Comparision of the ratio of domestic drug use in Circular 10 during the periods of 2018 and 2019 to that of 2017 by number of drug items Number of drug items 2017 (1) 2018 (2) 2019 (3) 2 P * 21 2 P * 31 NOI% NOI% NOI% Total 3 levels DD - Circular 10 809 8.19 858 8.15 821 7.66 0.01 0.90 2.03 0.15 Total drug 9, 874 10, 534 10, 723 Central DD - Circular 10 371 6.14 369 5.91 349 5.60 0.29 0.58 1.63 0.20 Total drug 6, 040 6, 246 6, 233 Provin - cial DD - Circular 10 680 7.86 706 7.77 664 7.26 0.05 0.81 2.34 0.12 Total drug 8, 650 9, 091 9, 152 District DD - Circular 10 737 9.09 787 9.05 750 8.50 0.00 0.92 1.83 0.17 Total drug 8, 108 8, 697 8, 823 (p21: 2018 compared to 2017; p31: 2019 compared to 2017 *: Using test Chi - square) Comment: The numbers of DD items under Circular 10 in 2018 and 2019 are higher than in 2017 across hospital levels.