Table Recommended Endocarditis Prophylaxis During Oral-Dental or Respiratory Tract Procedures * Route Drug and Dosage in Adults (and Children) Drug and Dosage in Adults (and Children) Allergic to Penicillin Oral (given 1 hour before procedure) Amoxicillin 2 g (50 mg / kg) Clindamycin 600 mg (20 mg / kg) or Cephalexin or cefadroxil 2 g (50 mg / kg) or Azithromycin or clarithromycin 500 mg (15 mg / kg) Parenteral (given 30 minutes before procedure) Ampicillin 2 g (50 mg / kg) IM or IV Clindamycin 600 mg (20 mg / kg) IV or Cefazolin 1 g (25 mg / kg) IM or IV * For patients without active infection.