The result of research will be the firm bases for the next steps in health improvement. Objective: To determine the proportion of people processing food directly in household in My An commune, Mang Thit district, Vinh Long province in 2008 have right knowledge, practice on hygiene and safety food and the association between age, ethnic, gender, level of education, information about hygiene and safety food propagandized, household economic status and right knowledge, practice on hygiene and safety food.