Instruction: What does Xie CC, Mehta S, et al. report on?

Output: Differences in the management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Xie CC, Mehta S, et al. report on?. ### Response: Differences in the management.


Instruction: What is the main difference between management and management?

Output: gender

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the main difference between management and management?. ### Response: gender.


Instruction: What is the name of the multi-ethnic study of atherosclerosis?

Output: MESA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-ethnic study of atherosclerosis?. ### Response: MESA.


Instruction: What suggests the presence of major confounders of data interpretation?

Output: SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What suggests the presence of major confounders of data interpretation?. ### Response: SBP.


Instruction: What does not SBP suggest?

Output: the presence of major confounders of data interpretation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not SBP suggest?. ### Response: the presence of major confounders of data interpretation.


Instruction: How will the vast majority of hyperten-sive individuals experience problems related to lowering of DBP?

Output: will not experience problems related to lowering of DBP when standard antihypertensive medications are used

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How will the vast majority of hyperten-sive individuals experience problems related to lowering of DBP?. ### Response: will not experience problems related to lowering of DBP when standard antihypertensive medications are used.


Instruction: What does not experience problems related to lowering of DBP when standard antihypertensive medications are used?

Output: hyperten-sive individuals, including those with overt cardiac disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not experience problems related to lowering of DBP when standard antihypertensive medications are used?. ### Response: hyperten-sive individuals, including those with overt cardiac disease.


Instruction: Concerns that coronary perfusion is limited by an autoregulatory threshold have not yet been validated in humans with healthy or even diseased coronary arteries?

Output: no consensus exists on the min-imum safe level of DBP in these individuals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Concerns that coronary perfusion is limited by an autoregulatory threshold have not yet been validated in humans with healthy or even diseased coronary arteries?. ### Response: no consensus exists on the min-imum safe level of DBP in these individuals.


Instruction: No consensus exists on the min-imum safe level of what?

Output: DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No consensus exists on the min-imum safe level of what?. ### Response: DBP.


Instruction: What is the minimum safe level of DBP in humans?

Output: min-imum safe level of DBP in these individuals. Although an auto-regulatory threshold has not been defined in humans, with or without CAD, it is clear, mainly from ACCORD, that lower BP targets, down to levels <120/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the minimum safe level of DBP in humans?. ### Response: min-imum safe level of DBP in these individuals. Although an auto-regulatory threshold has not been defined in humans, with or without CAD, it is clear, mainly from ACCORD, that lower BP targets, down to levels <120/80 mm Hg.


Instruction: What has not been defined in humans, with or without CAD?

Output: auto-regulatory threshold

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been defined in humans, with or without CAD?. ### Response: auto-regulatory threshold.


Instruction: How do lower BP targets protect against stroke?

Output: down to levels <120/80 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do lower BP targets protect against stroke?. ### Response: down to levels <120/80 mm Hg.


Instruction: What does mm Hg do to protect against stroke?

Output: lower BP targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does mm Hg do to protect against stroke?. ### Response: lower BP targets.


Instruction: When was the aha journal published?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the aha journal published?. ### Response: May 3, 2023.


Instruction: What should all patients with suspected acute stroke receive on first arrival to a hospital before initiating any specific therapy to treat AIS?

Output: emergency brain imaging evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all patients with suspected acute stroke receive on first arrival to a hospital before initiating any specific therapy to treat AIS?. ### Response: emergency brain imaging evaluation.


Instruction: e356 Stroke December 20192.2. Head and Neck Imaging2.2.1. Initial Imaging COR LOE New, Revised, or Unchanged1.

Output: clinical presentation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: e356 Stroke December 20192.2. Head and Neck Imaging2.2.1. Initial Imaging COR LOE New, Revised, or Unchanged1.. ### Response: clinical presentation.


Instruction: What should be established so that brain imaging studies can be performed as quickly as possible in patients with AIS?

Output: Systems

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be established so that brain imaging studies can be performed as quickly as possible in patients with AIS?. ### Response: Systems.


Instruction: What is the benefit of IV alteplase time dependent?

Output: earlier treatment within the therapeutic window leading to bigger proportional benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of IV alteplase time dependent?. ### Response: earlier treatment within the therapeutic window leading to bigger proportional benefits.


Instruction: What is recommended as a study to exclude ICH?

Output: A brain imaging study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended as a study to exclude ICH?. ### Response: A brain imaging study.


Instruction: What is recommended as part of the initial evaluation of patients who are potentially eligible for these therapies?

Output: A brain imaging study to exclude ICH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended as part of the initial evaluation of patients who are potentially eligible for these therapies?. ### Response: A brain imaging study to exclude ICH.


Instruction: How many randomized trials did a pooled analysis of 5 compare with medical therapy alone?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomized trials did a pooled analysis of 5 compare with medical therapy alone?. ### Response: 5.


Instruction: How long were the majority of patients treated within?

Output: 6 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long were the majority of patients treated within?. ### Response: 6 hours.


Instruction: How did the odds of improved disability outcomes at 90 days decrease with longer time from symptom onset to arterial puncture?

Output: declined

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the odds of improved disability outcomes at 90 days decrease with longer time from symptom onset to arterial puncture?. ### Response: declined.


Instruction: The 6- to 16- and 6- to 24-hour time spans were what?

Output: treatment windows trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The 6- to 16- and 6- to 24-hour time spans were what?. ### Response: treatment windows trials.


Instruction: What did the 6- to 16- and 6- to 24-hour treatment windows trials use to identify a relatively uniform patient group?

Output: advanced imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 6- to 16- and 6- to 24-hour treatment windows trials use to identify a relatively uniform patient group?. ### Response: advanced imaging.


Instruction: The absence of detailed screening logs in these trials limits estimations of what?

Output: the true impact of time in this population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The absence of detailed screening logs in these trials limits estimations of what?. ### Response: the true impact of time in this population.


Instruction: What limits estimations of the true impact of time in this population?

Output: The absence of detailed screening logs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What limits estimations of the true impact of time in this population?. ### Response: The absence of detailed screening logs.


Instruction: To ensure that the highest proportion of eligible patients present in the 6- to 24-hour window have access to mechanical thrombectomy, evaluation and treatment should be as rapid as possible?

Output: absence of detailed screening logs in these trials limits estimations of the true impact of time in this population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To ensure that the highest proportion of eligible patients present in the 6- to 24-hour window have access to mechanical thrombectomy, evaluation and treatment should be as rapid as possible?. ### Response: absence of detailed screening logs in these trials limits estimations of the true impact of time in this population.


Instruction: What should be as rapid as possible?

Output: evaluation and treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be as rapid as possible?. ### Response: evaluation and treatment.


Instruction: What can help to reduce the time to treatment initiation?

Output: ED presentation to initial brain imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can help to reduce the time to treatment initiation?. ### Response: ED presentation to initial brain imaging.


Instruction: Studies have shown that median or mean door-to-imaging times of 20 minutes can be achieved in a variety of different hospital settings?

Output: 79

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Studies have shown that median or mean door-to-imaging times of 20 minutes can be achieved in a variety of different hospital settings?. ### Response: 79.


Instruction: What is effective to exclude ICH before IV alteplase administration?

