A 46-year-old woman presented with continuous abdominal pain for more than a month. There was no family history of gastrointestinal tumors. There was no sign of peritonitis, and no abnormal findings were detected from the laboratory studies performed at admission, such as serum electrocytes, TB-IFN, and the immune PHOMO check. The CT results were within normal limits (Fig.1). The EUS indicated a hypoechoic tumor with slightly heterogeneous internal echoes originating from the submucosal area located at the stomach antrum, measuring 1.3*1.0 cm with well-defined borders (Fig.2A BC). The tumor protruded into the cavity. Upon ESD, we could see a yellow oval tissue with a well-defined border that was similar to fat or pancreatic lesions (Fig.2D). Histopathologic analysis indicated an onion-skin-like concentric formation of the fibroblastic stroma and spindle cells with inflammatory cell infiltration, predominantly by numerous eosinophils (Fig.3A). Immunohistochemical examination showed that the cells were positive for CD34 (Fig.3B), Smooth Muscle Actin (SMA) (Fig.3C), and were negative for CD117 (Fig.3D), DOG-1 (Fig.3E), S100 (Fig.3F) and ALK (Fig.3G). The P53 labeling index was 1% (Fig.3H), whereas the Ki-67 labeling index was 5% in the spindle cells (Fig.3I). The histopathological and immunohistochemical findings were consistent with an IFP. By using an acid inhibitor and painkiller, the abdominal pain was not significantly improved, but was relieved after ESD. She is currently in clinical remission. Finally, we diagnosed the tumor as an IFP because the histopathological and immunohistochemical findings were the same.
Ethical approval: The research related to human use has been complied with all the relevant national regulations, institutional policies and in accordance the tenets of the Heisinki Declaration and has been approved by the Affiliated Hospital of Southwest Medical University review board.
Informed consent: Informed consent has been obtained from patient included in this study.