Instruction: What does the 3C -HF score predict?

Output: heart failure outcome from cardiac and comorbid conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the 3C -HF score predict?. ### Response: heart failure outcome from cardiac and comorbid conditions.


Instruction: What is the name of the score used to predict heart failure outcome?

Output: 3C -HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the score used to predict heart failure outcome?. ### Response: 3C -HF.


Instruction: When was the International Journal of Cardiology published?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the International Journal of Cardiology published?. ### Response: 2013.


Instruction: What is the name of the randomized controlled trial of mobile phone based telemonitoring for heart failure management?

Output: NorthStar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial of mobile phone based telemonitoring for heart failure management?. ### Response: NorthStar.


Instruction: When was the Journal of Medical Internet Research published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Journal of Medical Internet Research published?. ### Response: 2012.


Instruction: What is the prognostic importance of impaired systolic function in heart failure with preserved ejection fraction and the impact of spironolactone?

Output: 402 -14 307

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognostic importance of impaired systolic function in heart failure with preserved ejection fraction and the impact of spironolactone?. ### Response: 402 -14 307.


Instruction: Circulation. 2015; 132(5):402 -14 307.

Output: Prognostic importance o f impaired systolic function in heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2015; 132(5):402 -14 307.. ### Response: Prognostic importance o f impaired systolic function in heart failure.


Instruction: What is the prognosis of heart failure with preserved ejection fraction?

Output: impaired systolic function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prognosis of heart failure with preserved ejection fraction?. ### Response: impaired systolic function.


Instruction: What was the echocardiographic study of?

Output: Treatment of Preserved Cardiac Function Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the echocardiographic study of?. ### Response: Treatment of Preserved Cardiac Function Heart Failure.


Instruction: What was observed between the treatment effect and type of ACS?

Output: reduction in theprimary efficacy endpoint among NSTEMI patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was observed between the treatment effect and type of ACS?. ### Response: reduction in theprimary efficacy endpoint among NSTEMI patients.


Instruction: What was associated with a significant reduction in theprimary efficacy endpoint among NSTEMI patients?

Output: ti-cagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a significant reduction in theprimary efficacy endpoint among NSTEMI patients?. ### Response: ti-cagrelor.


Instruction: What percentage of UA patients did not take ticagrelor?

Output: 8.6%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of UA patients did not take ticagrelor?. ### Response: 8.6%.


Instruction: What was the HR of the UA patient?

Output: 0.96

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of the UA patient?. ### Response: 0.96.


Instruction: How long did the benefits of the drug last?

Output: up to 360days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the benefits of the drug last?. ### Response: up to 360days.


Instruction: The benefits of what drug were evident regardless of pre-treatment?

Output: ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The benefits of what drug were evident regardless of pre-treatment?. ### Response: ticagrelor.


Instruction: What was associated with a 1.4% absolute reduction in all-cause mortality?

Output: ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a 1.4% absolute reduction in all-cause mortality?. ### Response: ticagrelor.


Instruction: What did ticagrelor be associated with?

Output: a 1.4% absolute reduction in all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did ticagrelor be associated with?. ### Response: a 1.4% absolute reduction in all-cause mortality.


Instruction: What was the HR of the ticagre-lor group versus the clopidogrel group?

Output: 7.4% versus 6.0%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of the ticagre-lor group versus the clopidogrel group?. ### Response: 7.4% versus 6.0%;.


Instruction: What is the primary safety endpoint of the PLATO study?

Output: composite of major life-threateningand other major bleeding events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary safety endpoint of the PLATO study?. ### Response: composite of major life-threateningand other major bleeding events.


Instruction: Which group had no significant differences in rates of major bleeding?

Output: ticagre-lor and clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which group had no significant differences in rates of major bleeding?. ### Response: ticagre-lor and clopidogrel.


Instruction: What percentage of patients underwent CABG?

Output: 1.90%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients underwent CABG?. ### Response: 1.90%;.


Instruction: What was the rate of majorbleeding in patients undergoing CABG versus 7.7%?

Output: 7.9%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the rate of majorbleeding in patients undergoing CABG versus 7.7%?. ### Response: 7.9%.


Instruction: How long were clopidogreland ticagrelor discontinued before the procedure?

Output: 5days and 24 to 72 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long were clopidogreland ticagrelor discontinued before the procedure?. ### Response: 5days and 24 to 72 hours.


Instruction: What was associated with a higher rate of non-CABG-related major bleeding?

Output: Ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a higher rate of non-CABG-related major bleeding?. ### Response: Ticagrelor.


Instruction: How much higher was the incidence of dyspnea?

Output: 13.8% versus 7.8%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was the incidence of dyspnea?. ### Response: 13.8% versus 7.8%;.


Instruction: What is the rate of ventricular pauses in the first week?

Output: /H113503 seconds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rate of ventricular pauses in the first week?. ### Response: /H113503 seconds.


Instruction: How much is the incidence ofdyspnea versus 7.8%?

Output: 13.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much is the incidence ofdyspnea versus 7.8%?. ### Response: 13.8%.


Instruction: What percentage of patients had a history of nonhemorrhagic stroke?

Output: /H110214%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients had a history of nonhemorrhagic stroke?. ### Response: /H110214%.


Instruction: What was excluded from the PLATO study?

Output: Patients with ahistory of bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was excluded from the PLATO study?. ### Response: Patients with ahistory of bleeding.


Instruction: What percentage of patients had a prior history of nonhemorrhagic stroke?

Output: /H110214%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients had a prior history of nonhemorrhagic stroke?. ### Response: /H110214%.


Instruction: The efficacy and safety of ticagrelor in patients with prior tran-sient ischemic attack or stroke were not reported in PLATO?

Output: 9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The efficacy and safety of ticagrelor in patients with prior tran-sient ischemic attack or stroke were not reported in PLATO?. ### Response: 9.


Instruction: What was performed for the 5216 patients inPLATO admitted?

Output: A separate analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was performed for the 5216 patients inPLATO admitted?. ### Response: A separate analysis.


Instruction: How many patients in thePLATO study were admitted with ACS and prespecified as planned fornoninvasive management?

Output: 5216

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients in thePLATO study were admitted with ACS and prespecified as planned fornoninvasive management?. ### Response: 5216.


Instruction: What is not effective as a secondary prevention measure for cardiovascular disease?

Output: high-dose B vitamins and folic acid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not effective as a secondary prevention measure for cardiovascular disease?. ### Response: high-dose B vitamins and folic acid.


Instruction: How many randomized, controlled trials with nearly 300 000 participants showed no benefit of vitamin and antioxidant supplementation in reducing the risk of major cardiovascular events?

Output: 50

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized, controlled trials with nearly 300 000 participants showed no benefit of vitamin and antioxidant supplementation in reducing the risk of major cardiovascular events?. ### Response: 50.


Instruction: What is one way to reduce the risk of major cardiovascular events?

