Acute nonulcerative blepharitis is usually caused by an allergic reaction involving the same area, eg, atopic blepharodermatitis and seasonal allergic blepharoconjunctivitis, which cause Intense itching and inflammation (usually along the edges of both eyelids); Rubbing (a response to itching that can increase conjunctival itching and exacerbate atopic dermatitis [eczema] of the eyelid); or Contact sensitivity (dermatoblepharoconjunctivitis) Chronic blepharitis Chronic blepharitis is noninfectious inflammation of unknown cause.