Nocardiosis (Nocardia) By Larry M Bush, MD, FACP, Charles E Schmidt College of Medicine, Florida Atlantic University; Maria T Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center Reviewed / Revised Mar 2023 View Patient Education Symptoms and Signs Diagnosis Treatment Prognosis Key Points Topic Resources Actinomycotic Mycetoma Actinomycetoma Nocardiosis is an acute or chronic, often disseminated, suppurative or granulomatous infection caused by various aerobic soil saprophytes of the gram-positive bacilli genus Nocardia.