Instruction: How old are the females and males in a gglomerate of egFR?

Output: 40– 50 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are the females and males in a gglomerate of egFR?. ### Response: 40– 50 years.


Instruction: What is the age range of the eGFR G1-G4?

Output: 40– 50 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the age range of the eGFR G1-G4?. ### Response: 40– 50 years.


Instruction: What are the ages of egfrg1-g4)?

Output: 40– 50 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the ages of egfrg1-g4)?. ### Response: 40– 50 years.


Instruction: How many years is the average age range for egefrrg3a-g4??

Output: 19.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years is the average age range for egefrrg3a-g4??. ### Response: 19.3.


Instruction: What is the eGFR G3a-G4?

Output: 19.9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the eGFR G3a-G4?. ### Response: 19.9.


Instruction: What are the abbreviations for CKD?

Output: chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the abbreviations for CKD?. ### Response: chronic kidney disease.


Instruction: How many participants were in the Alberta Kidney Disease cohort?

Output: 1,268,029

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many participants were in the Alberta Kidney Disease cohort?. ### Response: 1,268,029.


Instruction: What were people with diabetes, MI, and other cardiovascular dise ase included in?

Output: Alberta Kidney Disease cohort

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were people with diabetes, MI, and other cardiovascular dise ase included in?. ### Response: Alberta Kidney Disease cohort.


Instruction: Data do not apply to people with what?

Output: kidney transplants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data do not apply to people with what?. ### Response: kidney transplants.


Instruction: What is the 2017 VA/SCD Guideline?

Output: September 25, 2018 Circulation. 2018;138:e272–e391

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 VA/SCD Guideline?. ### Response: September 25, 2018 Circulation. 2018;138:e272–e391.


Instruction: What are the costs and value considerations?

Output: Quality of Life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the costs and value considerations?. ### Response: Quality of Life.


Instruction: Evidence Gaps and Future Research Needs..............

Output: e35318

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence Gaps and Future Research Needs............... ### Response: e35318.


Instruction: What is the acronym for the American College of Cardiology?

Output: ACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology?. ### Response: ACC.


Instruction: What does AHA stand for?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AHA stand for?. ### Response: American Heart Association.


Instruction: Since 1980, what have the ACC and AHA done?

Output: translated scientific evidence into clinical practice guidelines with recommendations to improve cardiovascular health

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Since 1980, what have the ACC and AHA done?. ### Response: translated scientific evidence into clinical practice guidelines with recommendations to improve cardiovascular health.


Instruction: What two organizations have translated scientific evidence into clinical practice guidelines with recommendations to improve cardiovascular health?

Output: American College of Cardiology (ACC) and American Heart Association (AHA)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What two organizations have translated scientific evidence into clinical practice guidelines with recommendations to improve cardiovascular health?. ### Response: American College of Cardiology (ACC) and American Heart Association (AHA).


Instruction: What do the guidelines based on systematic meth-ods evaluate and classify evidence provide?

Output: a corner -stone for quality cardiovascular care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the guidelines based on systematic meth-ods evaluate and classify evidence provide?. ### Response: a corner -stone for quality cardiovascular care.


Instruction: Who sponsor the development and publication of guidelines without commercial support?

Output: The ACC and AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who sponsor the development and publication of guidelines without commercial support?. ### Response: The ACC and AHA.


Instruction: Who volunteer their time to the writing and review efforts of guidelines?

Output: members of each or -ganization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who volunteer their time to the writing and review efforts of guidelines?. ### Response: members of each or -ganization.


Instruction: What is official policy of the ACC and AHA?

Output: Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is official policy of the ACC and AHA?. ### Response: Guidelines.


Instruction: What do UsePractice guidelines provide recommendations for?

Output: patients with or at risk of developing cardiovas-cular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do UsePractice guidelines provide recommendations for?. ### Response: patients with or at risk of developing cardiovas-cular disease.


Instruction: Where is the focus of the Usepractice guidelines?

Output: medical practice in the United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the focus of the Usepractice guidelines?. ### Response: medical practice in the United States.


Instruction: What may the guidelines developed in collaboration with other organizations have a global impact?

Output: quality cardiovascular care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may the guidelines developed in collaboration with other organizations have a global impact?. ### Response: quality cardiovascular care.


Instruction: Guidelines are intended to define practices meeting the needs of patients in most but not all circumstances and should not replace what?

Output: clinical judgment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Guidelines are intended to define practices meeting the needs of patients in most but not all circumstances and should not replace what?. ### Response: clinical judgment.


Instruction: Guideline-recommended management is effective when it comes to improving patients' quality of care.

Output: guidelines may be used to inform regulatory or payer decisions, their intent is to improve patients’ quality of care and align with patients’ interests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Guideline-recommended management is effective when it comes to improving patients' quality of care.. ### Response: guidelines may be used to inform regulatory or payer decisions, their intent is to improve patients’ quality of care and align with patients’ interests.


Instruction: What should not replace clinical judgment?

Output: Guide-lines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should not replace clinical judgment?. ### Response: Guide-lines.


Instruction: What is effective when followed by healthcare providers and patients?

Output: ideline-recommended management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is effective when followed by healthcare providers and patients?. ### Response: ideline-recommended management.


Instruction: Adherence to recommendations can be enhanced by sharing decision-making between healthcare providers and patients.

Output: Clinical Implementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adherence to recommendations can be enhanced by sharing decision-making between healthcare providers and patients.. ### Response: Clinical Implementation.


Instruction: What is the ACC/AHA Task Force on Clinical Practice Guidelines known as?

Output: Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA Task Force on Clinical Practice Guidelines known as?. ### Response: Task Force.


Instruction: What does the Task Force update and modi-fie on the basis of published standards?

Output: guideline methodology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Task Force update and modi-fie on the basis of published standards?. ### Response: guideline methodology.


Instruction: On the basis of internal reevaluation, how are presentation and delivery of guidelines re-evaluated and modified?

Output: evolving tech-nologies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On the basis of internal reevaluation, how are presentation and delivery of guidelines re-evaluated and modified?. ### Response: evolving tech-nologies.


Instruction: To facilitate optimal dissemi-nation of information at the point of care to healthcare professionals, what is the goal of this guideline?

Output: improve patients’ quality of care and align with patients’ interests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To facilitate optimal dissemi-nation of information at the point of care to healthcare professionals, what is the goal of this guideline?. ### Response: improve patients’ quality of care and align with patients’ interests.


Instruction: What is the goal of the module knowledge chunk format?

Output: the introduction of an evolved format of presenting guideline recommenda-tions and associated text

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of the module knowledge chunk format?. ### Response: the introduction of an evolved format of presenting guideline recommenda-tions and associated text.


Instruction: What does each modular knowledge chunk include?

Output: a table

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does each modular knowledge chunk include?. ### Response: a table.


Instruction: What is NICE 2018?

Output: Chronic Heart Failure  Monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE 2018?. ### Response: Chronic Heart Failure  Monitoring.


Instruction: What is the subject of Notice of rights?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the subject of Notice of rights?. ### Response: Chronic Heart Failure.


Instruction: What group discussed people who may not be able to access STS?

