5 years with some first key points Results: During 3, 5 years with 500 cases have confirmed NPC show that the female patient is rising (2: 1, 12), and ENT patient have more and more younger than before (average 49 year old), most of them came to see Docter was late or too late (> 92%), 1 case was diagnosed 4 years after first symptom appear, and 1 case was recurrent just one month had finished radiotherapy. Conclusion: Appropriate endoscopic nasopharynx is a minimally invasive, safe, and more convention for biopsy with encouraging short-term outcome and saves NPC patients life who suffering or has just contaminated this horrible disease.