Ebstein Anomaly (Ebstein's Anomaly) By Lee B Beerman, MD, Children's Hospital of Pittsburgh of the University of Pittsburgh School of Medicine Reviewed / Revised Apr 2023 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Treatment More Information Ebstein anomaly is a rare congenital cardiac defect that consists of variable apical displacement from the annulus and dysplasia of the septal and inferior leaflets of the tricuspid valve.