Instruction: Inducibility appears to reverse correlate with what?

Output: LVEF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inducibility appears to reverse correlate with what?. ### Response: LVEF.


Instruction: What is a common manifestation of cardiac sarcoidosis?

Output: conduction abnormalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common manifestation of cardiac sarcoidosis?. ### Response: conduction abnormalities.


Instruction: What are patients with documented VA and LV dysfunction at increased risk of?

Output: cardiac events including cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with documented VA and LV dysfunction at increased risk of?. ### Response: cardiac events including cardiac death.


Instruction: What are patients with VA and LV dysfunction at increased risk of?

Output: cardiac events including cardiac death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with VA and LV dysfunction at increased risk of?. ### Response: cardiac events including cardiac death.


Instruction: How many patients had high-degree atrioventricular block as the initial manifestation of cardiac sar -coidosis?

Output: 22

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had high-degree atrioventricular block as the initial manifestation of cardiac sar -coidosis?. ### Response: 22.


Instruction: What was the median follow-up of patients with VT and/or HF?

Output: 34 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median follow-up of patients with VT and/or HF?. ### Response: 34 months.


Instruction: What was the median follow up of patients with heart block?

Output: 34 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median follow up of patients with heart block?. ### Response: 34 months.


Instruction: What was similar to those with VT and/or HF?

Output: fatal car -diac events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was similar to those with VT and/or HF?. ### Response: fatal car -diac events.


Instruction: What suggests that the risk of fatal cardiac events is high regardless of the initial clinical presentation?

Output: fatal car -diac events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What suggests that the risk of fatal cardiac events is high regardless of the initial clinical presentation?. ### Response: fatal car -diac events.


Instruction: What did administration of steroids lead to in the same study?

Output: clini-cal improvement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did administration of steroids lead to in the same study?. ### Response: clini-cal improvement.


Instruction: What did not seem to be protective against adverse cardiac events?

Output: steroid effectiveness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did not seem to be protective against adverse cardiac events?. ### Response: steroid effectiveness.


Instruction: What has been attempted to evaluate the role of immunosuppression for reducing VA?

Output: Several studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been attempted to evaluate the role of immunosuppression for reducing VA?. ### Response: Several studies.


Instruction: What was not superior to drug therapy for the primary cardiovascular outcomes of death, disabling stroke, serious bleeding, or cardiac arrest at 5 years among patients with new-onset or un-treated AF that required therapy?

Output: AF ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not superior to drug therapy for the primary cardiovascular outcomes of death, disabling stroke, serious bleeding, or cardiac arrest at 5 years among patients with new-onset or un-treated AF that required therapy?. ### Response: AF ablation.


Instruction: What does Online Data Supplement 8.COR LOE RecommendationsI B-R1 do?

Output: Referenced studies that support new or modified recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Online Data Supplement 8.COR LOE RecommendationsI B-R1 do?. ### Response: Referenced studies that support new or modified recommendations.


Instruction: What is the risk score for systemic thromboembolism used for?

Output: 2 or greater

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk score for systemic thromboembolism used for?. ### Response: 2 or greater.


Instruction: What is recommended unless the bleeding risk exceeds the expected benefit?

Output: anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended unless the bleeding risk exceeds the expected benefit?. ### Response: anticoagulation.


Instruction: What was updated from C in the 2014 AF Guideline to B-R?

Output: LOE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was updated from C in the 2014 AF Guideline to B-R?. ### Response: LOE.


Instruction: What is recommended for patients with hemodynamic compromise, ongoing ischemia, or inadequate rate control?

Output: Urgent direct-current cardioversion of new-onset AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for patients with hemodynamic compromise, ongoing ischemia, or inadequate rate control?. ### Response: Urgent direct-current cardioversion of new-onset AF.


Instruction: What are intravenous beta blockers recommended to slow?

Output: a rapid ventricular response to AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are intravenous beta blockers recommended to slow?. ### Response: a rapid ventricular response to AF.


Instruction: What type of therapy is recommended to slow a rapid ventricular response to AF in patients with ACS who do not display HF, hemodynamic instability, or bronchospasm?

Output: Intravenous beta blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of therapy is recommended to slow a rapid ventricular response to AF in patients with ACS who do not display HF, hemodynamic instability, or bronchospasm?. ### Response: Intravenous beta blockers.


Instruction: What is recommended if triple therapy is prescribed for patients with acute AF at increased risk of stroke?

Output: double therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended if triple therapy is prescribed for patients with acute AF at increased risk of stroke?. ### Response: double therapy.


Instruction: What is PCI with stenting for ACS called?

Output: percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PCI with stenting for ACS called?. ### Response: percutaneous coronary intervention.


Instruction: What is clopidogrel in preference to?

Output: prasugrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel in preference to?. ### Response: prasugrel.


Instruction: Which drug is more likely to cause stroke in patients with AF?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drug is more likely to cause stroke in patients with AF?. ### Response: triple therapy.


Instruction: What is B-R5 in patients with AF at increased risk of stroke based on CHA2DS2-VASc risk score of 2 or greater?

Output: triple therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is B-R5 in patients with AF at increased risk of stroke based on CHA2DS2-VASc risk score of 2 or greater?. ### Response: triple therapy.


Instruction: What is clopidogrel or ticagrelor?

Output: P2Y12 inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is clopidogrel or ticagrelor?. ### Response: P2Y12 inhibitors.


Instruction: What is reasonable to reduce the risk of bleeding as compared with triple therapy?

Output: double therapy with P2Y12 inhibitors (clopidogrel) and low-dose rivaroxaban 15 mg daily

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to reduce the risk of bleeding as compared with triple therapy?. ### Response: double therapy with P2Y12 inhibitors (clopidogrel) and low-dose rivaroxaban 15 mg daily.


Instruction: New RCT data and data from 2 registries and a retrospective cohort study are available.

Output: S7.4-3,S7.4-6–S7.4-8

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: New RCT data and data from 2 registries and a retrospective cohort study are available.. ### Response: S7.4-3,S7.4-6–S7.4-8.


Instruction: What is low-dose rivaroxaban 15 mg daily?

Output: reasonable to reduce the risk of bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low-dose rivaroxaban 15 mg daily?. ### Response: reasonable to reduce the risk of bleeding.


Instruction: What is the CHA2DS2-VASc risk score?

Output: 2 or greater

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CHA2DS2-VASc risk score?. ### Response: 2 or greater.


Instruction: When will the new published data be available?

Output: April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When will the new published data be available?. ### Response: April 23, 2023.


Instruction: What is the name of the new publication?

Output: IIa B-R5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the new publication?. ### Response: IIa B-R5.


Instruction: What is associated with lower risk of all-cause mortality in US adults?

Output: Higher diet quality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with lower risk of all-cause mortality in US adults?. ### Response: Higher diet quality.


Instruction: What is higher diet quality asso-ciated with decreased risk of?

Output: all-cause cardiovascular disease and cancer mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is higher diet quality asso-ciated with decreased risk of?. ### Response: all-cause cardiovascular disease and cancer mortality.


Instruction: How many mm Hg per second should you deflate the cuff pressure for auscultatory readings?

