After 2nd infusion, CI increased from 3.84 ± 1.78l / min / m2 to 4.61 ± 1.24l / min / m2; GEDVI increased from 767.5 ± 245.12ml / m2 to 809.65 ± 216.06ml / m2; SVV decreased from 14.12 ± 5.43% to 12.67 ± 7.35%.