Etiology of Hypoparathyroidism Hypoparathyroidism results from a parathyroid hormone (PTH) deficiency, which can occur in Removal of or damage to several parathyroid glands during thyroidectomy or parathyroidectomy Inherited or autoimmune disorders Postoperative hypoparathyroidism Transient hypoparathyroidism is common after thyroidectomy, but permanent hypoparathyroidism occurs after < 3% of such thyroidectomies done by experienced surgeons.