.2-2. Sanchez A, Bully P, Martinez C, et al. Effectiveness of what in primary care: a review of reviews?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive SummaryCirculation. 2019;140:e563–e595. DOI: 10.1161/CIR.0000000000000677 September 10, 2019 e581CLINICAL STATEMENTS AND GUIDELINESS3.2-2. Sanchez A, Bully P, Martinez C, et al. Effectiveness of what in primary care: a review of reviews?. ### Response: Arnett et al.


Instruction: How many men and women participated in a harmonised meta-analysis of data from more than 1 million people?

Output: 1302–10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many men and women participated in a harmonised meta-analysis of data from more than 1 million people?. ### Response: 1302–10.


Instruction: How many men and women were surveyed in 2016?

Output: more than 1 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many men and women were surveyed in 2016?. ### Response: more than 1 million.


Instruction: What is the name of the journal that published a meta-analysis of prospective cohort studies on walking and primary prevention?

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published a meta-analysis of prospective cohort studies on walking and primary prevention?. ### Response: Lancet.


Instruction: How many people were interviewed in 2016 in relation to physical activity?

Output: more than 1 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were interviewed in 2016 in relation to physical activity?. ### Response: more than 1 million.


Instruction: What is the name of the study that examined physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and stroke events?

Output: Global Burden of Disease Study 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and stroke events?. ### Response: Global Burden of Disease Study 2013.


Instruction: What was the BMJ's 2016 edition of the Global Burden of Disease Study?

Output: 354:i3857

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the BMJ's 2016 edition of the Global Burden of Disease Study?. ### Response: 354:i3857.


Instruction: What does walking reduce the risk of coronary heart disease?

Output: dose-response

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does walking reduce the risk of coronary heart disease?. ### Response: dose-response.


Instruction: What is the name of the meta-analysis that quantifies the dose-response of walking?

Output: meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis that quantifies the dose-response of walking?. ### Response: meta-analysis.


Instruction: When did Eur J Epidemiol. 2009:24:181–92?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Epidemiol. 2009:24:181–92?. ### Response: 2009.


Instruction: What year did Epidemiol. 2009:24:181–92?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Epidemiol. 2009:24:181–92?. ### Response: 2009.


Instruction: What is the name of the systematic review and meta-analysis that quantifies the association between physical activity and cardiovascular disease and diabetes?

Output: Global Burden of Disease Study 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis that quantifies the association between physical activity and cardiovascular disease and diabetes?. ### Response: Global Burden of Disease Study 2013.


Instruction: What does sedentary time have to do with risk for disease incidence, mortality, and hospitalization in adults?

Output: asso-ciation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does sedentary time have to do with risk for disease incidence, mortality, and hospitalization in adults?. ### Response: asso-ciation.


Instruction: What is the name of the systematic review and meta-analysis that examined the relationship between sedence and cardiovascular disease risk?

Output: S3.2-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis that examined the relationship between sedence and cardiovascular disease risk?. ### Response: S3.2-9.


Instruction: When was the Ann Intern Med 162:123-32?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Intern Med 162:123-32?. ### Response: 2015.


Instruction: What did the Women's Health Initiative do?

Output: Relationship of sed-entary behavior and physical activity to incident cardiovascular dis-ease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Women's Health Initiative do?. ### Response: Relationship of sed-entary behavior and physical activity to incident cardiovascular dis-ease.


Instruction: What was the name of the study?

Output: Global Burden of Disease Study 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: Global Burden of Disease Study 2013.


Instruction: When was the J Am Coll Cardiol 61:2346-54?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 61:2346-54?. ### Response: 2013.


Instruction: What is a systematic review and dose response meta-analy-sis?

Output: Global Burden of Disease Study 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and dose response meta-analy-sis?. ### Response: Global Burden of Disease Study 2013.


Instruction: What is an advisory from the American Heart Association?

Output: Guideline on the Primary Prevention of Cardiovascular Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an advisory from the American Heart Association?. ### Response: Guideline on the Primary Prevention of Cardiovascular Disease.


Instruction: Obesity and Being Overweight S4.1-1.

