Instruction: Who was followed up from 1991 to 1992 until 2004.219?

Output: 49 259 Swedish women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was followed up from 1991 to 1992 until 2004.219?. ### Response: 49 259 Swedish women.


Instruction: In the 285 cases of incident stroke that included ischemic, hemorrhagic, and unknown types, there was no significant association between what?

Output: OC use, duration, or type of OC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the 285 cases of incident stroke that included ischemic, hemorrhagic, and unknown types, there was no significant association between what?. ### Response: OC use, duration, or type of OC.


Instruction: What was not associated with stroke after adjustment for cigarette smoking, hypertension, diabetes mellitus, alcohol, BMI, education, and physical activity?

Output: Reproductive factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not associated with stroke after adjustment for cigarette smoking, hypertension, diabetes mellitus, alcohol, BMI, education, and physical activity?. ### Response: Reproductive factors.


Instruction: What did the second study estimate rates of?

Output: IS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the second study estimate rates of?. ### Response: IS.


Instruction: What did the second study estimate rates of in women aged 15 to 49 years?

Output: IS only

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the second study estimate rates of in women aged 15 to 49 years?. ### Response: IS only.


Instruction: What were the RRs associated with use of various doses and formulations of hormonal contracep-tion in Denmark?

Output: 144

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the RRs associated with use of various doses and formulations of hormonal contracep-tion in Denmark?. ### Response: 144.


Instruction: How many women were in the population-based cohort of 1.6 million?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many women were in the population-based cohort of 1.6 million?. ### Response: ≈.


Instruction: How many women were in Denmark?

Output: ≈1.6 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many women were in Denmark?. ### Response: ≈1.6 million.


Instruction: What was the crude incidence of IS in contraceptive users?

Output: 21.4 per 100 000 person-years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the crude incidence of IS in contraceptive users?. ### Response: 21.4 per 100 000 person-years.


Instruction: The adjusted RR for ethinyl estradiol doses was what?

Output: 1.40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The adjusted RR for ethinyl estradiol doses was what?. ### Response: 1.40.


Instruction: What was the RR for the 20-g dose?

Output: 0.88 (0.22–3.53) to 1.53

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR for the 20-g dose?. ### Response: 0.88 (0.22–3.53) to 1.53.


Instruction: What was not associated with progestin-only formulations?

Output: Reproductive factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not associated with progestin-only formulations?. ### Response: Reproductive factors.


Instruction: What is the difference between mechanical and bioprosthetic valves?

Output: very durable but require lifelong anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between mechanical and bioprosthetic valves?. ### Response: very durable but require lifelong anticoagulation.


Instruction: What are the approximate ages based on?

Output: US Actuarial Life Expectancy tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the approximate ages based on?. ### Response: US Actuarial Life Expectancy tables.


Instruction: The balance between expected patient longevity and valve durability fluctuates across what age range?

Output: continuously across the age range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The balance between expected patient longevity and valve durability fluctuates across what age range?. ### Response: continuously across the age range.


Instruction: What are more durable valves preferred for patients with a longer life expectancy?

Output: TAVI versus SAVR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are more durable valves preferred for patients with a longer life expectancy?. ### Response: TAVI versus SAVR.


Instruction: What is finite (with shorter durability for younger patients)?

Output: Bioprosthetic valve durability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is finite (with shorter durability for younger patients)?. ### Response: Bioprosthetic valve durability.


Instruction: Mechanical valves are very durable but require what?

Output: lifelong anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Mechanical valves are very durable but require what?. ### Response: lifelong anticoagulation.


Instruction: Long-term data on outcomes with surgical bioprosthetic valves is available; what is robust data on?

Output: transcatheter bioprosthetic valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Long-term data on outcomes with surgical bioprosthetic valves is available; what is robust data on?. ### Response: transcatheter bioprosthetic valves.


Instruction: How long does robust data on transcatheter bioprosthetic valves last?

Output: 5 y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does robust data on transcatheter bioprosthetic valves last?. ### Response: 5 y.


Instruction: What should be individualized on the basis of patient-specific factors?

Output: The deci-sion about valve type

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be individualized on the basis of patient-specific factors?. ### Response: The deci-sion about valve type.


Instruction: What is the difference between TAVI and SAVR?

Output: Bioprosthetic valve durability is finite

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between TAVI and SAVR?. ### Response: Bioprosthetic valve durability is finite.


Instruction: What does AVR mean?

Output: aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AVR mean?. ### Response: aortic valve replacement.


Instruction: Where can you download this article?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you download this article?. ### Response: http://ahajournals.org.


Instruction: When was this article published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 28, 2023.


Instruction: What did Julius S, Nesbitt SD, Egan BM, et al. treat with an angiotensin-receptor blocker?

Output: pre-hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Julius S, Nesbitt SD, Egan BM, et al. treat with an angiotensin-receptor blocker?. ### Response: pre-hypertension.


Instruction: When did N Engl J Med. 2006:354:1685-97?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med. 2006:354:1685-97?. ### Response: 2006.


Instruction: What study was based on the Seventh Report of the Joint National Committee on Hypertension definition of hypertension?

Output: TROPHY

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study was based on the Seventh Report of the Joint National Committee on Hypertension definition of hypertension?. ### Response: TROPHY.


Instruction: What did the TROPHY study focus on?

Output: outcomes based on the Seventh Report of the Joint National Committee on Hypertension definition of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the TROPHY study focus on?. ### Response: outcomes based on the Seventh Report of the Joint National Committee on Hypertension definition of hypertension.


Instruction: What is ramipril an angiotensin-converting enzyme inhibitor used for?

Output: pre-vention of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ramipril an angiotensin-converting enzyme inhibitor used for?. ### Response: pre-vention of hypertension.


Instruction: What is the name of the German Hypertension League's randomized, controlled prevention trial?

Output: PHARAO study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the German Hypertension League's randomized, controlled prevention trial?. ### Response: PHARAO study.


Instruction: When was the PHARAO study conducted?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the PHARAO study conducted?. ### Response: 2008.


Instruction: What is chlorthalidone plus amiloride effective for?

Output: prevention of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is chlorthalidone plus amiloride effective for?. ### Response: prevention of hypertension.


Instruction: What is the name of the PREVER Prevention Randomized Clinical Trial?

Output: Effectiveness of chlorthalidone plus amiloride for the prevention of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PREVER Prevention Randomized Clinical Trial?. ### Response: Effectiveness of chlorthalidone plus amiloride for the prevention of hypertension.


Instruction: How is blood pressure lower in intermediate-risk persons without cardiovascular disease?

Output: Blood-pressure lower -ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is blood pressure lower in intermediate-risk persons without cardiovascular disease?. ### Response: Blood-pressure lower -ing.


Instruction: What is the name of the multicenter clinical trial that compares two strategies for control of systolic blood pressure?

