Severe acute pancreatitis and complications Treatment of severe acute pancreatitis and complications includes Intensive care unit (ICU) care Enteral nutrition preferred over parenteral nutrition Antibiotics for extrapancreatic infections and infected necrosis Necrosectomy (removal of necrotic tissue) for infected necrosis Endoscopic retrograde cholangiopancreatography (ERCP) for acute pancreatitis and concurrent acute cholangitis Drainage of pseudocysts The management of patients with severe acute pancreatitis and its complications should be individualized using a multidisciplinary approach including therapeutic endoscopists, interventional radiologists, and a surgeon.