Instruction: In patients with short QT syndrome and recurrent sustained VA, what can be useful?

Output: treatment with quinidine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with short QT syndrome and recurrent sustained VA, what can be useful?. ### Response: treatment with quinidine.


Instruction: How many studies were included in the review?

Output: 22

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included in the review?. ### Response: 22.


Instruction: Why was there no meta-analysis?

Output: heterogeneous nature of the interventions and populations in the included stu dies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there no meta-analysis?. ### Response: heterogeneous nature of the interventions and populations in the included stu dies.


Instruction: No meta -analysis was conducted due to the heterogeneous nature of the interventions and populations in what?

Output: stu dies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No meta -analysis was conducted due to the heterogeneous nature of the interventions and populations in what?. ### Response: stu dies.


Instruction: The studies were grouped into strata based on the population risk level (high, low) and the length of the intervention (long, mid, short).

Output: MDT clinic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The studies were grouped into strata based on the population risk level (high, low) and the length of the intervention (long, mid, short).. ### Response: MDT clinic.


Instruction: How many intervention types were there?

Output: four

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many intervention types were there?. ### Response: four.


Instruction: What type of MDT was not identified in the High risk Short category?

Output: Home -based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of MDT was not identified in the High risk Short category?. ### Response: Home -based.


Instruction: How many studies with high risk populations were included in the category of MDT clinic?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies with high risk populations were included in the category of MDT clinic?. ### Response: three.


Instruction: What was the outcome of all-cause hospitalisations?

Output: the evidence was inconsistent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of all-cause hospitalisations?. ### Response: the evidence was inconsistent.


Instruction: How did one study suggest a clinically important reduction?

Output: high quality evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did one study suggest a clinically important reduction?. ### Response: high quality evidence.


Instruction: How many studies did one of the studies suggest a clinically important reduction?

Output: 98

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did one of the studies suggest a clinically important reduction?. ### Response: 98.


Instruction: What was the confidence interval ranging from a decrease and increase in all-cause mortality?

Output: The evidence from both studies did not demonstrate a clear effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the confidence interval ranging from a decrease and increase in all-cause mortality?. ### Response: The evidence from both studies did not demonstrate a clear effect.


Instruction: How many studies showed a clinically important increase in prescribing of ACE inhibitors and beta-blockers?

Output: n=112

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies showed a clinically important increase in prescribing of ACE inhibitors and beta-blockers?. ### Response: n=112.


Instruction: What type of clinic No studies were identified in this category?

Output: Nurse -led or pharmacist -led clinic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of clinic No studies were identified in this category?. ### Response: Nurse -led or pharmacist -led clinic.


Instruction: How many studies were identified in the High risk, Mid -length Home -based MDT category?

Output: one study (n=72

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were identified in the High risk, Mid -length Home -based MDT category?. ### Response: one study (n=72.


Instruction: What type of intervention was used in the study with a high risk population?

Output: mid -length MDT clinic interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention was used in the study with a high risk population?. ### Response: mid -length MDT clinic interventions.


Instruction: What was the clinically important reduction in hospitalisations?

Output: high quality evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the clinically important reduction in hospitalisations?. ### Response: high quality evidence.


Instruction: What was low quality evidence?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was low quality evidence?. ### Response: moderate.


Instruction: Mortality did not demonstrate a clear effect on what?

Output: confidence interval ranging from a decrease and increase in all -cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Mortality did not demonstrate a clear effect on what?. ### Response: confidence interval ranging from a decrease and increase in all -cause mortality.


Instruction: How many studies were included in the category of MDT clinic?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included in the category of MDT clinic?. ### Response: three.


Instruction: What was the quality of the evidence on hospitalisations?

Output: inconsistent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence on hospitalisations?. ### Response: inconsistent.


Instruction: How many of the studies included high risk populations exposed to MDT interventions?

Output: three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the studies included high risk populations exposed to MDT interventions?. ### Response: three.


Instruction: How many studies suggested a clinically important reduction?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies suggested a clinically important reduction?. ### Response: two.


Instruction: What was the third study suggesting no cl inical difference?

Output: n=200

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the third study suggesting no cl inical difference?. ### Response: n=200.


Instruction: Evidence on mortality was low to what quality?

Output: very low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence on mortality was low to what quality?. ### Response: very low.


Instruction: What does not demonstrate a clear effect with the confidence interval?

Output: Mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not demonstrate a clear effect with the confidence interval?. ### Response: Mortality.


Instruction: What is chronic atrial fibrillation?

Output: Thromb Res . 2007;120(2):201-206.84

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is chronic atrial fibrillation?. ### Response: Thromb Res . 2007;120(2):201-206.84.


Instruction: What is tinzaparin versus heparin?

Output: subcut aneousunfractionated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tinzaparin versus heparin?. ### Response: subcut aneousunfractionated.


Instruction: What is the name of the study that compares tinzaparin with subcut aneousunfractionated heparin in elderly patients with acute deep vein thrombosis?

Output: Innohep® in Renal Insufficienc y Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares tinzaparin with subcut aneousunfractionated heparin in elderly patients with acute deep vein thrombosis?. ### Response: Innohep® in Renal Insufficienc y Study.


Instruction: When was the Innohep® in Renal Insufficiency Study conducted?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Innohep® in Renal Insufficiency Study conducted?. ### Response: 2011.


Instruction: What does enoxaparin do for obese and renal impairment patients?

Output: Dosage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does enoxaparin do for obese and renal impairment patients?. ### Response: Dosage.


Instruction: What is the effect of antifactor Xa concentrations on renal function?

Output: Correlation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of antifactor Xa concentrations on renal function?. ### Response: Correlation.


Instruction: What is a pharmacokinetic program for adjusting enoxaparin in renal impairment?

Output: Retrospective evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pharmacokinetic program for adjusting enoxaparin in renal impairment?. ### Response: Retrospective evaluation.


Instruction: What is the safety profile of tinzaparin administered once daily at a standard curative dose in two hundred and fifty grams?

Output: 175 anti-Xa IU/kg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the safety profile of tinzaparin administered once daily at a standard curative dose in two hundred and fifty grams?. ### Response: 175 anti-Xa IU/kg.


Instruction: What is the standard curative dose in two hundred v eryelderly patients?

Output: tinzaparin administered once daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the standard curative dose in two hundred v eryelderly patients?. ### Response: tinzaparin administered once daily.


Instruction: When did Drug Saf issue its 25(10):725-733.90?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Drug Saf issue its 25(10):725-733.90?. ### Response: 2002.


Instruction: What does Renal function, peak anti Xa levels and enoxaparin do?

Output: dosing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Renal function, peak anti Xa levels and enoxaparin do?. ### Response: dosing.


Instruction: What is tinzaparin?

Output: Innohep

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tinzaparin?. ### Response: Innohep.


Instruction: How many anti-Xa IU/kg is given to elderly patients?

Output: 175

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many anti-Xa IU/kg is given to elderly patients?. ### Response: 175.


Instruction: What is the effect of enoxaparin on peak and trough levels of antifactor Xa?

Output: Renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of enoxaparin on peak and trough levels of antifactor Xa?. ### Response: Renal function.


