The average concentration of vWF, VCAM-1, MCP-1, D-Dimer of acute ischemic stroke and controled groups were: vWF 177.80 ± 6.90MU / ml patient/148.98±19.04MU / ml control; VCAM-1 53.79±3.33ng / ml patient/43.91 ± 4.77 control; MCP-1 357.37 ± 111.03pg / ml patient/190.80 ± 51.6 pg / ml control, and D-Dimer 1016.72 ± 524.06ng / ml patient, 329.40 ± 90.16ng / ml control, p<0.001.