what is idiopathic nephrotic syndrome
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- The type of nephrotic syndrome that is most common in children is called idiopathic nephrotic syndrome. It accounts for about 90 percent of children with nephrotic syndrome. Idiopathic means that a disease occurs with no known cause.The most common type of idiopathic nephrotic syndrome is called minimal-change nephrotic syndrome (MCNS). Idiopathic nephrotic syndrome is more common in boys than girls.With MCNS, the child usually has relapses of the illness, but the disease can usually be managed and prognosis is good.ephrotic syndrome is characterized by the following symptoms that result from changes that occur to the small, functional structures in the kidneys, such as: Very high levels of protein in the urine. Low levels of protein in the blood due to its loss in the urine.
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Overview of Nephrotic Syndrome Nephrotic syndrome is most common in young children, usually idiopathic, and most often minimal change disease. In adults, nephrotic syndrome is usually secondary, most often to diabetes or preeclampsia. Consider nephrotic syndrome in patients, particularly young children, with unexplained edema or ascites. Confirm nephrotic syndrome by finding spot protein/creatinine ratio ≥ 3 or urinary protein ≥ 3 g/24 h.
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Nephrotic syndrome Primary causes of nephrotic syndrome are usually described by their histology: 1  Minimal change disease (MCD): is the most common cause of nephrotic syndrome in children. 2  Focal segmental glomerulosclerosis (FSGS): is the most common cause of nephrotic syndrome in adults.
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Nephrotic syndrome Nephrotic syndrome is a nonspecific kidney disorder characterized by three signs of disease: large proteinuria, hypoalbuminemia and edema.Essentially, loss of protein through the kidneys (proteinuria) leads to low protein levels in the blood (hypoalbuminemia), which causes water to be drawn into soft tissues (edema).ephrotic syndrome is characterized by large proteinuria 2), hypoalbuminemia hyperlipidaemia, and edema (which is generalized and also known as anasarca or dropsy) that begins in the face. Lipiduria (lipids in urine) can also occur, but is not essential for the diagnosis of nephrotic syndrome.
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Nephrotic Syndrome Nephrotic syndrome can also result from systemic diseases that affect other organs in addition to the kidneys, such as diabetes, amyloidosis, and lupus erythematosus. Nephrotic syndrome may affect adults and children of both sexes and of any race. It may occur in typical form, or in association with nephritic syndrome.
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Idiopathic Pulmonary Fibrosis Idiopathic pulmonary fibrosis (IPF) is a type of lung disease that results in scarring (fibrosis) of the lungs for an unknown reason.
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Hematuria in Adults Idiopathic hematuria. Idiopathic means that no specific cause can be found for blood in the urine. Idiopathic hematuria can run in families, and is called familial idiopathic hematuria. When there is not a family history of kidney failure and other medical tests are negative; usually, no treatment is needed.
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What Does Idiopathic Peripheral Neuropathy Mean? High blood sugars somehow damage the nerves -- we don't completely understand. Idiopathic neuropathy means that something has happened to your little peripheral nerves -- that they're not working right, and we just don't know the answer. You're feeling a real pain, or numbness, or tingling, or whatever you may be feeling, but we don't have an explanation for it, and it's rather common.
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History History. The first sign of nephrotic syndrome in children is usually swelling of the face; this is followed by swelling of the entire body. Adults can present with dependent edema. Foamy urine may be a presenting feature. A thrombotic complication, such as deep venous thrombosis of the calf veins or even a pulmonary embolus, may be the first clue indicating nephrotic syndrome. Additional historical features can be related to the cause of nephrotic syndrome.
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Ludovico Sforza Ludovico Sforza was born on July 27, 1452, at Vigevano, in what is now Lombardy. He was the second son of Francesco I Sforza and Bianca Maria Visconti and, as such, was not expected to become ruler of Milan.
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What Is Idiopathic Pain? Idiopathic pain (also called pain of unknown origin) is the term doctors use for chronic (long-term) pain, lasting 6 months or longer, that has no identifiable cause. Although its origin is often a mystery, idiopathic pain is very real. Persistent idiopathic facial pain, featuring stabbing or burning pain in the face with no identifiable nerve or tissue damage, is an example of idiopathic pain.
