```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Female@18:51:39</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Female</item_name>
            <item_key>\\i2b2_DEMO\i2b2\Demographics\Gender\Female\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>Demographic \ Gender \ Female</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Male</item_name>
            <item_key>\\i2b2_DEMO\i2b2\Demographics\Gender\Male\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>Demographic \ Gender \ Male</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find all female patients in the i2b2 database with any timing and specificity scale set to 0, using the Demographics panel with accuracy scale set to 100 and no inversion, focusing on the 'Female' item with a class of ENC, and excluding the 'Male' item with the same class and settings.