The results showed that the percentage of ESBL-producing intestinal bacteria strain carrying CTX-M and TEM genes were predominant on diﬀerent type of collected samples. The corresponding rates were 47.6% and 37.0% respectively (from 265 fecal samples of healthy individual); 42.4% and 55.6% (from 125 animal fecal samples); 4.4% and 1.3% (from 160 samples of processed food), 14.8% and 13.2% (from 182 dringking water samples) respectively.