Result: 72 Nurses who are giving direct care to HIV / AIDS patients at Nhân Ái hospital were investigated. The results were: 75.0% female and 25.0% male; secondary of nurses were 77.7%; got married were 69.5%, age group under 30 years old was 52.7%; working time from 2 - 5 years was 44.5%; Nurses who had right knowledge about HIV / AIDS which were trained in hospital were 79.1%; right knowledge about caring for infected people was 65.2%; right skill about caring for infected people was 70.8%; the number of nurses who had right attitude about HIV / AIDS had the average score under 4 was 35%. Statistical analysis showed the significant relationship between.