The average concentrations of cytolines in rheumatoid arthritis patients is as followings: IL-1α (57.36 ± 196.43), IL-1β (123.77± 532.51), Il-2 (279.93 ± 945.04), IL-4 (279.93 ± 945.04), IL-6 (91.35 ± 170.52), IL-8 (270.84 ± 445.45), IL-10 (134.58 ± 496.14), VEGF (638.87 ± 540.18), IFN-γ (136.43 ± 338.68), TNF-α (106.27 ± 265.57), MCP1 (292.34 ± 265.52), EGF (152.62 ± 123.64). RF is correlated with IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-10, IFN-γ, and TNF-α.