Output: vitamin supplementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one way to reduce the risk of major cardiovascular events?. ### Response: vitamin supplementation.


Instruction: Undergoing cardiac surgery leads to considerable stress on the body, which plays a key factor in what?

Output: determining outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Undergoing cardiac surgery leads to considerable stress on the body, which plays a key factor in what?. ### Response: determining outcome.


Instruction: Along with weight loss and protein catabolism, cardiac surgery is associated with numerous derangements in what area of the body?

Output: stored vitamin and other metabolite levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Along with weight loss and protein catabolism, cardiac surgery is associated with numerous derangements in what area of the body?. ### Response: stored vitamin and other metabolite levels.


Instruction: What is often associated with numerous derangements in stored vitamin and other metabolite levels?

Output: cardiac sur -gery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often associated with numerous derangements in stored vitamin and other metabolite levels?. ### Response: cardiac sur -gery.


Instruction: What is accompanied by a significant acute phase and inflammatory response?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is accompanied by a significant acute phase and inflammatory response?. ### Response: CABG.


Instruction: What are impor -tant antioxidants that aid in wound healing?

Output: vitamin A and vitamin C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are impor -tant antioxidants that aid in wound healing?. ### Response: vitamin A and vitamin C.


Instruction: What did Schindler and colleagues study?

Output: serial plasma samples before, during, and up to 48 hours after surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Schindler and colleagues study?. ### Response: serial plasma samples before, during, and up to 48 hours after surgery.


Instruction: What did Schindler and colleagues study before, during, and up to 48 hours after surgery?

Output: serial plasma samples

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Schindler and colleagues study before, during, and up to 48 hours after surgery?. ### Response: serial plasma samples.


Instruction: Vitamin A and vitamin E levels decreased significantly after what procedure?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Vitamin A and vitamin E levels decreased significantly after what procedure?. ### Response: CABG.


Instruction: What are part of the body's first line of defense?

Output: homocysteine and folic acid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are part of the body's first line of defense?. ### Response: homocysteine and folic acid.


Instruction: Other studies have documented decreases in what vitamins?

Output: vitamin A and vitamin C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Other studies have documented decreases in what vitamins?. ### Response: vitamin A and vitamin C.


Instruction: Vitamins B6, B12, and thiamine are essential for what?

Output: mitochondrial function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Vitamins B6, B12, and thiamine are essential for what?. ### Response: mitochondrial function.


Instruction: Vitamin D levels have been shown to be important predictors of what after cardiac surgery?

Output: outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Vitamin D levels have been shown to be important predictors of what after cardiac surgery?. ### Response: outcome.


Instruction: What percentage of patients recovering from cardiac surgery had deficient 25(OH)D values?

Output: 38.0%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients recovering from cardiac surgery had deficient 25(OH)D values?. ### Response: 38.0%.


Instruction: How much of the population had deficient 25(OH)D values?

Output: 38.0%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the population had deficient 25(OH)D values?. ### Response: 38.0%.


Instruction: What was the value of 30 nmol/L?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the value of 30 nmol/L?. ### Response: (<.


Instruction: In multivariable-adjusted models, what was associated with a higher risk of major adverse cardiac events?

Output: a low 25(OH)D value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In multivariable-adjusted models, what was associated with a higher risk of major adverse cardiac events?. ### Response: a low 25(OH)D value.


Instruction: How long was the duration of mechanical ventilatory support?

Output: longer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the duration of mechanical ventilatory support?. ### Response: longer.


Instruction: What is a possible benefit of vitamin supplementation?

Output: wound healing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible benefit of vitamin supplementation?. ### Response: wound healing.


Instruction: What are the two types of mortality?

Output: 6- and 12-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two types of mortality?. ### Response: 6- and 12-month.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 53 of 127 moderate intake of low-fat dairy products?

Output: June 2020   Page 53 of 127 moderate intake of low -fat dairy products, and a low -to-moderate red wine intake for those who drink alcohol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 53 of 127 moderate intake of low-fat dairy products?. ### Response: June 2020   Page 53 of 127 moderate intake of low -fat dairy products, and a low -to-moderate red wine intake for those who drink alcohol.


Instruction: What is a low-to-moderate red wine intake for those who drink alcohol?

Output: low -fat dairy products

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a low-to-moderate red wine intake for those who drink alcohol?. ### Response: low -fat dairy products.


Instruction: What did evidence suggest improved lipid outcomes when a registered dietitian provid ed?

Output: medical nutrition therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did evidence suggest improved lipid outcomes when a registered dietitian provid ed?. ### Response: medical nutrition therapy.


Instruction: What did the Work Group systematically review related to this recommendation?

Output: evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group systematically review related to this recommendation?. ### Response: evidence.


Instruction: The Wor k Group’s confidence in this recommendation was what?

Output: low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Wor k Group’s confidence in this recommendation was what?. ### Response: low.


Instruction: The Wor k Group's confidence in the quality of the evidence wa s low.

Output: diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Wor k Group's confidence in the quality of the evidence wa s low.. ### Response: diet.


Instruction: With respect to diet, patient values and preferences vary largely.

Output: observational data indicate  associations between regular physical activity and the main components of lipids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: With respect to diet, patient values and preferences vary largely.. ### Response: observational data indicate  associations between regular physical activity and the main components of lipids.


Instruction: What did the Work Group decide upon?

Output: a “Weak for” recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group decide upon?. ### Response: a “Weak for” recommendation.


Instruction: What is needed to evaluate the effectiveness of replacing saturate d fat with unsaturated fats to determine the effect on mortality and morbidity?

Output: Well- controlled RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to evaluate the effectiveness of replacing saturate d fat with unsaturated fats to determine the effect on mortality and morbidity?. ### Response: Well- controlled RCTs.


Instruction: What is the focus of Recommendation 26?

Output: primary and secondary prevention of cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of Recommendation 26?. ### Response: primary and secondary prevention of cardiovascular disease.


Instruction: What do we suggest for primary and secondary prevention of cardiovascular disease?

Output: regular aerobic physical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest for primary and secondary prevention of cardiovascular disease?. ### Response: regular aerobic physical.


Instruction: What are the benefits of regular physical activity associated with?

Output: many health domains

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the benefits of regular physical activity associated with?. ### Response: many health domains.


Instruction: What do clinicians often cite when advocating for lifestyle change to their patients?

Output: its effects on CV risk reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do clinicians often cite when advocating for lifestyle change to their patients?. ### Response: its effects on CV risk reduction.


Instruction: The biological plausibility that physical activity could improve CV outcomes by positively altering what has been well established?

Output: lipid profiles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The biological plausibility that physical activity could improve CV outcomes by positively altering what has been well established?. ### Response: lipid profiles.


Instruction: What has been well established?

Output: The biological plausibility that physical activity could improve CV outcomes by positively altering lipid profiles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been well established?. ### Response: The biological plausibility that physical activity could improve CV outcomes by positively altering lipid profiles.


