Subject and method: A cross-sectional study with convenient sampling, 208 atopic dermatitis patients at the Ho Chi Minh City Hospital of Dermatology and Venereology during the period September 2019 to September 2020 were enrolled in this study, diagnostic criteria for atopic dermatitis was based on modified Hanifin and Raijka criteria and the severity of anxiety - depression disorder was evaluated by using HADS score.