Results: Survey of 24 hypertensive patients, divided 2 groups of patients using Telmisartan 40mg at bedtime or on awakening: 24-hour blood pressure stable, frequency of dippers 8.4%, reverse dippers rate 45.8% with using telmisartan on awakening and 20.8% with using telmisartan at bedtime; Blood pressure load diurnal: 3.9% and 10.2%, nocturnal: 25.5% and 30.2%; awake blood pressure soaring rate at 8.3% and 4.3%; the nocturnal mean of blood pressure: 84.0 ± 7.8 and 84.4 ± 10.3; diurnal and nocturnal systolic blood pressure difference: 1.5 ± 6.4% vs 4.0 ± 5.1%, p = 0.023, diurnal / nocturnal ratio of systolic blood pressure increased 2.4 ± 4.8 mmHg when using telmisartan at bedtime.