Our results were higher with some other studies. This difference may be due to the following reasons: firstly, the initial evaluation time selected patients with obvious symptoms or clinical manifestations, so quality of life at the beginning of the study is greatly affected; secondly, because the assessment results were compared with the starting time of the patients themself; thirdly, due to different tools for assessing quality of life, mostly using Juniper's quality of life table, combining using SF - 36 tables, or quality of life table of nationally specific; Fourth, 22 because our study only followed for 3 months, shorter than some other studies.