This work is carried out to evaluate the feasibility of the thoracoscopic surgery in harvesting samples for diagnosis of pulmonary solitary nodules. Methods: Retrospective of large serries of cases. Results and comments: 25 patients in 4 years from july-2004 to july-2008, including 20 males v 5 females. Mean age: 59 ys with the oldest is 75 years old and the youngest is 24 years old.