J Am Coll Cardiol 79 (2): e21-e129, 2022. doi: 10.1016 / j. jacc.2021.09.006 Anticoagulant Drugs Either a low molecular weight heparin (LMWH), unfractionated heparin, or bivalirudin is given routinely to patients with acute coronary syndrome unless contraindicated (eg, by active bleeding or planned use of streptokinase or anistreplase).