Relationship between hyponatremia and location of the injury Location of injury Hyponatremia (n=180) Normal (n=208) OR (95% CI) p Frontal lobe (12) Yes 22 (66.7%) 11 (33.3%) 2, 5 (1, 2 - 5, 3) < 0, 01 No 158 (44.5%) 197 (55.5%) 1 Central gray (94) Yes 30 (31, 9%) 64 (68, 1%) 1 < 0, 01 No 150 (51%) 144 (49%) 2, 2 (1, 4 - 3, 6) Ventricle (81) Yes 52 (64, 2%) 29 (35, 8%) 2, 5 (1, 5 - 4, 2) < 0, 001 No 128 (41, 7%) 179 (58, 3%) 1 Comment: Patients with frontal lobe lesions had 2.5 times higher risk of hyponatremia than patients without frontal lobe lesions (p <0.01).