Heart 106 (4): 261 - 266, 2020. doi: 10.1136 / heartjnl-2019 - 315600 Treatment of Dyslipidemia Lifestyle changes (eg, exercise, dietary modification) For high LDL-C, statins, bile acid sequestrants, ezetimibe, bempedoic acid, and PCSK9 (proprotein convertase subtilisin / kexin type 9) inhibitors For high TG, fibrates, omega-3 fatty acids, and sometimes other measures General principles The main goal for dyslipidemia treatment is prevention of atherosclerotic cardiovascular disease (ASCVD), including acute coronary syndromes, stroke, transient ischemic attack, or peripheral arterial disease presumed caused by atherosclerosis.