For pregnancies of < 10 weeks, regimens include the progesterone - receptor blocker mifepristone (RU 486) and the prostaglandin E1 analog misoprostol, as follows: Mifepristone 200 mg orally, followed by misoprostol 800 mcg buccally at 24 to 48 hours (for pregnancies of 9 to 11 weeks, an additional dose of misoprostol 800 mcg buccally is taken 4 hours after the initial misoprostol dose) Both mifepristone and misoprostol may be self-administered by the patient and do not need to be given at a clinic or hospital.