Background: There are methods of evaluating residual myocardial ischemia after AMI, Holter ECG is one of methods of non-invasive procedures, feasible to do even in early stage of AMI Objectives: To study the frequency, characteristics, residual myocardial ischemia (RMI) after AMI (day 4 and day 15) by 12 leads Holter ECG Subjects and methods: All myocardial infarction patients with ST segment and Non ST segment elevation meet the WHO diagnostic criteria of AMI Methods: A cross-sectional, descriptive study. Results: 100 patients were enrolled and studied: Envidence of RMI on Holter ECG is greater in the group of multi coronary vessel disease than that of single coronary vessel disease (p = 0.02).