Results: After 3 - 6 hours of intensive treatment, indexes such as pulse, average blood pressure, CVP, ScvO2, and lactate all improved significantly in the PiCCO group than in the conventional group (TQ), by 96 hours the indexes achieved treatment goals were: Pulse: 83 bpm, SBP: 82 mmHg, CVP: 11 mmHg, ScvO2: 79 mmHg, Lactate: 3.1 mmol/l.