Instruction: What does enoxaparin measure on peak and trough levels of antifactor Xa in patients with a creatinine clearance of less than 30 mL/min?

Output: Effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does enoxaparin measure on peak and trough levels of antifactor Xa in patients with a creatinine clearance of less than 30 mL/min?. ### Response: Effect.


Instruction: What is monitored in impaired and morbidly obese patients?

Output: anti-factor Xa levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is monitored in impaired and morbidly obese patients?. ### Response: anti-factor Xa levels.


Instruction: What is enoxaparin dosage adjustment in patients with severe renal failure?

Output: antifactor xa concentrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is enoxaparin dosage adjustment in patients with severe renal failure?. ### Response: antifactor xa concentrations.


Instruction: When was antifactor xa concentrations and sa fety measured?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was antifactor xa concentrations and sa fety measured?. ### Response: 2007.


Instruction: How are low-molecular-weight heparins appropriately dosed in patients with CKD stage 3 to 5?

Output: Are low-molecular-weight heparins appropriately dosed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are low-molecular-weight heparins appropriately dosed in patients with CKD stage 3 to 5?. ### Response: Are low-molecular-weight heparins appropriately dosed.


Instruction: What does Thorevska N, Amoateng-Adjepong Y, Sabahi R, et al. compare in hospitalized patients with renal insufficiency?

Output: bleeding rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Thorevska N, Amoateng-Adjepong Y, Sabahi R, et al. compare in hospitalized patients with renal insufficiency?. ### Response: bleeding rates.


Instruction: What is the difference in bleeding rates between heparin and enoxaparin?

Output: unfractionated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference in bleeding rates between heparin and enoxaparin?. ### Response: unfractionated.


Instruction: When was Chest.125(3):856-863.97 published?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Chest.125(3):856-863.97 published?. ### Response: 2004.


Instruction: What does Barras M. Anti-Xa assays do?

Output: Anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Barras M. Anti-Xa assays do?. ### Response: Anticoagulation.


Instruction: What does the WorkGroup believe not all patients and providers will value?

Output: theinformation provided by ABPM and HBPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the WorkGroup believe not all patients and providers will value?. ### Response: theinformation provided by ABPM and HBPM.


Instruction: Prior studies have found that a majority of patients prefer HBPM to what?

Output: ABPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prior studies have found that a majority of patients prefer HBPM to what?. ### Response: ABPM.


Instruction: What do most patients prefer to HBPM?

Output: ABPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do most patients prefer to HBPM?. ### Response: ABPM.


Instruction: What has been reported by patients to result in fewer disturbances in their daily activities?

Output: BP measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been reported by patients to result in fewer disturbances in their daily activities?. ### Response: BP measurements.


Instruction: What is ABPM cost-saving and cost-effective for the management of high BP in the general population?

Output: Resource use and costs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ABPM cost-saving and cost-effective for the management of high BP in the general population?. ### Response: Resource use and costs.


Instruction: What type of studies were not conducted in CKD?

Output: observational studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of studies were not conducted in CKD?. ### Response: observational studies.


Instruction: What is the cost-effectiveness of HBPM for management of high BP?

Output: unclear

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of HBPM for management of high BP?. ### Response: unclear.


Instruction: What may be less inclined to follow this recommendation?

Output: Persons with limited ﬁnancial resources

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be less inclined to follow this recommendation?. ### Response: Persons with limited ﬁnancial resources.


Instruction: The use of ABPM orHBPM will depend on the resources available.

Output: lack ofdevice availability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The use of ABPM orHBPM will depend on the resources available.. ### Response: lack ofdevice availability.


Instruction: Staff should be trained to conduct what?

Output: ABPM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Staff should be trained to conduct what?. ### Response: ABPM.


Instruction: What does ABPM require every 1 - 2 years?

Output: recalibration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ABPM require every 1 - 2 years?. ### Response: recalibration.


Instruction: There are no standardizedprotocols for calibrating what?

Output: HBPM devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are no standardizedprotocols for calibrating what?. ### Response: HBPM devices.


Instruction: What should providers ask patients to bring their HBPM device to the office to compare?

Output: BP values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should providers ask patients to bring their HBPM device to the office to compare?. ### Response: BP values.


Instruction: What does this recommendation place a high value on informing anindividual’s overall BP pro file and identifying persons withhigh CV disease risks related to highBP?

Output: 42Rationale

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does this recommendation place a high value on informing anindividual’s overall BP pro file and identifying persons withhigh CV disease risks related to highBP?. ### Response: 42Rationale.


Instruction: What does high BP recommenda-tion place a lower value on?

Output: potential lack ofdevice availability, cost, and patient burden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does high BP recommenda-tion place a lower value on?. ### Response: potential lack ofdevice availability, cost, and patient burden.


Instruction: What does observational studies indicate about highBP?

Output: the diagnosis of highBP and BP control status differs for a high proportion ofadults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does observational studies indicate about highBP?. ### Response: the diagnosis of highBP and BP control status differs for a high proportion ofadults.


Instruction: What do observational studies indicate a stronger associ-ation of out-of-fice BP measurements with CV and kidneyoutcomes?

Output: diagnosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do observational studies indicate a stronger associ-ation of out-of-fice BP measurements with CV and kidneyoutcomes?. ### Response: diagnosis.


Instruction: What is a potential treatment for masked uncontrolledhypertension?

Output: Antihy-pertensive medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential treatment for masked uncontrolledhypertension?. ### Response: Antihy-pertensive medication.


Instruction: What has potential treatment implications?

Output: Identi ﬁcation of “white-coat ”hypertension, masked hy-pertension, the “white-coat ”effect, and masked uncontrolledhypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has potential treatment implications?. ### Response: Identi ﬁcation of “white-coat ”hypertension, masked hy-pertension, the “white-coat ”effect, and masked uncontrolledhypertension.


Instruction: What can be considered for patients with substantial masked uncontrolled hypertension?

Output: Antihy-pertensive medication initiation and intensi ﬁcation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be considered for patients with substantial masked uncontrolled hypertension?. ### Response: Antihy-pertensive medication initiation and intensi ﬁcation.


Instruction: How can antihy-pertensive medication initiation and intensi fication be considered?

Output: patients with substantial masked hypertensionand masked uncontrolled hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can antihy-pertensive medication initiation and intensi fication be considered?. ### Response: patients with substantial masked hypertensionand masked uncontrolled hypertension.


Instruction: What is resynchronization therapy used for in heart transplant recipients?

Output: results of a national survey

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is resynchronization therapy used for in heart transplant recipients?. ### Response: results of a national survey.


Instruction: What is the name of the study that found out the results of a national survey?

Output: J Heart Lung Transplant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that found out the results of a national survey?. ### Response: J Heart Lung Transplant.


Instruction: In what year was the J Heart Lung Transplant published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the J Heart Lung Transplant published?. ### Response: 2009.


Instruction: How many patients received heart transplants in 2009?

Output: 28

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients received heart transplants in 2009?. ### Response: 28.


Instruction: What is the tem-poral trend of sudden cardiac death after heart transplantation?

