Instruction: What is the impact of high normal blood pressure on the risk of cardiovascular disease?

Output: progression of coronary atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of high normal blood pressure on the risk of cardiovascular disease?. ### Response: progression of coronary atherosclerosis.


Instruction: When did N Engl J Med issue 345:1291-1297?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 345:1291-1297?. ### Response: 2001.


Instruction: What year did the N Engl J Med issue 345:1291–1297?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the N Engl J Med issue 345:1291–1297?. ### Response: 2001.


Instruction: Who is one of the Women's Health Initiative Investigators?

Output: Hsia J, Margolis KL, Eaton CB, Wenger NK, Allison M, Wu L, LaCroix AZ, Black HR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is one of the Women's Health Initiative Investigators?. ### Response: Hsia J, Margolis KL, Eaton CB, Wenger NK, Allison M, Wu L, LaCroix AZ, Black HR.


Instruction: What is the name of the organization that investigates prehypertension and cardiovascular disease risk?

Output: Women’s Health Initiative

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that investigates prehypertension and cardiovascular disease risk?. ### Response: Women’s Health Initiative.


Instruction: What is the impact of lower range of prehypertension on cardiovascular events in a general popula-tion?

Output: Hisayama Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of lower range of prehypertension on cardiovascular events in a general popula-tion?. ### Response: Hisayama Study.


Instruction: What is Canty JM Jr.'s title?

Output: 127

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Canty JM Jr.'s title?. ### Response: 127.


Instruction: What is the effect of hypertension and left ventricular hypertrophy on the lower range of coronary autoregulation?

Output: 128

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of hypertension and left ventricular hypertrophy on the lower range of coronary autoregulation?. ### Response: 128.


Instruction: What is the effect of angiotensin inhibition and coronary autoregulation in a canine model of LV hypertrophy?

Output: progression of coronary atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of angiotensin inhibition and coronary autoregulation in a canine model of LV hypertrophy?. ### Response: progression of coronary atherosclerosis.


Instruction: What is heterogeneity of myocardial blood flow called?

Output: Heterogeneity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heterogeneity of myocardial blood flow called?. ### Response: Heterogeneity.


Instruction: What is the definition of the concept of coronary flow reserve?

Output: Strauer BE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of the concept of coronary flow reserve?. ### Response: Strauer BE.


Instruction: What are the three types of blood pressure levels that affect the progression of heart disease?

Output: normal, pre-hypertensive, and hyper -tensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the three types of blood pressure levels that affect the progression of heart disease?. ### Response: normal, pre-hypertensive, and hyper -tensive.


Instruction: What is the effect of normal, pre-hypertensive, and hyper-tensed blood pressure levels on progression of coronary atherosclerosis?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of normal, pre-hypertensive, and hyper-tensed blood pressure levels on progression of coronary atherosclerosis?. ### Response: Effects.


Instruction: What was the J Am Coll Cardiol. 2006;48:833-838?

Output: blood pressure levels on progression of coronary atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol. 2006;48:833-838?. ### Response: blood pressure levels on progression of coronary atherosclerosis.


Instruction: How did Stewart IM determine the relationship of reduction in pressure to first myocardial infarc-tion in patients receiving treatment for hypertension?

Output: Relation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Stewart IM determine the relationship of reduction in pressure to first myocardial infarc-tion in patients receiving treatment for hypertension?. ### Response: Relation.


Instruction: What are the benefits and potential harms of lowering high blood pressure?

Output: Benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the benefits and potential harms of lowering high blood pressure?. ### Response: Benefits.


Instruction: What is a predictor of car -diac risk in patients with hypertension?

Output: pulse pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of car -diac risk in patients with hypertension?. ### Response: pulse pressure.


Instruction: What is the J-curve phenomenon and the treatment of hypertension?

Output: is there a point beyond which pressure reduction is dangerous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J-curve phenomenon and the treatment of hypertension?. ### Response: is there a point beyond which pressure reduction is dangerous.


Instruction: What is there a point beyond which pressure reduction is dangerous?

Output: The J-curve phenomenon and the treatment of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there a point beyond which pressure reduction is dangerous?. ### Response: The J-curve phenomenon and the treatment of hypertension.


Instruction: When was the JAMA 265:489–495.

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA 265:489–495.. ### Response: 1991.


Instruction: What was corrected for the regression dilution bias?

Output: prospective observational studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was corrected for the regression dilution bias?. ### Response: prospective observational studies.


Instruction: Blood pressure, stroke and coronary heart disease, part 1: prolonged differences in blood pressure?

Output: prospective observational studies corrected for the regression dilution bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood pressure, stroke and coronary heart disease, part 1: prolonged differences in blood pressure?. ### Response: prospective observational studies corrected for the regression dilution bias.


Instruction: What is the name of the cardiologist who performed the coronary revascularization?

Output: Rosendorff

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the cardiologist who performed the coronary revascularization?. ### Response: Rosendorff.


Instruction: What is one of the factors that determines the outcome of coronary intervention?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the factors that determines the outcome of coronary intervention?. ### Response: hypertension.


Instruction: What predicts cardiac prognosis in women with known or suspected ischemic heart disease?

Output: magnetic resonance results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts cardiac prognosis in women with known or suspected ischemic heart disease?. ### Response: magnetic resonance results.


Instruction: What does magnetic resonance results predict?

Output: cardiac prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does magnetic resonance results predict?. ### Response: cardiac prognosis.


Instruction: When was the J Am Coll Cardiol Car-diovasc Imaging 2:299–307.344?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol Car-diovasc Imaging 2:299–307.344?. ### Response: 2009.


Instruction: What is a branchblock?

Output: left bundle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a branchblock?. ### Response: left bundle.


Instruction: What is the name of the angiography used for prediction ofall-cause mortality?

Output: multide-tector coronary computed tomographic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the angiography used for prediction ofall-cause mortality?. ### Response: multide-tector coronary computed tomographic.


Instruction: When was the J Am Coll Cardiol published?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol published?. ### Response: 1992.


Instruction: What is incremental to clinical risk prediction in coronaryartery bypass patients with 64-slice computed tomography angiography?

Output: Prognostic assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is incremental to clinical risk prediction in coronaryartery bypass patients with 64-slice computed tomography angiography?. ### Response: Prognostic assessment.


Instruction: What is Chow BJ, Ahmed O, Small G, et al. Prognostic value of what?

Output: CTangiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chow BJ, Ahmed O, Small G, et al. Prognostic value of what?. ### Response: CTangiography.


Instruction: J Am Coll Cardiol Car-diovasc Imaging. 2011;4:496–502.348

Output: out

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Am Coll Cardiol Car-diovasc Imaging. 2011;4:496–502.348. ### Response: out.


Instruction: What is the study of myo-cardial perfusion and coronary anatomy imaging roles in CAD(SPARC): design, rationale, and baseline patient characteristics of aprospective, multicenter observational registry comparing PET,SPECT, and CTA for resource utilization and clinical outcomes?

