(2) determine the ADC threshold value to differentiate benign from malignant lesions. Materials and methods: 182 lesions of 135 patients of those 5 focal hepatic lesion types were examined with isotropy diffusion weighted MR sequence. ADCs were measured and compared to define the ADC threshold value to differentiate benign from malignant lesions. Results: The mean ADCs of hepatic cysts, hemangiomas, hepaticellular carcinomas, cholangiocarcinomas and metastasis were 2.68 x 10 - 3 mm2 / sec ± 0.298, 1.78 x 10 - 3 mm2 / sec ± 0.337, 1.00 x 10 - 3 mm2 / sec ± 0.224, 1.1 x 10 - 3 mm2 / sec ± 0.163 and 1.08 x 10 - 3 mm2 / sec ± 0.293 respectively.