Paget Disease of Bone (Paget's Disease of Bone; Osteitis Deformans) By Julia F Charles, MD, PhD, Brigham and Women's Hospital Reviewed / Revised May 2023 View Patient Education Etiology Pathophysiology Symptoms and Signs Diagnosis Treatment Key Points Topic Resources Frontal Bossing in Paget... Bowing of the Tibia in Paget... X-Ray of the Skull in Paget... X-Ray of the Pelvis in Paget... Paget disease of bone is a chronic disorder of the adult skeleton in which bone turnover is accelerated in localized areas.