A 28-year-old woman, pregnant, black, housekeeper, from Sao Francisco do Itabapoana, RJ, was admitted to the hospital on June 29th 2016, presenting weakness in the lower limbs and a consequent inability to ambulate for the previous week. The patient affirmed not having experienced similar episodes previously and claimed to be free of comorbidities. The patient reported rash on her limbs, pruritus and vomiting approximately 1 month before admission to the hospital. Initial obstetric examinations showed globular abdomen, unlimited uterus and absence of vaginal bleeding. The fetal heartbeat was not detected in the Sonar Doppler. Transvaginal ultrasonography evidenced a single fetus with longitudinal status and cephalic circumference suggesting 15 weeks of gestational age, normohydramnios, lack of heartbeat, and non-apparent active movements, which lead to the diagnosis of death and retained fetus (stillbirth). The patient was admitted to curettage and remained in hospital for 30 days. Analysis of the cerebrospinal fluid obtained by lumbar puncture and exams of the patient's peripheral blood revealed normal parameters (Table S1). The IgM serology for Dengue, Chikungunya, Zika, Epstein Barr and Cytomegalovirus were non-reactive (in further sections of this paper, diagnosis of ZIKV infection was confirmed by specific staining in placental and fetal tissues). The patient evolved to ascending and symmetrical flaccid tetraparesis, paresthesia, areflexia, presenting hands with pendular movement, dysautonomia (resting tachycardia and hypertension) and signs of respiratory insufficiency (mild dyspnea at rest which worsens upon effort), characterizing the GBS. The patient was further treated with intravenous immunoglobulin (30 g/day) for five days, atenolol 50 mg 12/12 h, amlodipine 5 mg 24 h, motor rehabilitation, respiratory physiotherapy and psychological intervention. In the second week of disease evolution, the neurological examination showed symmetric flaccid tetraparesis, motor incoordination, global areflexia and sensitive disorders (tactile and thermal distal hypoesthesia). Neurological follow up during and after the hospitalization period are described in Table S2. During the fourth week of disease progress, the patient was admitted to electroneuromyography, which revealed peripheral, acquired, chronic, symmetrical, diffuse, myelin and axonal (predominantly myelin), sensory and motor polyneuropathy: a condition that affected the peripheral nerves of the upper and lower limbs. In addition to that, the patient showed signs of neurogenic myopathy and muscular denervation. Together, these findings were compatible with polyradiculoneuropathy. By the end of the fourth week, the patient was discharged from the hospital under prescription of antihypertensive drugs and still being followed up by motor physical therapy. After 40 days of hospital discharge, the patient was orthostatic, walking-dependent for small distances and with pain sequels in the lower limbs. Five months later, residual sequels were still present with autonomous difficult scarvant gait. After 12 months, the gait patterns were regular; however, the speed and execution of upward and downward movements remained affected. Finally, the patient returned to her daily activities. Methods performed in this work using the placenta and fetal organs are described in Supplementary Material.