J Clin Microbiol 56 (6): e00252 - 18, 2018. doi: 10.1128/JCM.00252 - 18 Treatment of Candidal Vaginitis Antifungal medications (fluconazole in a single oral dose preferred) Avoidance of excess moisture accumulation Keeping the vulva dry and wearing loose, absorbent cotton clothing that allows air to circulate can reduce vulvar moisture and fungal growth.