Instruction: What is the difference between pressure and gain in event-free life expectancy?

Output: Treatment of high blood pres-sure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between pressure and gain in event-free life expectancy?. ### Response: Treatment of high blood pres-sure.


Instruction: When was Vasc Health Risk Manag.1:163-9?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Vasc Health Risk Manag.1:163-9?. ### Response: 2005.


Instruction: What did van Dieren S, Kengne AP, Chalmers J, et al. do?

Output: Effects of blood pressure lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did van Dieren S, Kengne AP, Chalmers J, et al. do?. ### Response: Effects of blood pressure lowering.


Instruction: How many diabetes cases were there in 2012?

Output: 98:83–90. S4.4-58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many diabetes cases were there in 2012?. ### Response: 98:83–90. S4.4-58.


Instruction: What was the name of the study that examined the effects of diabetes on the development of diabetes?

Output: ACCORD randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that examined the effects of diabetes on the development of diabetes?. ### Response: ACCORD randomized trial.


Instruction: Who is a professor of medicine at the University of Milan-Bicocca?

Output: Giuseppe Mancia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a professor of medicine at the University of Milan-Bicocca?. ### Response: Giuseppe Mancia.


Instruction: Who is the Chairman of the Department of Clinical Medicine, Prevention and Applied Biotechnologies?

Output: Giuseppe ManciaContent ReviewerUniversity of Milan-Bicocca

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chairman of the Department of Clinical Medicine, Prevention and Applied Biotechnologies?. ### Response: Giuseppe ManciaContent ReviewerUniversity of Milan-Bicocca.


Instruction: Who is a content reviewer for Novartis Corporation?

Output: Andrew Miller

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a content reviewer for Novartis Corporation?. ### Response: Andrew Miller.


Instruction: Who is the director of the Einsheimer Cardiovascular Health Program?

Output: Pamela Morris

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the director of the Einsheimer Cardiovascular Health Program?. ### Response: Pamela Morris.


Instruction: What is the co-director of Amgen Inc.?

Output: Pamela MorrisContent Reviewer—Prevention Council, ChairSeinsheimer Cardiovascular Health Program— Director;Women's Heart CareMedical University of South Carolina— Co-Director•  Amgen Inc.•  AstraZeneca

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the co-director of Amgen Inc.?. ### Response: Pamela MorrisContent Reviewer—Prevention Council, ChairSeinsheimer Cardiovascular Health Program— Director;Women's Heart CareMedical University of South Carolina— Co-Director•  Amgen Inc.•  AstraZeneca.


Instruction: Who is the Co-Director of Heart CareMedical University of South Carolina?

Output: Amgen Inc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Co-Director of Heart CareMedical University of South Carolina?. ### Response: Amgen Inc.


Instruction: What is the affiliation of Martin Myers?

Output: Scientist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the affiliation of Martin Myers?. ### Response: Scientist.


Instruction: What is the name of the professor of medicine at Mayo Clinic?

Output: Judd and Mary Morris Leighton

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at Mayo Clinic?. ### Response: Judd and Mary Morris Leighton.


Instruction: Who is the director of the Cardiovascular Division at Brigham and Women's Hospital?

Output: Strategic Planning

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the director of the Cardiovascular Division at Brigham and Women's Hospital?. ### Response: Strategic Planning.


Instruction: Who is the Director of Strategic Planning at Women's Hospital?

Output: Harvard Medical School—Professor of Medicine; Brigham

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of Strategic Planning at Women's Hospital?. ### Response: Harvard Medical School—Professor of Medicine; Brigham.


Instruction: What is the name of the professor of cell, developmental and integrative biology at the University of Alabama at Birmingham?

Output: Suzanne Oparil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of cell, developmental and integrative biology at the University of Alabama at Birmingham?. ### Response: Suzanne Oparil.


Instruction: Which company is a competitor of AstraZeneca?

Output: Amgen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which company is a competitor of AstraZeneca?. ### Response: Amgen.


Instruction: What is the name of the company that is affiliated with Duke University?

Output: AstraZeneca

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the company that is affiliated with Duke University?. ### Response: AstraZeneca.


Instruction: Which company is associated with Bayer Healthcare Pharmaceuticals, Inc.?

Output: AstraZeneca

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which company is associated with Bayer Healthcare Pharmaceuticals, Inc.?. ### Response: AstraZeneca.


Instruction: Who is the Chief of Cardiovascular Medicine at Hands Hospital at University of Florida?

Output: Professor of Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chief of Cardiovascular Medicine at Hands Hospital at University of Florida?. ### Response: Professor of Medicine.


Instruction: What is Capricor?

Output: Inc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Capricor?. ### Response: Inc.


Instruction: What is Sanofi-Aventis?

Output: InVentive Health Clinical. LLC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Sanofi-Aventis?. ### Response: InVentive Health Clinical. LLC.


Instruction: Who is a professor of medicine at Case Western Reserve University School of Medicine?

Output: Mahboob Rahman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a professor of medicine at Case Western Reserve University School of Medicine?. ### Response: Mahboob Rahman.


Instruction: What is the name of the ACC/AHA Task Force on Clinical Practice Guidelines?

Output: Barbara RiegelContent Reviewer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACC/AHA Task Force on Clinical Practice Guidelines?. ### Response: Barbara RiegelContent Reviewer.


Instruction: Who is a co-investigator at NIH?

Output: mentor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a co-investigator at NIH?. ### Response: mentor.


Instruction: What is another name for Novartis Corp?

Output: Pfizer Inc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Novartis Corp?. ### Response: Pfizer Inc.


Instruction: What is the name of the company that grants grants to?

Output: Novartis Corp

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the company that grants grants to?. ### Response: Novartis Corp.


Instruction: What does the name Novartis Corp stand for?

Output: Novartis Corporation†

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the name Novartis Corp stand for?. ### Response: Novartis Corporation†.


Instruction: What is the most important limitation of systemicthrombolytic therapy?

Output: it increases bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most important limitation of systemicthrombolytic therapy?. ### Response: it increases bleeding.


Instruction: What does CDT use if there is not a high risk of bleeding?

Output: anticoagulation alone, US-assisted CDTimproved right ventricular function at 24 h.154Observational studies also suggest that CDT is effectiveat removing thrombus, lowering pulmonary arterialpressure, and improving right ventricular function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CDT use if there is not a high risk of bleeding?. ### Response: anticoagulation alone, US-assisted CDTimproved right ventricular function at 24 h.154Observational studies also suggest that CDT is effectiveat removing thrombus, lowering pulmonary arterialpressure, and improving right ventricular function.


Instruction: CDT uses alower dose of what?

Output: thrombolytic drug

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CDT uses alower dose of what?. ### Response: thrombolytic drug.


Instruction: What is expected to cause less bleeding at remote sites?

Output: CDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is expected to cause less bleeding at remote sites?. ### Response: CDT.


Instruction: What may be more effective than systemic thrombolytic therapy?

Output: CDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be more effective than systemic thrombolytic therapy?. ### Response: CDT.


Instruction: How does it achieve a high local concentration?

Output: by infusing drug directly intothe PE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does it achieve a high local concentration?. ### Response: by infusing drug directly intothe PE.


Instruction: How is thrombolytic drug infused into the PE?

Output: directly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is thrombolytic drug infused into the PE?. ### Response: directly.


Instruction: What is a result ofplacement of the infusion catheter in the thrombus or additional maneuvers?

Output: thrombus fragmentation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a result ofplacement of the infusion catheter in the thrombus or additional maneuvers?. ### Response: thrombus fragmentation.


Instruction: Thrombolytic therapy is usually infused over many hours or overnight what?

