To evaluate the results of treatment of subacromial impingement syndrome with corticosteroid injection under ultrasound guidance and to comment on some undesirable effects of the therapy. Methods: Interventional study longitudinal follow-up 29 patients with 34 injured shoulder joints, diagnosed with subacromial impingement syndrome and received 1 injection of Methylprednisolone acetate 40mg (Depomedrol 40mg) into the subacromial bursa under ultrasound guidance.