Instruction: What are some characteristic features of a traditional Mediterranean diet?

Output: high intake of vegetables, fruits, nuts, unrefined grains, and olive oil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some characteristic features of a traditional Mediterranean diet?. ### Response: high intake of vegetables, fruits, nuts, unrefined grains, and olive oil.


Instruction: In addition to fish and poultry, what other food is moderately ingested?

Output: wine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to fish and poultry, what other food is moderately ingested?. ### Response: wine.


Instruction: What was not reviewed as part of the 2014 VA/DoD HTN CPG update?

Output: New evi dence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not reviewed as part of the 2014 VA/DoD HTN CPG update?. ### Response: New evi dence.


Instruction: What did Toledo et al. evaluate the effects of a Mediterranean diet on on blood pressure in the PREDIMED trial in Spain?

Output: Statistically significant improvements in DBP,  but not SBP, were found for both intervention groups when compared to controls at four years. [132] Furthermore, the two groups randomized to the Mediterranean diet experienced a significant 28 -30% reduction in major cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Toledo et al. evaluate the effects of a Mediterranean diet on on blood pressure in the PREDIMED trial in Spain?. ### Response: Statistically significant improvements in DBP,  but not SBP, were found for both intervention groups when compared to controls at four years. [132] Furthermore, the two groups randomized to the Mediterranean diet experienced a significant 28 -30% reduction in major cardiovascular events.


Instruction: What was the name of the trial that included a large cohort of men and women at high cardiovascular risk?

Output: PREDIMED

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the trial that included a large cohort of men and women at high cardiovascular risk?. ### Response: PREDIMED.


Instruction: The two intervention groups received what?

Output: individual and group education

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The two intervention groups received what?. ### Response: individual and group education.


Instruction: What type of diet did the intervention groups receive?

Output: energy -unrestricted Mediterranean diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet did the intervention groups receive?. ### Response: energy -unrestricted Mediterranean diet.


Instruction: What kind of oil did the control group get?

Output: extra -virgin olive oil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What kind of oil did the control group get?. ### Response: extra -virgin olive oil.


Instruction: How did the two intervention groups educate themselves?

Output: on an energy -unrestricted Mediterranean diet from registered dietitians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the two intervention groups educate themselves?. ### Response: on an energy -unrestricted Mediterranean diet from registered dietitians.


Instruction: What did the two groups randomized to the Mediterranean diet experience a significant reduction in?

Output: major cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the two groups randomized to the Mediterranean diet experience a significant reduction in?. ### Response: major cardiovascular events.


Instruction: What was found to be statistically significant for both intervention groups at four years compared to controls?

Output: improvements in DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to be statistically significant for both intervention groups at four years compared to controls?. ### Response: improvements in DBP.


Instruction: What diet experienced a significant reduction in major cardiovascular events?

Output: Mediterranean

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What diet experienced a significant reduction in major cardiovascular events?. ### Response: Mediterranean.


Instruction: What did the Mediterranean diet experience?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Mediterranean diet experience?. ### Response: blood pressure.


Instruction: Why was the PREDIMED trial retracted and republished in 2018?

Output: issues with the randomization process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the PREDIMED trial retracted and republished in 2018?. ### Response: issues with the randomization process.


Instruction: How many household members were enrolled without randomization?

Output: One site

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many household members were enrolled without randomization?. ### Response: One site.


Instruction: How did one site enroll household members without randomization?

Output: assigned entire clinics  to an intervention group rather than individual participants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did one site enroll household members without randomization?. ### Response: assigned entire clinics  to an intervention group rather than individual participants.


Instruction: What did another site assign entire clinics to instead of individual participants?

Output: an intervention group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did another site assign entire clinics to instead of individual participants?. ### Response: an intervention group.


Instruction: A third site reported inconsistent use of what?

Output: randomization tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A third site reported inconsistent use of what?. ### Response: randomization tables.


Instruction: Data was reanalyzed to account for what within families or clinics?

Output: correlations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data was reanalyzed to account for what within families or clinics?. ### Response: correlations.


Instruction: What did the authors report after exclusion of participants known or suspected to have been improperly randomized?

Output: a reanalysis of data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the authors report after exclusion of participants known or suspected to have been improperly randomized?. ### Response: a reanalysis of data.


Instruction: The authors reported a reanalysis of data after what?

Output: exclusion of participants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The authors reported a reanalysis of data after what?. ### Response: exclusion of participants.


Instruction: What did the Work Group not systematically review as part of this guideline update?

Output: New evi dence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Work Group not systematically review as part of this guideline update?. ### Response: New evi dence.


Instruction: What is low based on evidence put forth in the 2014 VA/DoD HTN CPG?

Output: Confidence in the quality of evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low based on evidence put forth in the 2014 VA/DoD HTN CPG?. ### Response: Confidence in the quality of evidence.


Instruction: Issues with the randomization process of what?

Output: PREDIMED trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Issues with the randomization process of what?. ### Response: PREDIMED trial.


Instruction: What was the name of the VA/DoD HTN CPG?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the VA/DoD HTN CPG?. ### Response: 2014.


Instruction: What was reported as an issue with the randomization process?

Output: inconsistent use of randomization tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reported as an issue with the randomization process?. ### Response: inconsistent use of randomization tables.


Instruction: What was the key populati on exclusion criterion?

Output: Diagnostic screening for heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the key populati on exclusion criterion?. ### Response: Diagnostic screening for heart failure.


Instruction: What was diagnostic screening for in people who are asymptomatic?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was diagnostic screening for in people who are asymptomatic?. ### Response: heart failure.


Instruction: People with isolated right heart failure.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People with isolated right heart failure.. ### Response: .


Instruction: What is heart failure in people having chemotherapy?

Output: treatment for HIV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heart failure in people having chemotherapy?. ### Response: treatment for HIV.


Instruction: Who has treatment for HIV?

Output: Heart failure in people having treatment for HIV.   Heart failure in women who are pregnant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has treatment for HIV?. ### Response: Heart failure in people having treatment for HIV.   Heart failure in women who are pregnant.


Instruction: What is heart failure in women who are pregnant?

Output: Heart failure in people having treatment for HIV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heart failure in women who are pregnant?. ### Response: Heart failure in people having treatment for HIV.


Instruction: What is IE attributable to?

Output: Enterococcus spe-cies resistant to penicillin, aminoglycosides, and vancomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is IE attributable to?. ### Response: Enterococcus spe-cies resistant to penicillin, aminoglycosides, and vancomycin.


Instruction: What should be managed by specialists in infectious diseases, cardiology, cardiovascular surgery, clinical pharmacy and pediatrics?

Output: Patients with IE attributable to Enterococcus spe-cies resistant to penicillin, aminoglycosides, and vancomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be managed by specialists in infectious diseases, cardiology, cardiovascular surgery, clinical pharmacy and pediatrics?. ### Response: Patients with IE attributable to Enterococcus spe-cies resistant to penicillin, aminoglycosides, and vancomycin.