Instruction: Lipids and their various subtypes are established independent CV risk factors and observational data indicate associations between regular physical activity and the main components of lipids?

Output: reductions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Lipids and their various subtypes are established independent CV risk factors and observational data indicate associations between regular physical activity and the main components of lipids?. ### Response: reductions.


Instruction: Reduces in TC and LDL and increases in HDL are examples of what?

Output: observational data indicate  associations between regular physical activity and the main components of lipids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Reduces in TC and LDL and increases in HDL are examples of what?. ### Response: observational data indicate  associations between regular physical activity and the main components of lipids.


Instruction: What is the association between physical activity and lower CVD risk?

Output: Whether these changes in lipids are mediating  the association between physical activity and lower CVD risk is unknown

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between physical activity and lower CVD risk?. ### Response: Whether these changes in lipids are mediating  the association between physical activity and lower CVD risk is unknown.


Instruction: What is a plausible connection?

Output: biological

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a plausible connection?. ### Response: biological.


Instruction: Dyslipidemia is Defined by Risk for Cardiovascular Disease?

Output: CV  risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dyslipidemia is Defined by Risk for Cardiovascular Disease?. ### Response: CV  risk.


Instruction: What is the traditional definition of dyslipidemia based on?

Output: lipid levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the traditional definition of dyslipidemia based on?. ### Response: lipid levels.


Instruction: What is Defined by Risk for Cardiovascular Disease?

Output: Dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Defined by Risk for Cardiovascular Disease?. ### Response: Dyslipidemia.


Instruction: The broader definition of dyslipidemia and the biological plausibility connection warrant consideration of physical activity as a strategy in managing what?

Output: dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The broader definition of dyslipidemia and the biological plausibility connection warrant consideration of physical activity as a strategy in managing what?. ### Response: dyslipidemia.


Instruction: What did the Work Group recognize that both the 2008 Physical Activity Guidelines for Americans (PAGA) and 2014 referenced?

Output: VA/DoD Dyslipidemia CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group recognize that both the 2008 Physical Activity Guidelines for Americans (PAGA) and 2014 referenced?. ### Response: VA/DoD Dyslipidemia CPG.


Instruction: What is the acronym for Activity Guidelines for Americans?

Output: PAGA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Activity Guidelines for Americans?. ### Response: PAGA.


Instruction: How many minutes of moderate intensity aerobic exercise per week are recommended per PAGA?

Output: 150

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many minutes of moderate intensity aerobic exercise per week are recommended per PAGA?. ### Response: 150.


Instruction: What type of trial data is lacking in the PAGA guideline?

Output: randomized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of trial data is lacking in the PAGA guideline?. ### Response: randomized.


Instruction: What is lacking in the CPG?

Output: randomized trial data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lacking in the CPG?. ### Response: randomized trial data.


Instruction: What did the systematic evidence re view yield?

Output: an

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the systematic evidence re view yield?. ### Response: an.


Instruction: What is the acronym for the American Heart Association Stroke Council?

Output: American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American Heart Association Stroke Council?. ### Response: American Stroke Association.


Instruction: What are the acronyms for the Interdisciplinary Council on Peripheral Vascular Disease and Council on Cardiovascular Radiology and Intervention?

Output: Council on Epidemiology and Prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the acronyms for the Interdisciplinary Council on Peripheral Vascular Disease and Council on Cardiovascular Radiology and Intervention?. ### Response: Council on Epidemiology and Prevention.


Instruction: What is the name of the policy statement from the American Heart Association regarding telemedicine in stroke systems of care?

Output: Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guide-line

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the policy statement from the American Heart Association regarding telemedicine in stroke systems of care?. ### Response: Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guide-line.


Instruction: How many strokes are there in 2009?

Output: 40:2635–2660

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes are there in 2009?. ### Response: 40:2635–2660.


Instruction: What are the numbers of strokes in 2009 in the US?

Output: 109.192361

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the numbers of strokes in 2009 in the US?. ### Response: 109.192361.


Instruction: Who is responsible for the implementation of telemedical care in stroke?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is responsible for the implementation of telemedical care in stroke?. ### Response: American Heart Association.


Instruction: Who is on behalf of the American Heart Association Advocacy Coordinating Committee?

Output: Alexander DN, Crocco TJ, Demaerschalk BM, Derdeyn CP, Goldstein LB, Jauch EC, Mayer SA, Meltzer NM, et al;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is on behalf of the American Heart Association Advocacy Coordinating Committee?. ### Response: Alexander DN, Crocco TJ, Demaerschalk BM, Derdeyn CP, Goldstein LB, Jauch EC, Mayer SA, Meltzer NM, et al;.


Instruction: Interactions within stroke systems of care: a policy statement from whom?

Output: American Heart Association/American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Interactions within stroke systems of care: a policy statement from whom?. ### Response: American Heart Association/American Stroke Association.


Instruction: Stroke. 2013;44:2961–84. doi: 10.1161/STR.0b013e3182a6d2b2?

Output: Interactions within stroke systems of care: a policy statement from the American Heart Association/American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stroke. 2013;44:2961–84. doi: 10.1161/STR.0b013e3182a6d2b2?. ### Response: Interactions within stroke systems of care: a policy statement from the American Heart Association/American Stroke Association.


Instruction: What is the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation?

Output: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation?. ### Response: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.


Instruction: What does the Association Task Force on Practice Guidelines and the Heart Rhythm Society do?

Output: a report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Association Task Force on Practice Guidelines and the Heart Rhythm Society do?. ### Response: a report.


Instruction: What does Circulation. 2014;130:2071–2104.

Output: AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Circulation. 2014;130:2071–2104.. ### Response: AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.


Instruction: Who is on behalf of the American Heart Association Stroke Council?

Output: th KN, Zahuranec DB, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is on behalf of the American Heart Association Stroke Council?. ### Response: th KN, Zahuranec DB, et al.


Instruction: What are the recommendations for the management of cerebral and cerebellar infarction with swell-ing?

Output: a statement for healthcare professionals from the American Heart Association/American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for the management of cerebral and cerebellar infarction with swell-ing?. ### Response: a statement for healthcare professionals from the American Heart Association/American Stroke Association.


Instruction: On behalf of the American Heart Association, Council on Cardiovascular and Stroke Nursing, and Council on Clinical Cardiology, what is a state-ment for healthcare professionals?

Output: Palliative and end-of-life care in stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On behalf of the American Heart Association, Council on Cardiovascular and Stroke Nursing, and Council on Clinical Cardiology, what is a state-ment for healthcare professionals?. ### Response: Palliative and end-of-life care in stroke.


Instruction: What is Palliative and end of life care in stroke?

Output: a state-ment for healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Palliative and end of life care in stroke?. ### Response: a state-ment for healthcare professionals.


Instruction: What is the name of the state-ment for healthcare professionals from the American Heart Association/American Stroke Association?

Output: Palliative and end-of-life care in stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the state-ment for healthcare professionals from the American Heart Association/American Stroke Association?. ### Response: Palliative and end-of-life care in stroke.


