Male, 54 years old, had a history of daily drinking with the amount of 100-150 g per day for 30 years, been diagnosed as "alcoholic cirrhosis" in other hospital one year ago. The patient began to feel the abdominal distension, accompanied by fatigue, yellow urine, and jaundice, one month ago. On April 11, 2012, the patient started the treatment in our hospital. After admission, the tests revealed ALT 924.6 U/L, AST 817.3 U/L, TBIL 274.2 mumol/L, and DBIL 189.4 mumol/L. With the consent of the patient, he was treated with peripheral injection of the umbilical blood stem cells (UC-MSCs mononuclear cells 39.6 x 109/ml, flow cytometry CD34+ and CD33+ stem cells 10.1 x 106/ml with a total input volume of 40 ml). The relevant tests were performed regularly after the infusion, including ALT, ALB, TBIL, and PTA. At the same time, the patient was given supportive treatments such as stopping drinking, conventional liver protection, reducing transaminase, and eliminating jaundice as well as albumin treatment. The input of stem cells promotes the regeneration of liver cells and the recovery of various physiological functions. The changes of the patient's indicators during treatment can be seen in Table 2. The patient was discharged with a better health condition on May 21, 2012, and regular follow-up was conducted after discharge.