For patients suspected of having COVID-19, the American Heart Association released interim guidance for basic and advanced life support (1, 2), which advises the following: Use of personal protective equipment (PPE) appropriate for aerosol-generating procedures (respiratory protection against airborne and droplet particles, eye protection, gloves) for all people present in the treatment area during CPR or other advanced procedures (eg, intubation, chest decompression) Preference for endotracheal intubation or supraglottic airway placement over bag-valve-mask ventilation if this can be done without interrupting compressions Use of a HEPA (high efficiency particulate air [filter]) viral filter on bag-valve devices or ventilator exhalation circuits Use of a mechanical chest compression device if available This guidance aims to decrease the risk to the health care workers providing care during cardiac arrest.