Diagnosis of Ovarian Cancer Ultrasonography (for suspected early cancers) or CT or MRI (for suspected advanced cancers) Tumor markers (eg, cancer antigen [CA] 125) Ovarian cancer is suspected in women with the following: Unexplained adnexal masses Unexplained abdominal bloating Changes in bowel habits Unintended weight loss Unexplained abdominal pain An ovarian mass is more likely to be cancer in postmenopausal women.