Output: A brain imaging study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective to exclude ICH before IV alteplase administration?. ### Response: A brain imaging study.


Instruction: What is CTA with CTP or MR angiography with DW-MRI?

Output: MRA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CTA with CTP or MR angiography with DW-MRI?. ### Response: MRA.


Instruction: How can a diagnosis of ischemic stroke be made?

Output: emergency brain imaging evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can a diagnosis of ischemic stroke be made?. ### Response: emergency brain imaging evaluation.


Instruction: What can be detected in the majority of patients with careful attention?

Output: ischemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be detected in the majority of patients with careful attention?. ### Response: ischemic stroke.


Instruction: What is the NICE guideline on intrapar tum car e for women?

Output: 1.7.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NICE guideline on intrapar tum car e for women?. ### Response: 1.7.2.


Instruction: What is tum car e for women wit h hyper tension whet her tr eated?

Output: intrapar tum car e for women wit h hyper tension whet her tr eated or untr eated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tum car e for women wit h hyper tension whet her tr eated?. ### Response: intrapar tum car e for women wit h hyper tension whet her tr eated or untr eated.


Instruction: What is not just on the basis of blood pr essur e in labour?

Output: hyper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not just on the basis of blood pr essur e in labour?. ### Response: hyper tension.


Instruction: What is the NICE guideline on intrapar tum car e for women wit h existing medical conditions or obstetric complications and their babies?

Output: 1.7.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NICE guideline on intrapar tum car e for women wit h existing medical conditions or obstetric complications and their babies?. ### Response: 1.7.2.


Instruction: What is blood pr essur e 1.7.3 During labour?

Output: hourly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is blood pr essur e 1.7.3 During labour?. ### Response: hourly.


Instruction: During labour, measur e blood pr essur?

Output: • hourly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: During labour, measur e blood pr essur?. ### Response: • hourly.


Instruction: Every 15-30 minutes until blood pr sessur is less than 160/110 mmHg in what?

Output: w omen with severe hyper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Every 15-30 minutes until blood pr sessur is less than 160/110 mmHg in what?. ### Response: w omen with severe hyper tension.


Instruction: What do w omen with severe hyper tension need during labour?

Output: f or haemat ological and biochemical t ests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do w omen with severe hyper tension need during labour?. ### Response: f or haemat ological and biochemical t ests.


Instruction: What is continued use of ant enatal antih yper tensiv e treatment during labor?

Output: 1.7.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is continued use of ant enatal antih yper tensiv e treatment during labor?. ### Response: 1.7.4.


Instruction: During labour in w omen wit h hyper tension use t he same criteria as in what period?

Output: antenatal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: During labour in w omen wit h hyper tension use t he same criteria as in what period?. ### Response: antenatal.


Instruction: What is being considered if r egional analgesia is being considered?

Output: Determine t he need f or haemat ological and biochemical t ests during labour in w omen wit h hyper tension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is being considered if r egional analgesia is being considered?. ### Response: Determine t he need f or haemat ological and biochemical t ests during labour in w omen wit h hyper tension.


Instruction: What is the definition of epidur al analg esia?

Output: Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of epidur al analg esia?. ### Response: Care.


Instruction: Do not pr eload w omen who ha ve severe pre-eclampsio wit h intra venous fluids bef ore establishing lo w-dose epidural analgesia or combined spinal epidural analgesesia 1.7.6?

Output: Do not r outinely limit t he duration of t he second stage of labour in women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Do not pr eload w omen who ha ve severe pre-eclampsio wit h intra venous fluids bef ore establishing lo w-dose epidural analgesia or combined spinal epidural analgesesia 1.7.6?. ### Response: Do not r outinely limit t he duration of t he second stage of labour in women.


Instruction: What do not limit the duration of t he second stage of labour in women with controlled hyper tension?

Output: 1.7.7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do not limit the duration of t he second stage of labour in women with controlled hyper tension?. ### Response: 1.7.7.


Instruction: What is hyper tension in pregnancy: diagnosis and management?

Output: NG133

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hyper tension in pregnancy: diagnosis and management?. ### Response: NG133.


Instruction: What is NG133?

Output: Hyper tension in pr egnancy: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NG133?. ### Response: Hyper tension in pr egnancy: diagnosis and management.


Instruction: What is NICE 2023?

Output: Hyper tension in pr egnancy: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2023?. ### Response: Hyper tension in pr egnancy: diagnosis and management.


Instruction: When was the last updat?

Output: 17 April 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat?. ### Response: 17 April 2023.


Instruction: What is the name of the study that looked at long term surgical survival?

Output: Coronary Artery Surgery Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that looked at long term surgical survival?. ### Response: Coronary Artery Surgery Study.


Instruction: What year did the J Am Coll Cardiol issue 33:488–98.1171.

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the J Am Coll Cardiol issue 33:488–98.1171.. ### Response: 1999.


Instruction: What is a name for bilateral internal thoracic arteries?

Output: Thorac Cardiovasc Surg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a name for bilateral internal thoracic arteries?. ### Response: Thorac Cardiovasc Surg.


Instruction: What has not influenced the mortality dis-advantage in patients with diabetes mellitus?

Output: Improved survival aftercoronary artery bypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not influenced the mortality dis-advantage in patients with diabetes mellitus?. ### Response: Improved survival aftercoronary artery bypass grafting.


Instruction: What has improved survival after coronary artery bypass grafting?

Output: Surgical revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has improved survival after coronary artery bypass grafting?. ### Response: Surgical revascularization.


Instruction: When was the J Thorac Cardiovasc Surg 138:1115-22.1172 published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg 138:1115-22.1172 published?. ### Response: 2009.


Instruction: What is the effect of risk-adjusteddiabetes on mortality and morbidity after coronary artery bypasssurgery?

Output: dramaticincreases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of risk-adjusteddiabetes on mortality and morbidity after coronary artery bypasssurgery?. ### Response: dramaticincreases.


Instruction: What is Singh SK, Desai ND, Petroff SD, et al.?

Output: The impact of diabetic status oncoronary artery bypass graft patency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Singh SK, Desai ND, Petroff SD, et al.?. ### Response: The impact of diabetic status oncoronary artery bypass graft patency.


Instruction: What is associated with improved long-term outcomes compared with percu-taneous stenting in most subgroups of patients with multivesselcoronary artery disease?

Output: Surgical revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with improved long-term outcomes compared with percu-taneous stenting in most subgroups of patients with multivesselcoronary artery disease?. ### Response: Surgical revascularization.


Instruction: What did Registry.Circulation. 2007:116:I226–31.1175.

Output: Intermountain Heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Registry.Circulation. 2007:116:I226–31.1175.. ### Response: Intermountain Heart.


Instruction: What was the design of the Future REvas-cularization Evaluation in patients with Diabetes mellitus?

Output: Optimalmanagement of Multivessel disease (FREEDOM) trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the design of the Future REvas-cularization Evaluation in patients with Diabetes mellitus?. ### Response: Optimalmanagement of Multivessel disease (FREEDOM) trial.


Instruction: What is the name of the Optimalmanagement of Multivessel disease trial?

