Instruction: What is a Class IIb recommendation?

Output: with orwithout involvement of the proximal [left anteriordescending] artery) or 1-vessel proximal [left anteriordescending] disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Class IIb recommendation?. ### Response: with orwithout involvement of the proximal [left anteriordescending] artery) or 1-vessel proximal [left anteriordescending] disease.


Instruction: What is the AUC rated by experts?

Output: uncertain to appropriate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AUC rated by experts?. ### Response: uncertain to appropriate.


Instruction: What are becoming a frequent part of daily clinicalpractice and of quality-improvement efforts?

Output: the criteriafor the AUC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are becoming a frequent part of daily clinicalpractice and of quality-improvement efforts?. ### Response: the criteriafor the AUC.


Instruction: What did we create that more broadly captured appropriate use of PCI?

Output: ameasure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we create that more broadly captured appropriate use of PCI?. ### Response: ameasure.


Instruction: What did the writing committee consider that the current measure does not entirely meet?

Output: the strict criteria for accountability measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing committee consider that the current measure does not entirely meet?. ### Response: the strict criteria for accountability measures.


Instruction: Who put forth the strict criteria for accountability measures?

Output: Chassin et al. (27) and the ACC/AHA Task Force onPerformance Measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who put forth the strict criteria for accountability measures?. ### Response: Chassin et al. (27) and the ACC/AHA Task Force onPerformance Measures.


Instruction: What is consistent with the measure-ment of appropriateness of PCI?

Output: uncertain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is consistent with the measure-ment of appropriateness of PCI?. ### Response: uncertain.


Instruction: What was the cause of one patient's ischemic foot?

Output: intraaortic balloon pump

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the cause of one patient's ischemic foot?. ### Response: intraaortic balloon pump.


Instruction: How many patients died during the postoperative period?

Output: Three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients died during the postoperative period?. ### Response: Three.


Instruction: What is the range of 3 months to 1 year?

Output: postoperative period

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the range of 3 months to 1 year?. ### Response: postoperative period.


Instruction: What is loprost?

Output: prostacyclin analogue

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is loprost?. ### Response: prostacyclin analogue.


Instruction: What was used to inhibit platelet activation dur-ing cardiac surgery?

Output: Iloprost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to inhibit platelet activation dur-ing cardiac surgery?. ### Response: Iloprost.


Instruction: How many consecutive cardiac surgery patients were analysed?

Output: 1,518

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many consecutive cardiac surgery patients were analysed?. ### Response: 1,518.


Instruction: How many consecutive cardiac surgery patients did Palatianos analyze?

Output: 1,518

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many consecutive cardiac surgery patients did Palatianos analyze?. ### Response: 1,518.


Instruction: How many patients with clinicalsymptoms of HIT were identified with PF4-heparin antibodies?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with clinicalsymptoms of HIT were identified with PF4-heparin antibodies?. ### Response: 10.


Instruction: What did patients presenting with HIT receive?

Output: a protocol ofiloprost infusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients presenting with HIT receive?. ### Response: a protocol ofiloprost infusion.


Instruction: What drug was used in conjunction with heparin?

Output: tiro ﬁban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was used in conjunction with heparin?. ### Response: tiro ﬁban.


Instruction: What was the postoperative reduction in platelet count in the iloprost group compared to the control group?

Output: 12.5% /C68.7%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the postoperative reduction in platelet count in the iloprost group compared to the control group?. ### Response: 12.5% /C68.7%).


Instruction: No thrombotic complications were detected in which group of patients?

Output: iloprost group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No thrombotic complications were detected in which group of patients?. ### Response: iloprost group.


Instruction: What was used in conjunction with a tiro fiban infusion during CPB?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used in conjunction with a tiro fiban infusion during CPB?. ### Response: heparin.


Instruction: There was no clinical or laboratory evidence of what?

Output: thrombosis or excessive bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There was no clinical or laboratory evidence of what?. ### Response: thrombosis or excessive bleeding.


Instruction: What has been reported with patientsrequiring renal replacement therapy?

Output: The use of argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been reported with patientsrequiring renal replacement therapy?. ### Response: The use of argatroban.


Instruction: What should be limited to theseexceptional circumstances?

Output: argatroban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be limited to theseexceptional circumstances?. ### Response: argatroban.


Instruction: What is the norm?

Output: excessive bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the norm?. ### Response: excessive bleeding.


Instruction: Patients who are seropositive for heparin antibodies are at increased risk of both thrombosis and bleeding?

Output: asso-ciated with heparin alternatives

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients who are seropositive for heparin antibodies are at increased risk of both thrombosis and bleeding?. ### Response: asso-ciated with heparin alternatives.


Instruction: What is a thrombotic complication associated with rapid-onset HIT in patients with a recent history of HIT?

Output: catastrophic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a thrombotic complication associated with rapid-onset HIT in patients with a recent history of HIT?. ### Response: catastrophic.


Instruction: Avery high level of vigilance is recommended in patients exposed to what?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Avery high level of vigilance is recommended in patients exposed to what?. ### Response: heparin.


Instruction: Patients warrant carefulsurveillance,thromboprophylaxis, and what else to manage the increased risk?

Output: treatments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients warrant carefulsurveillance,thromboprophylaxis, and what else to manage the increased risk?. ### Response: treatments.


Instruction: What is the most commonly used anticoagu-lant during the CardiacOperationsClass IIa Recommendation/C15Protamine dosing for heparin reversal?

Output: Heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most commonly used anticoagu-lant during the CardiacOperationsClass IIa Recommendation/C15Protamine dosing for heparin reversal?. ### Response: Heparin.


Instruction: What has been associated with reducedbleeding and blood transfusion?

Output: Protamine dosing for heparin reversal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been associated with reducedbleeding and blood transfusion?. ### Response: Protamine dosing for heparin reversal.


Instruction: What is the most commonly used anticoagu-lant during the conduct of cardiac operations?

Output: Heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most commonly used anticoagu-lant during the conduct of cardiac operations?. ### Response: Heparin.


Instruction: What are the goals of successful anticoagulation during CPB?

Output: limiting clotting and safely reversing theanticoagulation effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the goals of successful anticoagulation during CPB?. ### Response: limiting clotting and safely reversing theanticoagulation effect.


Instruction: Who is the EDITOR of ParisClinical Investigation?

Output: Pierre Ronco

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the EDITOR of ParisClinical Investigation?. ### Response: Pierre Ronco.


Instruction: What is the name of the PAST EDITORS in Columbus?

Output: Brad Rovin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PAST EDITORS in Columbus?. ### Response: Brad Rovin.


Instruction: Where is the New YorkSaulo Klahr based?

Output: St. Louis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the New YorkSaulo Klahr based?. ### Response: St. Louis.


Instruction: LondonRajasekhar Ramakrishnan, New YorkKI FELLOWSHIP INTERNSAnna Francis, BrisbaneSethu Madhavan, ColumbusASSOCIATE EDITORSP. Toby Coates, AdelaideTransplant and ImmunologyOlivier Devuyst, ZurichPhysiology, Genetics, Kidney CancerTilman B. Drueke, ParisCKD, Hypertension, Nephrolithiasis, CKD-MBDAgnes B. Fogo, NashvilleClinical and Experimental Renal PathologyT.

