what is cystic fibrosis and what causes it
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Overview Causes. In cystic fibrosis, a defect (mutation) in a gene changes a protein that regulates the movement of salt in and out of cells. The result is thick, sticky mucus in the respiratory, digestive and reproductive systems, as well as increased salt in sweat.Many different defects can occur in the gene.n cystic fibrosis, a defect (mutation) in a gene changes a protein that regulates the movement of salt in and out of cells. The result is thick, sticky mucus in the respiratory, digestive and reproductive systems, as well as increased salt in sweat. Many different defects can occur in the gene.
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- Cystic fibrosis is a genetic condition caused by a faulty gene (known as the CFTR gene). The CFTR gene normally creates a protein that moves salt and water out of a cell.If the CFTR gene is defective, it results in a build-up of thick, sticky mucus in the body's tubes and passageways.These blockages damage the lungs, digestive system and other organs, resulting in inflammation (swelling) and, in the lungs, repeated infections.f the CFTR gene is defective, it results in a build-up of thick, sticky mucus in the body's tubes and passageways. These blockages damage the lungs, digestive system and other organs, resulting in inflammation (swelling) and, in the lungs, repeated infections.
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- Common Name(s). Cystic Fibrosis. Cystic fibrosis (CF) is an inherited condition that causes mucus to build up and clog some of the organs in the body, particularly in the lungs and pancreas. When mucus clogs the lungs, it can make breathing very difficult.ystic Fibrosis. Cystic fibrosis (CF) is an inherited condition that causes mucus to build up and clog some of the organs in the body, particularly in the lungs and pancreas.
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Cystic fibrosis Cystic fibrosis (CF), also known as mucoviscidosis, is a genetic disorder that affects mostly the lungs but also the pancreas, liver, kidneys and intestine.he main signs and symptoms of cystic fibrosis are salty-tasting skin, poor growth, and poor weight gain despite normal food intake, accumulation of thick, sticky mucus, frequent chest infections, and coughing or shortness of breath. Males can be infertile due to congenital absence of the vas deferens.
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Cystic fibrosis In people with cystic fibrosis, the body produces mucus that is abnormally thick and sticky. This abnormal mucus can clog the airways, leading to severe problems with breathing and bacterial infections in the lungs. These infections cause chronic coughing, wheezing, and inflammation.ystic fibrosis is an inherited disease characterized by the buildup of thick, sticky mucus that can damage many of the body's organs. The disorder's most common signs and symptoms include progressive damage to the respiratory system and chronic digestive system problems.
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Cystic Fibrosis URL of this page: //medlineplus.gov/ency/article/000107.htm. Cystic fibrosis is a disease that causes thick, sticky mucus to build up in the lungs, digestive tract, and other areas of the body. It is one of the most common chronic lung diseases in children and young adults. It is a life-threatening disorder. Cystic fibrosis (CF) is a disease that is passed down through families.
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Everything you need to know about cystic fibrosis Cystic fibrosis is a hereditary disease that causes the body to produce thick and sticky mucus that can clog the lungs and obstruct the pancreas. This genetic disease can be life threatening, and affects an estimated 30,000 children and adults in the US, with around 1,000 new cases diagnosed each year.
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cystic fibrosis The gene that, when defective, causes CF is called the cystic fibrosis transmembrane conductance regulator (CFTR) gene. A defect in this single gene causes all the consequences of CF. There are over 1,600 known defects in the CFTR gene that can cause CF.he glands most affected are those in the pancreas and respiratory system and the sweat glands. Cystic fibrosis is usually recognized in infancy or early childhood, chiefly among Caucasians. The earliest manifestation is meconium ileus, an obstruction of the small bowel by viscid stool.
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Cystic Fibrosis Cystic Fibrosis. Cystic fibrosis (CF) is a progressive, lifelong condition in which the glands that produce mucus, sweat, and intestinal secretions do not function properly.Thick mucus accumulates in the lungs, leading to breathing difficulty and infection.hile some babies with CF still die in infancy, many patients with CF live into their 20s and 30s. Because Cystic Fibrosis affects all ethnic groups and is one of the most common recessive genetic diseases, screening is available to anyone planning a pregnancy.
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- Cystic fibrosis (SIS-tik fi-BRO-sis), or CF, is an inherited disease of the secretory (see-KREH-tor-ee) glands. Secretory glands include glands that make mucus and sweat. Inherited means the disease is passed from parents to children through genes.
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- How to Use This Exploration. Cystic fibrosis is a fatal inherited disease of humans. Those who suffer from it secrete a thick mucus that clogs the passages of the lungs, pancreas, and liver.The result, when untreated, is fatal. Studying the disease, scientists have learned that the buildup of mucus is caused by a disruption of water balance in the body's cells.A mutation in the so-called cf gene (cf stands for cystic fibrosis) is the culprit, causing mucus buildup by preventing chloride ions from entering the cells.Chloride ions must pas through chloride channels in the cell membrane, channels which remain closed in individuals with cystic fibrosis.ow to Use This Exploration. Cystic fibrosis is a fatal inherited disease of humans. Those who suffer from it secrete a thick mucus that clogs the passages of the lungs, pancreas, and liver.
