Instruction: The well-documented variation in practice of PCI across the United States has been what?

Output: Appropriate Indication for Elective PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The well-documented variation in practice of PCI across the United States has been what?. ### Response: Appropriate Indication for Elective PCI.


Instruction: What is the variation in practice of PCI across the United States?

Output: well-documented variation25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the variation in practice of PCI across the United States?. ### Response: well-documented variation25.


Instruction: Prior attempts to construct performance measures have not relied heavily on what?

Output: AUC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Prior attempts to construct performance measures have not relied heavily on what?. ### Response: AUC.


Instruction: The writing committee approached the creation of what measure cautiously?

Output: Appropriate Indication for Elective PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The writing committee approached the creation of what measure cautiously?. ### Response: Appropriate Indication for Elective PCI.


Instruction: How did the committee approach the creation of this measure?

Output: cautiously

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the committee approach the creation of this measure?. ### Response: cautiously.


Instruction: What did this measure do to maximize its value to users without leading to unintended consequences?

Output: cautiously

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did this measure do to maximize its value to users without leading to unintended consequences?. ### Response: cautiously.


Instruction: Where did we focus on elective PCIs that occur in nonacute settings?

Output: To optimize our opportunity to improve care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where did we focus on elective PCIs that occur in nonacute settings?. ### Response: To optimize our opportunity to improve care.


Instruction: Analyses of what have shown that the vast majority of procedures are classified as appropriate according to AUC?

Output: PCIs performed in acute settings

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Analyses of what have shown that the vast majority of procedures are classified as appropriate according to AUC?. ### Response: PCIs performed in acute settings.


Instruction: What did we aim to harmonize the document with?

Output: recently published guidelines and AUC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we aim to harmonize the document with?. ### Response: recently published guidelines and AUC.


Instruction: Why is the AUC not superimposable on their definitions?

Output: the AUC cannot possibly include every conceivable patient presentation of appropriateness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is the AUC not superimposable on their definitions?. ### Response: the AUC cannot possibly include every conceivable patient presentation of appropriateness.


Instruction: What is the first reason for the non-superimposability of the performance measure?

Output: it is acknowledged that the AUC cannot possibly include every conceivable patient presentation of appropriateness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the first reason for the non-superimposability of the performance measure?. ### Response: it is acknowledged that the AUC cannot possibly include every conceivable patient presentation of appropriateness.


Instruction: The AUC are created via a modified Delphi?

Output: experts reach consensus after being presented with specific clini-cal scenarios that focus on coronary anatomy, symptoms, current medical therapy, and noninvasive studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The AUC are created via a modified Delphi?. ### Response: experts reach consensus after being presented with specific clini-cal scenarios that focus on coronary anatomy, symptoms, current medical therapy, and noninvasive studies.


Instruction: How are the AUCs created?

Output: via a modified Delphi approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are the AUCs created?. ### Response: via a modified Delphi approach.


Instruction: What is the modified Delphi approach?

Output: experts reach consensus after being presented with specific clini-cal scenarios that focus on coronary anatomy, symptoms, current medical therapy, and noninvasive studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the modified Delphi approach?. ### Response: experts reach consensus after being presented with specific clini-cal scenarios that focus on coronary anatomy, symptoms, current medical therapy, and noninvasive studies.


Instruction: AUC and guidelines exist for what?

Output: PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: AUC and guidelines exist for what?. ### Response: PCI.


Instruction: What do the guidelines for PCI categorize the usefulness of these procedures for in asymptomatic patients as?

Output: survival benefit

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do the guidelines for PCI categorize the usefulness of these procedures for in asymptomatic patients as?. ### Response: survival benefit.


Instruction: What is the Class IIb recommendation?

Output: “uncertain in patients with 2- or 3-vessel [coronary artery dis-ease] (with or without involvement of the proximal [left anterior descending] artery) or 1-vessel proximal [left anterior descending] disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Class IIb recommendation?. ### Response: “uncertain in patients with 2- or 3-vessel [coronary artery dis-ease] (with or without involvement of the proximal [left anterior descending] artery) or 1-vessel proximal [left anterior descending] disease.


Instruction: What do experts vary in their assessments of the usefulness of PCI in this setting from uncertain to appropriate?

Output: AUC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do experts vary in their assessments of the usefulness of PCI in this setting from uncertain to appropriate?. ### Response: AUC.


Instruction: How does PCI in this setting change from uncertain to appropriate?

Output: vary

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does PCI in this setting change from uncertain to appropriate?. ### Response: vary.


Instruction: What are some additional factors described previously?

Output: current medical therapy, noninvasive studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some additional factors described previously?. ### Response: current medical therapy, noninvasive studies.


Instruction: Who is Professor of Medicine, Division of Cardiology, Medical Director for Quality, Vanderbilt Heart & Vascular Institute, and Associate Medical Director, Cardiovascular ICUN?

Output: Sidney C. Smith Jr

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Professor of Medicine, Division of Cardiology, Medical Director for Quality, Vanderbilt Heart & Vascular Institute, and Associate Medical Director, Cardiovascular ICUN?. ### Response: Sidney C. Smith Jr.


Instruction: What is the name of the professor of medicine at the University of North Carolina, Chapel Hill?

Output: Sidney C. Smith Jr

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor of medicine at the University of North Carolina, Chapel Hill?. ### Response: Sidney C. Smith Jr.


Instruction: Who is Professor of Cardiovascular Research at Baylor College of Medicine?

Output: Salim S. Virani

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Professor of Cardiovascular Research at Baylor College of Medicine?. ### Response: Salim S. Virani.


Instruction: What is Michael E. DeBakey VA Medical Center's job title?

Output: Staff Cardiologist and Investigator

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Michael E. DeBakey VA Medical Center's job title?. ### Response: Staff Cardiologist and Investigator.


Instruction: What is the name of the professor and chief of Rush Medical College?

Output: Kim A. Williams Sr Rush Medical College—James B. Herrick

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the professor and chief of Rush Medical College?. ### Response: Kim A. Williams Sr Rush Medical College—James B. Herrick.


Instruction: When was this article downloaded?

Output: May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article downloaded?. ### Response: May 1, 2023.


Instruction: What does the absence of an identified disease-causing genetic muta-tion not do?

Output: exclude the presence of disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the absence of an identified disease-causing genetic muta-tion not do?. ### Response: exclude the presence of disease.


Instruction: What do desmosomal mutation positive individuals do not develop?

Output: disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do desmosomal mutation positive individuals do not develop?. ### Response: disease.


Instruction: What does the absence of an identified disease-causing genetic muta-tion not exclude?

Output: the presence of disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the absence of an identified disease-causing genetic muta-tion not exclude?. ### Response: the presence of disease.


Instruction: What are ongoing monitoring and decision-making done based on?

Output: the clinical phenotype

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ongoing monitoring and decision-making done based on?. ### Response: the clinical phenotype.


Instruction: Genotyping is frequent-ly most useful when what is identified in the proband?

Output: a pathogenic mutation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Genotyping is frequent-ly most useful when what is identified in the proband?. ### Response: a pathogenic mutation.


Instruction: What can be applied to relatives who are in a preclinical phase?

