In this study, six phenolic compounds were isolated from the ethyl acetate of Cornus officinalis, including: Gallic acid (1), dimethyl malate (2), 1, 4-dimethyl ester 2 - (2-formyl-1Hpyrrol-1-yl) butanedioic acid (3), stageobester A (4), coroffester (5), and methyl caffeate (6).