Result: The concentration of Il-17 decreases statiscally significant, after 12 weeks from 29.89 to 23.82 (p<0.01), after 24 weeks was 6.05 (p<0.001), and hs-CRP also decreased with time with statistical significance, after 12 weeks from 8.14 to 4.27 (p<0.001) and after 24 weeks was 2.13 (p<0.001).