For a continuous drip, 1 mg epinephrine is mixed in 250 mL 5% D / W or 0.9% normal saline for a concentration of 4 mcg / mL and is started at 0.1 mcg / kg / minute and titrate up by 0.05 mcg / kg / min every 2 to 3 minutes as needed based on blood pressure, heart rate, and oxygenation.