About the changes of serum ferritin: before treatment, the rate of ferritin > 10000ug / l was 73.7% in the dead patients group, median serum ferritin in this one was 11325 ug / l (282 - 25720 ug / l; in the incompletlely responsive patients group was 4688 ug / l (406 - 13896 ug / l), and was 787 ug / l (59 - 13346 ug / l) after 8 weeks; in the completlely responsive patients group was 3337ug / l (258 - 55120 ug / l), and was 104ug / l (22.5 - 10914 ug/l) after 8 weeks.