```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>(t) Cough-Acute upper respiratory infections of multiple or unspecified sites@13:44:40</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <subquery_constraint>
        <first_query>
            <query_id>Event 1</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </first_query>
        <operator>LESS</operator>
        <second_query>
            <query_id>Event 2</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </second_query>
    </subquery_constraint>
    <subquery>
        <query_id>Event 1</query_id>
        <query_type>EVENT</query_type>
        <query_name>Event 1</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>1</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>3</hlevel>
                <item_name>Cough</item_name>
                <item_key>\\ICD10_ICD9\Diagnoses\(R00-R99) Symp~mt2x\(R00-R09) Symp~evaq\(R05) Cough\</item_key>
                <item_icon>FA</item_icon>
                <tooltip>Diagnoses \ Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (r00-r99) \ Symptoms and signs involving the circulatory and respiratory systems (r00-r09)
 \ Cough</tooltip>
                <class>ENC</class>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
    <subquery>
        <query_id>Event 2</query_id>
        <query_type>EVENT</query_type>
        <query_name>Event 2</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>1</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>4</hlevel>
                <item_name>Acute upper respiratory infections of multiple or unspecified sites</item_name>
                <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Respiratory system (460-519)\Acute respiratory infections (460-466)\(465) Acute upper respiratory inf~\</item_key>
                <item_icon>FA</item_icon>
                <tooltip>Diagnoses \ Respiratory system \ Acute respiratory infections \ Acute upper respiratory infections of multiple or unspecified sites</tooltip>
                <class>ENC</class>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
</ns4:query_definition>

```

I want to find patients who have been diagnosed with cough and acute upper respiratory infections of multiple or unspecified sites at any time during their medical history, with the cough event occurring before the acute upper respiratory infection event. The specificity scale is set to 0, meaning that the search will be less restrictive, and the accuracy scale is set to 10, indicating a high level of confidence in the results. The query will search for these two events within the same instance number, meaning that they occurred during the same encounter or visit. The first subquery is for the cough event, and the second subquery is for the acute upper respiratory infection event. The tooltip for the cough event describes the diagnosis as symptoms and signs involving the circulatory and respiratory systems, while the tooltip for the acute upper respiratory infection event describes the diagnosis as acute upper respiratory infections of multiple or unspecified sites. Both events are classified as ENC, which stands for Encounter.