Instruction: What year did NICE publish a report on referral and approach to care for Chronic Heart Failure?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did NICE publish a report on referral and approach to care for Chronic Heart Failure?. ### Response: 2018.


Instruction: What is the name of the book published by Peters-Klimm?

Output: HICMann

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book published by Peters-Klimm?. ### Response: HICMann.


Instruction: What is the difference between case management and primary care?

Output: VERY LOW

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between case management and primary care?. ### Response: VERY LOW.


Instruction: How long does it take to achieve HFREF Outcomes?

Output: >6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to achieve HFREF Outcomes?. ### Response: >6 months.


Instruction: What is GRADE?

Output: Quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GRADE?. ### Response: Quality of the evidence.


Instruction: What is the risk difference with MDTcm (95% CI)?

Output: Hospitalisations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk difference with MDTcm (95% CI)?. ### Response: Hospitalisations.


Instruction: Hospitalisations 178 (1 study) 12 months  VERY LOWa, b due to what?

Output: risk of bias, imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hospitalisations 178 (1 study) 12 months  VERY LOWa, b due to what?. ### Response: risk of bias, imprecision.


Instruction: Imprecision rate ratio 1.23 (0.78 to 1.94) 374 per 1000 86 more admissions per 1 study?

Output: risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Imprecision rate ratio 1.23 (0.78 to 1.94) 374 per 1000 86 more admissions per 1 study?. ### Response: risk of bias.


Instruction: How many admissions per 1 000 were there?

Output: 86

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many admissions per 1 000 were there?. ### Response: 86.


Instruction: How many deaths per 1 study?

Output: 190

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many deaths per 1 study?. ### Response: 190.


Instruction: Why was the death rate so low?

Output: risk of bias, imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the death rate so low?. ### Response: risk of bias, imprecision.


Instruction: What was the risk of bias?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of bias?. ### Response: imprecision.


Instruction: What is the final score of the Kansas City Cardiomyopathy Questionnaire?

Output: higher=better

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the final score of the Kansas City Cardiomyopathy Questionnaire?. ### Response: higher=better.


Instruction: How many studies were conducted?

Output: 131

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were conducted?. ### Response: 131.


Instruction: What was the scale from 0 to 100?

Output: VERY LOW

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the scale from 0 to 100?. ### Response: VERY LOW.


Instruction: What was the mean KCCQ in the intervention groups?

Output: 1.70 higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean KCCQ in the intervention groups?. ### Response: 1.70 higher.


Instruction: How long did the study last?

Output: 12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: 12 months.


Instruction: Why was the final score in the control groups LOW?

Output: risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the final score in the control groups LOW?. ### Response: risk of bias.


Instruction: What is the final score of the SF-36 physical health composite?

Output: higher=better

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the final score of the SF-36 physical health composite?. ### Response: higher=better.


Instruction: What is higher=better?

Output: Quality of life  Kansas City Cardiomyopathy Questionnaire, final score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is higher=better?. ### Response: Quality of life  Kansas City Cardiomyopathy Questionnaire, final score.


Instruction: How many studies were enrolled in the study?

Output: 180

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were enrolled in the study?. ### Response: 180.


Instruction: Why was there a risk of bias?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there a risk of bias?. ### Response: imprecision.


Instruction: How much lower was the mean SF-physical in the control groups?

Output: 38.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much lower was the mean SF-physical in the control groups?. ### Response: 38.3.


Instruction: What was the difference between the intervention groups and the control group?

Output: 0.1 lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between the intervention groups and the control group?. ### Response: 0.1 lower.


Instruction: How is the quality of life measured in the mental health composite?

Output: final score. higher=better

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the quality of life measured in the mental health composite?. ### Response: final score. higher=better.


Instruction: What is the final score of the SF-36 mental health composite?

Output: higher=better

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the final score of the SF-36 mental health composite?. ### Response: higher=better.


Instruction: Why was the mean SF -mental in the control groups 46.6?

Output: risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the mean SF -mental in the control groups 46.6?. ### Response: risk of bias.


Instruction: How much lower was the mean SF-mental in the intervention groups?

Output: 0.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much lower was the mean SF-mental in the intervention groups?. ### Response: 0.1.


Instruction: What was the risk of bias in the study?

Output: LOWa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of bias in the study?. ### Response: LOWa.


Instruction: How long did it take for ACE -I/ARB and B -blocker to be prescribed?

Output: 180 (1 study)  12 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for ACE -I/ARB and B -blocker to be prescribed?. ### Response: 180 (1 study)  12 months.


Instruction: LOWa due to risk of bias RR 1.01 (0.84 to 1.2) 720 ACE+BB per 1000 7 more ACE +BB per 10 00 (from 115 fewer to 144 more)

Output: LOWa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LOWa due to risk of bias RR 1.01 (0.84 to 1.2) 720 ACE+BB per 1000 7 more ACE +BB per 10 00 (from 115 fewer to 144 more). ### Response: LOWa.


Instruction: What could be implemented safely and are urgently needed?

Output: food substitution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be implemented safely and are urgently needed?. ### Response: food substitution.


Instruction: What are the recommendations for Obstructive Sleep Apnea summarized in online Data Supplements 18 and 19?

Output: Referenced studies that support recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for Obstructive Sleep Apnea summarized in online Data Supplements 18 and 19?. ### Response: Referenced studies that support recommendations.


Instruction: What can be beneficial for improved sleep apnea, BP, sleepiness, and other outcomes?

Output: treatment with positive airway pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial for improved sleep apnea, BP, sleepiness, and other outcomes?. ### Response: treatment with positive airway pressure.


Instruction: In patients with an ischemic stroke or TIA, an evaluation for OSA may be considered for diagnosing what?

Output: sleep apnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with an ischemic stroke or TIA, an evaluation for OSA may be considered for diagnosing what?. ### Response: sleep apnea.


Instruction: What may be considered for diagnosing sleep apnea?

Output: an evaluation for OSA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for diagnosing sleep apnea?. ### Response: an evaluation for OSA.


Instruction: What is diagnosed by polysomnography to calcu-late the AHI?

Output: Sleep apnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is diagnosed by polysomnography to calcu-late the AHI?. ### Response: Sleep apnea.


Instruction: How long is total cessation of airflow for?

Output: 10 seconds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is total cessation of airflow for?. ### Response: 10 seconds.


Instruction: How much for 10 seconds with reduced oxygen saturation?

Output: hypopneas (reduction in airflow by at least 30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much for 10 seconds with reduced oxygen saturation?. ### Response: hypopneas (reduction in airflow by at least 30%.


Instruction: What is the threshold for diagnosis?

Output: AHI ≥ 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the threshold for diagnosis?. ### Response: AHI ≥ 5.


Instruction: How much is the prevalence of moderate to severe sleep apnea among US adults 50 to 70 years of age?

