Treatment of NASH aims to Reduce weight Control risk factors and comorbidities It may involve Recommending weight loss of 7 to 10% of body weight via dietary changes and exercise Treating concomitant metabolic risk factors such as hyperlipidemias and insulin resistance Stopping drugs associated with NASH (eg, amiodarone, tamoxifen, methotrexate, corticosteroids such as prednisone or hydrocortisone, synthetic estrogens) Avoiding exposure to toxins (eg, pesticides) No pharmacotherapy is currently recommended specifically for the treatment of NASH Autoimmune hepatitis (See also the American Association for the Study of Liver Disease's practice guideline Diagnosis and Management of Autoimmune Hepatitis.)