Drug treatment of heart failure (HF) involves symptom relief with Diuretics Nitrates Digoxin Drug treatment for long-term management and improved survival is with Angiotensin converting enzyme (ACE) inhibitors Beta-blockers Aldosterone antagonists Angiotensin IIreceptor blockers (ARBs) Angiotensin receptor / neprilysin inhibitors (ARNIs) Sodium-glucose cotransporter-2 inhibitors (SGLT2) Sinus node inhibitors All patients should be given clear and explicit information about their drugs, including The importance of timely prescription renewal The importance of adherence to therapy How to recognize adverse effects When to contact their physician Selection of drugs for heart failure Choice of drug depends on the type of heart failure along with individual patient characteristics.