Output: itsch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LondonRajasekhar Ramakrishnan, New YorkKI FELLOWSHIP INTERNSAnna Francis, BrisbaneSethu Madhavan, ColumbusASSOCIATE EDITORSP. Toby Coates, AdelaideTransplant and ImmunologyOlivier Devuyst, ZurichPhysiology, Genetics, Kidney CancerTilman B. Drueke, ParisCKD, Hypertension, Nephrolithiasis, CKD-MBDAgnes B. Fogo, NashvilleClinical and Experimental Renal PathologyT.. ### Response: itsch.


Instruction: Who is the editor of KIR?

Output: Jai Radhakrishnan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the editor of KIR?. ### Response: Jai Radhakrishnan.


Instruction: What is the name of the editor who specializes in Clinical Studies and Images in Nephrology?

Output: KIR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the editor who specializes in Clinical Studies and Images in Nephrology?. ### Response: KIR.


Instruction: In what city is Anupam Agarwal located?

Output: Birmingham

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what city is Anupam Agarwal located?. ### Response: Birmingham.


Instruction: What city is Basile located in?

Output: Indianapolis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What city is Basile located in?. ### Response: Indianapolis.


Instruction: Where is Peter Boor located?

Output: Aachen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Peter Boor located?. ### Response: Aachen.


Instruction: Who is based in Bangkok?

Output: Somchai Eiam-Ong

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is based in Bangkok?. ### Response: Somchai Eiam-Ong.


Instruction: Which city is Fernette D’Agati based?

Output: New York

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which city is Fernette D’Agati based?. ### Response: New York.


Instruction: What is the name of the city in which Doi lives?

Output: Tokyo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the city in which Doi lives?. ### Response: Tokyo.


Instruction: What city in the United States is home to Doi?

Output: Toronto

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What city in the United States is home to Doi?. ### Response: Toronto.


Instruction: Where is the city of Dallas located?

Output: Bangkok

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the city of Dallas located?. ### Response: Bangkok.


Instruction: What is the name of the person who lives in Laguna Niguel?

Output: Richard Glassock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who lives in Laguna Niguel?. ### Response: Richard Glassock.


Instruction: Where is Mark Haas based?

Output: Los Angeles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Mark Haas based?. ### Response: Los Angeles.


Instruction: What city is John C. Harris based in?

Output: Rochester

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What city is John C. Harris based in?. ### Response: Rochester.


Instruction: Who lives in Chicago?

Output: John Daugirdas

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who lives in Chicago?. ### Response: John Daugirdas.


Instruction: What city is Frederick Kaskel located in?

Output: New York

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What city is Frederick Kaskel located in?. ### Response: New York.


Instruction: What is the name of the city where Frederic Kaskel is located?

Output: New York

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the city where Frederic Kaskel is located?. ### Response: New York.


Instruction: Who is the city of Ann Arbor?

Output: Matthias Kretzler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the city of Ann Arbor?. ### Response: Matthias Kretzler.


Instruction: What is not recommended within 21 d of a GI bleeding event?

Output: Alteplase administration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended within 21 d of a GI bleeding event?. ### Response: Alteplase administration.


Instruction: Where can Alteplase be downloaded from?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can Alteplase be downloaded from?. ### Response: http://ahajournals.org.


Instruction: Where can you find mor e information and committ ee details?

Output: Updat e information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find mor e information and committ ee details?. ### Response: Updat e information.


Instruction: When was the last updat ed?

Output: 17 April 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed?. ### Response: 17 April 2023.


Instruction: What is the name of the book NG133?

Output: Hyper tension in pr egnancy: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book NG133?. ### Response: Hyper tension in pr egnancy: diagnosis and management.


Instruction: What was the last updat ed 17 April 2023?

Output: Page 4of 59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the last updat ed 17 April 2023?. ### Response: Page 4of 59.


Instruction: How many pages of 59 were on this page?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages of 59 were on this page?. ### Response: 4.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett.


Instruction: What is the name of the guideline published by ACC and AHA?

Output: Guideline on the Primary Prevention of Cardiovascular Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline published by ACC and AHA?. ### Response: Guideline on the Primary Prevention of Cardiovascular Disease.


Instruction: When was the Mayo Clin Proc. 2016?

Output: 91:343–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Mayo Clin Proc. 2016?. ### Response: 91:343–.


Instruction: What are older adults with coronary artery disease?

Output: Normal-weight central obesity and mortality risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are older adults with coronary artery disease?. ### Response: Normal-weight central obesity and mortality risk.


Instruction: What are the Mayo Clin Proc. 2016:343–51?

Output: Normal-weight central obesity and mortality risk in older adults with coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Mayo Clin Proc. 2016:343–51?. ### Response: Normal-weight central obesity and mortality risk in older adults with coronary artery disease.


Instruction: Garvey WT, Mechanick JI, Brett EM, et al. Comprehensive clinical practice guidelines for medical care of patients with obesity.

Output: 2016;22 suppl 3:1–203

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Garvey WT, Mechanick JI, Brett EM, et al. Comprehensive clinical practice guidelines for medical care of patients with obesity.. ### Response: 2016;22 suppl 3:1–203.


Instruction: Endocr Pract. 2016;22suppl 3:1–203.

Output: suppl

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Endocr Pract. 2016;22suppl 3:1–203.. ### Response: suppl.


Instruction: What is the acronym for International Day for the Evaluation of Abdominal Obesity?

Output: IDEA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for International Day for the Evaluation of Abdominal Obesity?. ### Response: IDEA.


Instruction: How many primary care patients in 63 countries were studied for IDEA?

Output: 168 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many primary care patients in 63 countries were studied for IDEA?. ### Response: 168 000.


Instruction: When was Circulation 116: 1942-51?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation 116: 1942-51?. ### Response: 2007.


Instruction: How many countries are in the Obesity Education Initiative?

Output: 63

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many countries are in the Obesity Education Initiative?. ### Response: 63.


Instruction: Where is the National Heart, Lung, and Blood Institute located?

Output: Bethesda, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the National Heart, Lung, and Blood Institute located?. ### Response: Bethesda, MD.


Instruction: When was the Circulation. 2007:116: 1942-51?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation. 2007:116: 1942-51?. ### Response: 2007.


Instruction: What year was the National Heart, Lung and Blood Institute founded?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the National Heart, Lung and Blood Institute founded?. ### Response: 1998.


Instruction: What is the name of the book available at the ncbi?

Output: NBK2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book available at the ncbi?. ### Response: NBK2003.


Instruction: When was the book released?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the book released?. ### Response: 1998.


Instruction: Where can you find the book?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the book?. ### Response: https://www.ncbi.nlm.nih.gov/books/NBK2003/..


Instruction: What does DASH stand for?

Output: Dietary Approaches to Stop Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does DASH stand for?. ### Response: Dietary Approaches to Stop Hypertension.


