Copper toxicity that causes complications such as hemolytic anemia, anuria, or hepatotoxicity is also treated with chelation therapy with one of the following: Oral penicillamine 250 mg every 6 hours to 750 mg every 12 hours (1000 to 1500 mg / day in 2 to 4 doses) Dimercaprol 3 to 5 mg / kg IM every 4 hours for 2 days, then every 4 to 6 hours If used early, hemodialysis may be effective.