Overview of Seronegative Spondyloarthropathies (Seronegative Spondyloarthritides) By Kinanah Yaseen, MD, Cleveland Clinic Reviewed / Revised Nov 2022 View Patient Education Seronegative spondyloarthropathies (seronegative spondyloarthritides) share certain clinical characteristics (eg, inflammatory back pain, uveitis, gastrointestinal symptoms, rashes).