In order to contribute training system of thinking and aware of leprosy, study was carried out to survey knowledge and attitute of of leprosy of junior high school pupils in Lien Huong, Tuy Phong, Binh Thuan. Aims: To identify propotion of knowledge and attitute of leprosy of junior high school pupils in Lien Huong, Tuy Phong, Binh Thuan and identify relationship between knowledge and attitute with sex, grade and race of pupils. Methods: The cross - secsional study was carried out among the pupils of junior high school pupils in Lien Huong, Tuy Phong, Binh Thuan in April, 2008.