Schizotypal Personality Disorder (STPD) By Mark Zimmerman, MD, Rhode Island Hospital Reviewed / Revised May 2021 | Modified Sep 2022 View Patient Education Etiology Symptoms and Signs Diagnosis Treatment Schizotypal personality disorder is characterized by a pervasive pattern of intense discomfort with and reduced capacity for close relationships, by distorted cognition and perceptions, and by eccentric behavior.