Chronic Mucocutaneous Candidiasis By James Fernandez, MD, PhD, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University Reviewed / Revised Jan 2023 View Patient Education Symptoms and Signs Diagnosis Treatment Key Points Topic Resources Candidiasis (Nail Infection) Thrush Candida Esophagitis Chronic mucocutaneous candidiasis is persistent or recurrent candidal infection due to inherited T-cell defects.