Korsakoff Psychosis (Korsakoff Amnestic Syndrome; Korsakoff Psychosis) By Gerald F O'Malley, DO, Grand Strand Regional Medical Center; Rika O'Malley, MD, Grand Strand Medical Center Reviewed / Revised Dec 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Korsakoff psychosis is a late complication of persistent Wernicke encephalopathy and results in memory deficits, confusion, and behavioral changes.