Instruction: What does Manning L, Robinson TG, Anderson CS do in hypertensive neurological emergencies?

Output: Control of blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Manning L, Robinson TG, Anderson CS do in hypertensive neurological emergencies?. ### Response: Control of blood pressure.


Instruction: How does Rhoney D, Peacock WF treat hypertension?

Output: Intravenous therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does Rhoney D, Peacock WF treat hypertension?. ### Response: Intravenous therapy.


Instruction: What is the name of the part 1 of Intravenous therapy for hyperten-sive emergencies?

Output: S11.2-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the part 1 of Intravenous therapy for hyperten-sive emergencies?. ### Response: S11.2-1.


Instruction: What are some different types of essential hypertension: their course and prognosis?

Output: pertensive Crises—Emergencies  and Urgencies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some different types of essential hypertension: their course and prognosis?. ### Response: pertensive Crises—Emergencies  and Urgencies.


Instruction: What is essential hypertension: their course and prognosis?

Output: Some different types

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is essential hypertension: their course and prognosis?. ### Response: Some different types.


Instruction: What is the name of the systematic review of pharmacological interventions for hyperten-sive emergencies?

Output: Cochrane

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of pharmacological interventions for hyperten-sive emergencies?. ### Response: Cochrane.


Instruction: What is used in hypertensive emergencies?

Output: sodium nitroprusside

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used in hypertensive emergencies?. ### Response: sodium nitroprusside.


Instruction: What is the name of the randomized trial of IV nicardipine versus labetalol in the emergency department?

Output: CLUE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of IV nicardipine versus labetalol in the emergency department?. ### Response: CLUE.


Instruction: Bozkurt et alDecember 6, 2016 Circulation. 2016;134:e535–e578 What is the DOI: 10.1161/CIR.0000000000000450 e568 49?

Output: 106

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bozkurt et alDecember 6, 2016 Circulation. 2016;134:e535–e578 What is the DOI: 10.1161/CIR.0000000000000450 e568 49?. ### Response: 106.


Instruction: What is the effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarc-tion?

Output: reverses left ventricular remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarc-tion?. ### Response: reverses left ventricular remodeling.


Instruction: What are the results of the survival and ventricular enlargement trial called?

Output: SAVE Investi-gators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the survival and ventricular enlargement trial called?. ### Response: SAVE Investi-gators.


Instruction: What is the name of the study that examined the effects of enalapril on mortality in severe congestive heart failure?

Output: Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS): the CONSENSUS Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the effects of enalapril on mortality in severe congestive heart failure?. ### Response: Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS): the CONSENSUS Trial.


Instruction: What is CONSENSUS?

Output: Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS): the CONSENSUS Trial Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CONSENSUS?. ### Response: Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS): the CONSENSUS Trial Study Group.


Instruction: When was the CONSENTUS Trial Study Group conducted?

Output: 1987

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the CONSENTUS Trial Study Group conducted?. ### Response: 1987.


Instruction: What did the SOLVD Investigators study?

Output: the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the SOLVD Investigators study?. ### Response: the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions.


Instruction: What did N Engl J Med. 1992:327:1768 say about heart failure?

Output: 685–691

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did N Engl J Med. 1992:327:1768 say about heart failure?. ### Response: 685–691.


Instruction: How many people participated in the network meta-analysis?

Output: more than 65,000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people participated in the network meta-analysis?. ### Response: more than 65,000.


Instruction: What is the name of the randomised trial in which carvedilol was used?

Output: CAPRICORN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial in which carvedilol was used?. ### Response: CAPRICORN.


Instruction: What is the name of the randomised trial in patients with left-ventricular dysfunction?

Output: CAPRICORN

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial in patients with left-ventricular dysfunction?. ### Response: CAPRICORN.


Instruction: What is one of the benefits of beta-blockers to angiotensin-converting enzyme inhibitors in the SAVE Study?

Output: Additive beneficial effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the benefits of beta-blockers to angiotensin-converting enzyme inhibitors in the SAVE Study?. ### Response: Additive beneficial effects.


Instruction: What is the acronym for the Survival and Ventricular Enlargement Study?

Output: SAVE Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Survival and Ventricular Enlargement Study?. ### Response: SAVE Investigators.


Instruction: When was the SAVE Study published?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the SAVE Study published?. ### Response: 1997.


Instruction: What was the name of the study?

Output: REVERT Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study?. ### Response: REVERT Study Group.


Instruction: What is a post hoc analysis of the Studies of Left Ventricular Dysfunction?

Output: Beta-adrenergic blocking agent use and mortality in patients with as-ymptomatic and symptomatic left ventricular systolic dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a post hoc analysis of the Studies of Left Ventricular Dysfunction?. ### Response: Beta-adrenergic blocking agent use and mortality in patients with as-ymptomatic and symptomatic left ventricular systolic dysfunction.


Instruction: When did J Am Coll Cardiol issue 33:916-923?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol issue 33:916-923?. ### Response: 1999.


Instruction: What is the effect of enalapril on 12-year survival and life expectancy in patients with left ventricular systolic dysfunction?

Output: reverses left ventricular remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of enalapril on 12-year survival and life expectancy in patients with left ventricular systolic dysfunction?. ### Response: reverses left ventricular remodeling.


Instruction: What is the name of the follow-up study on left ventricular systolic dysfunction?

Output: REVERT Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the follow-up study on left ventricular systolic dysfunction?. ### Response: REVERT Study Group.


Instruction: What does Metoprolol reverse?

Output: left ventricular remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Metoprolol reverse?. ### Response: left ventricular remodeling.


Instruction: What is the name of the REversal of VEntricular Remodeling with Toprol-XL trial?

Output: REVERT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the REversal of VEntricular Remodeling with Toprol-XL trial?. ### Response: REVERT.


Instruction: When did Circulation. 2007:116:49-56. doi: 10.1161/CIRCULATIONAHA.106.666016.

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation. 2007:116:49-56. doi: 10.1161/CIRCULATIONAHA.106.666016.. ### Response: 2007.


Instruction: What is asymptomatic systolic dysfunction?

Output: left ventricular remodeling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is asymptomatic systolic dysfunction?. ### Response: left ventricular remodeling.


Instruction: What are some of the causes of chronic elevations?

Output: structural cardiac abnormalities such as LV hypertrophy or ventricular dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the causes of chronic elevations?. ### Response: structural cardiac abnormalities such as LV hypertrophy or ventricular dilatation.


Instruction: Patients with end-stage renal disease and no clini-cal evidence of ACS often have elevations of what?

Output: cardiac tropo-nin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with end-stage renal disease and no clini-cal evidence of ACS often have elevations of what?. ### Response: cardiac tropo-nin.


Instruction: What is a structural cardiac abnormality that can cause chronic elevation?

Output: LV hypertrophy or ventricular dilatation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a structural cardiac abnormality that can cause chronic elevation?. ### Response: LV hypertrophy or ventricular dilatation.


Instruction: What does no clini-cal evidence of ACS frequently have elevations of?

Output: cardiac tropo-nin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does no clini-cal evidence of ACS frequently have elevations of?. ### Response: cardiac tropo-nin.


