There are only two genotype of HBV: genotype B and genotype C Totally there are 16 cases (22.2%) mutations with following established proportions and types M204I (37, 50%), M204V (12, 50%), L180M+M204I (12.50%), L180+M204V (18.75%) and M204V+L180M+V173L (6.25%), A181T (12.50%).