Patients who are taking such drugs and urgently need linezolid may be treated if the benefit is thought to outweigh the risk and if they Promptly stop the proserotonergic drug Are carefully monitored for manifestations of serotonin syndrome for 2 weeks after stopping the drug (for fluoxetine, 5 weeks) or for 24 hours after the last linezolid dose Linezolid has not been studied in patients with carcinoid syndrome; it should be used only if patients are closely monitored for symptoms and signs of serotonin syndrome.