Characteristics of using colistin: starting colistin according to the antibiogram increased by 17.3%, increasing the rate of using the loading dose to 24.2%, increasing the rate of adherence to the loading dose to 38.5%, increasing the maintenance dose colistin from 6 (4 - 6) to 6 (6 - 8), an increase of 14.3% in compliance rate and a 20.8% reduction in the rate of using lower than guided doses.