Objectives: (1) To investigate the prevalence of ESBL-producing bacille detected from cases of nosocomial and community infections; (2) To study the antibiotic resistance of detected species. Method: FROM 10/2006 to 12/2006, we carried out a survey of the prevalence of Extended-Spectrum Beta-Lactamse producing bacteria among 214 Gram-Negative Bacilli isolated at Hue central hospital.