Ongoing hemorrhage is suggested by Worsening hemodynamic status Significant ongoing transfusion needs (eg, more than 2 to 4 units over a 12-hour period) A significant decrease in hematocrit (Hct; eg, by > 10 to 12 percentage points) The significance of transfusion requirements and change in Hct depend somewhat on the organ injured and other associated injuries (ie, that may also have caused blood loss) as well as the patient's physiologic reserves.