Instruction: What is considered necessary in pediatrics?

Output: ination therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered necessary in pediatrics?. ### Response: ination therapy.


Instruction: If daptomycin therapy is selected, how many mgkg124 h1 may be considered?

Output: 10 to 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If daptomycin therapy is selected, how many mgkg124 h1 may be considered?. ### Response: 10 to 12.


Instruction: What is the class of evidence C?

Output: Class IIb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of evidence C?. ### Response: Class IIb.


Instruction: In patients with persistent bacteremia or enterococcal strains, what may be combined therapy with?

Output: daptomycin and ampi-cillin or ceftaroline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with persistent bacteremia or enterococcal strains, what may be combined therapy with?. ### Response: daptomycin and ampi-cillin or ceftaroline.


Instruction: When is combination therapy with ampi-cillin or ceftaroline recommended?

Output: especially in patients with persistent bacteremia or enterococcal strains with high MICs (ie, 3 µg/mL) to daptomy-cin within the susceptible range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is combination therapy with ampi-cillin or ceftaroline recommended?. ### Response: especially in patients with persistent bacteremia or enterococcal strains with high MICs (ie, 3 µg/mL) to daptomy-cin within the susceptible range.


Instruction: What is the class IIb of daptomy-cin?

Output: Level of Evidence C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class IIb of daptomy-cin?. ### Response: Level of Evidence C.


Instruction: What is caused by fastidious Gram-negative bacilli of the HACEK group?

Output: HACEK MicroorganismsIE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is caused by fastidious Gram-negative bacilli of the HACEK group?. ### Response: HACEK MicroorganismsIE.


Instruction: How much of community-acquired NVE does Haemophilus species account for in patients who are not IDUs?

Output: ≈ 5% to 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of community-acquired NVE does Haemophilus species account for in patients who are not IDUs?. ### Response: ≈ 5% to 10%.


Instruction: What microorganisms grow slowly in standard blood cul-ture media?

Output: HACEK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What microorganisms grow slowly in standard blood cul-ture media?. ### Response: HACEK.


Instruction: Recovery may require what type of incubation?

Output: prolonged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recovery may require what type of incubation?. ### Response: prolonged.


Instruction: How many blood culture bottles show growth in patients with HACEK IE?

Output: only a small fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many blood culture bottles show growth in patients with HACEK IE?. ### Response: only a small fraction.


Instruction: What is highly suggestive of IE even without typical physical findings?

Output: Bacteremia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is highly suggestive of IE even without typical physical findings?. ### Response: Bacteremia.


Instruction: What group of microorganisms was previously uniformly susceptible to ampicillin?

Output: HACEK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group of microorganisms was previously uniformly susceptible to ampicillin?. ### Response: HACEK.


Instruction: What is appearing with increased frequency?

Output: amase–producing strains of HACEK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is appearing with increased frequency?. ### Response: amase–producing strains of HACEK.


Instruction: How can resistance occur in -lactamase-negative strains?

Output: resistance to ampicillin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can resistance occur in -lactamase-negative strains?. ### Response: resistance to ampicillin.


Instruction: Why is there difficulty in per forming antimicrobial susceptibility testing?

Output: failure of growth in in vitro susceptibility testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there difficulty in per forming antimicrobial susceptibility testing?. ### Response: failure of growth in in vitro susceptibility testing.


Instruction: In one survey, how many isolates did not grow adequately in control wells?

Output: 60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In one survey, how many isolates did not grow adequately in control wells?. ### Response: 60%.


Instruction: What is a common cause of failure of growth in in vitro susceptibility testing?

Output: difficulty in per -forming antimicrobial susceptibility testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of failure of growth in in vitro susceptibility testing?. ### Response: difficulty in per -forming antimicrobial susceptibility testing.


Instruction: In 1 survey, what percentage of isolates didn't grow adequately?

Output: 60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 1 survey, what percentage of isolates didn't grow adequately?. ### Response: 60%.


Instruction: Unless growth is adequate for in vivo screening, what microorganisms should be used?

Output: HACEK microorganisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Unless growth is adequate for in vivo screening, what microorganisms should be used?. ### Response: HACEK microorganisms.


Instruction: What should HACEK microorganisms be considered to be?

Output: consid-ered ampicillin resistant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should HACEK microorganisms be considered to be?. ### Response: consid-ered ampicillin resistant.


Instruction: What should not be used to treat patients with IE in these cases?

Output: penicillin and ampicillin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be used to treat patients with IE in these cases?. ### Response: penicillin and ampicillin.


Instruction: Almost all strains of the group are susceptible to what drug?

Output: ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Almost all strains of the group are susceptible to what drug?. ### Response: ceftriaxone.


Instruction: Ceftriaxone has commonly been used for what purpose?

Output: to treat HACEK IE220

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ceftriaxone has commonly been used for what purpose?. ### Response: to treat HACEK IE220.


Instruction: What has been used to treat HACEK IE220?

Output: Ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been used to treat HACEK IE220?. ### Response: Ceftriaxone.


Instruction: What is the duration of therapy for NVE?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the duration of therapy for NVE?. ### Response: 4 weeks.


Instruction: For PVE, what is reasonable?

Output: the duration of therapy of 6 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For PVE, what is reasonable?. ### Response: the duration of therapy of 6 weeks.


Instruction: Gentamicin is no longer recommended for what condition?

Output: neph

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Gentamicin is no longer recommended for what condition?. ### Response: neph.


Instruction: Why is Gentamicin no longer recommended?

Output: nephrotoxicity risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is Gentamicin no longer recommended?. ### Response: nephrotoxicity risks.


Instruction: Who is usually susceptible in vitro to fluo-roquinolones?

Output: The HACEK group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is usually susceptible in vitro to fluo-roquinolones?. ### Response: The HACEK group.


Instruction: What is an alternative agent in patients unable to tolerate ceftriaxone?

Output: flu-oroquinolone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an alternative agent in patients unable to tolerate ceftriaxone?. ### Response: flu-oroquinolone.


Instruction: As an alternative agent in patients unable to tolerate ceftriaxone?

Output: flu-oroquinolone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: As an alternative agent in patients unable to tolerate ceftriaxone?. ### Response: flu-oroquinolone.


Instruction: What is another third- or fourth-generation agent?

Output: cephalosporins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another third- or fourth-generation agent?. ### Response: cephalosporins.


Instruction: What do patients often seek information about?

Output: other aspects of their health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients often seek information about?. ### Response: other aspects of their health.


Instruction: What is one topic that frequently arises?

Output: possible restric-tions on sexual activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one topic that frequently arises?. ### Response: possible restric-tions on sexual activity.


Instruction: There are relatively limited scientific data on what?

Output: cardiovascular demands andpotential risks of sexual activity in patients with heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are relatively limited scientific data on what?. ### Response: cardiovascular demands andpotential risks of sexual activity in patients with heart disease.


Instruction: Data on the cardiovascular demands and risks of sexual activity in patients with heart disease date back how many decades?