Instruction: What is the name of the randomized crossover clinical trial of DASH?

Output: Dietary Approaches to Stop Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized crossover clinical trial of DASH?. ### Response: Dietary Approaches to Stop Hypertension.


Instruction: What is the name of the randomized crossover clinical trial?

Output: Dietary Approaches to Stop Hypertension (DASH) eating plan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized crossover clinical trial?. ### Response: Dietary Approaches to Stop Hypertension (DASH) eating plan.


Instruction: What type of diabetic patients are influenced by different modes of exercise training?

Output: type 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetic patients are influenced by different modes of exercise training?. ### Response: type 2.


Instruction: How does exercise training affect glucose control?

Output: Effects of different modes of exercise training on glucose control and risk factors for complications in type 2 diabetic patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does exercise training affect glucose control?. ### Response: Effects of different modes of exercise training on glucose control and risk factors for complications in type 2 diabetic patients.


Instruction: What is the name of the randomized controlled trial in which aerobic and resis-tance training have been shown to have an effect on hemoglobin A1c levels in patients with type 2 diabetes?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial in which aerobic and resis-tance training have been shown to have an effect on hemoglobin A1c levels in patients with type 2 diabetes?. ### Response: JAMA.


Instruction: When was the JAMA 304:2253-62 published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA 304:2253-62 published?. ### Response: 2010.


Instruction: What did the UKPDS 34 show about the effects of intensive blood-glucose control?

Output: Effect of intensive blood-glucose control with metformin on com-plications in overweight patients with type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the UKPDS 34 show about the effects of intensive blood-glucose control?. ### Response: Effect of intensive blood-glucose control with metformin on com-plications in overweight patients with type 2 diabetes.


Instruction: How many overweight patients have type 2 diabetes?

Output: 34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many overweight patients have type 2 diabetes?. ### Response: 34.


Instruction: What is the name of the UKPDS group?

Output: UK Prospective Diabetes Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the UKPDS group?. ### Response: UK Prospective Diabetes Study.


Instruction: When did the UK Prospective Diabetes Study Group publish?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the UK Prospective Diabetes Study Group publish?. ### Response: 1998.


Instruction: How many people had type 2 diabetics in 1998?

Output: 352:854–65

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people had type 2 diabetics in 1998?. ### Response: 352:854–65.


Instruction: What is the name of the review and meta-analysis?

Output: Diabetes medications as monotherapy or metformin-based combination therapy for type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the review and meta-analysis?. ### Response: Diabetes medications as monotherapy or metformin-based combination therapy for type 2 diabetes.


Instruction: What are the names of the authors of the study?

Output: Azadbakht L, Fard NRP , Karimi M, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the study?. ### Response: Azadbakht L, Fard NRP , Karimi M, et al.


Instruction: How does the study compare the effects of metformin and glipizide?

Output: cardiovascular outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the study compare the effects of metformin and glipizide?. ### Response: cardiovascular outcomes.


Instruction: What does FDA approve?

Output: the new NCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does FDA approve?. ### Response: the new NCD.


Instruction: What is the new NCD?

Output: FDA approval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the new NCD?. ### Response: FDA approval.


Instruction: When will J Am Coll Car-diol be published?

Output: 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will J Am Coll Car-diol be published?. ### Response: 2020.


Instruction: What is the name of the study that compares mechanical prostheses to peri-cardial tissue valves?

Output: Veterans Affairs randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares mechanical prostheses to peri-cardial tissue valves?. ### Response: Veterans Affairs randomized trial.


Instruction: What year did the J Thorac Cardiovasc Surg issue 144:1075–83?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the J Thorac Cardiovasc Surg issue 144:1075–83?. ### Response: 2012.


Instruction: How long after valve replacement do patients with aortic valve replacement experience the same outcome?

Output: 15 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after valve replacement do patients with aortic valve replacement experience the same outcome?. ### Response: 15 years.


Instruction: How many years after valve replacement did the Veterans Affairs randomized trial show?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years after valve replacement did the Veterans Affairs randomized trial show?. ### Response: 15.


Instruction: What was the outcome of the VA randomized study?

Output: Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the VA randomized study?. ### Response: Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve.


Instruction: When was the J Am Coll Cardiol 36:1152–8?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 36:1152–8?. ### Response: 2000.


Instruction: How long after aortic valve replacement did composites of valve related complications assess performance of bioprostheses and mechanical prostheses?

Output: 15 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after aortic valve replacement did composites of valve related complications assess performance of bioprostheses and mechanical prostheses?. ### Response: 15 years.


Instruction: What is the name of the study that evaluated the performance of mechanical prosthesis to 15 years?

Output: Veterans Affairs randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the performance of mechanical prosthesis to 15 years?. ### Response: Veterans Affairs randomized trial.


Instruction: When was the J Thorac Cardiovasc Surg. 2006;131:1267–73?

Output: 15 years after aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg. 2006;131:1267–73?. ### Response: 15 years after aortic valve replacement.


Instruction: How many patients were analyzed over 5 years by the Society for Cardiothoracic Surgery in Great Britain and Ireland?

Output: 41,227

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were analyzed over 5 years by the Society for Cardiothoracic Surgery in Great Britain and Ireland?. ### Response: 41,227.


Instruction: What is the name of the database that analyzed 41,227 patients?

Output: Society for Cardiothoracic Sur -gery in Great Britain and Ireland National database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the database that analyzed 41,227 patients?. ### Response: Society for Cardiothoracic Sur -gery in Great Britain and Ireland National database.


Instruction: What is the age range for aortic valve replacement?

Output: 55 to 70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age range for aortic valve replacement?. ### Response: 55 to 70 years.


Instruction: What are the ages for mechanical versus biological valves?

Output: 55 to 70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the ages for mechanical versus biological valves?. ### Response: 55 to 70 years.


Instruction: When was the J Am Coll Cardiol.54:1862–8?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol.54:1862–8?. ### Response: 2009.


Instruction: How long did the Carpentier-Edwards aortic pericardial bioprosthesis last?

Output: 17 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Carpentier-Edwards aortic pericardial bioprosthesis last?. ### Response: 17 years.


Instruction: What is the name of the database used to compare mechanical versus biologic prostheses in older patients?

Output: Society of Thoracic Surgeons Adult Cardiac Surgery National Database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the database used to compare mechanical versus biologic prostheses in older patients?. ### Response: Society of Thoracic Surgeons Adult Cardiac Surgery National Database.


Instruction: When did Circulation 2013 issue 127:1647-55?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation 2013 issue 127:1647-55?. ### Response: 2013.


Instruction: What is the Carpentier-Edwards aortic pericardial bioprosthesis?

Output: Perimount

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Carpentier-Edwards aortic pericardial bioprosthesis?. ### Response: Perimount.


Instruction: What are the clinical out-comes of late hemodynamic and clinical outcomes?

Output: 29

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinical out-comes of late hemodynamic and clinical outcomes?. ### Response: 29.


Instruction: How many patients have had the Biocor porcine bioprosthesis for 20 years?

