In our study, the biggest difference of RE - SE at the awake level was the time point before anesthesia (group N0.5 was 9.84 ± 1.8, group N1 was 9.3 ± 2.1) after endotracheal extubation (Group N0.5 is 8.4 ± 1.6, Group N1 is 8.3 ± 2.0).