Data relating to visual acuity, intraocular pressures, conjunctiual bleb and complications were collected before, during and after trabeculectomy at time points as follows: 1 week, 1month, 3 months, 6months, 9 months and 12months. Results: Results of trabeculectomy after a year: Indicators MMC group 5 FU group 11 Averaged visual acuity (log MAR scale) "0.8167 ± 0.7878 0.7343 ± 0.5493 21 Averaged intraocular pressure (mmHg) 20.783 ± 2.458 21.118 ± 2.43031 The percentage of adjustment of intraocular pressure 94.1% 88.2% 41 The percentage of good and fair conjunctival bleb 87.6% 86.3% 51 The percentage of relapse 5.9% 11.8% Conclusions: Both trabeculectomy with MMC and with 5 - FU were safe for patients.