Results of monitoring respiratory function of patients over five years of asthma patients: the indexes (F) VC, FEV1, FEV1 / (F) VC, FEF25 - 75 and PEF were significantly increased comparing with the first visit; the respiratory indexes was strong increased in the first year and continued stable in the subsequent years, the value of respiratory parameters in male patients asthma tend to increase in female patients asthma while it tends to decrease.