In comparision with MGIT as reference test to detect Mycobacteria. tubeculosis among pulmonary tuberculosis AFB (-) co-infected with HIV have the sensitivity 66, 7%, specificity 77, 1%, positive predictive value 82, 0%, negative predictive value 59, 7% In comparision with drugs succeptibility test as referrence test to detect Rifampicin resistance Xpert MTB / RIF have the sensitivity 62, 5%, Specificity 90, 5%, Positivie predictive value 55, 6%, negative predictive value 92, 7%