NPHS1, NPHS2, WT1, LAMB2, PLCE1, LMX1B genes were known to be closely associated with congenital nephrotic syndrome, while NPHS1, NPHS2, WT1, LAMB2, PLCE1, TRPC6, ACTN4, ADCK4, COQ2, COQ6 were found related to pediatric primary nephrotic syndrome.