A 57-year-old male, HIV-infected with a suppressed viral load and low CD4 count was referred to our facility from a peripheral health center for treatment of a senile cataract and right neck swelling that had been visible for 20 years. The patient had no prior history of fever or weight loss, but did report having received anti-TB treatment twice without any improvement.
On examination, he was awake, had an enlarged lymph node in his right neck that was firm and movable and had normal skin surrounding it. His physical examination was normal. Histopathology of incisional biopsy from the neck mass demonstrated a reactive lymph node highlighting prominent vascular proliferation and hyalinization of the vessel walls (Figure 3(c)), and follicle surrounded by mantle zone composed of concentric rings of small lymphocytes with onion skin like skin appearance (Figure 3(d)). Test for HHV-8 was positive; the findings were in favor of CD. He was scheduled for surgical resection whose histopathology confirmed the diagnosis of CD. The patient was advised to maintain follow-up as outpatient after surgical resection and has been well for almost 1 year after the surgery.