```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Admit Diagnosis@23:01:48</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>2</hlevel>
            <item_name>Metabolic and immunity disorders</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Metabolic and immunity disorders (270-279)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Metabolic and immunity disorders</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Admit Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Admit Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Metabolic and immunity disorders (270-279)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find all patients with a metabolic and immunity disorder diagnosis (ICD codes 270-279) as their admit diagnosis, with a high level of specificity (100%), and without any time constraints (ANY timing). The query should be applied to the first panel of the analysis, and the result should include only unique occurrences (1) of the specified diagnosis. The query will not be synonymous with any other items in the panel.