Secondary outcome events were significantly higher in the frailty group, including cardiovascular death (HR = 2.7; 95% CI, 1.6 to 4.4; p < 0.001), cardiovascular re-admission (HR = 5.1; 95% CI, 3.2 to 8.3; p < 0.001), and re-admission or death due to heart failure (HR = 5.5; 95% CI, 3.3 to 9.1; p < 0.001).