Output: 10%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much is the prevalence of moderate to severe sleep apnea among US adults 50 to 70 years of age?. ### Response: 10%..


Instruction: What is the prevalence of sleep apnea in men and women?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of sleep apnea in men and women?. ### Response: higher.


Instruction: What are some of the risk factors associated with sleep-related mortality?

Output: heart disease,320 hypertension,322 and AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the risk factors associated with sleep-related mortality?. ### Response: heart disease,320 hypertension,322 and AF.


Instruction: Sleep-related hypertension is a risk factor for what type of disease?

Output: heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sleep-related hypertension is a risk factor for what type of disease?. ### Response: heart.


Instruction: What affects 38% to 40% of patients with stroke?

Output: Sleep apnea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What affects 38% to 40% of patients with stroke?. ### Response: Sleep apnea.


Instruction: What percentage of stroke cases are OSA rather than central sleep apnea?

Output: >90%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of stroke cases are OSA rather than central sleep apnea?. ### Response: >90%.


Instruction: What is the risk for func-tional impairment, stroke recurrence, and death?

Output: increased risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk for func-tional impairment, stroke recurrence, and death?. ### Response: increased risk.


Instruction: What is CPAP safe after after stroke?

Output: reduces the AHI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CPAP safe after after stroke?. ### Response: reduces the AHI.


Instruction: What is the acronym for Sleep Apnea Cardiovascular Endpoints?

Output: SAVE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Sleep Apnea Cardiovascular Endpoints?. ### Response: SAVE.


Instruction: What was the risk for stroke among participants in the SAVE study?

Output: lower

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk for stroke among participants in the SAVE study?. ### Response: lower.


Instruction: Who had a better adherence to CPAP therapy?

Output: participants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who had a better adherence to CPAP therapy?. ### Response: participants.


Instruction: What is the HR of CPAP therapy?

Output: 0.56

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the HR of CPAP therapy?. ### Response: 0.56.


Instruction: What does the American College of Physicians recommend as the initial therapy for OSA patients?

Output: CPAP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the American College of Physicians recommend as the initial therapy for OSA patients?. ### Response: CPAP.


Instruction: What did treatment with CPAP reduce?

Output: AHI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did treatment with CPAP reduce?. ### Response: AHI.


Instruction: What was improved by treatment?

Output: sleepiness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was improved by treatment?. ### Response: sleepiness.


Instruction: Where can data from small trials be found?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can data from small trials be found?. ### Response: http://ahajournals.org.


Instruction: On what date will CPAP be downloaded from http://ahajournals.org?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date will CPAP be downloaded from http://ahajournals.org?. ### Response: April 28, 2023.


Instruction: What is essential to make an informed decision?

Output: elicit the breadth of theirknowledge, values, preferences, and concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is essential to make an informed decision?. ### Response: elicit the breadth of theirknowledge, values, preferences, and concerns.


Instruction: Who has a responsibility to ensure thatpatients understand and consider both the upside and down-side of options?

Output: The healthcare provider

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has a responsibility to ensure thatpatients understand and consider both the upside and down-side of options?. ### Response: The healthcare provider.


Instruction: What role do patient preferences play in the selection of a treatment strategy?

Output: crucial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What role do patient preferences play in the selection of a treatment strategy?. ### Response: crucial.


Instruction: What must be conducted in a location and atmosphere that permits adequate time for discussion and contemplation?

Output: these discussions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be conducted in a location and atmosphere that permits adequate time for discussion and contemplation?. ### Response: these discussions.


Instruction: What is the objective in crafting a diagnostic strategy?

Output: to ascer-tain, as accurately as possible

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the objective in crafting a diagnostic strategy?. ### Response: to ascer-tain, as accurately as possible.


Instruction: What is not consistent with these principles?

Output: Initiating a discussion about the relative merits of PCI orCABG while a patient is in the midst of a procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not consistent with these principles?. ### Response: Initiating a discussion about the relative merits of PCI orCABG while a patient is in the midst of a procedure.


Instruction: What should be emphasized incases of a false positive or falsenegative result?

Output: Treatment options

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be emphasized incases of a false positive or falsenegative result?. ### Response: Treatment options.


Instruction: What is the objective for procedures intended to assess?

Output: prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the objective for procedures intended to assess?. ### Response: prognosis.


Instruction: What should be emphasized in cases where there is no substantial advantage of one strategy over another?

Output: Treatment options

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be emphasized in cases where there is no substantial advantage of one strategy over another?. ### Response: Treatment options.


Instruction: For most patients, the goal of treatment should be to maximize what?

Output: survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For most patients, the goal of treatment should be to maximize what?. ### Response: survival.


Instruction: What is a functional capacity of Canadian Cardiovascular Society Class I angina?

Output: afunctional

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a functional capacity of Canadian Cardiovascular Society Class I angina?. ### Response: afunctional.


Instruction: What is the treatment goal for an otherwise healthy, active patient?

Output: complete elimination of chest pain and a return to vigorousphysical activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the treatment goal for an otherwise healthy, active patient?. ### Response: complete elimination of chest pain and a return to vigorousphysical activity.


Instruction: For an elderly patient with moresevere angina, what is the goal?

Output: a reduction in symptoms thatpermits limited activities of daily living

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For an elderly patient with moresevere angina, what is the goal?. ### Response: a reduction in symptoms thatpermits limited activities of daily living.


Instruction: What type of activity might a patient with more severe angina be satisfied with?

Output: limited activities of daily living

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of activity might a patient with more severe angina be satisfied with?. ### Response: limited activities of daily living.


Instruction: What kind of comorbidities could make the risk of surgery unacceptable?

Output: Patients with anat-omy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What kind of comorbidities could make the risk of surgery unacceptable?. ### Response: Patients with anat-omy.


Instruction: What is a more attractive option if there are comorbidities that make surgery unacceptable?

Output: PCI or medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a more attractive option if there are comorbidities that make surgery unacceptable?. ### Response: PCI or medical therapy.


Instruction: What should the healthcare provider be aware of and help to rectify?

Output: common misperceptions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the healthcare provider be aware of and help to rectify?. ### Response: common misperceptions.


Instruction: Many patients assume that opening a partially blocked artery will naturally prevent what?

Output: a heart attack

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Many patients assume that opening a partially blocked artery will naturally prevent what?. ### Response: a heart attack.


Instruction: What prevents a heart attack?

Output: opening a partially blockedartery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What prevents a heart attack?. ### Response: opening a partially blockedartery.


Instruction: What will a partially blocked artery do?

Output: prevent a heart attack and prolong life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What will a partially blocked artery do?. ### Response: prevent a heart attack and prolong life.


Instruction: What is a risk factor for adverse outcomes in patients undergoing many types ofsurgery?

Output: Intraoperative hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for adverse outcomes in patients undergoing many types ofsurgery?. ### Response: Intraoperative hypotension.


Instruction: What are unavoidable periods of hypotension associated with?

