Instruction: Patients decide Healthcare professionals felt what?

Output: 'competent' ICD recipients  should decide whether to deactivate  their device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients decide Healthcare professionals felt what?. ### Response: 'competent' ICD recipients  should decide whether to deactivate  their device.


Instruction: Who felt competent ICD recipients should decide whether to deactivate their device?

Output: Healthcare professionals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who felt competent ICD recipients should decide whether to deactivate their device?. ### Response: Healthcare professionals.


Instruction: What did Healthcare professionals highlight the importance of?

Output: discussions with the person  and family

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Healthcare professionals highlight the importance of?. ### Response: discussions with the person  and family.


Instruction: What should have an end of life discussion?

Output: iologists considering  implanting a device

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should have an end of life discussion?. ### Response: iologists considering  implanting a device.


Instruction: Patients reported that the frequency and pain of shocks, overall quality of life and recommendations of the physician could impact their decision?

Output: deactivation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients reported that the frequency and pain of shocks, overall quality of life and recommendations of the physician could impact their decision?. ### Response: deactivation.


Instruction: Nurses felt that families sometimes put pressure on patients to get a device or to what?

Output: keep a device active

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nurses felt that families sometimes put pressure on patients to get a device or to what?. ### Response: keep a device active.


Instruction: What type of patients are put pressure on to get a device?

Output: families

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients are put pressure on to get a device?. ### Response: families.


Instruction: What are some concerns about the coherence of the studies contributing to this sub-finding?

Output: minor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some concerns about the coherence of the studies contributing to this sub-finding?. ### Response: minor.


Instruction: Why was there a lack of depth in the evidence?

Output: moderate  concerns about inadequacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there a lack of depth in the evidence?. ### Response: moderate  concerns about inadequacy.


Instruction: What was the overall judgement of the study?

Output: moderate  confidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall judgement of the study?. ### Response: moderate  confidence.


Instruction: What is the overall judgement of low confidence in this sub-finding?

Output: very low  confidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the overall judgement of low confidence in this sub-finding?. ### Response: very low  confidence.


Instruction: What are concerns regarding methodological limitations, relevance and adequacy?

Output: very low  confidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are concerns regarding methodological limitations, relevance and adequacy?. ### Response: very low  confidence.


Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3827 742.

Output: 757–764

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Meschia et al Guidelines for the Primary Prevention of Stroke 3827 742.. ### Response: 757–764.


Instruction: What does Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea?

Output: results of a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea?. ### Response: results of a meta-analysis.


Instruction: Sleep. 2004;27:249–253.

Output: 743

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sleep. 2004;27:249–253.. ### Response: 743.


Instruction: What is obstructive sleep apnea?

Output: Effect of nocturnal nasal con-tinuous positive airway pressure on blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is obstructive sleep apnea?. ### Response: Effect of nocturnal nasal con-tinuous positive airway pressure on blood pressure.


Instruction: What is the use of auto-titrating continuous positive airway pressure for?

Output: treatment of adult obstructive sleep apnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use of auto-titrating continuous positive airway pressure for?. ### Response: treatment of adult obstructive sleep apnea.


Instruction: What is the Cochrane Database Syst Rev. 2004:CD003531?

Output: Interventions to improve compliance with continuous positive airway pressure for obstructive sleep apnoea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Cochrane Database Syst Rev. 2004:CD003531?. ### Response: Interventions to improve compliance with continuous positive airway pressure for obstructive sleep apnoea.


Instruction: What is a treatment for obstructive sleep apnea?

Output: Positive airway pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a treatment for obstructive sleep apnea?. ### Response: Positive airway pressure.


Instruction: What did Smith I and Lasserson TJ use to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea?

Output: Educational, supportive and behavioural interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Smith I and Lasserson TJ use to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea?. ### Response: Educational, supportive and behavioural interventions.


Instruction: What did Cochrane Database Syst Rev. 2009:CD003531?

Output: Pressure modification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database Syst Rev. 2009:CD003531. 747

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Cochrane Database Syst Rev. 2009:CD003531?. ### Response: Pressure modification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database Syst Rev. 2009:CD003531. 747.


Instruction: What are interventions to improve usage of for adults with obstructive sleep apnoea?

Output: continuous positive airway pressure machines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are interventions to improve usage of for adults with obstructive sleep apnoea?. ### Response: continuous positive airway pressure machines.


Instruction: Cochrane Database Syst Rev. 2009:CD007736. 748.

Output: obstructive sleep apnoea. Cochrane Database Syst Rev. 2009:CD003531. 747. Smith I, Nadig V , Lasserson TJ. Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines for adults with obstructive sleep apnoea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cochrane Database Syst Rev. 2009:CD007736. 748.. ### Response: obstructive sleep apnoea. Cochrane Database Syst Rev. 2009:CD003531. 747. Smith I, Nadig V , Lasserson TJ. Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines for adults with obstructive sleep apnoea.


Instruction: What is long-term use of CPAP therapy for?

Output: sleep apnea/hypopnea syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is long-term use of CPAP therapy for?. ### Response: sleep apnea/hypopnea syndrome.


Instruction: What is a risk factor for sleep apnea?

Output: nocturnal nasal con-tinuous positive airway pressure on blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for sleep apnea?. ### Response: nocturnal nasal con-tinuous positive airway pressure on blood pressure.


Instruction: What is the name of the study that examined the association between sleep-disordered breathing and hypertension?

Output: Prospective study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the association between sleep-disordered breathing and hypertension?. ### Response: Prospective study.


Instruction: What is obstructive sleep apnoea syn-drome as a risk factor for hypertension?

Output: population study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is obstructive sleep apnoea syn-drome as a risk factor for hypertension?. ### Response: population study.


Instruction: BMJ. 2000;320:479–482.

Output: 751

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BMJ. 2000;320:479–482.. ### Response: 751.


Instruction: Logan AG, Perlikowski SM, Mente A, Tisler A, Tkacova R, Niroumand M, Leung RS, Bradley TD. High prevalence of what in drug-resistant hypertension.

Output: unrecognized sleep apnoea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Logan AG, Perlikowski SM, Mente A, Tisler A, Tkacova R, Niroumand M, Leung RS, Bradley TD. High prevalence of what in drug-resistant hypertension.. ### Response: unrecognized sleep apnoea.


Instruction: J Hypertens 2001;19:2271–2277.

Output: 752

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Hypertens 2001;19:2271–2277.. ### Response: 752.


Instruction: What is the effect of nocturnal nasal con-tinuous positive airway pressure on blood pressure in obstructive sleep apnea?

Output: 417–423. 753

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of nocturnal nasal con-tinuous positive airway pressure on blood pressure in obstructive sleep apnea?. ### Response: 417–423. 753.


Instruction: What is the effect of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syn-drome?

Output: evidence from a meta-analysis of placebo-controlled randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syn-drome?. ### Response: evidence from a meta-analysis of placebo-controlled randomized trials.