Output: The committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group discussed people who may not be able to access STS?. ### Response: The committee.


Instruction: What groups did the committee discuss?

Output: people who may not be able to access STS which included those from socioeconomically disadvantaged groups

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What groups did the committee discuss?. ### Response: people who may not be able to access STS which included those from socioeconomically disadvantaged groups.


Instruction: People whose first language is not English may have difficulty accessing what?

Output: touch tone telep hone. In addition, people whose first language is not English may also have difficulty accessing this form of support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People whose first language is not English may have difficulty accessing what?. ### Response: touch tone telep hone. In addition, people whose first language is not English may also have difficulty accessing this form of support.


Instruction: What may have difficulty accessing this form of support?

Output: people whose first language is not English

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have difficulty accessing this form of support?. ### Response: people whose first language is not English.


Instruction: What should all people with chronic heart failure need monitoring?

Output: a clinical assessment of functional capacity, fluid status, cardiac rhythm (minimum of examining the pulse), cognitive status and nutritional status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should all people with chronic heart failure need monitoring?. ### Response: a clinical assessment of functional capacity, fluid status, cardiac rhythm (minimum of examining the pulse), cognitive status and nutritional status.


Instruction: What is a clinical assessment of?

Output: functional capacity, fluid status, cardiac rhythm (minimum of examining the pulse), cognitive status and nutritional status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a clinical assessment of?. ### Response: functional capacity, fluid status, cardiac rhythm (minimum of examining the pulse), cognitive status and nutritional status.


Instruction: What is an assessment of renal functiond?

Output: a review of medication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an assessment of renal functiond?. ### Response: a review of medication.


Instruction: What should be monitored if a person has significant comorbidity or if their condition has deteriorated since the previous review?

Output: serum potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be monitored if a person has significant comorbidity or if their condition has deteriorated since the previous review?. ### Response: serum potassium.


Instruction: What should the frequency of monitoring depend on?

Output: the clinical st atus and stability of the person

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the frequency of monitoring depend on?. ### Response: the clinical st atus and stability of the person.


Instruction: How often should a person be monitored for heart failure?

Output: All people with chronic heart failure need monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often should a person be monitored for heart failure?. ### Response: All people with chronic heart failure need monitoring.


Instruction: What should be short if the clinical condition or medication has changed?

Output: The monitoring interval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be short if the clinical condition or medication has changed?. ### Response: The monitoring interval.


Instruction: How often is it needed for stable people with proven heart failure to be monitored?

Output: 6 -monthly

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often is it needed for stable people with proven heart failure to be monitored?. ### Response: 6 -monthly.


Instruction: What should people with heart failure be provided with in order to monitor their condition?

Output: serum potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should people with heart failure be provided with in order to monitor their condition?. ### Response: serum potassium.


Instruction: What should be provided to people who wish to be involved in monitoring their condition by their healthcare professional?

Output: sufficient education and support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be provided to people who wish to be involved in monitoring their condition by their healthcare professional?. ### Response: sufficient education and support.


Instruction: What is NT -proBNP?

Output: N -terminal pro -B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NT -proBNP?. ### Response: N -terminal pro -B-type natriuretic peptide.


Instruction: What is N -terminal pro -B-type natriuretic peptide?

Output: BNP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is N -terminal pro -B-type natriuretic peptide?. ### Response: BNP.


Instruction: What is the eGFR for people under 75 who have heart failure?

Output: above 60 ml/min/1.73  m2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the eGFR for people under 75 who have heart failure?. ### Response: above 60 ml/min/1.73  m2.


Instruction: d What is the name of the product that is being produced?

Output: N -terminal pro -B-type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: d What is the name of the product that is being produced?. ### Response: N -terminal pro -B-type natriuretic peptide.


Instruction: What are people with comorbidities or co -prescribed medications likely to need further monitoring?

Output: serum potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are people with comorbidities or co -prescribed medications likely to need further monitoring?. ### Response: serum potassium.


Instruction: What is particularly important if a person is taking digoxin or an aldosterone antagonist?

Output: Monitoring serum potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is particularly important if a person is taking digoxin or an aldosterone antagonist?. ### Response: Monitoring serum potassium.


Instruction: What year did Al-Khatib publish the VA/SCD GuidelineCirculation. 2018;138:e272–e391. DOI: 10.1161/CIR.0000000000000549 September 25, 2018 e367Clinical STATEMENTS AND GUIDELINESmapping and irrigated ablation technology: results of the pro-spective multicenter Euro-VT-study. 2010;21:47–53. What is freedom from after catheter ablation associated with?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Al-Khatib publish the VA/SCD GuidelineCirculation. 2018;138:e272–e391. DOI: 10.1161/CIR.0000000000000549 September 25, 2018 e367Clinical STATEMENTS AND GUIDELINESmapping and irrigated ablation technology: results of the pro-spective multicenter Euro-VT-study. 2010;21:47–53. What is freedom from after catheter ablation associated with?. ### Response: 2017.


Instruction: What is associated with improved survival in patients with structural heart disease?

Output: ventricular tachycardia after catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with improved survival in patients with structural heart disease?. ### Response: ventricular tachycardia after catheter ablation.


Instruction: What is the name of the study that found catheter ablation to be associated with ventricular tachycardia?

Output: International VT Ablation Center Collaborative Group study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that found catheter ablation to be associated with ventricular tachycardia?. ### Response: International VT Ablation Center Collaborative Group study.


Instruction: When was the last year of Heart Rhythm published?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last year of Heart Rhythm published?. ### Response: 2007.


Instruction: What is the name of the pilot trial of catheter ablation for ventricular tachycardia in patients with an implantable cardioverter defibrillator?

Output: CALYPSO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the pilot trial of catheter ablation for ventricular tachycardia in patients with an implantable cardioverter defibrillator?. ### Response: CALYPSO.


Instruction: When was the J Cardiovasc Electrophysiol. 2015:26:151–7. What is VTACH?

Output: Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Cardiovasc Electrophysiol. 2015:26:151–7. What is VTACH?. ### Response: Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease.


Instruction: What is VTACH?

Output: Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is VTACH?. ### Response: Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease.


Instruction: What is the name of the multicentre ran-domised controlled trial?

Output: Euro-VT-study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicentre ran-domised controlled trial?. ### Response: Euro-VT-study.


Instruction: When was the Lancet 375:31-40?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet 375:31-40?. ### Response: 2010.


Instruction: How many patients were treated with implantable defibrillators?

Output: 1.3-11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were treated with implantable defibrillators?. ### Response: 1.3-11.


Instruction: What is the name of the study that examined the psychoso-cial impact of implantable cardioverter defibrillators?

Output: a literature review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the psychoso-cial impact of implantable cardioverter defibrillators?. ### Response: a literature review.


Instruction: What are the names of the three drugs that are used to treat cardiac arrhythmias?

Output: encainide, flecainide, or placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the three drugs that are used to treat cardiac arrhythmias?. ### Response: encainide, flecainide, or placebo.


Instruction: What is the psychoso-cial impact of implantable cardioverter defibrillators?

Output: Ventricular arrhythmia storms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the psychoso-cial impact of implantable cardioverter defibrillators?. ### Response: Ventricular arrhythmia storms.


