Instruction: What is the association of aortic regurgitation quantifi-cation using cardiovascular magnetic resonance with clinical outcome?

Output: Severity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of aortic regurgitation quantifi-cation using cardiovascular magnetic resonance with clinical outcome?. ### Response: Severity.


Instruction: What was the Circulation. 2012;126:1452–60?

Output: Aortic regurgitation quantifi-cation using cardiovascular magnetic resonance: association with clinical outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Circulation. 2012;126:1452–60?. ### Response: Aortic regurgitation quantifi-cation using cardiovascular magnetic resonance: association with clinical outcome.


Instruction: When was the JACC Cardiovasc Magn Reson published?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JACC Cardiovasc Magn Reson published?. ### Response: 2006.


Instruction: What is the role of cardiac magnetic resonance imaging in aortic regurgitation?

Output: Diagnostic and prognos-tic utility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of cardiac magnetic resonance imaging in aortic regurgitation?. ### Response: Diagnostic and prognos-tic utility.


Instruction: What is a possible outcome of continuous wave Doppler ultrasound?

Output: Quantification of aortic re-gurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible outcome of continuous wave Doppler ultrasound?. ### Response: Quantification of aortic re-gurgitation.


Instruction: When was the J Am Coll Car -diol published?

Output: 1986

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Car -diol published?. ### Response: 1986.


Instruction: What is the purpose of echocardiography in the eval-uation of systolic murmurs of unknown cause?

Output: Interstudy reproducibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of echocardiography in the eval-uation of systolic murmurs of unknown cause?. ### Response: Interstudy reproducibility.


Instruction: What was the name of the study that investigated the interstudy reproducibility of bi-directional ultrasound?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that investigated the interstudy reproducibility of bi-directional ultrasound?. ### Response: Otto et al.


Instruction: Infective Endocarditis in Adults 1451IE Caused by Staphylococci in the absence of what?

Output: Prosthetic Valves

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective Endocarditis in Adults 1451IE Caused by Staphylococci in the absence of what?. ### Response: Prosthetic Valves.


Instruction: Right-Sided IE in IDUsThe addition of gentamicin to what has been a standard approach for the treatment of right-sided IE?

Output: nafcillin or oxacillin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Right-Sided IE in IDUsThe addition of gentamicin to what has been a standard approach for the treatment of right-sided IE?. ### Response: nafcillin or oxacillin.


Instruction: What type of IE is treated with -lactam plus aminoglycoside therapy?

Output: right-sided S aureus IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of IE is treated with -lactam plus aminoglycoside therapy?. ### Response: right-sided S aureus IE.


Instruction: How long was the treatment of right-sided IE in IDUs?

Output: 2 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the treatment of right-sided IE in IDUs?. ### Response: 2 weeks.


Instruction: What was highly effective in several studies?

Output: combined short-course (2 weeks) β-lactam plus aminoglycoside therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was highly effective in several studies?. ### Response: combined short-course (2 weeks) β-lactam plus aminoglycoside therapy.


Instruction: In 1 study, how long did the treatment last?

Output: 2 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 1 study, how long did the treatment last?. ### Response: 2 weeks.


Instruction: How many patients pro-vided such combination therapy had excellent outcomes?

Output: 92

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients pro-vided such combination therapy had excellent outcomes?. ### Response: 92.


Instruction: What did short-course regimens with glycopeptides seem to be less effective?

Output: right-sided S aureus IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did short-course regimens with glycopeptides seem to be less effective?. ### Response: right-sided S aureus IE.


Instruction: What are two glycopeptides that appeared to be less effective for right-sided S aureus IE caused by MSSA or MRSA strains?

Output: teicoplanin or vancomycin) plus gentamicin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two glycopeptides that appeared to be less effective for right-sided S aureus IE caused by MSSA or MRSA strains?. ### Response: teicoplanin or vancomycin) plus gentamicin.


Instruction: What may be less successful because of limited bacte-ricidal activity?

Output: glycopeptides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be less successful because of limited bacte-ricidal activity?. ### Response: glycopeptides.


Instruction: What is a growing body of evidence suggesting?

Output: the addition of adjunctive aminoglycoside therapy not only is unnecessary for patients with uncomplicated right-sided native valve S aureus  IE but may cause harm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a growing body of evidence suggesting?. ### Response: the addition of adjunctive aminoglycoside therapy not only is unnecessary for patients with uncomplicated right-sided native valve S aureus  IE but may cause harm.


Instruction: What is unnecessary for patients with uncomplicated right-sided native valve S aureus IE?

Output: adjunctive aminoglycoside therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unnecessary for patients with uncomplicated right-sided native valve S aureus IE?. ### Response: adjunctive aminoglycoside therapy.


Instruction: How long was a monotherapy regimen of intravenous cloxacillin?

Output: 2-week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was a monotherapy regimen of intravenous cloxacillin?. ### Response: 2-week.


Instruction: What did the US Food and Drug Administration (FDA) approve in 2006?

Output: daptomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the US Food and Drug Administration (FDA) approve in 2006?. ### Response: daptomycin.


Instruction: How long was the monotherapy regimen of intravenous cloxacillin equivalent to?

Output: 2-week

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the monotherapy regimen of intravenous cloxacillin equivalent to?. ### Response: 2-week.


Instruction: What drug was approved for the treatment of right-sided S aureus IE?

Output: daptomycin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was approved for the treatment of right-sided S aureus IE?. ### Response: daptomycin.


Instruction: What is gentamicin used for in a clinical trial to treat S aureus bacteremia or right-sided IE?

Output: patients did equally well in either treatment arm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is gentamicin used for in a clinical trial to treat S aureus bacteremia or right-sided IE?. ### Response: patients did equally well in either treatment arm.


Instruction: What is daptomycin monotherapy used for?

Output: treatment of S aureus bacteremia and right-sided S aureus IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is daptomycin monotherapy used for?. ### Response: treatment of S aureus bacteremia and right-sided S aureus IE.


Instruction: What was the success rate of daptomycin in the predefined subgroup of those with MRSA bacteremia?

Output: 44.4%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the success rate of daptomycin in the predefined subgroup of those with MRSA bacteremia?. ### Response: 44.4%.


Instruction: What percentage of success rate was achieved with standard therapy?

Output: 31.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of success rate was achieved with standard therapy?. ### Response: 31.8%.


Instruction: How many days did patients receive gentamicin?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days did patients receive gentamicin?. ### Response: 4.


Instruction: What percentage difference was statistically significant for standard therapy?

Output: 31.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage difference was statistically significant for standard therapy?. ### Response: 31.8%.


Instruction: What was the 95% confidence interval between 7.4 to 32.6; P=0.28)?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 95% confidence interval between 7.4 to 32.6; P=0.28)?. ### Response: −.


Instruction: In a post hoc analysis, what was significantly associated with the addition of even low-dose, short-course gentamicin?

Output: renal toxic-ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In a post hoc analysis, what was significantly associated with the addition of even low-dose, short-course gentamicin?. ### Response: renal toxic-ity.


Instruction: In which arm of the study was gentamicin significantly associated with renal toxic-ity?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In which arm of the study was gentamicin significantly associated with renal toxic-ity?. ### Response: 1.