Output: Systolic Blood Pressure Intervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter clinical trial that compares two strategies for control of systolic blood pressure?. ### Response: Systolic Blood Pressure Intervention Trial.


Instruction: What is S8.1.3-2?

Output: Systolic Blood Pressure Intervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is S8.1.3-2?. ### Response: Systolic Blood Pressure Intervention Trial.


Instruction: What is Pressure Intervention Trial?

Output: Systolic Blood Pressure Intervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Pressure Intervention Trial?. ### Response: Systolic Blood Pressure Intervention Trial.


Instruction: What is the name of the pressure intervention trial?

Output: Systolic Blood Pressure Intervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pressure intervention trial?. ### Response: Systolic Blood Pressure Intervention Trial.


Instruction: When was the last time a blood pressure intervention was used?

Output: 1967

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a blood pressure intervention was used?. ### Response: 1967.


Instruction: What is the name of the multi-ethnic study of atherosclerosis?

Output: Ethnic differences in hyper -tension incidence among middle-aged and older adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-ethnic study of atherosclerosis?. ### Response: Ethnic differences in hyper -tension incidence among middle-aged and older adults.


Instruction: What are the names of the two drugs used in hypertension?

Output: chlorthalidone plus amiloride

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the two drugs used in hypertension?. ### Response: chlorthalidone plus amiloride.


Instruction: Who is the author of the study?

Output: Figueiredo Neto JA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study?. ### Response: Figueiredo Neto JA.


Instruction: What is the name of the ONTARGET Investigators?

Output: N Engl J Med. 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ONTARGET Investigators?. ### Response: N Engl J Med. 2008.


Instruction: What are the names of the investigators that investigated Telmisartan, ramipril, or both in patients at high risk for vascular events?

Output: Yusuf S, Teo KK, Pogue J, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. ONTARGET Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the investigators that investigated Telmisartan, ramipril, or both in patients at high risk for vascular events?. ### Response: Yusuf S, Teo KK, Pogue J, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. ONTARGET Investigators.


Instruction: When was the N Engl J Med 358:1547-59?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 358:1547-59?. ### Response: 2008.


Instruction: What is the name of the drug used for the treatment of diabetic nephropathy?

Output: Combined angiotensin inhibition

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used for the treatment of diabetic nephropathy?. ### Response: Combined angiotensin inhibition.


Instruction: What are the average diastolic blood pressures in patients with hypertension?

Output: 115 through 129 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the average diastolic blood pressures in patients with hypertension?. ### Response: 115 through 129 mm Hg.


Instruction: What is the average diastolic blood pressure?

Output: 115 through 129 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average diastolic blood pressure?. ### Response: 115 through 129 mm Hg.


Instruction: What are the findings of the hypertension detection and follow-up pro-gram?

Output: Five-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the findings of the hypertension detection and follow-up pro-gram?. ### Response: Five-year.


Instruction: What predicts embolic events after TEE?

Output: An increase in vegetation size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts embolic events after TEE?. ### Response: An increase in vegetation size.


Instruction: What has been observed to occur in a second, but infrequent, peak?

Output: late embolic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been observed to occur in a second, but infrequent, peak?. ### Response: late embolic events.


Instruction: How long does it take to increase vegetation size?

Output: 4 to 8 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to increase vegetation size?. ### Response: 4 to 8 weeks.


Instruction: When does peak of late embolic events occur?

Output: 15 to 30 weeks after the diagnosis of IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When does peak of late embolic events occur?. ### Response: 15 to 30 weeks after the diagnosis of IE.


Instruction: What is nonhealing veg-etations?

Output: failure of a vegetation to stabilize or diminish in size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is nonhealing veg-etations?. ### Response: failure of a vegetation to stabilize or diminish in size.


Instruction: What is the traditional indication for valvular surgery for IE to avoid embolization?

Output: ≥2 major embolic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the traditional indication for valvular surgery for IE to avoid embolization?. ### Response: ≥2 major embolic events.


Instruction: What is common among IE patients who develop embolic events?

Output: embolism occurring before the insti-tution of therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is common among IE patients who develop embolic events?. ### Response: embolism occurring before the insti-tution of therapy.


Instruction: What is the benefit of surgery in avoiding catastrophic embolic events greatest early in the treatment course of IE?

Output: Because of the observed decreases in embolic risk during the first 2 weeks of antibiotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of surgery in avoiding catastrophic embolic events greatest early in the treatment course of IE?. ### Response: Because of the observed decreases in embolic risk during the first 2 weeks of antibiotic therapy.


Instruction: Early surgi-cal intervention may preclude a primary or recurrent what?

Output: major embolic event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Early surgi-cal intervention may preclude a primary or recurrent what?. ### Response: major embolic event.


Instruction: What may prevent a primary or recurrent major embolic event but exposes the patient to both immediate and lifelong risks of valve replacement if the valve cannot be pri-marily repaired?

Output: Early surgi-cal intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may prevent a primary or recurrent major embolic event but exposes the patient to both immediate and lifelong risks of valve replacement if the valve cannot be pri-marily repaired?. ### Response: Early surgi-cal intervention.


Instruction: What is the strategy for surgical inter vention to avoid systemic embolization in IE?

Output: specific

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strategy for surgical inter vention to avoid systemic embolization in IE?. ### Response: specific.


Instruction: To avoid systemic embolization in IE remains specific What is the name of the website that will be used to download the ahajournals.org?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To avoid systemic embolization in IE remains specific What is the name of the website that will be used to download the ahajournals.org?. ### Response: http://ahajournals.org.


Instruction: On what date will it be available for download?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date will it be available for download?. ### Response: April 28, 2023.


Instruction: What drug did not treat patients with high-level aminoglycoside-resistant strains?

Output: ampicillin-gentamicin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug did not treat patients with high-level aminoglycoside-resistant strains?. ### Response: ampicillin-gentamicin.


Instruction: What were the limitations of both of these studies?

Output: They were observational, largely retrospective, and nonran-domized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the limitations of both of these studies?. ### Response: They were observational, largely retrospective, and nonran-domized.


Instruction: How were the regimens not standardized among the dif-ferent?

Output: They were observational, largely retrospective, and nonran-domized; the regimens were not standardized among the dif-ferent centers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were the regimens not standardized among the dif-ferent?. ### Response: They were observational, largely retrospective, and nonran-domized; the regimens were not standardized among the dif-ferent centers.


Instruction: What was not standardized among the dif-ferent centers?

Output: the regimens

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not standardized among the dif-ferent centers?. ### Response: the regimens.


Instruction: What was at the discretion of the investigators and not always the result of gentamicin-associated nephrotoxicity?

Output: discontinuation of gentamicin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was at the discretion of the investigators and not always the result of gentamicin-associated nephrotoxicity?. ### Response: discontinuation of gentamicin therapy.


Instruction: What is the name of the study that was downloaded from http://ahajournals.org by on April 28, 2023?

