what is thiopurine
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Thiopurine The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis), and organ transplant recipients. Metabolism is catalyzed by S-methyltransferase.
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Thiopurines Thiopurines are a class of drugs that are used to suppress the normal activity of the body's immune system. Examples of thiopurine drugs include azathioprine (Imuran®), mercaptopurine (Purinethol®), and thioguanine (6-TG, Tabloid® or Lanvis®).
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Valeant Pharmaceuticals P. Penicillamine Oral. This medication is used to treat rheumatoid arthritis, Wilson's disease (a condition in which high levels of copper in the body cause damage to the liver, brain, and other organs), and a certain disorder which causes kidney stones (cystinuria).
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- Step 4: Move the positive voltmeter lead to the battery. terminal on the solenoid and the negative voltmeter lead to. the terminal that the starter cable is attached. Turn the key. to the start position and read the voltage. The voltage should. read no more than .3 volts. If the reading is more than .3 volts.
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Mercury (II) thiocyanate Mercury thiocyanate has a few uses in chemical synthesis. It is the precursor to potassium tris(thiocyanato)mercurate(II) (K[Hg(SCN) 3 ]) and caesium tris(thiocyanato)mercurate(II) (Cs[Hg(SCN) 3 ]). The Hg(SCN) 3 − ion can also exist independently and is easily generated from the compounds above, amongst others.
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Pentothal WARNING: MAY BE HABIT FORMING. Pentothal (Thiopental Sodium for Injection, USP) is a thiobarbiturate, the sulfur analogue of sodium pentobarbital. The drug is prepared as a sterile powder and after reconstitution with an appropriate diluent is administered by the intravenous route.
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Thiopurine methyltransferase (TPMT) Phenotype test for TPMT. 1  If someone has little to no detectable TPMT activity, they are at risk of developing severe side effects to thiopurine drugs. 2  Usually the doctor will find an alternative drug treatment. 3  Sometimes the doctor may prescribe a very small dose of the thiopurine.
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Thiopurine methyltransferase (TPMT) A doctor will typically order a TPMT enzyme activity test or genetic test before starting a person on thiopurine drug treatment. Occasionally, a TPMT genotype test may be ordered when a person treated with a thiopurine drug experiences side effects, such as a decreased WBC count.henotype test for TPMT. 1  If someone has little to no detectable TPMT activity, they are at risk of developing severe side effects to thiopurine drugs. 2  Usually the doctor will find an alternative drug treatment.
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Thiamine (Redirected from Thiamine mononitrate) Thiamine, also known as thiamin or vitamin B1, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat and prevent thiamine deficiency and disorders that result from it, including beriberi, Korsakoff's syndrome, and Korsakoff's psychosis. Other uses include maple syrup urine disease and Leigh's disease. It is taken by mouth or by injection.
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Beriberi (Thiamine Deficiency) Thiamine deficiency, or beriberi, refers to the lack of thiamine pyrophosphate, the active form of the vitamin known as thiamine (also spelled thiamin), or vitamin B-1 (see the image below). Thiamine pyrophosphate, the biologically active form of thiamine, acts as a coenzyme in carbohydrate metabolism through the decarboxylation of alpha ketoacids.
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- Thioglycolate (thio) broth contains Sodium thioglycolate, a reducing agent that creates anaerobic conditions when it reduces molecular oxygen to water. Dyes such as resazurin or methylene blue are usually added to the broth to provide a visual indication of the presence of oxygen.
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- Casein peptone type TT is a peptone containing all the amino acids found in casein as well as large peptide fractions. It is an excellent nutrient for use in culture media for producing toxins.Casein peptone TT was developed specifically to achieve maximal toxin production.asein peptone type III is a pancreatic digest of casein containing all the amino acids found in casein as well as larger peptide fractions. Its unique properties of digestion and high phosphate content make it the hydrolysates of choice of many organisms.
