Maybe the most influential work published by Paul Blocq and Georges Marinesco was an article published in 1893 (Figure 2). It depicted the case of a 38 years-old man, suffering from tuberculosis, who was admitted to the Charcot's neurological ward because he also displayed signs of unilateral Parkinsonism (primarily muscle rigidity and left side tremor). Jean-Baptiste Charcot, the son of Jean Martin Charcot, treated the patient and detailed his clinical evolution (Parent and Parent,). The autopsy showed the cause of death to be pulmonary complications of tuberculosis. While examining the brain, the investigators found a tubercle that destroyed the right substantia nigra: "Its limits in the peduncle were: in front, by the foot of the peduncle, behind by the superior cerebellar peduncle, inward by the fibers of the common oculomotorius nerve, and outward, until the elements of the medial lemniscus (Untere-Schleife). Summarizing, the tumor affected the substance of Soemmering. It is to be remarked that various elements of the protuberance, besides being displaced and compressed, were not destroyed, as it was proven by the absence of degeneration of the pyramids at the base, and of the cerebellar peduncle, at the top." (Blocq and Marinesco,).