Output: emer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Thrombolytic therapy is usually infused over many hours or overnight what?. ### Response: emer.


Instruction: What is usually infused over many hours or overnight?

Output: Thrombolytic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is usually infused over many hours or overnight?. ### Response: Thrombolytic therapy.


Instruction: What can be given while systemicthrombolytic therapy is being given while CDT is being arranged?

Output: active thrombus fragmentation andaspiration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be given while systemicthrombolytic therapy is being given while CDT is being arranged?. ### Response: active thrombus fragmentation andaspiration.


Instruction: How many patients in a single randomized trial found that US-assisted CDTimproved right ventricular function at 24 h?

Output: 59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients in a single randomized trial found that US-assisted CDTimproved right ventricular function at 24 h?. ### Response: 59.


Instruction: What did US-assisted CDTimprove at 24 h?

Output: right ventricular function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did US-assisted CDTimprove at 24 h?. ### Response: right ventricular function.


Instruction: What is effective at removing thrombus, lowering pulmonary arterialpressure, and improving rightventricular function?

Output: CDT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective at removing thrombus, lowering pulmonary arterialpressure, and improving rightventricular function?. ### Response: CDT.


Instruction: How many patients were in the retrospective registry?

Output: 101

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were in the retrospective registry?. ### Response: 101.


Instruction: How many people were in a prospective cohort study?

Output: 150

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were in a prospective cohort study?. ### Response: 150.


Instruction: What evidence supports the efficacy of CDT?

Output: Observational studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What evidence supports the efficacy of CDT?. ### Response: Observational studies.


Instruction: Who noted the higher risk of r enal dysfunction for people taking MRAs?

Output: The committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who noted the higher risk of r enal dysfunction for people taking MRAs?. ### Response: The committee.


Instruction: Renal dysfunction was not included in the Irish study, but was included in what?

Output: UK study model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Renal dysfunction was not included in the Irish study, but was included in what?. ### Response: UK study model.


Instruction: What did the committee consider the associated cost of?

Output: renal dysfunction in the EMPHASIS -HF trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee consider the associated cost of?. ### Response: renal dysfunction in the EMPHASIS -HF trial.


Instruction: The EMPHASIS -HF trial reported what type of dysfunction?

Output: renal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The EMPHASIS -HF trial reported what type of dysfunction?. ### Response: renal.


Instruction: The committee considered that the cost in the UK economic analysis may have been underestimated due to what?

Output: the de finitions adopted to report renal dysfunction in the EMPHASIS -HF trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee considered that the cost in the UK economic analysis may have been underestimated due to what?. ### Response: the de finitions adopted to report renal dysfunction in the EMPHASIS -HF trial.


Instruction: What is the term for acute kidney injury?

Output: AKI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for acute kidney injury?. ### Response: AKI.


Instruction: Why did the committee recommend that MRAs be considered?

Output: higher risk of r enal dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did the committee recommend that MRAs be considered?. ### Response: higher risk of r enal dysfunction.


Instruction: When should blood monitoring be done during uptitration?

Output: first 3 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should blood monitoring be done during uptitration?. ### Response: first 3 months.


Instruction: How many monthly monitoring should be done thereafter?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many monthly monitoring should be done thereafter?. ### Response: 6.


Instruction: What was the 2010 CHF guideline called?

Output: CG108

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2010 CHF guideline called?. ### Response: CG108.


Instruction: What was a requirement of the EMPHASIS - Practical notes?

Output: Uptitration monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a requirement of the EMPHASIS - Practical notes?. ### Response: Uptitration monitoring.


Instruction: What is the name of the electrophysiologic pattern in asymptomatic patients?

Output: Wolff-Parkinson-White

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the electrophysiologic pattern in asymptomatic patients?. ### Response: Wolff-Parkinson-White.


Instruction: What is a prognostic value of electrophysiology testing?

Output: left-atrial size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prognostic value of electrophysiology testing?. ### Response: left-atrial size.


Instruction: How does the Wolff-Parkinson-White pattern affect the outcome?

Output: Prognostic value of electrophysiology testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the Wolff-Parkinson-White pattern affect the outcome?. ### Response: Prognostic value of electrophysiology testing.


Instruction: What is asymptomatic patients with the Wolff-Parkinson-White pattern?

Output: Electrophysiologic evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic patients with the Wolff-Parkinson-White pattern?. ### Response: Electrophysiologic evaluation.


Instruction: What is the Circulation. 1990;82:1718–23?

Output: Prognostic value of electrophysiology testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Circulation. 1990;82:1718–23?. ### Response: Prognostic value of electrophysiology testing.


Instruction: Milstein S, Sharma AD, Klein GJ. Electrophysiologic profile of what?

Output: asymptomatic Wolff-Parkinson-White pattern

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Milstein S, Sharma AD, Klein GJ. Electrophysiologic profile of what?. ### Response: asymptomatic Wolff-Parkinson-White pattern.


Instruction: Am J Cardiol. 1986;57:1097–100.

Output: 309

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Am J Cardiol. 1986;57:1097–100.. ### Response: 309.


Instruction: What is the Wolff-Parkinson-White pattern?

Output: electro-cardiographic pattern

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Wolff-Parkinson-White pattern?. ### Response: electro-cardiographic pattern.


Instruction: When did Pacing Clin Electrophysiol. 1989:12:413–20?

Output: 310

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Pacing Clin Electrophysiol. 1989:12:413–20?. ### Response: 310.


Instruction: What does Havránek S, Simek J, St’ovek P, et al. say about the distribution of mean cycle length in cavo-tricuspid isthmus dependent atrial flutter?

Output: Distribution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Havránek S, Simek J, St’ovek P, et al. say about the distribution of mean cycle length in cavo-tricuspid isthmus dependent atrial flutter?. ### Response: Distribution.


Instruction: What is an independent predictor of atrial fibrillation recurrence?

Output: left-atrial size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an independent predictor of atrial fibrillation recurrence?. ### Response: left-atrial size.


Instruction: What is atri-al flutter mechanisms and clinical implications?

Output: Inter-relationships of atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atri-al flutter mechanisms and clinical implications?. ### Response: Inter-relationships of atrial fibrillation.


Instruction: Atrial fibrillation recurrence.

Output: left-atrial size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Atrial fibrillation recurrence.. ### Response: left-atrial size.


Instruction: What is the J Cardiovasc Electrophysiol. 2007:18:799–802.

Output: left-atrial size as an independent predictor of atrial fibrillation recurrence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Cardiovasc Electrophysiol. 2007:18:799–802.. ### Response: left-atrial size as an independent predictor of atrial fibrillation recurrence.


Instruction: How many patients were followed up after catheter ablation of the cavotricuspid isthmus?

Output: 333

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were followed up after catheter ablation of the cavotricuspid isthmus?. ### Response: 333.


Instruction: What is a risk prediction for recurrent arrhythmias?

Output: Long-term outcome of radiofrequen-cy catheter ablation for typical atrial flutter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk prediction for recurrent arrhythmias?. ### Response: Long-term outcome of radiofrequen-cy catheter ablation for typical atrial flutter.


Instruction: What is the risk of atrial fibrillation after radiofrequency ablation of type I atrial flutter?

Output: time to onset, determinants, and clinical course. Circulation. 1998;98:315–22. 316. Chinitz JS, Gerstenfeld EP, Marchlinski FE, et al. Atrial fibrillation is common

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of atrial fibrillation after radiofrequency ablation of type I atrial flutter?. ### Response: time to onset, determinants, and clinical course. Circulation. 1998;98:315–22. 316. Chinitz JS, Gerstenfeld EP, Marchlinski FE, et al. Atrial fibrillation is common.