Instruction: What is more common with conventional assays than with cardiac troponin I?

Output: CK-MB and myoglobin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is more common with conventional assays than with cardiac troponin I?. ### Response: CK-MB and myoglobin.


Instruction: In the diagnosis of NSTEMI, what must manifest an acute pattern consistent with clinical events?

Output: cardiac troponin values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the diagnosis of NSTEMI, what must manifest an acute pattern consistent with clinical events?. ### Response: cardiac troponin values.


Instruction: What may persist for up to 14 days or sometimes longer?

Output: Troponin elevations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may persist for up to 14 days or sometimes longer?. ### Response: Troponin elevations.


Instruction: There is a paucity of guidelines for establishment of reinfarction during the acute infarct period on the basis of what?

Output: troponin measurements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is a paucity of guidelines for establishment of reinfarction during the acute infarct period on the basis of what?. ### Response: troponin measurements.


Instruction: What is the basis of troponin measurements?

Output: electrocardiographic changes and/or intermediate/high risk clinical featuresI A 21, 72–74, 157Consider time of presentation the time of onset with ambiguous symptom onset

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the basis of troponin measurements?. ### Response: electrocardiographic changes and/or intermediate/high risk clinical featuresI A 21, 72–74, 157Consider time of presentation the time of onset with ambiguous symptom onset.


Instruction: What may indicate a reinfarction?

Output: an increase of >20% of previous troponin levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may indicate a reinfarction?. ### Response: an increase of >20% of previous troponin levels.


Instruction: During pregnancy, what is within the normal range in the absence of cardiovascular morbidities?

Output: troponin values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: During pregnancy, what is within the normal range in the absence of cardiovascular morbidities?. ### Response: troponin values.


Instruction: What do cardiac troponin elevations reflect when present?

Output: myocardial necrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do cardiac troponin elevations reflect when present?. ### Response: myocardial necrosis.


Instruction: What may provide initial diagnostic information?

Output: Point-of-care troponin values

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may provide initial diagnostic information?. ### Response: Point-of-care troponin values.


Instruction: What is the sensitivity of troponin elevations below that of central laboratory methods?

Output: substantially

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the sensitivity of troponin elevations below that of central laboratory methods?. ### Response: substantially.


Instruction: What type of standardization is needed for routine diagnosis?

Output: rigorous quantitative assay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of standardization is needed for routine diagnosis?. ### Response: rigorous quantitative assay.


Instruction: What may provide infor-mation to direct therapy?

Output: troponin elevations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may provide infor-mation to direct therapy?. ### Response: troponin elevations.


Instruction: What is the name of the test used to determine cardiac troponin elevations?

Output: predischarge stress test

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the test used to determine cardiac troponin elevations?. ### Response: predischarge stress test.


Instruction: How long after symptom onset do patients with suspected ACS need to obtain additional troponin levels?

Output: 3–6 h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after symptom onset do patients with suspected ACS need to obtain additional troponin levels?. ### Response: 3–6 h.


Instruction: What is the name of the drug used to identify pattern of values in patients with ACS?

Output: cardiac-specific troponin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to identify pattern of values in patients with ACS?. ### Response: cardiac-specific troponin.


Instruction: In patients with electrocardiographic changes and/or intermediate/high risk clinical features, what is the term used to describe the amount of the initial normal serial tropins?

Output: troponin levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with electrocardiographic changes and/or intermediate/high risk clinical features, what is the term used to describe the amount of the initial normal serial tropins?. ### Response: troponin levels.


Instruction: What are troponins with electrocardiographic changes and/or intermediate/high risk clinical features?

Output: ischemic symp-toms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are troponins with electrocardiographic changes and/or intermediate/high risk clinical features?. ### Response: ischemic symp-toms.


Instruction: What are not useful for diagnosis of ACS III: No Benefit?

Output: CK-MB and myoglobin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are not useful for diagnosis of ACS III: No Benefit?. ### Response: CK-MB and myoglobin.


Instruction: What is useful for diagnosis of ACS III: No Benefit A 158–164PrognosisTroponin elevations are useful for what?

Output: short- and long-term prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful for diagnosis of ACS III: No Benefit A 158–164PrognosisTroponin elevations are useful for what?. ### Response: short- and long-term prognosis.


Instruction: Measurement of troponin value once on d 3 or 4 in patients with MI may be reasonable as an indication?

Output: Point-of-care troponin values may provide initial diagnostic information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Measurement of troponin value once on d 3 or 4 in patients with MI may be reasonable as an indication?. ### Response: Point-of-care troponin values may provide initial diagnostic information.


Instruction: How long postoperative survival is 20% in CCTGA patients referred for TVR?

Output: 10-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long postoperative survival is 20% in CCTGA patients referred for TVR?. ### Response: 10-year.


Instruction: What is the preoperative sys-temic ventricular ejection fraction?

Output: <40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preoperative sys-temic ventricular ejection fraction?. ### Response: <40%.


Instruction: How many CCTGA patients were referred for TR surgery?

Output: 46

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many CCTGA patients were referred for TR surgery?. ### Response: 46.


Instruction: What was the only independent predictor of postoperative sys-temic ventricular ejection fraction at 1 year?

Output: preoper -ative systemic ventricular ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the only independent predictor of postoperative sys-temic ventricular ejection fraction at 1 year?. ### Response: preoper -ative systemic ventricular ejection fraction.


Instruction: What was often managed in childhood by plac-ing a conduit from the morphologic LV to the PA?

Output: Adults with CCTGA and pulmonary atresia or ste-nosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was often managed in childhood by plac-ing a conduit from the morphologic LV to the PA?. ### Response: Adults with CCTGA and pulmonary atresia or ste-nosis.


Instruction: What is common?

Output: progressive conduit dysfunction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is common?. ### Response: progressive conduit dysfunction.


Instruction: Conduit intervention or replacement will diminish the pressure in what?

Output: subpulmonic ventricle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Conduit intervention or replacement will diminish the pressure in what?. ### Response: subpulmonic ventricle.


Instruction: Where does ventricular septal shift toward?

Output: subpulmonic left ventricle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where does ventricular septal shift toward?. ### Response: subpulmonic left ventricle.


Instruction: What can result in worsening of TR and a detrimental impact on systemic RV function?

Output: ricular septal shift toward the subpulmonic left ventricle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can result in worsening of TR and a detrimental impact on systemic RV function?. ### Response: ricular septal shift toward the subpulmonic left ventricle.


Instruction: Fontan Palliation of Single Ventricle Physiology includes Tricuspid Atresia and what other condition?

Output: Double Inlet Left Ventricle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Fontan Palliation of Single Ventricle Physiology includes Tricuspid Atresia and what other condition?. ### Response: Double Inlet Left Ventricle.


Instruction: What should be managed promptly in adults with Fontan palliation?

Output: New presentation of an atrial tachyarrhythmia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be managed promptly in adults with Fontan palliation?. ### Response: New presentation of an atrial tachyarrhythmia.


Instruction: What should include prevention of thromboembolic events?

