Infection by Escherichia coli O157: H7 and Other Enterohemorrhagic E coli (EHEC) By Larry M Bush, MD, FACP, Charles E Schmidt College of Medicine, Florida Atlantic University; Maria T Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center Reviewed / Revised Apr 2022 | Modified Sep 2022 View Patient Education Epidemiology Pathophysiology Symptoms and Signs Diagnosis Treatment Prevention Key Points The gram-negative bacteria Escherichia coli O157: H7 and other enterohemorrhagic E coli (EHEC) typically cause acute bloody diarrhea, which may lead to hemolytic-uremic syndrome.