Output: ceftriaxone-ampicillin therapy of aminogly-coside-susceptible with high-level aminoglycoside-resistant E faecalis IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that was downloaded from http://ahajournals.org by on April 28, 2023?. ### Response: ceftriaxone-ampicillin therapy of aminogly-coside-susceptible with high-level aminoglycoside-resistant E faecalis IE.


Instruction: What is FSGC?

Output: Formosa Stroke Genetic Consortium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is FSGC?. ### Response: Formosa Stroke Genetic Consortium.


Instruction: What is the association between genetic variant on chromosome 12p13 and stroke survival and recurrence?

Output: Formosa Stroke Genetic Consortium (FSGC). Association between genetic variant on chromosome 12p13 and stroke survival and recur -rence: a one year prospective study in Taiwan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between genetic variant on chromosome 12p13 and stroke survival and recurrence?. ### Response: Formosa Stroke Genetic Consortium (FSGC). Association between genetic variant on chromosome 12p13 and stroke survival and recur -rence: a one year prospective study in Taiwan.


Instruction: What chromosome is involved in stroke survival?

Output: 12p13

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What chromosome is involved in stroke survival?. ### Response: 12p13.


Instruction: What is the name of the prospective study?

Output: Formosa Stroke Genetic Consortium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study?. ### Response: Formosa Stroke Genetic Consortium.


Instruction: Where was the study conducted?

Output: Taiwan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the study conducted?. ### Response: Taiwan.


Instruction: How long did the study last?

Output: one year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the study last?. ### Response: one year.


Instruction: What is MW?

Output: Parsons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MW?. ### Response: Parsons.


Instruction: What is Lewis MD?

Output: Lincz LF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Lewis MD?. ### Response: Lincz LF.


Instruction: Where is Peel R?

Output: Oldmeadow C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Peel R?. ### Response: Oldmeadow C.


Instruction: Who is Moscato P?

Output: Smith W

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Moscato P?. ### Response: Smith W.


Instruction: What is the name of the person who wrote this article?

Output: Hsieh YC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who wrote this article?. ### Response: Hsieh YC.


Instruction: When was this article published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 28, 2023.


Instruction: Where was it downloaded?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was it downloaded?. ### Response: http://ahajournals.org.


Instruction: Who wrote the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the name of the content reviewer?

Output: Jacqueline E. Tamis-Holland

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the content reviewer?. ### Response: Jacqueline E. Tamis-Holland.


Instruction: Who is the Content Reviewer—Joint Committee on Clinical Practice Guidelines?

Output: Bulent Gorenek

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Content Reviewer—Joint Committee on Clinical Practice Guidelines?. ### Response: Bulent Gorenek.


Instruction: Who is a content reviewer at ACC/AHA Mayo Clinic?

Output: Carole A. Warnes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a content reviewer at ACC/AHA Mayo Clinic?. ### Response: Carole A. Warnes.


Instruction: What is the name of the committee that reviews content at the Mayo clinic?

Output: Jacqueline E. Tamis-Holland

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that reviews content at the Mayo clinic?. ### Response: Jacqueline E. Tamis-Holland.


Instruction: Who is a content reviewer at ACC/AHA?

Output: David E. Newby

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a content reviewer at ACC/AHA?. ### Response: David E. Newby.


Instruction: What is the name of the person who reviewed content for ACC and AHA at Northwestern Hospital?

Output: David H. Adams

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who reviewed content for ACC and AHA at Northwestern Hospital?. ### Response: David H. Adams.


Instruction: Who is a content reviewer for the Joint Committee on Clinical Practice Guidelines?

Output: Jacqueline E. Tamis-Holland

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a content reviewer for the Joint Committee on Clinical Practice Guidelines?. ### Response: Jacqueline E. Tamis-Holland.


Instruction: What is the name of the professor of medicine at Duke Clinical Research Institute?

Output: Daniel B. Mark

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at Duke Clinical Research Institute?. ### Response: Daniel B. Mark.


Instruction: Who is a Content Reviewer for the Joint Committee on Clinical Practice Guidelines?

Output: Jacqueline E. Tamis-Holland

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Content Reviewer for the Joint Committee on Clinical Practice Guidelines?. ### Response: Jacqueline E. Tamis-Holland.


Instruction: What is the name of the organization that reviews clinical practice guidelines at Virginia Commonwealth University?

Output: School of Pharmacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that reviews clinical practice guidelines at Virginia Commonwealth University?. ### Response: School of Pharmacy.


Instruction: Who is a Content Reviewer at ACC/AHA Mt. Sinai Medical Center?

Output: David H. Adams

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Content Reviewer at ACC/AHA Mt. Sinai Medical Center?. ### Response: David H. Adams.


Instruction: What is the title of the Newby Content Reviewer at the University of Edinburgh?

Output: Professor of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the Newby Content Reviewer at the University of Edinburgh?. ### Response: Professor of Cardiology.


Instruction: Who is the Professor of Cardiology at the Chancellor’s Building?

Output: AstraZeneca

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Professor of Cardiology at the Chancellor’s Building?. ### Response: AstraZeneca.


Instruction: Which company is affiliated with AstraZeneca?

Output: Bristol-Myers Squ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which company is affiliated with AstraZeneca?. ### Response: Bristol-Myers Squ.


Instruction: What company is associated with CellProthera?

Output: Bristol-Myers Squibb Company

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What company is associated with CellProthera?. ### Response: Bristol-Myers Squibb Company.


Instruction: What is a DSMB?

Output: UCB Inc

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a DSMB?. ### Response: UCB Inc.


Instruction: Who is the Content Reviewer?

Output: Brian R. Lindman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Content Reviewer?. ### Response: Brian R. Lindman.


Instruction: What is the name of the committee that reviews clinical practice guidelines?

Output: Joint Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the committee that reviews clinical practice guidelines?. ### Response: Joint Committee.


Instruction: What is the name of the group that reviewed the guidelines?

Output: Joint Committee on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that reviewed the guidelines?. ### Response: Joint Committee on Clinical Practice Guidelines.


Instruction: What is NIH's affiliation with the NGS Predict Study?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NIH's affiliation with the NGS Predict Study?. ### Response: None.


Instruction: What is the name of the NGS Predict Study?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the NGS Predict Study?. ### Response: None.


Instruction: What is another name for the NIH?

Output: The NGS Predict Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the NIH?. ### Response: The NGS Predict Study.


Instruction: What is the name of the journal that was downloaded from http://ahajournals.org on April 28, 2023?

Output: ahajournals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that was downloaded from http://ahajournals.org on April 28, 2023?. ### Response: ahajournals.


Instruction: What does MRI brain imaging phenotypes and mapping genes associated with varia-tion in these traits do?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does MRI brain imaging phenotypes and mapping genes associated with varia-tion in these traits do?. ### Response: )*.