Instruction: When was stroke published?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was stroke published?. ### Response: 2013.


Instruction: How many strokes were there between 1887 and 1916?

Output: 45

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there between 1887 and 1916?. ### Response: 45.


Instruction: Along with Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and Council on Peripheral Vascular Disease, what group is on be-half of the American Heart Association?

Output: Stroke Council

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Along with Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and Council on Peripheral Vascular Disease, what group is on be-half of the American Heart Association?. ### Response: Stroke Council.


Instruction: What is the name of the group that provides guidelines for the prevention of stroke in patients with stroke and transient ischemic attack?

Output: American Heart Association/American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that provides guidelines for the prevention of stroke in patients with stroke and transient ischemic attack?. ### Response: American Heart Association/American Stroke Association.


Instruction: What is the name of the guide-line for healthcare professionals from the American Heart Association/American Stroke Association?

Output: Guidelines for the prevention of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guide-line for healthcare professionals from the American Heart Association/American Stroke Association?. ### Response: Guidelines for the prevention of stroke.


Instruction: When was the last time a guideline was published?

Output: January CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a guideline was published?. ### Response: January CT.


Instruction: What was the title of the 2014 guideline?

Output: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the 2014 guideline?. ### Response: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: Who wrote the guideline on behalf of healthcare professionals?

Output: American Heart Association Advocacy Coordinating Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the guideline on behalf of healthcare professionals?. ### Response: American Heart Association Advocacy Coordinating Committee.


Instruction: Disease Patients (ENRICHD) Randomized Trial. JAMA. 2003;289:3106–16.e440 Circulation December 18/25, 2012Downloaded from http://ahajournals.org by on what date?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Disease Patients (ENRICHD) Randomized Trial. JAMA. 2003;289:3106–16.e440 Circulation December 18/25, 2012Downloaded from http://ahajournals.org by on what date?. ### Response: May 1, 2023.


Instruction: What can be used to determine if a heparin –platelet anti-body test should be performed?

Output: Clinical scoring estimates that use a fall in plateletcount greater than 50% or a thrombotic event be-tween 5 and 14 days after a heparin exposure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to determine if a heparin –platelet anti-body test should be performed?. ### Response: Clinical scoring estimates that use a fall in plateletcount greater than 50% or a thrombotic event be-tween 5 and 14 days after a heparin exposure.


Instruction: What is HIT?

Output: heparin-induced thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HIT?. ### Response: heparin-induced thrombocytopenia.


Instruction: What is heparin-induced thrombocytopenia?

Output: HIT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heparin-induced thrombocytopenia?. ### Response: HIT.


Instruction: What can be beneficial in diagnosing patients with HIT who have a history of?

Output: anticoagulationwith bivalirudin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial in diagnosing patients with HIT who have a history of?. ### Response: anticoagulationwith bivalirudin.


Instruction: What is PF4 –heparin antibodytesting inconclusive for?

Output: HIT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PF4 –heparin antibodytesting inconclusive for?. ### Response: HIT.


Instruction: What is the level of evidence for HIT?

Output: C)/C15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for HIT?. ### Response: C)/C15.


Instruction: What is a reasonable treatment for patients with a diagnosis of HIT and needing CPB?

Output: anticoagulationwith bivalirudin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable treatment for patients with a diagnosis of HIT and needing CPB?. ### Response: anticoagulationwith bivalirudin.


Instruction: If a patient has a functional test orantigenic assay negative, what is the expectation that heparin anticoagulation therapy forCPB is likely to be?

Output: safe and effective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If a patient has a functional test orantigenic assay negative, what is the expectation that heparin anticoagulation therapy forCPB is likely to be?. ### Response: safe and effective.


Instruction: Anticoagulation with bivalirudin is a reasonable option for what?

Output: patients with a diagnosis of HIT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anticoagulation with bivalirudin is a reasonable option for what?. ### Response: patients with a diagnosis of HIT.


Instruction: In patients with signi ficant renal dysfunction who are seropositive for HIT and require urgent opera-tion requiring CPB, use of plasmapheresis, arga-troban, or heparin with antiplatelet agents (such as astirofiban, ilioprost) may be considered.

Output: may be considered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with signi ficant renal dysfunction who are seropositive for HIT and require urgent opera-tion requiring CPB, use of plasmapheresis, arga-troban, or heparin with antiplatelet agents (such as astirofiban, ilioprost) may be considered.. ### Response: may be considered.


Instruction: What are some agents that may be considered?

Output: astiroﬁban, ilioprost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some agents that may be considered?. ### Response: astiroﬁban, ilioprost.


Instruction: What are the chief contraindications to the use of heparin forCPB?

Output: a history of HIT and known hypersensitivity toheparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the chief contraindications to the use of heparin forCPB?. ### Response: a history of HIT and known hypersensitivity toheparin.


Instruction: How is HIT characterized?

Output: heparin –platelet anti-body test should be performed to diagnose heparin-induced thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is HIT characterized?. ### Response: heparin –platelet anti-body test should be performed to diagnose heparin-induced thrombocytopenia.


Instruction: What antibodies recognize PF4-heparin complexes?

Output: immunoglobulin G antibodies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What antibodies recognize PF4-heparin complexes?. ### Response: immunoglobulin G antibodies.


Instruction: What type of reactions can be caused by hypersensitivity reactions toheparine?

Output: type I, II, or IV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of reactions can be caused by hypersensitivity reactions toheparine?. ### Response: type I, II, or IV.


Instruction: Inpatients with or without thrombosis form what type of complex?

Output: PF4-heparin immune complex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inpatients with or without thrombosis form what type of complex?. ### Response: PF4-heparin immune complex.


Instruction: What is the basis for the clinical anti-genic assay for HIT?

Output: anti –PF4-heparin antibodies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the basis for the clinical anti-genic assay for HIT?. ### Response: anti –PF4-heparin antibodies.


Instruction: What percentage of surgical patients have PF4-heparin complexes after exposure?

Output: 30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of surgical patients have PF4-heparin complexes after exposure?. ### Response: 30%.


Instruction: How much lower is the incidence of HIT in surgical patients?

Output: 1% to 2%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much lower is the incidence of HIT in surgical patients?. ### Response: 1% to 2%).


Instruction: What percentage of HIT is much lower?

Output: 1% to 2%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of HIT is much lower?. ### Response: 1% to 2%).


Instruction: Patients who test positive for anti –PF4-heparin antibodies preoperatively appear to have a higher overall risk forcomplications and increased mortality after cardiacsurgery?

Output: % to 2%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients who test positive for anti –PF4-heparin antibodies preoperatively appear to have a higher overall risk forcomplications and increased mortality after cardiacsurgery?. ### Response: % to 2%).


Instruction: What is the 60- to 90-day amnestic period for HIT antibodies?

