Streptococcus pneumoniae was completely resistant to erythromycin, highly resistant to trimethoprim / sulfamethoxazole in antibiotic group A with the rate of 84.6%, completely resistant to clindamycin, completely sensitive to antibiotics in group B, C and O Bacteria that cause ear infections were mainly Staphylococcus aureus, Pseudomonas aeruginosa, Haemophilus influenza and Streptococcus pneumoniae.