Treatment of Echinococcosis For hepatic echinococcosis, surgical resection Percutaneous aspiration followed by instillation of a scolicidal agent and reaspiration (PAIR) Albendazole alone or in combination with surgical resection or aspiration Observation only For alveolar echinococcus, surgical resection, if possible, plus albendazole Treatment of cystic (hydatid) echinococcosis varies depending on the type, location, and number of cysts and whether imaging results indicate the cysts are active, transitional, or inactive (1).