```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Essen-Diabe-Insul@14:15:39</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Essential hypertension</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Circulatory system (390-459)\Hypertensive disease (401-405)\(401) Essential hypertension\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Circulatory system \ Hypertensive disease \ Essential hypertension</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Diabetes mellitus</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Endocrine disorders (240-259)\Other endocrine gland diseases (250-259)\(250) Diabetes mellitus\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Endocrine disorders \ Other endocrine gland diseases \ Diabetes mellitus</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>3</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>5</hlevel>
            <item_name>Insulin</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME148) hormones\(LME150) antidiabetic agents\(LME152) insulin\insulin\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>medications \ hormones \ antidiabetic agents \ insulin \ insulin</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>0</hlevel>
            <item_name>Patient Set for "Outpa-Prima-Diabe-Person_#1000000045@11:39:24"Patient setFINISHED</item_name>
            <item_key>patient_set_coll_id:6485</item_key>
            <tooltip>Patient Set for "Outpa-Prima-Diabe-Person_#1000000045@11:39:24"Patient setFINISHED</tooltip>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find patients with a diagnosis of essential hypertension, diabetes mellitus, and who have been prescribed insulin medication within a specific time frame, using the panel named "Outpa-Prima-Diabe-Person_#100000045@1:39:24"Patient setFINISHED". The specificity scale is set to 0, indicating that the query will return all possible matches, and the accuracy scale is set to 100, meaning that all items must be present for a match to be returned. The query timing is set to ANY, meaning that there is no time restriction on when the diagnosis or medication occurred. The panel number and panel timing are also set to ANY, indicating that the query will search for these conditions at any point in time. The class is set to ENC, which stands for "encounter" and the item_is_synonym is set to false, meaning that the items are not synonyms. The hlevel and item_key values provide more specific information on where to search for the diagnoses and medication within the database.