Conclusion: The optimal formula has been developed including: Salbutamol sulfate 666.67mg; PVA 2.01%; Glucose 1%; PG 0.0201%; Sodium lauryl sulfate 0.85%; Distilled water 20ml; Ethanol 70% added to 100 ml; 15 ml were cast into a 5 cm diameter petri dish; films with a diameter of 10 mm.