how many patients had a microbiology fluid received in blood culture bottles test until 2101?
select count( distinct admissions.subject_id ) from admissions where admissions.hadm_id in ( select microbiologyevents.hadm_id from microbiologyevents where microbiologyevents.spec_type_desc = 'fluid received in blood culture bottles' and strftime('%y',microbiologyevents.charttime) <= '2101' )