Tetanus (Lockjaw) By Larry M Bush, MD, FACP, Charles E Schmidt College of Medicine, Florida Atlantic University; Maria T Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center Reviewed / Revised Jun 2023 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Treatment Prognosis Prevention Key Points Topic Resources Neonatal Tetanus Tetanus Prophylaxis in Routine... Tetanus is acute poisoning resulting from a neurotoxin produced by Clostridium tetani.