Botulism By Larry M Bush, MD, FACP, Charles E Schmidt College of Medicine, Florida Atlantic University; Maria T Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center Reviewed / Revised Jun 2023 View Patient Education Symptoms and Signs Diagnosis Treatment Prevention Key Points More Information Botulism is poisoning that is due to Clostridium botulinum toxin and that affects the peripheral nerves.