Materials and methods: Marketing activities of Astrazeneca for Nexium® are studied by using crosssectional descriptive study methods. Results: Although the macro, micro and internal elements created the strengths, weaknesses, opportunities and also challenges for businesses of AstraZeneca's Nexium® products, the company has a effective combination of the product policy (the strategy of new drug development and broadening product list), price policy (skimming price and constant price), monopoly distribution policy and promotion policy (pull and push strategy) for Nexium®marketing activities. Conclusions: The research has analyzed the impacts ofenvironmental factors as well as the marketing-mix policy which has been applied for Nexium® products of AstraZeneca pharmaceutical company.