Based on PASI reduction, it is divided into some levels: Very Good: PASI down 100% o Good: PASI down 75% - <99% o Fair: PASI reduced from 50-< 75% o Moderate: PASI decreased from 25-<50% o Poor, ineffective: PASI reduction <25% - Technical principle of cytokine detection test: Using the Luminex machine system.