Instruction: What is common after ablation of isolated atrial flutter during long-term follow-up?

Output: Atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is common after ablation of isolated atrial flutter during long-term follow-up?. ### Response: Atrial fibrillation.


Instruction: What is the time to onset, determinants, and clinical course after radiofrequency ablation?

Output: Atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the time to onset, determinants, and clinical course after radiofrequency ablation?. ### Response: Atrial fibrillation.


Instruction: What is the cause of atrial flutter?

Output: drug

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of atrial flutter?. ### Response: drug.


Instruction: What is amiodarone therapy used for?

Output: paroxysmal atrial fibrillation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is amiodarone therapy used for?. ### Response: paroxysmal atrial fibrillation.


Instruction: When was the Eur Heart J 21:565–72 published?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur Heart J 21:565–72 published?. ### Response: 2000.


Instruction: What is a pre-dictors of atrial fibrillation occurrence after transisthmic ablation in pa-tients with preablation lone atrial flutter?

Output: coexistent atrial fibrillation, and drug induced atrial flutter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pre-dictors of atrial fibrillation occurrence after transisthmic ablation in pa-tients with preablation lone atrial flutter?. ### Response: coexistent atrial fibrillation, and drug induced atrial flutter.


Instruction: What is the pacing Clin Electrophysiol. 2004;27:1507–12. 319 Satomi K, Chun KRJ, Tilz R, et al. Catheter ablation of what within the right atrium free wall?

Output: multiple un-stable macroreentrant tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pacing Clin Electrophysiol. 2004;27:1507–12. 319 Satomi K, Chun KRJ, Tilz R, et al. Catheter ablation of what within the right atrium free wall?. ### Response: multiple un-stable macroreentrant tachycardia.


Instruction: What causes multiple un-stable macroreentrant tachycardia within the right atrium free wall?

Output: Catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes multiple un-stable macroreentrant tachycardia within the right atrium free wall?. ### Response: Catheter ablation.


Instruction: What does Circ Arrhythm Electrophysiol. 2010:3:24–31?

Output: 320

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Circ Arrhythm Electrophysiol. 2010:3:24–31?. ### Response: 320.


Instruction: What was not significantly increased with ticagrelor compared with clopidogrel?

Output: CABG-related bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not significantly increased with ticagrelor compared with clopidogrel?. ### Response: CABG-related bleeding.


Instruction: What was associated with higher rates of transient dyspnea and bradycardia com-pared with the other drugs?

Output: Ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with higher rates of transient dyspnea and bradycardia com-pared with the other drugs?. ### Response: Ticagrelor.


Instruction: How was the reduction in vascular mortality and all-cause mortality observed?

Output: 568

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the reduction in vascular mortality and all-cause mortality observed?. ### Response: 568.


Instruction: How many patients discontinued clopidogrel because of dyspnea?

Output: only a very small percentage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients discontinued clopidogrel because of dyspnea?. ### Response: only a very small percentage.


Instruction: What is a black box warning about?

Output: maintenance doses of aspirin above 100 mg reducethe effectiveness of ticagrelor and should be avoided

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a black box warning about?. ### Response: maintenance doses of aspirin above 100 mg reducethe effectiveness of ticagrelor and should be avoided.


Instruction: What should maintenance doses of aspirin above 100 mg reduce the effectiveness of?

Output: ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should maintenance doses of aspirin above 100 mg reduce the effectiveness of?. ### Response: ticagrelor.


Instruction: What should be used after an initial dose of ticagrelor?

Output: aspirin 75 mgto 100 mg per day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used after an initial dose of ticagrelor?. ### Response: aspirin 75 mgto 100 mg per day.


Instruction: How often should patients be given a twice-daily dosing and reversible dose of the drug?

Output: compliance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often should patients be given a twice-daily dosing and reversible dose of the drug?. ### Response: compliance.


Instruction: Ti-cagrelor has not been studied in what type of PCI?

Output: elective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ti-cagrelor has not been studied in what type of PCI?. ### Response: elective.


Instruction: What type of therapy is recommended in patients undergoing primary PCI treated withUFH?

Output: GP IIb/IIIainhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is recommended in patients undergoing primary PCI treated withUFH?. ### Response: GP IIb/IIIainhibitor.


Instruction: What is a GP IIb/IIIainhibitor?

Output: abciximab, double-bolus eptifibatide, orhigh-bolus dose tirofiban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a GP IIb/IIIainhibitor?. ### Response: abciximab, double-bolus eptifibatide, orhigh-bolus dose tirofiban.


Instruction: What is another name for a double-bolus eptifibatide?

Output: high-bolus dose tirofiban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for a double-bolus eptifibatide?. ### Response: high-bolus dose tirofiban.


Instruction: What is the Level of Evidence for GPIIb/IIIa inhibitor administration in patients pretreated with clopidogrel?

Output: C)Class IIb1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence for GPIIb/IIIa inhibitor administration in patients pretreated with clopidogrel?. ### Response: C)Class IIb1.


Instruction: What is a level of evidence for GP IIb andIIIa in patients undergoing primary PCI with abcix-imab?

Output: 616,619

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a level of evidence for GP IIb andIIIa in patients undergoing primary PCI with abcix-imab?. ### Response: 616,619.


Instruction: What is notbeneficial for patients with STEMI undergoing PCI?

Output: Routine precatheterization laboratory (eg, ambu-lance or emergency department) administration ofGP IIb/IIIa inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is notbeneficial for patients with STEMI undergoing PCI?. ### Response: Routine precatheterization laboratory (eg, ambu-lance or emergency department) administration ofGP IIb/IIIa inhibitors.


Instruction: What is used in UA/NSTEMI patients with high-risk features?

Output: it isuseful at the time of PCI to administer a GP IIb/IIIainhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used in UA/NSTEMI patients with high-risk features?. ### Response: it isuseful at the time of PCI to administer a GP IIb/IIIainhibitor.


Instruction: What is another name for a GP IIb/IIIainhibitor?

Output: high-bolus dose tirofiban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for a GP IIb/IIIainhibitor?. ### Response: high-bolus dose tirofiban.


Instruction: What is a class IIa1 inhibitor in UA/NSTEMI?

Output: SIHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class IIa1 inhibitor in UA/NSTEMI?. ### Response: SIHD.


Instruction: What is an example of a feature treated with UFH and ade-quately pretreated with clopidogrel?

Output: elevated troponin level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a feature treated with UFH and ade-quately pretreated with clopidogrel?. ### Response: elevated troponin level.


Instruction: What is a reasonable at the time of PCI to administer a GP IIb/IIIa inhibitor?

Output: In UA/NSTEMI patients with high-risk features

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reasonable at the time of PCI to administer a GP IIb/IIIa inhibitor?. ### Response: In UA/NSTEMI patients with high-risk features.


Instruction: What was reworded for clarity from 2014 Secondary Prevention?

Output: I C-EORecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reworded for clarity from 2014 Secondary Prevention?. ### Response: I C-EORecommendation.


Instruction: What was the original wording of the I C-EORecommendation?

Output: COR unchanged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the original wording of the I C-EORecommendation?. ### Response: COR unchanged.


Instruction: How was the LOE amended to conform with ACC/AHA 2015?

Output: COR unchanged. LOE amended to conform with ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the LOE amended to conform with ACC/AHA 2015?. ### Response: COR unchanged. LOE amended to conform with ACC/AHA 2015 Recommendation Classification System.


Instruction: What is another term for secondhand tobacco smoke?

Output: passive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for secondhand tobacco smoke?. ### Response: passive.


