In this study, the S. clavata strain was isolated from the blood culture and urine (>100.00 CFU mL- ) of an immunosuppressed patient with B-cell acute lymphoblastic leukemia. In general, such cases are the usual profile and exhibit the risk factors of those who develop S. clavata-related infections. In Brazil, S. clavata had only been previously reported in 2016, isolated from a 6-year-old female patient with hemophagocytic lymphohistiocytosis. This case exhibited neutropenia and was treated with amphotericin B deoxycholate and voriconazole, but the outcome was death  . In our study, S. clavata was identified using MALDI-TOF and SARAMIS  from blood cultures and isolated colonies, and then confirmed with NGS of gDNA using bioinformatics tools. Our case was restricted to only one patient and any other cases or outbreaks were reported after his/her death.