Instruction: How do people with heart failure due to valve disease receive specialist assessment and advice regarding follow up?

Output: Refer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do people with heart failure due to valve disease receive specialist assessment and advice regarding follow up?. ### Response: Refer.


Instruction: What should a person manage in accordance with this guideline only if the diagnosis is confirmed?

Output: care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a person manage in accordance with this guideline only if the diagnosis is confirmed?. ### Response: care.


Instruction: If the diagnosis of heart failure is still suspected, but confirmation of the underlying cardiac abnormality h as not occurred, then the person should have what?

Output: appropriate further investigation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the diagnosis of heart failure is still suspected, but confirmation of the underlying cardiac abnormality h as not occurred, then the person should have what?. ### Response: appropriate further investigation.


Instruction: What should the person have done?

Output: appropriate further investigation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the person have done?. ### Response: appropriate further investigation.


Instruction: What should have happened if the person did not have an investigation?

Output: appropriate further investigation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should have happened if the person did not have an investigation?. ### Response: appropriate further investigation.


Instruction: When did ACC/AHA/SCAI Focused Update on Primary PCI1243 occur?

Output: MARCH 15, 2016:1235 –50 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did ACC/AHA/SCAI Focused Update on Primary PCI1243 occur?. ### Response: MARCH 15, 2016:1235 –50 2015.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What does Mitral valve prolapse worsen rather than decrease severity of?

Output: MR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Mitral valve prolapse worsen rather than decrease severity of?. ### Response: MR.


Instruction: Why must hypertension be treated?

Output: because of the well-known morbidity and mortality associated with that condition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why must hypertension be treated?. ### Response: because of the well-known morbidity and mortality associated with that condition.


Instruction: What increases the systolic transmitral gradient and worsens severity of MR?

Output: increased LV systolic pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increases the systolic transmitral gradient and worsens severity of MR?. ### Response: increased LV systolic pressure.


Instruction: What are the studies that support the recommendations summarized in Online Data Supplement 30?

Output: InterventionRecommendations for Intervention for Chronic Primary MRReferenced

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the studies that support the recommendations summarized in Online Data Supplement 30?. ### Response: InterventionRecommendations for Intervention for Chronic Primary MRReferenced.


Instruction: In symptomatic patients with severe primary MR (Stage D), mitral valve intervention is recommended regardless of what function?

Output: LV systolic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In symptomatic patients with severe primary MR (Stage D), mitral valve intervention is recommended regardless of what function?. ### Response: LV systolic.


Instruction: What is recommended in asymptomatic patients with severe primary MR and LV systolic dysfunction?

Output: mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in asymptomatic patients with severe primary MR and LV systolic dysfunction?. ### Response: mitral valve surgery.


Instruction: What percentage of LVEF is 60%, LVESD 40 mm?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of LVEF is 60%, LVESD 40 mm?. ### Response: ≤.


Instruction: In patients who have severe primary MMR for whom surgery is indicated, mitral valve repair is preferred to what?

Output: mitral valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients who have severe primary MMR for whom surgery is indicated, mitral valve repair is preferred to what?. ### Response: mitral valve replacement.


Instruction: What is the anatomic cause of MR?

Output: degenerative disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the anatomic cause of MR?. ### Response: degenerative disease.


Instruction: What is recommended in preference to mitral valve replacement?

Output: mitral valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in preference to mitral valve replacement?. ### Response: mitral valve repair.


Instruction: In asymptomatic patients with severe primary MR and normal LV systolic function, what is recommended?

Output: mitral valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In asymptomatic patients with severe primary MR and normal LV systolic function, what is recommended?. ### Response: mitral valve surgery.


Instruction: What is the expected mortality rate of mitral valve repair?

Output: <1%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the expected mortality rate of mitral valve repair?. ### Response: <1%,.


Instruction: What is reasonable when the likelihood of a successful and durable repair without residual MR is >95%?

Output: mitral valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable when the likelihood of a successful and durable repair without residual MR is >95%?. ### Response: mitral valve repair.


Instruction: What type of valve surgery is indicated in asymptomatic patients with severe primary MR and normal LV systolic function?

Output: mitral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve surgery is indicated in asymptomatic patients with severe primary MR and normal LV systolic function?. ### Response: mitral.


Instruction: What percentage of LVEF is above 60% and LVESD 40 mm?

Output: ≤60%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of LVEF is above 60% and LVESD 40 mm?. ### Response: ≤60%,.


Instruction: What is TEER?

Output: transcatheter edge-to-edge repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TEER?. ### Response: transcatheter edge-to-edge repair.


Instruction: What type of imaging studies show that mitral valve surgery may be considered?

Output: ≥3 serial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of imaging studies show that mitral valve surgery may be considered?. ### Response: ≥3 serial.


Instruction: How long is the patient's life expectancy?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the patient's life expectancy?. ### Response: 1 year.


Instruction: In symptomatic patients with severe primary MR, what may be considered?

Output: mitral valve intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In symptomatic patients with severe primary MR, what may be considered?. ### Response: mitral valve intervention.


Instruction: What may be considered at a Comprehensive Valve Center when surgical treatment is indicated?

Output: mitral valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered at a Comprehensive Valve Center when surgical treatment is indicated?. ### Response: mitral valve repair.


Instruction: What is the Harm B-NR8?

Output: In patients with severe primary MR where leaflet pathology is limited to less than one half the posterior leaflet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Harm B-NR8?. ### Response: In patients with severe primary MR where leaflet pathology is limited to less than one half the posterior leaflet.


Instruction: In patients with severe primary MR where leaflet pathology is limited to less than what?

Output: one half the posterior leaflet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with severe primary MR where leaflet pathology is limited to less than what?. ### Response: one half the posterior leaflet.


Instruction: How much of the posterior leaflet does pathology limit?

Output: one half

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the posterior leaflet does pathology limit?. ### Response: one half.


Instruction: What should not be performed unless mitral valve repair has been attempted at a Primary or Comprehensive Valve Center and failed?

Output: mitral valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be performed unless mitral valve repair has been attempted at a Primary or Comprehensive Valve Center and failed?. ### Response: mitral valve replacement.


Instruction: What is the ratio of rivar -oxaban to P2Y12 inhibitor?

Output: 1:1:1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ratio of rivar -oxaban to P2Y12 inhibitor?. ### Response: 1:1:1.


Instruction: How long is the group 1 randomized to low-dose or high-dose?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the group 1 randomized to low-dose or high-dose?. ### Response: 12 months.


Instruction: For how long does the group 2 randomized receive a dose-adjusted vitamin K antagonist?

Output: 1, 6, or 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For how long does the group 2 randomized receive a dose-adjusted vitamin K antagonist?. ### Response: 1, 6, or 12 months.


Instruction: What was the most common P2Y12 inhibitor used?

Output: Clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the most common P2Y12 inhibitor used?. ### Response: Clopidogrel.


Instruction: What were the rates of clinical significant bleeding in Groups 1 and 2 than in Group 3?

