The following are evaluated: Sensation (using pinprick and temperature for small fibers; using vibration and proprioception tests for large fibers) Motor strength (noting whether motor weakness is proportional to the degree of atrophy) Deep tendon reflexes (noting type and distribution of reflex abnormalities) Cranial nerves Central and peripheral nerve function Autonomic function Physicians should suspect a peripheral nervous system disorder based on the pattern and type of neurologic deficits, especially if deficits are localized to particular nerve roots, spinal nerves, plexuses, specific peripheral nerves, or a combination.