Prevention of Genital Herpes The best ways to avoid genital herpes are Abstaining from sexual contact (vaginal, anal, and oral sex) Being in a long-term mutually monogamous relationship with a partner who has been tested and is not infected Risk of genital herpes can by reduced by Using latex condoms correctly and consistently However, condoms do not cover all areas that can be affected and thus do not fully protect against genital herpes.