Treatment of Unstable Angina Prehospital care: Oxygen, aspirin, nitrates, and triage to an appropriate medical center Drug treatment: Antiplatelet drugs, antianginal drugs, anticoagulants, and in some cases other drugs Angiography to assess coronary artery anatomy Reperfusion therapy: Percutaneous coronary intervention or coronary artery bypass surgery Post-discharge rehabilitation and chronic medical management of coronary artery disease Prehospital care Oxygen Aspirin Nitrates Triage to appropriate medical center A reliable IV route must be established, oxygen given (typically 2 L by nasal cannula), and continuous single-lead ECG monitoring started.