Results: (1) Platelet count and bleeding symptom are related, with average platelet count in bleeding group is significant lower than in non-bleeding group (32, 7 G / l and 59, 2 G / l; respectively with p< 0, 001); lower platelet count leads to more severe bleeding, especially when platelet count is less than 50 G / l; (2) DIC leads to more severe bleeding symptom in acute leukemia; DIC is observed mostly in APL (AML M3) but sometimes can be seen in other subtypes such as AML M4 or L2 in this study.