Criteria for early latent syphilis include during the prior year, a documented conversion from negative to positive treponemal test, a newly positive nontreponemal test, or a sustained (> 2 weeks) 4-fold or greater increase in reaginic test titers plus any of the following: Unequivocal symptoms of primary or secondary syphilis A sex partner with documented primary, secondary, or early latent syphilis No possible exposure except during the previous 12 months Patients who have latent syphilis but do not fulfill the above criteria have late latent syphilis.