Output: 1712

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients have had the Biocor porcine bioprosthesis for 20 years?. ### Response: 1712.


Instruction: What is the name of the patient who had the Han-cock II prosthesis?

Output: Bech-Hansen O

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the patient who had the Han-cock II prosthesis?. ### Response: Bech-Hansen O.


Instruction: What is the Ross procedure in adults for car -diologists and cardiac Surgeons: JACC state-of-the-art review?

Output: Mazine A, El-Hamamsy I, Verma S, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Ross procedure in adults for car -diologists and cardiac Surgeons: JACC state-of-the-art review?. ### Response: Mazine A, El-Hamamsy I, Verma S, et al.


Instruction: What does SAVR Versus TAVI do for Patients for Whom a Bioprosthetic AVR Is Appropriate?

Output: Choice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SAVR Versus TAVI do for Patients for Whom a Bioprosthetic AVR Is Appropriate?. ### Response: Choice.


Instruction: What type of valve replacement is recommended in patients with severe aortic stenosis?

Output: Transcatheter versus surgi-cal aortic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve replacement is recommended in patients with severe aortic stenosis?. ### Response: Transcatheter versus surgi-cal aortic.


Instruction: What is the difference between a transcatheter and surgi-cal valve replacement?

Output: severe aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between a transcatheter and surgi-cal valve replacement?. ### Response: severe aortic stenosis.


Instruction: How much of the telmisartan group had cardiovascular death, nonfatal MI, and stroke?

Output: 15.7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the telmisartan group had cardiovascular death, nonfatal MI, and stroke?. ### Response: 15.7%.


Instruction: What percentage of the placebo group had HF?

Output: 17.0%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the placebo group had HF?. ### Response: 17.0%.


Instruction: Which group of patients had a composite of cardio-death, MI, stroke, and hospitalization?

Output: telmisartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which group of patients had a composite of cardio-death, MI, stroke, and hospitalization?. ### Response: telmisartan.


Instruction: What percentage of patients in the telmisartan group had a cardiovascular hospitalization?

Output: 30.3%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in the telmisartan group had a cardiovascular hospitalization?. ### Response: 30.3%.


Instruction: What was the tolerability of telmesartan compared to that of placebo?

Output: similar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the tolerability of telmesartan compared to that of placebo?. ### Response: similar.


Instruction: What was well tolerated on the composite outcome end point of cardiovascular death, MI, and stroke?

Output: telmisartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was well tolerated on the composite outcome end point of cardiovascular death, MI, and stroke?. ### Response: telmisartan.


Instruction: What does spironolactone and eplerenone lower when added to other antihypertensive agents?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does spironolactone and eplerenone lower when added to other antihypertensive agents?. ### Response: BP.


Instruction: What is the name of the study?

Output: Randomized Aldactone Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: Randomized Aldactone Evaluation.


Instruction: When was the Randomized Aldactone Evaluation Downloaded?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Randomized Aldactone Evaluation Downloaded?. ### Response: May 3, 2023.


Instruction: What is a reasonable cutoff value based on the available literature?

Output: an esti-mated CrCl of about 30 mL/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable cutoff value based on the available literature?. ### Response: an esti-mated CrCl of about 30 mL/min.


Instruction: What is an esti-mated CrCl of about 30 mL/min?

Output: /H11350

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an esti-mated CrCl of about 30 mL/min?. ### Response: /H11350.


Instruction: Anti-Xa monitoring LMWH in doses adjusted by what?

Output: total body weight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anti-Xa monitoring LMWH in doses adjusted by what?. ### Response: total body weight.


Instruction: What is a strong negative correlation between total body weight and anti Xa levels in obese patients?

Output: thromboprophylaxis with ﬁ  xed-dose enoxaparin and nadroparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strong negative correlation between total body weight and anti Xa levels in obese patients?. ### Response: thromboprophylaxis with ﬁ  xed-dose enoxaparin and nadroparin.


Instruction: How many small prospective trials have examined LMWH in patients undergoing bariatric surgery?

Output: Several

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many small prospective trials have examined LMWH in patients undergoing bariatric surgery?. ### Response: Several.


Instruction: What is uncertain in patients with severe renal insuffi ciency?

Output: Appropriate dosing of LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is uncertain in patients with severe renal insuffi ciency?. ### Response: Appropriate dosing of LMWH.


Instruction: How many pharmacokinetic studies have shown that LMWH is safe?

Output: 153

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pharmacokinetic studies have shown that LMWH is safe?. ### Response: 153.


Instruction: What has excluded patients with severe renal insufficiency?

Output: Contempo-rary randomized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has excluded patients with severe renal insufficiency?. ### Response: Contempo-rary randomized controlled trials.


Instruction: 153 pharmacokinetic studies have demonstrated that clearance of the anti-Xa effect of LMWH is highly correlated with what?

Output: CrCl

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 153 pharmacokinetic studies have demonstrated that clearance of the anti-Xa effect of LMWH is highly correlated with what?. ### Response: CrCl.


Instruction: What was observed in a large study of patients receiv ing therapeutic-dose enoxaparin for coronary indications?

Output: a strong linear relationship was reported between CrCl and enoxaparin clearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was observed in a large study of patients receiv ing therapeutic-dose enoxaparin for coronary indications?. ### Response: a strong linear relationship was reported between CrCl and enoxaparin clearance.


Instruction: What was a strong linear relationship reported between CrCl and enoxaparin clearance?

Output: R   5  0.85,  P   ,  .001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a strong linear relationship reported between CrCl and enoxaparin clearance?. ### Response: R   5  0.85,  P   ,  .001.


Instruction: What is of concern after multiple therapeutic doses?

Output: accumulation of anti-Xa activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is of concern after multiple therapeutic doses?. ### Response: accumulation of anti-Xa activity.


Instruction: What was shown to increase anti-Xa levels after multiple therapeutic doses of enoxaparin?

Output: CrCl

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was shown to increase anti-Xa levels after multiple therapeutic doses of enoxaparin?. ### Response: CrCl.


Instruction: What did sig-nifi cantly increase in patients with a CrCl, 30 mL/min?

Output: anti-Xa levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did sig-nifi cantly increase in patients with a CrCl, 30 mL/min?. ### Response: anti-Xa levels.


Instruction: What is CrCl?

Output: creatinine clearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CrCl?. ### Response: creatinine clearance.


Instruction: Accumulation after multiple prophylactic doses appears less frequently, but it is still observed?

Output: 155

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Accumulation after multiple prophylactic doses appears less frequently, but it is still observed?. ### Response: 155.


Instruction: Anti-Xa clearance was reduced by 39% after what?

Output: multiple prophy-lactic doses of enoxaparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anti-Xa clearance was reduced by 39% after what?. ### Response: multiple prophy-lactic doses of enoxaparin.


Instruction: How much higher was drug exposure in CrCl patients?

Output: 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was drug exposure in CrCl patients?. ### Response: 35%.


Instruction: What was the percentage of higher drug exposure?

Output: 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the percentage of higher drug exposure?. ### Response: 35%.


