Clonorchiasis (Chinese or Oriental Liver Fluke Infection) By Chelsea Marie, PhD, University of Virginia; William A Petri, Jr, MD, PhD, University of Virginia School of Medicine Reviewed / Revised Aug 2021 | Modified Sep 2022 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Treatment Topic Resources Clonorchis life cycle Clonorchiasis is infection with the liver fluke Clonorchis sinensis.