In group of treatment based on antibiogram, the eradication success rate in children with bismuth was statistical significantly higher than those without bismuth (PPIs - standard-dose amoxicillin - metronidazole - bismuth 75% vs PPIs - standard-dose amoxicillin - metronidazole 55%, PPIs-high-dose amoxicillin - metronidazole - bismuth86% vs PPIs - high-dose amoxicillin - metronidazole 48%) (p=0.04).