Instruction: What is the name of the 2019 AHA/ACC High Blood Pressure Performance and Quality MeasuresCirc Cardiovasc Qual Outcomes. 2019;12:e000057?

Output: Casey et al;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2019 AHA/ACC High Blood Pressure Performance and Quality MeasuresCirc Cardiovasc Qual Outcomes. 2019;12:e000057?. ### Response: Casey et al;.


Instruction: What does HCQ.0000000000000057 stand for?

Output: High Blood Pressure Performance and Quality Measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does HCQ.0000000000000057 stand for?. ### Response: High Blood Pressure Performance and Quality Measures.


Instruction: What did the 2014 expert panel recommendations for management of high blood pressure do?

Output: insights from the NCDR PINNACLE registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2014 expert panel recommendations for management of high blood pressure do?. ### Response: insights from the NCDR PINNACLE registry.


Instruction: What registry did the NCDR PINNACLE registry gain insights from?

Output: contempo-rary cardiovascular practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What registry did the NCDR PINNACLE registry gain insights from?. ### Response: contempo-rary cardiovascular practice.


Instruction: What year did JAMA publish its 310th issue?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did JAMA publish its 310th issue?. ### Response: 2013.


Instruction: What is the name of the study that aimed to identify undiagnosed hypertension in primary care patients?

Output: Ohasama study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that aimed to identify undiagnosed hypertension in primary care patients?. ### Response: Ohasama study.


Instruction: What is hypertension among active primary care patients?

Output: undiagnosed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hypertension among active primary care patients?. ### Response: undiagnosed.


Instruction: What is Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged 75 years?

Output: a randomized clinical trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged 75 years?. ### Response: a randomized clinical trial.


Instruction: What is the name of the mul-ticenter clinical trial comparing two strategies for control of systolic blood pressure?

Output: Systolic Blood Pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the mul-ticenter clinical trial comparing two strategies for control of systolic blood pressure?. ### Response: Systolic Blood Pressure.


Instruction: What does SPRINT stand for?

Output: Systolic Blood Pressure Intervention Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does SPRINT stand for?. ### Response: Systolic Blood Pressure Intervention Trial.


Instruction: What was the name of the ACCORD trial?

Output: Action to Control Cardiovascular Risk in Diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the ACCORD trial?. ### Response: Action to Control Cardiovascular Risk in Diabetes.


Instruction: What is the name given to the Action to Control Cardiovascular Risk in Diabetes?

Output: ACCORD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name given to the Action to Control Cardiovascular Risk in Diabetes?. ### Response: ACCORD.


Instruction: When was the Am J Cardiol. 2007:99:44i–55i?

Output: 61

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol. 2007:99:44i–55i?. ### Response: 61.


Instruction: What affects risk estimates associated with white-coat and masked hypertension in the population?

Output: Setting thresholds to varying blood pressure monitoring intervals

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What affects risk estimates associated with white-coat and masked hypertension in the population?. ### Response: Setting thresholds to varying blood pressure monitoring intervals.


Instruction: What does Fagard RH, Cornelissen VA do?

Output: Incidence of cardiovascular events in white-coat, masked and sustained hypertension versus true normotension: a meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Fagard RH, Cornelissen VA do?. ### Response: Incidence of cardiovascular events in white-coat, masked and sustained hypertension versus true normotension: a meta-analysis.


Instruction: Incidence of cardiovascular events in what group?

Output: adults aged ≥75 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Incidence of cardiovascular events in what group?. ### Response: adults aged ≥75 years.


Instruction: What is the name of the meta-analysis?

Output: hypertension versus true normotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis?. ### Response: hypertension versus true normotension.


Instruction: What is a long term prognostic value of white coat hypertension?

Output: an insight from diagnostic use of both ambulatory and home blood pressure measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a long term prognostic value of white coat hypertension?. ### Response: an insight from diagnostic use of both ambulatory and home blood pressure measurements.


Instruction: Where is the National Clinical Guideline Centre?

Output: UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the National Clinical Guideline Centre?. ### Response: UK.


Instruction: What is the name of the NICE Clinical Guidelines for adults?

Output: cg127

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the NICE Clinical Guidelines for adults?. ### Response: cg127.


Instruction: Where is the Royal College of Physicians based?

Output: London, UK: Royal College of Physicians (UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Royal College of Physicians based?. ### Response: London, UK: Royal College of Physicians (UK.


Instruction: When was the publication published?

Output: July 15, 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the publication published?. ### Response: July 15, 2019.


Instruction: What is masked hypertension?

Output: hyperten-sion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is masked hypertension?. ### Response: hyperten-sion.


Instruction: What type of hypertension was detected by ambulatory blood pressure monitoring?

Output: white-coat

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypertension was detected by ambulatory blood pressure monitoring?. ### Response: white-coat.


Instruction: How long did the Ohasama study follow-up?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Ohasama study follow-up?. ### Response: 10-year.


Instruction: What was the name of the study that measured white coat hypertension?

Output: Ohasama

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that measured white coat hypertension?. ### Response: Ohasama.


Instruction: What is the VA/DoD CPG f or the Management of Dyslipidemia for Cardiovascular Risk Reduction?

Output: Patient -centered Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD CPG f or the Management of Dyslipidemia for Cardiovascular Risk Reduction?. ### Response: Patient -centered Care.


Instruction: When is the Provider Summary?

Output: June 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the Provider Summary?. ### Response: June 2020.


Instruction: Who is M. Eric Rodgers, PhD, FNP-BC?

Output: James Sall

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is M. Eric Rodgers, PhD, FNP-BC?. ### Response: James Sall.


Instruction: Who is Rodgers?

Output: M. Eric Rodgers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Rodgers?. ### Response: M. Eric Rodgers.


Instruction: What is Rene Sutton's BS?

Output: HCA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Rene Sutton's BS?. ### Response: HCA.


Instruction: Who is Devlin?

Output: U.S. Army Medical Command

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Devlin?. ### Response: U.S. Army Medical Command.


Instruction: The Lewin Group Clifford Goodman, PhD Christine Jones, MS, MPH, PMP Erika Beam, MS Ben Agatston, JD, MSCE Ruben Ganesh, BSECRI James Reston, PhD Jeff Oris Taglio, PhD Joann Fontanarosa, PhD

Output: Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Lewin Group Clifford Goodman, PhD Christine Jones, MS, MPH, PMP Erika Beam, MS Ben Agatston, JD, MSCE Ruben Ganesh, BSECRI James Reston, PhD Jeff Oris Taglio, PhD Joann Fontanarosa, PhD. ### Response: Group.


Instruction: Jeff Oris taglio, PhD Joann Fontanarosa, PhD Kristy McShea, MSLIS Benjamin Rouse, MHS Nancy Sullivan, MD Sigma Health Consulting Frances Murphy, MD, MPH Duty First Consulting Rachel Piccolino, BA

Output: Patient -centered care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Jeff Oris taglio, PhD Joann Fontanarosa, PhD Kristy McShea, MSLIS Benjamin Rouse, MHS Nancy Sullivan, MD Sigma Health Consulting Frances Murphy, MD, MPH Duty First Consulting Rachel Piccolino, BA. ### Response: Patient -centered care.


