Herpes Zoster Ophthalmicus (Herpes Zoster Virus Ophthalmicus; Ophthalmic Herpes Zoster; Varicella-Zoster Virus Ophthalmicus) By Melvin I Roat, MD, FACS, Sidney Kimmel Medical College at Thomas Jefferson University Reviewed / Revised Aug 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Prevention Key Points Topic Resources Herpes Zoster (V1 Distribution... Herpes zoster ophthalmicus is a reactivated latent varicella-zoster virus (VZV) infection (shingles) involving the eye.