Output: FREEDOM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Optimalmanagement of Multivessel disease trial?. ### Response: FREEDOM.


Instruction: What is the name of the randomized trial of different treatment strategies in type 2 diabetes mellitus with stableischemic heart disease?

Output: The Bypass AngioplastyRevascularization Investigation 2 Diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of different treatment strategies in type 2 diabetes mellitus with stableischemic heart disease?. ### Response: The Bypass AngioplastyRevascularization Investigation 2 Diabetes.


Instruction: What was the impact of treatment strategy on cardiac mor-tality and myocardial infarction?

Output: dramaticincreases in mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the impact of treatment strategy on cardiac mor-tality and myocardial infarction?. ### Response: dramaticincreases in mortality.


Instruction: When was Circulation. 2009;120:2529–40.1177?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation. 2009;120:2529–40.1177?. ### Response: 2009.


Instruction: What is predictive of adverse events after coronaryartery bypass surgery?

Output: Elevated preoperativehemoglobin A1c level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is predictive of adverse events after coronaryartery bypass surgery?. ### Response: Elevated preoperativehemoglobin A1c level.


Instruction: What predicts mor-tality after CABG?

Output: Hyperglycemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts mor-tality after CABG?. ### Response: Hyperglycemia.


Instruction: What type of surgery is used to treat diabetes?

Output: coronary artery bypasssurgery. Ann Thorac Surg. 2005;79:1570–6.1173. Singh SK, Desai ND, Petroff SD, et al. The impact of diabetic status oncoronary artery bypass graft patency: insights from the radial arterypatency study. Circulation. 2008;118:S222–5.1174. Bair TL, Muhlestein JB, May HT, et al. Surgical revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery is used to treat diabetes?. ### Response: coronary artery bypasssurgery. Ann Thorac Surg. 2005;79:1570–6.1173. Singh SK, Desai ND, Petroff SD, et al. The impact of diabetic status oncoronary artery bypass graft patency: insights from the radial arterypatency study. Circulation. 2008;118:S222–5.1174. Bair TL, Muhlestein JB, May HT, et al. Surgical revascularization.


Instruction: What is the cause of sudden death in young competitive athletes?

Output: congenitalcoronary artery anomalies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of sudden death in young competitive athletes?. ### Response: congenitalcoronary artery anomalies.


Instruction: Where do anomalous coronary arteries originate?

Output: wrong aortic sinus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where do anomalous coronary arteries originate?. ### Response: wrong aortic sinus.


Instruction: What type of coronary arteries are between the aorta and pulmonary trunk?

Output: Anomalous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of coronary arteries are between the aorta and pulmonary trunk?. ### Response: Anomalous.


Instruction: What are the clinical indications for coronaryartery bypass?

Output: Anomalous coronaryarteries coursing between the aorta and pulmonary trunk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinical indications for coronaryartery bypass?. ### Response: Anomalous coronaryarteries coursing between the aorta and pulmonary trunk.


Instruction: When did Eur Heart J. 2012 issue 12:832–4.1181?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 2012 issue 12:832–4.1181?. ### Response: 1991.


Instruction: How long did surgery last?

Output: 79:1570–6.1173

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did surgery last?. ### Response: 79:1570–6.1173.


Instruction: Where do arteries originate from?

Output: opposite coronary cusp

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where do arteries originate from?. ### Response: opposite coronary cusp.


Instruction: Circulation. 2011;123:154–62.1182.

Output: surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2011;123:154–62.1182.. ### Response: surgery.


Instruction: Frommelt PC, Sheridan DC, Berger S, et al. Ten-year experience with what?

Output: coronary artery bypass

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Frommelt PC, Sheridan DC, Berger S, et al. Ten-year experience with what?. ### Response: coronary artery bypass.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Circulation. 2021;143:e72–e227

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Circulation. 2021;143:e72–e227.


Instruction: What are the recommendations summarized in in Online Data Supplement 32?

Output: Referenced studies that support the recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations summarized in in Online Data Supplement 32?. ### Response: Referenced studies that support the recommendations.


Instruction: What is recommended in patients with severe TR (Stages C and D) undergoing left-sided valve surgery?

Output: tricuspid valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with severe TR (Stages C and D) undergoing left-sided valve surgery?. ### Response: tricuspid valve surgery.


Instruction: What is tricuspid valve surgery recommended in?

Output: absence of severe pulmonary hypertension or severe RV systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tricuspid valve surgery recommended in?. ### Response: absence of severe pulmonary hypertension or severe RV systolic dysfunction.


Instruction: In patients with progressive TR, what can be beneficial in the context of either progressive TR or progressive TR?

Output: tricuspid valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with progressive TR, what can be beneficial in the context of either progressive TR or progressive TR?. ### Response: tricuspid valve surgery.


Instruction: What is tricuspid annulus end diastolic diameter >4.0 cm?

Output: tricuspid annular dilation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tricuspid annulus end diastolic diameter >4.0 cm?. ### Response: tricuspid annular dilation.


Instruction: In patients with signs and symptoms of right-sided HF and severe primary TR, what can be beneficial?

Output: isolated tricuspid valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with signs and symptoms of right-sided HF and severe primary TR, what can be beneficial?. ### Response: isolated tricuspid valve surgery.


Instruction: What can be beneficial for patients with right-sided HF and severe primary TR?

Output: isolated tricuspid valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial for patients with right-sided HF and severe primary TR?. ### Response: isolated tricuspid valve surgery.


Instruction: What can reduce symptoms and recurrent hospitalizations?

Output: valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can reduce symptoms and recurrent hospitalizations?. ### Response: valve surgery.


Instruction: What is annular dilation in the absence of pulmonary hypertension or left-sided disease?

Output: tricuspid annulus end diastolic diameter >4.0 cm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is annular dilation in the absence of pulmonary hypertension or left-sided disease?. ### Response: tricuspid annulus end diastolic diameter >4.0 cm.


Instruction: What can be beneficial to reduce symptoms and recurrent hospitalizations?

Output: valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial to reduce symptoms and recurrent hospitalizations?. ### Response: valve surgery.


Instruction: What may be considered in patients with signs and symptoms of right-sided HF and severe TR (Stage D) who have undergone previous left-sided valve surgery?

Output: isolated tricuspid valve surgery can be beneficial to reduce symptoms and recurrent hospitalizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered in patients with signs and symptoms of right-sided HF and severe TR (Stage D) who have undergone previous left-sided valve surgery?. ### Response: isolated tricuspid valve surgery can be beneficial to reduce symptoms and recurrent hospitalizations.


Instruction: What may be considered in the absence of severe pulmonary hypertension or severe RV systolic dysfunction?

Output: reoperation with isolated tricuspid valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered in the absence of severe pulmonary hypertension or severe RV systolic dysfunction?. ### Response: reoperation with isolated tricuspid valve surgery.


Instruction: Treatment of secondary TR is targeted at what?

Output: pulmonary hypertension or myocardial disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Treatment of secondary TR is targeted at what?. ### Response: pulmonary hypertension or myocardial disease.


Instruction: What is performed for selected patients with TR at the time of surgery?

Output: Surgical treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed for selected patients with TR at the time of surgery?. ### Response: Surgical treatment.


