Fanconi Syndrome By L Aimee Hechanova, MD, Texas Tech University Health Sciences Center, El Paso Reviewed / Revised May 2022 | Modified Sep 2022 View Patient Education Etiology Pathophysiology Symptoms and Signs Diagnosis Treatment Key Points Fanconi syndrome consists of multiple defects in renal proximal tubular reabsorption, causing glucosuria, phosphaturia, generalized aminoaciduria, and bicarbonate wasting.