```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Essenti-Diabete@14:07:11</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Essential hypertension</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Circulatory system (390-459)\Hypertensive disease (401-405)\(401) Essential hypertension\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Circulatory system \ Hypertensive disease \ Essential hypertension</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>4</hlevel>
            <item_name>Diabetes mellitus</item_name>
            <item_key>\\i2b2_DIAG\i2b2\Diagnoses\Endocrine disorders (240-259)\Other endocrine gland diseases (250-259)\(250) Diabetes mellitus\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Endocrine disorders \ Other endocrine gland diseases \ Diabetes mellitus</tooltip>
            <class>ENC</class>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find patients with a diagnosis of essential hypertension (Essential hypertension) and diabetes mellitus (Diabetes mellitus) within the specified time frame (ANY), with a specificity scale of 0 and a panel accuracy scale of 100, using the i2b2 query builder. The query is named "Essenti-Diabete@14:07:1" and includes two panels, one for each condition, with a total of one item occurrence for each panel. The first panel focuses on essential hypertension under the circulatory system category, while the second panel focuses on diabetes mellitus under the endocrine disorders category. The query will return patients with these diagnoses, excluding any synonyms and with no inversion applied.