A 14-year-old child of an immigrant family, a native of Azerbaijan who had been living in Turkey for 10 years, presented to our clinic in September 2009 with complaints of fever, persistent headache and vomiting that lasted for 10 days. Physical examination was normal except for neck rigidity, meningeal irritation sign and mild confusion. The emergent cranial computerized tomography (CT) without contrast on admission scan showed no pathological findings. Thereby, lumbar puncture was performed to examine the cerebrospinal fluid (CSF). The findings were: CSF cell count, 57/mm3; leukocyte (60% lymphocyte), 18/ mm3; erythrocyte and glucose, 13 mg/dl (simultaneous blood glucose 109); protein, 243 mg/dl. The India ink stain was negative. Miliary pattern was suspected in the chest X-ray. Laboratory tests: WBC 12,300/mm3; hemoglobin 11.7 g/dl; CRP 12 mg/dl; anti-HIV antibody negative. On the same day, sudden loss of consciousness, bradycardia and hypotension developed and the patient was transferred to the intensive care unit (ICU). Ceftriaxone and acyclovir therapy was started due to clinical deterioration, loss of consciousness and seizure on the same day. A negative Herpes Simplex Virus (HSV) test result was obtained on the seventh day. Since the patient's mother had a pulmonary TB history and her clinical condition did not improve, antituberculous therapy with four drugs and dexamethasone was started on the second day. Then, the vital findings were found to have improved on the seventh day and she transferred to the infectious diseases ward. She was evaluated as stage III and cranial magnetic resonance imaging (MRI), which was performed on the seventh day with gadolinium, showed multiple tuberculoma in the basal ganglions, cerebral and cerebellar hemispheres, basal meningitis and minimal hydrocephalus [Figure 1]. Miliary pattern was detected in the thorax CT (HRCT) [Figure 2]. CSF polymerase chain reaction (PCR) for TB (GeneXpert MTB-RIF, Cepheid , Sunnyvale, CA, USA) and Quantiferon TB gold test (Cellestis , Australia) were positive on the third day. Mycobacterium tuberculosis was isolated from the CSF on the 21st day in Loewenstein Jensen (L-J) medium. During the hospitalization period, convulsion, hearing loss, aphasia and motor deficits developed and the patient was discharged from the hospital on the 34th day with neurological sequel (aphasia, motor deficits, mild mental defect and hearing loss). She has been followed-up in our outpatient clinic ever since.