A 32 year old Hispanic male with no significant past medical history presented to the emergency department with five days history of nausea and vomiting associated with abdominal pain. Patient stated that he has been having 8-10 episodes of non-bloody, non-projectile and non-bilious vomiting which is associated with diffuse, non-radiating, colicky abdominal pain alleviated by taking hot showers. The patient also had two days history of diarrhea which resolved on its own. The patient denied anorexia, dysphagia, heartburn, jaundice, hematemesis, excessive flatulence, bloating, constipation, tenesmus, hernia, fevers, chills, weakness, fatigue, or recent weight loss. The patient had a similar episode 2 months ago and was admitted to the hospital, for which he had a computerized tomography (CT) scan of the abdomen performed. At that time the CT showed a possible diagnosis of inflammatory bowel disease. The patient also has a 15 pack year history of smoking, along with social alcohol use, and daily marijuana use for 19 years. Physical examination upon admission revealed a well-developed, Hispanic male who was in moderate distress from pain. BP 127/70 mmHg, HR 60/min, T 97.4 F, RR 23/min, and Oxygen saturation 97% on room air. Skin was warm, dry, and without rash. Abdomen was soft with periumbilical tenderness, and without hepatosplenomegaly. The remainder of the physical exam was normal. Laboratory data showed revealed Hb 14.2, Hct 42.6, WBC 9, and Platelets 155,000. Urine toxic screen revealed positivity for THC and benzodiazepenes. The patient was admitted with possible diagnoses of cannabis induced hyperemesis and irritable bowel disease. He was started on empirical antibiotics which was discontinued after 2 days, and he was placed on Zofran and pantoprazole for relieve of nausea, however these medications failed to produce any relief. After admission, he was placed on lorazepam 1 mg IV which provided immediate improvement in his nausea. During the patient's hospital stay, he took multiple hot showers as they relieved his vomiting and abdominal pain. The total course of stay for this patient was just over 24 h and he was symptom free prior to discharge. The patient was educated on the cannabis use being the contributory factor of his sickness and he was advised to discontinue its use. He was prescribed Lorazapam 1 mg PO BID for 3 days and then was reduced to once a day for 3 days. He was followed up in outpatient clinic.