Papilloma viruses are small DNA viruses that induce the hyperproliferation of epithelial cells. Approximately 70 different genotypes of human papilloma virus (HPV) have been isolated. Some HPV genotypes (e.g., 1, 2 4, and 7) have been associated with human benign squamous papillomas (warts and condylomas) and others (e.g., 16 and 18) have been associated with human neoplastic and preneoplastic lesions (DiPaolo, et al., 1993, Crit. Rev. Oncogen. 4:337-360).
HPV-16 has been associated with a variety of clinical conditions in both women and men. In women, HPV-16 is frequently associated with latent infections, benign and premalignant cervical lesions (dysplasias/CIN) and half of invasive cervical carcinomas. Cervical cancer, which kills at least 500,000 women worldwide each year, proceeds through progressive cellular changes from benign condylomata to high-grade dysplasias/CIN before developing into an invasive cancer. In men, HPV-16 is associated with subclinical macular or clinical papular lesions. Penile Bowenoic papulosis which resembles carcinoma in situ. Detection and treatment of these lesions costs over five billion health care dollars annually in the United States.
HPV-16 has been associated with over half of invasive cervical carcinomas worldwide and with many cell lines derived from cervical carcinomas. HPV-16 expression causes benign proliferation and efficiently immortalizes cultured human epithelial cells, including cervical keratinocytes (DiPaolo, et al., 1993, Crit. Rev. Oncogen. 4:337-360; Zur Hausen & de Villiers, 1994, Annu. Rev. Microbiol. 48:427-447; Schiffman, 1995, J. Natl. Cancer Inst. 87:1345-1347). Two HPV-16 genes, E6 and E7, and their gene products are required to immortalize a human keratinocytes and are a hallmark of cervical carcinoma (Hawley-Nelson et al., 1989, EMBO J. 8:3905-3910; Phelps et al., 1988, Cell 53:539-547; Viallet et al., 1994, Exp. Cell Res. 212:36-41; Yokoyama et al., Obstet. Gynecol. 83:197-204). The E6 and E7 proteins bind to other gene products (p53 and Rb tumor suppressors) to disrupt control of cell division and proliferation, leading to transformation (Scheffner et al., 1990, Cell 63:1129-1136; Zerfass et al., J Virol. 69:6389-6399)
Surgery is commonly used for treatment of high-grade lesions due to the lack of effective alternatives. Cervical laser ablation therapy, however, does not in the long term influence the natural history of cervical human papillomavirus-associated diseases in women. Interferons have not proved an effective antiviral or anticancer treatment. Chemotherapy (e.g., cisplatin, alone or combined with other chemotherapy agents such as 5FU) has generally not proved to be effective in treatment of many cervical cancers. Moreover, most chemotherapeutic agents are cytotoxic, leading to toxic side effects and the development of multiple drug resistance. Therefore, there is a need for reagents than can specifically inhibit the growth of HPV-associated tumor cells, while avoiding serious toxic reactions.
HPV-specific treatments in the form of cleavage of HPV-specific RNA with ribozymes and inhibition by HPV-specific antisense oligonucleotides have been suggested (PCT International Patent Application WO 95/31552; DiPaolo, et al., 1993, Crit. Rev. Oncogen. 4:337-360; Steele, et al., 1993, Cancer Res 53:2330; Storey, et al., 1991, Nuc. Acids Res. 19(15):4109). Ribozymes are small catalytic RNA molecules that can hybridize to and cleave a complementary RNA target (Cech, 1988. JAMA 260:3030-3034). Ribozymes having a "hairpin" motif have been found to be more efficient than the "hammerhead" motif (Hampel & Ttitz, 1989, Biochem. 28:4929-4933; Hampel, et al., 1990, Nuc. Acids Res. 18:299-304) and "hairpin" ribozymes have been used to cleave viral targets, including the human immunodeficiency virus (HIV-1) and HPV (Ojwang, et al., 1992, Proc. Natl. Acad. Sci. USA 89, 10802-10806; Yu, et al., 1993, Proc. Natl. Acad. Sci. USA 90:6340-6344; PCT International Patent Application WO 95/31552).
Antisense RNA and oligonucleotides hybridize to complementary mRNA, thus blocking translation and promoting the activity of endogenous RNase H to cleave the mRNA (Walder, 1988, Genes Dev. 2:502-504; Cohen, 1991, Antisense Res. Dev. 1:191-193). Although antisense RNA and oligonucleotides should be specific for their target sequence, nonspecific toxicity has been observed (Henry et al., 1997, Toxicol. 116:77-88; Henry et al., 1997, Anticancer Drug Des. 12:1-14). First-generation antisense phosphorothioates, whose nucleotide backbones carry sulfur atoms to slow intracellular degradation were often ineffective because of inability to enter cells or to complement the target mRNA, but improved second generation phosphorothioate antisense therapies, referred to as "mixed backbone oligonucleotides" and "end-modified chimerics" that carry 2'-O-methylribonucleoside moieties have proven effective in clinical trials (Monia et al., 1996, Nature Medicine 6:668-675; Roush, 1997, Science 276:1192-1193; Agrawal et al., 1997, Proc. Natl. Acad. Sci. USA 94:2620-2625; Agrawal, 1996, TIBTECH 14:3-14).
Antisense inhibition of HPV-18 E6 and E7 expression in cell lines (C4-1 and HeLa) resulted in a significant decrease in growth rate with continuous addition of oligonucleotide (Steele, et al., 1993, Cancer Res. 53:2330-2337). Similar results have been observed in cells transfected with recombinant vectors (von Knebel Doeberitz & Grissmann, 1987, Hamatol. Bluttransfus. 31:377-279; Hamada et al., 1996, Gynecol. Oncol. 63:219-227).
The present invention discloses oligonucleotide sequences and methods of antisense therapy using antisense oligonucleotides defined by selected HPV-16 complementary sequences.


President Trump at a rally in Pennsylvania last night. Photo: Brendan Smialowski/AFP/Getty Images

At his rally last night, President Trump’s characteristic threats of vengeance against his enemies took an especially chilling turn. “There was treason!” he announced, summarizing the investigation into the Mueller probe. The crowd began chanting, “Lock them up! Lock them up!”

Trump initially returned to his prepared text, itself a creepily ethno-nationalist paean to his narrow Electoral College win. “You reclaimed your destiny, you defended your dignity, and you took back your country,” he read, in a passage that probably sounded better in the original German. But the “Lock them up!” chants persisted, and, with his showman’s gift for timing, Trump turned back to his audience and paused as the chants increased, then theatrically relented to the demands of the crowd that he had stoked. “We have a great new attorney general who will give it a very fair look, very fair look,” he promised.

It is difficult to fully describe what Trump conveyed in this line without watching the video. As Trump said “very fair,” he wore an arch expression. Trump of course does not use “fair” in anything like the dictionary definition of the term. Trump’s notion of “fairness” is purely positional, revolving entirely around his own self-interest. With his expression, Trump — unusual for him — brought the crowd in on the joke. “Very fair” was a punch line.

Trump’s notion of a “fair” attorney general, as he has stated many times, is one who loyally protects the president’s political interests. His frequent expressions of confidence in William Barr are therefore an important indicator. Barr conspicuously refused to answer a question about whether he had been ordered to investigate anybody, then announced a new, third, investigation into the origins of the Russia probe. Barr has also repeatedly prejudged the outcome of that probe in public. Trump “has told close confidants that he ‘finally’ had ‘my attorney general,’ according to two Republicans close to the White House,” reports the Associated Press. Every indicator suggests Trump believes, correctly or otherwise, that his attorney general shares his peculiar, mob-family sense of fairness.

In a pre-Trumpian world, this sequence of events would set off a political crisis. In the surreal landscape we inhabit, it barely registers. But it is worth noting that Trump continues to commit impeachable offenses at an unprecedented pace. Last night’s threats to make good on his “lock them up” promises are merely one more in another recent flurry. The space between Trump’s long-standing authoritarian rhetoric and the deployment of his powers of office is slowly collapsing on several fronts.

Consider some of the events of recent days. Sunday, the New York Times revealed that Deutsche Bank’s internal investigators raised concerns that the portfolios of Trump and his son-in-law Jared Kushner involved money laundering. Trump is suing Deutsche Bank to block it from complying with congressional investigators. The notion that the president is entitled to engage in red-flagged dealings with money launderers, and conceal it from Congress and the public, is a wild transgression of transparency norms.

The same day, the Times reported Trump is preparing pardons for several American war criminals. Trump has long fantasized about war crimes and human-rights violations as part of his idealized military, from repeating a fantasized historical account of General Pershing shooting Muslims with bullets dipped in pig’s blood to proposing that the United States seize Iraqi oil as spoils of war. His prospective pardoning of war criminals are steps toward institutionalizing this vision as de facto law.

