The mean value of PlGF of the pre-eclampsia group was 38, 3 ± 10, the cut-off of the predictive value of PlGF was <35, 5 pg / ml, sensitivity: 66, 7%, specificity: 78, 4%. The group with PlGF value <35, 5 pg / ml had 1 6, 7 times greater risk of pre-eclampsia.