One of these derivatives is mono-6-amino-6-deoxy derivatives of b-cyclodextrin, used for the enantioseparation of various anionic, amphoteric substance and amino acids by capillary electrophoresis (CE) such as glutamic acid, phenylalanine, threonine và valine,... Some beta-cyclodextrin derivatives as methyl-b-CD, methoxycarbonyl-b-CD and carboxymethy-β-cyclodextrin were successfully synthesized by our group. These derivatives were successfully applied for separation of some enantiomer drugs by CE, too.