The potential extract was performed the in vivo acute toxicity and evaluated the criteria for quality control following Vietnamese Pharmacopoeia guideline Results: The result of SRB assay showed that ethanol extract had a cytotoxicity on Hep G2 and MCF-7 cell line higher aqueous extract with IC50 0.61 ± 0.01 (Hep G2) and 0.38 ± 0.01 (MCF-7) mg / mL.