Brain herniation due to tumors is treated with mannitol (recommended dosage is 0.5 to 1.5 g / kg / dose IV with mannitol 20 to 25% concentration every 4 to 6 hours as required,) a corticosteroid (eg, dexamethasone 16 mg IV, followed by 4 mg orally or IV every 6 hours), and endotracheal intubation.