Output: 11:1684–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the tem-poral trend of sudden cardiac death after heart transplantation?. ### Response: 11:1684–.


Instruction: What is Vaseghi M, Lellouche N, Ritter H, et al.?

Output: Mode and mechanisms of death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Vaseghi M, Lellouche N, Ritter H, et al.?. ### Response: Mode and mechanisms of death.


Instruction: How is death after a heart transplant treated?

Output: resynchronization therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is death after a heart transplant treated?. ### Response: resynchronization therapy.


Instruction: What is heart transplantation?

Output: orthotopic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is heart transplantation?. ### Response: orthotopic.


Instruction: What is the name of the disease that causes increased mortality in adults with myotonic dystrophy type 1?

Output: left ven-tricular systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes increased mortality in adults with myotonic dystrophy type 1?. ### Response: left ven-tricular systolic dysfunction.


Instruction: How many people died from heart failure in 2010?

Output: 41

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people died from heart failure in 2010?. ### Response: 41.


Instruction: What is the mechanism of sustained ventricular tachycardia in myotonic dystrophy implica-tions for catheter ablation?

Output: Mechanisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mechanism of sustained ventricular tachycardia in myotonic dystrophy implica-tions for catheter ablation?. ### Response: Mechanisms.


Instruction: What is anselme F, Moubarak G, Savoure A, et al.?

Output: Implantable cardioverter-defibrillators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is anselme F, Moubarak G, Savoure A, et al.?. ### Response: Implantable cardioverter-defibrillators.


Instruction: What is a risk factor for malignant ventricular arrhythmias in lamin A/C mutation carriers?

Output: sudden death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for malignant ventricular arrhythmias in lamin A/C mutation carriers?. ### Response: sudden death.


Instruction: What is the primary prevention of sud-den death in children?

Output: lamin A/C gene mutations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary prevention of sud-den death in children?. ### Response: lamin A/C gene mutations.


Instruction: What is primary prevention of sud-den death in patients with lamin A/C gene mutations?

Output: Meune C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is primary prevention of sud-den death in patients with lamin A/C gene mutations?. ### Response: Meune C.


Instruction: What is the N Engl J Med. 2006:354:209-10?

Output: C gene mutations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2006:354:209-10?. ### Response: C gene mutations.


Instruction: Who is a Pasotti M, Klersy C, Pilotto A, et al.?

Output: C gene mutations. N Engl J Med. 2006;354:209–10. S7.8-6. Pasotti M, Klersy C, Pilotto A, et al. Long-term outcome and risk stratification in dilated cardiolaminopathies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Pasotti M, Klersy C, Pilotto A, et al.?. ### Response: C gene mutations. N Engl J Med. 2006;354:209–10. S7.8-6. Pasotti M, Klersy C, Pilotto A, et al. Long-term outcome and risk stratification in dilated cardiolaminopathies.


Instruction: How many carriers of LMNA gene mutations did van Berlo JH, de Voogt WG, van der Kooi AJ, et al. Meta-analysis of clinical characteristics of 299 carriers of lamin A/C mutations?

Output: 299

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many carriers of LMNA gene mutations did van Berlo JH, de Voogt WG, van der Kooi AJ, et al. Meta-analysis of clinical characteristics of 299 carriers of lamin A/C mutations?. ### Response: 299.


Instruction: What does J Mol Med. 2005;83:79–83.

Output: high risk of sudden death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does J Mol Med. 2005;83:79–83.. ### Response: high risk of sudden death.


Instruction: What is the role of ICD in sudden death?

Output: preventing sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of ICD in sudden death?. ### Response: preventing sudden cardiac death.


Instruction: What is the role of ICD in preventing sudden cardiac death in Emery-Dreifuss muscular dystrophy with preserved myocardial func-tion?

Output: 2013 ESC guidelines on cardiac pacing and cardiac resynchro-nization therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of ICD in preventing sudden cardiac death in Emery-Dreifuss muscular dystrophy with preserved myocardial func-tion?. ### Response: 2013 ESC guidelines on cardiac pacing and cardiac resynchro-nization therapy.


Instruction: What are the 2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy?

Output: ICD role in preventing sudden cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy?. ### Response: ICD role in preventing sudden cardiac death.


Instruction: Electrocardiographic abnormalities and sudden death in myotonic dystrophy type 1?

Output: N Engl J Med. 2008;358:2688–97

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Electrocardiographic abnormalities and sudden death in myotonic dystrophy type 1?. ### Response: N Engl J Med. 2008;358:2688–97.


Instruction: N Engl J Med. 2008;358:2688–97.

Output: myotonic dystrophy type 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: N Engl J Med. 2008;358:2688–97.. ### Response: myotonic dystrophy type 1.


Instruction: What is the evolution of infrahissian conduction time in?

Output: myotonic dystrophy patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the evolution of infrahissian conduction time in?. ### Response: myotonic dystrophy patients.


Instruction: What is a clinical predictor of con-duction disease progression in type I myotonic muscular dystrophy?

Output: sustained ventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a clinical predictor of con-duction disease progression in type I myotonic muscular dystrophy?. ### Response: sustained ventricular tachycardia.


Instruction: What is the name of the 2011 study?

Output: Pacing Clin Electrophysiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2011 study?. ### Response: Pacing Clin Electrophysiol.


Instruction: What type of muscular dystrophy are patients with?

Output: myotonic dystrophy type 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of muscular dystrophy are patients with?. ### Response: myotonic dystrophy type 1.


Instruction: What is the name of the medical journal that studies myotonic muscular dysfunction type I and II?

Output: JAMA Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the medical journal that studies myotonic muscular dysfunction type I and II?. ### Response: JAMA Cardiology.


Instruction: What should prescriber see in t he summar y of pr oduct charact eristics?

Output: the manuf actur er's advice on use in pr egnancy .

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should prescriber see in t he summar y of pr oduct charact eristics?. ### Response: the manuf actur er's advice on use in pr egnancy ..


Instruction: The pr escriber should follow relevant prfessional guidance, taking full r esponsibility f or the decision?

Output: voided

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The pr escriber should follow relevant prfessional guidance, taking full r esponsibility f or the decision?. ### Response: voided.


Instruction: What should be obtained and documented?

Output: Inf ormed consent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be obtained and documented?. ### Response: Inf ormed consent.


Instruction: Who issued a drug saf ety in 2014?

Output: Medicines and Healt hcare product s Regulat ory Agency (MHRA)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who issued a drug saf ety in 2014?. ### Response: Medicines and Healt hcare product s Regulat ory Agency (MHRA).


Instruction: What agency issued a drug saf ety updat e on ACE inhibit ors and angiot ensin II recept or antagonist?

Output: MHRA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What agency issued a drug saf ety updat e on ACE inhibit ors and angiot ensin II recept or antagonist?. ### Response: MHRA.


Instruction: What stat es should use in w omen who ar e planning pregnancy be a voided?

Output: capt opril, enalapril, or quinapril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What stat es should use in w omen who ar e planning pregnancy be a voided?. ### Response: capt opril, enalapril, or quinapril.


Instruction: What should be a voided unless absolutly necessar y?