Yesterday, the Washington Post reported that Michael Cohen told a closed House panel that Trump’s lawyer, Jay Sekulow, encouraged him to lie to Congress in 2017. Cohen’s lie concerned his handling of a deal to build a Trump-branded tower in Moscow. The subject of the lie is itself a massive scandal: Vladimir Putin, who habitually corrupts foreign politicians with bribes disguised as lucrative deals, was dangling a contract worth several hundred million dollars, with no financial risk or downside to Trump.

Cohen has testified that Trump encouraged him to lie by repeating, in his characteristic mobster code — “There’s no Russia” — a cover story both men knew to be false. (Trump of course signed the letter of intent for the Moscow Project.) The new report shows that Sekulow was involved in crafting his false testimony, and that, far from the president’s lawyer freelance ordering perjury, Cohen understood Trump to be working through Sekulow:

Hmm. Trump better hope that HPSCI doesn't find a way to get Sekulow's testimony. pic.twitter.com/vAKUGjQJqZ — emptywheel (@emptywheel) May 21, 2019

The new disclosure fleshes out more evidence that the president suborned perjury to conceal evidence that he was deeply compromised by Russia during the campaign.

Also yesterday, former White House Counsel Don McGahn refused to appear at a House hearing to testify to yet another serious presidential crime. According to the Mueller report, Trump ordered McGahn to tell Deputy Attorney General Rod Rosenstein to fire Mueller, an order McGahn refused. Trump later told McGahn to falsely deny Trump had ever told him this.

Trump has publicly insisted none of this has happened, a denial that makes McGahn’s testimony highly pertinent. There is no basis for refusing to let McGahn testify. It’s not executive privilege, a right McGahn already waived by discussing it with Mueller. Instead, the White House is advancing the novel and extreme argument that Congress can never compel testimony from a senior White House official. That precedent, if accepted, would negate vast swathes of Congress’s long-standing investigative powers.

What’s more, Trump is backstopping his demand with financial blackmail. The AP reports that “Trump has mused about instructing Republicans to cease dealing with the firm” currently employing McGahn, which relies on Republican connections for its business. So Trump, in short, is using financial blackmail in support of a fallacious legal argument in order to cover up a clear instance of obstruction of justice — a seamless garment of corruption.

What cynics had waved off as Trump’s cartoonish musings is slowly seeping its way into sanctioned government policy. The question of whether or not to impeach Trump has attached itself to the discrete drama of the Mueller report, which contains a large cache of Trumpian misconduct. But the misconduct is also an ongoing process with no clear endpoint. The impeachable offenses just keep coming.


Generalized extended Navier-Stokes theory: multiscale spin relaxation in molecular fluids.
This paper studies the relaxation of the molecular spin angular velocity in the framework of generalized extended Navier-Stokes theory. Using molecular dynamics simulations, it is shown that for uncharged diatomic molecules the relaxation time decreases with increasing molecular moment of inertia per unit mass. In the regime of large moment of inertia the fast relaxation is wave-vector independent and dominated by the coupling between spin and the fluid streaming velocity, whereas for small inertia the relaxation is slow and spin diffusion plays a significant role. The fast wave-vector-independent relaxation is also observed for highly packed systems. The transverse and longitudinal spin modes have, to a good approximation, identical relaxation, indicating that the longitudinal and transverse spin viscosities have same value. The relaxation is also shown to be isomorphic invariant. Finally, the effect of the coupling in the zero frequency and wave-vector limit is quantified by a characteristic length scale; if the system dimension is comparable to this length the coupling must be included into the fluid dynamical description. It is found that the length scale is independent of moment of inertia but dependent on the state point.


/* <editor-fold desc="MIT License">

Copyright(c) 2018 Robert Osfield

Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software.

THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.

</editor-fold> */

#include <vsg/io/Options.h>
#include <vsg/state/DescriptorBuffer.h>
#include <vsg/traversals/CompileTraversal.h>
#include <vsg/vk/CommandBuffer.h>

using namespace vsg;

/////////////////////////////////////////////////////////////////////////////////////////
//
// DescriptorBuffer
//
DescriptorBuffer::DescriptorBuffer() :
    Inherit(0, 0, VK_DESCRIPTOR_TYPE_UNIFORM_BUFFER)
{
}

DescriptorBuffer::DescriptorBuffer(ref_ptr<Data> data, uint32_t in_dstBinding, uint32_t in_dstArrayElement, VkDescriptorType in_descriptorType) :
    Inherit(in_dstBinding, in_dstArrayElement, in_descriptorType)
{
    if (data)
    {
        bufferInfoList.emplace_back(nullptr, 0, 0, data);
    }
}

DescriptorBuffer::DescriptorBuffer(const DataList& dataList, uint32_t in_dstBinding, uint32_t in_dstArrayElement, VkDescriptorType in_descriptorType) :
    Inherit(in_dstBinding, in_dstArrayElement, in_descriptorType)
{
    bufferInfoList.reserve(dataList.size());
    for (auto& data : dataList)
    {
        bufferInfoList.emplace_back(nullptr, 0, 0, data);
    }
}

DescriptorBuffer::DescriptorBuffer(const BufferInfoList& in_bufferInfoList, uint32_t in_dstBinding, uint32_t in_dstArrayElement, VkDescriptorType in_descriptorType) :
    Inherit(in_dstBinding, in_dstArrayElement, in_descriptorType),
    bufferInfoList(in_bufferInfoList)
{
}

DescriptorBuffer::~DescriptorBuffer()
{
    for (auto& bufferInfo : bufferInfoList)
    {
        bufferInfo.release();
    }
}

void DescriptorBuffer::read(Input& input)
{
    for (auto& bufferInfo : bufferInfoList)
    {
        bufferInfo.release();
    }

    Descriptor::read(input);

    bufferInfoList.resize(input.readValue<uint32_t>("NumData"));
    for (auto& bufferInfo : bufferInfoList)
    {
        bufferInfo.buffer = nullptr;
        bufferInfo.offset = 0;
        bufferInfo.range = 0;
        input.readObject("Data", bufferInfo.data);
    }
}

void DescriptorBuffer::write(Output& output) const
{
    Descriptor::write(output);

    output.writeValue<uint32_t>("NumData", bufferInfoList.size());
    for (auto& bufferInfo : bufferInfoList)
    {
        output.writeObject("Data", bufferInfo.data.get());
    }
}

void DescriptorBuffer::compile(Context& context)
{
    VkBufferUsageFlags bufferUsageFlags = VK_BUFFER_USAGE_UNIFORM_BUFFER_BIT;

    bool requiresAssingmentOfBuffers = false;
    for (auto& bufferInfo : bufferInfoList)
    {
        if (bufferInfo.buffer == nullptr) requiresAssingmentOfBuffers = true;
    }

    if (requiresAssingmentOfBuffers)
    {
        VkDeviceSize alignment = 4;
        if (bufferUsageFlags == VK_BUFFER_USAGE_UNIFORM_BUFFER_BIT) alignment = context.device->getPhysicalDevice()->getProperties().limits.minUniformBufferOffsetAlignment;

        VkDeviceSize totalSize = 0;
        VkDeviceSize offset = 0;

        for (auto& bufferInfo : bufferInfoList)
        {
            if (bufferInfo.data)
            {
                bufferInfo.offset = offset;
                bufferInfo.range = bufferInfo.data->dataSize();

                totalSize = offset + bufferInfo.range;
                offset = (alignment == 1 || (totalSize % alignment) == 0) ? totalSize : ((totalSize / alignment) + 1) * alignment;
            }
        }

        auto buffer = vsg::Buffer::create(totalSize, bufferUsageFlags, VK_SHARING_MODE_EXCLUSIVE);

        for (auto& bufferInfo : bufferInfoList)
        {
            if (!bufferInfo.buffer) bufferInfo.buffer = buffer;
        }
    }

    bool needToCopyDataToBuffer = false;
    for (auto& bufferInfo : bufferInfoList)
    {
        if (bufferInfo.buffer->compile(context.device)) needToCopyDataToBuffer = true;
    }

    if (needToCopyDataToBuffer)
    {
        for (auto& bufferInfo : bufferInfoList)
        {
            bufferInfo.copyDataToBuffer(context.deviceID);
        }
    }
}

void DescriptorBuffer::assignTo(Context& context, VkWriteDescriptorSet& wds) const
{
    Descriptor::assignTo(context, wds);

    auto pBufferInfo = context.scratchMemory->allocate<VkDescriptorBufferInfo>(bufferInfoList.size());
    wds.descriptorCount = static_cast<uint32_t>(bufferInfoList.size());
    wds.pBufferInfo = pBufferInfo;

    // convert from VSG to Vk
    for (size_t i = 0; i < bufferInfoList.size(); ++i)
    {
        auto& data = bufferInfoList[i];
        VkDescriptorBufferInfo& info = pBufferInfo[i];
        info.buffer = data.buffer->vk(context.deviceID);
        info.offset = data.offset;
        info.range = data.range;
    }
}

uint32_t DescriptorBuffer::getNumDescriptors() const
{
    return static_cast<uint32_t>(bufferInfoList.size());
}

void DescriptorBuffer::copyDataListToBuffers()
{
    for (auto& bufferInfo : bufferInfoList)
    {
        bufferInfo.copyDataToBuffer();
    }
}


Q:

How to use Option[T] to handle null value well in scala?