Output: New presentation of an atrial tachyarrhythmia in adults with Fontan palliation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should include prevention of thromboembolic events?. ### Response: New presentation of an atrial tachyarrhythmia in adults with Fontan palliation.


Instruction: What should be managed promptly and include prevention of thromboembolic events and consultation with an electrophysiologist with CHD expertise?

Output: New presentation of an atrial tachyarrhythmia in adults with Fontan palliation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be managed promptly and include prevention of thromboembolic events and consultation with an electrophysiologist with CHD expertise?. ### Response: New presentation of an atrial tachyarrhythmia in adults with Fontan palliation.


Instruction: Adults after Fontan palliation should be evaluated annually with either echocardiography or CMR.

Output: I C-EO3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adults after Fontan palliation should be evaluated annually with either echocardiography or CMR.. ### Response: I C-EO3.


Instruction: What should be performed in adults before initial Fontan surgery or revision of a prior Fontan connection to assess suitability of preintervention hemodynamics for Fontan physiology?

Output: Cardiac catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed in adults before initial Fontan surgery or revision of a prior Fontan connection to assess suitability of preintervention hemodynamics for Fontan physiology?. ### Response: Cardiac catheterization.


Instruction: What should adults with single ventricle after Fontan palliation prompt a search for?

Output: potential hemodynamic abnormalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should adults with single ventricle after Fontan palliation prompt a search for?. ### Response: potential hemodynamic abnormalities.


Instruction: What may necessitate imaging and/or cardiac catheterization?

Output: New onset or worsening atrial tachyarrhythmias in adults with single ventricle after Fontan palliation should prompt a search for potential hemodynamic abnormalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may necessitate imaging and/or cardiac catheterization?. ### Response: New onset or worsening atrial tachyarrhythmias in adults with single ventricle after Fontan palliation should prompt a search for potential hemodynamic abnormalities.


Instruction: What is reasonable in adults after Fontan palliation?

Output: encourage a regular  exercise program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable in adults after Fontan palliation?. ### Response: encourage a regular  exercise program.


Instruction: What are imaging of the liver and laboratory evaluation of liver function?

Output: ultrasonography, CMR, CT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are imaging of the liver and laboratory evaluation of liver function?. ### Response: ultrasonography, CMR, CT.


Instruction: What is a good reason to perform biochemical and hematological testing on an annual basis?

Output: liver and renal function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a good reason to perform biochemical and hematological testing on an annual basis?. ### Response: liver and renal function.


Instruction: What is useful to evaluate a symptomatic adult after Fontana?

Output: Cardiac catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful to evaluate a symptomatic adult after Fontana?. ### Response: Cardiac catheterization.


Instruction: Why is there increasing interest in the development of cath-eter-based therapies for right-sided HF?

Output: an increasing number of patients pre-senting with right-sided HF from isolated TR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there increasing interest in the development of cath-eter-based therapies for right-sided HF?. ### Response: an increasing number of patients pre-senting with right-sided HF from isolated TR.


Instruction: What is the result of better surgical techniques?

Output: lower operative risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the result of better surgical techniques?. ### Response: lower operative risk.


Instruction: What should be addressed as part of the treatment of severe TR?

Output: reduction of RV afterload

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be addressed as part of the treatment of severe TR?. ### Response: reduction of RV afterload.


Instruction: What may not improve predictably after treatment of the lesion?

Output: Severe TR of either a primary or secondary etiol-ogy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not improve predictably after treatment of the lesion?. ### Response: Severe TR of either a primary or secondary etiol-ogy.


Instruction: What should be addressed as part of the index procedure?

Output: severe TR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be addressed as part of the index procedure?. ### Response: severe TR.


Instruction: Reoperation for severe, isolated TR after left-sided valve surgery is associated with a perioperative mortality rate of what?

Output: 10% to 25%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Reoperation for severe, isolated TR after left-sided valve surgery is associated with a perioperative mortality rate of what?. ### Response: 10% to 25%..


Instruction: What does not add appreciably to the risks of surgery?

Output: Tricuspid valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does not add appreciably to the risks of surgery?. ### Response: Tricuspid valve repair.


Instruction: What has been a significant increase in the number of tricuspid valve repairs over the past decade?

Output: There has been a significant increase in the number of tricuspid valve repairs performed for this indica-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been a significant increase in the number of tricuspid valve repairs over the past decade?. ### Response: There has been a significant increase in the number of tricuspid valve repairs performed for this indica-tion.


Instruction: Tricuspid valve repair is preferable to what?

Output: replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Tricuspid valve repair is preferable to what?. ### Response: replacement.


Instruction: Is marked dilation of the annulus or intrinsic disease of the tricuspid leaf-lets?

Output: intrinsic disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Is marked dilation of the annulus or intrinsic disease of the tricuspid leaf-lets?. ### Response: intrinsic disease.


Instruction: Observational data have shown a lower operative risk with what?

Output: tricuspid valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Observational data have shown a lower operative risk with what?. ### Response: tricuspid valve repair.


Instruction: What may be related to patient selection?

Output: better selection processes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be related to patient selection?. ### Response: better selection processes.


Instruction: What would be inserted in patients with a severely dilated annulus and abnormal leaflets to prevent recurrent or residual regurgitation?

Output: tricuspid valve repair

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be inserted in patients with a severely dilated annulus and abnormal leaflets to prevent recurrent or residual regurgitation?. ### Response: tricuspid valve repair.


Instruction: The risks and benefits of tricuspid valve operation should be carefully considered in the presence of severe RV systolic dysfunction or irreversible pulmonary hypertension?

Output: possibility of RV failure after operation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The risks and benefits of tricuspid valve operation should be carefully considered in the presence of severe RV systolic dysfunction or irreversible pulmonary hypertension?. ### Response: possibility of RV failure after operation.


Instruction: What is the risk of irreversible pulmonary hypertension after an operation?

Output: RV failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of irreversible pulmonary hypertension after an operation?. ### Response: RV failure.


Instruction: What percentage of patients have mild or moderate degrees of second-ary TR?

Output: 25%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients have mild or moderate degrees of second-ary TR?. ### Response: 25%.


Instruction: What are risk factors for persistence or progression of TR?

Output: tricuspid annulus dilation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are risk factors for persistence or progression of TR?. ### Response: tricuspid annulus dilation.


Instruction: What is the diameter of tricuspid annulus dilation indexed to body surface area on pre-operative TTE measured at end diastole?

Output: >70

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diameter of tricuspid annulus dilation indexed to body surface area on pre-operative TTE measured at end diastole?. ### Response: >70.


Instruction: How much diameter on direct intraoperative measure-ment of intercomissural distance?

Output: >70 mm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much diameter on direct intraoperative measure-ment of intercomissural distance?. ### Response: >70 mm.


Instruction: What is the diameter on direct intraoperative measure-ment of the intercomissural distance?

Output: >70 mm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the diameter on direct intraoperative measure-ment of the intercomissural distance?. ### Response: >70 mm.