Output: 3 or 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data on the cardiovascular demands and risks of sexual activity in patients with heart disease date back how many decades?. ### Response: 3 or 4.


Instruction: Most of the data on sexual activity are dealing with what type of person?

Output: men

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most of the data on sexual activity are dealing with what type of person?. ### Response: men.


Instruction: How many METs does sexual activity require?

Output: 3 to 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many METs does sexual activity require?. ### Response: 3 to 5.


Instruction: What is the equivalent of climbing?

Output: 2 flights of stairs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the equivalent of climbing?. ### Response: 2 flights of stairs.


Instruction: What is the equivalent of climbing 2 flights of stairs or walkingbriskly?

Output: 3 to 5 METs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the equivalent of climbing 2 flights of stairs or walkingbriskly?. ### Response: 3 to 5 METs.


Instruction: How many hours of sexual activity is associated with an average AMI?

Output: 1 to 2 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hours of sexual activity is associated with an average AMI?. ### Response: 1 to 2 hours.


Instruction: What is a strategy of selective or bailoutaspiration thrombecto my (Class IIb, LOE C-LD)?

Output: potential bene

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strategy of selective or bailoutaspiration thrombecto my (Class IIb, LOE C-LD)?. ### Response: potential bene.


Instruction: What is de fined as thromboectomythat was initially unplanned but later used during the procedure because of unsatisfactory initial result or procedural complication?

Output: Bailout

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is de fined as thromboectomythat was initially unplanned but later used during the procedure because of unsatisfactory initial result or procedural complication?. ### Response: Bailout.


Instruction: What type of thrombectomy has been demonstrated in patients with STEMI undergoingprimary PCI?

Output: routine rheolytic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of thrombectomy has been demonstrated in patients with STEMI undergoingprimary PCI?. ### Response: routine rheolytic.


Instruction: Who is the president of the American College of Cardiology?

Output: Shalom Jacobovitz

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the president of the American College of Cardiology?. ### Response: Shalom Jacobovitz.


Instruction: Who is the President of the American College of Cardiology?

Output: Shalom Jacobovitz

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the President of the American College of Cardiology?. ### Response: Shalom Jacobovitz.


Instruction: What is the name of the Chief Executive of ficer?

Output: Shalom Jacobovitz

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Chief Executive of ficer?. ### Response: Shalom Jacobovitz.


Instruction: Who was the Executive VicePresident of Science, Education, Quality and Publications?

Output: William J. Oetgen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the Executive VicePresident of Science, Education, Quality and Publications?. ### Response: William J. Oetgen.


Instruction: Who is the President of the American Heart Association?

Output: Mark A. Creager

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the President of the American Heart Association?. ### Response: Mark A. Creager.


Instruction: What is the title of the Director of Science and Clinical Policy?

Output: Lisa Brad ﬁeld

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the Director of Science and Clinical Policy?. ### Response: Lisa Brad ﬁeld.


Instruction: Who is the Senior VicePresident, Of fice of Science Operations?

Output: Gayle R. Whitman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Senior VicePresident, Of fice of Science Operations?. ### Response: Gayle R. Whitman.


Instruction: What is the name of the Task Force on Practice Guidelines?

Output: ACCF/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Practice Guidelines?. ### Response: ACCF/AHA.


Instruction: Where is the Metahodology Manual and Policies from the ACCF/AHA?

Output: Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Metahodology Manual and Policies from the ACCF/AHA?. ### Response: Task Force on Practice Guidelines.


Instruction: What is the name of the Committee on Standards for Developing Trust-worthy Clinical Practice Guidelines?

Output: Institute of Medi-cine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Committee on Standards for Developing Trust-worthy Clinical Practice Guidelines?. ### Response: Institute of Medi-cine.


Instruction: Where is the Institute of Medi-cine located?

Output: US

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Institute of Medi-cine located?. ### Response: US.


Instruction: What does the Committee for Systematic Reviewsof Comparative Effectiveness Research do?

Output: Finding What Works in Health Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Committee for Systematic Reviewsof Comparative Effectiveness Research do?. ### Response: Finding What Works in Health Care.


Instruction: Where is the Institute ofMedicine located?

Output: US

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Institute ofMedicine located?. ### Response: US.


Instruction: Where are the Standards for Systematic Reviews published?

Output: Washington, DC:National Academies Press

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are the Standards for Systematic Reviews published?. ### Response: Washington, DC:National Academies Press.


Instruction: Who published the ACC/AHA statement?

Output: American College of Cardiology/Amer-ican Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the ACC/AHA statement?. ### Response: American College of Cardiology/Amer-ican Heart Association.


Instruction: What is the name of the Task Force on PerformanceMeasures and Practice Guidelines?

Output: American College of Cardiology/Amer-ican Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on PerformanceMeasures and Practice Guidelines?. ### Response: American College of Cardiology/Amer-ican Heart Association.


Instruction: What are the names of the AHA/ACC/HHS strategies?

Output: Arnett DK, Goodman RA, Halperin JL, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the AHA/ACC/HHS strategies?. ### Response: Arnett DK, Goodman RA, Halperin JL, et al.


Instruction: What is the preferred agent for entero-coccal coverage for these patients?

Output: Amoxicillin or ampicillin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preferred agent for entero-coccal coverage for these patients?. ### Response: Amoxicillin or ampicillin.


Instruction: What may be administered to patients unable to tolerate ampicillin?

Output: Vancomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be administered to patients unable to tolerate ampicillin?. ### Response: Vancomycin.


Instruction: What type of infections are often polymicrobial?

Output: Regimens for Procedures on Infected Skin, SkinStructure, or Musculoskeletal Tissue

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of infections are often polymicrobial?. ### Response: Regimens for Procedures on Infected Skin, SkinStructure, or Musculoskeletal Tissue.


Instruction: What are the only bacteria that are likely to cause IE?

Output: staphylococciand/H9252-hemolytic streptococci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the only bacteria that are likely to cause IE?. ### Response: staphylococciand/H9252-hemolytic streptococci.


Instruction: What is an agent that is active against staphylococci and/or H9252-hemolytic streptococci?

Output: anantistaphylococcal penicillin or a cephalosporin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an agent that is active against staphylococci and/or H9252-hemolytic streptococci?. ### Response: anantistaphylococcal penicillin or a cephalosporin.


Instruction: What can beadministered to patients unable to tolerate a/H9252-lactam?

Output: Vancomycin or clindamycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can beadministered to patients unable to tolerate a/H9252-lactam?. ### Response: Vancomycin or clindamycin.


Instruction: What may be given to patients unable to tolerate a/H9252-lactam or who are suspected to have an infection caused by a methicillin-resistant strain of staphylococcus?

Output: Vancomycin or clindamycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be given to patients unable to tolerate a/H9252-lactam or who are suspected to have an infection caused by a methicillin-resistant strain of staphylococcus?. ### Response: Vancomycin or clindamycin.


Instruction: What are the previousAHA recommendations shown in?

