Conclusions: Blood transfusion with matched antigens blood group for thalassemia and allogeneic blood stem cell transplantation patients is initially effective for patients: 239 suitable blood units were selected to transfuse for 20 patients; Cross-matching results between 239 blood units with patients' serum at 220C phase, 370C and AHG phase were also negative (100%); Average Hb, red blood cell number and Hct indexes increased with statistically significant in patients after transfusion. There was not difference between bilirubin indirect and LDH before and after transfusion.