```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>(t) Cough-Acute upper respiratory infections of multiple or unspecified sites@13:44:40</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <subquery_constraint>
        <first_query>
            <query_id>Event 1</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </first_query>
        <operator>LESS</operator>
        <second_query>
            <query_id>Event 2</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </second_query>
    </subquery_constraint>
    <subquery>
        <query_id>Event 1</query_id>
        <query_type>EVENT</query_type>
        <query_name>Event 1</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>1</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>3</hlevel>
                <item_name>Cough</item_name>
                <item_key>\\ICD10_ICD9\Diagnoses\(R00-R99) Symp~mt2x\(R00-R09) Symp~evaq\(R05) Cough\</item_key>
                <item_icon>FA</item_icon>
                <tooltip>Diagnoses \ Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (r00-r99) \ Symptoms and signs involving the circulatory and respiratory systems (r00-r09)
 \ Cough</tooltip>
                <class>ENC</class>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
    <subquery>
        <query_id>Event 2</query_id>
        <query_type>EVENT</query_type>
        <query_name>Event 2</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>1</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>4</hlevel>
                <item_name>Acute upper respiratory infections of multiple or unspecified sites</item_name>
                <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Respiratory system (460-519)\Acute respiratory infections (460-466)\(465) Acute upper respiratory inf~\</item_key>
                <item_icon>FA</item_icon>
                <tooltip>Diagnoses \ Respiratory system \ Acute respiratory infections \ Acute upper respiratory infections of multiple or unspecified sites</tooltip>
                <class>ENC</class>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
</ns4:query_definition>

```

I want to find patients who have been diagnosed with cough and acute upper respiratory infections of multiple or unspecified sites, with both events occurring within the same instance number (encounter) and the cough event happening before the acute upper respiratory infection event. The specificity scale is set to 0, indicating a broad search, and the accuracy scale for both panels is 10, meaning a high level of accuracy is desired. The query will search for these events in the ICD10_ICD9 Diagnoses, Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (r0-r9), and Symptoms and signs involving the circulatory and respiratory systems (r0-r09) for cough, and the i2b2 Diagnoses, Respiratory system, Acute respiratory infections for acute upper respiratory infections of multiple or unspecified sites.