Output: Use in w omen who ar e planning pr egnancy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be a voided unless absolutly necessar y?. ### Response: Use in w omen who ar e planning pr egnancy.


Instruction: When did some brands of nif edipine w ere specifically contraindicat ed during pr egnancy?

Output: June 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did some brands of nif edipine w ere specifically contraindicat ed during pr egnancy?. ### Response: June 2019.


Instruction: What is nif edipine specifically contraindicat ed during pregnancy?

Output: some brands of nif edipine w ere specifically contraindicat ed during pr egnancy b y the manuf actur er in it s summar y of pr oduct charact eristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is nif edipine specifically contraindicat ed during pregnancy?. ### Response: some brands of nif edipine w ere specifically contraindicat ed during pr egnancy b y the manuf actur er in it s summar y of pr oduct charact eristics.


Instruction: R efer to the individual summaries of pr oduct charact eristics?

Output: magnesium sulf ate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: R efer to the individual summaries of pr oduct charact eristics?. ### Response: magnesium sulf ate.


Instruction: Who has issued a warning about t he risk of sk eletal eff ects in neonat e following pr olonged or r epeat use of magnesium sulfate in pr egnancy?

Output: The MHRA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has issued a warning about t he risk of sk eletal eff ects in neonat e following pr olonged or r epeat use of magnesium sulfate in pr egnancy?. ### Response: The MHRA.


Instruction: What has been associat ed with h skeletal adv erse eff ects?

Output: magnesium sulf

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been associat ed with h skeletal adv erse eff ects?. ### Response: magnesium sulf.


Instruction: How long does mat ernal administration of magnesium sulf ate for in pr egnancy?

Output: 5–7  days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does mat ernal administration of magnesium sulf ate for in pr egnancy?. ### Response: 5–7  days.


Instruction: What is h ypermagnesemia in neonat es?

Output: pocalcaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is h ypermagnesemia in neonat es?. ### Response: pocalcaemia.


Instruction: What should be considered if use of magnesium sulfate in pregnancy is pr olonged or r epeat?

Output: abnormal calcium and magnesium le vels and sk eletal adv erse effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered if use of magnesium sulfate in pregnancy is pr olonged or r epeat?. ### Response: abnormal calcium and magnesium le vels and sk eletal adv erse effects.


Instruction: When did the MHRA issue a drug safa?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the MHRA issue a drug safa?. ### Response: 2014.


Instruction: When did the MHRA issue a drug saf ety updat e on ACE inhibit ors and angiot ensin II recept or antagonist?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the MHRA issue a drug saf ety updat e on ACE inhibit ors and angiot ensin II recept or antagonist?. ### Response: 2014.


Instruction: When was a subsequent clarification issued?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a subsequent clarification issued?. ### Response: 2014.


Instruction: When was this clarification issued?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this clarification issued?. ### Response: 2014.


Instruction: What is generally not recommended for use by breastf eeding mot hers?

Output: A CE inhibit ors and angiot ensin  II recept or antagonist s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is generally not recommended for use by breastf eeding mot hers?. ### Response: A CE inhibit ors and angiot ensin  II recept or antagonist s.


Instruction: What is not absolut ely contraindicat ed?

Output: A CE inhibit ors and angiot ensin  II recept or antagonist s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not absolut ely contraindicat ed?. ### Response: A CE inhibit ors and angiot ensin  II recept or antagonist s.


Instruction: What do hcare professionals ma y prescribe during breastf eeding?

Output: t hese medicines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do hcare professionals ma y prescribe during breastf eeding?. ### Response: t hese medicines.


Instruction: What should be considered if an A CE inhibits or is necessary for the mot her?

Output: the use of capt opril, enalapril, or quinapril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered if an A CE inhibits or is necessary for the mot her?. ### Response: the use of capt opril, enalapril, or quinapril.


Instruction: What is recommended for breastf eeding older infants?

Output: capt opril, enalapril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for breastf eeding older infants?. ### Response: capt opril, enalapril.


Instruction: Hyper tension in pregnancy: diagnosis and management (NG133) NICE 2023. Subject t o Notice of right s (http://www.nice.or g.uk/t erms-and-conditions#notice-of-right s)

Output: All right s reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyper tension in pregnancy: diagnosis and management (NG133) NICE 2023. Subject t o Notice of right s (http://www.nice.or g.uk/t erms-and-conditions#notice-of-right s). ### Response: All right s reserved.


Instruction: How much did the odds of a stroke decrease for each 3-mol/L decrease in homocysteine?

Output: 24%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much did the odds of a stroke decrease for each 3-mol/L decrease in homocysteine?. ### Response: 24%.


Instruction: What is a meta-anal-ysis of 29 studies?

Output: comparing the MTHFR C677T genotype between 4454 stroke patients and 7586 control subjects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-anal-ysis of 29 studies?. ### Response: comparing the MTHFR C677T genotype between 4454 stroke patients and 7586 control subjects.


Instruction: How many studies compared the MTHFR C677T genotype between 4454 stroke patients and 7586 control subjects?

Output: 29

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies compared the MTHFR C677T genotype between 4454 stroke patients and 7586 control subjects?. ### Response: 29.


Instruction: What type of randomization found increased stroke in those with the TT genotype?

Output: mendelian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of randomization found increased stroke in those with the TT genotype?. ### Response: mendelian.


Instruction: What are the B complex vitamins pyridoxine, cobalamin, and folic acid?

Output: B6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the B complex vitamins pyridoxine, cobalamin, and folic acid?. ### Response: B6.


Instruction: What is the B12 vitamin?

Output: cobalamin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the B12 vitamin?. ### Response: cobalamin.


Instruction: Folic acid intake is associated with reduced risk of what?

Output: ischemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Folic acid intake is associated with reduced risk of what?. ### Response: ischemic stroke.


Instruction: What did B complex vitamin supplementation do in a clinical trial of healthy adults without diabetes mellitus and CVD?

Output: decreased carotid IMT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did B complex vitamin supplementation do in a clinical trial of healthy adults without diabetes mellitus and CVD?. ### Response: decreased carotid IMT.


Instruction: What was the baseline plasma homocysteine  9.1 mol/L?

Output: 9.1 μ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the baseline plasma homocysteine  9.1 mol/L?. ### Response: 9.1 μ.


Instruction: What did a meta-analysis of 10 random-ized trials of folic acid find?

Output: treatment decreased IMT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a meta-analysis of 10 random-ized trials of folic acid find?. ### Response: treatment decreased IMT.


Instruction: What did the treatment of IMT decrease but with substantial heterogeneity resulting from larger effects at higher baseline IMTs?

Output: homocysteine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the treatment of IMT decrease but with substantial heterogeneity resulting from larger effects at higher baseline IMTs?. ### Response: homocysteine.


Instruction: What did a substudy of the Vitamins to Prevent Stroke (VITATOPS) trial report?

Output: 782

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a substudy of the Vitamins to Prevent Stroke (VITATOPS) trial report?. ### Response: 782.


Instruction: What did most trials of patients with established atherosclerotic vas-cular disease find no benefit of?

Output: homocysteine lower -ing by B complex vitamin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did most trials of patients with established atherosclerotic vas-cular disease find no benefit of?. ### Response: homocysteine lower -ing by B complex vitamin therapy.


