Instruction: Why is the recommendation strong?

Output: the potential prevention of transplant failure outweighs potentialrisks of burden associated with its implementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the recommendation strong?. ### Response: the potential prevention of transplant failure outweighs potentialrisks of burden associated with its implementation.


Instruction: What outweighs the potential risks of burden associated with its implementation?

Output: the potential prevention of transplant failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What outweighs the potential risks of burden associated with its implementation?. ### Response: the potential prevention of transplant failure.


Instruction: The Work Group judged that all or nearly all well-informed transplantpatients would choose to receive what?

Output: a CCB or an ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The Work Group judged that all or nearly all well-informed transplantpatients would choose to receive what?. ### Response: a CCB or an ARB.


Instruction: What is an ARB given thepotential bene fit?

Output: CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an ARB given thepotential bene fit?. ### Response: CCB.


Instruction: What is the importance of preventing graft loss to?

Output: kidneytransplant recipients and clinicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the importance of preventing graft loss to?. ### Response: kidneytransplant recipients and clinicians.


Instruction: What may be reasonable in severely obese patients with the goal of weight stabilization or reduc-tion?

Output: caloric restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable in severely obese patients with the goal of weight stabilization or reduc-tion?. ### Response: caloric restriction.


Instruction: What can be reasonable for patients with HF with a BMI >35 kg/m2?

Output: gastrointestinal surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be reasonable for patients with HF with a BMI >35 kg/m2?. ### Response: gastrointestinal surgery.


Instruction: What may be an option for patients with HF with a BMI >35 kg/m2?

Output: gastrointestinal surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be an option for patients with HF with a BMI >35 kg/m2?. ### Response: gastrointestinal surgery.


Instruction: In patients with diabetes mellitus, dyslipidemia, or severe obesity, specific dietary instructions are recommended (Level of Evidence B).

Output: obesity in p atients at risk for or With Established HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with diabetes mellitus, dyslipidemia, or severe obesity, specific dietary instructions are recommended (Level of Evidence B).. ### Response: obesity in p atients at risk for or With Established HF.


Instruction: What should be controlled or avoided to prevent the development of HF along with other CVDs?

Output: Obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be controlled or avoided to prevent the development of HF along with other CVDs?. ### Response: Obesity.


Instruction: What are the stages B and C HF1?

Output: Stage A HF1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the stages B and C HF1?. ### Response: Stage A HF1.


Instruction: What may be reasonable in obese patients with HF?

Output: caloric restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable in obese patients with HF?. ### Response: caloric restriction.


Instruction: What is the class of HF in obese patients?

Output: Class IIb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the class of HF in obese patients?. ### Response: Class IIb.


Instruction: What type of weight loss preparations are contraindicated in HF?

Output: Sibutramine or ephedra

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of weight loss preparations are contraindicated in HF?. ### Response: Sibutramine or ephedra.


Instruction: Who should avoid using ephedra weight-loss preparations?

Output: obese patients with HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should avoid using ephedra weight-loss preparations?. ### Response: obese patients with HF.


Instruction: What has not been proven to reduce the incidence or severity of HF or mortality in HF?

Output: Weight reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been proven to reduce the incidence or severity of HF or mortality in HF?. ### Response: Weight reduction.


Instruction: What is an example of a weight-loss drug?

Output: orlistat

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a weight-loss drug?. ### Response: orlistat.


Instruction: Hypercholesterolemia has been shown to be associated with what?

Output: worse outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hypercholesterolemia has been shown to be associated with what?. ### Response: worse outcomes.


Instruction: In patients with atheroscle-rotic CVD, what has been associated with worse outcomes?

Output: hypercholesterolemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with atheroscle-rotic CVD, what has been associated with worse outcomes?. ### Response: hypercholesterolemia.


Instruction: What has been shown to be independently associated with increased mortality and higher cholesterol levels with improved survival?

Output: low cholesterol levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been shown to be independently associated with increased mortality and higher cholesterol levels with improved survival?. ### Response: low cholesterol levels.


Instruction: In pa-tients with chronic HF, this inverse relationship has been demonstrated in patients with what?

Output: HF of ischemic and non-ischemic origin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In pa-tients with chronic HF, this inverse relationship has been demonstrated in patients with what?. ### Response: HF of ischemic and non-ischemic origin.


Instruction: What has been demonstrated in patients with HF of ischemic and non-ischemic origin with a cutoff for total cholesterol at 190 to 200 mg/dL?

Output: inverse relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been demonstrated in patients with HF of ischemic and non-ischemic origin with a cutoff for total cholesterol at 190 to 200 mg/dL?. ### Response: inverse relationship.


Instruction: What is currently unclear whether low cholesterol or high cholesterol holds true?

Output: low cholesterol levels play a causative role in the worse out-come of patients with HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is currently unclear whether low cholesterol or high cholesterol holds true?. ### Response: low cholesterol levels play a causative role in the worse out-come of patients with HF.


Instruction: Is there a difference between intrinsically low cholesterol and low cholesterol?

Output: whether there is a difference between intrinsically low cholesterol and low cholesterol as a re-sult of treatment remains unanswered

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is there a difference between intrinsically low cholesterol and low cholesterol?. ### Response: whether there is a difference between intrinsically low cholesterol and low cholesterol as a re-sult of treatment remains unanswered.


Instruction: Does low cholesterol play a role in the worse out-come of HF patients?

Output: It is currently unclear whether low cholesterol levels play a causative role

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Does low cholesterol play a role in the worse out-come of HF patients?. ### Response: It is currently unclear whether low cholesterol levels play a causative role.


Instruction: What remains unanswered as a result of treatment?

Output: the question of whether there is a difference between intrinsically low cholesterol and low cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains unanswered as a result of treatment?. ### Response: the question of whether there is a difference between intrinsically low cholesterol and low cholesterol.


Instruction: What type of hypertension is a risk factor for SIHD?

Output: exertional

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hypertension is a risk factor for SIHD?. ### Response: exertional.


Instruction: What are patients with SIHD who have accelerating symptoms ordecreasing functional capacity required to do?

Output: prompt reassessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with SIHD who have accelerating symptoms ordecreasing functional capacity required to do?. ### Response: prompt reassessment.


Instruction: Who should be evaluated and treated according to establishedguidelines?

Output: Patients with SIHD who develop new ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should be evaluated and treated according to establishedguidelines?. ### Response: Patients with SIHD who develop new ACS.


Instruction: What should new ACS be evaluated and treated according to?

Output: establishedguidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should new ACS be evaluated and treated according to?. ### Response: establishedguidelines.


Instruction: What should patients who have been treated for an ACSe426 Circulation December 18/25, 2012Downloaded from http://ahajournals.org by on May 1, 2023?

Output: Patients with SIHD who develop new ACS shouldbe evaluated and treated according to establishedguidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients who have been treated for an ACSe426 Circulation December 18/25, 2012Downloaded from http://ahajournals.org by on May 1, 2023?. ### Response: Patients with SIHD who develop new ACS shouldbe evaluated and treated according to establishedguidelines.


