Results: There are 163 patients in our study include 127 (80%) patients who have at least one complication: constipation 47, 2%, hyperglycemia 21, 5%, intracranial hypertension 22, 1%, cardiovascular complication 30, 1%, pneumonia complication 35%, seizure 6, 7%, gastrointestinal bleeding 7, 4%, urinary retention 23, 9%, urinary tract infection 9, 2%, skin ulcer 15, 3% and hyponatremia 9, 8%.