Detailed fetal echocardiography is performed in high-risk cases, which could be a result of fetal (extracardiac anomalies, increased nuchal translucency, hydrops, or polyhydramnios), maternal (teratogen exposure, metabolic disorders, congenital heart defect, folic acid deficiency, or autoantibodies), or familial (sibling or father with congenital heart defect and Mendelian syndromes) factors.