Instruction: What does the ASH guideline panel recommend against for patients receiving anticoagulation therapy for treatment of VTE?

Output: using adaily lottery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ASH guideline panel recommend against for patients receiving anticoagulation therapy for treatment of VTE?. ### Response: using adaily lottery.


Instruction: What does ASH recommend against using?

Output: adaily lottery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ASH recommend against using?. ### Response: adaily lottery.


Instruction: What is the recommendation based on?

Output: very low cer-tainty in the evidence about effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommendation based on?. ### Response: very low cer-tainty in the evidence about effects.


Instruction: What type of alert system was used in the study evaluated by the panel?

Output: sophisticated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of alert system was used in the study evaluated by the panel?. ### Response: sophisticated.


Instruction: One RCT reported the effect of what?

Output: adaily lottery-based incentive intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: One RCT reported the effect of what?. ### Response: adaily lottery-based incentive intervention.


Instruction: What was the main outcome of the EtD framework?

Output: anticoagulation control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the main outcome of the EtD framework?. ### Response: anticoagulation control.


Instruction: What is shown online at https://dbep.gradepro.org/profile/06290825-AF53-134F-9191-7E26113C0FDA?

Output: The EtD framework

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shown online at https://dbep.gradepro.org/profile/06290825-AF53-134F-9191-7E26113C0FDA?. ### Response: The EtD framework.


Instruction: For benefits, see what in the EtDframework referenced at the end of the previous section?

Output: evidence profile

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For benefits, see what in the EtDframework referenced at the end of the previous section?. ### Response: evidence profile.


Instruction: The percentage time outside of the INR range was lower in thegroup with what?

Output: the daily lottery plus electronic reminder

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The percentage time outside of the INR range was lower in thegroup with what?. ### Response: the daily lottery plus electronic reminder.


Instruction: What was the CI of electronic reminder than in controls?

Output: 0.27-3.89

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the CI of electronic reminder than in controls?. ### Response: 0.27-3.89.


Instruction: What was adjusted OR for likelihood of being out of INR range?

Output: 0.77

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was adjusted OR for likelihood of being out of INR range?. ### Response: 0.77.


Instruction: What are the major risk factors for ICH?

Output: Treatment of ICHOlder age, female sex, low body weight (<70 kg [female] and <80 kg [male]), prior stroke, and hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the major risk factors for ICH?. ### Response: Treatment of ICHOlder age, female sex, low body weight (<70 kg [female] and <80 kg [male]), prior stroke, and hypertension.


Instruction: What is the graded increase beginning at >160 to 170 mm Hg systolic?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the graded increase beginning at >160 to 170 mm Hg systolic?. ### Response: hypertension.


Instruction: What should all antiplatelet and anticoagulant therapy be stopped once ICH is rec-ognized?

Output: Brain imaging with emergency neurological and neurosurgical consultation is required

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all antiplatelet and anticoagulant therapy be stopped once ICH is rec-ognized?. ### Response: Brain imaging with emergency neurological and neurosurgical consultation is required.


Instruction: Brain imaging with emergency neurological and neurosurgical consultation is required what?

Output: Once ICH is rec-ognized, all antiplatelet and anticoagulant therapy should be stopped

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Brain imaging with emergency neurological and neurosurgical consultation is required what?. ### Response: Once ICH is rec-ognized, all antiplatelet and anticoagulant therapy should be stopped.


Instruction: What can be given consideration to the use of protamine?

Output: fresh frozen plasma, prothrom-bin complex concentrates, activated factor VII,555 and platelets as indicated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be given consideration to the use of protamine?. ### Response: fresh frozen plasma, prothrom-bin complex concentrates, activated factor VII,555 and platelets as indicated.


Instruction: What is the most common type of bleeding after STEMI?

Output: Vascular access site bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common type of bleeding after STEMI?. ### Response: Vascular access site bleeding.


Instruction: What should be individualized and guided by neurosurgical consultation?

Output: Resumption and timing of anticoagulant and/or antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be individualized and guided by neurosurgical consultation?. ### Response: Resumption and timing of anticoagulant and/or antiplatelet therapy.


Instruction: What has been identified as a risk factor for femoral access site bleeding after PCI?

Output: lar-weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been identified as a risk factor for femoral access site bleeding after PCI?. ### Response: lar-weight heparin.


Instruction: What are the risk factors for bleeding within 48 hours of PCI after a PCI procedure?

Output: female sex, advanced age, renal insufficiency, ane-mia, IABP, use of GP IIb/IIIa antagonists, and low-molecu-lar-weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risk factors for bleeding within 48 hours of PCI after a PCI procedure?. ### Response: female sex, advanced age, renal insufficiency, ane-mia, IABP, use of GP IIb/IIIa antagonists, and low-molecu-lar-weight heparin.


Instruction: How long does it take for heparin to activate clotting?

Output: higher activated clotting times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for heparin to activate clotting?. ### Response: higher activated clotting times.


Instruction: What increases the risk of access site bleeding and should be avoided?

Output: Larger sheath size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the risk of access site bleeding and should be avoided?. ### Response: Larger sheath size.


Instruction: What may decrease bleeding complications?

Output: Radial artery access

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may decrease bleeding complications?. ### Response: Radial artery access.


Instruction: How is procedural success with radial artery access dependent on operator experience?

Output: Radial artery access may decrease bleeding complications and should be con-sidered whenever feasible,558

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is procedural success with radial artery access dependent on operator experience?. ### Response: Radial artery access may decrease bleeding complications and should be con-sidered whenever feasible,558.


Instruction: What is dependent on operator experience?

Output: procedural success

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is dependent on operator experience?. ### Response: procedural success.


Instruction: In the RIV AL trial, radial artery access appeared to reduce the rate of what?

Output: bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the RIV AL trial, radial artery access appeared to reduce the rate of what?. ### Response: bleeding complications.


Instruction: What is the primary composite outcome of triple therapy?

Output: death, MI, stroke, non–CABG-related

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary composite outcome of triple therapy?. ### Response: death, MI, stroke, non–CABG-related.


Instruction: What is a 3- to 4-fold increased risk of fatal and nonfatal bleeding?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 3- to 4-fold increased risk of fatal and nonfatal bleeding?. ### Response: triple therapy.


Instruction: How much increased is the risk of fatal bleeding?

Output: 3- to 4-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increased is the risk of fatal bleeding?. ### Response: 3- to 4-fold.


Instruction: What does CI stand for?

Output: confidence interval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CI stand for?. ### Response: confidence interval.


Instruction: How does HR stand for myocardial infarction?

Output: hazard ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does HR stand for myocardial infarction?. ### Response: hazard ratio.


Instruction: Where did Srensen get permission to use this information?

Output: Sørensen et al.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did Srensen get permission to use this information?. ### Response: Sørensen et al..


Instruction: What is the gender of the patient with diabetes mellitus?

Output: Female

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the gender of the patient with diabetes mellitus?. ### Response: Female.


Instruction: What type of GI bleeding is present in patients with STEMI or NSTEMI (vs UA)?