Instruction: What was the clinical association between dose and duration minimal?

Output: gentamicin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the clinical association between dose and duration minimal?. ### Response: gentamicin.


Instruction: What is the name of the trial that randomized patients with non-ST-segment elevation acute coronary syndrome to invasive management?

Output: FRISC-II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that randomized patients with non-ST-segment elevation acute coronary syndrome to invasive management?. ### Response: FRISC-II.


Instruction: What was the outcome of an interventional strategy in non ST-elevation acuity?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of an interventional strategy in non ST-elevation acuity?. ### Response: 5-year.


Instruction: When was the J Am Coll Cardiol.55:858–64.372?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol.55:858–64.372?. ### Response: 2010.


Instruction: What is a non-ST-elevation acute coronary syndrome?

Output: deferredcoronary angioplasty in non-ST-segment elevation acute coronary syn-dromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a non-ST-elevation acute coronary syndrome?. ### Response: deferredcoronary angioplasty in non-ST-segment elevation acute coronary syn-dromes.


Instruction: When was the RITA 3 trial conducted?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the RITA 3 trial conducted?. ### Response: 2005.


Instruction: What was the outcome of the CADILLAC trial?

Output: Outcome in elderly patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the CADILLAC trial?. ### Response: Outcome in elderly patients.


Instruction: What is CADILLAC?

Output: Controlled Abciximab and Device Investigation toLower Late Angioplasty Complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CADILLAC?. ### Response: Controlled Abciximab and Device Investigation toLower Late Angioplasty Complications.


Instruction: How long did the FRISC-II randomised trial last?

Output: 5-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the FRISC-II randomised trial last?. ### Response: 5-year.


Instruction: What was the outcome of the follow-up study?

Output: 5-year outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of the follow-up study?. ### Response: 5-year outcomes.


Instruction: What is the difference between immediate and delayed inter-vention for acute coronary syndromes?

Output: Immediate versus deferredcoronary angioplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between immediate and delayed inter-vention for acute coronary syndromes?. ### Response: Immediate versus deferredcoronary angioplasty.


Instruction: What is a cooling-off strategy called?

Output: pro-longed antithrombotic pretreatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cooling-off strategy called?. ### Response: pro-longed antithrombotic pretreatment.


Instruction: When was the randomized controlled trial conducted?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the randomized controlled trial conducted?. ### Response: 2005.


Instruction: What is the name of the randomized controlled trial?

Output: British Heart Foundation RITA 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled trial?. ### Response: British Heart Foundation RITA 3.


Instruction: What was the JAMA 290:1593–9.377?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the JAMA 290:1593–9.377?. ### Response: 2003.


Instruction: How long did it take for patients with acute coronary syndrome to undergo revascularization?

Output: one-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for patients with acute coronary syndrome to undergo revascularization?. ### Response: one-year.


Instruction: How are syndrome patients stratified by theGRACE risk score?

Output: In-hospital revascularization andone-year outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are syndrome patients stratified by theGRACE risk score?. ### Response: In-hospital revascularization andone-year outcome.


Instruction: How many randomised trials were there in 2003?

Output: 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomised trials were there in 2003?. ### Response: 23.


Instruction: What is the difference between primary angioplasty and intravenous thrombolytic therapy?

Output: immediatecoronary angioplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between primary angioplasty and intravenous thrombolytic therapy?. ### Response: immediatecoronary angioplasty.


Instruction: What is the difference between immediatecoronary angioplasty and intravenous streptokinase in acute myocardialinfarction?

Output: comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between immediatecoronary angioplasty and intravenous streptokinase in acute myocardialinfarction?. ### Response: comparison.


Instruction: When was the N Engl J Med 328:680–4.381?

Output: 1993

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 328:680–4.381?. ### Response: 1993.


Instruction: What year was the JAMA 291:736–9.382?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the JAMA 291:736–9.382?. ### Response: 2004.


Instruction: What is myocardial infarction withST-segment elevation?

Output: Primary PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is myocardial infarction withST-segment elevation?. ### Response: Primary PCI.


Instruction: What is the N Engl J Med. 2007:356:47–54.383?

Output: Primary PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the N Engl J Med. 2007:356:47–54.383?. ### Response: Primary PCI.


Instruction: How are hospital outcomes in patients with congestive heart failure complicating acute myocardialinfarction?

Output: cardiogenic shock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are hospital outcomes in patients with congestive heart failure complicating acute myocardialinfarction?. ### Response: cardiogenic shock.


Instruction: What is the name of the study that investigated early revascularization inacute myocardial infarction complicated by cardiogenic shock?

Output: SHOCKInvestigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated early revascularization inacute myocardial infarction complicated by cardiogenic shock?. ### Response: SHOCKInvestigators.


Instruction: What are the names of the investigators that investigated the possibility of cardiac shock in occluded coro-naries?

Output: SHOCKInvestigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the investigators that investigated the possibility of cardiac shock in occluded coro-naries?. ### Response: SHOCKInvestigators.


Instruction: When did N Engl J Med issue a report on rescue angioplasty?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue a report on rescue angioplasty?. ### Response: 1999.


Instruction: Who is the official reviewer for ACCF/AHA Task Forceon Practice Guidelines?

Output: Judith S.Hochman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the official reviewer for ACCF/AHA Task Forceon Practice Guidelines?. ### Response: Judith S.Hochman.


Instruction: What is the name of the Official Reviewer for AstraZeneca?

Output: Janet B. Long Official Reviewer—PCNA None ●AstraZeneca None None None NoneBruce W. Lytle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Official Reviewer for AstraZeneca?. ### Response: Janet B. Long Official Reviewer—PCNA None ●AstraZeneca None None None NoneBruce W. Lytle.


Instruction: Who is the official reviewer of Lytle?

Output: Douglass A.Morrison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the official reviewer of Lytle?. ### Response: Douglass A.Morrison.


Instruction: What is the name of the Official Reviewer?

Output: E. MagnusOhman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Official Reviewer?. ### Response: E. MagnusOhman.


Instruction: When was Stable Ischemic Heart Disease: Full Text e467 downloaded?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Stable Ischemic Heart Disease: Full Text e467 downloaded?. ### Response: May 1, 2023.


Instruction: What is the date of the update to 2017 ECDP for Optimization of Heart Failure Treatment?

Output: FEBRUARY 16, 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the date of the update to 2017 ECDP for Optimization of Heart Failure Treatment?. ### Response: FEBRUARY 16, 2021.


Instruction: How long was the follow-up in the Veterans Affairs Cooperative Study of Coronary Artery Bypass Surgery for stable angina?

Output: Eighteen-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the follow-up in the Veterans Affairs Cooperative Study of Coronary Artery Bypass Surgery for stable angina?. ### Response: Eighteen-year.


Instruction: What year did Circulation 1992;86:121–30.350?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circulation 1992;86:121–30.350?. ### Response: 1992.


Instruction: How long did the Veterans Administration Coronary artery bypass surgery Coop-erative Study Group survive?

Output: Eleven-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Veterans Administration Coronary artery bypass surgery Coop-erative Study Group survive?. ### Response: Eleven-year.


