Background and Objectives: Andrographis paniculata has been reported as a potential drug, which possess anti-inflammatory, antibacterial, hypoglycemia, anti-cancer... Phytoconstituents such as four diterpenlactone compounds: andrographolid, neoandrographolid, dehydroandrographolid and angrograpanin have been extracted and isolated from Andrographis paniculata in Viet Nam.