Subject and method: 35 in-patients with psoriasis vulgaris treated at Department of Allergic Dermatology - 108 Military Central Hospital from May 2015 to May 2018 quantified concentration of cytokines IL-2, IL-4, IL-6, IL - 8, IL-10, IL-17, INF-α, TNF-α and GM - CSF in serum before and after treatment with UVB-311nm projection combined with low doses of MTX.