A 44-year-old man sustained a 55% total body surface area burn secondary to a gasoline fire. He required numerous rounds of excision and autografting and was discharged to inpatient rehabilitation on postburn day 45. Approximately 3 months postburn, he presented to clinic with a persistent area of hypertrophic granulation tissue overlying his left tibia at the site of a previous full-thickness skin excision and split-thickness skin graft. The lesion was found to be squamous cell carcinoma (SCC).
What are the predisposing factors and average time at presentation of a Marjolin's ulcer?
What are the histological findings?
How are these lesions diagnosed and treated?
What is the prognosis?