Overview of Leukemia By Ashkan Emadi, MD, PhD, University of Maryland; Jennie York Law, MD, University of Maryland, School of Medicine Reviewed / Revised Jun 2022 | Modified Sep 2022 View Patient Education Classification of Leukemia Risk Factors for Leukemia More Information Topic Resources Findings at Diagnosis in... Leukemia is a malignant condition involving the excess production of immature or abnormal leukocytes, which eventually suppresses the production of normal blood cells and results in symptoms related to cytopenias.