Java code:
public static Connection connection = null;
public static void main(String[] args) {
    if(connection == null){
        connection = ConnectionFactory.createConnection(conf);
    }
    //using connection object to do something
}

converting to Scala code:
someone tell me use Option[T] to handle null value, but I don't how to use Option[T] well, I think it very troublesome.
Scala code:
    var connOpt: Option[Connection] = None
    def main(args: Array[String]) {
        //check `connOpt` Option
        connOpt match {
            case Some(connection) => { /* using `connection` to do something-----code1  */    }
            case _ => {
                val connection = ConnectionFactory.createConnection()
                connOpt = Option(connection)
                // using `connection` to do something------code2
                }
        }
    }

you can see scala code.

I need check connOpt always when I need use connOpt.
code1 and code2 is the same code, I need write two times, I know I can use function to package code1 or code2, but it's very troublesome.

How to handle this case?

A:

I think you can use the 'fold' method to do what you want like this
var connOpt:Option[Connection] = None
def main(args: Array[String]) {
    val connection = connOpt.fold(ConnectionFactory.createConnection()){conn => conn}
    //using connection object to do something
}

The logic of code mentioned above is the same as your java code that does not write the 'code1' and 'code2' two times.
Using the following example to explain the usage of 'fold'
obj.fold{/*the obj is null, you can return the value you want*/}{a => a
/*if the obj is Some(value), the 'a' is just the 'value'*/
}

Good luck with you


Working once again with Dan Deleeuw and Jen Underdahl at Marvel, we were excited to tackle a year-and-a-half production cycle and provide VFX solutions for installments 3 and 4 of the Avengers saga. Cantina was tasked with solving a handful of story concepts ranging from Shuri’s operation on Vision in Avengers: Infinity War to Tony inventing time travel via the mobius strip in Avengers: Endgame. We reprised our role as HUD designers and VFX artists for Hulkbuster, Warmachine, and Tony’s new MK85 bleeding edge suit.


Q:

datatype for math calculations like BMR function

I'm writing a BMR function, should I be using a decimal type as my return value for highest percision? (C#)

A:

Assuming you mean the basal metabolic rate, I'd use double. We're talking about natural quantities here which don't have discrete values - we might say that something weighs 10.25kg for example, but that's already an estimate. It's not like currency, where $10.25 is exactly that amount of money.
I reckon a reasonable rule of thumb is "double for science, decimal for finance" - but it's not an absolute rule, obviously.


--TEST--
Assigning to a non-existent static property
--FILE--
<?php
Class C {}
C::$p = 1;
?>
--EXPECTF--
Fatal error: Access to undeclared static property: C::$p in %s on line 3


Abnormalities in primary granule exocytosis in neutrophils from Type I diabetic patients with nephropathy.
Microalbuminuria in Type I diabetes involves a cell membrane abnormality and is associated with a large increase in cardiovascular risk. The hypothesis that the membrane abnormality alters granule exocytosis in neutrophils, which could contribute to the increased incidence of cardiovascular disease, was investigated. PMA-stimulated expression of CD11b and CD69 on neutrophils from normal controls (NC), long-term uncomplicated Type I diabetic control patients (DC) and diabetic nephropathy patients (DN) was determined by fluorescence activated cell scanning. Neutrophils from DN were faster than neutrophils from either NC or DC to exocytose primary granules with CD69 following initial expression of the adhesion molecule CD11b. However, a larger proportion of neutrophils from DN failed to withdraw CD11b from the cell membrane after 90 min incubation. The protein kinase C (PKC) inhibitor, bisindolylmaleimide (BIM), showed that a larger proportion of neutrophils from DN, compared with DC or NC, exocytosed primary granules independent of PKC. The calpain inhibitor, E64d, showed that a larger proportion of neutrophils from both groups of diabetic patients, compared with NC, exocytosed primary granules independent of calpain. Cytoskeletal disruption with cytochalasin D had an effect on CD11b and CD69 exocytosis similar to that of BIM and E64d. The pathways controlling granule exocytosis in neutrophils from diabetic patients are abnormal. A change characteristic of DN causes rapid exocytosis of primary granules, and also causes the adhesion molecule CD11b to persist on an increased proportion of neutrophils. This will make an important contribution to increased vascular damage in these patients.


Q:

Chef - Foodcritic FC019 false positive

We are using foodcritic to lint all of our chef cookbooks and have recently come across this problem.
Using foodcritic 6.3.0
Output of foodcritic . is
FC019: Access node attributes in a consistent manner: ./recipes/configure_topics.rb:6
FC019: Access node attributes in a consistent manner: ./recipes/configure_topics.rb:10
FC019: Access node attributes in a consistent manner: ./recipes/configure_topics.rb:12

configure_topics.rb has the following contents
#
# Cookbook Name:: kafka
# Recipe:: configure_topics
#

node['kafka']['topics'].each do |topic, flag|
    bash "create #{topic} topic" do
        user "root"
        code <<-EOH
        /opt/kafka/bin/kafka-topics.sh --zookeeper #{node['kafka']['broker']['zookeeper']['connect']} --create --topic #{topic} --partitions 1 --replication-factor 1
        EOH
        not_if "/opt/kafka/bin/kafka-topics.sh --zookeeper #{node['kafka']['broker']['zookeeper']['connect']} --list | grep #{topic}"
    end
end

As seen in the code, the symbol method of accessing attributes is not used, so FC019 should not be shown here, correct?
I've opened the following issue with foodcritic on their github here, however I haven't heard back.
Is there anything I can do to change my recipe so it doesn't throw these warnings in the interim? Thanks.

A:

As @KarenB aluded to, the check is against the entire cookbook. You are likely using one of the other formats for everything else in the cookbook, so those were flagged as the least used and thus an error.


Disney’s new animated film stars Fil-Canadian actress Cassie Steele

Cassie Steele (Raya) and Awkwafina (Sisu, the Last Dragon), were presented as the leads of Disney’s new movie. Credits to Walt Disney Animation Studios.

Disney’s new animated film, Raya and the Last Dragon, will star Filipino-Canadian actress Cassandra “Cassie” Steele in the title role.

Walt Disney Animation Studios announced the upcoming movie and presented the two lead stars, Cassie Steele (Raya) and Crazy Rich Asians star Awkwafina (Sisu, the Last Dragon), on August 24 at the Disney D23 Expo 2019 Fan Club event in California.

Cassie Steele went on social media to say how she was “So grateful to be working alongside the incredibly talented and hilarious @awkwafina Paul Briggs @_paul_briggs_ and Dean Wellins (Big Hero 6, Frozen) are directing with Moana’s Osnat Shurer producing. The incredible @adeleblim (Crazy Rich Asians) has written this beautiful masterpiece.”

The Asian-themed animated film tells the story of Raya, a lone warrior from the fantasy kingdom of Kumandra who teams up with a crew of misfits in her quest to find the Last Dragon and bring light and unity back to their world.

Raya meets Sisu when she is in human form when she is “not the dragon hero Raya is looking for,” Steele said at the D23 stage.

Disney describes Raya and the Last Dragon as a film that explores themes of community and hope and is inspired by the beautiful and diverse cultures of Southeast Asia.

Cassie Steele traces her parental heritage to a Filipina mother and a British father. She has a portfolio of several television credits and hit shows and won a Young Artist Award for Best Ensemble Actor in a TV Series. Steele is also an accomplished singer who has released music albums.

Cassie Steele will be heard as the voice of the lead character Raya and the Last Dragon which opens in U.S. theaters on November 25, 2020.

Two of Disney’s hit animated movies, Mulan and Aladdin, featured the singing voice of Filipina international music star Lea Salonga.

Angie is a self-confessed reformed news critic who vows she has finally found infinite value in delivering the good news. She teaches students of all ages how to make the important interesting for audiences across media platforms.

Good News Pilipinas! TV

Every moment spent with your loved ones is an opportunity to make them feel how much they matter. Create more memories—go on that dream vacation, catch a movie, or simply spend the day at home playing silly games with your children. Discover your next happy family story when you use your HSBC Platinum Visa Credit Card.