Output: Table 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the previousAHA recommendations shown in?. ### Response: Table 6.


Instruction: What is prudent to select anantibiotic from a different class rather than to increase thedosage of antibiotic?

Output: If a patient is already receiving long-term antibiotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is prudent to select anantibiotic from a different class rather than to increase thedosage of antibiotic?. ### Response: If a patient is already receiving long-term antibiotic therapy.


Instruction: What is used to prevent the recurrence of acute rheumaticfever?

Output: antibioticregimens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to prevent the recurrence of acute rheumaticfever?. ### Response: antibioticregimens.


Instruction: What are antibioticregimens administered in lower than those recom-mended for the prevention of IE?

Output: dosages

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are antibioticregimens administered in lower than those recom-mended for the prevention of IE?. ### Response: dosages.


Instruction: What is more likely to cause IE than bacteremia associated with a dental procedure?

Output: bacteremia resulting from daily activities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more likely to cause IE than bacteremia associated with a dental procedure?. ### Response: bacteremia resulting from daily activities.


Instruction: What might be prevented by antibiotic prophylaxis?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be prevented by antibiotic prophylaxis?. ### Response: IE.


Instruction: What might be prevented by antibiotic prophylaxis even if it is 100% effective?

Output: IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be prevented by antibiotic prophylaxis even if it is 100% effective?. ### Response: IE.


Instruction: What is not recommended based solely on an increasedlifetime risk of acquisition of IE?

Output: Antibiotic prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended based solely on an increasedlifetime risk of acquisition of IE?. ### Response: Antibiotic prophylaxis.


Instruction: What type of prophylaxis is reasonable for all dental procedures that involve gingival tissues or periapical region of teeth or perforation oforal mucosa?

Output: Antibiotic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of prophylaxis is reasonable for all dental procedures that involve gingival tissues or periapical region of teeth or perforation oforal mucosa?. ### Response: Antibiotic.


Instruction: Patients with underlying cardiac conditions associated with the highest risk of adverse outcome should take what?

Output: Antibiotic prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with underlying cardiac conditions associated with the highest risk of adverse outcome should take what?. ### Response: Antibiotic prophylaxis.


Instruction: What is associated with the highest risk of adverse outcome from IE?

Output: underlying cardiac conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with the highest risk of adverse outcome from IE?. ### Response: underlying cardiac conditions.


Instruction: What is reasonable for procedures on respiratory tract or respiratory tract?

Output: Antibiotic prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for procedures on respiratory tract or respiratory tract?. ### Response: Antibiotic prophylaxis.


Instruction: What is the time system goal?

Output: 90 minutes or less

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the time system goal?. ### Response: 90 minutes or less.


Instruction: What should be performed in patients with STEMI and ischemic symptoms of less than 12 hours' duration?

Output: Primary PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed in patients with STEMI and ischemic symptoms of less than 12 hours' duration?. ### Response: Primary PCI.


Instruction: What are system goals?

Output: The proposed time windows

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are system goals?. ### Response: The proposed time windows.


Instruction: What should be made to provide reperfusion therapy as quickly as possible?

Output: every effort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be made to provide reperfusion therapy as quickly as possible?. ### Response: every effort.


Instruction: ACCF indicates American College of Cardiology Foundation; AHA, American Heart Association; ED, emergency department; EMS, what?

Output: emergency medical services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ACCF indicates American College of Cardiology Foundation; AHA, American Heart Association; ED, emergency department; EMS, what?. ### Response: emergency medical services.


Instruction: What is FMC?

Output: first medical contact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is FMC?. ### Response: first medical contact.


Instruction: What is LBBB?

Output: left bundle branch block

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LBBB?. ### Response: left bundle branch block.


Instruction: MI, myocardial infarction; PCI, percutaneous coronary intervention; what is STEMI?

Output: ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: MI, myocardial infarction; PCI, percutaneous coronary intervention; what is STEMI?. ### Response: ST-elevation myocardial infarction.


Instruction: What is the name of the book that treats heart failure chronic heart failure?

Output: NICE 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that treats heart failure chronic heart failure?. ### Response: NICE 2018.


Instruction: What are the results of the low sodium diet versus moderate sodium diet?

Output: Outcomes  No of Participants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the low sodium diet versus moderate sodium diet?. ### Response: Outcomes  No of Participants.


Instruction: What is GRADE?

Output: Quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GRADE?. ### Response: Quality of the evidence.


Instruction: How long is the time frame for the anticipated absolute effects?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the time frame for the anticipated absolute effects?. ### Response: 6 months.


Instruction: What is recommended for a moderate sodium diet?

Output: Advice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for a moderate sodium diet?. ### Response: Advice.


Instruction: What is the risk difference with Advice for low sodium diet (95% CI) Quality of Life Kansas City Cardiomyopathy Questionnaire Scale from: 0 to 100.

Output: High is worse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk difference with Advice for low sodium diet (95% CI) Quality of Life Kansas City Cardiomyopathy Questionnaire Scale from: 0 to 100.. ### Response: High is worse.


Instruction: What is better?

Output: High

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is better?. ### Response: High.


Instruction: Why is LOWa,b due to risk of bias?

Output: The me dian  quality of life in the control groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is LOWa,b due to risk of bias?. ### Response: The me dian  quality of life in the control groups.


Instruction: What was the median quality of life in the control groups?

Output: 70.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median quality of life in the control groups?. ### Response: 70.5.


Instruction: What was IQR in the intervention group?

Output: 4 lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was IQR in the intervention group?. ### Response: 4 lower.


Instruction: How much lower was umol/L?

Output: 7.8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much lower was umol/L?. ### Response: 7.8.


Instruction: Why was LOWa,b?

Output: risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was LOWa,b?. ### Response: risk of bias.


Instruction: What is the me dian renal function in the control groups?

Output: 106.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the me dian renal function in the control groups?. ### Response: 106.5.


Instruction: What is Creatinine (umol/L) 38 (1 study) 6 months  LOWa,b due to risk of bias?

Output: Renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Creatinine (umol/L) 38 (1 study) 6 months  LOWa,b due to risk of bias?. ### Response: Renal function.


Instruction: How many lower was the me dian renal function in the intervention groups?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many lower was the me dian renal function in the intervention groups?. ### Response: 4.


Instruction: How many increments were downgraded if the majority of the evidence was at high risk of bias?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were downgraded if the majority of the evidence was at high risk of bias?. ### Response: 2.


Instruction: If the evidence was at very high risk of bias, what could be assessed?

Output: LOWa,b,c due to risk of bias, indirectness, imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the evidence was at very high risk of bias, what could be assessed?. ### Response: LOWa,b,c due to risk of bias, indirectness, imprecision.


Instruction: Imprecision cannot be assessed due to reporting of what?

Output: median and inter -quartile range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Imprecision cannot be assessed due to reporting of what?. ### Response: median and inter -quartile range.


Instruction: What can be assessed because of reporting of median and inter-quartile range?

Output: Imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be assessed because of reporting of median and inter-quartile range?. ### Response: Imprecision.


