Objectives: To explore technique and monitor of patients with dengue shock syndrome (DSS) complicated with acute respiratory failure receiving continuous positive airway pressure CPAP Design: Prospective case series study. Main results: 84 prolonged DDS children complicated with acute respiratory failure who were determined by MacELISA positive for Dengue, indicated continuous positive airway pressure CPAP, consisted of DSS (grade III) (71.4%), severe DSS (grade IV) (28.6%), mean age 6.7 years old, youngest age of 7 months.