Arginine Vasopressin Deficiency (Central Diabetes Insipidus) (Vasopressin-Sensitive Diabetes Insipidus) By John D Carmichael, MD, Keck School of Medicine of the University of Southern California Reviewed / Revised Apr 2023 View Patient Education Pathophysiology Etiology Symptoms and Signs Diagnosis Treatment Key Points More Information Topic Resources Common Causes of Polyuria Water Deprivation Test Results Arginine vasopressin deficiency (central diabetes insipidus) results from a deficiency of vasopressin (antidiuretic hormone [ADH]) due to a hypothalamic-pituitary disorder.