When the Child-Pugh score increased, the odd of depression also increased with OR = 1.35; 95% CI (1.15 - 1.59), the more severe cirrhosis, the higher the odd of depression with OR = 2.39; 95% CI (1.4 - 4.08), and the higher the Child-Pugh score, the more severe depression level is with OR = 1.22; 95% CI (1.01 - 1.46), patients with depression increased the odd of mortality with OR = 2.35; 95% CI (1.16 - 4.76).