Brugada Syndrome By L Brent Mitchell, MD, Libin Cardiovascular Institute of Alberta, University of Calgary Reviewed / Revised Jan 2023 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Treatment Prevention Key Points More Information Topic Resources Type 1 Brugada ECG pattern Brugada syndrome is an inherited channelopathy causing an increased risk of ventricular tachycardia (VT) and ventricular fibrillation (VF) leading to syncope and sudden death.