Output: History

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of GI bleeding is present in patients with STEMI or NSTEMI (vs UA)?. ### Response: History.


Instruction: How is CrCl measured?

Output: creatinine clearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is CrCl measured?. ### Response: creatinine clearance.


Instruction: What is CrCl?

Output: creatinine clearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CrCl?. ### Response: creatinine clearance.


Instruction: What is HF?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HF?. ### Response: heart failure.


Instruction: Where is UA from?

Output: unstable  angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is UA from?. ### Response: unstable  angina.


Instruction: When was UA downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was UA downloaded?. ### Response: April 28, 2023.


Instruction: What is used for Management of ACC/AHA Stage 1?

Output: HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used for Management of ACC/AHA Stage 1?. ### Response: HBPM.


Instruction: What does HBPM combine with PM-5 and QM-5?

Output: Composite Measure Combining PM-5 and QM-5)QM-6: Use of HBPM for Management of ACC/AHA Stage 1 HBP or ACC/AHA Stage 2 HBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HBPM combine with PM-5 and QM-5?. ### Response: Composite Measure Combining PM-5 and QM-5)QM-6: Use of HBPM for Management of ACC/AHA Stage 1 HBP or ACC/AHA Stage 2 HBP.


Instruction: What is used for Management of ACC/AHA Stage 1 HBP?

Output: HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used for Management of ACC/AHA Stage 1 HBP?. ### Response: HBPM.


Instruction: What is combined with PM-5 and Process QM-5)?

Output: Composite Measure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is combined with PM-5 and Process QM-5)?. ### Response: Composite Measure.


Instruction: What is recommended for patients with ACC/AHA stage 1 HBP?

Output: HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with ACC/AHA stage 1 HBP?. ### Response: HBPM.


Instruction: Where are HBPM data documented?

Output: in the patient record

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are HBPM data documented?. ### Response: in the patient record.


Instruction: What is documented in the patient record?

Output: HBPM data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is documented in the patient record?. ### Response: HBPM data.


Instruction: Who had at least 1 outpatient encounter with a diagnosis of HBP during the first 6 mo of the measurement year or any time before the measurement period?

Output: All patients 18–85 y of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who had at least 1 outpatient encounter with a diagnosis of HBP during the first 6 mo of the measurement year or any time before the measurement period?. ### Response: All patients 18–85 y of age.


Instruction: End-stage renal disease, kidney transplantation, pregnancy, BP readings?

Output: inpatient stay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: End-stage renal disease, kidney transplantation, pregnancy, BP readings?. ### Response: inpatient stay.


Instruction: What is the term for end stage renal disease, kidney transplantation, pregnancy, BP readings taken during an inpatient stay?

Output: Denominator Exclusions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for end stage renal disease, kidney transplantation, pregnancy, BP readings taken during an inpatient stay?. ### Response: Denominator Exclusions.


Instruction: What is another term for expanded administrative data?

Output: multiple source

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for expanded administrative data?. ### Response: multiple source.


Instruction: What is HBPM?

Output: self-monitoring of BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HBPM?. ### Response: self-monitoring of BP.


Instruction: What is self-monitoring?

Output: regular measurement of BP by an individual at home or elsewhere outside the clinic setting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is self-monitoring?. ### Response: regular measurement of BP by an individual at home or elsewhere outside the clinic setting.


Instruction: What does BP refer to?

Output: Care Setting Outpatient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does BP refer to?. ### Response: Care Setting Outpatient.


Instruction: What has been found to be a better predictor of cardiovascular risk than clinic-based measurement?

Output: Home-based measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been found to be a better predictor of cardiovascular risk than clinic-based measurement?. ### Response: Home-based measurement.


Instruction: Evidence suggests that home-based BP measurement in combination interventions with what?

Output: telemedicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence suggests that home-based BP measurement in combination interventions with what?. ### Response: telemedicine.


Instruction: Home-based BP measurement in combination with telemedicine with nurse- or pharmacist-led care may be effective for improving what?

Output: hypertension management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Home-based BP measurement in combination with telemedicine with nurse- or pharmacist-led care may be effective for improving what?. ### Response: hypertension management.


Instruction: What are the recommended procedures for the collection of HBPM data?

Output: Monitors with provision for storage of readings in memory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommended procedures for the collection of HBPM data?. ### Response: Monitors with provision for storage of readings in memory.


Instruction: What is not generally useful for HBPM?

Output: Use of auscultatory devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not generally useful for HBPM?. ### Response: Use of auscultatory devices.


Instruction: What are auscultatory devices?

Output: mercury, aneroid, or other

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are auscultatory devices?. ### Response: mercury, aneroid, or other.


Instruction: What is not generally useful for HBPM because patients rarely master the technique required for measuring BP with auscultatory devices?

Output: Use of auscultatory devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not generally useful for HBPM because patients rarely master the technique required for measuring BP with auscultatory devices?. ### Response: Use of auscultatory devices.


Instruction: What is preferred?

Output: Monitors with provision for storage of readings in memory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preferred?. ### Response: Monitors with provision for storage of readings in memory.


Instruction: What are beta-blockers used for in heart failure and concomitant atrial fibrillation?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are beta-blockers used for in heart failure and concomitant atrial fibrillation?. ### Response: Chronic Heart Failure.


Instruction: What is the name of the drug used to treat heart failure?

Output: Beta -blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat heart failure?. ### Response: Beta -blockers.


Instruction: Who is the author of this study?

Output: 978 -1-4731 -3093 -7 119

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of this study?. ### Response: 978 -1-4731 -3093 -7 119.


Instruction: What do people with dilutional hyponatr aemia need to restrict?

Output: fluids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do people with dilutional hyponatr aemia need to restrict?. ### Response: fluids.


Instruction: What does reducing intake for people with high levels of salt and/or fluid consumption do?

Output: restricting fluids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does reducing intake for people with high levels of salt and/or fluid consumption do?. ### Response: restricting fluids.


Instruction: What do people with heart failure need to avoid?

Output: salt substitutes that contain potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do people with heart failure need to avoid?. ### Response: salt substitutes that contain potassium.


Instruction: What did the committee consider that provided further support for its recommendation?

Output: non -random ised evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee consider that provided further support for its recommendation?. ### Response: non -random ised evidence.


Instruction: ised evidence provided further support for its recommendation to not routinely offer sodium restriction until what is available?

Output: randomised evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ised evidence provided further support for its recommendation to not routinely offer sodium restriction until what is available?. ### Response: randomised evidence.


Instruction: Current practice regarding salt and fluid restriction is highly variable with some healthcare professio nals advising patients to restrict intake and others not?

Output: The lay members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Current practice regarding salt and fluid restriction is highly variable with some healthcare professio nals advising patients to restrict intake and others not?. ### Response: The lay members.


Instruction: What is the subject of much discussion in patient groups?

Output: salt and fluid restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the subject of much discussion in patient groups?. ### Response: salt and fluid restriction.


Instruction: What is one of a limited number of opportunities for self management in HF?

Output: salt and fluid restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of a limited number of opportunities for self management in HF?. ### Response: salt and fluid restriction.


