Instruction: What is the name of the study that examined dental and cardiac risk factors for infective endocarditis?

Output: a population-based, case-control study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined dental and cardiac risk factors for infective endocarditis?. ### Response: a population-based, case-control study.


Instruction: What is Durack DT's profession?

Output: dentistry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Durack DT's profession?. ### Response: dentistry.


Instruction: Infective endocarditis.

Output: Dental and cardiac risk factorsfor infective endocarditis: a population-based, case-control study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis.. ### Response: Dental and cardiac risk factorsfor infective endocarditis: a population-based, case-control study.


Instruction: What is the N Engl J Med. 1995:332:38–44.4?

Output: Durack DT. Prevention of infective endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 1995:332:38–44.4?. ### Response: Durack DT. Prevention of infective endocarditis.


Instruction: Antibiotics for prevention of what during dentistry:time to scale back?

Output: endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antibiotics for prevention of what during dentistry:time to scale back?. ### Response: endocarditis.


Instruction: What does Lockhart PB, Brennan MT, Fox PC, Norton HJ, Strausbaugh LJ, and Fox PC do?

Output: Prevention ofbacterial endocarditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Lockhart PB, Brennan MT, Fox PC, Norton HJ, Strausbaugh LJ, and Fox PC do?. ### Response: Prevention ofbacterial endocarditis.


Instruction: What is the purpose of antimicrobial prophylaxis for dental procedures?

Output: Decision-making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of antimicrobial prophylaxis for dental procedures?. ### Response: Decision-making.


Instruction: What are the names of the committee on prevention of rheumatic fever and bacterial endocarditis?

Output: Rammelkamp CH Jr, Breese BB, Griffeath HI, Houser HB, Kaplan MH,Kuttner AG, McCarty M, Stollerman GH, Wannamaker LW

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the committee on prevention of rheumatic fever and bacterial endocarditis?. ### Response: Rammelkamp CH Jr, Breese BB, Griffeath HI, Houser HB, Kaplan MH,Kuttner AG, McCarty M, Stollerman GH, Wannamaker LW.


Instruction: What is the acronym for the Committee on Prevention of Rheumatic Fever and Bacterial Endocarditis?

Output: Stollerman GH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Committee on Prevention of Rheumatic Fever and Bacterial Endocarditis?. ### Response: Stollerman GH.


Instruction: What organization is responsible for the prevention of rheumatic fever and bacterial endocarditis through control of streptococcal infections?

Output: AmericanHeart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What organization is responsible for the prevention of rheumatic fever and bacterial endocarditis through control of streptococcal infections?. ### Response: AmericanHeart Association.


Instruction: What year was the Circulation of the American Heart Association published?

Output: 1955

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the Circulation of the American Heart Association published?. ### Response: 1955.


Instruction: What is the acronym for the Committee on Prevention of RheumaticFever and Bacterial Endocarditis, American Heart Association?

Output: Stollerman GH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Committee on Prevention of RheumaticFever and Bacterial Endocarditis, American Heart Association?. ### Response: Stollerman GH.


Instruction: What is Stollerman GH's profession?

Output: Committee on Prevention of RheumaticFever and Bacterial Endocarditis, American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Stollerman GH's profession?. ### Response: Committee on Prevention of RheumaticFever and Bacterial Endocarditis, American Heart Association.


Instruction: What is bacterial endocarditis?

Output: bacterial endo-carditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is bacterial endocarditis?. ### Response: bacterial endo-carditis.


Instruction: What is the acronym for the Committee on Congenital CardiacDefects?

Output: Rheumatic Fever Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Committee on Congenital CardiacDefects?. ### Response: Rheumatic Fever Committee.


Instruction: Who is a member of the Rheumatic Fever Committee?

Output: Rammelkamp CH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the Rheumatic Fever Committee?. ### Response: Rammelkamp CH.


Instruction: Who is a member of the Committee on RheumaticFever and Bacterial Endocarditis, American Heart Association?

Output: Kaplan EL, Anthony BF, Bisno A, Durack D, Houser H, Millard HD, SanfordJ, Shulman ST, Stollerman M, Taranta A, Wenger N

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the Committee on RheumaticFever and Bacterial Endocarditis, American Heart Association?. ### Response: Kaplan EL, Anthony BF, Bisno A, Durack D, Houser H, Millard HD, SanfordJ, Shulman ST, Stollerman M, Taranta A, Wenger N.


Instruction: What is the name of the organization that is responsible for the prevention of bacterial endocardiitis?

Output: American Heart Asso-ciation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that is responsible for the prevention of bacterial endocardiitis?. ### Response: American Heart Asso-ciation.


Instruction: When was the Circulation of 1977 published?

Output: 1965

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation of 1977 published?. ### Response: 1965.


Instruction: What did Bozkurt and colleagues report on December 6, 2016?

Output: diverging from those without the syndrome at ≈10 years of follow-up, suggesting that long-term follow-up may be necessary to truly estimate the impact of the metabolic syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Bozkurt and colleagues report on December 6, 2016?. ### Response: diverging from those without the syndrome at ≈10 years of follow-up, suggesting that long-term follow-up may be necessary to truly estimate the impact of the metabolic syndrome.


Instruction: What is the risk of HF with the metabolic syn-drome consistently demonstrated in other diseases?

Output: increased risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of HF with the metabolic syn-drome consistently demonstrated in other diseases?. ### Response: increased risk.


Instruction: What has consistently been demonstrated in other populations?

Output: The increased risk of HF with the metabolic syn-drome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has consistently been demonstrated in other populations?. ### Response: The increased risk of HF with the metabolic syn-drome.


Instruction: What do obesity, hypertension, and an increased fasting glucose most strongly predict?

Output: incident HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do obesity, hypertension, and an increased fasting glucose most strongly predict?. ### Response: incident HF.


Instruction: What was the most strongly predicted incident HF?

Output: obesity, hypertension, and an increased fasting glucose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the most strongly predicted incident HF?. ### Response: obesity, hypertension, and an increased fasting glucose.


Instruction: What does the metabolic syndrome not predict better than its individual components?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the metabolic syndrome not predict better than its individual components?. ### Response: HF.


Instruction: What did the WHO, National Cholesterol Education Program, International Diabetes Federation, and AHA/National Heart, Lung, and Blood Institute define as predictive of incident HF?

Output: -6, fibrinogen, and microalbuminuria levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the WHO, National Cholesterol Education Program, International Diabetes Federation, and AHA/National Heart, Lung, and Blood Institute define as predictive of incident HF?. ### Response: -6, fibrinogen, and microalbuminuria levels.


Instruction: What did MESA199 and this study demonstrate?

Output: the metabolic syndrome predicts HF independently of MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did MESA199 and this study demonstrate?. ### Response: the metabolic syndrome predicts HF independently of MI.


Instruction: What predicts HF independently of MI?

Output: metabolic syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts HF independently of MI?. ### Response: metabolic syndrome.


Instruction: What suggests that the metabolic syndrome is also associated with nonischemic HF?

Output: MESA199 and this study demonstrated that the metabolic syndrome predicts HF independently of MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What suggests that the metabolic syndrome is also associated with nonischemic HF?. ### Response: MESA199 and this study demonstrated that the metabolic syndrome predicts HF independently of MI.


