Instruction: What have increased cross-clamp and cardiopulmo-nary bypass times?

Output: acute perioperative mortality rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What have increased cross-clamp and cardiopulmo-nary bypass times?. ### Response: acute perioperative mortality rate.


Instruction: When was combined CABG Downloaded from http://ahajournals.org?

Output: April 27, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was combined CABG Downloaded from http://ahajournals.org?. ### Response: April 27, 2023.


Instruction: What measure is identical to the AHA/ASA Ischemic Stroke Performance Measure 11?

Output: Analogous Measures Endorsed by Other Organizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What measure is identical to the AHA/ASA Ischemic Stroke Performance Measure 11?. ### Response: Analogous Measures Endorsed by Other Organizations.


Instruction: What is another measure endorsed or used by NQF?

Output: AHA GWTG–Stroke, CDC PCNASP, and AMA PCPI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another measure endorsed or used by NQF?. ### Response: AHA GWTG–Stroke, CDC PCNASP, and AMA PCPI.


Instruction: What does AHA stand for?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AHA stand for?. ### Response: American Heart Association.


Instruction: What is the acronym for AHA, CDC PCNASP, and AMA PCPI?

Output: GWTG–Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for AHA, CDC PCNASP, and AMA PCPI?. ### Response: GWTG–Stroke.


Instruction: AHA stands for what?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AHA stands for what?. ### Response: American Heart Association.


Instruction: ASA stands for American Stroke Association.

Output: ASA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ASA stands for American Stroke Association.. ### Response: ASA.


Instruction: CDC stands for What?

Output: Centers for Disease Control and Prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CDC stands for What?. ### Response: Centers for Disease Control and Prevention.


Instruction: What is PCNASP?

Output: Paul Coverdell National Acute Stroke program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PCNASP?. ### Response: Paul Coverdell National Acute Stroke program.


Instruction: Who administers a structured bedside swallowing screen?

Output: nursing staff

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who administers a structured bedside swallowing screen?. ### Response: nursing staff.


Instruction: What is a videofluoroscopic swallow evaluation?

Output: Dysphagia screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a videofluoroscopic swallow evaluation?. ### Response: Dysphagia screening.


Instruction: What is another method of swallowing approved by local institutional protocol?

Output: fiberoptic endoscopic evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another method of swallowing approved by local institutional protocol?. ### Response: fiberoptic endoscopic evaluation.


Instruction: When was this publication downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this publication downloaded?. ### Response: April 28, 2023.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 15 of 134 health care delivery systems and those who are in the community receiving care from community-based clinicians?

Output: It includes Veterans as well as deployed and non -deployed active duty Service, Guard, and Reserve Members and their dependents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 15 of 134 health care delivery systems and those who are in the community receiving care from community-based clinicians?. ### Response: It includes Veterans as well as deployed and non -deployed active duty Service, Guard, and Reserve Members and their dependents.


Instruction: What includes Veterans as well as deployed and non deployed?

Output: VA/DoD Clinical Practice Guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What includes Veterans as well as deployed and non deployed?. ### Response: VA/DoD Clinical Practice Guideline.


Instruction: Who is included in the 2020 edition of the VA/DoD HTN Clinical Practice Guideline?

Output: Veterans as well as deployed and non -deployed active duty Service, Guard, and Reserve Members and their dependents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is included in the 2020 edition of the VA/DoD HTN Clinical Practice Guideline?. ### Response: Veterans as well as deployed and non -deployed active duty Service, Guard, and Reserve Members and their dependents.


Instruction: What is the third update to the original CPG?

Output: VA/DoD HTN  CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the third update to the original CPG?. ### Response: VA/DoD HTN  CPG.


Instruction: What provides practice recommendations for the care of individuals with HTN and guidance for treatment?

Output: VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting  March 2020  Page 15 of 134 health care delivery systems and those who are in the community receiving care from community -based clinicians. It includes Veterans as well as deployed and non -deployed active duty Service, Guard, and Reserve Members and their dependents.  E. Highlighted Features  of this Clinical Practice Guideline  The 2020 edition of the VA/DoD HTN  CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides practice recommendations for the care of individuals with HTN and guidance for treatment?. ### Response: VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting  March 2020  Page 15 of 134 health care delivery systems and those who are in the community receiving care from community -based clinicians. It includes Veterans as well as deployed and non -deployed active duty Service, Guard, and Reserve Members and their dependents.  E. Highlighted Features  of this Clinical Practice Guideline  The 2020 edition of the VA/DoD HTN  CPG.


Instruction: What did the framework for recommendations in this CPG consider beyond the strength of the evidence?

Output: balancing desired outcomes with potential harms of the intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the framework for recommendations in this CPG consider beyond the strength of the evidence?. ### Response: balancing desired outcomes with potential harms of the intervention.


Instruction: What was the potential for variation in?

Output: patient values and preferences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the potential for variation in?. ### Response: patient values and preferences.


Instruction: What was also taken into consideration?

Output: Applicability of the evidence to VA/DoD populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was also taken into consideration?. ### Response: Applicability of the evidence to VA/DoD populations.


Instruction: What algorithm accompanies the guideline to provide an overview of the recommendations?

Output: An algorithm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What algorithm accompanies the guideline to provide an overview of the recommendations?. ### Response: An algorithm.


Instruction: What do VA/DoD CPGs encourage patients to do?

Output: focus on shared decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do VA/DoD CPGs encourage patients to do?. ### Response: focus on shared decision making.


Instruction: What is the purpose of the guideline?

Output: provides practice recommendations for the care of individuals with HTN as well as guidance for treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of the guideline?. ### Response: provides practice recommendations for the care of individuals with HTN as well as guidance for treatment.


Instruction: What VA/DoD CPGs encourage providers to use a PCC approach?

Output: Patient -centered Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What VA/DoD CPGs encourage providers to use a PCC approach?. ### Response: Patient -centered Care.


Instruction: What should all patients in the healthcare system be able to access?

Output: evidence -based care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all patients in the healthcare system be able to access?. ### Response: evidence -based care.


Instruction: What type of care is appropriate to a patient's specific needs or condition?

Output: evidence -based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care is appropriate to a patient's specific needs or condition?. ### Response: evidence -based.


Instruction: When properly executed, what may decrease patient anxiety?

Output: PCC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When properly executed, what may decrease patient anxiety?. ### Response: PCC.


Instruction: What conveys openness and supports disclosure of current and future concerns?

Output: Improved patient -clinician co mmunication and a PCC approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What conveys openness and supports disclosure of current and future concerns?. ### Response: Improved patient -clinician co mmunication and a PCC approach.


Instruction: What does the PCC approach include?

Output: individualized based on patient needs, characteristics, and preferences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the PCC approach include?. ### Response: individualized based on patient needs, characteristics, and preferences.


Instruction: What should providers ask each patient about?

Output: any concerns he or she has or barriers to high quality care he or she has experienc ed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should providers ask each patient about?. ### Response: any concerns he or she has or barriers to high quality care he or she has experienc ed.


Instruction: Who encourages shared decision making?

Output: clinicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who encourages shared decision making?. ### Response: clinicians.


