Cat-Scratch Disease (Cat-Scratch Fever) By Larry M Bush, MD, FACP, Charles E Schmidt College of Medicine, Florida Atlantic University; Maria T Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center Reviewed / Revised Apr 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Topic Resources Cat-Scratch Disease Cat-scratch disease is infection caused by the gram-negative bacterium Bartonella henselae.