In multivariable analysis, AST, GGT and platelet were independent predictors of significant fibrosis with odds ratio 1.49 (95% confidence interval (Cl), 1.02 to 1.67), 1.28 (95% Cl, 1.06 to 1.55) and 0.58 (95% Cl, 0.35 - 0.95), respectively.