Instruction: When did Steinberg JS, Gaur A, Sciacca R, et al. develop new-onset sustained ventricular tachycardia after cardiac surgery?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Steinberg JS, Gaur A, Sciacca R, et al. develop new-onset sustained ventricular tachycardia after cardiac surgery?. ### Response: 1999.


Instruction: What is revascularization in patients with sustained ventricular arrhythmias?

Output: Coronary artery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is revascularization in patients with sustained ventricular arrhythmias?. ### Response: Coronary artery.


Instruction: What does revasculariza-tion do in patients with sustained ventricular arrhythmias in the chronic phase of a myocardial infarction?

Output: effects on the electrophysiologic substrate and outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does revasculariza-tion do in patients with sustained ventricular arrhythmias in the chronic phase of a myocardial infarction?. ### Response: effects on the electrophysiologic substrate and outcome.


Instruction: When did J Am Coll Cardiol. 2001;37:529–33?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2001;37:529–33?. ### Response: 2001.


Instruction: What did Claro JC, Candia R, Rada G, et al. compare Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death?

Output: phar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Claro JC, Candia R, Rada G, et al. compare Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death?. ### Response: phar.


Instruction: What does Ranolazine reduce in patients with drug-refractory ICD shocks?

Output: ven-tricular tachycardia burden and ICD shocks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Ranolazine reduce in patients with drug-refractory ICD shocks?. ### Response: ven-tricular tachycardia burden and ICD shocks.


Instruction: What is the name of the Cochrane Database Syst Rev. 2015?

Output: 12:CD008093

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Cochrane Database Syst Rev. 2015?. ### Response: 12:CD008093.


Instruction: Which drug reduces ven-tricular tachycardia burden?

Output: Ranolazine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug reduces ven-tricular tachycardia burden?. ### Response: Ranolazine.


Instruction: What is a practical guide for clinicians who treat patients with amiodarone?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a practical guide for clinicians who treat patients with amiodarone?. ### Response: 2007.


Instruction: What is the name of the survival trial of antiarrhythmic therapy for patients with congestive heart failure and asymptomatic ventricular arrhythmia?

Output: The Cardiac Arrhythmia Suppression Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the survival trial of antiarrhythmic therapy for patients with congestive heart failure and asymptomatic ventricular arrhythmia?. ### Response: The Cardiac Arrhythmia Suppression Trial.


Instruction: What is asymptomatic ventricular arrhythmia?

Output: implantable defibrillators for primary prevention indications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic ventricular arrhythmia?. ### Response: implantable defibrillators for primary prevention indications.


Instruction: What is the Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure?

Output: 1995;333:77–82

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure?. ### Response: 1995;333:77–82.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: When was the 2021 Circulation. 2021:143:e72–e227?

Output: February 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2021 Circulation. 2021:143:e72–e227?. ### Response: February 2.


Instruction: What was the expected durability of a bioprosthetic mitral valve replacement in patients 60 years of age?

Output: 11.4 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the expected durability of a bioprosthetic mitral valve replacement in patients 60 years of age?. ### Response: 11.4 years.


Instruction: What was the overall survival rate for patients 70 to 79 years of age?

Output: similar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the overall survival rate for patients 70 to 79 years of age?. ### Response: similar.


Instruction: How many years were reported in 2017 by the California Office of Statewide Health Planning and Development?

Output: 11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years were reported in 2017 by the California Office of Statewide Health Planning and Development?. ### Response: 11.


Instruction: What was lower with a bioprosthetic valve?

Output: bleeding risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was lower with a bioprosthetic valve?. ### Response: bleeding risk.


Instruction: What is a pulmo-nary autograft?

Output: Ross procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pulmo-nary autograft?. ### Response: Ross procedure.


Instruction: What procedure allows the patient to avoid a prosthetic heart valve and the risks of antico-agulation?

Output: Ross procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What procedure allows the patient to avoid a prosthetic heart valve and the risks of antico-agulation?. ### Response: Ross procedure.


Instruction: What procedure provides excellent valve hemodynamics?

Output: Ross procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What procedure provides excellent valve hemodynamics?. ### Response: Ross procedure.


Instruction: What type of hemody-namics does the Ross procedure provide?

Output: excellent valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of hemody-namics does the Ross procedure provide?. ### Response: excellent valve.


Instruction: The pulmonic homograft and the pulmonary autograft are at risk of what?

Output: valve degeneration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The pulmonic homograft and the pulmonary autograft are at risk of what?. ### Response: valve degeneration.


Instruction: What is most often attributable to the failure of the Ross Procedure?

Output: regurgitation of the neoaortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is most often attributable to the failure of the Ross Procedure?. ### Response: regurgitation of the neoaortic valve.


Instruction: When does the neoaortic valve reopen after the operation?

Output: second decade

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When does the neoaortic valve reopen after the operation?. ### Response: second decade.


Instruction: How long do most pulmonic homograft valves need to be reintervention?

Output: 10 to 20 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long do most pulmonic homograft valves need to be reintervention?. ### Response: 10 to 20 years.


Instruction: What procedure is reserved for reoperation?

Output: pulmo-nary autograft

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What procedure is reserved for reoperation?. ### Response: pulmo-nary autograft.


Instruction: When is the Ross procedure reserved?

Output: younger patients with appropriate anatomy and tissue characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is the Ross procedure reserved?. ### Response: younger patients with appropriate anatomy and tissue characteristics.


Instruction: What procedure is reserved for younger patients with appropriate anatomy and tissue characteristics?

Output: Ross procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What procedure is reserved for younger patients with appropriate anatomy and tissue characteristics?. ### Response: Ross procedure.


Instruction: Who performs the Ross procedure at Comprehensive Valve Centers?

Output: surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who performs the Ross procedure at Comprehensive Valve Centers?. ### Response: surgeons.


Instruction: What are the recommendations for Antithrombotic Therapy for Prosthetic Valves?

Output: Antithrombotic Therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the recommendations for Antithrombotic Therapy for Prosthetic Valves?. ### Response: Antithrombotic Therapy.


Instruction: What is recommended in patients with a mechanical prosthetic valve?

Output: anticoagulation with a VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended in patients with a mechanical prosthetic valve?. ### Response: anticoagulation with a VKA.


Instruction: What is the name of the online data supplement that summarizes the recommendations for antithrombotic therapy for prosthetic valves?

Output: 36

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the online data supplement that summarizes the recommendations for antithrombotic therapy for prosthetic valves?. ### Response: 36.


Instruction: What is recommended for patients with a mechanical bileaflet or current-generation single-tilting disk AVR and no risk factors for thromboembolism?

Output: anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with a mechanical bileaflet or current-generation single-tilting disk AVR and no risk factors for thromboembolism?. ### Response: anticoagulation.


Instruction: What is the INR of a VKA to achieve?

Output: 2.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the INR of a VKA to achieve?. ### Response: 2.5.


Instruction: What is a risk factor for thromboembolism?

Output: AF, previous thromboembolism, LV dysfunction, hypercoagulable state

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk factor for thromboembolism?. ### Response: AF, previous thromboembolism, LV dysfunction, hypercoagulable state.