Output: surgical manipulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are unavoidable periods of hypotension associated with?. ### Response: surgical manipulation.


Instruction: What is recommended in patients with acute MI?

Output: Emergency CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with acute MI?. ### Response: Emergency CABG.


Instruction: What is often difficult to achieve in patients who are unstable hemodynamically?

Output: Minimization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often difficult to achieve in patients who are unstable hemodynamically?. ### Response: Minimization.


Instruction: When is emergency CABG recommended?

Output: un-dergoing surgical repair of a postinfarction mechan-ical complication of MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is emergency CABG recommended?. ### Response: un-dergoing surgical repair of a postinfarction mechan-ical complication of MI.


Instruction: What is suit-able for CABG?

Output: coronary anatomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is suit-able for CABG?. ### Response: coronary anatomy.


Instruction: What is recommended in patients un-dergoing surgical repair of a postinfarction mechan-ical complication of MI?

Output: Emergency CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients un-dergoing surgical repair of a postinfarction mechan-ical complication of MI?. ### Response: Emergency CABG.


Instruction: What is an example of an emergency CABG?

Output: ventricular septalrupture, mitral valve insufficiency because of papil-lary muscle infarction and/or rupture, or free wallrupture

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an emergency CABG?. ### Response: ventricular septalrupture, mitral valve insufficiency because of papil-lary muscle infarction and/or rupture, or free wallrupture.


Instruction: What is the Level of Evidence?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence?. ### Response: B.


Instruction: When was e664 Circulated from http://ahajournals.org

Output: December 6, 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was e664 Circulated from http://ahajournals.org. ### Response: December 6, 2011.


Instruction: What is the name of the ICH ADAPT Investigators?

Output: Antihypertensive Treatment of Acute Cerebral Hemorrhage Study Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ICH ADAPT Investigators?. ### Response: Antihypertensive Treatment of Acute Cerebral Hemorrhage Study Investigators.


Instruction: What is one of the results of the Intracerebral Hemorrhage Acute Decreasing Arterial Pressure Trial?

Output: Intensive blood pressure reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the results of the Intracerebral Hemorrhage Acute Decreasing Arterial Pressure Trial?. ### Response: Intensive blood pressure reduction.


Instruction: What does systolic blood pressure reduction do to hematoma expansion, perihematomal edema, and 3-month outcome among patients with cerebral hemorrhage?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does systolic blood pressure reduction do to hematoma expansion, perihematomal edema, and 3-month outcome among patients with cerebral hemorrhage?. ### Response: Effect.


Instruction: What is the name of the study investigators?

Output: ICH ADAPT Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study investigators?. ### Response: ICH ADAPT Investigators.


Instruction: What is the 3-month outcome among patients with intracerebral hemorrhage?

Output: Effect of systolic blood pressure reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 3-month outcome among patients with intracerebral hemorrhage?. ### Response: Effect of systolic blood pressure reduction.


Instruction: What was the name of the study?

Output: Antihypertensive Treatment of Acute Cerebral Hemorrhage Study Investigators. Effect of systolic blood pressure reduction on hematoma expansion, perihematomal edema, and 3-month outcome among patients with intracerebral hemorrhage: results from the Antihypertensive Treatment of Acute Cerebral Hemorrhage Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: Antihypertensive Treatment of Acute Cerebral Hemorrhage Study Investigators. Effect of systolic blood pressure reduction on hematoma expansion, perihematomal edema, and 3-month outcome among patients with intracerebral hemorrhage: results from the Antihypertensive Treatment of Acute Cerebral Hemorrhage Study.


Instruction: How long did it take for patients to recover?

Output: 3-month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for patients to recover?. ### Response: 3-month.


Instruction: When was the Arch Neurol.67:570-576?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Arch Neurol.67:570-576?. ### Response: 2010.


Instruction: What is INTERACT?

Output: Intensive blood pressure reduction in acute cerebral haemorrhage trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is INTERACT?. ### Response: Intensive blood pressure reduction in acute cerebral haemorrhage trial.


Instruction: What is the name of the randomised pilot trial?

Output: INTERACT Investigators. Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised pilot trial?. ### Response: INTERACT Investigators. Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT.


Instruction: When was the Lancet Neurol 7:391–399.

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet Neurol 7:391–399.. ### Response: 2008.


Instruction: What was the outcome of the INTERACT1 pilot study?

Output: Earlier blood pressure-lowering and greater attenuation of hematoma growth in acute intracerebral hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the INTERACT1 pilot study?. ### Response: Earlier blood pressure-lowering and greater attenuation of hematoma growth in acute intracerebral hemorrhage.


Instruction: What is the name of the pilot phase of attenuation of hematoma growth in acute intracerebral hemorrhage?

Output: INTERACT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pilot phase of attenuation of hematoma growth in acute intracerebral hemorrhage?. ### Response: INTERACT.


Instruction: When was the INTERACT pilot phase?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the INTERACT pilot phase?. ### Response: 2012.


Instruction: What was the doi: 10.1161/STROKEAHA.112.651422.

Output: Stroke. 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the doi: 10.1161/STROKEAHA.112.651422.. ### Response: Stroke. 2012.


Instruction: What is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage?

Output: Lower treatment blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage?. ### Response: Lower treatment blood pressure.


Instruction: What is the doi: 10.1161/HYPERTENSIONAHA.110.154328?

Output: 2010;56:852–858

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1161/HYPERTENSIONAHA.110.154328?. ### Response: 2010;56:852–858.


Instruction: What type of hemorrhage is involved in intracerebral bleeding?

Output: acute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hemorrhage is involved in intracerebral bleeding?. ### Response: acute.


Instruction: What is the most recent issue of Hypertension?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most recent issue of Hypertension?. ### Response: 2010.


Instruction: Who is the author of the paper Hypertension in 2010?

Output: Arima H, Anderson CS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the paper Hypertension in 2010?. ### Response: Arima H, Anderson CS.


Instruction: What does rapid blood-pressure lowering do in patients with acute intracerebral hemorrhage?

Output: hematoma expansion, perihematomal edema, and 3-month outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does rapid blood-pressure lowering do in patients with acute intracerebral hemorrhage?. ### Response: hematoma expansion, perihematomal edema, and 3-month outcome.


Instruction: What is a critical review of ischemic brain injury?

Output: Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a critical review of ischemic brain injury?. ### Response: Stroke.


Instruction: When did Stroke.43:2258-2263 occur?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Stroke.43:2258-2263 occur?. ### Response: 2012.


Instruction: What is a critical review?

Output: Ischemic brain injury after intracerebral hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a critical review?. ### Response: Ischemic brain injury after intracerebral hemorrhage.


Instruction: What is associated with a reduced mortality rate after intrace-rebral hemorrhage?

Output: Admission to a neurologic/neurosurgical intensive care unit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with a reduced mortality rate after intrace-rebral hemorrhage?. ### Response: Admission to a neurologic/neurosurgical intensive care unit.