Output: lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the rates of clinical significant bleeding in Groups 1 and 2 than in Group 3?. ### Response: lower.


Instruction: What were the rates of death from cardiovascular causes, MI, or stroke similar in the 3 groups?

Output: S7.4-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the rates of death from cardiovascular causes, MI, or stroke similar in the 3 groups?. ### Response: S7.4-2.


Instruction: What was lower than the dose recommended for stroke prophylaxis in AF?

Output: rivaroxaban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was lower than the dose recommended for stroke prophylaxis in AF?. ### Response: rivaroxaban.


Instruction: What was the dose recommended for stroke prophylaxis in AF?

Output: lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the dose recommended for stroke prophylaxis in AF?. ### Response: lower.


Instruction: What was not powered to evaluate risk of?

Output: stent thrombosis or systemic thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not powered to evaluate risk of?. ### Response: stent thrombosis or systemic thromboembolism.


Instruction: How many patients had undergone PCI with stenting?

Output: 725

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had undergone PCI with stenting?. ### Response: 725.


Instruction: What type of stenting is used in PCI?

Output: nonvalvular AF who had undergone PCI with stenting. Patients were randomized to receive 1 of 3 treatments: double therapy with dabigatran

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stenting is used in PCI?. ### Response: nonvalvular AF who had undergone PCI with stenting. Patients were randomized to receive 1 of 3 treatments: double therapy with dabigatran.


Instruction: How many treatments were patients randomized to receive?

Output: 1 of 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many treatments were patients randomized to receive?. ### Response: 1 of 3.


Instruction: What was the dose of dabigatran used for?

Output: 110 mg twice daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the dose of dabigatran used for?. ### Response: 110 mg twice daily.


Instruction: Which drug was used for double therapy?

Output: dabigatran

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug was used for double therapy?. ### Response: dabigatran.


Instruction: What is ticagrelor?

Output: 150-mg dual-therapy group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ticagrelor?. ### Response: 150-mg dual-therapy group.


Instruction: What is the inci-dence of major or clinically relevant nonmajor bleeding higher in the triple-therapy group?

Output: 110-mg dual-therapy group and the 150-mg dual-therapy group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the inci-dence of major or clinically relevant nonmajor bleeding higher in the triple-therapy group?. ### Response: 110-mg dual-therapy group and the 150-mg dual-therapy group.


Instruction: How much warfarin plus aspirin daily is required for triple therapy?

Output: ≤100 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much warfarin plus aspirin daily is required for triple therapy?. ### Response: ≤100 mg.


Instruction: What was noninferior to the triple-therapy group in terms of thromboembolic events?

Output: 2 dual-therapy groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was noninferior to the triple-therapy group in terms of thromboembolic events?. ### Response: 2 dual-therapy groups.


Instruction: What was not powered to evaluate risk of stent thrombosis?

Output: the study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not powered to evaluate risk of stent thrombosis?. ### Response: the study.


Instruction: How does double therapy reduce the risk of bleeding?

Output: without a signal of harm with re-gard to stent thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does double therapy reduce the risk of bleeding?. ### Response: without a signal of harm with re-gard to stent thrombosis.


Instruction: What did the RE-DUAL PCI trial and WOEST trials study?

Output: antithrombotic dosages

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the RE-DUAL PCI trial and WOEST trials study?. ### Response: antithrombotic dosages.


Instruction: What does stent thrombosis reduce without a signal of harm?

Output: risk of bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does stent thrombosis reduce without a signal of harm?. ### Response: risk of bleeding.


Instruction: What did the PCI and WOEST trials study?

Output: antithrombotic dosages

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the PCI and WOEST trials study?. ### Response: antithrombotic dosages.


Instruction: When was this article published?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 23, 2023.


Instruction: What is routine cholesterol surveillance in child-hood?

Output: Lipid screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is routine cholesterol surveillance in child-hood?. ### Response: Lipid screening.


Instruction: What is the name of the screening for familial hypercholes-terolemia?

Output: Statins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the screening for familial hypercholes-terolemia?. ### Response: Statins.


Instruction: What year did Pathology 44:122–8 appear?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Pathology 44:122–8 appear?. ### Response: 2012.


Instruction: What is the name of the National Institute for Health and Care Excellence (UK)?

Output: NICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the National Institute for Health and Care Excellence (UK)?. ### Response: NICE.


Instruction: Where is Familial hypercholesterolaemia: identification and management available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Familial hypercholesterolaemia: identification and management available?. ### Response: http://www.nice.org.uk/guidance/CG71.


Instruction: When was dyslipidemia and blood pressure among US children and adoles-cents?

Output: 1999–2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was dyslipidemia and blood pressure among US children and adoles-cents?. ### Response: 1999–2012.


Instruction: Blood pressure among US children and adoles-cents, 1999-2012 JAMA Pediatr. 2015;169:272-9. S4.4.4.3-26. May AL, Kuklina EV, Yoon PW, et al. Prevalence of cardiovascular dis-ease risk factors among US adolescents. 1999-2008 Pediatrics. 2012;129:1035-41. What did Lozano P, Henrikson NB, Morrison CC, and Morrison C do?

Output: dyslipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood pressure among US children and adoles-cents, 1999-2012 JAMA Pediatr. 2015;169:272-9. S4.4.4.3-26. May AL, Kuklina EV, Yoon PW, et al. Prevalence of cardiovascular dis-ease risk factors among US adolescents. 1999-2008 Pediatrics. 2012;129:1035-41. What did Lozano P, Henrikson NB, Morrison CC, and Morrison C do?. ### Response: dyslipidemia.


Instruction: What did the US Preventive Services Task Force use to detect multifactorial dys-lipidemia?

Output: Lipid screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the US Preventive Services Task Force use to detect multifactorial dys-lipidemia?. ### Response: Lipid screening.


Instruction: What is the name of the scientific statement from the American Heart Association?

Output: The agenda for familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the scientific statement from the American Heart Association?. ### Response: The agenda for familial hypercholesterolemia.


Instruction: What is the name of the scientific statement released by the American Heart Association?

Output: The agenda for familial hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the scientific statement released by the American Heart Association?. ### Response: The agenda for familial hypercholesterolemia.


Instruction: What is a lipid screening in child-hood and adolescence for?

Output: detection of multifactorial dys-lipidemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a lipid screening in child-hood and adolescence for?. ### Response: detection of multifactorial dys-lipidemia.


Instruction: What is atorvas-tatin used for in children with lupus erythematosus?

Output: reduce atherosclerosis pro-gression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atorvas-tatin used for in children with lupus erythematosus?. ### Response: reduce atherosclerosis pro-gression.


Instruction: What is Ardoin used for?

Output: Secondary analysis of APPLE study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Ardoin used for?. ### Response: Secondary analysis of APPLE study.


Instruction: What is erythematosus in children and adolescents?

Output: systemic lupus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is erythematosus in children and adolescents?. ### Response: systemic lupus.


Instruction: Arthritis Rheum. 2012;64:285–96. S4.4.4.3-32.

