Coccidioidomycosis (San Joaquin Fever; Valley Fever) By Sanjay G Revankar, MD, Wayne State University School of Medicine Reviewed / Revised Apr 2021 | Modified Sep 2022 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Treatment Key Points More Information Topic Resources Coccidioidomycosis Coccidioidomycosis—Disseminated.. Coccidioidomycosis—Disseminated.. Coccidioidomycosis is a pulmonary or hematogenously spread disseminated disease caused by the fungi Coccidioides immitis and C posadasii; it usually occurs as an acute benign asymptomatic or self-limited respiratory infection.