Instruction: Patients with combined history of diabetes mellitus were excluded from what?

Output: ECASS III

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with combined history of diabetes mellitus were excluded from what?. ### Response: ECASS III.


Instruction: What is the NIHSS score of patients with very severe strokes?

Output: >25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the NIHSS score of patients with very severe strokes?. ### Response: >25.


Instruction: Why is there a perceived excessive risk of intracranial hemorrhage in patients with severe stroke?

Output: NIHSS score >25)

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is there a perceived excessive risk of intracranial hemorrhage in patients with severe stroke?. ### Response: NIHSS score >25).


Instruction: What does ASA stand for?

Output: American Stroke Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does ASA stand for?. ### Response: American Stroke Association.


Instruction: What may not be justified in practice?

Output: exclusion criteria

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may not be justified in practice?. ### Response: exclusion criteria.


Instruction: What is the maximum dose of IV alteplase over 60 minutes with initial 10% of the dose?

Output: 90 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the maximum dose of IV alteplase over 60 minutes with initial 10% of the dose?. ### Response: 90 mg.


Instruction: What can be beneficial in patients with AIS who awake with stroke symptoms or have unclear time of onset >4.5 hours from last known well?

Output: IV alteplase

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be beneficial in patients with AIS who awake with stroke symptoms or have unclear time of onset >4.5 hours from last known well?. ### Response: IV alteplase.


Instruction: How long from last known well or at baseline state is time of onset?

Output: >4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long from last known well or at baseline state is time of onset?. ### Response: >4.5 hours.


Instruction: How many patients with AIS were randomized in the WAKE-UP RCT?

Output: 503

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with AIS were randomized in the WAKE-UP RCT?. ### Response: 503.


Instruction: What lesion is smaller than one third of the MCA territory?

Output: DW-MRI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What lesion is smaller than one third of the MCA territory?. ### Response: DW-MRI.


Instruction: How long did IV alteplase take to treat stroke symptom recognition?

Output: 4.5 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did IV alteplase take to treat stroke symptom recognition?. ### Response: 4.5 hours.


Instruction: What was required to be eligible to be considered for AIS treatment?

Output: MRI mismatch between abnormal signal on DW-MRI and no visible signal change on FLAIR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was required to be eligible to be considered for AIS treatment?. ### Response: MRI mismatch between abnormal signal on DW-MRI and no visible signal change on FLAIR.


Instruction: How large were DW-MRI lesions?

Output: larger than one-third of the territory of the MCA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How large were DW-MRI lesions?. ### Response: larger than one-third of the territory of the MCA.


Instruction: How many wake-up strokes were there?

Output: Ninety-four percent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many wake-up strokes were there?. ### Response: Ninety-four percent.


Instruction: What was the median NIHSS score?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median NIHSS score?. ### Response: 6.


Instruction: How long did it take for symptoms to be recognized?

Output: ≈7 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for symptoms to be recognized?. ### Response: ≈7 hours.


Instruction: What was the last known well to symptom recognition?

Output: ≈7 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the last known well to symptom recognition?. ### Response: ≈7 hours.


Instruction: How long was alteplase administration?

Output: slightly over 10 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was alteplase administration?. ### Response: slightly over 10 hours.


Instruction: What percentage of the placebo group achieved the primary end point of an mRS score 0 to 1 at 90 days?

Output: 41.8%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the placebo group achieved the primary end point of an mRS score 0 to 1 at 90 days?. ### Response: 41.8%.


Instruction: What percentage of the placebo group had LVO of the intracranial internal carotid or proximal middle cerebral arteries?

Output: 20%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the placebo group had LVO of the intracranial internal carotid or proximal middle cerebral arteries?. ### Response: 20%.


Instruction: What is recommended for UA/NSTEMI patients for whom PCI is planned?

Output: A loading dose of P2Y12receptor inhibitor therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for UA/NSTEMI patients for whom PCI is planned?. ### Response: A loading dose of P2Y12receptor inhibitor therapy.


Instruction: What is the loading dose of P2Y12receptor inhibitor therapy?

Output: 6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the loading dose of P2Y12receptor inhibitor therapy?. ### Response: 6.


Instruction: What should be given as early as possible before or at the time of PCI32,73,74 (Level of Evidence: B)?

Output: Clopidogrel 600 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given as early as possible before or at the time of PCI32,73,74 (Level of Evidence: B)?. ### Response: Clopidogrel 600 mg.


Instruction: When should prasugrel be given no later than 1 hour after PCI?

Output: once coronary anatomy is defined

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should prasugrel be given no later than 1 hour after PCI?. ### Response: once coronary anatomy is defined.


Instruction: What should be given as early as possible before or at the time of PCI?

Output: Ticagrelor† 180 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given as early as possible before or at the time of PCI?. ### Response: Ticagrelor† 180 mg.


Instruction: What should the duration and maintenance dose of P2Y12receptor be?

Output: 2011 recommendationmodified

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the duration and maintenance dose of P2Y12receptor be?. ### Response: 2011 recommendationmodified.


Instruction: What should the duration and maintenance dose of P2Y12receptor inhibitor therapy be?

Output: 2011 recommendationmodified

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the duration and maintenance dose of P2Y12receptor inhibitor therapy be?. ### Response: 2011 recommendationmodified.


Instruction: What should be given for at least 12 months in UA/NSTEMI patients undergoing PCI?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given for at least 12 months in UA/NSTEMI patients undergoing PCI?. ### Response: clopidogrel.


Instruction: What should be given for at least 12 months?

Output: clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be given for at least 12 months?. ### Response: clopidogrel.


Instruction: What is the risk of morbidity because of bleeding outweighs the anticipated benefits?

Output: P2Y12receptor inhibitortherapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of morbidity because of bleeding outweighs the anticipated benefits?. ### Response: P2Y12receptor inhibitortherapy.


Instruction: What is another name for a P2Y12 receptorinhibitor?

Output: clopidogrel orticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for a P2Y12 receptorinhibitor?. ### Response: clopidogrel orticagrelor.


Instruction: What is a GPIIb/IIIa inhibitor?

Output: P2Y12receptor inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a GPIIb/IIIa inhibitor?. ### Response: P2Y12receptor inhibitor.


Instruction: What was clopidogrel replaced with?

Output: P2Y12” receptorinhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was clopidogrel replaced with?. ### Response: P2Y12” receptorinhibitor.


Instruction: What was the 2007 recommendationmodified?

Output: “clopidogrel”replaced with “P2Y12” receptorinhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2007 recommendationmodified?. ### Response: “clopidogrel”replaced with “P2Y12” receptorinhibitor.


Instruction: In UA/NSTEMI patients, what is reasonable to omit administration of?

Output: IVGP IIb/IIIa inhibitor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In UA/NSTEMI patients, what is reasonable to omit administration of?. ### Response: IVGP IIb/IIIa inhibitor.


Instruction: At least how many mg of clopidogrel was administered at least 6 hours earlier than planned catheterization or PCI?

Output: 300

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: At least how many mg of clopidogrel was administered at least 6 hours earlier than planned catheterization or PCI?. ### Response: 300.


Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary?

Output: Arnett et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who published the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary?. ### Response: Arnett et al.


Instruction: What is the name of the document that describes the primary prevention of cardiovascular disease?

