The evaluation of XO enzyme inhibition shows that EtOAc fraction extract had the strongest XO enzyme inhibitory activity (IC50: 29.65 ± 0.93 μg / mL), followed by n-BuOH fraction (IC50: 37.22 ± 1.23 μg / mL), EtOH fraction (IC50: 52.13 ± 0.56 μg / mL), and the lowest was n-hexane fraction (IC50: 80.12 ± 0.21 μg/mL).