Instruction: What is the 2020 Dyslipidemia CPG an update to?

Output: 2014 VA/DoD Dyslipidemia  CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 Dyslipidemia CPG an update to?. ### Response: 2014 VA/DoD Dyslipidemia  CPG.


Instruction: What is Rachel Piccolino's profession?

Output: Duty First Consulting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Rachel Piccolino's profession?. ### Response: Duty First Consulting.


Instruction: What is an update to the 2014 VA/DoD Dyslipidemia CPG?

Output: The 2020 Dyslipidemia  CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an update to the 2014 VA/DoD Dyslipidemia CPG?. ### Response: The 2020 Dyslipidemia  CPG.


Instruction: What does the methodology used in developing the 202 0 CPG follow?

Output: Guideline for Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the methodology used in developing the 202 0 CPG follow?. ### Response: Guideline for Guidelines.


Instruction: When was the Guideline for Guidelines updated?

Output: January 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Guideline for Guidelines updated?. ### Response: January 2019.


Instruction: What can be downloaded from http://www.healthquality.va.gov/policy/i ndex.asp?

Output: The Guideline for Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be downloaded from http://www.healthquality.va.gov/policy/i ndex.asp?. ### Response: The Guideline for Guidelines.


Instruction: What VA/DoD CPGs encourage a patient centered care approach?

Output: Patient -centered Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What VA/DoD CPGs encourage a patient centered care approach?. ### Response: Patient -centered Care.


Instruction: What should all patients be able to access?

Output: evidence -based care that is appropriate to them

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all patients be able to access?. ### Response: evidence -based care that is appropriate to them.


Instruction: What should be available to people with physical, sensory, or learning disabilities?

Output: limited literacy skills

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be available to people with physical, sensory, or learning disabilities?. ### Response: limited literacy skills.


Instruction: What type of care may decrease patient anxiety?

Output: Patient -centered care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care may decrease patient anxiety?. ### Response: Patient -centered care.


Instruction: Good communication is essential and should be supported by what?

Output: evidence -based information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Good communication is essential and should be supported by what?. ### Response: evidence -based information.


Instruction: How is information tailored to the patient's needs?

Output: evidence -based

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is information tailored to the patient's needs?. ### Response: evidence -based.


Instruction: What facilitates discussions s ensitive to gender, culture, ethnicity, and other differences?

Output: An empathetic and non -judgmental approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What facilitates discussions s ensitive to gender, culture, ethnicity, and other differences?. ### Response: An empathetic and non -judgmental approach.


Instruction: How does the focus use an individual's risk factors and event history?

Output: to guide the various treatment and management strategies among patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the focus use an individual's risk factors and event history?. ### Response: to guide the various treatment and management strategies among patients.


Instruction: What is the name of a group of patients at risk for CVD morbidity and mortality?

Output: The Lewin Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a group of patients at risk for CVD morbidity and mortality?. ### Response: The Lewin Group.


Instruction: How many Stroke December 20141998 Guidelines for the Management of Patients With Valvular Heart Disease). Circulation. 2008;118:e523–e661. 461. Barletta GA, Gagliardi R, Benvenuti L, Fantini F. Cerebral ischemic attacks as a complication of aortic and mitral valve prolapse.

Output: 3820

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Stroke December 20141998 Guidelines for the Management of Patients With Valvular Heart Disease). Circulation. 2008;118:e523–e661. 461. Barletta GA, Gagliardi R, Benvenuti L, Fantini F. Cerebral ischemic attacks as a complication of aortic and mitral valve prolapse.. ### Response: 3820.


Instruction: How many strokes were there in young patients in 1985?

Output: 219–223

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many strokes were there in young patients in 1985?. ### Response: 219–223.


Instruction: What is the association between stroke and mitral-valve pro-lapse?

Output: Lack of evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between stroke and mitral-valve pro-lapse?. ### Response: Lack of evidence.


Instruction: When did N Engl J Med issue 341:8-13?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 341:8-13?. ### Response: 1999.


Instruction: What is the prevalence and clinical outcome of mitral-valve prolapse?

Output: Prevalence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence and clinical outcome of mitral-valve prolapse?. ### Response: Prevalence.


Instruction: What was the N Engl J Med. 1999;341:1–7. 464?

Output: Prevalence and clinical outcome of mitral-valve prolapse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med. 1999;341:1–7. 464?. ### Response: Prevalence and clinical outcome of mitral-valve prolapse.


Instruction: What is a community-based study of incidence and predictive factors after diagnosis of mitral valve prolapse?

Output: chemic events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a community-based study of incidence and predictive factors after diagnosis of mitral valve prolapse?. ### Response: chemic events.


Instruction: Stroke. 2003;34:1339–1344. What is the risk of stroke in an elderly cohort?

Output: 465

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stroke. 2003;34:1339–1344. What is the risk of stroke in an elderly cohort?. ### Response: 465.


Instruction: What is the risk of stroke in an elderly cohort?

Output: Mitral annular calcification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of stroke in an elderly cohort?. ### Response: Mitral annular calcification.


Instruction: What was the N Engl J Med. 1992;327:374–379.

Output: Mitral annular calcification

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the N Engl J Med. 1992;327:374–379.. ### Response: Mitral annular calcification.


Instruction: What is the Strong Heart Study?

Output: Mitral annu-lar calcification, aortic valve sclerosis, and incident stroke in adults free of clinical cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Strong Heart Study?. ### Response: Mitral annu-lar calcification, aortic valve sclerosis, and incident stroke in adults free of clinical cardiovascular disease.


Instruction: How many people died from stroke in 2005?

Output: 467

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people died from stroke in 2005?. ### Response: 467.


Instruction: What was the impact of mitral annular calcification on?

Output: cardiovascu-lar events in a multiethnic community

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the impact of mitral annular calcification on?. ### Response: cardiovascu-lar events in a multiethnic community.


Instruction: What is the name of the multiethnic community study?

Output: Northern Manhattan Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multiethnic community study?. ### Response: Northern Manhattan Study.


Instruction: What was the JACC Cardiovasc Imaging. 2008:1:617-623?

Output: Northern Manhattan Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the JACC Cardiovasc Imaging. 2008:1:617-623?. ### Response: Northern Manhattan Study.


Instruction: How many patients were com-parisoned in the Meta-analysis of complications in aortic valve replacement?

Output: 8,536

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were com-parisoned in the Meta-analysis of complications in aortic valve replacement?. ### Response: 8,536.


Instruction: When did Catheter cardiovasc Interv. 2012:80:128–138?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Catheter cardiovasc Interv. 2012:80:128–138?. ### Response: 2012.


Instruction: How many patients underwent valve replacement in 2012?

Output: 8,536

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent valve replacement in 2012?. ### Response: 8,536.


Instruction: What is the risk of thromboemboli early after a bioprosthetic cardiac valve replacement?

Output: High risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of thromboemboli early after a bioprosthetic cardiac valve replacement?. ### Response: High risk.


