Diagnosis of Hepatic Fibrosis Clinical evaluation Sometimes blood tests and / or noninvasive imaging tests Sometimes liver biopsy Hepatic fibrosis is suspected if patients have known chronic liver disease (eg, chronic viral hepatitis C [HCV] or chronic hepatitis B [HBV], alcoholic liver disease) or if results of liver blood tests are abnormal; in such cases, tests are done to check for fibrosis and, if fibrosis is present, to determine its severity (stage).