Carbohydrate Intolerance By Zubair Malik, MD, Lewis Katz School of Medicine at Temple University Reviewed / Revised Mar 2023 View Patient Education Pathophysiology Etiology Symptoms and Signs Diagnosis Treatment Key Points Topic Resources Overview of Lactose Intolerance Carbohydrate intolerance is the inability to digest certain carbohydrates due to a lack of one or more intestinal enzymes.