Disorders best characterized are Familial Mediterranean fever Hyper-IgD syndrome Tumor necrosis factor (TNF) receptor-associated periodic syndrome Other disorders include The hereditary cryopyrin-associated periodic syndromes (cryopyrinopathies): Familial cold autoinflammatory syndrome, Muckle-Wells syndrome, and neonatal-onset multisystem inflammatory disease (NOMID) PAPA (pyogenic arthritis, pyoderma gangrenosum, and acne) syndrome PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) syndrome, which may not be hereditary