Variant Angina (Prinzmetal Angina) By Ranya N Sweis, MD, MS, Northwestern University Feinberg School of Medicine; Arif Jivan, MD, PhD, Northwestern University Feinberg School of Medicine Reviewed / Revised Jun 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Variant angina is angina pectoris secondary to epicardial coronary artery spasm.