Symptoms depend on the location of the clot, as in the following examples: Chest pain and shortness of breath: Possible PE Leg warmth, redness, and swelling: DVT Weakness / numbness of one side of the body, problems speaking, and problems with balance and walking: Possible ischemic stroke Abdominal pain: Possible mesenteric ischemia Most of the inherited disorders do not begin to cause an increased risk of clotting until young adulthood, although clots can form at any age.