Background: Phosphore-calci and PTH disorders secondary to chronic kidney disease such as hyperphosphatemia, hypocalcinemia, and secondary hyperparathyroidism can cause many clinical signs and symptoms such as arthritis, pruritus, paresthesia, muscle weakness, muscle clonus, squeletal pain, cramps, and other lethal complications such as systemic calcification, especially coronary calcification, and renal osteodystrophy with pathological bone fracture.