Pregnancy-related criteria include the following: ≥ 1 unexplained deaths of a morphologically normal (via ultrasonography or direct examination) fetus at ≥ 10 weeks gestation ≥ 1 premature births of a morphologically normal neonate at ≤ 34 weeks gestation because of eclampsia or severe preeclampsia or with features of placental insufficiency ≥ 3 unexplained consecutive spontaneous pregnancy losses at ≤ 10 weeks gestation, with maternal anatomic and hormonal abnormalities and paternal and maternal chromosomal causes excluded Treatment Prophylaxis with anticoagulants and low-dose aspirin Women with antiphospholipid syndrome are usually treated prophylactically with anticoagulants and with low-dose aspirin during pregnancy and for 6 weeks postpartum.