Instruction: What is the name of the Task Force to Revise the 2007 Clinical Competence Statement onCardiac Interventional Procedures?

Output: WritingCommittee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force to Revise the 2007 Clinical Competence Statement onCardiac Interventional Procedures?. ### Response: WritingCommittee.


Instruction: What year was the 2007 Clinical Competence Statement onCardiac Interventional Procedures revised?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the 2007 Clinical Competence Statement onCardiac Interventional Procedures revised?. ### Response: 2013.


Instruction: What year did the Dartmouth Institute for Health Policy and Clinical Practice publish a report on improving patient decision making in health care?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Dartmouth Institute for Health Policy and Clinical Practice publish a report on improving patient decision making in health care?. ### Response: 2011.


Instruction: What is the name of the 2011 Dartmouth Atlas ReportHighlighting Minnesota?

Output: Improving PatientDecision-Making in Health Care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2011 Dartmouth Atlas ReportHighlighting Minnesota?. ### Response: Improving PatientDecision-Making in Health Care.


Instruction: Where is the 2011 report available?

Output: J AmColl Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the 2011 report available?. ### Response: J AmColl Cardiol.


Instruction: When was the report available for download?

Output: October 11, 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the report available for download?. ### Response: October 11, 2013.


Instruction: What year did the report come out?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the report come out?. ### Response: 2011.


Instruction: What is the name of the organization that uses measurement to promote quality improvement?

Output: Accountability measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that uses measurement to promote quality improvement?. ### Response: Accountability measures.


Instruction: What is a classi-fication of care metrics?

Output: performance measures and quality metrics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a classi-fication of care metrics?. ### Response: performance measures and quality metrics.


Instruction: What is the name of the Task Force on Performance Measures?

Output: American College of Cardiology/American HeartAssociation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Performance Measures?. ### Response: American College of Cardiology/American HeartAssociation.


Instruction: When was the J Am Coll Car-diol 52:2113– 7.29?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Car-diol 52:2113– 7.29?. ### Response: 2008.


Instruction: What is therapy in patients with coronaryartery stents?

Output: dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is therapy in patients with coronaryartery stents?. ### Response: dual antiplatelet therapy.


Instruction: What is a science advisory from the American Heart Association,American College of Cardiology, Society for Cardiovascular Angio-ography and Interventions, American College of Surgeons, and American Dental Association?

Output: Prevention of prematurediscontinuation of dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a science advisory from the American Heart Association,American College of Cardiology, Society for Cardiovascular Angio-ography and Interventions, American College of Surgeons, and American Dental Association?. ### Response: Prevention of prematurediscontinuation of dual antiplatelet therapy.


Instruction: What is the effect of drug-elutingstents on thrombosis?

Output: Incidence, predictors, andoutcome of thrombosis after successful implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of drug-elutingstents on thrombosis?. ### Response: Incidence, predictors, andoutcome of thrombosis after successful implantation.


Instruction: When did JAMA issue 293:2126–30.31?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 293:2126–30.31?. ### Response: 2005.


Instruction: What is important for classi fication of chronic kidney disease?

Output: glomerularﬁltration rate formula

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important for classi fication of chronic kidney disease?. ### Response: glomerularﬁltration rate formula.


Instruction: What is the glomerularfiltration rate formula used for?

Output: classi ﬁcation of chronic kidney disease inpatients with non-ST-segment elevation acute coronary syndromes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the glomerularfiltration rate formula used for?. ### Response: classi ﬁcation of chronic kidney disease inpatients with non-ST-segment elevation acute coronary syndromes.


Instruction: What are patients with non-ST-segment elevation acute coronary syndromes with?

Output: chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with non-ST-segment elevation acute coronary syndromes with?. ### Response: chronic kidney disease.


Instruction: What are contrast mediain patients undergoing?

Output: percutaneous coronary interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are contrast mediain patients undergoing?. ### Response: percutaneous coronary interventions.


Instruction: What are recommendations for the high riskpatientundergoing cardiovascular procedures?

Output: Prevention ofcontrast induced nephropathy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are recommendations for the high riskpatientundergoing cardiovascular procedures?. ### Response: Prevention ofcontrast induced nephropathy.


Instruction: What year is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction?

Output: 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction?. ### Response: 2020.


Instruction: What is the P age 106 of 127 B?

Output: VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the P age 106 of 127 B?. ### Response: VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020.


Instruction: Question 1 – Time to repeat screening for CV risk?

Output: VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Question 1 – Time to repeat screening for CV risk?. ### Response: VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction.


Instruction: Question 2 and 3 include specific terms for what?

Output: CV risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Question 2 and 3 include specific terms for what?. ### Response: CV risk.


Instruction: #1 Dyslipidemia exp dyslipidemias/ OR exp cholesterol/ OR what else?

Output: lipids

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: #1 Dyslipidemia exp dyslipidemias/ OR exp cholesterol/ OR what else?. ### Response: lipids.


Instruction: Hyperlipoproteinaemia* OR hypertriglyceridemia * OR hyperlipaemia OR cholesteryl* OR cholesterol* OR lipid* OR lipoprotein* OR tryglycer* OR triaclyglycerol* OR "HDL -C" OR "LDL-C") OR what else?

Output: cholesterol* OR lipid* OR lipoprotein* OR tryglycer* OR triaclyglycer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyperlipoproteinaemia* OR hypertriglyceridemia * OR hyperlipaemia OR cholesteryl* OR cholesterol* OR lipid* OR lipoprotein* OR tryglycer* OR triaclyglycerol* OR "HDL -C" OR "LDL-C") OR what else?. ### Response: cholesterol* OR lipid* OR lipoprotein* OR tryglycer* OR triaclyglycer.


Instruction: What is another name for "HDL -C" OR "LDL C"?

Output: triaclyglycer*

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for "HDL -C" OR "LDL C"?. ### Response: triaclyglycer*.


Instruction: What does ADJ4 mean?

Output: test* or screen* OR assess*

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ADJ4 mean?. ### Response: test* or screen* OR assess*.


Instruction: What is another word for define or defining or predict or prediction or assess?

Output: ADJ4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another word for define or defining or predict or prediction or assess?. ### Response: ADJ4.


Instruction: What is the other word for classif or prioritiz or category?

Output: ADJ4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the other word for classif or prioritiz or category?. ### Response: ADJ4.


Instruction: What type of ADJ2 risk is #3 Repeat s creening/ monitoring Exp time factors/ OR Monitoring, Physiologic/ OR (rescreen* OR re -screen* Or surveillance OR what else?

Output: cardiovascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of ADJ2 risk is #3 Repeat s creening/ monitoring Exp time factors/ OR Monitoring, Physiologic/ OR (rescreen* OR re -screen* Or surveillance OR what else?. ### Response: cardiovascular.


Instruction: Repeat or repet* or replicat* or redo or "re-run" or subsequent* or redundant* or rerun or what else)

Output: "re -do

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Repeat or repet* or replicat* or redo or "re-run" or subsequent* or redundant* or rerun or what else). ### Response: "re -do.


Instruction: What does ADJ4 (test* or screen* OR assess*) do?