Instruction: What is the name of the study that compares aspirin and clopidogrel after recent ischaemic stroke?

Output: MATCH): randomised, double-blind, placebo-controlled trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares aspirin and clopidogrel after recent ischaemic stroke?. ### Response: MATCH): randomised, double-blind, placebo-controlled trial.


Instruction: When was the MATCH trial conducted?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the MATCH trial conducted?. ### Response: 2004.


Instruction: What was the outcome of the trial?

Output: Effect of intravenous APSAC on mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the trial?. ### Response: Effect of intravenous APSAC on mortality.


Instruction: How many patients were treated with MATCH?

Output: high-risk patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with MATCH?. ### Response: high-risk patients.


Instruction: Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke.

Output: Sacco RL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke.. ### Response: Sacco RL.


Instruction: N Engl J Med. 2008;359:1238–51.299.

Output: recurrent stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: N Engl J Med. 2008;359:1238–51.299.. ### Response: recurrent stroke.


Instruction: Ticagrelor versus what in patients with acute coronary syndromes?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ticagrelor versus what in patients with acute coronary syndromes?. ### Response: clopidogrel.


Instruction: Circulation. 2012;125:2914–21.300.

Output: recurrent stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2012;125:2914–21.300.. ### Response: recurrent stroke.


Instruction: Verheugt FWA. Beware of what?

Output: novel antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Verheugt FWA. Beware of what?. ### Response: novel antiplatelet therapy.


Instruction: What is ischemic attack?

Output: tran-sient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ischemic attack?. ### Response: tran-sient.


Instruction: What is the name of the randomized controlled trial that compares intracoronary versus intravenous abciximab in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention?

Output: CICERO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial that compares intracoronary versus intravenous abciximab in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention?. ### Response: CICERO.


Instruction: What is abciximab used for in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention?

Output: thrombus aspiration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is abciximab used for in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention?. ### Response: thrombus aspiration.


Instruction: What is the difference between intra-venous administration and intracoronary administration?

Output: Intracoronary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between intra-venous administration and intracoronary administration?. ### Response: Intracoronary.


Instruction: What is the CICERO trial?

Output: Comparison of Intracoronary Versus Intravenous Abciximab Administration During Emergency Re-perfusion of ST-Segment Elevation Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CICERO trial?. ### Response: Comparison of Intracoronary Versus Intravenous Abciximab Administration During Emergency Re-perfusion of ST-Segment Elevation Myocardial Infarction.


Instruction: What was the name of the trial that compared intracoronary versus intravenous abciximab administration during emergency re-perfusion of ST-Segment Elevation Myocardial Infarction?

Output: CICERO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the trial that compared intracoronary versus intravenous abciximab administration during emergency re-perfusion of ST-Segment Elevation Myocardial Infarction?. ### Response: CICERO.


Instruction: When was the Circulation.122:2709-17.303?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.122:2709-17.303?. ### Response: 2010.


Instruction: What is fondaparinux used for in patients with ST-segment elevation myocardial infarction?

Output: mortality and reinfarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is fondaparinux used for in patients with ST-segment elevation myocardial infarction?. ### Response: mortality and reinfarction.


Instruction: When was the OASIS-6 randomized trial conducted?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the OASIS-6 randomized trial conducted?. ### Response: 2006.


Instruction: What is the name of the study that investigated the use of enoxaparin or unfractionated heparin in primary percutaneous coronary intervention for ST-elevation myocardial infarction?

Output: ATOLL trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the use of enoxaparin or unfractionated heparin in primary percutaneous coronary intervention for ST-elevation myocardial infarction?. ### Response: ATOLL trial.


Instruction: When did the AIMS Trial Study Group report on the effect of intravenous APSAC on mortality?

Output: 1988

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the AIMS Trial Study Group report on the effect of intravenous APSAC on mortality?. ### Response: 1988.


Instruction: What was the effect of intravenous APSAC on mortality after acute myocardial infarction?

Output: preliminary report of a placebo-con-trolled clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of intravenous APSAC on mortality after acute myocardial infarction?. ### Response: preliminary report of a placebo-con-trolled clinical trial.


Instruction: What is the acronym for Estudio Multicéntrico Estreptoquinasa Repblicas de América del Sur?

Output: EMERAS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Estudio Multicéntrico Estreptoquinasa Repblicas de América del Sur?. ### Response: EMERAS.


Instruction: What is the second international study of infarct survival called?

Output: ISIS-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the second international study of infarct survival called?. ### Response: ISIS-2.


Instruction: How many cases of suspected acute myocardial infarction were randomized to ISIS-2?

Output: 17,187

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of suspected acute myocardial infarction were randomized to ISIS-2?. ### Response: 17,187.


Instruction: What is recommended for patients with significant ( >50% diameter stenosis)left main coronary artery stenosis?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with significant ( >50% diameter stenosis)left main coronary artery stenosis?. ### Response: CABG.


Instruction: What is a reasonable alterna-tive to CABG in selected stable patients?

Output: PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable alterna-tive to CABG in selected stable patients?. ### Response: PCI.


Instruction: What percentage of diameter stenosis is found in CABG in stable patients with unprotected leftmain CAD?

Output: >50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of diameter stenosis is found in CABG in stable patients with unprotected leftmain CAD?. ### Response: >50%.


Instruction: What is a low risk of PCI procedural complications and a high likelihood of good long-term outcome associated with?

Output: anatomic conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a low risk of PCI procedural complications and a high likelihood of good long-term outcome associated with?. ### Response: anatomic conditions.


Instruction: What predicts asignificant increased risk of adverse surgical out-comes?

Output: clinical characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts asignificant increased risk of adverse surgical out-comes?. ### Response: clinical characteristics.


Instruction: What is the STS-predicted risk of operative mortality>5%?

Output: increased risk of adverse surgical out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the STS-predicted risk of operative mortality>5%?. ### Response: increased risk of adverse surgical out-comes.


Instruction: How is PCI to improve survival in patients with UA/NSTEMI reasonable?

Output: when an unprotected left maincoronary artery is the culprit lesion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is PCI to improve survival in patients with UA/NSTEMI reasonable?. ### Response: when an unprotected left maincoronary artery is the culprit lesion.


Instruction: What is the culprit lesion and the patient is not a candidate for CABG?

Output: unprotected left maincoronary artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the culprit lesion and the patient is not a candidate for CABG?. ### Response: unprotected left maincoronary artery.


Instruction: PCI to improve survival is reasonable in patientswith acute STEMI when an unprotected left maincoronary artery is what?

Output: the culprit lesion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PCI to improve survival is reasonable in patientswith acute STEMI when an unprotected left maincoronary artery is what?. ### Response: the culprit lesion.


Instruction: Distal coronaryflow is less than what grade?

