Ventricular Premature Beats (VPB) (Premature Ventricular Contraction; PVC) By L Brent Mitchell, MD, Libin Cardiovascular Institute of Alberta, University of Calgary Reviewed / Revised Jan 2023 View Patient Education Diagnosis Prognosis Treatment Topic Resources Ventricular Premature Beat Sinus Rhythm With Ventricular... Ventricular premature beats (VPB) are single ventricular impulses caused by reentry within the ventricle or abnormal automaticity of ventricular cells.