Output: Hachamovitch R, Johnson JR, Hlatky MA, et al. The study of myo-cardial perfusion and coronary anatomy imaging roles in CAD(SPARC): design, rationale, and baseline patient characteristics of aprospective, multicenter observational registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the study of myo-cardial perfusion and coronary anatomy imaging roles in CAD(SPARC): design, rationale, and baseline patient characteristics of aprospective, multicenter observational registry comparing PET,SPECT, and CTA for resource utilization and clinical outcomes?. ### Response: Hachamovitch R, Johnson JR, Hlatky MA, et al. The study of myo-cardial perfusion and coronary anatomy imaging roles in CAD(SPARC): design, rationale, and baseline patient characteristics of aprospective, multicenter observational registry.


Instruction: What is a con-sensus statement of the Joint Steering Committees of the UnexplainedCardiac Arrest Registry of Europe and of the Idiopathic VentricularFibrillation Registry of the United States?

Output: Need for definition and standardized clinical evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a con-sensus statement of the Joint Steering Committees of the UnexplainedCardiac Arrest Registry of Europe and of the Idiopathic VentricularFibrillation Registry of the United States?. ### Response: Need for definition and standardized clinical evaluation.


Instruction: What is the Idiopathic VentricularFibrillation Registry of the United States?

Output: Steering Committees of the UnexplainedCardiac Arrest Registry of Europe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Idiopathic VentricularFibrillation Registry of the United States?. ### Response: Steering Committees of the UnexplainedCardiac Arrest Registry of Europe.


Instruction: When was the Circulation. 1997:95:265–72.350?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation. 1997:95:265–72.350?. ### Response: 1997.


Instruction: What does every NR, Fahrenbruch CE, Hallstrom AP, et al. say about the outcome of patients resuscitated after cardiac arrest?

Output: Influence of coronarybypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does every NR, Fahrenbruch CE, Hallstrom AP, et al. say about the outcome of patients resuscitated after cardiac arrest?. ### Response: Influence of coronarybypass surgery.


Instruction: How long did it take to develop a treatment plan for coronary artery disease?

Output: 15-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to develop a treatment plan for coronary artery disease?. ### Response: 15-year.


Instruction: What is the name of the study that investigated the effects of angiography on coronary heart failure?

Output: Coronary Artery SurgeryStudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effects of angiography on coronary heart failure?. ### Response: Coronary Artery SurgeryStudy.


Instruction: How long was the study?

Output: 15-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the study?. ### Response: 15-year.


Instruction: What does CASS stand for?

Output: Coronary Artery SurgeryStudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CASS stand for?. ### Response: Coronary Artery SurgeryStudy.


Instruction: What is the name of the registry that reports improved survival in triple vessel coronary artery disease and severe angina pectoris?

Output: Coronary Artery SurgeryStudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry that reports improved survival in triple vessel coronary artery disease and severe angina pectoris?. ### Response: Coronary Artery SurgeryStudy.


Instruction: When was the J Thorac Cardiovasc Surg. 97:487–95.354?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg. 97:487–95.354?. ### Response: 1989.


Instruction: What is a CASS registry study of survival in patients with triple-vessel disease and mild angina pectoris?

Output: Medical versus early surgicaltherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a CASS registry study of survival in patients with triple-vessel disease and mild angina pectoris?. ### Response: Medical versus early surgicaltherapy.


Instruction: When did Ann Thorac Surg. 1987 release 44:471–86.355.

Output: 1987

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ann Thorac Surg. 1987 release 44:471–86.355.. ### Response: 1987.


Instruction: When was the N Engl J Med released 364:1617–25.356?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med released 364:1617–25.356?. ### Response: 2011.


Instruction: Ischemic Left Ventricular Dysfunction.

Output: Myocardial Viability a ndSurvival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ischemic Left Ventricular Dysfunction.. ### Response: Myocardial Viability a ndSurvival.


Instruction: N Engl J Med.2011;364:1617–25.356.

Output: Myocardial Viability a ndSurvival in Ischemic Left Ventricular Dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: N Engl J Med.2011;364:1617–25.356.. ### Response: Myocardial Viability a ndSurvival in Ischemic Left Ventricular Dysfunction.


Instruction: What is the long-term survival in medicaltreated patients with ischaemic heart disease?

Output: prognostic importance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long-term survival in medicaltreated patients with ischaemic heart disease?. ### Response: prognostic importance.


Instruction: What is the name of the randomized controlled trial that evaluated home blood pressure monitoring and Web communication?

Output: a randomized controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial that evaluated home blood pressure monitoring and Web communication?. ### Response: a randomized controlled trial.


Instruction: When was the JAMA published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 2008.


Instruction: How many people were enrolled in the study?

Output: 218

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were enrolled in the study?. ### Response: 218.


Instruction: What is the name of the clinical pharmacist outreach program in patients with diabetes mellitus in 2 high-performing health systems?

Output: Heisler M, Hofer TP , Schmittdiel JA, et al. Improving blood pressure con-trol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the clinical pharmacist outreach program in patients with diabetes mellitus in 2 high-performing health systems?. ### Response: Heisler M, Hofer TP , Schmittdiel JA, et al. Improving blood pressure con-trol.


Instruction: What are the results of the adherence and intensification of medications cluster randomized, controlled pragmatic trial?

Output: Improving blood pressure con-trol through a clinical pharmacist outreach program in patients with dia-betes mellitus in 2 high-performing health systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the adherence and intensification of medications cluster randomized, controlled pragmatic trial?. ### Response: Improving blood pressure con-trol through a clinical pharmacist outreach program in patients with dia-betes mellitus in 2 high-performing health systems.


Instruction: What did Circulation do in 2012?

Output: Improving blood pressure con-trol through a clinical pharmacist outreach program in patients with dia-betes mellitus in 2 high-performing health systems: the adherence and intensification of medications cluster randomized, controlled pragmatic trial. Circulation. 2012;125:2863–72. 208. Liu S, Dunford SD, Leung YW, et al. Reducing blood pressure with Internet-based interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Circulation do in 2012?. ### Response: Improving blood pressure con-trol through a clinical pharmacist outreach program in patients with dia-betes mellitus in 2 high-performing health systems: the adherence and intensification of medications cluster randomized, controlled pragmatic trial. Circulation. 2012;125:2863–72. 208. Liu S, Dunford SD, Leung YW, et al. Reducing blood pressure with Internet-based interventions.


Instruction: What did Liu S, Dunford SD, Leung YW, et al. Reduce blood pressure with Internet-based interventions: a meta-analysis?

Output: 208

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Liu S, Dunford SD, Leung YW, et al. Reduce blood pressure with Internet-based interventions: a meta-analysis?. ### Response: 208.


Instruction: How did Omboni S, Gazzola T, Carabelli G, and others evaluate home blood pressure telemonitoring?

Output: Clinical usefulness and cost effec-tiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Omboni S, Gazzola T, Carabelli G, and others evaluate home blood pressure telemonitoring?. ### Response: Clinical usefulness and cost effec-tiveness.


Instruction: What is a valuable tool for hyper -tension management, a systematic review and meta-analysis?

Output: Telecare

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a valuable tool for hyper -tension management, a systematic review and meta-analysis?. ### Response: Telecare.


Instruction: What is the role of home blood pressure monitoring?

