Treatment of TSC Symptomatic treatment Sirolimus or everolimus Treatment of TSC is both symptomatic and specific: For seizures: Antiseizure drugs (especially vigabatrin for infantile spasms) or sometimes epilepsy surgery For skin lesions: Dermabrasion or laser techniques For neurobehavioral problems: Behavior management techniques or drugs For hypertension caused by renal problems: Antihypertensives or surgery to remove growing tumors For developmental delays: Special schooling or occupational therapy For malignant tumors and some of the benign tumors: Everolimus or sirolimus Although so far they are approved only for the treatment of subependymal giant cell astrocytomas (SEGAs), growing evidence suggests oral sirolimus and its derivative, everolimus, may be used to prevent and treat most of the complications of TSC.