```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Circulatory system-Acute Rheumatic fever@14:33:52</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>1</hlevel>
            <item_name>Circulatory system</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Circulatory system (390-459)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Circulatory system</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Admit Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Admit Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Circulatory system (390-459)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>1</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Acute Rheumatic fever</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Circulatory system (390-459)\Acute Rheumatic fever (390-392)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Circulatory system \ Acute Rheumatic fever</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find all instances where "Circulatory system" is diagnosed with "Acute Rheumatic fever" as the primary diagnosis, and the time frame is not restricted. The query is set to have a high specificity scale of 100, meaning it is very specific and will only return results that match this exact condition. The query is also not inverted, meaning it will only return positive results. The query will look for this combination of diagnoses in the "Diagnoses" section of the patient's chart.