Combination of daily interventions for schools, families and pupils, especially the physical activity with specific quantitative assessments, pre - and post-intervention comparisons, post-intervention results revealed improvement in the situation of dyslipidemia, hyperglycemia, BMI decreased, the effectiveness of interventions for the children with overweight and obesity was 7.3% (for obese group only was 19.2%), the research results of the thesis are very valuable for community interventions and treatment of pediatric patients with severe overweight and obesity thereafter.