After taking Ivabradine 5mg twice daily, at 1 month follow-up, 23/24 of patients (95.8%) reached target heart rate of under 90 bpm with significant reduction of HR during 24h (76.8 ± 7.9 bpm vs 94.8 ± 4.9 bpm, p < 0.001); at rest (79.1 ± 12.1 bpm vs 106.1 ± 7.5 bpm, p < 0.001); on standing (87.3 ± 14.3 bpm vs 122.3 ± 9.8 bpm, p < 0.001).