Treatment of Amebiasis Initially, metronidazole, tinidazole, or sometimes nitazoxanide Iodoquinol, paromomycin, or diloxanide furoate subsequently for cyst eradication For gastrointestinal symptoms and extraintestinal amebiasis, one of the following is used: Oral metronidazole 500 to 750 mg 3 times a day in adults (12 to 17 mg / kg 3 times a day in children) for 7 to 10 days Tinidazole 2 g orally once / day in adults (50 mg / kg [maximum 2 g] orally once / day in children > 3 years) for 3 days for mild to moderate gastrointestinal symptoms, 5 days for severe gastrointestinal symptoms, and 3 to 5 days for amebic liver abscess Metronidazole and tinidazole should not be given to pregnant women.