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Cystic Fibrosis Cystic fibrosis (CF) is an inherited life-threatening disease that affects many organs. It causes changes in the electrolyte transport system which causes cells to absorb too much sodium and water. CF is characterized by problems in the glands that produce sweat and mucus.
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- Cystic fibrosis (CF) is a genetic disorder. It is caused by an abnormal gene that is passed from parent to child. It is a lifelong illness that affects all of the organs of the body and often causes problems with digestion and breathing. It does not affect a person’s looks or mental ability.ystic fibrosis (CF) is a genetic disorder. It is caused by an abnormal gene that is passed from parent to child. It is a lifelong illness that affects all of the organs of the body and often causes problems with digestion and breathing. It does not affect a person’s looks or mental ability.
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- Cystic fibrosis is an inherited disease which causes mucus in the lungs to be more sticky than normal, leading to frequent lung infections and lung damage. Pneumococcus is a type of bacteria that can cause infection throughout the body, including in the urine, blood stream, fluid around the brain and in the lungs.ntibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis. Stenotrophomonas maltophilia is a bacteria which is resistant to several antibiotics. Over the last 10 years this bacteria has increasingly been found in the lungs of people with cystic fibrosis.
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What Is Cystic Fibrosis? Cystic fibrosis is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe over time. In people with CF, a defective gene causes a thick, sticky buildup of mucus in the lungs, pancreas, and other organs. In the lungs, the mucus clogs the airways and traps bacteria leading to infections, extensive lung damage, and eventually, respiratory failure.
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Cystic Fibrosis Cystic fibrosis is a serious genetic condition that causes severe damage to the respiratory and digestive systems. This damage often results from a buildup of thick, sticky mucus in the organs. Cystic fibrosis affects the cells that produce sweat, mucus, and digestive enzymes.
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- Cystic fibrosis is a hereditary disease that causes the body to produce thick and sticky mucus that can clog the lungs and obstruct the pancreas. This genetic disease can be life threatening, and affects an estimated 30,000 children and adults in the US, with around 1,000 new cases diagnosed each year. Cystic fibrosis is most commonly diagnosed via a sweat test. 2  There are over 1,900 known mutations of the cystic fibrosis gene. 3  Even people with the same gene variation can have vastly different phenotypes, causing significant differences in symptoms and prognosis. 4  There is currently no absolute cure for cystic fibrosis.
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- The cause of cystic fibrosis (CF) is a defect in a gene called the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This gene makes a protein that controls the movement of salt and water in and out of the cells in your body.
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Cystic Fibrosis Back to Top Causes. Cystic fibrosis (CF) is caused by a defective gene which causes the body to produce abnormally thick and sticky fluid, called mucus. This mucus builds up in the breathing passages of the lungs and in the pancreas, the organ that helps to break down and absorb food.ack to Top Causes. Cystic fibrosis (CF) is caused by a defective gene which causes the body to produce abnormally thick and sticky fluid, called mucus. This mucus builds up in the breathing passages of the lungs and in the pancreas, the organ that helps to break down and absorb food.
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- Cystic fibrosis is a genetic disease that causes mucus in the body to become thick and sticky. This glue-like mucus builds up and causes problems in many of the body's organs, especially the lungs and the pancreas.
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Overview Cystic fibrosis. Overview. Cystic fibrosis In cystic fibrosis, the airways fill with thick, sticky mucus, making it difficult to breathe. The thick mucus is also an ideal breeding ground for bacteria and fungi. Cystic fibrosis is an inherited disorder that causes severe damage to the lungs, digestive system and other organs in the body. Cystic fibrosis affects the cells that produce mucus, sweat and digestive juices. These secreted fluids are normally thin and slippery.
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cystic fibrosis cystic fibrosis. Cystic fibrosis (CF) is an inherited disease that affects the lungs, digestive system, sweat glands, and male fertility. Its name derives from the fibrous scar tissue that develops in the pancreas, one of the principal organs affected by the disease.ystic fibrosis affects the body's ability to move salt and water in and out of cells. This defect causes the lungs and pancreas to secrete abnormally thick mucus that blocks passageways and prevents proper function.
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What Is Cystic Fibrosis? In people with CF, a defective gene causes a thick, buildup of mucus in the lungs, pancreas and other organs. In the lungs, the mucus clogs the airways and traps bacteria leading to infections, extensive lung damage and eventually, respiratory failure.ystic fibrosis is a genetic disease. People with CF have inherited two copies of the defective CF gene -- one copy from each parent. Both parents must have at least one copy of the defective gene. People with only one copy of the defective CF gene are called carriers, but they do not have the disease.
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What Are Sharpey's Fibres? Of the nearly 40 types of fiber constructions holding the body together, only four are named after their discovers: Mullers, Mahaim, Purkinje and Sharpey's fibres. The term Sharpey's fibres actually refers to two types of fibers in the body. One is part of the microscopic web holding the teeth to the gums. The other helps the body resist strain in the cranium and down the spine.