The basic treatment of acute pancreatitis includes Early goal-directed fluid resuscitation Analgesia Nutritional support The 2013 American College of Gastroenterology (ACG) guidelines recommend that early, aggressive fluid resuscitation, defined as 250 to 500 mL / hour of isotonic crystalloid solution (ideally lactated Ringer's solution), be provided to all patients during the first 12 to 24 hours unless contraindicated by cardiovascular, renal, or other related comorbid factors.