Instruction: What did De Weerdt S, Poppe K, Dupont A, Velkeniers B?

Output: Meerhaeghe A, Moscariello A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did De Weerdt S, Poppe K, Dupont A, Velkeniers B?. ### Response: Meerhaeghe A, Moscariello A.


Instruction: What is the effect of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopneua?

Output: improve compliance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopneua?. ### Response: improve compliance.


Instruction: What is a meta-analysis of randomized controlled trials?

Output: Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of randomized controlled trials?. ### Response: Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopnea.


Instruction: What is the name of the study that examined sleep disorders and sleep deprivation?

Output: An Unmet Public Health Problem

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined sleep disorders and sleep deprivation?. ### Response: An Unmet Public Health Problem.


Instruction: What was the title of this study?

Output: meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of this study?. ### Response: meta-analysis.


Instruction: What year did the guideline committee make t he following r ecommendations f or resear ch?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the guideline committee make t he following r ecommendations f or resear ch?. ### Response: 2010.


Instruction: What is detailed in the full guideline?

Output: full set of r ecommendations f or resear ch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is detailed in the full guideline?. ### Response: full set of r ecommendations f or resear ch.


Instruction: Cost -effectiveness of multislic e CT?

Output: highly sensitiv e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cost -effectiveness of multislic e CT?. ### Response: highly sensitiv e.


Instruction: What is a cost -effectiveness o f multislic e CT c oronar y angiography for ruling ou t obstructive coronary artery dise ase in pe ople wi th tr oponin -negative acute coronary syndr omes?

Output: cost eff ectiv e compar ed with exercise ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cost -effectiveness o f multislic e CT c oronar y angiography for ruling ou t obstructive coronary artery dise ase in pe ople wi th tr oponin -negative acute coronary syndr omes?. ### Response: cost eff ectiv e compar ed with exercise ECG.


Instruction: What is CAD?

Output: cor onar y artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CAD?. ### Response: cor onar y artery disease.


Instruction: What type of CT is used to rule out CAD in people with suspected ed tr oponin-negativ?

Output: Multislice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of CT is used to rule out CAD in people with suspected ed tr oponin-negativ?. ### Response: Multislice.


Instruction: What does the Eur opean Society of Car diology guidelines state in tr oponin-negativ e ACS with no ST -segment change on the ECG?

Output: 'a str ess t est is r ecommended… in patient s wit h significant ischaemia during t he str ess t est, cor onar y angiograph y and subsequent revascularisation should be consider ed'.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Eur opean Society of Car diology guidelines state in tr oponin-negativ e ACS with no ST -segment change on the ECG?. ### Response: 'a str ess t est is r ecommended… in patient s wit h significant ischaemia during t he str ess t est, cor onar y angiograph y and subsequent revascularisation should be consider ed'..


Instruction: What is r ecommended in patient s wit h significant ischaemia during t he str ess?

Output: a str ess t est

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is r ecommended in patient s wit h significant ischaemia during t he str ess?. ### Response: a str ess t est.


Instruction: What should be considered for a patient with significant ischaemia during str ess t est?

Output: cor onar y angiograph y and subsequent revascularisation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered for a patient with significant ischaemia during str ess t est?. ### Response: cor onar y angiograph y and subsequent revascularisation.


Instruction: What is the sensitivity and specificity of CAD in t he gr op of people?

Output: diagnosing CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sensitivity and specificity of CAD in t he gr op of people?. ### Response: diagnosing CAD.


Instruction: What is one way to diagnose CAD in t his gr oup of people?

Output: sensitivity and specificity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one way to diagnose CAD in t his gr oup of people?. ### Response: sensitivity and specificity.


Instruction: What is an unnecessarily invasive cor onar y angiogram?

Output: normal cor onar y arteries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an unnecessarily invasive cor onar y angiogram?. ### Response: normal cor onar y arteries.


Instruction: What is invasive cor onar y angiogram?

Output: normal cor onar y arteries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is invasive cor onar y angiogram?. ### Response: normal cor onar y arteries.


Instruction: What is highly sensitiv e and pr ovides a potentially useful means f or early rule-out of CAD in tr oponin-negativ?

Output: Multislice CT cor onar y angiograph

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is highly sensitiv e and pr ovides a potentially useful means f or early rule-out of CAD in tr oponin-negativ?. ### Response: Multislice CT cor onar y angiograph.


Instruction: What should be used as a first step in diagnosing a disease?

Output: exercise ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used as a first step in diagnosing a disease?. ### Response: exercise ECG.


Instruction: What is a telep hone ad vice used for?

Output: chest pain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a telep hone ad vice used for?. ### Response: chest pain.


Instruction: What should t elephone advice be giv en to people calling wit h chest pain?

Output: cir cumstances

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should t elephone advice be giv en to people calling wit h chest pain?. ### Response: cir cumstances.


Instruction: Is the appr opriat eness influenced by age, se x or sympt oms?

Output: sensitivity and specificity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is the appr opriat eness influenced by age, se x or sympt oms?. ### Response: sensitivity and specificity.


Instruction: Recent onset chest pain of what type?

Output: suspect ed car diac origin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recent onset chest pain of what type?. ### Response: suspect ed car diac origin.


Instruction: What is the name of the book that describes recent onset chest pain of suspect ed car diac origin?

Output: CG95

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that describes recent onset chest pain of suspect ed car diac origin?. ### Response: CG95.


Instruction: When will all right s reserved?

Output: 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will all right s reserved?. ### Response: 2022.


Instruction: People have the right to be in volved in discussions and make informed decisions about what?

Output: t heir car e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People have the right to be in volved in discussions and make informed decisions about what?. ### Response: t heir car e.


Instruction: NICE's inf ormation on making decisions about our care describes what right?

Output: the right t o be in volved in discussions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: NICE's inf ormation on making decisions about our care describes what right?. ### Response: the right t o be in volved in discussions.


Instruction: Making decisions using NICE guidelines explains ho w we use how?

Output: w ords

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Making decisions using NICE guidelines explains ho w we use how?. ### Response: w ords.


Instruction: What does NICE explain about prescribing medicines?

Output: off -label use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NICE explain about prescribing medicines?. ### Response: off -label use.


Instruction: What are standar ds and laws?

Output: including on consent and mental capacity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are standar ds and laws?. ### Response: including on consent and mental capacity.


Instruction: Laws on consent and mental capacity are examples of what?

Output: standar ds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Laws on consent and mental capacity are examples of what?. ### Response: standar ds.


Instruction: What should the cor e specialist hear t failure multidisciplinar y team work in collaboration with?

Output: primar y car e team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the cor e specialist hear t failure multidisciplinar y team work in collaboration with?. ### Response: primar y car e team.


Instruction: What is a lead ph ysician wit h subspecialty training in hear t failure?

Output: consultant cardiologist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a lead ph ysician wit h subspecialty training in hear t failure?. ### Response: consultant cardiologist.


Instruction: A consultant cardiologist is r esponsible f or making what clinical diagnosis?