Instruction: What is the name of the medical journal published in 1995?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the medical journal published in 1995?. ### Response: J Am Coll Cardiol.


Instruction: What is one of the complications of mechanical heart valve prostheses?

Output: Thromboembolic and bleed-ing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the complications of mechanical heart valve prostheses?. ### Response: Thromboembolic and bleed-ing.


Instruction: How many patients were treated with cardiac valve prosthesis in 1994?

Output: 471

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with cardiac valve prosthesis in 1994?. ### Response: 471.


Instruction: What is the name of the journal that deals with thrombotic therapy in prosthetic heart valves?

Output: Chest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that deals with thrombotic therapy in prosthetic heart valves?. ### Response: Chest.


Instruction: What are the names of the journals that deal with heart valve therapy?

Output: ET, Best LG, Resnick HE, Roman MJ, Devereux RB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the journals that deal with heart valve therapy?. ### Response: ET, Best LG, Resnick HE, Roman MJ, Devereux RB.


Instruction: Who is the author of the study?

Output: Strong Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study?. ### Response: Strong Heart Study.


Instruction: What is the difference between Dabigatran and warfarin in patients with cancer?

Output: Dabigatran

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between Dabigatran and warfarin in patients with cancer?. ### Response: Dabigatran.


Instruction: Who is the RE-ALIGN Investigator?

Output: Eikelboom JW, Connolly SJ, Brueckmann M, Granger CB, Kappetein AP, Mack MJ, Blatchford J, Devenny K, Friedman J, Guiver K, Harper R, Khder Y , Lobmeyer MT, Maas H, V oigt JU, Simoons ML, Van de Werf F

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the RE-ALIGN Investigator?. ### Response: Eikelboom JW, Connolly SJ, Brueckmann M, Granger CB, Kappetein AP, Mack MJ, Blatchford J, Devenny K, Friedman J, Guiver K, Harper R, Khder Y , Lobmeyer MT, Maas H, V oigt JU, Simoons ML, Van de Werf F.


Instruction: Reporting of outcomes was inconsistent across what studies?

Output: Somestudies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Reporting of outcomes was inconsistent across what studies?. ### Response: Somestudies.


Instruction: Somestudies assessed thromboembolic and bleeding outcomes for what?

Output: indications other than VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Somestudies assessed thromboembolic and bleeding outcomes for what?. ### Response: indications other than VTE.


Instruction: What did the panel rate down certainty for?

Output: indirectness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the panel rate down certainty for?. ### Response: indirectness.


Instruction: What tool did the McMaster GRADE Centre use to prepare aGRADE EtD table for each guideline question?

Output: GRADEpro Guideline Development Tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tool did the McMaster GRADE Centre use to prepare aGRADE EtD table for each guideline question?. ### Response: GRADEpro Guideline Development Tool.


Instruction: The GRADEpro Guideline Development Tool is available at what website?

Output: gradepro.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The GRADEpro Guideline Development Tool is available at what website?. ### Response: gradepro.org.


Instruction: What did the guideline panel review before, during, or after the meeting?

Output: EtD tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the guideline panel review before, during, or after the meeting?. ### Response: EtD tables.


Instruction: What was the EtD table about?

Output: desirable andundesirable effects of interventions, certainty in the evidence, valuesand preferences (relative importance of outcomes), resource use,health equity, acceptability, and feasibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the EtD table about?. ### Response: desirable andundesirable effects of interventions, certainty in the evidence, valuesand preferences (relative importance of outcomes), resource use,health equity, acceptability, and feasibility.


Instruction: What did the guideline panel make suggestions for?

Output: improvement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the guideline panel make suggestions for?. ### Response: improvement.


Instruction: What was updated during February and March 2017?

Output: searches

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was updated during February and March 2017?. ### Response: searches.


Instruction: Who directed researchers to follow the methods outlined in the Cochrane Handbook forSystematic Reviews of Interventions?

Output: McMaster GRADE Centre

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who directed researchers to follow the methods outlined in the Cochrane Handbook forSystematic Reviews of Interventions?. ### Response: McMaster GRADE Centre.


Instruction: What was accepted and checked for when existing reviews were used?

Output: accuracy or conducted de novo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was accepted and checked for when existing reviews were used?. ### Response: accuracy or conducted de novo.


Instruction: How was risk of bias assessed for new reviews?

Output: at the outcome level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was risk of bias assessed for new reviews?. ### Response: at the outcome level.


Instruction: What tool did the Cochrane Collaboration use for randomized trials and nonrandomized studies?

Output: risk-of-bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tool did the Cochrane Collaboration use for randomized trials and nonrandomized studies?. ### Response: risk-of-bias.


Instruction: How did researchers search for evidence related to intervention effects?

Output: summarized findings withinthe EtD frameworks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did researchers search for evidence related to intervention effects?. ### Response: summarized findings withinthe EtD frameworks.


Instruction: What is another name for the certainty in the body of evidence?

Output: quality of the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the certainty in the body of evidence?. ### Response: quality of the evidence.


Instruction: What was assessed for each of the effects estimate of outcomes?

Output: the certainty in the body ofevidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was assessed for each of the effects estimate of outcomes?. ### Response: the certainty in the body ofevidence.


Instruction: What approach assessed the risk of bias, precision, consistency and magnitude of theestimates of effects, directness of the evidence, risk of publicationbias, presence of a dose-effect relationship, and importance of outcomes?

Output: GRADE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What approach assessed the risk of bias, precision, consistency and magnitude of theestimates of effects, directness of the evidence, risk of publicationbias, presence of a dose-effect relationship, and importance of outcomes?. ### Response: GRADE.


Instruction: Evidence, risk of publicationbias, presence of a dose-effect relationship, and an assessment of the effect of residual, opposing confounding?

Output: precision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence, risk of publicationbias, presence of a dose-effect relationship, and an assessment of the effect of residual, opposing confounding?. ### Response: precision.


Instruction: How many levels was the certainty categorised into?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many levels was the certainty categorised into?. ### Response: 4.


Instruction: What did the panel develop clinical recommendations based on?

Output: theevidence summarized in the EtD tables

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the panel develop clinical recommendations based on?. ### Response: theevidence summarized in the EtD tables.


Instruction: What was developed based on the evidence summarized in the EtD tables?

Output: clinical recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was developed based on the evidence summarized in the EtD tables?. ### Response: clinical recommendations.


Instruction: What did thepanel take a population perspective?

Output: For each recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did thepanel take a population perspective?. ### Response: For each recommendation.


Instruction: How many mm Hg at baseline did SPRINT use to identify increased CVD risk?

Output: 139

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mm Hg at baseline did SPRINT use to identify increased CVD risk?. ### Response: 139.


Instruction: What was the Framingham 10-year risk of general CVD exceeding 15%?

Output: increased CVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Framingham 10-year risk of general CVD exceeding 15%?. ### Response: increased CVD risk.


Instruction: What was the 10-year ASCVD risk per the ACC/AHA Pooled Cohort Equations?

Output: 6% to 7%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 10-year ASCVD risk per the ACC/AHA Pooled Cohort Equations?. ### Response: 6% to 7%.


