Objectives and and methods: We conducted a descriptive study in order to assess the disease progression, changes in CD4 cell counts of 153 adult HIV-infected persons treated with initial antiretroviral regimens over a 12-month period at the Hospital for Tropical Diseases between October 2005 and October 2007.Results: Incidence of any opportunistic infectiosllnesses (OI) decreased from 22.9% in the first 3 months after starting antiretroviral treatment to 9.5% in the next 3 months and 0.7% between 6 and 12 months.