Output: statin use guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the document that describes the primary prevention of cardiovascular disease?. ### Response: statin use guidelines.


Instruction: How many pages are in the document?

Output: e563–e595

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pages are in the document?. ### Response: e563–e595.


Instruction: Who wrote the document on the value of primordial and pri-mary prevention?

Output: Arnett

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who wrote the document on the value of primordial and pri-mary prevention?. ### Response: Arnett.


Instruction: What is the name of the policy statement from the American Heart Association?

Output: Task Force on Performance Measures and Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the policy statement from the American Heart Association?. ### Response: Task Force on Performance Measures and Task Force on Practice Guidelines.


Instruction: When was the Circulation.124:967-90 published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.124:967-90 published?. ### Response: 2011.


Instruction: What did the American College of Cardiology/American Heart Association report on?

Output: Task Force on Performance Measures and Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association report on?. ### Response: Task Force on Performance Measures and Task Force on Practice Guidelines.


Instruction: What is the name of the Task Force on Performance Measures and Practice Guidelines?

Output: American College of Cardiology/American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Task Force on Performance Measures and Practice Guidelines?. ### Response: American College of Cardiology/American Heart Association.


Instruction: When did Circulation issue 129:2329-45?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Circulation issue 129:2329-45?. ### Response: 2014.


Instruction: What was the cost-effectiveness of inten-sive versus standard blood-pressure control?

Output: 745–55

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the cost-effectiveness of inten-sive versus standard blood-pressure control?. ### Response: 745–55.


Instruction: What is the cost-effectiveness of hypertension therapy according to 2014 guidelines?

Output: S5-4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of hypertension therapy according to 2014 guidelines?. ### Response: S5-4.


Instruction: What is a systematic review of antihypertensive medicines?

Output: Cost-effectiveness analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of antihypertensive medicines?. ### Response: Cost-effectiveness analyses.


Instruction: What is a systematic review of?

Output: Cost-effectiveness analyses of antihypertensive medicines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a systematic review of?. ### Response: Cost-effectiveness analyses of antihypertensive medicines.


Instruction: What is the cost-effectiveness of intensive blood pressure management?

Output: Statin cost-effective-ness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of intensive blood pressure management?. ### Response: Statin cost-effective-ness.


Instruction: Who is Heller DJ?

Output: Coxson PG, Penko J

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Heller DJ?. ### Response: Coxson PG, Penko J.


Instruction: What are statin use guidelines for primary prevention of?

Output: coro-nary heart disease and stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are statin use guidelines for primary prevention of?. ### Response: coro-nary heart disease and stroke.


Instruction: Circulation. 2017;136:1087-98.

Output: intensive blood pressure management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 2017;136:1087-98.. ### Response: intensive blood pressure management.


Instruction: What is the cost-effectiveness and population impact of statins?

Output: primary prevention in adults aged 75 years or older in the United States

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness and population impact of statins?. ### Response: primary prevention in adults aged 75 years or older in the United States.


Instruction: What is the cost-effectiveness of statin in the United States for people at different vascular risk levels?

Output: cost-effective-ness

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cost-effectiveness of statin in the United States for people at different vascular risk levels?. ### Response: cost-effective-ness.


Instruction: What are the ABCDs of lifestyle counseling?

Output: JAMA Cardiol. 2016;1:505–6

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the ABCDs of lifestyle counseling?. ### Response: JAMA Cardiol. 2016;1:505–6.


Instruction: What is the APPENDIX 1. SEARCH CRITRIA 1. Patnode CD, Evans CV, Senger CA, et al.

Output: Behavioral counseling

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the APPENDIX 1. SEARCH CRITRIA 1. Patnode CD, Evans CV, Senger CA, et al.. ### Response: Behavioral counseling.


Instruction: What did the US Preventive Services Task Force update?

Output: evidence report and systematic review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the US Preventive Services Task Force update?. ### Response: evidence report and systematic review.


Instruction: When was the JAMA published?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 2016.


Instruction: What did LeBlanc ES, Patnode CD, Webber EM, et al do to prevent obesity related morbidity and mortality in adults?

Output: Behavioral and pharmaco-therapy weight loss interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did LeBlanc ES, Patnode CD, Webber EM, et al do to prevent obesity related morbidity and mortality in adults?. ### Response: Behavioral and pharmaco-therapy weight loss interventions.


Instruction: What is the name of the systematic review for the US Preventive Services Task Force?

Output: updated evidence report

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the systematic review for the US Preventive Services Task Force?. ### Response: updated evidence report.


Instruction: What was the 2008 recommendation for screening for abnormal glucose and type 2 diabetes?

Output: US Preventive Services Task Force Recommendation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 2008 recommendation for screening for abnormal glucose and type 2 diabetes?. ### Response: US Preventive Services Task Force Recommendation.


Instruction: What is the ACHD AP Classification S2.3-1?

Output: Mortality in adult congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACHD AP Classification S2.3-1?. ### Response: Mortality in adult congenital heart disease.


Instruction: What is Mortality in adult congenital heart disease?

Output: increased mortality risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Mortality in adult congenital heart disease?. ### Response: increased mortality risk.


Instruction: When did Eur Heart J. 2010:31:1220-9?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Eur Heart J. 2010:31:1220-9?. ### Response: 2008.


Instruction: What is exercise intolerance in adult congenital heart disease?

Output: comparative severity, correlates, and prognostic implication

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is exercise intolerance in adult congenital heart disease?. ### Response: comparative severity, correlates, and prognostic implication.


Instruction: What is the comparative severity, correlates, and prognostic implication of exercise?

Output: increased mortality risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the comparative severity, correlates, and prognostic implication of exercise?. ### Response: increased mortality risk.


Instruction: What is cyanosis related to?

Output: Abnormal venti-latory response to exercise in adults with congenital heart di-sease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is cyanosis related to?. ### Response: Abnormal venti-latory response to exercise in adults with congenital heart di-sease.


Instruction: What is the hemodynamic phenotype of the failing Fontan?

Output: Hemodynamic pheno-type

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the hemodynamic phenotype of the failing Fontan?. ### Response: Hemodynamic pheno-type.


Instruction: What is the hemodynamic pheno-type of the failing Fontan in an adult population?

Output: congenital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the hemodynamic pheno-type of the failing Fontan in an adult population?. ### Response: congenital.


Instruction: What is a multi-institutional study of arrhythmia burden in adults with surgically repaired tetralogy of Fallot?

Output: Circulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a multi-institutional study of arrhythmia burden in adults with surgically repaired tetralogy of Fallot?. ### Response: Circulation.


Instruction: What is a multicenter study of Sudden Death and defibrilla-tors in transposition of the great arteries with intra-atrial baffles?

Output: Circ Arrhythm Electrophysiol

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a multicenter study of Sudden Death and defibrilla-tors in transposition of the great arteries with intra-atrial baffles?. ### Response: Circ Arrhythm Electrophysiol.


Instruction: What is the name of the study that identifies adults using cardi-opulmonary exercise testing?

Output: Seattle Heart Failure Model

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that identifies adults using cardi-opulmonary exercise testing?. ### Response: Seattle Heart Failure Model.


Instruction: What does comprehensive use of cardi-opulmonary exercise testing identify?