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mm Hg per second should you deflate the cuff pressure for auscultatory readings?. ### Response: 2.


Instruction: Record SBP and DBP as onset of the first Korotkoff sound and disappearance of what sound?

Output: all Korotkoff

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Record SBP and DBP as onset of the first Korotkoff sound and disappearance of what sound?. ### Response: all Korotkoff.


Instruction: What is the nearest even number?

Output: SBP and DBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the nearest even number?. ### Response: SBP and DBP.


Instruction: How many readings were obtained on 2 occasions to estimate the level of BP?

Output: ≥ 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many readings were obtained on 2 occasions to estimate the level of BP?. ### Response: ≥ 2.


Instruction: How many occasions were obtained to estimate the individual’s level of BP?

Output: ≥ 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many occasions were obtained to estimate the individual’s level of BP?. ### Response: ≥ 2.


Instruction: Provide patients with the SBP/DBP readings verbally and in writing123456Properly prepare thepatientTake the proper technique for what?

Output: diagnosis andtreatment of elevatedBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Provide patients with the SBP/DBP readings verbally and in writing123456Properly prepare thepatientTake the proper technique for what?. ### Response: diagnosis andtreatment of elevatedBP.


Instruction: What is BP in infants supposed to be taken while supine and the use of the bell is recommended?

Output: Modi ﬁcation for pediatrics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is BP in infants supposed to be taken while supine and the use of the bell is recommended?. ### Response: Modi ﬁcation for pediatrics.


Instruction: What is the name of the journal that published the guidelines for the prevention, detection, evaluation, and management of high blood pressure in adults?

Output: Journal of the American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that published the guidelines for the prevention, detection, evaluation, and management of high blood pressure in adults?. ### Response: Journal of the American College of Cardiology.


Instruction: What is the name of the Task Force on Clinical Practice Guidelines?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Clinical Practice Guidelines?. ### Response: American College of Cardiology/American Heart Association.


Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is the name of the guideline for management of VHD?

Output: Recommendation-Specific Supportive Text

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the guideline for management of VHD?. ### Response: Recommendation-Specific Supportive Text.


Instruction: When did Otto and colleagues publish their guideline?

Output: 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227. DOI: 10.1161/CIR.0000000000000923 February 2, 2021

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Otto and colleagues publish their guideline?. ### Response: 2020 ACC/AHA Guideline for the Management of Valvular Heart DiseaseCirculation. 2021;143:e72–e227. DOI: 10.1161/CIR.0000000000000923 February 2, 2021.


Instruction: What is the risk of noncar -diac intervention?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of noncar -diac intervention?. ### Response: 3.


Instruction: What are the LV and/or RV response to the overload caused by VHD?

Output: the pulmonary artery systolic pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the LV and/or RV response to the overload caused by VHD?. ### Response: the pulmonary artery systolic pressure.


Instruction: If the patient meets standard criteria for a cardiac intervention, it is prudent to proceed to what?

Output: valve intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the patient meets standard criteria for a cardiac intervention, it is prudent to proceed to what?. ### Response: valve intervention.


Instruction: What type of surgery may be necessary in the presence of uncorrected severe valve disease?

Output: noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of surgery may be necessary in the presence of uncorrected severe valve disease?. ### Response: noncardiac surgery.


Instruction: All patients with severe VHD who are undergoing noncardiac surgery benefit from what?

Output: an evaluation by a Heart Team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: All patients with severe VHD who are undergoing noncardiac surgery benefit from what?. ### Response: an evaluation by a Heart Team.


Instruction: What is a Heart Team consisting of?

Output: a cardiologist, cardiac anesthesiologist, and cardiac surgeons

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a Heart Team consisting of?. ### Response: a cardiologist, cardiac anesthesiologist, and cardiac surgeons.


Instruction: What is noninvasive monitoring in con-sultation with a cardiovascular anesthesiologist?

Output: mild to moderate VHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is noninvasive monitoring in con-sultation with a cardiovascular anesthesiologist?. ### Response: mild to moderate VHD.


Instruction: What may be all that is needed for moderate VHD?

Output: noninvasive monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be all that is needed for moderate VHD?. ### Response: noninvasive monitoring.


Instruction: What should be made in patients with severe VHD who are undergoing elevated-risk noncardiac surgery?

Output: decisions should be made as to whether to proceed with the non-cardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be made in patients with severe VHD who are undergoing elevated-risk noncardiac surgery?. ### Response: decisions should be made as to whether to proceed with the non-cardiac surgery.


Instruction: What should be performed intraop-eratively and postoperatively in an intensive care setting?

Output: invasive hemodynamic or TEE imaging monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be performed intraop-eratively and postoperatively in an intensive care setting?. ### Response: invasive hemodynamic or TEE imaging monitoring.


Instruction: What should patients who have known or suspected VHD of moderate or greater degree benefit from?

Output: TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients who have known or suspected VHD of moderate or greater degree benefit from?. ### Response: TTE.


Instruction: What can be used if there has been no change in clinical course within the past 12 months?

Output: an echocardiogram

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used if there has been no change in clinical course within the past 12 months?. ### Response: an echocardiogram.


Instruction: Why have most adverse events occurred?

Output: because the diagnosis of VHD was not known to the surgical team

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why have most adverse events occurred?. ### Response: because the diagnosis of VHD was not known to the surgical team.


Instruction: What was not known to the surgical team?

Output: the diagnosis of VHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not known to the surgical team?. ### Response: the diagnosis of VHD.


Instruction: What should the echocardio-graphic evaluation quantify?

Output: the severity of valve stenosis or regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the echocardio-graphic evaluation quantify?. ### Response: the severity of valve stenosis or regurgitation.


Instruction: What percentage of patients with AS are over 65 years old?

Output: 1% to 2%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with AS are over 65 years old?. ### Response: 1% to 2%.


Instruction: What percent of AS patients are over 75?

Output: 3% to 8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percent of AS patients are over 75?. ### Response: 3% to 8%.


Instruction: When is severe AS associated with an increased risk?

Output: noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When is severe AS associated with an increased risk?. ### Response: noncardiac surgery.


Instruction: What may be poorly tolerated during the altered hemodynamics of anesthesia and noncardiac surgery?

Output: Rheumatic MS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be poorly tolerated during the altered hemodynamics of anesthesia and noncardiac surgery?. ### Response: Rheumatic MS.


Instruction: What are better tolerated but still convey increased risk?

Output: Left-sided regurgitant lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are better tolerated but still convey increased risk?. ### Response: Left-sided regurgitant lesions.


Instruction: What are the anesthesiologist and surgeon unaware of?

Output: the diagnosis or severity of valve disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the anesthesiologist and surgeon unaware of?. ### Response: the diagnosis or severity of valve disease.


Instruction: What did the Multi-Ethnic Study of Atherosclerosis do?

Output: prediction of risk of hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Multi-Ethnic Study of Atherosclerosis do?. ### Response: prediction of risk of hypertension.


Instruction: What is a risk score for predicting near-term incidence of hypertension?

Output: S3.2-3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk score for predicting near-term incidence of hypertension?. ### Response: S3.2-3.


