Congenital Toxoplasmosis By Brenda L Tesini, MD, University of Rochester School of Medicine and Dentistry Reviewed / Revised Jul 2022 | Modified Sep 2022 View Patient Education Etiology Symptoms and Signs Diagnosis Prognosis Treatment Prevention Key Points Topic Resources Congenital Toxoplasmosis Congenital toxoplasmosis is caused by transplacental acquisition of Toxoplasma gondii.