Drugs that can be effective are Methylphenidate (5 to 10 mg orally once or twice a day, titrated by 5 mg every 3 days to a maximum dose of 40 mg a day) Dextroamphetamine (initially, 2.5 mg orally once or twice a day) Modafinil (initially, 100 mg orally for 3 to 7 days, then 200 mg orally once a day) These drugs are typically given in the morning and as needed later.