Instruction: What did most of the participants in SPRINT have a much higher level of?

Output: CVD risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did most of the participants in SPRINT have a much higher level of?. ### Response: CVD risk.


Instruction: What does CKD stand for?

Output: diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does CKD stand for?. ### Response: diabetes.


Instruction: What is a patient with a SBP/DBP 140/90 mm Hg likely to benefit from?

Output: BP lowering drug therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a patient with a SBP/DBP 140/90 mm Hg likely to benefit from?. ### Response: BP lowering drug therapy.


Instruction: When was the BP Downloaded from http://ahajournals.org by?

Output: May 3, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the BP Downloaded from http://ahajournals.org by?. ### Response: May 3, 2023.


Instruction: What did Kulik et al Secondary Prevention After CABG 9311 randomly select to evaluate the extent of graft intimal hyperplasia?

Output: vein graft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Kulik et al Secondary Prevention After CABG 9311 randomly select to evaluate the extent of graft intimal hyperplasia?. ### Response: vein graft.


Instruction: What combination of aspirin plus clopido-grel did not significantly reduce the development of?

Output: vein graft intimal hyperplasia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What combination of aspirin plus clopido-grel did not significantly reduce the development of?. ### Response: vein graft intimal hyperplasia.


Instruction: How long after CABG was graft patency measured?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after CABG was graft patency measured?. ### Response: 1 year.


Instruction: What was the overall patency of the grafted patency?

Output: 95.2%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall patency of the grafted patency?. ### Response: 95.2%.


Instruction: How much was the vein patency difference between the two groups at 1 year?

Output: 94.3% versus 93.2%, aspi-rin and clopidogrel versus aspirin; P=0.69) were not different

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the vein patency difference between the two groups at 1 year?. ### Response: 94.3% versus 93.2%, aspi-rin and clopidogrel versus aspirin; P=0.69) were not different.


Instruction: How long did the groups last?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the groups last?. ### Response: 1 year.


Instruction: What did investigators from the ROOBY trial evaluate?

Output: the impact of clopidogrel use on graft patency 1 year after surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did investigators from the ROOBY trial evaluate?. ### Response: the impact of clopidogrel use on graft patency 1 year after surgery.


Instruction: How long after surgery did the investigators evaluate the impact of clopidogrel use?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after surgery did the investigators evaluate the impact of clopidogrel use?. ### Response: 1 year.


Instruction: How many meta-analyses have assessed the potential benefits of dual antiplatelet therapy after CABG?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many meta-analyses have assessed the potential benefits of dual antiplatelet therapy after CABG?. ### Response: 3.


Instruction: How many ran-domized trials were included in the largest meta-analysis on the subject?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ran-domized trials were included in the largest meta-analysis on the subject?. ### Response: 5.


Instruction: What percentage of patients received clopidogrel after surgery?

Output: 86.5%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients received clopidogrel after surgery?. ### Response: 86.5%).


Instruction: How many ran-domized trials were included in the largest meta-analysis on vein graft occlusion?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many ran-domized trials were included in the largest meta-analysis on vein graft occlusion?. ### Response: 5.


Instruction: How many observational studies included >25 000 patients?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many observational studies included >25 000 patients?. ### Response: 6.


Instruction: What was the RR of dual antiplatelet therapy compared to aspirin alone?

Output: 0.59

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of dual antiplatelet therapy compared to aspirin alone?. ### Response: 0.59.


Instruction: What has not been shown to improve postoperative vein graft patency?

Output: combination antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been shown to improve postoperative vein graft patency?. ### Response: combination antiplatelet therapy.


Instruction: What is clopidogrel added to to aspirin to improve?

Output: postoperative vein graft patency

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel added to to aspirin to improve?. ### Response: postoperative vein graft patency.


Instruction: What is most pronounced after off-pump CABG?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is most pronounced after off-pump CABG?. ### Response: clopidogrel.


Instruction: What was found to significantly increase the risk of major bleeding after surgery?

Output: Dual anti-platelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to significantly increase the risk of major bleeding after surgery?. ### Response: Dual anti-platelet therapy.


Instruction: How many new agents have recently been introduced?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many new agents have recently been introduced?. ### Response: 2.


Instruction: What does prasu-grel and ticagrelor inhibit?

Output: platelet P2Y12 adenosine diphos-phate receptor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does prasu-grel and ticagrelor inhibit?. ### Response: platelet P2Y12 adenosine diphos-phate receptor.


Instruction: What is the P2Y12 adenosine diphos-phate receptor?

Output: clopi-dogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the P2Y12 adenosine diphos-phate receptor?. ### Response: clopi-dogrel.


Instruction: When was Prasugrel first evaluated?

Output: Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel–Thrombolysis in Myocardial Infarction 38 (TRITON-TIMI 38) study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Prasugrel first evaluated?. ### Response: Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel–Thrombolysis in Myocardial Infarction 38 (TRITON-TIMI 38) study.


Instruction: Prasugrel was first evaluated in what study?

Output: Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel–Thrombolysis in Myocardial Infarction 38

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prasugrel was first evaluated in what study?. ### Response: Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel–Thrombolysis in Myocardial Infarction 38.


Instruction: How many patients presented with acute coronary syndromes were given aspirin plus clopidogrel 75 mg daily?

Output: 13 608

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients presented with acute coronary syndromes were given aspirin plus clopidogrel 75 mg daily?. ### Response: 13 608.


Instruction: What was the pri-mary outcome for patients who received prasugrel?

Output: 86.5%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the pri-mary outcome for patients who received prasugrel?. ### Response: 86.5%).


Instruction: What percentage of patients died from nonfatal MI or stroke after receiving clopidogrel compared to placebo?

Output: 86.5%)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients died from nonfatal MI or stroke after receiving clopidogrel compared to placebo?. ### Response: 86.5%).


Instruction: How long did it take for patients to receive aspirin plus clopigrel 75 mg daily or 10 mg daily?

Output: 6 to 15 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for patients to receive aspirin plus clopigrel 75 mg daily or 10 mg daily?. ### Response: 6 to 15 months.


Instruction: What was the difference between prasugrel and clopidogrel?

Output: 12.1%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the difference between prasugrel and clopidogrel?. ### Response: 12.1%,.


Instruction: How often should you take 425 mg every 12 h?

Output: extended release

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often should you take 425 mg every 12 h?. ### Response: extended release.


Instruction: What should be monitored with hepatic impairment?

Output: dosage reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be monitored with hepatic impairment?. ### Response: dosage reduction.


Instruction: Sinus or AV conduction disease (in absence of pacemaker)• Cardiogenic shock• Hypotension• Reactive airway disease Avoid in what?

Output: structural heart disease (including ischemic heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sinus or AV conduction disease (in absence of pacemaker)• Cardiogenic shock• Hypotension• Reactive airway disease Avoid in what?. ### Response: structural heart disease (including ischemic heart disease.


Instruction: What is Brugada syndrome?

Output: Hepatic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Brugada syndrome?. ### Response: Hepatic dysfunction.