Instruction: What does SDM stand for?

Output: shared decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SDM stand for?. ### Response: shared decision making.


Instruction: What is the name of the report that introduced the SDM model?

Output: Crossing the Quality Chasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the report that introduced the SDM model?. ### Response: Crossing the Quality Chasm.


Instruction: When was Crossing the Quality Chasm published?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Crossing the Quality Chasm published?. ### Response: 2001.


Instruction: When was the Medicine [N AM]] report released?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Medicine [N AM]] report released?. ### Response: 2001.


Instruction: What do patients with HTN need to be able to do?

Output: make informed decisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients with HTN need to be able to do?. ### Response: make informed decisions.


Instruction: What must a clinician be adept at presenting to their patients regarding treatments, expected outcomes, and informed decisions?

Output: information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must a clinician be adept at presenting to their patients regarding treatments, expected outcomes, and informed decisions?. ### Response: information.


Instruction: What is unclear orconflicting?

Output: evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unclear orconflicting?. ### Response: evidence.


Instruction: What is not determined because ofnoevidence,insuffi-cient,unclearevidence andthecommitteethoughtnorecommendationshouldbe made?

Output: Balanceofbenefitsandharms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not determined because ofnoevidence,insuffi-cient,unclearevidence andthecommitteethoughtnorecommendationshouldbe made?. ### Response: Balanceofbenefitsandharms.


Instruction: Who developed the system used in this guideline?

Output: NationalHeart,Lung,andBloodInstitute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed the system used in this guideline?. ### Response: NationalHeart,Lung,andBloodInstitute.


Instruction: What is the most heavily investigated potential mecha-nistic link between migraine and stroke?

Output: association of migraine and PFO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most heavily investigated potential mecha-nistic link between migraine and stroke?. ### Response: association of migraine and PFO.


Instruction: What is more common in young patients with cryptogenic stroke and those with migraine?

Output: PFOs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more common in young patients with cryptogenic stroke and those with migraine?. ### Response: PFOs.


Instruction: What type of stroke is particularly common in migraine patients?

Output: ischemic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stroke is particularly common in migraine patients?. ### Response: ischemic.


Instruction: What is the name of the randomized, double-blind, sham-controlled trial that showed no benefit of the MIST trial?

Output: Migraine Intervention with STARFlex Technology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, double-blind, sham-controlled trial that showed no benefit of the MIST trial?. ### Response: Migraine Intervention with STARFlex Technology.


Instruction: What was the primary outcome of the PFO closure trial?

Output: 3 of 74

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary outcome of the PFO closure trial?. ### Response: 3 of 74.


Instruction: How many of the 74 participants in the trial had migraine headaches?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the 74 participants in the trial had migraine headaches?. ### Response: 3.


Instruction: What was not the primary prevention of stroke that the trial did not evaluate?

Output: migraines with aura

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not the primary prevention of stroke that the trial did not evaluate?. ### Response: migraines with aura.


Instruction: What was not designed to evaluate the primary prevention of stroke in patients with migraines with aura?

Output: The Migraine Intervention with STARFlex Technology (MIST) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not designed to evaluate the primary prevention of stroke in patients with migraines with aura?. ### Response: The Migraine Intervention with STARFlex Technology (MIST) trial.


Instruction: Recent studies have found a lack of association between migraine and PFO in a large population-based study among elderly indi-viduals?

Output: 612

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent studies have found a lack of association between migraine and PFO in a large population-based study among elderly indi-viduals?. ### Response: 612.


Instruction: What was the RR of aspirin in patients with migraine?

Output: 0.76

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of aspirin in patients with migraine?. ### Response: 0.76.


Instruction: What is the 95% CI of ischemic stroke?

Output: 0.63–0.93

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% CI of ischemic stroke?. ### Response: 0.63–0.93.


Instruction: In what study was there some doubt about PFO having a causal role in migraines?

Output: meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what study was there some doubt about PFO having a causal role in migraines?. ### Response: meta-analysis.


Instruction: What was the pro-tective effect of aspirin on ischemic stroke similar among women with or without migraines?

Output: In subgroup analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the pro-tective effect of aspirin on ischemic stroke similar among women with or without migraines?. ### Response: In subgroup analyses.


Instruction: Women with migraine with aura had an increased risk of MI (RR, 3.72; 95% CI, 1.39–9.95)?

Output: 615

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Women with migraine with aura had an increased risk of MI (RR, 3.72; 95% CI, 1.39–9.95)?. ### Response: 615.


Instruction: What is the risk of MI for women with history of smoking or hypertension?

Output: 1.39–9.95

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of MI for women with history of smoking or hypertension?. ### Response: 1.39–9.95.


Instruction: Why is the clinical significance of this increased risk for this subgroup unclear?

Output: small numbers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the clinical significance of this increased risk for this subgroup unclear?. ### Response: small numbers.


Instruction: What is migraine associated with in women 55?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is migraine associated with in women 55?. ### Response: stroke.


Instruction: What appears to be associated with stroke in women 55 years of age?

Output: migraine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What appears to be associated with stroke in women 55 years of age?. ### Response: migraine.


Instruction: What is the mechanism linking these 2 conditions unclear?

Output: PFO has a causal role in migraines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mechanism linking these 2 conditions unclear?. ### Response: PFO has a causal role in migraines.


Instruction: The stroke risk of migraine in men seems to be less estab-lished.

Output: Randomized trial evidence that migraine prophylaxis decreases stroke risk is lacking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The stroke risk of migraine in men seems to be less estab-lished.. ### Response: Randomized trial evidence that migraine prophylaxis decreases stroke risk is lacking.


Instruction: What does migraine prophylaxis decrease?

Output: stroke risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does migraine prophylaxis decrease?. ### Response: stroke risk.


Instruction: What is lacking in patients with migraine?

Output: No proven primary prevention strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lacking in patients with migraine?. ### Response: No proven primary prevention strategy.


Instruction: What is the significance of deep white matter lesions and other infarct-like lesions seen on MRI?

Output: remains unclear

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the significance of deep white matter lesions and other infarct-like lesions seen on MRI?. ### Response: remains unclear.


Instruction: There is no proven primary prevention strategy for patients with what?

Output: migraine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no proven primary prevention strategy for patients with what?. ### Response: migraine.


Instruction: What type of studies have shown no benefit in migraine?

Output: well-controlled

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of studies have shown no benefit in migraine?. ### Response: well-controlled.


Instruction: What should be strongly recommended in women with migraine headaches with aura (Class I); Level of Evidence B?

Output: Smoking cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be strongly recommended in women with migraine headaches with aura (Class I); Level of Evidence B?. ### Response: Smoking cessation.


Instruction: OCs, especially those containing estrogen, might be considered in women with active migraine headaches with what?

Output: aura

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: OCs, especially those containing estrogen, might be considered in women with active migraine headaches with what?. ### Response: aura.


Instruction: What are ARBs indicated during hospitalization and at discharge for STEMI patients who are intolerant of ACE inhibitors and have an ejection fraction 0.40 (Class I; Level of Evidence A)?

Output: 169

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ARBs indicated during hospitalization and at discharge for STEMI patients who are intolerant of ACE inhibitors and have an ejection fraction 0.40 (Class I; Level of Evidence A)?. ### Response: 169.


