Correction of coagulation disorder, GI bleeding such as red cell package transfusion 72.4% with mean one of 16.4ml / kg, fresh frozen plasma (FFP) 61.8% with mean one of 20.6ml / kg, cryoprecipitate 57.9% with mean one of 1.5 Unit/6 kg, concentrated platelet 31.6% with mean one of 1.7 Unit/10 kg;