```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>mild de-Patient@11:25:49</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>mild dementia</item_name>
            <item_key>\\BIRN\BIRN\oasis\Clinical Measures\Clinical Dementia Rating (CDR)\mild dementia\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>oasis \ Clinical Measures \ Clinical Dementia Rating (CDR) \ mild dementia</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>1</hlevel>
            <item_name>Medications</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Medications</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Patient Instructions</modifier_name>
                <modifier_key>\\i2b2_MEDS\Medication\Instructions\</modifier_key>
                <applied_path>\i2b2\Medications\%</applied_path>
                <constrain_by_value>
                    <value_operator>CONTAINS</value_operator>
                    <value_constraint>drug</value_constraint>
                    <value_type>LARGETEXT</value_type>
                </constrain_by_value>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find patients with a diagnosis of mild dementia who have been prescribed medications for any condition, as recorded in the i2b2 Medications module, and have a specificity scale of 0, panel timing set to ANY, and an accuracy scale of 100 for each panel. The query will search for the term "mild dementia" in the OASIS Clinical Measures Clinical Dementia Rating (CDR) section, and the medications will be constrained by the modifier "Patient Instructions" with the value "drug" in the i2b2 Medications module. The query will be applied to panel 1 and panel 2, and the invert option is set to 0.