Instruction: What were significant predictors of incident HF in CHS?

Output: obesity, hypertension, and an increased fasting glucose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were significant predictors of incident HF in CHS?. ### Response: obesity, hypertension, and an increased fasting glucose.


Instruction: What was additive information when combined with the metabolic syndrome in predicting the development of HF?

Output: a C-reactive protein level ≥3 mg/L and interleukin-6 level ≥2.21 pg/mL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was additive information when combined with the metabolic syndrome in predicting the development of HF?. ### Response: a C-reactive protein level ≥3 mg/L and interleukin-6 level ≥2.21 pg/mL.


Instruction: What was an independent risk factor for the development of HF?

Output: obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was an independent risk factor for the development of HF?. ### Response: obesity.


Instruction: What was the result of adding interleukin-6 or C-reactive protein to MESA?

Output: attenuated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of adding interleukin-6 or C-reactive protein to MESA?. ### Response: attenuated.


Instruction: What may be partially mediated through inflammatory pathways?

Output: the effects of obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be partially mediated through inflammatory pathways?. ### Response: the effects of obesity.


Instruction: What is the prevalence and effects of the metabolic syndrome in the established HF population less well known?

Output: 199role of the Metabolic Syndrome in p atients With Established HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence and effects of the metabolic syndrome in the established HF population less well known?. ### Response: 199role of the Metabolic Syndrome in p atients With Established HF.


Instruction: What is metabolic syndrome in the established HF population less well studied?

Output: prevalence and effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is metabolic syndrome in the established HF population less well studied?. ### Response: prevalence and effects.


Instruction: What is an independent risk factor for the development of HF?

Output: obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an independent risk factor for the development of HF?. ### Response: obesity.


Instruction: The prevalence of metabolic syndrome is higher in what population than in the general adult population?

Output: HF population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The prevalence of metabolic syndrome is higher in what population than in the general adult population?. ### Response: HF population.


Instruction: How many studies were done in the United States?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were done in the United States?. ### Response: 2.


Instruction: What was the prevalence of HFrEF in the 2 studies?

Output: 297

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the prevalence of HFrEF in the 2 studies?. ### Response: 297.


Instruction: What is the name of the 2018 ACHD Guideline?

Output: Stout et al 2018 ACHD GuidelineTable 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2018 ACHD Guideline?. ### Response: Stout et al 2018 ACHD GuidelineTable 23.


Instruction: What is another name for Valvular PS: Routine Follow-Up and Testing Intervals?

Output: pulmonary stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Valvular PS: Routine Follow-Up and Testing Intervals?. ### Response: pulmonary stenosis.


Instruction: How long is the walk test?

Output: 6-minute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the walk test?. ### Response: 6-minute.


Instruction: What is the AP classification system for ACHD?

Output: 6-minute walk test or CPET

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AP classification system for ACHD?. ### Response: 6-minute walk test or CPET.


Instruction: What indicates adult congenital heart disease?

Output: ACHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates adult congenital heart disease?. ### Response: ACHD.


Instruction: What does CPET stand for?

Output: cardiopulmonary exercise test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CPET stand for?. ### Response: cardiopulmonary exercise test.


Instruction: What indicates CPET?

Output: cardiopulmonary exercise test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates CPET?. ### Response: cardiopulmonary exercise test.


Instruction: PR stands for what?

Output: pulmonary regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PR stands for what?. ### Response: pulmonary regurgitation.


Instruction: What does aNOAC facilitate treatment without?

Output: heparin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does aNOAC facilitate treatment without?. ### Response: heparin therapy.


Instruction: What criteria are suitable for treatment of acute PE out of the hospital?

Output: :(1) clinically stable with good cardiopulmonary reserve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria are suitable for treatment of acute PE out of the hospital?. ### Response: :(1) clinically stable with good cardiopulmonary reserve.


Instruction: What does PE out of the hospital have?

Output: clinically stable with good cardiopulmonary reserve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PE out of the hospital have?. ### Response: clinically stable with good cardiopulmonary reserve.


Instruction: What is expected to be compliant with?

Output: treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is expected to be compliant with?. ### Response: treatment.


Instruction: Who feels well enough to be treated at home?

Output: the patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who feels well enough to be treated at home?. ### Response: the patient.


Instruction: What can clinical decision rules help to identify low-risk patients who aresuitable for treatment at home?

Output: Pulmonary Embolism Severity Index

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can clinical decision rules help to identify low-risk patients who aresuitable for treatment at home?. ### Response: Pulmonary Embolism Severity Index.


Instruction: What does not require patients to have a prede finedscore to be considered fortreatment at home?

Output: clinical prediction rules

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not require patients to have a prede finedscore to be considered fortreatment at home?. ### Response: clinical prediction rules.


Instruction: What is a low-risk PESI score?

Output: <85

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a low-risk PESI score?. ### Response: <85.


Instruction: What should discourage treatment out of the hospital?

Output: the presence of right ventriculardysfunction or increased cardiac biomarker levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should discourage treatment out of the hospital?. ### Response: the presence of right ventriculardysfunction or increased cardiac biomarker levels.


Instruction: The quality of the evidence for treatment of acute PE at home remains moderate because of what?

Output: marked imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The quality of the evidence for treatment of acute PE at home remains moderate because of what?. ### Response: marked imprecision.


Instruction: How can appropriately selected patients be treated at home rather than be discharged early?

Output: entirely at home

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can appropriately selected patients be treated at home rather than be discharged early?. ### Response: entirely at home.


Instruction: In patients with low-risk PE and whose homecircumstances are adequate, we suggest treatment athome or early discharge over what?

Output: standard discharge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with low-risk PE and whose homecircumstances are adequate, we suggest treatment athome or early discharge over what?. ### Response: standard discharge.


Instruction: What is grade 2B?

Output: early discharge over standard discharge

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is grade 2B?. ### Response: early discharge over standard discharge.


Instruction: What does systemic thrombolytic therapy do for PE?

Output: accelerates resolution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does systemic thrombolytic therapy do for PE?. ### Response: accelerates resolution.


Instruction: What does thrombolytic therapy increase in patients with acute PE?

Output: bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does thrombolytic therapy increase in patients with acute PE?. ### Response: bleeding.


Instruction: What is the net mortality bene fit of throbolytictherapy in patients?

Output: <70,000/mm3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the net mortality bene fit of throbolytictherapy in patients?. ### Response: <70,000/mm3.


Instruction: Who has the highest risk of dying from PE and the lowest?

Output: Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has the highest risk of dying from PE and the lowest?. ### Response: Patients.


Instruction: What is the highest risk of dying from PE and lowest risk of bleeding from thrombolytic therapy?

Output: Patients with thehighest risk of dying from PE and the lowest risk ofbleeding obtain the greatest net bene ﬁt fromthrombolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the highest risk of dying from PE and lowest risk of bleeding from thrombolytic therapy?. ### Response: Patients with thehighest risk of dying from PE and the lowest risk ofbleeding obtain the greatest net bene ﬁt fromthrombolytic therapy.


Instruction: Patients with the lowestrisk of dying and the highest chance of bleeding get the least net bene fit from what?

