IV midazolam: Titrate to patient response (sedation) as follows: Initial dose: 0.5 to 2 mg IV over ≥ 2 minutes Subsequent doses (after 2 to 5 minutes): 0.5 to 2 mg IV doses over ≥ 2 minutes Maximum dose: 2.5 mg / dose and 5 mg cumulative IV dose (1.5 mg and 3.5 mg for patients ≥ 60 years of age) Intramuscular midazolam: 5 mg IM (0.1 to 0.15 mg / kg in children).