```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Chronic-Gender@21:34:24</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>2</hlevel>
            <item_name>Chronic lower respiratory diseases (j40-j47)</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(J00-J99) Dise~45pn\(J40-J47) Chro~fbox\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Diseases of the respiratory system (j00-j99) \ Chronic lower respiratory diseases (j40-j47)</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>2</hlevel>
            <item_name>Gender</item_name>
            <item_key>\\i2b2_DEMO\i2b2\Demographics\Gender\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Demographic \ Gender</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find all instances of chronic lower respiratory diseases (ICD10 codes J40-J47) and gender in the i2b2 database. The query will search for any occurrence of these diagnoses regardless of time, and the panel accuracy scale is set to 100. The query will include two panels, one for chronic lower respiratory diseases and another for gender. The tooltip for the first panel indicates it is looking for diagnoses related to diseases of the respiratory system, specifically chronic lower respiratory diseases, while the second panel is focused on demographic information, specifically gender. The query does not have any synonyms or inverted search parameters.