J Allergy Clin Immunol 130 (3 Suppl): S1-S24, 2012. doi: 10.1016 / j. jaci.2012.07.002 Treatment of SADNI Pneumococcal conjugate vaccine Sometimes prophylactic antibiotics and sometimes immune globulin replacement therapy Patients should be vaccinated with the pneumococcal conjugate (eg, 13-valent) vaccine.