Instruction: What are drugs with SA and/or AV nodal–blocking properties?

Output: Drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are drugs with SA and/or AV nodal–blocking properties?. ### Response: Drugs.


Instruction: What is the term for comprehensive specialized stroke care that incorporates rehabilitation?

Output: stroke units

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for comprehensive specialized stroke care that incorporates rehabilitation?. ### Response: stroke units.


Instruction: What is standardized stroke care?

Output: order sets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is standardized stroke care?. ### Response: order sets.


Instruction: What is recommended to improve general management?

Output: The use of standardized stroke care order sets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to improve general management?. ### Response: The use of standardized stroke care order sets.


Instruction: What is unchanged from 2013 AIS Guidelines?

Output: I C-EORecommendation and COR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unchanged from 2013 AIS Guidelines?. ### Response: I C-EORecommendation and COR.


Instruction: How was LOE amended?

Output: to conform with ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was LOE amended?. ### Response: to conform with ACC/AHA 2015 Recommendation Classification System.


Instruction: How many sizable trials have evaluated the effect of flat versus elevated head position after a stroke?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sizable trials have evaluated the effect of flat versus elevated head position after a stroke?. ### Response: 1.


Instruction: What is HeadPoST?

Output: Head Positioning in Acute Stroke Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is HeadPoST?. ### Response: Head Positioning in Acute Stroke Trial.


Instruction: What was the name of the large international, cluster-randomized, crossover open-label trial that enrolled any patient hospitalized for stroke?

Output: HeadPoST

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the large international, cluster-randomized, crossover open-label trial that enrolled any patient hospitalized for stroke?. ### Response: HeadPoST.


Instruction: How long after randomization did the distribution of mRS scores at 90 days do?

Output: 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after randomization did the distribution of mRS scores at 90 days do?. ### Response: 24 hours.


Instruction: What did not differ between the groups after randomization?

Output: Distribution of mRS scores at 90 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not differ between the groups after randomization?. ### Response: Distribution of mRS scores at 90 days.


Instruction: What did patients in the flat-head position group be less often able to maintain for 24 hours?

Output: the assigned head position

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did patients in the flat-head position group be less often able to maintain for 24 hours?. ### Response: the assigned head position.


Instruction: What did not differ between the 2 groups?

Output: Distribution of mRS scores at 90 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not differ between the 2 groups?. ### Response: Distribution of mRS scores at 90 days.


Instruction: What has been criticized because of various limitations?

Output: pragmatic trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been criticized because of various limitations?. ### Response: pragmatic trial.


Instruction: How did HeadPoST enroll patients with minor strokes?

Output: flat-head (0°) or elevated head (≥30°) maintained for 24 hours after randomization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did HeadPoST enroll patients with minor strokes?. ### Response: flat-head (0°) or elevated head (≥30°) maintained for 24 hours after randomization.


Instruction: How long did the initiation of the intervention take?

Output: 14 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the initiation of the intervention take?. ### Response: 14 hours.


Instruction: How long was the median time to initiate the intervention?

Output: 14 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the median time to initiate the intervention?. ### Response: 14 hours.


Instruction: What type of position may have made a difference?

Output: flat-head

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of position may have made a difference?. ### Response: flat-head.


Instruction: What has been shown to improve cerebral perfusion in patients with AIS?

Output: the lying-flat position

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to improve cerebral perfusion in patients with AIS?. ### Response: the lying-flat position.


Instruction: When is the intervention initiated early after stroke onset?

Output: after hospitalization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the intervention initiated early after stroke onset?. ### Response: after hospitalization.


Instruction: What is the focus of the Supplemental Oxygen section?

Output: in-hospital management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the Supplemental Oxygen section?. ### Response: in-hospital management.


Instruction: What is recommended for in-hospital management?

Output: The use of comprehensive specialized stroke care (stroke units) that incorporates rehabilitation is recommended.I ARecommendation unchanged from 2013 AIS Guidelines.2.  The use of standardized stroke care order sets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for in-hospital management?. ### Response: The use of comprehensive specialized stroke care (stroke units) that incorporates rehabilitation is recommended.I ARecommendation unchanged from 2013 AIS Guidelines.2.  The use of standardized stroke care order sets.


Instruction: What are airway support and ventilatory assistance recommended for?

Output: the treatment of patients with acute stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are airway support and ventilatory assistance recommended for?. ### Response: the treatment of patients with acute stroke.


Instruction: What is recommended for patients with acute stroke who have decreased consciousness or who have bulbar dysfunction that causes compromise of the airway?

Output: Airway support and ventilatory assistance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with acute stroke who have decreased consciousness or who have bulbar dysfunction that causes compromise of the airway?. ### Response: Airway support and ventilatory assistance.


Instruction: What should be provided to maintain oxygen saturation >94%?

Output: Supplemental oxygen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be provided to maintain oxygen saturation >94%?. ### Response: Supplemental oxygen.


Instruction: What is responsible for variations in warfarindose adjustment practice?

Output: differences in the qualityof anticoagulation control between centers and countries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is responsible for variations in warfarindose adjustment practice?. ### Response: differences in the qualityof anticoagulation control between centers and countries.


Instruction: What is the effect of regionaldifferences in asia on edoxaban?

Output: ef ﬁcacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of regionaldifferences in asia on edoxaban?. ### Response: ef ﬁcacy and safety.


Instruction: What is responsible for differences in quality of anticoagulation control between centers and countries?

Output: Variation in warfarindose adjustment practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is responsible for differences in quality of anticoagulation control between centers and countries?. ### Response: Variation in warfarindose adjustment practice.


Instruction: What is the name of the RandomizedEvaluation of Long-Term Anticoagulation Therapy trial?

Output: RE-LY

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the RandomizedEvaluation of Long-Term Anticoagulation Therapy trial?. ### Response: RE-LY.


Instruction: What is the difference betweenapixaban and warfarin?

Output: Ef ﬁcacy and safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference betweenapixaban and warfarin?. ### Response: Ef ﬁcacy and safety.


Instruction: What does Circulation 2013 say about the efficacy and safety ofdabigatran?

Output: 2166

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Circulation 2013 say about the efficacy and safety ofdabigatran?. ### Response: 2166.


Instruction: Which drug is used for stroke prevention inatrial fibrillation?

Output: dabigatran

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug is used for stroke prevention inatrial fibrillation?. ### Response: dabigatran.


Instruction: Who is the author of the study?

Output: Chan PH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of the study?. ### Response: Chan PH.


Instruction: What is the difference between dabigatran and warfarin for stroke prevention?

Output: different levels of predictedinternational normalized ratio control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between dabigatran and warfarin for stroke prevention?. ### Response: different levels of predictedinternational normalized ratio control.


Instruction: What was the name of the study that examined the safety of dabigan compared to warfarine?

Output: RE-LY trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that examined the safety of dabigan compared to warfarine?. ### Response: RE-LY trial.


Instruction: When was the RE-LY trial published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the RE-LY trial published?. ### Response: 2012.


Instruction: What is the time to therapeutic range?

Output: TtTR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the time to therapeutic range?. ### Response: TtTR.


