Results: There are 163 patients in ouz study include 127 (80%) patients who have at least one complication: constipation rate 47.2%, hyperglycemie rate 21.5%, intracranial hypertention rate 22.1%, cardiovascular complication rate 30.1%, complication rate 30.1%, pneumonia complication rate 35%, seizure rate 6.7%, gastrointestinal bleeding rate 7.4%, urinary retention rate 23.9%, urinary tract infection rate 9.2%, skin ulcer rate 15.3% and hyponatremia rate 9.8%.