Results: From 01/2001 to 09/2006, 356 cases of exudative pleural effusions (237 male and 119 female patients) were admited and perfomed by blind percutaneous pleural biopsy for diagnosis, include 148 cases of tuberculous pleurisies, 201 pleura metastatic malignancies, 4 tuberculous pleurisies and pleura metastatic malignancies và 3 mesotheliomas.