Instruction: What does TtTR stand for?

Output: Time to therapeutic range

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does TtTR stand for?. ### Response: Time to therapeutic range.


Instruction: Whose naive patients have atrial fibrillation?

Output: Pastori D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Whose naive patients have atrial fibrillation?. ### Response: Pastori D.


Instruction: What did the Edoxaban Versus Enoxaparin-Warfarin in Patients Undergoing Cardioversion of Atrial Fibrillation Trial include?

Output: Anticoagulation control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Edoxaban Versus Enoxaparin-Warfarin in Patients Undergoing Cardioversion of Atrial Fibrillation Trial include?. ### Response: Anticoagulation control.


Instruction: What is the SAMe-TT(2)R(2) score?

Output: Factors affectingquality of anticoagulation control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the SAMe-TT(2)R(2) score?. ### Response: Factors affectingquality of anticoagulation control.


Instruction: What is used to predict anticoagulation control in atrial fibrillation and venousthromboembolism patients treated with vitamin K antagonists?

Output: SAMe-TT2R2score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used to predict anticoagulation control in atrial fibrillation and venousthromboembolism patients treated with vitamin K antagonists?. ### Response: SAMe-TT2R2score.


Instruction: What is the SAMe-TT2R2score used for?

Output: anticoagulation control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the SAMe-TT2R2score used for?. ### Response: anticoagulation control.


Instruction: What predicts warfarin control in a Singaporean population?

Output: Score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts warfarin control in a Singaporean population?. ### Response: Score.


Instruction: What does the SAMe TT 2R2 score predict?

Output: anticoagulation control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the SAMe TT 2R2 score predict?. ### Response: anticoagulation control.


Instruction: When did the J StrokeCerebrovasc Dis 2017 issue 26(1):64-69?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J StrokeCerebrovasc Dis 2017 issue 26(1):64-69?. ### Response: 2017.


Instruction: What is good anticoagulation control with warfarin in Chinesepatients with atrial fibrillation?

Output: SAMe-TT 2R2score

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is good anticoagulation control with warfarin in Chinesepatients with atrial fibrillation?. ### Response: SAMe-TT 2R2score.


Instruction: What is relationship to ischemic strokeincidence?

Output: Use of the SAMe-TT 2R2score topredict good anticoagulation control with warfarin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is relationship to ischemic strokeincidence?. ### Response: Use of the SAMe-TT 2R2score topredict good anticoagulation control with warfarin.


Instruction: PloS One. 2016;11(3):e0150674.176

Output: Use of the SAMe-TT 2R2score topredict good anticoagulation control with warfarin in Chinesepatients with atrial ﬁbrillation: relationship to ischemic strokeincidence. PloS One . 2016;11(3):e0150674 .176

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: PloS One. 2016;11(3):e0150674.176. ### Response: Use of the SAMe-TT 2R2score topredict good anticoagulation control with warfarin in Chinesepatients with atrial ﬁbrillation: relationship to ischemic strokeincidence. PloS One . 2016;11(3):e0150674 .176.


Instruction: What did the SPARCL trial show?

Output: did not experience an increased risk of stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the SPARCL trial show?. ### Response: did not experience an increased risk of stroke.


Instruction: How many subjects with metabolic syndrome and TIA did not experience an increased risk of stroke?

Output: 642

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many subjects with metabolic syndrome and TIA did not experience an increased risk of stroke?. ### Response: 642.


Instruction: How many studies have used >1 definition of the metabolic syndrome to assess the risk for stroke?

Output: many stud-ies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies have used >1 definition of the metabolic syndrome to assess the risk for stroke?. ### Response: many stud-ies.


Instruction: What definition may prove to be superior in establishing the relationship?

Output: harmonized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What definition may prove to be superior in establishing the relationship?. ### Response: harmonized.


Instruction: There are essentially no trial data that address the effects of treatment on what?

Output: cardiovascular morbidity and mortal-ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are essentially no trial data that address the effects of treatment on what?. ### Response: cardiovascular morbidity and mortal-ity.


Instruction: How many healthy men and women participated in the JUPITER Trial?

Output: 17 802

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many healthy men and women participated in the JUPITER Trial?. ### Response: 17 802.


Instruction: What was the LDL cholesterol level of the participants?

Output: <130 mg/dL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the LDL cholesterol level of the participants?. ### Response: <130 mg/dL.


Instruction: How much rosuvastatin did the participants receive?

Output: 20 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much rosuvastatin did the participants receive?. ### Response: 20 mg daily.


Instruction: What is rosuvastatin 20 mg daily or placebo?

Output: LDL cholesterol levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rosuvastatin 20 mg daily or placebo?. ### Response: LDL cholesterol levels.


Instruction: What was the hazard ratio?

Output: 0.56

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the hazard ratio?. ### Response: 0.56.


Instruction: What was the hazard ratio for the primary end point?

Output: 0.56

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the hazard ratio for the primary end point?. ### Response: 0.56.


Instruction: How many patients were included in the TNT study with clinically evident coronary heart disease?

Output: 10 001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were included in the TNT study with clinically evident coronary heart disease?. ### Response: 10 001.


Instruction: What is the risk ratio for MI?

Output: 0.46

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk ratio for MI?. ### Response: 0.46.


Instruction: Who had similar reductions in CVD events?

Output: Patients with or without the metabolic syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who had similar reductions in CVD events?. ### Response: Patients with or without the metabolic syndrome.


Instruction: How many patients were included in the TNT study?

Output: 10 001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were included in the TNT study?. ### Response: 10 001.


Instruction: What is the LDL cholesterol substantially 100 mg/dL?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the LDL cholesterol substantially 100 mg/dL?. ### Response: <.


Instruction: What is a multilevel analysis of patients in ASSENT-2?

Output: International differences in in-hospital revascularization and outcomes following acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a multilevel analysis of patients in ASSENT-2?. ### Response: International differences in in-hospital revascularization and outcomes following acute myocardial infarction.


Instruction: What is the name of the intervention used for late reperfusion after myocardial infarction?

Output: Percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the intervention used for late reperfusion after myocardial infarction?. ### Response: Percutaneous coronary intervention.


Instruction: What is the name of the randomized multi-centre trial of oc-cluded artery angioplasty after acute myocardial infarction?

Output: DECOPI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized multi-centre trial of oc-cluded artery angioplasty after acute myocardial infarction?. ### Response: DECOPI.


Instruction: What is DECOPI?

Output: DEsobstruction COronaire en Post-Infarctus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DECOPI?. ### Response: DEsobstruction COronaire en Post-Infarctus.


Instruction: Infarct artery reocclusion after primary angioplasty, stent placement, and thrombolytic therapy for acute myocardial infarction.

Output: Wilson SH, Bell MR, Rihal CS, et al. Infarct artery reocclusion after primary angioplasty, stent placement, and thrombolytic therapy for acute myocardial infarction. Am Heart J. 2001;141:704–10.379

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Infarct artery reocclusion after primary angioplasty, stent placement, and thrombolytic therapy for acute myocardial infarction.. ### Response: Wilson SH, Bell MR, Rihal CS, et al. Infarct artery reocclusion after primary angioplasty, stent placement, and thrombolytic therapy for acute myocardial infarction. Am Heart J. 2001;141:704–10.379.