Instruction: What is the name of the randomized trial of coronary bypass surgery for stable angina?

Output: Randomized IschemicMitral Evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of coronary bypass surgery for stable angina?. ### Response: Randomized IschemicMitral Evaluation.


Instruction: What is HEART?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HEART?. ### Response: American Heart Association.


Instruction: What type of bypass surgery is used in patients with left ventricular dysfunction?

Output: Coronary-artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of bypass surgery is used in patients with left ventricular dysfunction?. ### Response: Coronary-artery.


Instruction: What is the difference between a transcatheter and surgical aortic-valve replacement in high-risk patients?

Output: cannot undergosurgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between a transcatheter and surgical aortic-valve replacement in high-risk patients?. ### Response: cannot undergosurgery.


Instruction: What is the name of the procedure used to treat aortic stenosis in patients who cannot undergo surgery?

Output: Transcatheter aortic-valveimplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used to treat aortic stenosis in patients who cannot undergo surgery?. ### Response: Transcatheter aortic-valveimplantation.


Instruction: What is CASS?

Output: poor left ventricular function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CASS?. ### Response: poor left ventricular function.


Instruction: How many patients were treated with CASS in 1983?

Output: 68:785

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with CASS in 1983?. ### Response: 68:785.


Instruction: What is the acronym for left ventricular function?

Output: CASS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for left ventricular function?. ### Response: CASS.


Instruction: Circulation 1983;68:785-95.356.

Output: Circula-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation 1983;68:785-95.356.. ### Response: Circula-tion.


Instruction: What are the appropriateness criteria for coronary revasculariza-tion?

Output: with or without surgical ventricular reconstruction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the appropriateness criteria for coronary revasculariza-tion?. ### Response: with or without surgical ventricular reconstruction.


Instruction: What is the acronym for Society of Thoracic Surgeons?

Output: Society for Cardiovascular Angi-ography and Interventions, Society of Thoracic Surgeons, AmericanAssociation for Thoracic Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Society of Thoracic Surgeons?. ### Response: Society for Cardiovascular Angi-ography and Interventions, Society of Thoracic Surgeons, AmericanAssociation for Thoracic Surgery.


Instruction: What are the acronyms for American Heart Association and American Society of Nuclear Cardiology?

Output: AmericanAssociation for Thoracic Surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the acronyms for American Heart Association and American Society of Nuclear Cardiology?. ### Response: AmericanAssociation for Thoracic Surgery.


Instruction: When was the J Am Coll Cardiol published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol published?. ### Response: 2009.


Instruction: What is the final result of the Randomized IschemicMitral Evaluation (RIME) trial?

Output: Coronary artery bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the final result of the Randomized IschemicMitral Evaluation (RIME) trial?. ### Response: Coronary artery bypass surgery.


Instruction: What did Sampognaro R, Baldus S, and Franzen O have to say about the effectiveness of adding mitral valve restrictive annuloplasty to coronary artery bypassgrafting?

Output: ﬁcacy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Sampognaro R, Baldus S, and Franzen O have to say about the effectiveness of adding mitral valve restrictive annuloplasty to coronary artery bypassgrafting?. ### Response: ﬁcacy.


Instruction: What is the name of the therapy used in patients with end-stage systolic heart failure?

Output: MitraClip /C210therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the therapy used in patients with end-stage systolic heart failure?. ### Response: MitraClip /C210therapy.


Instruction: When did Eur J Heart Fail 2011 issue 13:569–76.361?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Heart Fail 2011 issue 13:569–76.361?. ### Response: 2011.


Instruction: What was done with or without surgical ventricular reconstruction?

Output: Coronary bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was done with or without surgical ventricular reconstruction?. ### Response: Coronary bypass surgery.


Instruction: What does McAlister FA do?

Output: Structured telephone supportor telemonitoring programmes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does McAlister FA do?. ### Response: Structured telephone supportor telemonitoring programmes.


Instruction: What does Coleman EA, Boult C. believe about transitional care for patients with heart failure?

Output: Improving the quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Coleman EA, Boult C. believe about transitional care for patients with heart failure?. ### Response: Improving the quality.


Instruction: What type of natriuretic peptide is used in the assessment of acute dyspnoea?

Output: Plasma brain

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of natriuretic peptide is used in the assessment of acute dyspnoea?. ### Response: Plasma brain.


Instruction: What is the name of the journal that describes the rapid measurement of B-type natruretic?

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that describes the rapid measurement of B-type natruretic?. ### Response: Lancet.


Instruction: When was the journal published?

Output: 2006;98:386–90. 28. Januzzi JL Jr, Chen-Tournoux AA, Moe G. Amino-terminal pro-B-type na-triuretic peptide testing for the diagnosis or exclusion of heart failure in patients with acute symptoms. Am J Cardiol. 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the journal published?. ### Response: 2006;98:386–90. 28. Januzzi JL Jr, Chen-Tournoux AA, Moe G. Amino-terminal pro-B-type na-triuretic peptide testing for the diagnosis or exclusion of heart failure in patients with acute symptoms. Am J Cardiol. 2008.


Instruction: What is natriuretic peptide used for in the emergency diagnosis of heart failure?

Output: Rapid measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is natriuretic peptide used for in the emergency diagnosis of heart failure?. ### Response: Rapid measurement.


Instruction: When did N Engl J Med issue 347:161–7?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 347:161–7?. ### Response: 2002.


Instruction: What improves the management of patients with suspected acute heart failure: primary results of the Canadian prospective randomized multicenter IMPROVE-CHF study?

Output: N-terminal pro-B-type natriuretic peptide testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What improves the management of patients with suspected acute heart failure: primary results of the Canadian prospective randomized multicenter IMPROVE-CHF study?. ### Response: N-terminal pro-B-type natriuretic peptide testing.


Instruction: What is the name of the Canadian prospective random-ized multicenter IMPROVE-CHF study?

Output: N-terminal pro-B-type natriuretic peptide testing improves the management of patients with suspected acute heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Canadian prospective random-ized multicenter IMPROVE-CHF study?. ### Response: N-terminal pro-B-type natriuretic peptide testing improves the management of patients with suspected acute heart failure.


Instruction: What type of pep-tide is used in the evaluation and management of acute dyspnea?

Output: B-type natriuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of pep-tide is used in the evaluation and management of acute dyspnea?. ### Response: B-type natriuretic.


Instruction: When did N Engl J Med. 2004;350:647–54?

Output: 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med. 2004;350:647–54?. ### Response: 27.


Instruction: What is the usefulness of in-termediate amino-terminal pro-brain natriuretic peptide concentra-tions for?

Output: diagnosis and prognosis of acute heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the usefulness of in-termediate amino-terminal pro-brain natriuretic peptide concentra-tions for?. ### Response: diagnosis and prognosis of acute heart failure.


Instruction: What is used for the diagnosis and prognosis of acute heart failure?

Output: in-termediate amino-terminal pro-brain natriuretic peptide concentra-tions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used for the diagnosis and prognosis of acute heart failure?. ### Response: in-termediate amino-terminal pro-brain natriuretic peptide concentra-tions.


