The aim of this study was to identify the clinical characteristics of the polypoid lesions of the gallbladder and indications for surgery. Methods: Clinical data were retrospectively correlated with the histopathologic characteristics of polypoid lesions in 277 patients who had cholecystectomy. Results: There were 277 polypoid lesions (174 females, 103 males, the mean age: 42), including 226 inflammatory polyps, 4 adenomas, 4 with adenomatous hyperplasia, 5 with adenomyomatous hyperplasia, 7cholesterol polyp, 3 with metaplasia and 8 with normal epithelium.