Father, 46 years old, body weight 68 kg, height 176 cm and BMI 22 kg/m2. In the early years of his life he suffered from recurrent respiratory infections, diarrhoea, abdominal pain and aphthae on oral cavity mucosa, then at the age of 16 he was treated due to tuberculosis (similar pathological symptoms and tuberculosis in the medical history of his father). Due to abdominal pain, loose stools and weakness, at the age of 40 years he decided to exclude gluten from his diet (both his sons already followed a gluten-free diet). After about 2 weeks of the diet he noticed improvement in his general feeling and regression of abdominal pain and previously observed bad breath. The genotype examination for HLA-DQ2/DQ8 was negative, which rather allows exclusion of genetic susceptibility to celiac disease.
The patient on his own, without any arrangements, had serological tests performed: IgE specific for wheat, rye and gluten in class 0, total IgA and IgE concentration within normal limits and tTGA IgA < 0.6 U/ml. Serological testing performed in the course of a diet has no diagnostic significance and thus does not allow confirmation or exclusion of food allergy to gluten. The patient was informed about the need of provocation with small doses of gluten in the diet.