Output: TIMI (Thrombolysis In MyocardialInfarction) grade 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Distal coronaryflow is less than what grade?. ### Response: TIMI (Thrombolysis In MyocardialInfarction) grade 3.


Instruction: What is TIMI?

Output: Thrombolysis In MyocardialInfarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TIMI?. ### Response: Thrombolysis In MyocardialInfarction.


Instruction: What can be performed morerapiously and safely than CABG?

Output: PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be performed morerapiously and safely than CABG?. ### Response: PCI.


Instruction: How can PCI be performed?

Output: morerapidly and safely

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can PCI be performed?. ### Response: morerapidly and safely.


Instruction: What percentage of diameter stenosis is found in unprotectedleft main CAD?

Output: >50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of diameter stenosis is found in unprotectedleft main CAD?. ### Response: >50%.


Instruction: What is the risk of PCI proce-dural complications?

Output: low to intermediate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of PCI proce-dural complications?. ### Response: low to intermediate.


Instruction: A low-intermediate SYNTAX score of 33 indicates what type of outcome?

Output: good long-term outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A low-intermediate SYNTAX score of 33 indicates what type of outcome?. ### Response: good long-term outcome.


Instruction: What is the STS-predicted risk ofoperative mortality >2%?

Output: clinical characteristics thatpredict an increased risk of adverse surgical out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the STS-predicted risk ofoperative mortality >2%?. ### Response: clinical characteristics thatpredict an increased risk of adverse surgical out-comes.


Instruction: What is HARM1?

Output: Class III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HARM1?. ### Response: Class III.


Instruction: How should PCI be performed instable patients?

Output: rapidly and safely

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should PCI be performed instable patients?. ### Response: rapidly and safely.


Instruction: What should be performed instable patients with significant ( >50% diameterstenosis) unprotected left main CAD who have un-favorable anatomy for PCI and who are good can-didates for CABG?

Output: CABG to improve survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed instable patients with significant ( >50% diameterstenosis) unprotected left main CAD who have un-favorable anatomy for PCI and who are good can-didates for CABG?. ### Response: CABG to improve survival.


Instruction: How many major coronary arteries are there in patients with significant (>70% diameter) stenoses?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many major coronary arteries are there in patients with significant (>70% diameter) stenoses?. ### Response: 3.


Instruction: What type of CABG or PCI is beneficial insurvivors of sudden cardiac death with or without involve-ment of the proximal LAD plus 1 other majorcoronary artery?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of CABG or PCI is beneficial insurvivors of sudden cardiac death with or without involve-ment of the proximal LAD plus 1 other majorcoronary artery?. ### Response: CABG.


Instruction: What is beneficial insurvivors of sudden cardiac death with presumedischemia-mediated ventricular tachycardia?

Output: CABG or PCI to improve survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is beneficial insurvivors of sudden cardiac death with presumedischemia-mediated ventricular tachycardia?. ### Response: CABG or PCI to improve survival.


Instruction: What is the CABG Level of Evidence: B57-59?

Output: PCI Level of Evidence: C57

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CABG Level of Evidence: B57-59?. ### Response: PCI Level of Evidence: C57.


Instruction: What is a heteroge-neous population of patients with ACHD?

Output: general, pediatric, and ACHD cardiol-ogists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a heteroge-neous population of patients with ACHD?. ### Response: general, pediatric, and ACHD cardiol-ogists.


Instruction: What is the prevalence of ACHD in-creasing but the population with a given con-genital abnormality or specific repair may be?

Output: relatively  small

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of ACHD in-creasing but the population with a given con-genital abnormality or specific repair may be?. ### Response: relatively  small.


Instruction: What may be relatively small?

Output: the population of patients with a given con-genital abnormality or specific repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be relatively small?. ### Response: the population of patients with a given con-genital abnormality or specific repair.


Instruction: Patients with CHD are not cured of their disease after successful treatment in childhood?

Output: S1.4-3,S1.4-6–S1.4-8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with CHD are not cured of their disease after successful treatment in childhood?. ### Response: S1.4-3,S1.4-6–S1.4-8.


Instruction: Almost all patients with ACHD will have sequelae of what?

Output: either their native CHD or its surgical repair or palliation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Almost all patients with ACHD will have sequelae of what?. ### Response: either their native CHD or its surgical repair or palliation.


Instruction: What can take decades to man-ifest?

Output: sequelae

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can take decades to man-ifest?. ### Response: sequelae.


Instruction: The heterogeneity of the population and long, symptom-free intervals constrain the ability to generate data applicable across the population of ACHD or to adults with what?

Output: specific lesions or repairs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The heterogeneity of the population and long, symptom-free intervals constrain the ability to generate data applicable across the population of ACHD or to adults with what?. ### Response: specific lesions or repairs.


Instruction: What is a growing body of high-quality data in ACHD populations to guide the care of this relatively new population?

Output: develop recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a growing body of high-quality data in ACHD populations to guide the care of this relatively new population?. ### Response: develop recommendations.


Instruction: When feasible, these data were used to develop what?

Output: recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When feasible, these data were used to develop what?. ### Response: recommendations.


Instruction: When important clinical issues lacked data, first principles, extrapolation from data in other populations and expert consensus were used to guide care?

Output: first prin-ciples

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When important clinical issues lacked data, first principles, extrapolation from data in other populations and expert consensus were used to guide care?. ### Response: first prin-ciples.


Instruction: Patients with ACHD may have concomitant disease to which other existing guidelines apply, such as what?

Output: coronary ar -tery disease, HF, and arrhythmias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with ACHD may have concomitant disease to which other existing guidelines apply, such as what?. ### Response: coronary ar -tery disease, HF, and arrhythmias.


Instruction: What are three types of arrhythmias?

Output: S1.4-3–S1.4-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are three types of arrhythmias?. ### Response: S1.4-3–S1.4-5.


Instruction: What may apply to some patients with ACHD?

Output: The data from ac-quired heart disease populations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may apply to some patients with ACHD?. ### Response: The data from ac-quired heart disease populations.


Instruction: Who cares for ACHD patients in cen-ters?

Output: general, pediatric, and ACHD cardiol-ogists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who cares for ACHD patients in cen-ters?. ### Response: general, pediatric, and ACHD cardiol-ogists.


Instruction: What do cen-ters have better outcomes than?

Output: those cared for in cen-ters without ACHD expertise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do cen-ters have better outcomes than?. ### Response: those cared for in cen-ters without ACHD expertise.


Instruction: What need for spe-cialized care is noted throughout the guideline?

Output: CHD expertise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What need for spe-cialized care is noted throughout the guideline?. ### Response: CHD expertise.


Instruction: Who reviewed previously published guidelines and related scientific statements?

Output: the writing committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reviewed previously published guidelines and related scientific statements?. ### Response: the writing committee.


Instruction: What table contains a list of publications and scientific statements deemed per-tinent to the 2018 ACHD guideline?

