```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Cancer of colon@03:39:59</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>6</hlevel>
            <item_name>Cancer of colon</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Neoplasms (140-239)\Malignant neoplasms (140-208)\Digestive organs and peritoneum (150-159)\(153) Malignant neoplasm of colon\(153-9) Malignant neoplasm of col~\</item_key>
            <item_icon>LA</item_icon>
            <tooltip>Diagnoses \ ... \ Malignant neoplasms \ Digestive organs and peritoneum \ Malignant neoplasm of colon \ Malignant neoplasm of colon, unspecified</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find all instances of malignant neoplasm of the colon, unspecified, with a specificity scale of 0 and an accuracy scale of 100, using the i2b2 query builder with the diagnosis concept of "Cancer of colon" in the first panel, and without any synonyms. The query timing and panel timing are set to ANY, meaning that it will search for occurrences of this condition at any time during the patient's medical history.