Output: 2016;316:634–44

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arthritis Rheum. 2012;64:285–96. S4.4.4.3-32.. ### Response: 2016;316:634–44.


Instruction: What may reduce atherosclerosis pro-gression in pubertal lupus patients with higher C reactive protein?

Output: atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may reduce atherosclerosis pro-gression in pubertal lupus patients with higher C reactive protein?. ### Response: atorvastatin.


Instruction: What is the phenotype of ath-erosclerotic cardiovascular disease in US adults with familial hypercholesterolemia?

Output: Long-term risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the phenotype of ath-erosclerotic cardiovascular disease in US adults with familial hypercholesterolemia?. ### Response: Long-term risk.


Instruction: What is a risk factor for non-coronary heart disease mortality and cancer in patients with treated heart disease?

Output: familial hypercholesterolaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for non-coronary heart disease mortality and cancer in patients with treated heart disease?. ### Response: familial hypercholesterolaemia.


Instruction: What is the risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia?

Output: Non-coronary heart disease mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia?. ### Response: Non-coronary heart disease mortality.


Instruction: What was the name of the prospective regis-try study?

Output: Non-coronary heart disease mortality and risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the prospective regis-try study?. ### Response: Non-coronary heart disease mortality and risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia.


Instruction: When was the Atherosclerosis.179:293–7?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Atherosclerosis.179:293–7?. ### Response: 2005.


Instruction: What year was the 63rd issue of the journal 63:1935-47?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the 63rd issue of the journal 63:1935-47?. ### Response: 2014.


Instruction: What is the name of the study that focuses on cholesterol screening?

Output: S4.4.4.3-21

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that focuses on cholesterol screening?. ### Response: S4.4.4.3-21.


Instruction: What is the name of the seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment ofHigh Blood Pressure143?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment ofHigh Blood Pressure143?. ### Response: 2003.


Instruction: What type of CKD is ACE-I or ARB incombination with a diuretic?

Output: Stage 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of CKD is ACE-I or ARB incombination with a diuretic?. ### Response: Stage 3.


Instruction: What type 2 DM with nephropathy is ARBN?

Output: ACE-IType

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type 2 DM with nephropathy is ARBN?. ### Response: ACE-IType.


Instruction: What type of DM with nephropathy is ACE-IType 2?

Output: DiureticType 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of DM with nephropathy is ACE-IType 2?. ### Response: DiureticType 1.


Instruction: What is the name of the European Society of Hypertension guidelines for the management of arterial hypertension236?

Output: European Society ofCardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the European Society of Hypertension guidelines for the management of arterial hypertension236?. ### Response: European Society ofCardiology.


Instruction: What is the name of the organization that cares for Australasian with Renal Impairment?

Output: Caring for Australasians with Renal Impairment (CARI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that cares for Australasian with Renal Impairment?. ### Response: Caring for Australasians with Renal Impairment (CARI.


Instruction: What is more effective than those not including ACE-I in slowing CKDprogression in non-DKDCombination therapy?

Output: Regimens including ACE-I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more effective than those not including ACE-I in slowing CKDprogression in non-DKDCombination therapy?. ### Response: Regimens including ACE-I.


Instruction: What is ACE-I more effective than beta-blockers and dihydropyridine CCB in slowing CKDprogression?

Output: CKDBeta-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACE-I more effective than beta-blockers and dihydropyridine CCB in slowing CKDprogression?. ### Response: CKDBeta-blockers.


Instruction: What is ACE-I for all patients with diabetes andhypertension?

Output: microalbuminuria or overt nephropathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACE-I for all patients with diabetes andhypertension?. ### Response: microalbuminuria or overt nephropathy.


Instruction: What provides specific renoprotection indiabetic nephropathy, beyond theiranti-hypertensive benefit?

Output: GFRARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provides specific renoprotection indiabetic nephropathy, beyond theiranti-hypertensive benefit?. ### Response: GFRARB.


Instruction: What type of nephropathy has a specificbenefit?

Output: DM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of nephropathy has a specificbenefit?. ### Response: DM.


Instruction: What is the Canadian Society of Nephrology Guidelines onManagement of CKD?

Output: Prevention of Progression of Kidney Disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Canadian Society of Nephrology Guidelines onManagement of CKD?. ### Response: Prevention of Progression of Kidney Disease.


Instruction: How many Stroke December 2014 616?

Output: 3824

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Stroke December 2014 616?. ### Response: 3824.


Instruction: What is the Executive Summary of the Third Report of the National Cholesterol Education Program?

Output: Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Executive Summary of the Third Report of the National Cholesterol Education Program?. ### Response: Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults.


Instruction: What is High Blood Cholesterol in Adults?

Output: Adult Treatment Panel III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is High Blood Cholesterol in Adults?. ### Response: Adult Treatment Panel III.


Instruction: When did JAMA issue 285:2486-2497?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 285:2486-2497?. ### Response: 2001.


Instruction: What is the focus of the statement for professionals from the American Heart Association Council?

Output: cardio-vascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the statement for professionals from the American Heart Association Council?. ### Response: cardio-vascular disease.


Instruction: What is the acronym for the American Heart Association Council on Nutrition, Physical Activity, and Metabolism?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American Heart Association Council on Nutrition, Physical Activity, and Metabolism?. ### Response: American Heart Association.


Instruction: When was the Circulation.110:2952-2967 published?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.110:2952-2967 published?. ### Response: 2004.


Instruction: What is a new worldwide definition of the metabolic syndrome?

Output: The metabolic syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a new worldwide definition of the metabolic syndrome?. ### Response: The metabolic syndrome.


Instruction: What does the International Diabetes Federation Task Force on Epidemiology and Prevention do?

Output: Harmonizing the metabolic syn-drome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the International Diabetes Federation Task Force on Epidemiology and Prevention do?. ### Response: Harmonizing the metabolic syn-drome.


Instruction: What is the acronym for the International Association for the Prevention of Diabetes?

Output: National Cholesterol Education Program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the International Association for the Prevention of Diabetes?. ### Response: National Cholesterol Education Program.


Instruction: Who is the International Atherosclerosis Society?

Output: American Heart Association; World Heart Federation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the International Atherosclerosis Society?. ### Response: American Heart Association; World Heart Federation.


Instruction: World Heart Federation, International Atherosclerosis Society, International Association for the Study of Obesity, and National Heart, Lung and Blood Institute have a joint interim statement on what?

Output: Harmonizing the metabolic syn-drome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: World Heart Federation, International Atherosclerosis Society, International Association for the Study of Obesity, and National Heart, Lung and Blood Institute have a joint interim statement on what?. ### Response: Harmonizing the metabolic syn-drome.


Instruction: Harmonizing the metabolic syn-drome of the International Diabetes Federation Task Force on Epidemiology and Prevention has a Joint Interim Statement on What?

Output: Epidemiology and Prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Harmonizing the metabolic syn-drome of the International Diabetes Federation Task Force on Epidemiology and Prevention has a Joint Interim Statement on What?. ### Response: Epidemiology and Prevention.


