A 60-years-old man was diagnosed with IgG kappa multiple myeloma (MM) in 2002. He received induction therapy followed by autologous HCT with melphalan MAC in August 2002. He relapsed 15 months after auto-HCT. He received another induction followed by allo-HCT in 2004 after achieving deep remission. His conditioning was reduced intensity with fludarabine/TBI. In 2013 he had a biochemical relapse, so he was re-induced with bortezomib based therapy followed by donor lymphocyte infusion (DLI). He had another relapse in December 2019 and has been on dexamethasone 32 mg weekly since then. In May 2020, he developed fever and body aches after contact with a confirmed case of COVID-19, and he tested positive by PCR for SARS-Cov2 infection. He was admitted and treated symptomatically only and then discharged three days after admission after symptom-improvement. Repeat nasal SARS-Cov2 PCR on August 15, 2020, was negative, and his SARS-Cov2 total antibody test was reactive on August 16, 2020.