qnli question: What philosophy combined with Descartes to push quantum activity in the 20th century? sentence: With the acquiescence of Cartesian mechanical philosophy to the "brute fact" of action at a distance, and at length, its successful reification by force fields and ever more sophisticated geometric structure, the anachronism of empty space widened until "a seething ferment" of quantum activity in the 20th century filled the vacuum with a virtual pleroma.