Annals of Blood Volume 6 March 2021 Symptoms and Signs of ITP Although often asymptomatic and identified only by a low platelet count on a routine assay, when present the symptoms and signs of immune thrombocytopenia are Petechiae Purpura and / or ecchymoses Mucosal bleeding Increased menstrual bleeding Gross gastrointestinal (GI) bleeding and hematuria are less common.