Output: define or defining or predict or prediction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ADJ4 (test* or screen* OR assess*) do?. ### Response: define or defining or predict or prediction.


Instruction: What is one of the outcomes of rerun or re-run?

Output: repeat or repet* or replicat* or redo or "re -do

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the outcomes of rerun or re-run?. ### Response: repeat or repet* or replicat* or redo or "re -do.


Instruction: What type of infarction is associated with a stroke?

Output: myocardial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of infarction is associated with a stroke?. ### Response: myocardial.


Instruction: What is a common cause of death associated with an ADJ attack?

Output: heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of death associated with an ADJ attack?. ### Response: heart.


Instruction: What is another word for heart ADJ infarct?

Output: myocardial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another word for heart ADJ infarct?. ### Response: myocardial.


Instruction: What is a word for secondary ADJ prevention?

Output: OR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a word for secondary ADJ prevention?. ### Response: OR.


Instruction: What is the limit to RCTs/SRs/Meta -analysis hedge?

Output: #6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the limit to RCTs/SRs/Meta -analysis hedge?. ### Response: #6.


Instruction: What are the limits to additional study designs?

Output: #7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the limits to additional study designs?. ### Response: #7.


Instruction: What is another term for retrospective studies?

Output: exp

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for retrospective studies?. ### Response: exp.


Instruction: What is a term for cross-over studies or crossover procedure?

Output: OR cross -over studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for cross-over studies or crossover procedure?. ### Response: OR cross -over studies.


Instruction: Which study is an example of a cross over study?

Output: observational study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which study is an example of a cross over study?. ### Response: observational study.


Instruction: What type of studies/ OR exp case -control studies/OR follow -up studies?

Output: validation studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of studies/ OR exp case -control studies/OR follow -up studies?. ### Response: validation studies.


Instruction: How many sets do you combine?

Output: #5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many sets do you combine?. ### Response: #5.


Instruction: What does Kidney International do?

Output: perform physical activity regularly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Kidney International do?. ### Response: perform physical activity regularly.


Instruction: What is the name of the organization that helps patients in whomchapter 2?

Output: kidney-international

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that helps patients in whomchapter 2?. ### Response: kidney-international.


Instruction: What is the effect of an-tihypertensive treatment on left ventricular remodeling and diastolic function?

Output: improved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of an-tihypertensive treatment on left ventricular remodeling and diastolic function?. ### Response: improved.


Instruction: What does improved diastolic function do?

Output: An-tihypertensive treatment in hypertensive patients with normal left ventricular mass is associated with left ventricular remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does improved diastolic function do?. ### Response: An-tihypertensive treatment in hypertensive patients with normal left ventricular mass is associated with left ventricular remodeling.


Instruction: What is the association between blood pressure and mortality in patients with heart failure?

Output: a complex relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between blood pressure and mortality in patients with heart failure?. ### Response: a complex relationship.


Instruction: What is the name of the organization that investigates and coordinates systolic blood pressure at admission?

Output: OPTI-MIZE-HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the organization that investigates and coordinates systolic blood pressure at admission?. ### Response: OPTI-MIZE-HF.


Instruction: What are the clinical characteristics and outcomes in patients hospitalized with acute heart failure?

Output: Systolic blood pressure at admission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinical characteristics and outcomes in patients hospitalized with acute heart failure?. ### Response: Systolic blood pressure at admission.


Instruction: When did JAMA issue 296:2217-2226?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did JAMA issue 296:2217-2226?. ### Response: 2006.


Instruction: Who is the ADHERE Scientific Advisory Committee, Study Group, and Inves-tigators?

Output: Fonarow GC, Adams KF Jr, Abraham WT, Yancy CW, Boscardin WJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the ADHERE Scientific Advisory Committee, Study Group, and Inves-tigators?. ### Response: Fonarow GC, Adams KF Jr, Abraham WT, Yancy CW, Boscardin WJ.


Instruction: What is the risk stratification for in-hospital mortality in acute de-compensated heart failure: classification and regression tree anal-ysis?

Output: 88

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk stratification for in-hospital mortality in acute de-compensated heart failure: classification and regression tree anal-ysis?. ### Response: 88.


Instruction: What are important predictors of 4-week mortality in severe acute heart failure?

Output: Ejection fraction and blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are important predictors of 4-week mortality in severe acute heart failure?. ### Response: Ejection fraction and blood pressure.


Instruction: Ejection fraction and blood pressure are important and what?

Output: interactive predictors of 4-week mortality in severe acute heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ejection fraction and blood pressure are important and what?. ### Response: interactive predictors of 4-week mortality in severe acute heart failure.


Instruction: What is the doi: 10.1016/j.ejheart.2007.06.001?

Output: Eur J Heart Fail

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1016/j.ejheart.2007.06.001?. ### Response: Eur J Heart Fail.


Instruction: What is OPTIMIZE-HF Investigators and Coordinators?

Output: Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is OPTIMIZE-HF Investigators and Coordinators?. ### Response: Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure.


Instruction: What is the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure?

Output: OPTIMIZE-HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure?. ### Response: OPTIMIZE-HF.


Instruction: What does OPTIMIZE-HF stand for?

Output: Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does OPTIMIZE-HF stand for?. ### Response: Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure.


Instruction: What is the J Am Coll Cardiol. 2008:52:347–356?

Output: Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2008:52:347–356?. ### Response: Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure.


Instruction: How does higher systolic blood pressure affect mortality?

Output: para-doxical effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does higher systolic blood pressure affect mortality?. ### Response: para-doxical effect.


Instruction: What does higher systolic blood pressure have on mortality in chronic heart failure?

Output: para-doxical effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does higher systolic blood pressure have on mortality in chronic heart failure?. ### Response: para-doxical effect.


Instruction: What is the doi: 10.1136/hrt.2007.134973?

Output: 91. Raphael CE, Whinnett ZI, Davies JE, Fontana M, Ferenczi EA, Manisty CH, Mayet J, Francis DP. Quantifying the para-doxical effect of higher systolic blood pressure on mortality in chronic heart failure. Heart. 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1136/hrt.2007.134973?. ### Response: 91. Raphael CE, Whinnett ZI, Davies JE, Fontana M, Ferenczi EA, Manisty CH, Mayet J, Francis DP. Quantifying the para-doxical effect of higher systolic blood pressure on mortality in chronic heart failure. Heart. 2009.


Instruction: What does reduced ejection fraction do in patients with heart failure?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does reduced ejection fraction do in patients with heart failure?. ### Response: mortality.


Instruction: What does systolic blood pressure have a different prognostic effect on?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does systolic blood pressure have a different prognostic effect on?. ### Response: mortality.


Instruction: What is the effect of systolic blood pressure on mortality in patients with acute heart failure?

Output: Differential prognostic effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of systolic blood pressure on mortality in patients with acute heart failure?. ### Response: Differential prognostic effect.


Instruction: When did Eur J Heart Fail issue 12:38-44?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur J Heart Fail issue 12:38-44?. ### Response: 2010.


Instruction: What was 42CO-GENT lacking?