Instruction: What did the Vitamin Intervention for Stroke Prevention (VISP) trial show did not affect the risk of recurrent isch-emic stroke?

Output: therapy with high doses of vitamin B6, vitamin B12, and folic acid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Vitamin Intervention for Stroke Prevention (VISP) trial show did not affect the risk of recurrent isch-emic stroke?. ### Response: therapy with high doses of vitamin B6, vitamin B12, and folic acid.


Instruction: What did high doses of vitamin B6, vitamin B12 and folic acid not affect?

Output: the risk of recurrent isch-emic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did high doses of vitamin B6, vitamin B12 and folic acid not affect?. ### Response: the risk of recurrent isch-emic stroke.


Instruction: What did the low-dose formulation of B complex vitamins not reduce in 2 Norwegian trials?

Output: mortal-ity or cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the low-dose formulation of B complex vitamins not reduce in 2 Norwegian trials?. ### Response: mortal-ity or cardiovascular events.


Instruction: What was the other trial of patients with coronary artery disease or aortic stenosis?

Output: Women’s Antioxidant and Folic Acid Cardiovascular Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the other trial of patients with coronary artery disease or aortic stenosis?. ### Response: Women’s Antioxidant and Folic Acid Cardiovascular Study.


Instruction: In the Women’s Antioxidant and Antioxidants trials, what did not reduce mortality?

Output: B complex vitamins

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the Women’s Antioxidant and Antioxidants trials, what did not reduce mortality?. ### Response: B complex vitamins.


Instruction: What is one of the most common cardiovascular events?

Output: stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the most common cardiovascular events?. ### Response: stroke.


Instruction: What did the WAFACS show about B complex vitamins?

Output: did not alter the risk of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the WAFACS show about B complex vitamins?. ### Response: did not alter the risk of stroke.


Instruction: How many subjects were in the VITATOPS trial?

Output: 8164

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many subjects were in the VITATOPS trial?. ### Response: 8164.


Instruction: How many subjects with recent stroke or TIA were randomized to vitamin B6, vitamin B12, and folic acid versus placebo?

Output: 8164

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many subjects with recent stroke or TIA were randomized to vitamin B6, vitamin B12, and folic acid versus placebo?. ### Response: 8164.


Instruction: How long were the subjects followed up for?

Output: 3.4 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long were the subjects followed up for?. ### Response: 3.4 years.


Instruction: What did the study find no effect of B vitamin supple-mentation on risk of stroke?

Output: VITATOPS trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the study find no effect of B vitamin supple-mentation on risk of stroke?. ### Response: VITATOPS trial.


Instruction: What is the HR of VITATOPS?

Output: 0.92

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the HR of VITATOPS?. ### Response: 0.92.


Instruction: What was the 95% confidence interval?

Output: 1.11–1.43

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 95% confidence interval?. ### Response: 1.11–1.43.


Instruction: How many sub-jects were not taking antiplatelet medication?

Output: 1463

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sub-jects were not taking antiplatelet medication?. ### Response: 1463.


Instruction: What is the name of the document that describes car diagnostics?

Output: Personalised package

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that describes car diagnostics?. ### Response: Personalised package.


Instruction: What is a car diac function?

Output: Assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a car diac function?. ### Response: Assessment.


Instruction: What is a personalised package of car e and inf ormation?

Output: 9 1.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a personalised package of car e and inf ormation?. ### Response: 9 1.4.


Instruction: How many 1.5 Referral f or specialised management?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many 1.5 Referral f or specialised management?. ### Response: 10.


Instruction: Stroke prevention?

Output: f or resear ch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stroke prevention?. ### Response: f or resear ch.


Instruction: Rat and rh ythm contr ol?

Output: Management f or people pr esenting acut ely wit h atrial fibrillation ........................................... 20 1.9 Initial management of str oke and atrial fibrillation ..................................................................... 22 1.10 Pr eventing and managing post operativ e atrial fibrillation ....................................................... 23 1.11 St opping anticoagulation ............................................................................................................. 25 Terms used in t his guideline ............................................................................................................... 25 Recommendations f or resear ch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Rat and rh ythm contr ol?. ### Response: Management f or people pr esenting acut ely wit h atrial fibrillation ........................................... 20 1.9 Initial management of str oke and atrial fibrillation ..................................................................... 22 1.10 Pr eventing and managing post operativ e atrial fibrillation ....................................................... 23 1.11 St opping anticoagulation ............................................................................................................. 25 Terms used in t his guideline ............................................................................................................... 25 Recommendations f or resear ch.


Instruction: How many terms are used in t his guideline?

Output: 25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many terms are used in t his guideline?. ### Response: 25.


Instruction: How many Recommendations f or resear?

Output: 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Recommendations f or resear?. ### Response: 27.


Instruction: What are the key recommendations for f or resear ch?

Output: 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the key recommendations for f or resear ch?. ### Response: 27.


Instruction: What is the risk of stroke?

Output: 31 Bleeding risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of stroke?. ### Response: 31 Bleeding risk.


Instruction: What is a direct renin inhibitor versusplacebo?

Output: Adults with CKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a direct renin inhibitor versusplacebo?. ### Response: Adults with CKD.


Instruction: What is an aliskiren versus ACEi or ARBTable?

Output: ACEi DARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an aliskiren versus ACEi or ARBTable?. ### Response: ACEi DARB.


Instruction: Adults with diabetes and CKD, high-dose potassium binder versus what?

Output: low-dosepotassium binder

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults with diabetes and CKD, high-dose potassium binder versus what?. ### Response: low-dosepotassium binder.


Instruction: What type of diet are kidney transplant recipients compared to?

Output: low-salt

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diet are kidney transplant recipients compared to?. ### Response: low-salt.


Instruction: What is the difference between a Mediterranean diet and a low-fat diet?

Output: Kidney transplant recipients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between a Mediterranean diet and a low-fat diet?. ### Response: Kidney transplant recipients.


Instruction: Kidney transplant recipients, ARB versus calcium channel blockersTable S94.

Output: ACEi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kidney transplant recipients, ARB versus calcium channel blockersTable S94.. ### Response: ACEi.


Instruction: What is ACEi versus ARBTable Table S95?

Output: ACEi Dcalcium channel blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACEi versus ARBTable Table S95?. ### Response: ACEi Dcalcium channel blockers.


Instruction: What are kidney transplant recipients comparing to?

Output: low-salt diet versus usual or normal-salt dietTable S90. Kidney transplant recipients, Mediterranean diet versus low-fat diet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are kidney transplant recipients comparing to?. ### Response: low-salt diet versus usual or normal-salt dietTable S90. Kidney transplant recipients, Mediterranean diet versus low-fat diet.


Instruction: Channel blockers versus calcium channel blockers aloneTable S97.

Output: ACEi Dcalcium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Channel blockers versus calcium channel blockers aloneTable S97.. ### Response: ACEi Dcalcium.


Instruction: Kidney transplant recipients, ACEi DARB versus ARB alone Table S99.