Instruction: What is the only LMWH other than enoxaparin?

Output: nadroparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only LMWH other than enoxaparin?. ### Response: nadroparin.


Instruction: What has been reported in patients with renal insufficiency?

Output: bioaccumulation of dalteparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been reported in patients with renal insufficiency?. ### Response: bioaccumulation of dalteparin.


Instruction: What was shown to be correlated with CrCl when used in full therapeutic doses?

Output: nadroparin clearance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was shown to be correlated with CrCl when used in full therapeutic doses?. ### Response: nadroparin clearance.


Instruction: What did nadroparin clearance but not tinzaparin clearance not have?

Output: CrCl

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did nadroparin clearance but not tinzaparin clearance not have?. ### Response: CrCl.


Instruction: What was Table 6— LMWH Target Ranges for the Treatment of VTE?

Output: LMWH and Frequency of Administration Target Range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was Table 6— LMWH Target Ranges for the Treatment of VTE?. ### Response: LMWH and Frequency of Administration Target Range.


Instruction: How many times daily enoxaparin is given?

Output: Twice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times daily enoxaparin is given?. ### Response: Twice.


Instruction: What is given twice daily nadroparin?

Output: 0.6-1.0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is given twice daily nadroparin?. ### Response: 0.6-1.0.


Instruction: When is dalteparin given twice?

Output: daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is dalteparin given twice?. ### Response: daily.


Instruction: What is the abbreviation for daily dalteparin?

Output: 1.05

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the abbreviation for daily dalteparin?. ### Response: 1.05.


Instruction: How many times daily enoxaparin is taken?

Output: Twice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times daily enoxaparin is taken?. ### Response: Twice.


Instruction: What is a measured 4 h after LMWH administration?

Output: Twice daily enoxaparin 0.6-1.0Twice daily nadroparin 0.6-1.0Once daily dalteparin 1.05Once daily enoxaparin  .  1.0Once daily nadroparin 1.3Once daily tinzaparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a measured 4 h after LMWH administration?. ### Response: Twice daily enoxaparin 0.6-1.0Twice daily nadroparin 0.6-1.0Once daily dalteparin 1.05Once daily enoxaparin  .  1.0Once daily nadroparin 1.3Once daily tinzaparin.


Instruction: What are US pharmacists' effect as team members on patient care?

Output: systematic review and meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are US pharmacists' effect as team members on patient care?. ### Response: systematic review and meta-analyses.


Instruction: What is the name of the systematic review and meta-analyses that focus on pharmacists?

Output: S2.1-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analyses that focus on pharmacists?. ### Response: S2.1-2.


Instruction: Who is part of the health care team in ambulatory set-tings in 2010?

Output: pharmacists’ effect as team members on patient care: systematic review and meta-analyses. Med Care. 2010;48:923–33. S2.1-3. Fazel MT, Bagalagel A, Lee JK, et al. Impact of diabetes care by pharmacists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is part of the health care team in ambulatory set-tings in 2010?. ### Response: pharmacists’ effect as team members on patient care: systematic review and meta-analyses. Med Care. 2010;48:923–33. S2.1-3. Fazel MT, Bagalagel A, Lee JK, et al. Impact of diabetes care by pharmacists.


Instruction: What is part of the health care team in ambulatory set-tings?

Output: pharmacists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is part of the health care team in ambulatory set-tings?. ### Response: pharmacists.


Instruction: What is a systematic review and meta-analysis of?

Output: Comparative effectiveness of implementation strategies for blood pressure control in hypertensive patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis of?. ### Response: Comparative effectiveness of implementation strategies for blood pressure control in hypertensive patients.


Instruction: What is a systematic review and meta-analysis?

Output: Comparative effectiveness of implementation strategies for blood pressure control in hypertensive patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis?. ### Response: Comparative effectiveness of implementation strategies for blood pressure control in hypertensive patients.


Instruction: What is the name of the systematic review?

Output: Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review?. ### Response: Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus.


Instruction: Who is responsible for team-based care and improved blood pressure?

Output: Kravetz JD, Walsh RF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is responsible for team-based care and improved blood pressure?. ### Response: Kravetz JD, Walsh RF.


Instruction: What is a randomized, pragmatic trial of primary care-based, pharma-cist-physician collaborative medication-therapy management of hypertension?

Output: Clin Ther

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomized, pragmatic trial of primary care-based, pharma-cist-physician collaborative medication-therapy management of hypertension?. ### Response: Clin Ther.


Instruction: What is Hunt JS, Siemienczuk J, Pape G, et al.?

Output: A randomized controlled trial of team-based care: impact of physician-pharmacist collaboration on uncontrolled hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Hunt JS, Siemienczuk J, Pape G, et al.?. ### Response: A randomized controlled trial of team-based care: impact of physician-pharmacist collaboration on uncontrolled hypertension.


Instruction: What is the impact of physician-pharmacist collaboration on uncontrolled hypertension?

Output: -based care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of physician-pharmacist collaboration on uncontrolled hypertension?. ### Response: -based care.


Instruction: When did a randomized controlled trial of team-based care take place?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did a randomized controlled trial of team-based care take place?. ### Response: 2008.


Instruction: What is the collaborative model of work for the management of hypertension called?

Output: Team-based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the collaborative model of work for the management of hypertension called?. ### Response: Team-based.


Instruction: What is a randomized trial of the effect of community pharmacist and nurse care on improving blood pressure management in diabetes mellitus?

Output: study of cardiovascular risk intervention by pharmacists-hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomized trial of the effect of community pharmacist and nurse care on improving blood pressure management in diabetes mellitus?. ### Response: study of cardiovascular risk intervention by pharmacists-hypertension.


Instruction: What is SCRIP-HTN?

Output: cardiovascular risk intervention by pharmacists-hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SCRIP-HTN?. ### Response: cardiovascular risk intervention by pharmacists-hypertension.


Instruction: What is the name of the study of cardiovascular risk intervention by pharmacists-hypertension?

Output: diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study of cardiovascular risk intervention by pharmacists-hypertension?. ### Response: diabetes mellitus.


Instruction: How many patients with diabetes mellitus were studied in 2008?

Output: 168:2355–61

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with diabetes mellitus were studied in 2008?. ### Response: 168:2355–61.


Instruction: What model can be used to improve chronic care in an academic primary care practice?

Output: Teamlet Model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What model can be used to improve chronic care in an academic primary care practice?. ### Response: Teamlet Model.


Instruction: Kravetz JD, Walsh RF. What is team-based hypertension management to improve?

Output: blood pressure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kravetz JD, Walsh RF. What is team-based hypertension management to improve?. ### Response: blood pressure control.


Instruction: What is the name of the multidisciplinary risk assessment and management programme-Diabetes Mellitus?

Output: RAMP-DM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multidisciplinary risk assessment and management programme-Diabetes Mellitus?. ### Response: RAMP-DM.


Instruction: How long does RAMP-DM last?

Output: Five-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does RAMP-DM last?. ### Response: Five-year.


Instruction: What is RAMP DM?

