Women with PID are usually hospitalized if any of the following are present: Uncertain diagnosis, with inability to exclude a disorder requiring surgical treatment (eg, appendicitis) Pregnancy Severe symptoms or high fever Tubo-ovarian abscess Inability to tolerate or follow outpatient therapy (eg, due to vomiting) Lack of response to outpatient (oral) treatment In these cases, IV antibiotics (see table) are started as soon as cultures are obtained and are continued until patients have been afebrile for 24 hours.