Instruction: What is Regeneron discussing joint research involving exome sequencing of ischemic strokes in young adults internationally?

Output: no personal research support at present

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Regeneron discussing joint research involving exome sequencing of ischemic strokes in young adults internationally?. ### Response: no personal research support at present.


Instruction: When were the disclosures downloaded from http://ahajournals.org?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were the disclosures downloaded from http://ahajournals.org?. ### Response: April 28, 2023.


Instruction: What was the relative risk of death from CV disease reduced by 18%?

Output: HR: 0.82; 95% CI: 0.68 –0.98

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the relative risk of death from CV disease reduced by 18%?. ### Response: HR: 0.82; 95% CI: 0.68 –0.98.


Instruction: What was reduced by 14%?

Output: deathfrom any cause

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was reduced by 14%?. ### Response: deathfrom any cause.


Instruction: What was the BP of patients with CKD G1 or G2?

Output: SBP 5.3/DBP 2.1 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the BP of patients with CKD G1 or G2?. ### Response: SBP 5.3/DBP 2.1 mm Hg.


Instruction: What was SBP 4.5/DBP 1.8 mm Hg in patientswith CKd G3 –G5?

Output: fall in BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was SBP 4.5/DBP 1.8 mm Hg in patientswith CKd G3 –G5?. ### Response: fall in BP.


Instruction: What percentage of the placebo group were already treated with RASi at baseline?

Output: 49%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the placebo group were already treated with RASi at baseline?. ### Response: 49%.


Instruction: What percentage were on diuretics at baseline in the ADVANCE study?

Output: 25%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage were on diuretics at baseline in the ADVANCE study?. ### Response: 25%.


Instruction: What did diuretics decrease to in the placebo group at the final visit?

Output: 21%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did diuretics decrease to in the placebo group at the final visit?. ### Response: 21%.


Instruction: What may have been due to the addition of the diuretic and/or greater BP lowering?

Output: ﬁts seen in ADVANCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have been due to the addition of the diuretic and/or greater BP lowering?. ### Response: ﬁts seen in ADVANCE.


Instruction: What is emerging evidence that MRA have bene ficial effects on?

Output: clinical kidney outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is emerging evidence that MRA have bene ficial effects on?. ### Response: clinical kidney outcomes.


Instruction: How many participants participated in the FIDELIO-DKD study?

Output: 5734

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants participated in the FIDELIO-DKD study?. ### Response: 5734.


Instruction: What reduced the risk of composite primary endpoint of GFR decline?

Output: ﬁnerenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduced the risk of composite primary endpoint of GFR decline?. ### Response: ﬁnerenone.


Instruction: What reduced the risk of CV events?

Output: Finerenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What reduced the risk of CV events?. ### Response: Finerenone.


Instruction: What was the effect offinerenone on SBPlowering modest?

Output: 2 –3 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect offinerenone on SBPlowering modest?. ### Response: 2 –3 mm Hg.


Instruction: Why was there a higher risk of hyperkalemia-related events in the study?

Output: its effect on SBPlowering was modest (2 –3 mm Hg),

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there a higher risk of hyperkalemia-related events in the study?. ### Response: its effect on SBPlowering was modest (2 –3 mm Hg),.


Instruction: What is a hyperkalemia-related event?

Output: SBPlowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a hyperkalemia-related event?. ### Response: SBPlowering.


Instruction: What drug has not been approved for clinical use at the time of writing of this guideline?

Output: ﬁnerenone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug has not been approved for clinical use at the time of writing of this guideline?. ### Response: ﬁnerenone.


Instruction: When was the trial offinerenone published?

Output: after the evidence review cut-off for the guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the trial offinerenone published?. ### Response: after the evidence review cut-off for the guideline.


Instruction: What was the overall quality of the review on antihypertensive therapies in patients with diabetes and CKD, A2 and A3.259?

Output: moderate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall quality of the review on antihypertensive therapies in patients with diabetes and CKD, A2 and A3.259?. ### Response: moderate.


Instruction: What were the studies examining the use of RASi therapy exhibiting?

Output: study limitations with unclearallocation concealment for critical and important outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the studies examining the use of RASi therapy exhibiting?. ### Response: study limitations with unclearallocation concealment for critical and important outcomes.


Instruction: Why was the quality of the evidence for CV outcomes lower?

Output: there being fewer events and inconsistent reportingof these outcomes in trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the quality of the evidence for CV outcomes lower?. ### Response: there being fewer events and inconsistent reportingof these outcomes in trials.


Instruction: Why was there fewer events and inconsistent reporting of CV outcomes in trials?

Output: The quality of the evidence was lower for CV outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there fewer events and inconsistent reporting of CV outcomes in trials?. ### Response: The quality of the evidence was lower for CV outcomes.


Instruction: What study of patients with CKD G1 – G3, A2 had a low quality of evidence?

Output: ADVANCE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study of patients with CKD G1 – G3, A2 had a low quality of evidence?. ### Response: ADVANCE.


Instruction: Why was the quality of the evidence downgraded?

Output: serious risk ofbias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the quality of the evidence downgraded?. ### Response: serious risk ofbias.


Instruction: Why was there a serious risk ofbias?

Output: unclear allocation concealment, and imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was there a serious risk ofbias?. ### Response: unclear allocation concealment, and imprecision.


Instruction: What was seen only in the CKDsubgroups when the results were negative in the entire cohort?

Output: diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was seen only in the CKDsubgroups when the results were negative in the entire cohort?. ### Response: diuretics.


Instruction: What is the best evidence for renoprotective effects of RASi therapy in patients with diabetes?

Output: CKDG3–G4, and severely increased albuminuria comes from theIDNT162with its active comparator arm, and from theRENAAL200trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the best evidence for renoprotective effects of RASi therapy in patients with diabetes?. ### Response: CKDG3–G4, and severely increased albuminuria comes from theIDNT162with its active comparator arm, and from theRENAAL200trial.


Instruction: What does the IDNT162 have in its active comparator arm?

Output: best evidence for renoprotective effects of RASi therapyindependent of BP control in patients with diabetes, CKDG3–G4, and severely increased albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the IDNT162 have in its active comparator arm?. ### Response: best evidence for renoprotective effects of RASi therapyindependent of BP control in patients with diabetes, CKDG3–G4, and severely increased albuminuria.


Instruction: The Micro-HOPE studyprovides thebest evidence for patients with moderately increased what?

Output: albuminuria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Micro-HOPE studyprovides thebest evidence for patients with moderately increased what?. ### Response: albuminuria.


Instruction: What does aldosterone antagonist do?

Output: medical therapies benefit patients with failing Fontan physiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does aldosterone antagonist do?. ### Response: medical therapies benefit patients with failing Fontan physiology.


Instruction: Who will benefit from ventricular assist devices?

Output: asymptomatic patients with ACHD with PAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who will benefit from ventricular assist devices?. ### Response: asymptomatic patients with ACHD with PAH.


