```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Asthma-Prednis@22:01:40</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Asthma</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Respiratory system (460-519)\Chronic obstructive diseases (490-496)\(493) Asthma\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Respiratory system \ Chronic obstructive diseases \ Asthma</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Prednisolone</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME148) hormones\(LME149) adrenal cortical steroids\prednisolone\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>medications \ hormones \ adrenal cortical steroids \ prednisolone</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
        <item>
            <hlevel>4</hlevel>
            <item_name>Prednisone</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME148) hormones\(LME149) adrenal cortical steroids\prednisone\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>medications \ hormones \ adrenal cortical steroids \ prednisone</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find patients with a diagnosis of asthma who have also been prescribed either prednisolone or prednisone medication at any point in time. The specificity scale is set to 0, meaning that all occurrences of the diagnosis and medications will be included, and the accuracy scale for each panel is set to 100, indicating a high level of confidence in the results. The query is named "Asthma-Prednis@2:01:40" and contains two panels. The first panel focuses on the diagnosis of asthma, while the second panel looks for occurrences of prednisolone or prednisone medications. The panel timing is set to ANY, meaning that the query will search for any instances of the specified criteria, regardless of the time frame. The class of the items is set to ENC, which stands for Encounter, and the items are not marked as synonyms.