Output: thrombolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with the lowestrisk of dying and the highest chance of bleeding get the least net bene fit from what?. ### Response: thrombolytic therapy.


Instruction: What is evidence for the Use of Thrombolytic Therapy?

Output: low-quality evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evidence for the Use of Thrombolytic Therapy?. ### Response: low-quality evidence.


Instruction: How many patients with acute PE had been randomized to receive thrombolytic therapy or anticoagulant therapy alone?

Output: 800

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with acute PE had been randomized to receive thrombolytic therapy or anticoagulant therapy alone?. ### Response: 800.


Instruction: Where is the Walter Reed National Military Medical Center located?

Output: Bethesda, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Walter Reed National Military Medical Center located?. ### Response: Bethesda, MD.


Instruction: How many people were in the patient focus group?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were in the patient focus group?. ### Response: three.


Instruction: How many people were included in the patient focus group?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were included in the patient focus group?. ### Response: three.


Instruction: What does the Work Group acknowledge is not representative of all VA and DoD patients?

Output: patient focus group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Work Group acknowledge is not representative of all VA and DoD patients?. ### Response: patient focus group.


Instruction: What are the key conc epts of the focus group?

Output: patient focus group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the key conc epts of the focus group?. ### Response: patient focus group.


Instruction: What should be analyzed in advance?

Output: CLINICAL STATEMENTS  AND GUIDELINES implementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be analyzed in advance?. ### Response: CLINICAL STATEMENTS  AND GUIDELINES implementation.


Instruction: How should implementation strategies be tailored to the setting and target audience?

Output: implementation should be analyzed in advance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should implementation strategies be tailored to the setting and target audience?. ### Response: implementation should be analyzed in advance.


Instruction: What may patients who participate in shared decision-making have better health outcomes, better health-care experiences, and lower costs?

Output: S6-7,S6-8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients who participate in shared decision-making have better health outcomes, better health-care experiences, and lower costs?. ### Response: S6-7,S6-8.


Instruction: What does the patient participate with the clinician in deciding?

Output: lifestyle modifications, medica-tion treatment, and goals of therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the patient participate with the clinician in deciding?. ### Response: lifestyle modifications, medica-tion treatment, and goals of therapy.


Instruction: What should the patient verbalize for making lifestyle changes and taking medications?

Output: values, attitudes, abilities, concerns, and personal goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the patient verbalize for making lifestyle changes and taking medications?. ### Response: values, attitudes, abilities, concerns, and personal goals.


Instruction: Who should explain the patient's risk of clinical ASCVD and how the treatment recommendations reduce it?

Output: The clinician

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should explain the patient's risk of clinical ASCVD and how the treatment recommendations reduce it?. ### Response: The clinician.


Instruction: What are personal goals for making lifestyle changes and taking medications?

Output: concerns about cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are personal goals for making lifestyle changes and taking medications?. ### Response: concerns about cost.


Instruction: What may the clinician use to facilitate shared decision-making with the patient?

Output: tools and techniques

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may the clinician use to facilitate shared decision-making with the patient?. ### Response: tools and techniques.


Instruction: The clinician should use tools and techniques to support what?

Output: shared decision-making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The clinician should use tools and techniques to support what?. ### Response: shared decision-making.


Instruction: What type of decision aids can help a patient be more knowledgeable?

Output: decision coaching

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of decision aids can help a patient be more knowledgeable?. ### Response: decision coaching.


Instruction: What type or type of question prompt lists can help the patient become more knowledgeable about treatment?

Output: ivational interviewing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type or type of question prompt lists can help the patient become more knowledgeable about treatment?. ### Response: ivational interviewing.


Instruction: What type of interviewing may also promote patient knowledge and satisfaction?

Output: ivational

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of interviewing may also promote patient knowledge and satisfaction?. ### Response: ivational.


Instruction: What is one of the economic value considerations?

Output: cost-effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the economic value considerations?. ### Response: cost-effectiveness.


Instruction: What does PCSK9 inhibitors reduce when combined with other LDL-lowering drugs?

Output: LDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PCSK9 inhibitors reduce when combined with other LDL-lowering drugs?. ### Response: LDL-C.


Instruction: What does economic value consider in making recommendations?

Output: principles established by an expert group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does economic value consider in making recommendations?. ### Response: principles established by an expert group.


Instruction: What did PCSK9 reduce in 2 RCTs of high-risk, secondary-prevention patients with ASCVD?

Output: composite car -diovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did PCSK9 reduce in 2 RCTs of high-risk, secondary-prevention patients with ASCVD?. ### Response: composite car -diovascular events.


Instruction: What has been assessed by using simulation models?

Output: The cost-effectiveness and economic value of PCSK9 inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been assessed by using simulation models?. ### Response: The cost-effectiveness and economic value of PCSK9 inhibitors.


Instruction: How are the published models based?

Output: different sets of assumptions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the published models based?. ### Response: different sets of assumptions.


Instruction: What are the published models based on?

Output: different sets of assumptions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the published models based on?. ### Response: different sets of assumptions.


Instruction: What do the incremental cost-effectiveness ratiosS7.1-3 range from?

Output: $141 700 to $450 000 per quality-adjusted life-year (QALY) added

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the incremental cost-effectiveness ratiosS7.1-3 range from?. ### Response: $141 700 to $450 000 per quality-adjusted life-year (QALY) added.


Instruction: How much do PCSK9 inhibitors cost per quality-adjusted life-year?

Output: $141 700 to $450 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much do PCSK9 inhibitors cost per quality-adjusted life-year?. ### Response: $141 700 to $450 000.


Instruction: What does none of the published models report?

Output: good value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does none of the published models report?. ### Response: good value.


Instruction: What does virtually all models indicate?

Output: “low value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does virtually all models indicate?. ### Response: “low value.


Instruction: What is hyper tension in adults: diagnosis and manag emen t NICE guideline Published: 28 August 2019 www.nice.or g.uk/guidance/ng136  NICE 2023 All right s reserved.

Output: Hyper tension in adul ts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hyper tension in adults: diagnosis and manag emen t NICE guideline Published: 28 August 2019 www.nice.or g.uk/guidance/ng136  NICE 2023 All right s reserved.. ### Response: Hyper tension in adul ts.


Instruction: Who wrote the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the name of the 2021 guideline?

Output: ACC/AHA Guideline for the Management of Valvular Heart Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2021 guideline?. ### Response: ACC/AHA Guideline for the Management of Valvular Heart Disease.


Instruction: Who is the Task Force on Practice Guidelines?

Output: Cardiology Foundation/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Task Force on Practice Guidelines?. ### Response: Cardiology Foundation/American Heart Association.


Instruction: Which drug is used to reduce secondary mitral re-gurgitation?

Output: Sacubitril/valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug is used to reduce secondary mitral re-gurgitation?. ### Response: Sacubitril/valsartan.


Instruction: What drug is used to reduce secondary mitral re-gurgitation?

Output: Sacubitril/valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used to reduce secondary mitral re-gurgitation?. ### Response: Sacubitril/valsartan.


Instruction: What is sacubitril/valsartan used for?

Output: reduce secondary mitral re-gurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is sacubitril/valsartan used for?. ### Response: reduce secondary mitral re-gurgitation.