Instruction: What should be the threshold for aortic aneurysm surgery?

Output: ventricular assist devices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the threshold for aortic aneurysm surgery?. ### Response: ventricular assist devices.


Instruction: What is of most benefit?

Output: pacing and resynchronization strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is of most benefit?. ### Response: pacing and resynchronization strategies.


Instruction: What criteria should determine transplantation eligibility?

Output: Outcomes/risk assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria should determine transplantation eligibility?. ### Response: Outcomes/risk assessment.


Instruction: Which patients benefit from primary prevention ICDs?

Output: patients with systemic right ventricles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which patients benefit from primary prevention ICDs?. ### Response: patients with systemic right ventricles.


Instruction: What predicts outcomes in patients with ACHD?

Output: HF risk score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts outcomes in patients with ACHD?. ### Response: HF risk score.


Instruction: What is the rate and/or risk of endocarditis?

Output: Assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rate and/or risk of endocarditis?. ### Response: Assessment.


Instruction: Who is at high risk of neurodevelopmental abnormalities?

Output: Assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is at high risk of neurodevelopmental abnormalities?. ### Response: Assessment.


Instruction: What is the standard protocol for assessing right ventricular size and function by CMR imaging?

Output: biomarkers are predictive of mortality and morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the standard protocol for assessing right ventricular size and function by CMR imaging?. ### Response: biomarkers are predictive of mortality and morbidity.


Instruction: What are predictive of mortality and morbidity?

Output: biomarkers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are predictive of mortality and morbidity?. ### Response: biomarkers.


Instruction: Which biomarkers are predictive of mortality and morbidity?

Output: biomarkers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which biomarkers are predictive of mortality and morbidity?. ### Response: biomarkers.


Instruction: What should be controlled in patients with HFpEF in accordance with published clinical practice guidelines to prevent morbidity?

Output: BSystolic and diastolic blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be controlled in patients with HFpEF in accordance with published clinical practice guidelines to prevent morbidity?. ### Response: BSystolic and diastolic blood pressure.


Instruction: What are clinical practice guidelines to prevent?

Output: morbidity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are clinical practice guidelines to prevent?. ### Response: morbidity.


Instruction: What should be used for relief of symptoms in patients with HFpEF?

Output: CDiuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used for relief of symptoms in patients with HFpEF?. ### Response: CDiuretics.


Instruction: How is CCoronary revascularization reasonable?

Output: in patients with CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is CCoronary revascularization reasonable?. ### Response: in patients with CAD.


Instruction: What is judged to be having an adverse effect on symptomatic HFpEF?

Output: symptoms (angina) or demonstrable myocardial ischemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is judged to be having an adverse effect on symptomatic HFpEF?. ### Response: symptoms (angina) or demonstrable myocardial ischemia.


Instruction: What is management of AF according to published clinical practice guidelines reasonable to improve?

Output: symptomatic HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is management of AF according to published clinical practice guidelines reasonable to improve?. ### Response: symptomatic HF.


Instruction: Which section of the 2013 HF guideline remains current?

Output: Section 9.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which section of the 2013 HF guideline remains current?. ### Response: Section 9.1.


Instruction: What section of the 2013 HF guideline remains current?

Output: Section 9.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section of the 2013 HF guideline remains current?. ### Response: Section 9.1.


Instruction: What is reasonable to control blood pressure in patients with HFpEF?

Output: hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to control blood pressure in patients with HFpEF?. ### Response: hypertension.


Instruction: What color corresponds to COR in Table 1?

Output: Colors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What color corresponds to COR in Table 1?. ### Response: Colors.


Instruction: For all medical therapies, dosing should be optimized and what exercise should be exercised?

Output: serial assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For all medical therapies, dosing should be optimized and what exercise should be exercised?. ### Response: serial assessment.


Instruction: The combination of ISDN/HYD with ARNI has not been robustly tested.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The combination of ISDN/HYD with ARNI has not been robustly tested.. ### Response: †.


Instruction: What should be carefully monitored?

Output: BP response

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be carefully monitored?. ### Response: BP response.


Instruction: What is appropriate for stage C, NYHA class II and III HF?

Output: Participation in investigational studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is appropriate for stage C, NYHA class II and III HF?. ### Response: Participation in investigational studies.


Instruction: What is bpm?

Output: beats per minute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is bpm?. ### Response: beats per minute.


Instruction: What is COR?

Output: Class of Recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is COR?. ### Response: Class of Recommendation.


Instruction: CRT-D is cardiac resynchronization therapy-device; what is GDMT?

Output: guideline-directed management and therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CRT-D is cardiac resynchronization therapy-device; what is GDMT?. ### Response: guideline-directed management and therapy.


Instruction: What is K+?

Output: potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is K+?. ### Response: potassium.


Instruction: What is LBBB?

Output: left bundle-branch block

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is LBBB?. ### Response: left bundle-branch block.


Instruction: Where is NYHA?

Output: New York Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is NYHA?. ### Response: New York Heart Association.


Instruction: When was NYHA released?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was NYHA released?. ### Response: May 3, 2023.


Instruction: How long aft er birth or st ep-do wn does it take to measur e plat elet count, transaminases and serum cr eatinine?

Output: 48–72  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long aft er birth or st ep-do wn does it take to measur e plat elet count, transaminases and serum cr eatinine?. ### Response: 48–72  hours.


Instruction: How long is it normal for transaminases or serum cr eatinine to measure results?

Output: 48–72  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it normal for transaminases or serum cr eatinine to measure results?. ### Response: 48–72  hours.


Instruction: What is the reference range for pre-eclampsia?

Output: 1.5.25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reference range for pre-eclampsia?. ### Response: 1.5.25.


Instruction: How long does it take for results to be normal?

Output: 48–72  hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for results to be normal?. ### Response: 48–72  hours.


Instruction: How long does it take for women with pre-eclampsia to return to normal?

Output: 6–8  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for women with pre-eclampsia to return to normal?. ### Response: 6–8  weeks.


Instruction: Who has giv en bir th, carr y out a urinar y reagent -strip to est 6-8 weeks aft er the Bir th?

Output: women wit h pre-eclampsia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has giv en bir th, carr y out a urinar y reagent -strip to est 6-8 weeks aft er the Bir th?. ### Response: women wit h pre-eclampsia.


Instruction: Who had pr e-eclampsia and still ha ve proteinuria (1+ or more)?

Output: Offer women

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who had pr e-eclampsia and still ha ve proteinuria (1+ or more)?. ### Response: Offer women.


Instruction: How long aft er the bir th does a child go to see their GP or specialist?

Output: 8  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long aft er the bir th does a child go to see their GP or specialist?. ### Response: 8  weeks.


Instruction: How long does it take for the child to see a GP to assess their kidne y function?