Instruction: What is an example of an older-generation prosthesis?

Output: ball-in-cage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an example of an older-generation prosthesis?. ### Response: ball-in-cage.


Instruction: Anticoagulation with a VKA is indicated to achieve an INR of what?

Output: 2.5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Anticoagulation with a VKA is indicated to achieve an INR of what?. ### Response: 2.5.


Instruction: What is indicated to achieve an INR of 3.0.9,11 2a B-R 5 for patients with a bioprosthetic TAVI?

Output: anticoagulation with a VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated to achieve an INR of 3.0.9,11 2a B-R 5 for patients with a bioprosthetic TAVI?. ### Response: anticoagulation with a VKA.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: When was the 2021 Circulation. 143:e72–e227?

Output: February 2, 2021 Circulation. 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the 2021 Circulation. 143:e72–e227?. ### Response: February 2, 2021 Circulation. 2021.


Instruction: What are the differences based on?

Output: primary cardiac lesion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences based on?. ### Response: primary cardiac lesion.


Instruction: What is the name of the quality control exercise used to assess right ventricular size and systolic function?

Output: Accuracy and interobserver concordance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the quality control exercise used to assess right ventricular size and systolic function?. ### Response: Accuracy and interobserver concordance.


Instruction: When did the J Am Soc Echocardiogr. 2012 issue 25?

Output: 2012;25:709–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Soc Echocardiogr. 2012 issue 25?. ### Response: 2012;25:709–.


Instruction: What did Rudski LG, Lai WW, Afilalo J, et al. write about?

Output: Guidelines for the echocardiographic assessment of the right heart in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Rudski LG, Lai WW, Afilalo J, et al. write about?. ### Response: Guidelines for the echocardiographic assessment of the right heart in adults.


Instruction: What is a report from the American Society of Echocardiography?

Output: Guidelines for the echocardiographic assessment of the right heart in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report from the American Society of Echocardiography?. ### Response: Guidelines for the echocardiographic assessment of the right heart in adults.


Instruction: What is the name of the group that evaluated the right heart in adults?

Output: American Society of Echocardiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that evaluated the right heart in adults?. ### Response: American Society of Echocardiography.


Instruction: When was the J Am Soc Echocardiogr. 23:685–713.8.2.2?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Soc Echocardiogr. 23:685–713.8.2.2?. ### Response: 2010.


Instruction: What is oxide and iloprost used for in patients with pulmonary hypertension and right ventricular dysfunction after high-risk cardiac surgery?

Output: com-bination therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is oxide and iloprost used for in patients with pulmonary hypertension and right ventricular dysfunction after high-risk cardiac surgery?. ### Response: com-bination therapy.


Instruction: What is the J Cardiothorac Vasc Anesth. 2013;27:459–66?

Output: effects of com-bination therapy with inhaled nitric oxide and iloprost in patients with pulmonary hypertension and right ventricular dysfunction after high-risk cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Cardiothorac Vasc Anesth. 2013;27:459–66?. ### Response: effects of com-bination therapy with inhaled nitric oxide and iloprost in patients with pulmonary hypertension and right ventricular dysfunction after high-risk cardiac surgery.


Instruction: Who wrote the ACCF/AHA 2009 expert consen-sus document?

Output: McLaughlin VV, Archer SL, Badesch DB, et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the ACCF/AHA 2009 expert consen-sus document?. ### Response: McLaughlin VV, Archer SL, Badesch DB, et al.


Instruction: Who developed the Task Force on Expert Consensus Documents?

Output: American College of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who developed the Task Force on Expert Consensus Documents?. ### Response: American College of Cardiology Foundation.


Instruction: What is the name of the group that developed the task force?

Output: American College of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that developed the task force?. ### Response: American College of Cardiology Foundation.


Instruction: Who is a member of the Pulmonary Hypertension Association?

Output: acic Society, Inc.;

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the Pulmonary Hypertension Association?. ### Response: acic Society, Inc.;.


Instruction: What year did Cardiol. 2009:53:1573-619?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Cardiol. 2009:53:1573-619?. ### Response: 2009.


Instruction: What is the impact of surgical ablation of atrial fibrillation on the progression of tricuspid regurgitation and right-sided heart remodel-ing after mitral-valve surgery?

Output: propensity-score matching analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of surgical ablation of atrial fibrillation on the progression of tricuspid regurgitation and right-sided heart remodel-ing after mitral-valve surgery?. ### Response: propensity-score matching analysis.


Instruction: What procedure halts progression of tricuspid regurgitation after mitral surgery?

Output: us rhythm by the Maze

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What procedure halts progression of tricuspid regurgitation after mitral surgery?. ### Response: us rhythm by the Maze.


Instruction: What is Staab ME, Nishimura RA, Dearani JA's specialty?

Output: Isolated tricuspid valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Staab ME, Nishimura RA, Dearani JA's specialty?. ### Response: Isolated tricuspid valve surgery.


Instruction: How many patients underwent tricuspid valve surgery in 1999?

Output: 34

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent tricuspid valve surgery in 1999?. ### Response: 34.


Instruction: What is the name of the database used for tricuspid valve surgeries?

Output: Nationwide Inpatient Sample (NIS)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the database used for tricuspid valve surgeries?. ### Response: Nationwide Inpatient Sample (NIS).


Instruction: When was the last 10 years of the National Inpatient Sample database used?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last 10 years of the National Inpatient Sample database used?. ### Response: 2012.


Instruction: How many years from the Nationwide Inpatient Sample (NIS) database?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many years from the Nationwide Inpatient Sample (NIS) database?. ### Response: 10.


Instruction: What should be the criteria for surgical repair?

Output: Secondary tricuspid regurgitation or dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be the criteria for surgical repair?. ### Response: Secondary tricuspid regurgitation or dilatation.


Instruction: What type of regurgitation with left-sided degenerative heart valve disease is to repair or not to repair?

Output: Moderate tricuspid

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of regurgitation with left-sided degenerative heart valve disease is to repair or not to repair?. ### Response: Moderate tricuspid.


Instruction: What is the name of the procedure performed in patients with dilated tricuspid annulus undergoing mitral valve surgery?

Output: Prophylactic tricuspid annulo-plasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure performed in patients with dilated tricuspid annulus undergoing mitral valve surgery?. ### Response: Prophylactic tricuspid annulo-plasty.


Instruction: What can be very brief in urgent settings?

Output: education

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be very brief in urgent settings?. ### Response: education.


Instruction: What should the patient be provided if any uncertainty exists about the superiority of PCI versusoptimal medical therapy or surgical revascularization?

Output: an opportunity to learn about the relative risksand bene ﬁts of therapies under consideration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the patient be provided if any uncertainty exists about the superiority of PCI versusoptimal medical therapy or surgical revascularization?. ### Response: an opportunity to learn about the relative risksand bene ﬁts of therapies under consideration.


Instruction: What should the patient learn about the relative risks andbenefits of therapies under consideration?