Instruction: What has been used for the treatment of advanced or persistent HF in the convalescent or chronic phase after STEMI?

Output: ACE inhibitors and ARBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been used for the treatment of advanced or persistent HF in the convalescent or chronic phase after STEMI?. ### Response: ACE inhibitors and ARBs.


Instruction: What study failed to show additive benefit but with a substantial benefit?

Output: ONTARGET Study90

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study failed to show additive benefit but with a substantial benefit?. ### Response: ONTARGET Study90.


Instruction: What study failed to show additive benefit but with a substantial increase in side effects?

Output: ONTARGET Study90

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study failed to show additive benefit but with a substantial increase in side effects?. ### Response: ONTARGET Study90.


Instruction: What was not recommended?

Output: ONTARGET Study90

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not recommended?. ### Response: ONTARGET Study90.


Instruction: In the V ALUE trial, what was there no difference in cardiac mortality and morbidity in patients with hypertension and high risk of cardiovascular events?

Output: 107

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the V ALUE trial, what was there no difference in cardiac mortality and morbidity in patients with hypertension and high risk of cardiovascular events?. ### Response: 107.


Instruction: What was the BP-lowering effect of amlodipine greater than that of valsartan?

Output: greater

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the BP-lowering effect of amlodipine greater than that of valsartan?. ### Response: greater.


Instruction: What was no more effective than captopril in patients at high risk for cardiovascular events after MI?

Output: valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was no more effective than captopril in patients at high risk for cardiovascular events after MI?. ### Response: valsartan.


Instruction: Who was at high risk for cardiovascular events after MI?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was at high risk for cardiovascular events after MI?. ### Response: patients.


Instruction: What reduces car -diovascular events?

Output: Thiazide diuretics and thiazide-like diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduces car -diovascular events?. ### Response: Thiazide diuretics and thiazide-like diuretics.


Instruction: What was the name of the study that included subjects with CAD?

Output: ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that included subjects with CAD?. ### Response: ALLHAT.


Instruction: When was ALLHAT.96 downloaded?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was ALLHAT.96 downloaded?. ### Response: May 3, 2023.


Instruction: How many people participated in a meta-analysis of data from 26 randomised trials?

Output: 170 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people participated in a meta-analysis of data from 26 randomised trials?. ### Response: 170 000.


Instruction: When did the Lancet issue 376:1670–81?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet issue 376:1670–81?. ### Response: 2010.


Instruction: What race did Naito R, Miyauchi K, Daida H have?

Output: Racial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What race did Naito R, Miyauchi K, Daida H have?. ### Response: Racial.


Instruction: What is the evi-dence for the efficacy and safety of statin therapy?

Output: side-effect profile

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the evi-dence for the efficacy and safety of statin therapy?. ### Response: side-effect profile.


Instruction: What is available at: http://tools.acc.org/ldl?

Output: American College of Cardiology. American College of Cardiology LDL-C Manager

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is available at: http://tools.acc.org/ldl?. ### Response: American College of Cardiology. American College of Cardiology LDL-C Manager.


Instruction: What does LDL-C Manager do?

Output: Safety of very low low-density lipoprotein cholesterol levels with alirocumab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LDL-C Manager do?. ### Response: Safety of very low low-density lipoprotein cholesterol levels with alirocumab.


Instruction: When was Ezetimibe added to statin therapy after acute coronary syndromes?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Ezetimibe added to statin therapy after acute coronary syndromes?. ### Response: 2015.


Instruction: What is the acronym for nonstatin therapies?

Output: Nonstatin Therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for nonstatin therapies?. ### Response: Nonstatin Therapies.


Instruction: What is ezetimibe and statin therapy used for?

Output: randomized clinical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ezetimibe and statin therapy used for?. ### Response: randomized clinical trials.


Instruction: What is the risk of neu-rocognitive outcomes with proprotein convertase?

Output: Increased risk of adverse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of neu-rocognitive outcomes with proprotein convertase?. ### Response: Increased risk of adverse.


Instruction: What is the name of the proprotein convertase subtilisin-kexin type 9 inhibitor?

Output: Ezetimibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the proprotein convertase subtilisin-kexin type 9 inhibitor?. ### Response: Ezetimibe.


Instruction: What is alirocumab used for?

Output: Safety of very low low-density lipoprotein cholesterol levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is alirocumab used for?. ### Response: Safety of very low low-density lipoprotein cholesterol levels.


Instruction: What is evolocumab and clini-cal outcomes in patients with cardiovascular disease?

Output: reducing lipids and cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evolocumab and clini-cal outcomes in patients with cardiovascular disease?. ### Response: reducing lipids and cardiovascular events.


Instruction: What is the name of the randomized trial?

Output: ODYSSEY COMBO II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial?. ### Response: ODYSSEY COMBO II.


Instruction: What is evolocumab used for in a ran-domized trial?

Output: Cognitive function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evolocumab used for in a ran-domized trial?. ### Response: Cognitive function.


Instruction: What is Ezetimibe added to Statin Therapy after Acute Coronary Syndromes?

Output: S3.2.2-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Ezetimibe added to Statin Therapy after Acute Coronary Syndromes?. ### Response: S3.2.2-2.


Instruction: What is ali-rocumab used for in high cardiovascular risk patients?

Output: Efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ali-rocumab used for in high cardiovascular risk patients?. ### Response: Efficacy and safety.


Instruction: What is the name of the part 1 of a report on the National lipid association?

Output: rec-ommendations for patient-centered management of dyslipidemia: part 1–full report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the part 1 of a report on the National lipid association?. ### Response: rec-ommendations for patient-centered management of dyslipidemia: part 1–full report.


Instruction: What is ali-rocumab used for in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia?

Output: Efficacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ali-rocumab used for in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia?. ### Response: Efficacy and safety.


Instruction: What is the name of the randomized controlled trial that evaluated the efficacy and safety of statins?

Output: ODYSSEY COMBO II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial that evaluated the efficacy and safety of statins?. ### Response: ODYSSEY COMBO II.


Instruction: How does evolocumab reduce lipids and cholesterol?

Output: Safety of very low low-density lipoprotein cholesterol levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does evolocumab reduce lipids and cholesterol?. ### Response: Safety of very low low-density lipoprotein cholesterol levels.


Instruction: What is evolocumab effective at reducing?

Output: lipids and cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is evolocumab effective at reducing?. ### Response: lipids and cardiovascular events.


Instruction: What is secondary ASCVD Prevention S4.1-1?

Output: High-dose atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is secondary ASCVD Prevention S4.1-1?. ### Response: High-dose atorvastatin.


Instruction: How is atorvastatin used after stroke or transient ischemic attack?

Output: High-dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is atorvastatin used after stroke or transient ischemic attack?. ### Response: High-dose.


Instruction: What year did N Engl J Med issue 355:549-59?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med issue 355:549-59?. ### Response: 2006.


Instruction: What is the name of the study that investigated ischemic attack?

Output: ODYSSEY COMBO II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated ischemic attack?. ### Response: ODYSSEY COMBO II.


