The common clinical characteristics in the SLE patients with positive ANCA, c-ANCA are arthritis (57.9% and 56.8%), acute skin rash - butterflu rash (26.3% and 24.3%), interstitial lung disease (26.3% and 24.3%), multi membrane effusion (34.2% and 35.1%), ulcers in skin ((18.4% và 18.9%), Raynaud (16.2% và 16.7%), C3 deficiency (97.4% and 97.3%), C4 deficiency (84.2% and 83.8%) and 100% of SLE patients who have positive ANCA, c - ANCA antibodies has positive dsDNA.