interleukin definition
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Definitions &Translations Freebase(0.00 / 0 votes)Rate this definition: Interleukin. Interleukins are a group of cytokines that were first seen to be expressed by white blood cells. The term interleukin derives from as a means of communication, and deriving from the fact that many of these proteins are produced by leukocytes and act on leukocytes.
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cytokine cytokine. [sī′təkīn]. one of a large group of low-molecular-weight proteins secreted by various cell types and involved in cell-to-cell communication, coordinating antibody and T cell immune interactions, and amplifying immune reactivity.ytokine. any of many small, secreted proteins such as erythropoietin, G-CSF, interferon, interleukins, that bind to cell surface receptors and transduce signals leading to the differentiation or proliferation of cells.
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cytokine Any of several regulatory proteins, such as the interleukins and lymphokines, that are released by cells of the immune system and act as intercellular mediators in the generation of an immune response.
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- Definitions for Interferon gamma. Here are all the possible meanings and translations of the word Interferon gamma. Freebase(0.00 / 0 votes)Rate this definition: Interferon gamma. Interferon gamma is a dimerized soluble cytokine that is the only member of the type II class of interferons.
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Interferon Interferon: Interferon, any of several related proteins that are produced by the body’s cells as a defensive response to viruses. They are important modulators of the immune response. Three vials filled with human leukocyte interferon.
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interleukin-1 interleukin-1 (IL-1), a protein with numerous immune system functions, including activation of resting T cells, endothelial cells, and macrophages; mediation of inflammation; and stimulation of the synthesis of lymphokines, collagen, and collagenases.
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Medical Definition of T cell Not all of their functions are known. T cells can produce substances called cytokines such as the interleukins which further stimulate the immune response. T-cell activation is measured as a way to assess the health of patients with HIV/AIDS and less frequently in other disorders.
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- Neutrophils. A type of immune cell that is one of the first cell types to travel to the site of an infection. Neutrophils help fight infection by ingesting microorganisms and releasing enzymes that kill the microorganisms. A neutrophil is a type of white blood cell, a type of granulocyte, and a type of phagocyte.
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interferon interferon in·ter·fer·on (ĭn'tər-fēr'ŏn') n. Abbr. IFN Any of a group of glycoproteins that are produced by different cell types in response to various stimuli, such as exposure to viruses, and that block viral replication in newly infected cells and, in some cases, modulate specific cellular functions.
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interferon interferon in·ter·fer·on (ĭn'tər-fēr'ŏn') n. Abbr. IFN. Any of a group of glycoproteins that are produced by different cell types in response to various stimuli, such as exposure to viruses, and that block viral replication in newly infected cells and, in some cases, modulate specific cellular functions.
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Interleukin Interleukin 3 (IL3) is a cytokine that regulates blood-cell production by controlling the production, differentiation and function of granulocytes and macrophages.
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- Medical Definition of Immunoglobulin E. Immunoglobulin E: A class of immunoglobulins that includes the antibodies that are important in an allergic response. Abbreviated IgE. A person who has an allergy often has elevated blood levels of IgE. IgE antibodies attack and engage the invading army of allergens.
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interleukin in·ter·leu·kin. n. Any of various small proteins that are produced by a variety of cell types, especially T cells and other white blood cells, and that regulate many aspects of inflammation and the immune response, including stimulating the production of white blood cells and platelets. interleukin.
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Autocrine signaling An example of an autocrine agent is the cytokine interleukin-1 in monocytes. When interleukin-1 is produced in response to external stimuli, it can bind to cell-surface receptors on the same cell that produced it.n example of an autocrine agent is the cytokine interleukin-1 in monocytes. When interleukin-1 is produced in response to external stimuli, it can bind to cell-surface receptors on the same cell that produced it.
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Glossary of HIV/AIDS-related Terms: Eosinophil: A normal type of white blood cell that has coarse granules within its cytoplasm. Eosinophils are produced in the bone marrow and migrate to tissues throughout the body. When a foreign substance enters the body, other types of white blood cells (lymphcytes and neutrophils) release substances to attract eosinophils and then release toxic substances to kill the invader. The numbers of eosinophils in blood often rise when an allergic reaction occurs.
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Macrophages: The 'defense' cells that help throughout the body The release of interleukin-4 in response to tissue injury not only results in macrophages that specialize in wound-healing, it allows the macrophages to convert arginine to ornithine, which is a precursor of polyamines and collagen.
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What are Cytokines? Cytokines are cell signalling molecules that aid cell to cell communication in immune responses and stimulate the movement of cells towards sites of inflammation, infection and trauma.
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- Each of these variations changes a single protein building block (amino acid) in interleukin-1 alpha. It is unclear how these variations alter the protein's function. Studies suggest that the effects of IL1A variations are probably related to the role of interleukin-1 alpha in promoting inflammation.
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Sepsis, An Undercover Killer When the body is under “attack” by an invader (bacteria or virus), the immune system kicks into high gear. One of the molecules that helps regulate the immune response is interleukin-6 (IL6), and is at its highest levels just two hours after infection sets in.
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- Forms of biological therapy include monoclonal antibodies, interferon, interleukin-2 (IL-2), and several types of colony-stimulating factors (CSF, GM-CSF, G-CSF). Interleukin-2 and interferon are BRMs being tested for the treatment of advanced malignant melanoma. Interferon is a BRM now in use to treat hepatitis C.tanercept (Enbrel) and infliximab (Remicade) are examples of commercially available injectable TNF-blocking treatments for patients with moderate to severe rheumatoid arthritis and other forms of inflammatory arthritis. The side effects of biological therapy depend on the type of treatment.
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interferon interferon. 1  Biochemistry. any of various proteins, produced by virus-infected cells, that inhibit reproduction of the invading virus and induce resistance to further infection. 2  Pharmacology..
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What are Cytokines? Examples of cytokines include the agents interleukin and the interferon which are involved in regulating the immune system's response to inflammation and infection. There is debate among experts over whether certain molecules should be called hormones or cytokines.
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Drug-induced acute interstitial nephritis Acute interstitial nephritis (AIN) is an entity in which acute kidney injury (AKI) is accompanied by histological findings of interstitial inflammation, edema, and tubulitis. There are allergic/drug-induced, infectious, autoimmune/systemic, and idiopathic forms of disease.
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- Interferons are proteins that have antiviral, antiproliferative, and immunomodulatory effects. Published reports indicate that after IFN-a treatment with 5 million U/day or 10 million U 3 times per week subcutaneously (SC) for 4 months, HBV DNA levels and HBeAg become undetectable in 30-40% of patients.
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- noun. Any of a class of proteins present in the serum and cells of the immune system, which function as antibodies: she was given intravenous immunoglobulin [count noun]: they are susceptible to infection in spite of high concentrations of immunoglobulins.More example sentences.ny of a class of proteins present in the serum and cells of the immune system, which function as antibodies: she was given intravenous immunoglobulin [count noun]: they are susceptible to infection in spite of high concentrations of immunoglobulins. More example sentences.
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- interneuron in·ter·neu·ron (ĭn'tər-nur'ŏn', -nyur'-) n. A nerve cell found entirely within the central nervous system that acts as a link between sensory neurons and motor neurons. in'ter·neu'ro·nal (-nur'ə-nəl, -nyur'-, -nu-rō'-, -nyu-) adj.