Instruction: What is the name of the multi-ethnic study of atherosclerosis in middle-aged and older adults?

Output: Framingham Heart Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multi-ethnic study of atherosclerosis in middle-aged and older adults?. ### Response: Framingham Heart Study.


Instruction: In what year did Hypertension publish a 57:1101-07?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Hypertension publish a 57:1101-07?. ### Response: 2011.


Instruction: What is the risk for developing hypertension in middle-aged women and men?

Output: Residual lifetime risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk for developing hypertension in middle-aged women and men?. ### Response: Residual lifetime risk.


Instruction: When did the Framingham Heart Study begin?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Framingham Heart Study begin?. ### Response: 2002.


Instruction: What study did the Johns Hopkins Precursors Study focus on?

Output: atherosclerosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study did the Johns Hopkins Precursors Study focus on?. ### Response: atherosclerosis.


Instruction: What did the Johns Hopkins Precursors Study do?

Output: Body mass index and risk of incident hypertension over the life course

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Johns Hopkins Precursors Study do?. ### Response: Body mass index and risk of incident hypertension over the life course.


Instruction: What is the Prevalence of High BP S3.3-1?

Output: Whelton PK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Prevalence of High BP S3.3-1?. ### Response: Whelton PK.


Instruction: Who is the author of The elusiveness of population-wide high blood pressure control?

Output: Whelton PK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of The elusiveness of population-wide high blood pressure control?. ### Response: Whelton PK.


Instruction: What is the seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure?

Output: S3.3-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure?. ### Response: S3.3-4.


Instruction: What are the results of the Circ Cardiovasc Qual Outcomes 2012?

Output: National surveillance defini-tions for hypertension prevalence and control among adults. Circ Cardiovasc Qual Outcomes. 2012;5:343

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the Circ Cardiovasc Qual Outcomes 2012?. ### Response: National surveillance defini-tions for hypertension prevalence and control among adults. Circ Cardiovasc Qual Outcomes. 2012;5:343.


Instruction: What is the fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure?

Output: S3.3-5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure?. ### Response: S3.3-5.


Instruction: Who is the Committee on Detection, Evaluation, and Treatment of High Blood Pressure?

Output: Joint National Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Committee on Detection, Evaluation, and Treatment of High Blood Pressure?. ### Response: Joint National Committee.


Instruction: What is JNC V?

Output: Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is JNC V?. ### Response: Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure.


Instruction: When did the Third National Health and Nutrition Examination Survey take place?

Output: 1988–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Third National Health and Nutrition Examination Survey take place?. ### Response: 1988–.


Instruction: What did the World Hypertension League Expert Committee recommend?

Output: Standards for the uniform reporting of hypertension in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the World Hypertension League Expert Committee recommend?. ### Response: Standards for the uniform reporting of hypertension in adults.


Instruction: When did the Hypertension and Nutrition Examination Survey take place?

Output: 1988–1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Hypertension and Nutrition Examination Survey take place?. ### Response: 1988–1991.


Instruction: What was the name of the 1995 issue of Hypertension?

Output: 26:60–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the 1995 issue of Hypertension?. ### Response: 26:60–.


Instruction: What is the acronym for Awareness, Treatment, and Control?

Output: S3.4-1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Awareness, Treatment, and Control?. ### Response: S3.4-1.


Instruction: When did the Health Examination Surveys take place?

Output: 1960 to 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Health Examination Surveys take place?. ### Response: 1960 to 1991.


Instruction: What was the name of the survey that took place from 1960 to 1991?

Output: Health Examination Surveys

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the survey that took place from 1960 to 1991?. ### Response: Health Examination Surveys.


Instruction: What is the name of the journal that studies the prevalence, awareness, treatment, and control of hypertension in the United States from 1988 to 2000?

Output: JAMA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that studies the prevalence, awareness, treatment, and control of hypertension in the United States from 1988 to 2000?. ### Response: JAMA.


Instruction: When was the JAMA's 290:199–206 issue published?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA's 290:199–206 issue published?. ### Response: 2003.


Instruction: What year did the Journal Circulation. 2014:130:1692–9 issue?

Output: 2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did the Journal Circulation. 2014:130:1692–9 issue?. ### Response: 2003.


Instruction: What is the name of the study that compares apoli-poprotein B levels and non-high-density lipoprotein cholesterol in subjects with hypertriglyceridemia?

Output: SAFARI Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that compares apoli-poprotein B levels and non-high-density lipoprotein cholesterol in subjects with hypertriglyceridemia?. ### Response: SAFARI Trial.


Instruction: What does the SAFARI Trial compare?

Output: apoli-poprotein B levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the SAFARI Trial compare?. ### Response: apoli-poprotein B levels.


Instruction: How many subjects were enrolled in the 2016 ACC study?

Output: 68:92–125

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many subjects were enrolled in the 2016 ACC study?. ### Response: 68:92–125.


Instruction: What is the role of non-statin therapies for LDL-cholesterol lowering in the management of atherosclerotic cardiovascular disease risk?

Output: ACC expert consensus decision pathway

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the role of non-statin therapies for LDL-cholesterol lowering in the management of atherosclerotic cardiovascular disease risk?. ### Response: ACC expert consensus decision pathway.


Instruction: What was the report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents?

Output: pathway on the role of non-statin therapies for LDL-cholesterol lowering in the management of atherosclerotic cardiovascular disease risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents?. ### Response: pathway on the role of non-statin therapies for LDL-cholesterol lowering in the management of atherosclerotic cardiovascular disease risk.


Instruction: What is a test in context: Lipoprotein(a): diagnosis, progno-sis, contro-versies, and emerging therapies?

Output: Tsimikas S.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a test in context: Lipoprotein(a): diagnosis, progno-sis, contro-versies, and emerging therapies?. ### Response: Tsimikas S..


Instruction: What is the name of the document that documents the force on Clinical Expert Consensus Documents?

Output: American College of Cardiology Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that documents the force on Clinical Expert Consensus Documents?. ### Response: American College of Cardiology Task Force.


Instruction: Who is the author of A Test in Context?

Output: Tsimikas S

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the author of A Test in Context?. ### Response: Tsimikas S.


Instruction: What is a risk prediction among women?

Output: cardiovascular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk prediction among women?. ### Response: cardiovascular.


Instruction: What is the Meta-analysis of data from 170 000 participants in 26 randomised trials?

Output: Efficacy and safety of more intensive lowering of LDL cholesterol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Meta-analysis of data from 170 000 participants in 26 randomised trials?. ### Response: Efficacy and safety of more intensive lowering of LDL cholesterol.


Instruction: How many people participated in 26 randomised trials?

Output: 170 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people participated in 26 randomised trials?. ### Response: 170 000.


Instruction: What is the name of the meta-analysis of statin trials that found low levels of ath-erogenic lipoproteins and the risk for cardiovascular events?

Output: Cholesterol Treatment Trialist’s (CTT) Collaboration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the meta-analysis of statin trials that found low levels of ath-erogenic lipoproteins and the risk for cardiovascular events?. ### Response: Cholesterol Treatment Trialist’s (CTT) Collaboration.


