To evaluate the efficacy of treatment by Cyclosporin A for severe psoriasis vulgaris. 2 New contributions of the thesis - Quantification of serum levels of IL-2, IL-6, IL-8, IL-10, IL - 12, IL-17, TNF-α, IFN - before and after treatment with Cyclosporine A: + Before treatment: serum levels of IL-6, IL-8, IL-10, IL-12, IL-17, TNF-α, IFN - were higher than the control group.