Output: decompensat ed or adv anced hear t failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A consultant cardiologist is r esponsible f or making what clinical diagnosis?. ### Response: decompensat ed or adv anced hear t failure.


Instruction: What should a specialist hear t failure nurse do?

Output: making t he clinical diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a specialist hear t failure nurse do?. ### Response: making t he clinical diagnosis.


Instruction: What should the specialist hear failure MD do to people newly diagnosed?

Output: give information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the specialist hear failure MD do to people newly diagnosed?. ### Response: give information.


Instruction: Who should give information t o newly diagnosed people?

Output: The specialist hear t failure MD T

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should give information t o newly diagnosed people?. ### Response: The specialist hear t failure MD T.


Instruction: How do people newly diagnosed wit h hear t failure do?

Output: give information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do people newly diagnosed wit h hear t failure do?. ### Response: give information.


Instruction: How do newly diagnosed people manage newly diagnosed, r ecently decompensat ed or advanced hearing failure?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do newly diagnosed people manage newly diagnosed, r ecently decompensat ed or advanced hearing failure?. ### Response: •.


Instruction: What is the New York Hear t Association's class III t o IV?

Output: NYHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the New York Hear t Association's class III t o IV?. ### Response: NYHA.


Instruction: How is Chronic hear t failure in adult s diagnosed and managed?

Output: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is Chronic hear t failure in adult s diagnosed and managed?. ### Response: diagnosis and management.


Instruction: What is NICE 2023?

Output: All right s reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2023?. ### Response: All right s reserved.


Instruction: What is a Notice of right s?

Output: be in volved in discussions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Notice of right s?. ### Response: be in volved in discussions.


Instruction: How many pages are on the Notice of Right s page?

Output: 6 of36

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages are on the Notice of Right s page?. ### Response: 6 of36.


Instruction: What is the name of the website that provides notice of rights?

Output: https://www .nice.or g.uk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the website that provides notice of rights?. ### Response: https://www .nice.or g.uk.


Instruction: How many plasma samples were taken from unfractionated heparin-treated patients in 2000?

Output: 2,773

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many plasma samples were taken from unfractionated heparin-treated patients in 2000?. ### Response: 2,773.


Instruction: How many plasma samples were taken from unfractionated heparin-treated patients in 1997?

Output: 2,773

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many plasma samples were taken from unfractionated heparin-treated patients in 1997?. ### Response: 2,773.


Instruction: What is an institution-specifi c therapeutic range for heparin?

Output: adjusted-dose unfractionated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an institution-specifi c therapeutic range for heparin?. ### Response: adjusted-dose unfractionated.


Instruction: What year was the Am J Health Syst Pharm published?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the Am J Health Syst Pharm published?. ### Response: 1998.


Instruction: How many ( 19 ): 2002 - 2006?

Output: 55

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 19 ): 2002 - 2006?. ### Response: 55.


Instruction: What was the total number of drugs used from 1998 to 2006 in the United States?

Output: 82

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the total number of drugs used from 1998 to 2006 in the United States?. ### Response: 82.


Instruction: Anticoagulants and thrombolytics are two examples of what type of drugs?

Output: Toxic effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anticoagulants and thrombolytics are two examples of what type of drugs?. ### Response: Toxic effects.


Instruction: What is a risk and benefi ts of drugs used in the ICU?

Output: Toxic effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk and benefi ts of drugs used in the ICU?. ### Response: Toxic effects.


Instruction: Crit Care Clin. 1991; 7 ( 3 ): 533 - 554: what?

Output: heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Crit Care Clin. 1991; 7 ( 3 ): 533 - 554: what?. ### Response: heparin.


Instruction: What is the name of the heparin assays based on ex-vivo samples?

Output: Thromb Haemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the heparin assays based on ex-vivo samples?. ### Response: Thromb Haemost.


Instruction: What was the time of the activated partial thromboplastin?

Output: 1991 ; 7 ( 3 ): 533 - 554

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the time of the activated partial thromboplastin?. ### Response: 1991 ; 7 ( 3 ): 533 - 554.


Instruction: What are heparin assays based on?

Output: ex-vivo heparin samples

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are heparin assays based on?. ### Response: ex-vivo heparin samples.


Instruction: How many ( 1 ): 16-23?

Output: 63

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 1 ): 16-23?. ### Response: 63.


Instruction: What did the Quality Management Program of Ontario coagula-tion surveys learn from?

Output: Interlaboratory variation in heparin monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Quality Management Program of Ontario coagula-tion surveys learn from?. ### Response: Interlaboratory variation in heparin monitoring.


Instruction: What was the number of Thromb Haemost cases in 2010?

Output: 837 - 844

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the number of Thromb Haemost cases in 2010?. ### Response: 837 - 844.


Instruction: How many Thromb Haemost cases were there in 2010?

Output: 837 - 844

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Thromb Haemost cases were there in 2010?. ### Response: 837 - 844.


Instruction: What was the total number of cases of thrombus haemost?

Output: 16 - 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the total number of cases of thrombus haemost?. ### Response: 16 - 23.


Instruction: What is a standard heparin nomogram for the management of hep-arin therapy?

Output: Arch Intern Med

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a standard heparin nomogram for the management of hep-arin therapy?. ### Response: Arch Intern Med.


Instruction: What is the 151 ( 2 ): 333 - 337?

Output: A standard heparin nomogram

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 151 ( 2 ): 333 - 337?. ### Response: A standard heparin nomogram.


Instruction: What is the difference between subcutaneous adjusted-dose unfractionated heparin vs fixed-dose low-molecular-weight Heparin in the initial treatment of venous vein?

Output: ﬁ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between subcutaneous adjusted-dose unfractionated heparin vs fixed-dose low-molecular-weight Heparin in the initial treatment of venous vein?. ### Response: ﬁ.


Instruction: What does xed-dose low-molecular-weight heparin do?

Output: initial treatment of venous thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does xed-dose low-molecular-weight heparin do?. ### Response: initial treatment of venous thromboembolism.


Instruction: What is used in the initial treatment of venous thromboembolism?

Output: Subcutaneous adjusted-dose unfractionated heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used in the initial treatment of venous thromboembolism?. ### Response: Subcutaneous adjusted-dose unfractionated heparin.


Instruction: How many ( 10 ): 1077-1083?

Output: 164

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 10 ): 1077-1083?. ### Response: 164.


Instruction: What are the ACC/AHA Guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction?

Output: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the ACC/AHA Guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction?. ### Response: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: 1999 update:  ACC/AHA guidelines for the management of patients with acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: 1999 update:  ACC/AHA guidelines for the management of patients with acute myocardial infarction.


Instruction: What is the name of the Task Force on Practice Guidelines?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Practice Guidelines?. ### Response: American College of Cardiology/American Heart Association.


Instruction: When was the J Am Coll Cardiol 36 (3): 970-1062?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 36 (3): 970-1062?. ### Response: 2000.