Output: adults with congenital heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does comprehensive use of cardi-opulmonary exercise testing identify?. ### Response: adults with congenital heart disease.


Instruction: What does Circulation. 2012;125:250-9?

Output: Comprehensive use of cardi-opulmonary exercise testing identifies adults with congenital heart disease at increased mortality risk in the medium term

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Circulation. 2012;125:250-9?. ### Response: Comprehensive use of cardi-opulmonary exercise testing identifies adults with congenital heart disease at increased mortality risk in the medium term.


Instruction: Peak oxygen uptake, venti-latory efficiency and QRS-duration predict in patients late after what?

Output: surgical repair of tetralogy of Fallot

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Peak oxygen uptake, venti-latory efficiency and QRS-duration predict in patients late after what?. ### Response: surgical repair of tetralogy of Fallot.


Instruction: What predicts event free survival in patients late after surgical repair of tetralogy of Fallot?

Output: Peak oxygen uptake, venti-latory efficiency and QRS-duration

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What predicts event free survival in patients late after surgical repair of tetralogy of Fallot?. ### Response: Peak oxygen uptake, venti-latory efficiency and QRS-duration.


Instruction: Int J Cardiol. 2015;196:158–64.

Output: S2.3-10

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Int J Cardiol. 2015;196:158–64.. ### Response: S2.3-10.


Instruction: What does the Seattle Heart Failure Model identify adults with congenital heart disease at high risk of?

Output: poor outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the Seattle Heart Failure Model identify adults with congenital heart disease at high risk of?. ### Response: poor outcome.


Instruction: What type of heart disease is at high risk of poor outcome?

Output: congenital

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of heart disease is at high risk of poor outcome?. ### Response: congenital.


Instruction: What is the risk factor of coronary artery disease in adults with congenital heart disease and its rela-tion to traditional heart risk factors?

Output: Burden

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk factor of coronary artery disease in adults with congenital heart disease and its rela-tion to traditional heart risk factors?. ### Response: Burden.


Instruction: What is natriuretic peptide levels used to predict in adults with congenital heart disease?

Output: mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is natriuretic peptide levels used to predict in adults with congenital heart disease?. ### Response: mortality.


Instruction: When did Am J Cardiol. 2010:105:869–73?

Output: 2009

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Am J Cardiol. 2010:105:869–73?. ### Response: 2009.


Instruction: What is long-term survival, modes of death, and mortality?

Output: predictors of mortality in patients with Fontan surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is long-term survival, modes of death, and mortality?. ### Response: predictors of mortality in patients with Fontan surgery.


Instruction: What is the name of the surgeon who performed Fontan surgery?

Output: Khairy P

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the surgeon who performed Fontan surgery?. ### Response: Khairy P.


Instruction: When was the publication published?

Output: 2008

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the publication published?. ### Response: 2008.


Instruction: What was the title of the study?

Output: Sudden death and defibrilla-tors in transposition of the great arteries with intra-atrial baffles: a multicenter study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of the study?. ### Response: Sudden death and defibrilla-tors in transposition of the great arteries with intra-atrial baffles: a multicenter study.


Instruction: People have the right to be in volved in discussions and make informed decisions about what?

Output: t heir car e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: People have the right to be in volved in discussions and make informed decisions about what?. ### Response: t heir car e.


Instruction: NICE's inf ormation on making decisions about our care describes what right?

Output: All right s reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: NICE's inf ormation on making decisions about our care describes what right?. ### Response: All right s reserved.


Instruction: Making decisions using NICE guidelines explains ho w what we use?

Output: ords

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Making decisions using NICE guidelines explains ho w what we use?. ### Response: ords.


Instruction: What does NICE explain about prescribing medicines?

Output: off -label use

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NICE explain about prescribing medicines?. ### Response: off -label use.


Instruction: What are standar ds and laws?

Output: consent and mental capacity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are standar ds and laws?. ### Response: consent and mental capacity.


Instruction: What are some of the r ecommendations on measuring blood pr essur e and diagnosing h yper tension in his guideline?

Output: t hose wit h type  2 diabet es

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some of the r ecommendations on measuring blood pr essur e and diagnosing h yper tension in his guideline?. ### Response: t hose wit h type  2 diabet es.


Instruction: What type of diabetes are included in t o all adult s?

Output: type  2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabetes are included in t o all adult s?. ### Response: type  2.


Instruction: What type of diabet es is linked to NICE guidelines on chronic kidne y disease?

Output: type  1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of diabet es is linked to NICE guidelines on chronic kidne y disease?. ### Response: type  1.


Instruction: Hyper tension in pregnancy at point s in t he car e pat hway wher?

Output: treatment differs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hyper tension in pregnancy at point s in t he car e pat hway wher?. ### Response: treatment differs.


Instruction: What are the r ecommendations on tr eatment and monitoring applied t o adult s wit h type 2 diabet es?

Output: diagnosing and managing h yper tension in NICE's guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the r ecommendations on tr eatment and monitoring applied t o adult s wit h type 2 diabet es?. ### Response: diagnosing and managing h yper tension in NICE's guideline.


Instruction: What is NICE's guideline on diabetes?

Output: type  2 diabet es in adult s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE's guideline on diabetes?. ### Response: type  2 diabet es in adult s.


Instruction: What is NICE's guideline on type 2 diabet es in adult s?

Output: 1.1 Measuring b lood pr essur e 1.1.1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE's guideline on type 2 diabet es in adult s?. ### Response: 1.1 Measuring b lood pr essur e 1.1.1.


Instruction: What do healt hcare professionals taking blood pr ssur e measur ements have adequat training and periodic r eview of?

Output: t heir performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do healt hcare professionals taking blood pr ssur e measur ements have adequat training and periodic r eview of?. ### Response: t heir performance.


Instruction: What should a person have adequat e initial training and periodic r eview of their performance?

Output: healt hcare professionals taking blood pr essur e measur ement s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should a person have adequat e initial training and periodic r eview of their performance?. ### Response: healt hcare professionals taking blood pr essur e measur ement s.


Instruction: 1.1.2 Because aut omat ed de vices ma y not measur e blood pr essur ably if there is pulse irregularity?

Output: palpat e the radial or brachial pulse bef ore measuring blood pr essur e

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: 1.1.2 Because aut omat ed de vices ma y not measur e blood pr essur ably if there is pulse irregularity?. ### Response: palpat e the radial or brachial pulse bef ore measuring blood pr essur e.


Instruction: What can palpate the radial fibrillation?

Output: pulse irr egularity (f or example, due t o atrial fibrillation), palpat e the radial or brachial pulse

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can palpate the radial fibrillation?. ### Response: pulse irr egularity (f or example, due t o atrial fibrillation), palpat e the radial or brachial pulse.


Instruction: What is the cause of atrial fibrillation?

Output: pulse irr egularity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of atrial fibrillation?. ### Response: pulse irr egularity.


Instruction: What should providers do if a pulse irregularity is pr esent?

Output: measur e blood pr essur e manually using dir ect auscultation o ver the brachial ar tery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should providers do if a pulse irregularity is pr esent?. ### Response: measur e blood pr essur e manually using dir ect auscultation o ver the brachial ar tery.


Instruction: How should providers measure blood?

Output: properly v alidat ed, maintained

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How should providers measure blood?. ### Response: properly v alidat ed, maintained.


