The proportion of patients with reported significant deterioration of quality of life, GERD-induced disturbed sleep and reduced productivity before and after treatment were (69.7% vs 56.2%, p <0.001), (34.8% vs 18.8%, p <0.001), and (53.1% vs 13.9%, p <0.001) Conclusions: Symptom control and patient satisfaction are still not meet treatment needs for a significant proportion of GERD patients even with an excellent adherence.