Systemic Cancer Therapy By Robert Peter Gale, MD, PhD, DSC (hc), Imperial College London Reviewed / Revised Aug 2022 | Modified Sep 2022 View Patient Education Chemotherapy Endocrine Therapy Immune Therapy Differentiating Drugs Anti-Angiogenesis Drugs Targeted Therapies Gene Therapy Oncolytic Viruses Adjuvant and Neo-adjuvant Therapies More Information Systemic cancer therapy includes chemotherapy (ie, conventional or cytotoxic chemotherapy), hormone therapy, targeted therapy, and immune therapy (see also Overview of Cancer Therapy).