Pediatr Blood Cancer 48 (2): 124 - 131, 2007. doi: 10.1002 / pbc.21039 Treatment of HLH Chemotherapy, cytokine inhibitors, immune suppression, and sometimes hematopoietic stem cell transplantation Treatment for hemophagocytic lymphohistiocytosis should be started if the disorder is suspected, even if not all diagnostic criteria are fulfilled.