Testicular Cancer By Thenappan Chandrasekar, MD, Thomas Jefferson University Reviewed / Revised Jan 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Prognosis Treatment Key Points Topic Resources Testicular Cancer AJCC / TNM * Staging of Testicular... TNM and Serum Marker Definitions... Testicular cancer begins as a scrotal mass, which is usually not painful.