Background: The aims of this study were to review the applicability, morbidity, complication and short term results of local resection of ampullary adenocarcinoma Methods: From July 2004, those patients with advanced age, who were seriously sick with many concomitant illnesses or those denying Whipple procedure, however having no evidence of local invasion or distant metastasis were indicated local resection of ampullary adenocarcinoma instead of temporary bypass procedures (biliary - intestinal anastomosis or gastro-jejunostomy).