Merkel Cell Carcinoma (Neuroendocrine Skin Carcinoma; Primary Small Cell Skin Carcinoma; Trabecular Cell Carcinoma; APUDoma of the Skin; Anaplastic Skin Cancer) By Gregory L Wells, MD, Ada West Dermatology and Dermatopathology Reviewed / Revised Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Prevention Merkel cell carcinoma is a rare, aggressive skin cancer that tends to affect older White people.