Output: ifany uncertainty exists about the superiority of PCI versusoptimal medical therapy or surgical revascularization (as isusually the case with elective PCI), then the patient shouldbe provided an opportunity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the patient learn about the relative risks andbenefits of therapies under consideration?. ### Response: ifany uncertainty exists about the superiority of PCI versusoptimal medical therapy or surgical revascularization (as isusually the case with elective PCI), then the patient shouldbe provided an opportunity.


Instruction: The writing committee struggled with whether to include what?

Output: process measures that focused on decision makingand education through patient surveys

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The writing committee struggled with whether to include what?. ### Response: process measures that focused on decision makingand education through patient surveys.


Instruction: What could be able to address general quality of decisions?

Output: Surveys

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could be able to address general quality of decisions?. ### Response: Surveys.


Instruction: What could the results of the survey be shared at?

Output: physician and hospital levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What could the results of the survey be shared at?. ### Response: physician and hospital levels.


Instruction: Who could understand and improve their decision making processes?

Output: individual cliniciansand institutions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who could understand and improve their decision making processes?. ### Response: individual cliniciansand institutions.


Instruction: What are there yet novalidated instruments addressing?

Output: Survey results could then be shared at thephysician and hospital levels, so both individual cliniciansand institutions could understand and improve theirdecision-making processes. However, there are as yet novalidated instruments addressing these domains

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are there yet novalidated instruments addressing?. ### Response: Survey results could then be shared at thephysician and hospital levels, so both individual cliniciansand institutions could understand and improve theirdecision-making processes. However, there are as yet novalidated instruments addressing these domains.


Instruction: What are the limitations of the writing committee?

Output: there are as yet novalidated instruments addressing these domains, nor haveother critical details been worked out

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the limitations of the writing committee?. ### Response: there are as yet novalidated instruments addressing these domains, nor haveother critical details been worked out.


Instruction: What do outcome measures shed light on rather than the means?

Output: destinationd theend

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do outcome measures shed light on rather than the means?. ### Response: destinationd theend.


Instruction: Outcome measures offer the advantage of providing readouts on entirepopulations rather than smaller population subsets.

Output: outcome measures shed light on the destinationd theend, rather than the means. Outcome measures offer thepotential advantage of providing readouts on entirepopulations, rather than smaller population subsets, andthey focus on the “end results ”of care that are mostimportant to clinicians and pa tients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Outcome measures offer the advantage of providing readouts on entirepopulations rather than smaller population subsets.. ### Response: outcome measures shed light on the destinationd theend, rather than the means. Outcome measures offer thepotential advantage of providing readouts on entirepopulations, rather than smaller population subsets, andthey focus on the “end results ”of care that are mostimportant to clinicians and pa tients.


Instruction: What do outcomes measure focus on?

Output: end results ”of care that are mostimportant to clinicians and pa tients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do outcomes measure focus on?. ### Response: end results ”of care that are mostimportant to clinicians and pa tients.


Instruction: What are the challenges withoutcome measures primarily in?

Output: risk-adjustmentmodeling methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the challenges withoutcome measures primarily in?. ### Response: risk-adjustmentmodeling methods.


Instruction: What can enhance the ability to compare outcomes across different delivery teams, settings, locations andsystems?

Output: risk-adjustmentmodeling methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can enhance the ability to compare outcomes across different delivery teams, settings, locations andsystems?. ### Response: risk-adjustmentmodeling methods.


Instruction: How many preferred attributes of model s have been described for outcomes that arepublicly reported?

Output: 7

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many preferred attributes of model s have been described for outcomes that arepublicly reported?. ### Response: 7.


Instruction: What should remain at the core of any performance measure that includes performance measures?

Output: model s used for outcomes that arepublicly reported

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should remain at the core of any performance measure that includes performance measures?. ### Response: model s used for outcomes that arepublicly reported.


Instruction: What should remain at the core of anyperformance measure that includes outcomes?

Output: model s used for outcomes that arepublicly reported

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should remain at the core of anyperformance measure that includes outcomes?. ### Response: model s used for outcomes that arepublicly reported.


Instruction: What are the Preferred Attributes of Models Used forPublicly Reported Outcomes?

Output: 1. Clear and explicit deﬁnition of an appropriate patient sample

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Preferred Attributes of Models Used forPublicly Reported Outcomes?. ### Response: 1. Clear and explicit deﬁnition of an appropriate patient sample.


Instruction: What should be used before and after covariates are derived?

Output: an appropriate reference time

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be used before and after covariates are derived?. ### Response: an appropriate reference time.


Instruction: What should use an appropriate outcome and a standardized period of outcome assessment?

Output: 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should use an appropriate outcome and a standardized period of outcome assessment?. ### Response: 5.


Instruction: Application of an analytical approach that takes into account what?

Output: themultilevel organization of data

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Application of an analytical approach that takes into account what?. ### Response: themultilevel organization of data.


Instruction: What are some of the methods used to compare outcomes?

Output: disclosure of performance or risk-adjustment methodology in derivationand validation samples

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the methods used to compare outcomes?. ### Response: disclosure of performance or risk-adjustment methodology in derivationand validation samples.


Instruction: Who gave permission to reproduce this article?

Output: Krumholz et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who gave permission to reproduce this article?. ### Response: Krumholz et al.


Instruction: What is the name of the journal in which this article was published?

Output: JACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal in which this article was published?. ### Response: JACC.


Instruction: What is the name of the patient who underwent Valve Surgery?

Output: Graboys TB, Cohn PF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the patient who underwent Valve Surgery?. ### Response: Graboys TB, Cohn PF.


Instruction: What is Graboys TB, Cohn PF's affiliation with?

Output: angina pectoris and abnormal coronary arteriograms in severe aortic valvular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Graboys TB, Cohn PF's affiliation with?. ### Response: angina pectoris and abnormal coronary arteriograms in severe aortic valvular disease.


Instruction: When was angina pectoris and abnormal coronary arteriograms found in severe aortic valvular disease?

Output: 1977

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was angina pectoris and abnormal coronary arteriograms found in severe aortic valvular disease?. ### Response: 1977.


Instruction: What is coronary artery disease in patients with valvular disease?

Output: coronary risk factors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is coronary artery disease in patients with valvular disease?. ### Response: coronary risk factors.


Instruction: What is the name of the prospective study?

Output: Ramsdale DR, Bennett DH, Bray CL, et al. Angina, coronary risk factors and coronary artery disease in patients with valvular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective study?. ### Response: Ramsdale DR, Bennett DH, Bray CL, et al. Angina, coronary risk factors and coronary artery disease in patients with valvular disease.


Instruction: When was this study published?

Output: April 27, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this study published?. ### Response: April 27, 2023.


Instruction: What is the European Journal of Heart Failure 7(3):393 -403 215?

Output: depressio n

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the European Journal of Heart Failure 7(3):393 -403 215?. ### Response: depressio n.


Instruction: What are the results of the ATLAS trial?

Output: Toleration of high doses of angiotensin -converting enzyme inhibitors in patients with chronic heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the ATLAS trial?. ### Response: Toleration of high doses of angiotensin -converting enzyme inhibitors in patients with chronic heart failure.


Instruction: What did the ATLAS trial show about heart failure?