Instruction: In what year did Abraham WT, Fisher WG, Smith AL, et al. develop cardiac resynchronization?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Abraham WT, Fisher WG, Smith AL, et al. develop cardiac resynchronization?. ### Response: 2002.


Instruction: What is the name of the procedure used to repair mitral valves in heart failure patients?

Output: Transcatheter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used to repair mitral valves in heart failure patients?. ### Response: Transcatheter.


Instruction: What type of repair is used in patients with heart failure?

Output: Transcatheter mitral-valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of repair is used in patients with heart failure?. ### Response: Transcatheter mitral-valve.


Instruction: In what year did Stone GW, Lindenfeld J, Abraham WT, et al. have surgery?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Stone GW, Lindenfeld J, Abraham WT, et al. have surgery?. ### Response: 2006.


Instruction: What is the name of the procedure used for secondary mitral regurgitation?

Output: Percutaneous repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used for secondary mitral regurgitation?. ### Response: Percutaneous repair.


Instruction: How long does it take to repair the mitral valve after a MitraClip?

Output: One-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to repair the mitral valve after a MitraClip?. ### Response: One-year.


Instruction: What is one of the outcomes of the Mitraclip procedure?

Output: reverse remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the outcomes of the Mitraclip procedure?. ### Response: reverse remodeling.


Instruction: What is a new conceptual framework that recon-ciles the results of MITRA-FR and COAPT?

Output: Proportionate and disproportionate functional mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new conceptual framework that recon-ciles the results of MITRA-FR and COAPT?. ### Response: Proportionate and disproportionate functional mitral regurgitation.


Instruction: What framework recon-ciles the results of the MITRA-FR and COAPT trials?

Output: Proportionate and disproportionate functional mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What framework recon-ciles the results of the MITRA-FR and COAPT trials?. ### Response: Proportionate and disproportionate functional mitral regurgitation.


Instruction: What is the JACC Cardiovasc Imag-ing. 2019;12:353–62?

Output: Proportionate and disproportionate functional mitral regurgitation: a new conceptual framework that recon-ciles the results of the MITRA-FR and COAPT trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JACC Cardiovasc Imag-ing. 2019;12:353–62?. ### Response: Proportionate and disproportionate functional mitral regurgitation: a new conceptual framework that recon-ciles the results of the MITRA-FR and COAPT trials.


Instruction: How many trials did Nishimura RA, Bonow RO, and Alipour have?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many trials did Nishimura RA, Bonow RO, and Alipour have?. ### Response: two.


Instruction: What is the survival rate of transcatheter mitral valve repair compared with surgical and conservative treatment in high-surgical-risk patients?

Output: 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the survival rate of transcatheter mitral valve repair compared with surgical and conservative treatment in high-surgical-risk patients?. ### Response: 7.


Instruction: What does MitraClip improve in nonresponders to cardiac resynchronization therapy?

Output: symptoms and promotes reverse remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MitraClip improve in nonresponders to cardiac resynchronization therapy?. ### Response: symptoms and promotes reverse remodeling.


Instruction: What improves symptoms and promotes reverse remodeling?

Output: cardiac resynchronization therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What improves symptoms and promotes reverse remodeling?. ### Response: cardiac resynchronization therapy.


Instruction: What does MitraClip promote?

Output: reverse remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MitraClip promote?. ### Response: reverse remodeling.


Instruction: When did the J Am Coll Cardiol. 201158:2183-9.

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol. 201158:2183-9.. ### Response: 2011.


Instruction: What is the effect of mitral regurgitation re-pair on survival?

Output: reverse left ven-tricular remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of mitral regurgitation re-pair on survival?. ### Response: reverse left ven-tricular remodeling.


Instruction: What is the name of the study that investigated the effect of no-to-moderate mitral regurgitation on late results after isolated coronary artery bypass grafting in patients with ischemic cardiomyopathy?

Output: COAPT trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effect of no-to-moderate mitral regurgitation on late results after isolated coronary artery bypass grafting in patients with ischemic cardiomyopathy?. ### Response: COAPT trial.


Instruction: What was the name given to the study in 2012?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name given to the study in 2012?. ### Response: Circulation.


Instruction: What type of annuloplasty results in reverse left ven-tricular remodeling?

Output: Restrictive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of annuloplasty results in reverse left ven-tricular remodeling?. ### Response: Restrictive.


Instruction: What is the effect of restrictive annuloplasty and coronary revascularization in ischemic mitral regurgitation?

Output: reverse left ven-tricular remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of restrictive annuloplasty and coronary revascularization in ischemic mitral regurgitation?. ### Response: reverse left ven-tricular remodeling.


Instruction: When was Circulation.110:II103-8 published?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation.110:II103-8 published?. ### Response: 2004.


Instruction: How many large observationalstudies of familial aneurysms suggest that screening may be cost-effective in preventing aSAH and improving quality of life?

Output: Two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many large observationalstudies of familial aneurysms suggest that screening may be cost-effective in preventing aSAH and improving quality of life?. ### Response: Two.


Instruction: What is it less clear whetherpatients who underwent treatment for a previous aSAHrequire ongoing screening?

Output: Smaller studies have suggestedthat screening of those with 1 first-degree relative with aSAHmay be justified as well, but it is far less clear whetherpatients who underwent treatment for a previous aSAHrequire ongoing screening.51,52

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is it less clear whetherpatients who underwent treatment for a previous aSAHrequire ongoing screening?. ### Response: Smaller studies have suggestedthat screening of those with 1 first-degree relative with aSAHmay be justified as well, but it is far less clear whetherpatients who underwent treatment for a previous aSAHrequire ongoing screening.51,52.


Instruction: What was predicted by incomplete obliteration of the aneurysm in the CARAT study?

Output: recurrent aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was predicted by incomplete obliteration of the aneurysm in the CARAT study?. ### Response: recurrent aSAH.


Instruction: How long do patients with adequatelyobliterated aneurysms have a low risk of recurrentaSAH?

Output: 5 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long do patients with adequatelyobliterated aneurysms have a low risk of recurrentaSAH?. ### Response: 5 years.


Instruction: How long does coiled aneu-rysm require retreatment?

Output: 5 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does coiled aneu-rysm require retreatment?. ### Response: 5 years.


Instruction: What may not be cost-effective or improve quality of life in unselected patients?

Output: Repeated noninvasive screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not be cost-effective or improve quality of life in unselected patients?. ### Response: Repeated noninvasive screening.


Instruction: What is a risk factor for and prevention of aSAH?

Output: Treatment of high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for and prevention of aSAH?. ### Response: Treatment of high.


Instruction: What is recommended to prevent ische-mic stroke?

Output: Treatment of high blood pressure with antihyper-tensive medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to prevent ische-mic stroke?. ### Response: Treatment of high blood pressure with antihyper-tensive medication.


Instruction: What should be avoided to reduce the risk of aSAH?

Output: Tobacco use and alcohol misuse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be avoided to reduce the risk of aSAH?. ### Response: Tobacco use and alcohol misuse.


Instruction: What is the Class I; Level of Evidence B?

Output: Tobacco use and alcohol misuse should be avoided toreduce the risk of aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class I; Level of Evidence B?. ### Response: Tobacco use and alcohol misuse should be avoided toreduce the risk of aSAH.


