Melioidosis (Whitmore Disease) By Larry M Bush, MD, FACP, Charles E Schmidt College of Medicine, Florida Atlantic University; Maria T Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center Reviewed / Revised Apr 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Key Points Melioidosis is an infection caused by the gram-negative bacterium Burkholderia (formerly Pseudomonas) pseudomallei.