Antiretroviral Treatment of HIV Infection By Edward R Cachay, MD, MAS, University of California, San Diego School of Medicine Reviewed / Revised Feb 2023 View Patient Education More Information Topic Resources Lipodystrophy (Lipoatrophy)... Lipodystrophy (Lipoatrophy)... Because disease-related complications can occur in untreated patients with high CD4 counts and because less toxic drugs have been developed, treatment with antiretroviral therapy (ART) is now recommended for all patients.