To tell you the truth, the concept of biofeedback has been around in medicine for a very long time. So there is nothing new with biofeedback. What is relatively fresh, is the biofeedback therapy. Ever since the inception of homeostasis in 1885, the concept of monitoring the body and treating physical and mental problems by voluntary control of physical aspects is pretty well known. It was in 1969 that the term "Biofeedback Therapy" came into existence.


Trouble logging in?We were forced to invalidate all account passwords. You will have to reset your password to login. If you have trouble resetting your password, please send us a message with as much helpful information as possible, such as your username and any email addresses you may have used to register. Whatever you do, please do not create a new account. That is not the right solution, and it is against our forum rules to own multiple accounts.

The post starter claimed that it is the PV version--can anyone verify it for me? Is it the real one, or is it just a re-mix?

link deleted--sorry forgot to read the rules first--we'll see in the future, I'll hold on to the file until it's been officially released.

PV version would make sense. It has new lyrics, but it doesn't sound fluid at all. (There are various changes in the audio that can be heard.)

Quote:

Originally Posted by Kaioshin_Sama

Oh that's not going to be good for what is destined to be a chart topper (I mean in the Popularity Sense the "Oh My God It's From Lucky Star BUY IT! BUY IT!, not the "Oh My God, This Song Is Very Well Composed And Sung Beautifully, Therefore I Will Buy It" sense).

This is much better than HHY where the full version was absolute crap. I seriously doubt being a week early will hurt the sales that much, if not help the sales because people aren't worried about a repeat of HHY. (Then again, it seemed the Japanese weren't too put off by the full version.) Heck, its bizzareness should boost sales.

Quote:

Originally Posted by Telliamed

I'm sure enough people will still want to buy it, if only to get the lyric sheet. (And how many will be disappointed to discover it's not a song about sausages?)

I would think by now everyone knows it is not about sausage.

Quote:

Originally Posted by MakubeX2

It will be a slap in the face for Oricon if this song manage to reach No.1.

How? Oricon is just a measure of how many cds are sold. That is all it is. It doesn't determine quality or popularity.

After the debacle with episode 3 versus episode 5's ending I've decided that if Kyoto Animation is going to play favourites with their series music I will do the same in kind. For that reason I'm putting the following songs on a protection list from the characters of Lucky Star:

Spoiler:

By Decree of Moi The Following Songs Are Now Hereby Off Limits For Lucky Star Karaoke

Howling from Darker Than Black
Uninstall from Bokurano
Tobe Gundamu from Mobile Suit Gundam
Colours from Code Geass
Yakusoku Wa Iranai from Tenkuu No Escaflowne.
Any Legend of The Galactic Heroes Song
Yuusha Ou Tanjou from King of Braves GaoGaiGar
Beyond The Time from Char's Counterattack
Any Eureka 7 Song
Radical Dreamer from Chrono Cross
Any City Hunter Theme
Any Further Jam Project Song
Rewrite from Full Metal Alchemist
Ushinawareta Yume o Motomete from Genesis Climber Mospeada
Trust You Forever from Mobile Fighter G Gundam
Tsuki No Mayu from Turn A Gundam
Any song from Gravitation
Eternal Wind from Gundam F91
Tough Boy and Ai Wo Tormodose from Hokuto No Ken
Any Song From Kimagure Orange Road
Cloud Age Symphony from Last Exile
Any Two Mixx Song From Gundam Wing
Any Macross song
Mazinger Z No Theme
Any Metal Armor Dragonar Song
Any Super Bestial Machine God Dancougar Song
Naked Flower and Hikari Sasuhou from Murder Princess
Any One Piece Song
Over! from Overman King Gainer
Pegasus Fantasy from Saint Seiya
Hemisphere and Yume No Tamago from Rahxephon
Shippu Xabungle from Sentou Mecha Xabungle
Fukatsu Ideon and Cosmos Sora Wo Kakeru Kete from Spacerunaway Ideon
Melos No Youni Lonely Way from SPT Layzner
The Winner, True Shining, Men of Destiny and Evergreen from Gundam 0083: Stardust Memory
Any Tekkaman Blade Song
Now or Never and True Blue from Tetsuwan Atom 2003
Ten Years After From The 08th MS Team
Any Song from Victory Gundam
Any song from Yu-Gi-Oh
Any Song From Zeta Gundam
Yuusha Raideen No Them from Yuusha Raideen

That is All.

So if any of these songs are sung and butchered the show gets a Game Penalty from me unless they do one of their own series songs in an off-key fashion, in which case I'm dropping my protection ring around these songs. This is about the only way I can square things regarding the inconsistencies in the shows ending bits.

Screw that protection list BS, I actually want them to sing City Hunter songs, You WA Shock or Heart of Madness, or Saint Seiya songs, or Space Adventure Cobra.

I don't care if you get a heart attack from it, but as a big time nostalgic I have the right to enjoy how they gonna sing it.

Hell, if they pull any Queen's songs, I'd die, of happiness. Not because they are LS or KyoAni characters but because someone in the anime world remembered how awesome were these songs.

I have rl friends who are as much of Hokuto no Ken fanboys as I am, who never heard or saw what is moé and want Konata to sing You WA Shock after hearing DBZ's OP.

Then there are the uber-otaku who will buy multiple copies just to boost the rankings.

And I'm expecting next week's episode will be filled with subliminal and superliminal advertisements for the single.

Hahaha very funny, paranoia and what not....

@Sheba: It's called Ai Wo Tormodose, You Wa Shock is just something they scream during the song.

@MakubeX2: Why would it be a slap in the face, it has people's "goddess" singing the opening theme from a relatively (?) popular show. It's meant to sell mostly on the back of name recognition (because if I weren't told who was singing it I would have assumed it was chattering monkey's), in fact I'd be surprised if it wasn't a chart topper. All they need is to have her name plastered on it, let people know its in stores and watch a flood of dreary eyed folk storm through the store, maybe a few ritual killings for the last disc and then count their money.

Personally I'm interested in hearing what the off vocal version of the song sounds like (actually no I'm not and if they have any musical taste they'll never ever subject us to it on a single disc).

It will be a slap in the face for Oricon if this song manage to reach No.1.

Why?! a) Oricon is reportedly under investigation for being "rigged" and b) it's not like other anime theme songs haven't done well the chart before. For example, the No. 2 last week was the theme for "Kirarin Revolution."

I personally like the "surprises" in the Oricon chart. It's usually predictable to the point where I just need to look at the release dates and I can pencil in the Top 5. But once in a while you'll just get something out of the blue that does well on the charts for whatever reason.

BTW, does anyone have the lyrics (or an approximation thereof) for the full OP, yet? Japanese link is fine. Thanks in advance!

Something's been bothering me for a while now....just what exactly is the song used in the Ep06 Initial D parody? It has a sound characteristic of M.O.V.E. , the band which does the Initial D OPs and EDs, but this one isn't one of theirs, as far as I could see...

@Kenta
Been said before, but its Sera Fuku to Kikanjuu (Sailor Suit and Machine Gun), from the show of the same name. You can find the latest remake of it with English subs somewhere around the net, though I wouldn't bother since its one of the crappiest j-dramas I've ever had the displeasure of seeing. I can hazard a guess that the 80's movie is better, since the pacing was just horribly slow; thank God it was only 7 eps.

1. You can't isolate the vocals from the music, since the vocals are the music. It's candy-pop rap.

2. Bought for name recognition? How about every second #1 hit anywhere in the world?

3. As poetry, the words are better than most pop songs. Just complex and bizarre, both in meaning and in syntax.

4. I just listened to the full version, sans images, and there is no reason except anti-otaku prejudice for Oricon to be embarrassed about this song becoming #1, when I think of other songs that have hit that spot. This isn't like them, but it isn't worse, just totally different.

There are quite a few photos from the shops of Akihabara in this post on Akiba Blog about the campaign (click photos to enlarge). And here are photos (left) of a poster of the words, and (right) of a display saying the aim is to get the OP to #1 on Oricon and for this store (Toranoana main store) to sell more copies than any store in Japan. It also says they're taking orders for the first DVD:

I don't think the proponents of the campaign are thinking of profits for KyoAni (of course the shops are thinking of profits for themselves), I think it's more like supporting a sports team: you want the team you support to win, and this is an aspect of winning. I have to say, however, that I will be amazed if they get anywhere near #1. The SHnY OP only got to #5, and my sense is that that was a much bigger hit than this show. But we'll see by next Thursday.