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- Nattokinase is a potent fibrinolytic enzyme extracted and highly purified from a traditional Japanese food called Natto. Research has shown Nattokinase to support the body in breaking up and dissolving the unhealthy coagulation of blood and to support fibrinolytic activity. Nattokinase may help promote:
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- (1) pentathlon Pentasaccharide in Total Hip Replacement, or Low-Molecular-Weight Heparin C. A trial comparing the efficacy and safety of a pentasaccharide fondaparinux to enoxaparin in preventing thromboembolism (TE) post elective hip replacement
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Thiamine Thiamine, also known as thiamin or vitamin B1, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat and prevent thiamine deficiency and disorders that result from it, including beriberi, Korsakoff's syndrome, and Korsakoff's psychosis. Other uses include maple syrup urine disease and Leigh's disease. It is taken by mouth or by injection.
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THIOUREA Thiourea is industrially produced by the reaction between technical-grade calcium cyanamide (CaCN2) and hydrogen sulfide (H2S) or one of its precursors in aqueous solution  e.g., ammonium sulfide ((NH4)2S) or calcium hydrogen sulfide (Ca(HS)2).
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What is sodium pentathol? Report Abuse. 1  Sodium Pentathol. 2  Sodium thiopental, better known as Sodium Pentothal (a trademark of Abbott Laboratories), thiopental, thiopentone sodium, or trapanal, is a rapid-onset short-acting barbiturate general anaesthetic. 3  Sodium pentothal is a fast acting, short duration anaesthetic & barbiturate.
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Inflammatory Bowel Disease: Serologic Markers and Pharmacogenomic and Metabolic Assessment of Thiopurine Therapy Crohn’s or UC. Get a general overview of Crohn’s disease or ulcerative colitis, all on one page. Crohn’s and Colitis 101
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TPMT TPMT. TPMT, also known as Thiopurine S-methyltransferase, is an enzyme that determines the level of 6-MMP as well as 6- TGN which are metabolites that are responsible for the potential toxicity and therapeutic aspect of thiopurine medications such as 6-MP, Azathioprine, and Imuran. [2] Thus, it is imperative that blood counts be regular tested when taking thiopurine drugs. 2  Use of thiopurines will affect the results of TPMT enzyme testing. 3  The test should be conducted PRIOR to commencing use of the drug.
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Thiamazole Methimazole (also known as Tapazole or Thiamazole or MMI) is an antithyroid drug, and part of the thioamide group. Like its counterpart propylthiouracil, a major side effect of treatment is agranulocytosis.
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- Thiamine, thiamin or vitamin B1 (/ˈθaɪ.əmɨn/ THY-ə-min), named as the thio-vitamine (sulfur-containing vitamin) is a vitamin of the B complex.First named aneurin for the detrimental neurological effects if not present in the diet, it was eventually assigned the generic descriptor name vitamin B 1.hiamine, thiamin or vitamin B1 (/ˈθaɪ.əmɨn/ THY-ə-min), named as the thio-vitamine (sulfur-containing vitamin) is a vitamin of the B complex.
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Thioglycolate broth Thioglycolate broth is a multi-purpose, enriched differential medium used primarily to determine the oxygen requirements of microorganisms. Sodium thioglycolate in the medium consumes oxygen and permits the growth of obligate anaerobes.
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THPO gene The THPO gene provides instructions for making a protein called thrombopoietin that promotes the growth and division (proliferation) of cells. This protein attaches to (binds) and turns on (activates) the thrombopoietin receptor, which stimulates several signaling pathways that transmit chemical signals from outside the cell to the cell's nucleus.
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Tetrahydrobiopterin deficiency Tetrahydrobiopterin deficiency (THBD, BH4D), also called THB or BH4 deficiency, is a rare metabolic disorder that increases the blood levels of phenylalanine. Phenylalanine is an amino acid obtained through the diet. It is found in all proteins and in some artificial sweeteners.
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- Clinical Background. Thiopurine drugs (azathioprine, 6-mercaptopurine, and 6-thioguanine) are used to treat patients with leukemia, rheumatic disease, inflammatory bowel disease, or solid organ transplant.
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Threonine Threonine (abbreviated as Thr or T) is an amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH + 3 form under biological conditions), a carboxyl group (which is in the deprotonated −COO − form under biological conditions), and a side chain containing a hydroxyl group, making it a polar, uncharged amino acid.
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- Thiamine, also known as thiamin or vitamin B 1, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat and prevent thiamine deficiency and disorders that result from it, including beriberi, Korsakoff's syndrome, and Korsakoff's psychosis. Other uses include maple syrup urine disease and Leigh's disease.