Results: HBcrAg levels in the groups of Hepatitis B e antigen (HBeAg) - positive chronic infection (EPCI), HBeAg-positive chronic hepatitis (EPCH), HBeAg-negative chronic infection (ENCI), HBeAg-negative chronic hepatitis (ENCH), Hepatitis B s antigen (HBsAg) clearance (SC) were 6.84±0.45 logU / ml; 6.7±0.59 logU / ml; 3.15±0.86 logU / ml; 4.75±1.57 logU / ml; 2.43±0.44 logU / ml, respectively.