Instruction: What should be considered for selected patients with TR at the time of surgery for left-sided valve lesions?

Output: Surgical treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered for selected patients with TR at the time of surgery for left-sided valve lesions?. ### Response: Surgical treatment.


Instruction: To treat severe TR (Stages C and D) and to prevent later development of severe TR in patients with progressive TR?

Output: Surgical treatment is performed for selected patients with TR at the time of surgery for left-sided valve lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To treat severe TR (Stages C and D) and to prevent later development of severe TR in patients with progressive TR?. ### Response: Surgical treatment is performed for selected patients with TR at the time of surgery for left-sided valve lesions.


Instruction: What was considered for selected patients with isolated TR?

Output: Surgical intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered for selected patients with isolated TR?. ### Response: Surgical intervention.


Instruction: What was the high reported operative mortality rate for severe isolated TR (up to 8% to 20%)?

Output: Intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the high reported operative mortality rate for severe isolated TR (up to 8% to 20%)?. ### Response: Intervention.


Instruction: What percentage of interventions were performed after end-organ damage?

Output: most

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of interventions were performed after end-organ damage?. ### Response: most.


Instruction: What are the outcomes of patients with severe primary TR poor with?

Output: medical management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes of patients with severe primary TR poor with?. ### Response: medical management.


Instruction: There is renewed interest in earlier surgery for patients with se-vere isolated TR before the onset of severe RV dysfunc-tion or what?

Output: end-organ damage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is renewed interest in earlier surgery for patients with se-vere isolated TR before the onset of severe RV dysfunc-tion or what?. ### Response: end-organ damage.


Instruction: What is the term for severe RV dysfunc-tion?

Output: systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for severe RV dysfunc-tion?. ### Response: systolic dysfunction.


Instruction: Why is this interest attributable to an increasing number of patients?

Output: pre-

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is this interest attributable to an increasing number of patients?. ### Response: pre-.


Instruction: What is the ungraded consensus-based statement?

Output: Evidence-Based Medicine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ungraded consensus-based statement?. ### Response: Evidence-Based Medicine.


Instruction: What do we suggest for pregnant women?

Output: avoiding the useof NOACs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest for pregnant women?. ### Response: avoiding the useof NOACs.


Instruction: What antagonists are used instead of switching to LMWH while attempting pregnancy?

Output: vitamin K

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What antagonists are used instead of switching to LMWH while attempting pregnancy?. ### Response: vitamin K.


Instruction: For lactating women using warfarin, acenocoumarol or UFH who wish to breast-feed, we suggest continuing the use of what?

Output: warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For lactating women using warfarin, acenocoumarol or UFH who wish to breast-feed, we suggest continuing the use of what?. ### Response: warfarin.


Instruction: LMWH replaced by VKA until what week?

Output: 36th

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: LMWH replaced by VKA until what week?. ### Response: 36th.


Instruction: VKA replaced by what from 36th week to 24 hbefore delivery or cesarean section?

Output: LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: VKA replaced by what from 36th week to 24 hbefore delivery or cesarean section?. ### Response: LMWH.


Instruction: What is shown during lactation?

Output: VKA or LMWH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shown during lactation?. ### Response: VKA or LMWH.


Instruction: What does LMWH 14low-molecular-weight heparin?

Output: ¼

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LMWH 14low-molecular-weight heparin?. ### Response: ¼.


Instruction: What was the smoking rate in the United States in 1964?

Output: 45%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the smoking rate in the United States in 1964?. ### Response: 45%..


Instruction: What is tobacco use a leading modifiable cause of death in the US?

Output: cigarette smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tobacco use a leading modifiable cause of death in the US?. ### Response: cigarette smoking.


Instruction: What is the modifiable cause of death in the United States?

Output: tobacco use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the modifiable cause of death in the United States?. ### Response: tobacco use.


Instruction: What percentage of adult men and 16.7% of adult women still engage in cigarette smoking?

Output: 21.3%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of adult men and 16.7% of adult women still engage in cigarette smoking?. ### Response: 21.3%.


Instruction: In patients who have had CABG, smoking can adversely affect both short- and long-term clinical outcomes?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients who have had CABG, smoking can adversely affect both short- and long-term clinical outcomes?. ### Response: 1.


Instruction: Early after surgery, smokers have an increased rate of what?

Output: atelectasis and pneumonia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Early after surgery, smokers have an increased rate of what?. ### Response: atelectasis and pneumonia.


Instruction: In addition to atelectasis and pneumonia, what type of surgery does smokers have an increased rate of?

Output: cardiac

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to atelectasis and pneumonia, what type of surgery does smokers have an increased rate of?. ### Response: cardiac.


Instruction: Along with mechanical ventilation and intensive care support, what is a requirement for smokers in surgery?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Along with mechanical ventilation and intensive care support, what is a requirement for smokers in surgery?. ### Response: CABG.


Instruction: What is smoking associ-ated with in adults who undergo cardiac surgery in addition to an increased risk of pulmonary complications?

Output: deep sternal wound infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is smoking associ-ated with in adults who undergo cardiac surgery in addition to an increased risk of pulmonary complications?. ### Response: deep sternal wound infections.


Instruction: What are wound infections in adults who undergo cardiac surgery?

Output: deep sternal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are wound infections in adults who undergo cardiac surgery?. ### Response: deep sternal.


Instruction: Smokers have a higher prevalence of what type of ischemia?

Output: myocardial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Smokers have a higher prevalence of what type of ischemia?. ### Response: myocardial.


Instruction: What is smoking associated with?

Output: an increased risk of deep sternal wound infections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is smoking associated with?. ### Response: an increased risk of deep sternal wound infections.


Instruction: What is not significantly different in smokers compared with nonsmokers?

Output: early mortality rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not significantly different in smokers compared with nonsmokers?. ### Response: early mortality rates.


Instruction: What has been observed in long-term mortality rates?

Output: sig-nificant differences

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been observed in long-term mortality rates?. ### Response: sig-nificant differences.


Instruction: How long did self-reported smoking cessation after CABG be associated with?

Output: 3 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did self-reported smoking cessation after CABG be associated with?. ### Response: 3 years.


Instruction: What was associated with a life expectancy gain of 3 years after CABG?

Output: self-reported smoking cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a life expectancy gain of 3 years after CABG?. ### Response: self-reported smoking cessation.


Instruction: What had a greater effect on reducing the risk of mortality than any other intervention or treatment?

Output: smoking cessation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What had a greater effect on reducing the risk of mortality than any other intervention or treatment?. ### Response: smoking cessation.


Instruction: What may be a particularly effective time to use smoking cessation strategies?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be a particularly effective time to use smoking cessation strategies?. ### Response: CABG.


Instruction: What are smokers undergoing CABG subject to?

Output: hospitalized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are smokers undergoing CABG subject to?. ### Response: hospitalized.


Instruction: What may the conditions precipitating the need for CABG and the surgery itself reinforce?

Output: the smoker’s perceived vulnerability to the harms of tobacco use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may the conditions precipitating the need for CABG and the surgery itself reinforce?. ### Response: the smoker’s perceived vulnerability to the harms of tobacco use.


