Patients who are allergic to cephalosporins (including ceftriaxone) are treated with Gentamicin 240 mg IM in a single dose plus azithromycin 2 g orally in a single dose DGI with gonococcal arthritis is initially treated with IM or IV antibiotics (eg, ceftriaxone 1 g IM or IV every 24 hours, ceftizoxime 1 g IV every 8 hours, cefotaxime 1 g IV every 8 hours) continued for 24 to 48 hours once symptoms lessen, followed by oral therapy guided by antimicrobial susceptibility testing, for a total treatment course of at least 7 days.