```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Essen-Diabe-PATIE@13:38:47</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Essential (primary) hypertension</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(I00-I99) Dise~3w8h\(I10-I15) Hype~5igm\(I10) Essentia~sbwm\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Diseases of the circulatory system (i00-i99) \ Hypertensive diseases (i10-i15) \ Essential (primary) hypertension</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>2</hlevel>
            <item_name>Diabetes mellitus (e08-e13)</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(E00-E89) Endo~c157\(E08-E13) Diab~1uxc\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Endocrine, nutritional and metabolic diseases (e00-e89) \ Diabetes mellitus (e08-e13)</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>3</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>0</hlevel>
            <item_name>PATIENT:HIVE:1000000045</item_name>
            <item_key>PATIENT:HIVE:1000000045</item_key>
            <tooltip>PATIENT:HIVE:1000000045</tooltip>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find patients with a diagnosis of essential (primary) hypertension (ICD10 code I10) and diabetes mellitus (ICD10 code E08-E13) who are also identified in the HIVE cohort (PATIENT:HIVE:100000045). The query has a specificity scale of 0, indicating that any occurrence of the conditions will be included, and the timing is set to ANY, meaning the conditions can have been diagnosed at any point in the patient's medical history. The accuracy scale for each panel is set to 100, indicating a high level of confidence in the results.