Treatment of Uveitis Corticosteroids (usually topical) and sometimes other immunosuppressive drugs Cycloplegic-mydriatic drugs Sometimes antimicrobial drugs Sometimes surgical therapy Treatment of active inflammation usually involves corticosteroids given topically (eg, prednisolone acetate 1% one drop as frequently as every hour while awake for severe inflammation) or by periocular or intraocular injection along with a cycloplegic-mydriatic drug (eg, homatropine 2% or 5% drops or cyclopentolate 0.5% or 1.0% drops, either drug given 2 to 4 times / day depending on severity).