The cytotoxic properties was examined by sulfohrodamine method and apoptogenic effects on HeLa cells by DNA fragmentation technique and antifungal properties was tested by semi-solid agar dilution method. Results: Chemical components of essential oils from rhizomes of three Zingiber species "Ngai say" were identified by GC / MS: SL essential oil contained 52.4% zerumbone and showed significantly antiproliferative activity upon HeLa cells with IC50 of 5.81 ± 0.47 µg / ml in comparison with IC50 of 17.19 ± 2.73 µg / ml of SN essential oil.