THE EFFECTIVENESS OF INTRAVENOUS DRUG DOSE OF ALTEPLASE 0.6 MG / KG IN TREATMENT OF HYPER ACUTE ISCHEMIC ASSOCIATED WITH ATRIAL FIBRILLATION WITHIN 4.5 HOURS Purpose: to assess the effectiveness of intravenous drug dose of Alteplase 0.6 mg / kg in treatment of hyper acute ischemic within 4.5 hours associated with atrial fibrillation.