The following should be considered: Pelvic MRI to determine the origin of the tumor (cervix or uterus) and local extension For high-grade carcinomas, chest, abdomen, and pelvic CT If metastatic disease is suspected based on physical examination or blood tests, positive emission tomography (PET) - CT Because endometrial cancer sometimes results from an inherited mutation, genetic counseling and / or testing should be considered if patients are < 50 years or have a significant family history of endometrial cancer, ovarian cancer, or colorectal cancer or known Lynch syndrome (HNPCC).