Instruction: What is the acronym for the International Association for the Study of Obesity?

Output: Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the International Association for the Study of Obesity?. ### Response: Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society.


Instruction: When did Circulation. 2009:120:1640–1645?

Output: 620

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2009:120:1640–1645?. ### Response: 620.


Instruction: What was the name of the association that studies the metabolic syndrome in middle-aged men?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the association that studies the metabolic syndrome in middle-aged men?. ### Response: JAMA.


Instruction: What is mortality in middle-aged men?

Output: cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is mortality in middle-aged men?. ### Response: cardiovascular disease.


Instruction: What is the name of the disease that is associated with the metabolic syndrome?

Output: cardiovascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that is associated with the metabolic syndrome?. ### Response: cardiovascular.


Instruction: When did the Lancet issue 365:1415-1428 appear?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet issue 365:1415-1428 appear?. ### Response: 2005.


Instruction: What are the continuing epidemics of obesity and diabetes in the US?

Output: JAMA. 2001;286:1195–1200

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the continuing epidemics of obesity and diabetes in the US?. ### Response: JAMA. 2001;286:1195–1200.


Instruction: What is the JAMA's 2001286:1195–1200?

Output: 285:2486–2497

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JAMA's 2001286:1195–1200?. ### Response: 285:2486–2497.


Instruction: How does Eckel RH manage obesity in adults?

Output: nonsurgical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Eckel RH manage obesity in adults?. ### Response: nonsurgical.


Instruction: Med. 2008;358:1941-1950.

Output: N Engl J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Med. 2008;358:1941-1950.. ### Response: N Engl J.


Instruction: Flegal KM, Kit BK, Orpana H, Graubard BI. What is the association of all-cause mortality with overweight and obesity using standard body mass index categories?

Output: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Flegal KM, Kit BK, Orpana H, Graubard BI. What is the association of all-cause mortality with overweight and obesity using standard body mass index categories?. ### Response: a systematic review and meta-analysis.


Instruction: JAMA. 2013;309:71–82.

Output: 626

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: JAMA. 2013;309:71–82.. ### Response: 626.


Instruction: What is the name of the metabolic syndrome?

Output: syn-drome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the metabolic syndrome?. ### Response: syn-drome.


Instruction: What is a harmonious definition of metabolic syndrome among adults in the US?

Output: syn-drome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a harmonious definition of metabolic syndrome among adults in the US?. ### Response: syn-drome.


Instruction: How many people in the U.S. have metabolic syndromes?

Output: 620

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people in the U.S. have metabolic syndromes?. ### Response: 620.


Instruction: What is the name of the diabetes journal in the U.S.?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the diabetes journal in the U.S.?. ### Response: JAMA.


Instruction: Which diabetes journal published a study in 2010?

Output: J Diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which diabetes journal published a study in 2010?. ### Response: J Diabetes.


Instruction: What is a rationale for optimizing surgical indications?

Output: regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a rationale for optimizing surgical indications?. ### Response: regurgitation.


Instruction: When did Circulation. 1999:400-5?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 1999:400-5?. ### Response: 1999.


Instruction: What should patients with severe degenerative mitral regurgitation delay surgery until symptoms develop?

Output: watchful waiting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with severe degenerative mitral regurgitation delay surgery until symptoms develop?. ### Response: watchful waiting.


Instruction: What is the outcome of watchful waiting in as-ymptomatic severe mitral regurgitation?

Output: Outcome of watchful waiting in as-ymptomatic severe mitral regurgitation. Circulation. 2006;113:2238–44

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the outcome of watchful waiting in as-ymptomatic severe mitral regurgitation?. ### Response: Outcome of watchful waiting in as-ymptomatic severe mitral regurgitation. Circulation. 2006;113:2238–44.


Instruction: What was the Circulation. 2006;113:2238-44?

Output: Outcome of watchful waiting in as-ymptomatic severe mitral regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Circulation. 2006;113:2238-44?. ### Response: Outcome of watchful waiting in as-ymptomatic severe mitral regurgitation.


Instruction: How did Kang D-H, Kim JH, Rim JH compare early surgery versus conventional treatment?

Output: Comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Kang D-H, Kim JH, Rim JH compare early surgery versus conventional treatment?. ### Response: Comparison.


Instruction: What is the temporal response of left ven-tricular performance to mitral valve surgery?

Output: 5. Schuler G, Peterson KL, Johnson A, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the temporal response of left ven-tricular performance to mitral valve surgery?. ### Response: 5. Schuler G, Peterson KL, Johnson A, et al.


Instruction: What is Echocardiographic predic-tion of survival after surgical correction of organic mitral regurgitation?

Output: 830–7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Echocardiographic predic-tion of survival after surgical correction of organic mitral regurgitation?. ### Response: 830–7.


Instruction: What is the survival implication of left ven-tricular end-systolic diameter in mitral regurgitation due to flail leaflets?

Output: early surgical intervention vs watchful waiting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the survival implication of left ven-tricular end-systolic diameter in mitral regurgitation due to flail leaflets?. ### Response: early surgical intervention vs watchful waiting.


Instruction: What is a long-term follow-up multicenter study?

Output: Survival implication of left ven-tricular end-systolic diameter in mitral regurgitation due to flail leaflets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a long-term follow-up multicenter study?. ### Response: Survival implication of left ven-tricular end-systolic diameter in mitral regurgitation due to flail leaflets.


Instruction: What are the determinants of the outcome of asymptomatic mitral regurgitation?

Output: watchful waiting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the determinants of the outcome of asymptomatic mitral regurgitation?. ### Response: watchful waiting.


Instruction: What is Crawford MH, Souchek J, Oprian CA, et al. Determinants of survival after mitral valve replacement.

Output: left ventricular performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Crawford MH, Souchek J, Oprian CA, et al. Determinants of survival after mitral valve replacement.. ### Response: left ventricular performance.


Instruction: What is a predictor of postoperative left ventricular performance in volume overload from valvu-lar regurgitation?

Output: End-systolic volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of postoperative left ventricular performance in volume overload from valvu-lar regurgitation?. ### Response: End-systolic volume.


Instruction: What is the name of the study on Valvular Heart Disease. Circulation. 1990;81:1173–81.

Output: Department of Veterans Affairs Cooperative Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study on Valvular Heart Disease. Circulation. 1990;81:1173–81.. ### Response: Department of Veterans Affairs Cooperative Study.


Instruction: What is the effect of recurrent mitral regurgitation following degenerative mitral valve repair?

Output: long-term analysis of competing outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of recurrent mitral regurgitation following degenerative mitral valve repair?. ### Response: long-term analysis of competing outcomes.


Instruction: What was the J Am Coll Cardiol 201667:488–98?

Output: Effect of recurrent mitral regurgi-tation following degenerative mitral valve repair: long-term analysis of competing outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol 201667:488–98?. ### Response: Effect of recurrent mitral regurgi-tation following degenerative mitral valve repair: long-term analysis of competing outcomes.