Instruction: What may patients feel allows them to exercise some personal control over the course of what is an unpredictable and serious long term condition?

Output: salt and fluid restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients feel allows them to exercise some personal control over the course of what is an unpredictable and serious long term condition?. ### Response: salt and fluid restriction.


Instruction: What has led to confusion and uncertainty among patients about wh ether salt and fluid restriction is necessary or not?

Output: variation in practice and advice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has led to confusion and uncertainty among patients about wh ether salt and fluid restriction is necessary or not?. ### Response: variation in practice and advice.


Instruction: What is the purpose of not routinely advising salt and fluid restriction?

Output: to reduce variation in practice across the country

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of not routinely advising salt and fluid restriction?. ### Response: to reduce variation in practice across the country.


Instruction: What should discussions between patients and healers start from?

Output: a consistent position

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should discussions between patients and healers start from?. ### Response: a consistent position.


Instruction: What should healthcare professionals start from?

Output: a consistent position

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should healthcare professionals start from?. ### Response: a consistent position.


Instruction: What should patients be able to discuss with their healthcare professionals?

Output: salt and fluid restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients be able to discuss with their healthcare professionals?. ### Response: salt and fluid restriction.


Instruction: What may patients have been asked to restrict during acute episodes?

Output: fluid intake

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients have been asked to restrict during acute episodes?. ### Response: fluid intake.


Instruction: What should the decision on whether to continue to restrict salt and/or fluid take into account?

Output: patient preferences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the decision on whether to continue to restrict salt and/or fluid take into account?. ### Response: patient preferences.


Instruction: What is ACEIs?

Output: Angiotensin-Converting EnzymeInhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACEIs?. ### Response: Angiotensin-Converting EnzymeInhibitors.


Instruction: What is AIIRA?

Output: Angiotensin II Receptor Antago-nists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AIIRA?. ### Response: Angiotensin II Receptor Antago-nists.


Instruction: When was the AIIRA report released?

Output: March 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the AIIRA report released?. ### Response: March 2006.


Instruction: What is ACCOMPLISH?

Output: a prespeciﬁed secondaryanalysis of a randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACCOMPLISH?. ### Response: a prespeciﬁed secondaryanalysis of a randomised controlled trial.


Instruction: What is the name of the prespecified secondaryanalysis of a randomised controlled trial?

Output: ACCOMPLISH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prespecified secondaryanalysis of a randomised controlled trial?. ### Response: ACCOMPLISH.


Instruction: How is aldosterone used in clinicalnephrology?

Output: old hormone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is aldosterone used in clinicalnephrology?. ### Response: old hormone.


Instruction: What is the name of the drug used to treat resistant hypertension?

Output: Goodfriend TL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat resistant hypertension?. ### Response: Goodfriend TL.


Instruction: What does eplerenone reduce in patients with type 2 diabetes?

Output: albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does eplerenone reduce in patients with type 2 diabetes?. ### Response: albuminuria.


Instruction: What does aldosteroneblockade reduce in type 2 diabetic patients?

Output: albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does aldosteroneblockade reduce in type 2 diabetic patients?. ### Response: albuminuria.


Instruction: What did Bomback AS, Kshirsagar AV, Amamoo MA et al. Do aldosterone blockers or angiotensin receptorblockers cause a change in proteinuria?

Output: adding aldosterone blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Bomback AS, Kshirsagar AV, Amamoo MA et al. Do aldosterone blockers or angiotensin receptorblockers cause a change in proteinuria?. ### Response: adding aldosterone blockers.


Instruction: What was the name of the systematic review in 2008?

Output: Am J Kidney Dis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the systematic review in 2008?. ### Response: Am J Kidney Dis.


Instruction: When was the Am J Kidney Dis 2008: 51: 199-211.108?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Kidney Dis 2008: 51: 199-211.108?. ### Response: 2008.


Instruction: What is an antagonism to angiotensin receptorblockade in diabetic nephropathy?

Output: mineralocorticoid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an antagonism to angiotensin receptorblockade in diabetic nephropathy?. ### Response: mineralocorticoid.


Instruction: What is the effect of spironolactoneon proteinuria on kidney function in patients with chronic kidneydisease?

Output: Long-term effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of spironolactoneon proteinuria on kidney function in patients with chronic kidneydisease?. ### Response: Long-term effects.


Instruction: In what year was Kidney Int 70: 2116-21212?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was Kidney Int 70: 2116-21212?. ### Response: 2006.


Instruction: What does cyclosporine do to aliskiren in healthy subjects?

Output: pharmacokinetics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does cyclosporine do to aliskiren in healthy subjects?. ### Response: pharmacokinetics.


Instruction: When was Kidney Int 2006 published?

Output: 70: 2116– 2123.110

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Kidney Int 2006 published?. ### Response: 70: 2116– 2123.110.


Instruction: What is the name of the drug that blocks aldosterone in chronic kidney disease?

Output: cyclosporine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that blocks aldosterone in chronic kidney disease?. ### Response: cyclosporine.


Instruction: What is the pharmacokinetics of aliskiren in healthy subjects?

Output: Effect of cyclosporine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pharmacokinetics of aliskiren in healthy subjects?. ### Response: Effect of cyclosporine.


Instruction: What was the J Clin Pharmacol 2011:51: 1549–1560.112?

Output: aliskiren

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Clin Pharmacol 2011:51: 1549–1560.112?. ### Response: aliskiren.


Instruction: Aliskiren combined with losartan intype 2 diabetes and nephropathy?

Output: angiotensin receptorblockade or mineralocorticoid antagonism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aliskiren combined with losartan intype 2 diabetes and nephropathy?. ### Response: angiotensin receptorblockade or mineralocorticoid antagonism.


Instruction: What does ALTITUDE stand for?

Output: Aliskiren Trial in Type 2Diabetes Using Cardio-Renal Endpoints

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ALTITUDE stand for?. ### Response: Aliskiren Trial in Type 2Diabetes Using Cardio-Renal Endpoints.


Instruction: What is the name of the study that used cardio-renal endpoints?

Output: Aliskiren Trial in Type 2Diabetes Using Cardio-Renal Endpoints (ALTITUDE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that used cardio-renal endpoints?. ### Response: Aliskiren Trial in Type 2Diabetes Using Cardio-Renal Endpoints (ALTITUDE.


Instruction: When was Nephrol Dial Transplant 2009 published?

Output: 24

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Nephrol Dial Transplant 2009 published?. ### Response: 24.


Instruction: Who is responsible for the FDA drug safety communication?

Output: US Food and Drug Administration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is responsible for the FDA drug safety communication?. ### Response: US Food and Drug Administration.


Instruction: What does Tekturna stand for?

Output: aliskiren

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Tekturna stand for?. ### Response: aliskiren.


Instruction: What is the name of the drug that is used to treat hypertension?

Output: Spironolactone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat hypertension?. ### Response: Spironolactone.


Instruction: Who is the author of the study on diuretics?

Output: Weinberger

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study on diuretics?. ### Response: Weinberger.


