Objectives: The aims of this single-blind, randomized clinical study were first to evaluate clinical efficacy of a polishing paste containing 8% arginine and calcium carbonate in reducing dentin hypersensitivity immediately, two and four weeks after the application and secondly to compare two methods of applying this product into interdental zones: by micro applicators and by interdental brush. Methods: The study included subjects having air blast test score of 1 or 2 or 3 (Schiff Cold Air Sensitivity Scale).