Instruction: How did Vassileva CM, Mishkel G, McNeely C, et al. compare Medicare fee-for-service?

Output: longitudinal analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did Vassileva CM, Mishkel G, McNeely C, et al. compare Medicare fee-for-service?. ### Response: longitudinal analysis.


Instruction: What is a longitudinal analysis of Medicare fee-for-service beneficiaries?

Output: Long-term survival of patients undergoing mitral valve repair and replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a longitudinal analysis of Medicare fee-for-service beneficiaries?. ### Response: Long-term survival of patients undergoing mitral valve repair and replacement.


Instruction: What is an association between early surgical intervention vs watchful waiting and outcomes for mitral regurgitation?

Output: flail mitral valve leaflets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an association between early surgical intervention vs watchful waiting and outcomes for mitral regurgitation?. ### Response: flail mitral valve leaflets.


Instruction: What is the name of the multicenter European study on mitral regurgita-tion due to flail leaflets?

Output: JACC Cardiovasc Imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter European study on mitral regurgita-tion due to flail leaflets?. ### Response: JACC Cardiovasc Imaging.


Instruction: How long does it take for mitral repair versus replacement to be successful?

Output: Twenty-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for mitral repair versus replacement to be successful?. ### Response: Twenty-year.


Instruction: What type of repair versus replacement for severe degenerative mitral regur?

Output: mitral repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of repair versus replacement for severe degenerative mitral regur?. ### Response: mitral repair.


Instruction: What is the purpose of this study?

Output: long-term follow-up multicenter study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of this study?. ### Response: long-term follow-up multicenter study.


Instruction: How is left ventricular function predicted?

Output: End-systolic volume

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is left ventricular function predicted?. ### Response: End-systolic volume.


Instruction: What does Domiciliary oxygen therapy do in people with advanced heart failure?

Output: ICD deactivation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Domiciliary oxygen therapy do in people with advanced heart failure?. ### Response: ICD deactivation.


Instruction: What is the ISBN number for heart failure and palliative care?

Output: 978 -1-4731 -3093 -7 421 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ISBN number for heart failure and palliative care?. ### Response: 978 -1-4731 -3093 -7 421 10.


Instruction: When was the heart failure guideline published?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the heart failure guideline published?. ### Response: 2010.


Instruction: When was a review of new evidence carried out?

Output: after 20 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a review of new evidence carried out?. ### Response: after 20 10.


Instruction: What was done to determine if any changes to current recommendations were required?

Output: A review of new evidence published after 20 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was done to determine if any changes to current recommendations were required?. ### Response: A review of new evidence published after 20 10.


Instruction: What are the current recommendations where likely to be required?

Output: ICD deactivation in patients with advanced heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the current recommendations where likely to be required?. ### Response: ICD deactivation in patients with advanced heart failure.


Instruction: What was the decision on which topics to include in the update of the guideline made after?

Output: diuretics,  domiciliary oxygen therapy  and criteria for discussing ICD deactivation in patients with advanced heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the decision on which topics to include in the update of the guideline made after?. ### Response: diuretics,  domiciliary oxygen therapy  and criteria for discussing ICD deactivation in patients with advanced heart failure.


Instruction: In this section new evi dence was reviewed on the use of what?

Output: diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In this section new evi dence was reviewed on the use of what?. ### Response: diuretics.


Instruction: What is used to discuss ICD deactivation in patients with advanced heart failure?

Output: criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to discuss ICD deactivation in patients with advanced heart failure?. ### Response: criteria.


Instruction: What is the use of validated risk tools to identify patients with an increased risk of mortality?

Output: diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use of validated risk tools to identify patients with an increased risk of mortality?. ### Response: diuretics.


Instruction: What is the only group of medication where there is consensus about its benefit in relieving the breathlessness in patients with heart failure?

Output: IV diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the only group of medication where there is consensus about its benefit in relieving the breathlessness in patients with heart failure?. ### Response: IV diuretics.


Instruction: What is undoubtedly helpful in cases of systemic fluid overload or pulmonary congestion?

Output: diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is undoubtedly helpful in cases of systemic fluid overload or pulmonary congestion?. ### Response: diuretics.


Instruction: What is the brea thlessness in patients with heart failure with preserved left ventricular ejection fraction (HFPEF)?

Output: relieving

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the brea thlessness in patients with heart failure with preserved left ventricular ejection fraction (HFPEF)?. ### Response: relieving.


Instruction: What is most cost effective for patients with advanced heart failure receiving palliative care in the community?

Output: diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is most cost effective for patients with advanced heart failure receiving palliative care in the community?. ### Response: diuretics.


Instruction: Which route of administration of diuretics is most clinically and cost effective in people with advanced heart failure who are in the community?

Output: subcutaneous or oral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which route of administration of diuretics is most clinically and cost effective in people with advanced heart failure who are in the community?. ### Response: subcutaneous or oral.


Instruction: What type of care is included in palliative care?

Output: subcutaneous or oral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care is included in palliative care?. ### Response: subcutaneous or oral.


Instruction: What is a PICO characteristic of the review question Population Advanced heart failure in the community Interventions / comparators  IV diuretics (furosemide or torsemide) + what?

Output: oral metolazone/thiazides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a PICO characteristic of the review question Population Advanced heart failure in the community Interventions / comparators  IV diuretics (furosemide or torsemide) + what?. ### Response: oral metolazone/thiazides.


Instruction: What is another name for IV diuretics?

Output: intravenous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for IV diuretics?. ### Response: intravenous.


Instruction: What is a different name for a bolus or a continuous diuretic?

Output: furosemide or torsemide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a different name for a bolus or a continuous diuretic?. ### Response: furosemide or torsemide.


Instruction: How are the different types of diurestics compared?

Output: subcutaneous or oral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the different types of diurestics compared?. ### Response: subcutaneous or oral.


Instruction: Bendroflumethiazide is also known as what?

Output: Bendrofluazide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bendroflumethiazide is also known as what?. ### Response: Bendrofluazide.


Instruction: What is the name of the drug that is used to treat unplanned hospitalization?

Output: Metolazone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat unplanned hospitalization?. ### Response: Metolazone.


Instruction: Xipamide is an example of what drug?

Output: Indapamide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Xipamide is an example of what drug?. ### Response: Indapamide.


Instruction: What is Ivabradine used for in patients with inappropriate sinus tachycardia?

Output: sinus node modification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Ivabradine used for in patients with inappropriate sinus tachycardia?. ### Response: sinus node modification.


Instruction: What is a guide for radiofrequency catheter ablation?

Output: activation mapping

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a guide for radiofrequency catheter ablation?. ### Response: activation mapping.


Instruction: What is guided by activation mapping in sinus tachycardia?

Output: Radiofrequency catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is guided by activation mapping in sinus tachycardia?. ### Response: Radiofrequency catheter ablation.


Instruction: What is noncontact mapping and saline-cooled ablation catheter used for?

Output: sinus node modification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is noncontact mapping and saline-cooled ablation catheter used for?. ### Response: sinus node modification.


