Carbon Monoxide Poisoning By Gerald F O'Malley, DO, Grand Strand Regional Medical Center; Rika O'Malley, MD, Grand Strand Medical Center Reviewed / Revised Jun 2022 | Modified Sep 2022 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Treatment Prevention Key Points Carbon monoxide (CO) poisoning causes acute symptoms such as headache, nausea, weakness, angina, dyspnea, loss of consciousness, seizures, and coma.