Drug Treatment of Diabetes Mellitus By Erika F Brutsaert, MD, New York Medical College Reviewed / Revised Sep 2022 View Patient Education Insulin Oral Antihyperglycemic Drugs Injectable Antihyperglycemic Drugs Adjunctive Drug Therapy for Diabetes More Information Topic Resources Onset, Peak, and Duration... Characteristics of Oral Antihyper... Characteristics of Injectable... General treatment of diabetes mellitus for all patients involves lifestyle changes, including diet and exercise.