Instruction: When did Pacing Clin Electrophysiol. 2007:30:236–42?

Output: 179

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Pacing Clin Electrophysiol. 2007:30:236–42?. ### Response: 179.


Instruction: What year did Clin Electrophysiol publish a report on radiofrequency catheter modification of the sinus node for inappropriate sinus tachycardia?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Clin Electrophysiol publish a report on radiofrequency catheter modification of the sinus node for inappropriate sinus tachycardia?. ### Response: 2007.


Instruction: When was this report published?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this report published?. ### Response: April 23, 2023.


Instruction: What is the name of the journal that published this report?

Output: ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published this report?. ### Response: ahajournals.org.


Instruction: What are reviewers required to complete and submit?

Output: Questionnaire

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are reviewers required to complete and submit?. ### Response: Questionnaire.


Instruction: What is a relationship considered to be if the person receives $10 000 or more during a 12-month period?

Output: significant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if the person receives $10 000 or more during a 12-month period?. ### Response: significant.


Instruction: How much of the voting stock or share of the entity does the person own?

Output: 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the voting stock or share of the entity does the person own?. ### Response: 5%.


Instruction: What is a relationship considered to be if it is less than “significant” under the preceding definition?

Output: modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if it is less than “significant” under the preceding definition?. ### Response: modest.


Instruction: What is less than “significant” under the preceding definition?

Output: A relationship is considered to be “modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less than “significant” under the preceding definition?. ### Response: A relationship is considered to be “modest.


Instruction: When was this document downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this document downloaded?. ### Response: April 28, 2023.


Instruction: What is the date of publication of Circulation. 2019:139:e1082–e1143?

Output: June 18/25, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the date of publication of Circulation. 2019:139:e1082–e1143?. ### Response: June 18/25, 2019.


Instruction: What does the term "Hispanic/Latino" refer to?

Output: Mexican-Americans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the term "Hispanic/Latino" refer to?. ### Response: Mexican-Americans.


Instruction: What may explain ASCVD risk factor burden more precisely than the generic term Hispanic/Latino?

Output: Race/ethnic-ity and country of origin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may explain ASCVD risk factor burden more precisely than the generic term Hispanic/Latino?. ### Response: Race/ethnic-ity and country of origin.


Instruction: Native American/Alas-kan natives have high rates of what?

Output: risk factors for ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Native American/Alas-kan natives have high rates of what?. ### Response: risk factors for ASCVD.


Instruction: What does the increase in metabolic risk factors and propensity for dia-betes mellitus resemble?

Output: the risk profiles of those who identify as Mexican-Americans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the increase in metabolic risk factors and propensity for dia-betes mellitus resemble?. ### Response: the risk profiles of those who identify as Mexican-Americans.


Instruction: What does the metabolic risk factors and propensity for dia-betes mellitus resemble?

Output: the risk profiles of those who identify as Mexican-Americans

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the metabolic risk factors and propensity for dia-betes mellitus resemble?. ### Response: the risk profiles of those who identify as Mexican-Americans.


Instruction: What does Table 10 review?

Output: racial/ethnic issues that may be useful in clinical management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Table 10 review?. ### Response: racial/ethnic issues that may be useful in clinical management.


Instruction: Where are references to studies that support recommendations summarized?

Output: Online Data Supplements 31 and 32

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are references to studies that support recommendations summarized?. ### Response: Online Data Supplements 31 and 32.


Instruction: What should clinicians address and treat in adults 20 years of age or older with moderate hypertriglyceridemia?

Output: lifestyle factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should clinicians address and treat in adults 20 years of age or older with moderate hypertriglyceridemia?. ### Response: lifestyle factors.


Instruction: What are two lifestyle factors?

Output: obesity and metabolic syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two lifestyle factors?. ### Response: obesity and metabolic syndrome.


Instruction: What is a secondary factor for diabetes mellitus?

Output: chronic liver or kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a secondary factor for diabetes mellitus?. ### Response: chronic liver or kidney disease.


Instruction: What is higher in non-Hispanic white men when compared to blacks, Latinos, and Chinese Americans?

Output: CAC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is higher in non-Hispanic white men when compared to blacks, Latinos, and Chinese Americans?. ### Response: CAC.


Instruction: South Asian women had similar CAC scores to whites and other racial/ethnic women although CAC burden higher in older age?

Output: S4.5.1-31CAC predicts similarly in whites and in those who identify as Hispanic/Latino

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: South Asian women had similar CAC scores to whites and other racial/ethnic women although CAC burden higher in older age?. ### Response: S4.5.1-31CAC predicts similarly in whites and in those who identify as Hispanic/Latino.


Instruction: In MESA, what was the highest CAC score in MESA?

Output: white and Hispanic men

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In MESA, what was the highest CAC score in MESA?. ### Response: white and Hispanic men.


Instruction: What was the highest CAC score in white and Hispanic men in MESA?

Output: CAC score was highest in white and Hispanic men, with blacks having significantly lower prevalence and severity of CAC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the highest CAC score in white and Hispanic men in MESA?. ### Response: CAC score was highest in white and Hispanic men, with blacks having significantly lower prevalence and severity of CAC.


Instruction: What race had significantly lower prevalence and severity of CAC?

Output: blacks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What race had significantly lower prevalence and severity of CAC?. ### Response: blacks.


Instruction: What type of diets can be used to avoid weight gain and address BP and lipids?

Output: hearthealthy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diets can be used to avoid weight gain and address BP and lipids?. ### Response: hearthealthy.


Instruction: What is a hearthealthy diet consistent with?

Output: racial/ethnic preferences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a hearthealthy diet consistent with?. ### Response: racial/ethnic preferences.


Instruction: What do you need to avoid weight gain and address with lifestyle counseling?

Output: BP and lipids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do you need to avoid weight gain and address with lifestyle counseling?. ### Response: BP and lipids.


Instruction: What groups need to be disaggregated?

Output: Asian and Hispanic/Latino

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What groups need to be disaggregated?. ### Response: Asian and Hispanic/Latino.


Instruction: BP and lipids need to be disaggregated because of what?

Output: hypertriglyceridemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BP and lipids need to be disaggregated because of what?. ### Response: hypertriglyceridemia.


Instruction: What is the challenge to avoid increased sodium, sugar, and calories as groups acculturate?

Output: Asian and Hispanic/Latino groups need to be disaggregated because of regional differences in lifestyle preferences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the challenge to avoid increased sodium, sugar, and calories as groups acculturate?. ### Response: Asian and Hispanic/Latino groups need to be disaggregated because of regional differences in lifestyle preferences.


Instruction: Christopher B. GrangerDuke Clinical Research Institute; Duke University—Professor of Medicine; Director, Cardiac Care Unit?

Output: Clinical Cardiac EP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Christopher B. GrangerDuke Clinical Research Institute; Duke University—Professor of Medicine; Director, Cardiac Care Unit?. ### Response: Clinical Cardiac EP.


Instruction: Who is Professor Emeritus of Medicine at Mayo Clinic?

