Hantavirus Infection By Thomas M Yuill, PhD, University of Wisconsin-Madison Reviewed / Revised Jun 2023 View Patient Education Hemorrhagic Fever With Renal Syndrome Symptoms and Signs Diagnosis Treatment Prognosis Hantavirus Pulmonary Syndrome Symptoms and Signs Diagnosis Treatment Prognosis More Information Hantaviridae are a family of enveloped single-stranded RNA viruses, which consists of at least 4 serotypes with 9 viruses causing 2 major, sometimes overlapping, clinical syndromes: Hemorrhagic fever with renal syndrome (HFRS) Hantavirus pulmonary syndrome (HPS) (See also Overview of Arbovirus, Arenavirus, and Filovirus Infections.)