Training facility: Hanoi Medical University Doctoral dissertations new conclusions: Study on 80 patients admitted to the Emergency Department of Bach Mai Hospital due to intraventricular hemorrhage with acute hydrocephalus who were undergone ventriculostomy to drain CSF externally from 11/2011 to 12/2014 was aimed to evaluate the effectiveness of external intraventricular drainage (EVD) in combination with intraventricular fibrinolysis (IVF) by Alteplase in the treatment of intraventricular hemorrhage with acute hydrocephalus.