In this research, we evaluate the antiinflammatory effects of some flavonoids isolated from Wormwood: NC1 (5, 7-Dihydroxy-6, 3‟, 4‟-trimetoxy flavon), NC2 (5, 7, 3-Trihydroxy-6, 4, 5-trimetoxy flavon) to contribute to creating new materials from natural sources which have good therapeutic and few side effects.