15 patients with head and neck squamous cell carcinoma (oral cavity, oropharynx, hypopharynx, larynx) stage III, IV without distant metastasis (M0) were interceded induction chemotherapy under TCF regimen with concurrent chemoradiotherapy with cisplatin, on days 1, 22, 43 (responsed patients) at K Hospital from Sep, 2009 to Apr, 2012.