Output: screening

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be applied to relatives who are in a preclinical phase?. ### Response: screening.


Instruction: What can institu-tion of lifestyle changes, therapy, or ongoing monitoring for those who are gene mutation positive?

Output: Genotyping is frequent-ly most useful when a pathogenic mutation is identified in the proband, such that screening can be applied to relatives who are in a preclinical phase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can institu-tion of lifestyle changes, therapy, or ongoing monitoring for those who are gene mutation positive?. ### Response: Genotyping is frequent-ly most useful when a pathogenic mutation is identified in the proband, such that screening can be applied to relatives who are in a preclinical phase.


Instruction: How old are young patients without structural heart disease with unexplained cardiac arrest, near drowning, or recurrent exertional syncope?

Output: (<40 years of age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old are young patients without structural heart disease with unexplained cardiac arrest, near drowning, or recurrent exertional syncope?. ### Response: (<40 years of age.


Instruction: What may be important to identify an inherited arrhythmia syndrome as a likely cause?

Output: genetic testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be important to identify an inherited arrhythmia syndrome as a likely cause?. ### Response: genetic testing.


Instruction: What are some of the implications of positive genotyping?

Output: psychological, financial, employment, disability, and life insurance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the implications of positive genotyping?. ### Response: psychological, financial, employment, disability, and life insurance.


Instruction: What is a consideration in deciding to proceed with genetic testing?

Output: clinical phenotype

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a consideration in deciding to proceed with genetic testing?. ### Response: clinical phenotype.


Instruction: What is posi-tive genotyping?

Output: psychological, financial, employment, disability, and life insurance implications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is posi-tive genotyping?. ### Response: psychological, financial, employment, disability, and life insurance implications.


Instruction: What does balancing privacy of health care information for the proband with the right to know for family members mean?

Output: the ability to provide appropriate communication of information to all potentially affected family mem-bers can be challenging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does balancing privacy of health care information for the proband with the right to know for family members mean?. ### Response: the ability to provide appropriate communication of information to all potentially affected family mem-bers can be challenging.


Instruction: What are some of the factors that affect genetic counseling?

Output: family dynamics, geographic proximity, and access to health care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the factors that affect genetic counseling?. ### Response: family dynamics, geographic proximity, and access to health care.


Instruction: What is a possible combination of genetic counseling and medical guidance?

Output: genetic testing would be beneficial on an individual basis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a possible combination of genetic counseling and medical guidance?. ### Response: genetic testing would be beneficial on an individual basis.


Instruction: What can be combined with medical guidance to balance the decision as to whether genetic testing would be beneficial on an individual basis?

Output: genetic counseling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be combined with medical guidance to balance the decision as to whether genetic testing would be beneficial on an individual basis?. ### Response: genetic counseling.


Instruction: Invasive Testing: Cardiac Catheterization or CT AngiographyRecommendation for Invasives Imaging: Cardiology or CT Aniography?

Output: 10.1161/CIR.0000000000000549

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Invasive Testing: Cardiac Catheterization or CT AngiographyRecommendation for Invasives Imaging: Cardiology or CT Aniography?. ### Response: 10.1161/CIR.0000000000000549.


Instruction: What type of imaging is recommended for patients who have recovered from surgery?

Output: Invasive Imaging: Cardiac CatheterizationCOR LOE RecommendationI C-EO1.  In patients who have recovered from unexplained SCA, CT or invasive coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of imaging is recommended for patients who have recovered from surgery?. ### Response: Invasive Imaging: Cardiac CatheterizationCOR LOE RecommendationI C-EO1.  In patients who have recovered from unexplained SCA, CT or invasive coronary angiography.


Instruction: What is useful in patients who have recovered from unexplained SCA?

Output: CT or invasive coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is useful in patients who have recovered from unexplained SCA?. ### Response: CT or invasive coronary angiography.


Instruction: What is helpful to confirm the presence or absence of ischemic heart disease and guide decisions for myocardial revascularization?

Output: CT or invasive coronary angiography

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is helpful to confirm the presence or absence of ischemic heart disease and guide decisions for myocardial revascularization?. ### Response: CT or invasive coronary angiography.


Instruction: What is required of a writing committee member who develops new RWI during his or her tenure on the writing committee?

Output: notify staff in writing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is required of a writing committee member who develops new RWI during his or her tenure on the writing committee?. ### Response: notify staff in writing.


Instruction: Who reviews these statements peri-odically?

Output: the Task Force and by members of the writing committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reviews these statements peri-odically?. ### Response: the Task Force and by members of the writing committee.


Instruction: What are the authors and peer reviewer RWI relevant to the doc-ument included in?

Output: the appendices

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the authors and peer reviewer RWI relevant to the doc-ument included in?. ### Response: the appendices.


Instruction: What does the writing committee members' comprehensive disclosure information include?

Output: RWI not relevant to the pres-ent document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the writing committee members' comprehensive disclosure information include?. ### Response: RWI not relevant to the pres-ent document.


Instruction: What is available online at http://circ.ahajournals.org/lookup/suppl/doi:10.1161/01.cir.0000441966.31451.3f/-/DC1?

Output: comprehensive disclosure information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is available online at http://circ.ahajournals.org/lookup/suppl/doi:10.1161/01.cir.0000441966.31451.3f/-/DC1?. ### Response: comprehensive disclosure information.


Instruction: Who supported the work of the writing committee?

Output: the ACC, the AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who supported the work of the writing committee?. ### Response: the ACC, the AHA.


Instruction: The ACC, AHA, and AMA were supported exclusively without what?

Output: commer -cial support

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ACC, AHA, and AMA were supported exclusively without what?. ### Response: commer -cial support.


Instruction: Members of what committee volunteered their time for this effort?

Output: writing committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Members of what committee volunteered their time for this effort?. ### Response: writing committee.


Instruction: Meetings of the writing committee were confidential and attended only by who?

Output: committee members and staff

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Meetings of the writing committee were confidential and attended only by who?. ### Response: committee members and staff.


Instruction: What does the ACC, AHA, SCAI, AMA-PCPI, and NCQA have in common?

Output: multiple measurable domains

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ACC, AHA, SCAI, AMA-PCPI, and NCQA have in common?. ### Response: multiple measurable domains.


Instruction: What is the goal of a performance measurement system?

Output: identification of a set of measures targeting a specific patient population observed over a particular time period

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the goal of a performance measurement system?. ### Response: identification of a set of measures targeting a specific patient population observed over a particular time period.


Instruction: The ACC/AHA Task Force on Performance Measures has outlined what?

Output: a set of mandatory sequential steps

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The ACC/AHA Task Force on Performance Measures has outlined what?. ### Response: a set of mandatory sequential steps.


Instruction: What has outlined a set of mandatory sequential steps?

Output: the ACC/AHA Task Force on Performance Measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has outlined a set of mandatory sequential steps?. ### Response: the ACC/AHA Task Force on Performance Measures.


Instruction: What outline how the steps were applied by the present writing committee?

Output: The following sections

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What outline how the steps were applied by the present writing committee?. ### Response: The following sections.


Instruction: What did the writing committee seek to identify that are most meaningful to patients undergoing PCI?

