Subjects and methods: A descriptive retrospective combined prospective study on 32 patients with stage II, III middle - lower third esophageal cancer receiving preoperative concurrent chemoradiotherapy with weekly Paclitaxel / Carboplatin regimen (the dose of Paclitaxel was 50mg / m2 in combination with Carrboplatin administered the dose at AUC 2) and radiation with a dose of 41.4Gy/23Fr followed by surgery.