Diabetes Mellitus (DM) By Erika F Brutsaert, MD, New York Medical College Reviewed / Revised Sep 2022 View Patient Education Etiology Symptoms and Signs Diagnosis Treatment Monitoring Diabetes Treatment Special Populations and Settings Prevention Key Points More Information Topic Resources Glycemic Assessment Diabetes Risk Self-Assessment Body Mass Index (Quetelet's... Cardiovascular Risk Assessment... 5-Year Risk of Cardiovascular... General Characteristics of... Diagnostic Criteria for Diabetes... Overview of Diabetes Diabetes mellitus is impaired insulin secretion and variable degrees of peripheral insulin resistance leading to hyperglycemia.