Age-Related Macular Degeneration (AMD or ARMD) (Senile Macular Degeneration) By Sonia Mehta, MD, Vitreoretinal Diseases and Surgery Service, Wills Eye Hospital, Sidney Kimmel Medical College at Thomas Jefferson University Reviewed / Revised Apr 2022 | Modified Sep 2022 View Patient Education Etiology Pathophysiology Symptoms and Signs Diagnosis Treatment Key Points Topic Resources Normal Retina Age-Related Macular Degeneration... Age-Related Macular Degeneration... Age-Related Macular Degeneration... Age-Related Macular Degeneration... Age-related macular degeneration (AMD) is the most common cause of irreversible central vision loss in older patients.