Metastatic Bone Tumors By Michael J Joyce, MD, Cleveland Clinic Lerner School of Medicine at Case Western Reserve University; David M Joyce, MD, Moffitt Cancer Center Reviewed / Revised Jul 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Key Points Topic Resources Metastatic Bone Tumor Metastatic Bone Cancer Lytic Metastasis in the Proximal... Lytic Metastasis in the Distal... Proximal Femoral Metastatic... Any cancer may metastasize to bone, but metastases from carcinomas are the most common, particularly those arising in the following areas: Breast Lung Prostate Kidney Thyroid Colon Prostate cancer in men and breast cancer in women are the most common types of cancers.