Instruction: Powers and al 2019 Guidelines for Management of AIS e3552. Emergency Evaluation and Treatment2.1. Stroke Scales COR LOE New, Revised, or Unchanged1. The use of a stroke severity rating scale, preferably the NIHSS, is recommended.

Output: 75

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Powers and al 2019 Guidelines for Management of AIS e3552. Emergency Evaluation and Treatment2.1. Stroke Scales COR LOE New, Revised, or Unchanged1. The use of a stroke severity rating scale, preferably the NIHSS, is recommended.. ### Response: 75.


Instruction: B-NRRecommendation reworded for clarity from 2013 AIS Guidelines.

Output: stroke severity rating scale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: B-NRRecommendation reworded for clarity from 2013 AIS Guidelines.. ### Response: stroke severity rating scale.


Instruction: COR unchanged.

Output: LOE amended to conform with ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: COR unchanged.. ### Response: LOE amended to conform with ACC/AHA 2015 Recommendation Classification System.


Instruction: LOE amended to conform with what?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LOE amended to conform with what?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: What can be performed quickly, have demonstrated utility, and be administered by a broad spectrum of healthcare providers with accuracy and reliability?

Output: Table 4)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be performed quickly, have demonstrated utility, and be administered by a broad spectrum of healthcare providers with accuracy and reliability?. ### Response: Table 4).


Instruction: Use of a standardized scale quantifies the degree of neurological deficit, facilitates communication, helps identify patients for what?

Output: fibrinolytic or mechanical intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Use of a standardized scale quantifies the degree of neurological deficit, facilitates communication, helps identify patients for what?. ### Response: fibrinolytic or mechanical intervention.


Instruction: What type of intervention allows objective measurement of changing clinical status and identifies those at higher risk for complications such as intracerebral hemorrhage?

Output: fibrinolytic or mechanical intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention allows objective measurement of changing clinical status and identifies those at higher risk for complications such as intracerebral hemorrhage?. ### Response: fibrinolytic or mechanical intervention.


Instruction: What is a Level of consciousness0?

Output: —Alert

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Level of consciousness0?. ### Response: —Alert.


Instruction: What is an alert 1?

Output: 1—Drowsy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an alert 1?. ### Response: 1—Drowsy.


Instruction: What is the difference between partial and complete gaze palsy?

Output: Visual fields 0—No visual field defect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between partial and complete gaze palsy?. ### Response: Visual fields 0—No visual field defect.


Instruction: What are the differences between partial hemianopia 2 and complete eyepalsy 3?

Output: Visual fields 0—No visual field defect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between partial hemianopia 2 and complete eyepalsy 3?. ### Response: Visual fields 0—No visual field defect.


Instruction: Before 10 sb. Right 2—Falls before what s 3—No effort against gravity 4—No movement6 Motor function (leg) 0—No drift a. Left 1—Drift before how many seconds?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Before 10 sb. Right 2—Falls before what s 3—No effort against gravity 4—No movement6 Motor function (leg) 0—No drift a. Left 1—Drift before how many seconds?. ### Response: 10.


Instruction: How many limbs are affected by ataxia?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many limbs are affected by ataxia?. ### Response: 2.


Instruction: What type of loss is present in 1 limb?

Output: Ataxia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of loss is present in 1 limb?. ### Response: Ataxia.


Instruction: In what limb is there no loss of sensory information?

Output: Sensory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what limb is there no loss of sensory information?. ### Response: Sensory.


Instruction: Inattention0—Absent 1—Mild loss (1 sensory modality lost) 2—Severe loss (2 modalities lost)Adapted from Lyden et al.74 Copyright  1994, American Heart Association, Inc.Table 4. ContinuedTested Item Title Responses and ScoresDownloaded by on what date?

Output: Extinction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inattention0—Absent 1—Mild loss (1 sensory modality lost) 2—Severe loss (2 modalities lost)Adapted from Lyden et al.74 Copyright  1994, American Heart Association, Inc.Table 4. ContinuedTested Item Title Responses and ScoresDownloaded by on what date?. ### Response: Extinction.


Instruction: Chapter 7: Blood pressure management in elderly people with CKD NDKidney International Supplements (2012) 2,377-381. doi:10.1038/kisup.2012.57INTRODUCTIONThis chapter specifically addresses the BP management of older patients with what?

Output: CKD that is non-dialysis-dependent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chapter 7: Blood pressure management in elderly people with CKD NDKidney International Supplements (2012) 2,377-381. doi:10.1038/kisup.2012.57INTRODUCTIONThis chapter specifically addresses the BP management of older patients with what?. ### Response: CKD that is non-dialysis-dependent.


Instruction: What is the term used for personsZ65 years of age?

Output: elderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term used for personsZ65 years of age?. ### Response: elderly.


Instruction: What term is reserved for persons 480 years old?

Output: very elderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What term is reserved for persons 480 years old?. ### Response: very elderly.


Instruction: How is chronological age used?

Output: as a surrogate for biological age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is chronological age used?. ### Response: as a surrogate for biological age.


Instruction: What is used as a surrogate for biological age?

Output: chronological age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used as a surrogate for biological age?. ### Response: chronological age.


Instruction: Who comprise the most rapidly growing proportion of the population in most parts of the world?

Output: The elderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who comprise the most rapidly growing proportion of the population in most parts of the world?. ### Response: The elderly.


Instruction: From 30 to 40 years of age, the GFR generally (but not invariably)declines.

Output: 357

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: From 30 to 40 years of age, the GFR generally (but not invariably)declines.. ### Response: 357.


Instruction: What is the most rapidly growing population of CKD patients?

Output: theelderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most rapidly growing population of CKD patients?. ### Response: theelderly.


Instruction: What is a common problem in the older person?

Output: tubular and endocrinedysfunction in the kidney

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common problem in the older person?. ### Response: tubular and endocrinedysfunction in the kidney.


Instruction: How much of the population have a reduced GFR?

Output: a large proportion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the population have a reduced GFR?. ### Response: a large proportion.


Instruction: What percentage of subjects 470 years had a GFR of o60 ml/min/1.73 m2?

Output: 37.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of subjects 470 years had a GFR of o60 ml/min/1.73 m2?. ### Response: 37.8%.


Instruction: What was the rate of CKD in the 1988-1994 data?

Output: 27.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the rate of CKD in the 1988-1994 data?. ### Response: 27.8%.


Instruction: What percentage of U.S.veterans aged 485 years fulfilled the definition for CKDD?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of U.S.veterans aged 485 years fulfilled the definition for CKDD?. ### Response: 50%.


Instruction: In what countries has a highprevalence of the disease been found in older populations?

Output: China,363Australia,364and Japan,365

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what countries has a highprevalence of the disease been found in older populations?. ### Response: China,363Australia,364and Japan,365.


Instruction: What is the fastest growing population requiring dialysis?

Output: theelderly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the fastest growing population requiring dialysis?. ### Response: theelderly.


Instruction: How old are the majority of patients receiving renal replacement therapy in the United Kingdom?

Output: 465 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are the majority of patients receiving renal replacement therapy in the United Kingdom?. ### Response: 465 years of age.


