Table Acquired immune deficiency syndrome (AIDS) AIDS is defined as HIV infection with one or more of the following: One or more AIDS-defining illnesses (1) A CD4+ T lymphocyte (helper cell) count of < 200 / mcL A CD4+ cell percentage of ≤ 14% of the total lymphocyte count AIDS-defining illnesses include Serious opportunistic infections Certain cancers (eg, Kaposi sarcoma, non-Hodgkin lymphoma) to which defective cell-mediated immunity predisposes Neurologic dysfunction Wasting syndrome AIDS-Defining Illnesses Bacterial infections, multiple or recurrent * Candidiasis of bronchi, trachea, or lungs Candidiasis of esophagus Cervical cancer, invasive† Coccidioidomycosis, disseminated or extrapulmonary Cryptococcosis, extrapulmonary Cryptosporidiosis, chronic intestinal (lasting > 1 month) Cytomegalovirus disease (other than liver, spleen, or lymph nodes), onset at age > 1 month Cytomegalovirus retinitis (with loss of vision) Encephalopathy attributed to HIV Herpes simplex: chronic ulcers (lasting > 1 month) or bronchitis, pneumonitis, or esophagitis (onset at age > 1 month) Histoplasmosis, disseminated or extrapulmonary Isosporiasis (cystoisosporiasis), chronic intestinal (lasting > 1 month) Kaposi sarcoma Lymphoma, Burkitt (or equivalent term) Lymphoma, immunoblastic (or equivalent term) Lymphoma, primary, of brain Mycobacterium avium complex (MAC) or Mycobacterium kansasii, disseminated or extrapulmonary Mycobacterium tuberculosis of any site, pulmonary, disseminated, or extrapulmonary Mycobacterium, other species or unidentified species, disseminated or extrapulmonary Pneumocystis jirovecii (previously known as Pneumocystis carinii) pneumonia Pneumonia, recurrent† Progressive multifocal leukoencephalopathy Salmonella septicemia (nontyphoid), recurrent Toxoplasmosis of brain, onset at age > 1 month Wasting syndrome attributed to HIV See also Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report (MMWR): Revised Surveillance Case Definition for HIV Infection, United States, 2014.