The most common cancers associated with paraneoplastic syndromes include Lung carcinoma (most common), especially small cell lung cancer Renal cell carcinoma Hepatocellular carcinoma Leukemias Lymphomas Breast cancer Ovarian cancer Neuroendocrine cancers Stomach cancer Pancreatic cancer Successful treatment is best achieved by controlling the underlying cancer, but some symptoms can be controlled with specific drugs (eg, cyproheptadine or somatostatin analogs for carcinoid syndrome, bisphosphonates and corticosteroids for hypercalcemia).