Infants with omphalocele have a very high incidence of other congenital anomalies (up to 70%), including Bowel atresia Chromosomal abnormalities (eg, trisomy 18, trisomy 13, Down syndrome [trisomy 21]) Cardiac anomalies and renal anomalies Beckwith-Wiedemann syndrome Omphalocele can be detected by routine prenatal ultrasonography; if the disorder is present, delivery should be at a tertiary care center with personnel experienced in dealing with this disorder and the other associated congenital anomalies.