Our results showed that group A's mean age was lower than that of group B, 92.4% of group A had HBV-DNA levels above 105 copies / ml, serum HBV-DNA levels decreased by a mean of 2log10 in group B. 66.7% of group B had HBV-DNA levels below 105 copies / ml; therefore, more studies to find why the inflammatory status still progressed is to be designed.