Table Proton Pump Inhibitors Medication Most Conditions, Including Gastritis, GERD, and Uncomplicated Duodenal Ulcers Gastric Ulcers and Complicated Duodenal Ulcers Esomeprazole 40 mg once a day 40 mg 2 times a day Lansoprazole 30 mg once a day Pediatric dosages: < 10 kg: 7.5 mg once a day 10 - 20 kg: 15 mg once a day ≥ 20 kg: 30 mg once a day * 30 mg 2 times a day — Omeprazole 20 mg once a day Pediatric dosage: 1 mg / kg / day in a single dose or divided 2 times a day * 40 mg once a day — Pantoprazole 40 mg once a day 40 mg 2 times a day Rabeprazole 20 mg once a day 20 mg 2 times a day * Representative dosages.