Hematopoietic Stem Cell Transplantation By Martin Hertl, MD, PhD, Rush University Medical Center Reviewed / Revised Aug 2022 | Modified Sep 2022 View Patient Education Procedure Complications Prognosis Hematopoietic stem cell (HSC) transplantation is a rapidly evolving technique that offers a potential cure for hematologic cancers (leukemias, lymphomas, myeloma) and other hematologic disorders (eg, primary immunodeficiency, aplastic anemia, myelodysplasia).