Renal Tubular Acidosis By L Aimee Hechanova, MD, Texas Tech University Health Sciences Center, El Paso Reviewed / Revised May 2022 | Modified Sep 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Key Points Topic Resources Some Features of Different... Renal tubular acidosis (RTA) is acidosis and electrolyte disturbances due to impaired renal hydrogen ion excretion (type 1), impaired bicarbonate resorption (type 2), or abnormal aldosterone production or response (type 4).