Instruction: What are the ACC/AHA guidelines for the management of patients with acute myocardial infarction?

Output: unstable angina and non-ST-segment elevation myocardial infarction .  A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the ACC/AHA guidelines for the management of patients with acute myocardial infarction?. ### Response: unstable angina and non-ST-segment elevation myocardial infarction .  A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: Task Force on Practice Guidelines. 1999 ; 34 (3): 890 - 911.

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Task Force on Practice Guidelines. 1999 ; 34 (3): 890 - 911.. ### Response: J Am Coll Cardiol.


Instruction: Who wrote Heparin: Chemical and Biological Properties, Clinical Applications?

Output: Land DA, Lindahl U, eds.  Heparin: Chemical and Biological Properties, Clinical Applications  .  London, England :  Edward Arnold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote Heparin: Chemical and Biological Properties, Clinical Applications?. ### Response: Land DA, Lindahl U, eds.  Heparin: Chemical and Biological Properties, Clinical Applications  .  London, England :  Edward Arnold.


Instruction: Where did Land DA and Lindahl U live?

Output: London, England

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did Land DA and Lindahl U live?. ### Response: London, England.


Instruction: What is Morabia A referring to?

Output: Heparin doses and major bleedings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Morabia A referring to?. ### Response: Heparin doses and major bleedings.


Instruction: What is the name of the journal that published a study on Heparin doses and bleedings?

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published a study on Heparin doses and bleedings?. ### Response: Lancet.


Instruction: 57. Antman EM. the TIMI 9A Investigators?

Output: Hirudin in acute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 57. Antman EM. the TIMI 9A Investigators?. ### Response: Hirudin in acute.


Instruction: Hirudin in acute acute pain?

Output: heparin vs ﬁ  xed-dose low-molecular-weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hirudin in acute acute pain?. ### Response: heparin vs ﬁ  xed-dose low-molecular-weight heparin.


Instruction: What is VA/DoD CPG f or the Management of Dyslipidemia for Cardiovascular Risk Reduction?

Output: Provider Summary  June 2020  Page 5 of 11 Algorithm  This CPG ’s algorithm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is VA/DoD CPG f or the Management of Dyslipidemia for Cardiovascular Risk Reduction?. ### Response: Provider Summary  June 2020  Page 5 of 11 Algorithm  This CPG ’s algorithm.


Instruction: What is the algorithm designed to facilitate understanding of the clinical pathway and decision making process used in identifying patients at risk for CVD?

Output: step -by-step decision tree

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the algorithm designed to facilitate understanding of the clinical pathway and decision making process used in identifying patients at risk for CVD?. ### Response: step -by-step decision tree.


Instruction: What is the process used in identifying patients at risk for CVD?

Output: decision -making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the process used in identifying patients at risk for CVD?. ### Response: decision -making.


Instruction: What is a simplified flow of the management of patients with dyslipidemia?

Output: algorithm format

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simplified flow of the management of patients with dyslipidemia?. ### Response: algorithm format.


Instruction: What is the algorithm called?

Output: a step -by-step decision tree

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the algorithm called?. ### Response: a step -by-step decision tree.


Instruction: What symbols are used to display each step?

Output: Standardized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What symbols are used to display each step?. ### Response: Standardized.


Instruction: Arrows connect the numbered boxes indicating the order in which the steps should be followed?

Output: Standardized symbols are used to display each step

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arrows connect the numbered boxes indicating the order in which the steps should be followed?. ### Response: Standardized symbols are used to display each step.


Instruction: What provide more detailed information to assist in defining and interpreting elements in the boxes?

Output: Sidebars

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What provide more detailed information to assist in defining and interpreting elements in the boxes?. ### Response: Sidebars.


Instruction: What represent a decision point in the guideline, formulated as a question that can be answered “Yes” or “No”?

Output: Hexagons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What represent a decision point in the guideline, formulated as a question that can be answered “Yes” or “No”?. ### Response: Hexagons.


Instruction: Rectangles represent an action in what process of care?

Output: care  Ovals represent a link to another section within the guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Rectangles represent an action in what process of care?. ### Response: care  Ovals represent a link to another section within the guideline.


Instruction: In the process of care what represent a link to another section within the guideline?

Output: Ovals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the process of care what represent a link to another section within the guideline?. ### Response: Ovals.


Instruction: What is IV alteplase recommended for?

Output: patients who can be treated within 3 hours of ischemic stroke symptom onset or patient last known well or at baseline state

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is IV alteplase recommended for?. ### Response: patients who can be treated within 3 hours of ischemic stroke symptom onset or patient last known well or at baseline state.


Instruction: How long after ischemic stroke symptom onset or patient last known well?

Output: 3 and 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after ischemic stroke symptom onset or patient last known well?. ### Response: 3 and 4.5 hours.


Instruction: What is the name of the online data supplement?

Output: 1.3.5.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the online data supplement?. ### Response: 1.3.5.2.


Instruction: What was revised from 2015 IV Alteplase?

Output: B-RRecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was revised from 2015 IV Alteplase?. ### Response: B-RRecommendation.


Instruction: COR and LOE were added to conform with what system?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: COR and LOE were added to conform with what system?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: What may be reasonable for patients with mild disabling stroke symptoms?

Output: IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable for patients with mild disabling stroke symptoms?. ### Response: IV alteplase.


Instruction: How long after ischemic stroke symptom onset can IV alteplase be used?

Output: 3 and 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after ischemic stroke symptom onset can IV alteplase be used?. ### Response: 3 and 4.5 hours.


Instruction: What is the recommendation of the IIb B-NRNew?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommendation of the IIb B-NRNew?. ### Response: 3.


Instruction: For patients with mild nondisabling stroke symptoms (NIHSS score 0-5), what may be reasonable?

Output: IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For patients with mild nondisabling stroke symptoms (NIHSS score 0-5), what may be reasonable?. ### Response: IV alteplase.


Instruction: What is not recommended for patients who could be treated within 3 hours of ischemic stroke symptom onset or patient last known well or at baseline state?

Output: IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for patients who could be treated within 3 hours of ischemic stroke symptom onset or patient last known well or at baseline state?. ### Response: IV alteplase.


Instruction: For otherwise eligible patients with mild non-disabling stroke symptoms (NIHSS score 0-5), what is IV alteplase not recommended?

Output: could be treated within 3 and 4.5 hours of ischemic stroke symptom onset or patient last known well or at baseline state

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For otherwise eligible patients with mild non-disabling stroke symptoms (NIHSS score 0-5), what is IV alteplase not recommended?. ### Response: could be treated within 3 and 4.5 hours of ischemic stroke symptom onset or patient last known well or at baseline state.


Instruction: What is not recommended for patients who could be treated within 3 and 4.5 hours of ischemic stroke symptom onset or patient last known well or at baseline state?

Output: IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for patients who could be treated within 3 and 4.5 hours of ischemic stroke symptom onset or patient last known well or at baseline state?. ### Response: IV alteplase.


