Diagnosis of Hemolytic Disease of the Fetus and Neonate Maternal blood and Rh typing and reflex antibody screening Serial antibody level measurements and middle cerebral artery blood flow measurements for pregnancies considered at risk Cell-free fetal DNA screening At the first prenatal visit, all women are screened for blood type, Rh type, and anti-Rho (D) and other antibodies that are formed in response to antigens and that can cause erythroblastosis fetalis (reflex antibody screening).