Conclusion: The rate of surgical site infection at Quyhoa National Leprosy - Dermatology Hospital in 2017 - 2018 was 1.9%; Bacteria causing surgical site infections included Staphylococcus aureus, Pseudomonas aeruginosa, E coli, Coagulase Negative Staphylococcus and Enterobacter sp; Factors related to surgical site infection included patients with comorbidities, ASA class ≥2, 100% antibiotic use in postoperative patients.