Clostridial Intra-Abdominal and Pelvic Infections By Larry M Bush, MD, FACP, Charles E Schmidt College of Medicine, Florida Atlantic University; Maria T Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center Reviewed / Revised Jun 2023 View Patient Education Symptoms and Signs Diagnosis Treatment Key Points Clostridia, primarily Clostridium perfringens, are common in mixed intra-abdominal infections resulting from a ruptured viscus or pelvic inflammatory disease.