Red flags The following findings are of particular concern: Delayed passage of meconium (> 24 to 48 hours after birth) Hypotonia and poor suck (suggesting infant botulism) Abnormal gait and deep tendon reflexes (suggesting spinal cord involvement) Interpretation of findings A primary finding that suggests an organic cause in neonates is constipation from birth; those who have had a normal bowel movement are unlikely to have a significant structural disorder.