The average time to open eyes is 7.30 ± 0.65 minutes, time to withdraw the endotracheal tube, an average of 8.79 ± 0.63 minutes, time that the patient was transferred to the covery room, an average 10.57 ± 0.80minutes, the patients stays at recovery room is 17.93 ± 1.1 minutes Conclusions: General anesthesia with desflurane in laparoscopic surgery for acute appendicitis have good results, anesthesia smoothly, quickly revived, the airway reflexes early recovery, less hemodynamic changes, the indexes of heart rate, arterial blood pressure is always in the normal limits.