Risk factors Risk factors for intraamniotic infection include the following: Prolonged rupture of membranes (a delay of ≥ 18 to 24 hours between rupture and delivery) Premature rupture of membranes (PROM) Preterm labor Meconium-stained amniotic fluid Presence of genital tract pathogens (eg, group B streptococci) Multiple digital examinations during labor in women with ruptured membranes Long labor Internal fetal or uterine monitoring Complications Intraamniotic infection can cause as well as result from preterm PROM or preterm delivery.