__________________

Kimura Juri木村珠莉 Joined Tokyo Voice Actors' Co-op in 2011, did voice-overs for corporate presentations. Anime bit parts 2013-14. Stars in Shirobako as Miyamori, will star in Mikagura Gakuen Kumikyoku (spring). Enjoys music, looking at Buddha images, reading. Used to work at a bookstore. Says she is a maudlin drunk. Age unknown.Hashihime blog | Twitter@nakanokimi |

1. You can't isolate the vocals from the music, since the vocals are the music. It's candy-pop rap.

2. Bought for name recognition? How about every second #1 hit anywhere in the world?

3. As poetry, the words are better than most pop songs. Just complex and bizarre, both in meaning and in syntax.

4. I just listened to the full version, sans images, and there is no reason except anti-otaku prejudice for Oricon to be embarrassed about this song becoming #1, when I think of other songs that have hit that spot. This isn't like them, but it isn't worse, just totally different.

There are quite a few photos from the shops of Akihabara in this post on Akiba Blog about the campaign (click photos to enlarge). And here are photos (left) of a poster of the words, and (right) of a display saying the aim is to get the OP to #1 on Oricon and for this store (Toranoana main store) to sell more copies than any store in Japan. It also says they're taking orders for the first DVD:

I don't think the proponents of the campaign are thinking of profits for KyoAni (of course the shops are thinking of profits for themselves), I think it's more like supporting a sports team: you want the team you support to win, and this is an aspect of winning. I have to say, however, that I will be amazed if they get anywhere near #1. The SHnY OP only got to #5, and my sense is that that was a much bigger hit than this show. But we'll see by next Thursday.

I guess it's the same as campaigning for Oscar's. I'm going to be honest and say I'm not entirely sure what kind of standards Oricon has though, but actively campaigning somewhat cheapens things in my opinion, just like with the Oscars (Where it does have an impact). All I can say is I have no idea why Lucky Star is Akihabara's pick, I can understand the drive for profit, but I don't understand the reasoning behind picking a specific song to push. I don't think there's anything to be embarassed about at all other then perhaps an overly aggressive market approach. I would think the girls who sang the song would vastly prefer their song to achieve success on its own and land where it lands on the charts rather than have their song lifted by a massive campaigning effort. I would feel a bit guilty and unsure of myself if I were the artist. I wonder if people truly enjoyed my music or only bought it because they were told its what everybody else is doing. Then again I guess that #2 point is the answer again. This is one of the reasons I never paid attention to music all throughout middle school and high school, the popularity always trumped the musical effort itself and I just tended to avoid any and all conversations about music for that reason. I listened to what I liked, I didn't buy based on the artist or any industry push, but on my enjoyment of the song, and I stayed out of the loop. Still do.

Also the words are hysterical and unusual, but the tune is actually the key to a song for me. Tune and Beat are most important and they are only augmented by the lyrics. A song with a good tune will always be popular with me and even more so with good lyrics, but a song with good lyrics and an awful tune will never be a favourite. I think this song lands somewhere in the middle, funny lyrics and decent tune, but not playlist material. A lot of J-Pop falters in this regard be it both a crappy tune/beat and cliche lyrics or an alright tune/beat and crappy lyrics. Lucky Star is a probably but one step above in each category in my view.

Oh and popularity pushs have always been a huge huge turnoff for me. Having the same product advertised to me constantly from all directions is one of my pet peeves, so I tend to come on a little strong when one of these types of campaigns emerges. I just don't like that style of aggresive advertising at all. Sometimes I also wonder if those Lightspeed Brief ads from Futurama that advertise to you in your dreams are even a decade away let alone a millenium. That last sentence was a joke by the way (I hope).

I thought that was because there simply weren't enough copies made for it reach number one. It was sold out within hours, If I recall correctly.

I wonder if there was any trampling. Somehow I imagine fistfights breaking out and a grab fest with one guy triumphantly grabbing the CD with a ripped shirt and pants and taking off out of the store with a police officer and several others chasing after him, because he forgot to pay in his attempt to get away from the other buyers.

I wonder if there was any trampling. Somehow I imagine fistfights breaking out and a grab fest with one guy triumphantly grabbing the CD with a ripped shirt and pants and taking off out of the store with a police officer and several others chasing after him, because he forgot to pay in his attempt to get away from the other buyers.

kj1980 or someone will have to confirm this, but I believe Japanese public restraint even extends to otaku, so I don't expect there are many such scenes, which might be more common in North America. Japanese otaku may save their aggression for 2channel, lol.

__________________

Kimura Juri木村珠莉 Joined Tokyo Voice Actors' Co-op in 2011, did voice-overs for corporate presentations. Anime bit parts 2013-14. Stars in Shirobako as Miyamori, will star in Mikagura Gakuen Kumikyoku (spring). Enjoys music, looking at Buddha images, reading. Used to work at a bookstore. Says she is a maudlin drunk. Age unknown.Hashihime blog | Twitter@nakanokimi |


Skeletal maturation determined by cervical vertebrae development.
The aim of this study was to determine the validity of cervical vertebrae radiographic assessment to predict skeletal maturation. Left hand-wrist and lateral cephalometric radiographs of 958 Spanish children from 5 to 18 years of age were measured. On the left hand-wrist radiographs the classification of Grave and Brown was used to assess skeletal maturation. Cervical vertebrae maturation was evaluated with lateral cephalometric radiographs using the stages described by Lamparski and by Hassel and Farman. A new method to evaluate the cervical maturation by studying the changes in the concavity of the lower border, height, and shape of the vertebral body was created. Correlation coefficients were calculated to establish the relationship between skeletal maturation values obtained by the three classifications of vertebral and skeletal maturation measured at the wrist. All correlation values obtained were statistically significant (P < 0.001). The results suggest that this new method to determine skeletal maturation is very reliable. A simple method based on morphological characteristics of the cervical vertebral bodies to evaluate the maturation stage has been designed. In the population investigated, this method is as accurate as the Hassel and Farman classification and superior to the Lamparski classification. The morphological vertebral parameter best able to estimate the maturation is the concavity of the lower border of the body.


Use of Skype in interviews: the impact of the medium in a study of mental health nurses.
To discuss the use of Skype as a medium for undertaking semi-structured interviews. Internet-based research is becoming increasingly popular, as communication using the internet takes a bigger role in our working and personal lives. Technology such as Skype allows research encounters with people across geographical divides. The semi-structured interview is a social encounter with a set of norms and expectations for both parties ( Doody and Noonan 2012 ). Proceedings must take account of the social context of both semi-structured interviews per se, and that of internet mediated communication. The findings of the qualitative phase of a mixed-methods study are compared with other reports comparing the use of Skype with face-to-face and telephone interviews. This paper is a methodological discussion of the use of Skype as an online research methodology. Choosing Skype as a means of interviewing may affect the characteristics of participants and decisions about consent. Rapport, sensitivity and collaboration may be addressed differently in Skype interviews compared with face-to-face interviews. Skype offers researchers the opportunity to reach a geographical spread of participants more safely, cheaply and quickly than face-to-face meetings. Rapport, sensitivity and degrees of collaboration can be achieved using this medium. The use of Skype as a medium for semi-structured interview research is better understood. This paper contributes to the growing body of literature on the use of the internet as a medium for research by nurses.


BA/BA (Hons) Business Management

More and more employers require business management graduates who can join their company and hit the ground running. This degree will give you both the theoretical business knowledge and – crucially – the practical experience you need to make your professional mark from day one. You’ll also have the opportunity to study abroad*

Let’s talk business. When you study for a degree in business management at QMU you’ll gain a deep understanding of the nature and core functions of businesses. How do successful companies manage their resources? What’s the best way to make an organisation environmentally sustainable? What marks out a successful entrepreneur? You can study a broad business management degree or (after two years of general study) decide to focus your learning on the enterprise, finance or marketing elements of business management.

See the foot of the page for some student case studies/ staff profiles

Why QMU?

Placements give you the optimum balance of practical and theoretical learning.

Smaller class sizes mean you’ll get close support and guidance from staff who get to know you.

Graduate with a range of transferable business skills which are highly sought after by employers.

Tailor your degree in Years Three and Four and study business management with another subject – enterprise, finance or marketing – and make your skills stand out.

About the course

Let’s talk business. When you study for a degree in business management at QMU you’ll gain a deep understanding of the nature and core functions of businesses. How do successful companies manage their resources? What’s the best way to make an organisation environmentally sustainable? What marks out a successful entrepreneur? You can study a broad business management degree or (after two years of general study) decide to focus your learning on the enterprise, finance or marketing elements of business management.

People do business with people. If you have first-class management skills and practical expertise, people are going to want to be in business with you. The best companies will covet you. That’s why our business management options are designed to give you the knowledge and skills that you need to thrive as a business leader and manager in the fast-moving marketplaces of tomorrow.

