Telavancin dosing is based on creatinine clearance: Creatinine clearance > 50 mL / minute: 10 mg / kg IV every 24 hours Creatinine clearance 30 to 50 mL / minute: 7.5 mg / kg every 24 hours Creatinine clearance 10 to < 30 mL / minute: 10 mg / kg every 48 hours Creatinine clearance < 10 mL / minute: Data limited, no recommendations available