Instruction: What is the name of the 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk?

Output: TOS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk?. ### Response: TOS.


Instruction: What is the 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults?

Output: S3.1.1-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults?. ### Response: S3.1.1-2.


Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?

Output: 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines?. ### Response: 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk.


Instruction: What does the Task Force on Practice Guidelines and The Obesity Society do?

Output: management of overweight and obesity in adults

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Task Force on Practice Guidelines and The Obesity Society do?. ### Response: management of overweight and obesity in adults.


Instruction: What is a summary of American Heart Association diet and cardiovascular disease?

Output: lifestyle recommendations revision 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a summary of American Heart Association diet and cardiovascular disease?. ### Response: lifestyle recommendations revision 2006.


Instruction: What year was the American Heart Association diet and lifestyle recommendations revised?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the American Heart Association diet and lifestyle recommendations revised?. ### Response: 2006.


Instruction: What is the name of the systematic review of the evidence for Canada's physical activity guidelines for adults?

Output: Warburton DE, Charlesworth S, Ivey A, et al. A systematic review of the evidence for Canada’s physical activity guidelines for adults. Int J Behav Nutr Phys Act. 2010;7:39.3.1.2. Lifestyle Therapies and Metabolic Syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review of the evidence for Canada's physical activity guidelines for adults?. ### Response: Warburton DE, Charlesworth S, Ivey A, et al. A systematic review of the evidence for Canada’s physical activity guidelines for adults. Int J Behav Nutr Phys Act. 2010;7:39.3.1.2. Lifestyle Therapies and Metabolic Syndrome.


Instruction: What is the name of a systematic review and meta-analysis of longitudinal studies of Metabolic syndrome and risk of incident cardiovascular events and death?

Output: J Am Coll Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of a systematic review and meta-analysis of longitudinal studies of Metabolic syndrome and risk of incident cardiovascular events and death?. ### Response: J Am Coll Cardiol.


Instruction: What was the focus of the 2015 ACC/AHA/SCAI Focused Update on Primary PCI 1141?

Output: Randomized trial of complete versus lesion-only revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the 2015 ACC/AHA/SCAI Focused Update on Primary PCI 1141?. ### Response: Randomized trial of complete versus lesion-only revascularization.


Instruction: What is the name of the randomized trial of complete versus lesion-only revascularization?

Output: CvLPRIT trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of complete versus lesion-only revascularization?. ### Response: CvLPRIT trial.


Instruction: What is the CvLPRIT trial?

Output: Randomized trial of complete versus lesion-only revascularization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the CvLPRIT trial?. ### Response: Randomized trial of complete versus lesion-only revascularization.


Instruction: What was the J Am Coll Cardiol. 2015;65:963–72?

Output: Randomized trial of complete versus lesion-only revascularization in patients undergoing primary per -cutaneous coronary intervention for STEMI and multivessel Disease: the CvLPRIT trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the J Am Coll Cardiol. 2015;65:963–72?. ### Response: Randomized trial of complete versus lesion-only revascularization in patients undergoing primary per -cutaneous coronary intervention for STEMI and multivessel Disease: the CvLPRIT trial.


Instruction: How did the HORIZONS-AMI trial compare to other trials?

Output: analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the HORIZONS-AMI trial compare to other trials?. ### Response: analysis.


Instruction: What is the name of the revascularization and stents in acute myocardial infarction trial?

Output: HORIZONS-AMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the revascularization and stents in acute myocardial infarction trial?. ### Response: HORIZONS-AMI.


Instruction: When was the J Am Coll Cardiol 58:704-11?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 58:704-11?. ### Response: 2011.


Instruction: What was the long-term outcome in patients with ST segment elevation?

Output: major adverse cardiac events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the long-term outcome in patients with ST segment elevation?. ### Response: major adverse cardiac events.


Instruction: What is the name of the registry that provides insights into staged multivessel percutaneous revascularization strategies?

Output: REAL registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry that provides insights into staged multivessel percutaneous revascularization strategies?. ### Response: REAL registry.


Instruction: Catheter Cardiovasc Interv. 2014;84:912–22.

Output: multivessel percutaneous intervention in acute myocardial infarction: analysis from the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial. J Am Coll Cardiol. 2011;58:704–11. 20. Manari A, Varani E, Guastaroba P, et al. Long-term outcome in patients with ST segment elevation myocardial infarction and multivessel disease treated with culprit-only, immediate, or staged multivessel percutaneous revascularization strategies: insights from the REAL registry. Catheter Cardiovasc Interv. 2014;84:912–22. 21

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Catheter Cardiovasc Interv. 2014;84:912–22.. ### Response: multivessel percutaneous intervention in acute myocardial infarction: analysis from the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial. J Am Coll Cardiol. 2011;58:704–11. 20. Manari A, Varani E, Guastaroba P, et al. Long-term outcome in patients with ST segment elevation myocardial infarction and multivessel disease treated with culprit-only, immediate, or staged multivessel percutaneous revascularization strategies: insights from the REAL registry. Catheter Cardiovasc Interv. 2014;84:912–22. 21.


Instruction: What is a major adverse cardiac event during long-term follow-up?

Output: target-vessel versus  multi-vessel revascularisation in ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major adverse cardiac event during long-term follow-up?. ### Response: target-vessel versus  multi-vessel revascularisation in ST-elevation myocardial infarction.


Instruction: What type of coronary intervention is used for acute myocardial infarction?

Output: primary percutaneous

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of coronary intervention is used for acute myocardial infarction?. ### Response: primary percutaneous.


Instruction: What is the name of the study that investigated the use of multivessel percutaneous coronary interventions?

Output: HORIZONS-AMI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the use of multivessel percutaneous coronary interventions?. ### Response: HORIZONS-AMI.


Instruction: When was the last time a patient had a mechanical reperfusion procedure?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last time a patient had a mechanical reperfusion procedure?. ### Response: 2001.


Instruction: What type of intervention is used in ST-elevation myocardial infarction patients?

Output: staged percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of intervention is used in ST-elevation myocardial infarction patients?. ### Response: staged percutaneous coronary intervention.


Instruction: What is the name of the randomized trial of preventive angio-plasty?

Output: CvLPRIT trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial of preventive angio-plasty?. ### Response: CvLPRIT trial.


Instruction: How many people participated in the Randomized Trial of Preventive Angioplasty in 2013?

Output: 24

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people participated in the Randomized Trial of Preventive Angioplasty in 2013?. ### Response: 24.


Instruction: In what year did Catheter Cardiovasc Interv publish 72:927–33?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Catheter Cardiovasc Interv publish 72:927–33?. ### Response: 2008.


Instruction: What is the impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction?

Output: 25. Sorajja P, Gersh BJ, Cox DA, et al. Impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction?. ### Response: 25. Sorajja P, Gersh BJ, Cox DA, et al. Impact.


Instruction: What was the Eur Heart J. 2007;28:1709-16?

Output: Impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the Eur Heart J. 2007;28:1709-16?. ### Response: Impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction.


