title: What is the best/preferred approach to implement Maximum Likelihood Estimation for large data sets in GBs
body: <p>I have a data-set in Gigabytes(GB) and want to estimate the parameters for missing values in that. </p>
  
  <p>There is an algorithm called MLE(Maximum-likelihood Estimation) in machine learning that can be used for it.<br>
  Since R might not work on such a large data-set,so which library will be best to use for it?</p>