Output: 8  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for the child to see a GP to assess their kidne y function?. ### Response: 8  weeks.


Instruction: 1.5.27 Consider r eferring w omen wit h an abnormal kidne y function assessment at how many mont hs?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1.5.27 Consider r eferring w omen wit h an abnormal kidne y function assessment at how many mont hs?. ### Response: 3.


Instruction: What is the NICE guideline on?

Output: chr onic kidne y disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NICE guideline on?. ### Response: chr onic kidne y disease.


Instruction: What is fetal moni toring in chronic h yper tension?

Output: growth

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is fetal moni toring in chronic h yper tension?. ### Response: growth.


Instruction: What is an ultrasound f?

Output: fetal growth and amniotic fluid v olume assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ultrasound f?. ### Response: fetal growth and amniotic fluid v olume assessment.


Instruction: At what age is an umbilical ar tery doppler v elocimetr y?

Output: 28  weeks, 32  weeks and 36  weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At what age is an umbilical ar tery doppler v elocimetr y?. ### Response: 28  weeks, 32  weeks and 36  weeks.


Instruction: What doppler v elocimetr y at 28 weeks, 32 weeks and 36 weeks?

Output: umbilical ar tery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What doppler v elocimetr y at 28 weeks, 32 weeks and 36 weeks?. ### Response: umbilical ar tery.


Instruction: In women with h yper tension, only carr out car diotocograph y if clinically indicated?

Output: 1.6.2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In women with h yper tension, only carr out car diotocograph y if clinically indicated?. ### Response: 1.6.2.


Instruction: When was Hyper tension in pregnancy: diagnosis and management (NG133)?

Output: © NICE 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Hyper tension in pregnancy: diagnosis and management (NG133)?. ### Response: © NICE 2023.


Instruction: When was the last updat ed on 17 April 2023?

Output: Page 26of 59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed on 17 April 2023?. ### Response: Page 26of 59.


Instruction: What is a guideline for the secondary prevention of Ischemic Stroke?

Output: EPIC-CVD case-cohort study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a guideline for the secondary prevention of Ischemic Stroke?. ### Response: EPIC-CVD case-cohort study.


Instruction: What is an EPIC-CVD case-cohort study?

Output: Guideline for the Secondary Prevention of Ischemic Stroketo non-fatal and fatal coronary heart disease and stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an EPIC-CVD case-cohort study?. ### Response: Guideline for the Secondary Prevention of Ischemic Stroketo non-fatal and fatal coronary heart disease and stroke.


Instruction: When did BMJ issue k934?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did BMJ issue k934?. ### Response: 2018.


Instruction: What does alcohol consumption and the risk of morbidity and mortality for different stroke types do?

Output: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does alcohol consumption and the risk of morbidity and mortality for different stroke types do?. ### Response: a systematic review and meta-analysis.


Instruction: What is the name of the systematic review and meta-analysis of alcohol consumption?

Output: BMC Public Health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review and meta-analysis of alcohol consumption?. ### Response: BMC Public Health.


Instruction: When did BMC Public Health publish its 10th issue?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did BMC Public Health publish its 10th issue?. ### Response: 2010.


Instruction: What is the effect of binge drinking and hy-pertension on cardiovascular disease mortality in Korean men and women?

Output: risk of serious cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of binge drinking and hy-pertension on cardiovascular disease mortality in Korean men and women?. ### Response: risk of serious cardiovascular events.


Instruction: What year was the Kangwha cohort study conducted?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the Kangwha cohort study conducted?. ### Response: 2010.


Instruction: When was the Stroke.41:2157-2162. doi: 10.1161/STROKEAHA.110.586347?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Stroke.41:2157-2162. doi: 10.1161/STROKEAHA.110.586347?. ### Response: 2010.


Instruction: Where is the National Institute on Alcohol Abuse and Alcoholism?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the National Institute on Alcohol Abuse and Alcoholism?. ### Response: https://www.niaaa.nih.gov.


Instruction: What does UNODC stand for?

Output: Crime

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does UNODC stand for?. ### Response: Crime.


Instruction: What is the name of the booklet that presents the World Drug Report?

Output: Booklet 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the booklet that presents the World Drug Report?. ### Response: Booklet 2.


Instruction: Who published the World Drug Report 2017: Booklet 2: Global Overview of Drug Demand and Supply?

Output: UNODC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the World Drug Report 2017: Booklet 2: Global Overview of Drug Demand and Supply?. ### Response: UNODC.


Instruction: When did national trends in hospitalizations for stroke associated with infective en-docarditis and opioid use occur?

Output: between 1993 and 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did national trends in hospitalizations for stroke associated with infective en-docarditis and opioid use occur?. ### Response: between 1993 and 2015.


Instruction: Between 1993 and 2015, what type of endocarditis was the most common?

Output: infective

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Between 1993 and 2015, what type of endocarditis was the most common?. ### Response: infective.


Instruction: What is the name of the study that looked at the risk of stroke in prescription and other amphetamine-type stimulants use?

Output: a systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that looked at the risk of stroke in prescription and other amphetamine-type stimulants use?. ### Response: a systematic review.


Instruction: What type of stimulants are used?

Output: amphetamine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of stimulants are used?. ### Response: amphetamine.


Instruction: What is the name of the systematic review of amphetamine-type stimulants?

Output: Drug Alcohol Rev.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of amphetamine-type stimulants?. ### Response: Drug Alcohol Rev..


Instruction: How does Cocaine use and risk of stroke compare?

Output: a systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Cocaine use and risk of stroke compare?. ### Response: a systematic review.


Instruction: What is khat chewing associated with?

Output: increased risk of stroke and death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is khat chewing associated with?. ### Response: increased risk of stroke and death.


Instruction: What is the risk of stroke and death in patients with acute coronary syndrome?

Output: khat chewing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of stroke and death in patients with acute coronary syndrome?. ### Response: khat chewing.


Instruction: When did Mayo Clin Proc. 2010:85:974–980?

Output: 172

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Mayo Clin Proc. 2010:85:974–980?. ### Response: 172.


Instruction: What is the name of the disease that affects young and middle-aged adults with ADHD?

Output: cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that affects young and middle-aged adults with ADHD?. ### Response: cardiovascular events.


Instruction: When was the last time a person had an episode of coronary syndrome?

Output: July 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a person had an episode of coronary syndrome?. ### Response: July 2021.


Instruction: What was the most recent time that a patient had a heart attack?

Output: July 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the most recent time that a patient had a heart attack?. ### Response: July 2021.


Instruction: What is atomoxetine and cerebrovascular outcomes in adults?

Output: Risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atomoxetine and cerebrovascular outcomes in adults?. ### Response: Risk.


Instruction: What are young and middle-aged adults classified as?

Output: risk of serious cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are young and middle-aged adults classified as?. ### Response: risk of serious cardiovascular events.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: Arnett et al.