Instruction: What is the PRAGUE 13 trial?

Output: complete revascularization versus conservative strategy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PRAGUE 13 trial?. ### Response: complete revascularization versus conservative strategy.


Instruction: What is a patient with ST-elevation myocardial infarction diagnosed with?

Output: non-infarct-related coronary artery disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a patient with ST-elevation myocardial infarction diagnosed with?. ### Response: non-infarct-related coronary artery disease.


Instruction: What is the name of the PRAGUE 13 trial?

Output: PRAGUE-13-Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the PRAGUE 13 trial?. ### Response: PRAGUE-13-Trial.


Instruction: When was the PRGUE-13 trial accessed?

Output: September 10, 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the PRGUE-13 trial accessed?. ### Response: September 10, 2015.


Instruction: What type of vessel is versus multivessel and staged percutaneous coronary intervention?

Output: Culprit vessel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of vessel is versus multivessel and staged percutaneous coronary intervention?. ### Response: Culprit vessel.


Instruction: What is a pairwise and network meta-analysis of myocardial infarction?

Output: Culprit vessel only versus mul-tivessel and staged percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a pairwise and network meta-analysis of myocardial infarction?. ### Response: Culprit vessel only versus mul-tivessel and staged percutaneous coronary intervention.


Instruction: What is the J Am Coll Cardiol. 2011;58:692–703.

Output: a pairwise and network meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Coll Cardiol. 2011;58:692–703.. ### Response: a pairwise and network meta-analysis.


Instruction: How many Hypertension studies were conducted in June 2015?

Output: 1382

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Hypertension studies were conducted in June 2015?. ### Response: 1382.


Instruction: How many patients with LV dysfunction were included in the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study?

Output: 111

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with LV dysfunction were included in the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study?. ### Response: 111.


Instruction: What study was conducted in patients with chronic HF and mild symptoms?

Output: Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study was conducted in patients with chronic HF and mild symptoms?. ### Response: Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure.


Instruction: What is the acronym for Mild Patients Hospitalization and Survival Study in Heart Failure?

Output: EMPHASIS-HF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Mild Patients Hospitalization and Survival Study in Heart Failure?. ### Response: EMPHASIS-HF.


Instruction: In both RALES and EMPHASIS-HF, the majority of the subjects had what?

Output: IHD.2.1.6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In both RALES and EMPHASIS-HF, the majority of the subjects had what?. ### Response: IHD.2.1.6.


Instruction: What are CBs?

Output: Calcium Channel Blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are CBs?. ### Response: Calcium Channel Blockers.


Instruction: What was the primary prevention of cardio-vascular events with the dihydropyridine CCB amlodipine equivalent to?

Output: that produced by the diuretic chlorthalidone or the ACE inhibitor lisinopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary prevention of cardio-vascular events with the dihydropyridine CCB amlodipine equivalent to?. ### Response: that produced by the diuretic chlorthalidone or the ACE inhibitor lisinopril.


Instruction: What was superiority over a -blocker claimed in Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)?

Output: composite of cardiovascular death, resuscitated sudden death, nonfatal MI, nonfatal stroke, hospi-talization for HF, end-stage renal disease, renal death, or dou-bling of baseline serum creatinine concentration, sustained for at least a month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was superiority over a -blocker claimed in Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)?. ### Response: composite of cardiovascular death, resuscitated sudden death, nonfatal MI, nonfatal stroke, hospi-talization for HF, end-stage renal disease, renal death, or dou-bling of baseline serum creatinine concentration, sustained for at least a month.


Instruction: What is ASCOT?

Output: Anglo-Scandinavian Cardiac Outcomes Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ASCOT?. ### Response: Anglo-Scandinavian Cardiac Outcomes Trial.


Instruction: What was shown to be similar to that of a diuretic or a -blocker?

Output: Primary protection with verapamil-based therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was shown to be similar to that of a diuretic or a -blocker?. ### Response: Primary protection with verapamil-based therapy.


Instruction: In the CONVINCE study, what was the primary protection with verapamil-based therapy similar to?

Output: a diuretic (hydro-chlorothiazide) or a β-blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the CONVINCE study, what was the primary protection with verapamil-based therapy similar to?. ### Response: a diuretic (hydro-chlorothiazide) or a β-blocker.


Instruction: What is the Nordic Diltiazem?

Output: NORDIL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Nordic Diltiazem?. ### Response: NORDIL.


Instruction: What are alternatives to -blockers in the treatment of angina pectoris?

Output: CCBs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are alternatives to -blockers in the treatment of angina pectoris?. ### Response: CCBs.


Instruction: CCBs are not recommended for what?

Output: secondary cardiac pro-tection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CCBs are not recommended for what?. ### Response: secondary cardiac pro-tection.


Instruction: Why is pro-tection less effective than ACE inhibitors?

Output: futility for success and safety concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is pro-tection less effective than ACE inhibitors?. ### Response: futility for success and safety concerns.


Instruction: What is aliskiren a direct renin inhibitor?

Output: lowers BP alone or when added to other antihypertensive agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is aliskiren a direct renin inhibitor?. ### Response: lowers BP alone or when added to other antihypertensive agents.


Instruction: When was the Aliskiren Trial In Type 2 Diabetes Using Cardio-Renal Disease Endpoints (ALTITUDE) stopped?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Aliskiren Trial In Type 2 Diabetes Using Cardio-Renal Disease Endpoints (ALTITUDE) stopped?. ### Response: 2011.


Instruction: What was ALTITUDE comparing placebo with aliskiren 300 mg once daily added to background?

Output: ACE inhibitor or ARB ther -apy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was ALTITUDE comparing placebo with aliskiren 300 mg once daily added to background?. ### Response: ACE inhibitor or ARB ther -apy.


Instruction: What was the primary out-come of ALTITUDE?

Output: cardiovascular death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the primary out-come of ALTITUDE?. ### Response: cardiovascular death.


Instruction: What is the name of the ACE inhibitor or ARB ther -apy?

Output: lisinopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the ACE inhibitor or ARB ther -apy?. ### Response: lisinopril.


Instruction: What was the out-come in ALTITUDE?

Output: cardiovascular death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the out-come in ALTITUDE?. ### Response: cardiovascular death.


Instruction: How long did the trial last?

Output: at least a month

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the trial last?. ### Response: at least a month.


Instruction: What were the reasons for stopping the trial?

Output: futility for success and safety concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the reasons for stopping the trial?. ### Response: futility for success and safety concerns.


Instruction: Why was the trial futile?

Output: success and safety concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why was the trial futile?. ### Response: success and safety concerns.


Instruction: What was the number of patients experiencing a nonfatal stroke in the placebo group?

Output: 85

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the number of patients experiencing a nonfatal stroke in the placebo group?. ### Response: 85.


Instruction: The aliskiren group was what?

Output: 112

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The aliskiren group was what?. ### Response: 112.


Instruction: What percentage of the population used the Internet?

Output: 1382

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the population used the Internet?. ### Response: 1382.


Instruction: What was the unadjusted P value of 112?

Output: 0.04

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the unadjusted P value of 112?. ### Response: 0.04.


