Oral ciprofloxacin 500 mg 2 times a day or the combination of metronidazole (500 mg 3 times a day) and trimethoprim / sulfamethoxazole double strength (1 tablet 2 times a day) for 7 to 10 days or another broad-spectrum antibiotic can suppress overgrowth of intestinal flora and may alleviate symptoms of small intestine bacterial overgrowth, such as bloating, flatulence, and diarrhea.