For patients who are eligible for acute reperfusion therapy except that BP is > 185/110 mm Hg, BP can be treated to decrease BP to below > 185/110 mm Hg0 t with one of the following: Labetalol 10 to 20 mg IV bolus over 1 to 2 minutes (may repeat 1 time) Nicardipine 5 mg / hour IV infusion initially (dose is increased by 2.5 mg / hour every 5 to 15 minutes to a maximum of 15 mg / hour) Clevidipine 1 to 2 mg / hour IV infusion (titrate by doubling the dose every 2 to 5 minutes until desired BP is reached to a maximum of 21 mg / hour) Patients with presumed thrombi or emboli may be treated with one or a combination of the following: tPA, thrombolysis-in-situ, and / or mechanical thrombectomy Antiplatelet drugs Anticoagulants Most patients are not candidates for thrombolytic therapy; they should be given an antiplatelet drug (usually aspirin 325 mg orally) when they are admitted to the hospital.