Instruction: What is the weight of evidence or opinion infavor of the treatment?

Output: Class IIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the weight of evidence or opinion infavor of the treatment?. ### Response: Class IIa.


Instruction: What is a condition for which there is evidence for and/or general agreement that the procedure or treatment is useful andeffective?

Output: Class I Conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a condition for which there is evidence for and/or general agreement that the procedure or treatment is useful andeffective?. ### Response: Class I Conditions.


Instruction: What is the weight of evidence or opinion in favor of the procedure or treatment?

Output: Class IIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the weight of evidence or opinion in favor of the procedure or treatment?. ### Response: Class IIa.


Instruction: What is less well established by evidence or opinions?

Output: Usefulness/efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less well established by evidence or opinions?. ### Response: Usefulness/efficacy.


Instruction: What kind of recommendations are derived from multiple randomizedclinical trials or meta-analyses?

Output: Therapeutic recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What kind of recommendations are derived from multiple randomizedclinical trials or meta-analyses?. ### Response: Therapeutic recommendations.


Instruction: What type of recommendations do experts, casestudies or standard of care have?

Output: Diagnostic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of recommendations do experts, casestudies or standard of care have?. ### Response: Diagnostic.


Instruction: What type of data derived from multiple prospectivecohort studies using a reference standard applied by a masked evaluatorLevel of Evidence C Consensus opinion of experts1714 Stroke June 2012Downloaded from what site?

Output: Evidence A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of data derived from multiple prospectivecohort studies using a reference standard applied by a masked evaluatorLevel of Evidence C Consensus opinion of experts1714 Stroke June 2012Downloaded from what site?. ### Response: Evidence A.


Instruction: Evidence C Consensus opinion of experts1714 Stroke June 2012Downloaded from http://ahajournals.org by on what date?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence C Consensus opinion of experts1714 Stroke June 2012Downloaded from http://ahajournals.org by on what date?. ### Response: April 28, 2023.


Instruction: What is the name of the study that was conducted on December 6, 2016?

Output: Management of Comorbidities in Chronic Heart FailureCirculation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that was conducted on December 6, 2016?. ### Response: Management of Comorbidities in Chronic Heart FailureCirculation.


Instruction: What did the long-term follow-up of the DCCT and UKPDS cohorts suggest about A1c targets?

Output: treat-ment to A1c targets below or near 7% in the years soon after the diagnosis of diabetes is associated with long-term reduction in risk of macrovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the long-term follow-up of the DCCT and UKPDS cohorts suggest about A1c targets?. ### Response: treat-ment to A1c targets below or near 7% in the years soon after the diagnosis of diabetes is associated with long-term reduction in risk of macrovascular disease.


Instruction: What is associated with a long-term reduction in risk of macrovascular disease?

Output: treat-ment to A1c targets below or near 7% in the years soon after the diagnosis of diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with a long-term reduction in risk of macrovascular disease?. ### Response: treat-ment to A1c targets below or near 7% in the years soon after the diagnosis of diabetes.


Instruction: What is the general goal of 7%?

Output: <7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the general goal of 7%?. ### Response: <7%.


Instruction: What is the IIb recommendation?

Output: Level of Evidence A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the IIb recommendation?. ### Response: Level of Evidence A.


Instruction: For some patients, individualized glycemic tar-gets other than the above general goal may be appropriate?

Output: less stringent goals of HbA1c <7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For some patients, individualized glycemic tar-gets other than the above general goal may be appropriate?. ### Response: less stringent goals of HbA1c <7%.


Instruction: Subgroup analyses of clinical trials such as the DCCT and UKPDS and the micro-vascular evidence from the ADVANCE trial suggest what?

Output: a small but incremental benefit in microvascular outcomes with A1c values closer to normal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Subgroup analyses of clinical trials such as the DCCT and UKPDS and the micro-vascular evidence from the ADVANCE trial suggest what?. ### Response: a small but incremental benefit in microvascular outcomes with A1c values closer to normal.


Instruction: What does the ADVANCE trial suggest a small but incremental benefit in microvascular outcomes with A1c values closer to normal?

Output: Subgroup analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ADVANCE trial suggest a small but incremental benefit in microvascular outcomes with A1c values closer to normal?. ### Response: Subgroup analyses.


Instruction: What might providers rea-sonably suggest for selected individual patients?

Output: even lower A1c goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might providers rea-sonably suggest for selected individual patients?. ### Response: even lower A1c goals.


Instruction: If it can be achieved without significant hypoglycemia or other adverse effects, what might be suggested?

Output: lower A1c goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If it can be achieved without significant hypoglycemia or other adverse effects, what might be suggested?. ### Response: lower A1c goals.


Instruction: What is the B-level recommendation for diabetes?

Output: ADA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the B-level recommendation for diabetes?. ### Response: ADA.


Instruction: What is Class IIa rec-ommendation?

Output: Level of Evidence C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Class IIa rec-ommendation?. ### Response: Level of Evidence C.


Instruction: How are A1c goals different from general goals?

Output: if it can be achieved without significant hypoglycemia or other adverse effects of treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are A1c goals different from general goals?. ### Response: if it can be achieved without significant hypoglycemia or other adverse effects of treatment.


Instruction: What is the general goal of 7% for A1c?

Output: <7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the general goal of 7% for A1c?. ### Response: <7%.


Instruction: What may be appropri-ate for patients with a history of severe hypoglycemia, limited life expectancy, advanced microvascular or macrovascu-lar complications, or those with long-standing diabetes?

Output: individualized glycemic tar-gets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be appropri-ate for patients with a history of severe hypoglycemia, limited life expectancy, advanced microvascular or macrovascu-lar complications, or those with long-standing diabetes?. ### Response: individualized glycemic tar-gets.


Instruction: What does ADA stand for?

Output: C-level recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ADA stand for?. ### Response: C-level recommendation.


Instruction: What is ACC/AHA's recommendation for glycemic control?

Output: Class IIb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACC/AHA's recommendation for glycemic control?. ### Response: Class IIb.


Instruction: What does tight glycemic control improve in patients with HF?

Output: out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does tight glycemic control improve in patients with HF?. ### Response: out-comes.


Instruction: What may be confounded by baseline comorbid conditions?

Output: lower glycemic HbA1c levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be confounded by baseline comorbid conditions?. ### Response: lower glycemic HbA1c levels.


Instruction: Where are prospective data available?

Output: ACCORD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are prospective data available?. ### Response: ACCORD.


Instruction: There is not enough evidence to sug-gest that HbA1c levels are good or bad for HF patients?

Output: There is not enough evidence to sug-gest that HbA1c targets should be dif-ferent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is not enough evidence to sug-gest that HbA1c levels are good or bad for HF patients?. ### Response: There is not enough evidence to sug-gest that HbA1c targets should be dif-ferent.


Instruction: What is not enough evidence to suggest that HbA1c targets should be dif-ferent from the targets described above?

Output: Prospective data are available only from ACCORD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not enough evidence to suggest that HbA1c targets should be dif-ferent from the targets described above?. ### Response: Prospective data are available only from ACCORD.


Instruction: What may be more appropriate for patients with HF?

Output: less stringent goals of HbA1c <7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be more appropriate for patients with HF?. ### Response: less stringent goals of HbA1c <7%.


