Int J Parasitol Drug-Drug Resist 15: 9 - 24, 2021. doi: 10.1016 / j. ijpddr.2020.12.001 Prevention of Relapses of P vivax or P ovale Malaria Hypnozoites must be eliminated from the liver with primaquine or tafenoquine to prevent relapses of P vivax or P ovale.