```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Ess-Cho-Dis-Ant-Fem@10:49:04</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Essential hypertension</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Circulatory system (390-459)\Hypertensive disease (401-405)\(401) Essential hypertension\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Circulatory system \ Hypertensive disease \ Essential hypertension</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Cholesterol (Group:CHOL)</item_name>
            <item_key>\\i2b2_LABS\i2b2\Labtests\LAB\(LLB16) Chemistry\(LLB17) Lipid Tests\CHOL\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Labtests \ Chemistry \ Lipid Tests \ Cholesterol (Group:CHOL)</tooltip>
            <class>ENC</class>
            <constrain_by_value>
                <value_operator>GT</value_operator>
                <value_constraint>200</value_constraint>
                <value_unit_of_measure>mg/dl</value_unit_of_measure>
                <value_type>NUMBER</value_type>
            </constrain_by_value>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>3</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Disorders of lipoid metabolism</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Metabolic and immunity disorders (270-279)\(272) Disorders of lipoid metabol~\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Metabolic and immunity disorders \ Disorders of lipoid metabolism</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>4</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>1</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>2</hlevel>
            <item_name>Antihyperlipidemic agents</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME5) antihyperlipidemic agents\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>medications \ antihyperlipidemic agents</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>5</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Female</item_name>
            <item_key>\\i2b2_DEMO\i2b2\Demographics\Gender\Female\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>Demographic \ Gender \ Female</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find female patients with a diagnosis of essential hypertension and a cholesterol level greater than 200 mg/dL who have a diagnosis of disorders of lipoid metabolism and have not been prescribed antihyperlipidemic agents.