Symptoms, when they occur, vary by location: Carotid arteries: Transient ischemic attack or stroke symptoms Intra-abdominal arteries: Mesenteric ischemic symptoms (rare) Intracranial arteries: Symptoms of brain aneurysm Leg arteries: Claudication in the thighs and calves, femoral bruits, and decreased femoral pulses Renal arteries: Secondary hypertension Ultrasonography may suggest the diagnosis, but definitive diagnosis of fibromuscular dysplasia is made by angiography showing a beaded appearance (in medial or perimedial dysplasia) or a concentric band or long, smooth narrowing (in other forms).