Definition: According to KDIGO (Kidney Diseases Improve Global Outcome) in 2012, diagnostic criteria for INS are as follows: edema, nephrotic-range proteinuria ≥ 50mg / kg/24 hours, serum albumin level ≤ 25 g / l (hypoalbuminemia), total serum protein level ≤ 56 g / l (hypoproteinemia), serum cholesterol level ≥ 5.5 mmol / l (or ≥ 220 mg%) (hypercholesterolemia).