Objectives: In recent years, BNP and NT-proBNP is emerging as biomarkers play a key role in the treatment and prognosis of cardiovascular disease has been recognized in the diagnosis of heart failure and now this biomarker important in assessing cardiac dysfunction and prognostic value in patients with acute myocardial infarction, the domestic and international research shows that BNP and NT-proBNP increased rapidly and soon provide information on prognosis so we also aims to study the role of NT-proBNP in the short-term prognosis of acute myocardial infarction and stable angina.