Other complications of chronic pancreatitis include Formation of pseudocysts Obstruction of the bile duct or duodenum Disruption (disconnection) of the pancreatic duct (resulting in ascites or pleural effusion) Thrombosis of the splenic vein (can cause gastric varices) Pseudoaneurysms of arteries near the pancreas or pseudocyst Patients with chronic pancreatitis are at increased risk of pancreatic adenocarcinoma, and this risk seems to be greatest for patients with hereditary and tropical pancreatitis.