Output: Toleration of high doses of angiotensin -converting enzyme inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the ATLAS trial show about heart failure?. ### Response: Toleration of high doses of angiotensin -converting enzyme inhibitors.


Instruction: What is the name of the study that evaluated the effectiveness of Lisinopril and survival?

Output: ATLAS trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated the effectiveness of Lisinopril and survival?. ### Response: ATLAS trial.


Instruction: When did the Archives of Internal Medicine issue 161(2):165-71 216?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Archives of Internal Medicine issue 161(2):165-71 216?. ### Response: 2001.


Instruction: What is the Seattle Heart Failure Model based on?

Output: community -based heart failure population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Seattle Heart Failure Model based on?. ### Response: community -based heart failure population.


Instruction: What is added to the model to enhance it?

Output: B -type natriuretic peptide

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is added to the model to enhance it?. ### Response: B -type natriuretic peptide.


Instruction: When did McDonald K, Ledwidge M, Kelly J, Quigley P, Maurer B, and McDonald K publish their findings?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did McDonald K, Ledwidge M, Kelly J, Quigley P, Maurer B, and McDonald K publish their findings?. ### Response: 2007.


Instruction: What did P, Maurer B, et al. find in a randomized, controlled trial of multidisciplinary care?

Output: Elimination of early rehosp italization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did P, Maurer B, et al. find in a randomized, controlled trial of multidisciplinary care?. ### Response: Elimination of early rehosp italization.


Instruction: What was the potential contribution of specialist care, clinical stability and clinical stability?

Output: Elimination of early rehosp italization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the potential contribution of specialist care, clinical stability and clinical stability?. ### Response: Elimination of early rehosp italization.


Instruction: What are measures at rest?

Output: Int J Cardiol. 2001;81:131–7. 11. Skalski J, Allison TG, Miller TD. The safety of cardiopulmonary exercise testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are measures at rest?. ### Response: Int J Cardiol. 2001;81:131–7. 11. Skalski J, Allison TG, Miller TD. The safety of cardiopulmonary exercise testing.


Instruction: What is the safety of cardiopulmonary exercise testing in a population with high-risk cardiovascular diseases?

Output: safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the safety of cardiopulmonary exercise testing in a population with high-risk cardiovascular diseases?. ### Response: safety.


Instruction: What is symptom-limited car -diopulmonary exercise testing in patients with aortic stenosis?

Output: Safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is symptom-limited car -diopulmonary exercise testing in patients with aortic stenosis?. ### Response: Safety.


Instruction: What is the name of the mendelian randomization study that compared systolic blood pressure and risk of valvular heart disease?

Output: JAMA Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the mendelian randomization study that compared systolic blood pressure and risk of valvular heart disease?. ### Response: JAMA Cardiol.


Instruction: How many people in the UK have aortic valve disease?

Output: 5.4 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people in the UK have aortic valve disease?. ### Response: 5.4 million.


Instruction: What is the name of the study that analyzed 5.4 million adults?

Output: Elevated blood pressure and risk of aortic valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that analyzed 5.4 million adults?. ### Response: Elevated blood pressure and risk of aortic valve disease.


Instruction: How many adults in the United Kingdom have arteries?

Output: 5.4 million

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many adults in the United Kingdom have arteries?. ### Response: 5.4 million.


Instruction: Who is the author?

Output: Chockalingam A, Venkatesan S, Subramaniam T, et al. Safety and efficacy of angiotensin-converting enzyme inhibitors in symptomatic severe aortic stenosis: Symptomatic Cardiac Obstruction-Pilot Study of Enalapril in Aor -tic Stenosis (SCOPE-AS). Am Heart J. 2004;147:E19. 11. Nadir MA, Wei L, Elder DHJ, et al. Impact of renin-angiotensin system blockade therapy on outcome in aortic stenosis. J Am Coll Cardiol. 2011;58:570–6. 12. Rieck ÅE, Cramariuc D, Boman K, et al. Hypertension in aortic stenosis: implications for left ventricular structure and cardiovascular events. Hyper -tension. 2012;60:90–7. 13. Briand M, D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author?. ### Response: Chockalingam A, Venkatesan S, Subramaniam T, et al. Safety and efficacy of angiotensin-converting enzyme inhibitors in symptomatic severe aortic stenosis: Symptomatic Cardiac Obstruction-Pilot Study of Enalapril in Aor -tic Stenosis (SCOPE-AS). Am Heart J. 2004;147:E19. 11. Nadir MA, Wei L, Elder DHJ, et al. Impact of renin-angiotensin system blockade therapy on outcome in aortic stenosis. J Am Coll Cardiol. 2011;58:570–6. 12. Rieck ÅE, Cramariuc D, Boman K, et al. Hypertension in aortic stenosis: implications for left ventricular structure and cardiovascular events. Hyper -tension. 2012;60:90–7. 13. Briand M, D.


Instruction: What study assessed optimal blood pressure in patients with asymptomatic aortic valve stenosis?

Output: Simvastatin Ezetimibe in Aortic Stenosis study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study assessed optimal blood pressure in patients with asymptomatic aortic valve stenosis?. ### Response: Simvastatin Ezetimibe in Aortic Stenosis study.


Instruction: What is the acronym for the Simvastatin Ezetimibe in Aortic Stenosis study?

Output: SEAS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Simvastatin Ezetimibe in Aortic Stenosis study?. ### Response: SEAS.


Instruction: In what year did Circulation issue 134:455-6?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Circulation issue 134:455-6?. ### Response: 2016.


Instruction: What is stenosis?

Output: asymptomatic aortic valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stenosis?. ### Response: asymptomatic aortic valve.


Instruction: What is the name of the randomized trial of inten-sive lipid-lowering therapy?

Output: Simvastatin Ezetimibe in Aortic Stenosis study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of inten-sive lipid-lowering therapy?. ### Response: Simvastatin Ezetimibe in Aortic Stenosis study.


Instruction: How does rosuvas-tatin affect progression of aortic disease?

Output: Effect of lipid lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does rosuvas-tatin affect progression of aortic disease?. ### Response: Effect of lipid lowering.


Instruction: What is rosuvas-tatin used for?

Output: Intensive lipid lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rosuvas-tatin used for?. ### Response: Intensive lipid lowering.


Instruction: What is the name of the ASTRONOMER trial?

Output: Aortic Stenosis Pro-gression Observation: Measuring Effects Of Rosuvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ASTRONOMER trial?. ### Response: Aortic Stenosis Pro-gression Observation: Measuring Effects Of Rosuvastatin.


Instruction: When was the Aortic Stenosis Progression Observation: Measuring Effects Of Rosuvastatin conducted?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Aortic Stenosis Progression Observation: Measuring Effects Of Rosuvastatin conducted?. ### Response: 2010.


Instruction: What is the name of the procedure used to implant a transcatheter aortic valve?

Output: Renin-angiotensin system block-ade therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure used to implant a transcatheter aortic valve?. ### Response: Renin-angiotensin system block-ade therapy.


Instruction: What are the results of a renin-angiotensin inhibitor treatment?

Output: mortality and heart failure readmission

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of a renin-angiotensin inhibitor treatment?. ### Response: mortality and heart failure readmission.


