Most cases of HPS are caused by The Sin Nombre, Andes, and Choclo hantaviruses Others are caused by The Black Creek Canal virus, Muleshoe virus, and Bayou virus in the southeastern United States and Mexico The New York virus (a variant of Sin Nombre virus) on the East Coast of the United States The Convict Creek virus and Isla Vista virus on the West Coast of North America The Laguna Negra (and its Rio Mamore variant), Andes-like virus Hu39694, Lechiguanas, Oran, Central Plata, Buenos Aires, Rio Mearim, Juquitiba, Juquitiba-like, Ape Aime Itapua, Araucaria, Jabora, Neembucu, Anajatuba, Castelo dos Sonhos, Maripo, and Bermejo hantaviruses in South America Infection is transmitted to humans via inhalation of excreta of sigmodontine rodents (especially the deer mouse for Sin Nombre virus).