Symptomatic patients are given ceftazidime 30 mg / kg IV every 6 hours for 2 to 4 weeks (imipenem, meropenem, and piperacillin are acceptable substitutes), then oral antibiotics (one double-strength tablet of trimethoprim / sulfamethoxazole [TMP / SMX] 2 times a day or doxycycline 100 mg 2 times a day) for 3 to 6 months.