J Hepatol 68 (3): 511 - 518, 2018. doi: 10.1016 / j. jhep.2017.11.017 Key Points Risk of alcohol-related liver disease increases markedly in men if they ingest > 40 g, particularly > 80 g, of alcohol / day (eg, about 2 to 8 cans of beer, about 3 to 6 glasses of wine, or 3 to 6 shots of hard liquor) for > 10 years; risk increases markedly in women if they ingest about half that amount.