Laryngoscope 125 (9): 2093 - 2098, 2015. doi: 10.1002 / lary.25338 Treatment of Laryngeal Cancer Early-stage (T1 and T2): Surgery or radiation therapy Moderately advanced (T3): Radiation therapy and sometimes chemotherapy Advanced (T4): Surgery (often followed by radiation therapy and sometimes chemotherapy) or sometimes chemotherapy and radiation therapy Early-stage glottic carcinoma is treated with laser excision, radiation therapy, or occasionally open laryngeal surgery.