Elevated D-dimers may also predict adverse outcomes such as mechanical ventilation, ICU admission, and disease severity in patients with COVID-19.5, 36 - 38 Studies have also shown high bleeding complications in COVID-19 patients with elevated D-dimer levels (>2500 ng / mL), complicating anticoagulation strategies for these patients.39, 40 2 IMAGING CONSIDERATIONS Chest radiograph Chest radiographs (CXR) lack accuracy in diagnosing PE and are typically reserved for diagnosing alternative conditions, such as pulmonary edema, pneumonia, and pneumothorax that could simulate PE.