Output: postponing elective cardiac surgery inpatients with elevated PF4-heparin antibodies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 60- to 90-day amnestic period for HIT antibodies?. ### Response: postponing elective cardiac surgery inpatients with elevated PF4-heparin antibodies.


Instruction: What could postpone elective cardiac surgery inpatients with elevated PF4-heparin antibodies do?

Output: mitigate this avoidable risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could postpone elective cardiac surgery inpatients with elevated PF4-heparin antibodies do?. ### Response: mitigate this avoidable risk.


Instruction: What could mitigate the avoidable risk of HIT antibodies?

Output: postponing elective cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could mitigate the avoidable risk of HIT antibodies?. ### Response: postponing elective cardiac surgery.


Instruction: What are the outcomes most relevant to patients with AF?

Output: death, nonfatal stroke, systemicembolism, nonfatal major extracranial bleeding, and the burden andlifestyle limitations associated with outpatient antithrombotictherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes most relevant to patients with AF?. ### Response: death, nonfatal stroke, systemicembolism, nonfatal major extracranial bleeding, and the burden andlifestyle limitations associated with outpatient antithrombotictherapy.


Instruction: What is the burden andstyle limitations associated with outpatient antithrombotictherapy?

Output: lifestyle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the burden andstyle limitations associated with outpatient antithrombotictherapy?. ### Response: lifestyle.


Instruction: What was the principal outcome in most stroke prevention trials?

Output: safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the principal outcome in most stroke prevention trials?. ### Response: safety.


Instruction: What was considered the principal safety outcomein most stroke trials? Intracranialbleeding was considered what type of bleeding?

Output: Major bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered the principal safety outcomein most stroke trials? Intracranialbleeding was considered what type of bleeding?. ### Response: Major bleeding.


Instruction: What is the most severe and disabling form of anticoagulant-related bleeding?

Output: intracranialbleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most severe and disabling form of anticoagulant-related bleeding?. ### Response: intracranialbleeding.


Instruction: What was the last formal literature search performed for the American College ofChest Physicians Evidence-Based Clinical Practice Guidelines?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the last formal literature search performed for the American College ofChest Physicians Evidence-Based Clinical Practice Guidelines?. ### Response: 2012.


Instruction: When were the American College ofChest Physicians Evidence-Based Clinical Practice Guidelines (9thEdition) published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were the American College ofChest Physicians Evidence-Based Clinical Practice Guidelines (9thEdition) published?. ### Response: 2012.


Instruction: What did the results of the systematic review inform?

Output: our recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the results of the systematic review inform?. ### Response: our recommendations.


Instruction: How did we search MEDLINE for literature regarding stroke risk inpatients with AF?

Output: via PubMed and theCochrane Library

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did we search MEDLINE for literature regarding stroke risk inpatients with AF?. ### Response: via PubMed and theCochrane Library.


Instruction: What search terms did we use to search for articles published from October 2009 to October 2017?

Output: “atrial ﬁbrillation, ”“atrialﬂutter, ”“risk assessment, ”“risk factors, ”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What search terms did we use to search for articles published from October 2009 to October 2017?. ### Response: “atrial ﬁbrillation, ”“atrialﬂutter, ”“risk assessment, ”“risk factors, ”.


Instruction: How did we search MEDLINE for literature regarding stroke and thromboembolism inpatients with AF?

Output: via PubMed and theCochrane Library

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did we search MEDLINE for literature regarding stroke and thromboembolism inpatients with AF?. ### Response: via PubMed and theCochrane Library.


Instruction: What term did we use to search for articles published from January 1, 2007 to October 2017?

Output: “coumarins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What term did we use to search for articles published from January 1, 2007 to October 2017?. ### Response: “coumarins.


Instruction: What is the name of the drug that is used to treat atrial fibrillation?

Output: antithrombotictherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat atrial fibrillation?. ### Response: antithrombotictherapy.


Instruction: What drug is used for catheter ablation?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used for catheter ablation?. ### Response: clopidogrel.


Instruction: How were the titles and abstracts of the search results reviewed?

Output: independentlyand in parallel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the titles and abstracts of the search results reviewed?. ### Response: independentlyand in parallel.


Instruction: What was done to identify potentially relevant articles based on the inclusion and exclusion criteria from the PICO elements?

Output: Titles and abstracts of the search results were reviewed independentlyand in parallel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was done to identify potentially relevant articles based on the inclusion and exclusion criteria from the PICO elements?. ### Response: Titles and abstracts of the search results were reviewed independentlyand in parallel.


Instruction: What was resolved by discussion?

Output: Discrepancies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was resolved by discussion?. ### Response: Discrepancies.


Instruction: Studies deemed eligiblewent a second round of what?

Output: full-text screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Studies deemed eligiblewent a second round of what?. ### Response: full-text screening.


Instruction: What tool was used to assess the risk of bias for randomized controlled trials?

Output: Risk of Bias Assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tool was used to assess the risk of bias for randomized controlled trials?. ### Response: Risk of Bias Assessment.


Instruction: What was extracted into structuredevidence tables?

Output: Important datafrom each included study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was extracted into structuredevidence tables?. ### Response: Important datafrom each included study.


Instruction: What is the International Carotid Stenting Study?

Output: an interim analysis of a randomised controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the International Carotid Stenting Study?. ### Response: an interim analysis of a randomised controlled trial.


Instruction: What does age modify the relative risk of?

Output: stenting versus endarterectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does age modify the relative risk of?. ### Response: stenting versus endarterectomy.


Instruction: What is the relative risk of stenting versus endarterectomy for symp-tomatic carotid stenosis?

Output: Short-term outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relative risk of stenting versus endarterectomy for symp-tomatic carotid stenosis?. ### Response: Short-term outcome.


Instruction: What was a pooled analysis of EV A-3S, SPACE and ICSS?

Output: Age modifies the relative risk of stenting versus endarterectomy for symp-tomatic carotid stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a pooled analysis of EV A-3S, SPACE and ICSS?. ### Response: Age modifies the relative risk of stenting versus endarterectomy for symp-tomatic carotid stenosis.


Instruction: What is the short-term outcome after stenting versus endarterectomy for symptomatic carotid stenosis?

Output: Age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the short-term outcome after stenting versus endarterectomy for symptomatic carotid stenosis?. ### Response: Age.


Instruction: What is a preplanned meta-analysis of individual patient data?

Output: Short-term outcome after stenting versus endarterectomy for symptomatic carotid stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a preplanned meta-analysis of individual patient data?. ### Response: Short-term outcome after stenting versus endarterectomy for symptomatic carotid stenosis.


Instruction: What is a subgroup analysis of the Carotid Revascularization Endarterectomy versus Stenting Trial?

Output: Influence of sex on outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a subgroup analysis of the Carotid Revascularization Endarterectomy versus Stenting Trial?. ### Response: Influence of sex on outcomes.


Instruction: When did the Lancet Neurol. 2011:10:530-537?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet Neurol. 2011:10:530-537?. ### Response: 2011.