Instruction: What is degree of RV dysfunction or remodeling, leaflet tether -ing height, pulmonary artery hypertension, and intra-annular RV pacemaker?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is degree of RV dysfunction or remodeling, leaflet tether -ing height, pulmonary artery hypertension, and intra-annular RV pacemaker?. ### Response: 3.


Instruction: What is the stage B of TR with tricuspid annulus dilation?

Output: progres-sive TR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the stage B of TR with tricuspid annulus dilation?. ### Response: progres-sive TR.


Instruction: What is lacking in the study?

Output: data on outcomes such as survival and major adverse events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lacking in the study?. ### Response: data on outcomes such as survival and major adverse events.


Instruction: Where was the study downloaded from?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where was the study downloaded from?. ### Response: http://ahajournals.


Instruction: When was the paper downloaded from http://ahajournals.org?

Output: April 27, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the paper downloaded from http://ahajournals.org?. ### Response: April 27, 2023.


Instruction: What is one of the side effects of statin?

Output: 67:2395–410

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the side effects of statin?. ### Response: 67:2395–410.


Instruction: What is the name of the journal that reports statin-associated side effects?

Output: ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that reports statin-associated side effects?. ### Response: ahajournals.org.


Instruction: When was this article published?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 28, 2023.


Instruction: What year was the trial of head positioning in acute stroke?

Output: 2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the trial of head positioning in acute stroke?. ### Response: 2019.


Instruction: What is the name of the study?

Output: Acute Candesartan Cilexetil Therapy in Stroke Survivors Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study?. ### Response: Acute Candesartan Cilexetil Therapy in Stroke Survivors Study Group.


Instruction: How is head positioning measured?

Output: flat out wrong

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is head positioning measured?. ### Response: flat out wrong.


Instruction: What is the difference between rightly positioned and flat out wrong?

Output: rightly positioned

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between rightly positioned and flat out wrong?. ### Response: rightly positioned.


Instruction: What does flat-head positioning increase in anterior circulation?

Output: cerebral blood flow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does flat-head positioning increase in anterior circulation?. ### Response: cerebral blood flow.


Instruction: What is a cluster randomized phase IIb trial of?

Output: Flat-head positioning increases cerebral blood flow in anterior circulation acute ischemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cluster randomized phase IIb trial of?. ### Response: Flat-head positioning increases cerebral blood flow in anterior circulation acute ischemic stroke.


Instruction: What is the effect of acute blood pressure variability on ischemic stroke outcome?

Output: increases cerebral blood flow

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of acute blood pressure variability on ischemic stroke outcome?. ### Response: increases cerebral blood flow.


Instruction: What is-chemic stroke outcome?

Output: pressure reduction on death and major disability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is-chemic stroke outcome?. ### Response: pressure reduction on death and major disability.


Instruction: What is the name of the randomized, double-blind, placebo-controlled trial of VENUS?

Output: Very Early Nimodipine Use in Stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, double-blind, placebo-controlled trial of VENUS?. ### Response: Very Early Nimodipine Use in Stroke.


Instruction: Stroke. 2001;32:461–465. doi: 10.1161/01.str.32.2.461 245.

Output: Flat-head positioning

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Stroke. 2001;32:461–465. doi: 10.1161/01.str.32.2.461 245.. ### Response: Flat-head positioning.


Instruction: What is the name of the study that evaluated Acute Candesartan Cilexetil Therapy in Stroke Survivors?

Output: The ACCESS Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated Acute Candesartan Cilexetil Therapy in Stroke Survivors?. ### Response: The ACCESS Study.


Instruction: What study did the ACCESS study evaluate?

Output: Acute Candesartan Cilexetil Therapy in Stroke Survivors Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study did the ACCESS study evaluate?. ### Response: Acute Candesartan Cilexetil Therapy in Stroke Survivors Study Group.


Instruction: What is CHHIPS?

Output: Controlling Hypertension and Hypotension Immediately Post-Stroke (CHHIPS): a randomised, placebo-controlled, double-blind pilot trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CHHIPS?. ### Response: Controlling Hypertension and Hypotension Immediately Post-Stroke (CHHIPS): a randomised, placebo-controlled, double-blind pilot trial.


Instruction: What is the name of the randomised, placebo-controlled, double-blind pilot trial?

Output: Controlling Hypertension and Hypotension Immediately Post-Stroke (CHHIPS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised, placebo-controlled, double-blind pilot trial?. ### Response: Controlling Hypertension and Hypotension Immediately Post-Stroke (CHHIPS.


Instruction: When was the Lancet Neurol 8:48-56?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet Neurol 8:48-56?. ### Response: 2009.


Instruction: What is COSSACS?

Output: a prospective, randomised, open, blinded-endpoint trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is COSSACS?. ### Response: a prospective, randomised, open, blinded-endpoint trial.


Instruction: What is the name of the prospective, randomised, open, blinded-endpoint trial?

Output: COSSACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective, randomised, open, blinded-endpoint trial?. ### Response: COSSACS.


Instruction: When did the Lancet Neurol. 2010;9:767-775?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet Neurol. 2010;9:767-775?. ### Response: 2009.


Instruction: What is the name of the open, blinded-endpoint trial?

Output: Continue or Stop Post-Stroke Antihypertensives Collaborative Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the open, blinded-endpoint trial?. ### Response: Continue or Stop Post-Stroke Antihypertensives Collaborative Study.


Instruction: When did the Lancet Neurol release the results?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet Neurol release the results?. ### Response: 2009.


Instruction: What did the results of the CATIS Investigators show?

Output: Effects of immediate blood pressure reduction on death and major disability in patients with acute ischemic stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the results of the CATIS Investigators show?. ### Response: Effects of immediate blood pressure reduction on death and major disability in patients with acute ischemic stroke.


Instruction: What is the name of the randomized clinical trial that evaluated death and major disability in patients with acute ischemic stroke?

Output: CATIS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized clinical trial that evaluated death and major disability in patients with acute ischemic stroke?. ### Response: CATIS.


Instruction: When was the JAMA 311:479–489?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA 311:479–489?. ### Response: 2014.


Instruction: What was the Efficacy of nitric oxide?

Output: with or without continuing antihy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Efficacy of nitric oxide?. ### Response: with or without continuing antihy.


Instruction: Beridze M, Caso V, et al. Efficacy of nitric oxide, with or without continuing antihypertensive treat-ment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial?

Output: Lancet

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Beridze M, Caso V, et al. Efficacy of nitric oxide, with or without continuing antihypertensive treat-ment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial?. ### Response: Lancet.


Instruction: What is the role of home blood pressure monitoring in overcoming therapeutic inertia and improving hypertension control?

Output: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of home blood pressure monitoring in overcoming therapeutic inertia and improving hypertension control?. ### Response: a systematic review and meta-analysis.


Instruction: When did Hypertension. 201157:29–38?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Hypertension. 201157:29–38?. ### Response: 2011.


Instruction: What is a rationale for fixed-dose combinations in the treatment of hypertension?

Output: the cycle repeats

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a rationale for fixed-dose combinations in the treatment of hypertension?. ### Response: the cycle repeats.


Instruction: What is the rationale for fixed-dose combinations in the treatment of hypertension: the cycle repeats?