Instruction: What must hcare providers ensur e that de vices f or measuring blood pressur e are properly validat ed, maintained and r egularly?

Output: adequat e initial training and periodic r eview of t heir performance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What must hcare providers ensur e that de vices f or measuring blood pressur e are properly validat ed, maintained and r egularly?. ### Response: adequat e initial training and periodic r eview of t heir performance.


Instruction: What is t he British and Irish Hyper tension Society's writ?

Output: a list of v alidat ed blood pr essur e Hyper tension in adult s: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is t he British and Irish Hyper tension Society's writ?. ### Response: a list of v alidat ed blood pr essur e Hyper tension in adult s: diagnosis and management.


Instruction: What does the British and Irish Hyper tension Society's w ebsite contain?

Output: a list of v alidat ed blood pr essur e Hyper tension in adult s: diagnosis and management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the British and Irish Hyper tension Society's w ebsite contain?. ### Response: a list of v alidat ed blood pr essur e Hyper tension in adult s: diagnosis and management.


Instruction: What is the name of the v alidat ed blood pr essur e?

Output: Irish Hyper tension Society

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the v alidat ed blood pr essur e?. ### Response: Irish Hyper tension Society.


Instruction: What does Notice of right s stand for?

Output: All right s reserved

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Notice of right s stand for?. ### Response: All right s reserved.


Instruction: When was the last updat ed?

Output: 18 Mar ch 2022

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last updat ed?. ### Response: 18 Mar ch 2022.


Instruction: What are reviewers required to complete and submit?

Output: Questionnaire

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are reviewers required to complete and submit?. ### Response: Questionnaire.


Instruction: What is considered significant if the person receives $10 000 or more during any 12-month period?

Output: A relationship

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered significant if the person receives $10 000 or more during any 12-month period?. ### Response: A relationship.


Instruction: If the person owns 5% or more of the voting rights, what is considered to be significant?

Output: stock or share of the entity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: If the person owns 5% or more of the voting rights, what is considered to be significant?. ### Response: stock or share of the entity.


Instruction: How much of the voting stock or share of the entity does the person own?

Output: 5% or more

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the voting stock or share of the entity does the person own?. ### Response: 5% or more.


Instruction: What is a relationship considered to be if it is less than “significant” under the preceding definition?

Output: modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a relationship considered to be if it is less than “significant” under the preceding definition?. ### Response: modest.


Instruction: What is less than “significant” under the preceding definition?

Output: A relationship is considered to be “modest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less than “significant” under the preceding definition?. ### Response: A relationship is considered to be “modest.


Instruction: When was this document downloaded?

Output: April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this document downloaded?. ### Response: April 28, 2023.


Instruction: What is the primary goal of testing among patients with new onset of symptoms suggesting SIHD?

Output: to diagnose orexclude obstructive CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary goal of testing among patients with new onset of symptoms suggesting SIHD?. ### Response: to diagnose orexclude obstructive CAD.


Instruction: What can provide additional information about long-term risk?

Output: various modalities

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can provide additional information about long-term risk?. ### Response: various modalities.


Instruction: What may influence the selection of an initial test?

Output: prognostic ability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may influence the selection of an initial test?. ### Response: prognostic ability.


Instruction: Exercise capacity remains one of the strongest indicators of long-term risk (including death) for what type of CAD?

Output: suspected and known CAD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Exercise capacity remains one of the strongest indicators of long-term risk (including death) for what type of CAD?. ### Response: suspected and known CAD.


Instruction: What providescremental diagnostic and prognostic information?

Output: treadmill exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What providescremental diagnostic and prognostic information?. ### Response: treadmill exercise.


Instruction: What is preferable to perform exercise stress if the patient is able to achieve a maximal workload?

Output: information derived from treadmill exercise (eg,Duke treadmill score126,127 and heart rate recovery) providesincremental diagnostic and prognostic information

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is preferable to perform exercise stress if the patient is able to achieve a maximal workload?. ### Response: information derived from treadmill exercise (eg,Duke treadmill score126,127 and heart rate recovery) providesincremental diagnostic and prognostic information.


Instruction: When was the exercise-e374 Circulation?

Output: December 18/25, 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the exercise-e374 Circulation?. ### Response: December 18/25, 2012.


Instruction: What type of infarction is managed by the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

Output: ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of infarction is managed by the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: ST-elevation myocardial infarction.


Instruction: What is the name of the group that authored the executive summary of the management of ST-elevation myocardial infartion?

Output: American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that authored the executive summary of the management of ST-elevation myocardial infartion?. ### Response: American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.


Instruction: What is angina?

Output: unstable

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is angina?. ### Response: unstable.


Instruction: What is a primary preven-tion with aspirin?

Output: risk factor reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a primary preven-tion with aspirin?. ### Response: risk factor reduction.


Instruction: How many cases of sus-pected acute myocardial infarction were included in the ISIS-1 trial?

Output: 16 027

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many cases of sus-pected acute myocardial infarction were included in the ISIS-1 trial?. ### Response: 16 027.


Instruction: When was the first international study of infarct survival collaborative group conducted?

Output: 1986

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the first international study of infarct survival collaborative group conducted?. ### Response: 1986.


Instruction: What is the name of the TIMI Study Group?

Output: Thrombolysis in Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the TIMI Study Group?. ### Response: Thrombolysis in Myocardial Infarction.


Instruction: What is a term for the Thrombolysis in Myocardial Infarction trial?

Output: TIMI Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a term for the Thrombolysis in Myocardial Infarction trial?. ### Response: TIMI Study Group.


Instruction: What is COMMIT?

Output: ClOpidogrel and Metoprolol in Myocardial Infarction Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is COMMIT?. ### Response: ClOpidogrel and Metoprolol in Myocardial Infarction Trial.


Instruction: How many patients with acute myocardial infarction were enrolled in a randomised placebo-controlled trial?

Output: 45,852

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients with acute myocardial infarction were enrolled in a randomised placebo-controlled trial?. ### Response: 45,852.


Instruction: What is the name of the trial that enrolled 45,852 patients?

Output: COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that enrolled 45,852 patients?. ### Response: COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial.


Instruction: When was the Lancet 366:1622-1632?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Lancet 366:1622-1632?. ### Response: 2005.


Instruction: What is the name of the randomised placebo-controlled trial?

Output: COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) Collaborative Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised placebo-controlled trial?. ### Response: COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) Collaborative Group.


Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines write a report on?

Output: management of ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology/American Heart Association Task Force on Practice Guidelines write a report on?. ### Response: management of ST-elevation myocardial infarction.


Instruction: What was the name of the Task Force to Revise the 2002 Guidelines for The Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction?

Output: Writing Committee

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the Task Force to Revise the 2002 Guidelines for The Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction?. ### Response: Writing Committee.


Instruction: What is the name of the non-ST-Elevation myocardial infarction?

Output: unstable angina

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the non-ST-Elevation myocardial infarction?. ### Response: unstable angina.


Instruction: When was the Circulation.116:e148–e304?

Output: 2007

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Circulation.116:e148–e304?. ### Response: 2007.


Instruction: What is one of the reasons for the use of beta-blockers in COPD?

Output: chronic obstructive pulmonary disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the reasons for the use of beta-blockers in COPD?. ### Response: chronic obstructive pulmonary disease.


