It can develop in healthy people, but patients at increased risk include those with Rheumatoid arthritis HIV infection Immunosuppression (eg, hematologic or other cancers, immunosuppressive drug use) Prosthetic joints Examples of possible causes are Mycobacterium tuberculosis, M marinum, M kansasii, Candida species, Coccidioides immitis, Histoplasma capsulatum, Cryptococcus neoformans, Blastomyces dermatitidis, Sporothrix schenckii, Aspergillus fumigatus, Actinomyces israelii, and Brucella species.