There were statistically significant correlations between patients' discharge status, physician's adherence to treatment guidelines, adherence to professional regulations and readmission rate within 48 hours (p< 0.001, chi-square). Conclusion: This study indicated that the physicians'adhererance to treatment guidelines professional regulations, as well as patient's adherence to physicians'advice and treatment regimens play pivotal roles in reducing hospital readmissions, and need to be improved.