Instruction: What is the name of the trial that evaluated recurrent ischaemia in patients treated with nifedipine or metoprolol?

Output: Holland Interuniversity Nifedipine/Metoprolol Trial (HINT) Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that evaluated recurrent ischaemia in patients treated with nifedipine or metoprolol?. ### Response: Holland Interuniversity Nifedipine/Metoprolol Trial (HINT) Research Group.


Instruction: When was the HINT trial conducted?

Output: 1986

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the HINT trial conducted?. ### Response: 1986.


Instruction: What drug was used to treat unstable angina?

Output: nifedipine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug was used to treat unstable angina?. ### Response: nifedipine.


Instruction: What is the Danish Multicenter Study Group on Verapamil in Myocardial Infarction known as?

Output: DA VIT I and II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Danish Multicenter Study Group on Verapamil in Myocardial Infarction known as?. ### Response: DA VIT I and II.


Instruction: When was the Eur Heart J.4:516–528 published?

Output: 2005

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Eur Heart J.4:516–528 published?. ### Response: 2005.


Instruction: What is DA VIT?

Output: Danish Studies on Verapamil in Myocardial Infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is DA VIT?. ### Response: Danish Studies on Verapamil in Myocardial Infarction.


Instruction: What are the Danish Studies on Verapamil in Myocardial Infarction (DA VIT I and II) called?

Output: Multicenter Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the Danish Studies on Verapamil in Myocardial Infarction (DA VIT I and II) called?. ### Response: Multicenter Study Group.


Instruction: Drugs. 1991;42(suppl 2):43–53.

Output: Drugs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Drugs. 1991;42(suppl 2):43–53.. ### Response: Drugs.


Instruction: Hansen JF, Tingsted L, Rasmussen V, Madsen JK, Jespersen CM, what is the name of the study?

Output: TIMI Study Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Hansen JF, Tingsted L, Rasmussen V, Madsen JK, Jespersen CM, what is the name of the study?. ### Response: TIMI Study Group.


Instruction: What is used in warfarin-related intracranial hemorrhage?

Output: factor IX complex

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is used in warfarin-related intracranial hemorrhage?. ### Response: factor IX complex.


Instruction: What is the name of the study that investigated the effectiveness and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists?

Output: phase IIIb study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the effectiveness and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists?. ### Response: phase IIIb study.


Instruction: What is the name of the phase IIIb study in patients on vitamin K antagonistspresenting with major bleeding?

Output: Efficacy and safety of a 4-factor prothrombin complex concentrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the phase IIIb study in patients on vitamin K antagonistspresenting with major bleeding?. ### Response: Efficacy and safety of a 4-factor prothrombin complex concentrate.


Instruction: When did a randomised trial of fresh frozen plasma versus prothrombin complex concentrate take place?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did a randomised trial of fresh frozen plasma versus prothrombin complex concentrate take place?. ### Response: 2016.


Instruction: What is the name of the randomised trial of ovitamin K antagonists?

Output: INCH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomised trial of ovitamin K antagonists?. ### Response: INCH.


Instruction: What is a 3-Factor versus 4-factor prothrombin complex concentrate for warfarin rev ersalin severe bleeding?

Output: a multicenter, retrospective, propensity-matched pilot study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 3-Factor versus 4-factor prothrombin complex concentrate for warfarin rev ersalin severe bleeding?. ### Response: a multicenter, retrospective, propensity-matched pilot study.


Instruction: What is the name of the study that examined the cost-effectiveness of prothrombin complex concentrate compared with fresh frozen plasma in emergen cywarfarin reversal in the United Kingdom?

Output: Clin Ther

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the cost-effectiveness of prothrombin complex concentrate compared with fresh frozen plasma in emergen cywarfarin reversal in the United Kingdom?. ### Response: Clin Ther.


Instruction: What is the name of the study that investigated prothrombin complex concentrate administration?

Output: randomised trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated prothrombin complex concentrate administration?. ### Response: randomised trial.


Instruction: What is rivaroxaban associated with?

Output: major bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is rivaroxaban associated with?. ### Response: major bleeding.


Instruction: What is the SAMURAI-NVAF stu dy.J Neurol Sci. 2017;375:150-157.190?

Output: Prothrombin complex concentrate administration for bleeding associated with non-vitamin K antagonist oral anticoagulants

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the SAMURAI-NVAF stu dy.J Neurol Sci. 2017;375:150-157.190?. ### Response: Prothrombin complex concentrate administration for bleeding associated with non-vitamin K antagonist oral anticoagulants.


Instruction: What is RETRACE II?

Output: German-Wide Multicenter Analysis of Oral Anticoagulation-Associated IntracerebralHemorrhage II

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is RETRACE II?. ### Response: German-Wide Multicenter Analysis of Oral Anticoagulation-Associated IntracerebralHemorrhage II.


Instruction: What is an antidote for intracranial bleeding in pat ientstaking direct factor Xa inhibitors?

Output: 4-factor prothrombin complex concentrate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an antidote for intracranial bleeding in pat ientstaking direct factor Xa inhibitors?. ### Response: 4-factor prothrombin complex concentrate.


Instruction: What is the association between prothrombin complex concentrate administration and hematoma enlargement?

Output: non-vitamin K antagoni storal anticoagulant-related intracerebral hemorrhage

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between prothrombin complex concentrate administration and hematoma enlargement?. ### Response: non-vitamin K antagoni storal anticoagulant-related intracerebral hemorrhage.


Instruction: What is bleeding in pat ientstaking direct factor Xa inhibitors?

Output: intracranial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is bleeding in pat ientstaking direct factor Xa inhibitors?. ### Response: intracranial.


Instruction: What is the name of the prosp ectivecohort study of Prothrombin complex concentrate?

Output: phase IIIb study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the prosp ectivecohort study of Prothrombin complex concentrate?. ### Response: phase IIIb study.


Instruction: What does Dentali F, Marchesi C, Giorgi Pierfranceschi M, et al. recommend for rapid anticoagulation reversal of vitami nKantagonists?

Output: Safety of prothrombin complex concentrates

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Dentali F, Marchesi C, Giorgi Pierfranceschi M, et al. recommend for rapid anticoagulation reversal of vitami nKantagonists?. ### Response: Safety of prothrombin complex concentrates.


Instruction: What is a meta-analysis of prothrombin complex concentrates for?

Output: rapid anticoagulation reversal of vitami nKantagonists

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a meta-analysis of prothrombin complex concentrates for?. ### Response: rapid anticoagulation reversal of vitami nKantagonists.


Instruction: When was Thromb Haemost 106(3):429-438.194 published?

Output: 2011

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Thromb Haemost 106(3):429-438.194 published?. ### Response: 2011.


Instruction: What type of bleeding is associated with factor Xa inhib itors?

Output: acute major

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of bleeding is associated with factor Xa inhib itors?. ### Response: acute major.


Instruction: What year did N Engl J Med issue 375(12):1131-1141?

Output: 2016

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year did N Engl J Med issue 375(12):1131-1141?. ### Response: 2016.


Instruction: What is the cause of supra-ventricular tachycardia in pediatrics influenced by?

Output: age, gender or ethnic-ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the cause of supra-ventricular tachycardia in pediatrics influenced by?. ### Response: age, gender or ethnic-ity.


