Treatment of patients with hereditary angioedema focuses on 4 core principles (2): Availability of effective on-demand acute therapy for all patients Early treatment to prevent attack progression Treatment of attacks regardless of the site of swelling Incorporation of long-term prophylaxis based on highly individualized decision-making reflecting a physician-patient partnership Based on these principles, all patients with confirmed hereditary angioedema should have access to ≤ 2 standard doses of an on-demand medication for treatment of acute attacks (2).