Result: Group P had systolic, diastolic and mean blood pressure just before cardiopulmonary bypass, 15 minutes after cardiopulmonary bypass and the end of surgery; central venous oxygen saturation (ScvO2) after aortic unclamping were lower, the rate of using vasopressors and inotropes during and after surgery, the amount of ephedrine using during surgery were higher than group S with p<0.05.