Instruction: What is atrioventricular conduc-tion properties of patients with Wolff-Parkinson-White syndrome?

Output: Gender

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atrioventricular conduc-tion properties of patients with Wolff-Parkinson-White syndrome?. ### Response: Gender.


Instruction: When did J Electrocardiol. 2001;34:295–301?

Output: 2001

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did J Electrocardiol. 2001;34:295–301?. ### Response: 2001.


Instruction: How is the mechanism of supra-ventricular tachycardia in pediatrics influenced?

Output: age, gender or ethnic-ity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is the mechanism of supra-ventricular tachycardia in pediatrics influenced?. ### Response: age, gender or ethnic-ity.


Instruction: What is the name of the study of 748 patients after high frequency catheter ablation?

Output: Med Klin (Munich).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study of 748 patients after high frequency catheter ablation?. ### Response: Med Klin (Munich)..


Instruction: How many patients were studied after high frequency catheter ablation?

Output: 748

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients were studied after high frequency catheter ablation?. ### Response: 748.


Instruction: What is the name of the study that studied 748 patients?

Output: Med Klin (Munich).

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that studied 748 patients?. ### Response: Med Klin (Munich)..


Instruction: When was the study conducted?

Output: 1997

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the study conducted?. ### Response: 1997.


Instruction: What is Wolff-Parkinson-White syndrome and atrioventricular nodal re-entry tachycardia in a Swedish population?

Output: consequences on health-related quality of life

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Wolff-Parkinson-White syndrome and atrioventricular nodal re-entry tachycardia in a Swedish population?. ### Response: consequences on health-related quality of life.


Instruction: What are the consequences on health-related quality of life?

Output: Wolff-Parkinson-White syndrome and atrioventricular nodal re-entry tachycardia in a Swedish population

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the consequences on health-related quality of life?. ### Response: Wolff-Parkinson-White syndrome and atrioventricular nodal re-entry tachycardia in a Swedish population.


Instruction: When was Wolff-Parkinson-White syndrome diagnosed?

Output: childhood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Wolff-Parkinson-White syndrome diagnosed?. ### Response: childhood.


Instruction: What is the potential for misdiagnosis of unrecognized paroxysmal supraventricular tachycardia?

Output: panic disorder

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the potential for misdiagnosis of unrecognized paroxysmal supraventricular tachycardia?. ### Response: panic disorder.


Instruction: Leong-Poi H, Mangat I, et al. Influence of ventriculoatrial tim-ing on hemodynamics and symptoms during supraventricular tachycardia.

Output: 62

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Leong-Poi H, Mangat I, et al. Influence of ventriculoatrial tim-ing on hemodynamics and symptoms during supraventricular tachycardia.. ### Response: 62.


Instruction: J Cardiovasc Electrophysiol. 2009;20:176–81.

Output: 63

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: J Cardiovasc Electrophysiol. 2009;20:176–81.. ### Response: 63.


Instruction: Abe H, Nagatomo T, Kobayashi H, and al. Neurohumoral and hemodynamic mechanisms of diuresis during what?

Output: atrioventricular nodal reentrant tachycar -dia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Abe H, Nagatomo T, Kobayashi H, and al. Neurohumoral and hemodynamic mechanisms of diuresis during what?. ### Response: atrioventricular nodal reentrant tachycar -dia.


Instruction: What is tachycar-dia?

Output: atrioventricular nodal reentrant

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is tachycar-dia?. ### Response: atrioventricular nodal reentrant.


Instruction: When did Pacing Clin Electrophysiol. 1997:20:2783–8.

Output: 64

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Pacing Clin Electrophysiol. 1997:20:2783–8.. ### Response: 64.


Instruction: What is the lack of prognostic value of syncope in patients with Wolff-Parkinson-White syndrome?

Output: 64

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the lack of prognostic value of syncope in patients with Wolff-Parkinson-White syndrome?. ### Response: 64.


Instruction: What did Drago F, Turchetta A, Calzolari A, et al. do?

Output: Reciprocating supraventricular tachycardia in children

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Drago F, Turchetta A, Calzolari A, et al. do?. ### Response: Reciprocating supraventricular tachycardia in children.


Instruction: What is a major factor related to propen-sity to syncope during exercise?

Output: low rate at rest

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a major factor related to propen-sity to syncope during exercise?. ### Response: low rate at rest.


Instruction: What is low rate at rest related to?

Output: propen-sity to syncope during exercise

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low rate at rest related to?. ### Response: propen-sity to syncope during exercise.


Instruction: When did Am Heart J issue 132:280-5?

Output: 1996

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Am Heart J issue 132:280-5?. ### Response: 1996.


Instruction: What is the name of the clinical presentation and results of radiofrequency catheter abla-tion therapy?

Output: Electrophysiologic characteris-tics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the clinical presentation and results of radiofrequency catheter abla-tion therapy?. ### Response: Electrophysiologic characteris-tics.


Instruction: When was the Coron Artery Dis. 9:359–63 published?

Output: 1998

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Coron Artery Dis. 9:359–63 published?. ### Response: 1998.


Instruction: What is atrioventricular nodal reentrant tachycardia?

Output: Electrophysiologic characteris-tics and results of radiofrequency catheter ablation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is atrioventricular nodal reentrant tachycardia?. ### Response: Electrophysiologic characteris-tics and results of radiofrequency catheter ablation.


Instruction: Electrocardiol. 2007;40:208–13.

Output: 68

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Electrocardiol. 2007;40:208–13.. ### Response: 68.


Instruction: Leitch JW, Klein GJ, Yee R, et al. Syncope associated with supraventricu-lar tachycardia: an expression of what?

Output: tachycardia rate or vasomotor response

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Leitch JW, Klein GJ, Yee R, et al. Syncope associated with supraventricu-lar tachycardia: an expression of what?. ### Response: tachycardia rate or vasomotor response.


Instruction: Circulation. 1992;85:1064–71.

Output: 69

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 1992;85:1064–71.. ### Response: 69.


Instruction: What was the amean follow-up of ONTARGET278?

Output: 39 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the amean follow-up of ONTARGET278?. ### Response: 39 months.


Instruction: What was there no bene fit in all-cause mortality?

Output: Combining data for patients who have both CKD anddiabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was there no bene fit in all-cause mortality?. ### Response: Combining data for patients who have both CKD anddiabetes.


Instruction: How many patients had both CKD and diabetes?

Output: 280

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients had both CKD and diabetes?. ### Response: 280.


Instruction: Powers and al 2019 Guidelines for Management of AIS e3936.6. Antithrombotic Treatment6.6.1. Noncardioembolic Stroke COR LOE New, Revised, or Unchanged What is the use of antiplatelet agents rather than oral anticoagulation recommended for?

Output: reduce the risk of recurrent stroke and other cardiovascular events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Powers and al 2019 Guidelines for Management of AIS e3936.6. Antithrombotic Treatment6.6.1. Noncardioembolic Stroke COR LOE New, Revised, or Unchanged What is the use of antiplatelet agents rather than oral anticoagulation recommended for?. ### Response: reduce the risk of recurrent stroke and other cardiovascular events.


Instruction: What year was the I ARecommendation reworded for clarity?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What year was the I ARecommendation reworded for clarity?. ### Response: 2014.


