Objective: to evaluate results of operative and nonoperative procedure were used to treate main bile duct injuries (BDI) from cholecystectomy. Patients and method: Patients, who were treated main bile duct injuries from open cholecystectomy and laparocholecystectomy in Cho Ray hospital from 1.2000 to 10.2006, were collected retrospectively and analysed Results: there were 53 cases BDI from cholecystectomy, 19 cases (35.85%) were treated nonoperatively (medicine, ERCP) with postcholecystectomy bile leak and biliary-enteric anastomosis leak, early results were good and excellent (32.08%), medium (3.77%), 9 of 19 patients were followed up average time 29.4 moths ± 7.8 (12 - 38 months) with good and excellent result.