```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Patient Instruc@20:38:05</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>6</hlevel>
            <item_name>Maxair 0.2 mg/inh aerosol with adapter 3 M Pharmaceuticals</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME219) respiratory agents\(LME223) bronchodilators\(LME224) adrenergic bronchodilators\pirbuterol\00089079021\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>medications \ respiratory agents \ bronchodilators \ adrenergic bronchodilators \ pirbuterol \ maxair 0.2 mg/inh aerosol with adapter 3 m pharmaceuticals</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Patient Instructions</modifier_name>
                <modifier_key>\\i2b2_MEDS\Medication\Instructions\</modifier_key>
                <applied_path>\i2b2\Medications\%</applied_path>
                <constrain_by_value>
                    <value_operator>CONTAINS[database]</value_operator>
                    <value_constraint>%breath%</value_constraint>
                    <value_type>LARGETEXT</value_type>
                </constrain_by_value>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find all instances where the medication "Maxair 0.2 mg/inh aerosol with adapter 3 Pharmaceuticals" was prescribed to patients and the patient instructions contain the word "breath" in their description. The query is set to have a specificity scale of 0, meaning it will return all possible matches, and the accuracy scale is set to 100, indicating that all results are relevant. The timing is set to "ANY," meaning it will search for any time frame. The panel number is 1, and the panel timing is also set to ANY. The total number of occurrences is set to 1. The query will search for the medication under the category of "Medications" and will specifically look for it under the subcategories of "Respiratory Agents," "Bronchodilators," and "Adrenergic Bronchodilators." The tooltip provided is "medications \ respiratory agents \ bronchodilators \ adrenergic bronchodilators \ maxair 0.2 mg/inh aerosol with adapter 3 m