Instruction: What is a quantitative analysis of blood lipid and lipo-protein adaptations to exercise?

Output: Durstine JL, Grandjean PW, Davis PG, et al. Blood lipid and lipo-protein adaptations to exercise: a quantitative analysis. Sports Med.2001;31:1033–62.518. Leon AS, Sanchez OA. Response of blood lipids to exercise trainingalone or combined with dietary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a quantitative analysis of blood lipid and lipo-protein adaptations to exercise?. ### Response: Durstine JL, Grandjean PW, Davis PG, et al. Blood lipid and lipo-protein adaptations to exercise: a quantitative analysis. Sports Med.2001;31:1033–62.518. Leon AS, Sanchez OA. Response of blood lipids to exercise trainingalone or combined with dietary intervention.


Instruction: What are the main outcomes in moderate hypercholesterolemic, h ypertensivepatients randomized to?

Output: pravastatin vs usual care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the main outcomes in moderate hypercholesterolemic, h ypertensivepatients randomized to?. ### Response: pravastatin vs usual care.


Instruction: What is the name of the trial in which patients were randomized to pravastatin vs usual care?

Output: PROSPER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial in which patients were randomized to pravastatin vs usual care?. ### Response: PROSPER.


Instruction: When was the trial called?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the trial called?. ### Response: 2002.


Instruction: What is a major outcome in patients with hypercholesterolemic heart attack?

Output: randomized to pravastatin vs usual care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major outcome in patients with hypercholesterolemic heart attack?. ### Response: randomized to pravastatin vs usual care.


Instruction: What is atorvastatin used for in hypertensive patients?

Output: Prevention of coronary andstroke events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atorvastatin used for in hypertensive patients?. ### Response: Prevention of coronary andstroke events.


Instruction: What is ASCOT-LLA?

Output: iac Outcomes Trial—Lipid Lowering Arm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ASCOT-LLA?. ### Response: iac Outcomes Trial—Lipid Lowering Arm.


Instruction: What is the name of the multicentre randomised controlled trial?

Output: Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm(ASCOT-LLA):

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicentre randomised controlled trial?. ### Response: Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm(ASCOT-LLA):.


Instruction: What is pravastatin in elderly individuals at risk of vascular disease?

Output: PROSPER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is pravastatin in elderly individuals at risk of vascular disease?. ### Response: PROSPER.


Instruction: When was the Lancet 360?

Output: 2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet 360?. ### Response: 2002.


Instruction: How is non-high-density lipoproteincholesterol level measured?

Output: cardiovascular disease mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is non-high-density lipoproteincholesterol level measured?. ### Response: cardiovascular disease mortality.


Instruction: What is Gemfibrozil used for in the prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol?

Output: secondaryprevention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Gemfibrozil used for in the prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol?. ### Response: secondaryprevention.


Instruction: What is a predictor of cardiovascular disease mortality?

Output: Non-high-density lipoproteincholesterol level

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a predictor of cardiovascular disease mortality?. ### Response: Non-high-density lipoproteincholesterol level.


Instruction: What is the name of the group that studied coronary arterydisease?

Output: Veterans Affairs High-Density Lipo-protein Cholesterol Intervention Trial Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that studied coronary arterydisease?. ### Response: Veterans Affairs High-Density Lipo-protein Cholesterol Intervention Trial Study Group.


Instruction: When did N Engl J Med issue 331:1289–98.526?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med issue 331:1289–98.526?. ### Response: 2004.


Instruction: What did Brown G, Albers JJ, Fisher LD, et al. do?

Output: Regression

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Brown G, Albers JJ, Fisher LD, et al. do?. ### Response: Regression.


Instruction: What did the GISSIPrevenzionetrial do?

Output: Dietary supplementation with n-3 polyunsaturated fat ty acids andvitamin E after myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the GISSIPrevenzionetrial do?. ### Response: Dietary supplementation with n-3 polyunsaturated fat ty acids andvitamin E after myocardial infarction.


Instruction: When did the Lancet issue 354:447–55.528?

Output: 1999

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Lancet issue 354:447–55.528?. ### Response: 1999.


Instruction: What was the name of the study that examined the relationship between fish intake and coronary heart disease?

Output: Whelton SP, He J, Whelton PK, et al. Meta-analysis of observationalstudies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the study that examined the relationship between fish intake and coronary heart disease?. ### Response: Whelton SP, He J, Whelton PK, et al. Meta-analysis of observationalstudies.


Instruction: How long did simvastatin help reduce triglycerides in patients with coronary heart disease?

Output: one year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did simvastatin help reduce triglycerides in patients with coronary heart disease?. ### Response: one year.


Instruction: What was the effect of weight loss and sodium reduction intervention on blood pressure and hypertension?

Output: incidence in overweight people with high-normal blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the effect of weight loss and sodium reduction intervention on blood pressure and hypertension?. ### Response: incidence in overweight people with high-normal blood pressure.


Instruction: What are the effects of weight loss and sodium reduction on bloodpressure and hypertension incidence in overweight people with high-normal blood pressure?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects of weight loss and sodium reduction on bloodpressure and hypertension incidence in overweight people with high-normal blood pressure?. ### Response: Effects.


Instruction: What is the phaseII of the Trials of Hypertension Prevention?

Output: weight loss and sodium reduction intervention on bloodpressure and hypertension incidence in overweight people with high-normal blood pressure. The Trials of Hypertension Prevention, phaseII. The Trials of Hypertension Prevention Collaborative Re searchGroup. Arch Intern Med. 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the phaseII of the Trials of Hypertension Prevention?. ### Response: weight loss and sodium reduction intervention on bloodpressure and hypertension incidence in overweight people with high-normal blood pressure. The Trials of Hypertension Prevention, phaseII. The Trials of Hypertension Prevention Collaborative Re searchGroup. Arch Intern Med. 1997.


Instruction: What type of diabetic patients were hospitalized for non-ST-elevation acute coronary syndromes?

Output: Canadian

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetic patients were hospitalized for non-ST-elevation acute coronary syndromes?. ### Response: Canadian.


Instruction: What is the name of the multidetector computed tomography study that examined the prognostic implications of nonobstructive coronary plaques in patients with myocardial infarction?

Output: Kristensen

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multidetector computed tomography study that examined the prognostic implications of nonobstructive coronary plaques in patients with myocardial infarction?. ### Response: Kristensen.


Instruction: What is the name of the multidetector computed tomography study?

Output: Kristensen TS, Kofoed KF, Kuhl JT, et al. Prognostic implications of nonobstructive coronary plaques in patients with non-ST-segment eleva-tion myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multidetector computed tomography study?. ### Response: Kristensen TS, Kofoed KF, Kuhl JT, et al. Prognostic implications of nonobstructive coronary plaques in patients with non-ST-segment eleva-tion myocardial infarction.


Instruction: When was the J Am Coll Cardiol 58:502–9. 605. Sanchez PL, Morinigo JL, Pabon P, et al. Prognostic relations between inflammatory markers and mortality in diabetic patients with non-ST elevation acute coronary syndrome.