Instruction: COR and LOE remain unchanged.

Output: 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: COR and LOE remain unchanged.. ### Response: 2.


Instruction: What should be selected for early secondary prevention in patients with noncardioembolic AIS?

Output: antiplatelet agent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be selected for early secondary prevention in patients with noncardioembolic AIS?. ### Response: antiplatelet agent.


Instruction: What should the selection of an antiplatelet agent be individualized on?

Output: patient risk factor profiles, cost, tolerance, relative known efficacy of the agents, and other clinical characteristics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should the selection of an antiplatelet agent be individualized on?. ### Response: patient risk factor profiles, cost, tolerance, relative known efficacy of the agents, and other clinical characteristics.


Instruction: What should patient risk factor profiles, cost, tolerance, relative known efficacy of the agents, and other clinical characteristics be?

Output: individualized

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patient risk factor profiles, cost, tolerance, relative known efficacy of the agents, and other clinical characteristics be?. ### Response: individualized.


Instruction: I C-EORecommendation reworded for clarity from what year?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: I C-EORecommendation reworded for clarity from what year?. ### Response: 2014.


Instruction: What is the COR unchanged?

Output: LOE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the COR unchanged?. ### Response: LOE.


Instruction: What was the LOE amended to conform with?

Output: ACC/AHA 2015 Recommendation Classification System

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the LOE amended to conform with?. ### Response: ACC/AHA 2015 Recommendation Classification System.


Instruction: Where is the original wording of Table XCV?

Output: online Data Supplement 1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the original wording of Table XCV?. ### Response: online Data Supplement 1.


Instruction: What is not well established in secondary stroke prevention?

Output: switching to an alternative antiplatelet agent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not well established in secondary stroke prevention?. ### Response: switching to an alternative antiplatelet agent.


Instruction: When was the IIb B-RRecommendation revised?

Output: 2014

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the IIb B-RRecommendation revised?. ### Response: 2014.


Instruction: What is the therapeutic benefit of aspirin in noncardioembolic ischemic stroke?

Output: similar across a wide range of doses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the therapeutic benefit of aspirin in noncardioembolic ischemic stroke?. ### Response: similar across a wide range of doses.


Instruction: What does the hemorrhagic risk increase with higher doses?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the hemorrhagic risk increase with higher doses?. ### Response: aspirin.


Instruction: What is not well established in patients taking aspirin at the time of an incident stroke?

Output: the benefit of switching to an alternative antiplatelet agent or combination therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not well established in patients taking aspirin at the time of an incident stroke?. ### Response: the benefit of switching to an alternative antiplatelet agent or combination therapy.


Instruction: The SPS3 RCT found no benefit from what?

Output: adding clopidogrel to aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The SPS3 RCT found no benefit from what?. ### Response: adding clopidogrel to aspirin.


Instruction: What did the SPS3 trial find no benefit from adding clopidogrel to aspirin compared with placebo?

Output: patients with a recent small vessel, lacunar stroke taking aspirin at the time of their index event

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the SPS3 trial find no benefit from adding clopidogrel to aspirin compared with placebo?. ### Response: patients with a recent small vessel, lacunar stroke taking aspirin at the time of their index event.


Instruction: What was the median time from the qualifying event to enrollment in the trial?

Output: >40 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median time from the qualifying event to enrollment in the trial?. ### Response: >40 days.


Instruction: How long did it take for patients with a recent small vessel, lacunar stroke to enroll in the study?

Output: >40 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for patients with a recent small vessel, lacunar stroke to enroll in the study?. ### Response: >40 days.


Instruction: How long was the qualifying event to enrollment in the SPS3 trial?

Output: >40 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long was the qualifying event to enrollment in the SPS3 trial?. ### Response: >40 days.


Instruction: What may have underestimated benefit in the early poststroke period?

Output: the median time from the qualifying event to enrollment in the SPS3 trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may have underestimated benefit in the early poststroke period?. ### Response: the median time from the qualifying event to enrollment in the SPS3 trial.


Instruction: How many studies did a recent meta-analysis of 5 studies include?

Output: 3 RCTs and 2 observational registries

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies did a recent meta-analysis of 5 studies include?. ### Response: 3 RCTs and 2 observational registries.


Instruction: What was found to decrease the risk of major cardiovascular events and recurrent stroke in patients switching to an alternative antiplatelet agent?

Output: aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was found to decrease the risk of major cardiovascular events and recurrent stroke in patients switching to an alternative antiplatelet agent?. ### Response: aspirin.


Instruction: What was included in the analysis of data from aspirin failure subgroups?

Output: CHANCE trial of dual antiplatelet therapy in patients with minor stroke or TIA and the SOCRATES trial of aspirin versus ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was included in the analysis of data from aspirin failure subgroups?. ### Response: CHANCE trial of dual antiplatelet therapy in patients with minor stroke or TIA and the SOCRATES trial of aspirin versus ticagrelor.


Instruction: What were the subgroups in the CHANCE trial of?

Output: aspirin failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the subgroups in the CHANCE trial of?. ### Response: aspirin failure.


Instruction: What was the SOCRATES trial of aspirin versus?

Output: ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the SOCRATES trial of aspirin versus?. ### Response: ticagrelor.


Instruction: Data from registries are susceptible to unmeasured confounders and what else?

Output: bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Data from registries are susceptible to unmeasured confounders and what else?. ### Response: bias.


Instruction: Bozkurt et alDecember 6, 2016 Circulation. 2016;134:e535–e578 What is recommended for individuals with 140 mm Hg SBP or 90 mm hg diastolic BP?

Output: individuals with ≥140 mm Hg SBP or 90 mm Hg diastolic BP are recommended

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bozkurt et alDecember 6, 2016 Circulation. 2016;134:e535–e578 What is recommended for individuals with 140 mm Hg SBP or 90 mm hg diastolic BP?. ### Response: individuals with ≥140 mm Hg SBP or 90 mm Hg diastolic BP are recommended.


Instruction: What can be useful for BP control and to reverse mild volume overload?

Output: Thiazide or thiazide-like diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be useful for BP control and to reverse mild volume overload?. ### Response: Thiazide or thiazide-like diuretics.


Instruction: What are the preferred agents for treatment of congestion in symp-tomatic patients with HF?

Output: Loop diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the preferred agents for treatment of congestion in symp-tomatic patients with HF?. ### Response: Loop diuretics.


Instruction: What is less effective than thiazide or thiacetic-like diuretics in low-ering BP?

Output: Loop diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is less effective than thiazide or thiacetic-like diuretics in low-ering BP?. ### Response: Loop diuretics.


Instruction: What are diuretics in low-ering BP classified as?

Output: Class IIa

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are diuretics in low-ering BP classified as?. ### Response: Class IIa.


Instruction: What may be benefi-cial in non-black patients with HFrEF and hyper-tension?

Output: hydralazine/isosorbide dini-trate to the background treatment with an ACE inhibitor or ARB and a β -blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be benefi-cial in non-black patients with HFrEF and hyper-tension?. ### Response: hydralazine/isosorbide dini-trate to the background treatment with an ACE inhibitor or ARB and a β -blocker.


Instruction: What class of drugs are to be avoided in patients with HF and hyper-tension?