Instruction: What is ramipril?

Output: angiotensin-converting enzyme inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ramipril?. ### Response: angiotensin-converting enzyme inhibitor.


Instruction: What is the name of the angiotensin-converting enzyme inhibitor in patients with mild to moderate aortic stenosis and preserved left ventricular function?

Output: ramipril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the angiotensin-converting enzyme inhibitor in patients with mild to moderate aortic stenosis and preserved left ventricular function?. ### Response: ramipril.


Instruction: In what year did J Investig Med publish a report on the safety and efficacy of angioensin conversion enzyme inhibitors?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did J Investig Med publish a report on the safety and efficacy of angioensin conversion enzyme inhibitors?. ### Response: 2004.


Instruction: What is SCOPE-AS?

Output: Symptomatic Cardiac Obstruction-Pilot Study of Enalapril in Aor -tic Stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is SCOPE-AS?. ### Response: Symptomatic Cardiac Obstruction-Pilot Study of Enalapril in Aor -tic Stenosis.


Instruction: What is the name of the symptomatic Cardiac Obstruction-Pilot Study of Enalapril in Aortic Stenosis?

Output: SCOPE-AS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the symptomatic Cardiac Obstruction-Pilot Study of Enalapril in Aortic Stenosis?. ### Response: SCOPE-AS.


Instruction: What is the effect of therapy on outcome in aortic stenosis?

Output: Intensive lipid lowering

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of therapy on outcome in aortic stenosis?. ### Response: Intensive lipid lowering.


Instruction: What is Rieck E, Cramariuc D, Boman K, et al. Hypertension and left ventricular structure are implications for what?

Output: cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Rieck E, Cramariuc D, Boman K, et al. Hypertension and left ventricular structure are implications for what?. ### Response: cardiovascular events.


Instruction: Kadem L, et al. Reduced systemic arterial compliance impacts significantly on left ventricular afterload and function in what?

Output: aor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kadem L, et al. Reduced systemic arterial compliance impacts significantly on left ventricular afterload and function in what?. ### Response: aor.


Instruction: How many cardiac troponin subunits are derived from genes specifically expressed in the myocardium?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cardiac troponin subunits are derived from genes specifically expressed in the myocardium?. ### Response: 2.


Instruction: The quality of included studies ranged from high to what?

Output: very low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The quality of included studies ranged from high to what?. ### Response: very low.


Instruction: Evidence was downgraded due to risk of bias and imprecision due to the range of the confidence interval around the point estimate?

Output: Evidence was downgraded due to risk of bias and imprecision due to the range of the confidence i nterval

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Evidence was downgraded due to risk of bias and imprecision due to the range of the confidence interval around the point estimate?. ### Response: Evidence was downgraded due to risk of bias and imprecision due to the range of the confidence i nterval.


Instruction: Why was the study downgraded?

Output: risk of bias and imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the study downgraded?. ### Response: risk of bias and imprecision.


Instruction: Why did the study fail to include results for people under 50 years of age?

Output: the authors felt as though the prevalence of HF in this group was low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did the study fail to include results for people under 50 years of age?. ### Response: the authors felt as though the prevalence of HF in this group was low.


Instruction: The authors felt that the prevalence of HF in this group was low?

Output: A single study was also downgraded due to indirectness as the study failed to include results for people under 50 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The authors felt that the prevalence of HF in this group was low?. ### Response: A single study was also downgraded due to indirectness as the study failed to include results for people under 50 years of age.


Instruction: A single high qualit y study reported a high sensitivity of what percentage?

Output: 100  (93-100)%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A single high qualit y study reported a high sensitivity of what percentage?. ### Response: 100  (93-100)%.


Instruction: How high was the sensitivity of NT-pro BNP?

Output: 100  (93-100)%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How high was the sensitivity of NT-pro BNP?. ### Response: 100  (93-100)%.


Instruction: What was the majority of the evidence for?

Output: NT -pro BNP was low quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the majority of the evidence for?. ### Response: NT -pro BNP was low quality.


Instruction: For women 50 years, a high s ensitivity was what?

Output: 100 (90 -100)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For women 50 years, a high s ensitivity was what?. ### Response: 100 (90 -100).


Instruction: What was the high s ensitivity of women 50 years?

Output: 100

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the high s ensitivity of women 50 years?. ### Response: 100.


Instruction: What threshold did the committee pre-select for possible recommendation?

Output: 67pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What threshold did the committee pre-select for possible recommendation?. ### Response: 67pg/ml.


Instruction: How high was the sensitivity of women at a threshold of 67pg/ml?

Output: 100 (90 -100)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How high was the sensitivity of women at a threshold of 67pg/ml?. ### Response: 100 (90 -100).


Instruction: What were the sensitivities for men 50 years?

Output: 100 (92 -100) and 96 (85 -99)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the sensitivities for men 50 years?. ### Response: 100 (92 -100) and 96 (85 -99).


Instruction: What was the threshold set by the FDA?

Output: 67pg/ml which met the sensitivity threshold pre specified by the committee for possible recommendation. For the same group at thresholds of 144pg/ml and 220pg/ml

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the threshold set by the FDA?. ### Response: 67pg/ml which met the sensitivity threshold pre specified by the committee for possible recommendation. For the same group at thresholds of 144pg/ml and 220pg/ml.


Instruction: How many mg/dl did both of these drugs meet the threshold set by the committee?

Output: 93

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg/dl did both of these drugs meet the threshold set by the committee?. ### Response: 93.


Instruction: What did a single study of high blood pressure do?

Output: downgraded

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a single study of high blood pressure do?. ### Response: downgraded.


Instruction: What is Gavin J Becker's profession?

Output: MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Gavin J Becker's profession?. ### Response: MD.


Instruction: What is the work group co-chair of Kidney International Supplements?

Output: Gavin J Becker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the work group co-chair of Kidney International Supplements?. ### Response: Gavin J Becker.


Instruction: Where does Gavin Becker work?

Output: RoyalMelbourne Hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does Gavin Becker work?. ### Response: RoyalMelbourne Hospital.


Instruction: Who is a Past President of the Asian Pacific Society ofNephrology?

Output: Gavin J Becker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Past President of the Asian Pacific Society ofNephrology?. ### Response: Gavin J Becker.


Instruction: How many papers has Dr Becker published?

Output: over 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many papers has Dr Becker published?. ### Response: over 300.


Instruction: How many chapters and books has Dr. Becker written?

Output: over 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many chapters and books has Dr. Becker written?. ### Response: over 300.


Instruction: Who is the Associate Editor for Nephrology Dialysis Transplantation?

Output: Dr Becker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Associate Editor for Nephrology Dialysis Transplantation?. ### Response: Dr Becker.


Instruction: What are his research interests focused on?

Output: progressionof kidney failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are his research interests focused on?. ### Response: progressionof kidney failure.


Instruction: What is the development of nephrology in the Asian Pacific?

Output: renal physician education

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the development of nephrology in the Asian Pacific?. ### Response: renal physician education.


Instruction: In what year was he awarded the International DistinguishedMedal by the US National Kidney Foundation?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was he awarded the International DistinguishedMedal by the US National Kidney Foundation?. ### Response: 2002.


