Purpose: To study the clinical features and the operation of tumors in the head of the pancreas. Materials and methods: From January 2006 to September 2009, six patients of tumors in the head of the pancreas who underwent Whipple at Children Hospital No1 & Children Hospital No2 HCMC were evaluated retrospectively. Results: There were 5 girls and 1 boy ranging in age from 5 to 13 years.