title: specific Bioconductor packages fail when deployed to shinyapps.io
body: <p>I am trying to deploy a shiny app to shinyapps.io in RStudio and keep getting an error with a Bioconductor package.</p>
  <p>I've tried the following in console before deploying: <code>options(repos = BiocManager::repositories())</code>, <code>options(rsconnect.max.bundle.size=3145728000)</code> and <code>options(timeout=1500)</code></p>
  <p>but I still get this error</p>
  <p><code>Error building image: Error fetching MafH5.gnomAD.v3.1.2.GRCh38 (3.15.0) source. Error downloading package source: HTTP 599: Connection closed</code></p>
  <p>MRE below. This will deploy if I comment out <code>library(&quot;MafH5.gnomAD.v3.1.2.GRCh38&quot;)</code> since GenomeInfoDb works, this tells me the repos for Bioconductor are set correctly, but I can't figure out why MafH5.gnomAD would work locally but fail when deployed.</p>
  <pre><code>library(shiny)
  library(BiocManager)
  library(GenomeInfoDb)
  library(BSgenome)
  #library(&quot;MafDb.gnomAD.r2.1.hs37d5&quot;)
  library(&quot;MafH5.gnomAD.v3.1.2.GRCh38&quot;)
  #library(BSgenome.Hsapiens.UCSC.hg19)
  #library(BSgenome.Hsapiens.UCSC.hg38)
  #mafdb_hg19 &lt;- MafDb.gnomAD.r2.1.hs37d5
  #mafdb_hg38 &lt;- MafH5.gnomAD.v3.1.2.GRCh38
  #hg19 &lt;- BSgenome.Hsapiens.UCSC.hg19
  #hg38 &lt;- BSgenome.Hsapiens.UCSC.hg38
  
  
  ui &lt;- fluidPage(
      # Application title
      titlePanel(&quot;test&quot;),
      )
  server &lt;- function(input, output) {
  }
  # Run the application 
  shinyApp(ui = ui, server = server)
  </code></pre>
  <p>RStudio version = 2022.02.3 Build 492
  and</p>
  <pre><code>sessionInfo()
  R version 4.2.0 (2022-04-22 ucrt)
  Platform: x86_64-w64-mingw32/x64 (64-bit)
  Running under: Windows 10 x64 (build 17134)
  
  Matrix products: default
  
  locale:
  [1] LC_COLLATE=English_United States.1252  LC_CTYPE=English_United States.1252    LC_MONETARY=English_United States.1252
  [4] LC_NUMERIC=C                           LC_TIME=English_United States.1252    
  
  attached base packages:
  [1] stats     graphics  grDevices utils     datasets  methods   base     
  
  loaded via a namespace (and not attached):
  [1] BiocManager_1.30.18 compiler_4.2.0      rsconnect_0.8.26    tools_4.2.0         curl_4.3.2          jsonlite_1.8.0     
  [7] digest_0.6.29       openssl_2.0.2       askpass_1.1   ```
  </code></pre>