Instruction: What year was the IIa B-NRRecommendation reworded for clarity?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the IIa B-NRRecommendation reworded for clarity?. ### Response: 2014.


Instruction: What might be considered in-hospital initiation of varenicline to promote smoking cessation?

Output: smokers with an AIS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What might be considered in-hospital initiation of varenicline to promote smoking cessation?. ### Response: smokers with an AIS.


Instruction: What 2012 meta-analysis by the Cochrane group indicates that high-intensity behavioral interventions that begin during an index hospitalization and include at least 1 month of supportive contact after discharge increased smoking cesation rates after discharge?

Output: 2012 meta-analysis by the Cochrane group indicates that high-intensity behavioral interventions that begin during an index hospitalization and include at least 1 month of supportive contact after discharge increased smoking cessation rates after discharge (RR, 1.37

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What 2012 meta-analysis by the Cochrane group indicates that high-intensity behavioral interventions that begin during an index hospitalization and include at least 1 month of supportive contact after discharge increased smoking cesation rates after discharge?. ### Response: 2012 meta-analysis by the Cochrane group indicates that high-intensity behavioral interventions that begin during an index hospitalization and include at least 1 month of supportive contact after discharge increased smoking cessation rates after discharge (RR, 1.37.


Instruction: What increased smoking cessation rates after discharge?

Output: high-intensity behavioral interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What increased smoking cessation rates after discharge?. ### Response: high-intensity behavioral interventions.


Instruction: What was the RR for each level of intervention intensity among patients with a cardiovascular diagnosis?

Output: 1.42

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR for each level of intervention intensity among patients with a cardiovascular diagnosis?. ### Response: 1.42.


Instruction: How many smokers hospitalized with an acute coronary syndrome were randomized to varenicline or bupropion in a 2016 multicenter, double-blind, placebo controlled trial?

Output: 302

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many smokers hospitalized with an acute coronary syndrome were randomized to varenicline or bupropion in a 2016 multicenter, double-blind, placebo controlled trial?. ### Response: 302.


Instruction: What was the abstinence rate in the varenicline group compared to the placebo group?

Output: 47.3%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the abstinence rate in the varenicline group compared to the placebo group?. ### Response: 47.3%.


Instruction: How much was the continuous abstainance rate in varenicaline compared with the placebo?

Output: 35.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the continuous abstainance rate in varenicaline compared with the placebo?. ### Response: 35.8%.


Instruction: What were patients randomized to for 12 weeks with an acute coronary syndrome?

Output: varenicline or placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were patients randomized to for 12 weeks with an acute coronary syndrome?. ### Response: varenicline or placebo.


Instruction: What percentage of patients received low-intensity counseling in the varenicline group versus 25.8% in the placebo group?

Output: 393

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients received low-intensity counseling in the varenicline group versus 25.8% in the placebo group?. ### Response: 393.


Instruction: How many patients in both groups received low intensity counseling?

Output: 393

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients in both groups received low intensity counseling?. ### Response: 393.


Instruction: When did the data be downloaded from http://ahajournals.org?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the data be downloaded from http://ahajournals.org?. ### Response: April 28, 2023.


Instruction: What is the name of the Systolic Hypertension in the Elderly Program?

Output: SHEP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Systolic Hypertension in the Elderly Program?. ### Response: SHEP.


Instruction: Who is responsible for the major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor?

Output: ALLHAT Officers and Coordinators for the ALLHAT CollaborativeResearch Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is responsible for the major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor?. ### Response: ALLHAT Officers and Coordinators for the ALLHAT CollaborativeResearch Group.


Instruction: What are the major outcomes in high-risk hypertensive patientsrandomized to angiotensin-converting enzyme inhibitor or calciumchannel blocker vs diuretic?

Output: Antihypertensive and Lipid-LoweringTreatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the major outcomes in high-risk hypertensive patientsrandomized to angiotensin-converting enzyme inhibitor or calciumchannel blocker vs diuretic?. ### Response: Antihypertensive and Lipid-LoweringTreatment to Prevent Heart Attack Trial.


Instruction: What is the name of the Antihypertensic and Lipid-LoweringTreatment to Prevent Heart Attack Trial?

Output: ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Antihypertensic and Lipid-LoweringTreatment to Prevent Heart Attack Trial?. ### Response: ALLHAT.


Instruction: What does weight reduction have on bloodlipids and lipoproteins?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does weight reduction have on bloodlipids and lipoproteins?. ### Response: Effects.


Instruction: What is the name of the meta-analysis that examined the effects of weight reduction?

Output: DELTAStudy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis that examined the effects of weight reduction?. ### Response: DELTAStudy.


Instruction: When was the Am J Clin Nutr.56:320–328.20?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Clin Nutr.56:320–328.20?. ### Response: 1992.


Instruction: What is statintherapy after acute coronary syndrome?

Output: moderate lipid-lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is statintherapy after acute coronary syndrome?. ### Response: moderate lipid-lowering.


Instruction: What is the name of the PROVE IT-TIMI 22 trial?

Output: Pravastatin or Atorvastatin Evaluation and Infection Therapy-Throm-bolysis In Myocardial Infarction 22

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PROVE IT-TIMI 22 trial?. ### Response: Pravastatin or Atorvastatin Evaluation and Infection Therapy-Throm-bolysis In Myocardial Infarction 22.


Instruction: When did J Am Coll Cardiol. 2009;54:2358–2362.21?

Output: the PROVE IT-TIMI 22(Pravastatin or Atorvastatin Evaluation and Infection Therapy-Throm-bolysis In Myocardial Infarction 22) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2009;54:2358–2362.21?. ### Response: the PROVE IT-TIMI 22(Pravastatin or Atorvastatin Evaluation and Infection Therapy-Throm-bolysis In Myocardial Infarction 22) trial.


Instruction: What does reducing dietary saturated fattyacids have on plasma lipids and lipoproteins in healthy subjects?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does reducing dietary saturated fattyacids have on plasma lipids and lipoproteins in healthy subjects?. ### Response: Effects.


Instruction: What did the DELTAStudy, protocol 1 do?

Output: Effects of reducing dietary saturated fattyacids on plasma lipids and lipoproteins in healthy subjects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the DELTAStudy, protocol 1 do?. ### Response: Effects of reducing dietary saturated fattyacids on plasma lipids and lipoproteins in healthy subjects.


Instruction: When was the Arterioscler Thromb Vasc Biol 18:441–449.22 published?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Arterioscler Thromb Vasc Biol 18:441–449.22 published?. ### Response: 1998.


Instruction: What is individualvariability in lipoprotein cholesterol response to National CholesterolEducation Program Step 2 diets?

Output: Efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is individualvariability in lipoprotein cholesterol response to National CholesterolEducation Program Step 2 diets?. ### Response: Efficacy.


Instruction: Schaefer EJ, Lichtenstein AH, Lamon-Fava S, Contois JH, Li Z, Ras-mussen H, McNamara JR, Ordovas JM, Clevidence BA,Judd JT, Goldin BR, Woods M, Gorbach S. What is the name of the program that focuses on lipolipid cholesterol

Output: lipoprotein cholesterol response to National CholesterolEducation Program Step 2 diets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Schaefer EJ, Lichtenstein AH, Lamon-Fava S, Contois JH, Li Z, Ras-mussen H, McNamara JR, Ordovas JM, Clevidence BA,Judd JT, Goldin BR, Woods M, Gorbach S. What is the name of the program that focuses on lipolipid cholesterol. ### Response: lipoprotein cholesterol response to National CholesterolEducation Program Step 2 diets.


Instruction: What does the National Choles-terol Education Program Step 2 diet do for middle-aged and elderly men and women?

