```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Endocri-Ear dis@19:28:22</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>0</hlevel>
            <item_name>(PrevQuery)Endocrine by Ag@17:21:49</item_name>
            <item_key>masterid:3123</item_key>
            <tooltip>Endocrine by Ag@17:21:49</tooltip>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Ear disorders</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Neurologic Disorders (320-389)\Ear disorders (380-389)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Neurologic Disorders \ Ear disorders</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find patients with endocrine disorders and ear disorders within a specific time frame. The first panel, Endocrine by Ag@17:21:49, will search for patients with endocrine disorders, while the second panel, Ear disorders, will search for patients with ear disorders. Both panels will be combined to create a cohort of patients with both conditions. The specificity scale is set to 0, indicating that all patients with either condition will be included, and the accuracy scale is set to 100, meaning that the results will be highly accurate. The query timing is set to ANY, meaning that the time frame is not restricted.