The results of the whole exome sequencing showed that all cases have at least one of the following mutations: ASXL1, CEBPA, IDH2, KIT, KRAS, RUNX1, TET2, TP53, DNMT3A, IDH1, NPM1, FLT3, and NRAS; Of these, 14/19 cases (73.7%) with ≥ 2 coexisting mutations in the list above.