The principles of replacement, reduction and refinement in the area of animal experimentation laid down in the Directive 2010/63/EU of the European Parliament and the Council [16] should be observed.
Ba cheart na prionsabail a urramú maidir le hionadú, laghdú agus feabhsú i dturgnaimh ar ainmhithe a leagtar síos i dTreoir 2010/63/AE ó Pharlaimint na hEorpa agus ón gComhairle [16].