Patients are at high risk of sunburn and skin cancers (especially squamous cell carcinoma) and should avoid direct sunlight, use sunglasses with ultraviolet (UV) filtration, wear sun-protective clothing with a UV protection factor of 50 or higher, and use sunscreen with a broad-spectrum sun protection factor (SPF) as high as possible (eg, 50 or higher) that protects against UVA and UVB wavelengths (see sun exposure prevention).