Output: structures, processes, and outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the writing committee seek to identify that are most meaningful to patients undergoing PCI?. ### Response: structures, processes, and outcomes.


Instruction: What was a key aspect of the committee's work?

Output: to determine outcomes that are most relevant for patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a key aspect of the committee's work?. ### Response: to determine outcomes that are most relevant for patients.


Instruction: What is included in the measure specifications at http://www.ama-assn.org/apps/listserv/x-check/qmeasure.cgi?

Output: A complete list of the desirable outcomes identified by the writing committee and how they relate to the proposed process measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is included in the measure specifications at http://www.ama-assn.org/apps/listserv/x-check/qmeasure.cgi?. ### Response: A complete list of the desirable outcomes identified by the writing committee and how they relate to the proposed process measures.


Instruction: Who identified and articulated the rel-evant dimensions of care that should be evaluated?

Output: the writing committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who identified and articulated the rel-evant dimensions of care that should be evaluated?. ### Response: the writing committee.


Instruction: What was each potential performance measure categorised into?

Output: its relevant dimension of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was each potential performance measure categorised into?. ### Response: its relevant dimension of care.


Instruction: How did the classification facilitate identification of areas in care?

Output: evidence was lacking and prevented duplication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the classification facilitate identification of areas in care?. ### Response: evidence was lacking and prevented duplication.


Instruction: What facilitated identification of areas in which evidence was lacking?

Output: Classification into dimensions of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What facilitated identification of areas in which evidence was lacking?. ### Response: Classification into dimensions of care.


Instruction: What prevented duplication of Table 2?

Output: Classification into dimensions of care

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What prevented duplication of Table 2?. ### Response: Classification into dimensions of care.


Instruction: What is the 2018 ACHD Guideline?

Output: Stout et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2018 ACHD Guideline?. ### Response: Stout et al.


Instruction: What are useful for initial and follow-up evaluation of patients with ACHD?

Output: Table 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are useful for initial and follow-up evaluation of patients with ACHD?. ### Response: Table 33.


Instruction: What is ACHD with PAH?

Output: pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ACHD with PAH?. ### Response: pulmonary hypertension.


Instruction: What is defined as elevation of mean pulmonary arterial pressure to  25 mm Hg at rest?

Output: Pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is defined as elevation of mean pulmonary arterial pressure to  25 mm Hg at rest?. ### Response: Pulmonary hypertension.


Instruction: How is Pulmonary hypertension classified?

Output: on the ba-sis of the presumed mechanism

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is Pulmonary hypertension classified?. ### Response: on the ba-sis of the presumed mechanism.


Instruction: What is the elevation of pulmonary venous pressure referred to as?

Output: postcapillary pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the elevation of pulmonary venous pressure referred to as?. ### Response: postcapillary pulmonary hypertension.


Instruction: What is PAH classified by developmental or acquired anatomic ab-normalities?

Output: decreased pulmonary arterial capacitance, impedance, or stenosis throughout the pulmonary arte-rial vascular bed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is PAH classified by developmental or acquired anatomic ab-normalities?. ### Response: decreased pulmonary arterial capacitance, impedance, or stenosis throughout the pulmonary arte-rial vascular bed.


Instruction: What was the initial research model of triggered PAH?

Output: left-to-right shunting

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the initial research model of triggered PAH?. ### Response: left-to-right shunting.


Instruction: What can be caused by, or associated with, ACHD?

Output: pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be caused by, or associated with, ACHD?. ### Response: pulmonary hypertension.


Instruction: What can be caused by, or associated with, any of the factors described above?

Output: pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be caused by, or associated with, any of the factors described above?. ### Response: pulmonary hypertension.


Instruction: Effective therapies may be spe-cific to the primary mechanism of what in a given patient?

Output: pulmonary hyperten-sion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Effective therapies may be spe-cific to the primary mechanism of what in a given patient?. ### Response: pulmonary hyperten-sion.


Instruction: Patients with CHD should have thorough investigation for all potential contributing etiologies to what?

Output: pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with CHD should have thorough investigation for all potential contributing etiologies to what?. ### Response: pulmonary hypertension.


Instruction: What may require spe-cific therapy if best clinical outcomes are achieved?

Output: pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may require spe-cific therapy if best clinical outcomes are achieved?. ### Response: pulmonary hypertension.


Instruction: Adverse effects of pulmonary hypertension therapies in patients with ACHD may differ from those noted in other patients?

Output: Effective therapies may be spe-cific to the primary mechanism of pulmonary hyperten-sion in a given patient

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Adverse effects of pulmonary hypertension therapies in patients with ACHD may differ from those noted in other patients?. ### Response: Effective therapies may be spe-cific to the primary mechanism of pulmonary hyperten-sion in a given patient.


Instruction: What can cause Shunt-related PAH in patients with ACHD to de-velop in the pre- or perioperative period but also develop years to decades after closure of defects?

Output: pulmonary resistance rises above systemic resistance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can cause Shunt-related PAH in patients with ACHD to de-velop in the pre- or perioperative period but also develop years to decades after closure of defects?. ### Response: pulmonary resistance rises above systemic resistance.


Instruction: What mechanisms for development of PAH may include ge-netic factors?

Output: environmental exposures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What mechanisms for development of PAH may include ge-netic factors?. ### Response: environmental exposures.


Instruction: What may contribute to the development of PAH?

Output: ge-netic factors and environmental exposures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may contribute to the development of PAH?. ### Response: ge-netic factors and environmental exposures.


Instruction: What are two factors that contribute to PAH development?

Output: ge-netic factors and environmental exposures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are two factors that contribute to PAH development?. ### Response: ge-netic factors and environmental exposures.


Instruction: Severity of what can range from incidentally noted mild pressure and resistance elevation to profound systemic or supra-systemic levels of PA pressure?

Output: PAH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Severity of what can range from incidentally noted mild pressure and resistance elevation to profound systemic or supra-systemic levels of PA pressure?. ### Response: PAH.


Instruction: What may develop as pulmonary resistance rises above systemic resistance?

Output: shunt reversal and cyanosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may develop as pulmonary resistance rises above systemic resistance?. ### Response: shunt reversal and cyanosis.


Instruction: What is Eisenmenger syndrome?

Output: pulmonary resistance rises above systemic resistance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Eisenmenger syndrome?. ### Response: pulmonary resistance rises above systemic resistance.


Instruction: Where are recommendations on who should perform surgeries?

Output: Section 3.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where are recommendations on who should perform surgeries?. ### Response: Section 3.3.


Instruction: Where is Section 3.4 for rec-ommendations on diagnostic evaluation?

Output: Section 3.3 for recommendations on who should perform surgeries, cardiac catheterization, and other procedures in these patients; Section 3.4 for rec-ommendations on diagnostic evaluation; and Table 33

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Section 3.4 for rec-ommendations on diagnostic evaluation?. ### Response: Section 3.3 for recommendations on who should perform surgeries, cardiac catheterization, and other procedures in these patients; Section 3.4 for rec-ommendations on diagnostic evaluation; and Table 33.


Instruction: Where is Table 33 for routine testing and follow-up intervals?

Output: Section 3.3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Table 33 for routine testing and follow-up intervals?. ### Response: Section 3.3.