Instruction: What is the SWISSI II randomized controlled trial?

Output: Effects of percutaneous coronary interventions in silent ischemia after myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the SWISSI II randomized controlled trial?. ### Response: Effects of percutaneous coronary interventions in silent ischemia after myocardial infarction.


Instruction: What is a common cause of silent ischemia after myocardial infarction?

Output: thrombolysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of silent ischemia after myocardial infarction?. ### Response: thrombolysis.


Instruction: What is DANAMI?

Output: DANish trial in Acute Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DANAMI?. ### Response: DANish trial in Acute Myocardial Infarction.


Instruction: When was the DANish trial in Acute Myocardial Infarction conducted?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the DANish trial in Acute Myocardial Infarction conducted?. ### Response: 1997.


Instruction: What is the role of adjunctive thrombectomy and embolic protection devices?

Output: a com-prehensive meta-analysis of randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of adjunctive thrombectomy and embolic protection devices?. ### Response: a com-prehensive meta-analysis of randomized trials.


Instruction: What are embolic protection devices used for in acute myocardial infarction?

Output: adjunctive thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are embolic protection devices used for in acute myocardial infarction?. ### Response: adjunctive thrombectomy.


Instruction: What is the name of the thrombus aspiration during primary percutaneous coronary intervention?

Output: EXPIRA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the thrombus aspiration during primary percutaneous coronary intervention?. ### Response: EXPIRA.


Instruction: What is the name of the prospective, randomized trial infarct size?

Output: EXPIRA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective, randomized trial infarct size?. ### Response: EXPIRA.


Instruction: What is EXPIRA?

Output: Thrombectomy With Export Catheter in Infarct-Related Artery During Primary Percutaneous Coronary Intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EXPIRA?. ### Response: Thrombectomy With Export Catheter in Infarct-Related Artery During Primary Percutaneous Coronary Intervention.


Instruction: How long did it take to achieve results from a rheolytic thrombectomy?

Output: 30-day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to achieve results from a rheolytic thrombectomy?. ### Response: 30-day.


Instruction: How long did it take to reduce size in acute myocardial infarction?

Output: 30-day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to reduce size in acute myocardial infarction?. ### Response: 30-day.


Instruction: What is the JET -STENT trial?

Output: Comparison of AngioJet rheolytic thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JET -STENT trial?. ### Response: Comparison of AngioJet rheolytic thrombectomy.


Instruction: What is the name of the trial in patients with acute myocardial infarction?

Output: JET -STENT trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial in patients with acute myocardial infarction?. ### Response: JET -STENT trial.


Instruction: When was the JET -STENT trial conducted?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JET -STENT trial conducted?. ### Response: 2010.


Instruction: What was the outcome of primary stenting versus balloon angioplasty?

Output: Clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of primary stenting versus balloon angioplasty?. ### Response: Clinical outcomes.


Instruction: What is the difference between stent implantation and balloon angioplasty for acute myocardial infarction?

Output: Primary stent implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between stent implantation and balloon angioplasty for acute myocardial infarction?. ### Response: Primary stent implantation.


Instruction: When did Spertus JA, Kettelkamp R, Vance C, et al. publish?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Spertus JA, Kettelkamp R, Vance C, et al. publish?. ### Response: 2001.


Instruction: What is the PREMIER registry used for?

Output: meta-analysis of randomized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PREMIER registry used for?. ### Response: meta-analysis of randomized controlled trials.


Instruction: What are the results from?

Output: 30-day results from a multicenter randomized study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results from?. ### Response: 30-day results from a multicenter randomized study.


Instruction: When was thienopyridine therapy discontinued?

Output: after drug-eluting stent placement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was thienopyridine therapy discontinued?. ### Response: after drug-eluting stent placement.


Instruction: What is the name of the science advisory for premature dis-continuation of dual antiplatelet therapy in patients with coronary artery stents?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the science advisory for premature dis-continuation of dual antiplatelet therapy in patients with coronary artery stents?. ### Response: American Heart Association.


Instruction: Who represents the American College of Physicians?

Output: American Dental As-sociation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who represents the American College of Physicians?. ### Response: American Dental As-sociation.


Instruction: Circulation. 2007;115:813–8.

Output: PREMIER registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2007;115:813–8.. ### Response: PREMIER registry.


Instruction: What can stress testing help with in most cases?

Output: planning further tests and treatments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can stress testing help with in most cases?. ### Response: planning further tests and treatments.


Instruction: What can be created on the basis of data from current regis-tries and trials to identify patients with anatomicdistributions of CAD?

Output: valid,quantitative models

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be created on the basis of data from current regis-tries and trials to identify patients with anatomicdistributions of CAD?. ### Response: valid,quantitative models.


Instruction: What has been shown to improve survival in CAD?

Output: revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to improve survival in CAD?. ### Response: revascularization.


Instruction: What should be a research priority?

Output: Creation of valid,quantitative models on the basis of data from current regis-tries and trials to accurately identify patients with anatomicdistributions of CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be a research priority?. ### Response: Creation of valid,quantitative models on the basis of data from current regis-tries and trials to accurately identify patients with anatomicdistributions of CAD.


Instruction: In addition to C-reactive protein, what is another novel biomarker?

Output: brain natriureticpeptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to C-reactive protein, what is another novel biomarker?. ### Response: brain natriureticpeptide.


Instruction: What are some of the inflamma-tory biomarkers of lipid-related atherogenic processes?

Output: myeloperoxidase,256biochemicalmarkers of lipid-related atherogenic processes [lipoprotein(a),apolipoprotein B, small dense LDL, and lipoprotein-associated phospholipase A2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the inflamma-tory biomarkers of lipid-related atherogenic processes?. ### Response: myeloperoxidase,256biochemicalmarkers of lipid-related atherogenic processes [lipoprotein(a),apolipoprotein B, small dense LDL, and lipoprotein-associated phospholipase A2.


Instruction: What is the name of the small dense LDL and lipoprotein-associated phospholipase A2?

Output: apolipoprotein B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the small dense LDL and lipoprotein-associated phospholipase A2?. ### Response: apolipoprotein B.


Instruction: What are indices of risk in patients with SIHD?

Output: sensitivity assays259

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are indices of risk in patients with SIHD?. ### Response: sensitivity assays259.


Instruction: What type of imaging to assess Cardiac Structure and Function: Recommendations?

Output: Resting Imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of imaging to assess Cardiac Structure and Function: Recommendations?. ### Response: Resting Imaging.


Instruction: Doppler echocardiogra-phy is used in patients with what type of IHD?

Output: known or suspected

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Doppler echocardiogra-phy is used in patients with what type of IHD?. ### Response: known or suspected.


Instruction: What type of waves are used in the assessment of resting LV systolic and diastlic ven-tricular function?

Output: pathological Q waves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of waves are used in the assessment of resting LV systolic and diastlic ven-tricular function?. ### Response: pathological Q waves.


Instruction: What is a nomogram to predict risk ofdeath based on clinical data and results of exercise testing?