Instruction: What has inconsistently shown a benefit for IV alteplase?

Output: Subgroup analyses of the NINDS rt-PA Trial and IST (International Stroke Trial)-3 with mild stroke defined in various ways

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has inconsistently shown a benefit for IV alteplase?. ### Response: Subgroup analyses of the NINDS rt-PA Trial and IST (International Stroke Trial)-3 with mild stroke defined in various ways.


Instruction: What did a meta-analysis of 9 trials show?

Output: benefit for patients with mild stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a meta-analysis of 9 trials show?. ### Response: benefit for patients with mild stroke.


Instruction: How many trials included subjects from the NINDS rt-PA trial?

Output: 9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many trials included subjects from the NINDS rt-PA trial?. ### Response: 9.


Instruction: What did the NINDS rt-PA trial and IST-3 show for patients with mild stroke?

Output: benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the NINDS rt-PA trial and IST-3 show for patients with mild stroke?. ### Response: benefit.


Instruction: What was the NIHSS score 0 to 4.164?

Output: benefit for patients with mild stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the NIHSS score 0 to 4.164?. ### Response: benefit for patients with mild stroke.


Instruction: In ECASS III, there was no significant interaction of benefit or safety with what?

Output: stroke severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In ECASS III, there was no significant interaction of benefit or safety with what?. ### Response: stroke severity.


Instruction: What was the baseline NIHSS score of patients with stroke severity?

Output: 0 to 9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the baseline NIHSS score of patients with stroke severity?. ### Response: 0 to 9.


Instruction: What is SITS-ISTR?

Output: Safe Implementation of Treatments in Stroke–International Stroke Thrombolysis Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SITS-ISTR?. ### Response: Safe Implementation of Treatments in Stroke–International Stroke Thrombolysis Registry.


Instruction: How was the mRS score at 90 days?

Output: 0–1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the mRS score at 90 days?. ### Response: 0–1.


Instruction: When was the risk of sICH similar or different?

Output: same

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the risk of sICH similar or different?. ### Response: same.


Instruction: How long did it take for a stroke to develop sICH?

Output: 0 to 3 and 3 to 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for a stroke to develop sICH?. ### Response: 0 to 3 and 3 to 4.5 hours.


Instruction: What was the duration of a mild stroke treated?

Output: 0 to 3 and 3 to 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the duration of a mild stroke treated?. ### Response: 0 to 3 and 3 to 4.5 hours.


Instruction: How long was it for mild stroke to get a good functional outcome and mortality?

Output: 0 to 3 and 3 to 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was it for mild stroke to get a good functional outcome and mortality?. ### Response: 0 to 3 and 3 to 4.5 hours.


Instruction: How long were patients with mild stroke treated?

Output: 0 to 3 and 3 to 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long were patients with mild stroke treated?. ### Response: 0 to 3 and 3 to 4.5 hours.


Instruction: What was not further categorized by whether their acute neurological deficits were disabling?

Output: These patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not further categorized by whether their acute neurological deficits were disabling?. ### Response: These patients.


Instruction: The PRISMS RCT evaluated what?

Output: IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The PRISMS RCT evaluated what?. ### Response: IV alteplase.


Instruction: Activase evaluated IV alteplase in patients with what type of stroke?

Output: Mild

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Activase evaluated IV alteplase in patients with what type of stroke?. ### Response: Mild.


Instruction: What was not interfered with activities of daily living or prevent return to work?

Output: acute neurological deficits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not interfered with activities of daily living or prevent return to work?. ### Response: acute neurological deficits.


Instruction: How long does it take for a patient to receive treatment?

Output: 3 and 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a patient to receive treatment?. ### Response: 3 and 4.5 hours.


Instruction: When will the data be available for download?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the data be available for download?. ### Response: April 28, 2023.


Instruction: What was considered a measure to assess use of a standardized protocol for antiplatelet and anticoagulation therapy?

Output: the writing committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered a measure to assess use of a standardized protocol for antiplatelet and anticoagulation therapy?. ### Response: the writing committee.


Instruction: What is there scant evidence to link their use of?

Output: a protocol to improved patient outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there scant evidence to link their use of?. ### Response: a protocol to improved patient outcomes.


Instruction: What is there scant evidence to link their use of a protocol to?

Output: improved patient outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there scant evidence to link their use of a protocol to?. ### Response: improved patient outcomes.


Instruction: Dosing guidelines exist for specific agents?

Output: antiplatelet and anticoagulation therapy, the writing committee considered a measure to assess use of a standardized protocol for these agents. However, despite their extensive use of these protocols, there is scant evidence to link their use of a protocol to improved patient outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Dosing guidelines exist for specific agents?. ### Response: antiplatelet and anticoagulation therapy, the writing committee considered a measure to assess use of a standardized protocol for these agents. However, despite their extensive use of these protocols, there is scant evidence to link their use of a protocol to improved patient outcomes.


Instruction: There is a wide range of variability even in what guidelines?

Output: Dosing guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is a wide range of variability even in what guidelines?. ### Response: Dosing guidelines.


Instruction: What did the writing committee decide the measure offered little added value to?

Output: quality care assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing committee decide the measure offered little added value to?. ### Response: quality care assessment.


Instruction: What was the complexity required for its effective implementation?

Output: quality care assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the complexity required for its effective implementation?. ### Response: quality care assessment.


Instruction: The writing committee does encourage development and implementation of what?

Output: protocols for antiplatelet and anticoagulant therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The writing committee does encourage development and implementation of what?. ### Response: protocols for antiplatelet and anticoagulant therapy.


Instruction: What does the writing committee encourage development and implementation of?

Output: protocols for antiplatelet and anticoagulant therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing committee encourage development and implementation of?. ### Response: protocols for antiplatelet and anticoagulant therapy.


Instruction: What might occur in future iterations of this measure set as the evidence base evolves?

Output: reconsideration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might occur in future iterations of this measure set as the evidence base evolves?. ### Response: reconsideration.


Instruction: What did the writing committee consider using for managing contrast-related nephropathy before and during?

Output: a protocol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing committee consider using for managing contrast-related nephropathy before and during?. ### Response: a protocol.


Instruction: When was the draft published?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the draft published?. ### Response: May 3, 2023.


Instruction: What would not require follow-up LDL-C measurements because the results would not alter?

Output: receiving a statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would not require follow-up LDL-C measurements because the results would not alter?. ### Response: receiving a statin.


Instruction: What is less robust in people with CKD?

Output: the link between LDL-C andadverse clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less robust in people with CKD?. ### Response: the link between LDL-C andadverse clinical outcomes.


Instruction: What is the value of measuringLDL-C to assess prognosis?

Output: unclear

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the value of measuringLDL-C to assess prognosis?. ### Response: unclear.


Instruction: There is no direct evidence that following on-treatmentlipid levels will improve clinical outcomes or encourageadherence to what?

Output: statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no direct evidence that following on-treatmentlipid levels will improve clinical outcomes or encourageadherence to what?. ### Response: statin therapy.


