At the time of newly diagnosed type 2 diabetes insulin and C-peptide levels in diabetic group were higher than control group with statistical significance (p <0.001), insulin resistance increased 93.62% and 98.7%; beta-cell function reduces 51.91% and 57.52%, insulin sesitivity decreased 36.32 và 44.79%; insulin resistance and beta cell function reducing patient rate 68.3%, 76.9% and 84.7% 82.2% for calculating insulin and C-peptid.