Output: Figure 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a nomogram to predict risk ofdeath based on clinical data and results of exercise testing?. ### Response: Figure 8.


Instruction: What is the vertical line from each riskmarker to the top line labeled?

Output: POINTS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the vertical line from each riskmarker to the top line labeled?. ### Response: POINTS.


Instruction: What is marked on the line labeled "TOTAL POINTS"?

Output: The sum of all these points

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is marked on the line labeled "TOTAL POINTS"?. ### Response: The sum of all these points.


Instruction: For binary variables, 1means yes and 0 means what?

Output: no

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For binary variables, 1means yes and 0 means what?. ### Response: no.


Instruction: What indi-cates metabolic equivalent?

Output: MET

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indi-cates metabolic equivalent?. ### Response: MET.


Instruction: What is Stable Ischemic Heart Disease: Full Text e381Download from http://ahajournals.org by on May 1, 2023?

Output: Fihn et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Stable Ischemic Heart Disease: Full Text e381Download from http://ahajournals.org by on May 1, 2023?. ### Response: Fihn et al.


Instruction: What is the difference between 4-factor PCC and FFP?

Output: benefits and harms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between 4-factor PCC and FFP?. ### Response: benefits and harms.


Instruction: What was the guideline panel's assessment of benefits and harms?

Output: balanced based on very lowTable 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the guideline panel's assessment of benefits and harms?. ### Response: balanced based on very lowTable 4.


Instruction: How many mo VTE within past 3 mo previously?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mo VTE within past 3 mo previously?. ### Response: 12.


Instruction: What is another risk factor?

Output: Deficiency of protein C,protein S, or antithrombin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another risk factor?. ### Response: Deficiency of protein C,protein S, or antithrombin.


Instruction: When was this article published?

Output: 27 NOVEMBER 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: 27 NOVEMBER 2018.


Instruction: What does SIHD stand for?

Output: stable is-chemic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SIHD stand for?. ### Response: stable is-chemic heart disease.


Instruction: What is the name of the abbreviation used in this document?

Output: low-risk unstable angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the abbreviation used in this document?. ### Response: low-risk unstable angina.


Instruction: What does CI stand for?

Output: i-dence intervals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CI stand for?. ### Response: i-dence intervals.


Instruction: What is an example of an CI?

Output: confi-dence intervals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an CI?. ### Response: confi-dence intervals.


Instruction: What is an example of a relative treatmenteffects?

Output: odds ratio (OR), relative risk (RR), hazardratio, or incidence rate ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a relative treatmenteffects?. ### Response: odds ratio (OR), relative risk (RR), hazardratio, or incidence rate ratio.


Instruction: What was the writing committee composed of?

Output: physicians, cardiova s-cular interventionalists, surgeons, general internists, imagers,nurses, and pharmacists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the writing committee composed of?. ### Response: physicians, cardiova s-cular interventionalists, surgeons, general internists, imagers,nurses, and pharmacists.


Instruction: Who were members of the Writing Committee?

Output: physicians, cardiova s-cular interventionalists, surgeons, general internists, imagers,nurses, and pharmacists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were members of the Writing Committee?. ### Response: physicians, cardiova s-cular interventionalists, surgeons, general internists, imagers,nurses, and pharmacists.


Instruction: What committee included re pre-sentatives from the ACP, AATS, PCNA, SCAI, and STS?

Output: Organization of the Writing Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What committee included re pre-sentatives from the ACP, AATS, PCNA, SCAI, and STS?. ### Response: Organization of the Writing Committee.


Instruction: How many external reviewers were nomi-nated by both the ACCF and the AHA?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many external reviewers were nomi-nated by both the ACCF and the AHA?. ### Response: 2.


Instruction: How many reviewers contributed to the publication of the guideline?

Output: 19

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many reviewers contributed to the publication of the guideline?. ### Response: 19.


Instruction: What was collected and distributed to the writingcommittee?

Output: Reviewers’ RWIinformation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was collected and distributed to the writingcommittee?. ### Response: Reviewers’ RWIinformation.


Instruction: Why did extensive peer review comments result in substantial revision?

Output: the guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did extensive peer review comments result in substantial revision?. ### Response: the guideline.


Instruction: What resulted in substantial revision?

Output: peer review comments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What resulted in substantial revision?. ### Response: peer review comments.


Instruction: What was the guideline subjected to a second peerreview by?

Output: all official and organizational reviewers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the guideline subjected to a second peerreview by?. ### Response: all official and organizational reviewers.


Instruction: What are the gov-erning bodies of the ACCF, AHA, ACP, AATS, PCNA,SCAI, and STS.1.4 intended to apply to?

Output: adult patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the gov-erning bodies of the ACCF, AHA, ACP, AATS, PCNA,SCAI, and STS.1.4 intended to apply to?. ### Response: adult patients.


Instruction: What is low-risk unstable angina?

Output: new-onset chestpain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low-risk unstable angina?. ### Response: new-onset chestpain.


Instruction: What type of pain syndrome are patients with ischemic equivalents included in?

Output: dyspnea or arm pain withexertion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of pain syndrome are patients with ischemic equivalents included in?. ### Response: dyspnea or arm pain withexertion.


Instruction: What can many patients with IHD become asymptomatic with?

Output: appropriate therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can many patients with IHD become asymptomatic with?. ### Response: appropriate therapy.


Instruction: What does PCI stand for?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PCI stand for?. ### Response: percutaneous coronary intervention.


Instruction: What is another name for CABG?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for CABG?. ### Response: percutaneous coronary intervention.


Instruction: How does this guideline address symptoms that suggest IHD?

Output: initial diagnostic ap-proach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does this guideline address symptoms that suggest IHD?. ### Response: initial diagnostic ap-proach.


Instruction: What type of angina is a sign of obstructive CAD or an increase in CAD?

Output: chronic stable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of angina is a sign of obstructive CAD or an increase in CAD?. ### Response: chronic stable.


Instruction: What kind of CAD is an example of chronic stable angina?

Output: obstructive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What kind of CAD is an example of chronic stable angina?. ### Response: obstructive.


Instruction: What is the name of the condition that causes preeclampsia in pregnant women?

Output: severe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the condition that causes preeclampsia in pregnant women?. ### Response: severe.


Instruction: In what year did the Am J Med issue 120 of 819?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the Am J Med issue 120 of 819?. ### Response: 2007.


Instruction: What was the diagnosis of acute myocardial infarction?

Output: within 3 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the diagnosis of acute myocardial infarction?. ### Response: within 3 hours.


Instruction: What is a point-of-care test for acute myocardial infarction within 3 hours after presentation in early presenters to the emergency department with chest pain?

Output: troponin I assay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a point-of-care test for acute myocardial infarction within 3 hours after presentation in early presenters to the emergency department with chest pain?. ### Response: troponin I assay.


Instruction: What is the long-term prognostic value of serial troponin T bedside tests?

Output: acute coronary syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term prognostic value of serial troponin T bedside tests?. ### Response: acute coronary syndromes.


Instruction: What type of bedside tests are used in patients with acute coronary syndromes?

