what is b-cell lymphoma
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Diffuse large B-cell lymphoma [edit on Wikidata] Diffuse large B-cell lymphoma (DLBCL or DLBL) is a cancer of B cells, a type of white blood cell responsible for producing antibodies. It is the most common type of non-Hodgkin lymphoma among adults, with an annual incidence of 7–8 cases per 100,000 people per year.
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Monoclonal and Polyclonal GammopathiesDiseases The Waldenstrom's macroglobulinemia is a rare, chronic cancer that is classified as a plasma cell neoplasm. It affects plasma cells, which develop from white blood cells called B-lymphocytes, or B cells. B cells form in the lymph nodes and the bone marrow, the soft, spongy tissue inside bones. They are an important part of the body's immune (defense) system. Some B cells become plasma cells, which make, store, and release antibodies. Antibodies help the body fight viruses, bacteria, and other foreign substances.
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Diffuse large B-cell lymphoma Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma – between 4,500 and 5,000 people are diagnosed with DLBCL each year in the UK.
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- Diffuse large B-cell lymphoma (DLBCL) is an aggressive type of non-Hodgkin lymphoma that develops from the B-cells in the lymphatic system. Under the microscope, large malignant lymphocytes are seen diffusely throughout the specimen.
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Lymphoma, Non-Hodgkin's  In-Depth Report Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL). It makes up about 30–40% of all NHL cases. DLBCL is a B-cell type of lymphoma. With DLBCL, the cancer cells appear very large and scattered throughout (diffuse) all of the lymph node or tissue when looked at under a microscope. DLBCL can occur in people of all ages, but is more common in adults in their 60s.
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B Cells B cells are a specific type of white blood cell called a lymphocyte. Other types of lymphocytes include T cells and natural killer cells. B cells develop from stem cells in bone marrow. They remain in the bone marrow until they become mature.
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- From Wikipedia, the free encyclopedia. Anaplastic large-cell lymphoma (ALCL) is a type of non-Hodgkin lymphoma involving aberrant T-cells. It is described in detail in the Classification of Tumors of the Hematopoietic and Lymphoid Tissues edited by experts of the World Health Organisation (WHO). For the cases of systemic ALCL, the recommendation is to Manage under Aggressive Lymphoma guidelines. 2  CHOP is first line of treatment, CHOP-Rituxan in the unlikely scenario that CD20 is positive, given that CD20 is a B-cell marker.
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Diffuse large B-cell lymphoma What is diffuse large B-cell lymphoma (DLBCL)? Lymphoma is a cancer of the lymphatic system, which is part of your immune system. It develops when lymphocytes (a type of white blood cell) start to divide in an uncontrolled way. There are 2 main types of lymphocytes: B lymphocytes (B cells) and T lymphocytes (T cells).
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B-Cell Lymphoma Per the 2008 revised World Health Organization (WHO) classification, B-cell malignancies are divided into two broad categories : (1) precursor B-cell neoplasms, which include B lymphoblastic leukemia/lymphoma with or without recurrent genetic abnormalities, and (2) mature B-cell neoplasms.
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- Acute lymphoblastic leukemia (ALL). Acute lymphoblastic leukemia (ALL) is a fast-growing cancer of a type of white blood cells called lymphocytes that crowds out bone marrow, preventing it from making the normal red blood cells, white blood cells, and platelets that your body needs. 1  Tweet.
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Overview B cells and T cells. Non-Hodgkin's lymphoma can begin in the: B cells. B cells fight infection by producing antibodies that neutralize foreign invaders. Most non-Hodgkin's lymphoma arises from B cells. Subtypes of non-Hodgkin's lymphoma that involve B cells include diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma and Burkitt lymphoma. T cells. T cells are involved in killing foreign invaders directly. Non-Hodgkin's lymphoma occurs less often in T cells. Subtypes of non-Hodgkin's lymphoma that involve T cells include peripheral T-cell lymphoma and cutaneous T-cell lymphoma. Whether your non-Hodgkin's lymphoma arises from your B cells or T cells helps to determine your treatment options. Where non-Hodgkin's lymphoma occurs
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B-Cell Lymphoma Non-Hodgkin lymphoma (NHL) is a collective term for a heterogeneous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment.Most NHLs (80-85%) are of B-cell origin. See the image below. Diffuse large B-cell non-Hodgkin lymphoma.