Instruction: Am Heart J. 2001;141:704–10.379.

Output: Infarct artery reocclusion after primary angioplasty, stent placement, and thrombolytic therapy for acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Am Heart J. 2001;141:704–10.379.. ### Response: Infarct artery reocclusion after primary angioplasty, stent placement, and thrombolytic therapy for acute myocardial infarction.


Instruction: Early revascularization and long-term survival in cardiogenic shock complicate what?

Output: acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Early revascularization and long-term survival in cardiogenic shock complicate what?. ### Response: acute myocardial infarction.


Instruction: What complicates acute myocardial infarction?

Output: Early revascularization and long-term survival in cardiogenic shock

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What complicates acute myocardial infarction?. ### Response: Early revascularization and long-term survival in cardiogenic shock.


Instruction: When did JAMA publish 295:2511–5.380?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA publish 295:2511–5.380?. ### Response: 2006.


Instruction: How long did per-cutaneous coronary intervention of the totally occluded infarct-related artery in the subacute phase?

Output: Long-term effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did per-cutaneous coronary intervention of the totally occluded infarct-related artery in the subacute phase?. ### Response: Long-term effects.


Instruction: What year did Circulation. 2011;124:2320–8.381.

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circulation. 2011;124:2320–8.381.. ### Response: 2011.


Instruction: What is the name of the study group that studies thrombolysis and angioplasty in myocardial infarction?

Output: TAMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study group that studies thrombolysis and angioplasty in myocardial infarction?. ### Response: TAMI.


Instruction: What is the name of the TAMI Study Group?

Output: Thrombolysis and Angioplasty in Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the TAMI Study Group?. ### Response: Thrombolysis and Angioplasty in Myocardial Infarction.


Instruction: What is a key predictor of short-term prognosis after reperfusion therapy for acute myocardial infarction?

Output: Multivessel coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a key predictor of short-term prognosis after reperfusion therapy for acute myocardial infarction?. ### Response: Multivessel coronary artery disease.


Instruction: What type of intervention is used in patients with multivessel disease and acute myocardial infarction?

Output: Multivessel percutaneous coro-nary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention is used in patients with multivessel disease and acute myocardial infarction?. ### Response: Multivessel percutaneous coro-nary intervention.


Instruction: When was the Am Heart J.148:493–500.384?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am Heart J.148:493–500.384?. ### Response: 2004.


Instruction: What is the management of multives-sel coronary disease after primary angioplasty?

Output: Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the management of multives-sel coronary disease after primary angioplasty?. ### Response: Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade.


Instruction: What is the name of the platelet glycoprotein IIb/IIIa inhibitor used in thrombolysis?

Output: lamifiban

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the platelet glycoprotein IIb/IIIa inhibitor used in thrombolysis?. ### Response: lamifiban.


Instruction: What is lamifiban?

Output: platelet glycoprotein IIb/IIIa inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lamifiban?. ### Response: platelet glycoprotein IIb/IIIa inhibitor.


Instruction: What is the name of the PARA-DIGM trial?

Output: Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PARA-DIGM trial?. ### Response: Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction.


Instruction: In what year did the J Am Coll Cardiol issue 32:2003-10.387?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did the J Am Coll Cardiol issue 32:2003-10.387?. ### Response: 1998.


Instruction: What type of integrin receptor blockade is used in acute myocardial infarction?

Output: platelet glycoprotein IIb/IIIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of integrin receptor blockade is used in acute myocardial infarction?. ### Response: platelet glycoprotein IIb/IIIa.


Instruction: What is the name of the randomized, placebo-controlled, dose-ranging trial?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, placebo-controlled, dose-ranging trial?. ### Response: Circulation.


Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?

Output: 2014 VA/DoD HTN CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Diagnosis and Management of Hypertension in the Primary Care Setting?. ### Response: 2014 VA/DoD HTN CPG.


Instruction: What does the 2020 Strength of Recommendation Recomendation Category 1 recommend?

Output: screening adults for elevated blood pressure periodically

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the 2020 Strength of Recommendation Recomendation Category 1 recommend?. ### Response: screening adults for elevated blood pressure periodically.


Instruction: We recommend screening adults for elevated blood pressure periodically.

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: We recommend screening adults for elevated blood pressure periodically.. ### Response: 1.


Instruction: What do we suggest using?

Output: atte nded or unattended, fully automated office blood pressure measurement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest using?. ### Response: atte nded or unattended, fully automated office blood pressure measurement.


Instruction: How long does it take to take a blood pressure measurement?

Output: five minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to take a blood pressure measurement?. ### Response: five minutes.


Instruction: How long is the time it takes to take an office blood pressure measure?

Output: five minutes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is the time it takes to take an office blood pressure measure?. ### Response: five minutes.


Instruction: What is a weak for reviewed, new-added reference?

Output: Weak

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a weak for reviewed, new-added reference?. ### Response: Weak.


Instruction: What do we suggest when fully automated blood pressure measurement is not available?

Output: measurement of blood pressure using standard technique and a properly calibrated and validated sphygmomanometer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest when fully automated blood pressure measurement is not available?. ### Response: measurement of blood pressure using standard technique and a properly calibrated and validated sphygmomanometer.


Instruction: What technique should be used when measuring blood pressure?

Output: standard technique

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What technique should be used when measuring blood pressure?. ### Response: standard technique.


Instruction: How is blood pressure measured?

Output: using standard technique and a properly calibrated and validated sphygmomanometer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is blood pressure measured?. ### Response: using standard technique and a properly calibrated and validated sphygmomanometer.


Instruction: What do we suggest using out-of-office blood pressure monitoring methods to inform the diagnosis and management of hypertension?

Output: ambulatory 24-hour  monitoring or home blood pressure measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do we suggest using out-of-office blood pressure monitoring methods to inform the diagnosis and management of hypertension?. ### Response: ambulatory 24-hour  monitoring or home blood pressure measurements.


Instruction: What does home blood pressure self -monitoring with co -interventions do for lowering systolic blood pressure?

Output: Among patie nts treated for hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does home blood pressure self -monitoring with co -interventions do for lowering systolic blood pressure?. ### Response: Among patie nts treated for hypertension.


Instruction: What is a weak for review, new -replaced 5?

Output: Weak

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a weak for review, new -replaced 5?. ### Response: Weak.


Instruction: What type of review was weak for review, new-added?

Output: Reviewed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of review was weak for review, new-added?. ### Response: Reviewed.


Instruction: What section of the Grading Recomme ndations section provides more information on how the strength of a recommendation is calculated?

Output: GRADE methodology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section of the Grading Recomme ndations section provides more information on how the strength of a recommendation is calculated?. ### Response: GRADE methodology.


Instruction: How was the strength of a recommendation determined using GRADE methodology?

Output: Strength of Recommendation columns: Refer to the  Grading Recomme ndations  section

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the strength of a recommendation determined using GRADE methodology?. ### Response: Strength of Recommendation columns: Refer to the  Grading Recomme ndations  section.


