Overview of Glaucoma By Douglas J Rhee, MD, University Hospitals / Case Western Reserve University Reviewed / Revised Apr 2023 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Treatment Key Points Topic Resources Eye: Anterior and Posterior... Aqueous humor production... Open-Angle Glaucoma: Classificati... Angle-Closure Glaucoma: Classific... Developmental Abnormalities... Glaucomas are a group of eye disorders characterized by progressive optic nerve damage in which an important part is a relative increase in intraocular pressure (IOP) that can lead to irreversible loss of vision.