In present, Intravenous Immunoglobulin (IVIg) and Prednisone are two widely used drugs in the treatment of immune thrombocytopenic purpura (ITP), but their long-term effectiveness is still being debated issue. Objectives: To determine the effectiveness of IVIg and Prednisone in the treatment of childhood immune thrombocytopenic purpura (ITP) at HCMC Blood transfusion - Hematology Hospital.