Instruction: How do you tailor BP treatment regimens in elderly patients with CKD ND?

Output: non-dialysis-dependent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do you tailor BP treatment regimens in elderly patients with CKD ND?. ### Response: non-dialysis-dependent.


Instruction: What are some of the adverse events related to BP therapy?

Output: electrolyte dis-orders, acute deterioration in kidney function,orthostatic hypotension and drug side effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the adverse events related to BP therapy?. ### Response: electrolyte dis-orders, acute deterioration in kidney function,orthostatic hypotension and drug side effects.


Instruction: What was the relationship between BP and CKD in the elderly in the United States?

Output: J-shaped

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the relationship between BP and CKD in the elderly in the United States?. ### Response: J-shaped.


Instruction: When did NHANES III take place?

Output: 1988– 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did NHANES III take place?. ### Response: 1988– 1994.


Instruction: How old were the subjects treated or not treated for high BP?

Output: Z60 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old were the subjects treated or not treated for high BP?. ### Response: Z60 years of age.


Instruction: What was the aJ-shaped relationship between BP and CKD prevalence?

Output: highly variable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the aJ-shaped relationship between BP and CKD prevalence?. ### Response: highly variable.


Instruction: What did people with a systolic BP of 120 to 159 mm Hg have the lowest?

Output: CKD prevalence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did people with a systolic BP of 120 to 159 mm Hg have the lowest?. ### Response: CKD prevalence.


Instruction: What has little evidence of value in low-risk patients?

Output: SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has little evidence of value in low-risk patients?. ### Response: SCD.


Instruction: What has not had a significant effect on QoL in the overall population of patients enrolled in RCTs?

Output: QUALITY OF LIFEICD implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not had a significant effect on QoL in the overall population of patients enrolled in RCTs?. ### Response: QUALITY OF LIFEICD implantation.


Instruction: The subset of patients who receive inap-propriate ICD shocks have what?

Output: worse QoL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The subset of patients who receive inap-propriate ICD shocks have what?. ### Response: worse QoL.


Instruction: What type of patients have worse QoL than patients who have an ICD but haven't had inappropriate shocks?

Output: the subset of patients who receive inap-propriate ICD shocks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients have worse QoL than patients who have an ICD but haven't had inappropriate shocks?. ### Response: the subset of patients who receive inap-propriate ICD shocks.


Instruction: What is a ICD designed to prevent rather than to reduce symptoms?

Output: SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a ICD designed to prevent rather than to reduce symptoms?. ### Response: SCD.


Instruction: What may have negative effects in some patients due to device complications?

Output: ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have negative effects in some patients due to device complications?. ### Response: ICD.


Instruction: What can have indirect, positive effects on some patients?

Output: reassurance of having a protective device in place

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can have indirect, positive effects on some patients?. ### Response: reassurance of having a protective device in place.


Instruction: How is the cost-effectiveness of ICD calculated?

Output: by years of life added

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the cost-effectiveness of ICD calculated?. ### Response: by years of life added.


Instruction: What is ICD by years of life added?

Output: Incremental cost-effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ICD by years of life added?. ### Response: Incremental cost-effectiveness.


Instruction: What is the Incremental cost-effectiveness ratio?

Output: $50 000/QALYs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Incremental cost-effectiveness ratio?. ### Response: $50 000/QALYs.


Instruction: How much does ICD cost?

Output: $50 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much does ICD cost?. ### Response: $50 000.


Instruction: Where can ICD be downloaded?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can ICD be downloaded?. ### Response: http://ahajournals.org.


Instruction: What was the adjusted OR for death within 30 days for subjects receiv-ing insulin?

Output: 1.50

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the adjusted OR for death within 30 days for subjects receiv-ing insulin?. ### Response: 1.50.


Instruction: What were the risks for other compli-cations?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the risks for other compli-cations?. ### Response: higher.


Instruction: The poorer short-term outcome in patients with diabetes is only partly explained by what?

Output: greater frequency of other comorbid conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The poorer short-term outcome in patients with diabetes is only partly explained by what?. ### Response: greater frequency of other comorbid conditions.


Instruction: What are some other comorbid conditions?

Output: obesity, hypertension, renal insufficiency, PAD, and cerebro-vascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some other comorbid conditions?. ### Response: obesity, hypertension, renal insufficiency, PAD, and cerebro-vascular disease.


Instruction: What is the reduced long-term survival rate afterCABG in patients with diabetes?

Output: more rapid progression of atherosclerosis, a lower long-term patency rate of SVGs,1173 and a greater burden ofcomorbid conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reduced long-term survival rate afterCABG in patients with diabetes?. ### Response: more rapid progression of atherosclerosis, a lower long-term patency rate of SVGs,1173 and a greater burden ofcomorbid conditions.


Instruction: What is a greater burden ofcomorbid conditions?

Output: a lower long-term patency rate of SVGs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a greater burden ofcomorbid conditions?. ### Response: a lower long-term patency rate of SVGs.


Instruction: What is better after CABG when an IMA is used as a conduit than when CABG is performed with only SVGs?

Output: long-term outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is better after CABG when an IMA is used as a conduit than when CABG is performed with only SVGs?. ### Response: long-term outcome.


Instruction: What did the BARI trial show?

Output: patients with diabetes who underwent CABG with 1arterial conduit had improved survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the BARI trial show?. ### Response: patients with diabetes who underwent CABG with 1arterial conduit had improved survival.


Instruction: What did CABG with 1arterial conduit have in patients with diabetes compared with those who underwent PCI?

Output: improved survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did CABG with 1arterial conduit have in patients with diabetes compared with those who underwent PCI?. ### Response: improved survival.


Instruction: How many RCTs did a meta-analysis of?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs did a meta-analysis of?. ### Response: 10.


Instruction: How many RCTs compared CABG with balloon angioplasty or BMS implantation?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs compared CABG with balloon angioplasty or BMS implantation?. ### Response: 10.


Instruction: What was significantly lower inpatients with diabetes undergoing CABG?

Output: mortality rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was significantly lower inpatients with diabetes undergoing CABG?. ### Response: mortality rate.


Instruction: How much information is available about CABGversus PCIwith DES in patients with diabetes mellitus?

Output: Little

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much information is available about CABGversus PCIwith DES in patients with diabetes mellitus?. ### Response: Little.


Instruction: What is the name of the first RCT comparing CABG and PCI in a population consisting entirely of subjects with diabetes?

Output: CARDia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the first RCT comparing CABG and PCI in a population consisting entirely of subjects with diabetes?. ### Response: CARDia.


Instruction: How many of the 1,800 subjects enrolled in the SYNTAX trial achieved similar outcomes?

Output: 475

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the 1,800 subjects enrolled in the SYNTAX trial achieved similar outcomes?. ### Response: 475.


Instruction: What percentage of PCI patients used DES?

Output: 69%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of PCI patients used DES?. ### Response: 69%.


Instruction: How many of the 1,800 subjects enrolled in the SYNTAX trial had medically treated diabe-tes?

Output: 452

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the 1,800 subjects enrolled in the SYNTAX trial had medically treated diabe-tes?. ### Response: 452.


