title: fatal error: 'openssl/e_os2.h' file not found in pypy
body: <p>When I Run Command pypy -m pip install cryptography</p>
  
  <p>then I have got below Errors:</p>
  
  <p>cc -arch x86_64 -O2 -fPIC -Wimplicit -I/opt/pypy-5.0.1/include -c build/temp.macosx-10.10-x86_64-2.7/_openssl.c -o build/temp.macosx-10.10-x86_64-2.7/build/temp.macosx-10.10-x86_64-2.7/_openssl.o
      build/temp.macosx-10.10-x86_64-2.7/_openssl.c:423:10: fatal error: 'openssl/e_os2.h' file not found
      #include 
               ^
      1 error generated.
      error: command 'cc' failed with exit status 1</p>
  
  <pre><code>----------------------------------------
  </code></pre>
  
  <p>Command "/usr/local/bin/pypy -u -c "import setuptools, tokenize;<strong>file</strong>='/private/var/folders/_t/8l_tq9210xl4bzlhkspnv8br0000gn/T/pip-build-Gjhf5l/cryptography/setup.py';exec(compile(getattr(tokenize, 'open', open)(<strong>file</strong>).read().replace('\r\n', '\n'), <strong>file</strong>, 'exec'))" install --record /var/folders/_t/8l_tq9210xl4bzlhkspnv8br0000gn/T/pip-6_y8I9-record/install-record.txt --single-version-externally-managed --compile" failed with error code 1 in /private/var/folders/_t/8l_tq9210xl4bzlhkspnv8br0000gn/T/pip-build-Gjhf5l/cryptography/</p>