Manifestations include the following: Intrauterine growth restriction Prematurity Microcephaly Jaundice Petechiae Hepatosplenomegaly Periventricular calcifications Chorioretinitis Hepatitis Pneumonitis Sensorineural hearing loss Infants who acquire CMV during or after birth, especially if they are premature, may develop a sepsis-like syndrome, pneumonia, hepatosplenomegaly, hepatitis (which can lead to liver failure), thrombocytopenia, and atypical lymphocytosis.