Output: Table 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What table contains a list of publications and scientific statements deemed per-tinent to the 2018 ACHD guideline?. ### Response: Table 2.


Instruction: What is intended for use as a Download from http://ahajournals.org by on April 28, 2023?

Output: Table 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is intended for use as a Download from http://ahajournals.org by on April 28, 2023?. ### Response: Table 2.


Instruction: What is prasugrel used for in an emergency department?

Output: patients withUA/NSTEMI who have not undergone PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is prasugrel used for in an emergency department?. ### Response: patients withUA/NSTEMI who have not undergone PCI.


Instruction: What does the FDA pack-age label suggest?

Output: it is reasonable to consider selectiveuse of prasugrel before catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the FDA pack-age label suggest?. ### Response: it is reasonable to consider selectiveuse of prasugrel before catheterization.


Instruction: What does the writing group want to warn clinicians about?

Output: potential increased bleeding risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing group want to warn clinicians about?. ### Response: potential increased bleeding risks.


Instruction: What is a potential increase in bleeding?

Output: risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential increase in bleeding?. ### Response: risks.


Instruction: What does the group want to warn clinicians about?

Output: potential increased bleeding risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the group want to warn clinicians about?. ### Response: potential increased bleeding risks.


Instruction: Prasugrelor and ticagrelor are compared with which other drug?

Output: clopi-dogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prasugrelor and ticagrelor are compared with which other drug?. ### Response: clopi-dogrel.


Instruction: Why was prasugrel favored over other drugs?

Output: difference in nonfatal MIs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was prasugrel favored over other drugs?. ### Response: difference in nonfatal MIs.


Instruction: What was the main reason for the preference of the P2Y12receptor inhibitors over the other?

Output: efficacy in theprevention of thrombosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the main reason for the preference of the P2Y12receptor inhibitors over the other?. ### Response: efficacy in theprevention of thrombosis.


Instruction: Why was bleeding increased in the prasumgrel group?

Output: deaths and nonfatal strokes being similar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was bleeding increased in the prasumgrel group?. ### Response: deaths and nonfatal strokes being similar.


Instruction: The composite efficacy endpoint inTRITON–TIMI 38 favored which drug?

Output: prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The composite efficacy endpoint inTRITON–TIMI 38 favored which drug?. ### Response: prasugrel.


Instruction: What was the endpoint in PLATO favoring ticagrelor over clopidogrel driven by?

Output: differences in both vasculardeath and nonfatal MIs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the endpoint in PLATO favoring ticagrelor over clopidogrel driven by?. ### Response: differences in both vasculardeath and nonfatal MIs.


Instruction: What was associated with a notable reduction in all-causemortality?

Output: Ticagre-lor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a notable reduction in all-causemortality?. ### Response: Ticagre-lor.


Instruction: What was associated with a higher rate of non-CABG-related majorbleeding and slightly more frequent discontinuation of the studydrug due to adverse events?

Output: ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a higher rate of non-CABG-related majorbleeding and slightly more frequent discontinuation of the studydrug due to adverse events?. ### Response: ticagrelor.


Instruction: What did prasugrel have a significant increase in?

Output: the rate of TIMI majorhemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did prasugrel have a significant increase in?. ### Response: the rate of TIMI majorhemorrhage.


Instruction: What is TIMI major and non-CABG bleeding?

Output: hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TIMI major and non-CABG bleeding?. ### Response: hemorrhage.


Instruction: What was a signifi-cant interaction between the treatment effect in PLATO and thegeographic region?

Output: lack of benefit in the United States forticagrelor versus clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a signifi-cant interaction between the treatment effect in PLATO and thegeographic region?. ### Response: lack of benefit in the United States forticagrelor versus clopidogrel.


Instruction: In the United States, forticagrelor versus what drug?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the United States, forticagrelor versus what drug?. ### Response: clopidogrel.


Instruction: How many newer P2Y12receptor inhibitors were studied in different patient popula-tions?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many newer P2Y12receptor inhibitors were studied in different patient popula-tions?. ### Response: 2.


Instruction: What is the loading dose of clopidogrel inTRITON–TIMI?

Output: 38

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the loading dose of clopidogrel inTRITON–TIMI?. ### Response: 38.


Instruction: What was the loading dose of clopidogrel inTRITON-TIMI 38 lower than is currently recommended?

Output: 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the loading dose of clopidogrel inTRITON-TIMI 38 lower than is currently recommended?. ### Response: 7.


Instruction: Some emerging studies sug-gest there may be some patients who are resistant to what?

Output: clopi-dogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some emerging studies sug-gest there may be some patients who are resistant to what?. ### Response: clopi-dogrel.


Instruction: What can be used to select patients who might do better with newerP2Y12receptor inhibitors?

Output: strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to select patients who might do better with newerP2Y12receptor inhibitors?. ### Response: strategies.


Instruction: What are considerations of efficacy in the prevention ofthrombosis?

Output: risk of an adverse effect relatedto bleeding and experience with a given medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are considerations of efficacy in the prevention ofthrombosis?. ### Response: risk of an adverse effect relatedto bleeding and experience with a given medication.


Instruction: What is the name of the temporary JUPITER and HOPE-3 randomized trials?

Output: JUPITER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the temporary JUPITER and HOPE-3 randomized trials?. ### Response: JUPITER.


Instruction: When was this study published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 28, 2023.


Instruction: What was the title of the study published in 2017?

Output: Circulation. 2017;135:1979–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the study published in 2017?. ### Response: Circulation. 2017;135:1979–.


Instruction: Who is the Senior VicePresident of the Office of Science Operations?

Output: Gayle R. Whitman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Senior VicePresident of the Office of Science Operations?. ### Response: Gayle R. Whitman.


Instruction: What is Gayle R. Whitman's profession?

Output: PhD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Gayle R. Whitman's profession?. ### Response: PhD.


Instruction: Who is a Science andMedicine Advisor?

Output: Judy L. Bezanson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Science andMedicine Advisor?. ### Response: Judy L. Bezanson.


Instruction: What is the number needed to treat /H110055 calculated as?

Output: 1 /H11004absoluterisk reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the number needed to treat /H110055 calculated as?. ### Response: 1 /H11004absoluterisk reduction.


Instruction: What does the Institute of Medicine's goal for transparently sharing with patients mean?

Output: evi-dence with patients so that they can control (or more activelyparticipate in) their own decisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Institute of Medicine's goal for transparently sharing with patients mean?. ### Response: evi-dence with patients so that they can control (or more activelyparticipate in) their own decisions.


Instruction: Who can control their own decisions?

Output: patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who can control their own decisions?. ### Response: patients.


Instruction: What has been demonstrated most clearly among patients with the highest cardiovascularrisk?

Output: a beneficialeffect of revascularization on survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been demonstrated most clearly among patients with the highest cardiovascularrisk?. ### Response: a beneficialeffect of revascularization on survival.


