Results: Four factors significantly associating to therapy effectiveness included age (age <60 had better glucose control than age ≥ 60 with OR: 3.74 (95% CI: 1.97 - 7.11)), HbA1c (group with HbA1c in range of (6.5% to ≤ 7.5%) had better glucose control than group with HbA1c ≤ 6.5% with OR: 1.46 (95% CI: 0.38 - 5.58), group with HbA1c > 7, 5% had lower glucose control than group with HbA1c ≤ 6.5% with OR: 0.22 (95% CI: 0.09 - 0.58)), total disease number (group with total diseases ≤ 3 had better glucose control than group with total diseases > 3 with OR: 3.92 (95% CI: 2.17 - 7.07)) and antihyperglycemia therapy (non insulin therapy had lower glucose control thaninsulin therapy with OR: 0.49 (95% CI: 0.23 - 1.03)).