Second-generation (atypical) antipsychotics (eg, risperidone 0.5 to 3 mg orally every 12 hours, olanzapine 2.5 to 15 mg orally once a day, quetiapine 25 to 200 mg orally every 12 hours) may be preferred because they have fewer extrapyramidal adverse effects; however, long-term use may cause weight gain and hyperlipidemia and increase the risk of type 2 diabetes.