what is axonal neuropathy
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Giant axonal neuropathy Giant axonal neuropathy is a rare, autosomal recessive neurological disorder that causes disorganization of neurofilaments. Neurofilaments form a structural framework that helps to define the shape and size of neurons and are essential for normal nerve function.iant axonal neuropathy has an autosomal recessive pattern of inheritance. Giant axonal neuropathy results from mutations in the GAN gene, which codes for the protein gigaxonin. This alters the shape of the protein, changing how it interacts with other proteins when organizing the structure of the neuron.
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Glossary of Terms Peripheral neuropathy: A problem with the functioning of the nerves outside the spinal cord. Symptoms of peripheral neuropathy may include numbness, weakness, burning pain (especially at night), and loss of reflexes.eripheral neuropathy: A problem with the functioning of the nerves outside the spinal cord. Symptoms of peripheral neuropathy may include numbness, weakness, burning pain (especially at night), and loss of reflexes.
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Peripheral Neuropathy Peripheral neuropathy (PN) is a disease of the peripheral nerves. These are all the nerves except for the brain and spinal cord. About 30% of people with HIV develop PN. Some PN is a breakdown of the nerve endings (axons) that send sensations to the brain. Sometimes, PN is damage to the coating of nerve fibers (myelin). This affects the transmission of pain signals to the brain.
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Autonomic Nervous System - Introduction A Peripheral neuropathy is a collection of disorders in which peripheral nerve fibers, which carry signals to and from the central nervous system (the brain and spinal cord), become damaged. Diabetes is the most common cause. Typically, nerve fibers in the hands and/or feet are affected.
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- Diabetic peripheral neuropathy (DPN) is a disease whose symptoms are related to. dysfunction of peripheral nerves, such as demyelination, axonal atrophy, blunted regenerative. potential, and loss of peripheral nerve fibers, that occur specifically in patients with diabetes. (Farmer et al., 2012).
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- The nerves are reporting the shin damage to your brain. Neuropathy is a term that means pathology or abnormality with the nerves. The symptoms of neuropathy – which can include tingling, numbness, burning, weakness and sensations of pain – indicate that the nerve itself is impacted or damaged.
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polyradiculoneuropathy A nontraumatic, usually sporadic, generalized disorder of nerve roots and peripheral nerves, which may affect motor fibers or sensory fibers, but usually both, although often not to the same degree; classified as axon degenerating (axonal) or demyelinating.
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What is Neuropathy? 10 hilariously insightful foreign words. Neuropathy describes a condition in which a person suffers from peripheral nerve damage often associated with an underlying disease. Though not a disease itself, neuropathy is diagnosed in many people for whom no pre-existing cause can be determined.
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TYPE 2 DIABETES AND AMPUTATION Definition of Diabetic neuropathy. Diabetic neuropathy: Nerve damage caused by diabetes that leads to numbness and sometimes pain and weakness in the hands, arms, feet, and legs. Diabetic neuropathy can affect the digestive tract, heart, and genitalia. The longer a person has diabetes, the greater the risk of neuropathy. There are four types of diabetic neuropathy: peripheral, autonomic, proximal, and focal. Peripheral neuropathy, the most common, causes pain or loss of feeling in the hands, arms, feet, and legs.
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Axon An axon (from Greek ἄξων axōn, áxōn), axis is a, long slender projection of a nerve, cell or, neuron that typically conducts electrical impulses away from the'neuron s cell. Body myelinated axons are known as nerve. fibersxon dysfunction causes many inherited and acquired neurological disorders which can affect both the peripheral and central neurons. An axon is one of two types of protoplasmic protrusions that extrude from the cell body of a neuron, the other type being dendrites.
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- Knowledge center. Neuropathy is the term used to describe a problem with the nerves, usually the 'peripheral nerves' as opposed to the 'central nervous system' (the brain and spinal cord). Neuropathy is seen with a number of different underlying medical conditions.ore detail and supporting information is in the main article. 1  Neuropathy is a common condition. 2  Neuropathy is a complication of a number of different medical conditions. 3  Three types of nerve can be involved; autonomic nerves, motor nerves and sensory nerves.
