Treatment For Bartter syndrome, nonsteroidal anti-inflammatory drugs (NSAIDs) Sodium, potassium, and magnesium supplements Because renal prostaglandin E2 secretion contributes to the pathogenesis in Bartter syndrome, NSAIDs (eg, oral indomethacin 0.33 to 1.33 mg / kg 3 times a day or 0.25 to 1 mg / kg 4 times a day, ibuprofen 5 to 10 mg / kg 3 times a day) (1, 2).