The average FMD value in healthy people ranges from 9% - 21%, it is still within the allowed range according to the guidelines of the European Heart Association. Decreased FMD follow by age group, menopause time Menopausal women aged 40 - <50 reduce the rate of FMD (17.6%), and age 50 - 60 years reduce FMD (33.5%), (p <0.001).