Results: There were 113 patients was studded, included 17 patients with ALS, 16 patients with SMA, 22 patients with lumbar radiculopathy, 19 patients with PN, 32 patients with CTS and 7 patients with myopathy. Subjects with ALS, SMA, radiculopathy and PN in stage with normal CMAP amplitude showed clear decrement of mean MUNE values.