Objectives: To determine the correlation between white blood cell count, hematocrit, platelet count, prothrombin time (PT), partial thromboplastin time (APTT), and fibrinogen level at the beginning of shock with reshock of Dengue shock syndrome (DSS). Material and method: case - control study. We analyzed the white blood cell count, hematocrit, platelet count, PT, APTT and fibrinogen level at the beginning of DSS of 110 children in re-shock group and 220 children in non-reshock group at the pediatric department of An Giang hospital. Results: the mean hematocrit at the beginning of shock was 46.8 ± 4.2 (%) in children with reshock group, significantly higher than the value 44.6±4.8 (%) in non-reshock group (p=0.016, OR =1.09).