On DOL 17, the infant was discharged from hospital with a nasogastric tube. After symptomatic treatment, the high GGT at admission had dropped to 264 mmol/L and the PT returned to normal (16.2 s). She experienced slow weight gain and increasing TBA, which was unmanageable by drugs after discharge. When she was 3 months old, there was a continuous mild increase in methionine (Met) for 2 months. After providing Met-free formula milk, the level of Met reduced to normal, and her motor development improved. When she was 12 months old, she had a high fever of 39 C. Afterward, her gross and fine motor regressed to the level of 5 months. Now, she is 15 months old with four primary teeth and has completed a cleft palate repair surgery in order to improve her nutritional status. When she was discharged from the hospital in the first time, the GGT were maintained between 430 and 470 mmol/L, the AST were maintained between 62 and 87 U/L and albumin were maintained between 31.4 and 36.9 g/L. In addition, PT (15.1 s) and international normalized ratio (1.31) was slightly elevated at 12 months of age. Only bile acids were continuously increasing. Because she had normal stool color, normal skin color, and normal abdominal ultrasound, we excluded the extrahepatic biliary atresia and choledochal cyst and did not perform liver biopsy. She is susceptible to higher serum lactate after rehabilitation training and hypoglycemia with low ketone under starving conditions (Table 1).