The result of study showed that there was a significant difference of the rate of G-6-PD deficiency between boy (5.3%) and girl (1.5%); ethnic minority (7.2%) and Kinh (2.2%); living in mountianous region (6.9%) and coastal region (0.0%); their mothers were hairdressers (40%) and others (3.1%) (p < 0.05).