Comparison of cytokine serum levels in the study group before and after treatment (n = 35) Cytokine (pg / ml) study group (n=35) control group (n=44) p (Mann - whitney test) IL-2 (X±SD) 2, 00 ± 0, 00 2, 00 ± 0, 00 > 0, 05 IL-6 (X±SD) 16, 22 ± 40, 01 3, 50 ± 0, 00 < 0, 001 IL-8 (X±SD) 609, 80 ± 902, 12 2, 20 ± 5, 13 < 0, 001 IL-10 (X±SD) 3, 40 ± 2, 99 0, 73 ± 0, 50 < 0, 001 IL-12 (X±SD) 1, 46 ± 0, 60 0, 90 ± 0, 44 < 0, 001 IL-17 (X±SD) 0, 65 ± 0, 84 0, 69 ± 0, 00 < 0, 001 TNF-α (X±SD) 3, 55 ± 1, 39 0, 34 ± 0, 82 < 0, 001 IFN - (X±SD) 1, 43 ± 0, 53 0, 71 ± 0, 39 < 0, 001 14 Conclusion: Before and after treatment, the concentration of cytokines did not change statistically (p>0.05).