Instruction: What may some patients prefer to know during follow-up?

Output: lipid levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may some patients prefer to know during follow-up?. ### Response: lipid levels.


Instruction: What may patients increase their adherence to statin treatment in response to feedback about their lipid levels?

Output: some patients mayprefer to know their lipid levels during follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may patients increase their adherence to statin treatment in response to feedback about their lipid levels?. ### Response: some patients mayprefer to know their lipid levels during follow-up.


Instruction: What type of treatment is recommended for adults with CKD and eGFR X60 ml/min per 1.73 m2(GFRcategories G3a-G5)?

Output: simvastatin/ezetimibe combination therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of treatment is recommended for adults with CKD and eGFR X60 ml/min per 1.73 m2(GFRcategories G3a-G5)?. ### Response: simvastatin/ezetimibe combination therapy.


Instruction: What type ostatin orezetimibe combination is recommended?

Output: simvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type ostatin orezetimibe combination is recommended?. ### Response: simvastatin.


Instruction: What is the recommended treatment for adults with CKD?

Output: as t a t i n2A 2.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recommended treatment for adults with CKD?. ### Response: as t a t i n2A 2.2.


Instruction: What does statin do in people with kidney transplantation or dialysis?

Output: reduce the relative risk ofcardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does statin do in people with kidney transplantation or dialysis?. ### Response: reduce the relative risk ofcardiovascular events.


Instruction: What is statin used for in people with known coronary disease or revascularization?

Output: reduces the risk of major atherosclerotic events (coronarydeath, MI, non-hemorrhagic stroke, or any revascularization)compared with placebo in people with GFR categoriesG3a–G5.22These data are supported by post hoc analyses ofrandomized trials of statin versus placebo that focus on thesubset of participants with CKD at baseline. In general, theseanalyses suggest that statins reduce the relative risk ofcardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is statin used for in people with known coronary disease or revascularization?. ### Response: reduces the risk of major atherosclerotic events (coronarydeath, MI, non-hemorrhagic stroke, or any revascularization)compared with placebo in people with GFR categoriesG3a–G5.22These data are supported by post hoc analyses ofrandomized trials of statin versus placebo that focus on thesubset of participants with CKD at baseline. In general, theseanalyses suggest that statins reduce the relative risk ofcardiovascular events.


Instruction: What is the incidence of coronary death or non-fatalmyocardial infarction?

Output: 410%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incidence of coronary death or non-fatalmyocardial infarction?. ### Response: 410%.


Instruction: SHARP STUDY HAD A LARGE IMPACT ON WHAT?

Output: A STRONGR E C O M M E N D A T I O NI NG F RC A T E G O R I E SG 3 A – G 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: SHARP STUDY HAD A LARGE IMPACT ON WHAT?. ### Response: A STRONGR E C O M M E N D A T I O NI NG F RC A T E G O R I E SG 3 A – G 5.


Instruction: What is the absolute risk of future coronary events in people with non-dialysis-dependent CKD?

Output: 410 per 1000 patient-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the absolute risk of future coronary events in people with non-dialysis-dependent CKD?. ### Response: 410 per 1000 patient-years.


Instruction: What is not required togauge average coronary risk in people with non-dialysis-dependent CKD?

Output: knowledge of LDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not required togauge average coronary risk in people with non-dialysis-dependent CKD?. ### Response: knowledge of LDL-C.


Instruction: What might yield more preciseestimates of risk for individuals?

Output: multivariate prediction instruments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might yield more preciseestimates of risk for individuals?. ### Response: multivariate prediction instruments.


Instruction: The Work Group felt that the simplicity of an age-based approach would enhance what?

Output: uptake ofthe guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Work Group felt that the simplicity of an age-based approach would enhance what?. ### Response: uptake ofthe guideline.


Instruction: What did the group feel would enhance uptake of the guideline while allowing sufficiently accurate riskprediction?

Output: thesimplicity of an age-based approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the group feel would enhance uptake of the guideline while allowing sufficiently accurate riskprediction?. ### Response: thesimplicity of an age-based approach.


Instruction: What did SHARP indicate that simvastatin/ezetimibe combination therapy reduces the risk of major atherosclerotic events?

Output: The Study of Heart and Renal Protection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did SHARP indicate that simvastatin/ezetimibe combination therapy reduces the risk of major atherosclerotic events?. ### Response: The Study of Heart and Renal Protection.


Instruction: What does statins reduce the relative risk ofcardiovascular events to a similar extent among patients with CKD at baseline?

Output: 410 per 1000 patient-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does statins reduce the relative risk ofcardiovascular events to a similar extent among patients with CKD at baseline?. ### Response: 410 per 1000 patient-years.


Instruction: What are the post hoc analyses of statin versus placebo supported by?

Output: randomized trials of statin versus placebo that focus on thesubset of participants with CKD at baseline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the post hoc analyses of statin versus placebo supported by?. ### Response: randomized trials of statin versus placebo that focus on thesubset of participants with CKD at baseline.


Instruction: What is the relative risk ofcardiovascular events to a similar extent among patients with diabetes?

Output: 410

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the relative risk ofcardiovascular events to a similar extent among patients with diabetes?. ### Response: 410.


Instruction: What is the name of the yearly search of Embase OVID?

Output: OVID

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the yearly search of Embase OVID?. ### Response: OVID.


Instruction: What is one of the search portals for trialregistries?

Output: International ClinicalTrials Register

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the search portals for trialregistries?. ### Response: International ClinicalTrials Register.


Instruction: The updated search examined what databases?

Output: MEDLINE, Cochrane Central Registry ofControlled Trials, and Embase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The updated search examined what databases?. ### Response: MEDLINE, Cochrane Central Registry ofControlled Trials, and Embase.


Instruction: What did the Cochrane Kidney and Transplant Registry of studies search for?

Output: clinical questions that included only RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Cochrane Kidney and Transplant Registry of studies search for?. ### Response: clinical questions that included only RCTs.


Instruction: What was searched for only RCTs?

Output: clinical questions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was searched for only RCTs?. ### Response: clinical questions.


Instruction: What databases were searched for clinicalquestions that included non-CKD populations?

Output: MED-LINE and Embase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What databases were searched for clinicalquestions that included non-CKD populations?. ### Response: MED-LINE and Embase.


Instruction: What are the search strategies provided in?

Output: Appendix A: Supplementary Table S1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the search strategies provided in?. ### Response: Appendix A: Supplementary Table S1.


Instruction: How many ERT members screened titles and abstracts?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ERT members screened titles and abstracts?. ### Response: 2.


Instruction: Who independently assessed retrieved abstracts and if necessary, the full text to determine which studies satisfied the inclusion criteria?

Output: 2 ERT members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who independently assessed retrieved abstracts and if necessary, the full text to determine which studies satisfied the inclusion criteria?. ### Response: 2 ERT members.


Instruction: What resolved disagreement about inclusion?

