Results: From 8/2008 to 6/2010, at the Hospital Blood Transfusion-Hematology, we conducted a survey of the correlation between polymorphism / mutation with prognosis and effective Leukemia treatment for 185 patients included 80 patients with Chronic myeloid leukemia, 53 patients with Acute Lymphoblastic leukemia for the 52 patients with Acute Myeloid Leukemia.