These disorders include the following: Acute infection (eg, sepsis, malaria, meningitis, toxic shock syndrome) Drugs Neuroleptic malignant syndrome Serotonin syndrome Status epilepticus (interictal) Stroke Thyroid storm Laboratory testing includes complete blood count, prothrombin time, partial thromboplastin time, electrolytes, blood urea nitrogen, creatinine, calcium, creatine kinase (CK), and hepatic profile to evaluate organ function.