A 64-year-old female patient with a history of cervical cancer was admitted in our clinic for odynophagia, anorexia and weight loss, all due to a nodular, ulcerated, infiltrating mass on the left side margin of the tongue, extending inferiorly towards the ventral surface (Figure 2). The lesion was described as a tumor, and a biopsy was taken. Chest X-ray showed bilateral diffuse micronodular and nodular opacities, and an infectious substrate was suspected. Pneumology consult raised a suspicion of secondary pulmonary tuberculosis. A surgical consult for intense abdominal pain with muscular defense established a diagnosis of acute abdomen with generalized peritonitis. An emergency segmental enterectomy of the jejune was performed. Macroscopic inspection revealed a semi-circumferential and transverse ulcer. Histopathological examination of both lingual biopsy and jejune resection specimen showed numerous caseous and non-caseous epithelioid and giant cells granulomas (Figure 3). Acid-fast bacilli were identified using Ziehl-Neelsen stain (Figure 4), and the diagnosis of lingual and jejunal tuberculosis was established. Unfortunately, the patient's postoperative evolution was severe, and she died within 10 days from being admitted in the intensive care unit, from acute circulatory and respiratory insufficiency.