Output: Stephen C. Hammill

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Professor Emeritus of Medicine at Mayo Clinic?. ### Response: Stephen C. Hammill.


Instruction: What is the name of the Stanford University School of Medicine?

Output: Mark A. Hlatky

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Stanford University School of Medicine?. ### Response: Mark A. Hlatky.


Instruction: Who is the Professor of Internal Medicine at UT Southwestern Medical Center?

Output: José A. Joglar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Professor of Internal Medicine at UT Southwestern Medical Center?. ### Response: José A. Joglar.


Instruction: What is the name of the professor who is the professor of Clinical Cardiac EP?

Output: Michael E. Field

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor who is the professor of Clinical Cardiac EP?. ### Response: Michael E. Field.


Instruction: Which professor of medicine at Stanford University is a professor of Cardiovascular Medicine?

Output: Mark A. Hlatky

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which professor of medicine at Stanford University is a professor of Cardiovascular Medicine?. ### Response: Mark A. Hlatky.


Instruction: Who is Professor Emeritus at the University of Alabama at Birmingham?

Output: G. Neal Kay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Professor Emeritus at the University of Alabama at Birmingham?. ### Response: G. Neal Kay.


Instruction: Who is Director of Clinical EP and Cardiac Arrhythmia Service, Associate Professor of Medicine?

Output: Michael E. Field

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Director of Clinical EP and Cardiac Arrhythmia Service, Associate Professor of Medicine?. ### Response: Michael E. Field.


Instruction: What is the name of the website that MedicineNone None None none None None None Downloaded from on April 23, 2023?

Output: ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the website that MedicineNone None None none None None None Downloaded from on April 23, 2023?. ### Response: ahajournals.org.


Instruction: How many times was Medicinenone none none none None none none downloaded from http://ahajournals.org?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many times was Medicinenone none none none None none none downloaded from http://ahajournals.org?. ### Response: April 23, 2023.


Instruction: What is the sensitivity and specificity of TTE for diagnosis of Type A3 aortic dissection?

Output: 60% to 80%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sensitivity and specificity of TTE for diagnosis of Type A3 aortic dissection?. ### Response: 60% to 80%,.


Instruction: TEE has a sensitivity of 98% to what percentage?

Output: 100%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: TEE has a sensitivity of 98% to what percentage?. ### Response: 100%.


Instruction: What should be considered only when considering angiog-raphy?

Output: when the diagno-sis cannot be determined by noninvasive imaging or when the differential diagnosis is an acute coronary syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered only when considering angiog-raphy?. ### Response: when the diagno-sis cannot be determined by noninvasive imaging or when the differential diagnosis is an acute coronary syndrome.


Instruction: What is the specificity of angiog-raphy?

Output: Each of these stages is defined by valve anatomy, valve hemodynamics, se-verity of LV dilation, and LV systolic function, as well as by patient symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the specificity of angiog-raphy?. ### Response: Each of these stages is defined by valve anatomy, valve hemodynamics, se-verity of LV dilation, and LV systolic function, as well as by patient symptoms.


Instruction: What should be considered only when the diagno-sis cannot be determined by noninvasive imaging or when the differential diagnosis is an acute coronary syndrome?

Output: Angiog-raphy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered only when the diagno-sis cannot be determined by noninvasive imaging or when the differential diagnosis is an acute coronary syndrome?. ### Response: Angiog-raphy.


Instruction: What is contraindicated in patients with acute severe AR?

Output: Intra-aortic balloon counterpulsation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is contraindicated in patients with acute severe AR?. ### Response: Intra-aortic balloon counterpulsation.


Instruction: Beta blockers are often used in treating what?

Output: aortic dis-section

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beta blockers are often used in treating what?. ### Response: aortic dis-section.


Instruction: What is often used in treating aortic dis-section?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often used in treating aortic dis-section?. ### Response: Beta blockers.


Instruction: What should be used very cautiously for other causes of acute AR?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used very cautiously for other causes of acute AR?. ### Response: Beta blockers.


Instruction: What is the most common cause of chronic severe AR in the United States and other high-income countries?

Output: BAV disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common cause of chronic severe AR in the United States and other high-income countries?. ### Response: BAV disease.


Instruction: BAV disease and primary diseases of the ascending aorta or the sinuses of Valsalva are the two most common causes of what?

Output: chronic severe AR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BAV disease and primary diseases of the ascending aorta or the sinuses of Valsalva are the two most common causes of what?. ### Response: chronic severe AR.


Instruction: Rheumatic heart disease is the leading cause of what in many areas?

Output: AR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Rheumatic heart disease is the leading cause of what in many areas?. ### Response: AR.


Instruction: What is the leading cause of AR in many low- to middle-income countries?

Output: Rheumatic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the leading cause of AR in many low- to middle-income countries?. ### Response: Rheumatic heart disease.


Instruction: What is regurgitation often accompanies with AS?

Output: calcific valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is regurgitation often accompanies with AS?. ### Response: calcific valve disease.


Instruction: In most patients with AR, the disease course is chronic and slowly what?

Output: progressive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In most patients with AR, the disease course is chronic and slowly what?. ### Response: progressive.


Instruction: What is the disease course of AR?

Output: chronic and slowly progressive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the disease course of AR?. ### Response: chronic and slowly progressive.


Instruction: What are two ways AR can be managed?

Output: severe asymptomatic (Stage C) and symptomatic (Stage D) AR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two ways AR can be managed?. ### Response: severe asymptomatic (Stage C) and symptomatic (Stage D) AR.


Instruction: How is AR diagnosed?

Output: accurate diagnosis of the cause and stage of the disease process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is AR diagnosed?. ### Response: accurate diagnosis of the cause and stage of the disease process.


Instruction: How many stages of AR are shown?

Output: 15

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many stages of AR are shown?. ### Response: 15.


Instruction: What is the stage A of AR?

Output: patients at risk of AR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the stage A of AR?. ### Response: patients at risk of AR.


Instruction: How is the Stage B of AR defined?

Output: by valve anatomy, valve hemodynamics, se-verity of LV dilation, and LV systolic function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the Stage B of AR defined?. ### Response: by valve anatomy, valve hemodynamics, se-verity of LV dilation, and LV systolic function.


Instruction: What is the name of the journal that provides information on valve anatomy and hemodynamics?

Output: ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that provides information on valve anatomy and hemodynamics?. ### Response: ahajournals.org.


Instruction: On what date was the journal downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was the journal downloaded?. ### Response: April 28, 2023.


Instruction: 1.5.3 Ensur e that t he person's condition is stable f or typically how long after starting beta-blockers?

Output: 48  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1.5.3 Ensur e that t he person's condition is stable f or typically how long after starting beta-blockers?. ### Response: 48  hours.


Instruction: 1.5.4 Offer an angiot ensin-con verting enzyme inhibit or what else if a person is in stable condition?

Output: s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1.5.4 Offer an angiot ensin-con verting enzyme inhibit or what else if a person is in stable condition?. ### Response: s.