Output: Sica DA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the rationale for fixed-dose combinations in the treatment of hypertension: the cycle repeats?. ### Response: Sica DA.


Instruction: 2002;62:443–462. What is a statement for healthcare professionals from the Council on the Kidney in Cardiovascular Disease?

Output: Renal con-siderations in angiotensin converting enzyme inhibitor therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 2002;62:443–462. What is a statement for healthcare professionals from the Council on the Kidney in Cardiovascular Disease?. ### Response: Renal con-siderations in angiotensin converting enzyme inhibitor therapy.


Instruction: What are the Council on the Kidney in Cardiovascular Disease and the Council for High Blood Pressure Research of the American Heart Association?

Output: Renal con-siderations in angiotensin converting enzyme inhibitor therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Council on the Kidney in Cardiovascular Disease and the Council for High Blood Pressure Research of the American Heart Association?. ### Response: Renal con-siderations in angiotensin converting enzyme inhibitor therapy.


Instruction: When was Circulation. 2001;104:1985-1991?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation. 2001;104:1985-1991?. ### Response: 2001.


Instruction: What is the effect of quinapril after coronary artery disease?

Output: reduced ejection fraction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of quinapril after coronary artery disease?. ### Response: reduced ejection fraction.


Instruction: What is the QUO V ADIS Study?

Output: coronary artery bypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the QUO V ADIS Study?. ### Response: coronary artery bypass grafting.


Instruction: What is QUinapril on Vascular Ace and Determinants of Ischemia?

Output: coronary artery bypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is QUinapril on Vascular Ace and Determinants of Ischemia?. ### Response: coronary artery bypass grafting.


Instruction: What does IMAGINE stand for?

Output: Ischemia Management with Accupril post-bypass Graft via Inhibition of the coNverting Enzyme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does IMAGINE stand for?. ### Response: Ischemia Management with Accupril post-bypass Graft via Inhibition of the coNverting Enzyme.


Instruction: What is the name of the group that investigates Ischemia Management with Accupril post-bypass Graft via Inhibition of the coNverting Enzyme?

Output: IMAGINE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that investigates Ischemia Management with Accupril post-bypass Graft via Inhibition of the coNverting Enzyme?. ### Response: IMAGINE.


Instruction: What is artery bypass surgery?

Output: coronary artery bypass grafting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is artery bypass surgery?. ### Response: coronary artery bypass grafting.


Instruction: What is the doi: 10.1161/CIRCULATIONAHA.106.685073?

Output: Circulation. 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1161/CIRCULATIONAHA.106.685073?. ### Response: Circulation. 2008.


Instruction: Sica DA. What is diuretic use in renal disease?

Output: angiotensin converting enzyme inhibitor therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Sica DA. What is diuretic use in renal disease?. ### Response: angiotensin converting enzyme inhibitor therapy.


Instruction: What is a mineralocorticoid receptor antagonist for heart failure with reduced ejection fraction?

Output: integrating evidence into clinical practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a mineralocorticoid receptor antagonist for heart failure with reduced ejection fraction?. ### Response: integrating evidence into clinical practice.


Instruction: What is the name of the study that combines evidence into clinical practice?

Output: QUO V ADIS Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that combines evidence into clinical practice?. ### Response: QUO V ADIS Study.


Instruction: What is the name of the journal that studies ejection fraction?

Output: eurheartj

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies ejection fraction?. ### Response: eurheartj.


Instruction: When did Eur Heart J.33:2782–2795 appear?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J.33:2782–2795 appear?. ### Response: 2012.


Instruction: What was the title of the paper that examined Ejection fraction in 2012?

Output: Eur Heart J. 2012;33:2782–2795. doi: 10.1093/eurheartj/ehs257

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the paper that examined Ejection fraction in 2012?. ### Response: Eur Heart J. 2012;33:2782–2795. doi: 10.1093/eurheartj/ehs257.


Instruction: What is the 2013 ACCF/AHA guideline for the management of heart failure?

Output: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 ACCF/AHA guideline for the management of heart failure?. ### Response: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.


Instruction: What is a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

Output: 2013 ACCF/AHA guideline for the management of heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: 2013 ACCF/AHA guideline for the management of heart failure.


Instruction: What is the acronym for Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

Output: American College

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: American College.


Instruction: When was Circulation 128:e240–e327. doi: 10.1161/CIR.0b013e31829e8776?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Circulation 128:e240–e327. doi: 10.1161/CIR.0b013e31829e8776?. ### Response: 2013.


Instruction: What is another name for metoprolol CR/XL?

Output: Metoprolol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for metoprolol CR/XL?. ### Response: Metoprolol.


Instruction: What is the effect of metoprolol CR/XL in chronic heart failure?

Output: Metoprolol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of metoprolol CR/XL in chronic heart failure?. ### Response: Metoprolol.


Instruction: What may not be feasible or appropriate in people in the later stages of heart failure?

Output: invasive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not be feasible or appropriate in people in the later stages of heart failure?. ### Response: invasive.


Instruction: Why did the committee decide to make a research recommendation to establish the added value of IV or subcutaneous diuretics?

Output: invasive, may not be feasible or appropriate in people in the later stages of heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why did the committee decide to make a research recommendation to establish the added value of IV or subcutaneous diuretics?. ### Response: invasive, may not be feasible or appropriate in people in the later stages of heart failure.


Instruction: How long was the BHF funded pilot study?

Output: 2  year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the BHF funded pilot study?. ### Response: 2  year.


Instruction: How many NHS organisations across the UK participated in the 2 year project?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many NHS organisations across the UK participated in the 2 year project?. ### Response: 10.


Instruction: How long did the project last?

Output: 2  year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the project last?. ### Response: 2  year.


Instruction: How many NHS organisations were involved in the project?

Output: 10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many NHS organisations were involved in the project?. ### Response: 10.


Instruction: ANGIOTENSIN -RECEPTOR BLOCKERSCLASS I1.ARBs are recommended in patients with HF rEF withcurrent or prior symptoms who are ACE inhibitor intolerant to reduce what?

Output: morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: ANGIOTENSIN -RECEPTOR BLOCKERSCLASS I1.ARBs are recommended in patients with HF rEF withcurrent or prior symptoms who are ACE inhibitor intolerant to reduce what?. ### Response: morbidity and mortality.


Instruction: What is a first-line therapy for patients withHFrEF?

Output: ARBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a first-line therapy for patients withHFrEF?. ### Response: ARBs.


Instruction: When were ARBs unless contraindicated?

Output: 190– 195

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were ARBs unless contraindicated?. ### Response: 190– 195.


Instruction: What may be considered in persistentlysymptomatic patients with HF rEF who are already being treated with an ACE inhibitor?

Output: Addition of an ARB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered in persistentlysymptomatic patients with HF rEF who are already being treated with an ACE inhibitor?. ### Response: Addition of an ARB.


Instruction: What is not indicated or tolerated?

Output: an aldosterone antagonist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not indicated or tolerated?. ### Response: an aldosterone antagonist.


Instruction: What is potentially harmful for patients withHFrEF?