Output: more controlled, randomized clinical trial data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was 42CO-GENT lacking?. ### Response: more controlled, randomized clinical trial data.


Instruction: What is needed to address the clinical impact of conjunctive therapy with clopidogrel and PPIs?

Output: more controlled, randomized clinical trial data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to address the clinical impact of conjunctive therapy with clopidogrel and PPIs?. ### Response: more controlled, randomized clinical trial data.


Instruction: What should aPPI include in patients taking clopidogrel?

Output: omeprazole

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should aPPI include in patients taking clopidogrel?. ### Response: omeprazole.


Instruction: What does theFDA note there is no evidence that other drugs that reducestomach acid interfere with?

Output: theantiplatelet activity of clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does theFDA note there is no evidence that other drugs that reducestomach acid interfere with?. ### Response: theantiplatelet activity of clopidogrel.


Instruction: What should healthcare providers continue to prescribe and patients should continue to take as directed?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should healthcare providers continue to prescribe and patients should continue to take as directed?. ### Response: clopidogrel.


Instruction: What has demonstratedbenefits in preventing blood clots that could lead to a heart attack or stroke?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has demonstratedbenefits in preventing blood clots that could lead to a heart attack or stroke?. ### Response: clopidogrel.


Instruction: What is omepra-zole?

Output: over the counter

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is omepra-zole?. ### Response: over the counter.


Instruction: What should patients taking clopidogrel consult their healthcare provider if they are currently taking or considering taking a PPI, includingomeprazole, including?

Output: starting or continuing treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients taking clopidogrel consult their healthcare provider if they are currently taking or considering taking a PPI, includingomeprazole, including?. ### Response: starting or continuing treatment.


Instruction: The ACCF has released a statement on the use of what?

Output: PPI agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ACCF has released a statement on the use of what?. ### Response: PPI agents.


Instruction: What does the expert consen-sus statement not prohibit the use of?

Output: PPI agents inappropriate clinical settings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the expert consen-sus statement not prohibit the use of?. ### Response: PPI agents inappropriate clinical settings.


Instruction: What is the potential risks andbenefits from using PPI agents in combination with clopidogrel?

Output: preventing blood clots that could lead to a heart attackor stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the potential risks andbenefits from using PPI agents in combination with clopidogrel?. ### Response: preventing blood clots that could lead to a heart attackor stroke.


Instruction: What has been well established during PCI procedures and in patients withUA/NSTEMI?

Output: Theefficacy of glycoprotein (GP) IIb/IIIa inhibitor therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been well established during PCI procedures and in patients withUA/NSTEMI?. ### Response: Theefficacy of glycoprotein (GP) IIb/IIIa inhibitor therapy.


Instruction: What are high-risk patients such as those with elevated troponin biomarkers, diabetes, and those undergoing revascularization?

Output: asthose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are high-risk patients such as those with elevated troponin biomarkers, diabetes, and those undergoing revascularization?. ### Response: asthose.


Instruction: The preponderance of evidence supporting the use of GP IIb/IIIa inhibitortherapy predated the trials that established the benefits of what?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The preponderance of evidence supporting the use of GP IIb/IIIa inhibitortherapy predated the trials that established the benefits of what?. ### Response: clopidogrel.


Instruction: What were the trials that established the benefits of clopidogrel, early invasive therapy, and contemporary medicaltreatments in patients with UA/NSTEMI?

Output: randomized clinical trial data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the trials that established the benefits of clopidogrel, early invasive therapy, and contemporary medicaltreatments in patients with UA/NSTEMI?. ### Response: randomized clinical trial data.


Instruction: What did these studies sup-port the upstream use of as a secondagent in combination with aspirin for?

Output: dual antiplatelet therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did these studies sup-port the upstream use of as a secondagent in combination with aspirin for?. ### Response: dual antiplatelet therapy.


Instruction: What are some of the high-risk subsets of UA/NSTEMI?

Output: those with an initial elevation in cardiac troponins, those withdiabetes, and in those undergoing revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the high-risk subsets of UA/NSTEMI?. ### Response: those with an initial elevation in cardiac troponins, those withdiabetes, and in those undergoing revascularization.


Instruction: What did these studies not test in a randomized fashion theselection of an oral thienopyridine versus an intravenous (IV)GP IIb/IIIa inhibitor?

Output: second antiplatelet agent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did these studies not test in a randomized fashion theselection of an oral thienopyridine versus an intravenous (IV)GP IIb/IIIa inhibitor?. ### Response: second antiplatelet agent.


Instruction: What is the second antiplatelet agent inUA/NSTEMI?

Output: GP IIb/IIIa inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the second antiplatelet agent inUA/NSTEMI?. ### Response: GP IIb/IIIa inhibitor.


Instruction: What has been needed to determine the effectiveness of the IIb/IIIa inhibitor?

Output: Contemporary clinical trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been needed to determine the effectiveness of the IIb/IIIa inhibitor?. ### Response: Contemporary clinical trials.


Instruction: Powers et al 2019 Guidelines for Management of AIS e3511.4. Hospital Stroke Capabilities1.4. What is the COR LOE New, Revised, or Unchanged?

Output: Hospital Stroke Capabilities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Powers et al 2019 Guidelines for Management of AIS e3511.4. Hospital Stroke Capabilities1.4. What is the COR LOE New, Revised, or Unchanged?. ### Response: Hospital Stroke Capabilities.


Instruction: Who certifies stroke centers?

Output: TJC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who certifies stroke centers?. ### Response: TJC.


Instruction: What is another name for the Joint Commission?

Output: TJC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for the Joint Commission?. ### Response: TJC.


Instruction: What is a cobranded stroke certification?

Output: revenue-generating

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cobranded stroke certification?. ### Response: revenue-generating.


Instruction: How was the 2013 AIS Guidelines rewritten?

Output: I B-NRRecommendation reworded for clarity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the 2013 AIS Guidelines rewritten?. ### Response: I B-NRRecommendation reworded for clarity.


Instruction: What year was the LOE amended to conform with ACC/AHA 2015 Recommendation Classification System?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the LOE amended to conform with ACC/AHA 2015 Recommendation Classification System?. ### Response: 2013.


Instruction: What does LOE support the development of to improve patient care and outcomes?

Output: stroke centers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does LOE support the development of to improve patient care and outcomes?. ### Response: stroke centers.


Instruction: How many AIS admissions were there between 2010 and 2012?

Output: 477 297

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many AIS admissions were there between 2010 and 2012?. ### Response: 477 297.


Instruction: How many stroke centers participated in the AHA GWTG-Stroke study?

Output: 977

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many stroke centers participated in the AHA GWTG-Stroke study?. ### Response: 977.


Instruction: What type of care was similar among the 4 groups of hospitals?

Output: Composite

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of care was similar among the 4 groups of hospitals?. ### Response: Composite.


Instruction: What were the rates of alteplase use in TJC- and Det Norske Veritas (9.0% and 9.8%)?

Output: higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the rates of alteplase use in TJC- and Det Norske Veritas (9.0% and 9.8%)?. ### Response: higher.


Instruction: What percentage of DTN times were longer in Healthcare Facilities Accreditation Program hospitals?

