If an initial bolus is desired but IV access is delayed, 0.2 to 0.25 mg epinephrine may also be given through an endotracheal tube (2 to 2.5 mL of a 0.1 mg / mL solution diluted to 5 to 10 mL with sterile water or saline); alternatively, a second IM dose of epinephrine may be given.