Instruction: What does GRADE stand for?

Output: Quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does GRADE stand for?. ### Response: Quality of the evidence.


Instruction: How long is the time frame for fluid restriction for heart failure?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the time frame for fluid restriction for heart failure?. ### Response: 6 months.


Instruction: What is the risk with advice on fluid restriction?

Output: Risk difference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk with advice on fluid restriction?. ### Response: Risk difference.


Instruction: What percentage of the population is at risk with advice on fluid restriction?

Output: 6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the population is at risk with advice on fluid restriction?. ### Response: 6 months.


Instruction: What is the visual analogue scale of Quality of Life?

Output: EQ5D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the visual analogue scale of Quality of Life?. ### Response: EQ5D.


Instruction: How many studies were carried out in 6 months?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were carried out in 6 months?. ### Response: 1.


Instruction: Why was the risk of fluid restriction so low?

Output: risk of bias, indirectness, imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the risk of fluid restriction so low?. ### Response: risk of bias, indirectness, imprecision.


Instruction: Why was the mean quality of life at 6 months in the control groups 70.5?

Output: risk of bias, indirectness, imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the mean quality of life at 6 months in the control groups 70.5?. ### Response: risk of bias, indirectness, imprecision.


Instruction: What was the average quality of living at 6 month in the intervention groups 8.68 lower?

Output: 24.96 lower to 7.6 higher)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the average quality of living at 6 month in the intervention groups 8.68 lower?. ### Response: 24.96 lower to 7.6 higher).


Instruction: How much lower was the Oedema Congestion score in the intervention groups?

Output: 8.68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much lower was the Oedema Congestion score in the intervention groups?. ### Response: 8.68.


Instruction: What is the scale from: 0 to 5?

Output: High is worse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the scale from: 0 to 5?. ### Response: High is worse.


Instruction: How many studies were conducted?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were conducted?. ### Response: 1.


Instruction: Why was the mean  VERY LOWa,c,d?

Output: risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the mean  VERY LOWa,c,d?. ### Response: risk of bias.


Instruction: What was the mean congestion sore in the control groups?

Output: 1.18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean congestion sore in the control groups?. ### Response: 1.18.


Instruction: What did the intervention groups have a mean congestion score of 0.07?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the intervention groups have a mean congestion score of 0.07?. ### Response: higher.


Instruction: What was the minimum clinically significant benefit for a ‘positive’ outcome?

Output: a quality of life measure where a higher score denotes better health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the minimum clinically significant benefit for a ‘positive’ outcome?. ### Response: a quality of life measure where a higher score denotes better health.


Instruction: What is a quality of life measure where a higher score denotes better health?

Output: Chronic Heart Failure  Methods  © NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: 978 -1-4731 -3093 -7 52 minimum clinically significant benefit was positive for a ‘positive’ outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a quality of life measure where a higher score denotes better health?. ### Response: Chronic Heart Failure  Methods  © NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: 978 -1-4731 -3093 -7 52 minimum clinically significant benefit was positive for a ‘positive’ outcome.


Instruction: Where a higher score denotes better health), and negative for a ‘negative’ outcome?

Output: quality of life measure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where a higher score denotes better health), and negative for a ‘negative’ outcome?. ### Response: quality of life measure.


Instruction: What is the converse of clinically significant harms?

Output: half the median comparator group standard deviation of that variable will be taken as the MID

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the converse of clinically significant harms?. ### Response: half the median comparator group standard deviation of that variable will be taken as the MID.


Instruction: If baseline values are unavailable, then half the median comparator group standard deviation of that variable will be what?

Output: the MID

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If baseline values are unavailable, then half the median comparator group standard deviation of that variable will be what?. ### Response: the MID.


Instruction: What is the median comparator group standard deviation of a variable taken as?

Output: MID

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the median comparator group standard deviation of a variable taken as?. ### Response: MID.


Instruction: If standardised mean differen ces have been used, the MID will be set at the absolute value of what?

Output: +0.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If standardised mean differen ces have been used, the MID will be set at the absolute value of what?. ### Response: +0.5.


Instruction: Standardised mean differences are mean differences normalised to what standard?

Output: pooled standard deviation of the 2 groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Standardised mean differences are mean differences normalised to what standard?. ### Response: pooled standard deviation of the 2 groups.


Instruction: What are mean differences normalised to the pooled standard deviation of the 2 groups?

Output: standardised mean differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are mean differences normalised to the pooled standard deviation of the 2 groups?. ### Response: standardised mean differences.


Instruction: What is effectively expressed in units of ‘numbers of standard deviations’?

Output: standardised mean differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effectively expressed in units of ‘numbers of standard deviations’?. ### Response: standardised mean differences.


Instruction: The 0.5 MID value in this context indicates what?

Output: half a standard deviation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The 0.5 MID value in this context indicates what?. ### Response: half a standard deviation.


Instruction: What was the same definition of MID as used for non standardised mean differences?

Output: 0.5 MID value in this context therefore indicates half a standard deviation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the same definition of MID as used for non standardised mean differences?. ### Response: 0.5 MID value in this context therefore indicates half a standard deviation.


Instruction: What was subject to amendment after discussion with the committee?

Output: The default MID value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was subject to amendment after discussion with the committee?. ### Response: The default MID value.


Instruction: What was allowed if a decision was not influenced by bias towards making stronger or weaker recommendations for specific outcomes?

Output: MID level should be altered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was allowed if a decision was not influenced by bias towards making stronger or weaker recommendations for specific outcomes?. ### Response: MID level should be altered.


Instruction: What percentage of the CI of dichot omous outcomes was used?

Output: 95%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the CI of dichot omous outcomes was used?. ### Response: 95%.


Instruction: What is the 95% CI of dichot omous outcomes in a forest plot?

Output: Figure 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% CI of dichot omous outcomes in a forest plot?. ### Response: Figure 4.


Instruction: What would be pooled estimates and would not be placed on the same forest plot in practice?

Output: all 3 results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be pooled estimates and would not be placed on the same forest plot in practice?. ### Response: all 3 results.


Instruction: 4.3.4.1.5 Overall grading of the quality of clinical evidence Once an individual is evaluated, what is the grade?

Output: an overall quality grade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 4.3.4.1.5 Overall grading of the quality of clinical evidence Once an individual is evaluated, what is the grade?. ### Response: an overall quality grade.


Instruction: How was the grading of clinical evidence calculated?

Output: overall quality grade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the grading of clinical evidence calculated?. ### Response: overall quality grade.


Instruction: What was the overall quality grade calculated for?

Output: that outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall quality grade calculated for?. ### Response: that outcome.


Instruction: How were the scores from each of the main quality elements summed?

Output: to give a score that could be anything from 0 (the best possible) to −8 (the worst possible).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the scores from each of the main quality elements summed?. ### Response: to give a score that could be anything from 0 (the best possible) to −8 (the worst possible)..


Instruction: How were the main quality elements summed?

