Transitional medications include NSAIDs Corticosteroids Dihydroergotamine Prochlorperazine Clonidine (preferred if the overused medication was an opioid) Phenobarbital (used to prevent withdrawal seizures if the overused medication was a barbiturate) After medication overuse headache has been treated, patients should be instructed to limit acute use of all headache medications as follows: For NSAIDs: < 6 days / month For triptans, ergotamine, or combination analgesics: < 4 days / month Use of previously overused medications is discouraged.