```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Principal Diagn@21:38:17</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>1</hlevel>
            <item_name>Neoplasms (c00-d49)</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(C00-D49) Neop~k3n8\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Neoplasms (c00-d49)</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Principal Diagnosis</modifier_name>
                <modifier_key>\\ICD10_ICD9\Principal Diagnosis\</modifier_key>
                <applied_path>\Diagnoses\(C00-D49) Neop~k3n8\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find all neoplasm diagnoses (codes C0-D49) from the ICD10 and ICD9 classification systems, with any timing, and with a specificity scale of 0, panel timing of ANY, panel accuracy scale of 100, and the invert flag set to 0. The query is named "Principal Diagnosis" and the results will be constrained by the "Principal Diagnosis" modifier, with the applied path set to "Diagnoses\(C0-D49) Neoplasms\%".