Fracture-Dislocation of the Midfoot (Lisfranc Injury) By Danielle Campagne, MD, University of California, San Francisco Reviewed / Revised Dec 2022 View Patient Education Symptoms and Signs Diagnosis Treatment Key Points Topic Resources Fracture of the 2nd metatarsal... Lisfranc Fractures A Lisfranc injury is a fracture and / or dislocation of the midfoot that disrupts one or more tarsometatarsal joints.