Output: Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is RAMP DM?. ### Response: Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus.


Instruction: What is the name of the randomised controlled trial?

Output: Informed shared decision-making programme on the prevention of myocardial infarc-tion in type 2 diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial?. ### Response: Informed shared decision-making programme on the prevention of myocardial infarc-tion in type 2 diabetes.


Instruction: What type of infarc-tion is prevented in type 2 diabetes?

Output: myocardial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of infarc-tion is prevented in type 2 diabetes?. ### Response: myocardial.


Instruction: When was the BMJ open published?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the BMJ open published?. ### Response: 2015.


Instruction: What is the name of the organization that endorses the Heart Rhythm Society's Scientific Statement?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that endorses the Heart Rhythm Society's Scientific Statement?. ### Response: American Heart Association.


Instruction: What is Matthew E. Levison's specialty?

Output: MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Matthew E. Levison's specialty?. ### Response: MD.


Instruction: Matthew E. Levison, MD; Peter B. Lockhart, DDS; Frederick A. Masoudi, MD, MSPH; Eric J. Okum;Walter R. Wilson; Ann F. Bolger;N.A. Mark Estes III; MD, FAHA, FHRS; Michael Gewitz; Jane W. Newburger; Eleanor B. Schron, PhD, RN FAHA; Katherine B. Scharon; PhD, MPH; FAHA?

Output: outside

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Matthew E. Levison, MD; Peter B. Lockhart, DDS; Frederick A. Masoudi, MD, MSPH; Eric J. Okum;Walter R. Wilson; Ann F. Bolger;N.A. Mark Estes III; MD, FAHA, FHRS; Michael Gewitz; Jane W. Newburger; Eleanor B. Schron, PhD, RN FAHA; Katherine B. Scharon; PhD, MPH; FAHA?. ### Response: outside.


Instruction: Who is a member of the American Heart Association Rheumatic Fever,Endocarditis, and Kawasaki Disease Committee?

Output: Kathryn A. Taubert

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the American Heart Association Rheumatic Fever,Endocarditis, and Kawasaki Disease Committee?. ### Response: Kathryn A. Taubert.


Instruction: What is Eleanor B. Schron's profession?

Output: PhD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Eleanor B. Schron's profession?. ### Response: PhD.


Instruction: Who is on behalf of the Council on Cardiovascular Surgery and Anesthesia?

Output: Kathryn A. Taubert

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is on behalf of the Council on Cardiovascular Surgery and Anesthesia?. ### Response: Kathryn A. Taubert.


Instruction: What does CIED stand for?

Output: cardiovascular implantable electronic device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CIED stand for?. ### Response: cardiovascular implantable electronic device.


Instruction: What is the acronym for a cardiovascular implantable electronic device?

Output: CIED

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for a cardiovascular implantable electronic device?. ### Response: CIED.


Instruction: What can be life-threatening in CIEDs?

Output: CIED infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be life-threatening in CIEDs?. ### Response: CIED infections.


Instruction: What has prompted the study of all aspects?

Output: CIED infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has prompted the study of all aspects?. ### Response: CIED infections.


Instruction: Who commissioned this scientific statement to educateclinicians?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who commissioned this scientific statement to educateclinicians?. ### Response: American Heart Association.


Instruction: What organization commissioned this statement to educateclinicians about CIED infections?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What organization commissioned this statement to educateclinicians about CIED infections?. ### Response: American Heart Association.


Instruction: What does this statement provide explicit recommendations for?

Output: the care of patients with suspected or establishedCIED infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does this statement provide explicit recommendations for?. ### Response: the care of patients with suspected or establishedCIED infections.


Instruction: In what year did the American Heart Association publish its Scientific Statement?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the American Heart Association publish its Scientific Statement?. ### Response: 2003.


Instruction: What year did the American Heart Association publish a statement that reviewed a variety of nonvalvularcardiovascular device infections?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the American Heart Association publish a statement that reviewed a variety of nonvalvularcardiovascular device infections?. ### Response: 2003.


Instruction: What was the primary focus of the statement?

Output: to formally recognize this group of cardiovas-cular infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary focus of the statement?. ### Response: to formally recognize this group of cardiovas-cular infections.


Instruction: What was the purpose of the document?

Output: to formally recognize this group of cardiovas-cular infections and to highlight their clinical importance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the purpose of the document?. ### Response: to formally recognize this group of cardiovas-cular infections and to highlight their clinical importance.


Instruction: What did the document include in regards to nonvalvu-lar device infections?

Output: a limited number of recommenda-tions regarding the prevention and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the document include in regards to nonvalvu-lar device infections?. ### Response: a limited number of recommenda-tions regarding the prevention and management.


Instruction: What was not indicated in patients with routine dental, gastrointestinal, and genitouri-nary procedures?

Output: antibioticprophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not indicated in patients with routine dental, gastrointestinal, and genitouri-nary procedures?. ### Response: antibioticprophylaxis.


Instruction: What does the American Heart Association do to avoid conflicts of interest?

Output: every effort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American Heart Association do to avoid conflicts of interest?. ### Response: every effort.


Instruction: What are the 2018 Cholesterol Clinical Practice Guidelines?

Output: Grundy et al 2018 Cholesterol Clinical Practice GuidelinesJune 18/25, 2019 Circulation. 2019;139:e1082–e1143. DOI: 10.1161/CIR.0000000000000625 e1128CLINICAL STATEMENTS  AND GUIDELINES S4.2-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2018 Cholesterol Clinical Practice Guidelines?. ### Response: Grundy et al 2018 Cholesterol Clinical Practice GuidelinesJune 18/25, 2019 Circulation. 2019;139:e1082–e1143. DOI: 10.1161/CIR.0000000000000625 e1128CLINICAL STATEMENTS  AND GUIDELINES S4.2-9.


Instruction: What is the DOI of the 2018 CLINICAL STATEMENTS AND GUIDELINES S4.2-9?

Output: 10.1161/CIR.0000000000000625 e1128

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI of the 2018 CLINICAL STATEMENTS AND GUIDELINES S4.2-9?. ### Response: 10.1161/CIR.0000000000000625 e1128.


Instruction: What is a systematic review and meta-analysis of interventions?

Output: Association between lower -ing LDL-C and cardiovascular risk reduction among different thera-peutic interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review and meta-analysis of interventions?. ### Response: Association between lower -ing LDL-C and cardiovascular risk reduction among different thera-peutic interventions.


Instruction: What is the name of the study that evaluated interventions in hypercholesterolemia?

Output: RUTHERFORD-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated interventions in hypercholesterolemia?. ### Response: RUTHERFORD-2.


Instruction: In what year did N Engl J Med publish 358:1431–43?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did N Engl J Med publish 358:1431–43?. ### Response: 2008.


Instruction: What drug was added to com-bination therapy in patients with familial hypercholesterolemia?

Output: Colesevelam

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was added to com-bination therapy in patients with familial hypercholesterolemia?. ### Response: Colesevelam.


Instruction: How long was the trial?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the trial?. ### Response: 5-year.


