The following are examples: Almost universal sympathetic denervation of the heart, contributing to orthostatic hypotension Esophageal dysmotility, contributing to dysphagia and increased risk of aspiration Lower bowel dysmotility, contributing to constipation Urinary hesitancy and / or urgency, potentially leading to incontinence (common) Anosmia (common) In some patients, some of these symptoms occur before the motor symptoms of Parkinson disease and frequently worsen over time.