Penile Cancer By Thenappan Chandrasekar, MD, Thomas Jefferson University Reviewed / Revised Jan 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Prevention Key Points Topic Resources Bowenoid Papulosis Bowen Disease of the Penis Most penile cancers are squamous cell carcinomas; they usually occur in uncircumcised men, particularly those with poor local hygiene.