Methods: A cross-sectional and descriptive study was carried out from 2017 to 2018, a total of 199 ESBL-producing E coliisolates from healthy individuals and clinical specimens were tested for ESBL genes including: blaTEM, blaSHV, blaCTX-M1, blaCTX-M2, blaCTX-M8/25, blaCTX-M9 by multiplex-PCR using specific primer pairs.