The urea reduction rate: 76.61 ± 7.37% Online Hemodiafiltration compare with 69.90 ± 7.55% conventional hemodialysis; the creatinin reduction rate: 67.76 ± 6.05% Online Hemodiafiltration compare with 61.40 ± 7.82% conventional hemodialysis; the phospho reduction rate: 52.37 ± 14.47% Online Hemodiafiltration compare with 42.81 ± 21.39% conventional hemodialysis; the Beta 2-microglobulin reduction rate: 72.42 ± 7.60% Online Hemodifiltration compare with 56.91 ± 12.76% conventional hemodialysis; the Homocysteine reduction rate: 43.23 ± 15.46% Online Hemodiafiltration compare with 33.68 ± 14.72% conventional hemodialysis.