Output: overcoming therapeutic inertia and improving hyper -tension control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of home blood pressure monitoring?. ### Response: overcoming therapeutic inertia and improving hyper -tension control.


Instruction: What is the role of home blood pressure monitoring in overcoming therapeutic inertia and improving hyper -tension control?

Output: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of home blood pressure monitoring in overcoming therapeutic inertia and improving hyper -tension control?. ### Response: a systematic review and meta-analysis.


Instruction: Hypertension. 2011;57:29–38.212 Burke LE, Ma J, Azar KMJ, et al. Current science on consumer use of mo-bile health for cardiovascular disease prevention.

Output: 212. Burke LE, Ma J, Azar KMJ, et al. Current science on consumer use of mo-bile health for cardiovascular disease prevention: a scientific statement from the American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertension. 2011;57:29–38.212 Burke LE, Ma J, Azar KMJ, et al. Current science on consumer use of mo-bile health for cardiovascular disease prevention.. ### Response: 212. Burke LE, Ma J, Azar KMJ, et al. Current science on consumer use of mo-bile health for cardiovascular disease prevention: a scientific statement from the American Heart Association.


Instruction: What does the American Heart Association use for cardiovascular disease prevention?

Output: mo-bile health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American Heart Association use for cardiovascular disease prevention?. ### Response: mo-bile health.


Instruction: What is a new health system for the 21st century?

Output: Crossing the quality chasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new health system for the 21st century?. ### Response: Crossing the quality chasm.


Instruction: Where is the Institute of Medicine located?

Output: US

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Institute of Medicine located?. ### Response: US.


Instruction: What is the name of the organization that published the study on self-blood pressure monitoring?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that published the study on self-blood pressure monitoring?. ### Response: American Heart Association.


Instruction: What year did Academies Press publish the study?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Academies Press publish the study?. ### Response: 2001.


Instruction: How long did it take to obtain accurate blood pressure measurements?

Output: 35-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to obtain accurate blood pressure measurements?. ### Response: 35-year.


Instruction: What did a randomized clinical trial uti-lize the electronic health record?

Output: Self-blood pressure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a randomized clinical trial uti-lize the electronic health record?. ### Response: Self-blood pressure monitoring.


Instruction: What was the name of the study that investigated the relationship between clinic and ambulatory blood-pressure measurements and mortality?

Output: Banegas

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that investigated the relationship between clinic and ambulatory blood-pressure measurements and mortality?. ### Response: Banegas.


Instruction: Where can you find information about blood pressure at home?

Output: Web communication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find information about blood pressure at home?. ### Response: Web communication.


Instruction: What year did Diabetes Care publish a summary of revisions to standards of medical care in diabetes?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Diabetes Care publish a summary of revisions to standards of medical care in diabetes?. ### Response: 2016.


Instruction: What is the name of the website that provides information on monitoring your blood pressure at home?

Output: heart.org/en/health-topics/high-blood-pressure/understanding-blood-pressure-readings/monitoring-your-blood-pressure-at-home#.WcQNfLKGMnM. Accessed July 15, 2019. 218. American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the website that provides information on monitoring your blood pressure at home?. ### Response: heart.org/en/health-topics/high-blood-pressure/understanding-blood-pressure-readings/monitoring-your-blood-pressure-at-home#.WcQNfLKGMnM. Accessed July 15, 2019. 218. American Heart Association.


Instruction: Where can you find information on at home blood pressure monitoring?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find information on at home blood pressure monitoring?. ### Response: https://newsroom.heart.org.


Instruction: From whom did Ather and al92 with permission from Elsevier?

Output: Mosby, Inc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: From whom did Ather and al92 with permission from Elsevier?. ### Response: Mosby, Inc.


Instruction: Where was the copyright  2011, Mosby, Inc.Table 5. recommendations for the Treatment of Diabetes Mellitus in Stage A HF: Asymptomatic p atients at risk for HFreferenced Guideline referencesFor patients with diabetes mellitus, who are all at high risk for developing HF?

Output: Elsevier

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the copyright  2011, Mosby, Inc.Table 5. recommendations for the Treatment of Diabetes Mellitus in Stage A HF: Asymptomatic p atients at risk for HFreferenced Guideline referencesFor patients with diabetes mellitus, who are all at high risk for developing HF?. ### Response: Elsevier.


Instruction: What should be controlled in accordance with contemporary guidelines?

Output: blood sugar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be controlled in accordance with contemporary guidelines?. ### Response: blood sugar.


Instruction: What can be useful to prevent HF in patients at high risk for developing HF?

Output: ACE inhibitors or ARBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be useful to prevent HF in patients at high risk for developing HF?. ### Response: ACE inhibitors or ARBs.


Instruction: What is the acronym for ACE inhibitor?

Output: ARBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for ACE inhibitor?. ### Response: ARBs.


Instruction: What is B for ARBs for prevention of HF825, 27, 40, 49ACE?

Output: IIaA for ACE inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is B for ARBs for prevention of HF825, 27, 40, 49ACE?. ### Response: IIaA for ACE inhibitor.


Instruction: ARB is what?

Output: angiotensin-receptor blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ARB is what?. ### Response: angiotensin-receptor blocker.


Instruction: What is HF?

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HF?. ### Response: heart failure.


Instruction: What is LOE?

Output: Level of Evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LOE?. ### Response: Level of Evidence.


Instruction: When was this publication released?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication released?. ### Response: May 3, 2023.


Instruction: What year was the 2017 VA/SCD Guideline published?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the 2017 VA/SCD Guideline published?. ### Response: 2018.


Instruction: What is the name of the guideline published by Al-Khatib?

Output: VA/SCD Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline published by Al-Khatib?. ### Response: VA/SCD Guideline.


Instruction: Where is the National Academic Press located?

Output: Washington, DC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the National Academic Press located?. ### Response: Washington, DC.


Instruction: What is the current burden of cardiac arrest in the United States?

Output: S2.2.2-49

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current burden of cardiac arrest in the United States?. ### Response: S2.2.2-49.


Instruction: Who commissioned the paper on the Current Status and Future Directions?

Output: the Committee on the Treatment of Cardiac Arrest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who commissioned the paper on the Current Status and Future Directions?. ### Response: the Committee on the Treatment of Cardiac Arrest.


Instruction: What was the paper commissioned by the Committee on the Treatment of Cardiac Arrest?

Output: Current Status and Future Directions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the paper commissioned by the Committee on the Treatment of Cardiac Arrest?. ### Response: Current Status and Future Directions.


Instruction: What is the title of the 2015 issue of the journal Pulseless electric activity: definition, causes, mechanisms, management, and research priorities for the next decade?

Output: S2.2.2-

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the 2015 issue of the journal Pulseless electric activity: definition, causes, mechanisms, management, and research priorities for the next decade?. ### Response: S2.2.2-.


Instruction: What was the name of the workshop held by the National Heart, Lung, and Blood Institute?

Output: Pulseless electric activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the workshop held by the National Heart, Lung, and Blood Institute?. ### Response: Pulseless electric activity.


Instruction: What is the risk assessment of sudden cardiac arrest?

