Results and conclusions: patients with reation to fresh frozen plasma infusion are most common (54/132 patients), followed by red blood cells (43/132 patients) and platelets (34/132 patients); reactions due to cryo infusion are rare (1/132 patients); the most common symptom of blood transfusion reactions was rash (52.3%), other expressions example shortness of breath (43.9%), fever (29.5), and chills (36.4%) were also appear in patients with blood transfusion responses; severe transfusion reactions accounted for 36.4%, less common than moderate level (63.6%); transfusion reactions mainly appear during the infusion time (68.2%), patients who have early expressions in the first 15 minutes after transfusion often have more severe symptoms.