Antipsychotic Drugs By Carol Tamminga, MD, UT Southwestern Medical Dallas Reviewed / Revised Apr 2022 | Modified Sep 2022 View Patient Education Topic Resources QT Interval Correction (EKG) Conventional Antipsychotics Second-Generation Antipsychotics * Depot Antipsychotic Drugs Treatment of Acute Adverse... Abnormal Involuntary Movement... Antipsychotic drugs are divided into conventional antipsychotics and 2nd-generation antipsychotics (SGAs) based on their specific neurotransmitter receptor affinity and activity.