- Side effects in subclinical features: Table 3.22: Cases with abnormal blood test (MTX+MET) (n = 33) Before treatment n (%) 1 month n (%) 2 month n (%) 3 months n (%) Hemoglobin (12 - 16g / dL) below 2g / dL 0 0 0 0 Number of WBC (5 - 10 x 109/L) Below 5 x 109/L 0 0 0 0 33 Below 3 x 109/L 0 0 0 0 Number of RBC (4 - 6, 13M / µL) Below 4M / µL 0 4 (12, 1) 4 (12, 1) 3 (9, 1) Number of platelet (140 - 440 x 103/L) Below 140 x 103/L 0 0 0 0 Below 100 x 103/L 0 0 0 0 Note: The results showed that after 3 months, there were 3 patients (9.1%) with RBC below < 4M/µL.