title: Problem after installing VSTO runtime 2010 and .Net framework 4
body: <p>Our entire team installed VS 2010(It has both VSTO runtime 2010 and .net framework 4).After installing that some of our developers are getting the below error (but for majority its working fine) while opening the deployed VSTO application from server developed in framework 3.5 and VSRO runtime 3: </p>
  
  <p><em><strong></em>**<em>*</em>**<em></strong> Exception Text <strong></em>**<em>*</em>****</strong>
  Microsoft.VisualStudio.Tools.Applications.Runtime.CannotCreateCustomizationDomainException: Customization does not have the permissions required to create an application domain. ---> System.Security.SecurityException: Customized functionality in this application will not work because the administrator has listed file://fmrdmwaprd2/CA-INSTALL/Demand/Templates/GeoDSS_Templates_UTT/APAC_RevOpt_OEM_Good_Bad_News/APAC_RevOpt_OEM_Good_Bad_News_UTT.vsto as untrusted. Contact your administrator for further assistance.
     at Microsoft.VisualStudio.Tools.Office.Runtime.RuntimeUtilities.VerifySolutionUri(Uri uri)
     at Microsoft.VisualStudio.Tools.Office.Runtime.DomainCreator.CreateCustomizationDomainInternal(String solutionLocation, String manifestName, String documentName, Boolean showUIDuringDeployment, IntPtr hostServiceProvider, IntPtr&amp; executor)
  The Zone of the assembly that failed was:
  MyComputer</p>