Output: Routine combined use of an ACE inhibitor, ARB, and aldo-sterone antagonist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is potentially harmful for patients withHFrEF?. ### Response: Routine combined use of an ACE inhibitor, ARB, and aldo-sterone antagonist.


Instruction: What is the level of evidence for patients withHFrEF?

Output: A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for patients withHFrEF?. ### Response: A.


Instruction: What is recommended for all patients with current or priorsymptoms of HFr EF, unless contraindicated?

Output: Use of 1 of the 3 beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for all patients with current or priorsymptoms of HFr EF, unless contraindicated?. ### Response: Use of 1 of the 3 beta blockers.


Instruction: How many beta blockers have been proven to reduce mortality?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many beta blockers have been proven to reduce mortality?. ### Response: 3.


Instruction: What is contraindicated to reduce morbidity and mortality?

Output: ARBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is contraindicated to reduce morbidity and mortality?. ### Response: ARBs.


Instruction: What is the level of evidence for aldosterone receptor antagonists?

Output: B

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence for aldosterone receptor antagonists?. ### Response: B.


Instruction: What percentage of LVEF is required to reduce morbidity and mortality?

Output: 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of LVEF is required to reduce morbidity and mortality?. ### Response: 35%.


Instruction: Patients with NYHA class II HF should have a history of what?

Output: prior cardiovascular hospitalization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with NYHA class II HF should have a history of what?. ### Response: prior cardiovascular hospitalization.


Instruction: What should be 2.5 mg/dL or less in men?

Output: Creatinines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be 2.5 mg/dL or less in men?. ### Response: Creatinines.


Instruction: What should be less than5.0 mEq/L?

Output: potassium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be less than5.0 mEq/L?. ### Response: potassium.


Instruction: What is the risk of hyperkalemia and renal ficiency?

Output: life-threatening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of hyperkalemia and renal ficiency?. ### Response: life-threatening.


Instruction: To minimize risk of hyperkalemia and renal insuf ficiency (181,182,197)?

Output: Careful monitoring of potassium, renalfunction, and diuretic dosing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To minimize risk of hyperkalemia and renal insuf ficiency (181,182,197)?. ### Response: Careful monitoring of potassium, renalfunction, and diuretic dosing.


Instruction: What is recommended to reduce morbidity and mortality following an acute MI?

Output: Aldosterone receptor antagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended to reduce morbidity and mortality following an acute MI?. ### Response: Aldosterone receptor antagonists.


Instruction: What is the name of the class of aldosterone receptor antagonists?

Output: CLASS I1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the class of aldosterone receptor antagonists?. ### Response: CLASS I1.


Instruction: What is a life-threatening hyperkalemia or renal insuf ficiency?

Output: serum creatinine is greater than

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a life-threatening hyperkalemia or renal insuf ficiency?. ### Response: serum creatinine is greater than.


Instruction: What type of patients had creatinine >30 mL/min and K+ 5.0 mEq/dL?

Output: NYHA class II-IV

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of patients had creatinine >30 mL/min and K+ 5.0 mEq/dL?. ### Response: NYHA class II-IV.


Instruction: For persistent symptomaticAfrican Americans,NYHA class III-IVClass I, LOE AACEI or ARB ANDBeta BlockerClass I or LOE CLoop DiureticsClass I?

Output: LOE A

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For persistent symptomaticAfrican Americans,NYHA class III-IVClass I, LOE AACEI or ARB ANDBeta BlockerClass I or LOE CLoop DiureticsClass I?. ### Response: LOE A.


Instruction: Why was this trial terminated early?

Output: slow enrollment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was this trial terminated early?. ### Response: slow enrollment.


Instruction: Why was FASTER underpowered?

Output: early termination

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was FASTER underpowered?. ### Response: early termination.


Instruction: What were the statin doses used in FASTER?

Output: moderate intensity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the statin doses used in FASTER?. ### Response: moderate intensity.


Instruction: What was FASTER not recommended for?

Output: secondary stroke prevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was FASTER not recommended for?. ### Response: secondary stroke prevention.


Instruction: What was ASSORT?

Output: Administration of Statin on Acute Ischemic Stroke Patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was ASSORT?. ### Response: Administration of Statin on Acute Ischemic Stroke Patient.


Instruction: When were statins started within 24 hours or on the seventh day?

Output: ASSORT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When were statins started within 24 hours or on the seventh day?. ### Response: ASSORT.


Instruction: What should women of childbearing age who are treated with statin therapy be counseled to use?

Output: a reliable form of contraception

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should women of childbearing age who are treated with statin therapy be counseled to use?. ### Response: a reliable form of contraception.


Instruction: What is a reliable form of contraception?

Output: statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reliable form of contraception?. ### Response: statin therapy.


Instruction: What should women of childbearing age with hypercholesterolemia stop 1 to 2 months before pregnancy is attempted?

Output: the statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should women of childbearing age with hypercholesterolemia stop 1 to 2 months before pregnancy is attempted?. ### Response: the statin.


Instruction: What should be stopped as soon as the pregnancy is discovered?

Output: statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be stopped as soon as the pregnancy is discovered?. ### Response: statin.


Instruction: What is unchanged from 2018 Cholesterol Guidelines?

Output: C-LDRecommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is unchanged from 2018 Cholesterol Guidelines?. ### Response: C-LDRecommendation.


Instruction: In adults with advanced kidney disease that requires dialysis treatment, it may be reasonable to continue what?

Output: the statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adults with advanced kidney disease that requires dialysis treatment, it may be reasonable to continue what?. ### Response: the statin.


Instruction: What may be reasonable to continue the statin?

Output: adults with advanced kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be reasonable to continue the statin?. ### Response: adults with advanced kidney disease.


Instruction: What is not recommended in adults with advanced kidney disease who require dialysis treatment?

Output: initiation of a statin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended in adults with advanced kidney disease who require dialysis treatment?. ### Response: initiation of a statin.


Instruction: When was the download from http://ahajournals.org by?

Output: April

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the download from http://ahajournals.org by?. ### Response: April.


Instruction: How many economic evaluations were identified in the 2003 guideline (CG5)?

Output: No

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many economic evaluations were identified in the 2003 guideline (CG5)?. ### Response: No.


Instruction: How many previously published economic evaluation was included in the guideline?

Output: One

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many previously published economic evaluation was included in the guideline?. ### Response: One.


Instruction: What was included in the 2010 guideline update?

Output: One previously published economic evaluation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was included in the 2010 guideline update?. ### Response: One previously published economic evaluation.


Instruction: What was the economic evaluation that assessed NP guided monitoring to usual care based on a clinical trial by Troughton et al. 2000339.

Output: CG108

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the economic evaluation that assessed NP guided monitoring to usual care based on a clinical trial by Troughton et al. 2000339.. ### Response: CG108.


Instruction: What is the US Medicare perspective?

Output: excluded from this review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the US Medicare perspective?. ### Response: excluded from this review.


Instruction: In what year was an original economic analysis conducted for this question?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year was an original economic analysis conducted for this question?. ### Response: 2010.


Instruction: What was included in the update of the economic analysis?

