Glomerular disorders are classified based on urine changes as those that manifest predominantly with Nephrotic-range proteinuria and nephrotic urine sediment (fatty casts, oval fat bodies, but few cells or cellular casts) Hematuria, usually in combination with proteinuria (which may be in the nephrotic range); the red blood cells (RBCs) are usually dysmorphic and often there are RBC or mixed cellular casts (nephritic urine sediment) Nephrotic syndrome is nephrotic urine sediment plus edema and hypoalbuminemia (typically with hypercholesterolemia and hypertriglyceridemia).