Classes of oral drugs used to treat hypertension include Adrenergic modifiers (beta - and alpha-antagonist, alpha-2-agonist, beta-blocker) Angiotensin-converting enzyme (ACE) inhibitors Angiotensin IIreceptor blockers (ARBs) Calcium channel blockers (CCBs) Thiazide diuretics Vasodilators For a more detailed discussion of each class and its specific drugs, see Drugs for Hypertension in Children.