```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Status -Status @12:30:21</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Status 1</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Socioeconomic Status\Status 1\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Socioeconomic Status \ Status 1</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>4</hlevel>
            <item_name>Some college</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Education\Some college\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Education \ Some college</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>4</hlevel>
            <item_name>Left Handed</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Hand Orientation\Left Handed\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Hand Orientation \ Left Handed</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Appendicitis</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Digestive system (520-579)\Appendicitis (540-543)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Digestive system \ Appendicitis</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Admit Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Admit Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Digestive system (520-579)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Appendicitis</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Digestive system (520-579)\Appendicitis (540-543)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Digestive system \ Appendicitis</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Secondary Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Secondary Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Digestive system (520-579)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Status 2</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Socioeconomic Status\Status 2\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Socioeconomic Status \ Status 2</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>4</hlevel>
            <item_name>Right Handed</item_name>
            <item_key>\\BIRN\BIRN\oasis\Demographics\Hand Orientation\Right Handed\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Demographics \ Hand Orientation \ Right Handed</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Appendicitis</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Digestive system (520-579)\Appendicitis (540-543)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Digestive system \ Appendicitis</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Admit Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Admit Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Digestive system (520-579)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>3</hlevel>
            <item_name>Appendicitis</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Digestive system (520-579)\Appendicitis (540-543)\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Digestive system \ Appendicitis</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Secondary Diagnosis</modifier_name>
                <modifier_key>\\i2b2_DIAG\Secondary Diagnosis\</modifier_key>
                <applied_path>\i2b2\Diagnoses\Digestive system (520-579)\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find patients with an Admit Diagnosis or Secondary Diagnosis of Appendicitis (ICD-9 code 540-543) who are either Left Handed or Right Handed, have a Socioeconomic Status of Status 1 or Status 2, and have some college education.