Instruction: Patients with ACHD with what?

Output: pulmonary hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with ACHD with what?. ### Response: pulmonary hypertension.


Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

Output: Otto et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: Otto et al.


Instruction: What is a proposal to optimize care for patients with valvular heart disease?

Output: AATS/ACC/ASE/SCAI/STS ex-pert consensus systems of care document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a proposal to optimize care for patients with valvular heart disease?. ### Response: AATS/ACC/ASE/SCAI/STS ex-pert consensus systems of care document.


Instruction: What is the name of the joint report of the American Association for Thoracic Surgery?

Output: AATS/ACC/ASE/SCAI/STS ex-pert consensus systems of care document

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the joint report of the American Association for Thoracic Surgery?. ### Response: AATS/ACC/ASE/SCAI/STS ex-pert consensus systems of care document.


Instruction: What criteria is used to evaluate the hemodynamic durability of transcath-eter aortic valves?

Output: Valve Academic Research Consor -tium-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What criteria is used to evaluate the hemodynamic durability of transcath-eter aortic valves?. ### Response: Valve Academic Research Consor -tium-2.


Instruction: What is the current Valve Academic Research Consor -tium-2 criteria?

Output: Hemodynamic durability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the current Valve Academic Research Consor -tium-2 criteria?. ### Response: Hemodynamic durability.


Instruction: What is deterioration after transcatheter aortic valve implantation?

Output: Structural valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is deterioration after transcatheter aortic valve implantation?. ### Response: Structural valve.


Instruction: What are the results of the CHOICE randomized clinical trial?

Output: 5-Year outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the CHOICE randomized clinical trial?. ### Response: 5-Year outcomes.


Instruction: How long does it take to achieve 1-Year outcomes?

Output: 23

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to achieve 1-Year outcomes?. ### Response: 23.


Instruction: What is the name of the study that examined patient values and preferences on transcatheter or surgical aortic valve replacement therapy?

Output: CHOICE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined patient values and preferences on transcatheter or surgical aortic valve replacement therapy?. ### Response: CHOICE.


Instruction: What year was the J Am Coll Cardiol 66:791–800?

Output: 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the J Am Coll Cardiol 66:791–800?. ### Response: 2015.


Instruction: What did the American College of Cardiology Task Force on Clinical Expert Consensus Documents report on?

Output: ACC expert consensus decision pathway for transcatheter aortic valve replacement in the man-agement of adults with aortic stenosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology Task Force on Clinical Expert Consensus Documents report on?. ### Response: ACC expert consensus decision pathway for transcatheter aortic valve replacement in the man-agement of adults with aortic stenosis.


Instruction: What was the name of the group that authored the 2017 ACC expert consensus decision pathway?

Output: American College of Cardiology Task Force

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the group that authored the 2017 ACC expert consensus decision pathway?. ### Response: American College of Cardiology Task Force.


Instruction: What year did JACC Cardiovasc Interv. 2020:13:1071–82?

Output: 2017

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did JACC Cardiovasc Interv. 2020:13:1071–82?. ### Response: 2017.


Instruction: What is the difference between balloon-expandable and self-expanding valves?

Output: 5-Year outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between balloon-expandable and self-expanding valves?. ### Response: 5-Year outcomes.


Instruction: What is the difference between Sapien 3 balloon-expandable versus Evolut R self-expandable transcatheter aortic valve implantation?

Output: Impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between Sapien 3 balloon-expandable versus Evolut R self-expandable transcatheter aortic valve implantation?. ### Response: Impact.


Instruction: What is a propensity-matched comparison from a nationwide analysis?

Output: Balloon-expandable versus self-expanding transcatheter aortic valve replacement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a propensity-matched comparison from a nationwide analysis?. ### Response: Balloon-expandable versus self-expanding transcatheter aortic valve replacement.


Instruction: What is a propensity-matched comparison of transcatheter aortic valve replacement versus self-expanding?

Output: Balloon-expandable versus self-expanding transcatheter aortic valve replacement: a propensity-matched comparison from the FRANCE-TAVI Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a propensity-matched comparison of transcatheter aortic valve replacement versus self-expanding?. ### Response: Balloon-expandable versus self-expanding transcatheter aortic valve replacement: a propensity-matched comparison from the FRANCE-TAVI Registry.


Instruction: What is the name of the FRANCE-TAVI Registry?

Output: Balloon-expandable versus self-expanding transcatheter aortic valve replacement: a propensity-matched comparison

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the FRANCE-TAVI Registry?. ### Response: Balloon-expandable versus self-expanding transcatheter aortic valve replacement: a propensity-matched comparison.


Instruction: How long does it take for patients to have a valve replacement?

Output: 1-Year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for patients to have a valve replacement?. ### Response: 1-Year.


Instruction: What is the name of the registry used for transcatheter aortic valve replacement in patients with low-flow, low-gradient stenosis?

Output: FRANCE-TAVI Registry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the registry used for transcatheter aortic valve replacement in patients with low-flow, low-gradient stenosis?. ### Response: FRANCE-TAVI Registry.


Instruction: When did the TOPAS-TAVI registry become available?

Output: 2018

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the TOPAS-TAVI registry become available?. ### Response: 2018.


Instruction: What is the name of the 2021 guideline for the Secondary Prevention of Ischemic Stroke?

Output: Stroke. 2021;52:e364–e467 . DOI: 10.1161/STR.0000000000000375 July 2021  e441CLINICAL STATEMENTS   AND GUIDELINESKleindorfer et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2021 guideline for the Secondary Prevention of Ischemic Stroke?. ### Response: Stroke. 2021;52:e364–e467 . DOI: 10.1161/STR.0000000000000375 July 2021  e441CLINICAL STATEMENTS   AND GUIDELINESKleindorfer et al.


Instruction: What is the name of the VA Tennessee Valley Healthcare System?

Output: Christianne Roumie

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the VA Tennessee Valley Healthcare System?. ### Response: Christianne Roumie.


Instruction: Who is the founder of Boston University Medical Center?

Output: Julie  Shulman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the founder of Boston University Medical Center?. ### Response: Julie  Shulman.


Instruction: How many women’s health initiatives are there?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many women’s health initiatives are there?. ### Response: None.


Instruction: Who does Best Doctors, Inc. review?

Output: Ebix, MedLink, Med-scape

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who does Best Doctors, Inc. review?. ### Response: Ebix, MedLink, Med-scape.


Instruction: What is the name of the university that does not have a Women’s Health Initiative?

Output: Richard ZweiflerTulane University

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the university that does not have a Women’s Health Initiative?. ### Response: Richard ZweiflerTulane University.


Instruction: What is the name of the University of Ottawa's heart institute?

Output: University of Ottawa Heart Institute

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the University of Ottawa's heart institute?. ### Response: University of Ottawa Heart Institute.


Instruction: Who is the head of the faculty at McMaster University?

Output: Brian Silver

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the head of the faculty at McMaster University?. ### Response: Brian Silver.


Instruction: What is one of the names of the universities that are not part of the Bayer group?

Output: Richard ZweiflerTulane University

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the names of the universities that are not part of the Bayer group?. ### Response: Richard ZweiflerTulane University.


