The updated studies in the world and the current treatment experience of this disease at Children s Hospital 1 provide some comments as follows: (a) Prednisone treatment regimens need 4 - 6 weeks a day, followed by a 6-week alternative day; (b) For frequent recurrent nephrotic syndrome, start treatment with prednisone every day. 5 - 7 days for symptoms of upper respiratory infection; (c) For frequent relapse nephrotic syndromes, recommendations and clinical experience should choose cyclosporine (relapse after discontinuation) or MMF (fewer side effects).