A 35-year-old male patient presented with dizziness, speech problems and cerebellar ataxia. He was HIV-positive with a CD4 count of 90 cells/microL. He was not on HAART and anti-tuberculosis treatment for pulmonary tuberculosis. On examination, he was chronically ill with nystagmus, dysarthria, dysmetria, ataxia and left-sided hemisensory loss. JC virus was found on examination of the CSF. CT scan demonstrated low density in the left cerebellar hemisphere, which did not enhance on the post contrast imaging (Figure 5). T2-weighted and FLAIR sequences on MRI demonstrated high-signal changes in the left cerebellar hemisphere, left superior cerebellar peduncle and diffusely in the pons. No enhancement or restricted diffusion was noted. The patient was discharged to the rehabilitation unit.