Background: To determine the sensitivity, accuracy, positive predictive value and negative predictive value of ulltrasound in diagnosis of chronic pancreatitis and describe common lesions of chronic pancreatitis on ultrasound. Methods: study on 110 patients, the results of ultrasound compared with the "gold standard". Results: The study found that ultrasound can diagnose chronic pancreatitis with the sensibility was 89, 1%, specificity 96, 3%, positive predictive value 96, 1%, negative predictive value 96, 1%, Common image in chronic pancreatitis was parenchyma thick echo associated with calculi. Conclusion: Ultrasound plays an important role in screening patient with chronic pancreatitis.