Output: OTHER FACTORS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Obesity and Being Overweight S4.1-1.. ### Response: OTHER FACTORS.


Instruction: What is CARDIOVASCULAR RISK4.1. Obesity and Being Overweight S4.1-1?

Output: OTHER FACTORS AFFECTING CARDIOVASCULAR RISK4.1. Obesity and Being Overweight S4.1-1. LeBlanc EL, Patnode CD, Webber EM, et al. Draft evidence review for weight loss to prevent obesity-related morbidity and mortal-ity in adults: behavioral interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CARDIOVASCULAR RISK4.1. Obesity and Being Overweight S4.1-1?. ### Response: OTHER FACTORS AFFECTING CARDIOVASCULAR RISK4.1. Obesity and Being Overweight S4.1-1. LeBlanc EL, Patnode CD, Webber EM, et al. Draft evidence review for weight loss to prevent obesity-related morbidity and mortal-ity in adults: behavioral interventions.


Instruction: LeBlanc EL, Patnode CD, Webber EM, et al. Draft evidence review for weight loss to prevent what in adults?

Output: obesity-related morbidity and mortal-ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LeBlanc EL, Patnode CD, Webber EM, et al. Draft evidence review for weight loss to prevent what in adults?. ### Response: obesity-related morbidity and mortal-ity.


Instruction: What is enoxaparin used for in the management of high-risk patients with non-ST-elevation acute coronarysyndromes?

Output: themanagement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin used for in the management of high-risk patients with non-ST-elevation acute coronarysyndromes?. ### Response: themanagement.


Instruction: What is the name of the SYNERGY trial?

Output: enoxaparin in themanagement of high-risk patients with non-ST-elevation acute coronarysyndromes: the SYNERGY trial. Am Heart J. 2005;149:S81–90.106. Ferguson JJ, Califf RM, Antman EM, et al. Enoxaparin vs unfractionatedheparin in high-risk patients with non-ST-segment elevation acute coronarysyndromes managed with an intended early invasive strategy: primaryresults of the SYNERGY randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the SYNERGY trial?. ### Response: enoxaparin in themanagement of high-risk patients with non-ST-elevation acute coronarysyndromes: the SYNERGY trial. Am Heart J. 2005;149:S81–90.106. Ferguson JJ, Califf RM, Antman EM, et al. Enoxaparin vs unfractionatedheparin in high-risk patients with non-ST-segment elevation acute coronarysyndromes managed with an intended early invasive strategy: primaryresults of the SYNERGY randomized trial.


Instruction: What strategy was used to manage non-ST-segment elevation acute coronarysyndromes?

Output: early invasive strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What strategy was used to manage non-ST-segment elevation acute coronarysyndromes?. ### Response: early invasive strategy.


Instruction: What was the primary outcome of the SYNERGY randomized trial?

Output: Enoxaparin vs unfractionatedheparin in high-risk patients with non-ST-segment elevation acute coronarysyndromes managed with an intended early invasive strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome of the SYNERGY randomized trial?. ### Response: Enoxaparin vs unfractionatedheparin in high-risk patients with non-ST-segment elevation acute coronarysyndromes managed with an intended early invasive strategy.


Instruction: When was the JAMA's 292:45–54.107 published?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA's 292:45–54.107 published?. ### Response: 2004.


Instruction: Where was the N Engl J Med's 360:2165–75.108 released?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the N Engl J Med's 360:2165–75.108 released?. ### Response: 2009.


Instruction: What is bivalirudin versus heparin used for in patients with acute myocardialinfarction?

Output: fibrinolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is bivalirudin versus heparin used for in patients with acute myocardialinfarction?. ### Response: fibrinolytic therapy.


Instruction: What is the name of the HERO-2 trial?

Output: randomised trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the HERO-2 trial?. ### Response: randomised trial.


Instruction: When was the REPLACE-2 trial conducted?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the REPLACE-2 trial conducted?. ### Response: 2004.


Instruction: What type of blockade is used during percutaneouscoronary revascularization?

Output: glycoprotein IIb/IIIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of blockade is used during percutaneouscoronary revascularization?. ### Response: glycoprotein IIb/IIIa.