Instruction: What may motivate the patient to engage in an attempt at smoking cessation?

Output: The conditions precipitating the need for CABG and the surgery itself may also reinforce the smoker’s perceived vulnerability to the harms of tobacco use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may motivate the patient to engage in an attempt at smoking cessation?. ### Response: The conditions precipitating the need for CABG and the surgery itself may also reinforce the smoker’s perceived vulnerability to the harms of tobacco use.


Instruction: In a Scandinavian cohort of patients undergoing cardiac surgery, how much of the patients were smokers?

Output: one half

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a Scandinavian cohort of patients undergoing cardiac surgery, how much of the patients were smokers?. ### Response: one half.


Instruction: What percentage of current smokers gave up smoking after surgery?

Output: one half

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of current smokers gave up smoking after surgery?. ### Response: one half.


Instruction: What was most likely to occur during the first 6 postoperative months?

Output: changes in smoking behavior

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was most likely to occur during the first 6 postoperative months?. ### Response: changes in smoking behavior.


Instruction: When can CABG serve as a teachable moment?

Output: smoking ces-sation strategies may be highly effective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When can CABG serve as a teachable moment?. ### Response: smoking ces-sation strategies may be highly effective.


Instruction: What is a teachable moment during which smoking cessation strategies may be highly effective?

Output: CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a teachable moment during which smoking cessation strategies may be highly effective?. ### Response: CABG.


Instruction: What should begin with a full assessment of tobacco use and exposure?

Output: Smoking cessation strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should begin with a full assessment of tobacco use and exposure?. ### Response: Smoking cessation strategies.


Instruction: A cli-nician should determine the duration of what?

Output: smoking

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A cli-nician should determine the duration of what?. ### Response: smoking.


Instruction: What should every smoker be asked if he or she is interested in quitting smoking?

Output: all clinical encounters

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should every smoker be asked if he or she is interested in quitting smoking?. ### Response: all clinical encounters.


Instruction: How long does it take for a smoker to have their first morning cigarette?

Output: 299

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a smoker to have their first morning cigarette?. ### Response: 299.


Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e107 S12.4.2-8?

Output: Whelton et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e107 S12.4.2-8?. ### Response: Whelton et al.


Instruction: What is a role of home blood pressure monitoring in overcoming therapeutic inertia?

Output: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a role of home blood pressure monitoring in overcoming therapeutic inertia?. ### Response: a systematic review and meta-analysis.


Instruction: What is a meta-analysis?

Output: Role of home blood pres-sure monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis?. ### Response: Role of home blood pres-sure monitoring.


Instruction: What is an effective approach to high blood pressure control: a science advisory from the American Heart Association?

Output: AHA/ACCF secondary prevention and risk reduction therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an effective approach to high blood pressure control: a science advisory from the American Heart Association?. ### Response: AHA/ACCF secondary prevention and risk reduction therapy.


Instruction: What is the acronym for Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies?

Output: Hypertension Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies?. ### Response: Hypertension Care.


Instruction: Where is the Center for Medicare and Medicaid Services located?

Output: Rockville, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Center for Medicare and Medicaid Services located?. ### Response: Rockville, MD.


Instruction: What is the acronym for Million Hearts: Cardiovascular Disease Risk Reduction Model?

Output: Million-Hearts-CVDRRM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Million Hearts: Cardiovascular Disease Risk Reduction Model?. ### Response: Million-Hearts-CVDRRM.


Instruction: When did the Center for Medicare and Medicaid Services release the Million Hearts: CVDRRM?

Output: October 30, 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Center for Medicare and Medicaid Services release the Million Hearts: CVDRRM?. ### Response: October 30, 2017.


Instruction: What are financial incentives and physician commitment to?

Output: guideline-recommended hypertension management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are financial incentives and physician commitment to?. ### Response: guideline-recommended hypertension management.


Instruction: What is a guideline-recommended hypertension management?

Output: Financial incentives and physician commitment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a guideline-recommended hypertension management?. ### Response: Financial incentives and physician commitment.


Instruction: What is the impact of pay for perforation on hypertension care?

Output: control of blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of pay for perforation on hypertension care?. ### Response: control of blood pressure.


Instruction: What is the impact of pay for perfor -mance on the control of blood pressure in people with chronic kidney disease stage 3-5?

Output: Karunaratne K, Stevens P, Irving J, et al. The impact of pay for perfor -mance on the control of blood pressure in people with chronic kidney disease stage 3–5. Nephrol Dial Transplant. 2013;28:2107–16. S12.5-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of pay for perfor -mance on the control of blood pressure in people with chronic kidney disease stage 3-5?. ### Response: Karunaratne K, Stevens P, Irving J, et al. The impact of pay for perfor -mance on the control of blood pressure in people with chronic kidney disease stage 3–5. Nephrol Dial Transplant. 2013;28:2107–16. S12.5-4.


Instruction: What does Irving J, Perel P, and Maimaris W do?

Output: control of blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Irving J, Perel P, and Maimaris W do?. ### Response: control of blood pressure.


Instruction: What is the name of the systematic literature review of health systems on hypertension awareness, treatment, and control?

Output: PLoS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic literature review of health systems on hypertension awareness, treatment, and control?. ### Response: PLoS.


Instruction: What year was Million Hearts: Cardiovascular Disease Risk Reduction Model released?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was Million Hearts: Cardiovascular Disease Risk Reduction Model released?. ### Response: 2016.


Instruction: How long did it take Kaiser Permanente Northern California to improve hypertension control?

Output: 13 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take Kaiser Permanente Northern California to improve hypertension control?. ### Response: 13 years.


Instruction: What is the name of the organization that improved control of hypertension from 44% to 90% in 13 years?

Output: Kaiser Permanente

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that improved control of hypertension from 44% to 90% in 13 years?. ### Response: Kaiser Permanente.


Instruction: What does AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease do?

Output: a guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease do?. ### Response: a guideline.


Instruction: What is a 2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of?

Output: the guideline for the diagnosis and management of patients with stable ischemic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of?. ### Response: the guideline for the diagnosis and management of patients with stable ischemic heart disease.


Instruction: What is the focus of the 2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of?

Output: the guideline for the diagnosis and management of patients with stable ischemic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the 2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of?. ### Response: the guideline for the diagnosis and management of patients with stable ischemic heart disease.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: 2011 update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: 2011 update.


Instruction: What is anatomic and prognostic significance of new T-wave inversion in unstable angina?

Output: Long-term prognosis of patients with clinical unstable angina pectoris without elevation of creatine kinase but with elevation of cardiac troponin i levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is anatomic and prognostic significance of new T-wave inversion in unstable angina?. ### Response: Long-term prognosis of patients with clinical unstable angina pectoris without elevation of creatine kinase but with elevation of cardiac troponin i levels.


Instruction: What year did Am J Cardiol. 1983:52:14–8?

Output: 1983

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Am J Cardiol. 1983:52:14–8?. ### Response: 1983.


Instruction: What is the name of the international randomized trial of emergency PTCA/CABG-trial design?

Output: The SHOCK Trial Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the international randomized trial of emergency PTCA/CABG-trial design?. ### Response: The SHOCK Trial Study Group.


