```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Essential (prim@17:23:54</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Essential (primary) hypertension</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(I00-I99) Dise~3w8h\(I10-I15) Hype~5igm\(I10) Essentia~sbwm\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Diseases of the circulatory system (i00-i99) \ Hypertensive diseases (i10-i15) \ Essential (primary) hypertension</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>2</hlevel>
            <item_name>Diabetes mellitus (e08-e13)</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(E00-E89) Endo~c157\(E08-E13) Diab~1uxc\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Endocrine, nutritional and metabolic diseases (e00-e89) \ Diabetes mellitus (e08-e13)</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find patients with a primary diagnosis of essential hypertension (I10) and those with a secondary diagnosis of diabetes mellitus (E08-E13). The specificity scale is set to 0, meaning that the search will return all relevant records regardless of the specificity level. The time frame is set to ANY, indicating that the search will cover all available data. The accuracy scale is set to 100, indicating that the search will prioritize accurate results. The panel includes two items: the first item searches for essential (primary) hypertension in the Diagnoses section under the Diseases of the circulatory system (i0-i9) and Hypertensive diseases (i10-i15), while the second item searches for diabetes mellitus in the Diagnoses section under Endocrine, nutritional, and metabolic diseases (e0-e89). The panel is set to inverted, meaning that the results will be excluded from the overall search results. The total number of occurrences for each item is set to 1.