We studied the correlation between the pathologic kidney injury and the clinical and biochemistry manifestations in patients with lupus nephritis (LN) in the hope of helping physicians to choose the appropriate treatment in the case that the renal biopsy is not available. Patients and method: This was a descriptive cross-sectional study of patients with lupus nephritis treated in the Department of Nephrology and Urology, 115 Hospital, between Feb/2004 and Feb/2007.