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Juvenile idiopathic arthritis Juvenile idiopathic arthritis refers to a group of conditions involving joint inflammation (arthritis) that first appears before the age of 16. This condition is an autoimmune disorder, which means that the immune system malfunctions and attacks the body's organs and tissues, in this case the joints.heumatoid factor negative polyarticular juvenile idiopathic arthritis (also known as polyarthritis, rheumatoid factor negative) is also characterized by arthritis in five or more joints within the first 6 months of the disease. Individuals with this type, however, test negative for rheumatoid factor in the blood.
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- Nephrotic syndrome is a group of symptoms that include protein in the urine, low blood protein levels, high cholesterol levels, high triglyceride levels, and swelling.
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What is IIH? Read more about Diagnosis & Treatments Idiopathic Intracranial Hypertension (IIH) is a neurological condition of unknown cause defined by increased intracranial pressure (ICP) around the brain without the presence of tumour or disease.
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- Definition of idiopathic. 1  1 : arising spontaneously or from an obscure or unknown cause : primary idiopathic epilepsy. 2  2 : peculiar to the individual.
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Idiopathic Polyneuropathy Idiopathic Polyneuropathy. Idiopathic sensory-motor polyneuropathy is an illness where sensory and motor nerves of the peripheral nervous system are affected and no obvious underlying etiology is found. In many respects, the symptoms are very similar to diabetic polyneuropathy.n idiopathic sensory-motor polyneuropathy, the patients may experience unusual sensations (paresthesias), numbness and pain in their hands and feet. In addition, there may be weakness of the muscles in the feet and hands.
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Nephrotic syndrome Minimal change disease (MCD): is the most common cause of nephrotic syndrome in children. It owes its name to the fact that the nephrons appear normal when viewed with an optical microscope as the lesions are only visible using an electron microscope. Another symptom is a pronounced proteinuria.
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Medical Terminology A patient's kidney disease was labeled as idiopathic. This means that the cause of this patient's kidney disease is
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- Nephrogenic systemic fibrosis (NSF) or nephrogenic fibrosing dermopathy (NFD)[1] is a rare and serious syndrome that involves fibrosis of skin, joints, eyes, and internal organs. The first cases were identified in 1997 and its cause is not fully understood.
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Nephrotic syndrome A few other characteristics seen in nephrotic syndrome are: The most common sign is excess fluid in the body due to the serum hypoalbuminemia. Lower serum oncotic pressure causes fluid to accumulate in the interstitial tissues. Sodium and water retention aggravates the edema.
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NEPHROTIC SYNDROME, TYPE 1; NPHS1 A number sign (#) is used with this entry because nephrotic syndrome type 1 (NPHS1), also known as Finnish congenital nephrosis, is caused by homozygous or compound heterozygous mutation in the gene encoding nephrin (NPHS1; 602716) on chromosome 19q13.
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- Idiopathic Polyradiculoneuritis in Dogs. Acute canine idiopathic polyradiculoneuritis (ACIP) is a creeping paralysis due to acute inflammation of the nerves. This disease is often seen in dogs that live in North America as well as in those areas where raccoons are present but overall incidence is quite low.
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polyneuropathy acute idiopathic polyneuropathy. see idiopathic polyradiculoneuritis. distal polyneuropathy of Birman cats. a noninflammatory, diffuse loss of myelinated fibers in the distal portions of the central and peripheral nervous systems, resulting in progressive hindlimb ataxia and hypermetria in young Birman kittens.
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Congenital nephrotic syndrome Congenital nephrotic syndrome is a very rare form of nephrotic syndrome. It occurs predominantly in families of Finnish origin and manifests shortly after birth. It is an inherited disorder. The condition is caused by a defect in the protein nephrin, which is found in the kidney.
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- As a result, fluid builds up in the tissues and causes swelling. Nephrotic syndrome is often caused by: A type of kidney disease called minimal change disease (or nil disease). This is the main cause of nephrotic syndrome in children. Doctors don't know what causes minimal change disease. Diabetes. This is the most common cause of nephrotic syndrome in adults.
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Nephrogenic systemic fibrosis Nephrogenic systemic fibrosis or nephrogenic fibrosing dermopathy (NFD) is a rare and serious syndrome that involves fibrosis of skin, joints, eyes, and internal organs. The first cases were identified in 1997 and its cause is not fully understood. However, evidence suggests NSF is associated with exposure to gadolinium in patients with severe kidney failure. Epidemiological studies suggest that the incidence of NSF is unrelated to gender, ethnicity, or age and it is not thought to have a geneti