Background: To determine the molecular subtypes and correlation between molecular subtypes and histopathological features in breast cancer in Vietnam and Italy. Material and method: 88 patients with invasive breast carcinoma (BC) in both Hue Central Hospital and Hue University Hospital in Vietnam during 1 year from April 2016 to April 2017 as well as 235 patients from the same category of women in Sassari University Hospital, Italy during the year 2016 were collected.