Other causes of chorea include Hyperthyroidism Hypoparathyroidism Hyperglycemia Systemic lupus erythematosus (SLE) that affects the central nervous system (CNS) Drugs (eg, levodopa in patients with Parkinson disease, phenytoin, cocaine, tricyclic antidepressants, oral contraceptives) Tardive dyskinesia (due to use of typical and atypical antipsychotics or other drugs that block dopamine receptors in the brain), which may manifest as chorea or dystonia independent of the other tardive syndromes such as tics, stereotypies (stereotypic movements), and akathisia (motor restlessness) Autoimmune disorders Paraneoplastic syndromes Stroke Pregnancy Sydenham chorea can occur in rheumatic fever and may be the first symptom of it.