Instruction: Traditional methods of risk stratification have relied on what?

Output: coronary anatomy and LV function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Traditional methods of risk stratification have relied on what?. ### Response: coronary anatomy and LV function.


Instruction: How can this guideline be used?

Output: otherstrategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can this guideline be used?. ### Response: otherstrategies.


Instruction: The specific anatomic features of the patient and thelikelihood of procedural success often influence the approach to a patient for whom revascularization is being considered?

Output: 412

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The specific anatomic features of the patient and thelikelihood of procedural success often influence the approach to a patient for whom revascularization is being considered?. ### Response: 412.


Instruction: What would make the risk of PCIhigh enough and the likelihood of success low enough that CABG or medical therapy would be preferred?

Output: coronary anatomic features

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would make the risk of PCIhigh enough and the likelihood of success low enough that CABG or medical therapy would be preferred?. ### Response: coronary anatomic features.


Instruction: Complete revascularization leads to better outcomes than what?

Output: incomplete revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Complete revascularization leads to better outcomes than what?. ### Response: incomplete revascularization.


Instruction: What could be preferable to PCI in patients with chronictotal occlusion?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be preferable to PCI in patients with chronictotal occlusion?. ### Response: CABG.


Instruction: What type of surgery is preferable to PCI?

Output: CABG or medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery is preferable to PCI?. ### Response: CABG or medical therapy.


Instruction: What is there no current evidence that survival is improved after a successful PCI of a chronic total occlusion?

Output: Although the technology and techniques

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there no current evidence that survival is improved after a successful PCI of a chronic total occlusion?. ### Response: Although the technology and techniques.


Instruction: Some patients with diabetes mellitus can have diffuse disease that neither CABG nor PCI is likely to produce?

Output: sustained benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some patients with diabetes mellitus can have diffuse disease that neither CABG nor PCI is likely to produce?. ### Response: sustained benefits.


Instruction: What type of disease can lead to early graft failure?

Output: diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of disease can lead to early graft failure?. ### Response: diabetes mellitus.


Instruction: What can reduce the risk of restenosis after PCI?

Output: drug-eluting stents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can reduce the risk of restenosis after PCI?. ### Response: drug-eluting stents.


Instruction: What can reduce the risk of MI after PCI?

Output: drug-eluting stents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can reduce the risk of MI after PCI?. ### Response: drug-eluting stents.


Instruction: What is DES?

Output: drug-eluting stents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DES?. ### Response: drug-eluting stents.


Instruction: How many patients with SIHD have clinical features that suggest that revascularization is unlikely to improve life expectancy?

Output: The majority

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with SIHD have clinical features that suggest that revascularization is unlikely to improve life expectancy?. ### Response: The majority.


Instruction: Antianginal therapy and intensive treatment for risk factors are recommended before consideration of what?

Output: PCI or CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Antianginal therapy and intensive treatment for risk factors are recommended before consideration of what?. ### Response: PCI or CABG.


Instruction: What is recommended before consideration of PCI or CABG to relieve symptoms?

Output: antianginal therapy and intensive treatment for risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended before consideration of PCI or CABG to relieve symptoms?. ### Response: antianginal therapy and intensive treatment for risk factors.


Instruction: What is a broad range of highly effective drugs available?

Output: beta blockers, calcium channel blockers,long-acting nitrates, and newer agents such as ranolazine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a broad range of highly effective drugs available?. ### Response: beta blockers, calcium channel blockers,long-acting nitrates, and newer agents such as ranolazine.


Instruction: What type of drugs have been shown to improve survival in patients after AMI and in patients with hypertension?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of drugs have been shown to improve survival in patients after AMI and in patients with hypertension?. ### Response: Beta blockers.


Instruction: How long does a beta blocker provide?

Output: 24-hourcoverage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does a beta blocker provide?. ### Response: 24-hourcoverage.


Instruction: What does the writing committee recommend as first-line drugs for treating angina?

Output: Beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing committee recommend as first-line drugs for treating angina?. ### Response: Beta blockers.


Instruction: What do patients after AMI and in patients with hypertension provide?

Output: 24-hourcoverage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do patients after AMI and in patients with hypertension provide?. ### Response: 24-hourcoverage.


Instruction: What indicates Class of Recommendation?

Output: COR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates Class of Recommendation?. ### Response: COR.


Instruction: What indicates Heart Failure?

Output: HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates Heart Failure?. ### Response: HF.


Instruction: Where can you find this article?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find this article?. ### Response: http://ahajournals.org.


Instruction: When was this article downloaded?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: May 3, 2023.


Instruction: What was the RR of all-cause mortality in studies with lower SBP targets?

Output: 0.93

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of all-cause mortality in studies with lower SBP targets?. ### Response: 0.93.


Instruction: What is the CI of cardiac events in low-quality evidence?

Output: 0.77 to 1.04

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CI of cardiac events in low-quality evidence?. ### Response: 0.77 to 1.04.


Instruction: In studies with higher BP targets, what was RR?

Output: relative risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In studies with higher BP targets, what was RR?. ### Response: relative risk.


Instruction: What was the ARR of the first study?

Output: 0.94

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the ARR of the first study?. ### Response: 0.94.


Instruction: What were the higher BP targets?

Output: 11–13, 20, 22, 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the higher BP targets?. ### Response: 11–13, 20, 22, 23.


Instruction: How was the difference in BP between intensive treatment and control groups?

Output: littledifference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the difference in BP between intensive treatment and control groups?. ### Response: littledifference.


Instruction: What was the original wording of the first 2 paragraphs under thatheading?

Output: “High-quality evidence showed reductions in all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the original wording of the first 2 paragraphs under thatheading?. ### Response: “High-quality evidence showed reductions in all-cause mortality.


Instruction: What was RR, 0.90 [95% CI, 0.83 to 0.98]?

Output: relative risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was RR, 0.90 [95% CI, 0.83 to 0.98]?. ### Response: relative risk.


Instruction: What was the baseline SBP for patients with a target SBP of less than 150 mm Hg (11-21)?

Output: 160 mm Hg or greater

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the baseline SBP for patients with a target SBP of less than 150 mm Hg (11-21)?. ### Response: 160 mm Hg or greater.


Instruction: What did low-quality evidence show in studies with lower SBP targets?

Output: no statistically signiﬁ-cant reduction in all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did low-quality evidence show in studies with lower SBP targets?. ### Response: no statistically signiﬁ-cant reduction in all-cause mortality.


Instruction: What did low-quality evidence show no statistically signifi-cant reduction in?

Output: all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did low-quality evidence show no statistically signifi-cant reduction in?. ### Response: all-cause mortality.


Instruction: What was the RR of studies with lower BP tar-gets?

Output: 0.79

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of studies with lower BP tar-gets?. ### Response: 0.79.


Instruction: What type of evidence showed a reduced risk forstroke?