Output: Efficacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the National Choles-terol Education Program Step 2 diet do for middle-aged and elderly men and women?. ### Response: Efficacy.


Instruction: What is the name of the step 2 diet?

Output: National Choles-terol Education Program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the step 2 diet?. ### Response: National Choles-terol Education Program.


Instruction: When did ArteriosclerThromb Vasc Biol. 1995;15:1079–1085.24?

Output: 1995;15:1079–1085.24. Yu-Poth S, Zhao G, Etherton T, Naglak M, Jonnalagadda S, Kris-Etherton PM. Effects of the National Cholesterol Education Program’sStep I and Step II dietary intervention programs on cardiovasculardisease risk factors: a meta-analysis. Am J Clin Nutr. 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did ArteriosclerThromb Vasc Biol. 1995;15:1079–1085.24?. ### Response: 1995;15:1079–1085.24. Yu-Poth S, Zhao G, Etherton T, Naglak M, Jonnalagadda S, Kris-Etherton PM. Effects of the National Cholesterol Education Program’sStep I and Step II dietary intervention programs on cardiovasculardisease risk factors: a meta-analysis. Am J Clin Nutr. 1999.


Instruction: What did the National Cholesterol Education Program'sStep I and Step II dietary intervention programs do?

Output: cardiovasculardisease risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the National Cholesterol Education Program'sStep I and Step II dietary intervention programs do?. ### Response: cardiovasculardisease risk factors.


Instruction: What was the name of the MRC/BHF Heart Protection Study Collaborative Group?

Output: MRC/BHFHeart Protection Study of cholesterol lowering with simvastatin in20,536 high-risk individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the MRC/BHF Heart Protection Study Collaborative Group?. ### Response: MRC/BHFHeart Protection Study of cholesterol lowering with simvastatin in20,536 high-risk individuals.


Instruction: How many high-risk individuals were enrolled in a randomised placebo-controlled trial?

Output: 20,536

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many high-risk individuals were enrolled in a randomised placebo-controlled trial?. ### Response: 20,536.


Instruction: How many high-risk individuals were treated with simvastatin in a trial?

Output: 20,536

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many high-risk individuals were treated with simvastatin in a trial?. ### Response: 20,536.


Instruction: What is the name of the trial in which simvastin was used?

Output: MRC/BHFHeart Protection Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial in which simvastin was used?. ### Response: MRC/BHFHeart Protection Study.


Instruction: When was the Lancet Journal published?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet Journal published?. ### Response: 2002.


Instruction: What is atorva-statin used for in patients with stable coronary disease?

Output: Intensive lipid lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atorva-statin used for in patients with stable coronary disease?. ### Response: Intensive lipid lowering.


Instruction: When did N Engl J Med issue 352:1425-1435?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 352:1425-1435?. ### Response: 2005.


Instruction: What is the process by which patients assume control of their health-related behaviors?

Output: Self-management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the process by which patients assume control of their health-related behaviors?. ### Response: Self-management.


Instruction: Patients decide what they will eat, if they will exercise, and what medication they will take?

Output: 342

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients decide what they will eat, if they will exercise, and what medication they will take?. ### Response: 342.


Instruction: What do CR programs play an integral role in?

Output: education and transitioning patients to adopt health-related behaviors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do CR programs play an integral role in?. ### Response: education and transitioning patients to adopt health-related behaviors.


Instruction: What can CR personnel act as?

Output: health coaches

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can CR personnel act as?. ### Response: health coaches.


Instruction: What does REACH stand for?

Output: Reduction of Atherothrombosis for Continued Health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does REACH stand for?. ### Response: Reduction of Atherothrombosis for Continued Health.


Instruction: What is the goal of the REACH registry?

Output: Reduction of Atherothrombosis for Continued Health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of the REACH registry?. ### Response: Reduction of Atherothrombosis for Continued Health.


Instruction: When secondary prevention goals are not met at 1 year, the incidence of adverse cardio-vascular events increases regardless of the number of risk factors present at baseline?

Output: 342–346The Reduction of Atherothrombosis for Continued Health (REACH) international registry reported that among patients who have undergone CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When secondary prevention goals are not met at 1 year, the incidence of adverse cardio-vascular events increases regardless of the number of risk factors present at baseline?. ### Response: 342–346The Reduction of Atherothrombosis for Continued Health (REACH) international registry reported that among patients who have undergone CABG.


Instruction: What highlights the importance of CR programs to help patients achieve their goals?

Output: The Reduction of Atherothrombosis for Continued Health (REACH) international registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What highlights the importance of CR programs to help patients achieve their goals?. ### Response: The Reduction of Atherothrombosis for Continued Health (REACH) international registry.


Instruction: What are some barriers to the adoption of preventive therapies?

Output: knowledge defi-cit, ambivalence, comorbidities, preconceived beliefs, lack of support, employment, and readiness for change

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some barriers to the adoption of preventive therapies?. ### Response: knowledge defi-cit, ambivalence, comorbidities, preconceived beliefs, lack of support, employment, and readiness for change.


Instruction: How are older patients with comorbidities who live alone more likely to remain sedentary after 1 year?

Output: poor medication and diet compliance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are older patients with comorbidities who live alone more likely to remain sedentary after 1 year?. ### Response: poor medication and diet compliance.


Instruction: Who are more likely after 1 year to remain sedentary and have poor medication and diet compliance?

Output: older patients with comorbidities who live alone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who are more likely after 1 year to remain sedentary and have poor medication and diet compliance?. ### Response: older patients with comorbidities who live alone.


Instruction: What should be individualized to meet specific sex concerns?

Output: Interventions for self-management of risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be individualized to meet specific sex concerns?. ### Response: Interventions for self-management of risk factors.


Instruction: Women in par ticular have difficulty with self-management of heart disease because of fatigue, anxiety, and depression?

Output: feel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Women in par ticular have difficulty with self-management of heart disease because of fatigue, anxiety, and depression?. ### Response: feel.


Instruction: What causes heart disease?

Output: fatigue, anxiety, and depression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes heart disease?. ### Response: fatigue, anxiety, and depression.


Instruction: What percentage of women are no longer exercising 3 months after discharge from CR?

Output: 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of women are no longer exercising 3 months after discharge from CR?. ### Response: 35%.


Instruction: Men experience different barriers to what?

Output: secondary prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Men experience different barriers to what?. ### Response: secondary prevention.


Instruction: What are some of the obstacles to compliance among men?

Output: comprehension of disease, dietary barriers (depen-dence on others for meals), and activity barriers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the obstacles to compliance among men?. ### Response: comprehension of disease, dietary barriers (depen-dence on others for meals), and activity barriers.


Instruction: What is an example of an activity that supersedes CR?

Output: employment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an activity that supersedes CR?. ### Response: employment.


Instruction: What does a hospital-based outpatient CR program compared to a home-based program help improve for both men and women?

Output: exer -cise adherence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a hospital-based outpatient CR program compared to a home-based program help improve for both men and women?. ### Response: exer -cise adherence.


Instruction: What does continuing the secondary prevention education after discharge from CR do?

Output: improve adherence to long-term self-management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does continuing the secondary prevention education after discharge from CR do?. ### Response: improve adherence to long-term self-management.


Instruction: How can prevention education after discharge from CR improve adherence to long-term self-management?

Output: Continuation of the secondary prevention education

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can prevention education after discharge from CR improve adherence to long-term self-management?. ### Response: Continuation of the secondary prevention education.


Instruction: Secondary prevention programs should be individualized, considering what?

Output: the patient’s knowledge deficit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Secondary prevention programs should be individualized, considering what?. ### Response: the patient’s knowledge deficit.