Output: placebo or no treatmentTable S100

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kidney transplant recipients, ACEi DARB versus ARB alone Table S99.. ### Response: placebo or no treatmentTable S100.


Instruction: What are kidney transplant recipients referred to as?

Output: ACE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are kidney transplant recipients referred to as?. ### Response: ACE.


Instruction: What is a kidney transplant recipient called?

Output: ACEi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a kidney transplant recipient called?. ### Response: ACEi.


Instruction: What is ACEi versus?

Output: calcium channel blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACEi versus?. ### Response: calcium channel blockers.


Instruction: What is ARB versus beta-blocker?

Output: calcium channel blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ARB versus beta-blocker?. ### Response: calcium channel blockers.


Instruction: Which kidney transplant recipients have calcium channel blockers versus thiazide?

Output: Kidney transplant recipients, calcium channel blockers versus thiazideTable S106

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which kidney transplant recipients have calcium channel blockers versus thiazide?. ### Response: Kidney transplant recipients, calcium channel blockers versus thiazideTable S106.


Instruction: What is the difference between channel blockers and thiazide?

Output: calcium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between channel blockers and thiazide?. ### Response: calcium.


Instruction: What are the differences between kidney transplant recipients and placebo?

Output: no treatment, or standard of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between kidney transplant recipients and placebo?. ### Response: no treatment, or standard of care.


Instruction: Where is Kidney International located?

Output: 2021) 99, S1–S87

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Kidney International located?. ### Response: 2021) 99, S1–S87.


Instruction: What does not apply to non-life-threatening bleeding?

Output: recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not apply to non-life-threatening bleeding?. ### Response: recommendation.


Instruction: What did we find no systematic review of?

Output: this question

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we find no systematic review of?. ### Response: this question.


Instruction: How many studies did we identify that addressed this question?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did we identify that addressed this question?. ### Response: 3.


Instruction: How many patients received idarucizumab?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients received idarucizumab?. ### Response: none.


Instruction: What did we combine the number of events and the total number of patients from the 3studies to calculate?

Output: a relative effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we combine the number of events and the total number of patients from the 3studies to calculate?. ### Response: a relative effect.


Instruction: How many studies included patients receiving dabigatran presenting with life-threatening bleeding?

Output: 1study195

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies included patients receiving dabigatran presenting with life-threatening bleeding?. ### Response: 1study195.


Instruction: What is urgently needed for invasive procedures?

Output: dabigatran reversal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is urgently needed for invasive procedures?. ### Response: dabigatran reversal.


Instruction: Allstudies reported the outcomes of life-threatening bleeding associ-ated with what?

Output: dabigatran therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Allstudies reported the outcomes of life-threatening bleeding associ-ated with what?. ### Response: dabigatran therapy.


Instruction: What is shown online at https://dbep.gradepro.org/profile/b1deb68f-2ed2-4734-bb86-0a66117969cd?

Output: EtD framework

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shown online at https://dbep.gradepro.org/profile/b1deb68f-2ed2-4734-bb86-0a66117969cd?. ### Response: EtD framework.


Instruction: What may or may not reduce themortality risk?

Output: Idarucizumab administration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may or may not reduce themortality risk?. ### Response: Idarucizumab administration.


Instruction: What is the RR of Idarucizumab?

Output: 0.47

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the RR of Idarucizumab?. ### Response: 0.47.


Instruction: What is the risk of life-threatening bleeding during dabigatran therapy?

Output: death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of life-threatening bleeding during dabigatran therapy?. ### Response: death.


Instruction: What are the CIs very wide and include large risk reductions and increases?

Output: Harms and burden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the CIs very wide and include large risk reductions and increases?. ### Response: Harms and burden.


Instruction: How many VTE events were reported following idarucizumab administration in 1 study?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many VTE events were reported following idarucizumab administration in 1 study?. ### Response: 5.


Instruction: What was not possible because there were no VTEs in the comparison group?

Output: Estimating the relative and absolute risk estimates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not possible because there were no VTEs in the comparison group?. ### Response: Estimating the relative and absolute risk estimates.


Instruction: The certainty in theseestimated effects is what?

Output: very low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The certainty in theseestimated effects is what?. ### Response: very low.


Instruction: What is the certainty in theseestimated effects?

Output: very low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the certainty in theseestimated effects?. ### Response: very low.


Instruction: The acquisitioncost of idarucizumab is considerable, although no formal economicanalyses are available?

Output: the cost likely outweighs the potential benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The acquisitioncost of idarucizumab is considerable, although no formal economicanalyses are available?. ### Response: the cost likely outweighs the potential benefit.


Instruction: There is very low certainty evidence for a net health benefit from using what drug?

Output: Idarucizumab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is very low certainty evidence for a net health benefit from using what drug?. ### Response: Idarucizumab.


Instruction: What is the benefit of usingidarucizumab to manage life-threatening bleeding for patients re-ceiving dabigatran therapy for VTE?

Output: net health benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of usingidarucizumab to manage life-threatening bleeding for patients re-ceiving dabigatran therapy for VTE?. ### Response: net health benefit.


Instruction: Some panel members were concerned about thepossibility of VTE following what?

Output: idarucizumab administration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some panel members were concerned about thepossibility of VTE following what?. ### Response: idarucizumab administration.


Instruction: The cost likely outweighs the potential benefit from using what drug?

Output: Idarucizumab

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The cost likely outweighs the potential benefit from using what drug?. ### Response: Idarucizumab.


Instruction: What does the cost of idarucizumab likely outweigh the potential benefit of?

Output: non –life-threatening bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the cost of idarucizumab likely outweigh the potential benefit of?. ### Response: non –life-threatening bleeding.


Instruction: What variables define the need for intervention with overholding dabigatran alone?

Output: death, worsening and/orrecurrence of bleeding, and thromboembolic complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What variables define the need for intervention with overholding dabigatran alone?. ### Response: death, worsening and/orrecurrence of bleeding, and thromboembolic complications.


Instruction: What should not be used in patients with HF or LV systolic dysfunc-tion?

Output: Diltiazem or verapamil

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be used in patients with HF or LV systolic dysfunc-tion?. ### Response: Diltiazem or verapamil.


Instruction: What should be avoided because of its short-acting effect?

Output: nifedipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be avoided because of its short-acting effect?. ### Response: nifedipine.


Instruction: What should be avoided because it causes reflex sympathetic activation and worsening myocardial ischemia?

Output: short-acting nifedipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be avoided because it causes reflex sympathetic activation and worsening myocardial ischemia?. ### Response: short-acting nifedipine.


Instruction: What is useful in the management of hypertension in patients with stable angina?

Output: CCBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful in the management of hypertension in patients with stable angina?. ### Response: CCBs.


Instruction: There is no consensus about what role CCBs play in preventing cardiovascular events?

Output: their role in preventing cardiovascular events in patients with established CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no consensus about what role CCBs play in preventing cardiovascular events?. ### Response: their role in preventing cardiovascular events in patients with established CAD.


Instruction: How many hypertensive patients with chronic CAD were randomized to the non-dihydropyridine CCB verapamil or the -blocker atenolol?