Instruction: When did the SHOCK Trial Study Group publish?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the SHOCK Trial Study Group publish?. ### Response: 1999.


Instruction: What was Holmes DR Jr., Berger PB, Hochman JS, et al. doing?

Output: Cardiogenic shock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was Holmes DR Jr., Berger PB, Hochman JS, et al. doing?. ### Response: Cardiogenic shock.


Instruction: What is the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays called?

Output: frequency of acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays called?. ### Response: frequency of acute myocardial infarction.


Instruction: What are the two types of ischemic syndromes with and without ST-segment elevation?

Output: acute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two types of ischemic syndromes with and without ST-segment elevation?. ### Response: acute.


Instruction: What is the global registry of acute coronary events?

Output: GRACE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the global registry of acute coronary events?. ### Response: GRACE.


Instruction: What are the lessons from the Global Registry of Acute Coronary Events?

Output: The diagnostic and prognostic impact of the redefinition of acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the lessons from the Global Registry of Acute Coronary Events?. ### Response: The diagnostic and prognostic impact of the redefinition of acute myocardial infarction.


Instruction: What is the clinical impact of the troponin 99th percentile cut-off and clinical utility of myoglobin measurement in the early management of chest pain patients admitted to the Emergency Cardiology Department?

Output: 154

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the clinical impact of the troponin 99th percentile cut-off and clinical utility of myoglobin measurement in the early management of chest pain patients admitted to the Emergency Cardiology Department?. ### Response: 154.


Instruction: What is Takakuwa KM, Ou FS, Peterson ED, et al.?

Output: 155

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Takakuwa KM, Ou FS, Peterson ED, et al.?. ### Response: 155.


Instruction: What is the use pattern of cardiac bedside markers employing point-of-care testing for troponin in non-ST-segment elevation acute coronary syndrome: results from CRUSADE?

Output: 155

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use pattern of cardiac bedside markers employing point-of-care testing for troponin in non-ST-segment elevation acute coronary syndrome: results from CRUSADE?. ### Response: 155.


Instruction: What is the requirement for the 6-hour interval between specimens in the American Heart Association Classification of Myocardial Infarction in Epidemiology?

Output: Assessing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the requirement for the 6-hour interval between specimens in the American Heart Association Classification of Myocardial Infarction in Epidemiology?. ### Response: Assessing.


Instruction: What is the American Heart Association Classification of Myocardial Infarction in Epidemiology and Clinical Research Studies?

Output: 6-hour interval between specimens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the American Heart Association Classification of Myocardial Infarction in Epidemiology and Clinical Research Studies?. ### Response: 6-hour interval between specimens.


Instruction: When was Clin Chem published?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Clin Chem published?. ### Response: 2006.


Instruction: What is an undertreated but high-risk patient group?

Output: Troponin-positive, MB-negative patients with non-ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an undertreated but high-risk patient group?. ### Response: Troponin-positive, MB-negative patients with non-ST-elevation myocardial infarction.


Instruction: What is the acronym for the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network-Get With The Guidelines?

Output: NCDR ACTION-GWTG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network-Get With The Guidelines?. ### Response: NCDR ACTION-GWTG.


Instruction: What does NCDR ACTION-GWTG stand for?

Output: Treatment and Intervention Outcomes Network-Get With The Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NCDR ACTION-GWTG stand for?. ### Response: Treatment and Intervention Outcomes Network-Get With The Guidelines.


Instruction: When did Aviles RJ, Wright RS, Aviles JM, et al. publish?

Output: 159

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Aviles RJ, Wright RS, Aviles JM, et al. publish?. ### Response: 159.


Instruction: What does pectoris without elevation of creatine kinase but with elevation of cardiac troponin i levels?

Output: Long-term prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does pectoris without elevation of creatine kinase but with elevation of cardiac troponin i levels?. ### Response: Long-term prognosis.


Instruction: What is the diagnostic value of serial measurement of cardiac markers in patients with chest pain?

Output: limited value of adding myoglobin to troponin I for exclusion of myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diagnostic value of serial measurement of cardiac markers in patients with chest pain?. ### Response: limited value of adding myoglobin to troponin I for exclusion of myocardial infarction.


Instruction: What is the limited value of adding myoglobin to troponin I for exclusion of myocardial infarction?

Output: Diagnostic value of serial measurement of cardiac markers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the limited value of adding myoglobin to troponin I for exclusion of myocardial infarction?. ### Response: Diagnostic value of serial measurement of cardiac markers.


Instruction: Am Heart J. 2004;148:574–81. 16.1. What is Creatine kinase-MB?

Output: elevation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Am Heart J. 2004;148:574–81. 16.1. What is Creatine kinase-MB?. ### Response: elevation.


Instruction: What is the sensitivity of CT in the first 3 days after aSAH?

Output: close to 100%),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sensitivity of CT in the first 3 days after aSAH?. ### Response: close to 100%),.


Instruction: What decreases moderately during the next few days?

Output: The sensitivity of CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What decreases moderately during the next few days?. ### Response: The sensitivity of CT.


Instruction: After how many days does the rate of negative CT increase sharply?

Output: 5 to 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After how many days does the rate of negative CT increase sharply?. ### Response: 5 to 7.


Instruction: What is often required to show xanthochromia?

Output: lumbar puncture

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is often required to show xanthochromia?. ### Response: lumbar puncture.


Instruction: Advances in magnetic resonanceimaging of the brain can often allow thediagnosis of what?

Output: aSAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Advances in magnetic resonanceimaging of the brain can often allow thediagnosis of what?. ### Response: aSAH.


Instruction: What is aSAH to be made when a head CT scan is negative?

Output: diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aSAH to be made when a head CT scan is negative?. ### Response: diagnosis.


Instruction: What is the role of magneticresonance imaging in perimesencephalic asAH controversial?

Output: controver-sial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of magneticresonance imaging in perimesencephalic asAH controversial?. ### Response: controver-sial.


Instruction: What is a limitation of routine?

Output: magnetic resonance angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a limitation of routine?. ### Response: magnetic resonance angiography.


Instruction: When was Stroke June 2012Downloaded by on April 28, 2023

Output: 1718

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Stroke June 2012Downloaded by on April 28, 2023. ### Response: 1718.


Instruction: What is the acronym for the Committee on the Man-agement of Patients With Unstable Angina?

Output: American College of Cardiology/American Heart Asso-ciation task force on practice guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Committee on the Man-agement of Patients With Unstable Angina?. ### Response: American College of Cardiology/American Heart Asso-ciation task force on practice guidelines.


Instruction: When was the ACC/AHA 2002guideline update?

Output: 6:248–52.1108

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the ACC/AHA 2002guideline update?. ### Response: 6:248–52.1108.


Instruction: On the Man-agement of Patients With Unstable Angina). Circulation. 2002;106:1893–900.1109. Ferraris VA, Ferraris SP, Saha SP, et al. Perioperative blood trans-fusion and blood conservation in cardiac surgery: the Society ofThoracic Surgeons and The Society of Cardiovascular Anesthesiol-ogists clinical practice guideline.

