Effective interventions on quality of life indicators (n = 45) Index of quality of life Before treatment (X± SD) After treatment (X± SD) p Personal activities 2, 84 ± 0, 67 0, 78 ± 0, 76 <0, 001 Nose symptoms 3, 98 ± 0, 72 0, 76 ± 0, 74 <0, 001 Eye symptoms 2, 93 ± 0, 72 0, 71 ± 0, 76 <0, 001 Practice issues 2, 67 ± 0, 98 0, 67 ± 0, 71 <0, 001 Overall average quality of life score 3, 11 ± 0, 93 0, 73 ± 0, 74 <0, 001 After 3 months of treatment, quality of life scores on individual 16 activities, nasal, eye symptoms and practice as well as overall score decreased by over 70% with significant differences compared with before treatment.