Instruction: What is the name of the systematic review of natriuretic peptide measurement in ADHF?

Output: Heart Fail Rev. 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of natriuretic peptide measurement in ADHF?. ### Response: Heart Fail Rev. 2014.


Instruction: What is a term for acute decompensated heart failure?

Output: ADHF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for acute decompensated heart failure?. ### Response: ADHF.


Instruction: In what year was the Am J Cardiol published?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was the Am J Cardiol published?. ### Response: 2006.


Instruction: What is used for the diagnosis of heart failure in the emergency department?

Output: BNP and NT-proBNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used for the diagnosis of heart failure in the emergency department?. ### Response: BNP and NT-proBNP.


Instruction: What is the name of the systematic review of the evidence for the use of BNP and NT-proBNP?

Output: Heart Fail

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of the evidence for the use of BNP and NT-proBNP?. ### Response: Heart Fail.


Instruction: What is the determinant and detection of left ventricular dysfunction in the gener -al community?

Output: Amino-terminal pro-B-type natriuretic peptide and B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the determinant and detection of left ventricular dysfunction in the gener -al community?. ### Response: Amino-terminal pro-B-type natriuretic peptide and B-type natriuretic peptide.


Instruction: What is de Lemos JA, McGuire DK, Khera A, et al?

Output: 32

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is de Lemos JA, McGuire DK, Khera A, et al?. ### Response: 32.


Instruction: What did the Dallas Heart Study do?

Output: Screening the population for left ventricular hypertrophy and left ventricular systolic dysfunction us-ing natriuretic peptides

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Dallas Heart Study do?. ### Response: Screening the population for left ventricular hypertrophy and left ventricular systolic dysfunction us-ing natriuretic peptides.


Instruction: What did Goetze JP, Mogelvang R, Maage L, et al. screen for?

Output: left ventricular hypertro-phy and systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Goetze JP, Mogelvang R, Maage L, et al. screen for?. ### Response: left ventricular hypertro-phy and systolic dysfunction.


Instruction: What is screening for left ventricular hypertro-phy and systolic dysfunction?

Output: Plasma pro-B-type natriuretic peptide in the general population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is screening for left ventricular hypertro-phy and systolic dysfunction?. ### Response: Plasma pro-B-type natriuretic peptide in the general population.


Instruction: What is natriuretic peptide in the general population?

Output: Plasma pro-B-type

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is natriuretic peptide in the general population?. ### Response: Plasma pro-B-type.


Instruction: When did Eur Heart J. 2006 release 27:3004-10?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 2006 release 27:3004-10?. ### Response: 2006.


Instruction: What is a marker of cardiac fibrosis that pre-dicts incident heart failure in the community?

Output: Galectin-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a marker of cardiac fibrosis that pre-dicts incident heart failure in the community?. ### Response: Galectin-3.


Instruction: What is Galectin-3?

Output: a marker of cardiac fibrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Galectin-3?. ### Response: a marker of cardiac fibrosis.


Instruction: When did J Am Coll Cardiol. 2012 issue 60: 1249–56?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2012 issue 60: 1249–56?. ### Response: 2012.


Instruction: What is the Framingham Heart Study?

Output: Prognostic utility of novel bio-markers of cardiovascular stress

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Framingham Heart Study?. ### Response: Prognostic utility of novel bio-markers of cardiovascular stress.


Instruction: What is a novel biomarker of cardiovascular stress?

Output: bio-markers of cardiovascular stress: the Framingham Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a novel biomarker of cardiovascular stress?. ### Response: bio-markers of cardiovascular stress: the Framingham Heart Study.


Instruction: What type of patients have MI.2163?

Output: Very high-risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients have MI.2163?. ### Response: Very high-risk.


Instruction: What are very high-risk patients?

Output: those with history of multiple major ASCVD events or 1 major ASCVD event and multiple high-risk conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are very high-risk patients?. ### Response: those with history of multiple major ASCVD events or 1 major ASCVD event and multiple high-risk conditions.


Instruction: How much LDL-C is > 70 mg/dL (1.8 mmol/L)?

Output: LDL-C lower-ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much LDL-C is > 70 mg/dL (1.8 mmol/L)?. ### Response: LDL-C lower-ing.


Instruction: How many RCTs demonstrated non-high-density lipoprotein >100 mg/dL by ezetimibe and 2 PCSK9 inhibitors?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs demonstrated non-high-density lipoprotein >100 mg/dL by ezetimibe and 2 PCSK9 inhibitors?. ### Response: 3.


Instruction: What guideline strongly recommends that ezetimibe be added to maximal tol-erated statin as a first step to further lower LDL-C?

Output: COR 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What guideline strongly recommends that ezetimibe be added to maximal tol-erated statin as a first step to further lower LDL-C?. ### Response: COR 1.


Instruction: What was ezetimibe allowed at entry with statin therapy in both PCSK9 inhibitor trials?

Output: FOURIER [Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk]

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was ezetimibe allowed at entry with statin therapy in both PCSK9 inhibitor trials?. ### Response: FOURIER [Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk].


Instruction: What is the acronym for Fourier?

Output: Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Fourier?. ### Response: Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk.


Instruction: How many subjects received ezetimibe during these trials?

Output: 3% and 5%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many subjects received ezetimibe during these trials?. ### Response: 3% and 5%.


Instruction: What is available as a generic drug and has proven safety?

Output: ezetimibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is available as a generic drug and has proven safety?. ### Response: ezetimibe.


Instruction: ezeti-mibe plus statin therapy lowers LDL-C to 70 mg/dL (1.8 mmol/L) in most patients, leaving a minority eligible for what?

Output: PCSK9 inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ezeti-mibe plus statin therapy lowers LDL-C to 70 mg/dL (1.8 mmol/L) in most patients, leaving a minority eligible for what?. ### Response: PCSK9 inhibitor.


Instruction: What did the TST trial of patients with ischemic stroke use as second-line therapy to achieve the LDL-C Table 5?

Output: ezeti-mibe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the TST trial of patients with ischemic stroke use as second-line therapy to achieve the LDL-C Table 5?. ### Response: ezeti-mibe.


Instruction: What is a very high risk of future ASCVD events?

Output: a history of multiple major ASCVD events or 1 major ASCVD event and multiple high-risk conditions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a very high risk of future ASCVD events?. ### Response: a history of multiple major ASCVD events or 1 major ASCVD event and multiple high-risk conditions.


Instruction: How many major ASCVD events does a person have?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many major ASCVD events does a person have?. ### Response: 1.


Instruction: How many high-risk conditions are there?

Output: multiple

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many high-risk conditions are there?. ### Response: multiple.


Instruction: What is a history of?

Output: claudication with ankle-brachial index <0.85 or previous revascularization or amputation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a history of?. ### Response: claudication with ankle-brachial index <0.85 or previous revascularization or amputation.


Instruction: History of MI (other than recent ACS event listed above)

Output: myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: History of MI (other than recent ACS event listed above). ### Response: myocardial infarction.