Instruction: What is the name of the university?

Output: Tulane University

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the university?. ### Response: Tulane University.


Instruction: Who is the head of the University of Texas?

Output: Babu Welch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the head of the University of Texas?. ### Response: Babu Welch.


Instruction: What is one of the universities that is not affiliated with the University?

Output: Richard ZweiflerTulane University

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the universities that is not affiliated with the University?. ### Response: Richard ZweiflerTulane University.


Instruction: Ingelheim*None None None None WhatUniversity of Texas Southwestern Medi-cal CenterNo None Stryker Neuro-vascular*No None Medtronic; Microven-tion*NoNovo Nordisk*Daniel Woo University of CincinnatiNIH*No Necessarily None NoneBradford WorrallAmerican Academy of NeurologyNIH None None

Output: Boehringer Ingelheim*None None None NoneBabu Welch

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ingelheim*None None None None WhatUniversity of Texas Southwestern Medi-cal CenterNo None Stryker Neuro-vascular*No None Medtronic; Microven-tion*NoNovo Nordisk*Daniel Woo University of CincinnatiNIH*No Necessarily None NoneBradford WorrallAmerican Academy of NeurologyNIH None None. ### Response: Boehringer Ingelheim*None None None NoneBabu Welch.


Instruction: What is the name of the American Academy of Neurology?

Output: American Academy of NeurologyNIH†

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the American Academy of Neurology?. ### Response: American Academy of NeurologyNIH†.


Instruction: Who is the head of the Yale School of Medicine?

Output: Henry Klar Yaggi

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the head of the Yale School of Medicine?. ### Response: Henry Klar Yaggi.


Instruction: What does the table below represent?

Output: relationships of reviewers that may be perceived as actual or reasonably perceived conflicts of interest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the table below represent?. ### Response: relationships of reviewers that may be perceived as actual or reasonably perceived conflicts of interest.


Instruction: What does the Disclosure Ques-tionnaire report as actual or reasonably perceived conflicts of interest?

Output: relationships of reviewers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Disclosure Ques-tionnaire report as actual or reasonably perceived conflicts of interest?. ### Response: relationships of reviewers.


Instruction: What is a relationship considered to be if the person receives $5 000 or more during a 12-month period?

Output: significant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if the person receives $5 000 or more during a 12-month period?. ### Response: significant.


Instruction: How much of the fair market value of an entity does the person own?

Output: $5 000 or more

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the fair market value of an entity does the person own?. ### Response: $5 000 or more.


Instruction: What is the term for a person who owns 5% or more of the voting stock or share?

Output: significant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the term for a person who owns 5% or more of the voting stock or share?. ### Response: significant.


Instruction: What is the fair market value of the entity?

Output: $5 000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the fair market value of the entity?. ### Response: $5 000.


Instruction: What is a relationship considered to be if it is less than "significant"?

Output: modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if it is less than "significant"?. ### Response: modest.


Instruction: Who is required to recuse themselves from voting on sections to which their specific relationships with industry and other entities may apply?

Output: Writing committee members

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is required to recuse themselves from voting on sections to which their specific relationships with industry and other entities may apply?. ### Response: Writing committee members.


Instruction: Who reported payments to Dr. Dearani in 2016 regarding research for the Sorin Group?

Output: CMS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who reported payments to Dr. Dearani in 2016 regarding research for the Sorin Group?. ### Response: CMS.


Instruction: In what year did Dearani discuss research for the Sorin Group and Cormatrix?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Dearani discuss research for the Sorin Group and Cormatrix?. ### Response: 2016.


Instruction: Who disagreed with Dearani's 2016 report?

Output: CMS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who disagreed with Dearani's 2016 report?. ### Response: CMS.


Instruction: What was affirmed in the sections authored by Dr. Dearani?

Output: there was no implication of any influence of industry

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was affirmed in the sections authored by Dr. Dearani?. ### Response: there was no implication of any influence of industry.


Instruction: What is the acronym for the American College of Cardiology?

Output: ACC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology?. ### Response: ACC.


Instruction: What does AHA stand for?

Output: American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does AHA stand for?. ### Response: American Heart Association.


Instruction: Where is COACH located?

Output: Columbus Ohio Adult Congenital Heart

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is COACH located?. ### Response: Columbus Ohio Adult Congenital Heart.


Instruction: Which university is home to UCLA?

Output: University of California, Los Angeles

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which university is home to UCLA?. ### Response: University of California, Los Angeles.


Instruction: On what date was the Financial BenefitExpert WitnessVoting Recusals by SectionDownloaded from http://ahajournals.org by?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On what date was the Financial BenefitExpert WitnessVoting Recusals by SectionDownloaded from http://ahajournals.org by?. ### Response: April 28, 2023.


Instruction: What does PINNACLE stand for?

Output: Practice INNova-tion And CLinical Excellence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does PINNACLE stand for?. ### Response: Practice INNova-tion And CLinical Excellence.


Instruction: What does the ACCF recommend?

Output: use of programs such as the AHA’sGet With The Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the ACCF recommend?. ### Response: use of programs such as the AHA’sGet With The Guidelines.


Instruction: What is important for a healthcare provider to implement the therapies according to their class of recommendation?

Output: if the patient has recentlyexperienced an acute event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is important for a healthcare provider to implement the therapies according to their class of recommendation?. ### Response: if the patient has recentlyexperienced an acute event.


Instruction: What does the healthcare provider assess for patient compliance with?

Output: these therapies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the healthcare provider assess for patient compliance with?. ### Response: these therapies.


Instruction: What can be found in the ACCF/AHA guideline for manage-ment of patients undergoing PCI?

Output: Discussion of the literature andsupporting references

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be found in the ACCF/AHA guideline for manage-ment of patients undergoing PCI?. ### Response: Discussion of the literature andsupporting references.


Instruction: What guideline will help with patient compliance with these therapies in each patient encounter?

Output: Get With The Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What guideline will help with patient compliance with these therapies in each patient encounter?. ### Response: Get With The Guidelines.


Instruction: What is the AHA/American Stroke Association's guideline for the prevention of stroke in patients with stroke or transient ischemic attack?

Output: 46

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHA/American Stroke Association's guideline for the prevention of stroke in patients with stroke or transient ischemic attack?. ### Response: 46.


Instruction: Who should exercise judgment in initiating the various recommendations if the patient has peripheral artery disease?

Output: the healthcare provider

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should exercise judgment in initiating the various recommendations if the patient has peripheral artery disease?. ### Response: the healthcare provider.


Instruction: What should the patient do if he or she has recently experienced an acute event?

Output: exercise judgment in initi-ating the various recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the patient do if he or she has recently experienced an acute event?. ### Response: exercise judgment in initi-ating the various recommendations.


Instruction: When was the Circulation November 29, 2011?

Output: 2464

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation November 29, 2011?. ### Response: 2464.


Instruction: What type of heart failure is treated with NICE 2018?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart failure is treated with NICE 2018?. ### Response: Chronic Heart Failure.


Instruction: What is the ISBN number of the study intervention and comparison?

Output: 978 -1-4731 -3093 -7 161

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ISBN number of the study intervention and comparison?. ### Response: 978 -1-4731 -3093 -7 161.