Instruction: How many patients had a similareffect on survival, MI, and the composite endpoint of death,MI, or stroke at 1-year follow-up?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had a similareffect on survival, MI, and the composite endpoint of death,MI, or stroke at 1-year follow-up?. ### Response: 2.


Instruction: What type of patient had a higher rate of repeat revascularization after PCI versus 6.4%after CABG?

Output: abetes randomly assigned to receive PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patient had a higher rate of repeat revascularization after PCI versus 6.4%after CABG?. ### Response: abetes randomly assigned to receive PCI.


Instruction: What was the mortality rate with PCI in the SYNTAX cohort?

Output: 13.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mortality rate with PCI in the SYNTAX cohort?. ### Response: 13.5%.


Instruction: What was the rate with PCI?

Output: 13.5% versus 4.1%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the rate with PCI?. ### Response: 13.5% versus 4.1%;.


Instruction: What is the P/H110050.04?

Output: higher mortality rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the P/H110050.04?. ### Response: higher mortality rate.


Instruction: The FREEDOM trial compares CABG and PCI with what?

Output: DES

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The FREEDOM trial compares CABG and PCI with what?. ### Response: DES.


Instruction: How many patients with diabetes and multivesselCAD were compared?

Output: 1900

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with diabetes and multivesselCAD were compared?. ### Response: 1900.


Instruction: What is the preferred therapy for these patients?

Output: IMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preferred therapy for these patients?. ### Response: IMA.


Instruction: How many comparisons were made between CABG and contemporary medical?

Output: 1175Few

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many comparisons were made between CABG and contemporary medical?. ### Response: 1175Few.


Instruction: What percentage of patients have AF immediately after CABG?

Output: 20% to 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have AF immediately after CABG?. ### Response: 20% to 50%.


Instruction: What is AF associated with?

Output: increased risk of morbidity (particularly dis-abling embolic events) and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is AF associated with?. ### Response: increased risk of morbidity (particularly dis-abling embolic events) and mortality.


Instruction: How many consecutive subjects underwent CABG in a prospective study?

Output: 1878

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many consecutive subjects underwent CABG in a prospective study?. ### Response: 1878.


Instruction: How much increased was the risk of disabling embolic stroke after CABG?

Output: 4-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increased was the risk of disabling embolic stroke after CABG?. ### Response: 4-fold.


Instruction: How much higher was the chance of cardiac-related death after AF?

Output: 3-fold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was the chance of cardiac-related death after AF?. ### Response: 3-fold.


Instruction: What is an example of an increase in postoperative AF in the presence of advanced patient age and male sex?

Output: PAD, chroniclung disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an increase in postoperative AF in the presence of advanced patient age and male sex?. ### Response: PAD, chroniclung disease.


Instruction: Disease, left atrialenlargement, previous cardiac surgery, pericarditis, and elevated postoperativeadrenergic tone are examples of what?

Output: postoperative AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Disease, left atrialenlargement, previous cardiac surgery, pericarditis, and elevated postoperativeadrenergic tone are examples of what?. ### Response: postoperative AF.


Instruction: Postoperative AF almost always occurs within how many dayspostoperatively?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Postoperative AF almost always occurs within how many dayspostoperatively?. ### Response: 5.


Instruction: On what day does AF peak?

Output: second postop-erative day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what day does AF peak?. ### Response: second postop-erative day.


Instruction: How many trials have assessed the efficacy of AF?

Output: several RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many trials have assessed the efficacy of AF?. ### Response: several RCTs.


Instruction: What are the most effective at reducing post-CABG AF?

Output: Preoperative and postoperative betablockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the most effective at reducing post-CABG AF?. ### Response: Preoperative and postoperative betablockers.


Instruction: What are some antiarrhythmicagents that have been evaluated for their effectiveness?

Output: blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some antiarrhythmicagents that have been evaluated for their effectiveness?. ### Response: blockers.


Instruction: How are preoperative and postoperative betablockers used?

Output: reducing its incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are preoperative and postoperative betablockers used?. ### Response: reducing its incidence.


Instruction: How long after surgery does post-CABG AF usually resolve?

Output: 6 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after surgery does post-CABG AF usually resolve?. ### Response: 6 weeks.


Instruction: What is the preferred management strategy of post-CABG AF?

Output: control of the ventricular rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preferred management strategy of post-CABG AF?. ### Response: control of the ventricular rate.


Instruction: What is controlled with betablockers in anticipation of spontaneous reversion to sinusrhythm within weeks?

Output: ventricular rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is controlled with betablockers in anticipation of spontaneous reversion to sinusrhythm within weeks?. ### Response: ventricular rate.


Instruction: What is anticoagulation with heparin and warfarin used for?

Output: if the patient isconsidered to be at risk for a thromboembolic event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is anticoagulation with heparin and warfarin used for?. ### Response: if the patient isconsidered to be at risk for a thromboembolic event.


Instruction: What 2011 ACCF/AHA/HRS guidelines for the Managementof Patients with Atrial Fibrillation?

Output: 6085.2.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What 2011 ACCF/AHA/HRS guidelines for the Managementof Patients with Atrial Fibrillation?. ### Response: 6085.2.6.


Instruction: What should be used to limit the number of transfusions?

Output: ategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used to limit the number of transfusions?. ### Response: ategy.


Instruction: What is useful intraoperatively and postoperatively in patients undergoing on-pumpCABG?

Output: Lysine analogues

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful intraoperatively and postoperatively in patients undergoing on-pumpCABG?. ### Response: Lysine analogues.


Instruction: How long should clopidogrel and ticagrelor be with-held in patients with elective CABG?

Output: at least 5 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should clopidogrel and ticagrelor be with-held in patients with elective CABG?. ### Response: at least 5 days.


Instruction: What should be used to limit the number of trans-fusions?

Output: ategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used to limit the number of trans-fusions?. ### Response: ategy.


Instruction: • Discuss adherence (see recommendation 1.4.40).

Output: adher ence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: • Discuss adherence (see recommendation 1.4.40).. ### Response: adher ence.


Instruction: For people with confirmed r esistant h yper tension, consider adding what as st ep 4 treatment or seeking specialist advice?

Output: a fourth antih yper tensiv e drug

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For people with confirmed r esistant h yper tension, consider adding what as st ep 4 treatment or seeking specialist advice?. ### Response: a fourth antih yper tensiv e drug.


Instruction: Follow the MHRA saf ety advice on what?

Output: A CE inhibit ors and angiot ensin II recept or antagonist s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Follow the MHRA saf ety advice on what?. ### Response: A CE inhibit ors and angiot ensin II recept or antagonist s.


Instruction: What is the MHRA's advice on A CE inhibit ors and angiot ensin II recept or antagonist?

Output: not f or use in pr egnancy , how to use f or breastf eeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the MHRA's advice on A CE inhibit ors and angiot ensin II recept or antagonist?. ### Response: not f or use in pr egnancy , how to use f or breastf eeding.


Instruction: How to use f or breastfeeding?

Output: how to use f or breastf eeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How to use f or breastfeeding?. ### Response: how to use f or breastf eeding.


Instruction: What should you consider fur ther diur etic t herap y?

