Single-Gene Defects By Quasar S Padiath, MBBS, PhD, University of Pittsburgh Reviewed / Revised Jun 2023 View Patient Education Autosomal Dominant Autosomal Recessive X-Linked Dominant X-Linked Recessive Topic Resources Autosomal dominant inheritance Autosomal recessive inheritance X-linked dominant inheritance X-linked recessive inheritance Examples of Genetic Disorders... Genetic disorders determined by a single gene (Mendelian disorders) are easiest to analyze and the most well understood.