Output: 7.1% and 5.9%;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of DTN times were longer in Healthcare Facilities Accreditation Program hospitals?. ### Response: 7.1% and 5.9%;.


Instruction: State primary stroke centers had higher in-hospital risk-adjusted mortality than what type of primary stroke center?

Output: TJC-certified

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: State primary stroke centers had higher in-hospital risk-adjusted mortality than what type of primary stroke center?. ### Response: TJC-certified.


Instruction: What is the OR of a TJC-certified primary stroke center compared to?

Output: 73.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the OR of a TJC-certified primary stroke center compared to?. ### Response: 73.8%.


Instruction: What is a recommended protocol for the emergency evaluation of patients with suspected stroke?

Output: organized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a recommended protocol for the emergency evaluation of patients with suspected stroke?. ### Response: organized.


Instruction: What is recommended for patients with suspected stroke?

Output: An organized protocol for the emergency evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with suspected stroke?. ### Response: An organized protocol for the emergency evaluation.


Instruction: What is unchanged from 2013 AIS Guidelines?

Output: B-NRRecommendation and COR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unchanged from 2013 AIS Guidelines?. ### Response: B-NRRecommendation and COR.


Instruction: How is LOE amended to conform with ACC/AHA 2015 Recommendation Classification System?

Output: COR unchanged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is LOE amended to conform with ACC/AHA 2015 Recommendation Classification System?. ### Response: COR unchanged.


Instruction: What should patients with stroke have?

Output: a careful clinical assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients with stroke have?. ### Response: a careful clinical assessment.


Instruction: What should be included in a careful clinical assessment?

Output: neurological examination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be included in a careful clinical assessment?. ### Response: neurological examination.


Instruction: How was the 2013 AIS Guidelines changed to match COR I stratifications?

Output: I B-NRRecommendation wording modified

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was the 2013 AIS Guidelines changed to match COR I stratifications?. ### Response: I B-NRRecommendation wording modified.


Instruction: What is a recommendation to increase IV fibrinolytic treatment?

Output: Multicomponent quality improvement initiatives

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a recommendation to increase IV fibrinolytic treatment?. ### Response: Multicomponent quality improvement initiatives.


Instruction: What are improvement initiatives recommended to increase?

Output: IV fibrinolytic treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are improvement initiatives recommended to increase?. ### Response: IV fibrinolytic treatment.


Instruction: What are dental procedures that involve manipulation of gingival tissue?

Output: manipulation of the periapical region of teeth, or perforation of the oral mucosa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are dental procedures that involve manipulation of gingival tissue?. ### Response: manipulation of the periapical region of teeth, or perforation of the oral mucosa.


Instruction: What is a dental procedure that involves manipulation of the periapical region of teeth?

Output: manipulation of gingival tissue

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a dental procedure that involves manipulation of the periapical region of teeth?. ### Response: manipulation of gingival tissue.


Instruction: What is a prosthetic material used for cardiac valve repair?

Output: annuloplasty rings, chords, or clips

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prosthetic material used for cardiac valve repair?. ### Response: annuloplasty rings, chords, or clips.


Instruction: What are annuloplasty rings, chords, or clips used for?

Output: cardiac valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are annuloplasty rings, chords, or clips used for?. ### Response: cardiac valve repair.


Instruction: What is not recommended in patients with VHD who are at high risk of IE?

Output: antibiotic prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended in patients with VHD who are at high risk of IE?. ### Response: antibiotic prophylaxis.


Instruction: What is an example of a nondental procedure?

Output: TEE, esophagogastroduodenoscopy, colonoscopy, or cystoscopy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a nondental procedure?. ### Response: TEE, esophagogastroduodenoscopy, colonoscopy, or cystoscopy.


Instruction: What is not recommended for nondental procedures in the absence of active infection?

Output: antibiotic prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended for nondental procedures in the absence of active infection?. ### Response: antibiotic prophylaxis.


Instruction: What is recommended for secondary prevention of rheumatic fever?

Output: Antibiotics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for secondary prevention of rheumatic fever?. ### Response: Antibiotics.


Instruction: What antibiotic is used for patients allergic to penicillin and sulfadiazine?

Output: Macrolide or azalide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What antibiotic is used for patients allergic to penicillin and sulfadiazine?. ### Response: Macrolide or azalide.


Instruction: What is the duration of rheumatic fever prophylaxis in patients with documented valvular heart disease?

Output: ≥10 y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the duration of rheumatic fever prophylaxis in patients with documented valvular heart disease?. ### Response: ≥10 y.


Instruction: What is recommended if the patient is at high risk of group A streptococcus exposure?

Output: Lifelong prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended if the patient is at high risk of group A streptococcus exposure?. ### Response: Lifelong prophylaxis.


Instruction: What is required even after valve replacement?

Output: Secondary rheumatic heart disease prophylaxis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required even after valve replacement?. ### Response: Secondary rheumatic heart disease prophylaxis.


Instruction: What should not be used in people taking other medications that inhibit cytochrome P450 3A?

Output: Macrolide antibiotics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not be used in people taking other medications that inhibit cytochrome P450 3A?. ### Response: Macrolide antibiotics.


Instruction: What is an example of azole antifungal agents?

Output: HIV protease inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of azole antifungal agents?. ### Response: HIV protease inhibitors.


Instruction: How long should secondary prophylaxis for rheumatic fever last?

Output: ≥10 y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should secondary prophylaxis for rheumatic fever last?. ### Response: ≥10 y.


Instruction: What is the duration of the Rheumatic Fevertype after last attack?

Output: 21 y of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the duration of the Rheumatic Fevertype after last attack?. ### Response: 21 y of age.


Instruction: How long does the patient have to live with carditis and residual heart disease?

Output: 40 y of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does the patient have to live with carditis and residual heart disease?. ### Response: 40 y of age.


Instruction: What is another term for persistent VHD?

Output: residual heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for persistent VHD?. ### Response: residual heart disease.


Instruction: When is the patient's age whichever is longer?

Output: 40 y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the patient's age whichever is longer?. ### Response: 40 y.


Instruction: How long is rheumatic fever without carditis 5 y or until patient is 21 y of age?

Output: 10 y

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is rheumatic fever without carditis 5 y or until patient is 21 y of age?. ### Response: 10 y.


Instruction: Lifelong prophylaxis may be recommended if the patient is at high risk of group A streptococcus exposure?

Output: carditis and residual heart disease (persistent VHD†)10 y or until patient is 40 y of age (whichever is longer)Rheumatic fever with carditis but no residual heart disease (no valvular disease†)10 y or until patient is 21 y of age (whichever is longer)Rheumatic fever without carditis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Lifelong prophylaxis may be recommended if the patient is at high risk of group A streptococcus exposure?. ### Response: carditis and residual heart disease (persistent VHD†)10 y or until patient is 40 y of age (whichever is longer)Rheumatic fever with carditis but no residual heart disease (no valvular disease†)10 y or until patient is 21 y of age (whichever is longer)Rheumatic fever without carditis.


Instruction: What indicates valvular heart disease?

