* Factors related to fatality Before continuous hemofiltration: APACHE II score, SOFA score, blood lactate, blood PTC in the fatality group are statistically significant higher than the those in survival group, p <0.05 At 48 hours of continuous hemofiltration, the IL-1b (cut-off point 3.2 ng / ml) and IL-6 (cut-off point 89.2 ng / ml) have good value in fatal prognosis with AUC of 0.783 (p = 0.007) and 0.762 (p = 0.013), respectively.