A 40-year-old farmer, father of two kids, chronic smoker and a resident of an urban area presented to us with chief complaints of itchy oozing rash since six days following 10 days of start of antitubercular chemotherapy comprising of streptomycin (S), isoniazid (INH), rifampicin (RIF), pyrazinamide (PZA) and ethambutol (E). His other complaints where productive cough, low grade fever, exertional breathlessness and left sided chest pain since three months. As evident from a positive sputum smear for acid-fast bacilli (AFB) with radiological evidence, he was a known case of pulmonary tuberculosis. On examination, there were erythematous maculo-papular rashes with oozing serous discharge along with generalized edema, distributed characteristically over the sun exposed areas of the skin [Figure 1]. A possibility of drug-induced hypersensitivity reaction was entertained and all the ATD were discontinued and he was managed using antibiotics, anti-histaminics, steroids, hydration and avoidance of sunlight. After six days of the above intervention, the rash subsided and anti-tubercular drugs were re-introduced one by one under close observation and steroids were tapered. E was introduced first at a low dose of 200 mg. Over the next four days the dose was escalated to 800 mg with no adverse event and hence continued. Then PZA was introduced at low dose of 250 mg which was escalated to 500 mg the next day. However, by the evening, he experienced recurrence of his previous rash which became prominent, erythematous and started itching, whereupon PZA was stopped and E continued. After a few days, the rash again subsided, when RIF was introduced at a low dose of 150 mg, which was escalated to 450 mg over next 4 days without any adverse event. This was followed by addition of INH at low dose of 100 mg escalated to 300 mg over four days without any adverse event. Hence, after about three weeks, he was finally stable on RIF 450 mg, INH 300 mg and E 800 mg [Figure 2]. After another five days, introduction of PZA (250 mg) was again attempted, which resulted in recurrence of skin eruptions on the same day. Patient was labelled as having PZA-induced phototoxicity and was started on a regimen containing S, INH, RIF and E. Five months following treatment, the patient is now sputum negative for AFB.