qnli question: When will organomagnesium halide formation fail? sentence: Among important applications is the Frankland-Duppa Reaction in which an oxalate ester(ROCOCOOR) reacts with an alkyl halide R'X, zinc and hydrochloric acid to the α-hydroxycarboxylic esters RR'COHCOOR, the Reformatskii reaction which converts α-halo-esters and aldehydes to β-hydroxy-esters, the Simmons–Smith reaction in which the carbenoid (iodomethyl)zinc iodide reacts with alkene(or alkyne) and converts them to cyclopropane, the Addition reaction of organozinc compounds to carbonyl compounds.