Instruction: What are conditions that are difficult to control?

Output: hypoglycemia, adverse effects of medications, variable blood glucose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are conditions that are difficult to control?. ### Response: hypoglycemia, adverse effects of medications, variable blood glucose.


Instruction: What is the name of the study that included a subset of the UKPDS 34 study?

Output: Antihyperglycemic Medications in p atients With HF and Diabetes MellitusMetforminRandomized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that included a subset of the UKPDS 34 study?. ### Response: Antihyperglycemic Medications in p atients With HF and Diabetes MellitusMetforminRandomized.


Instruction: How many diabetic patients received background insulin ther-apy?

Output: 390

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many diabetic patients received background insulin ther-apy?. ### Response: 390.


Instruction: How many of the 390 patients receiving background insulin have demonstrated metformin-associated what?

Output: 188

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the 390 patients receiving background insulin have demonstrated metformin-associated what?. ### Response: 188.


Instruction: What year did Cardiol Intv publish a study on the effectiveness of percutaneouscoronary intervention?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Cardiol Intv publish a study on the effectiveness of percutaneouscoronary intervention?. ### Response: 2008.


Instruction: What year was the JAMA published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the JAMA published?. ### Response: 2011.


Instruction: How many pages were in the Journal of Cardiology in 2008?

Output: 51:716–23.428

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages were in the Journal of Cardiology in 2008?. ### Response: 51:716–23.428.


Instruction: Whose judgments of survival after medical management and mortality risk reduction are based on revascularization procedures?

Output: Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Whose judgments of survival after medical management and mortality risk reduction are based on revascularization procedures?. ### Response: Physicians.


Instruction: What is the name of the disease that affects a person with coronary artery disease?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects a person with coronary artery disease?. ### Response: hypertension.


Instruction: When was the last time a patient underwent elective percutaneous coronaryrevascularization?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a patient underwent elective percutaneous coronaryrevascularization?. ### Response: 2011.


Instruction: What was the title of the study that examined the perceptions of benefit andrisk of patients undergoing first-time elective revascularisation?

Output: Appropriateness of percutaneouscoronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the study that examined the perceptions of benefit andrisk of patients undergoing first-time elective revascularisation?. ### Response: Appropriateness of percutaneouscoronary intervention.


Instruction: How did Lin GA, Dudley RA, Redberg RF evaluate the use of percutaneouscoronary interventions?

Output: Appropriateness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Lin GA, Dudley RA, Redberg RF evaluate the use of percutaneouscoronary interventions?. ### Response: Appropriateness.


Instruction: What is a risk factor for stable coronary artery disease?

Output: Regional variation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for stable coronary artery disease?. ### Response: Regional variation.


Instruction: What is an example of a regional variation in cardiaccatheterization appropriateness and baseline risk after acute myocardialinfarction?

Output: Ko DT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a regional variation in cardiaccatheterization appropriateness and baseline risk after acute myocardialinfarction?. ### Response: Ko DT.


Instruction: What is a topic brief by the DartmouthAtlas of Health Care Project?

Output: Health care spending

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a topic brief by the DartmouthAtlas of Health Care Project?. ### Response: Health care spending.


Instruction: How many patients allege unnecessary heart surgery?

Output: Dozens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients allege unnecessary heart surgery?. ### Response: Dozens.


Instruction: What year did Tex Heart Inst J issue 35:6–15.431?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Tex Heart Inst J issue 35:6–15.431?. ### Response: 2008.


Instruction: What is the name of the committee that reviews diseases of the heart and uses coronary revascularization in medicarebeneficiaries?

Output: The Criteria Committee of the New

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that reviews diseases of the heart and uses coronary revascularization in medicarebeneficiaries?. ### Response: The Criteria Committee of the New.


Instruction: What is the New York Heart Association I. Diseases of the heart and blood vessels: nomenclature and critera for diagnosis.6th ed. Boston: Little, Brown; 1964.434. What is Spertus JA, Eagle KA, Krumholz HM, et al.?

Output: The Criteria Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the New York Heart Association I. Diseases of the heart and blood vessels: nomenclature and critera for diagnosis.6th ed. Boston: Little, Brown; 1964.434. What is Spertus JA, Eagle KA, Krumholz HM, et al.?. ### Response: The Criteria Committee.


Instruction: What are performance measures for quantifying?

Output: quality of cardiovascular care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are performance measures for quantifying?. ### Response: quality of cardiovascular care.


Instruction: What is the J Am Coll Cardiol. 2005:45:1147–56.435?

Output: performance measures for quantifying thequality of cardiovascular care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2005:45:1147–56.435?. ### Response: performance measures for quantifying thequality of cardiovascular care.


Instruction: What is the name of the Task Force on Performan ceMeasures and the American Medical Association-Physician C on-sortium for Performance Improvement?

Output: American College of Cardiolog y Foun-dation/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Performan ceMeasures and the American Medical Association-Physician C on-sortium for Performance Improvement?. ### Response: American College of Cardiolog y Foun-dation/American Heart Association.


Instruction: When was the ACCF/AHA/AMA-PCPI 2011 report?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ACCF/AHA/AMA-PCPI 2011 report?. ### Response: 2011.


Instruction: What does C on-sortium for Performance Improvement do?

Output: Monitoring the quality oflife in patients with coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does C on-sortium for Performance Improvement do?. ### Response: Monitoring the quality oflife in patients with coronary artery disease.


Instruction: When was Circulation1 24:248–70.437 published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation1 24:248–70.437 published?. ### Response: 2011.


Instruction: What is the economic consequence of noncompliance?

Output: a

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the economic consequence of noncompliance?. ### Response: a.


Instruction: What are the economic consequences of noncompliance in cardiovascular disease and related conditions?

Output: a

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the economic consequences of noncompliance in cardiovascular disease and related conditions?. ### Response: a.


Instruction: Revascularization to Improve Survival Compared With What?

Output: Medical Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Revascularization to Improve Survival Compared With What?. ### Response: Medical Therapy.


Instruction: What is the Heart Team approach recommended for?

Output: C 302–304CABG and PCI IIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Heart Team approach recommended for?. ### Response: C 302–304CABG and PCI IIa.


Instruction: What is a low risk of PCI procedural complications and a high likelihood of good long-term outcome?

Output: Anatomic conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a low risk of PCI procedural complications and a high likelihood of good long-term outcome?. ### Response: Anatomic conditions.


Instruction: What predicts a significantly increased risk of adverse surgical outcomes?

Output: Clinical characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts a significantly increased risk of adverse surgical outcomes?. ### Response: Clinical characteristics.


Instruction: What is STS-predicted risk of operative mortality?

Output: /H113505%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is STS-predicted risk of operative mortality?. ### Response: /H113505%).


Instruction: What is STEMI when distal coronary flow is TIMI flow grade?

Output: /H110213

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is STEMI when distal coronary flow is TIMI flow grade?. ### Response: /H110213.


Instruction: How can flow grade /H110213 and PCI be performed morerapiously and safely than CABGC 321, 338, 339IIb?

Output: distal coronary flow is TIMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can flow grade /H110213 and PCI be performed morerapiously and safely than CABGC 321, 338, 339IIb?. ### Response: distal coronary flow is TIMI.