Instruction: What percentage of LVEF is 40%?

Output: ≤40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of LVEF is 40%?. ### Response: ≤40%.


Instruction: What is the difference between 9 and 15 g/dL (men) and 9 and 13.5 g /dl (women)?

Output: ≤40%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the difference between 9 and 15 g/dL (men) and 9 and 13.5 g /dl (women)?. ### Response: ≤40%.


Instruction: How long was the study?

Output: 16 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the study?. ### Response: 16 weeks.


Instruction: Change in peak VO 2  Change in 6 minute walk test distance?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Change in peak VO 2  Change in 6 minute walk test distance?. ### Response: Chronic Heart Failure.


Instruction: What is the median of the KCCQ clinical summary score?

Output: IQR  Toblli 2007336

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the median of the KCCQ clinical summary score?. ### Response: IQR  Toblli 2007336.


Instruction: What was the IQR of the Toblli 2007336?

Output: median

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the IQR of the Toblli 2007336?. ### Response: median.


Instruction: How much iron did the Infusion of IV iron equivalent to for 5 weeks?

Output: 200 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much iron did the Infusion of IV iron equivalent to for 5 weeks?. ### Response: 200 mg.


Instruction: What is a matching placebo?

Output: saline solution

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a matching placebo?. ### Response: saline solution.


Instruction: How many HF outpatients with ID, anaemia and CKD were matched?

Output: 60

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many HF outpatients with ID, anaemia and CKD were matched?. ### Response: 60.


Instruction: What was the LVEF  35%?

Output: ≤ 35%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the LVEF  35%?. ### Response: ≤ 35%.


Instruction: For men, what was the Hb 12.5 g/dl?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: For men, what was the Hb 12.5 g/dl?. ### Response: <.


Instruction: What is MLWHFQ?

Output: Quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is MLWHFQ?. ### Response: Quality of life.


Instruction: How many patients were originally recruited and analysed?

Output: 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were originally recruited and analysed?. ### Response: 40.


Instruction: How many patients were initially recruited and analysis published?

Output: 40

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were initially recruited and analysis published?. ### Response: 40.


Instruction: What was the initial study duration?

Output: 16 weeks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the initial study duration?. ### Response: 16 weeks.


Instruction: What does the addition of niacin to statin therapy improve?

Output: high-density lipoprotein cholesterol levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the addition of niacin to statin therapy improve?. ### Response: high-density lipoprotein cholesterol levels.


Instruction: What does statin do?

Output: improves high-density lipoprotein cholesterol levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does statin do?. ### Response: improves high-density lipoprotein cholesterol levels.


Instruction: When did J Am Coll Cardiol. 2012;62:1909-1910?

Output: 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Am Coll Cardiol. 2012;62:1909-1910?. ### Response: 2013.


Instruction: What is the name of the procedure that results in aorto-saphenous vein bypass narrowing late after coronary artery bypass grafting?

Output: Am J Cardiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the procedure that results in aorto-saphenous vein bypass narrowing late after coronary artery bypass grafting?. ### Response: Am J Cardiol.


Instruction: When was the file downloaded from http://ahajournals.org by?

Output: April 26, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the file downloaded from http://ahajournals.org by?. ### Response: April 26, 2023.


Instruction: Who is the current Chair-Elect of the AHA Task Force?

Output: Patrick T. O’Gara

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the current Chair-Elect of the AHA Task Force?. ### Response: Patrick T. O’Gara.


Instruction: What is the title of the current chair-elect?

Output: Patrick T. O’Gara

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the title of the current chair-elect?. ### Response: Patrick T. O’Gara.


Instruction: Who is a past chair?

Output: Jonathan L. Halperin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a past chair?. ### Response: Jonathan L. Halperin.


Instruction: What is Kim K. Birtcher's specialty?

Output: PharmD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Kim K. Birtcher's specialty?. ### Response: PharmD.


Instruction: What is Bi-ykem Bozkurt's profession?

Output: MD, PhD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Bi-ykem Bozkurt's profession?. ### Response: MD, PhD.


Instruction: Who is Ralph G. Brindis?

Output: MD, MPH, MACC*

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Ralph G. Brindis?. ### Response: MD, MPH, MACC*.


Instruction: Where is Lesley H. Cur-tis?

Output: PhD, FAHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Lesley H. Cur-tis?. ### Response: PhD, FAHA.


Instruction: Who is the President of the American College of Cardiology?

Output: Mary Norine Walsh

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the President of the American College of Cardiology?. ### Response: Mary Norine Walsh.


Instruction: Who was the Chief Executive Officer of American College Cardiology in 2007?

Output: Shalom Jacobovitz

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was the Chief Executive Officer of American College Cardiology in 2007?. ### Response: Shalom Jacobovitz.


Instruction: What is the name of the MD, FACC?

Output: José Joglar

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the MD, FACC?. ### Response: José Joglar.


Instruction: Who is the President of the FACC?

Output: Mary Norine Walsh

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the President of the FACC?. ### Response: Mary Norine Walsh.


Instruction: What is William J. Oetgen's job title?

Output: Executive Vice President

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is William J. Oetgen's job title?. ### Response: Executive Vice President.


Instruction: Who is a Director of Guideline Strategy and Operations?

Output: Katherine Sheehan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a Director of Guideline Strategy and Operations?. ### Response: Katherine Sheehan.


Instruction: Who is the Director of Guideline Methodology and Policy?

Output: Lisa Bradfield

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Director of Guideline Methodology and Policy?. ### Response: Lisa Bradfield.


Instruction: What is the name of the person who is the Chief Science and Medicine Officer of the American Heart Association?

Output: Rose Marie Robertson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who is the Chief Science and Medicine Officer of the American Heart Association?. ### Response: Rose Marie Robertson.


Instruction: Who is the Chief Science and Medicine Officer?

Output: Rose Marie Robertson

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Chief Science and Medicine Officer?. ### Response: Rose Marie Robertson.


Instruction: What is the Senior Vice Presi-dent in the Office of Science Operations?

Output: Gayle R. Whitman

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Senior Vice Presi-dent in the Office of Science Operations?. ### Response: Gayle R. Whitman.


Instruction: Who approved this document?

Output: American College of Cardiology Clinical Policy Approval Committee, the American Heart Association Science Advisory and Coordinating Com-mittee, the American Heart Association Executive Committee, and the Heart Failure Society of America Executive Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who approved this document?. ### Response: American College of Cardiology Clinical Policy Approval Committee, the American Heart Association Science Advisory and Coordinating Com-mittee, the American Heart Association Executive Committee, and the Heart Failure Society of America Executive Committee.


Instruction: What committee approved the Cardiology Clinical Policy Approval Committee in April 2017?

Output: American College

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What committee approved the Cardiology Clinical Policy Approval Committee in April 2017?. ### Response: American College.


Instruction: What is available with this article at http://circ.ahajournals.org/lookup/suppl?

Output: The Data Supplement

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is available with this article at http://circ.ahajournals.org/lookup/suppl?. ### Response: The Data Supplement.


Instruction: What is the name of the data supplement that is available with this article?

Output: The Comprehensive RWI Data Supplement table

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the data supplement that is available with this article?. ### Response: The Comprehensive RWI Data Supplement table.


