The multivariable logistic regression analysis showed that moderate anxiety disorder (OR = 2.19, 95% CI = 1.35 - 3.56, p=0.001), severe / very severe anxiety disorder (OR = 2.69, 95% CI = 1.47 - 4.94, p=0.001) and family history of GERD (OR = 2.10, 95% CI = 1.28 - 3.42, p=0.003) were independent risk factors of GERD in medical students.