Causes of uterine rupture include Uterine overdistention (due to multifetal pregnancy, polyhydramnios, or fetal anomalies) External or internal fetal version Iatrogenic perforation Excessive use of uterotonics Failure to recognize labor dystocia with excessive uterine contractions against a lower uterine restriction ring If women who have had a prior cesarean delivery wish to try vaginal delivery, prostaglandins should not be used because they increase risk of uterine rupture.