Clindamycin 7 mg / kg orally every 8 hours is preferred in children who have relapses of chronic tonsillitis, possibly because of the following: Clindamycin has good activity against penicillinase-producing staphylococci or anaerobes coinfecting the tonsillar crypts and inactivating penicillin G. It appears to halt exotoxin production more rapidly than other medications.