Results: 220 cases ischemic infarction (112 female and 108 male, mean age 60.71±11.91) due to large-artery 20% and small-artery 80%. Mean plasma homocysteine was 14, 4µmol / L versus 13µmol / L, there was not significantly different between large-artery, small-artery atherosclerosis (p=0.1).