Output: serial troponin T

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of bedside tests are used in patients with acute coronary syndromes?. ### Response: serial troponin T.


Instruction: What is the name of the drug used in early and late outcome prediction of death in the emergency room setting?

Output: cardiac troponin I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used in early and late outcome prediction of death in the emergency room setting?. ### Response: cardiac troponin I.


Instruction: What is the name of the drug that can be used to stratify patients with acute coronary syndromes?

Output: tirofiban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that can be used to stratify patients with acute coronary syndromes?. ### Response: tirofiban.


Instruction: What are the names of the investigators of the PRISM Study?

Output: Heeschen C, Hamm CW, Goldmann B, et al. Troponin concentrations for stratification of patients with acute coronary syndromes in relation to thera-peutic efficacy of tirofiban. PRISM Study Investigators. Platelet Receptor Inhibition in Ischemic Syndrome Management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the investigators of the PRISM Study?. ### Response: Heeschen C, Hamm CW, Goldmann B, et al. Troponin concentrations for stratification of patients with acute coronary syndromes in relation to thera-peutic efficacy of tirofiban. PRISM Study Investigators. Platelet Receptor Inhibition in Ischemic Syndrome Management.


Instruction: In what year did the Lancet publish a study on Platelet Receptor Inhibition?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the Lancet publish a study on Platelet Receptor Inhibition?. ### Response: 1999.


Instruction: Receptor Inhibition in Ischemic Syndrome Management. Lancet. 1999;354:1757–62.

Output: PRISM Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Receptor Inhibition in Ischemic Syndrome Management. Lancet. 1999;354:1757–62.. ### Response: PRISM Study Investigators.


Instruction: What was associated with improved perfusion images and increased exercise duration?

Output: Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with improved perfusion images and increased exercise duration?. ### Response: Treatment.


Instruction: What percentage of patients immediately after the last EECP treatment reported improvement of 1 Canadian Cardiovascular Society angina class?

Output: 81%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients immediately after the last EECP treatment reported improvement of 1 Canadian Cardiovascular Society angina class?. ### Response: 81%.


Instruction: Improvements in health-related quality of life have also been reported with what?

Output: EECP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Improvements in health-related quality of life have also been reported with what?. ### Response: EECP.


Instruction: What have been reported with EECP but there is limited evidence with which to determine the duration of the health-related benefits of treatment?

Output: Improvements in health-related quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have been reported with EECP but there is limited evidence with which to determine the duration of the health-related benefits of treatment?. ### Response: Improvements in health-related quality of life.


Instruction: Existing data largely from uncontrolled stud-ies suggest a benefit from what?

Output: EECP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Existing data largely from uncontrolled stud-ies suggest a benefit from what?. ### Response: EECP.


Instruction: What are patients with angina refractory to other therapy?

Output: EECP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with angina refractory to other therapy?. ### Response: EECP.


Instruction: What is needed to better define the role of EECP in patients with SIHD?

Output: CTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to better define the role of EECP in patients with SIHD?. ### Response: CTs.


Instruction: What remains unchanged from the 2012 guideline?

Output: the recommendation about EECP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains unchanged from the 2012 guideline?. ### Response: the recommendation about EECP.


Instruction: What did the 2012 guideline recommend?

Output: enhanced external counterpulsation and SIHD, stable ischemic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2012 guideline recommend?. ### Response: enhanced external counterpulsation and SIHD, stable ischemic heart disease.


Instruction: What is another word for CAD revascularization?

Output: Revascularization to Improve Survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another word for CAD revascularization?. ### Response: Revascularization to Improve Survival.


Instruction: Where can you find additional evidence?

Output: well-designed RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find additional evidence?. ### Response: well-designed RCTs.


Instruction: How many studies have been published comparing CABG and DES implantation?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have been published comparing CABG and DES implantation?. ### Response: 10.


Instruction: How long did most of the studies have follow-up periods?

Output: 12 to 24 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did most of the studies have follow-up periods?. ### Response: 12 to 24 months.


Instruction: In a meta-analysis of 24 268 patients with multivessel CAD treated with CABG or DES, how many patients were treated with DES or CABG?

Output: 80 the incidences of death and MI were similar for the 2 procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a meta-analysis of 24 268 patients with multivessel CAD treated with CABG or DES, how many patients were treated with DES or CABG?. ### Response: 80 the incidences of death and MI were similar for the 2 procedures.


Instruction: How many patients with multivessel CAD were treated with CABG or DES?

Output: 24 268

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with multivessel CAD were treated with CABG or DES?. ### Response: 24 268.


Instruction: What were the incidences of death and MI for the 2 procedures?

Output: similar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the incidences of death and MI for the 2 procedures?. ### Response: similar.


Instruction: How much higher was the frequency with which repeat revascularization was performed after DES implantation?

Output: 4 times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was the frequency with which repeat revascularization was performed after DES implantation?. ### Response: 4 times.


Instruction: How many large RCTs have been published?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many large RCTs have been published?. ### Response: 1.


Instruction: What is not recommended with the intent of improving symptoms or reducing cardiovascular risk in patients with SIHD?

Output: Chelation therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended with the intent of improving symptoms or reducing cardiovascular risk in patients with SIHD?. ### Response: Chelation therapy.


Instruction: What is uncertain about chelation therapy for reducing cardiovascular events in patients with SIHD?

Output: The usefulness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uncertain about chelation therapy for reducing cardiovascular events in patients with SIHD?. ### Response: The usefulness.


Instruction: What was the Class of Recommendation from III: No Benefit to IIb and Level of Evidence?

Output: C to B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Class of Recommendation from III: No Benefit to IIb and Level of Evidence?. ### Response: C to B.


Instruction: What indicates stable ischemic heart disease?

Output: EECP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates stable ischemic heart disease?. ### Response: EECP.


Instruction: What may be considered for relief of refractory angina?

Output: EECP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for relief of refractory angina?. ### Response: EECP.


Instruction: What may be considered for relief of refractory angina in patients with SIHD?

Output: EECP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for relief of refractory angina in patients with SIHD?. ### Response: EECP.


Instruction: What does EECP indicate enhanced external counterpulsation?

Output: SIHD, stable ischemic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does EECP indicate enhanced external counterpulsation?. ### Response: SIHD, stable ischemic heart disease.


Instruction: What is stable ischemic heart disease?

Output: SIHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stable ischemic heart disease?. ### Response: SIHD.


Instruction: When was this publication released?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication released?. ### Response: May 1, 2023.


Instruction: What is the date of this publication?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the date of this publication?. ### Response: May 1, 2023.


Instruction: What are patients who require long-term or indefinite anticoagulation at risk for?

Output: recurrent VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients who require long-term or indefinite anticoagulation at risk for?. ### Response: recurrent VTE.


Instruction: What is a value placed on outcomes related to preventio n of mortality?

Output: greater

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a value placed on outcomes related to preventio n of mortality?. ### Response: greater.


Instruction: What is DVT?

Output: deep veinthrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DVT?. ### Response: deep veinthrombosis.


