There are six factors are in shock fever, effective pressure ≤ 10 mm Hg, WBC > 9000, major bleeding, coagulopathy and disseminated intravascular coagulation associated with shock DHF heavy, with p = 0.011, respectively, p < 0.001, p < 0.001, p < 0.001, p = 0.001 and p < 0.001.