All students enrol on the broad business management degree for Years One and Two. In these two years you’ll build a strong foundation in core business management areas – marketing, economics, finance, human resource management, entrepreneurship, digital business and law.

In Year Three you’ll choose which of the four named routes you wish to specialise toward. You can study for a broad business management degree or focus on one particular area such as enterprise, finance or marketing. This will allow you to graduate with a specialist award, for example in BA (Hons) Business Management with Enterprise.

Whichever business management path you take, you’ll be equipped with the skills employers are looking for – negotiation, project management, problem solving, critical thinking and team working.

Your practical business expertise will be honed by placements, guest speakers from the business world, business projects and the creation of your own business plan. You’ll also have the opportunity (subject to availability) in Years Two or Three to study for one semester at a university overseas in North America, Canada, Hong Kong, Europe, New Zealand or Australia.

Structure

You can opt to study for an honours degree over four years or an ordinary degree over three years. You will complete a range of modules each year as outlined.

Teaching, learning and assessment

You will be taught in lectures, seminars and practical workshops. Outside these formally timetabled sessions you will be expected to continue learning through self-study. You will be assessed by a range of methods such as written exams, reports, poster presentations, business plans, live pitch, group presentations and negotiation role play. >>Click for more information on 'Learning, Teaching and Assessment' - Please note that this is information relating to entry in 2019. Information for 2020 entry is not yet available.

Modules

Year One

Year One is designed as an introductory year, which will not only introduce you to key subject matter in business but will allow you to develop the skills and learning techniques required at university level education.Modules are:

Introduction to Marketing

Introduction to Economics

Introduction to Business in Society

Introduction to Finance and Accounting

Introduction to Management

Entrepreneurship

Year Two

Operations Management

Business Law

Live Business Event

Human Resource Management

Digital Business and E-Commerce Management

Negotiation

Years Three and Four

From Year Three you can choose which pathway to specialise towards. Modules are tailored to each route – see below for more information.

Specialist Business Management degrees

BA/ BA (Hons) Business Management

Our Business Management course will give you a solid foundation in the core principles of business management including marketing, human resource management, finance, economics and operations management. Years Three and Four examine business themes at a more strategic level and you can choose three elective modules from a range of modules on offer. In Year Four, you will undertake a placement and a practical, business-focused piece of independent work in an area of your choice. Studying a broad business management degree will allow you more flexibility to take advantage of a wide range of career options open to graduates in this field.

Year Three modules

New Enterprise Creation

Research Methods and Skills

Organisational Behaviour

Project Management

Two Elective Modules

Year Four modules

Strategy as Practice

Placement

Critical Issues in International Management

One Elective Module

Dissertation or Business Project

BA (Hons) Business Management with Enterprise

Are you bubbling with new business ideas? Are you prepared to do the hard work that will make them a success? Our BA (Hons) Business Management with Enterprise will help you finesse your entrepreneurial talents. In Years Three and Four, you can pick the modules best suited to your passion for enterprise. Year Four will probably be a particular highlight for you, as you’ll go on a live business placement and take the reins of an original, enterprise-focused piece of independent work. By the end of the course you’ll have broadened your career options and gained a solid foundation in the core principles of business management.

Year Three modules

New Enterprise Creation

Research Methods and Skills

One Elective Module

Organisational Behaviour

Project Management

Entrepreneurial Finance

Year Four modules

Strategy as Practice

Placement

Critical Issues in International Management

Critical Issues in SME and Family Business

Dissertation or Business Project

BA (Hons) Business Management with Finance

At the heart of every successful business is an accomplished Finance team. Our BA (Hons) Business Management with Finance is a specialist finance pathway that will give you the contemporary theory and practice you need to carve a career in business finance and management. In Years Three and Four modules will be tailored to your chosen route in finance. In addition, in Year Four you will undertake a finance placement and a practical, finance-based piece of independent work to develop your finance expertise in a relevant business context. The route is designed to increase your career options by also providing you with a solid foundation in core principles of business management. This route is fully accredited by the Chartered Institute of Management Accountants (CIMA), so you know that we’ll support your learning and ensure your professional development.

Year Three modules

New Enterprise Creation

Research Methods and Skills

Financial Markets and Institutions

Organisational Behaviour

Project Management

Entrepreneurial Finance

Year Four modules

Strategy as Practice

Placement

Corporate Finance

Financial Risk Management

Dissertation or Finance Project

BA (Hons) Business Management with Marketing

What makes customers buy from a business? How can self-promotion make a company more profitable? On our BA (Hons) Business Management with Marketing you’ll develop a specialised understanding of marketing theory and practice, while honing your core business management skills. In Years Three and Four you will take modules that focus your marketing studies further. In addition, in Year Four you will undertake a marketing placement and a practical piece of independent work to develop your marketing expertise in a relevant business context. The route is designed to increase your career options by also providing you with a solid foundation in core principles of business management.

Year Three modules

New Enterprise Creation

Research Methods and Skills

Experiential Marketing and Consumer Behaviour

Organisational Behaviour

Project Management/ Advertising and Marketing Communications

Year Four modules

Strategy as Practice

Placement

Critical Issues in International Marketing

Strategic Marketing Management

Dissertation or Business Project

The modules listed here are correct at time of posting (Feb 2019) but may differ slightly to those offered in 2020. Please check the website for any updates.

Placements

You will complete a four-week placement in Year Four. Students are responsible for sourcing a placement host organisation, which can be in the UK or abroad. To help with the process, we hold a speed interview event on campus to match hosts offering placements with students.

Please note that exchange opportunities are subject to availability. In addition, please note that where exchange opportunities are arranged in the EU, Erasmus+ funding is available subject to the UK remaining in the Erasmus+ scheme.

Careers

This is a degree that works. In general management, marketing, sales management, logistics, financial services, operations management and human resources management, our graduates are proving their worth to companies in the UK and internationally. Graduates have also set up their own businesses or taken their learning even further as postgraduate students.

Entry requirements

Scottish Higher: Standard BBBC, Minimum: BCCC

A Level: BCC

Irish Leaving Certificate: H2 H3 H3 H3

International Baccalaureate: 28 points

International: IELTS of 6.0 with no element lower than 5.5

Required subjects: Maths and English at Nat 5/GCSE.

Mature/Access: Related Access course – see our website at www.qmu.ac.uk/college-qualifications. We welcome applications from mature students with other relevant qualifications and/or experience.

Special Information for EU Applicants: Previously EU students have had the cost of their tuition fees met by the Scottish Government. At the point of publication there is no information on whether this arrangement will continue for students starting their studies in 20/21. Updates will be posted on the QMU website when available.

A Student Story - more at foot of page

Stephanie da Costa - BA (Hons) Business Management
"Over the next three years I shall rotate to different parts of Capita Asset Services, one of the ten divisions that make up Capita. My first placement began in October 2015 with the project management team in Shareholder Solutions. Not only have I been given responsibility for a number of high profile projects and smaller projects, I am also getting project management training."
read my story...


Lifetime Risk of Stroke and Coronary Heart Disease Deaths According to Blood Pressure Level: EPOCH-JAPAN (Evidence for Cardiovascular Prevention From Observational Cohorts in Japan)
Lifetime risk (LTR) provides an absolute risk assessment during the remainder of one’s life. Few studies have focused on the LTRs of stroke and coronary heart disease (CHD), categorized by fine blood pressure in Asian populations. We aimed to assess it using a large database of a meta-analysis with the individual participant data. The present metaanalysis included 107 737 Japanese (42.4% men; mean age, 55.1 years) from 13 cohorts. During the mean follow-up of 15.2±5.3 years (1 559 136 person-years), 1922 died from stroke and 913 from CHD. We estimated risks after adjusting for competing risk of death other than the outcome of interest. The 10-year risk of stroke and CHD deaths at index age of 35 years was ≤1.9% and ≤0.3%, respectively. The LTRs of stroke death at the index age of 35 years (men/women) were 6.1%/4.8% for optimal, 5.7%/6.3% for normal, and 6.6%/6.0% for high-normal blood pressure groups, and 9.1%/7.9% for grade 1, 14.5%/10.3% for grade 2, and 14.6%/14.3% for grade 3 hypertension groups. The LTRs of CHD death similarly elevated with an increase in blood pressure but were lower (≤7.2%) than those of stroke death. In conclusion, blood pressure was clearly associated with an elevated LTR of stroke or CHD death, although the LTR of CHD death was one-half of that of stroke death in an Asian population. These results would help young people with hypertension to adopt a healthy lifestyle or start antihypertensive therapy early.


