Some drugs that have been shown to increase driving risk include Antihistamines, benzodiazepines, opioids, anticholinergics, hypnotics, antihypertensives, and tricyclic antidepressants, which can cause drowsiness, hypotension, or arrhythmias Antiparkinsonian dopamine agonists (eg, pramipexole, ropinirole), which can occasionally cause acute sleep attacks Antiemetics (eg, prochlorperazine) and muscle relaxants (eg, cyclobenzaprine), which can alter sensory perception Antiseizure drugs, which can cause sedation (alternatives may need to be considered) When starting a new drug that could affect visual, physical, or cognitive function, patients should refrain from driving for several days (depending on the time required to reach a steady state) to be sure no adverse effects occur.