Causes of parkinsonism can be identified by the following: A thorough history, including occupational, drug, and family history Evaluation for neurologic deficits characteristic of neurodegenerative disorders other than Parkinson disease Neuroimaging when indicated Deficits that suggest neurodegenerative disorders other than Parkinson disease include gaze palsies, signs of corticospinal tract dysfunction (eg, hyperreflexia), myoclonus, autonomic dysfunction (if early or severe), cerebellar ataxia, prominent dystonia, ideomotor apraxia (inability to mimic hand motions), early dementia, early falls, and confinement to a wheelchair.