Plasma presepsin concentration in patients with severe infections and septic shock Plasma presepsin concentration in the study group: The highest presepsin plasma concentration in the study group at the time of diagnosis was 420 pg / mL (quart ile 227.3 - 722.8 pg / ml) and decreased. gradually at T1 345.1 pg / mL (quart ile 194.9 - 591.1 pg / ml), and T7 was 279.4 pg / mL (quartile 180.6 - 568.3 pg / ml), there was a difference in presepsin concentration at T7 compared to T0 (p <0.05) (Table 3.10).