Patients > 5 years are given oral doses of 62.5 mg every 6 hours to 250 mg every 12 hours (250 to 500 mg / day in 2 to 4 doses) and slowly increased to a maximum of 250 mg every 6 hours to 750 mg every 12 hours (1000 to 1500 mg / day in 2 to 4 doses).