Output: population science and the individual risk mandate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk assessment of sudden cardiac arrest?. ### Response: population science and the individual risk mandate.


Instruction: What does the JAMA Cardiol. 2017:2:689–94?

Output: Sudden cardiac arrest risk assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the JAMA Cardiol. 2017:2:689–94?. ### Response: Sudden cardiac arrest risk assessment.


Instruction: Who is Bogle BM, Ning H, Mehrotra S, et al?

Output: Bogle BM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Bogle BM, Ning H, Mehrotra S, et al?. ### Response: Bogle BM.


Instruction: What are the causes of sudden car -diac death in the absence of previously identified heart disease?

Output: Temporal trends in the clinical and pathological characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the causes of sudden car -diac death in the absence of previously identified heart disease?. ### Response: Temporal trends in the clinical and pathological characteristics.


Instruction: What is the name of the journal that studies the temporal trends in the clinical and pathological characteristics of victims?

Output: Circ Arrhythm Electrophysiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the temporal trends in the clinical and pathological characteristics of victims?. ### Response: Circ Arrhythm Electrophysiol.


Instruction: When did the journal Circ Arrhythm Electrophysiol publish its findings?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the journal Circ Arrhythm Electrophysiol publish its findings?. ### Response: 2016.


Instruction: What is the cause of nonisch-emic sudden cardiac death in the current era?

Output: Temporal trends in the clinical and pathological characteristics of victims of sudden car -diac death in the absence of previously identified heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of nonisch-emic sudden cardiac death in the current era?. ### Response: Temporal trends in the clinical and pathological characteristics of victims of sudden car -diac death in the absence of previously identified heart disease.


Instruction: When did Heart Rhythm. 2011:8:1570-5. S2.2.2-54?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Heart Rhythm. 2011:8:1570-5. S2.2.2-54?. ### Response: 2011.


Instruction: What does Wong MK, Morrison LJ, Qiu F, et al. study?

Output: Trends in short- and long-term survival among out-of-hospital cardiac arrest patients alive at hospi-tal arrival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Wong MK, Morrison LJ, Qiu F, et al. study?. ### Response: Trends in short- and long-term survival among out-of-hospital cardiac arrest patients alive at hospi-tal arrival.


Instruction: How many patients are alive at hospi-tal arrival?

Output: out-of-hospital cardiac arrest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients are alive at hospi-tal arrival?. ### Response: out-of-hospital cardiac arrest.


Instruction: What is the name of the journal that studies the mechanisms of ventricular arrhythmias?

Output: Am J Physiol Heart Circ Physiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the mechanisms of ventricular arrhythmias?. ### Response: Am J Physiol Heart Circ Physiol.


Instruction: Who is the author of Mechanisms of VA S3.4-1?

Output: Cherry EM, Fenton FH, Gilmour RF Jr

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Mechanisms of VA S3.4-1?. ### Response: Cherry EM, Fenton FH, Gilmour RF Jr.


Instruction: The dynamics of cardiac fibrillation. Circ Res. 2013;112:849–62. Snoji Y, Heijman J, Nattel S, et al. Electrical storm: recent pathophysi-ological insights and what?

Output: therapeutic consequences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The dynamics of cardiac fibrillation. Circ Res. 2013;112:849–62. Snoji Y, Heijman J, Nattel S, et al. Electrical storm: recent pathophysi-ological insights and what?. ### Response: therapeutic consequences.


Instruction: Roden DM. Predicting drug-induced QT prolongation and torsades de pointes. J Physiol. 2016;594:2459–68.

Output: S3.4-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Roden DM. Predicting drug-induced QT prolongation and torsades de pointes. J Physiol. 2016;594:2459–68.. ### Response: S3.4-5.


Instruction: What is the role of late I Na in development of cardiac arrhythmias?

Output: The role of late I Na in development of cardiac arrhythmias. Handb Exp Pharmacol. 2014;221:137–68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of late I Na in development of cardiac arrhythmias?. ### Response: The role of late I Na in development of cardiac arrhythmias. Handb Exp Pharmacol. 2014;221:137–68.


Instruction: What does Lerman BB say about outflow tract tachycardia?

Output: Mechanism, diagnosis, and treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Lerman BB say about outflow tract tachycardia?. ### Response: Mechanism, diagnosis, and treatment.


Instruction: What is the name of the sarcoplasmic reticulum Ca2+ handling and arrhythmogenesis?

Output: Inherited dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the sarcoplasmic reticulum Ca2+ handling and arrhythmogenesis?. ### Response: Inherited dysfunction.


Instruction: Who is the author of Purkinje-related arrhythmias part I?

Output: Nogami A.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of Purkinje-related arrhythmias part I?. ### Response: Nogami A..


Instruction: What is the 2015 ACC/AHA/HRS SVT Guideline e5234?

Output: Page et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2015 ACC/AHA/HRS SVT Guideline e5234?. ### Response: Page et al.


Instruction: What is characterized as a focal AT?

Output: auto-matic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is characterized as a focal AT?. ### Response: auto-matic.


Instruction: What is focal AT characterized as?

Output: a fast rhythm from a discrete ori-gin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is focal AT characterized as?. ### Response: a fast rhythm from a discrete ori-gin.


Instruction: How much of the patients referred for SVT ablation have focal AT?

Output: 3% to 17%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the patients referred for SVT ablation have focal AT?. ### Response: 3% to 17%.


Instruction: What percentage of patients are referred for SVT ablation?

Output: 3% to 17%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients are referred for SVT ablation?. ### Response: 3% to 17%.


Instruction: What is the atrial rate during focal AT?

Output: between 100 and 250 bpm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the atrial rate during focal AT?. ### Response: between 100 and 250 bpm.


Instruction: What is focal AT usually between?

Output: 100 and 250 bpm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is focal AT usually between?. ### Response: 100 and 250 bpm.


Instruction: What are vari-able among patients during focal AT?

Output: Presence and severity of symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are vari-able among patients during focal AT?. ### Response: Presence and severity of symptoms.


Instruction: Focal AT in the adult population is usually associated with what?

Output: a benign prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Focal AT in the adult population is usually associated with what?. ### Response: a benign prognosis.


Instruction: AT-mediated cardiomyopathy has been reported in up to what percentage of patients referred for ablation of a tumor?

Output: 10%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AT-mediated cardiomyopathy has been reported in up to what percentage of patients referred for ablation of a tumor?. ### Response: 10%.


Instruction: What percentage of patients are referred for ablation of incessant SVT?

Output: 3% to 17%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients are referred for ablation of incessant SVT?. ### Response: 3% to 17%.


Instruction: Nonsustained focal AT is common and often does not require what?

Output: treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nonsustained focal AT is common and often does not require what?. ### Response: treatment.


Instruction: When is the diagnosis of focal AT suspected?

Output: when the ECG criteria are met

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the diagnosis of focal AT suspected?. ### Response: when the ECG criteria are met.


Instruction: What has been devel-oped to estimate the origin of the focal AT from?

Output: a discrete ori-gin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been devel-oped to estimate the origin of the focal AT from?. ### Response: a discrete ori-gin.


Instruction: What did devel-oped to estimate the origin of the focal AT from?

