```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>(t) College-Left HaHigh scCollege@22:19:31</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>College grad.</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Education\College grad.\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Education \ College grad.</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Left Handed</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Hand Orientation\Left Handed\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Hand Orientation \ Left Handed</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <subquery_constraint>
        <first_query>
            <query_id>Event 1</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </first_query>
        <operator>LESS</operator>
        <second_query>
            <query_id>Event 2</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </second_query>
    </subquery_constraint>
    <subquery>
        <query_id>Event 1</query_id>
        <query_type>EVENT</query_type>
        <query_name>Event 1</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>1</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>4</hlevel>
                <item_name>High school grad.</item_name>
                <item_key>\\BIRN\BIRN\oasis\Demographics\Education\High school grad.\</item_key>
                <item_icon>LA</item_icon>
                <tooltip>oasis \ Demographics \ Education \ High school grad.</tooltip>
                <class>ENC</class>
                <constrain_by_date>
                    <date_from>1979-12-01T00:00:00.000-05:00</date_from>
                    <date_to>1990-12-01T00:00:00.000-05:00</date_to>
                </constrain_by_date>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
    <subquery>
        <query_id>Event 2</query_id>
        <query_type>EVENT</query_type>
        <query_name>Event 2</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>1</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>4</hlevel>
                <item_name>College grad.</item_name>
                <item_key>\\BIRN\BIRN\oasis\Demographics\Education\College grad.\</item_key>
                <item_icon>LA</item_icon>
                <tooltip>oasis \ Demographics \ Education \ College grad.</tooltip>
                <class>ENC</class>
                <constrain_by_date>
                    <date_from>1990-12-01T00:00:00.000-05:00</date_from>
                </constrain_by_date>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
</ns4:query_definition>

```

I want to find patients who have been identified as college graduates (College grad.) and are left-handed (Left Handed) in their demographic information, with the constraint that the date of the high school graduation event (High school grad.) occurred before the date of the college graduation event.