Instruction: What is an angiot ensin-converting enzyme called?

Output: aldost erone antagonist s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an angiot ensin-converting enzyme called?. ### Response: aldost erone antagonist s.


Instruction: What is a side effect of using an aldost erone antagonist during hospital admission?

Output: hear t failure and r educed left v entricular ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a side effect of using an aldost erone antagonist during hospital admission?. ### Response: hear t failure and r educed left v entricular ejection fraction.


Instruction: What should be offered if the angiot ensin-converting enzyme is not inhibited?

Output: an aldost erone antagonist should still be off ered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be offered if the angiot ensin-converting enzyme is not inhibited?. ### Response: an aldost erone antagonist should still be off ered.


Instruction: When did the Medicines and Healt hcare product s Regulat ory Agency (MHRA) issue an aldost erone antagonist?

Output: Februar y 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Medicines and Healt hcare product s Regulat ory Agency (MHRA) issue an aldost erone antagonist?. ### Response: Februar y 2016.


Instruction: What agency published advice on concomitant use of spironolact one and r enin-angiot ensin syst em drugs in hear t failure concerning t he risk of potential f atal h yperkalaemia?

Output: Medicines and Healt hcare product s Regulat ory Agency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What agency published advice on concomitant use of spironolact one and r enin-angiot ensin syst em drugs in hear t failure concerning t he risk of potential f atal h yperkalaemia?. ### Response: Medicines and Healt hcare product s Regulat ory Agency.


Instruction: What is h yperkalaemia?

Output: risk of pot entially

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is h yperkalaemia?. ### Response: risk of pot entially.


Instruction: See t he MHRA advice f or mor e information?

Output: use of spironolact one and r enin-angiot ensin syst em drugs in hear t failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: See t he MHRA advice f or mor e information?. ### Response: use of spironolact one and r enin-angiot ensin syst em drugs in hear t failure.


Instruction: 1.5.5 Closely monit or the person's r enal function, electr olytes, hear t rate, blood pr essur e and o verall clinical status during what?

Output: tr eatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1.5.5 Closely monit or the person's r enal function, electr olytes, hear t rate, blood pr essur e and o verall clinical status during what?. ### Response: tr eatment.


Instruction: What do beta-blockers, aldost erone antagonists or angiot ensin-converting enzyme inhibit ors?

Output: angiot ensin-con verting enzyme inhibit or (or angiot ensin recept or block er if t here are intolerable side eff ects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do beta-blockers, aldost erone antagonists or angiot ensin-converting enzyme inhibit ors?. ### Response: angiot ensin-con verting enzyme inhibit or (or angiot ensin recept or block er if t here are intolerable side eff ects.


Instruction: What has been replaced by the NICE guideline on hear t valve disease?

Output: Valvular sur gery and per cutane ous intervention The r ecommendations on v alvular sur gery and per cutaneous int ervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been replaced by the NICE guideline on hear t valve disease?. ### Response: Valvular sur gery and per cutane ous intervention The r ecommendations on v alvular sur gery and per cutaneous int ervention.


Instruction: What is the NICE guideline on hear t valve disease?

Output: CG187

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NICE guideline on hear t valve disease?. ### Response: CG187.


Instruction: What should a specialist have a discussion with at an early stage?

Output: wit h a centr e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a specialist have a discussion with at an early stage?. ### Response: wit h a centr e.


Instruction: What is the title of the book Acut e hear t failure: diagnosis and management?

Output: CG187

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the book Acut e hear t failure: diagnosis and management?. ### Response: CG187.


Instruction: What year are all right s reserved?

Output: 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year are all right s reserved?. ### Response: 2022.


Instruction: What year was the last updat ed 17?

Output: 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the last updat ed 17?. ### Response: 2021.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the DOI: 10.1161/CIR.0000000000000923 February 2, 2021?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI: 10.1161/CIR.0000000000000923 February 2, 2021?. ### Response: Otto et al.


Instruction: What is a predictor of left ventricular function recovery after aortic valve replacement?

Output: Long term results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of left ventricular function recovery after aortic valve replacement?. ### Response: Long term results.


Instruction: What is the name of the study that looked at the long term results and predictors of left ventricle function recovery?

Output: Ann Thorac Cardiovasc Surg.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that looked at the long term results and predictors of left ventricle function recovery?. ### Response: Ann Thorac Cardiovasc Surg..


Instruction: In what year was the Ann Thorac Cardiovasc Surg published?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Ann Thorac Cardiovasc Surg published?. ### Response: 2015.


Instruction: What are outcomes in patients with aortic regurgitation and preserved left ventricular ejection fraction?

Output: Long-term outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are outcomes in patients with aortic regurgitation and preserved left ventricular ejection fraction?. ### Response: Long-term outcomes.


Instruction: What is the J Am Coll Cardiol. 2016:68:2144–53?

Output: Long-term outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2016:68:2144–53?. ### Response: Long-term outcomes.


Instruction: What are the names of the authors of the study?

Output: Cawley PJ, Hamilton-Craig C, Owens DS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the study?. ### Response: Cawley PJ, Hamilton-Craig C, Owens DS.


Instruction: What is the name of the journal in which the study was conducted?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal in which the study was conducted?. ### Response: J Am Coll Cardiol.


Instruction: How many patients with severe aortic regur -gitation are considered to have an outcome penalty?

Output: 18

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with severe aortic regur -gitation are considered to have an outcome penalty?. ### Response: 18.


Instruction: What is the stage of aortic regurgitation?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the stage of aortic regurgitation?. ### Response: B.


Instruction: What is a prospective comparison of cardiac magnetic resonance imaging and transthoracic echocardiography?

Output: valve regurgitation quantitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prospective comparison of cardiac magnetic resonance imaging and transthoracic echocardiography?. ### Response: valve regurgitation quantitation.


Instruction: Who is Cranney GB?

Output: 21

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Cranney GB?. ### Response: 21.


Instruction: What is the name of the imaging method used to measure left ventricular volume?

Output: cardiac axis nuclear magnetic resonance imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the imaging method used to measure left ventricular volume?. ### Response: cardiac axis nuclear magnetic resonance imaging.


Instruction: What is used to validate ventricular angiography?

Output: cardiac axis nuclear magnetic resonance imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to validate ventricular angiography?. ### Response: cardiac axis nuclear magnetic resonance imaging.


Instruction: When was Circulation published?

Output: 1990

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation published?. ### Response: 1990.


Instruction: What is a possible outcome of aortic regurgitation?

Output: clinical

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible outcome of aortic regurgitation?. ### Response: clinical.


Instruction: What is the name of the technique used to assess the severity of mitral re-gurgitation as assessed by cardiovascular magnetic resonance?

Output: Doppler echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the technique used to assess the severity of mitral re-gurgitation as assessed by cardiovascular magnetic resonance?. ### Response: Doppler echocardiography.


Instruction: How does Doppler echocardiography compare to other imaging methods?

Output: optimizing correlation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Doppler echocardiography compare to other imaging methods?. ### Response: optimizing correlation.