Relapse is more likely in patients who have had any of the following: A seizure disorder since childhood Need for > 1 drug to be seizure-free Previous seizures while taking an antiseizure drug Focal-onset or myoclonic seizures Underlying static (nonprogressive) encephalopathy Abnormal electroencephalogram (EEG) results within the last year Structural lesions (seen on imaging studies) Of patients who relapse, about 60% do so within 1 year, and 80% within 2 years.