Factor associated with optic nerve damage was late hospital admission; Factors related to mortality were deep coma, pupils loss of light reflexes, hypotension, respiratory failure, alcoholism, pH ≤ 7.0, lactat > 3.65 mmol / L, creatinin ≥ 130 µmol / L, CK > 1000 UI / L, glucose > 7, 7 mmol / L and methanol concentration ≥ 93.96 mg/dL.