Multivariate analysis of risk factors for AKI (continued) Variables OR 95% CI p CPB time ≥ 120 minutes 2.18 1.12 - 4.21 < 0.05 Aortic clamping time ≥ 60minutes 3.26 1.57 - 6.77 < 0.01 Frozen plasma infusion ≥ 2 units 1.14 0.41 - 3.21 > 0.05 Lowest body temperature <35oC 0.54 0.17 - 1.68 > 0.05 CVP ≥ 12 cmH2O 2.01 1.16 - 3.49 < 0.05 Low cardiac output syndrome 3.74 1.34 - 7.59 < 0.05 Mechanical ventilation > 24 hours 3.63 1.35 - 9.76 < 0.05 Arterial blood pH <7.35 0.48 0.24 - 0.97 > 0.05 Serum lactate ≥ 4 mmol / L 1.64 0.92 - 2.93 > 0.05 The intra and postoperative independent risk factors for AKI included CPB time ≥ 120 minutes, aortic clamping time ≥ 60 minutes low cardiac output syndrome, mechanical ventilation > 24 hours, and CVP ≥ 12 cmH2O,.