Results: Total 2500 patients, 1631 patients (65.24%) had pain, average age: 54.58 ± 15.23, 916 male patients (56.2%), 715 female patients (43.8%), mild pain: 37 patients (2.3%), moderate pain: 776 patients (47.6%), severe pain: 818 patients (50.2%), 298 patients (18.27%) had both receptive pain and neuropathic pain, 170 patients (10.4%) had good pain control with treatment level 1, 984 patients (60.3%) had good pain control with treatment level 2, the common dose of Tramadol injection: 300mg / day (80.9%), 477 patients (29.3%) had good pain control with treatment level 3, 216 patients (about 52% patients with severe pain) had good pain control with Morphin oral (average dose: 95.76 ± 39.64 mg/24 hours), average dose of Morphin subcutaneous injection: 38 ± 14.98 mg/24 hours, average dose of Morphin continuous subcutaneous infusion: 58.70 ± 23.60 mg/24 hours, the common dose of fentanyl patch: 25 mcg / h.