Modern facilities and technical support in diagnosis as well as treatment such as laparoscopic surgery, CUSA, harmonic scalpel, intraoperative ultrasound, epidural anesthesia, central venous pressure monitoring, and invasive arterial blood pressure monitoring improve the quality of diagnosis and treatment for this disease. Objectives: Description of clinical features and anesthetic techniques in liver resection for HCC Subjects and methods: Prospective descriptive study of patients having liver resection for the treatment of HCC at the University Medical Centre, Ho Chi Minh City from Jan 2009 to Jan 2010.Results: Patients comprised of 76 men and 21 women, aged 54.9 ± 11.4 yr (range 23 - 80).