Instruction: What honor did he receive from the CeylonCollege of Physicians in 2003?

Output: Honorary Fellowship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What honor did he receive from the CeylonCollege of Physicians in 2003?. ### Response: Honorary Fellowship.


Instruction: Who awarded him the Oshima Award from the Asian Pacific Society of Medicine?

Output: Asian Paciﬁc Society of Nephrology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who awarded him the Oshima Award from the Asian Pacific Society of Medicine?. ### Response: Asian Paciﬁc Society of Nephrology.


Instruction: When did the Asian Pacific Society of Nephrology award the Oshima Award?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Asian Pacific Society of Nephrology award the Oshima Award?. ### Response: 2005.


Instruction: When was the Chairman’s Best of Health Award given?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Chairman’s Best of Health Award given?. ### Response: 2002.


Instruction: Where does David Wheeler hold an academic position in Nephroology?

Output: University College London, UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does David Wheeler hold an academic position in Nephroology?. ### Response: University College London, UK.


Instruction: Where is Dr Wheeler an academic position in Nephrology (Reader)?

Output: University College London, UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Dr Wheeler an academic position in Nephrology (Reader)?. ### Response: University College London, UK.


Instruction: Where is he an Honorary Consultant Nephrologist?

Output: Royal Free Hospital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is he an Honorary Consultant Nephrologist?. ### Response: Royal Free Hospital.


Instruction: What is his research focused on?

Output: progressionof kidney failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is his research focused on?. ### Response: progressionof kidney failure.


Instruction: Who is a member of the InternationalSteering Committee of the Study of Heart and RenalProtection (SHARP)?

Output: Dr Wheeler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the InternationalSteering Committee of the Study of Heart and RenalProtection (SHARP)?. ### Response: Dr Wheeler.


Instruction: What was the UK National Coordinator for?

Output: the trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the UK National Coordinator for?. ### Response: the trial.


Instruction: Who is Co-Chair of KDIGO?

Output: Dr Wheeler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Co-Chair of KDIGO?. ### Response: Dr Wheeler.


Instruction: Who was awarded an International Distinguished Medal from the US National Kidney Foundation?

Output: Dr Wheeler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was awarded an International Distinguished Medal from the US National Kidney Foundation?. ### Response: Dr Wheeler.


Instruction: Who was elected President of the Renal Association for the term 2012-2014?

Output: Dr Wheeler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was elected President of the Renal Association for the term 2012-2014?. ### Response: Dr Wheeler.


Instruction: How long has Dr. Wheeler served on the editorial boards of KDIGO?

Output: previously

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has Dr. Wheeler served on the editorial boards of KDIGO?. ### Response: previously.


Instruction: Who is currently Co-Editor of NephrologyDialysis Transplantation?

Output: Dr Wheeler

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is currently Co-Editor of NephrologyDialysis Transplantation?. ### Response: Dr Wheeler.


Instruction: Who is the Advisor/Consultant?

Output: Amgen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Advisor/Consultant?. ### Response: Amgen.


Instruction: What is the Travel Stipend?

Output: Amgen; Merck Sharp & Dohme; Shire

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Travel Stipend?. ### Response: Amgen; Merck Sharp & Dohme; Shire.


Instruction: What is Chlorthalidone and Hydrochlorothiazide used for in hypertension patients?

Output: treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Chlorthalidone and Hydrochlorothiazide used for in hypertension patients?. ### Response: treatment.


Instruction: What is the JAMAIntern Med. 2020;180:1132 - 1133.175.

Output: Chlorthalidone andhydrochlorothiazide for treatment of patients with hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the JAMAIntern Med. 2020;180:1132 - 1133.175.. ### Response: Chlorthalidone andhydrochlorothiazide for treatment of patients with hypertension.


Instruction: What type of diuretics are used in heart failure?

Output: loop diureticswith thiazide-type

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diuretics are used in heart failure?. ### Response: loop diureticswith thiazide-type.


Instruction: What is the name of the group that studies the effect of ramipril on decline?

Output: GISEN Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studies the effect of ramipril on decline?. ### Response: GISEN Group.


Instruction: What is a placebo-controlled trial?

Output: Randomised placebo-controlled trial of effect of ramipril on decline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a placebo-controlled trial?. ### Response: Randomised placebo-controlled trial of effect of ramipril on decline.


Instruction: Aspirin,253,254,263,264 and the absence of data from RCTs demonstrating superior efficacy of higher aspirin doses in this setting?

Output: 259

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Aspirin,253,254,263,264 and the absence of data from RCTs demonstrating superior efficacy of higher aspirin doses in this setting?. ### Response: 259.


Instruction: Because the CURRENT-OASIS 7 trial did not report differences in what?

Output: efficacy or safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Because the CURRENT-OASIS 7 trial did not report differences in what?. ### Response: efficacy or safety.


Instruction: How many mg of aspirin did the trial report in STEMI patients?

Output: 325

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg of aspirin did the trial report in STEMI patients?. ### Response: 325.


Instruction: What did the committee not think the evi-dence favoring 81 mg over higher dosages was sufficient to merit a Class I recommendation?

Output: conclusive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee not think the evi-dence favoring 81 mg over higher dosages was sufficient to merit a Class I recommendation?. ### Response: conclusive.


Instruction: What is provided before or at the time of primary PCI?

Output: Loading doses of P2Y12 inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is provided before or at the time of primary PCI?. ### Response: Loading doses of P2Y12 inhibitors.


Instruction: How long are P2Y12 inhibitors continued in a maintenance dose after PCI with a stent?

Output: 1 year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long are P2Y12 inhibitors continued in a maintenance dose after PCI with a stent?. ### Response: 1 year.


Instruction: What is a 600-mg loading dose of clopidogrel?

Output: 300-mg loading dose

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 600-mg loading dose of clopidogrel?. ### Response: 300-mg loading dose.


Instruction: What is the preferred loading dose of clopidogrel to a 300-mg loading dose?

Output: 600-mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preferred loading dose of clopidogrel to a 300-mg loading dose?. ### Response: 600-mg.


Instruction: What is ARMYDA-6 MI?

Output: Antiplatelet Therapy for Reduction of Myocardial Damage During Angioplasty–Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ARMYDA-6 MI?. ### Response: Antiplatelet Therapy for Reduction of Myocardial Damage During Angioplasty–Myocardial Infarction.


Instruction: How many subgroups did the ARMYDA-6 MI study have?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many subgroups did the ARMYDA-6 MI study have?. ### Response: 3.


Instruction: What is the name of the drug that was used to reduce myocardial damage during angioplasty?

Output: ARMYDA-6 MI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that was used to reduce myocardial damage during angioplasty?. ### Response: ARMYDA-6 MI.


Instruction: The higher the clopidogrel loading dose, the better what?

Output: surrogate outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The higher the clopidogrel loading dose, the better what?. ### Response: surrogate outcomes.


Instruction: What percentage of patients may harbor a reduced-function CYP2C19 allele?

Output: 25% to 30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients may harbor a reduced-function CYP2C19 allele?. ### Response: 25% to 30%.