Fexinidazole is taken orally once a day for 10 days at the following doses: For patients ≥ 35 kg: 1800 mg / day in the loading phase (4 days), followed by 1200 mg / day in the maintenance phase (6 days) For patients 20 to 34 kg: 1200 mg / day in the loading phase (4 days), followed by 600 mg / day in the maintenance phase (6 days) Criteria for outpatient treatment with fexinidazole include reliable adherence to dosing, absence of psychiatric disorders, and body weight ≥ 35 kg.