Output: discussion with a third member of the ERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What resolved disagreement about inclusion?. ### Response: discussion with a third member of the ERT.


Instruction: How many total citations were screened?

Output: 6863

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many total citations were screened?. ### Response: 6863.


Instruction: How many citations were screened?

Output: 6863

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many citations were screened?. ### Response: 6863.


Instruction: How many observational studies were included in the evidence review?

Output: 14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many observational studies were included in the evidence review?. ### Response: 14.


Instruction: Who performed data extraction?

Output: 2 members of the ERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who performed data extraction?. ### Response: 2 members of the ERT.


Instruction: Who clarified data by contacting the author of the study report?

Output: 2 ERT members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who clarified data by contacting the author of the study report?. ### Response: 2 ERT members.


Instruction: Who designed data extraction forms to capture data on study design, participant characteristics,intervention and comparator characteristics, and critical and important outcomes?

Output: The ERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who designed data extraction forms to capture data on study design, participant characteristics,intervention and comparator characteristics, and critical and important outcomes?. ### Response: The ERT.


Instruction: What was used to resolve differences in extraction between mem-bers of the ERT?

Output: discussion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was used to resolve differences in extraction between mem-bers of the ERT?. ### Response: discussion.


Instruction: A third reviewer was included if what could not be achieved?

Output: consensus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A third reviewer was included if what could not be achieved?. ### Response: consensus.


Instruction: The majority of reviews undertakenwere intervention reviews that included what?

Output: RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The majority of reviews undertakenwere intervention reviews that included what?. ### Response: RCTs.


Instruction: What tool was used to assess individual studylimitations based on the following items383?

Output: Cochrane Risk of Bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tool was used to assess individual studylimitations based on the following items383?. ### Response: Cochrane Risk of Bias.


Instruction: Was there adequate sequence generation (selection bias)?

Output: C15Was there adequate sequence generation (selection bias)?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Was there adequate sequence generation (selection bias)?. ### Response: C15Was there adequate sequence generation (selection bias)?.


Instruction: Is knowledge of the allocated interventions adequately pre-vented during the study (detection bias?)

Output: Was knowledge of the allocated interventions adequately pre-vented

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is knowledge of the allocated interventions adequately pre-vented during the study (detection bias?). ### Response: Was knowledge of the allocated interventions adequately pre-vented.


Instruction: What is performance bias?

Output: Participants and personnel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performance bias?. ### Response: Participants and personnel.


Instruction: What is detectionbias?

Output: knowledge of the allocated interventions adequately pre-vented during the study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is detectionbias?. ### Response: knowledge of the allocated interventions adequately pre-vented during the study.


Instruction: Are reports of the study free of suggestion of selective outcome reporting?

Output: Unclear data were clari ﬁed by contactingthe author of the study report, and any relevant data obtained in thismanner were included

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Are reports of the study free of suggestion of selective outcome reporting?. ### Response: Unclear data were clari ﬁed by contactingthe author of the study report, and any relevant data obtained in thismanner were included.


Instruction: What did the ERT conduct for which there were no RCTs in the CKDpopulation?

Output: reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ERT conduct for which there were no RCTs in the CKDpopulation?. ### Response: reviews.


Instruction: Who was discharged alive after PCI after exclusion of patients with a contraindication to or history of intolerance of statins?

Output: tients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was discharged alive after PCI after exclusion of patients with a contraindication to or history of intolerance of statins?. ### Response: tients.


Instruction: What remains an opportunity for substantial improvement in the use of these medications in patientsundergoing PCI?

Output: Explicit physicianreferral of patients to cardiac rehabilitation has been shownto substantially increase the likelihood of patient enroll-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains an opportunity for substantial improvement in the use of these medications in patientsundergoing PCI?. ### Response: Explicit physicianreferral of patients to cardiac rehabilitation has been shownto substantially increase the likelihood of patient enroll-ment.


Instruction: Post-PCI order sets and having a detailed discussion of theirbenefits can be very effective at ensuring what?

Output: patient adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Post-PCI order sets and having a detailed discussion of theirbenefits can be very effective at ensuring what?. ### Response: patient adherence.


Instruction: What measure harmonizes closely with the correspondingility-level postprocedural optimal medical therapy?

Output: Cardiac Rehabilitation Patient Referral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What measure harmonizes closely with the correspondingility-level postprocedural optimal medical therapy?. ### Response: Cardiac Rehabilitation Patient Referral.


Instruction: What is a multidisciplinary exercise-basedoutpatient service called?

Output: Cardiac Rehabilitation Patient ReferralCardiac rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a multidisciplinary exercise-basedoutpatient service called?. ### Response: Cardiac Rehabilitation Patient ReferralCardiac rehabilitation.


Instruction: What has been proven to provide improved functional status, quality oflife, medical resource use, and ultimately, mortality rate reduction?

Output: Cardiac Rehabilitation Patient ReferralCardiac rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been proven to provide improved functional status, quality oflife, medical resource use, and ultimately, mortality rate reduction?. ### Response: Cardiac Rehabilitation Patient ReferralCardiac rehabilitation.


Instruction: Patients with coronary artery disease treated with PCI are at high risk of what?

Output: recurrent events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with coronary artery disease treated with PCI are at high risk of what?. ### Response: recurrent events.


Instruction: What is a vastly underutilized service?

Output: cardiac rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a vastly underutilized service?. ### Response: cardiac rehabilitation.


Instruction: How many eligible patients enroll in aprogram?

Output: less than half

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many eligible patients enroll in aprogram?. ### Response: less than half.


Instruction: What are numerous barriers to referral, entry, and completion of cardiac rehabilitation by patients?

Output: physician referral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are numerous barriers to referral, entry, and completion of cardiac rehabilitation by patients?. ### Response: physician referral.


Instruction: What are some barriers to referral,entry, and completion of cardiac rehabilitation by patients?

Output: lack of a geographically convenient program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some barriers to referral,entry, and completion of cardiac rehabilitation by patients?. ### Response: lack of a geographically convenient program.


Instruction: What is a modi fiable barrier?

Output: physician referral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a modi fiable barrier?. ### Response: physician referral.


Instruction: Explicit physician referral has been shownto substantially increase the likelihood of what?

Output: patient enroll-ment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Explicit physician referral has been shownto substantially increase the likelihood of what?. ### Response: patient enroll-ment.


Instruction: What is shown to substantially increase the likelihood of patient enroll-ment?

Output: Explicit physicianreferral of patients to cardiac rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shown to substantially increase the likelihood of patient enroll-ment?. ### Response: Explicit physicianreferral of patients to cardiac rehabilitation.


Instruction: What should be part of the comprehensive care of a patient undergoing PCI?

Output: cardiac rehabilitation referral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be part of the comprehensive care of a patient undergoing PCI?. ### Response: cardiac rehabilitation referral.


Instruction: What should be part of comprehensive care of a patient undergoing PCI?

Output: cardiac rehabilitation referral

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be part of comprehensive care of a patient undergoing PCI?. ### Response: cardiac rehabilitation referral.


