This was a cross-sectional descriptive study conducted among mothers and their children under 6 years of age at Muongla, Sonla province in 2014. Results showed that: The rate of skin diseases in the river basin: dermatitis (46.9%), rash (25.6%), scabies (6.8%); in the highland group: rash (21.4%), scabies (13.7%), eczema (9.1%).