The MT1-MMP expression in multilocular ameloblastoma was significantly higher than unilocular ameloblastoma (p <0.05); MT1-MMP expression in ameloblastoma with ill - defined border was significantly higher in ameloblastoma with well - defined border (p <0.05); MT1-MMP expression in ameloblastoma with cortical perforation was significantly higher in ameloblastoma without cortical perforation (p <0.05).