Result: There was a significant decrease in serum zinc concentration of erythrodermic psoriasis group (0.617 ± 0.112mg / l) compared to the control group (0.847 ± 0.148mg / l), p<0.001. Conversely, the mean serum copper concentration of erythrodermic psoriasis patients (1.246 ± 0.274mg / l) were significantly higher than in control group (1.1 ± 0.32mg / l), p<0.05.