show me the heart rate change in patient 4401 last measured on the current intensive care unit visit compared to the first value measured on the current intensive care unit visit?
select ( select chartevents.valuenum from chartevents where chartevents.icustay_id in ( select icustays.icustay_id from icustays where icustays.hadm_id in ( select admissions.hadm_id from admissions where admissions.subject_id = 4401 ) and icustays.outtime is null ) and chartevents.itemid in ( select d_items.itemid from d_items where d_items.label = 'heart rate' and d_items.linksto = 'chartevents' ) order by chartevents.charttime desc limit 1 ) - ( select chartevents.valuenum from chartevents where chartevents.icustay_id in ( select icustays.icustay_id from icustays where icustays.hadm_id in ( select admissions.hadm_id from admissions where admissions.subject_id = 4401 ) and icustays.outtime is null ) and chartevents.itemid in ( select d_items.itemid from d_items where d_items.label = 'heart rate' and d_items.linksto = 'chartevents' ) order by chartevents.charttime asc limit 1 )