J Allergy Clin Immunol Pract 9 (1): 132 - 150.e3, 2021. doi: 10.1016 / j. jaip.2020.08.046 Prevention Long-term prophylaxis Drugs used for long-term prophylaxis of hereditary angioedema episodes include Plasma-derived C1 inhibitor (human) Lanadelumab Berotralstat Attenuated androgens Antifibrinolytics (eg, tranexamic acid) Plasma-derived C1 inhibitor may be given in regular IV infusions or subcutaneous injections as long-term prophylaxis.