The main effects of IL-15 are Induction of proliferation of T, NK, and activated B cells Induction of cytokine production and cytotoxicity of NK cells and CD8 T cells Chemotactic activity for T cells Stimulation of intestinal epithelium growth Clinical relevance of IL-15 includes Potential as an immunostimulatory agent in the treatment of cancer IL-16 is produced by helper T cells and cytotoxic T cells The main effects of IL-16 are Chemotactic activity for CD4 T cells, monocytes and eosinophils Induction of MHC class II Clinical relevance of IL-16 includes Potential to promote CD4 T cell reconstitution in patients with HIV infection IL-16 antagonists may have utility in allergic and autoimmune conditions IL-17 (A and F) is produced by Th17 cells, gamma-delta T cells, NKT cells, and macrophages.