Relationship between 1b genotype and ALT HCV genotype ALT Non-1b 1b genotype Total p n Rate (%) n Rate (%) n Rate (%) < 2 ULN 33 76.7 15 60 48 70.6 0.14 ≥ 2 ULN 10 23.3 10 40 20 29.4 Total 43 100.0 25 100.0 68 100.0 Average 60.23 ± 44.4 85.61 ± 66.71 69.56 ± 54.61 0.06 40% patients with 1b genotype had ALT ≥ 2 times of normal value, whereas in the non-1b group, the rate was only 23.3%; ALT average of 1b genotype tend to be higher than non-1b genotype, however disvrepancy was not significant.