Instruction: What is a comparison of patent foramen ovale and thoracic aortic atherosclerosis in patients with cryptogenic ischemic stroke undergoing transesophageal echocardiography?

Output: frequencies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a comparison of patent foramen ovale and thoracic aortic atherosclerosis in patients with cryptogenic ischemic stroke undergoing transesophageal echocardiography?. ### Response: frequencies.


Instruction: What is the name of the study that compares patent foram ovale with the thoracic atherosclerosis in cryptogenic stroke?

Output: CLOSURE I Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares patent foram ovale with the thoracic atherosclerosis in cryptogenic stroke?. ### Response: CLOSURE I Investigators.


Instruction: What is a meta-analysis of case-control studies?

Output: Interatrial septal abnormalities and stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of case-control studies?. ### Response: Interatrial septal abnormalities and stroke.


Instruction: What is the name of the organization that is responsible for percutaneous device closure of patent fora-men ovale for stroke?

Output: American College of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that is responsible for percutaneous device closure of patent fora-men ovale for stroke?. ### Response: American College of Cardiology Foundation.


Instruction: What is the purpose of percutaneous device closure of patent fora-men ovale for secondary stroke prevention?

Output: a call for completion of randomized clinical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of percutaneous device closure of patent fora-men ovale for secondary stroke prevention?. ### Response: a call for completion of randomized clinical trials.


Instruction: What is a call for completion of randomized clinical trials?

Output: Percutaneous device closure of patent fora-men ovale for secondary stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a call for completion of randomized clinical trials?. ### Response: Percutaneous device closure of patent fora-men ovale for secondary stroke prevention.


Instruction: What is patent fora-men ovale and cryptogenic stroke in older patients?

Output: medical therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is patent fora-men ovale and cryptogenic stroke in older patients?. ### Response: medical therapy.


Instruction: What is N Engl J Med 2007357:2262–2268?

Output: Patent fora-men ovale and cryptogenic stroke in older patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is N Engl J Med 2007357:2262–2268?. ### Response: Patent fora-men ovale and cryptogenic stroke in older patients.


Instruction: What is a patent foramen ovale?

Output: Percutaneous closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a patent foramen ovale?. ### Response: Percutaneous closure.


Instruction: What is the name of the study that compared patents for a menopause and patents?

Output: PC Trial Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compared patents for a menopause and patents?. ### Response: PC Trial Investigators.


Instruction: How many patents were examined in the 2006 study?

Output: 490

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patents were examined in the 2006 study?. ### Response: 490.


Instruction: What is asymptomatic in patent foramen ovale patients?

Output: stroke or transient ischemic attack

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic in patent foramen ovale patients?. ### Response: stroke or transient ischemic attack.


Instruction: What are symptomatic patients with stroke or transient ischemic attack classified as?

Output: asymptomatic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are symptomatic patients with stroke or transient ischemic attack classified as?. ### Response: asymptomatic.


Instruction: When did the Am J Cardiol. 2009,103,124-129.491 occur?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Am J Cardiol. 2009,103,124-129.491 occur?. ### Response: 2011.


Instruction: What is the name of the study group that studies patent foramen ovale and atrial septal aneurysm?

Output: ysm Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studies patent foramen ovale and atrial septal aneurysm?. ### Response: ysm Study Group.


Instruction: What are the recurrent cerebrovascular events associated with?

Output: patent foramen ovale, atrial septal aneurysm, or both

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recurrent cerebrovascular events associated with?. ### Response: patent foramen ovale, atrial septal aneurysm, or both.


Instruction: When was the N Engl J Med 345:1740-1746?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 345:1740-1746?. ### Response: 2001.


Instruction: What is the name of the disease that is associated with patent foramen ovale?

Output: cryptogenic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that is associated with patent foramen ovale?. ### Response: cryptogenic stroke.


Instruction: What is another name for subclini-cal cerebrovascular disease?

Output: Patent foramen ovale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for subclini-cal cerebrovascular disease?. ### Response: Patent foramen ovale.


Instruction: In what year was the J Am Coll Cardiol 62:35–41?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the J Am Coll Cardiol 62:35–41?. ### Response: 2013.


Instruction: What type of stroke is closed or medical therapy for?

Output: cryptogenic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stroke is closed or medical therapy for?. ### Response: cryptogenic.


Instruction: What is the name of the group that investigated cryptogenic stroke?

Output: CLOSURE I Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that investigated cryptogenic stroke?. ### Response: CLOSURE I Investigators.


Instruction: When was the N Engl J Med 366:991-999?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 366:991-999?. ### Response: 2012.


Instruction: What is the name of the study that investigated the closure of patent foramen ovale in cryptogenic embolism?

Output: PC Trial Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the closure of patent foramen ovale in cryptogenic embolism?. ### Response: PC Trial Investigators.


Instruction: What is another name for the study?

Output: PC Trial Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the study?. ### Response: PC Trial Investigators.


Instruction: How many years was the N Engl J Med 368?

Output: 495

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years was the N Engl J Med 368?. ### Response: 495.


Instruction: What is the name of the group that investigated the possibility of closure of patent foramen ovale versus medical therapy after cryptogenic stroke?

Output: CLOSURE I Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that investigated the possibility of closure of patent foramen ovale versus medical therapy after cryptogenic stroke?. ### Response: CLOSURE I Investigators.


Instruction: What year did N Engl J Med issue 368:1092–1100?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med issue 368:1092–1100?. ### Response: 2013.


Instruction: What are saccharide and tetrasaccharide fragments?

Output: Semin Thromb Hemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are saccharide and tetrasaccharide fragments?. ### Response: Semin Thromb Hemost.


Instruction: When was Semin Thromb Hemost published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Semin Thromb Hemost published?. ### Response: 2008.


Instruction: What residues contribute to the heparin-induced conformational change in antithrombin III?

Output: 3-O- and 6-O-sulfated glucosamine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What residues contribute to the heparin-induced conformational change in antithrombin III?. ### Response: 3-O- and 6-O-sulfated glucosamine.


Instruction: How many ( 20): 6454?

Output: 26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 20): 6454?. ### Response: 26.


Instruction: How many days were there in 1987?

Output: 6454 - 6461

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days were there in 1987?. ### Response: 6454 - 6461.


Instruction: What was the total number of days in 1987 in total?

Output: 6454 - 6461

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the total number of days in 1987 in total?. ### Response: 6454 - 6461.


Instruction: Anti-Xa monitoring: inter-assay variability?

Output: Thromb Haemost

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anti-Xa monitoring: inter-assay variability?. ### Response: Thromb Haemost.


Instruction: Thromb Haemost. 2000 ; 84 ( 6 ): 1122 - 1123.

Output: Anti-Xa monitoring: inter-assay variability .   Thromb Haemost  .   2000 ; 84 ( 6 ): 1122 - 1123 .      197

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Thromb Haemost. 2000 ; 84 ( 6 ): 1122 - 1123.. ### Response: Anti-Xa monitoring: inter-assay variability .   Thromb Haemost  .   2000 ; 84 ( 6 ): 1122 - 1123 .      197.


Instruction: Kitchen S, Iampietro

Output: Kitchen   S ,  Iampietro   R

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kitchen S, Iampietro. ### Response: Kitchen   S ,  Iampietro   R.


Instruction: What drug is used to monitor anti Xa during treatment with low molecular weight heparin or danaparoid?

Output: fonda-parinux

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used to monitor anti Xa during treatment with low molecular weight heparin or danaparoid?. ### Response: fonda-parinux.


Instruction: When was Thromb Haemost tested?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Thromb Haemost tested?. ### Response: 2008.


