Stomatocytosis and Anemia Caused by Hypophosphatemia By Evan M Braunstein, MD, PhD, Johns Hopkins University School of Medicine Reviewed / Revised Jun 2022 | Modified Sep 2022 View Patient Education Stomatocytosis (red blood cells with a transverse slit or stoma across the center) and hypophosphatemia cause red blood cell membrane abnormalities that can result in hemolytic anemia.