Instruction: What year was the Carotid Revascularization Endarterectomy Versus Stenting Trial conducted?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the Carotid Revascularization Endarterectomy Versus Stenting Trial conducted?. ### Response: 2011.


Instruction: Revascularization Endarterectomy Versus Stenting Trial. Stroke. 2011;42:3484–3490. 434 What is the 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/SIR/SNIS/SVS guideline on the management of patients?

Output: Age and outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Revascularization Endarterectomy Versus Stenting Trial. Stroke. 2011;42:3484–3490. 434 What is the 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/SIR/SNIS/SVS guideline on the management of patients?. ### Response: Age and outcomes.


Instruction: What is the 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVS guideline on the management of patients with extra-cranial carotid and vertebral artery disease?

Output: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVS guideline on the management of patients with extra-cranial carotid and vertebral artery disease?. ### Response: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.


Instruction: What was the report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

Output: 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extra-cranial carotid and vertebral artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extra-cranial carotid and vertebral artery disease.


Instruction: What is the acronym for American Association of Neurological Surgeons?

Output: Congress of Neurological Surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for American Association of Neurological Surgeons?. ### Response: Congress of Neurological Surgeons.


Instruction: What is another name for American Society of Neuroradiology?

Output: American College of Radiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for American Society of Neuroradiology?. ### Response: American College of Radiology.


Instruction: What is the name of the randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease?

Output: CREST Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease?. ### Response: CREST Investigators.


Instruction: What are the names of the societies for Vascular Medicine and Society of Vascular Surgery?

Output: Society of Interventional Radiology, Society of NeuroInterventional Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the societies for Vascular Medicine and Society of Vascular Surgery?. ### Response: Society of Interventional Radiology, Society of NeuroInterventional Surgery.


Instruction: What is low-dose aspirin used for in the primary prevention of cardiovascular disease in women?

Output: A randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low-dose aspirin used for in the primary prevention of cardiovascular disease in women?. ### Response: A randomized trial.


Instruction: What is the N Engl J Med. 2005:352:1293–1304.

Output: A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2005:352:1293–1304.. ### Response: A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women.


Instruction: How many hours from onset COR LOE New, Revised, or Unchanged?

Output: 6 to 24 Hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours from onset COR LOE New, Revised, or Unchanged?. ### Response: 6 to 24 Hours.


Instruction: How long after last known normal do patients with AIS have LVO in the anterior circulation?

Output: 6 to 16 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after last known normal do patients with AIS have LVO in the anterior circulation?. ### Response: 6 to 16 hours.


Instruction: What is recommended in patients with AIS within 16 to 24 hours of last known normal who have LVO in the anterior circulation and meet other DAWN eligibility criteria?

Output: mechanical thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with AIS within 16 to 24 hours of last known normal who have LVO in the anterior circulation and meet other DAWN eligibility criteria?. ### Response: mechanical thrombectomy.


Instruction: What criteria did the DAWN trial use to select patients with large anterior circulation vessel occlusion for treatment with mechanical thrombectomy between 6 and 24 hours from last time?

Output: clinical-core mismatch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria did the DAWN trial use to select patients with large anterior circulation vessel occlusion for treatment with mechanical thrombectomy between 6 and 24 hours from last time?. ### Response: clinical-core mismatch.


Instruction: What is the clinical-core mismatch?

Output: a combination of NIHSS score and imaging findings on CTP or DW-MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical-core mismatch?. ### Response: a combination of NIHSS score and imaging findings on CTP or DW-MRI.


Instruction: How long after last known normal did mechanical thrombectomy last?

Output: 6 and 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after last known normal did mechanical thrombectomy last?. ### Response: 6 and 24 hours.


Instruction: What was the mRS score in the treatment group compared to the placebo group?

Output: 0–2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mRS score in the treatment group compared to the placebo group?. ### Response: 0–2.


Instruction: How much difference was there in the adjusted difference between the two groups?

Output: 33%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much difference was there in the adjusted difference between the two groups?. ### Response: 33%.


Instruction: What was the posterior probability of superiority?

Output: >0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the posterior probability of superiority?. ### Response: >0.


Instruction: How many strokes with witnessed onset were there in DAWN?

Output: 12%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes with witnessed onset were there in DAWN?. ### Response: 12%)..


Instruction: What did the DEFUSE 3 trial use to select patients with large anterior circulation occlusion?

Output: perfusion-core mismatch and maximum core size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the DEFUSE 3 trial use to select patients with large anterior circulation occlusion?. ### Response: perfusion-core mismatch and maximum core size.


Instruction: How many hours from last seen well for mechanical thrombectomy did the trial show a benefit in functional outcome at 90 days in the treated group?

Output: 6 to 16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours from last seen well for mechanical thrombectomy did the trial show a benefit in functional outcome at 90 days in the treated group?. ### Response: 6 to 16.


Instruction: What was the mRS score 0–2, 44.6% versus 16.7%?

Output: DEFUSE 3 trial used perfusion-core mismatch and maximum core size as imaging criteria to select patients with large anterior circulation occlusion 6 to 16 hours from last seen well for mechanical thrombectomy. This trial showed a benefit in functional outcome at 90 days in the treated group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mRS score 0–2, 44.6% versus 16.7%?. ### Response: DEFUSE 3 trial used perfusion-core mismatch and maximum core size as imaging criteria to select patients with large anterior circulation occlusion 6 to 16 hours from last seen well for mechanical thrombectomy. This trial showed a benefit in functional outcome at 90 days in the treated group.


Instruction: The benefit was independently demonstrated for which subgroup of patients who met DAWN eligibility criteria?

Output: treated group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The benefit was independently demonstrated for which subgroup of patients who met DAWN eligibility criteria?. ### Response: treated group.


Instruction: What are the only RCTs showing benefit of mechanical thrombectomy >6 hours from onset?

Output: DAWN and DEFUSE 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the only RCTs showing benefit of mechanical thrombectomy >6 hours from onset?. ### Response: DAWN and DEFUSE 3.


Instruction: What criteria should be strictly adhered to in clinical practice?

Output: DAWN or DEFUSE 3 eligibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria should be strictly adhered to in clinical practice?. ### Response: DAWN or DEFUSE 3 eligibility.


Instruction: Future RCTs may demonstrate that additional eligibility criteria can be used to select patients who benefit from what?

Output: mechanical thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Future RCTs may demonstrate that additional eligibility criteria can be used to select patients who benefit from what?. ### Response: mechanical thrombectomy.


Instruction: What should be strictly adhered to in clinical practice?

Output: DAWN or DEFUSE 3 eligibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be strictly adhered to in clinical practice?. ### Response: DAWN or DEFUSE 3 eligibility.


Instruction: What is indicated in preference to the Mechanical Embolus Removal in Cerebral Ischemia device?

Output: Use of stent retrievers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated in preference to the Mechanical Embolus Removal in Cerebral Ischemia device?. ### Response: Use of stent retrievers.


Instruction: What is the technical goal of the thrombectomy procedure?

