The study results show that a honeysuckle flower dose of 0.72 g / kg / day, Oroxylum indicum dose of 1.2 g / kg / day together with honeysuckle flower combined with Oroxylum indicum with 1: 1 ratio had an acute antiinflammatory effect on the white rat on a mouse Leg Edema Model with carrageenin and the model causing mouse peritonitis.