Results: male (74%) and female (26%), most of the time appeared symptoms is less than 5 years (62.2%), heartburn (85.9%), regurgitation (71.8%), heartburn and regurgitation frequency of reflux daily high percentage (31.9%), sore throat, hoarseness (76.8%), sleep disorders (76.8%) and 68.1% are coughing, dyspnea was 36.2%.