Focal Segmental Glomerulosclerosis By Frank O'Brien, MD, Washington University in St Louis Reviewed / Revised Jun 2023 View Patient Education Symptoms and Signs Diagnosis Treatment Prognosis Key Points Topic Resources Body Surface Area (Du Bois... Focal Segmental Glomerulosclerosi... Focal Segmental Glomerulosclerosi... Focal Segmental Glomerulosclerosi... Focal Segmental Glomerulosclerosi... Focal Segmental Glomerulosclerosi... Collapsing Glomerulopathy Overview of Focal Segmental... Focal segmental glomerulosclerosis is scattered (segmental) mesangial sclerosis that begins in some but not all (focal) glomeruli and eventually involves all glomeruli.