Instruction: What type of arterial disease has a history of claudication with ankle-brachial index 0.85 or previous revascularization or amputation High-risk conditions Age 65 y Heterozygous familial hypercholesterolemia History of coronary artery bypass surgery or percutaneous coronary intervention outside of the major ASCVD events Diabetes Hypertension Chronic kidney disease (estimated glomerular filtration rate, 15–59 mLmin11.73?

Output: Symptomatic peripheral arterial disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of arterial disease has a history of claudication with ankle-brachial index 0.85 or previous revascularization or amputation High-risk conditions Age 65 y Heterozygous familial hypercholesterolemia History of coronary artery bypass surgery or percutaneous coronary intervention outside of the major ASCVD events Diabetes Hypertension Chronic kidney disease (estimated glomerular filtration rate, 15–59 mLmin11.73?. ### Response: Symptomatic peripheral arterial disease.


Instruction: What is the estimated glomerular filtration rate of chronic kidney disease?

Output: 15–59 mL·min−1·1.73 m−2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the estimated glomerular filtration rate of chronic kidney disease?. ### Response: 15–59 mL·min−1·1.73 m−2.


Instruction: What does the 2018 AHA/ACC Guideline on the Management of Blood Cholesterol recommend?

Output: atorvastatin 80 mg daily or rosuvastatin 20 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the 2018 AHA/ACC Guideline on the Management of Blood Cholesterol recommend?. ### Response: atorvastatin 80 mg daily or rosuvastatin 20 mg daily.


Instruction: For high-intensity statin therapy, what does the guideline recommend for 80 mg daily?

Output: atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For high-intensity statin therapy, what does the guideline recommend for 80 mg daily?. ### Response: atorvastatin.


Instruction: What is rosuvastatin 20 mg daily?

Output: high-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rosuvastatin 20 mg daily?. ### Response: high-intensity statin therapy.


Instruction: What does ACS mean?

Output: acute coronary syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACS mean?. ### Response: acute coronary syndrome.


Instruction: How does ASCVD refer to atherosclerotic cardiovascular disease?

Output: History of ischemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does ASCVD refer to atherosclerotic cardiovascular disease?. ### Response: History of ischemic stroke.


Instruction: What is reasonable for fibrotic or calcified lesions that might not be crossed by a balloon catheter or adequately dilated before stentimplantation?

Output: Rotational atherectomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable for fibrotic or calcified lesions that might not be crossed by a balloon catheter or adequately dilated before stentimplantation?. ### Response: Rotational atherectomy.


Instruction: What is a marker for significant CAD and increased long-term mortality?

Output: coronary calcification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a marker for significant CAD and increased long-term mortality?. ### Response: coronary calcification.


Instruction: What is not a homogenous entity?

Output: Calci-fied coronary lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not a homogenous entity?. ### Response: Calci-fied coronary lesions.


Instruction: What varies according to severity of calcification?

Output: Calci-fied coronary lesions are not a homogenous entity, and theirresponse to PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What varies according to severity of calcification?. ### Response: Calci-fied coronary lesions are not a homogenous entity, and theirresponse to PCI.


Instruction: When was the 2011 ACCF/AHA/SCAI PCI Guideline released?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2011 ACCF/AHA/SCAI PCI Guideline released?. ### Response: May 1, 2023.


Instruction: What is the largest series of E faecalis IE reported to date?

Output: these 2 studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the largest series of E faecalis IE reported to date?. ### Response: these 2 studies.


Instruction: How many patients were in the first study?

Output: 43

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were in the first study?. ### Response: 43.


Instruction: What was the second study used to treat high-level aminoglycoside-resistant E aeca-lis IE?

Output: ampicillin-ceftriaxone therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the second study used to treat high-level aminoglycoside-resistant E aeca-lis IE?. ### Response: ampicillin-ceftriaxone therapy.


Instruction: What was present in 50% of the patients in the smaller study?

Output: high-level aminoglycoside-resistant E faeca-lis IE treated with ampicillin-ceftriaxone therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was present in 50% of the patients in the smaller study?. ### Response: high-level aminoglycoside-resistant E faeca-lis IE treated with ampicillin-ceftriaxone therapy.


Instruction: What percentage of patients had nephrotoxicity with ampicillin-ceftriaxone ther-apy?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients had nephrotoxicity with ampicillin-ceftriaxone ther-apy?. ### Response: none.


Instruction: How many of the 87 ampicillin gentamicin-treated patients had what drug?

Output: 23%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many of the 87 ampicillin gentamicin-treated patients had what drug?. ### Response: 23%).


Instruction: What percentage of ampicillin-gentamicin-treated patients developed nephrotoxicity?

Output: 23%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of ampicillin-gentamicin-treated patients developed nephrotoxicity?. ### Response: 23%).


Instruction: What was the median age in the larger study?

Output: 70 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median age in the larger study?. ### Response: 70 years.


Instruction: Patients in what group were generally sicker and had more comorbid conditions?

Output: ampicillin-ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients in what group were generally sicker and had more comorbid conditions?. ### Response: ampicillin-ceftriaxone.


Instruction: What was present in 59 percent of patients treated with ampicillin-ceftriaxone and 30% with gentamicin with similar success rates?

Output: PVE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was present in 59 percent of patients treated with ampicillin-ceftriaxone and 30% with gentamicin with similar success rates?. ### Response: PVE.


Instruction: In the larger study, there were no significant differences in what?

Output: ampicillin-ceftriaxone and ampicillin-gentamicin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the larger study, there were no significant differences in what?. ### Response: ampicillin-ceftriaxone and ampicillin-gentamicin.


Instruction: What was the only difference between ampicillin-ceftriaxone and gentamicin in the larger study?

Output: need for surgery, complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the only difference between ampicillin-ceftriaxone and gentamicin in the larger study?. ### Response: need for surgery, complications.


Instruction: What were the overall microbiological cure and success rates for both studies?

Output: similar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the overall microbiological cure and success rates for both studies?. ### Response: similar.


Instruction: What are the major advantages of the ampicillin-ceftriaxone regi-men?

Output: lower risk of nephrotoxicity and the lack of need for measuring aminoglycoside serum concentrations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the major advantages of the ampicillin-ceftriaxone regi-men?. ### Response: lower risk of nephrotoxicity and the lack of need for measuring aminoglycoside serum concentrations.


Instruction: What is the potential disadvantage of using ampicillin and ceftrixone regimens?

Output: hypersensitivity reactions to 2 separate β-lactams

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the potential disadvantage of using ampicillin and ceftrixone regimens?. ### Response: hypersensitivity reactions to 2 separate β-lactams.


Instruction: The success rates of what were similar to those of previous studies?

Output: ampicillin-ceftriaxone and ampicillin-gentamicin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The success rates of what were similar to those of previous studies?. ### Response: ampicillin-ceftriaxone and ampicillin-gentamicin.


Instruction: What is a potential disadvantage of measuring aminoglycoside serum concentrations?

Output: hypersensitivity reactions to 2 separate β-lactams

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a potential disadvantage of measuring aminoglycoside serum concentrations?. ### Response: hypersensitivity reactions to 2 separate β-lactams.


Instruction: What would be discontinued with substitution of vancomycin-gentamicin therapy?

Output: ampicillin or to ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be discontinued with substitution of vancomycin-gentamicin therapy?. ### Response: ampicillin or to ceftriaxone.


