Also, COVID-19 pneumonia may resemble the ischemia-related lung changes of PE on chest CT (Figure 2C) .17, 18, 20, 21 Indications for computed tomography pulmonary angiogram (CTPA) in COVID-19 patients include high demand for supplementary oxygen despite limited lung disease, unexplained severe respiratory failure, abnormal coagulation parameters, hemodynamic compromise, and right heart chamber dilation.11, 58, 63, 64 Care providers should always consider the risks of spreading infection by transporting severely ill patients to the CT scanner suite and the renal impairment risks by administering potentially nephrotoxic intravenous contrast material prior to any CTPA. 65 There are also special considerations for CTPA in evaluating for PE in COVID-19 patients.