Output: Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On the Man-agement of Patients With Unstable Angina). Circulation. 2002;106:1893–900.1109. Ferraris VA, Ferraris SP, Saha SP, et al. Perioperative blood trans-fusion and blood conservation in cardiac surgery: the Society ofThoracic Surgeons and The Society of Cardiovascular Anesthesiol-ogists clinical practice guideline.. ### Response: Committee.


Instruction: Ann Thorac Surg. 2007;83 5 Suppl:S27–S86.1110.

Output: Perioperative blood trans-fusion and blood conservation in cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ann Thorac Surg. 2007;83 5 Suppl:S27–S86.1110.. ### Response: Perioperative blood trans-fusion and blood conservation in cardiac surgery.


Instruction: What is the name of the Society of ThoracicSurgeons practice guideline series?

Output: aspirin and other antiplatelet agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Society of ThoracicSurgeons practice guideline series?. ### Response: aspirin and other antiplatelet agents.


Instruction: What is aprotinin andlysine-derived antifibrinolytic drugs used for in operative coronary revascularization?

Output: cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aprotinin andlysine-derived antifibrinolytic drugs used for in operative coronary revascularization?. ### Response: cardiac surgery.


Instruction: What is aprotinin andlysine-derived antifibrinolytic drugs used for in cardiac surgery?

Output: The safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aprotinin andlysine-derived antifibrinolytic drugs used for in cardiac surgery?. ### Response: The safety.


Instruction: What is the name of the recombinant human eryth-ropoietin?

Output: epoetin beta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the recombinant human eryth-ropoietin?. ### Response: epoetin beta.


Instruction: What is recombinant human erythropoietin?

Output: epoetin beta

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recombinant human erythropoietin?. ### Response: epoetin beta.


Instruction: What is the name of the drug used to treat coronary bypass patients?

Output: epoetin alfa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat coronary bypass patients?. ### Response: epoetin alfa.


Instruction: In what year did Minerva Cardioangiol. 2000 issue 48?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Minerva Cardioangiol. 2000 issue 48?. ### Response: 2000.


Instruction: What is recombinanthuman erythropoietin?

Output: epoetin-alpha

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recombinanthuman erythropoietin?. ### Response: epoetin-alpha.


Instruction: What is the name of the drug used in patients treated with epoetine-alpha?

Output: recombinanthuman erythropoietin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used in patients treated with epoetine-alpha?. ### Response: recombinanthuman erythropoietin.


Instruction: When was the Minerva Cardioangiol.48:341–7.1115 published?

Output: 2000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Minerva Cardioangiol.48:341–7.1115 published?. ### Response: 2000.


Instruction: What is used before coronaryartery bypass surgery?

Output: Subcutaneous epoetin alfa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used before coronaryartery bypass surgery?. ### Response: Subcutaneous epoetin alfa.


Instruction: What is the name of the double-blind, multicenter trial in Japan?

Output: Subcutaneous administrationof recombinant human erythropoietin before cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the double-blind, multicenter trial in Japan?. ### Response: Subcutaneous administrationof recombinant human erythropoietin before cardiac surgery.


Instruction: What is used in autologousblood donation programs for patients scheduled for elective cardiacsurgery?

Output: epoetin alfa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used in autologousblood donation programs for patients scheduled for elective cardiacsurgery?. ### Response: epoetin alfa.


Instruction: When did Semin Hematol issue 33:75–6.1119?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Semin Hematol issue 33:75–6.1119?. ### Response: 1996.


Instruction: What is the name of the drug used in subcutaneous use of erythro-poietin?

Output: epoetin-alpha

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used in subcutaneous use of erythro-poietin?. ### Response: epoetin-alpha.


Instruction: What is the name of the drug used in autologous blood donation in anemic patients?

Output: epoetin alfa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used in autologous blood donation in anemic patients?. ### Response: epoetin alfa.


Instruction: What is epoetin alfa used for before elective coronary artery bypass graft surgery?

Output: autologousblood donation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is epoetin alfa used for before elective coronary artery bypass graft surgery?. ### Response: autologousblood donation.


Instruction: What is the 2014 AHA/ACC NSTE-ACS Guideline e3937.14?

Output: Amsterdam et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2014 AHA/ACC NSTE-ACS Guideline e3937.14?. ### Response: Amsterdam et al.


Instruction: What is associated with conditions such as dyslipidemia, diabetes mellitus, hypertension, arrhythmias, and HF that adversely affect ACS outcomes?

Output: ObesityObesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with conditions such as dyslipidemia, diabetes mellitus, hypertension, arrhythmias, and HF that adversely affect ACS outcomes?. ### Response: ObesityObesity.


Instruction: In the MADIT (Multicenter Automatic Defibrillator Implantation)-II trial, what was an inverse relation between body mass index and both all-cause mortality?

Output: sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the MADIT (Multicenter Automatic Defibrillator Implantation)-II trial, what was an inverse relation between body mass index and both all-cause mortality?. ### Response: sudden cardiac death.


Instruction: What is the inverse relation between body mass index and all-cause mortality and sudden cardiac death in patients with LV dys-function after MI?

Output: there was an inverse relation between body mass index and both all-cause mortality and sudden cardiac death in patients with LV dys-function after MI.807

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the inverse relation between body mass index and all-cause mortality and sudden cardiac death in patients with LV dys-function after MI?. ### Response: there was an inverse relation between body mass index and both all-cause mortality and sudden cardiac death in patients with LV dys-function after MI.807.


Instruction: In the SYNERGY trial of 9837 patients with NSTEMI, mortality was lower in morbidly obese patients, consistent with the "obesity paradox?"

Output: 807

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the SYNERGY trial of 9837 patients with NSTEMI, mortality was lower in morbidly obese patients, consistent with the "obesity paradox?". ### Response: 807.


Instruction: How much weight loss did a weight reduction study of obese and morbid obese patients following AMI result in?

Output: 0.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much weight loss did a weight reduction study of obese and morbid obese patients following AMI result in?. ### Response: 0.5%.


Instruction: What is the name of the phenomenon that has not been clarified?

Output: obe-sity paradox

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the phenomenon that has not been clarified?. ### Response: obe-sity paradox.


Instruction: How much weight loss did AMI result in in obese patients?

Output: 0.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much weight loss did AMI result in in obese patients?. ### Response: 0.5%.


Instruction: What was the weight loss rate in morbidly obese patients after 1 year?

Output: 3.5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the weight loss rate in morbidly obese patients after 1 year?. ### Response: 3.5%.


Instruction: How many drugs are available for weight reduction but have not been studied in patients fol-lowing NSTE-ACS?

Output: Two drugs, controlled-release phentermine/topiramate810 and lorcaserin,811

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many drugs are available for weight reduction but have not been studied in patients fol-lowing NSTE-ACS?. ### Response: Two drugs, controlled-release phentermine/topiramate810 and lorcaserin,811.


Instruction: Bariatric surgery has been successful in what?

Output: reducing cardiovascular risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bariatric surgery has been successful in what?. ### Response: reducing cardiovascular risk factors.


Instruction: What has been successful in reducing cardiovascular risk factors?

Output: Bariatric surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been successful in reducing cardiovascular risk factors?. ### Response: Bariatric surgery.