Instruction: Why would it not be possible to discriminate between hypersensitivities related to ampicillin or ceftriaxone?

Output: Because it would likely not be possible to discriminate between hypersensitivities related to ampicillin or to ceftriaxone, both drugs might have to be discontinued with substitution of vancomycin-gentamicin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why would it not be possible to discriminate between hypersensitivities related to ampicillin or ceftriaxone?. ### Response: Because it would likely not be possible to discriminate between hypersensitivities related to ampicillin or to ceftriaxone, both drugs might have to be discontinued with substitution of vancomycin-gentamicin therapy.


Instruction: What was discontinued with substitution of vancomycin-gentamicin therapy?

Output: ampicillin or to ceftriaxone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was discontinued with substitution of vancomycin-gentamicin therapy?. ### Response: ampicillin or to ceftriaxone.


Instruction: What does the writing group advocate for each patient?

Output: individualized approach to regimen selection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing group advocate for each patient?. ### Response: individualized approach to regimen selection.


Instruction: How long of therapy is reasonable for NVE?

Output: 4 or 6 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long of therapy is reasonable for NVE?. ### Response: 4 or 6 weeks.


Instruction: What is the class IIa of NVE therapy?

Output: Level of Evidence B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class IIa of NVE therapy?. ### Response: Level of Evidence B.


Instruction: How long is the level of evidence B of aqueous crystalline penicillin?

Output: Six weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the level of evidence B of aqueous crystalline penicillin?. ### Response: Six weeks.


Instruction: How long of therapy is reasonable if ampicillin plus ceftriaxone is selected as the treatment regimen?

Output: Six weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long of therapy is reasonable if ampicillin plus ceftriaxone is selected as the treatment regimen?. ### Response: Six weeks.


Instruction: What is the class of evidence for six weeks of antimicrobial therapy?

Output: Class IIa; Level of Evidence B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of evidence for six weeks of antimicrobial therapy?. ### Response: Class IIa; Level of Evidence B.


Instruction: How many weeks of antimicrobial therapy is reasonable for PVE (Class IIa; Level of Evidence B)?

Output: Six weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many weeks of antimicrobial therapy is reasonable for PVE (Class IIa; Level of Evidence B)?. ### Response: Six weeks.


Instruction: IOM Standards for Systematic Reviews Part of the KDIGO Process?

Output: Methods to appraise the quality of individual studies Yes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: IOM Standards for Systematic Reviews Part of the KDIGO Process?. ### Response: Methods to appraise the quality of individual studies Yes.


Instruction: Methods to appraise the quality of individual studies Yes  Summary measures of effect size (e.g., risk ratio, difference in means) No  Rationale for pooling (or not pooling) results of included studies?

Output:  Methods to appraise the quality of individual studies Yes 

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Methods to appraise the quality of individual studies Yes  Summary measures of effect size (e.g., risk ratio, difference in means) No  Rationale for pooling (or not pooling) results of included studies?. ### Response:  Methods to appraise the quality of individual studies Yes .


Instruction: What are two methods of synthesizing the evidence used for?

Output: qualitative and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two methods of synthesizing the evidence used for?. ### Response: qualitative and meta-analysis.


Instruction: What should be included in the results section?

Output: Additional analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be included in the results section?. ### Response: Additional analyses.


Instruction: What section of the systematic review should include a summary of the evidence?

Output: rationale sections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section of the systematic review should include a summary of the evidence?. ### Response: rationale sections.


Instruction: What is included in the section describing funding sources and limitations?

Output: COI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in the section describing funding sources and limitations?. ### Response: COI.


Instruction: What is included in a section of the draft report?

Output: funding sources and COI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in a section of the draft report?. ### Response: funding sources and COI.


Instruction: Who manages the peer review process?

Output: Use a third party

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who manages the peer review process?. ### Response: Use a third party.


Instruction: What does a peer reviewer do?

Output: Use a third party to manage the peer review process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a peer reviewer do?. ### Response: Use a third party to manage the peer review process.


Instruction: What is the purpose of releasing the final report?

Output: ensures free public access

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the purpose of releasing the final report?. ### Response: ensures free public access.


Instruction: What is a way to ensure free public access?

Output: Publish the final report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a way to ensure free public access?. ### Response: Publish the final report.


Instruction: What is not written up as a separate report?

Output: The systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not written up as a separate report?. ### Response: The systematic review.


Instruction: There is no stand-alone discussion on section.

Output: The systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no stand-alone discussion on section.. ### Response: The systematic review.


Instruction: How is the evidence summarized in individual rationale sections of the guideline?

Output: as needed to support the recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the evidence summarized in individual rationale sections of the guideline?. ### Response: as needed to support the recommendations.


Instruction: What are there no key questions for which to write conclusions?

Output: what is summarized as needed in the rationale for the recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are there no key questions for which to write conclusions?. ### Response: what is summarized as needed in the rationale for the recommendations.


Instruction: What is discussed to support the recommendations?

Output: Gaps in the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is discussed to support the recommendations?. ### Response: Gaps in the evidence.


Instruction: What is there a public comment period for?

Output: the report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is there a public comment period for?. ### Response: the report.


Instruction: How is the guideline published?

Output: in a manner that ensures free pub lic access

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the guideline published?. ### Response: in a manner that ensures free pub lic access.


Instruction: What is not a stand-alone review?

Output: The systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not a stand-alone review?. ### Response: The systematic review.


Instruction: Infective endocarditis in congenital heart disease: Japanese national collaboration study. Heart. 2005;91:795–800. doi: 10.1136/hrt.2004.043323?

Output: 146

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis in congenital heart disease: Japanese national collaboration study. Heart. 2005;91:795–800. doi: 10.1136/hrt.2004.043323?. ### Response: 146.


Instruction: Infective endocarditis: reassessment of what prognostic implications?

Output: rapid versus prolonged healing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infective endocarditis: reassessment of what prognostic implications?. ### Response: rapid versus prolonged healing.


Instruction: What are the prognostic implications of vegetation size determined by the transthoracic and the transesophageal approach?

Output: rapid versus prolonged healing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the prognostic implications of vegetation size determined by the transthoracic and the transesophageal approach?. ### Response: rapid versus prolonged healing.


Instruction: When did J Am Coll Cardiol. 1989:14:631–638?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 1989:14:631–638?. ### Response: 1989.


Instruction: What were the predictors of embolic events in pediatric infective endocarditis?

Output: antibiotic therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the predictors of embolic events in pediatric infective endocarditis?. ### Response: antibiotic therapy.


Instruction: What is the name of the journal that studies the healing of infective endocarditis?

Output: NEJM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the healing of infective endocarditis?. ### Response: NEJM.


Instruction: What are the names of the authors of the study?

Output: Niwa K, Nakazawa M, Tateno S, Yoshinaga M, Terai M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the authors of the study?. ### Response: Niwa K, Nakazawa M, Tateno S, Yoshinaga M, Terai M.


Instruction: How does vegetation size compare to healing?

Output: rapid versus prolonged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does vegetation size compare to healing?. ### Response: rapid versus prolonged.


