Results of of treatment by Cyclosporin A for severe psoriasis vulgaris patients Our study results in table 3.22 and table 3.23 show that, after 5 weeks and 10 weeks of treating 35 patients with severe VNTT with cyclosporine A dose of 2.5 - 3mg / kg / day, combined with Cetaphil moisturizer, PASI decreased after 5 weeks from 25, 38±4, 20 to 9.29 ± 22 3.20 and decreased significantly after 10 weeks from 25.38±4.20 to 5.50±3.74, the change was statistically significant with p<0.001.