Statins are recommended as preventive therapy in 4 groups of patients (1), comprised of those with any of the following: Clinical atherosclerotic cardiovascular disease LDL cholesterol ≥ 190 mg / dL (≥ 4.92 mmol / L) Age 40 to 75 years, with diabetes and LDL cholesterol 70 to 189 mg / dL (1.81 to 4.90 mmol / L) Age 40 to 75 years, with LDL cholesterol 70 to 189 mg / dL, and estimated 10-year risk of arteriosclerotic cardiovascular disease ≥ 7.5% There is also support for the use of statins in patients with other risk factors, including family history of premature arteriosclerotic cardiovascular disease (ie, age of onset < 55 in male 1st degree relative, or < 65 in female 1st degree relative), high-sensitivity C-reactive protein ≥ 2 mg / L (19.05 nmol / L), coronary artery calcium score ≥ 300 Agatston units (or ≥ 75th percentile for the patient's demographic), ankle-brachial blood pressure index < 0.9, or chronic kidney disease not treated with dialysis or kidney transplantation.