Treatment of Relapsing Polychondritis Nonsteroidal anti-inflammatory drugs or dapsone for mild ear disease Corticosteroids Sometimes methotrexate or other immunosuppressants (eg, cyclosporine, cyclophosphamide, azathioprine, anti-tumor necrosis factor drugs) Mild recurrent ear disease may respond to nonsteroidal anti-inflammatory drugs in anti-inflammatory doses, or oral dapsone (50 to 100 mg once a day).