Instruction: What was the impact of recommendations on measures of anticoagulation control, medication adherence, and convenience of therapy for patients?

Output: importance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the impact of recommendations on measures of anticoagulation control, medication adherence, and convenience of therapy for patients?. ### Response: importance.


Instruction: What does the ASH guideline include for patients with creatinine clearance of $50 mL/min receivingDOAC therapy for treatment of VTE?

Output: renal function monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ASH guideline include for patients with creatinine clearance of $50 mL/min receivingDOAC therapy for treatment of VTE?. ### Response: renal function monitoring.


Instruction: What do the recommendations take into consideration?

Output: cost and cost-effectiveness, impact on equity, acceptability, and feasibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the recommendations take into consideration?. ### Response: cost and cost-effectiveness, impact on equity, acceptability, and feasibility.


Instruction: What does the ASH guideline include every 6 to 12 months?

Output: renal function monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ASH guideline include every 6 to 12 months?. ### Response: renal function monitoring.


Instruction: What is the ungraded good practice statement for patients with creatinine clearance of,50 mL/min receivingDOAC therapy for treatment of VTE?

Output: good practicestatement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ungraded good practice statement for patients with creatinine clearance of,50 mL/min receivingDOAC therapy for treatment of VTE?. ### Response: good practicestatement.


Instruction: How often is renal function monitored?

Output: every6 to 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often is renal function monitored?. ### Response: every6 to 12 months.


Instruction: What is the purpose of these guidelines?

Output: to improve patient-important outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of these guidelines?. ### Response: to improve patient-important outcomes.


Instruction: What is another aspect of VTE treatment addressed in other guidelines?

Output: choice and duration of anticoagulant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another aspect of VTE treatment addressed in other guidelines?. ### Response: choice and duration of anticoagulant.


Instruction: What are recommendations focus on commonly used anticoagulant medications?

Output: UFH, LMWH, fondaparinux, VKA, and the DOACsapixaban, dabigatran, edoxaban, and rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are recommendations focus on commonly used anticoagulant medications?. ### Response: UFH, LMWH, fondaparinux, VKA, and the DOACsapixaban, dabigatran, edoxaban, and rivaroxaban.


Instruction: What are the most commonly used anticoagulant medications?

Output: UFH, LMWH, fondaparinux, VKA, and the DOACsapixaban, dabigatran, edoxaban, and rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the most commonly used anticoagulant medications?. ### Response: UFH, LMWH, fondaparinux, VKA, and the DOACsapixaban, dabigatran, edoxaban, and rivaroxaban.


Instruction: What was not available during panel deliberations and is not currentlyapproved for treatment of VTE?

Output: betrixaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not available during panel deliberations and is not currentlyapproved for treatment of VTE?. ### Response: betrixaban.


Instruction: What are the specific objectives of the recommendations?

Output: to improve patient-important outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the specific objectives of the recommendations?. ### Response: to improve patient-important outcomes.


Instruction: What did the panel consider as a surrogate for bleedingand thrombosis?

Output: time inthe therapeutic INR range (TTR)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the panel consider as a surrogate for bleedingand thrombosis?. ### Response: time inthe therapeutic INR range (TTR).


Instruction: What type of thrombosis was considered for all recommendations by the panel?

Output: deep veinthrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of thrombosis was considered for all recommendations by the panel?. ### Response: deep veinthrombosis.


Instruction: What was the target audience for recommendations?

Output: patients,physicians, other clinicians, and decision-makers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the target audience for recommendations?. ### Response: patients,physicians, other clinicians, and decision-makers.


Instruction: Who were the panel's target audience?

Output: patients,physicians, other clinicians, and decision-makers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were the panel's target audience?. ### Response: patients,physicians, other clinicians, and decision-makers.


Instruction: What is an area in need of further investigation?

Output: CMR,47,48 and there are insufficient data on the relationship between LV volumes and outcomes of patients with AR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an area in need of further investigation?. ### Response: CMR,47,48 and there are insufficient data on the relationship between LV volumes and outcomes of patients with AR.


Instruction: What are two other markers of LV dysfunction and re-modeling that require additional clinical outcome studies?

Output: global longitudinal strain and circu-lation biomarkers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two other markers of LV dysfunction and re-modeling that require additional clinical outcome studies?. ### Response: global longitudinal strain and circu-lation biomarkers.


Instruction: What biomarkers require additional clinical outcome studies?

Output: global longitudinal strain and circu-lation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What biomarkers require additional clinical outcome studies?. ### Response: global longitudinal strain and circu-lation.


Instruction: Symptoms are an important indication for what in patients with chronic severe AR?

Output: AVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Symptoms are an important indication for what in patients with chronic severe AR?. ### Response: AVR.


Instruction: What is the most important aspect of the clinical evaluation?

Output: LV systolic function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most important aspect of the clinical evaluation?. ### Response: LV systolic function.


Instruction: What do patients with chronic severe AR have a high risk of doing if AVR is not performed?

Output: death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients with chronic severe AR have a high risk of doing if AVR is not performed?. ### Response: death.


Instruction: What is related to the severity of preoperative symptoms, assessed either subjectively or objectively?

Output: survival and functional status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is related to the severity of preoperative symptoms, assessed either subjectively or objectively?. ### Response: survival and functional status.


Instruction: What is an important determi-nant of survival and functional status after AVR?

Output: LV systolic function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important determi-nant of survival and functional status after AVR?. ### Response: LV systolic function.


Instruction: What can be assessed either subjectively or objectively with exercise testing?

Output: survival and functional status after AVR are related to the severity of preoperative symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be assessed either subjectively or objectively with exercise testing?. ### Response: survival and functional status after AVR are related to the severity of preoperative symptoms.


Instruction: What is optimal when surgery is performed before LVEF decreases below 55%?

Output: Outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is optimal when surgery is performed before LVEF decreases below 55%?. ### Response: Outcomes.


Instruction: In asymptomatic patients with LV systolic dysfunction, postoperative out-comes are better if what is done before onset of symptoms?

Output: AVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In asymptomatic patients with LV systolic dysfunction, postoperative out-comes are better if what is done before onset of symptoms?. ### Response: AVR.


Instruction: Patients with chronic severe AR may be referred for what other types of cardiac surgery?

Output: CABG, mitral valve surgery, or surgery for correction of dilation of the aortic root or ascending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with chronic severe AR may be referred for what other types of cardiac surgery?. ### Response: CABG, mitral valve surgery, or surgery for correction of dilation of the aortic root or ascending aorta.


Instruction: What are some other types of cardiac surgery?

Output: CABG, mitral valve surgery, or surgery for correction of dilation of the aortic root or ascending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some other types of cardiac surgery?. ### Response: CABG, mitral valve surgery, or surgery for correction of dilation of the aortic root or ascending aorta.


Instruction: What can AVR prevent in AR patients?

Output: hemo-dynamic consequences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can AVR prevent in AR patients?. ### Response: hemo-dynamic consequences.


Instruction: What is a possible need for a second cardiac operation in the near future?

Output: AVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible need for a second cardiac operation in the near future?. ### Response: AVR.


