Thus, a 12-ounce (oz) glass of beer contains between about 5 to 20 g of alcohol, and a 5-oz glass of wine contains between about 12 to 18 g, and a 1 ½-oz shot of hard liquor contains about 14 g. Risk of liver disease increases markedly for men who drink > 40 g, particularly > 80 g, of alcohol / day (eg, about 2 to 8 cans of beer, 3 to 6 shots of hard liquor, or 3 to 6 glasses of wine) for > 10 years.