Symptoms and Signs of Platelet Disorders Platelet disorders result in a typical pattern of bleeding: Multiple petechiae in the skin (typically most evident on the lower legs) Scattered small ecchymoses at sites of minor trauma or venipuncture sites Mucosal bleeding (oropharyngeal, nasal, gastrointestinal, genitourinary) Excessive bleeding after surgery Extensive menstrual bleeding Manifestations of Platelet Disorders Petechiae in Immune Thrombocytopenia (ITP) By permission of the publisher.