Instruction: What is the name of the Thromb Haemost?

Output: Thromb Haemost  .  2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Thromb Haemost?. ### Response: Thromb Haemost  .  2008.


Instruction: How many ( 4 ): 1289 - 1293?

Output: 82

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 4 ): 1289 - 1293?. ### Response: 82.


Instruction: What are the names of the authors?

Output: Rota   E ,  Bazzan   M ,  Fantino   G .  Fondaparinux-related throm-bocytopenia in a previous low-molecular-weight heparin (LMWH)-induced heparin-induced thrombocytopenia (HIT) .   Thromb Haemost  .  2008 ; 99 ( 4 ): 779 - 781 .   © 2012 American College of Chest Physicians by Kimberly Henricks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors?. ### Response: Rota   E ,  Bazzan   M ,  Fantino   G .  Fondaparinux-related throm-bocytopenia in a previous low-molecular-weight heparin (LMWH)-induced heparin-induced thrombocytopenia (HIT) .   Thromb Haemost  .  2008 ; 99 ( 4 ): 779 - 781 .   © 2012 American College of Chest Physicians by Kimberly Henricks.


Instruction: What is the name of the natural pentasaccharide?

Output: SR90107/Org31540

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the natural pentasaccharide?. ### Response: SR90107/Org31540.


Instruction: In what year did Thromb Haemost occur?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Thromb Haemost occur?. ### Response: 2008.


Instruction: How many ( 6 ): 1468 - 1473?

Output: 74

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 6 ): 1468 - 1473?. ### Response: 74.


Instruction: When did Donat F, Duret JP, Santoni A, et al. study fondaparinux sodium in healthy volunteers?

Output: 1468 - 1473

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Donat F, Duret JP, Santoni A, et al. study fondaparinux sodium in healthy volunteers?. ### Response: 1468 - 1473.


Instruction: How many healthy volunteers did Clin Pharmacokinet have in 2002?

Output: 200

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many healthy volunteers did Clin Pharmacokinet have in 2002?. ### Response: 200.


Instruction: How many (suppl 2 ): 1-9. 200?

Output: 41

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many (suppl 2 ): 1-9. 200?. ### Response: 41.


Instruction: Donat F, et al. Fondaparinux sodium is not metabolised in what?

Output: mammalian liver fractions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Donat F, et al. Fondaparinux sodium is not metabolised in what?. ### Response: mammalian liver fractions.


Instruction: What does not inhibit cytochrome P450-mediated metabolism of con-comitant drugs?

Output: Fondaparinux sodium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not inhibit cytochrome P450-mediated metabolism of con-comitant drugs?. ### Response: Fondaparinux sodium.


Instruction: 41 ( suppl 2 ): 19 - what?

Output: 26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 41 ( suppl 2 ): 19 - what?. ### Response: 26.


Instruction: What is Fondaparinux sodium mechanism of action?

Output: identiﬁ  cation of speciﬁ  c binding to puriﬁ  ed and human plasma-derived proteins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Fondaparinux sodium mechanism of action?. ### Response: identiﬁ  cation of speciﬁ  c binding to puriﬁ  ed and human plasma-derived proteins.


Instruction: Fondaparinux sodium mechanism of action: identifi cation of what type of binding to human plasma-derived proteins?

Output: speci

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fondaparinux sodium mechanism of action: identifi cation of what type of binding to human plasma-derived proteins?. ### Response: speci.


Instruction: Clin Pharmacokinet. 2002 ; 41 (suppl 2 ): 11 - 18.

Output: Clin Pharmacokinet  .  2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Clin Pharmacokinet. 2002 ; 41 (suppl 2 ): 11 - 18.. ### Response: Clin Pharmacokinet  .  2002.


Instruction: How does recombinant factor VIIa reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers?

Output: Ability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does recombinant factor VIIa reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers?. ### Response: Ability.


Instruction: What is the effect of fondaparinux in healthy volunteers?

Output: pharmacoki-netics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of fondaparinux in healthy volunteers?. ### Response: pharmacoki-netics.


Instruction: How many ( 20): 2550 - 2554?

Output: 106

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ( 20): 2550 - 2554?. ### Response: 106.


Instruction: What is the effect of fonda-parinux on platelet activation in the presence of heparin-dependent antibodies?

Output: a blinded comparative multicenter study with unfractionated heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of fonda-parinux on platelet activation in the presence of heparin-dependent antibodies?. ### Response: a blinded comparative multicenter study with unfractionated heparin.


Instruction: Blood. 2005 ; 105 ( 1 ): 139 - what?

Output: 144

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood. 2005 ; 105 ( 1 ): 139 - what?. ### Response: 144.


Instruction: What is LMWH?

Output: low-molecular-weight heparin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LMWH?. ### Response: low-molecular-weight heparin.


Instruction: What is HIT?

Output: heparin-induced thrombocytopenia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HIT?. ### Response: heparin-induced thrombocytopenia.


Instruction: When was the American College of Chest Physicians founded?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the American College of Chest Physicians founded?. ### Response: 2012.


Instruction: Who published the 2019 Guidelines for Management of AIS e417 455?

Output: Powers et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 Guidelines for Management of AIS e417 455?. ### Response: Powers et al.


Instruction: What is the name of the meta-analysis that evaluated the efficacy and safety of citalopram in treating post stroke depression?

Output: Powers et al  2019 Guidelines for Management of AIS  e417 485. Tan S, Huang X, Ding L, Hong H. Efficacy and safety of citalopram in treating post-stroke depression: a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis that evaluated the efficacy and safety of citalopram in treating post stroke depression?. ### Response: Powers et al  2019 Guidelines for Management of AIS  e417 485. Tan S, Huang X, Ding L, Hong H. Efficacy and safety of citalopram in treating post-stroke depression: a meta-analysis.


Instruction: What is the name of the randomized controlled trial of early sitting in ischemic stroke patients?

Output: SEVEL Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial of early sitting in ischemic stroke patients?. ### Response: SEVEL Study Group.


Instruction: What study was conducted by the SEVEL Study Group?

Output: Early Sitting in Ischemic Stroke Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study was conducted by the SEVEL Study Group?. ### Response: Early Sitting in Ischemic Stroke Patients.


Instruction: What is the name of the randomized controlled trial of SEVEL?

Output: SEVEL Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial of SEVEL?. ### Response: SEVEL Study Group.


Instruction: When did SEVEL take place?

Output: Early Sitting in Ischemic Stroke Patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did SEVEL take place?. ### Response: Early Sitting in Ischemic Stroke Patients.


Instruction: What is a proprioceptive or cognitive approach in stroke patients?

Output: Early versus delayed rehabilitation treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a proprioceptive or cognitive approach in stroke patients?. ### Response: Early versus delayed rehabilitation treatment.


Instruction: What does Eur J Phys Rehabil Med. 2016:52:81–89?

Output: cognitive approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Eur J Phys Rehabil Med. 2016:52:81–89?. ### Response: cognitive approach.


Instruction: What is the cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack?

Output: Cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack. Med Decis Making. 2007;27:161–177

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack?. ### Response: Cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack. Med Decis Making. 2007;27:161–177.


Instruction: What is a cost-effectiveness analysis for stroke management?

Output: Echocardiographic identification of cardiovascular sources of emboli

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cost-effectiveness analysis for stroke management?. ### Response: Echocardiographic identification of cardiovascular sources of emboli.


Instruction: What is the name of the study that identified cardiovascular sources of emboli to guide clinical management of stroke?

