Insulin infusion to maintain plasma glucose between 140 and 180 mg / dL (7.8 and 10.0 mmol / L) Prevents adverse outcomes such as organ failure, Possibly enhances recovery from stroke, and Leads to improved survival in patients requiring prolonged (> 5 days) critical care Previously, glucose target levels were lower; however, it appears that the less stringent targets as described above may be sufficient to prevent adverse outcomes.