Objective: To estimate the proportion of totally controlled asthma, the proportion of improvement of ≥ 4 points in St George scale, the proportion of noncompliance, and the direct healthcare cost in asthmatic and chronic obstructive pulmonary disease (COPD) patients managed according to GINA and GOLD Subjects and method: 83 patients with asthma and 40 patients with COPD at Healthcare Center of Hoc Mon District, Healthcare Center of Phu Nhuan District, and Regional General Hospital of Thu Duc District were treated according to GINA and GOLD for 12 months.