Output: Table 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the main quality elements summed?. ### Response: Table 4.


Instruction: What was the capped score?

Output: −3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the capped score?. ### Response: −3.


Instruction: How was the final score applied to the starting grade?

Output: by default

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the final score applied to the starting grade?. ### Response: by default.


Instruction: What was the grade that had originally been applied to the outcome by default?

Output: −3. This final score was t hen applied to the starting grade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the grade that had originally been applied to the outcome by default?. ### Response: −3. This final score was t hen applied to the starting grade.


Instruction: All RCTs started as High and the overall quality became Moderate, Low or Very Low if the overall score was 1, 2 or what?

Output: −3 points

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: All RCTs started as High and the overall quality became Moderate, Low or Very Low if the overall score was 1, 2 or what?. ### Response: −3 points.


Instruction: What are the reasons for downgrading in each case?

Output: footnotes of the GRADE tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the reasons for downgrading in each case?. ### Response: footnotes of the GRADE tables.


Instruction: What did non-randomised intervention studies start at?

Output: Low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did non-randomised intervention studies start at?. ### Response: Low.


Instruction: A score of 1 would be enough to take what grade?

Output: 0

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A score of 1 would be enough to take what grade?. ### Response: 0.


Instruction: What would be enough to take the grade to the lowest level of Very Low?

Output: a score of −1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be enough to take the grade to the lowest level of Very Low?. ### Response: a score of −1.


Instruction: What could be upgraded if there was a large magnitude of effect or a dose-respo nse gradient?

Output: Non -randomised intervention studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be upgraded if there was a large magnitude of effect or a dose-respo nse gradient?. ### Response: Non -randomised intervention studies.


Instruction: What is the overall quality of outcome evidence in GRADE Level Description High?

Output: Moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the overall quality of outcome evidence in GRADE Level Description High?. ### Response: Moderate.


Instruction: What is very unlikely to change our confidence in the estimate of effect?

Output: Further research

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is very unlikely to change our confidence in the estimate of effect?. ### Response: Further research.


Instruction: What is Related-Social-Needs-in-Clinical-Settings.pdf?

Output: Health literacy and cardiovascular disease: fundamental relevance to primary and sec-ondary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Related-Social-Needs-in-Clinical-Settings.pdf?. ### Response: Health literacy and cardiovascular disease: fundamental relevance to primary and sec-ondary prevention.


Instruction: What is the name of the systematic review of built environment, selected risk factors and major cardiovascular disease outcomes?

Output: PLoS ONE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of built environment, selected risk factors and major cardiovascular disease outcomes?. ### Response: PLoS ONE.


Instruction: When was PLoS ONE published?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was PLoS ONE published?. ### Response: 2016.


Instruction: What is the impact of individual cardiovascular risk factors and preventive therapies on the performance of the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort?

Output: Risk score overestimation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of individual cardiovascular risk factors and preventive therapies on the performance of the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort?. ### Response: Risk score overestimation.


Instruction: What did Berkowitz SA, Hulberg AC, Standish S, et al. address?

Output: unmet basic resource needs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Berkowitz SA, Hulberg AC, Standish S, et al. address?. ### Response: unmet basic resource needs.


Instruction: What is a part of chronic cardiometabolic disease manage-ment?

Output: Addressing unmet basic resource needs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a part of chronic cardiometabolic disease manage-ment?. ### Response: Addressing unmet basic resource needs.


Instruction: What is the JAMA Intern Med 2017177:244–52?

Output: Addressing unmet basic resource needs as part of chronic cardiometabolic disease manage-ment. JAMA Intern Med. 2017;177:244–52. S2.1-33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JAMA Intern Med 2017177:244–52?. ### Response: Addressing unmet basic resource needs as part of chronic cardiometabolic disease manage-ment. JAMA Intern Med. 2017;177:244–52. S2.1-33.


Instruction: Who is the author of the statement on cardiovascular health in African Americans?

Output: Carnethon

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the statement on cardiovascular health in African Americans?. ### Response: Carnethon.


Instruction: What is the current status of cardiovascu-lar disease and stroke in Hispanics/Latinos in the United States?

Output: a science advisory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current status of cardiovascu-lar disease and stroke in Hispanics/Latinos in the United States?. ### Response: a science advisory.


Instruction: What is a science advisory from the American Heart Association?

Output: Status of cardiovascu-lar disease and stroke in Hispanics/Latinos in the United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a science advisory from the American Heart Association?. ### Response: Status of cardiovascu-lar disease and stroke in Hispanics/Latinos in the United States.


Instruction: What is atherosclerotic cardiovascular disease in South Asians in the United States: epide-miology, risk factors, and treatments: a scientific statement from the American Heart Association?

Output: Atherosclerotic cardiovascular disease in South Asians in the United States: epide-miology, risk factors, and treatments: a scientific statement from the American Heart Association. Circulation. 2018;138:e1–34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atherosclerotic cardiovascular disease in South Asians in the United States: epide-miology, risk factors, and treatments: a scientific statement from the American Heart Association?. ### Response: Atherosclerotic cardiovascular disease in South Asians in the United States: epide-miology, risk factors, and treatments: a scientific statement from the American Heart Association. Circulation. 2018;138:e1–34.


Instruction: S2.1-36. Magnani JW, Mujahid MS, Aronow HD, et al. Health literacy and cardiovascular disease: fundamental relevance?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: S2.1-36. Magnani JW, Mujahid MS, Aronow HD, et al. Health literacy and cardiovascular disease: fundamental relevance?. ### Response: American Heart Association.


Instruction: What is the scientific statement from the American Heart Association about health literacy and cardiovascular disease?

Output: fundamental relevance to primary and sec-ondary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the scientific statement from the American Heart Association about health literacy and cardiovascular disease?. ### Response: fundamental relevance to primary and sec-ondary prevention.


Instruction: What is a novel determinant in the obesity epidemic?

Output: Body size misperception

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a novel determinant in the obesity epidemic?. ### Response: Body size misperception.


Instruction: What is a determinant in the obesity epidemic?

Output: Body size misperception

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a determinant in the obesity epidemic?. ### Response: Body size misperception.


Instruction: What is the US Department of Health and Human Services. Healthy People 2020. Washington, DC: 2010.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the US Department of Health and Human Services. Healthy People 2020. Washington, DC: 2010.. ### Response: https://www.healthypeople.gov.


Instruction: Who published Healthy People 2020?

Output: US Department of Health and Human Services

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published Healthy People 2020?. ### Response: US Department of Health and Human Services.


Instruction: Where did Human Services publish Healthy People 2030?

Output: Washington, DC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did Human Services publish Healthy People 2030?. ### Response: Washington, DC.


Instruction: What is the name of the website that Human Services made available to the public on January 3, 2019?

Output: healthypeople.gov

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the website that Human Services made available to the public on January 3, 2019?. ### Response: healthypeople.gov.


Instruction: Who wrote the umbrella review of Built and natural environment planning principles?

