Selecting all the patients who were teachers came to be examined and treated asthma according to GINA's guideline, had the 2nd examination after the 1st one 2 - 10 weeks and the 3rd examination after the 1st one 10 - 12 weeks from June 1st 2008 to December 31th 2009.Results: 64 patients has been recruited female / male ratio 3/1, median time to have asthma: 13.5 years, allergic history: 65.6% (included allergic rhinitis: 57.5%), new-onset asthma: 84.4%.