Radionuclide Imaging of the Heart By Thomas Cascino, MD, MSc, Michigan Medicine, University of Michigan; Michael J Shea, MD, Michigan Medicine at the University of Michigan Reviewed / Revised Jul 2021 | Modified Sep 2022 View Patient Education Single-Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging Infarct Avid Imaging Radionuclide Ventriculography Topic Resources SPECT in Recent-Onset Angina Nuclear Medicine Stress Test Technetium-99 m (Tc-99) Myocardial... Radionuclide imaging uses a special detector (gamma camera) to create an image following injection of radioactive material.