Treatment of Hypertension in Pregnancy For mild hypertension, conservative measures followed by antihypertensives if needed Methyldopa, beta-blockers, or calcium channel blockers tried first Avoidance of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), and aldosterone antagonists For moderate or severe hypertension, antihypertensive therapy, close monitoring, and, if condition worsens, possibly termination of pregnancy or delivery, depending on gestational age Recommendations for chronic and gestational hypertension are similar and depend on severity.