```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Chronic obstruc@11:15:00</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Chronic obstructive diseases</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Respiratory system (460-519)\Chronic obstructive diseases (490-496)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Respiratory system \ Chronic obstructive diseases</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find all patients with a diagnosis of chronic obstructive diseases in the respiratory system (codes 490-496) at any time during their medical history, with a specificity scale of 0, accuracy scale of 100, and a panel number of 1. The panel timing and query timing are set to ANY, and the panel is not inverted. This query is focused on the ENC (Encounter) class, and the item is not a synonym.