Drugs for Inflammatory Bowel Disease By Aaron E Walfish, MD, Mount Sinai Medical Center; Rafael Antonio Ching Companioni, MD, HCA Florida Gulf Coast Hospital Reviewed / Revised Jan 2022 | Modified Sep 2022 View Patient Education 5-Aminosalicylic Acid (5-ASA, Mesalamine) Corticosteroids Immunomodulating Drugs Biologic Agents Antibiotics and Probiotics Several classes of drugs are helpful for inflammatory bowel disease (IBD).