At internal department I of the general hospital of Dong Nai province, the authors examined over 44 Graves' patients, who were divided into two teams. The first team took Propranolol (24 patients), the second took Atenolol (20 patients) in order to compare their effect in the treatment of external appearance of Graves' disease. After a period research, the authors gave the remarks as follows: Atenolol was capable to lessen the frequeney of heart from Graves' disease faster than Propranolol.