Result: 970 patients, there were 137 patients with nosocomial infections with 181 episodes of nosocomial infections, the overall mortality rate was 25.1% (243/970), the mortality related to nosocomial infections was 33.6% (46/137), in which the ratio of VAP 15.3/1000 days of mechanical ventilation with a mortality rate of 35.1%, CAUTI of 7.0/1000 days of catheterization and 31.4% mortality, CLABSI of 4.9/1000 days of catheterization and death 60.8%.