```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns4:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/">
    <query_name>Ancef 10gm powder for injection SmithKline Beecham@15:36:57</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>1</hlevel>
            <item_name>Ancef 10gm powder for injection SmithKline Beecham</item_name>
            <item_key>\\i2b2_MEDS\i2b2\Medications\MUL\(LME10) anti-infectives\(LME36) cephalosporins\(LME37) first generation cephalosporins\cefazolin\00007313505\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>medications \ anti-infectives \ cephalosporins \ first generation cephalosporins \ cefazolin \ ancef 10gm powder for injection smithkline beecham</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Rx Sig</modifier_name>
                <modifier_key>\\i2b2_MEDS\Medication\RxSig\</modifier_key>
                <applied_path>\i2b2\Medications\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns4:query_definition>

```

I want to find any instances of "Ancef 10gm powder for injection SmithKline Beecham" medication within the i2b2 database, specifically within the "anti-infectives" category under "cephalosporins" and "first generation cephalosporins" subcategories, and under the "medications" category. The query is not restricted by timing, has a specificity scale of 0, and has a total of 1 item occurrence. The item is not a synonym and is constrained by the "Rx Sig" modifier with an applied path of "\i2b2\Medications\%".