Results: 29 cases of chorionic villus sampling, 96, 5% at 11 - 12 weeks; 96, 6% sufficient villi to culture after aspirated; 39, 1% good growth in culture, 60, 9% infected in culture, 6 cases non-culture; no abnormal karyotype, 46, XX: 8 cases và 46, XY: 1 case.