Output: low-dose spir onolact one f

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should you consider fur ther diur etic t herap y?. ### Response: low-dose spir onolact one f.


Instruction: How much potassium le vel does a person need?

Output: 4 .5 mmol/l

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much potassium le vel does a person need?. ### Response: 4 .5 mmol/l.


Instruction: What is a spironolact one f or adult s with resistant h yper tension star ting st ep 4 treatment who has a blood potassium level of 4.5mmol/l or less?

Output: alpha-block er or beta-block er

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a spironolact one f or adult s with resistant h yper tension star ting st ep 4 treatment who has a blood potassium level of 4.5mmol/l or less?. ### Response: alpha-block er or beta-block er.


Instruction: How much mmol/l or less is recommended?

Output: 4 .5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much mmol/l or less is recommended?. ### Response: 4 .5.


Instruction: Who has an increased risk of h yperkalaemia?

Output: people with a reduced estimat ed glomerular filtration rat e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has an increased risk of h yperkalaemia?. ### Response: people with a reduced estimat ed glomerular filtration rat e.


Instruction: What was an off-label use of some pr eparations of spironolact one?

Output: low-dose spir onolact one f or adult s with resistant h yper tension star ting st ep 4 treatment who ha ve a blood potassium le vel of 4 .5 mmol/l or less. Use par ticular caution in people with a reduced estimat ed glomerular filtration rat e because t hey have an increased risk of h yperkalaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was an off-label use of some pr eparations of spironolact one?. ### Response: low-dose spir onolact one f or adult s with resistant h yper tension star ting st ep 4 treatment who ha ve a blood potassium le vel of 4 .5 mmol/l or less. Use par ticular caution in people with a reduced estimat ed glomerular filtration rat e because t hey have an increased risk of h yperkalaemia.


Instruction: What does NICE's inf ormation on pr escribing medicines include?

Output: 1.4.50

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NICE's inf ormation on pr escribing medicines include?. ### Response: 1.4.50.


Instruction: What is used when using fur ther diur etic t herapy for st ep 4 treatment of r esistant hyper tension?

Output: 4  drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used when using fur ther diur etic t herapy for st ep 4 treatment of r esistant hyper tension?. ### Response: 4  drugs.


Instruction: Blood sodium and potassium and r enal function within 1 mont h of star ting tr eatment and as needed t hereafter?

Output: When using fur ther diur etic t herap y for st ep 4 treatment of r esistant hyper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood sodium and potassium and r enal function within 1 mont h of star ting tr eatment and as needed t hereafter?. ### Response: When using fur ther diur etic t herap y for st ep 4 treatment of r esistant hyper tension.


Instruction: What is an alpha-blocker or beta-block er for?

Output: adult s wit h resistant hyper tension star ting st ep 4 treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an alpha-blocker or beta-block er for?. ### Response: adult s wit h resistant hyper tension star ting st ep 4 treatment.


Instruction: Who has a blood potassium le vel of mor e than 4.5 mmol/l?

Output: an alpha-block er or beta-block er

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has a blood potassium le vel of mor e than 4.5 mmol/l?. ### Response: an alpha-block er or beta-block er.


Instruction: What does hyper tension star ting st ep 4 treatment do?

Output: blood potassium le vel of mor e than 4 .5 mmol/l

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does hyper tension star ting st ep 4 treatment do?. ### Response: blood potassium le vel of mor e than 4 .5 mmol/l.


Instruction: How many drugs should you take?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drugs should you take?. ### Response: 4.


Instruction: What is the name of the book that describes hyper tension in adult s?

Output: NG136

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes hyper tension in adult s?. ### Response: NG136.


Instruction: When was the last updat ed?

Output: 18 Mar ch 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed?. ### Response: 18 Mar ch 2022.


Instruction: What was the last updat ed 18 Mar ch 2022Page 22of 51?

Output: Notice of right s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the last updat ed 18 Mar ch 2022Page 22of 51?. ### Response: Notice of right s.


Instruction: What is the ideal goal of reducing dietary sodium?

Output: <1500 mg/d

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ideal goal of reducing dietary sodium?. ### Response: <1500 mg/d.


Instruction: What is a healthy diet?

Output: rich in fruits, vegetables, whole grains, and low-fat dairy products

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a healthy diet?. ### Response: rich in fruits, vegetables, whole grains, and low-fat dairy products.


Instruction: 1500 mg/d, but aim for at least a 1000-mg/d reduction in most adults?

Output: <1500

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1500 mg/d, but aim for at least a 1000-mg/d reduction in most adults?. ### Response: <1500.


Instruction: Enhanced intake of dietary potassiumAim for what?

Output: 3500–5000 mg/d

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Enhanced intake of dietary potassiumAim for what?. ### Response: 3500–5000 mg/d.


Instruction: Aim for 3500–5000 mg per day, preferably by consumption of a diet rich in potassium?

Output: Dietary potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aim for 3500–5000 mg per day, preferably by consumption of a diet rich in potassium?. ### Response: Dietary potassium.


Instruction: Aerobic 90–150 min/wk65%–75% heart rate reserve?

Output: potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aerobic 90–150 min/wk65%–75% heart rate reserve?. ### Response: potassium.


Instruction: mm Hg S4.4-14Physical activity Aerobic 90–150 min/wk65%–75% heart rate reserve-5/8 mm hg -2/4 mm S4.4-19,S4.4-20Dynamic resistance 90-150 min/1wk50%–80% 1 rep maximum6 exercises, 3 sets/exercise, 10 repetitions/set?

Output: 4/5 mm Hg -2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: mm Hg S4.4-14Physical activity Aerobic 90–150 min/wk65%–75% heart rate reserve-5/8 mm hg -2/4 mm S4.4-19,S4.4-20Dynamic resistance 90-150 min/1wk50%–80% 1 rep maximum6 exercises, 3 sets/exercise, 10 repetitions/set?. ### Response: 4/5 mm Hg -2.


Instruction: Isometric resistance 42 min (hand grip), 1 min rest between exercises, 30%–40% maximum voluntary contraction?

Output: Dynamic resistance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Isometric resistance 42 min (hand grip), 1 min rest between exercises, 30%–40% maximum voluntary contraction?. ### Response: Dynamic resistance.


Instruction: What is the maximum voluntary contraction between exercises?

Output: 30%–40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum voluntary contraction between exercises?. ### Response: 30%–40%.


Instruction: How much rest between exercises is required?

Output: 1 min

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much rest between exercises is required?. ### Response: 1 min.


Instruction: What type of alcohol intake can be reduced in individuals who drink alcohol?

Output: Alcohol consumption

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of alcohol intake can be reduced in individuals who drink alcohol?. ### Response: Alcohol consumption.


Instruction: How much alcohol does a standard drink in the United States contain?

Output: 14 g

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much alcohol does a standard drink in the United States contain?. ### Response: 14 g.


Instruction: How many oz of alcohol is typically found in 1 standard drink?

Output: 12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many oz of alcohol is typically found in 1 standard drink?. ### Response: 12.


Instruction: What type of diet is available for adults with normal BP and hypertension?

Output: DASH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet is available for adults with normal BP and hypertension?. ### Response: DASH.


