- Using vasopressor drugs: + Noradrenalin withthe initial dose of 0.05 µg / kg / min, gradually increasing the dose every 5 - 10 minutes to achieve an average blood pressure ≥ 65 mmHg, after compensating adequate fluid CVP> 8 mmHg and average blood pressure <65 mmHg and / or SVRI<1700 when conducting the procedure of PiCCO.