Instruction: For SIHD when both of the following are present?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For SIHD when both of the following are present?. ### Response: •.


Instruction: A low to intermediate risk of PCI proceduralcomplications and intermediate to high likelihood of good long-term outcome are associated with what?

Output: Anatomic conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A low to intermediate risk of PCI proceduralcomplications and intermediate to high likelihood of good long-term outcome are associated with what?. ### Response: Anatomic conditions.


Instruction: What predicts an increased risk of adverse surgicaloutcomes?

Output: Clinical characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts an increased risk of adverse surgicaloutcomes?. ### Response: Clinical characteristics.


Instruction: What is the STS-predicted risk of operative mortality?

Output: /H113505%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the STS-predicted risk of operative mortality?. ### Response: /H113505%).


Instruction: What type of artery disease is a good candidate for CABGB?

Output: proximal LAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of artery disease is a good candidate for CABGB?. ### Response: proximal LAD.


Instruction: What is another reason to choose CABG over PCI in patients with 3-vesselCAD?

Output: reasonable to choose CABG over PCI in patients with complex 3-vesselCAD (eg, SYNTAX /H1102222) who are good candidates for CABGB 320, 334, 343, 359–360PCI IIb—Of uncertain benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another reason to choose CABG over PCI in patients with 3-vesselCAD?. ### Response: reasonable to choose CABG over PCI in patients with complex 3-vesselCAD (eg, SYNTAX /H1102222) who are good candidates for CABGB 320, 334, 343, 359–360PCI IIb—Of uncertain benefit.


Instruction: What are patients with complex 3-vesselCAD who are good candidates for CABGB 320, 334, 343, 359–360PCI IIb with proximal LAD artery disease with CABG I B 314, 341, 343,3702-vessel disease?

Output: SYNTAX /H1102222

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with complex 3-vesselCAD who are good candidates for CABGB 320, 334, 343, 359–360PCI IIb with proximal LAD artery disease with CABG I B 314, 341, 343,3702-vessel disease?. ### Response: SYNTAX /H1102222.


Instruction: What type of CAD is SYNTAX/H1102222?

Output: complex 3-vessel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of CAD is SYNTAX/H1102222?. ### Response: complex 3-vessel.


Instruction: What type of artery disease is associated with CABG IIa?

Output: proximal LAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of artery disease is associated with CABG IIa?. ### Response: proximal LAD.


Instruction: What types of vascular disease are associated with LIMA for long-term benefit?

Output: vessel disease without proximal LAD artery involvement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What types of vascular disease are associated with LIMA for long-term benefit?. ### Response: vessel disease without proximal LAD artery involvement.


Instruction: What is LIMA for long-term benefit?

Output: B 87, 88, 318, 343PCI IIb—Of uncertain benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LIMA for long-term benefit?. ### Response: B 87, 88, 318, 343PCI IIb—Of uncertain benefit.


Instruction: What is EF/H1102135% without proximal LAD artery involvement?

Output: without significant left main CAD B 318, 352–356, 371, 372PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EF/H1102135% without proximal LAD artery involvement?. ### Response: without significant left main CAD B 318, 352–356, 371, 372PCI.


Instruction: What percentage of sudden cardiac death is associated with ischemia-mediated VT?

Output: 35% to 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of sudden cardiac death is associated with ischemia-mediated VT?. ### Response: 35% to 50%.


Instruction: What is the percentage of revascularization?

Output: 35% to 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of revascularization?. ### Response: 35% to 50%.


Instruction: What are the physiological criteria for revascularization?

Output: anatomic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the physiological criteria for revascularization?. ### Response: anatomic.


Instruction: What is the Harm B 318, 341, 348, 349?

Output: CABG III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Harm B 318, 341, 348, 349?. ### Response: CABG III.


Instruction: What is the name of the Japan Public Health Center-based prospective study?

Output: JPHC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Japan Public Health Center-based prospective study?. ### Response: JPHC.


Instruction: When was the JPHC study conducted?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JPHC study conducted?. ### Response: 2011.


Instruction: What is the name of the prospective study of body mass index and risk of stroke in apparently healthy women?

Output: Stroke Council

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study of body mass index and risk of stroke in apparently healthy women?. ### Response: Stroke Council.


Instruction: When did Circulation. 2005;111:1992–1998.

Output: 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2005;111:1992–1998.. ### Response: 300.


Instruction: What is a waist circumference and waist-hip ratio on?

Output: the risk of total and type-specific stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a waist circumference and waist-hip ratio on?. ### Response: the risk of total and type-specific stroke.


Instruction: What are body mass index, waist circumference, and waist-hip ratio on the risk of total and type-specific stroke?

Output: 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are body mass index, waist circumference, and waist-hip ratio on the risk of total and type-specific stroke?. ### Response: 300.


Instruction: What is the name of the study that investigated race- and sex-specific associations of obesity measures with ischemic stroke.

Output: Atherosclerosis Risk in Communities (ARIC) study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated race- and sex-specific associations of obesity measures with ischemic stroke.. ### Response: Atherosclerosis Risk in Communities (ARIC) study.


Instruction: What are race- and sex-specific associations of obesity measures with ischemic stroke inci-dence in the Atherosclerosis Risk in Communities (ARIC) study?

Output: Body mass index

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are race- and sex-specific associations of obesity measures with ischemic stroke inci-dence in the Atherosclerosis Risk in Communities (ARIC) study?. ### Response: Body mass index.


Instruction: What is the name of the meta-analysis of prospec-tive studies with 2 million participants?

Output: Excess body weight and incidence of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of prospec-tive studies with 2 million participants?. ### Response: Excess body weight and incidence of stroke.


Instruction: How many people participated in a meta-analysis of prospec-tive studies with 2 million participants?

Output: 302

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people participated in a meta-analysis of prospec-tive studies with 2 million participants?. ### Response: 302.


Instruction: What is the name of the study that examined adiposity and risk of stroke in Chinese women?

Output: Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined adiposity and risk of stroke in Chinese women?. ### Response: Stroke.


Instruction: Who did Ye W, Adami HO, Weiderpass E study?

Output: women below age 60

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who did Ye W, Adami HO, Weiderpass E study?. ### Response: women below age 60.


Instruction: What is the name of the prospective study of body size and risk for stroke amongst women below age 60?

Output: Stroke Council

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study of body size and risk for stroke amongst women below age 60?. ### Response: Stroke Council.


Instruction: Who did Rexrode KM, Hennekens CH, Willett WC, Colditz GA, Stampfer MJ, Rich-Edwards JW, Speizer FE, Manson JE?

Output: 305

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who did Rexrode KM, Hennekens CH, Willett WC, Colditz GA, Stampfer MJ, Rich-Edwards JW, Speizer FE, Manson JE?. ### Response: 305.


Instruction: What is the name of the prospective study of body mass index, weight change, and risk of stroke in women?

Output: Japan Public Health Center-based prospective (JPHC) study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study of body mass index, weight change, and risk of stroke in women?. ### Response: Japan Public Health Center-based prospective (JPHC) study.


Instruction: When did JAMA issue 277:1539-1545?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 277:1539-1545?. ### Response: 1997.


Instruction: What was the title of JAMA's 1997 issue?

