4.3.2 Effects of antiviral drugs on some functions of organs Our research results are similar to other studies in the world: Pan and colleagues' research showed that ALT levels increased from 1.1 to 5 times and creatinine increased from 1.3 to 3 times of average values after TDF treatment; Zhang et al. (2014) also reported an increase in ALT of 1.3 to 4.5 times after LAM treatment for pregnant women and no case of flare was seen.