```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Essen-Diabe-Insul@03:53:31</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>3</hlevel>
            <item_name>Essential (primary) hypertension</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(I00-I99) Dise~3w8h\(I10-I15) Hype~5igm\(I10) Essentia~sbwm\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Diseases of the circulatory system (i00-i99) \ Hypertensive diseases (i10-i15) \ Essential (primary) hypertension</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>2</hlevel>
            <item_name>Diabetes mellitus (e08-e13)</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(E00-E89) Endo~c157\(E08-E13) Diab~1uxc\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Endocrine, nutritional and metabolic diseases (e00-e89) \ Diabetes mellitus (e08-e13)</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>3</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Insulin</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME148) hormones\(LME150) antidiabetic agents\(LME152) insulin\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>medications \ hormones \ antidiabetic agents \ insulin</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find patients with a diagnosis of essential (primary) hypertension (I10) and diabetes mellitus (E08-E13) who have been prescribed insulin (LME152) as an antidiabetic agent (LME148). The query will search for these conditions within the specified ICD10, ICD9, and i2b2 medication codes, and will have an accuracy scale of 100%.