The UGT1A1 * 6 variant is believed to increase the risk of neutropenia and is closely related to the risk of severe diarrhea in Asian cancer patients. In this study, we used the direct sequencing method exon 1 fragment of UGT1A1 gene to determine the genotype and allele frequency of UGT1A1 * 6 in 96 individuals of healthy Kinh ethnic group.