Output: α-Adrenergic blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What class of drugs are to be avoided in patients with HF and hyper-tension?. ### Response: α-Adrenergic blockers.


Instruction: What is a class III: Harm; Level of Evidence C?

Output: moxonidine

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a class III: Harm; Level of Evidence C?. ### Response: moxonidine.


Instruction: When HFrEF Is Manifest, What is Higher Bp Associated With?

Output: Better prognosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When HFrEF Is Manifest, What is Higher Bp Associated With?. ### Response: Better prognosis.


Instruction: What is an epidemiological paradox in the HF-hypertension relationship?

Output: significantly increased mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an epidemiological paradox in the HF-hypertension relationship?. ### Response: significantly increased mortality.


Instruction: What is associated with a worse prognosis once advanced HFrEF is manifest?

Output: lower BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with a worse prognosis once advanced HFrEF is manifest?. ### Response: lower BP.


Instruction: What may be a marker of the abil-ity of the ventricle to generate a SBP or better cardiac output?

Output: higher SBP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be a marker of the abil-ity of the ventricle to generate a SBP or better cardiac output?. ### Response: higher SBP.


Instruction: What is attributable to a loss of myocardial contractility in advanced HF?

Output: higher BP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is attributable to a loss of myocardial contractility in advanced HF?. ### Response: higher BP.


Instruction: What is a SBP or better cardiac output?

Output: ≤110 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a SBP or better cardiac output?. ### Response: ≤110 mm Hg.


Instruction: The BP ranges demonstrated to have an association with mortality in retrospective analyses were not defined or validated as what?

Output: targets

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The BP ranges demonstrated to have an association with mortality in retrospective analyses were not defined or validated as what?. ### Response: targets.


Instruction: What was accepted as a target for BP control in patients with HF?

Output: Thiazide or thiazide-like diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was accepted as a target for BP control in patients with HF?. ### Response: Thiazide or thiazide-like diuretics.


Instruction: In the Digitalis Investigation Group trial database, what was significantly higher for patients in the lowest SBP group?

Output: mor-tality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In the Digitalis Investigation Group trial database, what was significantly higher for patients in the lowest SBP group?. ### Response: mor-tality.


Instruction: What was the SBP range of patients in the Valsartan Heart Failure Trial?

Output: ≤110 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the SBP range of patients in the Valsartan Heart Failure Trial?. ### Response: ≤110 mm Hg.


Instruction: What is the 95% confidence interval between 1.25 and 2.17?

Output: CI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 95% confidence interval between 1.25 and 2.17?. ### Response: CI.


Instruction: Patients in the lowest quartile of SBP had more severe HF and what?

Output: a significantly increased mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients in the lowest quartile of SBP had more severe HF and what?. ### Response: a significantly increased mortality.


Instruction: What was the HR of patients in the upper 3 quartiles of baseline SBP?

Output: 1.65

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the HR of patients in the upper 3 quartiles of baseline SBP?. ### Response: 1.65.


Instruction: What is the mean SBP of patients with acute HF?

Output: 130 to 139 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the mean SBP of patients with acute HF?. ### Response: 130 to 139 mm Hg.


Instruction: What type of HF is seen in patients with acute decompensated HF?

Output: severe

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of HF is seen in patients with acute decompensated HF?. ### Response: severe.


Instruction: What is the abbreviation for the American College of Chest Physicians?

Output: 2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the abbreviation for the American College of Chest Physicians?. ### Response: 2012.


Instruction: How many h after LMWH administration?

Output: 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many h after LMWH administration?. ### Response: 4.


Instruction: What was Kimberly Henricks's profession?

Output: American College of Chest Physicians

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was Kimberly Henricks's profession?. ### Response: American College of Chest Physicians.


Instruction: What group of people are involved in the decision-making process?

Output: physicians, other clinicians, and decision-makers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group of people are involved in the decision-making process?. ### Response: physicians, other clinicians, and decision-makers.


Instruction: What is the name of the book that was published by guest on 21 April 2023?

Output: advances024893cg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that was published by guest on 21 April 2023?. ### Response: advances024893cg.


Instruction: What is the name of the book that discusses the diagnosis of heart failure?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that discusses the diagnosis of heart failure?. ### Response: Chronic Heart Failure.


Instruction: What does NICE 2018 stand for?

Output: Chronic Heart Failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does NICE 2018 stand for?. ### Response: Chronic Heart Failure.


Instruction: How many studies are there?

Output: Three studies (n= 826

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies are there?. ### Response: Three studies (n= 826.


Instruction: What percentage of the population is PPV?

Output: Positive Predictive Value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of the population is PPV?. ### Response: Positive Predictive Value.


Instruction: What percentage is NPV)?

Output: Negative Predictive Value

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage is NPV)?. ### Response: Negative Predictive Value.


Instruction: Why is NT-pro BNP 400 pg/mL VERY LOW?

Output: serious inconsistency, very serious imprecision

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is NT-pro BNP 400 pg/mL VERY LOW?. ### Response: serious inconsistency, very serious imprecision.


Instruction: Inconsistency, very serious imprecision What is Pooledf: 79 (42 - 96)?

Output: LOWb

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Inconsistency, very serious imprecision What is Pooledf: 79 (42 - 96)?. ### Response: LOWb.


Instruction: How many pg/mL 1 200 is NT-pro BNP 2000?

Output: 400

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pg/mL 1 200 is NT-pro BNP 2000?. ### Response: 400.


Instruction: How many NT-pro BNP 2000 pg/mL 1 200 HIGH 2 (0 - 10) 100 (97 - 100) 100 71 0.86 (0.80 - 0.92) [Threshold data not accurately reported] 1 384 VERY LOWa,c due to serious risk of bias, serious indirectness?

Output: 100 71 0.86 (0.80 – 0.92)  [Threshold data not accurately reported]  1 384 VERY LOWa,c due to serious risk of bias, serious indirectness    - - 0.74

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many NT-pro BNP 2000 pg/mL 1 200 HIGH 2 (0 - 10) 100 (97 - 100) 100 71 0.86 (0.80 - 0.92) [Threshold data not accurately reported] 1 384 VERY LOWa,c due to serious risk of bias, serious indirectness?. ### Response: 100 71 0.86 (0.80 – 0.92)  [Threshold data not accurately reported]  1 384 VERY LOWa,c due to serious risk of bias, serious indirectness    - - 0.74.


Instruction: The GC identified test sensitivity as the primary measure in guiding what?

Output: decision making

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The GC identified test sensitivity as the primary measure in guiding what?. ### Response: decision making.


Instruction: The rule in thresholds of how many ng/mL is very high?

Output: 400

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: The rule in thresholds of how many ng/mL is very high?. ### Response: 400.


Instruction: What was the sensitivity threshold to recomend a test?

Output: 95%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the sensitivity threshold to recomend a test?. ### Response: 95%.


Instruction: What was assessed using the QUADAS -2?

Output: Risk of bias

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was assessed using the QUADAS -2?. ### Response: Risk of bias.


Instruction: How was risk of bias assessed?

Output: using the QUADAS -2 checklist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How was risk of bias assessed?. ### Response: using the QUADAS -2 checklist.


Instruction: What was the risk of bias assessed using?

Output: QUADAS -2 checklist

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the risk of bias assessed using?. ### Response: QUADAS -2 checklist.