Instruction: What may patients undergoing surgical repair or replacement of the aortic root or ascending Aorta be can-didates for?

Output: aortic valve–sparing procedures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients undergoing surgical repair or replacement of the aortic root or ascending Aorta be can-didates for?. ### Response: aortic valve–sparing procedures.


Instruction: LVESD in patients with chronic AR reflects the severity of what?

Output: LV volume overload

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LVESD in patients with chronic AR reflects the severity of what?. ### Response: LV volume overload.


Instruction: What reflects both the severity of the LV volume overload and the degree of LV systolic shortening?

Output: LVESD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reflects both the severity of the LV volume overload and the degree of LV systolic shortening?. ### Response: LVESD.


Instruction: An elevated LVESD often reflects what?

Output: LV systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: An elevated LVESD often reflects what?. ### Response: LV systolic dysfunction.


Instruction: What is associated with LV remod-eling and an increased mortality rate after AVR?

Output: LV systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with LV remod-eling and an increased mortality rate after AVR?. ### Response: LV systolic dysfunction.


Instruction: Most studies have used unadjusted LVESD but indexing for body size is important?

Output: women or small patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most studies have used unadjusted LVESD but indexing for body size is important?. ### Response: women or small patients.


Instruction: What is important in women or small patients?

Output: indexing for body size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important in women or small patients?. ### Response: indexing for body size.


Instruction: What is the LVESD index threshold for optimal postoperative survival?

Output: 25 mm/m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LVESD index threshold for optimal postoperative survival?. ### Response: 25 mm/m2.


Instruction: What is needed for more outcome data and ide-ally an RCT?

Output: earlier intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed for more outcome data and ide-ally an RCT?. ### Response: earlier intervention.


Instruction: What group did Lees KR, Emberson J, Blackwell L, Bluhmki E, Davis SM, Donnan GA, Grotta JC, Kaste M, von Kummer R, Lansberg MG, et al represent?

Output: Stroke Thrombolysis Trialists’ Collaborators Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group did Lees KR, Emberson J, Blackwell L, Bluhmki E, Davis SM, Donnan GA, Grotta JC, Kaste M, von Kummer R, Lansberg MG, et al represent?. ### Response: Stroke Thrombolysis Trialists’ Collaborators Group.


Instruction: What was the pooled analysis of 9 studies of alteplase for acute stroke?

Output: Effects of alteplase for acute stroke on the distribution of functional out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the pooled analysis of 9 studies of alteplase for acute stroke?. ### Response: Effects of alteplase for acute stroke on the distribution of functional out-comes.


Instruction: What was the distribution of functional out-comes: a pooled analysis of 9 trials?

Output: Effects of alteplase for acute stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the distribution of functional out-comes: a pooled analysis of 9 trials?. ### Response: Effects of alteplase for acute stroke.


Instruction: Stroke. 2016;47:2373–2379. doi: 10.1161/STROKEAHA.116.013644 79.

Output: Stroke Thrombolysis Trialists’ Collaborators Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stroke. 2016;47:2373–2379. doi: 10.1161/STROKEAHA.116.013644 79.. ### Response: Stroke Thrombolysis Trialists’ Collaborators Group.


Instruction: What does Streamlining door to recanalization processes in endovascular stroke therapy do?

Output: Effects of alteplase for acute stroke on the distribution of functional out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Streamlining door to recanalization processes in endovascular stroke therapy do?. ### Response: Effects of alteplase for acute stroke on the distribution of functional out-comes.


Instruction: What is the goal of recanalization processes in endovascular stroke therapy?

Output: Streamlining door

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of recanalization processes in endovascular stroke therapy?. ### Response: Streamlining door.


Instruction: What are some of the reasons acute stroke patients aren't receiving IV tPA?

Output: Streamlining door to recanalization processes in endovascular stroke therapy. J Neurointerv Surg. 2017;9:340–345. doi: 10.1136/neurintsurg-2016-012324 80. Messe SR, Khatri P, Reeves MJ, Smith EE, Saver JL, Bhatt DL, Grau-Sepulveda MV , Cox M, Peterson ED, Fonarow GC, et al. Why are acute ischemic stroke patients not receiving IV tPA? Results from a na-tional registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the reasons acute stroke patients aren't receiving IV tPA?. ### Response: Streamlining door to recanalization processes in endovascular stroke therapy. J Neurointerv Surg. 2017;9:340–345. doi: 10.1136/neurintsurg-2016-012324 80. Messe SR, Khatri P, Reeves MJ, Smith EE, Saver JL, Bhatt DL, Grau-Sepulveda MV , Cox M, Peterson ED, Fonarow GC, et al. Why are acute ischemic stroke patients not receiving IV tPA? Results from a na-tional registry.


Instruction: What is not being given to acute ischemic stroke patients?

Output: IV tPA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not being given to acute ischemic stroke patients?. ### Response: IV tPA.


Instruction: What are the results from a na-tional registry?

Output: Why are acute ischemic stroke patients not receiving IV tPA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results from a na-tional registry?. ### Response: Why are acute ischemic stroke patients not receiving IV tPA.


Instruction: What are the primary determi-nants of cardiac structure and function?

Output: Physical forces (pressure and flow)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the primary determi-nants of cardiac structure and function?. ### Response: Physical forces (pressure and flow).


Instruction: When SBP is elevated, both LV output impedance and intramyocardial wall tension increase?

Output: increased myocardial oxygen demand

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When SBP is elevated, both LV output impedance and intramyocardial wall tension increase?. ### Response: increased myocardial oxygen demand.


Instruction: What is the result of intramyocardial wall tension increase?

Output: increased myocardial oxygen demand

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the result of intramyocardial wall tension increase?. ### Response: increased myocardial oxygen demand.


Instruction: What is usually attributable to inappropriately high aortic impedance?

Output: wide pulse pressure and systolic hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is usually attributable to inappropriately high aortic impedance?. ### Response: wide pulse pressure and systolic hypertension.


Instruction: Aging is associated with thinning and fragmentation of vascular elastin and increased collagen deposition, a degenerative process that causes increased arterial stiffness (reduction of elasticity) and an elevation in what?

Output: SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aging is associated with thinning and fragmentation of vascular elastin and increased collagen deposition, a degenerative process that causes increased arterial stiffness (reduction of elasticity) and an elevation in what?. ### Response: SBP.


Instruction: AHAjournals.org by on what date?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AHAjournals.org by on what date?. ### Response: May 3, 2023.


Instruction: What does the widening of the pulse pressure mean?

Output: increased arterial stiffness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the widening of the pulse pressure mean?. ### Response: increased arterial stiffness.


Instruction: When was the download of the report done?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the download of the report done?. ### Response: May 3, 2023.


Instruction: How long after PCI was provisional GP IIb/IIIa inhibitor use allowed before angiography in the deferred group for severebreakthrough ischemia?

Output: 2 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after PCI was provisional GP IIb/IIIa inhibitor use allowed before angiography in the deferred group for severebreakthrough ischemia?. ### Response: 2 hours.