J Invest Dermatol 115: 149 - 153, 2000. doi: 10.1046 / j.1523 - 1747.2000.00061.x Treatment of SJS and TEN Supportive care Cyclosporine Possibly corticosteroids, plasmapheresis, IV immune globulin (IVIG), or tumor necrosis factor (TNF) - alpha inhibitors Treatment is most successful when Stevens-Johnson syndrome and toxic epidermal necrolysis are recognized early and treated in an inpatient dermatologic or intensive care unit setting; treatment in a burn unit may be needed for severe disease.