Output: >22 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hypertensive patients with chronic CAD were randomized to the non-dihydropyridine CCB verapamil or the -blocker atenolol?. ### Response: >22 000.


Instruction: What was the ACE inhibitor trandolapril added to by 24 months?

Output: 63% of verapamil patients and 52% of atenolol patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the ACE inhibitor trandolapril added to by 24 months?. ### Response: 63% of verapamil patients and 52% of atenolol patients.


Instruction: What was added to 44% of verapamil patients?

Output: hydrochlorothiazide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was added to 44% of verapamil patients?. ### Response: hydrochlorothiazide.


Instruction: What percentage of atenolol patients were treated with hydrochlorothiazide?

Output: 60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of atenolol patients were treated with hydrochlorothiazide?. ### Response: 60%.


Instruction: How long did the follow-up of the study last?

Output: 4.2 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the follow-up of the study last?. ### Response: 4.2 years.


Instruction: How long was the mean follow-up of ALLHAT patients?

Output: 2.7 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the mean follow-up of ALLHAT patients?. ### Response: 2.7 years.


Instruction: What percentage of patients had a history or signs of atherosclerotic vascular disease?

Output: More than 50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients had a history or signs of atherosclerotic vascular disease?. ### Response: More than 50%.


Instruction: There was no significant difference in the inci-dence of coronary end points among patients allocated what?

Output: a thiazide-type diuretic, a long-acting dihydropyridine CCB, or an ACE inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There was no significant difference in the inci-dence of coronary end points among patients allocated what?. ### Response: a thiazide-type diuretic, a long-acting dihydropyridine CCB, or an ACE inhibitor.


Instruction: What is a diuretic?

Output: thiazide-type

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a diuretic?. ### Response: thiazide-type.


Instruction: What is an ACE inhibitor?

Output: trandolapril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ACE inhibitor?. ### Response: trandolapril.


Instruction: Who compared amlodipine or enalapril with placebo?

Output: CAMELOT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who compared amlodipine or enalapril with placebo?. ### Response: CAMELOT.


Instruction: How much of the normotensive patients with CAD had a history of hypertension?

Output: ≈60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the normotensive patients with CAD had a history of hypertension?. ### Response: ≈60%.


Instruction: What group had less adverse cardiovascular events than the enalapril group?

Output: amlodipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group had less adverse cardiovascular events than the enalapril group?. ### Response: amlodipine.


Instruction: What was the result of an intravascu-lar ultrasound substudy of CAMELOT?

Output: progression of atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the result of an intravascu-lar ultrasound substudy of CAMELOT?. ### Response: progression of atherosclerosis.


Instruction: In what group did a trend toward progression occur in atherosclerosis?

Output: enalapril group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what group did a trend toward progression occur in atherosclerosis?. ### Response: enalapril group.


Instruction: What group had no progression in the amlodipine group?

Output: placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group had no progression in the amlodipine group?. ### Response: placebo.


Instruction: What may have pleiotropic effects beyond BP lowering that favor atherosclerotic plaque stabilization?

Output: Amlodipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have pleiotropic effects beyond BP lowering that favor atherosclerotic plaque stabilization?. ### Response: Amlodipine.


Instruction: How many hypertensive patients at high risk of cardiac events were randomized to valsartan?

Output: 15 245

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many hypertensive patients at high risk of cardiac events were randomized to valsartan?. ### Response: 15 245.


Instruction: Forty-six percent of patients in both groups had what?

Output: CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Forty-six percent of patients in both groups had what?. ### Response: CAD.


Instruction: What percentage of patients in both groups had CAD?

Output: Forty-six percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients in both groups had CAD?. ### Response: Forty-six percent.


Instruction: How long was the mean follow-up?

Output: 4.2 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the mean follow-up?. ### Response: 4.2 years.


Instruction: What was the primary composite end point of cardiac mor-bidity and mortality?

Output: thiazide-type diuretic, a long-acting dihydropyridine CCB, or an ACE inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary composite end point of cardiac mor-bidity and mortality?. ### Response: thiazide-type diuretic, a long-acting dihydropyridine CCB, or an ACE inhibitor.


Instruction: In which group was the risk of MI lower?

Output: amlodip-ine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In which group was the risk of MI lower?. ### Response: amlodip-ine.


Instruction: What was lower in the valsartan group?

Output: the risk of new-onset diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was lower in the valsartan group?. ### Response: the risk of new-onset diabetes mellitus.


Instruction: What drug was signifi-cative for diabetes mellitus?

Output: valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was signifi-cative for diabetes mellitus?. ### Response: valsartan.


Instruction: What is performed after PCI?

Output: while the patient is receiving DAPT).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed after PCI?. ### Response: while the patient is receiving DAPT)..


Instruction: What may be associated with lower graft patency rates compared with CABG performedthrough a midline sternotomy?

Output: minimally invasive CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be associated with lower graft patency rates compared with CABG performedthrough a midline sternotomy?. ### Response: minimally invasive CABG.


Instruction: How many RCTs have been published to date involving hybrid coronary revascularization?

Output: no

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs have been published to date involving hybrid coronary revascularization?. ### Response: no.


Instruction: How long have retrospective series of hybrid re-vascularization reported low mor-tality rates?

Output: 10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long have retrospective series of hybrid re-vascularization reported low mor-tality rates?. ### Response: 10 years.


Instruction: What are event-free survival rates at 6-12 months?

Output: 83% to92%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are event-free survival rates at 6-12 months?. ### Response: 83% to92%.


Instruction: What is the survival rate of a PCI procedure at 6 to 12 months of follow-up?

Output: 83% to92%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the survival rate of a PCI procedure at 6 to 12 months of follow-up?. ### Response: 83% to92%.


Instruction: How long does it take for a hybrid coronary revascularization to have a similar outcome?

Output: 30 days and6 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a hybrid coronary revascularization to have a similar outcome?. ### Response: 30 days and6 months.


Instruction: What are the three components that define a successful PCI?

Output: angiographic findings, proceduralevents, and clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the three components that define a successful PCI?. ### Response: angiographic findings, proceduralevents, and clinical outcomes.


Instruction: What are the three components of a PCI procedure?

Output: angiographic findings, proceduralevents, and clinical outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the three components of a PCI procedure?. ### Response: angiographic findings, proceduralevents, and clinical outcomes.


Instruction: What does a successful PCI produce to improve coronary artery bloodflow?

Output: sufficient enlargement of thelumen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a successful PCI produce to improve coronary artery bloodflow?. ### Response: sufficient enlargement of thelumen.


Instruction: How is a balloon angioplasty defined?

Output: thereduction of a minimum stenosis diameter to /H1102150% with afinal TIMI flow grade 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is a balloon angioplasty defined?. ### Response: thereduction of a minimum stenosis diameter to /H1102150% with afinal TIMI flow grade 3.


Instruction: What is the minimum stenosis diameter for coronary stents?

Output: /H1102110%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the minimum stenosis diameter for coronary stents?. ### Response: /H1102110%.


Instruction: What has previously been the clinical benchmark of an optimal angio-graphic result?

Output: a minimum stenosisdiameter of /H1102120%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has previously been the clinical benchmark of an optimal angio-graphic result?. ### Response: a minimum stenosisdiameter of /H1102120%.