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Understanding Neuropathy Neuropathy is a term that means pathology or abnormality with the nerves. The symptoms of neuropathy – which can include tingling, numbness, burning, weakness and sensations of pain – indicate that the nerve itself is impacted or damaged. Causes and Symptoms of Neuropathy.
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- Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected.
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Neuropathy Neuropathy is a term that refers to general diseases or malfunctions of the nerves. Nerves at any location in the body can be damaged from injury or disease. Neuropathy is often classified according to the types or location of nerves that are affected.
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axonal degeneration ax·o·nal de·gen·er·a·tion. a type of peripheral nerve fiber response to insult, wherein axon death and subsequent breakdown occur, with secondary breakdown of the myelin sheath associated; caused by focal injury to peripheral nerve fibers; often referred to as wallerian degeneration.
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Peripheral Neuropathy Peripheral neuropathy (PN) is a disease of the peripheral nerves. These are all the nerves except for those in the brain and spinal cord. About 30% of people with HIV develop PN. Some PN is a breakdown of the nerve endings (axons) that send sensations to the brain.
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Neuropathy, Neuropathic Pain, and Painful Peripheral Neuropathy: Painful peripheral neuropathy is a common neurological disorder characterized by numbness, weakness, tingling and pain, often starting in the hands or feet. The American Chronic Pain Association estimates that more than 15 million people in the U.S. and Europe have some degree of neuropathic pain.
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- Peripheral neuropathy is a type of damage to the nervous system. Specifically, it occurs when there is a problem with your peripheral nervous system, the network of nerves that transmits information from your central nervous system (your brain and spinal cord) to the rest of your body.pecifically, it occurs when there is a problem with your peripheral nervous system, the network of nerves that transmits information from your central nervous system (your brain and spinal cord) to the rest of your body.
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- Since auditory neuropathy is characterized by normal outer hair cell function and abnormal function in the region of the inner hair cells and/or auditory nerve, the appropriate auditory tests are those sensitive to cochlear and auditory nerve function.uditory neuropathy is a term presently used to describe a condition, found in some patients ranging in age from infants to adults, in which the patient displays auditory characteristics consistent with normal outer hair cell function and abnormal neural function at the level of the VIIIth (vestibulo-cochlear) nerve.
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Neuropathy Autonomic neuropathy: Autonomic neuropathy is damage to the nerves of the involuntary nervous system. These nerves that control the heart and circulation (including blood pressure), digestion, bowel and bladder function, the sexual response, and perspiration. Nerves in other organs may also be affected.
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What is hereditary neuropathy? A hereditary neuropathy is an inherited (runs in families) disorder of the peripheral nervous system (nerves away from the brain and spinal cord). There are many different hereditary neuropathies. Symptoms of a hereditary neuropathy may include: 1  Muscle weakness (especially in the foot and leg). 2  Foot deformities.
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New Recommendations for Preventing and Managing Neuropathy, Fatigue, Depression, and Anxiety Key Messages: 1  Peripheral neuropathy is a type of nerve damage that can cause numbness, tingling, pain, muscle weakness, and other changes. 2  It can be caused or worsened by cancer and cancer treatment, as well as other conditions.
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Bradypnea Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected.t can also be genetic (present from birth) or idiopathic (no known cause). In conventional medical usage, the word neuropathy (neuro- , nervous system and-pathy, disease of) without modifier usually means peripheral neuropathy.
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Peripheral Neuropathy Peripheral neuropathy, in the broadest sense, refers to a range of clinical syndromes affecting a variety of peripheral nerve cells and fibers, including motor, sensory, and autonomic fibers (Box 1).eripheral neuropathy, in the broadest sense, refers to a range of clinical syndromes affecting a variety of peripheral nerve cells and fibers, including motor, sensory, and autonomic fibers (Box 1).
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peripheral neuropathy Medical Definition of PERIPHERAL NEUROPATHY. : a disease or degenerative state (as polyneuropathy) of the peripheral nerves in which motor, sensory, or vasomotor nerve fibers may be affected and which is marked by muscle weakness and atrophy, pain, and numbness. a disease or degenerative state of the peripheral nerves in which motor, sensory, or vasomotor nerve fibers may be affected and which is marked by muscle weakness and atrophy, pain, and numbness.