Output: a discrete ori-gin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did devel-oped to estimate the origin of the focal AT from?. ### Response: a discrete ori-gin.


Instruction: What is correlated to ATs arising from the left atrium?

Output: a positive P wave in lead V1 and negative P waves in leads I and aVL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is correlated to ATs arising from the left atrium?. ### Response: a positive P wave in lead V1 and negative P waves in leads I and aVL.


Instruction: Where do ATs arise from?

Output: left atrium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where do ATs arise from?. ### Response: left atrium.


Instruction: Positive P waves in leads II, III, and aVF suggest that the origin of AT is from where?

Output: cranial portion of either atria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Positive P waves in leads II, III, and aVF suggest that the origin of AT is from where?. ### Response: cranial portion of either atria.


Instruction: Shorter P-wave duration is correlated to AT arising from the paraseptal tissue versus what?

Output: the right or left atrial free wall

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Shorter P-wave duration is correlated to AT arising from the paraseptal tissue versus what?. ### Response: the right or left atrial free wall.


Instruction: What determines the precise location of the focal AT?

Output: mapping during EP studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What determines the precise location of the focal AT?. ### Response: mapping during EP studies.


Instruction: What is ultimately confirmed by mapping during EP studies when successful ablation is achieved?

Output: The precise location of the focal AT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ultimately confirmed by mapping during EP studies when successful ablation is achieved?. ### Response: The precise location of the focal AT.


Instruction: Focal AT has been localized to what?

Output: the crista terminalis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Focal AT has been localized to what?. ### Response: the crista terminalis.


Instruction: Where does focal AT originate more frequently than the left atrium?

Output: right atrium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does focal AT originate more frequently than the left atrium?. ### Response: right atrium.


Instruction: What can the underlying mechanism of focal AT be?

Output: auto-matic, triggered activity, or microreentry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can the underlying mechanism of focal AT be?. ### Response: auto-matic, triggered activity, or microreentry.


Instruction: What is of modest value because of limited sensi-tivity and specificity?

Output: methods to distinguish the mechanism through pharmacological testing or EP study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is of modest value because of limited sensi-tivity and specificity?. ### Response: methods to distinguish the mechanism through pharmacological testing or EP study.


Instruction: What can be tran-siently suppressed by adenosine or by overdrive pacing?

Output: An automatic AT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be tran-siently suppressed by adenosine or by overdrive pacing?. ### Response: An automatic AT.


Instruction: What may be terminated by beta blockers, diltiazem, or verapamil?

Output: An automatic AT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be terminated by beta blockers, diltiazem, or verapamil?. ### Response: An automatic AT.


Instruction: What can be induced and terminated?

Output: A microreentrant AT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be induced and terminated?. ### Response: A microreentrant AT.


Instruction: What is induced and terminated by programmed stimulation?

Output: A microreentrant AT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is induced and terminated by programmed stimulation?. ### Response: A microreentrant AT.


Instruction: What may depend on the location of the microreentrant?

Output: its response to adenosine, beta blockers, diltiazem, or vera-pamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may depend on the location of the microreentrant?. ### Response: its response to adenosine, beta blockers, diltiazem, or vera-pamil.


Instruction: What is the ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease: Executive SummaryCirculation. 2019;140:e563–e595.

Output: Arnett et al 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease: Executive SummaryCirculation. 2019;140:e563–e595.. ### Response: Arnett et al 2019.


Instruction: What are the Referenced studies that support recommendations summarized in?

Output: Online Data Supplements 17 and 18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Referenced studies that support recommendations summarized in?. ### Response: Online Data Supplements 17 and 18.


Instruction: What is low-dose aspirin?

Output: 75-100 mg orally daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low-dose aspirin?. ### Response: 75-100 mg orally daily.


Instruction: What might be considered for the primary prevention of ASCVD among select adults 40 to 70 years of age?

Output: Low-dose aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered for the primary prevention of ASCVD among select adults 40 to 70 years of age?. ### Response: Low-dose aspirin.


Instruction: What is low-dose aspirin orally daily?

Output: 75-100 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low-dose aspirin orally daily?. ### Response: 75-100 mg.


Instruction: What should not be administered on a routine basis for the primary prevention of ASCVD among adults >70 years of age?

Output: Low-dose aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be administered on a routine basis for the primary prevention of ASCVD among adults >70 years of age?. ### Response: Low-dose aspirin.


Instruction: What should low-dose aspirin be administered for?

Output: primary prevention of ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should low-dose aspirin be administered for?. ### Response: primary prevention of ASCVD.


Instruction: What should not be administered for the primary prevention of ASCVD among adults of any age who are at increased risk of bleeding?

Output: Low-dose aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be administered for the primary prevention of ASCVD among adults of any age who are at increased risk of bleeding?. ### Response: Low-dose aspirin.


Instruction: What is the growing need to consider value stems from?

Output: the goal of achieving the best possible health outcomes with finite healthcare resources in the pri-mary prevention of CVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the growing need to consider value stems from?. ### Response: the goal of achieving the best possible health outcomes with finite healthcare resources in the pri-mary prevention of CVD.


Instruction: What can be defined as the incremental health benefits of a therapy or procedure relative to its incremental net long-term costs?

Output: Value in healthcare

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be defined as the incremental health benefits of a therapy or procedure relative to its incremental net long-term costs?. ### Response: Value in healthcare.


Instruction: The consideration of cost and value in the guideline development process supports what?

Output: key goals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The consideration of cost and value in the guideline development process supports what?. ### Response: key goals.


Instruction: What is one of the goals of the guideline development process?

Output: consideration of cost and value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the goals of the guideline development process?. ### Response: consideration of cost and value.


Instruction: What are two of the key goals?

Output: ideal body weight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two of the key goals?. ### Response: ideal body weight.


Instruction: How is value assessment integrated into the US health-care system?

Output: inherent methodological chal-lenges

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is value assessment integrated into the US health-care system?. ### Response: inherent methodological chal-lenges.


Instruction: What type of chal-lenges are inherent in the integration of value assessments into our na-tional guidelines?

Output: methodological

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of chal-lenges are inherent in the integration of value assessments into our na-tional guidelines?. ### Response: methodological.


Instruction: Variability in costs across different settings and subgroups is an example of what?

Output: methodological chal-lenges

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Variability in costs across different settings and subgroups is an example of what?. ### Response: methodological chal-lenges.


Instruction: What is a type of variability over time?

Output: variability in who bears the burden of the health outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a type of variability over time?. ### Response: variability in who bears the burden of the health outcome.


Instruction: Who bears the burden of the health outcome?

Output: individual patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who bears the burden of the health outcome?. ### Response: individual patient.


Instruction: What is often spread beyond the individual to third-party pay-ers?

Output: healthcare cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often spread beyond the individual to third-party pay-ers?. ### Response: healthcare cost.


Instruction: What are the challenges specific to the prevention realm?

Output: variability in costs across different healthcare settings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the challenges specific to the prevention realm?. ### Response: variability in costs across different healthcare settings.


Instruction: What is the value of primordial and primary prevention in CVD?

