Children with microalbuminuria (albumin / creatinine ratio 30 to 300 mg / g) on repeat samples or with persistently elevated blood pressure readings (> 90th to 95th percentiles for age or ≥ 130/80 mm Hg for adolescents) who do not respond to lifestyle interventions typically require antihypertensive therapy, most commonly using an angiotensin-converting enzyme inhibitor.