To increase the efficacy of METHOTREXATE, the association of MIFEPRISTONE has been proposed Objectives: this study was carried out in order to determine the effectiveness of MTX and Mifepristone for treatment of tubal ectopic pregnancy. Study design: A non controlled clinical trial was conducted from jul 2008 to may 2009 at Hùng Vương hospital to assess MTX plus Mifepristone efficcacy in medical treatment of un ruptured ectopic pregnancies.