Mice in all groups were taken blood before the test, after treated the drug for 30 days to do the tests for blood formula (number of red blood cells (million / mm3), the number of white blood cells (thousand / mm3), hemoglobin (g / L), hematocrit (%), and determination of liver function parameters (AST, ALT), renal function parameters (creatinine, urea) and blood glucose, lipid.