Lupus Nephritis By Frank O'Brien, MD, Washington University in St Louis Reviewed / Revised Jun 2023 View Patient Education Pathophysiology Symptoms and Signs Diagnosis Treatment Prognosis Key Points Topic Resources Lupus Nephritis—Mesangial... Lupus Nephritis—Focal (Class... Lupus Nephritis—Diffuse... Lupus Nephritis—Membranous... Classification of Lupus Nephritis Lupus nephritis is glomerulonephritis caused by systemic lupus erythematosus (SLE).