Curr Rheumatol Rep 19 (7): 41, 2017. doi: 10.1007 / s11926 - 017 - 0670 - 8 Diagnosis Clinical criteria Proposed diagnostic criteria for CAPS include increased markers of inflammation and at least 2 of the following: Urticarial-like rash Episodes triggered by cold and / or stress Sensorineural hearing loss Musculoskeletal symptoms, including arthralgias, arthritis, and myalgias Chronic aseptic meningitis Skeletal abnormalities, including epiphyseal overgrowth and frontal bossing These criteria have a sensitivity of 81% and specificity of 94% (1).