Comparison of the prescribing between the pre-using group and the post-using group showed that the rate of bacterial culture increased from 70% to 77%, in which the rate of culture indication before prescribing antibiotics increased from 14% to 45%, the initial antibiotic monotherapy regimen increased from 26% to 36%, the proportion of patients improved clinically after 72 hours increased from 64% to 89%, the rate of treatment failure at hospital discharge decreased from 12% to 6%.