Output: reperfusion to a modified Thrombolysis in Cerebral Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the technical goal of the thrombectomy procedure?. ### Response: reperfusion to a modified Thrombolysis in Cerebral Infarction.


Instruction: What is mTICI?

Output: modified Thrombolysis in Cerebral Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is mTICI?. ### Response: modified Thrombolysis in Cerebral Infarction.


Instruction: What year was ARecommendation reworded for clarity?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was ARecommendation reworded for clarity?. ### Response: 2015.


Instruction: What aims to achieve reperfusion, not simply recanalization?

Output: Mechanical thrombectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What aims to achieve reperfusion, not simply recanalization?. ### Response: Mechanical thrombectomy.


Instruction: The mTICI score is the current assessment tool of choice with proven value in what?

Output: predicting clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The mTICI score is the current assessment tool of choice with proven value in what?. ### Response: predicting clinical outcomes.


Instruction: What is the acronym for Dietary Approaches to Stop Hypertension?

Output: DASH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Dietary Approaches to Stop Hypertension?. ### Response: DASH.


Instruction: What does QCDR stand for?

Output: Qualified Clinical Data Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does QCDR stand for?. ### Response: Qualified Clinical Data Registry.


Instruction: Where can ahajournals.org be found?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can ahajournals.org be found?. ### Response: http://ahajournals.org.


Instruction: How many deaths per 1000 participants in the standard BP control arm were there?

Output: 53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths per 1000 participants in the standard BP control arm were there?. ### Response: 53.


Instruction: How many deathsper 1000 participants were there in the intensive BP controlled arm?

Output: 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deathsper 1000 participants were there in the intensive BP controlled arm?. ### Response: 40.


Instruction: What was the statistical signi ficant difference of 13 fewer per1000 participants?

Output: 23 fewer —1 fewer deaths per1000 participants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the statistical signi ficant difference of 13 fewer per1000 participants?. ### Response: 23 fewer —1 fewer deaths per1000 participants.


Instruction: How many deaths are there per 1000 participants?

Output: 53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths are there per 1000 participants?. ### Response: 53.


Instruction: What are the CKD subgroups in bothACCORD and SPRINT combined for?

Output: comprised all patients with diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the CKD subgroups in bothACCORD and SPRINT combined for?. ### Response: comprised all patients with diabetes.


Instruction: What are the 2018 Cholesterol Clinical Practice Guidelines?

Output: CLINICAL STATEMENTS  AND GUIDELINES S4.4.2-7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2018 Cholesterol Clinical Practice Guidelines?. ### Response: CLINICAL STATEMENTS  AND GUIDELINES S4.4.2-7.


Instruction: What is the DOI of the 2018 CIR.0000000000000625 June 18/25, 2019 e1131CLINICAL STATEMENTS AND GUIDELINES?

Output: 10.1161

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI of the 2018 CIR.0000000000000625 June 18/25, 2019 e1131CLINICAL STATEMENTS AND GUIDELINES?. ### Response: 10.1161.


Instruction: What year was the CD004816 released?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the CD004816 released?. ### Response: 2013.


Instruction: What year did the N Engl J Med issue 374:2021-31?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the N Engl J Med issue 374:2021-31?. ### Response: 2016.


Instruction: How did the association between lower LDL-C and cardiovascular risk reduction compare?

Output: different thera-peutic interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the association between lower LDL-C and cardiovascular risk reduction compare?. ### Response: different thera-peutic interventions.


Instruction: What is risk reduction among different thera-peutic interventions?

Output: cardiovascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is risk reduction among different thera-peutic interventions?. ### Response: cardiovascular.


Instruction: What is the JAMA 316:1289-97?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JAMA 316:1289-97?. ### Response: 2016.


Instruction: Karmali KN, Goff DC Jr, Ning H, and al. A systematic examination of the 2013 ACC/AHA pooled cohort risk assessment tool for athero-sclerotic cardiovascular disease.

Output: 64:959–68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Karmali KN, Goff DC Jr, Ning H, and al. A systematic examination of the 2013 ACC/AHA pooled cohort risk assessment tool for athero-sclerotic cardiovascular disease.. ### Response: 64:959–68.


Instruction: What is the name of the journal that validates atherosclerotic cardiovascular disease pooled cohort risk equations?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that validates atherosclerotic cardiovascular disease pooled cohort risk equations?. ### Response: JAMA.


Instruction: What is Krumholz HM's title?

Output: Treatment of cholesterol in 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Krumholz HM's title?. ### Response: Treatment of cholesterol in 2017.


Instruction: How is cholesterol treated in 2017?

Output: high-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is cholesterol treated in 2017?. ### Response: high-intensity statin therapy.


Instruction: What is the role of a clinician-patient in atherosclerotic cardiovascular disease prevention?

Output: risk discus-sion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of a clinician-patient in atherosclerotic cardiovascular disease prevention?. ### Response: risk discus-sion.


Instruction: What are the 2013 ACC/AHA guidelines?

Output: Clinician-patient risk discus-sion for atherosclerotic cardiovascular disease prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2013 ACC/AHA guidelines?. ### Response: Clinician-patient risk discus-sion for atherosclerotic cardiovascular disease prevention.


Instruction: When did the J Am Coll Cardiol. 2015 65:1361–8.

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol. 2015 65:1361–8.. ### Response: 2015.


Instruction: What is a decision aid for people facing?

Output: health treatment or screening decisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a decision aid for people facing?. ### Response: health treatment or screening decisions.


Instruction: What is the Cochrane Database Syst Rev. 2017:CD001431. S4.4.2-15. Mortensen MB, Fuster V, Muntendam P, et al. A simple disease-guided approach to personalize statin allocation in elderly people: the BioImage study.

Output: Decision aids for people facing health treatment or screening decisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Cochrane Database Syst Rev. 2017:CD001431. S4.4.2-15. Mortensen MB, Fuster V, Muntendam P, et al. A simple disease-guided approach to personalize statin allocation in elderly people: the BioImage study.. ### Response: Decision aids for people facing health treatment or screening decisions.


Instruction: How long did the Bruneck study last?

Output: 15-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Bruneck study last?. ### Response: 15-year.


Instruction: What is the name of the study in which lipoprotein(a) was used to discriminate and reclassify cardiovascular risk?

Output: Bruneck study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study in which lipoprotein(a) was used to discriminate and reclassify cardiovascular risk?. ### Response: Bruneck study.


Instruction: What does MESA stand for?

Output: Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MESA stand for?. ### Response: Multi-Ethnic Study of Atherosclerosis.


Instruction: What is the name of the group that studies the effects of coro-nary artery calcium testing?

Output: MESA (Multi-Ethnic Study of Atherosclerosis)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies the effects of coro-nary artery calcium testing?. ### Response: MESA (Multi-Ethnic Study of Atherosclerosis).


Instruction: What is the potential impact of high-intensity statin therapy on LDL cholesterol?

