Table 3.8 Efficacy of reducing HBV DNA load before and after treatment in LAM and TDF groups (log10 copies / ml) Reduction in HBV DNA (log10 copies / ml) Treatment group p LAM n (%) TDF n (%) ≤ 2.4 log10 25 (64.1) 9 (22.0) 0.006 2.5 - 3.4 log10 8 (20.5) 3 (7.3) 0.132 3.5 - 4.4 log10 3 (7.7) 14 (34.1) 0.008 ≥ 4.5 log10 3 (7.7) 15 (36.6) 0.005 Total 39 (100) 41 (100) In TDF-treated pregnant women, the HBV DNA load after treatment was reduced by ≥ 3.5 log10 copies/ml.