Relationship between hyponatremia and lesion size 13 Table 3.24.Relationship between hyponatremia and lesion size Volume of injury (cm3) Hyponatremia (91) Normal (122) p <30 52 (35, 9%) 93 (64, 1%) <0, 05 30 - 60 24 (54, 5%) 20 (45, 5%) >60 15 (57, 7%) 11 (42, 3%) Comment: There was a statistically significant relationship (p <0.05) between hyponatremia and brain lesion size, the greater the volume of lesions, the higher the rate of hyponatremia.