Output: VHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates valvular heart disease?. ### Response: VHD.


Instruction: What is recommended if meaningful survival greater than 1 year is expected?

Output: S8.4-9–S8.4-13I B-NR3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended if meaningful survival greater than 1 year is expected?. ### Response: S8.4-9–S8.4-13I B-NR3.


Instruction: What is useful for patients with recurrent episodes of idiopathic VF initiated by PVCs with a consistent QRS morphology?

Output: catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful for patients with recurrent episodes of idiopathic VF initiated by PVCs with a consistent QRS morphology?. ### Response: catheter ablation.


Instruction: When combined with clinical evaluation, genetic testing can provide a diagnosis in up to 13% to what percentage of cases?

Output: 60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When combined with clinical evaluation, genetic testing can provide a diagnosis in up to 13% to what percentage of cases?. ### Response: 60%.


Instruction: How many younger survivors of SCA are diagnosed?

Output: 13% to 60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many younger survivors of SCA are diagnosed?. ### Response: 13% to 60%.


Instruction: What are the most common genotypes associated with?

Output: long QT syndrome, catecholaminergic polymorphic ventricular tachy-cardia, and Brugada syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the most common genotypes associated with?. ### Response: long QT syndrome, catecholaminergic polymorphic ventricular tachy-cardia, and Brugada syndrome.


Instruction: Drowning/near drowning events are particularly associated with LQT1 and what?

Output: catecholaminergic polymorphic ventricular tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Drowning/near drowning events are particularly associated with LQT1 and what?. ### Response: catecholaminergic polymorphic ventricular tachycardia.


Instruction: How many patients with unexplained near-drowning episodes have genetic mutations in long QT syndrome and catecholaminergic polymorphic ventricular tachycardia?

Output: 23%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with unexplained near-drowning episodes have genetic mutations in long QT syndrome and catecholaminergic polymorphic ventricular tachycardia?. ### Response: 23%.


Instruction: What may be related to exertion-related cardiac arrest, particularly in children?

Output: long QT syndrome, catecholaminer -gic polymorphic ventricular tachycardia, or to calmodulin/triadin-mediated long QT syndrome/catecholaminergic polymorphic ventricular tachy-cardia mutations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be related to exertion-related cardiac arrest, particularly in children?. ### Response: long QT syndrome, catecholaminer -gic polymorphic ventricular tachycardia, or to calmodulin/triadin-mediated long QT syndrome/catecholaminergic polymorphic ventricular tachy-cardia mutations.


Instruction: What may be related to long QT syndrome?

Output: children

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be related to long QT syndrome?. ### Response: children.


Instruction: What may require additional specialized genetic testing?

Output: calmodulin/triadin-mediated long QT syndrome/catecholaminergic polymorphic ventricular tachy-cardia mutations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may require additional specialized genetic testing?. ### Response: calmodulin/triadin-mediated long QT syndrome/catecholaminergic polymorphic ventricular tachy-cardia mutations.


Instruction: Single-driver auto crashes should prompt the consideration of what?

Output: arrhythmic causes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Single-driver auto crashes should prompt the consideration of what?. ### Response: arrhythmic causes.


Instruction: What is the yield of genetic testing higher if a family history of SCD at a young age is present?

Output: up to 13% to 60%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the yield of genetic testing higher if a family history of SCD at a young age is present?. ### Response: up to 13% to 60%.


Instruction: Referral to specialized genetic testing centers is important if local exper -tise is unavailable?

Output: history of SCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Referral to specialized genetic testing centers is important if local exper -tise is unavailable?. ### Response: history of SCD.


Instruction: What is a structural heart disease or known genetic arrhythmia syndrome?

Output: catecholaminergic polymorphic ventricu-lar tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a structural heart disease or known genetic arrhythmia syndrome?. ### Response: catecholaminergic polymorphic ventricu-lar tachycardia.


Instruction: What is the result of short coupled PVCs arising from the Purkinje system in either the right or left ventricles?

Output: VF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the result of short coupled PVCs arising from the Purkinje system in either the right or left ventricles?. ### Response: VF.


Instruction: What is the recurrence risk after resuscitation of idiopathic VF?

Output: very high

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the recurrence risk after resuscitation of idiopathic VF?. ### Response: very high.


Instruction: How many consecutive patients underwent ablation of primary idio-pathic VF initiated by short coupled PVC?

Output: 38

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many consecutive patients underwent ablation of primary idio-pathic VF initiated by short coupled PVC?. ### Response: 38.


Instruction: What percentage had experienced 2 VF episodes in the 6 different centers?

Output: 87%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage had experienced 2 VF episodes in the 6 different centers?. ### Response: 87%.


Instruction: What percentage of couples had experienced 2 VF episodes in the preceding year?

Output: 87%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of couples had experienced 2 VF episodes in the preceding year?. ### Response: 87%.


Instruction: Why is idiopathic VF associated with Recommendations for Idopathic Polymorphic VT/VF (Continued)?

Output: if meaningful survival greater than 1 year is expected

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is idiopathic VF associated with Recommendations for Idopathic Polymorphic VT/VF (Continued)?. ### Response: if meaningful survival greater than 1 year is expected.


Instruction: On what date were the recommendations downloaded from http://ahajournals.org?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date were the recommendations downloaded from http://ahajournals.org?. ### Response: April 23, 2023.


Instruction: What does systematic review with meta-analysis of experimental and observational studies do?

Output: adult cardiometabolic health and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does systematic review with meta-analysis of experimental and observational studies do?. ### Response: adult cardiometabolic health and mortality.


Instruction: What is the PMID: 29695511?

Output: adult cardiometabolic health and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID: 29695511?. ### Response: adult cardiometabolic health and mortality.


Instruction: How long is accumulated physical activity in >/= 10 minute bouts?

Output: <10 -minute bouts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is accumulated physical activity in >/= 10 minute bouts?. ### Response: <10 -minute bouts.


Instruction: What is the difference between a 10 minute bout and a 10 minute bout?

Output: <10 -minute bouts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between a 10 minute bout and a 10 minute bout?. ### Response: <10 -minute bouts.


Instruction: When did the Am J Health Promot. 27(3):143 -151 appear?

Output: Jan-Feb 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Am J Health Promot. 27(3):143 -151 appear?. ### Response: Jan-Feb 2013.


Instruction: What was the PMID of the authors of the meta-analysis?

Output: 26553963

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID of the authors of the meta-analysis?. ### Response: 26553963.


Instruction: What is type II diabetes mellitus?

Output: obese

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is type II diabetes mellitus?. ### Response: obese.


Instruction: When did Prim Care Diabetes issue 10(3):186 -201?

Output: Jun 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Prim Care Diabetes issue 10(3):186 -201?. ### Response: Jun 2016.


Instruction: What is the PMID for Prim Care diabetes?

Output: 26553963

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for Prim Care diabetes?. ### Response: 26553963.


Instruction: What is the name of the meta -analysis of randomized controlled trials of people with type 2 diabetes mellitus?

Output: A meta -analysis of randomized controlled trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta -analysis of randomized controlled trials of people with type 2 diabetes mellitus?. ### Response: A meta -analysis of randomized controlled trials.


