title: Biopython Entrez error in Pycharm
body: <p>I am new to using Pycharm. I am trying to access Entrez databases using the Bio.Entrez module in Pycharm and get an error message regardless of which Bio.Entrez function I use:</p>
  
  <pre><code>from Bio import Entrez
  handle = Entrez.einfo()
  
  Traceback (most recent call last):
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/urllib/request.py", line 1318, in do_open
  encode_chunked=req.has_header('Transfer-encoding'))
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/http/client.py", line 1239, in request
  self._send_request(method, url, body, headers, encode_chunked)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/http/client.py", line 1285, in _send_request
  self.endheaders(body, encode_chunked=encode_chunked)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/http/client.py", line 1234, in endheaders
  self._send_output(message_body, encode_chunked=encode_chunked)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/http/client.py", line 1026, in _send_output
  self.send(msg)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/http/client.py", line 964, in send
  self.connect()
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/http/client.py", line 1400, in connect
  server_hostname=server_hostname)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/ssl.py", line 401, in wrap_socket
  _context=self, _session=session)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/ssl.py", line 808, in __init__
  self.do_handshake()
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/ssl.py", line 1061, in do_handshake
  self._sslobj.do_handshake()
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/ssl.py", line 683, in do_handshake
  self._sslobj.do_handshake()
  ssl.SSLError: [SSL: CERTIFICATE_VERIFY_FAILED] certificate verify failed (_ssl.c:749)
  During handling of the above exception, another exception occurred:
  Traceback (most recent call last):
  File "&lt;input&gt;", line 1, in &lt;module&gt;
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/site-packages/Bio/Entrez/__init__.py", line 283, in einfo
  return _open(cgi, variables)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/site-packages/Bio/Entrez/__init__.py", line 524, in _open
  handle = _urlopen(cgi)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/urllib/request.py", line 223, in urlopen
  return opener.open(url, data, timeout)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/urllib/request.py", line 526, in open
  response = self._open(req, data)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/urllib/request.py", line 544, in _open
  '_open', req)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/urllib/request.py", line 504, in _call_chain
  result = func(*args)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/urllib/request.py", line 1361, in https_open
  context=self._context, check_hostname=self._check_hostname)
  File "/Library/Frameworks/Python.framework/Versions/3.6/lib/python3.6/urllib/request.py", line 1320, in do_open
  raise URLError(err)
  urllib.error.URLError: &lt;urlopen error [SSL: CERTIFICATE_VERIFY_FAILED] certificate verify failed (_ssl.c:749)&gt;
  </code></pre>
  
  <p>Strangely, it works in Anaconda Spyder, but I prefer PyCharm and would like to figure this out. </p>