```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>221611_s_at (51@11:34:21</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>221611_s_at (51533)</item_name>
            <item_key>\\i2b2_EXPR\i2b2\Expression Profiles Data\Affymetrix HG-U133\221611_s_at (51533)\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>Expression Profiles Data\Affymetrix HG-U133\221611_s_at (51533)</tooltip>
            <class>ENC</class>
            <constrain_by_value>
                <value_operator>LT</value_operator>
                <value_constraint>35</value_constraint>
                <value_unit_of_measure>ratio</value_unit_of_measure>
                <value_type>NUMBER</value_type>
            </constrain_by_value>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find all instances where the expression value of the gene 21611_s_at (5153) in the Affymetrix HG-U13 dataset is less than 35, with a specificity scale of 0 and an accuracy scale of 100, across all time points in the dataset.