A 13-year-old boy presented to Department of Orthopedics with pain and swelling in the right ankle. Swelling had appeared about 1 year back and was gradually increasing in size. Examination revealed bony thickening over the lateral malleolus. Ankle and subtalar joints had full range of mobility. Parameters of complete blood count were within normal range. ESR was 68 mm at 1st hour. Plain radiography revealed a submetaphyseal lytic lesion in the distal tibia with a sclerotic margin around it (Figure 1). With these findings, a diagnosis of Brodie's abscess was made. Curettage was done under spinal anesthesia through the anterior approach. Curetted material was sent for histopathological and microbiological assessment. 
 On gross examination, specimen consisted of multiple, soft, gray brown to gray white tissue bits, with largest measuring 0.5 x 0.5 x 0.3 cm. Histopathology showed small irregular necrotic bony fragments and degenerated cartilage, surrounded by mixed inflammatory cell infiltration consisting of plenty of foamy histiocytes along with lymphocytes and plasma cells (Figure 2). Few neutrophils and occasional histiocytic giant cells were also seen. Fibrosis was present. All these features were consistent with xanthogranulomatous osteomyelitis. From the tissue sent for culture, staphylococcus aureus was isolated. PCR study for Mycobacterium tuberculosis was negative. Patient recovered completely after the surgery.