The ulvan showed a significant cytotoxic activity against hepatocellular carcinoma HepG2 (IC50 = 31.81 ± 2.87µg / ml), human breast cancer MCF7 (IC50 = 26.45 ± 1.36µg / ml), and cervical cancer Hela (IC50 = 34.68 ± 3.84 µg / ml).