However, the actual efficacy of sublingual Misoprostol compared with Oxytocin infusion still remains unsettled Objectives and Methods: A prospective randomized controlled study comparing sublingual Misoprostol and Oxytocin infusion for term pregnancies with premature rupture of membranes. Results: When investigating 219 cases, we found that Bishop's score increased ≥3 points after 12 hours of induction in 90% (197/219) of cases.