Results: The MLC SMEDDS formula (%) includes MLC (2.5), NaOH (0.29), water (0.58), Labrafil M 1944 CS (38.652), Kolliphor RH 40 (38.652) and Transcutol HP (19.326), having average droplet size 26.12 ± 0.15 nm, zeta potential - 4.85 ± 0.88 mV, drug release after 45 minutes 99.89 ± 0.72%.