Output: Bird EL, Ige JO, Pilkington P ,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the umbrella review of Built and natural environment planning principles?. ### Response: Bird EL, Ige JO, Pilkington P ,.


Instruction: What is the name of the study that investigated neighborhood environ-ments and incident hypertension in the Multi-Ethnic Study of Atherosclerosis?

Output: Am J Epidemiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated neighborhood environ-ments and incident hypertension in the Multi-Ethnic Study of Atherosclerosis?. ### Response: Am J Epidemiol.


Instruction: What are the names of the research perspectives and priori-ties on Achieving healthy weight in African-American communities?

Output: Kumanyika SK, Gary TL, Lancaster KJ, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the research perspectives and priori-ties on Achieving healthy weight in African-American communities?. ### Response: Kumanyika SK, Gary TL, Lancaster KJ, et al.


Instruction: What is the research perspective of African-American communities?

Output: Achieving healthy weight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the research perspective of African-American communities?. ### Response: Achieving healthy weight.


Instruction: What is an opportunity to prevent cardiometabolic disease?

Output: Addressing sleep disturbances

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an opportunity to prevent cardiometabolic disease?. ### Response: Addressing sleep disturbances.


Instruction: Int Rev Psychiatry. 2014;26:155–76.

Output: Grandner MA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int Rev Psychiatry. 2014;26:155–76.. ### Response: Grandner MA.


Instruction: What is ACEi?

Output: ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACEi?. ### Response: ARB.


Instruction: What is ARB?

Output: RASi(ACEi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ARB?. ### Response: RASi(ACEi.


Instruction: Who judged that mostwell-informed patients would value kidney protection?

Output: the Work Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who judged that mostwell-informed patients would value kidney protection?. ### Response: the Work Group.


Instruction: What would mostwell-informed patients value the cardio- and renoprotective benefits of RASi over potential harms from AKI or hyperkalemia?

Output: beneﬁts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would mostwell-informed patients value the cardio- and renoprotective benefits of RASi over potential harms from AKI or hyperkalemia?. ### Response: beneﬁts.


Instruction: The HOPE study was one of the largest what?

Output: RASi studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The HOPE study was one of the largest what?. ### Response: RASi studies.


Instruction: What is creatinine?

Output: clearance <65 ml/min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is creatinine?. ### Response: clearance <65 ml/min.


Instruction: What is creatinine clearance 65 ml/min?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is creatinine clearance 65 ml/min?. ### Response: <.


Instruction: What was the mean follow-up for 4.5 years?

Output: n ¼3394

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean follow-up for 4.5 years?. ### Response: n ¼3394.


Instruction: How much did ACEi versus placebo reduce the risk for all-cause mortality?

Output: 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did ACEi versus placebo reduce the risk for all-cause mortality?. ### Response: 20%.


Instruction: How much of the patients in the HOPE study had diabetes?

Output: one-third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the patients in the HOPE study had diabetes?. ### Response: one-third.


Instruction: What percentage of patients had highBP?

Output: half

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients had highBP?. ### Response: half.


Instruction: How many patients had increasedalbuminuria?

Output: 9360

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had increasedalbuminuria?. ### Response: 9360.


Instruction: There were no studies evaluating the effect of what drug on kidney disease progression in patients with CKD without diabetes and A2?

Output: RASi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There were no studies evaluating the effect of what drug on kidney disease progression in patients with CKD without diabetes and A2?. ### Response: RASi.


Instruction: What is the best guide for this subpopulation?

Output: HOPE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the best guide for this subpopulation?. ### Response: HOPE.


Instruction: What did Cinotti et al. examine therole of lisinopril on in 131 patients without diabetic nephropathy over 22.5 months?

Output: progression of kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Cinotti et al. examine therole of lisinopril on in 131 patients without diabetic nephropathy over 22.5 months?. ### Response: progression of kidney disease.


Instruction: The mean baseline proteinuria per day was how many mg?

Output: 506

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The mean baseline proteinuria per day was how many mg?. ### Response: 506.


Instruction: How much was progression to dialysis orESKD reduced by 66%?

Output: The mean baseline proteinuria per day was506 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was progression to dialysis orESKD reduced by 66%?. ### Response: The mean baseline proteinuria per day was506 mg.


Instruction: What study compared telmisartan to placebo in high-risk patients?

Output: TRANSCENDstudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study compared telmisartan to placebo in high-risk patients?. ### Response: TRANSCENDstudy.


Instruction: What was the effect of the ARB on serum creatinine or ESKD?

Output: doubling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of the ARB on serum creatinine or ESKD?. ### Response: doubling.


Instruction: What did the study report in those with normal or mild albuminuria?

Output: detrimental kidneyeffects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the study report in those with normal or mild albuminuria?. ### Response: detrimental kidneyeffects.


Instruction: What type of outcomes with low event numbers apply?

Output: ter-tiary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of outcomes with low event numbers apply?. ### Response: ter-tiary.


Instruction: What is sparse evidence for other than RASi used asinitial therapy for highBP in people with CKD and moderately increased albuminuria (A2) without diabetes?

Output: slowing kidney disease progression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is sparse evidence for other than RASi used asinitial therapy for highBP in people with CKD and moderately increased albuminuria (A2) without diabetes?. ### Response: slowing kidney disease progression.


Instruction: Meto-prolol and amlodipine were not signi ficantly different in the AASK trial?

Output: fromramipril for the few CV events that occurred

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Meto-prolol and amlodipine were not signi ficantly different in the AASK trial?. ### Response: fromramipril for the few CV events that occurred.


Instruction: How many RCTs were there for MRAs?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs were there for MRAs?. ### Response: 3.


Instruction: How many par-ticipants were mainly from HF, not hypertension?

Output: 1426

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many par-ticipants were mainly from HF, not hypertension?. ### Response: 1426.


Instruction: What were not signi ficantly different from ramipril for the few CV events?

Output: meto-prolol and amlodipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were not signi ficantly different from ramipril for the few CV events?. ### Response: meto-prolol and amlodipine.


Instruction: How many par-ticipants mainly from HF, not hypertension, trials withdefined CKD subgroups?

Output: 1426

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many par-ticipants mainly from HF, not hypertension, trials withdefined CKD subgroups?. ### Response: 1426.


Instruction: Patients had varying levels of what?

Output: albu-minuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients had varying levels of what?. ### Response: albu-minuria.


Instruction: What did members of the writing group write and develop based on review of the articles?

Output: recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did members of the writing group write and develop based on review of the articles?. ### Response: recommendations.


Instruction: How manythirds agreement oneach recommendation?

Output: more than two thirds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How manythirds agreement oneach recommendation?. ### Response: more than two thirds.


Instruction: What allowed assessment of the level of evidence as recommended?

Output: The quality of information for agiven recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What allowed assessment of the level of evidence as recommended?. ### Response: The quality of information for agiven recommendation.


Instruction: What type of recommendation allowed assessment of the level of evidence as recommended by the American College ofCardiology Foundation/American Heart Association?

