Polycystic Ovary Syndrome (PCOS) (Hyperandrogenic Chronic Anovulation; Stein-Leventhal Syndrome) By JoAnn V Pinkerton, MD, University of Virginia Health System Reviewed / Revised Jan 2023 View Patient Education Symptoms and Signs Diagnosis Treatment Key Points More Information Topic Resources Polycystic Ovary Syndrome... Acanthosis Nigricans in Polycysti... Polycystic ovary syndrome is a clinical syndrome typically characterized by anovulation or oligo-ovulation, signs of androgen excess (eg, hirsutism, acne), and multiple ovarian cysts in the ovaries.