Main categories include Chemokines Hematopoietic colony-stimulating factors Interleukins (IL) Interferons (IFN-alpha, IFN-beta, IFN-gamma) Transforming growth factors (TGFs) Tumor necrosis factors (TNF-alpha, lymphotoxin-alpha, lymphotoxin-beta) Although lymphocyte interaction with a specific antigen triggers cytokine secretion, cytokines themselves are not antigen-specific; thus, they bridge innate and acquired immunity and generally influence the magnitude of inflammatory or immune responses.