The female neonate was born after gestational age of 38 weeks and 2 days with an elective caesarian section due to an antenatal diagnosis of congenital omphalocele in the second trimester, with an Apgar score 8 at the 1st minute and 9 at the 5th. This firstborn neonate weighted 2.800 gr at birth and presented a giant omphalocele containing the whole liver and part of the large and small intestine (Figure 1). The rest of the physical examination was normal with no cardiovascular anomalies. The newborn was admitted to the neonatal intensive care unit and was supported with mechanical ventilation using sedation and muscle relaxation for the first 4 days of life. In the second postnatal day the patient underwent the first operation with excision of the hernia sac, complete reduction of the viscera into the peritoneal cavity, and abdominal wall closure without any traction, after identification and separation of the skin from the fascia and debridement of the margins. The early primary closure technique seemed successful and the neonate was in a stable condition postoperatively. An infection was noted on the 7th postoperative day due to colonization of a peripherally inserted central venous catheter with staphylococcus epidermidis. The neonate was dismissed from the pediatric surgery clinic after nursing for a month with no feeding or other problems.