Output: Low-dose aspirin (75-100 mg orally daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of primordial and primary prevention in CVD?. ### Response: Low-dose aspirin (75-100 mg orally daily.


Instruction: What is the best goal for most adults who are overweight?

Output: at least a 1-kg reduction in body weight

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the best goal for most adults who are overweight?. ### Response: at least a 1-kg reduction in body weight.


Instruction: How much reduction in body weight should you expect for every 1-kg reduction in weight?

Output: 1 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much reduction in body weight should you expect for every 1-kg reduction in weight?. ### Response: 1 mm Hg.


Instruction: What is a nonpharmacological intervention?

Output: Goal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a nonpharmacological intervention?. ### Response: Goal.


Instruction: How much Hg for every 1kg reduction in body weight is expected?

Output: 1 mm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much Hg for every 1kg reduction in body weight is expected?. ### Response: 1 mm.


Instruction: How much mm Hg is expected for every 1-kg reduction of body weight?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much mm Hg is expected for every 1-kg reduction of body weight?. ### Response: 1.


Instruction: What group of patients are not in the very high-risk group?

Output: NSTE-ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group of patients are not in the very high-risk group?. ### Response: NSTE-ACS.


Instruction: What is optional for patients with NSTE-ACS?

Output: an invasive study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is optional for patients with NSTE-ACS?. ### Response: an invasive study.


Instruction: What is optional for those at lower risk?

Output: an invasive study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is optional for those at lower risk?. ### Response: an invasive study.


Instruction: What can be safely deferred pending further clinical evidence?

Output: an invasive study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be safely deferred pending further clinical evidence?. ### Response: an invasive study.


Instruction: How can decisions about coronary angiography be individualized?

Output: on the basis of patient preferences and/or symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can decisions about coronary angiography be individualized?. ### Response: on the basis of patient preferences and/or symptoms.


Instruction: What can be individualized on the basis of patient preferences and/or symptoms?

Output: Decisions about coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be individualized on the basis of patient preferences and/or symptoms?. ### Response: Decisions about coronary angiography.


Instruction: What is recommended in low and intermediate-risk patients who have been free of ischemia at rest or with low-level activity?

Output: Noninvasive stress testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in low and intermediate-risk patients who have been free of ischemia at rest or with low-level activity?. ### Response: Noninvasive stress testing.


Instruction: What is useful in patients able to exercise in whom the ECG is free of resting ST changes that may interfere with interpretation?

Output: Treadmill exercise testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful in patients able to exercise in whom the ECG is free of resting ST changes that may interfere with interpretation?. ### Response: Treadmill exercise testing.


Instruction: How long have patients been free of ischemia at rest or with low-level activity?

Output: 12 to 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long have patients been free of ischemia at rest or with low-level activity?. ### Response: 12 to 24 hours.


Instruction: What can ST changes interfere with?

Output: in-terpretation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can ST changes interfere with?. ### Response: in-terpretation.


Instruction: What should be used in patients who are able to exercise but have ST changes on resting ECG that interfere with in-terpretation?

Output: Treadmill exercise testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used in patients who are able to exercise but have ST changes on resting ECG that interfere with in-terpretation?. ### Response: Treadmill exercise testing.


Instruction: What can add prognostic information to patients undergoing a low-level ex-ercise test?

Output: an imaging modality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can add prognostic information to patients undergoing a low-level ex-ercise test?. ### Response: an imaging modality.


Instruction: What is rec-ommended when physical limitations preclude ad-equate exercise stress?

Output: Pharmacological stress testing with imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rec-ommended when physical limitations preclude ad-equate exercise stress?. ### Response: Pharmacological stress testing with imaging.


Instruction: A noninvasive imaging test is recommended to evalu-ate what in patients with definite ACS?

Output: LV function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A noninvasive imaging test is recommended to evalu-ate what in patients with definite ACS?. ### Response: LV function.


Instruction: What is recommended to evalu-ate LV function in patients with definite ACS?

Output: A noninvasive imaging test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to evalu-ate LV function in patients with definite ACS?. ### Response: A noninvasive imaging test.


Instruction: The management of patients with NSTE-ACS requires what?

Output: con-tinuous risk stratification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The management of patients with NSTE-ACS requires what?. ### Response: con-tinuous risk stratification.


Instruction: Important prognostic information is derived from initial assessment, the patient's course during the early days of management, and the response to anti-ischemic and antithrombotic therapy?

Output: STE-ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Important prognostic information is derived from initial assessment, the patient's course during the early days of management, and the response to anti-ischemic and antithrombotic therapy?. ### Response: STE-ACS.


Instruction: What is the choice of stress test based on?

Output: the patient’s resting ECG and ability to exercise, local expertise, and available technologies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the choice of stress test based on?. ### Response: the patient’s resting ECG and ability to exercise, local expertise, and available technologies.


Instruction: What is low level or symptom-limited?

Output: exercise intensity of the treadmill test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low level or symptom-limited?. ### Response: exercise intensity of the treadmill test.


Instruction: Who determines the exercise intensity of the treadmill test?

Output: attending clinician

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who determines the exercise intensity of the treadmill test?. ### Response: attending clinician.


Instruction: What is used at the discretion of the attending clinician based on individual patient assessment?

Output: The exercise intensity of the treadmill test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used at the discretion of the attending clinician based on individual patient assessment?. ### Response: The exercise intensity of the treadmill test.


Instruction: For invasively managed patients with residual nonculprit lesions, additional evaluation may be indi-cated to ascertain the significance of such lesions?

Output: an invasive study is optional for those at lower risk and can be safely deferred pending further clinical evidence. Decisions about coronary angiography in patients who are not at high risk according to findings on clinical examination and noninvasive testing can be individualized on the basis of patient preferences and/or symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For invasively managed patients with residual nonculprit lesions, additional evaluation may be indi-cated to ascertain the significance of such lesions?. ### Response: an invasive study is optional for those at lower risk and can be safely deferred pending further clinical evidence. Decisions about coronary angiography in patients who are not at high risk according to findings on clinical examination and noninvasive testing can be individualized on the basis of patient preferences and/or symptoms.


Instruction: Refer to the PCI CPG for additional details.

Output: 264.5.1. Noninvasive Test SelectionThe goals of noninvasive testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Refer to the PCI CPG for additional details.. ### Response: 264.5.1. Noninvasive Test SelectionThe goals of noninvasive testing.


Instruction: What are the goals of noninvasive testing in patients with a low or intermediate likelihood of CAD and high-risk patients who did not have an early invasive strategy?

Output: to detect ischemia and estimate prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the goals of noninvasive testing in patients with a low or intermediate likelihood of CAD and high-risk patients who did not have an early invasive strategy?. ### Response: to detect ischemia and estimate prognosis.


Instruction: What information guides further diagnostic steps and therapeutic measures?

Output: Noninvasive Test Selection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What information guides further diagnostic steps and therapeutic measures?. ### Response: Noninvasive Test Selection.


Instruction: What is one reason for the simplicity of the procedure?

Output: lower cost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one reason for the simplicity of the procedure?. ### Response: lower cost.


Instruction: What is another reason why the procedure is more cost-effective?

Output: simplicity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another reason why the procedure is more cost-effective?. ### Response: simplicity.


