The risk factors of nosocomial infection were: age < 1 year (RR = 1, 9 (1, 1 - 3, 4)); malnutrition II, III (RR = 2, 0 (1, 1 - 4, 2)); PRISM > 10 (RR = 5, 4 (2, 4 - 11, 9)); intubation (RR = 2, 3 (1, 3 - 4, 0); parenteral nutrition (RR = 2, 8 (1, 3 - 5, 9); central venous catheter (RR = 2, 8 (1, 3 - 5, 9); bladder catheter (RR = 5, 7 (3, 0 - 10, 7)).