However, the advantages of this operation are still controversial because some clinical trials showed a longer operating and high re-operation rate of lapsroscopic surgery. Objective: To measure the effect and safety of laparoscopic surgical treatment in patients with a diagnosis of perforated peptic ulcers in relation to abdominal septic complications, surgical wound infection, extra - abdominal complication and hospital length of stay. Results: We conducted a descriptive, retrospective study with 99 cases of perforated peptic ulcers that were treated by laparoscopic surgery, including 88 males and 11 females.