Based on findings from the Diabetes Prevention Program (DPP), Metformin should be recommended as an option for high-risk individuals (e. g., those with a history of Gestational Diabetes Mellitus, < 60 years olds, BMI ≥25 kg / m2 for Asian people, one of risk factors (HbA1c > 6%, IFG plus IGT, high blood pressure, HDL C < 0, 9 mmol / L, TG > 2, 52 mmol and First-degree relative with diabetes).