Table 3.10: Distribution of methadone doses of the study subjects Methadol doses are being used (mg) Cases n (%) Controls n = 161; n (%) (2) p1, 2 Dropped out n = 28 Missed > 5 consecutive days n = 53 All n = 81 (1) 5 - 59 mg 10 (35, 7) 34 (64, 2) 44 (54, 3) 43 (26, 7) 0, 000 60 - 119 mg 11 (39, 3) 14 (26, 4) 25 (30, 9) 62 (38, 5) 120 - 380 mg 7 (25, 0) 5 (9, 4) 12 (14, 8) 56 (34, 8) ± SD (mg) 78, 0 ± 43, 8 57, 1 ± 43, 6 64, 3 ± 44, 5 111, 7 ± 78, 8 0, 000 Comments: The proportion of patients was treated with methadone doses less than 120 mg / day and the mean of methadone dose in both groups was statistically significant (p <0.01).