Instruction: What year did Echocardiogr. 1991:4:465–474?

Output: 1989

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Echocardiogr. 1991:4:465–474?. ### Response: 1989.


Instruction: What is the name of the Japanese Society of Pediatric Cardiology and Cardiac Surgery?

Output: Yoshinaga M, Niwa K, Niwa A, Ishiwada N, Takahashi H, Echigo S, Nakazawa M

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Japanese Society of Pediatric Cardiology and Cardiac Surgery?. ### Response: Yoshinaga M, Niwa K, Niwa A, Ishiwada N, Takahashi H, Echigo S, Nakazawa M.


Instruction: When did Am Heart J. 1994:128(pt 1):1200–1209?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Am Heart J. 1994:128(pt 1):1200–1209?. ### Response: 1994.


Instruction: What is the Japanese Society of Pediatric Cardiology and Cardiac Surgery?

Output: 151

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Japanese Society of Pediatric Cardiology and Cardiac Surgery?. ### Response: 151.


Instruction: What are the risk factors for in-hospital mortality during infective en-docarditis in patients with congenital heart disease?

Output: 152

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the risk factors for in-hospital mortality during infective en-docarditis in patients with congenital heart disease?. ### Response: 152.


Instruction: What is the name of the early surgery treatment for infective endocarditis?

Output: conventional treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the early surgery treatment for infective endocarditis?. ### Response: conventional treatment.


Instruction: When was the N Engl J Med 366:2466–2473 published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 366:2466–2473 published?. ### Response: 2012.


Instruction: What is a management-based approach used to reduce infective endocar-ditis-related mortality?

Output: Dramatic reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a management-based approach used to reduce infective endocar-ditis-related mortality?. ### Response: Dramatic reduction.


Instruction: What is the doi number for the study?

Output: 10.1136/hrt.2004.043323

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi number for the study?. ### Response: 10.1136/hrt.2004.043323.


Instruction: What is the risk of embolization after institution of antibiotic therapy for infective endocarditis?

Output: 155

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of embolization after institution of antibiotic therapy for infective endocarditis?. ### Response: 155.


Instruction: When did J Am Coll Cardiol. 2002;39:1489–1495?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2002;39:1489–1495?. ### Response: 2002.


Instruction: What was the name of the prospective study that showed improved diagnostic value of echocardiography in patients with infective endocarditis?

Output: transoesophageal approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the prospective study that showed improved diagnostic value of echocardiography in patients with infective endocarditis?. ### Response: transoesophageal approach.


Instruction: What did Meyer J, Dismukes WE, and Douglas JL do?

Output: Prediction of rapid versus prolonged healing of infective endocarditis by monitoring vegetation size

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Meyer J, Dismukes WE, and Douglas JL do?. ### Response: Prediction of rapid versus prolonged healing of infective endocarditis by monitoring vegetation size.


Instruction: Where was Kaye D, ed., published?

Output: Raven Press

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was Kaye D, ed., published?. ### Response: Raven Press.


Instruction: What is the name of the 2nd ed. in Endocarditis?

Output: Kaye D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2nd ed. in Endocarditis?. ### Response: Kaye D.


Instruction: When was the 2d edutain?

Output: 1992

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2d edutain?. ### Response: 1992.


Instruction: Where was the 3rd edition?

Output: New York, NY: Raven Press

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the 3rd edition?. ### Response: New York, NY: Raven Press.


Instruction: What was the Surgical management of infective endo-carditus in children?

Output: management-based approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Surgical management of infective endo-carditus in children?. ### Response: management-based approach.


Instruction: What is active endocarditis in children called?

Output: Operative in-tervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is active endocarditis in children called?. ### Response: Operative in-tervention.


Instruction: What is the name of the study that reported a series of cases and a review?

Output: Operative in-tervention in active endocarditis in children

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that reported a series of cases and a review?. ### Response: Operative in-tervention in active endocarditis in children.


Instruction: What is the target range of DM or proteinuria?

Output: X1g/24 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the target range of DM or proteinuria?. ### Response: X1g/24 h.


Instruction: What is a diastolic BP:o80 mm Hg?

Output: target range120–129 mm Hg) and diastolic BP:o80 mm Hg unless the risks areconsidered to outweighthe potential benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a diastolic BP:o80 mm Hg?. ### Response: target range120–129 mm Hg) and diastolic BP:o80 mm Hg unless the risks areconsidered to outweighthe potential benefits.


Instruction: What should be avoided?

Output: lowering thesystolic blood pressure too120 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be avoided?. ### Response: lowering thesystolic blood pressure too120 mm Hg.


Instruction: What should not be used as a firstchoice agent?

Output: DKDand DKDCKD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be used as a firstchoice agent?. ### Response: DKDand DKDCKD.


Instruction: What is recommended for patients with persistent microalbuminuria?

Output: ACE-I or or ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with persistent microalbuminuria?. ### Response: ACE-I or or ARB.


Instruction: What is ACE-I or ARB recommended as?

Output: initialtherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACE-I or ARB recommended as?. ### Response: initialtherapy.


Instruction: What is recommended as initialtherapy?

Output: ACE-I or or ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended as initialtherapy?. ### Response: ACE-I or or ARB.


Instruction: What should be considered for patients with microalbuminuria or overtnephropathyo130/80

Output: ACE-I or ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered for patients with microalbuminuria or overtnephropathyo130/80. ### Response: ACE-I or ARB.


Instruction: What is the acronym for angiotensin-converting enzyme inhibitor?

Output: ACE-I

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for angiotensin-converting enzyme inhibitor?. ### Response: ACE-I.


Instruction: What does ACR stand for?

Output: albumin/creatinine ratio

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ACR stand for?. ### Response: albumin/creatinine ratio.


Instruction: ARB stands for what?

Output: angiotensin-receptor blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ARB stands for what?. ### Response: angiotensin-receptor blocker.


Instruction: What did the committee emphasize the importance of?

Output: any service that provides IC Ds

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee emphasize the importance of?. ### Response: any service that provides IC Ds.


Instruction: What was not sought for this review question?

Output: Economic studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not sought for this review question?. ### Response: Economic studies.


Instruction: What did the committee consider the recommendations ma de above represent?

Output: best clinical practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee consider the recommendations ma de above represent?. ### Response: best clinical practice.


Instruction: What could patients be able to do if they are well informed?

Output: improved quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could patients be able to do if they are well informed?. ### Response: improved quality of life.


Instruction: What could improve the quality of life for patients?

Output: If patients are well informed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could improve the quality of life for patients?. ### Response: If patients are well informed.


Instruction: What could reduce the number of painful unwanted shocks for individuals?

Output: informed decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could reduce the number of painful unwanted shocks for individuals?. ### Response: informed decision making.


Instruction: What can shocks do for individuals?

Output: improvement in quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can shocks do for individuals?. ### Response: improvement in quality of life.


Instruction: What could shocks help improve?

Output: quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could shocks help improve?. ### Response: quality of life.


Instruction: What is the optimal anticoagulation strategy to use before or during urgent cardioversion for patients with AFand hemodynamic instability?

