Doses for cefotaxime are Children: 150 to 200 mg / kg / day IV in 3 to 4 divided doses (eg, 50 mg 3 to 4 times a day) Adults: 2 g IV every 8 hours Doses for ceftriaxone are Children: 50 to 75 mg / kg / day IV (2 g maximum) once a day Adults: 2 g IV once a day Clinicians should remember that concomitant anaplasmosis or babesiosis is possible in patients with severe disease.