A 10-week-old baby boy presented to Chawama First Level Hospital in Lusaka, with a history of i) coughing for 2 weeks prior to the visit, ii) sneezing, iii) refusing to breastfeed, iv) intermittent fevers, and v) general irritability and being difficult to console. His medical history revealed that he was HIV exposed (HEI) and had been on neonatal prophylaxis (Nevirapine 1.5 mL OD, Zidovudine/lamivudine 1.5 mL BD, Cotrimoxazole 2.5 mL OD) from birth and HIV DNA PCR testing done at 6 weeks was negative. The child was born at term via spontaneous vaginal delivery, had a birth weight of 3.8 kg, was exclusively breastfed, and received all age-appropriate vaccinations (BCG and OPV at births; OPV, PCV, Rota, and HepB, HiB, DPT at 6 weeks). There was no family history of sickle cell disease or positive tuberculosis contact.