Drug Treatment of Asthma By Victor E Ortega, MD, PhD, Mayo Clinic Arizona; Manuel Izquierdo, DO, Wake Forest Baptist Health Reviewed / Revised Mar 2022 | Modified Sep 2022 View Patient Education Topic Resources Drug Treatment of Asthma * Major drug classes commonly used in the treatment of asthma and asthma exacerbations include Bronchodilators (beta-2 agonists, anticholinergics) Corticosteroids Leukotriene modifiers Mast cell stabilizers Methylxanthines Immunomodulators Drugs in these classes (see table Drug Treatment of Chronic Asthma) are inhaled, taken orally, or injected subcutaneously or intravenously; inhaled drugs come in aerosolized and powdered forms.