Table Treatment of Allergic Conjunctivitis Symptomatic measures Topical antihistamines, nonsteroidal anti-inflammatory drugs (NSAIDs), mast cell stabilizers, or a combination Topical corticosteroids or cyclosporine for recalcitrant cases Sometimes, oral antihistamines Avoidance of known allergens and use of cold compresses and tear supplements can reduce symptoms of allergic conjunctivitis; antigen desensitization is occasionally helpful.