Genotype GA increases the risk of lumbar spine osteoporosis by 1.99 times compared with GG genotype (95% CI: 1.31 - 3.06), the difference is statistically significant with p<0.005; Similarly, the A allele increases the risk of lumbar spine osteoporosis 1.63 times compared with the G allele (95% CI: 1.17 - 2.43) (p=0.005).