Joint Tumors By Michael J Joyce, MD, Cleveland Clinic Lerner School of Medicine at Case Western Reserve University; David M Joyce, MD, Moffitt Cancer Center Reviewed / Revised Jul 2022 | Modified Sep 2022 View Patient Education Topic Resources Synovial Chondromatosis Tenosynovial Giant Cell Tumor Tumors rarely affect joints, unless by direct extension of an adjacent bone or soft tissue tumor.