Plasma Membrane Proteins By Jennifer Le, PharmD, MAS, BCPS-ID, FIDSA, FCCP, FCSHP, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego Reviewed / Revised Jun 2022 | Modified Sep 2022 View Patient Education Plasma membrane transporters affect pharmacologic activity of drugs by mediating their absorption, distribution, metabolism, and excretion (1).