Instruction: What is the DOI for the Clinical Statements and Guidlines regarding glycaemic control?

Output: 10.1161/CIR.0000000000000678 e626

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI for the Clinical Statements and Guidlines regarding glycaemic control?. ### Response: 10.1161/CIR.0000000000000678 e626.


Instruction: What is the name of the study that evaluated the effectiveness and safety of patient activation interventions for adults with type 2 diabetes?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the effectiveness and safety of patient activation interventions for adults with type 2 diabetes?. ### Response: Arnett et al.


Instruction: What are the implications for research and practice for psychosocial fac-tors in medication adherence and diabetes self-management?

Output: Implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the implications for research and practice for psychosocial fac-tors in medication adherence and diabetes self-management?. ### Response: Implications.


Instruction: What are the implications for research and practice in diabetes self-management?

Output: Psychosocial fac-tors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the implications for research and practice in diabetes self-management?. ### Response: Psychosocial fac-tors.


Instruction: What is the name of the multi-ethnic study of atherosclerosis?

Output: Social engage-ment and chronic disease risk behaviors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-ethnic study of atherosclerosis?. ### Response: Social engage-ment and chronic disease risk behaviors.


Instruction: What is the Multi-Ethnic Study of Atherosclerosis?

Output: Social engage-ment and chronic disease risk behaviors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Multi-Ethnic Study of Atherosclerosis?. ### Response: Social engage-ment and chronic disease risk behaviors.


Instruction: What are the National guidelines for smoking cessation in primary care?

Output: a literature review and evidence analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the National guidelines for smoking cessation in primary care?. ### Response: a literature review and evidence analysis.


Instruction: What is the name of the 2013 ACC/AHA guideline on the assessment of cardiovascular risk?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2013 ACC/AHA guideline on the assessment of cardiovascular risk?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What was the title of the 2014 Circulation.129:S49-73?

Output: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the 2014 Circulation.129:S49-73?. ### Response: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.


Instruction: What is the acronym for ASCVD Risk Estimator?

Output: American College of Cardiology, American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for ASCVD Risk Estimator?. ### Response: American College of Cardiology, American Heart Association.


Instruction: Where can you find this information?

Output: https://tools.acc.org/ldl/ascvd_risk_estimator/index.html#!/calulate/estimator. Accessed September 21, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find this information?. ### Response: https://tools.acc.org/ldl/ascvd_risk_estimator/index.html#!/calulate/estimator. Accessed September 21, 2018.


Instruction: When was this information available?

Output: September 21, 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this information available?. ### Response: September 21, 2018.


Instruction: What is this information used for?

Output: American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is this information used for?. ### Response: American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Instruction: What is the name of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol?

Output: Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol?. ### Response: Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.


Instruction: When did the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines publish a report?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines publish a report?. ### Response: 2019.


Instruction: What is a high incidence of coronary heart disease?

Output: coronary heart dis-ease: the Multi-Ethnic Study of Atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a high incidence of coronary heart disease?. ### Response: coronary heart dis-ease: the Multi-Ethnic Study of Atherosclerosis.


Instruction: What is the high incidence of car -diovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors?

Output: 44:2737–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the high incidence of car -diovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors?. ### Response: 44:2737–.


Instruction: Arthritis Rheum. 2001;44:2737-45. S2.2-7. Manzi S, Meilahn EN, Rairie JE, et al. Age-specific incidence rates of myocardial infarction and angina in women with what?

Output: systemic lupus erythematosus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Arthritis Rheum. 2001;44:2737-45. S2.2-7. Manzi S, Meilahn EN, Rairie JE, et al. Age-specific incidence rates of myocardial infarction and angina in women with what?. ### Response: systemic lupus erythematosus.


Instruction: What is the association between myocardial infarction and angina in women with systemic lupus erythematosus?

Output: Age-specific incidence rates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between myocardial infarction and angina in women with systemic lupus erythematosus?. ### Response: Age-specific incidence rates.


Instruction: What study was compared with the Framingham Study?

Output: Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study was compared with the Framingham Study?. ### Response: Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus.


Instruction: What is the name of the journal that was downloaded from http://ahajournals.org by on May 1, 2023?

Output: ahajournals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that was downloaded from http://ahajournals.org by on May 1, 2023?. ### Response: ahajournals.


Instruction: What is NICE 2018?

Output: Treati ng Heart Failure  Chronic Heart Failure  © NICE 2018. All rights reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: Treati ng Heart Failure  Chronic Heart Failure  © NICE 2018. All rights reserved.


Instruction: What are the Outcomes No of Participants (studies)?

Output: Follow up

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Outcomes No of Participants (studies)?. ### Response: Follow up.


Instruction: What is GRADE?

Output: Quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is GRADE?. ### Response: Quality of the evidence.


Instruction: Anticipated absolute effects Risk with Placebo Risk difference with Intravenous iron (95% CI) Improvement in NYHA class Data on i mprovement has only been extracted where quality of life data is not reported?

Output: Data on i mprovement in NYHA has only been  extracted where quality of life data is not reported in a trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anticipated absolute effects Risk with Placebo Risk difference with Intravenous iron (95% CI) Improvement in NYHA class Data on i mprovement has only been extracted where quality of life data is not reported?. ### Response: Data on i mprovement in NYHA has only been  extracted where quality of life data is not reported in a trial.


Instruction: What is extracted where quality of life data is not reported in a trial?

Output: Data on i mprovement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is extracted where quality of life data is not reported in a trial?. ### Response: Data on i mprovement.


Instruction: How many studies per 1000?

Output: 167

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies per 1000?. ### Response: 167.


Instruction: What is the risk of bias, indirectness, imprecision RR 1.2?

Output: 0.14 to 10.58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of bias, indirectness, imprecision RR 1.2?. ### Response: 0.14 to 10.58.


Instruction: What is the risk of bias, indirectness?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of bias, indirectness?. ### Response: imprecision.


Instruction: What is Peto Odds Ratio 0.11?

Output: 0.02 to 0.69

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Peto Odds Ratio 0.11?. ### Response: 0.02 to 0.69.


Instruction: What is the Peto Odds Ratio?

Output: 0.11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Peto Odds Ratio?. ### Response: 0.11.


Instruction: How many studies did Hospitalisation al l cause?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did Hospitalisation al l cause?. ### Response: 2.


Instruction: Why is Hospitalisational l a cause of 760 studies?

Output: risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is Hospitalisational l a cause of 760 studies?. ### Response: risk of bias.


Instruction: Why is LOWa, b due to risk of bias?

Output: imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is LOWa, b due to risk of bias?. ### Response: imprecision.


Instruction: What is the imprecision Rate Ratio?

Output: 0.66

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the imprecision Rate Ratio?. ### Response: 0.66.


Instruction: Moderated 383 per 1000 130 fewer per 1000 (from 57 fewer to 191 fewer) Exercise tolerance 6MWT, distance 688 (3 studies) 5.5-12 months ?