Instruction: What journal has this article been copublished in?

Output: Journal of the American College of Cardiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What journal has this article been copublished in?. ### Response: Journal of the American College of Cardiology.


Instruction: Where is this article available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is this article available?. ### Response: http://circ.ahajournals.org.


Instruction: What is the American College of Cardiology's web site?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the American College of Cardiology's web site?. ### Response: www.acc.org.


Instruction: What are the websites of the American Heart Association and the Heart Failure Society of America?

Output: World Wide Web sites of the American College of Cardiology (www.acc.org), the American Heart Association (professional.heart.org), and the Heart Failure Society of America (www.hfsa.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the websites of the American Heart Association and the Heart Failure Society of America?. ### Response: World Wide Web sites of the American College of Cardiology (www.acc.org), the American Heart Association (professional.heart.org), and the Heart Failure Society of America (www.hfsa.org.


Instruction: Where is a copy of the document available?

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is a copy of the document available?. ### Response: http://professional.heart.org/statements.


Instruction: What does the “By Publication Date” link do?

Output: A copy of the document is available at http://professional.heart.org/statements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the “By Publication Date” link do?. ### Response: A copy of the document is available at http://professional.heart.org/statements.


Instruction: To purchase additional reprints, call 843-216-2533.

Output: kelle.ramsay

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: To purchase additional reprints, call 843-216-2533.. ### Response: kelle.ramsay.


Instruction: What is the maximum dose ofcandesartan in proteinuric renal disease?

Output: Supramaximal

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum dose ofcandesartan in proteinuric renal disease?. ### Response: Supramaximal.


Instruction: What does Ruggenenti P, Perticucci E, Cravedi P do in relation to CKD?

Output: remission clinics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Ruggenenti P, Perticucci E, Cravedi P do in relation to CKD?. ### Response: remission clinics.


Instruction: What type of nephropathies are associated with angiotensin convertingenzyme insertion/deletion polymorphism?

Output: indiabetic and nondiabetic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of nephropathies are associated with angiotensin convertingenzyme insertion/deletion polymorphism?. ### Response: indiabetic and nondiabetic.


Instruction: What is the effect of mineralocorticoid receptorantagonists on proteinuria?

Output: progression of chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of mineralocorticoid receptorantagonists on proteinuria?. ### Response: progression of chronic kidney disease.


Instruction: What is the effect of mineralocorticoid receptorantagonists on proteinuria and progression of chronic kidney disease?

Output: a systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of mineralocorticoid receptorantagonists on proteinuria and progression of chronic kidney disease?. ### Response: a systematic review and meta-analysis.


Instruction: BMC Nephrol. 2016;17:127.296.

Output: BMC Nephrol . 2016;17:127 .296. Cross NB, Webster AC, Masson P, et al. Antihypertensive treatment forkidney transplant recipients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: BMC Nephrol. 2016;17:127.296.. ### Response: BMC Nephrol . 2016;17:127 .296. Cross NB, Webster AC, Masson P, et al. Antihypertensive treatment forkidney transplant recipients.


Instruction: What is antihypertensive treatment for kidney transplant recipients?

Output: remission clinics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is antihypertensive treatment for kidney transplant recipients?. ### Response: remission clinics.


Instruction: What is the acronym for Kidney Disease: Improving Global Outcomes Transplant WorkGroup?

Output: KDIGO

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for Kidney Disease: Improving Global Outcomes Transplant WorkGroup?. ### Response: KDIGO.


Instruction: What does KDIGO stand for?

Output: Kidney Disease: Improving Global Outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does KDIGO stand for?. ### Response: Kidney Disease: Improving Global Outcomes.


Instruction: What does strict control of blood pressure do in pediatric renal transplant recipients?

Output: improved patient and graft survival

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does strict control of blood pressure do in pediatric renal transplant recipients?. ### Response: improved patient and graft survival.


Instruction: What are the baseline characteristics of patients from a randomized controlled trial?

Output: blood pressure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the baseline characteristics of patients from a randomized controlled trial?. ### Response: blood pressure.


Instruction: What does folic acid do for vascular outcome reduction intransplantation trial?

Output: death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does folic acid do for vascular outcome reduction intransplantation trial?. ### Response: death.


Instruction: What is the association of chronic kidney graft failure with recipient blood pressure?

Output: Collaborative transplant study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of chronic kidney graft failure with recipient blood pressure?. ### Response: Collaborative transplant study.


Instruction: When was the Collaborative transplant study conducted?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Collaborative transplant study conducted?. ### Response: 1998.


Instruction: What is associated with improved patient and graft survival after renaltransplantation?

Output: blood pressure control

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with improved patient and graft survival after renaltransplantation?. ### Response: blood pressure control.


Instruction: What is the Sci Rep 2019;9:10507.302?

Output: blood pressure control isassociated with improved patient and graft survival after renaltransplantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Sci Rep 2019;9:10507.302?. ### Response: blood pressure control isassociated with improved patient and graft survival after renaltransplantation.


Instruction: What is BP control for cardiovascular outcomes in SPRINT?

Output: intensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is BP control for cardiovascular outcomes in SPRINT?. ### Response: intensive.


Instruction: What is the name of the study in which Ambulatory blood pressure monitoring is performed in kidney transplant patients?

Output: RETENAL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study in which Ambulatory blood pressure monitoring is performed in kidney transplant patients?. ### Response: RETENAL.


Instruction: How long does it take to monitor blood pressure in renaltransplant patients?

Output: 24-h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take to monitor blood pressure in renaltransplant patients?. ### Response: 24-h.


Instruction: What is the name of the longitudinal study?

Output: Long-term blood pressuremonitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the longitudinal study?. ### Response: Long-term blood pressuremonitoring.


Instruction: How long is it taken for ambulatory blood pressure monitoring?

Output: 24-h

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long is it taken for ambulatory blood pressure monitoring?. ### Response: 24-h.


Instruction: What are the core outcomedomains for trials in kidney transplantation?

Output: StandardizedOutcomes in Nephrology-Kidney Transplantation ConsensusWorkshops

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the core outcomedomains for trials in kidney transplantation?. ### Response: StandardizedOutcomes in Nephrology-Kidney Transplantation ConsensusWorkshops.


Instruction: What is the name of the Standardized Outcomes in Nephrology-Kidney Transplantation ConsensusWorkshop?

Output: SONG-Tx

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Standardized Outcomes in Nephrology-Kidney Transplantation ConsensusWorkshop?. ### Response: SONG-Tx.


Instruction: What is the 2017 ACC/AHA/HFSA Heart Failure Focused UpdateCirculation. 2017;136:e137–e161 DOI: 10.1161/CIR.0000000000000509 August 8, 2017 e155CLINICAL STATEMENTS AND GUIDELINESand anemia: a pharmacokinetic and pharmacological investigation. J Cardiovasc Pharmacol. 2005;46:155–61.

Output: a pharmacokinetic and pharmacodynamic investigation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 ACC/AHA/HFSA Heart Failure Focused UpdateCirculation. 2017;136:e137–e161 DOI: 10.1161/CIR.0000000000000509 August 8, 2017 e155CLINICAL STATEMENTS AND GUIDELINESand anemia: a pharmacokinetic and pharmacological investigation. J Cardiovasc Pharmacol. 2005;46:155–61.. ### Response: a pharmacokinetic and pharmacodynamic investigation.


