22 Our study in the group with end-systolic left ventricular volume (ESV) of over 70 ml had markedly more severe dyssynchrony with a higher PSD (67.44 ± 14.03 and 42.9 ± 17.2; p <0.05) and higher HBW (218.64 ± 59.3 and 135.3 ± 63.92; p <0.05).