Unless other mechanisms coexist to compound their severity, anemia and other cytopenias are modest and asymptomatic (eg, platelet counts, 50 to 100 × 10 3 / mcL [50 to 100 × 10 9 / L]; white blood cell counts, 2500 to 4000 / mcL [2.5 to 4 × 10 9 / L] with normal white cell differential count).