Sexual Interest / Arousal Disorder By Allison Conn, MD, Baylor College of Medicine, Texas Children's Pavilion for Women; Kelly R Hodges, MD, Baylor College of Medicine, Texas Children's Pavilion for Women Reviewed / Revised Mar 2021 | Modified Sep 2022 View Patient Education Etiology Diagnosis Treatment Sexual interest / arousal disorder is characterized by absence of or a decrease in sexual interest, initiation of sexual activity, pleasure, thoughts, and fantasies; absence of responsive desire; and / or lack of subjective arousal or of physical genital response to sexual stimulation—nongenital, genital, or both.