Instruction: Why is the procedure more convenient?

Output: Treadmill exercise testing is useful in patients able to exercise in whom the ECG is free of resting ST changes that may interfere with interpretation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the procedure more convenient?. ### Response: Treadmill exercise testing is useful in patients able to exercise in whom the ECG is free of resting ST changes that may interfere with interpretation.


Instruction: What is the risk of undergoing target-vessel revascularization higher with stenting than with CABG?

Output: sig-nificantly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of undergoing target-vessel revascularization higher with stenting than with CABG?. ### Response: sig-nificantly.


Instruction: In the SYNTAX trial, what percentage of patients with unprotected left main CAD had complex disease that pre-vented randomization?

Output: 45%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the SYNTAX trial, what percentage of patients with unprotected left main CAD had complex disease that pre-vented randomization?. ### Response: 45%.


Instruction: What percentage of patients underwent CABG?

Output: 89%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients underwent CABG?. ### Response: 89%.


Instruction: How many of the 1800 patients with unprotected left main CAD were randomized to either DES or CABG in addition to DES?

Output: 705

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the 1800 patients with unprotected left main CAD were randomized to either DES or CABG in addition to DES?. ### Response: 705.


Instruction: What did the majority of patients with a low SYNTAX score have?

Output: isolated left main CAD or left main CAD plus 1-ves-sel CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the majority of patients with a low SYNTAX score have?. ### Response: isolated left main CAD or left main CAD plus 1-ves-sel CAD.


Instruction: What percentage of intermediates had left main CAD plus 2-vessel CAD?

Output: majority of those with an intermediate score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of intermediates had left main CAD plus 2-vessel CAD?. ### Response: majority of those with an intermediate score.


Instruction: Most intermediates with a high SYNTAX score had what?

Output: left main CAD plus 3-vessel CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most intermediates with a high SYNTAX score had what?. ### Response: left main CAD plus 3-vessel CAD.


Instruction: At 1 year, rates of what were higher?

Output: MACCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At 1 year, rates of what were higher?. ### Response: MACCE.


Instruction: What was performed more often in the DES group than in the CABG group?

Output: Repeat revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was performed more often in the DES group than in the CABG group?. ### Response: Repeat revascularization.


Instruction: At 1 year, rates of all-cause death and MACCE were similar among patients who had undergone what?

Output: DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At 1 year, rates of all-cause death and MACCE were similar among patients who had undergone what?. ### Response: DES.


Instruction: What was the percentage of strokes in the CABG group?

Output: 2.7% versus 0.3%).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the percentage of strokes in the CABG group?. ### Response: 2.7% versus 0.3%)..


Instruction: What group had the most strokes?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group had the most strokes?. ### Response: CABG.


Instruction: At 3 years of follow-up, what was the incidence of death in patients undergoing left main CAD revascularization with low or intermediate SYNTAX scores?

Output: 3.7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At 3 years of follow-up, what was the incidence of death in patients undergoing left main CAD revascularization with low or intermediate SYNTAX scores?. ### Response: 3.7%.


Instruction: What was the inci-dence of death after 3 years in those with a high SYNTAX score?

Output: 13.4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the inci-dence of death after 3 years in those with a high SYNTAX score?. ### Response: 13.4%.


Instruction: How much after DES was there an increase in death in those who had high scores?

Output: 13.4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much after DES was there an increase in death in those who had high scores?. ### Response: 13.4%.


Instruction: Why was the primary endpoint of the overall SYNTAX trial not met?

Output: noninferiority com-parison of CABG and DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the primary endpoint of the overall SYNTAX trial not met?. ### Response: noninferiority com-parison of CABG and DES.


Instruction: What was the primary endpoint of the overall SYNTAX trial not met?

Output: noninferiority com-parison of CABG and DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary endpoint of the overall SYNTAX trial not met?. ### Response: noninferiority com-parison of CABG and DES.


Instruction: The results of subgroup analyses need to be applied with what?

Output: caution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The results of subgroup analyses need to be applied with what?. ### Response: caution.


Instruction: At 5 years of fol-low-up, MACCE rates did not differ significantly between groups of patients with what scores?

Output: low or intermediate SYNTAX scores

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At 5 years of fol-low-up, MACCE rates did not differ significantly between groups of patients with what scores?. ### Response: low or intermediate SYNTAX scores.


Instruction: What group had significantly more patients with high SYNTAX scores?

Output: DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group had significantly more patients with high SYNTAX scores?. ### Response: DES.


Instruction: What is probably recommended in preference to PCI to improve survival?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is probably recommended in preference to PCI to improve survival?. ### Response: CABG.


Instruction: What type of graft can be anastomosed to the LAD artery?

Output: LIMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of graft can be anastomosed to the LAD artery?. ### Response: LIMA.


Instruction: What is recommended in patients with diabetes mellitus and multivessel CAD?

Output: A Heart Team approach to revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with diabetes mellitus and multivessel CAD?. ### Response: A Heart Team approach to revascularization.


Instruction: What type of revascularization is recommended in patients with diabetes mellitus and complex multivessel CAD?

Output: A Heart Team approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of revascularization is recommended in patients with diabetes mellitus and complex multivessel CAD?. ### Response: A Heart Team approach.


Instruction: What is generally recommended in preference to PCI to improve survival?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is generally recommended in preference to PCI to improve survival?. ### Response: CABG.


Instruction: What is likely to improve survival?

Output: revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is likely to improve survival?. ### Response: revascularization.


Instruction: What can be anastomosed to the LAD artery?

Output: LIMA graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be anastomosed to the LAD artery?. ### Response: LIMA graft.


Instruction: B)Modified recommendation (Class of Recommendation changed from IIa to I, wording changed, additional RCT added)

Output: 58–69

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: B)Modified recommendation (Class of Recommendation changed from IIa to I, wording changed, additional RCT added). ### Response: 58–69.


Instruction: What is NICE 2018?

Output: All rights reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: All rights reserved.


Instruction: What is the name of the study that NICE is focusing on?

Output: Atienza

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that NICE is focusing on?. ### Response: Atienza.


Instruction: Who is the author of NICE?

Output: 978 -1-4731 -3093 -7 348

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of NICE?. ### Response: 978 -1-4731 -3093 -7 348.


Instruction: How long does it take to follow up a patient?

Output: 2 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to follow up a patient?. ### Response: 2 year.


Instruction: What is QALY?

Output: quality -adjusted life years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is QALY?. ### Response: quality -adjusted life years.


Instruction: How many nurses are involved in a geriatrics case manager?

Output: two to four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many nurses are involved in a geriatrics case manager?. ### Response: two to four.


Instruction: What may not reflect current NHS context?

Output: Spanish resource use data and unit costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not reflect current NHS context?. ### Response: Spanish resource use data and unit costs.


Instruction: What is not used as the health outcome measure?

Output: QALYs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not used as the health outcome measure?. ### Response: QALYs.


Instruction: Atienza is 1 of how many studies included comparing MDT clinic to usual care in high risk patients?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atienza is 1 of how many studies included comparing MDT clinic to usual care in high risk patients?. ### Response: 5.


