title: Cholmod error 'out of memory' : Merging Seurat Objects
body: <p>I am trying to merge Seurat class objects that contain transcriptome count data (sparse matrix).  I am relatively new to R, so any help/solutions is appreciated. I have added a screenshot of the data I'm working with.</p>
  <pre><code>**General Info:**
  -------------
  
  &gt; memory.size(max = TRUE)
  [1] 2533.94
  R version 4.0.3 (2020-10-10)
  Platform: i386-w64-mingw32/i386 (32-bit)
  Running under: Windows 10 x64 (build 19041)
  
  attached base packages:
  [1] stats     graphics  grDevices utils    
  [5] datasets  methods   base     
  
  other attached packages:
  [1] RSQLite_2.2.3 Seurat_3.2.3
  </code></pre>
  <p>I am not sure if my storage is the issue or if I should split the function in two.</p>
  <pre><code> options(stringsAsFactors = F)
  setwd(&quot;C:/Users/Amara/OneDrive - Virginia Tech/XieLab/ZebraFish_Project/zf_brain-master/data&quot;)
  folders &lt;- list.files(&quot;C:/Users/Amara/OneDrive - Virginia Tech/XieLab/ZebraFish_Project/zf_brain-master/data&quot;)
  library(Seurat)
  library(dplyr)
  zfbrainList = lapply(folders,function(folder){ 
    CreateSeuratObject(counts = Read10X(folder), 
                       project = folder )
  })
  zfbrain.combined &lt;- merge(zfbrainList[[1]], 
                   y = c(zfbrainList[[2]],zfbrainList[[3]],zfbrainList[[4]],zfbrainList[[5]],
                         zfbrainList[[6]],zfbrainList[[7]],zfbrainList[[8]],zfbrainList[[9]],
                         zfbrainList[[10]],zfbrainList[[11]],zfbrainList[[12]],zfbrainList[[13]],
                         zfbrainList[[14]],zfbrainList[[15]]), 
                   add.cell.ids = folders, 
                   project = &quot;zebrafish&quot;)
  </code></pre>
  <p>Error in .cbind2Csp(x, y) :
  Cholmod error 'out of memory' at file ../Core/cholmod_memory.c, line 147</p>
  <p><a href="https://1drv.ms/u/s!AgDgtj_I4R0Dwi8HOJGwHxMXqFgv?e=TQE2c6" rel="nofollow noreferrer">Data folder</a></p>
  <p><img src="https://i.stack.imgur.com/sSXj0.png" alt="zfbrainlist" /></p>