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- Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma – between 4,500 and 5,000 people are diagnosed with DLBCL each year in the UK. DLBCL is a high-grade non-Hodgkin lymphoma that has developed from B cells.
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Newly diagnosed with Lymphoma? We Can Help. Lymphoma may develop in many parts of the body, including the lymph nodes, spleen, bone marrow, blood, or other organs. Hodgkin lymphoma begins when a lymphocyte (usually a B cell) becomes abnormal. The abnormal cell is called a Reed-Sternberg cell.
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Non-Hodgkin Lymphoma Treatment Information Left untreated, these cancerous cells can form tumors, crowd out healthy white blood cells (which produce antibodies to help the body fight off infections) and ultimately weaken the body’s immune system. In general, non-Hodgkin lymphoma is broadly classified as B-cell (bone marrow) or T-cell (thymus) lymphoma.
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- B-cell CLL redirects here. For the gene family, see B-cell CLL/lymphoma. B-cell chronic lymphocytic leukemia (B-CLL), also known as chronic lymphoid leukemia (CLL), is the most common type of leukemia (a type of cancer of the white blood cells) in adults.-cell CLL redirects here. For the gene family, see B-cell CLL/lymphoma. B-cell chronic lymphocytic leukemia (B-CLL), also known as chronic lymphoid leukemia (CLL), is the most common type of leukemia (a type of cancer of the white blood cells) in adults.
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Lymphoma - Non-Hodgkin: Subtypes Diffuse large B-cell lymphoma (DLBCL). This is the most common form of lymphoma. About 30% of NHL in the United States is this type. It is an aggressive form of NHL that involves organs other than the lymph nodes about 40% of the time. About 2 out of 3 people with DLBCL are cured with chemotherapy given in combination with rituximab (Rituxan).
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Acute lymphoblastic leukemia (ALL) Acute lymphoblastic leukemia (ALL), also called acute lymphocytic leukemia or acute lymphoid leukemia, is a fast-growing cancer of a type of white blood cells called lymphocytes.
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T-Cell Lymphomas The body has two main types of lymphocytes that can develop into lymphomas: B-lymphocytes (B-cells) and T-lymphocytes (T-cells). Diffuse large B-cell lymphoma (DLBCL) is the most common form of NHL, accounting for up to 30 percent of newly diagnosed cases in the United States. DLBCL is an aggressive (fast-growing) lymphoma.
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- Knowledge center. Lymphoma is a form of cancer that affects the immune system-specifically, it is a cancer of immune cells called lymphocytes, a type of white blood cell. There are two broad types of lymphoma and many subtypes.The two types of lymphoma are described as: Hodgkin's or non-Hodgkin's.ymphatic cancers are classified by the type of immune cells affected. In non-Hodgkin's lymphoma, B-cells and T-cells are affected-both being types of lymphocyte white blood cell with special roles in immunity.
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- Lymphoma is a form of cancer that affects the immune system-specifically, it is a cancer of immune cells called lymphocytes, a type of white blood cell. There are two broad types of lymphoma and many subtypes. The two types of lymphoma are described as: Hodgkin's or non-Hodgkin's.
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B-cell lymphoma The B-cell lymphomas are types of lymphoma affecting B cells. Lymphomas are blood cancers in the lymph nodes. They develop more frequently in older adults and in immunocompromised individuals. B-cell lymphomas include both Hodgkin's lymphomas and most non-Hodgkin lymphomas. They are typically divided into low and high grade, typically corresponding to indolent (slow-growing) lymphomas and aggressive lymphomas, respectively.
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- The body has two main types of lymphocytes that can develop into lymphomas: B lymphocytes (B cells) and T lymphocytes (T cells). Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are cancers that affect the same lymphocytes.
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- In CLL, B cells grow in an uncontrolled manner and accumulate in the bone marrow and blood, where they crowd out healthy blood cells. CLL is a stage of small lymphocytic lymphoma (SLL), a type of B-cell lymphoma, which presents primarily in the lymph nodes.
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- Lymphoma is a form of cancer that affects the immune system-specifically, it is a cancer of immune cells called lymphocytes, a type of white blood cell. There are two broad types of lymphoma and many subtypes.