Infertility can be caused by the following: Sperm disorders (≥ 35% of couples) Ovulatory dysfunction or (less frequently) decreased ovarian reserve (about 20%) Tubal dysfunction and pelvic abnormalities (about 30%) Abnormal cervical mucus (≤ 5%) Unidentified factors (about 10%) Inability to conceive often leads to feelings of anxiety, sadness, frustration, anger, guilt, resentment, and inadequacy.