Instruction: What is the first set of references listed in each row in the evidence column?

Output: the evidence base for the recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first set of references listed in each row in the evidence column?. ### Response: the evidence base for the recommendation.


Instruction: What did VA/DoD need to identify to be included in the evidence base for a recommendation?

Output: a reference

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did VA/DoD need to identify to be included in the evidence base for a recommendation?. ### Response: a reference.


Instruction: What was the second set of references in the guideline update?

Output: Additional References

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the second set of references in the guideline update?. ### Response: Additional References.


Instruction: What is the second set of references in the evidence column called?

Output: Additional References

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the second set of references in the evidence column called?. ### Response: Additional References.


Instruction: What are the references that provide additional informa tion related to the recommendation not systematically identified through?

Output: a literature review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the references that provide additional informa tion related to the recommendation not systematically identified through?. ### Response: a literature review.


Instruction: What was not included in the evidence base for the recommendation and therefore did not influence the strength and direction of the recommendation?

Output: references that provide additional informa tion related to the recommendation, but which were not systematically identified through a literature review. These references

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not included in the evidence base for the recommendation and therefore did not influence the strength and direction of the recommendation?. ### Response: references that provide additional informa tion related to the recommendation, but which were not systematically identified through a literature review. These references.


Instruction: Refer to the Recommendation Categorization section for more information on the description of what?

Output: the categorization process

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Refer to the Recommendation Categorization section for more information on the description of what?. ### Response: the categorization process.


Instruction: What is the description of the categorization process and the definition of each category?

Output: Recommendatio n Categorization  section

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the description of the categorization process and the definition of each category?. ### Response: Recommendatio n Categorization  section.


Instruction: What is the name of the meta-anal-ysis of controlled studies?

Output: Efficacy and safety of anticoagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-anal-ysis of controlled studies?. ### Response: Efficacy and safety of anticoagulants.


Instruction: What is Efficacy and safety of anticoagulants in the prevention of?

Output: venous throm-boembolism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Efficacy and safety of anticoagulants in the prevention of?. ### Response: venous throm-boembolism.


Instruction: What type of filter placement is recommended for patients with primary intracerebral hemorrhage developing venous thromboembolism?

Output: Anticoagulation or inferior vena cava

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of filter placement is recommended for patients with primary intracerebral hemorrhage developing venous thromboembolism?. ### Response: Anticoagulation or inferior vena cava.


Instruction: What year did Stroke. 2003:34:2999–305. doi: 10.1161/01.STR.0000102561.86835.17. Available from http://ahajournals.org by when?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Stroke. 2003:34:2999–305. doi: 10.1161/01.STR.0000102561.86835.17. Available from http://ahajournals.org by when?. ### Response: April 28, 2023.


Instruction: What is the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition in the progression of chronic Kidney disease?

Output: a patient-level meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition in the progression of chronic Kidney disease?. ### Response: a patient-level meta-analysis.


Instruction: When did the Ann Intern Med issue 139:244-52?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Ann Intern Med issue 139:244-52?. ### Response: 2003.


Instruction: What did Law MR, Morris JK, Wald NJ, and Wald NJ study?

Output: meta-analysis of 147 randomised trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Law MR, Morris JK, Wald NJ, and Wald NJ study?. ### Response: meta-analysis of 147 randomised trials.


Instruction: How many randomised trials were included in the meta-analysis of 147 trials?

Output: 147

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many randomised trials were included in the meta-analysis of 147 trials?. ### Response: 147.


Instruction: What is the name of the study that analyzed 147 randomised studies in the context of expectations from prospective epidemiological studies?

Output: INDANA Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that analyzed 147 randomised studies in the context of expectations from prospective epidemiological studies?. ### Response: INDANA Investigators.


Instruction: When was the BMJ 338 published?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the BMJ 338 published?. ### Response: 2009.


Instruction: What year did the American Heart Association publish a report on heart disease and stroke statistics?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the American Heart Association publish a report on heart disease and stroke statistics?. ### Response: 2017.


Instruction: What is the name of the organization that published the 2017 update?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that published the 2017 update?. ### Response: American Heart Association.


Instruction: How did the INDANA Investigators study the effect of antihypertensive drug treatment on cardiovascular outcomes?

Output: A meta-analysis of individual patient data from randomized, controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the INDANA Investigators study the effect of antihypertensive drug treatment on cardiovascular outcomes?. ### Response: A meta-analysis of individual patient data from randomized, controlled trials.


Instruction: What is the name of the INDANA Investigators?

Output: Turnbull F, Woodward M, Neal B, et al. Do men and women respond differently to blood pressure-lowering treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the INDANA Investigators?. ### Response: Turnbull F, Woodward M, Neal B, et al. Do men and women respond differently to blood pressure-lowering treatment.


Instruction: When was the Ann Intern Med 126:761–7?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Ann Intern Med 126:761–7?. ### Response: 1997.


Instruction: What are the results of prospectively designed overviews of randomized trials?

Output: Do men and women respond differently to blood pressure-lowering treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of prospectively designed overviews of randomized trials?. ### Response: Do men and women respond differently to blood pressure-lowering treatment.


Instruction: What does Eur Heart J. 2008:29:2669-80.10.2.1. Women S10.2.1-1. Turnbull F, Woodward M, Neal B, et al. Do men and women respond differently to blood pressure-lowering treatment?

Output: Results of prospectively designed overviews of randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Eur Heart J. 2008:29:2669-80.10.2.1. Women S10.2.1-1. Turnbull F, Woodward M, Neal B, et al. Do men and women respond differently to blood pressure-lowering treatment?. ### Response: Results of prospectively designed overviews of randomized trials.


Instruction: What is associated with increased survival in male but not female hypertensive patients?

Output: Beta adrenoceptor block-ade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with increased survival in male but not female hypertensive patients?. ### Response: Beta adrenoceptor block-ade.


Instruction: What is adrenoceptor block-ade associated with?

Output: increased survival in male but not female hypertensive patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is adrenoceptor block-ade associated with?. ### Response: increased survival in male but not female hypertensive patients.


Instruction: What is the DHCCP?

Output: DHSS Hypertension Care Computing Project

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DHCCP?. ### Response: DHSS Hypertension Care Computing Project.


Instruction: When was the J Hum Hypertens 2:219–27?

Output: 1988

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Hum Hypertens 2:219–27?. ### Response: 1988.


Instruction: What was the BMJ OPEN 2014:4:e004812.

Output: General practitioners' use of absolute risk versus individual risk factors in cardiovas-cular disease prevention: an experimental study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the BMJ OPEN 2014:4:e004812.. ### Response: General practitioners' use of absolute risk versus individual risk factors in cardiovas-cular disease prevention: an experimental study.


Instruction: What is the name of the study?

Output: INDANA Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: INDANA Investigators.


Instruction: What is a stage 1 diastolic hypertension?

Output: antihypertensive treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a stage 1 diastolic hypertension?. ### Response: antihypertensive treatment.