Instruction: What is the typical amount of pure alcohol found in 12 oz of regular beer?

Output: 5% alcohol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the typical amount of pure alcohol found in 12 oz of regular beer?. ### Response: 5% alcohol.


Instruction: How much alcohol is usually found in 5 ounces of wine?

Output: 12%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much alcohol is usually found in 5 ounces of wine?. ### Response: 12%.


Instruction: What does S4.4-64BP indicate?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does S4.4-64BP indicate?. ### Response: blood pressure.


Instruction: What is NHLBI?

Output: National Heart, Lung, and Blood Institute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NHLBI?. ### Response: National Heart, Lung, and Blood Institute.


Instruction: What is SBP?

Output: systolic blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SBP?. ### Response: systolic blood pressure.


Instruction: Who et al. gave permission to reproduce this article?

Output: Whelton

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who et al. gave permission to reproduce this article?. ### Response: Whelton.


Instruction: When was this article originally published?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article originally published?. ### Response: May 1, 2023.


Instruction: What is NICE 2018?

Output: Monitoring  Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: Monitoring  Chronic Heart Failure.


Instruction: What are the Outcomes No of Participants (studies) Follow up Quality of evidence?

Output: Relative effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Outcomes No of Participants (studies) Follow up Quality of evidence?. ### Response: Relative effect.


Instruction: What is the risk difference with NP monitoring (95% CI) 12 months 0.89) All-cause hospitalisation (HR) - Age 75 years 50 (1 study) How long  a study?

Output: Risk with No monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk difference with NP monitoring (95% CI) 12 months 0.89) All-cause hospitalisation (HR) - Age 75 years 50 (1 study) How long  a study?. ### Response: Risk with No monitoring.


Instruction: How long did it take for a study to complete?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for a study to complete?. ### Response: 12 months.


Instruction: Why was the study VERY LOWb,c due to risk of bias?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the study VERY LOWb,c due to risk of bias?. ### Response: imprecision.


Instruction: What was the estimated rate of hospitalisation per 1000?

Output: 699

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the estimated rate of hospitalisation per 1000?. ### Response: 699.


Instruction: How many more hospitalisations per 10 00?

Output: 28

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many more hospitalisations per 10 00?. ### Response: 28.


Instruction: How many more hospitalisations per 1000?

Output: 310

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many more hospitalisations per 1000?. ### Response: 310.


Instruction: What is the HR of all-cause hospitalisation - Age 75 and over 70 (1 study) 12 months  VERYLOWb,c due to risk of bias, imprecision HR 1.66 (0.81 to 3.4) Estimated 699 per 1000 165 more per 1000

Output: VERY LOWb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the HR of all-cause hospitalisation - Age 75 and over 70 (1 study) 12 months  VERYLOWb,c due to risk of bias, imprecision HR 1.66 (0.81 to 3.4) Estimated 699 per 1000 165 more per 1000. ### Response: VERY LOWb.


Instruction: How many more hospitalisations per 1 000?

Output: 118

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many more hospitalisations per 1 000?. ### Response: 118.


Instruction: What is the RR of HF hospitalisation?

Output: Age <75 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the RR of HF hospitalisation?. ### Response: Age <75 years.


Instruction: Why is VERY L OWc,e due to indirectness, imprecision?

Output: RR 0.82  (0.49 to 1.37

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is VERY L OWc,e due to indirectness, imprecision?. ### Response: RR 0.82  (0.49 to 1.37.


Instruction: Why is a LOWc,e due to indirectness?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is a LOWc,e due to indirectness?. ### Response: imprecision.


Instruction: How many studies did MODERATEe have?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did MODERATEe have?. ### Response: 1.


Instruction: What was the imprecision rate?

Output: HR 1.08

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the imprecision rate?. ### Response: HR 1.08.


Instruction: How long is a MODERATEe due to indirectness RR 0.46?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is a MODERATEe due to indirectness RR 0.46?. ### Response: 12 months.


Instruction: What is the age-specific control rate taken from BATTLESCARRED usual care group?

Output: Downgraded by 1 increment if the majority of the evidence was at high risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age-specific control rate taken from BATTLESCARRED usual care group?. ### Response: Downgraded by 1 increment if the majority of the evidence was at high risk of bias.


Instruction: How many increments were downgraded if the majority of the evidence was at high risk of bias?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were downgraded if the majority of the evidence was at high risk of bias?. ### Response: 2.


Instruction: How much increments did downgrade the majority of evidence be at very high risk?

Output: 2 increments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much increments did downgrade the majority of evidence be at very high risk?. ### Response: 2 increments.


Instruction: If the confidence interval was high, how much increment was downgrade?

Output: 2 increments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the confidence interval was high, how much increment was downgrade?. ### Response: 2 increments.


Instruction: How many increments were downgraded if the confidence interval crossed one MID?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were downgraded if the confidence interval crossed one MID?. ### Response: 2.


Instruction: What was the age-specific control rate taken from?

Output: BATTLESCARRED usual care group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the age-specific control rate taken from?. ### Response: BATTLESCARRED usual care group.


Instruction: How many increments were downgraded because the outcome was an indirect indicator of the protocol outcome?

Output: one

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many increments were downgraded because the outcome was an indirect indicator of the protocol outcome?. ### Response: one.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertensi on in the Primary Care Setting March 2020 Page 130 of 134 60?

Output: Blood pressure reduction and  secondary stroke prevention: A systematic review and metaregression analysis of randomized clinical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertensi on in the Primary Care Setting March 2020 Page 130 of 134 60?. ### Response: Blood pressure reduction and  secondary stroke prevention: A systematic review and metaregression analysis of randomized clinical trials.


Instruction: What is the name of the systematic review and metaregression analysis of randomized clinical trials of stroke prevention?

Output: Blood pressure reduction and  secondary stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and metaregression analysis of randomized clinical trials of stroke prevention?. ### Response: Blood pressure reduction and  secondary stroke prevention.


Instruction: Hypertension. Jan 2017;69(1): 171-179.

Output: 171-179.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypertension. Jan 2017;69(1): 171-179.. ### Response: 171-179..


Instruction: What is blood pressure lowering treatment for?

Output: preventing recurrent stroke, major vascular events, and dementia in patients with a history of stroke or transient ischaemic attack

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is blood pressure lowering treatment for?. ### Response: preventing recurrent stroke, major vascular events, and dementia in patients with a history of stroke or transient ischaemic attack.


Instruction: What is a common cause of dementia in patients with a history of stroke or transient ischaemic attack?

Output: recurrent stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of dementia in patients with a history of stroke or transient ischaemic attack?. ### Response: recurrent stroke.


Instruction: What is the name of the Cochrane Database Syst Rev. Jul 19 2018;7:Cd007858.

Output: Blood pressure -lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients with a history of stroke or transient ischaemic attack. Cochrane Database Syst Rev. Jul 19 2018;7:Cd007858. PMID: 30024023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Cochrane Database Syst Rev. Jul 19 2018;7:Cd007858.. ### Response: Blood pressure -lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients with a history of stroke or transient ischaemic attack. Cochrane Database Syst Rev. Jul 19 2018;7:Cd007858. PMID: 30024023.