For neonates born at ≥ 35 weeks gestation, phototherapy is an option when unconjugated bilirubin is > 12 mg / dL (> 205.2 micromol / L) and may be indicated when unconjugated bilirubin is > 15 mg / dL (257 micromol / L) at 25 to 48 hours, 18 mg / dL (308 micromol / L) at 49 to 72 hours, and 20 mg / dL (342 micromol / L) at > 72 hours (see Figure: Risk of hyperbilirubinemia in neonates).