Risk factors for type 2 diabetes include Age ≥ 35 Overweight or obesity Sedentary lifestyle Family history of type 2 diabetes mellitus History of impaired glucose regulation (prediabetes) Gestational diabetes mellitus or delivery of a baby > 4.1 kg Hypertension Dyslipidemia (high-density lipoprotein [HDL] cholesterol < 35 mg / dL [0.9 mmol / L] or triglyceride level > 250 mg / dL [2.8 mmol / L]) History of cardiovascular disease Polycystic ovary syndrome African, Hispanic, Asian American, or American Indian race or ethnicity Fatty liver disease HIV infection People ≥ age 35 and all adults with additional risk factors described above should be screened for diabetes with an FPG level, HbA1C, or a 2-hour value on a 75-g OGTT at least once every 3 years as long as plasma glucose measurements are normal and at least annually if results reveal impaired fasting glucose levels (see table Diagnostic Criteria for Diabetes Mellitus and Impaired Glucose Regulation).