```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>(t) Cough-Acute upper respiratory infections of multiple or unspecified sites@15:20:25</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <subquery_constraint>
        <first_query>
            <query_id>Event 1</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </first_query>
        <operator>LESS</operator>
        <second_query>
            <query_id>Event 2</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </second_query>
    </subquery_constraint>
    <subquery>
        <query_id>Event 1</query_id>
        <query_type>EVENT</query_type>
        <query_name>Event 1</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>1</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>3</hlevel>
                <item_name>Cough</item_name>
                <item_key>\\ICD10_ICD9\Diagnoses\(R00-R99) Symp~mt2x\(R00-R09) Symp~evaq\(R05) Cough\</item_key>
                <item_icon>FA</item_icon>
                <tooltip>Diagnoses \ Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (r00-r99) \ Symptoms and signs involving the circulatory and respiratory systems (r00-r09)
 \ Cough</tooltip>
                <class>ENC</class>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
    <subquery>
        <query_id>Event 2</query_id>
        <query_type>EVENT</query_type>
        <query_name>Event 2</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>1</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>4</hlevel>
                <item_name>Acute upper respiratory infections of multiple or unspecified sites</item_name>
                <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Respiratory system (460-519)\Acute respiratory infections (460-466)\(465) Acute upper respiratory inf~\</item_key>
                <item_icon>FA</item_icon>
                <tooltip>Diagnoses \ Respiratory system \ Acute respiratory infections \ Acute upper respiratory infections of multiple or unspecified sites</tooltip>
                <class>ENC</class>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
</ns4:query_definition>

```

I want to find patients who have been diagnosed with both "Cough" and "Acute upper respiratory infections of multiple or unspecified sites" in the same encounter. The cough diagnosis should be more specific (ICD10_ICD9 code range R00-R9) and the acute upper respiratory infections diagnosis should be from the i2b2 Diagnoses code range 465. The query will be more accurate when the two events occur in the same instance (SAMEINSTANCENUM).