Output: new clinical evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was included in the update of the economic analysis?. ### Response: new clinical evidence.


Instruction: What type of evidence has been included in this review?

Output: health economic evaluations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of evidence has been included in this review?. ### Response: health economic evaluations.


Instruction: How many health economic evaluations were identified with the relevant comparison?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many health economic evaluations were identified with the relevant comparison?. ### Response: two.


Instruction: What is the summarised health economic evidence profile?

Output: health economic evaluations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the summarised health economic evidence profile?. ### Response: health economic evaluations.


Instruction: What is the health economic study selection flow chart in Appendix D?

Output: Appendix  G. See also the health economic study selection flow chart in Appendix  D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the health economic study selection flow chart in Appendix D?. ### Response: Appendix  G. See also the health economic study selection flow chart in Appendix  D.


Instruction: • if there is a potential t o salv age brain tissue, as sho wn by imaging such as CT perfusion or diffusion-w eight ed MRI sequences?

Output: ential

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: • if there is a potential t o salv age brain tissue, as sho wn by imaging such as CT perfusion or diffusion-w eight ed MRI sequences?. ### Response: ential.


Instruction: What is t he factor in r ecommendation 1.4.8?

Output: Take into account t he person's o verall clinical status and t he extent of established inf arction on initial brain imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he factor in r ecommendation 1.4.8?. ### Response: Take into account t he person's o verall clinical status and t he extent of established inf arction on initial brain imaging.


Instruction: What should a woman do to get her wit h intra venous thrombolysis?

Output: as soon as possible

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a woman do to get her wit h intra venous thrombolysis?. ### Response: as soon as possible.


Instruction: How long before people last kno wn to be w ell up?

Output: 24 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long before people last kno wn to be w ell up?. ### Response: 24 hours.


Instruction: Who has acut e ischaemic str oke and confirmed occlusion of pr oximal posterior cir culation?

Output: CT A or MRA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who has acut e ischaemic str oke and confirmed occlusion of pr oximal posterior cir culation?. ### Response: CT A or MRA.


Instruction: What is t he pr oximal posterior cir culation?

Output: basilar or post erior cer ebral ar tery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he pr oximal posterior cir culation?. ### Response: basilar or post erior cer ebral ar tery.


Instruction: What can be demonstrated by CT A or MRA?

Output: occlusion of t he pr oximal posterior cir culation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be demonstrated by CT A or MRA?. ### Response: occlusion of t he pr oximal posterior cir culation.


Instruction: What is sho wing limit ed inf arct cor e volume taking int o account t he factors in r ecommendation 1.4.8?

Output: if there is t he pot ential t o salv age brain tissue

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is sho wing limit ed inf arct cor e volume taking int o account t he factors in r ecommendation 1.4.8?. ### Response: if there is t he pot ential t o salv age brain tissue.


Instruction: What should a person's o verall clinical status and extent of established inf arction on initial brain imaging inform?

Output: decisions about thrombect omy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a person's o verall clinical status and extent of established inf arction on initial brain imaging inform?. ### Response: decisions about thrombect omy.


Instruction: What should people who have (in addition to the factors in recommendations 1.4.5 to 1.4.7) take into account?

Output: person's o verall clinical status

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should people who have (in addition to the factors in recommendations 1.4.5 to 1.4.7) take into account?. ### Response: person's o verall clinical status.


Instruction: What is the pre-str oke functional status of less than 3 on t he modified Rankin scale?

Output: • a pre-str oke functional status of less t han 3 on t he modified Rankin scale and • a scor e of mor e than 5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the pre-str oke functional status of less than 3 on t he modified Rankin scale?. ### Response: • a pre-str oke functional status of less t han 3 on t he modified Rankin scale and • a scor e of mor e than 5.


Instruction: What is a scor e of more than 5 on the National Institutes of Healt h Stroke Scale (NIHSS)?

Output: a pre-str oke functional status of less t han 3 on t he modified Rankin scale and •

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a scor e of more than 5 on the National Institutes of Healt h Stroke Scale (NIHSS)?. ### Response: a pre-str oke functional status of less t han 3 on t he modified Rankin scale and •.


Instruction: What is the National Institut es of Healt h Str oke Scale?

Output: NIHSS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the National Institut es of Healt h Str oke Scale?. ### Response: NIHSS.


Instruction: What is a shor t explanation of wh y the committee made?

Output: 2019 r ecommendations and how they might aff ect practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a shor t explanation of wh y the committee made?. ### Response: 2019 r ecommendations and how they might aff ect practice.


Instruction: What is the impact section on thrombect omy for people wit h acut e ischaemic str oke?

Output: 1.4.8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact section on thrombect omy for people wit h acut e ischaemic str oke?. ### Response: 1.4.8.


Instruction: Full details of the evidence and t he committ ee's discussion ar e in evidence r eview D: what?

Output: thrombect omy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Full details of the evidence and t he committ ee's discussion ar e in evidence r eview D: what?. ### Response: thrombect omy.


Instruction: What is the name of the book that diagnoses and initial management?

Output: NG128

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that diagnoses and initial management?. ### Response: NG128.


Instruction: When was the last updat ed on 13 April 2022?

Output: 12of 48

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed on 13 April 2022?. ### Response: 12of 48.


Instruction: What is the most common reason for later surgical reintervention?

Output: gitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common reason for later surgical reintervention?. ### Response: gitation.


Instruction: When are there few long-term follow-up studies of patients after AVSD repair?

Output: childhood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When are there few long-term follow-up studies of patients after AVSD repair?. ### Response: childhood.


Instruction: The atrioventricular node is typically displaced infe-riorly in what?

Output: AVSD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The atrioventricular node is typically displaced infe-riorly in what?. ### Response: AVSD.


Instruction: What is typically displaced infe-riorly in AVSD?

Output: The atrioventricular node

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is typically displaced infe-riorly in AVSD?. ### Response: The atrioventricular node.


Instruction: What is associated with relative hypopla-sia of the left anterior fascicle?

Output: The atrioventricular node

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with relative hypopla-sia of the left anterior fascicle?. ### Response: The atrioventricular node.


Instruction: How long after surgery has late-onset com-plete heart block been noted?

Output: 15 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after surgery has late-onset com-plete heart block been noted?. ### Response: 15 years.


Instruction: What is important to evaluate for conduction abnormalities?

Output: Regular monitoring for symptoms and screening with an ECG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important to evaluate for conduction abnormalities?. ### Response: Regular monitoring for symptoms and screening with an ECG.


Instruction: Who should perform surgeries, cardiac catheterization and other procedures?

Output: S4.1.4-10See Section 3.3 for recommendations on who should perform surgeries, cardiac catheterization, and other procedures in these patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should perform surgeries, cardiac catheterization and other procedures?. ### Response: S4.1.4-10See Section 3.3 for recommendations on who should perform surgeries, cardiac catheterization, and other procedures in these patients.


Instruction: Who should perform surgeries, cardiac catheterization, and other procedures in patients with AVSD?

Output: Section 3.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should perform surgeries, cardiac catheterization, and other procedures in patients with AVSD?. ### Response: Section 3.3.


