Results: Alcohol poisoning: the lactate levels of methanol poisonings on admission were higher than those of ethanol poisonings (9.4 vs 4.7 mmol / l; p<0.01); lactate returned to normal more slowly (27.8 vs 8.2 hours; p<0.01); Patients with methanol intoxication were admitted to hospital later, had higher rates of severe complications and multi-organ failure than ethanol poisoned patients (p<0.01); the patients were only died from methanol poisoning (40%), lactate on admission ≥10 mmol / L had mortality rate of 66.7%.