Prevention of Herpes Zoster A recombinant zoster vaccine is recommended for immunocompetent adults ≥ 50 years whether they have had herpes zoster or been given the older, live-attenuated vaccine or not; 2 doses of the recombinant zoster vaccine are given 2 to 6 months apart and at least 2 months after the live-attenuated vaccine (for more information, see Recommendations of the Advisory Committee on Immunization Practices for Use of Herpes Zoster Vaccines).