Common risk factors include the following: Preexisting renal insufficiency (elevated creatinine) Diabetes mellitus, especially in patients with associated chronic kidney disease Hypertension Heart failure Multiple myeloma Age > 70 Use of other nephrotoxic drugs Dehydration In patients at risk of acute kidney injury after receiving iodinated intravascular contrast, the following measures should be considered: A reduced dose of contrast Use of an iso-osmolar agent Hydration Many hydration regimens exist; one example is IV administration of 0.9% normal saline at 1 mL / kg for 24 hours beginning a few hours before the procedure.