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol 58:502–9. 605. Sanchez PL, Morinigo JL, Pabon P, et al. Prognostic relations between inflammatory markers and mortality in diabetic patients with non-ST elevation acute coronary syndrome.. ### Response: 2011.


Instruction: What is the delay from symptom onset to hospital presentation for patients with non-ST-segment elevation myocardial infarction?

Output: Delay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the delay from symptom onset to hospital presentation for patients with non-ST-segment elevation myocardial infarction?. ### Response: Delay.


Instruction: When did the Arch Intern Med issue 170:1834-41?

Output: 2010

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the Arch Intern Med issue 170:1834-41?. ### Response: 2010.


Instruction: What was the outcome of acute coronary syndrome in patients with and without diabetes mellitus?

Output: high risk and under treated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the outcome of acute coronary syndrome in patients with and without diabetes mellitus?. ### Response: high risk and under treated.


Instruction: What is the difference between patients with and without diabetes mellitus?

Output: treatment and out-come

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between patients with and without diabetes mellitus?. ### Response: treatment and out-come.


Instruction: What are the differences between intensive versus conventional glu-cose control in critically ill patients?

Output: high risk and under treated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the differences between intensive versus conventional glu-cose control in critically ill patients?. ### Response: high risk and under treated.


Instruction: What is a report from the National Cardiovascular Data Registry?

Output: Trends in the prevalence and outcomes of radial and femoral approaches to percutaneous coronary intervention

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report from the National Cardiovascular Data Registry?. ### Response: Trends in the prevalence and outcomes of radial and femoral approaches to percutaneous coronary intervention.


Instruction: What are the trends in the prevalence and outcomes of radial and femoral approaches to percutaneous coronary intervention?

Output: National Cardiovascular Data Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the trends in the prevalence and outcomes of radial and femoral approaches to percutaneous coronary intervention?. ### Response: National Cardiovascular Data Registry.


Instruction: What is the difference between the radial and femoral approach for percutaneous coronary diagnostic and interven-tional procedures?

Output: prevalence and outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between the radial and femoral approach for percutaneous coronary diagnostic and interven-tional procedures?. ### Response: prevalence and outcomes.


Instruction: When did the J Am Coll Cardiol issue 44:349–56?

Output: 2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Am Coll Cardiol issue 44:349–56?. ### Response: 2004.


Instruction: What was the association of the arterial access site at angioplasty with transfusion and mortality?

Output: M.O.R.T.A.L study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the association of the arterial access site at angioplasty with transfusion and mortality?. ### Response: M.O.R.T.A.L study.


Instruction: What is the M.O.R.T.A.L study about?

Output: Association of the arterial access site at angioplasty with transfusion and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the M.O.R.T.A.L study about?. ### Response: Association of the arterial access site at angioplasty with transfusion and mortality.


Instruction: What does the study say about the arterial access site at angioplasty with transfusion and mortality?

Output: Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the study say about the arterial access site at angioplasty with transfusion and mortality?. ### Response: Association.


Instruction: What is the name of the prospective registry of acute ischaemic syndromes in the UK?

Output: PRAIS-UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective registry of acute ischaemic syndromes in the UK?. ### Response: PRAIS-UK.


Instruction: What is PRAIS-UK?

Output: prospective registry of acute ischaemic syndromes in the UK

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PRAIS-UK?. ### Response: prospective registry of acute ischaemic syndromes in the UK.


Instruction: How long did the SYNTAX trial last?

Output: 3-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did the SYNTAX trial last?. ### Response: 3-year.


Instruction: What was the focus of the 3-year trial?

Output: SYNTAX trial outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the 3-year trial?. ### Response: SYNTAX trial outcomes.


Instruction: Herz. 2012;37:281–6. 614.

Output: NTAX trial outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Herz. 2012;37:281–6. 614.. ### Response: NTAX trial outcomes.


Instruction: What is CARDia?

Output: Coronary Artery Revascularization in Diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is CARDia?. ### Response: Coronary Artery Revascularization in Diabetes.


Instruction: What is the name of the CARDia trial?

Output: Coronary Artery Revascularization in Diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the CARDia trial?. ### Response: Coronary Artery Revascularization in Diabetes.


Instruction: What is ARTS?

Output: Arterial Revascularization Therapies Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ARTS?. ### Response: Arterial Revascularization Therapies Study.


Instruction: How long does it take for patients to recover from coronary stenting or bypass surgery?

Output: Five-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for patients to recover from coronary stenting or bypass surgery?. ### Response: Five-year.


Instruction: What is the name of the randomized trial?

Output: Arterial Revascularization Therapies Study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized trial?. ### Response: Arterial Revascularization Therapies Study.


Instruction: When was the J Am Coll Cardiol.46:575–81?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol.46:575–81?. ### Response: 2005.


Instruction: What is the difference between a balloon versus a closed commissurotomy?

Output: Balloon valvuloplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between a balloon versus a closed commissurotomy?. ### Response: Balloon valvuloplasty.


Instruction: What are the results of a randomized trial?

Output: seven-year follow-up results

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of a randomized trial?. ### Response: seven-year follow-up results.


Instruction: What is the difference between balloon valvuloplasty and closed commissurotomy for mitral stenosis?

Output: Percutaneous balloon

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between balloon valvuloplasty and closed commissurotomy for mitral stenosis?. ### Response: Percutaneous balloon.


Instruction: What was the name of the prospective hemodynamic study conducted in 1991?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the prospective hemodynamic study conducted in 1991?. ### Response: Circulation.


Instruction: Who was the author of Percutaneous balloon vs. closed commisurotomies?

Output: Turi ZG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the author of Percutaneous balloon vs. closed commisurotomies?. ### Response: Turi ZG.


Instruction: When was the N Engl J Med published?

Output: 1994

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med published?. ### Response: 1994.


Instruction: What is the name of the prospective, randomized trial of percutaneous balloon versus surgical closed commissurotomy for mitral stenosis?

Output: Balloon valvuloplasty

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prospective, randomized trial of percutaneous balloon versus surgical closed commissurotomy for mitral stenosis?. ### Response: Balloon valvuloplasty.


Instruction: What year did Circulation. 1991.83:1179-85?

Output: 1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did Circulation. 1991.83:1179-85?. ### Response: 1991.


Instruction: How old are the results of patients after mitral valve commissurotomy?

Output: ≤ 50 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are the results of patients after mitral valve commissurotomy?. ### Response: ≤ 50 years.


Instruction: What is a single-center experience?

Output: Long-term (≤ 50 years) results of patients after mitral valve commissurotomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a single-center experience?. ### Response: Long-term (≤ 50 years) results of patients after mitral valve commissurotomy.


Instruction: When was the J Thorac Cardiovasc Surg. 143:S96–8?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Thorac Cardiovasc Surg. 143:S96–8?. ### Response: 2012.


Instruction: What is the acute effect of percutaneous mitral balloon valvuloplasty on atrial electromechanical delay and P-wave dispersion in patients with mitral stenosis?

Output: 210–5

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acute effect of percutaneous mitral balloon valvuloplasty on atrial electromechanical delay and P-wave dispersion in patients with mitral stenosis?. ### Response: 210–5.


