Dosage of liposomal amphotericin B is For immunocompetent patients: 3 mg / kg IV once a day for 5 days and then once a day on days 14 and 21 (total dose of 21 mg / kg) For patients with AIDS or other immunocompromising conditions: 4 mg / kg IV once a day on days 1 to 5, 10, 17, 24, 31, and 38 (total dose of 40 mg / kg) Miltefosine orally, dosed by body weight: patients 30 to 44 kg, 50 mg twice a day for 28 days or for patients ≥ 45 kg, 50 mg 3 times a day for 28 days can be used to treat immunocompetent patients who acquired L donovani in India or adjacent areas of South Asia, who are > 12 years of age, who weigh > 30 kg, and who are not pregnant or breastfeeding.