This study was designed to evaluate the role of percutaneous transhepatic biliary drainage (PTBD) and stent placement in biliary obstruction. Objectives: To evaluate biliary depression efficacy and complications of PTBD and stent placement procedures. Method: Prospective description, from 1 - 2008 to 8 - 2009 at University Medical Center. Result: 55 cases of malignant obstructive jaundice were performed PTBD or stent placement.