Output: Echocardiographic identification of cardiovascular sources of emboli to guide clinical management of stroke: a cost-effectiveness analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that identified cardiovascular sources of emboli to guide clinical management of stroke?. ### Response: Echocardiographic identification of cardiovascular sources of emboli to guide clinical management of stroke: a cost-effectiveness analysis.


Instruction: How many strokes were there in 2007?

Output: 27:161

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in 2007?. ### Response: 27:161.


Instruction: Med. 1997;127:775–787. doi: 10.7326/0003-4819-127-9-199711010-00001 491. Shariat A, Yaghoubi E, Farazdaghi M, Aghasadeghi K, Borhani Haghighi A. Comparison of medical treatments in cryptogenic stroke patients with patent foramen ovale: a randomized clinical trial?

Output: Ann Intern

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Med. 1997;127:775–787. doi: 10.7326/0003-4819-127-9-199711010-00001 491. Shariat A, Yaghoubi E, Farazdaghi M, Aghasadeghi K, Borhani Haghighi A. Comparison of medical treatments in cryptogenic stroke patients with patent foramen ovale: a randomized clinical trial?. ### Response: Ann Intern.


Instruction: What is the name of the PICSS Investigators?

Output: PFO in Cryptogenic Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PICSS Investigators?. ### Response: PFO in Cryptogenic Stroke Study.


Instruction: What is one of the effects of medical treatment in stroke patients with patent foramen ovale?

Output: Patent Foramen Ovale in Cryptogenic Stroke Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the effects of medical treatment in stroke patients with patent foramen ovale?. ### Response: Patent Foramen Ovale in Cryptogenic Stroke Study.


Instruction: What does Patent foramen ovale closure or medical therapy for secondary pre-vention of cryptogenic stroke do?

Output: an update meta-analysis of random-ized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Patent foramen ovale closure or medical therapy for secondary pre-vention of cryptogenic stroke do?. ### Response: an update meta-analysis of random-ized controlled trials.


Instruction: What is the doi: 10.1097/MD.0000000000011965?

Output: 494

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1097/MD.0000000000011965?. ### Response: 494.


Instruction: What is the name of the meta-analysis of randomized controlled trials?

Output: amen ovale closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of randomized controlled trials?. ### Response: amen ovale closure.


Instruction: What is another name for medical therapy for cryptogenic ischemic stroke?

Output: amen ovale closure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for medical therapy for cryptogenic ischemic stroke?. ### Response: amen ovale closure.


Instruction: What does Clin Res Cardiol 107:745-755 say about secondary prevention of cryptogenic stroke?

Output: Patent foramen ovale closure or medical therapy for secondary pre-vention of cryptogenic stroke: an update meta-analysis of random-ized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Clin Res Cardiol 107:745-755 say about secondary prevention of cryptogenic stroke?. ### Response: Patent foramen ovale closure or medical therapy for secondary pre-vention of cryptogenic stroke: an update meta-analysis of random-ized controlled trials.


Instruction: In patients with patent foramen ovale: a systematic review and meta-analysis?

Output: Secondary prevention of cryptogenic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with patent foramen ovale: a systematic review and meta-analysis?. ### Response: Secondary prevention of cryptogenic stroke.


Instruction: Intern Emerg Med. 2018;13:1287-1303. doi: 10.1007/s11739-018-1909-8.

Output: amen ovale closure or medical therapy for cryptogenic ischemic stroke: an updated meta-analysis of randomized controlled trials. Clin Res Cardiol. 2018;107:745–755. doi: 10.1007/s00392-018-1224-4 495. Fiorelli EM, Carandini T, Gagliardi D, Bozzano V , Bonzi M, Tobaldini E, Comi GP, Scarpini EA, Montano N, Solbiati M. Secondary prevention of cryptogenic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Intern Emerg Med. 2018;13:1287-1303. doi: 10.1007/s11739-018-1909-8.. ### Response: amen ovale closure or medical therapy for cryptogenic ischemic stroke: an updated meta-analysis of randomized controlled trials. Clin Res Cardiol. 2018;107:745–755. doi: 10.1007/s00392-018-1224-4 495. Fiorelli EM, Carandini T, Gagliardi D, Bozzano V , Bonzi M, Tobaldini E, Comi GP, Scarpini EA, Montano N, Solbiati M. Secondary prevention of cryptogenic stroke.


Instruction: What are the long-term results of cuspid aortic valve replacement?

Output: Two decades

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the long-term results of cuspid aortic valve replacement?. ### Response: Two decades.


Instruction: What is the name of the valve that should be replaced more frequently in patients with bicuspid valve disease?

Output: ascending aorta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the valve that should be replaced more frequently in patients with bicuspid valve disease?. ### Response: ascending aorta.


Instruction: What type of valve surgery is associated with a pro-active ascending aorta repair?

Output: Bicuspid aortic valve sur -gery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve surgery is associated with a pro-active ascending aorta repair?. ### Response: Bicuspid aortic valve sur -gery.


Instruction: What year did J Thorac Cardiovasc Surg publish 142:622-9, 9.9.e1–3?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Thorac Cardiovasc Surg publish 142:622-9, 9.9.e1–3?. ### Response: 2011.


Instruction: Beckerman Z, Kayatta MO, McPherson L, et al. found a bicuspid valve repair in the setting of severe what?

Output: aortic insufficiency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beckerman Z, Kayatta MO, McPherson L, et al. found a bicuspid valve repair in the setting of severe what?. ### Response: aortic insufficiency.


Instruction: J Vis Surg. 2018;4:101

Output: Bicuspid aortic valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Vis Surg. 2018;4:101. ### Response: Bicuspid aortic valve repair.


Instruction: What year did J Vis Surg. 2018:4:101?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did J Vis Surg. 2018:4:101?. ### Response: 2011.


Instruction: How long did David TE, Feindel CM, David C, et al. experince with aortic valve-sparing operations?

Output: A quarter of a century

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did David TE, Feindel CM, David C, et al. experince with aortic valve-sparing operations?. ### Response: A quarter of a century.


Instruction: When did Davies RR, Kaple RK, Mandapati D, and others have a natural history of ascending aneurysms?

Output: in the setting of an unreplaced bicuspid aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Davies RR, Kaple RK, Mandapati D, and others have a natural history of ascending aneurysms?. ### Response: in the setting of an unreplaced bicuspid aortic valve.


Instruction: What is a natural history of?

Output: ascending aortic aneurysms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a natural history of?. ### Response: ascending aortic aneurysms.


Instruction: What is the setting of an unreplaced bicuspid aortic valve?

Output: Natural history of ascending aortic aneurysms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the setting of an unreplaced bicuspid aortic valve?. ### Response: Natural history of ascending aortic aneurysms.


Instruction: When did Ergin MA, Spielvogel D, Apaydin A, et al. surgical treatment of the dilated ascending Aorta: when and how?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Ergin MA, Spielvogel D, Apaydin A, et al. surgical treatment of the dilated ascending Aorta: when and how?. ### Response: 11.


Instruction: Ann Thorac Surg. 1999;67:1834–9. 12. Svensson LG, Kim K-H, Lytle BW, et al. Relationship of aortic cross-sec-tional area to height ratio and the risk of dissection in patients with what type of valves?

Output: bicuspid aortic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ann Thorac Surg. 1999;67:1834–9. 12. Svensson LG, Kim K-H, Lytle BW, et al. Relationship of aortic cross-sec-tional area to height ratio and the risk of dissection in patients with what type of valves?. ### Response: bicuspid aortic valves.


Instruction: What type of valve is used to prevent progressive dilation of ascending aorta?

Output: aortic valve replacement in patients with bicuspid aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of valve is used to prevent progressive dilation of ascending aorta?. ### Response: aortic valve replacement in patients with bicuspid aortic valve.