The pattern of immunoglobulin elevation adds little information, although different immunoglobulins are usually very high in different disorders: IgM in primary biliary cholangitis (previously called primary biliary cirrhosis) IgA in alcohol-related liver disease IgG in autoimmune hepatitis and viral hepatitis Antimitochondrial antibodies These heterogeneous antibodies are positive, usually in high titers, in > 95% of patients with primary biliary cholangitis.