Output: quality of information for agiven recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of recommendation allowed assessment of the level of evidence as recommended by the American College ofCardiology Foundation/American Heart Association?. ### Response: quality of information for agiven recommendation.


Instruction: What were these clinical practice guidelines developed prior to?

Output: publication of “The American Association for Thoracic Surgery/Society ofThoracic Surgeons Position Statement on Developing Clinical PracticeDocuments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were these clinical practice guidelines developed prior to?. ### Response: publication of “The American Association for Thoracic Surgery/Society ofThoracic Surgeons Position Statement on Developing Clinical PracticeDocuments.


Instruction: On Developing Clinical PracticeDocuments, what did not strictly adhere to?

Output: process for CPGs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On Developing Clinical PracticeDocuments, what did not strictly adhere to?. ### Response: process for CPGs.


Instruction: What was the product of a lengthy and rigorous review by a multidisciplinary panel of experts?

Output: CPGs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the product of a lengthy and rigorous review by a multidisciplinary panel of experts?. ### Response: CPGs.


Instruction: Who approved all future STS CPGs appearing in TheAnnals of Thoracic Surgery?

Output: all three participating societies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who approved all future STS CPGs appearing in TheAnnals of Thoracic Surgery?. ### Response: all three participating societies.


Instruction: The Society of Thoracic Surgeons requests that this document be cited as follows: Shore-Lesserson L, Baker RA, Ferraris VA, Greilich PE, FitzgeraldD, Roman P, Hammon JW.

Output: Journal of ExtraCorporeal Technology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Society of Thoracic Surgeons requests that this document be cited as follows: Shore-Lesserson L, Baker RA, Ferraris VA, Greilich PE, FitzgeraldD, Roman P, Hammon JW.. ### Response: Journal of ExtraCorporeal Technology.


Instruction: Anesthesiologists and The American Society of Extra-Corporeal Technology: clinical practice guidelines —anticoagulation dur-ing cardiopulmonary bypass.

Output: Ann Thorac Surg 2018;105:650 –62

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anesthesiologists and The American Society of Extra-Corporeal Technology: clinical practice guidelines —anticoagulation dur-ing cardiopulmonary bypass.. ### Response: Ann Thorac Surg 2018;105:650 –62.


Instruction: What is the name of the department of anes-thesiology at Northshore University Hospital?

Output: Dr Shore-Lesserson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the department of anes-thesiology at Northshore University Hospital?. ### Response: Dr Shore-Lesserson.


Instruction: What can be viewed in the online version of this article?

Output: TheAppendix andSupplemental Tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be viewed in the online version of this article?. ### Response: TheAppendix andSupplemental Tables.


Instruction: What is the name of the organization that publishes the report?

Output: Elsevier Inc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that publishes the report?. ### Response: Elsevier Inc.


Instruction: How can physicians estimate operative risk for all CABG candidates?

Output: using a standard instru-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can physicians estimate operative risk for all CABG candidates?. ### Response: using a standard instru-ment.


Instruction: What is an example of a standard instru-ment?

Output: the risk calculator from the STS database

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a standard instru-ment?. ### Response: the risk calculator from the STS database.


Instruction: What has been recom-mendated in cases where the choice of revascularization isnot straightforward?

Output: Use of a Heart Team approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been recom-mendated in cases where the choice of revascularization isnot straightforward?. ### Response: Use of a Heart Team approach.


Instruction: What is also an important consideration in revas-cularization decisions?

Output: the abilityof the patient to tolerate and comply with dual antiplatelettherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is also an important consideration in revas-cularization decisions?. ### Response: the abilityof the patient to tolerate and comply with dual antiplatelettherapy.


Instruction: The 2005 PCI guideline8recommended what?

Output: routine angio-graphic follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The 2005 PCI guideline8recommended what?. ### Response: routine angio-graphic follow-up.


Instruction: What is an important consideration in revas-cularization decisions?

Output: the abilityof the patient to tolerate and comply with dual antiplatelettherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important consideration in revas-cularization decisions?. ### Response: the abilityof the patient to tolerate and comply with dual antiplatelettherapy.


Instruction: What was recommended 2 to 6 months after stenting for unprotectedleft main CAD?

Output: routine angio-graphic follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was recommended 2 to 6 months after stenting for unprotectedleft main CAD?. ### Response: routine angio-graphic follow-up.


Instruction: Why was the recommendation removed from the 2005 PCI guideline8?

Output: because angiography has limitedability to predict stent thrombosis and the results of SYNTAXsuggest good intermediate-term results for PCI in subjectswith left main CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the recommendation removed from the 2005 PCI guideline8?. ### Response: because angiography has limitedability to predict stent thrombosis and the results of SYNTAXsuggest good intermediate-term results for PCI in subjectswith left main CAD.


Instruction: When was the recommendation for PCI in subjects with left main CAD removed?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the recommendation for PCI in subjects with left main CAD removed?. ### Response: 2009.


Instruction: What was removed in the 2009 STEMI/PCI focused update?

Output: angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was removed in the 2009 STEMI/PCI focused update?. ### Response: angiography.


Instruction: What is more representative of patients in whom VKA therapy is well tolerated?

Output: patients already receiving VKA therapy at study entry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more representative of patients in whom VKA therapy is well tolerated?. ### Response: patients already receiving VKA therapy at study entry.


Instruction: In prespecifi ed subgroup analyses, the investigators did not find evidence of a difference in the effect of what on primary outcome?

Output: VKA therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In prespecifi ed subgroup analyses, the investigators did not find evidence of a difference in the effect of what on primary outcome?. ### Response: VKA therapy.


Instruction: What was the difference in the effect on major bleeding?

Output: -cant difference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference in the effect on major bleeding?. ### Response: -cant difference.


Instruction: What did the difference depend on whether patients were prior users of?

Output: VKA therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the difference depend on whether patients were prior users of?. ### Response: VKA therapy.


Instruction: What was associated with a nonsignifi cant trend toward a 69% relative increase in major bleeding compared with dual antiplatelet therapy?

Output: VKA therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a nonsignifi cant trend toward a 69% relative increase in major bleeding compared with dual antiplatelet therapy?. ### Response: VKA therapy.


Instruction: What was VKA therapy associated with at study entry?

Output: a nonsigniﬁ  cant trend toward a 24% relative decrease in major bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was VKA therapy associated with at study entry?. ### Response: a nonsigniﬁ  cant trend toward a 24% relative decrease in major bleeding.


Instruction: What was the relative decrease in major bleeding associated with dual antiplatelet therapy?

Output: 24%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the relative decrease in major bleeding associated with dual antiplatelet therapy?. ### Response: 24%.


Instruction: What was the name of the study that compared aspirin and clopid-ogrel therapy?

Output: ACTIVE A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that compared aspirin and clopid-ogrel therapy?. ### Response: ACTIVE A.


Instruction: How many patients were enrolled in the ACTIVE study?

Output: 7,554

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the ACTIVE study?. ### Response: 7,554.