The morphology and size of Y-90 microspheres were checked by field emission scanning electron microscopy (FE-SEM), chemical purity was checked by energy-dispersive X-ray spectroscopy (EDX), radionuclide purity was analysed by gamma ray spectrometer Canberra-GC-3019 - 7500SL, radiochemical purity was checked by the instant thin layer chromatography, toxic heavy metals (ICP-MS), and sterility, bacterial endotoxins, and product stability over time were analysed by British Pharmacopoeia 2016.