```xml
<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<ns3:query_definition xmlns:ns2="http://www.i2b2.org/xsd/cell/crc/psm/1.1/" xmlns:ns4="http://www.i2b2.org/xsd/cell/crc/psm/analysisdefinition/1.1/" xmlns:ns3="http://www.i2b2.org/xsd/cell/crc/psm/querydefinition/1.1/">
    <query_name>Princip-Seconda@14:35:27</query_name>
    <query_timing>ANY</query_timing>
    <specificity_scale>0</specificity_scale>
    <panel>
        <panel_number>1</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>1</hlevel>
            <item_name>Diseases of the musculoskeletal system and connective tissue (m00-m99)</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(M00-M99) Dise~6mvn\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Diseases of the musculoskeletal system and connective tissue (m00-m99)</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Principal Diagnosis</modifier_name>
                <modifier_key>\\ICD10_ICD9\Principal Diagnosis\</modifier_key>
                <applied_path>\Diagnoses\(M00-M99) Dise~6mvn\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
    <panel>
        <panel_number>2</panel_number>
        <panel_timing>ANY</panel_timing>
        <panel_accuracy_scale>100</panel_accuracy_scale>
        <invert>0</invert>
        <total_item_occurrences>1</total_item_occurrences>
        <item>
            <hlevel>2</hlevel>
            <item_name>Dentofacial anomalies [including malocclusion] and other disorders of jaw (m26-m27)</item_name>
            <item_key>\\ICD10_ICD9\Diagnoses\(M00-M99) Dise~6mvn\(M26-M27) Dent~7r9g\</item_key>
            <item_icon>FA</item_icon>
            <tooltip>Diagnoses \ Diseases of the musculoskeletal system and connective tissue (m00-m99) \ Dentofacial anomalies [including malocclusion] and other disorders of jaw (m26-m27)</tooltip>
            <class>ENC</class>
            <constrain_by_modifier>
                <modifier_name>Secondary Diagnosis</modifier_name>
                <modifier_key>\\ICD10_ICD9\Secondary Diagnosis\</modifier_key>
                <applied_path>\Diagnoses\(M00-M99) Dise~6mvn\%</applied_path>
            </constrain_by_modifier>
            <item_is_synonym>false</item_is_synonym>
        </item>
    </panel>
</ns3:query_definition>

```

I want to find patients with a principal diagnosis of diseases of the musculoskeletal system and connective tissue (ICD codes M0-M9) and a secondary diagnosis of dentofacial anomalies [including malocclusion] and other disorders of the jaw (ICD codes M26-M27).