```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>221612_at (5740@16:53:22</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>221612_at (57408)</item_name>
            <item_key>\\i2b2_EXPR\i2b2\Expression Profiles Data\Affymetrix HG-U133\221612_at (57408)\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>Expression Profiles Data\Affymetrix HG-U133\221612_at (57408)</tooltip>
            <class>ENC</class>
            <constrain_by_value>
                <value_operator>LT</value_operator>
                <value_constraint>10</value_constraint>
                <value_unit_of_measure>ratio</value_unit_of_measure>
                <value_type>NUMBER</value_type>
            </constrain_by_value>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find all expression profiles from the Affymetrix HG-U13 chip dataset that have a value for the probe set 221612_at (57408) with a ratio less than 10, at any time point in the study, with a specificity scale of 0 and an accuracy scale of 100, and with a total of 1 occurrence in the dataset. The query will not be inverted and the class will be encoded as ENC.