Enterococci typically cause Urinary tract infections Bacteremia Endocarditis Intra-abdominal and pelvic infections Skin, soft tissue, and wound infections Treatment of Enterococcal Infections Varies by site of infection and susceptibility testing (See also the American Heart Association's 2015 Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications.)