Congenital Syphilis By Brenda L Tesini, MD, University of Rochester School of Medicine and Dentistry Reviewed / Revised Jul 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Prevention Key Points More Information Topic Resources Congenital Syphilis (Rash) Saber Shins Keratitis (Interstitial) Hutchinson Incisors Wimberger Sign Congenital syphilis is a multisystem infection caused by Treponema pallidum and transmitted to the fetus via the placenta.