Fasciotomy (ie, for compartment syndrome) is rarely indicated and should be considered only when compartment pressure is ≥ 30 mm Hg for > 1 hour or < 30 mm Hg below the diastolic pressure, causes severe vascular compromise, is unresponsive to limb elevation and mannitol 1 to 2 g / kg IV, and appropriate doses of antivenom have failed.