```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Essenti-Diabete@17:23:12</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Essential (primary) hypertension</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(I00-I99) Dise~3w8h\(I10-I15) Hype~5igm\(I10) Essentia~sbwm\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Diseases of the circulatory system (i00-i99) \ Hypertensive diseases (i10-i15) \ Essential (primary) hypertension</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>1</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>2</hlevel>
            <item_name>Diabetes mellitus (e08-e13)</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(E00-E89) Endo~c157\(E08-E13) Diab~1uxc\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Endocrine, nutritional and metabolic diseases (e00-e89) \ Diabetes mellitus (e08-e13)</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find patients who have been diagnosed with Essential (primary) hypertension (I10) and do not have Diabetes mellitus (E08-E13) in their medical records. The search will include any timing and has an accuracy scale of 100 for both panels. The first panel focuses on diagnoses related to diseases of the circulatory system (i0-i9) and specifically essential (primary) hypertension (I10), while the second panel excludes patients with a diagnosis of Diabetes mellitus (e08-e13) from the results.