Objective: To determine the HLA - A, - B, - C, - DRB1, - DRB3/4/5 and - DQB1 in the donors-recipients in the Blood Transfusion Hematology Hospital - Ho Chi Minh City. Methods: The HLA typing in 203 subjects was studied using the polymerase chain reaction-sequence specific primers (PCR-SSP). Results: A total of 14 HLA-A, 25 HLA-B, 12 HLA-C, 13 HLA-DRB1, 3 HLA-DRB3, 1 HLA-DRB1, 2 HLA-DRB5 and 6 HLA-DQB1 alleles were found.