Corticosteroids (eg, prednisone 60 to 80 mg orally once a day for 1 week, followed by rapid tapering of the dose) may be used in patients with speciﬁc indications (eg, connective tissue disorder, autoimmune or uremic pericarditis, failure to respond to colchicine or NSAIDs) but are not given routinely because they enhance viral multiplication and recurrence is common when the dosage is tapered; colchicine may be particularly useful during the taper.