Instruction: What does Aviles RJ, Nishimura RA, Pellikka PA, et al. use of stress?

Output: Doppler echocar -diography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Aviles RJ, Nishimura RA, Pellikka PA, et al. use of stress?. ### Response: Doppler echocar -diography.


Instruction: What is the use of stress Doppler echocar -diography in patients undergoing percutaneous mitral balloon valvotomy?

Output: Utility

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the use of stress Doppler echocar -diography in patients undergoing percutaneous mitral balloon valvotomy?. ### Response: Utility.


Instruction: When did J Am Soc Echocardiogr. 2001;14:676–81?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Soc Echocardiogr. 2001;14:676–81?. ### Response: 2001.


Instruction: What is a relationship between valve calcifica-tion and long-term results of percutaneous commissurotomy for rheumatic mitral stenosis?

Output: single-center experience

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship between valve calcifica-tion and long-term results of percutaneous commissurotomy for rheumatic mitral stenosis?. ### Response: single-center experience.


Instruction: What is the result of percutaneous mitral commissurotomy for?

Output: rheumatic mitral stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the result of percutaneous mitral commissurotomy for?. ### Response: rheumatic mitral stenosis.


Instruction: What is EAE/ASE recommendations for clinical practice?

Output: Echocardiographic assessment of valve stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is EAE/ASE recommendations for clinical practice?. ### Response: Echocardiographic assessment of valve stenosis.


Instruction: How does EAE assess valve stenosis?

Output: Echocardiographic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does EAE assess valve stenosis?. ### Response: Echocardiographic.


Instruction: What is a simple predictor of outcome after percu-taneous mitral balloon valvotomy?

Output: issural calcium

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simple predictor of outcome after percu-taneous mitral balloon valvotomy?. ### Response: issural calcium.


Instruction: What does Apostolakis EE, Baikoussis NG do?

Output: Methods of estimation of mitral valve re-gurgitation for the cardiac surgeon

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Apostolakis EE, Baikoussis NG do?. ### Response: Methods of estimation of mitral valve re-gurgitation for the cardiac surgeon.


Instruction: How does the cardiac surgeon estimate mitral valve re-gurgitation?

Output: Methods

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the cardiac surgeon estimate mitral valve re-gurgitation?. ### Response: Methods.


Instruction: What is the name of the surgeon who performed balloon mitral valvuloplasty in the United States for 13 years?

Output: Badheka

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the surgeon who performed balloon mitral valvuloplasty in the United States for 13 years?. ### Response: Badheka.


Instruction: How long has it been since the US began performing balloon cuticles?

Output: 13-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has it been since the US began performing balloon cuticles?. ### Response: 13-year.


Instruction: How many patients underwent percutaneous balloon mitral valvotomy?

Output: 130

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients underwent percutaneous balloon mitral valvotomy?. ### Response: 130.


Instruction: What was the success rate of 130 patients?

Output: Prediction of successful outcome in 130 patients undergoing percutaneous balloon mitral valvotomy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the success rate of 130 patients?. ### Response: Prediction of successful outcome in 130 patients undergoing percutaneous balloon mitral valvotomy.


Instruction: How many echocardiographic variables were related to outcome and the mechanism of dilatation?

Output: 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many echocardiographic variables were related to outcome and the mechanism of dilatation?. ### Response: 23.


Instruction: What is a sign of commissural calcifica- tion?

Output: Significance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a sign of commissural calcifica- tion?. ### Response: Significance.


Instruction: What is the name of the journal that dealt with dilatation?

Output: Br Heart J.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the journal that dealt with dilatation?. ### Response: Br Heart J..


Instruction: What is one of the research priorities identified by the panel?

Output: developing validated specific DOAC effect tests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the research priorities identified by the panel?. ### Response: developing validated specific DOAC effect tests.


Instruction: What can be performed quickly and ideally at the point of care?

Output: developing validated specific DOAC effect tests

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be performed quickly and ideally at the point of care?. ### Response: developing validated specific DOAC effect tests.


Instruction: What should LMWH or UFH be used for patients transitioning from DOAC to VKA?

Output: bridging therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should LMWH or UFH be used for patients transitioning from DOAC to VKA?. ### Response: bridging therapy.


Instruction: What should patients use until the INR is within the therapeutic range?

Output: overlapping DOAC therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients use until the INR is within the therapeutic range?. ### Response: overlapping DOAC therapy.


Instruction: What does the ASHguideline panel suggest for patients transitioning from DOAC to VKA?

Output: overlapping DOAC and VKA therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ASHguideline panel suggest for patients transitioning from DOAC to VKA?. ### Response: overlapping DOAC and VKA therapy.


Instruction: What is the conditional recommendation based on?

Output: very low certainty in the evidence about effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the conditional recommendation based on?. ### Response: very low certainty in the evidence about effects.


Instruction: How many studies did we find that included patients with atrialfibrillation, not VTE, transitioning from DOAC therapy to VKA therapy?

Output: 3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did we find that included patients with atrialfibrillation, not VTE, transitioning from DOAC therapy to VKA therapy?. ### Response: 3.


Instruction: What did three studies report about mortality outcomes?

Output: only in the group overlapping DOAC during the transitionto VKA114-116

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did three studies report about mortality outcomes?. ### Response: only in the group overlapping DOAC during the transitionto VKA114-116.


Instruction: How many studies reported mortality outcomes during the transition to VKA114-116?

Output: Three

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies reported mortality outcomes during the transition to VKA114-116?. ### Response: Three.


Instruction: 1 study reported development of what type of stroke115?

Output: hemorrhagic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1 study reported development of what type of stroke115?. ### Response: hemorrhagic.


Instruction: No studies reported outcomes related to what?

Output: quality-of-life impairment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No studies reported outcomes related to what?. ### Response: quality-of-life impairment.


Instruction: TheEtD framework is shown online at https://dbep.gradepro.org/profile/b1889d83-5875-453f-b047-fb742c25e43e What is the evidence profile in the EtD Framework?

Output: Benefits. For benefits

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: TheEtD framework is shown online at https://dbep.gradepro.org/profile/b1889d83-5875-453f-b047-fb742c25e43e What is the evidence profile in the EtD Framework?. ### Response: Benefits. For benefits.


Instruction: What is the benefit of LMWH-bridging therapy?

Output: increase the risk for VTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the benefit of LMWH-bridging therapy?. ### Response: increase the risk for VTE.


Instruction: What was not available for the 30-day follow-up period?

Output: deaths

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was not available for the 30-day follow-up period?. ### Response: deaths.


Instruction: How long was the follow-up period for VTE?

Output: 30-day

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the follow-up period for VTE?. ### Response: 30-day.


Instruction: What was the RR of LMWH-bridging therapy during the transition from DOAC to VKA compared with overlapping DOAC therapy?

Output: 5.58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of LMWH-bridging therapy during the transition from DOAC to VKA compared with overlapping DOAC therapy?. ### Response: 5.58.


Instruction: What was the RR of overlapping DOAC therapy?

Output: 5.58

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the RR of overlapping DOAC therapy?. ### Response: 5.58.