Lincosamides, Oxazolidinones, and Streptogramins By Brian J Werth, PharmD, University of Washington School of Pharmacy Reviewed / Revised May 2022 | Modified Sep 2022 View Patient Education Topic Resources Mechanisms of Action: Protein... Lincosamides (clindamycin), oxazolidinones (linezolid, tedizolid), and streptogramins (dalfopristin [streptogramin A] and quinupristin [streptogramin B]) are structurally different but are grouped together because they have a similar mode of antibacterial action and similar antibacterial spectra.