A suspected >ign of constipation is accompanied by edema, prolonged jaundice, and delayed psychomotor development. Up to 86.5% had THS> 100 micro U / ml, 78.8% had an FT3 of 1 - 2 pg / ml, 73.1% had an 7T4 <0.4 ng / dl, 61.5% had anemia, 100% had delayed bone maturation on radiographs;