6% (40/42), one case required MTX treatment due to the rise of beta hCG after cornuostomy; Mean blood loss volume was 60 ml, Operating time was 58 minutes and no complication; The serum beta-hCG level returned to normal range in 3.4 weeks postoperatively, the duration of hospital stay was 3 days and treatment costs was 4 to 6 milions Vietnam dong. Conclusion: Laparoscopic surgery for the treatment of interstitial pregnancy is safe and efficient.