Instruction: What did Ross S, D'Mello M, Anand SS, et al. study?

Output: Effect of bile acid sequestrants on the risk of cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Ross S, D'Mello M, Anand SS, et al. study?. ### Response: Effect of bile acid sequestrants on the risk of cardiovascular events.


Instruction: How many patients with heterozygous familial hypercholesterolaemia were treated with alirocumab?

Output: 735

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with heterozygous familial hypercholesterolaemia were treated with alirocumab?. ### Response: 735.


Instruction: What is the name of the study that examined the risk of cardiovascular events?

Output: SAFEHEART Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the risk of cardiovascular events?. ### Response: SAFEHEART Registry.


Instruction: What is the SAFEHEART Registry?

Output: Spanish Familial Hypercholesterolemia Cohort Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the SAFEHEART Registry?. ### Response: Spanish Familial Hypercholesterolemia Cohort Study.


Instruction: What is evo-locumab?

Output: AMG 145

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evo-locumab?. ### Response: AMG 145.


Instruction: What drug inhibits PCSK9 in heterozygous familial hypercholesterolaemia?

Output: evo-locumab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug inhibits PCSK9 in heterozygous familial hypercholesterolaemia?. ### Response: evo-locumab.


Instruction: What is another name for evo-locumab?

Output: AMG 145

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for evo-locumab?. ### Response: AMG 145.


Instruction: In what year was the Lancet 385:331–40 published?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Lancet 385:331–40 published?. ### Response: 2015.


Instruction: What does VOYAGER do to lower levels of atherogenic lipids?

Output: increasing dose of atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does VOYAGER do to lower levels of atherogenic lipids?. ### Response: increasing dose of atorvastatin.


Instruction: What is a quantitative approach to determining when to add nonstatin therapy?

Output: Determining when to add nonstatin therapy: a quantitative approach. J Am Coll Cardiol. 2016;68:2412–21. S4.2-19. Vallejo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a quantitative approach to determining when to add nonstatin therapy?. ### Response: Determining when to add nonstatin therapy: a quantitative approach. J Am Coll Cardiol. 2016;68:2412–21. S4.2-19. Vallejo.


Instruction: What is the purpose of low-density lipo-protein cholesterol lowering?

Output: primary prevention of cardio-vascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of low-density lipo-protein cholesterol lowering?. ### Response: primary prevention of cardio-vascular disease.


Instruction: What is the name of the West of Scotland Coronary Prevention Study?

Output: WOSCOPS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the West of Scotland Coronary Prevention Study?. ### Response: WOSCOPS.


Instruction: How long did the WOSCOPS study last?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the WOSCOPS study last?. ### Response: 5-year.


Instruction: What is ezetimibe for?

Output: secondary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ezetimibe for?. ### Response: secondary prevention.


Instruction: What are stratification and ezetimibe for?

Output: secondary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are stratification and ezetimibe for?. ### Response: secondary prevention.


Instruction: What is the name of the disease that affects adults with diabetes?

Output: Diabetes Mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects adults with diabetes?. ### Response: Diabetes Mellitus.


Instruction: What did both people with heart failure and health professionals feel was fragmented?

Output: heart failure care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did both people with heart failure and health professionals feel was fragmented?. ### Response: heart failure care.


Instruction: What did NICE 2018 all rights reserved?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did NICE 2018 all rights reserved?. ### Response: Chronic Heart Failure.


Instruction: What did fragmented care lead to?

Output: lack of continuity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did fragmented care lead to?. ### Response: lack of continuity.


Instruction: What did patients who experienced lack of continuity find difficult to form?

Output: therapeutic relationships

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients who experienced lack of continuity find difficult to form?. ### Response: therapeutic relationships.


Instruction: How many studies were based on this sub-finding?

Output: four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were based on this sub-finding?. ### Response: four.


Instruction: What did patients who were 65 and under say led to encounters with professionals appearing anonymous?

Output: lack of continuity som etimes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients who were 65 and under say led to encounters with professionals appearing anonymous?. ### Response: lack of continuity som etimes.


Instruction: How many studies were based on?

Output: four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were based on?. ### Response: four.


Instruction: How many papers were rated serious limitations?

Output: Two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many papers were rated serious limitations?. ### Response: Two.


Instruction: What was one paper rated as moderate limitations due to lack of context?

Output: data richness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was one paper rated as moderate limitations due to lack of context?. ### Response: data richness.


Instruction: What was one paper rated as minor limitations?

Output: One paper was rated as moderate limitations due to lack of context and data richness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was one paper rated as minor limitations?. ### Response: One paper was rated as moderate limitations due to lack of context and data richness.


Instruction: Coherence was rated no or very minor concerns overall.

Output: Agreement between papers was good and appeared to fit well with related findings in other studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Coherence was rated no or very minor concerns overall.. ### Response: Agreement between papers was good and appeared to fit well with related findings in other studies.


Instruction: What did agreement between papers fit well with?

Output: related findings in other studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did agreement between papers fit well with?. ### Response: related findings in other studies.


Instruction: What was rated as minor concerns?

Output: Relevance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as minor concerns?. ### Response: Relevance.


Instruction: What was the relevance of the sub -finding to the focus of the review?

Output: high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the relevance of the sub -finding to the focus of the review?. ### Response: high.


Instruction: The focus of the review was what?

Output: Primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The focus of the review was what?. ### Response: Primary care.


Instruction: The concerns stemmed from two papers being from outside the UK and in what sub -set of CHF?

Output: a sub -set of CHF, and the data collection in a UK paper dating back to 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The concerns stemmed from two papers being from outside the UK and in what sub -set of CHF?. ### Response: a sub -set of CHF, and the data collection in a UK paper dating back to 2010.


Instruction: Data collection in a UK paper dating back to what year?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data collection in a UK paper dating back to what year?. ### Response: 2010.


Instruction: What was rated as no or very minor concerns?

Output: Adequacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was rated as no or very minor concerns?. ### Response: Adequacy.


Instruction: What was the sub -finding descriptive?

Output: Primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the sub -finding descriptive?. ### Response: Primary care.


Instruction: What was sufficient for the richness of data?

Output: The sub -finding was descriptive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was sufficient for the richness of data?. ### Response: The sub -finding was descriptive.


Instruction: The overall assessment of confidence was downgraded by one increment due to concerns in what?

Output: methodology and relevance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The overall assessment of confidence was downgraded by one increment due to concerns in what?. ### Response: methodology and relevance.


Instruction: What did people with heart failure and professionals working in heart failure care recognise?

Output: primary  care, and general practitioners in particular, could provide individualised care with continuity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did people with heart failure and professionals working in heart failure care recognise?. ### Response: primary  care, and general practitioners in particular, could provide individualised care with continuity.


Instruction: What could provide individualised care with continuity?

Output: general practitioners

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could provide individualised care with continuity?. ### Response: general practitioners.


Instruction: Who recognized that continuity is important to patients?

Output: People with heart failure and professionals working in heart failure care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who recognized that continuity is important to patients?. ### Response: People with heart failure and professionals working in heart failure care.


