Cyanide casualties require prompt antidotal therapy with inhaled amyl nitrite 0.2 mL (1 ampule) for 30 seconds of each minute; 3% sodium nitrite 10 mL at 2.5 to 5 mL / minute IV (in children, 10 mg / kg), then 25% sodium thiosulfate 25 to 50 mL at 2.5 to 5 mL / minute IV.