Output: thromboprophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the optimal anticoagulation strategy to use before or during urgent cardioversion for patients with AFand hemodynamic instability?. ### Response: thromboprophylaxis.


Instruction: What did our systematic review find no publisheddata regarding?

Output: the optimal anticoagulation strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did our systematic review find no publisheddata regarding?. ### Response: the optimal anticoagulation strategy.


Instruction: What would be expected to reduce the risk of stroke/thromboembolism?

Output: initiation of anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be expected to reduce the risk of stroke/thromboembolism?. ### Response: initiation of anticoagulation.


Instruction: What should not delay any emergency interventions required in order to stabilize the patient?

Output: Initiation ofanticoagulation therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not delay any emergency interventions required in order to stabilize the patient?. ### Response: Initiation ofanticoagulation therapy.


Instruction: What should be done for patients with AF and hemodynamicinstability undergoing urgent cardioversion?

Output: therapeutic-dose parenteral anticoagulation bestarted before cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be done for patients with AF and hemodynamicinstability undergoing urgent cardioversion?. ### Response: therapeutic-dose parenteral anticoagulation bestarted before cardioversion.


Instruction: What must not delay anyemergency intervention?

Output: initiation of anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must not delay anyemergency intervention?. ### Response: initiation of anticoagulation.


Instruction: What do we suggest for patients with AF and hemodynamicinstability undergoing urgent cardioversion?

Output: therapeutic-dose parenteral anticoagulation bestarted before cardioversion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest for patients with AF and hemodynamicinstability undergoing urgent cardioversion?. ### Response: therapeutic-dose parenteral anticoagulation bestarted before cardioversion.


Instruction: How long after successful cardioversion to sinus rhythm do we recommendtherapeutic anticoagulation?

Output: 4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after successful cardioversion to sinus rhythm do we recommendtherapeutic anticoagulation?. ### Response: 4 weeks.


Instruction: What is the baseline stroke risk?

Output: thromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the baseline stroke risk?. ### Response: thromboembolism.


Instruction: What should be made in accordance with ourrisk-based recommendations for long-termantithrombotic therapy in recommendations 1 and 2?

Output: Decisions about anticoagulation beyond4 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be made in accordance with ourrisk-based recommendations for long-termantithrombotic therapy in recommendations 1 and 2?. ### Response: Decisions about anticoagulation beyond4 weeks.


Instruction: What are there no specific trials which have consideredelectrical cardioversion in the context of?

Output: atrial ﬂutter andassociated anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are there no specific trials which have consideredelectrical cardioversion in the context of?. ### Response: atrial ﬂutter andassociated anticoagulation.


Instruction: What is considered electric cardioversion in the context of atrial flutter andassociated anticoagulation?

Output: urgent pharmacologic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered electric cardioversion in the context of atrial flutter andassociated anticoagulation?. ### Response: urgent pharmacologic.


Instruction: What has been suggested by some observational studies?

Output: low risk ofthromboembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been suggested by some observational studies?. ### Response: low risk ofthromboembolism.


Instruction: Why have other studies shown a similar risk of thromboembolism?

Output: co-existence of AF and atrial ﬂutter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why have other studies shown a similar risk of thromboembolism?. ### Response: co-existence of AF and atrial ﬂutter.


Instruction: How many patients had cardioversion for atrial flutter and AF?

Output: 234,274,275

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had cardioversion for atrial flutter and AF?. ### Response: 234,274,275.


Instruction: What is a growing population of adults with congenital heart disease with atrialflutter?

Output: important

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a growing population of adults with congenital heart disease with atrialflutter?. ### Response: important.


Instruction: What should be used for patients with atrial fibrillation undergoing cardioversion?

Output: thromboprophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used for patients with atrial fibrillation undergoing cardioversion?. ### Response: thromboprophylaxis.


Instruction: What commonly coexists with vasculardisease, whether coronary, carotid or PAD?

Output: Patients With AF With Coronary ArteryDiseaseACS and/or PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What commonly coexists with vasculardisease, whether coronary, carotid or PAD?. ### Response: Patients With AF With Coronary ArteryDiseaseACS and/or PCI.


Instruction: What may a patient with coronary disease present with?

Output: an ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may a patient with coronary disease present with?. ### Response: an ACS.


Instruction: What may present with an ACS?

Output: AF patients with coronary disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may present with an ACS?. ### Response: AF patients with coronary disease.


Instruction: What is exercise and physical activity used for in the prevention and treatment of atherosclerotic cardiovascular disease?

Output: prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is exercise and physical activity used for in the prevention and treatment of atherosclerotic cardiovascular disease?. ### Response: prevention.


Instruction: What is a statement from the American Heart Association?

Output: Exercise training for systolic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a statement from the American Heart Association?. ### Response: Exercise training for systolic heart failure.


Instruction: What is a subcommittee on Exercise, Rehabilitation, and Prevention?

Output: Council on Clinical Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a subcommittee on Exercise, Rehabilitation, and Prevention?. ### Response: Council on Clinical Cardiology.


Instruction: What is the subcomitee of Physical Activity?

Output: Council on Nutrition, Physical Activity, and Metabolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the subcomitee of Physical Activity?. ### Response: Council on Nutrition, Physical Activity, and Metabolism.


Instruction: When was Circulation published?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation published?. ### Response: 2003.


Instruction: Adamopoulos S, Anker SD, Auricchio A, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Lip GY, Parkhomenko A, Pieske BM, Rnnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A,

Output: 10.1161/01.CIR.0000075572

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adamopoulos S, Anker SD, Auricchio A, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Lip GY, Parkhomenko A, Pieske BM, Rnnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A,. ### Response: 10.1161/01.CIR.0000075572.


Instruction: What is the name of the ESC Committee for Practice Guidelines?

Output: Stepinska J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ESC Committee for Practice Guidelines?. ### Response: Stepinska J.


Instruction: What does ESC call the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure?

Output: ESC Committee for Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ESC call the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure?. ### Response: ESC Committee for Practice Guidelines.


Instruction: What is Chronic Heart Failure 2012 of the European Society of Cardiology?

Output: the Task Force for the Diagnosis and Treatment of Acute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chronic Heart Failure 2012 of the European Society of Cardiology?. ### Response: the Task Force for the Diagnosis and Treatment of Acute.


Instruction: What does Eur Heart J. 2012:33:1787–1847?

Output: doi: 10.1093/eurheartj/ehs104.318

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Eur Heart J. 2012:33:1787–1847?. ### Response: doi: 10.1093/eurheartj/ehs104.318.


Instruction: What is the consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation?

Output: Exercise training in heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation?. ### Response: Exercise training in heart failure.


Instruction: Exercise training in heart failure: from theory to practice.

Output: a consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise training in heart failure: from theory to practice.. ### Response: a consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation.


Instruction: Cardiovascular Prevention and Rehabilitation. 2011;13:347–357. doi: 10.1093/eurjhf/hfr017.

Output: 10.1161/01.CIR.0000075572

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Cardiovascular Prevention and Rehabilitation. 2011;13:347–357. doi: 10.1093/eurjhf/hfr017.. ### Response: 10.1161/01.CIR.0000075572.