Instruction: Darbepoetin alfa in patients with anaemia and symptomatic

Output: heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Darbepoetin alfa in patients with anaemia and symptomatic. ### Response: heart failure.


Instruction: What is tolerability of darbepoetin alfa in patients with anaemia and symptomatic heart failure?

Output: safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tolerability of darbepoetin alfa in patients with anaemia and symptomatic heart failure?. ### Response: safety.


Instruction: What is the name of the randomized, double-blind, placebo-controlled trial that evaluated exercise tolerance in anemic patients?

Output: Ponikowski P , Anker SD, Szachniewicz J, et al. Effect of darbepoetin alfa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, double-blind, placebo-controlled trial that evaluated exercise tolerance in anemic patients?. ### Response: Ponikowski P , Anker SD, Szachniewicz J, et al. Effect of darbepoetin alfa.


Instruction: What is the name of the randomized, double-blind, placebo-controlled trial of heart failure?

Output: Ponikowski P , Anker SD, Szachniewicz J, et al. Effect of darbepoetin alfa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized, double-blind, placebo-controlled trial of heart failure?. ### Response: Ponikowski P , Anker SD, Szachniewicz J, et al. Effect of darbepoetin alfa.


Instruction: What did Silverberg DS, Wexler D, Sheps D, et al. study the effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron?

Output: randomized controlled study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Silverberg DS, Wexler D, Sheps D, et al. study the effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron?. ### Response: randomized controlled study.


Instruction: What is the name of the randomized controlled study?

Output: CHOIR trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized controlled study?. ### Response: CHOIR trial.


Instruction: When was the J Am Coll Cardiol.37:1775-80 published?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the J Am Coll Cardiol.37:1775-80 published?. ### Response: 2001.


Instruction: What is erythropoietin treat-ment in patients with chronic heart failure?

Output: exercise tolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is erythropoietin treat-ment in patients with chronic heart failure?. ### Response: exercise tolerance.


Instruction: How many dosing regimens of darbepoetin alfa do patients with heart failure and anaemia receive?

Output: two

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many dosing regimens of darbepoetin alfa do patients with heart failure and anaemia receive?. ### Response: two.


Instruction: What is the name of the double-blind, placebo-controlled study that evaluated the effect of two regimens?

Output: Randomized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the double-blind, placebo-controlled study that evaluated the effect of two regimens?. ### Response: Randomized.


Instruction: When was the Eur Heart J.28:2208–16?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur Heart J.28:2208–16?. ### Response: 2007.


Instruction: What is darbepoetin alfa used for in patients with symptomatic heart failure and anemia?

Output: exercise tolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is darbepoetin alfa used for in patients with symptomatic heart failure and anemia?. ### Response: exercise tolerance.


Instruction: What is the name of the randomized double-blind trial in 2008?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized double-blind trial in 2008?. ### Response: Circulation.


Instruction: How many patients were enrolled in the 2008 trial?

Output: 189

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were enrolled in the 2008 trial?. ### Response: 189.


Instruction: What is a side effect of recombinant erythropoietin?

Output: Venous thromboembolism and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a side effect of recombinant erythropoietin?. ### Response: Venous thromboembolism and mortality.


Instruction: What is another side effect?

Output: Venous thromboembolism and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another side effect?. ### Response: Venous thromboembolism and mortality.


Instruction: When was a meta-analysis of 57 studies done?

Output: 2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was a meta-analysis of 57 studies done?. ### Response: 2006.


Instruction: How many studies were included in the meta-analysis of 57 studies?

Output: 9353

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included in the meta-analysis of 57 studies?. ### Response: 9353.


Instruction: What is the name of the study that investigated darbepoe-tin alfa in type 2 diabetes and chronic kidney disease?

Output: Pfeffer

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated darbepoe-tin alfa in type 2 diabetes and chronic kidney disease?. ### Response: Pfeffer.


Instruction: What is the name of the study that evaluated epoetin-alpha dose and achieved hemoglobin outcomes?

Output: CHOIR trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated epoetin-alpha dose and achieved hemoglobin outcomes?. ### Response: CHOIR trial.


Instruction: When was the journal Kidney Int 74:791–8 published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the journal Kidney Int 74:791–8 published?. ### Response: 2008.


Instruction: What does intensive blood pressure lowering have on cardiovascular and renal outcome?

Output: Effects

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does intensive blood pressure lowering have on cardiovascular and renal outcome?. ### Response: Effects.


Instruction: What is the effect of intensive blood pressure lowering on cardiovascular and renal outcomes?

Output: updated systematic review and meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of intensive blood pressure lowering on cardiovascular and renal outcomes?. ### Response: updated systematic review and meta-analysis.


Instruction: When was the Lancet 387:435-43 published?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet 387:435-43 published?. ### Response: 2016.


Instruction: What are the effects of more vs. less inten-sive blood pressure?

Output: different achieved blood pressure levels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the effects of more vs. less inten-sive blood pressure?. ### Response: different achieved blood pressure levels.


Instruction: Blood pressure lowering and different achieved blood pressure levels - updated overview and meta-analyses of what?

Output: randomized trials

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Blood pressure lowering and different achieved blood pressure levels - updated overview and meta-analyses of what?. ### Response: randomized trials.


Instruction: Who acknowledged the existence of publication bias within this area?

Output: the committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who acknowledged the existence of publication bias within this area?. ### Response: the committee.


Instruction: What did the committee acknowledge?

Output: The presence of publication bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the committee acknowledge?. ### Response: The presence of publication bias.


Instruction: What made it difficult to ascertain the potential clinical benefit of an intervention?

Output: publication bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What made it difficult to ascertain the potential clinical benefit of an intervention?. ### Response: publication bias.


Instruction: The committee agreed that the intensification of more conventional methods of delivering care could be what?

Output: responsibilities potentially negatively impacting patient safety

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The committee agreed that the intensification of more conventional methods of delivering care could be what?. ### Response: responsibilities potentially negatively impacting patient safety.


Instruction: What do clinicians expect from imagers?

Output: coronary bypass surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do clinicians expect from imagers?. ### Response: coronary bypass surgery.


Instruction: How long does the Veterans Administration randomized trial of coronary bypass surgery for stable angina last?

Output: Eleven-year

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does the Veterans Administration randomized trial of coronary bypass surgery for stable angina last?. ### Response: Eleven-year.


Instruction: What is the name of the group that randomized the veterans administration Coronary Artery Bypass Surgery Cooperative Study Group?

Output: Veterans Adminis-tration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that randomized the veterans administration Coronary Artery Bypass Surgery Cooperative Study Group?. ### Response: Veterans Adminis-tration.


Instruction: What is the name of the Coronary ArterySurgery Study?

Output: CASS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Coronary ArterySurgery Study?. ### Response: CASS.


Instruction: When did the J Clin Invest publish the results of the CASS?

Output: 1983

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the J Clin Invest publish the results of the CASS?. ### Response: 1983.