Instruction: No exploration of what?

Output: uncertainty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No exploration of what?. ### Response: uncertainty.


Instruction: What may Italian national health service resource use and unit costs may be?

Output: not

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may Italian national health service resource use and unit costs may be?. ### Response: not.


Instruction: What may not reflect current UK NHS context?

Output: Italian national health service resource use and unit costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not reflect current UK NHS context?. ### Response: Italian national health service resource use and unit costs.


Instruction: What was not reported clearly enough to report and therefore were not used as the health outcome measure?

Output: QAL Y data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not reported clearly enough to report and therefore were not used as the health outcome measure?. ### Response: QAL Y data.


Instruction: What is 1 of 5 studies included comparing MDT clinic to usual care in high risk patients?

Output: Pulignan o

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is 1 of 5 studies included comparing MDT clinic to usual care in high risk patients?. ### Response: Pulignan o.


Instruction: What does not reflect the full body of evidence available for this comparison?

Output: Within -trial analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not reflect the full body of evidence available for this comparison?. ### Response: Within -trial analysis.


Instruction: What is the difference between home -based MDT and n urse led MDT clinic?

Output: long  intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between home -based MDT and n urse led MDT clinic?. ### Response: long  intervention.


Instruction: What are the differences between home-based and snurse-led MDT?

Output: long  intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between home-based and snurse-led MDT?. ### Response: long  intervention.


Instruction: In high risk patients, what is the main difference between Home -Based MDT vs. usual care?

Output: No exploration of uncertainty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In high risk patients, what is the main difference between Home -Based MDT vs. usual care?. ### Response: No exploration of uncertainty.


Instruction: What are the limitations of a Cost -utility analysis?

Output: Potentially serious limitations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the limitations of a Cost -utility analysis?. ### Response: Potentially serious limitations.


Instruction: What is the population of patients >18 years old?

Output: structural cardiac dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population of patients >18 years old?. ### Response: structural cardiac dysfunction.


Instruction: How old are the patients with structural cardiac dysfunction?

Output: >18 years old

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are the patients with structural cardiac dysfunction?. ### Response: >18 years old.


Instruction: What is the population of the patients?

Output: >18 years old

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the population of the patients?. ### Response: >18 years old.


Instruction: How much is the cost saving of the intervention?

Output: £58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much is the cost saving of the intervention?. ### Response: £58.


Instruction: What dominates 1 and 3 (more effective and less costly)?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What dominates 1 and 3 (more effective and less costly)?. ### Response: 2.


Instruction: What is the threshold for Probability intervention 2 cost-effective?

Output: 62%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the threshold for Probability intervention 2 cost-effective?. ### Response: 62%.


Instruction: What is the 2017 VA/SCD GuidelineCirculation. 2018;138:e272–e391 DOI: 10.1161/CIR.0000000000000549 September 25, 2018 e333CLINICAL STATEMENTS AND GUIDELINES7.9.1.4 References that support the recommendations are summarized in what Supplement?

Output: Al-Khatib et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 VA/SCD GuidelineCirculation. 2018;138:e272–e391 DOI: 10.1161/CIR.0000000000000549 September 25, 2018 e333CLINICAL STATEMENTS AND GUIDELINES7.9.1.4 References that support the recommendations are summarized in what Supplement?. ### Response: Al-Khatib et al.


Instruction: What is recommended in asymptomatic patients with an early repolarization pattern on ECG?

Output: observation without treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in asymptomatic patients with an early repolarization pattern on ECG?. ### Response: observation without treatment.


Instruction: What is an ICD recommended if meaningful survival greater than 1 year is expected?

Output: who have a cardiac arrest or sustained  VA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ICD recommended if meaningful survival greater than 1 year is expected?. ### Response: who have a cardiac arrest or sustained  VA.


Instruction: How long is the expected survival?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the expected survival?. ### Response: 1 year.


Instruction: What is not recommended in patients with early repolarization pattern on ECG?

Output: genetic testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended in patients with early repolarization pattern on ECG?. ### Response: genetic testing.


Instruction: What percentage of adults have inferior or lateral leads of at least 0.1 mV?

Output: 5.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of adults have inferior or lateral leads of at least 0.1 mV?. ### Response: 5.8%.


Instruction: What is more common in males?

Output: early repolarization pattern

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more common in males?. ### Response: early repolarization pattern.


Instruction: When was the early repolarization pat-tern lost?

Output: 10-year follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the early repolarization pat-tern lost?. ### Response: 10-year follow-up.


Instruction: How many young males were followed up for 10 years?

Output: >60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many young males were followed up for 10 years?. ### Response: >60%.


Instruction: What are patients determined to have when they have an early repolarization pattern on an ECG?

Output: early repolarization syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients determined to have when they have an early repolarization pattern on an ECG?. ### Response: early repolarization syndrome.


Instruction: What is important to rule out when a patient presents with a revers-ible re-polarization pat-tern?

Output: ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to rule out when a patient presents with a revers-ible re-polarization pat-tern?. ### Response: ischemia.


Instruction: What is important to rule out on an ECG?

Output: ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to rule out on an ECG?. ### Response: ischemia.


Instruction: Patients with early repolarization are more susceptible to the devel-opment of VF during acute cardiac ischemia and/or in the presence of QRS abnormalities?

Output: LV hypertrophy or bundle-branch block

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with early repolarization are more susceptible to the devel-opment of VF during acute cardiac ischemia and/or in the presence of QRS abnormalities?. ### Response: LV hypertrophy or bundle-branch block.


Instruction: What is a term for bundle-branch block?

Output: LV hypertrophy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for bundle-branch block?. ### Response: LV hypertrophy.


Instruction: What percentage of patients have cardiac arrest or VF in the setting of an electrocardiographic pattern of early repolarization?

Output: 40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have cardiac arrest or VF in the setting of an electrocardiographic pattern of early repolarization?. ### Response: 40%.


Instruction: Antiarrhythmic medications have limited efficacy in what?

Output: prevent-ing recurrent VA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antiarrhythmic medications have limited efficacy in what?. ### Response: prevent-ing recurrent VA.


Instruction: What medications have limited efficacy in prevent-ing recurrent VA?

Output: Antiarrhythmic medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What medications have limited efficacy in prevent-ing recurrent VA?. ### Response: Antiarrhythmic medications.


Instruction: Genetic testing has not reliably identified mutations predisposing to what?

Output: early repolarization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Genetic testing has not reliably identified mutations predisposing to what?. ### Response: early repolarization.


Instruction: Online Data Supplement 44.COR LOE RecommendationsI B-NR1. What is recommended in asymptomatic patients with a short QTc interval?

Output: observation without treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Online Data Supplement 44.COR LOE RecommendationsI B-NR1. What is recommended in asymptomatic patients with a short QTc interval?. ### Response: observation without treatment.


Instruction: What is an ICD recommended if meaningful survival greater than 1?

Output: observation without treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ICD recommended if meaningful survival greater than 1?. ### Response: observation without treatment.


Instruction: What is recommended if meaningful survival greater than 1 year is expected?

Output: an ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended if meaningful survival greater than 1 year is expected?. ### Response: an ICD.