When penicillin and a beta-lactam are contraindicated, choices include Clindamycin 600 mg (7 mg / kg for children) orally every 8 hours for 10 days Clarithromycin 250 mg (7.5 mg / kg for children) orally every 12 hours for 10 days Azithromycin 500 mg (15 mg / kg for children) orally once a day for 5 days Cephalexin 500 mg (20 mg / kg for children; maximum dose is 500 mg / dose) orally every 12 hours for 10 days Cefadroxil 1000 mg (30 mg / kg for children; maximum dose is 1000 mg / dose) orally once a day or 500 mg (15 mg / kg for children; maximum dose is 500 mg / dose) every 12 hours for 10 days Because resistance of GABHS to macrolides has been detected, some authorities recommend in vitro confirmation of susceptibility if a macrolide is to be used and there is macrolide resistance in the community.