Special Teams Coordinator Bobby April

On what factors help players contribute successfully on special teams: "Once you’re at a certain level, you have to have ability obviously to get to this level, and you have to have certain qualifications to play in this game physically. Once you’re in, I think attitude is everything –offense, defense, and I think particularly special teams. I’ve mentioned this before that there are obstacles to overcome in having the incentive to play in that area. It really takes a tough, young scrapper and really competitive and team guy to play well. I don’t think that is the reason that we’re playing poorly, but I think there have been some missteps in training them and maybe motivating them. Definitely your mental talent and toughness attributes to most of your success in this deal."

On the team’s kickoff coverage against the New York Giants: "Obviously it was very poor. It looked poorly conceived, poorly coached, and poorly executed. I’m responsible for all of those. I have to draw on all of the resources that I have as a coach and put them into play, and then resurrect us from these ashes."

On the drop-off in talent from a special teams prospective with injuries to S Colt Anderson and LB Akeem Jordan: "Certainly those guys are good players and they make most of our plays, but there should not be. Those guys are obviously, if they are dressed, going to be on those units. They would replace at least two players. That’s not the reason we did poorly. I think, in that instance, we were poorly prepared and I have to take responsibility for it. I have to do a better job."

On whether it is individual breakdowns or the scheme that has been causing problems: "Not really, no. The kickoff scheme is – you can trick them and you can fool them. Pretty much where I say I needed to do a better job is more than a reflection of Wednesday, Thursday, Friday practices and then Saturday’s review. It’s more long term. No matter what scheme you use, it ultimately comes down to when the bell rings and one guy comes out of one corner and one guy comes out of the other corner. The guy who is more prepared and more technically savvy is going to win. I don’t think if we would have kicked it a little more left or kicked it a little more right, should we elude this guy - all of those give you a greater probability. At times, those things don’t always work either. I just think that the preparation and long term preparation - I misjudged some things and need to do a better job of preparing the guys to whoop a guy when the bell rings."

On whether he had concerns about the kickoff coverage unit going into the game: "I go into every game, whether we are playing good or not, concerned about making sure we get everything done. Up until the game is over, I’m talking to the guys or doing whatever we can do to make something better. I wasn’t any more concerned against the Giants than I was against Cleveland or anybody else, although I will say the Giants are very good in that area and a lot of areas. So is (Cleveland returner Josh) Cribbs. Any more concern last week than this week? You’re always generally concerned regardless of who the opponent is."

On his discussion with head coach Andy Reid on Monday about the overall state of special teams: "We looked at the best way to maximize our play. He could’ve been (mad). Maybe he should’ve been. He’s trying to find the best way for us to play football. He does not have any pet areas. Whatever he can do as a head coach to help the situation. Would he have a right to be ticked off? Absolutely. The tone or whatever was not anything but a conversation about what ways we can improve."

On whether he is concerned about K Alex Henery’s hangtime and distance on kickoffs: "I think, last week in particular, I didn’t do the right thing in training him. He was off a little bit in his steps and he didn’t do as many full length kickoffs as he normally does. He is still delegated the responsibility of going to kick the ball well. He’s not getting the pass on this persay. We did so many field goals last week because we had a new snapper and a new holder, I really wanted his leg to be as spry as it could be for game day. We cut back a little bit on his kickoffs, and it’s like anything else where – if a guy is a free throw shooter, he still practices a lot of free throws – you have to do it over and over. That was a miscalculation on my part."

On whether WR Damaris Johnson will still remain the punt returner: "Yeah, absolutely. I thought he did a great job last week. We had two touchbacks, and usually (a punt returner) doesn’t have any touchbacks. He got one that he caught at the seven, and he could’ve fair caught it, but he got it to the 10. Then, the other one was shanked. I don’t know what else he could have done better than that. I guess he could have gotten the one he brought the one he caught at the seven out for more yardage. Anytime you do this, I know I’ve said you shouldn’t catch it at the eight, but when you catch it at the eight for an eight-yard return, you’ve increased your field position by 100 percent. Those aren’t just cooked up numbers – you start at the eight and you start at the 16. Would I rather it at the 20? I guess that one could be debatable."

On whether P Mat McBriar needed time to adjust and whether that was the reason for almost having a punt blocked: "The reason it almost got blocked was the one of our guys, who is a very good punt protection guy and with the way he plays his position could be better than anyone in the league, really did not do a great job at securing that block. There were a couple of pressures. I think he could get it out faster for sure, but I think the pressure that you saw was more the direct result was not solidly blocking the guy and not using the correct body position when striking than it was on Mat."

On what LB Adrian Moten brings to the special teams unit: "He’s definitely a tough, young scrapper. He looks like one of those guys in Rocky III when Rocky comes in all Dapper Dan and the guys drop their gloves from punching the bag and they’re stripped down, ready to rumble. He’s kind of got that attitude. It’s always good to have a tough, young scrapper on the roster. I think he has that. Our personnel department does a great job there and they are on top of everything. They thought he was the best guy available. They liked him and I liked him, so I think it will parlay into some good plays for us."

On the release of LB Brian Rolle: "You don’t want too much security in this particular profession. At least from my vantage point, too much security hinders your ability to improve. No one should have a whole lot of security. Everybody is judged from week to week, and every decision is made to improve the football team. I think, as an organization, we felt that we had a guy who we released that in hindsight would play better ball than a guy that we kept. I think that was the reason. If coach had another reason other than that, I am unaware of it."

On whether he thinks there is success to be had when icing a kicker: "Icing the kicker is like trick plays or fakes – you’re brilliant if they work and you’re something else if they don’t. That’s all I can say because that’s my experience. Did you think the onsides kick by the Saints was a good move? It was a brilliant move. If it didn’t work, it was a similar situation. That is one of those where a coach is in a tough spot. If the kid had made it as opposed to not making it, everybody’s attitude about icing the kicker would have been different. Before that, you don’t know. Only one person knows that one. You can criticize it, I guess, but I don’t know how you can criticize that one. I think it’s a good call. It’s been used because, again, sometimes it works and sometimes it doesn’t. You don’t know."

On whether he anticipates any personnel changes coming on any of the units: "The thing with starters playing on there, and I’ll repeat this, is that the head coach really has no pet area. He has to win this game and it doesn’t matter how you do it. The best way to win the game is to utilize the talent that you have to the utmost of your ability. I’ll give you an example – we have had (CB) Dominique Rodgers-Cromartie playing on the punt return team and he does a very good job. We replaced him on that unit not because of anything except generally, with the guys he covers, he has to run a bunch of nine routes over and over again.

"When he comes into that play, he’s usually depleted enough that a fresher (CB) Brandon Boykin or (CB) Curtis Marsh could, with the tenacity and vigor and everything, do a better job even though Dominique is a better player. We do have some of those guys playing, and again, that can always be questioned. Whatever makes the football team better is what the head coach does, and I’m all on board with that. 1,000 percent on board. I’ve been trained, and I wasn’t always like this, to look through the eyes of the head coach and the decisions he makes because he has no pet area. He’s doing the right thing, no matter how we come to that decision. That’s our football team, and I think he’s prepped the pie properly."


Q:

Linux memory management and large files

I'm acquiring image objects from a remote server, then attempting to upload them to Rackspace's Cloud Files using their API.  Wondering a) how I can make this process more efficient, and b) assuming I'll need to purchase more memory, what a reasonable amount of RAM might be to accomplish this task (current development server is just 512MB).
In executing the script I'm:

Querying my local database for a set of ids (around 1 thousand)
For each id, querying a remote server, which returns between 10-20 image objects, each image is 25-30k
Create a Cloud Files container, based on the id from my db
For each image object returned from the remote server, create an image object in my container, and write image data to that object
Update row in local db with datetime of added images

This executes relatively quickly on a small set of ids, however 100 (so 700-1k images) can take 5-10min, and anything more than that seems to run indefinitely. Have tried the following, with little success:

using php's set_timeout to kill the script after a couple minutes, figuring that'd purge memory allocated to execution, allowing me to pick up where I left off and work through the set is smaller pieces.  However this error is never thrown
unset the array key containing the image object after it's uploaded (not just the reference inside the loop).

PHP's memory_limit is set to 128MB, and running 'tops' command I see that user 'www-data' was consuming 16% of memory resources. However that no longer appears in the list of users, but I continue to see this:
PID  USER      PR   NI VIRT RES  SHR  S %CPU %MEM  TIME+    COMMAND
2400 mysql     20   0  161m 8220 2808 S    0  1.6  11:12.69 mysqld

...but the TIME+ never changes. I see that there is still 1 task running, yet these values never change:
Mem:    508272k total,   250616k used,   257656k free,     4340k buffers

Apologies for the lengthy post - not entirely sure what (if any of that) is useful.  This is not my area of expertise so grasping at straws a little.  Thanks in advance for your help.