Output: 5.5-12 months  ⊕⊕⊕⊝  MODERATE b due to imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Moderated 383 per 1000 130 fewer per 1000 (from 57 fewer to 191 fewer) Exercise tolerance 6MWT, distance 688 (3 studies) 5.5-12 months ?. ### Response: 5.5-12 months  ⊕⊕⊕⊝  MODERATE b due to imprecision.


Instruction: How many studies were conducted?

Output: 16

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were conducted?. ### Response: 16.


Instruction: What was the mean exercise tolerance in the control groups?

Output: 277 m

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean exercise tolerance in the control groups?. ### Response: 277 m.


Instruction: In the intervention groups, what was the average exercise tolerance?

Output: 39.5 higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the intervention groups, what was the average exercise tolerance?. ### Response: 39.5 higher.


Instruction: How much higher was the mean haemoglobin in anaemic patients in the control groups?

Output: 9.6 g/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much higher was the mean haemoglobin in anaemic patients in the control groups?. ### Response: 9.6 g/dL.


Instruction: What was the mean haemoglobin in anaemic patients in the intervention groups?

Output: 2.1 higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean haemoglobin in anaemic patients in the intervention groups?. ### Response: 2.1 higher.


Instruction: What is the 2018 ACHD Guideline?

Output: April 2, 2019 Circulation. 2019;139:e698–e800

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 ACHD Guideline?. ### Response: April 2, 2019 Circulation. 2019;139:e698–e800.


Instruction: What are the long-term sequelae of anomalous pulmonary venous connections similar to?

Output: ASDs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the long-term sequelae of anomalous pulmonary venous connections similar to?. ### Response: ASDs.


Instruction: What is the risk of thrombosis of a surgically operated vein?

Output: low-velocity ve-nous flow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of thrombosis of a surgically operated vein?. ### Response: low-velocity ve-nous flow.


Instruction: What is a common sequelae of ASDs?

Output: anomalous pulmonary ve-nous connections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common sequelae of ASDs?. ### Response: anomalous pulmonary ve-nous connections.


Instruction: What is Section 3.4 for?

Output: rec-ommendations on diagnostic evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Section 3.4 for?. ### Response: rec-ommendations on diagnostic evaluation.


Instruction: What section is for evaluation and management of severe PAH and Eisenmenger syndrome?

Output: Section 4.4.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section is for evaluation and management of severe PAH and Eisenmenger syndrome?. ### Response: Section 4.4.6.


Instruction: Cross-sectional imaging with CMR or CTA is ideal for delineating what?

Output: pulmonary venous connections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cross-sectional imaging with CMR or CTA is ideal for delineating what?. ### Response: pulmonary venous connections.


Instruction: What is an important part of the evaluation and may identify the anomalous veins?

Output: Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an important part of the evaluation and may identify the anomalous veins?. ### Response: Echocardiography.


Instruction: CMR and CTA are superior for evaluating what?

Output: extracardiac vascular anatomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CMR and CTA are superior for evaluating what?. ### Response: extracardiac vascular anatomy.


Instruction: What is superior for evaluating extracardiac vascular anatomy?

Output: CMR and CTA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is superior for evaluating extracardiac vascular anatomy?. ### Response: CMR and CTA.


Instruction: In higher-risk patients, what can be useful for direct measurement of pressures?

Output: invasive hemodynamic assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In higher-risk patients, what can be useful for direct measurement of pressures?. ### Response: invasive hemodynamic assessment.


Instruction: What is especially important in adult patients who are being treated?

Output: Invasive hemodynamic assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is especially important in adult patients who are being treated?. ### Response: Invasive hemodynamic assessment.


Instruction: What is especially important in adult patients who are being considered for surgical correction?

Output: Invasive hemodynamic assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is especially important in adult patients who are being considered for surgical correction?. ### Response: Invasive hemodynamic assessment.


Instruction: What is unusual for a single anomalous pulmonary venous connection to result in a sufficient volume load to justify sur-gical repair?

Output: 1 pulmonary lobe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unusual for a single anomalous pulmonary venous connection to result in a sufficient volume load to justify sur-gical repair?. ### Response: 1 pulmonary lobe.


Instruction: What is a risk for adverse outcomes with surgery?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk for adverse outcomes with surgery?. ### Response: Pulmonary hypertension.


Instruction: What is associated with a reduc-tion in RV size and PA pressure?

Output: surgical repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with a reduc-tion in RV size and PA pressure?. ### Response: surgical repair.


Instruction: Surgery usually involves intracaval baffling into the left atrium, Warden procedure,S4.1.2-12 or direct reimplantation of the anomalous pulmonary vein directly into what?

Output: left atrium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Surgery usually involves intracaval baffling into the left atrium, Warden procedure,S4.1.2-12 or direct reimplantation of the anomalous pulmonary vein directly into what?. ### Response: left atrium.


Instruction: Surgical repair of a scimitar vein includes re-implantation of what into the right atrium?

Output: RV size and PA pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Surgical repair of a scimitar vein includes re-implantation of what into the right atrium?. ### Response: RV size and PA pressure.


Instruction: What is the risk of postoperative vein thrombosis?

Output: greater

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of postoperative vein thrombosis?. ### Response: greater.


Instruction: Pulmonary hypertension is associated with what?

Output: poor outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Pulmonary hypertension is associated with what?. ### Response: poor outcomes.


Instruction: What is associated with poor outcomes?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with poor outcomes?. ### Response: Pulmonary hypertension.


Instruction: What is unusual for a single anomalous pulmonary venous connection to result in a sufficient volume load to justify sur -gical repair?

Output: 1 pulmonary lobe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unusual for a single anomalous pulmonary venous connection to result in a sufficient volume load to justify sur -gical repair?. ### Response: 1 pulmonary lobe.


Instruction: How many anomalous veins are there?

Output: >1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many anomalous veins are there?. ### Response: >1.


Instruction: What is the size of the left-to-right shunt?

Output: moderate or large

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the size of the left-to-right shunt?. ### Response: moderate or large.


Instruction: How many fewer events per 1000 were there per 1000?

Output: 26

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many fewer events per 1000 were there per 1000?. ### Response: 26.


Instruction: How much was the risk of doubling of serum creatinine reduced by 30%?

Output: RR:0.70

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the risk of doubling of serum creatinine reduced by 30%?. ### Response: RR:0.70.


Instruction: What was the mean follow-up of 6759 patients?

Output: 32 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the mean follow-up of 6759 patients?. ### Response: 32 months.


Instruction: How many studies had a mean follow-up of 32 months?

Output: 8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies had a mean follow-up of 32 months?. ### Response: 8.


Instruction: How many fewer events per 1000 were there?

Output: 123

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many fewer events per 1000 were there?. ### Response: 123.