COVID-Related Neuropsychiatric Manifestations By Juebin Huang, MD, PhD, Department of Neurology, University of Mississippi Medical Center Reviewed / Revised Oct 2021 | Modified Nov 2021 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Prognosis Treatment Key Points COVID-19 is primarily an acute respiratory syndrome, but it can also cause dysfunction of multiple organs and body systems, including the brain.