Code: 62720149 Department: Oncology Name of Postgraduate student: HAN THI THANH BINH Science advisor: Professor NGUYEN BA DUC Associate Professor TRAN VAN THUAN The study was done at HANOI MEDICAL UNIVERSITY The contributions of the thesis * Combination chemotherapy with paclitaxel - cisplatin for treatment effect higher than etoposide - cisplatin in stage IIIB, IV in accordance with Vietnam situation.