Output: moderate-quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of evidence showed a reduced risk forstroke?. ### Response: moderate-quality.


Instruction: What was the ARR of the tar-gets?

Output: 0.94

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the ARR of the tar-gets?. ### Response: 0.94.


Instruction: What may not have been able to detect differences in clinical outcomes?

Output: these studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not have been able to detect differences in clinical outcomes?. ### Response: these studies.


Instruction: What was reduced withtreatment to 150 mm Hg?

Output: Incidence of stroke and cardiac events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reduced withtreatment to 150 mm Hg?. ### Response: Incidence of stroke and cardiac events.


Instruction: What did not have additional benefit?

Output: Treating to 140 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not have additional benefit?. ### Response: Treating to 140 mm Hg.


Instruction: What was the original wording of the article?

Output: “High-quality evidence showed reductions in all-cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the original wording of the article?. ### Response: “High-quality evidence showed reductions in all-cause mortality.


Instruction: What is the first paragraph of Recommendation 1?

Output: on page

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first paragraph of Recommendation 1?. ### Response: on page.


Instruction: What has been suggested as a possible role for craniectomy in ameliorating increased ICP caused by ICH?

Output: recent retrospective studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been suggested as a possible role for craniectomy in ameliorating increased ICP caused by ICH?. ### Response: recent retrospective studies.


Instruction: What are two underlying structural lesions that the current recommendations do not apply to?

Output: aneurysms and arteriove-nous malformations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two underlying structural lesions that the current recommendations do not apply to?. ### Response: aneurysms and arteriove-nous malformations.


Instruction: Why were structural lesions not included in the described ICH surgery trials?

Output: intracranial hemorrhage caused by trauma or underlying structural lesions such as aneurysms and arteriove-nous malformations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why were structural lesions not included in the described ICH surgery trials?. ### Response: intracranial hemorrhage caused by trauma or underlying structural lesions such as aneurysms and arteriove-nous malformations.


Instruction: What was STICH undertaken to determine?

Output: whether early surgery reduces mortality and improves neurological outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was STICH undertaken to determine?. ### Response: whether early surgery reduces mortality and improves neurological outcome.


Instruction: How does conservative management of supratentorial ICH improve neurological outcome compared with conservative management?

Output: early surgery reduces mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does conservative management of supratentorial ICH improve neurological outcome compared with conservative management?. ### Response: early surgery reduces mortality.


Instruction: When did the treating neurosurgeon determine that uncertainty of preferred?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the treating neurosurgeon determine that uncertainty of preferred?. ### Response: April 28, 2023.


Instruction: In 2008, what percentage of active duty military had HTN?

Output: 13%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 2008, what percentage of active duty military had HTN?. ### Response: 13%.


Instruction: What percentage of the general population is 20-44 years of age?

Output: HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the general population is 20-44 years of age?. ### Response: HTN.


Instruction: Along with BMI, male sex, and African American, what is an indicator of HTN in the military?

Output: increased body mass index

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Along with BMI, male sex, and African American, what is an indicator of HTN in the military?. ### Response: increased body mass index.


Instruction: BMI, male sex, and African American race were all independe ntly associated with what?

Output: HTN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BMI, male sex, and African American race were all independe ntly associated with what?. ### Response: HTN.


Instruction: What was also associated with a new diagnosis of HTN compared to active duty military not deployed?

Output: exposure to multiple stressful deployments

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was also associated with a new diagnosis of HTN compared to active duty military not deployed?. ### Response: exposure to multiple stressful deployments.


Instruction: What was the first study to compare the cardiovascular health metrics of active duty Army men and women with those of NHANES participants between 2011 and 2012?

Output: <120/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the first study to compare the cardiovascular health metrics of active duty Army men and women with those of NHANES participants between 2011 and 2012?. ### Response: <120/80 mm Hg.


Instruction: What percentage of men had an ideal blood pressure defined as 120/80 mm Hg?

Output: 27%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of men had an ideal blood pressure defined as 120/80 mm Hg?. ### Response: 27%.


Instruction: What percentage of NHANES participants were 40 years old compared to 86% of Army personnel?

Output: 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of NHANES participants were 40 years old compared to 86% of Army personnel?. ### Response: 50%.


Instruction: What percentage of Army personnel are 40 years old?

Output: 86%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of Army personnel are 40 years old?. ### Response: 86%.


Instruction: What can provide the advantages of hematoma removal with less surgical trauma and greater net benefit to patients?

Output: 231

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can provide the advantages of hematoma removal with less surgical trauma and greater net benefit to patients?. ### Response: 231.


Instruction: What is another rational but still unproven approach to acute ICH treatment?

Output: neuroprotec-tion of surrounding brain tissue from the toxic effects of the hematoma

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another rational but still unproven approach to acute ICH treatment?. ### Response: neuroprotec-tion of surrounding brain tissue from the toxic effects of the hematoma.


Instruction: The translation of biological data on neuro-protection from the toxic effects of hematoma is what?

Output: neuroprotec-tion of surrounding brain tissue from the toxic effects of the hematoma. The translation of biological data on neuro-protection from animals to human ICH patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The translation of biological data on neuro-protection from the toxic effects of hematoma is what?. ### Response: neuroprotec-tion of surrounding brain tissue from the toxic effects of the hematoma. The translation of biological data on neuro-protection from animals to human ICH patients.


Instruction: What is the hematoma?

Output: toxic effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the hematoma?. ### Response: toxic effects.


Instruction: The translation of biological data on neuro-protection from animals to human ICH patients may face the same difficulties encountered by what field?

Output: ischemic stroke neuroprotection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The translation of biological data on neuro-protection from animals to human ICH patients may face the same difficulties encountered by what field?. ### Response: ischemic stroke neuroprotection.


Instruction: Emerging methods such as prehospital administra-tion of what are emerging methods?

Output: candidate neuroprotectants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Emerging methods such as prehospital administra-tion of what are emerging methods?. ### Response: candidate neuroprotectants.


Instruction: What should increase the range of feasible treatment approaches and time windows for acute ICH?

Output: prehospital administra-tion of candidate neuroprotectants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should increase the range of feasible treatment approaches and time windows for acute ICH?. ### Response: prehospital administra-tion of candidate neuroprotectants.


Instruction: What are some of the gains seen in http://ahajournals.org?

Output: targeted treatments for acute ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the gains seen in http://ahajournals.org?. ### Response: targeted treatments for acute ICH.


Instruction: How many of the gains seen in ahajournals.org by on April 28, 2023?

Output: 326

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the gains seen in ahajournals.org by on April 28, 2023?. ### Response: 326.


Instruction: What was the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 82 of 134 Work Group?

Output: CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting March 2020 Page 82 of 134 Work Group?. ### Response: CPG.


Instruction: What was reviewed and discussed by the Work Group during each review period?

Output: All feedback submitted

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reviewed and discussed by the Work Group during each review period?. ### Response: All feedback submitted.