Other common secondary causes of dyslipidemia include Diabetes mellitus Chronic kidney disease Primary biliary cirrhosis and other cholestatic liver diseases Hypothyroidism Alcohol overuse Medications, such as thiazides, beta-blockers, retinoids, highly active antiretroviral agents, cyclosporine, tacrolimus, progestins, and glucocorticoids; oral estrogens cause a mixed effect (decrease LDL-C and increase HDL-C, but also increase TGs) Secondary causes of low levels of HDL-C include cigarette smoking, anabolic steroids, HIV infection, and nephrotic syndrome.