Interdigital Neuralgia (Morton Neuroma; Morton Neuralgia) By Kendrick Alan Whitney, DPM, Temple University School of Podiatric Medicine Reviewed / Revised Oct 2021 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Key Points Topic Resources How to Examine the Foot How To Examine the Ankle Interdigital nerve irritation (neuralgia) or persistent benign enlargement of the perineurium (neuroma) can cause pain, which may be nonspecific, burning, or lancinating, or a foreign body sensation.