Results: This study revealed five common β-globin gene mutations, including HbE (47.5%), cd 17 (A>T) (35%), cd 41/42 (- TTCT) (12.5%), - 28 (A>G) (2.5%) và cd 71/72 (+A) (2.5%); The results of the MARMSPCR were completely in concordance with that of the Sanger sequencing.