Instruction: Referral during the index hospitalization for PCIis therefore optimal what?

Output: The performance measure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Referral during the index hospitalization for PCIis therefore optimal what?. ### Response: The performance measure.


Instruction: What takes into account appropriate exclusions?

Output: The performance measure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What takes into account appropriate exclusions?. ### Response: The performance measure.


Instruction: What is an example of a medical non-suitability?

Output: history of comorbidities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a medical non-suitability?. ### Response: history of comorbidities.


Instruction: What is a possible future use of this measure?

Output: broadening this measure to assess levels of participation onthe basis of attendance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible future use of this measure?. ### Response: broadening this measure to assess levels of participation onthe basis of attendance.


Instruction: What should every cath-eterization laboratory participate in for benchmarking purposes?

Output: a national orregional PCI registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should every cath-eterization laboratory participate in for benchmarking purposes?. ### Response: a national orregional PCI registry.


Instruction: What is the benefit of participating in a registry?

Output: ability toJACC Vol. 63, No. 7, 2014 Nallamothu et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of participating in a registry?. ### Response: ability toJACC Vol. 63, No. 7, 2014 Nallamothu et al.


Instruction: What are the benefits of participating in a registry?

Output: ability toJACC Vol. 63, No. 7, 2014 Nallamothu et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the benefits of participating in a registry?. ### Response: ability toJACC Vol. 63, No. 7, 2014 Nallamothu et al.


Instruction: Nallamothu et al.

Output: PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Nallamothu et al.. ### Response: PCI.


Instruction: What is the acronym for data safety monitoring board?

Output: DSMB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for data safety monitoring board?. ### Response: DSMB.


Instruction: What is HRS?

Output: Heart Rhythm Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HRS?. ### Response: Heart Rhythm Society.


Instruction: Where is the University of California, Los Angeles?

Output: UCLA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the University of California, Los Angeles?. ### Response: UCLA.


Instruction: What are the 2013 ACCF/AHA Heart Failure Guidelines: Executive Summary1539Downloaded From: http://content.onlinejacc.org/ on 04/17/2014

Output: 1495 –539

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2013 ACCF/AHA Heart Failure Guidelines: Executive Summary1539Downloaded From: http://content.onlinejacc.org/ on 04/17/2014. ### Response: 1495 –539.


Instruction: What is the name of the Norwegian randomized trial?

Output: Transmyocardial revas-cularization with CO2 laser in patients with refractory angina pectoris.Clinical results from the Norwegian randomized trial. J Am CollCardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Norwegian randomized trial?. ### Response: Transmyocardial revas-cularization with CO2 laser in patients with refractory angina pectoris.Clinical results from the Norwegian randomized trial. J Am CollCardiol.


Instruction: What is a common cause of angina pectoris?

Output: ref ractory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of angina pectoris?. ### Response: ref ractory.


Instruction: How does a carbon dioxide laser treat end-stage coronaryartery disease?

Output: Transmyocardial revasculariza-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does a carbon dioxide laser treat end-stage coronaryartery disease?. ### Response: Transmyocardial revasculariza-tion.


Instruction: What does a carbon dioxide laser do in patients with end-stage coronaryartery disease?

Output: Transmyocardial revasculariza-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a carbon dioxide laser do in patients with end-stage coronaryartery disease?. ### Response: Transmyocardial revasculariza-tion.


Instruction: What relieves angina and improves func-tional status?

Output: Holmium:YAG lasertransmyocardial revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What relieves angina and improves func-tional status?. ### Response: Holmium:YAG lasertransmyocardial revascularization.


Instruction: What is the effect of transmyo-cardial laser revascularization and thoracic sympathectomy on refractory angina?

Output: Efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of transmyo-cardial laser revascularization and thoracic sympathectomy on refractory angina?. ### Response: Efficacy.


Instruction: When was the Ann Thorac Surg.78:122–8.927?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Thorac Surg.78:122–8.927?. ### Response: 2004.


Instruction: What was the outcome of the prospective randomised trial?

Output: 5-year follow-up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the prospective randomised trial?. ### Response: 5-year follow-up.


Instruction: What is a prospective randomised trial of angina pectoris?

Output: Transmyocardial laserrevascularisation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prospective randomised trial of angina pectoris?. ### Response: Transmyocardial laserrevascularisation.


Instruction: What is angina treatment-lasers and nor malTherapies in comparison?

Output: normal population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is angina treatment-lasers and nor malTherapies in comparison?. ### Response: normal population.


Instruction: When did the Lancet issue 354:885-90.928?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet issue 354:885-90.928?. ### Response: 1999.


Instruction: What is the name of the randomised trial of transmyocardial laserrevascularisation in patients with refractory angina?

Output: Norwegian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial of transmyocardial laserrevascularisation in patients with refractory angina?. ### Response: Norwegian.


Instruction: How long does it take for a patient to have a transmycardial revascu-larization?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a patient to have a transmycardial revascu-larization?. ### Response: 5-year.


Instruction: What are the names of the authors of the trial?

Output: Schofield PM, Sharples LD, Caine N

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the trial?. ### Response: Schofield PM, Sharples LD, Caine N.


Instruction: How long did the follow-up of a prospective, randomized multicentertrial last?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the follow-up of a prospective, randomized multicentertrial last?. ### Response: 5-year.


Instruction: What is the name of the study that investigated the effects of transmyocardial revascu-larization?

Output: Norwegian randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effects of transmyocardial revascu-larization?. ### Response: Norwegian randomized trial.


Instruction: How many patients might be eligible for direct myocardial revascularization and angiogenesis?

Output: how many patients might be eligible? Am JCardiol. 1999;84:598–600, A8.934

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients might be eligible for direct myocardial revascularization and angiogenesis?. ### Response: how many patients might be eligible? Am JCardiol. 1999;84:598–600, A8.934.


Instruction: What is the name of the group that studies the appropriateness of referral of coronary angiography patients in Sweden?

Output: SECOR/SBU Projec tGroup

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies the appropriateness of referral of coronary angiography patients in Sweden?. ### Response: SECOR/SBU Projec tGroup.


Instruction: What is the name of the SECOR/SBU Projec tGroup?

Output: SECOR/SBU Projec tGroup

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the SECOR/SBU Projec tGroup?. ### Response: SECOR/SBU Projec tGroup.


Instruction: How long after coronary revascularisation is quality of life of patients with chronic stable angina compared with a normal population?

Output: four years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after coronary revascularisation is quality of life of patients with chronic stable angina compared with a normal population?. ### Response: four years.


Instruction: What does external counterpulsation do toplasma nitric acid?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does external counterpulsation do toplasma nitric acid?. ### Response: Effect.


Instruction: What is the effect of external counterpulsation on endothelin-1 and nitric oxide levels?

Output: improves endothelial function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of external counterpulsation on endothelin-1 and nitric oxide levels?. ### Response: improves endothelial function.