Background: Lupus with renal involvement is more common in children than in adults. Anatomopathological aspects were related with severe clinical presentation in children with lupus nephritis. Objectives: The aim of the study was to describe the clinical signs, laboratory findings and treatment in Lupus children with renal involvement. Methods: We received from January 2001 to December 2008, the records of 53 children under 15 years of age with lupus nephritis hospitalized in pediatric hospital n0 2.Results: There were 53 lupus cases with renal involvement.