Urine culture: 91% were positive for Gram - negative bacteria, of which E coli accounted for 61%, P aeruginosa was 8%; E coli is highly sensitive to fosfomycin (93.8%), meropenem (93.2%), piperacillin + tazobactam (84.9%) and amikacin (71.2%); resistant to >50% of fluoroquinolone antibiotics and cephalosporin generations, >80% of betalactams and folic acid inhibitors.