Instruction: What was the PMID for this meta-analysis?

Output: 29695511

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID for this meta-analysis?. ### Response: 29695511.


Instruction: How many implantations of the Carpentier-Edwards pericardial bio-prosthesis were followed up?

Output: 450

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many implantations of the Carpentier-Edwards pericardial bio-prosthesis were followed up?. ### Response: 450.


Instruction: What is the name of the procedure that improved survival after the Ross pro-cedure compared to mechanical aortic valve replacement?

Output: Ross procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure that improved survival after the Ross pro-cedure compared to mechanical aortic valve replacement?. ### Response: Ross procedure.


Instruction: What is the name of the randomised controlled trial of autograft and homograft aortic root replacement?

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised controlled trial of autograft and homograft aortic root replacement?. ### Response: Lancet.


Instruction: What are the outcomes of the Ross procedure?

Output: Improved survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the outcomes of the Ross procedure?. ### Response: Improved survival.


Instruction: How long did the Ross procedure last in adults?

Output: 25-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the Ross procedure last in adults?. ### Response: 25-year.


Instruction: What was the length of the study?

Output: 25-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the length of the study?. ### Response: 25-year.


Instruction: How old were the patients who had Ross procedures?

Output: 60 or younger

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old were the patients who had Ross procedures?. ### Response: 60 or younger.


Instruction: What year did Ann Thorac Surg. 2015:100:853-9?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Ann Thorac Surg. 2015:100:853-9?. ### Response: 2015.


Instruction: What is the STS/ACC reg-istry?

Output: Transcatheter aortic valve re-placement of failed surgically implanted bioprostheses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the STS/ACC reg-istry?. ### Response: Transcatheter aortic valve re-placement of failed surgically implanted bioprostheses.


Instruction: How old is the valve in patients?

Output: 60 or younger

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is the valve in patients?. ### Response: 60 or younger.


Instruction: How long did it take to implant a transcatheter aortic and mitral valve in a valve?

Output: 8-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take to implant a transcatheter aortic and mitral valve in a valve?. ### Response: 8-year.


Instruction: How long was it a single center experience?

Output: 8-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was it a single center experience?. ### Response: 8-year.


Instruction: What did Dvir D, Webb JG, Bleiziffer S, et al. perform in failed bioprosthetic surgical valves?

Output: Transcatheter aortic valve implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Dvir D, Webb JG, Bleiziffer S, et al. perform in failed bioprosthetic surgical valves?. ### Response: Transcatheter aortic valve implantation.


Instruction: What is the name of the registry that provides results for transcatheter aortic valve replacement for degenerative bioprosthetic surgical valves?

Output: global valve-in-valve registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry that provides results for transcatheter aortic valve replacement for degenerative bioprosthetic surgical valves?. ### Response: global valve-in-valve registry.


Instruction: What is TAVR in low-risk patients?

Output: FDA approval, the new NCD, and shared decision-making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is TAVR in low-risk patients?. ### Response: FDA approval, the new NCD, and shared decision-making.


Instruction: What is shared decision-making in cardiovascular care?

Output: Implementation of shared deci-sion making in cardiovascular care: past, present, and future

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is shared decision-making in cardiovascular care?. ### Response: Implementation of shared deci-sion making in cardiovascular care: past, present, and future.


Instruction: When did Hess EP, Coylewright M, Frosch DL, et al. implement?

Output: shared deci-sion making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Hess EP, Coylewright M, Frosch DL, et al. implement?. ### Response: shared deci-sion making.


Instruction: What year did Circ Cardio-vasc Qual Outcomes 7:797–803?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circ Cardio-vasc Qual Outcomes 7:797–803?. ### Response: 2014.


Instruction: What is the difference between mechanical prostheses and peri-cardial tissue valves?

Output: Ten-year comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between mechanical prostheses and peri-cardial tissue valves?. ### Response: Ten-year comparison.


Instruction: When was the J Thorac Cardiovasc Surg 144:1075–83 published?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg 144:1075–83 published?. ### Response: 2012.


Instruction: How long after valve replacement did the Veterans Affairs randomized trial last?

Output: 15 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after valve replacement did the Veterans Affairs randomized trial last?. ### Response: 15 years.


Instruction: What is the name of the study that evaluated the outcome of valve replacement?

Output: Veterans Affairs randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the outcome of valve replacement?. ### Response: Veterans Affairs randomized trial.


Instruction: How long after aortic valve replacement does performance of bioprostheses and mechanical prostheses assess?

Output: 15 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after aortic valve replacement does performance of bioprostheses and mechanical prostheses assess?. ### Response: 15 years.


Instruction: What is the name of the study that evaluated the performance of mechanical prosthetics and biopro-sthetics to 15 years?

Output: Veterans Affairs randomized trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the performance of mechanical prosthetics and biopro-sthetics to 15 years?. ### Response: Veterans Affairs randomized trial.


Instruction: When was the J Thorac Cardiovasc Surg. 131:1267–73?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg. 131:1267–73?. ### Response: 2006.


Instruction: What is the result of marked in-creases in volume and significant decreases in mechanical valve use?

Output: Aortic valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the result of marked in-creases in volume and significant decreases in mechanical valve use?. ### Response: Aortic valve surgery.


Instruction: Patients with preserved systolic function and LV hypertrophy are particularly susceptible to what type of episode?

Output: reduced ventricular distensibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with preserved systolic function and LV hypertrophy are particularly susceptible to what type of episode?. ### Response: reduced ventricular distensibility.


Instruction: What can small changes in ventricular volume status lead to large changes in filling pressures?

Output: reduced ventricular distensibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can small changes in ventricular volume status lead to large changes in filling pressures?. ### Response: reduced ventricular distensibility.


Instruction: What may explain why patients often improve quickly with diuresis and lowering of BP?

Output: abnormal diastolic pressure–volume relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may explain why patients often improve quickly with diuresis and lowering of BP?. ### Response: abnormal diastolic pressure–volume relationship.


Instruction: What principles apply when this occurs in the setting of ischemic cardiomyopathy as in ACS?

Output: the same principles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What principles apply when this occurs in the setting of ischemic cardiomyopathy as in ACS?. ### Response: the same principles.


Instruction: What is important in the management of hypertension in patients with ACS?

Output: Sodium restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important in the management of hypertension in patients with ACS?. ### Response: Sodium restriction.


Instruction: What are the therapeutic goals in patients presenting with HF?

Output: to reverse hemodynamic abnormalities, to relieve symptoms, and to initiate treatments that will decrease disease progres-sion and improve survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the therapeutic goals in patients presenting with HF?. ### Response: to reverse hemodynamic abnormalities, to relieve symptoms, and to initiate treatments that will decrease disease progres-sion and improve survival.


Instruction: What is important in the management of hypertension and LV dysfunction?

Output: Sodium restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important in the management of hypertension and LV dysfunction?. ### Response: Sodium restriction.


Instruction: Exercise training has been shown to reduce recurrent cardiac events in patients with what cause?