Instruction: What was the clinical benchmark of an optimal angio-graphic result?

Output: Procedural Success

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the clinical benchmark of an optimal angio-graphic result?. ### Response: Procedural Success.


Instruction: What did the writing committee conclude about a minimum diameter stenosis?

Output: should be thenew benchmark for lesions treated with coronary stenting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing committee conclude about a minimum diameter stenosis?. ### Response: should be thenew benchmark for lesions treated with coronary stenting.


Instruction: What should be the new benchmark for lesions treated with coronary stenting?

Output: a minimum diameter stenosis of /H1102110%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the new benchmark for lesions treated with coronary stenting?. ### Response: a minimum diameter stenosis of /H1102110%.


Instruction: What should there be final TIMI flowgrade 3 without?

Output: occlusion of a significant side branch,flow-limiting dissection, distal embolization, or angiographicthrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should there be final TIMI flowgrade 3 without?. ### Response: occlusion of a significant side branch,flow-limiting dissection, distal embolization, or angiographicthrombus.


Instruction: What are some of the problems with determining angiographic success?

Output: disparities between the visual assessment andcomputer-aided quantitative stenosis measurement and self-reporting of success in clinical reports or databases

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the problems with determining angiographic success?. ### Response: disparities between the visual assessment andcomputer-aided quantitative stenosis measurement and self-reporting of success in clinical reports or databases.


Instruction: What is a problem with the visual assessment and computer-aided quantitative stenosis measurement?

Output: disparities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a problem with the visual assessment and computer-aided quantitative stenosis measurement?. ### Response: disparities.


Instruction: How should a successful PCI achieve success with-out associated in-hospital complications?

Output: Procedural Success

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should a successful PCI achieve success with-out associated in-hospital complications?. ### Response: Procedural Success.


Instruction: What are major clinical complications?

Output: death, MI, stroke, emergency CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are major clinical complications?. ### Response: death, MI, stroke, emergency CABG.


Instruction: What are discussed in Sections 3.3 and 5.10.3.1.3?

Output: Issues regarding thediagnosis and prognostic implications of procedure-relatedMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are discussed in Sections 3.3 and 5.10.3.1.3?. ### Response: Issues regarding thediagnosis and prognostic implications of procedure-relatedMI.


Instruction: A clinically successful PCI requires both anatomic and procedural success along with what?

Output: relief of signsand/or symptoms of myocardial ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A clinically successful PCI requires both anatomic and procedural success along with what?. ### Response: relief of signsand/or symptoms of myocardial ischemia.


Instruction: What are signs and symptoms of myocardial ischemia?

Output: relief

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are signs and symptoms of myocardial ischemia?. ### Response: relief.


Instruction: Long-term clinicalsuccess requires that what remain?

Output: short-term clinical success

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Long-term clinicalsuccess requires that what remain?. ### Response: short-term clinical success.


Instruction: How is StrokeStroke available at www.ahajournals.org/journal/strAHA/ASA GUIDELINE?

Output: e364

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is StrokeStroke available at www.ahajournals.org/journal/strAHA/ASA GUIDELINE?. ### Response: e364.


Instruction: What is the name of the guideline for the prevention of stroke in patients with stroke and transient ischemic attack?

Output: e364Stroke is available at www.ahajournals.org/journal/strAHA/ASA GUIDELINE2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for the prevention of stroke in patients with stroke and transient ischemic attack?. ### Response: e364Stroke is available at www.ahajournals.org/journal/strAHA/ASA GUIDELINE2021.


Instruction: The American Association of Neurological Surgeons is endorsed by which organization?

Output: American Academy of Neurology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The American Association of Neurological Surgeons is endorsed by which organization?. ### Response: American Academy of Neurology.


Instruction: The Society of Vascular and Interventional Neurology endorses this statement as what?

Output: an educational tool for neurologists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Society of Vascular and Interventional Neurology endorses this statement as what?. ### Response: an educational tool for neurologists.


Instruction: Amytis Towfighi is an MD, FAHA, what position?

Output: Vice Chair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Amytis Towfighi is an MD, FAHA, what position?. ### Response: Vice Chair.


Instruction: Who endorses the statement as educational tool for neurologists?

Output: The American Academy of Neurology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who endorses the statement as educational tool for neurologists?. ### Response: The American Academy of Neurology.


Instruction: What is Amytis Towfighi's position?

Output: Vice Chair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Amytis Towfighi's position?. ### Response: Vice Chair.


Instruction: What is Seemant Chaturvedi's job title?

Output: MD, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Seemant Chaturvedi's job title?. ### Response: MD, FAHA.


Instruction: What is the title of Enrique C. Leira's doctorate in FAHA?

Output: MD, MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of Enrique C. Leira's doctorate in FAHA?. ### Response: MD, MS.


Instruction: Who is the doctorate of Olive Lennon's?

Output: PhD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the doctorate of Olive Lennon's?. ### Response: PhD.


Instruction: What doctorate is Thanh N. Nguyen's graduate?

Output: FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What doctorate is Thanh N. Nguyen's graduate?. ### Response: FAHA.


Instruction: Which doctorates is Anjail Z. Sharrief?

Output: MD, MPH, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which doctorates is Anjail Z. Sharrief?. ### Response: MD, MPH, FAHA.


Instruction: What is Tanya N. Turan's profession?

Output: MD, MS, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Tanya N. Turan's profession?. ### Response: MD, MS, FAHA.


Instruction: What is Linda S. Williams' specialty?

Output: MD, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Linda S. Williams' specialty?. ### Response: MD, FAHA.


Instruction: How do specific recommendations for prevention strategies often depend on?

Output: ischemic stroke/tran-sient ischemic attack subtype

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How do specific recommendations for prevention strategies often depend on?. ### Response: ischemic stroke/tran-sient ischemic attack subtype.


Instruction: What often depend on the ischemic stroke/tran-sient ischemia attack subtype?

Output: Specific recommendations for prevention strate-gies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What often depend on the ischemic stroke/tran-sient ischemia attack subtype?. ### Response: Specific recommendations for prevention strate-gies.


Instruction: What section describes recommen-dations for the diagnostic workup after ischmic stroke?

Output: Guideline for the Prevention of Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section describes recommen-dations for the diagnostic workup after ischmic stroke?. ### Response: Guideline for the Prevention of Stroke.


Instruction: What are the recommendations now grouped by?

Output: etiologic subtype

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations now grouped by?. ### Response: etiologic subtype.


Instruction: What remains extremely important in secondary stroke preven-tion?

Output: Management of vascular risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains extremely important in secondary stroke preven-tion?. ### Response: Management of vascular risk factors.


Instruction: What type of medical management is usually best?

Output: Intensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of medical management is usually best?. ### Response: Intensive.


Instruction: What are goals of therapy tailored to?

Output: the individual patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are goals of therapy tailored to?. ### Response: the individual patient.


Instruction: Lifestyle factors, including healthy diet and physical activity, are important for preventing what?

Output: a second stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Lifestyle factors, including healthy diet and physical activity, are important for preventing what?. ### Response: a second stroke.