Instruction: What type of continuity is important to patients?

Output: individualised care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of continuity is important to patients?. ### Response: individualised care.


Instruction: What could happen if HF services take over a patient?

Output: cause patient s to lose touch with primary care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could happen if HF services take over a patient?. ### Response: cause patient s to lose touch with primary care.


Instruction: What model did GPs wish for?

Output: consultant” model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What model did GPs wish for?. ### Response: consultant” model.


Instruction: What type of model did they want?

Output: consultant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of model did they want?. ### Response: consultant.


Instruction: How did they wish for a consultant model?

Output: specialists answered questions and made recommendations, but did not take over care of the patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did they wish for a consultant model?. ### Response: specialists answered questions and made recommendations, but did not take over care of the patient.


Instruction: What is the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett et al 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular DiseaseSeptember 10, 2019 Circulation. 2019;140:e596–e646

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett et al 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular DiseaseSeptember 10, 2019 Circulation. 2019;140:e596–e646.


Instruction: What are the recommendations for Adults With High Blood Pressure or Hypertension adapted from?

Output: 2017 Hypertension Clinical Practice GuidelinesS4.4-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for Adults With High Blood Pressure or Hypertension adapted from?. ### Response: 2017 Hypertension Clinical Practice GuidelinesS4.4-1.


Instruction: What are two examples of nonpharmacological interventions for adults with elevated blood pressure or hypertension?

Output: weight lossS4.4-2–S4.4-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two examples of nonpharmacological interventions for adults with elevated blood pressure or hypertension?. ### Response: weight lossS4.4-2–S4.4-5.


Instruction: What are the Online Data Supplements 13 and 14.

Output: Recommendations for Adults With High Blood Pressure or HypertensionReferenced studies that support recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Online Data Supplements 13 and 14.. ### Response: Recommendations for Adults With High Blood Pressure or HypertensionReferenced studies that support recommendations.


Instruction: What are nonpharmacological interventions recommended to reduce BP?

Output: weight lossS4.4-2–S4.4-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are nonpharmacological interventions recommended to reduce BP?. ### Response: weight lossS4.4-2–S4.4-5.


Instruction: What is recommended to increase physical activity with structured exercise program?

Output: dietary potassium supplementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to increase physical activity with structured exercise program?. ### Response: dietary potassium supplementation.


Instruction: What is recommended for primary prevention of CVD?

Output: use of BP-lowering medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for primary prevention of CVD?. ### Response: use of BP-lowering medications.


Instruction: What is the estimated 10-year ASCVD risk* of 10% or higher?

Output: a BP target of less than 130/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the estimated 10-year ASCVD risk* of 10% or higher?. ### Response: a BP target of less than 130/80 mm Hg.


Instruction: How many mm Hg is the average diastolic BP?

Output: 80

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mm Hg is the average diastolic BP?. ### Response: 80.


Instruction: What is a BP target of less than 130/80 mm Hg recommended in adults with confirmed hypertension?

Output: treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a BP target of less than 130/80 mm Hg recommended in adults with confirmed hypertension?. ### Response: treatment.


Instruction: What is the recommended target for adults with a 10-year ASCVD event risk of 10% or higher?

Output: less than 130/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended target for adults with a 10-year ASCVD event risk of 10% or higher?. ### Response: less than 130/80 mm Hg.


Instruction: In adults with hypertension and chronic kidney disease, treatment to a BP goal of less than 130/80 mm Hg is what?

Output: reasonable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adults with hypertension and chronic kidney disease, treatment to a BP goal of less than 130/80 mm Hg is what?. ### Response: reasonable.


Instruction: In adult with T2DM and hypertension, antihypertensive drug is recommended.

Output: In adults with T2DM and hypertension, antihypertensive drug treatment should be initiated at a BP of 130/80 mm Hg or higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adult with T2DM and hypertension, antihypertensive drug is recommended.. ### Response: In adults with T2DM and hypertension, antihypertensive drug treatment should be initiated at a BP of 130/80 mm Hg or higher.


Instruction: What should antihypertensive drug treatment be initiated at in adults with T2DM and hypertension?

Output: BP of 130/80 mm Hg or higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should antihypertensive drug treatment be initiated at in adults with T2DM and hypertension?. ### Response: BP of 130/80 mm Hg or higher.


Instruction: What should a treatment goal be less than than 130/80 mm Hg?

Output: BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a treatment goal be less than than 130/80 mm Hg?. ### Response: BP.


Instruction: In adults with an estimated 10-year ASCVD risk 10% and an SBP of 140 mm Hg or higher, initiation and use of BP-lowering medication are recommended what?

Output: nonpharmacological interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adults with an estimated 10-year ASCVD risk 10% and an SBP of 140 mm Hg or higher, initiation and use of BP-lowering medication are recommended what?. ### Response: nonpharmacological interventions.


Instruction: What is the BP target in adults with confirmed hypertension without additional markers of increased ASCVD risk?

Output: less than 130/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the BP target in adults with confirmed hypertension without additional markers of increased ASCVD risk?. ### Response: less than 130/80 mm Hg.


Instruction: What is the name of the reference list for Chronic Heart Failure?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the reference list for Chronic Heart Failure?. ### Response: NICE 2018.


Instruction: What is a randomized controlled trial?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a randomized controlled trial?. ### Response: Chronic Heart Failure.


Instruction: How can chronic heart failure be improved by a nurse?

Output: monitored structured care progr am

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can chronic heart failure be improved by a nurse?. ### Response: monitored structured care progr am.


Instruction: What is eplerenone used for in patients at high risk for hyp erkalemia and/or worsening renal function?

Output: Safety and efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is eplerenone used for in patients at high risk for hyp erkalemia and/or worsening renal function?. ### Response: Safety and efficacy.


Instruction: What is EMPHASIS -HF?

Output: Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EMPHASIS -HF?. ### Response: Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure.


Instruction: What is the name of the EMPHASIS -HF study subgroups?

Output: Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the EMPHASIS -HF study subgroups?. ### Response: Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure.


Instruction: What was the Journal of the American College of Cardiology 62(17):1585-1593 114?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Journal of the American College of Cardiology 62(17):1585-1593 114?. ### Response: 2013.


Instruction: What does PRIMA stand for?

Output: PRo -brain -natriuretic peptide guided therapy of  chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PRIMA stand for?. ### Response: PRo -brain -natriuretic peptide guided therapy of  chronic heart failure.


Instruction: What is PRo -brain -natriuretic peptide guided therapy of chronic heart failure?

Output: Can PRo -brain -natriuretic peptide guided therapy of  chronic heart failure IMprove heart fAilure morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PRo -brain -natriuretic peptide guided therapy of chronic heart failure?. ### Response: Can PRo -brain -natriuretic peptide guided therapy of  chronic heart failure IMprove heart fAilure morbidity and mortality.


Instruction: What does guided therapy of chronic heart failure IMprove?

Output: heart fAilure morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does guided therapy of chronic heart failure IMprove?. ### Response: heart fAilure morbidity and mortality.