Objectives: To investigate the prevalence and risk factors of malnutrition in head and neck cancer (HNC) patientsMethod: A prospective study of 101 patients admitted to Head and Neck Surgery Department in Ho Chi Minh city Oncology Hospital. Results: The prevalence of malnutrition according to BMI, SGA, PGSGA, serum Albumin is 16.8%, 14.6%, 8.9%, 5%, respectively.