Results: General anesthesia with single - lumen endotracheal intubation, and intrathoracic CO2 insufflation for treating palmar hyperhidrosis was performed successfully in all patients supine position semi Fowler with the mean age 21.28 ± 5.65 (min 11 age - max 42 age), heart rate, arterial blood pressure and respiratory stability during surgery and anesthesia. SpO2 was over 98%, mean hospital stay was 2.84 ± 0.43 days (range 2 - 4days).