Skene Duct Cyst (Skene's Duct Cyst) By Kilpatrick, MD, MEd, Baylor College of Medicine Reviewed / Revised Feb 2023 View Patient Education Diagnosis Treatment Key Points Topic Resources Vulvar Anatomy Skene Gland (Paraurethral)... Skene duct cysts develop adjacent to the distal urethra, sometimes causing perineal discharge, dyspareunia, or abscess formation.