MI can be classified into 5 types based on etiology and circumstances: Type 1: Spontaneous MI caused by ischemia due to a primary coronary event (eg, plaque rupture, erosion, or fissuring; coronary dissection) Type 2: Ischemia due to increased oxygen demand (eg, hypertension), or decreased supply (eg, coronary artery spasm or embolism, arrhythmia, hypotension) Type 3: Related to sudden unexpected cardiac death Type 4a: Associated with percutaneous coronary intervention (signs and symptoms of myocardial infarction with cTn values > 5 × 99th percentile URL) Type 4b: Associated with documented stent thrombosis Type 5: Associated with coronary artery bypass grafting (signs and symptoms of myocardial infarction with cTn values > 10 × 99th percentile URL) Infarct location MI affects predominantly the left ventricle (LV), but damage may extend into the right ventricle (RV) or the atria.