After 3rd infusion, CI increased from 4.62 ± 2.04l / min / m2 to 4.69 ± 1.95l / min / m2; GEDVI increased from 817.23 ± 190.22ml / m2 to 873.12 ± 206.39ml / m2; SVV decreased from 12.36 ± 7.45% to 10.62 ± 5.61%.