Diagn Microbiol Infect Dis 83 (2): 105 - 111, 2015. doi: 10.1016 / j. diagmicrobio.2015.06.012 Treatment of Streptococcal Infections Usually penicillin Pharyngitis (See also the Infectious Diseases Society of America's 2012 Practice Guidelines for the Diagnosis and Management of Group A Streptococcal Pharyngitis and the American Heart Association's 2020 Contemporary Diagnosis and Management of Rheumatic Heart Disease statement.)