However, taking high methadone dosage would also reduce the risk of non-adherence if patients took 60 - 119mg methadone per day (aOR=0, 40; 95% CI: 0, 17 - 0, 94, p = 0, 036) and above 120mg / day (aOR=0, 28; 95% CI: 0, 09 - 0, 86, p = 0, 026), comparing to group of taking under 60mg.