There are the association between homocysteine concentrations ≥ 10 μmol / L (OR = 4.23, 95% confidence (CI): 1.15 to 15.79, p = 0.03) and high disease activity (DAS 28> 5.1) (OR = 5.93, 95% CI: 1.18 to 29.76, p = 0.031) with the ten-year cardiovascular risks.