Sturge-Weber Syndrome By M Cristina Victorio, MD, Akron Children's Hospital Reviewed / Revised Aug 2021 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Topic Resources Facial Port-Wine Stain Sturge-Weber syndrome is a congenital vascular disorder characterized by a facial port-wine nevus, a leptomeningeal angioma, and neurologic complications (eg, seizures, focal neurologic deficits, intellectual disability).