The factors related to Group B streptococci vagina and rectum infection in pregnancies at 24 - 37 week's gestation: use of domestic well water increases the risk of GBS infection (OR) = 2.56, 95% CI 1.08 - 6.25, intercourse during pregnancy increases the risk of GBS infection (OR= 2.38, 95% CI 1.14 - 5), douching habits increased risk of GBS infection (OR=2.43, 95% CI 1.13 - 5) Conclusion: Universal screening at 24 - 37 weeks' gestation gestation diabetes mellitus for maternal GBS colonization and use of intrapartum antibiotic prophylaxis has resulted in substantial reductions in the burden of earlyonset GBS disease among newborns.