Output: LV dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise training has been shown to reduce recurrent cardiac events in patients with what cause?. ### Response: LV dysfunction.


Instruction: What was associated with exercise training in the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training study?

Output: modest reductions in both all-cause mortal-ity or hospitalization and cardiovascular mortality or HF hos-pitalization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with exercise training in the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training study?. ### Response: modest reductions in both all-cause mortal-ity or hospitalization and cardiovascular mortality or HF hos-pitalization.


Instruction: What did the Outcomes of Exercise Training (HF-ACTION) study show?

Output: modest reductions in both all-cause mortal-ity or hospitalization and cardiovascular mortality or HF hos-pitalization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Outcomes of Exercise Training (HF-ACTION) study show?. ### Response: modest reductions in both all-cause mortal-ity or hospitalization and cardiovascular mortality or HF hos-pitalization.


Instruction: Exercise training was associated with modest reductions in all-cause mortal-ity or hospitalization and cardiovascular mortality after adjustment for what?

Output: highly prognostic baseline characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise training was associated with modest reductions in all-cause mortal-ity or hospitalization and cardiovascular mortality after adjustment for what?. ### Response: highly prognostic baseline characteristics.


Instruction: What did exercise training confer significant improvements in?

Output: self-reported health status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did exercise training confer significant improvements in?. ### Response: self-reported health status.


Instruction: What is an example of a nonpharmacological therapy for HF patients?

Output: Sodium restriction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of a nonpharmacological therapy for HF patients?. ### Response: Sodium restriction.


Instruction: What is a risk factor of HF?

Output: reduced ventricular distensibility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor of HF?. ### Response: reduced ventricular distensibility.


Instruction: What should remain the primary goal when an antihypertensive regimen is devised?

Output: optimal con-trol of BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should remain the primary goal when an antihypertensive regimen is devised?. ### Response: optimal con-trol of BP.


Instruction: What should be determined by the concomitant medical problems?

Output: the choice of drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be determined by the concomitant medical problems?. ### Response: the choice of drugs.


Instruction: What is a concomitant medical problem that determines an antihypertensive regimen?

Output: CAD, diabetes mellitus, or renal disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a concomitant medical problem that determines an antihypertensive regimen?. ### Response: CAD, diabetes mellitus, or renal disease.


Instruction: What type of therapy has been shown to prevent HF in a wide range of target populations?

Output: antihypertensive therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy has been shown to prevent HF in a wide range of target populations?. ### Response: antihypertensive therapy.


Instruction: What are effective in prevent-ing HF in hypertensive patients?

Output: Thiazide or thiazide-type diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are effective in prevent-ing HF in hypertensive patients?. ### Response: Thiazide or thiazide-type diuretics.


Instruction: What are the drugs of choice in patients with mild HF because of their more sustained natriuretic and diuretic action?

Output: Thiazide or thiazide-type diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the drugs of choice in patients with mild HF because of their more sustained natriuretic and diuretic action?. ### Response: Thiazide or thiazide-type diuretics.


Instruction: What may be more important than correction of volume overload?

Output: BP control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be more important than correction of volume overload?. ### Response: BP control.


Instruction: In severe HF, what are diuretics used to reverse?

Output: vol-ume overload and associated symptoms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In severe HF, what are diuretics used to reverse?. ### Response: vol-ume overload and associated symptoms.


Instruction: What is a loop diuretic?

Output: antihypertensive therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a loop diuretic?. ### Response: antihypertensive therapy.


Instruction: What is the name of the 2018 Cholesterol Clinical Practice Guidelines?

Output: Grundy et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2018 Cholesterol Clinical Practice Guidelines?. ### Response: Grundy et al.


Instruction: What does PCE stand for?

Output: Framingham risk scoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PCE stand for?. ### Response: Framingham risk scoring.


Instruction: What did the 2013 ACC/AHA guidelinesS8.2-1 introduce to facilitate clinical decisions about appropriate therapy?

Output: clinician–patient risk discussion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the 2013 ACC/AHA guidelinesS8.2-1 introduce to facilitate clinical decisions about appropriate therapy?. ### Response: clinician–patient risk discussion.


Instruction: What has been amplified and made an integral part of the clinical decision?

Output: clinician–patient risk discussion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been amplified and made an integral part of the clinical decision?. ### Response: clinician–patient risk discussion.


Instruction: What is proposed as a third step in making a treatment decision?

Output: the mea-surement of CAC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is proposed as a third step in making a treatment decision?. ### Response: the mea-surement of CAC.


Instruction: What could each of these steps be improved for?

Output: future guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could each of these steps be improved for?. ### Response: future guidelines.


Instruction: Why may the population baseline risk be continually declining?

Output: ongoing epidemiological study is needed to assess and update population risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why may the population baseline risk be continually declining?. ### Response: ongoing epidemiological study is needed to assess and update population risk.


Instruction: What type of study is needed to assess and update population risk?

Output: ongoing epidemiological

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of study is needed to assess and update population risk?. ### Response: ongoing epidemiological.


Instruction: What is expanding its scope in the U.K. Population?

Output: popula-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is expanding its scope in the U.K. Population?. ### Response: popula-tion.


Instruction: What is the scope of the ASCVD risk al-gorithm?

Output: 20 to 59 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the scope of the ASCVD risk al-gorithm?. ### Response: 20 to 59 years of age.


Instruction: What does the present guidelines include for those 20 to 59 years of age?

Output: a lifetime ASCVD risk al-gorithm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the present guidelines include for those 20 to 59 years of age?. ### Response: a lifetime ASCVD risk al-gorithm.


Instruction: The present guidelines are based on what?

Output: the available data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The present guidelines are based on what?. ### Response: the available data.


Instruction: How long is ASCVD?

Output: 10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is ASCVD?. ### Response: 10 years.


Instruction: A more robust lifetime risk algorithm would facilitate the clini-cian-patient risk discussion for what?

Output: treatment decisions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A more robust lifetime risk algorithm would facilitate the clini-cian-patient risk discussion for what?. ### Response: treatment decisions.


Instruction: What must be done to make an informed decision?

Output: taking multiple factors into consideration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must be done to make an informed decision?. ### Response: taking multiple factors into consideration.


Instruction: What is meant to be a lifetime therapy?

Output: cholesterol-lowering therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is meant to be a lifetime therapy?. ### Response: cholesterol-lowering therapy.


Instruction: Monitoring and adjustment of treatment will likely prove in-adequate unless an ongoing interaction between the patient and clinician occurs?

Output: clinician–patient risk discussion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Monitoring and adjustment of treatment will likely prove in-adequate unless an ongoing interaction between the patient and clinician occurs?. ### Response: clinician–patient risk discussion.


Instruction: What does monitoring the effectiveness of therapy and adherence to therapy involve?

Output: ongoing interaction between the patient and clinician

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does monitoring the effectiveness of therapy and adherence to therapy involve?. ### Response: ongoing interaction between the patient and clinician.


Instruction: What should in-clude more than the initial treatment decision?

Output: clinician–patient risk discussion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should in-clude more than the initial treatment decision?. ### Response: clinician–patient risk discussion.