After treatment, the Ph + group: 5 patients both FISH and RT-PCR were negative, 2 patients with negative FISH, RT-PCR weak positive, 2 patients have not evaluated; Ph-groups: MRD (minimal residual disease) after the induction phase: 0, 003% - 1, 014% depending on the type of LAP (leukemic associated phenotyping); Three patients with MLL-AF4 + after treatment gave negative results for 2 cases.