For hemodialysis group, there is a positive correlation between the level of FGF-23 and the level of total calcium, Phosphorus and calcium-phosphorus accumulation; Total calcium, Ca x P level are the two most influential factors on the level of FGF-23, total calcium changes, Ca x P explain 29.7% and 18.8% respectively of change in FGF-23 level with p < 0.05.