A 25-year-old Caucasian male contact lens wearer, with a CFTR-RD diagnosis per patient since childhood, presented seeking refractive surgery. He did not complain of any ocular or systemic issues of CFTR-RD. The patient stated he was not taking CF medications and had no family history of CF. Preoperatively, his manifest refraction was -2.75 D OU and his corneal thickness was approximately 585 mum OU. Corneal and conjunctival staining revealed no remarkable findings. His Schirmer's test was above 10 mm in 5 minutes and his TBUT was greater than 7 seconds. LASIK was performed using an iFS  Advanced Femtosecond IntraLase  Laser (Johnson & Johnson Surgical Vision Inc., Santa Ana, CA) to create an 8.7 mm diameter flap with a flap thickness of 110 mum. A VISX STAR S3  (Johnson & Johnson Surgical Vision Inc., Santa Ana, CA) was used to create a 6.0 mm ablation zone with a transitional zone of 8.0 mm.
Postoperatively the patient responded well but developed more dry eye symptoms relative to other LASIK patients, prompting the insertion of punctal plugs superiorly and inferiorly for approximately 6-7 months. Afterward, Refresh Plus PF Lubricant Eye Drops were prescribed for residual dryness. He had no corneal or conjunctival staining. One year postoperatively, the patient presented with 20/20 corrected vision and a refractive error of +0.5 D OD and +0.25 D OS.