Aims: To determine the prevalence, spectrum and clinical characteristics of erosive esophagitis and the complications of gastro-esophageal reflux disease (CERD) in Vietnamese patients with dyspepsia symptoms undergoing upper gastrointestinal endoscopy. Methods: This is a cross-sectional study conducted between October 2003 and April 2004 at the UniversityMedical Center in Hochiminh City, Vietnam.