Peripheral eosinophilia is characterized as Mild: 500 to 1500 / mcL (0.5 to 1.5 × 10 9 / L) Moderate: 1500 to 5000 / mcL (1.5 to 5 × 10 9 / L) Severe: > 5000 / mcL (> 5 × 10 9 / L) Diurnal levels vary inversely with plasma cortisol levels; the peak occurs at night and the trough in the morning.