Melanoma (Malignant Melanoma) By Gregory L Wells, MD, Ada West Dermatology and Dermatopathology Reviewed / Revised Sep 2022 View Patient Education Risk Factors Classification Diagnosis Prognosis Treatment Prevention Key Points More Information Topic Resources Malignant Melanoma (Non-Sun-Expos... Congenital Melanocytic Nevus Dysplastic Nevi Melanoma (Superficial Spreading) Nodular Melanoma Lentigo Maligna Melanoma... Lentigo Maligna Melanoma Acral-Lentiginous Melanoma Acral-Lentiginous Melanoma... Amelanotic Melanoma Staging of Localized Melanoma... Malignant melanoma arises from melanocytes in a pigmented area (eg, skin, mucous membranes, eyes, or central nervous system).