Output: 277:1539–1545

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of JAMA's 1997 issue?. ### Response: 277:1539–1545.


Instruction: What are the results of a longitudinal study in China?

Output: Body mass index and risk of total and type-specific stroke in Chinese adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of a longitudinal study in China?. ### Response: Body mass index and risk of total and type-specific stroke in Chinese adults.


Instruction: What is the effect of obesity and abdominal fat mass on stroke risk?

Output: Contribution of obesity and abdominal fat mass to risk of stroke and transient ischemic attacks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of obesity and abdominal fat mass on stroke risk?. ### Response: Contribution of obesity and abdominal fat mass to risk of stroke and transient ischemic attacks.


Instruction: What does obesity and abdominal fat mass have to do with risk of stroke and transient ischemic attacks?

Output: Contribution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does obesity and abdominal fat mass have to do with risk of stroke and transient ischemic attacks?. ### Response: Contribution.


Instruction: What is the name of the 2008 issue of Stroke.39:3145–3151?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2008 issue of Stroke.39:3145–3151?. ### Response: 2008.


Instruction: Who is the author of Body mass index and stroke risk in men?

Output: Kurth T, Gaziano JM, Berger K, Kase CS, Rexrode KM, Cook NR, Buring JE, Manson JE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Body mass index and stroke risk in men?. ### Response: Kurth T, Gaziano JM, Berger K, Kase CS, Rexrode KM, Cook NR, Buring JE, Manson JE.


Instruction: When was the last issue of Arch Intern Med published?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of Arch Intern Med published?. ### Response: 2007.


Instruction: In what year did Arch Intern Med issue 162:2557–2562?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Arch Intern Med issue 162:2557–2562?. ### Response: 2002.


Instruction: What is the name of the committee that represents the American Heart Association Obesity Committee?

Output: Council on Nutrition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that represents the American Heart Association Obesity Committee?. ### Response: Council on Nutrition.


Instruction: What is a scientific term for assessing adiposity?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scientific term for assessing adiposity?. ### Response: American Heart Association.


Instruction: What is another term for Physical Activity and Metabolism?

Output: Obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for Physical Activity and Metabolism?. ### Response: Obesity.


Instruction: What is the acronym for the American Heart Association?

Output: Atherosclerosis Risk in Communities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American Heart Association?. ### Response: Atherosclerosis Risk in Communities.


Instruction: When was Circulation. 2011;124:1996-2019?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation. 2011;124:1996-2019?. ### Response: 2011.


Instruction: What is normalized ratio stability?

Output: J Thromb Thrombolysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is normalized ratio stability?. ### Response: J Thromb Thrombolysis.


Instruction: When was J Thromb Thrombolysis. 2011;32(4):426-430.27 NOVEMBER 2018 xVOLUME 2, NUMBER 22 ASH 2018 VTE GUIDELINES: ANTICOAGULATION MANAGEMENT 3287Downloaded from http://ashpublications.org/bloodadvances on what date?

Output: normalized ratio stability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was J Thromb Thrombolysis. 2011;32(4):426-430.27 NOVEMBER 2018 xVOLUME 2, NUMBER 22 ASH 2018 VTE GUIDELINES: ANTICOAGULATION MANAGEMENT 3287Downloaded from http://ashpublications.org/bloodadvances on what date?. ### Response: normalized ratio stability.


Instruction: What is HFrEF and HF with preserved EF?

Output: monitoring strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HFrEF and HF with preserved EF?. ### Response: monitoring strategy.


Instruction: What may guide thera-peutic decision-making in well-selected patients with recurrent congestion?

Output: highly specialized monitoring strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may guide thera-peutic decision-making in well-selected patients with recurrent congestion?. ### Response: highly specialized monitoring strategy.


Instruction: The impact on mortality is un-known but is being evaluated in what?

Output: an ongoing randomizedclinical trial, GUIDE-HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The impact on mortality is un-known but is being evaluated in what?. ### Response: an ongoing randomizedclinical trial, GUIDE-HF.


Instruction: GUIDE-HF (H emodynamic-Guided Manage-ment of HF) is an ongoing randomizedclinical trial.

Output: The impact on mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: GUIDE-HF (H emodynamic-Guided Manage-ment of HF) is an ongoing randomizedclinical trial.. ### Response: The impact on mortality.


Instruction: What type of approach may be needed to deploy emodynamic-Guided Manage-ment ofHF?

Output: team-based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of approach may be needed to deploy emodynamic-Guided Manage-ment ofHF?. ### Response: team-based.


Instruction: Patients on optimal GDMT with high-riskfeatures should be considered for referral to an advancedHF specialist?

Output: electrophysiology special-ists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients on optimal GDMT with high-riskfeatures should be considered for referral to an advancedHF specialist?. ### Response: electrophysiology special-ists.


Instruction: What should be considered for referral to an advancedHF specialist?

Output: Patients on optimal GDMT w ho have either high-riskfeatures ( Section 5.3 and Table 6 ) or a poor response totherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered for referral to an advancedHF specialist?. ### Response: Patients on optimal GDMT w ho have either high-riskfeatures ( Section 5.3 and Table 6 ) or a poor response totherapy.


Instruction: What is essential in selected patients to optimizetherapies and evaluate advanced care options?

Output: Appropriate and timely referral to an HF specialist and/orHF program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is essential in selected patients to optimizetherapies and evaluate advanced care options?. ### Response: Appropriate and timely referral to an HF specialist and/orHF program.


Instruction: What are some of the options for HF care?

Output: implantable cardioverter-de ﬁbrillator or cardiac resynch-ronization therapy devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the options for HF care?. ### Response: implantable cardioverter-de ﬁbrillator or cardiac resynch-ronization therapy devices.


Instruction: What is a clinical trigger for referral?

Output: persistent or worsening symptoms,adverse clinical events, or oth er features suggesting thatthe patient is at high risk for disease progression or death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a clinical trigger for referral?. ### Response: persistent or worsening symptoms,adverse clinical events, or oth er features suggesting thatthe patient is at high risk for disease progression or death.


Instruction: Where should referrals be made?

Output: consultation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where should referrals be made?. ### Response: consultation.


Instruction: What are clinical triggers for referral?

Output: persistent or worsening symptoms,adverse clinical events, or oth er features suggesting thatthe patient is at high risk for disease progression or death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are clinical triggers for referral?. ### Response: persistent or worsening symptoms,adverse clinical events, or oth er features suggesting thatthe patient is at high risk for disease progression or death.


Instruction: What is the range of treatments available for?

Output: patients with HFrEF, include m ultiple medications, car-diac devices, surgery, and lifestyle adaptations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the range of treatments available for?. ### Response: patients with HFrEF, include m ultiple medications, car-diac devices, surgery, and lifestyle adaptations.


Instruction: What type of medications are available for patients with HFrEF?

Output: m ultiple

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of medications are available for patients with HFrEF?. ### Response: m ultiple.


Instruction: What are some of the treatments available?

Output: heart transplantation ormechanical circulatory support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the treatments available?. ### Response: heart transplantation ormechanical circulatory support.


Instruction: Who delivers electrophysiology special-ists to implant, monitor, and adjust devices?

Output: consultative care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who delivers electrophysiology special-ists to implant, monitor, and adjust devices?. ### Response: consultative care.