Output: Percent reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the potential impact of high-intensity statin therapy on LDL cholesterol?. ### Response: Percent reduction.


Instruction: What are potential implications for guidelines and for the prescription of emerging lipid-lowering agents?

Output: Percent reduction in LDL cholesterol following high-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are potential implications for guidelines and for the prescription of emerging lipid-lowering agents?. ### Response: Percent reduction in LDL cholesterol following high-intensity statin therapy.


Instruction: When did Eur Heart J. 2016;37:1373–9. What was the association between age and coronary artery calcium score?

Output: cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 2016;37:1373–9. What was the association between age and coronary artery calcium score?. ### Response: cardiovascular risk.


Instruction: What is the name of the study that analyzed pooled population-based studies?

Output: JAMA Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that analyzed pooled population-based studies?. ### Response: JAMA Cardiol.


Instruction: What was the JAMA Cardiol. 2017;2:986-94?

Output: Association of coronary artery calcium score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the JAMA Cardiol. 2017;2:986-94?. ### Response: Association of coronary artery calcium score.


Instruction: What is the evidence gap regarding the use of anticoagulation during CPB?

Output: 105:650 –62

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the evidence gap regarding the use of anticoagulation during CPB?. ### Response: 105:650 –62.


Instruction: What does this article review relevant information about?

Output: the use of anticoagulationfor the conduct of CPB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does this article review relevant information about?. ### Response: the use of anticoagulationfor the conduct of CPB.


Instruction: What is the only comprehensive guideline of its kind?

Output: anticoagulationtreatment during CPB. This article reviews relevantpublished information about the use of anticoagulationfor the conduct of CPB and provides a synthesis of theavailable evidence to create a clinical practice guideline.This guideline represents the initial evidence-basedapproach to the use of anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only comprehensive guideline of its kind?. ### Response: anticoagulationtreatment during CPB. This article reviews relevantpublished information about the use of anticoagulationfor the conduct of CPB and provides a synthesis of theavailable evidence to create a clinical practice guideline.This guideline represents the initial evidence-basedapproach to the use of anticoagulation.


Instruction: What did the authors hope the guideline would stim-ulate investigators to do?

Output: amplify and elaborate on the evi-dence available on this topic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the authors hope the guideline would stim-ulate investigators to do?. ### Response: amplify and elaborate on the evi-dence available on this topic.


Instruction: What did the systematic review outline to identify relevant evidence?

Output: literature searches

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the systematic review outline to identify relevant evidence?. ### Response: literature searches.


Instruction: What was used to conduct literature searches inPubMed using standardized medical subject heading(MeSH) terms from the National Library of Medicine?

Output: listof search terms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to conduct literature searches inPubMed using standardized medical subject heading(MeSH) terms from the National Library of Medicine?. ### Response: listof search terms.


Instruction: What is the MeSH number for extracorporeal membrane oxygenation?

Output: E04.292

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MeSH number for extracorporeal membrane oxygenation?. ### Response: E04.292.


Instruction: What are the terms for Cardiovascular surgical procedures?

Output: C15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the terms for Cardiovascular surgical procedures?. ### Response: C15.


Instruction: What is the MeSH number for anticoagulant drugs?

Output: D27.505

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MeSH number for anticoagulant drugs?. ### Response: D27.505.


Instruction: What are some of the broad search terms that allowed specific topics to beadded?

Output: Abbreviations and Acronyms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the broad search terms that allowed specific topics to beadded?. ### Response: Abbreviations and Acronyms.


Instruction: What did the broad search terms allow specific topics to beadded to the search with?

Output: logical “AND ”connector

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the broad search terms allow specific topics to beadded to the search with?. ### Response: logical “AND ”connector.


Instruction: What is ACT = activated clotting time?

Output: connector andAbbreviations and Acronyms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACT = activated clotting time?. ### Response: connector andAbbreviations and Acronyms.


Instruction: What is heparin-induced platelet activation?

Output: HIPA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heparin-induced platelet activation?. ### Response: HIPA.


Instruction: What is the medical subject headingPF4 = platelet factor 4RCT = randomized controlled trial?

Output: MeSH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the medical subject headingPF4 = platelet factor 4RCT = randomized controlled trial?. ### Response: MeSH.


Instruction: How many patients with arterial hypertension were treated with Trandolapril Cardiac Event?

Output: 1407

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with arterial hypertension were treated with Trandolapril Cardiac Event?. ### Response: 1407.


Instruction: What was the name of the TRACE Study Group?

Output: Trandolapril Cardiac Event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the TRACE Study Group?. ### Response: Trandolapril Cardiac Event.


Instruction: What is lisin-opril angiotensin-converting enzyme inhibitor used for?

Output: chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lisin-opril angiotensin-converting enzyme inhibitor used for?. ### Response: chronic heart failure.


Instruction: What is the name of the study group that investigated the effects of low and high doses of the angiostensin converting enzyme on heart failure?

Output: Atlas Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that investigated the effects of low and high doses of the angiostensin converting enzyme on heart failure?. ### Response: Atlas Study Group.


Instruction: What is the name of the study that investigated the effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy?

Output: RENAAL Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy?. ### Response: RENAAL Study Investigators.


Instruction: What was the N Engl J Med. 2001 345:861-869?

Output: Effects of losartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med. 2001 345:861-869?. ### Response: Effects of losartan.


Instruction: What was the impact of achieved blood pressure on cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial?

Output: Impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the impact of achieved blood pressure on cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial?. ### Response: Impact.


Instruction: What was the outcome of the Irbesartan Diabetic Nephropathy Trial?

Output: achieved blood pressure on cardiovascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the Irbesartan Diabetic Nephropathy Trial?. ### Response: achieved blood pressure on cardiovascular outcomes.


Instruction: What is the effect of losartan compared with captopril on mortality in patients with symptomatic nephropathy?

Output: renal and cardiovascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of losartan compared with captopril on mortality in patients with symptomatic nephropathy?. ### Response: renal and cardiovascular outcomes.


Instruction: Losartan compared to captopril on mortality in patients with symptomatic heart failure?

Output: candesartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Losartan compared to captopril on mortality in patients with symptomatic heart failure?. ### Response: candesartan.


Instruction: What is the name of the randomised trial?

Output: Losartan Heart Failure Survival Study ELITE II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial?. ### Response: Losartan Heart Failure Survival Study ELITE II.


Instruction: What is valsartan used for in chronic heart failure?

Output: angiotensin-receptor blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is valsartan used for in chronic heart failure?. ### Response: angiotensin-receptor blocker.


Instruction: When did N Engl J Med issue 345:1667-1675?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 345:1667-1675?. ### Response: 2001.


Instruction: What is the effect of candesartan in patients with heart failure and reduced left-ventricular systolic function intolerant to?

Output: angiotensin-converting-enzyme inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of candesartan in patients with heart failure and reduced left-ventricular systolic function intolerant to?. ### Response: angiotensin-converting-enzyme inhibitors.