```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Status -Status @12:50:53</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Status 1</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Socioeconomic Status\Status 1\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Socioeconomic Status \ Status 1</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>4</hlevel>
            <item_name>Some college</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Education\Some college\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Education \ Some college</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>4</hlevel>
            <item_name>Left Handed</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Hand Orientation\Left Handed\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Hand Orientation \ Left Handed</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Appendicitis</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Digestive system (520-579)\Appendicitis (540-543)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Digestive system \ Appendicitis</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Admit Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Admit Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Digestive system (520-579)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Appendicitis</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Digestive system (520-579)\Appendicitis (540-543)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Digestive system \ Appendicitis</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Secondary Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Secondary Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Digestive system (520-579)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Status 2</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Socioeconomic Status\Status 2\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Socioeconomic Status \ Status 2</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>4</hlevel>
            <item_name>Right Handed</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Hand Orientation\Right Handed\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Hand Orientation \ Right Handed</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Appendicitis</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Digestive system (520-579)\Appendicitis (540-543)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Digestive system \ Appendicitis</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Admit Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Admit Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Digestive system (520-579)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Appendicitis</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Digestive system (520-579)\Appendicitis (540-543)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Digestive system \ Appendicitis</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Secondary Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Secondary Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Digestive system (520-579)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find patients with the diagnosis of appendicitis in the primary or secondary diagnosis category, along with their handedness (left or right) and socioeconomic status (Status 1 or Status 2). Additionally, I want to include demographic information such as their level of education (e.g., some college) and hand orientation (left or right handed). The query will be applied to all visits with any timing accuracy and will return a total of one occurrence for each patient.