Studies about genes and metabolism have shown that: 1) Genes that have been shown to be strongly associated with type 2 diabetes is TCF7L2, type 1 diabetes is SLC30A8, (2) The genes have been shown to be associated with all markers of dyslipidemia, including total cholesterol, LDL, HDL, and cholesterol, triglycerides are PCSK9 and LDLR, (3) Some polymorphisms of the FTO gene can increase the risk of overweight and obesity in many subjects such as adults, children... BDNF gene affects the regulation of homeostasis. energy, as well as cravings and related neurological disturbances, (4) Genes that have been shown to be associated with common cancers include MSH2 gene for colorectal cancer, BRCA1, BRCA2 for breast cancer.