Donor (deceased or living) risk factors for graft failure in the recipient include Age > 50 Hepatic steatosis Elevated liver enzymes, bilirubin, or both Prolonged stay in an intensive care unit Hypotension requiring vasopressors Hypernatremia Possibly transplantation from female donors to male recipients But because imbalance between supply and demand is greatest for liver transplants (and is growing because prevalence of hepatitis-induced cirrhosis is increasing), livers from donors > 50, livers with longer cold ischemia times, those with fatty infiltration, and those with viral hepatitis (for transplantation into recipients with viral hepatitis-induced cirrhosis) are increasingly being used.