```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>(t) Diabete-AtorvasAntihypAnencep@11:49:21</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>6</hlevel>
            <item_name>Diabetes mellitus type II [non-insulin dependent type] [NIDDM type] [adult-onset type] or unspecified type, not stated as uncontrolled, with unspecified complication</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Endocrine disorders (240-259)\Other endocrine gland diseases (250-259)\(250) Diabetes mellitus\(250-9) Diabetes with unspecified~\(250-90) Diabetes mellitus type I~\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ ... \ Diabetes mellitus type II [non-insulin dependent t{..}cified type, not stated as uncontrolled, with unspecified complication</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Atorvastatin</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME5) antihyperlipidemic agents\(LME8) HMG-CoA reductase inhibitors\atorvastatin\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>medications \ antihyperlipidemic agents \ hmg-coa reductase inhibitors \ atorvastatin</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <subquery_constraint>
        <first_query>
            <query_id>Observation A</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </first_query>
        <operator>LESS</operator>
        <second_query>
            <query_id>Observation B</query_id>
            <join_column>STARTDATE</join_column>
            <aggregate_operator>FIRST</aggregate_operator>
        </second_query>
    </subquery_constraint>
    <subquery>
        <query_id>Observation A</query_id>
        <query_type>EVENT</query_type>
        <query_name>Observation A</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>0</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>2</hlevel>
                <item_name>Antihyperlipidemic agents</item_name>
                <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME5) antihyperlipidemic agents\</item_key>
                <item_icon>FA</item_icon>
                <tooltip>medications \ antihyperlipidemic agents</tooltip>
                <class>ENC</class>
                <item_is_synonym>false</item_is_synonym>
            </item>
        </panel>
    </subquery>
    <subquery>
        <query_id>Observation B</query_id>
        <query_type>EVENT</query_type>
        <query_name>Observation B</query_name>
        <query_timing>SAMEINSTANCENUM</query_timing>
        <specificity_scale>0</specificity_scale>
        <panel>
            <panel_number>0</panel_number>
            <panel_timing>SAMEINSTANCENUM</panel_timing>
            <panel_accuracy_scale>100</panel_accuracy_scale>
            <invert>0</invert>
            <total_item_occurrences>1</total_item_occurrences>
            <item>
                <hlevel>4</hlevel>
                <item_name>Anencephalus</item_name>
                <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Congenital anomalies (740-759)\(740) Anencephalus and similar an~\(740-0) Anencephalus\</item_key>
                <item_icon>FA</item_icon>
                <tooltip>Diagnoses \ Congenital anomalies \ Anencephalus and similar anomalies \ Anencephalus</tooltip>
                <class>ENC</class>
                <item_is_synonym>true</item_is_synonym>
            </item>
        </panel>
    </subquery>
</ns4:query_definition>

```

I want to find patients who have been diagnosed with Diabetes mellitus type II with unspecified complications and have been prescribed Atorvastatin medication, and who have also been diagnosed with Anencephalus, with the first diagnosis of Anencephalus occurring before the first prescription of Atorvastatin.