Background: Home remedies of Ly Cuu with Kim Su capsules (Herba epimedii, Allium tuberosum, Polyscias fruticosa and Ginkgo biloba) have been used for years to treat depression, fatigue, spermatorhea, back pain, knee fatigue, and urinary frequency. In this study, we have developed the quality specifications of Kim Su capsules (Herba epimedii, Allium tuberosum, Polyscias fruticosa and Ginkgo biloba) to contribute to the control of prescription.