Treatment of Myasthenia Gravis Anticholinesterase drugs to relieve symptoms Corticosteroids, immunomodulating treatments (eg, IV immune globulin [IVIG], plasma exchange), immunosuppressants, or thymectomy to lessen the autoimmune reaction Supportive care In patients with congenital myasthenia, anticholinesterase drugs and immunomodulating treatments are not beneficial and should be avoided.