Often, oxycodone / acetaminophen 1 or 2 tablets (each tablet can contain 2.5 to 10 mg oxycodone and 325 to 650 mg acetaminophen) orally every 4 to 6 hours or morphine 2 to 4 mg IV every 3 hours is given as a starting dose, which is subsequently adjusted as needed; individual needs and tolerances can vary several-fold.