Results: In the carrageenan-induced paw edema model: After 5 hours of inflammation, DHLD at the dose of 450 mg / kg mouse reduced the paw volume without statistical significance compared to the control group; DHLD at the dose of 560 mg / kg mouse reduced the paw volume 44.25% compared to the control group (P<0.01); DHLD at the dose of 750 mg / kg reduced the paw volume 54.08% compared to the control group (P < 0.001).