Precipitating factors for myasthenia gravis include Infection Surgery Certain drugs (eg, aminoglycosides, quinine, magnesium sulfate, procainamide, calcium channel blockers, immune checkpoint inhibitors) Abnormal antibodies Most patients with myasthenia gravis develop antibodies to acetylcholine receptors (AChRs); these antibodies bind to AChRs on the postsynaptic membrane at the neuromuscular junction and interrupt neuromuscular transmission.