Subject and Methods: 2049 patients suffering from malignant blood diseases, non-malignant blood diseases and autoimmune diseases with hematologic manifestations, the three most common groups of diseases at NIHBT are performed APTT, mixtest, LA, aCL (IgG and IgM), aβ2GPI (IgG and IgM) on the first time hospitalization and after 12 weeks for people who have APLAs.