Instruction: What does the 2013 obesity CPG provide comprehensive strategies for?

Output: weight reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the 2013 obesity CPG provide comprehensive strategies for?. ### Response: weight reduction.


Instruction: Anti-neoplastic agents such as gemcitabine, sorafenib sunitinib, and 5-fluorouracil have been associated with what?

Output: coronary artery spasm or stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anti-neoplastic agents such as gemcitabine, sorafenib sunitinib, and 5-fluorouracil have been associated with what?. ### Response: coronary artery spasm or stenosis.


Instruction: Trastuzumab and other anti-cancer drugs may alter biomarker levels.

Output: 813,814

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Trastuzumab and other anti-cancer drugs may alter biomarker levels.. ### Response: 813,814.


Instruction: What can induce changes in the arterial wall?

Output: Antineoplastic agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can induce changes in the arterial wall?. ### Response: Antineoplastic agents.


Instruction: What can antineoplastic agents induce in the arterial wall?

Output: changes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can antineoplastic agents induce in the arterial wall?. ### Response: changes.


Instruction: What can modula-tors of inflammation promote atherogenesis?

Output: Antineoplastic agents can induce changes in the arterial wall

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can modula-tors of inflammation promote atherogenesis?. ### Response: Antineoplastic agents can induce changes in the arterial wall.


Instruction: What can be beneficial in improving the quality of NSTE-ACS care?

Output: Participation in a standardized quality-of-care data registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial in improving the quality of NSTE-ACS care?. ### Response: Participation in a standardized quality-of-care data registry.


Instruction: What is a standardized quality-of-care data registry designed to track?

Output: outcomes, complications, and performance measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a standardized quality-of-care data registry designed to track?. ### Response: outcomes, complications, and performance measures.


Instruction: What is crucial in the development of national systems for ACS?

Output: participation of key stakeholders to evaluate care using standardized performance and quality-improvement measures for ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is crucial in the development of national systems for ACS?. ### Response: participation of key stakeholders to evaluate care using standardized performance and quality-improvement measures for ACS.


Instruction: What is one of the quality-of-care data registries?

Output: AHA/ACC NSTE-ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the quality-of-care data registries?. ### Response: AHA/ACC NSTE-ACS.


Instruction: What is another quality-improvement program?

Output: Get With the Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another quality-improvement program?. ### Response: Get With the Guidelines.


Instruction: Chronic Heart Failure Diagnosing heart failure Diagnostic strategy Heart failure COPD Myocardial ischaemia NT-proBNP threshold: 125pg/ml £ 334 £ 1,096 £ 131

Output: Heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Chronic Heart Failure Diagnosing heart failure Diagnostic strategy Heart failure COPD Myocardial ischaemia NT-proBNP threshold: 125pg/ml £ 334 £ 1,096 £ 131. ### Response: Heart failure.


Instruction: What is the NT-proBNP threshold for heart failure?

Output: 125pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NT-proBNP threshold for heart failure?. ### Response: 125pg/ml.


Instruction: What is a non-heart failure population?

Output: Echo all

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a non-heart failure population?. ### Response: Echo all.


Instruction: What was the NT-proBNP threshold?

Output: 280pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the NT-proBNP threshold?. ### Response: 280pg/ml.


Instruction: What was done to the base case analysis?

Output: Multiple sensitivity analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was done to the base case analysis?. ### Response: Multiple sensitivity analyses.


Instruction: How was the time to representation extended?

Output: GP for false negatives

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the time to representation extended?. ### Response: GP for false negatives.


Instruction: HF -REF patients extended the time to representation to the GP for false negatives?

Output: prognostic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: HF -REF patients extended the time to representation to the GP for false negatives?. ### Response: prognostic.


Instruction: The prognostic differences for those with NT -proBNP levels above and below what level?

Output: 400pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The prognostic differences for those with NT -proBNP levels above and below what level?. ### Response: 400pg/ml.


Instruction: What did not lead to a change in the optimal strategy?

Output: the cost of NT -proBNP test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not lead to a change in the optimal strategy?. ### Response: the cost of NT -proBNP test.


Instruction: What did Verdu and Zaphiriou do?

Output: probabilistically

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Verdu and Zaphiriou do?. ### Response: probabilistically.


Instruction: When were u ndertaken?

Output: 2012 and Zaphiriou et al. 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were u ndertaken?. ### Response: 2012 and Zaphiriou et al. 2005.


Instruction: What was considered important that these were also run probabilistically?

Output: The average estimates for the sensitivity and specificity values for Zaphiriou were consistent with the original data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was considered important that these were also run probabilistically?. ### Response: The average estimates for the sensitivity and specificity values for Zaphiriou were consistent with the original data.


Instruction: When applying the ordinal logistic regression to the Verdu study data, the mean specificity values did not match what?

Output: the original s tudy values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When applying the ordinal logistic regression to the Verdu study data, the mean specificity values did not match what?. ### Response: the original s tudy values.


Instruction: What is the sensitivity of 125pg/ml?

Output: 1.00

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sensitivity of 125pg/ml?. ### Response: 1.00.


Instruction: What was the Verdu study run both probabilistically and deterministically?

Output: using the reported study data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Verdu study run both probabilistically and deterministically?. ### Response: using the reported study data.


Instruction: How were the average estimates for the sensitivity and specificity values for Zaphiriou run?

Output: probabilistically

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the average estimates for the sensitivity and specificity values for Zaphiriou run?. ### Response: probabilistically.


Instruction: What were the results of the analyses in detail in Appendix O?

Output: pres ented

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the results of the analyses in detail in Appendix O?. ### Response: pres ented.


Instruction: What was found to be the most cost effective NT -proBNP threshold?

Output: 280pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to be the most cost effective NT -proBNP threshold?. ### Response: 280pg/ml.


Instruction: What dominates 400pg/ml with higher mean QALYs and a lower mean cost?

Output: 280pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What dominates 400pg/ml with higher mean QALYs and a lower mean cost?. ### Response: 280pg/ml.


Instruction: What is the incremental cost effectiveness ratio of 280pg/ml compared to echo all?

Output: £5,952 per QALY gained

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the incremental cost effectiveness ratio of 280pg/ml compared to echo all?. ### Response: £5,952 per QALY gained.


Instruction: What was found to be the most cost effective NT?

Output: 280pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to be the most cost effective NT?. ### Response: 280pg/ml.


Instruction: A threshold of 400pg/ml produces both the highest incremental cost and what else?

Output: QALYs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A threshold of 400pg/ml produces both the highest incremental cost and what else?. ### Response: QALYs.


Instruction: What is the highest net monetary benefit at £20,000 per QALY?

Output: 400pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the highest net monetary benefit at £20,000 per QALY?. ### Response: 400pg/ml.


Instruction: What is the most cost eff ective diagnostic threshold for referral to echocardiography?

Output: 400pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most cost eff ective diagnostic threshold for referral to echocardiography?. ### Response: 400pg/ml.


Instruction: How much is the cost -effectiveness ratio of 400pg/ml versus 280pg per QALY?

Output: £ 9,842

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much is the cost -effectiveness ratio of 400pg/ml versus 280pg per QALY?. ### Response: £ 9,842.