Trichinosis must be differentiated from Acute rheumatic fever, acute arthritis, angioedema, and myositis Febrile illnesses such as tuberculosis, typhoid fever, sepsis, and brucellosis (undulant fever) Pneumonitis Neurologic manifestations of meningitis, encephalitis, and poliomyelitis Eosinophilia due to neoplasms, eosinophilic leukemia, polyarteritis nodosa, or disease caused by other migrating nematodes Treatment of Trichinosis Albendazole or mebendazole to eliminate adult worms Symptomatic treatment Anthelmintics eliminate adult Trichinella worms from the gastrointestinal tract, but once larvae encyst in skeletal muscle, treatment may not eradicate them or any associated symptoms.