Instruction: What section for recommendations on diagnostic evaluation is included in Section 3.4?

Output: Sec-tion 4.1.1 for recommendations on primum ASD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What section for recommendations on diagnostic evaluation is included in Section 3.4?. ### Response: Sec-tion 4.1.1 for recommendations on primum ASD.


Instruction: Where are recommendations on primum ASD located?

Output: Sec-tion 4.1.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are recommendations on primum ASD located?. ### Response: Sec-tion 4.1.1.


Instruction: How is Eisenmenger syndrome evaluated and managed?

Output: Section 4.4.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is Eisenmenger syndrome evaluated and managed?. ### Response: Section 4.4.6.


Instruction: Invasive hemodynamic assessment still has an im-portant role as what?

Output: a confirmatory tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Invasive hemodynamic assessment still has an im-portant role as what?. ### Response: a confirmatory tool.


Instruction: What does carry prognostic significance for adults with shunts?

Output: pulmonary vasoreactivity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does carry prognostic significance for adults with shunts?. ### Response: pulmonary vasoreactivity.


Instruction: The left atrioventricular valve in an AVSD is what type of valve?

Output: mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The left atrioventricular valve in an AVSD is what type of valve?. ### Response: mitral valve.


Instruction: What is not anatomically the same as a mitral valve in an AVSD malformation?

Output: left atrioventricular valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not anatomically the same as a mitral valve in an AVSD malformation?. ### Response: left atrioventricular valve.


Instruction: What can be extrapolated from the VHD guideline for mitral regurgitation and mitral stenosis?

Output: the criteria for consideration of left atrioventric-ular valve surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be extrapolated from the VHD guideline for mitral regurgitation and mitral stenosis?. ### Response: the criteria for consideration of left atrioventric-ular valve surgery.


Instruction: What is the morphology of the LVOT?

Output: anterior, narrow, and potentially obstructed structure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the morphology of the LVOT?. ### Response: anterior, narrow, and potentially obstructed structure.


Instruction: What is an anterior, narrow, and potentially obstructed structure?

Output: the LVOT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an anterior, narrow, and potentially obstructed structure?. ### Response: the LVOT.


Instruction: What is needed to repair LVOT?

Output: congenital surgical exper -tise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to repair LVOT?. ### Response: congenital surgical exper -tise.


Instruction: Patients with AVSD typically have at least how many previous attempts to repair it?

Output: 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with AVSD typically have at least how many previous attempts to repair it?. ### Response: 1.


Instruction: Some patients may have what other anatomic lesions?

Output: sub-aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Some patients may have what other anatomic lesions?. ### Response: sub-aortic stenosis.


Instruction: What is another term for sub-aortic stenosis?

Output: subAS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for sub-aortic stenosis?. ### Response: subAS.


Instruction: In 1 meta-analysis of studies of adult left atrioventricular valve surgery in patients with AVSD, the risk of needing a pacemaker was higher in patients who underwent valve replacement than in those who un-derwent repair?

Output: aortic stenosis [subAS]). In 1 meta-analysis of studies of adult left atrioventricular valve sur -gery in patients with AVSD, the risk of needing a pacemaker was higher in those who under -went valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In 1 meta-analysis of studies of adult left atrioventricular valve surgery in patients with AVSD, the risk of needing a pacemaker was higher in patients who underwent valve replacement than in those who un-derwent repair?. ### Response: aortic stenosis [subAS]). In 1 meta-analysis of studies of adult left atrioventricular valve sur -gery in patients with AVSD, the risk of needing a pacemaker was higher in those who under -went valve replacement.


Instruction: What percentage of repaired patients required Atrioventricular Septal Defect RecommendationsDownloaded from http://ahajournals.org by on April 28, 2023?

Output: one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of repaired patients required Atrioventricular Septal Defect RecommendationsDownloaded from http://ahajournals.org by on April 28, 2023?. ### Response: one third.


Instruction: What is the focus of the Focused Update on Atrial FibrillationCirculation. 2019;140:e125–e151?

Output: Publication of potentially prac-tice-changing new study results relevant to an existing or new drug, device, or management strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of the Focused Update on Atrial FibrillationCirculation. 2019;140:e125–e151?. ### Response: Publication of potentially prac-tice-changing new study results relevant to an existing or new drug, device, or management strategy.


Instruction: What is one of the changes to the structure of guidelines?

Output: word limits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the changes to the structure of guidelines?. ### Response: word limits.


Instruction: How is the Preamble presented?

Output: in ab-breviated form in the executive summary and full-text guideline documents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the Preamble presented?. ### Response: in ab-breviated form in the executive summary and full-text guideline documents.


Instruction: In addition to word limits and a web guideline supplement, what other changes are there?

Output: structured guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In addition to word limits and a web guideline supplement, what other changes are there?. ### Response: structured guidelines.


Instruction: Why is the Preamble presented in abbreviated form in executive summary and full-text guideline documents?

Output: to promote conciseness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the Preamble presented in abbreviated form in executive summary and full-text guideline documents?. ### Response: to promote conciseness.


Instruction: When appropriate and feasible, an analysis of value for a drug, device, or in-tervention may be performed in accordance with what?

Output: ACC/AHA methodology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When appropriate and feasible, an analysis of value for a drug, device, or in-tervention may be performed in accordance with what?. ### Response: ACC/AHA methodology.


Instruction: What may be performed in accordance with the ACC/AHA methodology?

Output: an analysis of value for a drug, device, or in-tervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be performed in accordance with the ACC/AHA methodology?. ### Response: an analysis of value for a drug, device, or in-tervention.


Instruction: How often are full guideline revisions commissioned?

Output: 6-year cycles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often are full guideline revisions commissioned?. ### Response: 6-year cycles.


Instruction: Who evaluates study results relevant to an existing or new drug, device, or management strategy?

Output: the Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who evaluates study results relevant to an existing or new drug, device, or management strategy?. ### Response: the Task Force.


Instruction: Who consults with the relevant guideline writing committee to determine whether a focused update should be commissioned?

Output: the Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who consults with the relevant guideline writing committee to determine whether a focused update should be commissioned?. ### Response: the Task Force.


Instruction: For additional information and policies on guideline de-velopment, please consult what?

Output: ACC/AHA guideline methodology manual

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For additional information and policies on guideline de-velopment, please consult what?. ### Response: ACC/AHA guideline methodology manual.


Instruction: What does the Task Force strive to ensure the guideline writing committee contains?

Output: requisite expertise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Task Force strive to ensure the guideline writing committee contains?. ### Response: requisite expertise.


Instruction: What is the ACC/AHA guideline methodology manual?

Output: P-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA guideline methodology manual?. ### Response: P-4.


Instruction: What are some of the back-grounds of the medical commu-nity selected from?

Output: different geographic regions, sexes, races, ethnicities, intellectual perspectives/bi-ases, and scopes of clinical practice

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the back-grounds of the medical commu-nity selected from?. ### Response: different geographic regions, sexes, races, ethnicities, intellectual perspectives/bi-ases, and scopes of clinical practice.