Options include Vaginal prostaglandin E2 (dinoprostone) suppositories Vaginal and buccal misoprostol tablets IM injections of prostaglandin F2-alpha (dinoprost tromethamine) The typical dose of misoprostol is 600 to 800 mcg vaginally, followed by 400 mcg buccally every 3 hours for up to 5 doses.