303 patients recruited from type 2 diabetes mellitus patient follow up at Nhan Dan Gia Đinh hospital Ho Chi Minh City from 10/2014 to 06/2015 were randomized. All patients are tested visual acuity, intraocular pressure, microscopic examination of living with contact lenses, dilated pupils, capturing color digital retinal fundus (TOPCON TRC - NW8FJapan).