Hepatic Artery Occlusion By Whitney Jackson, MD, University of Colorado School of Medicine Reviewed / Revised Jan 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Causes of hepatic artery occlusion include thrombosis (eg, due to hypercoagulability disorders, severe arteriosclerosis, or vasculitis), emboli (eg, due to endocarditis, tumors, therapeutic embolization, or chemoembolization), iatrogenic causes (eg, ligation during surgery), vasculitis (via nonthrombotic mechanisms), structural arterial abnormalities (eg, hepatic artery aneurysm), eclampsia, cocaineuse, and sickle cell crisis.