A:

MySQL's a daemon - it'll keep running and sit in memory until it dies or you kill it. The TIME+ is how much cpu time it's used since last restart. If it's idle (%CPU = 0), then TIME+ will not increment, since no cpu time has been consumed.
Have you checked if the cloudfiles API is leaking handles of some sort? You may be unsetting the image object you've retrieved from your service (service->you), but the Cloudfiles API still has to send that image back out the door (you->Rackspace), and that could be leaking somewhere.


1. Field of the Invention
This invention relates to adapting guidance systems to retrofit unguided rockets.
2. Description of the Related Art
Unguided ordnance cannot be steered toward a target and thus exhibit limited lethality. Unguided ordnance also pose considerable collateral damage concerns surrounding their use, particular in urban or “danger close” battlefield situations where friendly forces are in close proximity with enemy combatants. Such ordnance includes artillery and other tube-launched projectiles all of which will be referred to herein as “rockets”.
As shown in FIGS. 1a and 1b, an unguided 2.75″ Hydra-70 rocket 10 is one example of unguided ordnance. The Hydra-70 rocket includes propellant 12 inside a cylindrical airframe 14, a tail assembly 16 that includes a nozzle 18 and fins 20 that deploy to a fixed position upon clearing the launch tube, an explosive warhead 22 and a fuze 24 on the end of the warhead. The fuze includes an external thread form 26 that mates with the warhead's internal thread form 28 to form a threaded interface. Torque is applied to the fuze to drive a fuze lip 30 into the warhead to create an axial load to “preload” the fuze. When launched, the Hydra-70 rocket is spin-stabilized to fly unguided toward a target. Upon impact an initiation charge in fuze 24 transfers energy to the warhead to detonate a primary charge.
Laser, RF, infrared or Global Positioning System/Inertial Navigation System (GPS/INS) guided ordnance is commonly used to engage point targets with a high probability of success and minimal collateral damage. Such ordnance includes guided artillery and other tube-launched projectiles, all of which will be referred to herein as “missiles”. A laser guided missile typically includes a semi-active laser (SAL) seeker to detect laser radiation scattered from the intended target and to provide signals indicative of the target bearing to actuate aero-dynamic surfaces to guide the missile to the target. IR guided missiles sense the infrared radiation emitted from the target to guide the missile. A GPS/INS guided missile uses GPS updates of missile position, heading and velocity to guide the missile to mensurated coordinates programmed into the missile.
Guidance systems can be developed to retrofit unguided rockets to increase the lethality and decrease the collateral damage for the existing design and stores of unguided rockets. However, there are typically no external features present on the rockets to which the guidance systems can be attached in order to accomplish the retrofitting for “guided rockets”.


YEREVAN, MARCH 7, ARMENPRESS. Italy, which chairs the OSCE in 2018, will spare no effort to help and facilitate an agreement between the parties of the NK conflict to reach a sustainable and negotiatied solution, press officer for the Italian OSCE Chairmanship Giovanni Davoli told ARMENPRESS in an exclusive interview.

Italy assumed the OSCE chairmanship starting January, 2018. What will be the priorities of Italy’s chairmanship in the OSCE?

As outlined by Foreign Minister Alfano to the OSCE Permanent Council on 11 January, the priorities for our Chairmanship are as follows: following on from the action of previous Chairmanships, full support for seeking a solution to the crisis in and around Ukraine and the protracted conflicts in the OSCE area. In this context, Minister Alfano carried out a mission to Ukraine (30-31 January 2018), including a visit to the OSCE Special Monitoring Mission in Donbass, and to Moscow (1 February), in his quality as OSCE Chairperson-in-Office; greater attention in the OSCE to the challenges and opportunities arising in the Mediterranean, in particular promoting a more defined role for the OSCE on migration, as underlined at the Mediterranean Conference chaired by Minister Alfano in Palermo on 24 – 25 October 2017; a proactive approach to the OSCE’s three “dimensions” (politico-military, economic-environmental, human rights) and on new transnational threats (terrorism, cybersecurity, combatting illegal trafficking in arms, drugs, cultural goods, and hazardous waste)

As acting Chairman of the OSCE, what prospects do you see for the settlement of the Nagorno Karabakh conflict?

The elements for a solution to the crisis have all already been laid out at the negotiating table, thanks to the focused commitment of the Co-Chairs of the Minsk Group. The validity of the approach so far adopted is therefore fully confirmed: when both parties have been engaged at the top political level, through direct contacts between the two Presidents, we have witnessed positive developments. In this respect, we are in favor and encourage further contacts at the highest level, being aware that the political will of the parties is key in the Nagorno-Karabakh peace process.

Will you have any separate initiative, which might boost the negotiations over the Nagorno Karabakh conflict settlement?

The Italian Chairmanship of the OSCE is committed to pursue a political, negotiated and sustainable solution to the Nagorno-Karabakh conflict. We will act in the vein and consistently with the previous OSCE Chairmanships to support the Co-chairs of the Minsk Group. No effort will be spared on our side to help and facilitate an agreement between the parties, in accordance with the Madrid principles and the Helsinki Final Act.

How would you assess the current level of the Armenian-Italian relations? How do you assess the political dialogue, what are the prospects in terms of boosting economic ties?

Our bilateral relations with Armenia are excellent and based on solid historic and cultural ties. We consider Armenia a close friend and a reliable partner in the region, both at the political and economic level. The intensity of our relations is proved by many important initiatives organized throughout 2017, such as the first session of the Joint Economic Commission, held in Rome last June. As far as the economic ties are concerned, there are many complementarities between our economies. At the same time, we believe there are broad margins to further increase our cooperation, especially in the industrial sector and bilateral trade. We will therefore work to strengthen these ties both at the institutional and promotional level, to the benefit of our civil societies and enterprises.

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Those, who have committed copyright violations, will be prosecuted accordingly.Website administration is not responsible neither for opinions expressed on the website, nor for the content of the advertisements and of the external links.


I'm Jackie and I watch TV. I'm not proud. Reviews, some recaps, TV news, reality television, primetime and even a weekly off television topic photo post. Bookmark the blog now as your source for live feed reports from inside the 'Big Brother' house! Come, join in on the fun ...

Saturday, September 03, 2016

BB18: Live Feeds into Saturday Morning - September 3

Cap'n Crunch from the box

Here's the latest from inside that Big Brother House of Pain:

Yes, pain.

Pain because all involved in the HoH comp have sore hands and little cuts on their fingers.

Pain because I'm watching them do nothing but cook, eat, and play dominoes.

Pain because Natalie keeps fussing that she will miss James, can't win comps and no one talks to her (other than James).

Pain because James keeps showing compassion to Natalie, the person he let lose him the game all summer.

Other than James coaching Natalie what to do after he goes, there's no strategy talk.

This is what boredom on video is, BB18 when there's no hope for excitement to come.

If James or Natalie win veto and one gets taken off the block, there's no expectation that there will be a blindside and someone other than the remaining one will go home.

28 comments:

After this next eviction (no doubt, James), I think Paul will start working on getting Victor out. I'm pretty sure that will be a shock to Victor... having his guaranteed F2 BFF turn on him.

If he's going to get out Victor, his best chance is getting the next HOH and blindsiding Victor. Paul could be "counting his chickens" if he thinks he can beat Nicole and Natalie in any upcoming comps (Corey is a given, lol).

Just get Corey out. He's a waste of time. I don't like the way they are treating Natalie. I know what it is for people not talk to you. Their day is coming. Sooner than they think. I know James is going out and I hate that. We'll see.

Depressing & boring, Jackie. Not your fault, I know. I feel for you. I need todonate EXTRA this week for your alcohol fund! LOL Just to be able to watch thisdrivel, you must have to be at least a little lit *wink*

As far as Paul and Victor are concerned, I'm sure Corey's ONLY worth is his vote. Corey assumes he's completely safe now that he and Nicole have a F4 agreement. Heck, Corey probably thinks the old "F3 Bro-Alliance" is still in effect.

Corey is much more important than Nicole ya'know, so he's not even inclined to study for upcoming mental comps. In fact, his whole demeanor has been announcing how completely bored he is with the whole BB experience. Almost as bored as we are with him.

Getting Corey out is not strategic. He's not a threat in competitions, nor for jury votes. Threats, in order of ability to win both comps and jury votes, are Victor/Paul, James, the other half of Victor/Paul, Nicole, Natalie, and then Cory.

Silk, agree completely. At this point, Corey will be the last one considered for eviction because he hasn't won anything that hasn't been handed to him.

So this is highly unlikely, but the thought kind of has me both appalled and snickering...Wouldn't it be funny if Corey somehow makes it to F3, with the other 2 a mix of 1 male/1 female? Then somehow Corey manages to become the final HOH who choose the HG going with him to F2? Now THAT would be an Season 18 abomination!!

Corey winning the final part of the final HOH would be the ultimate shocker and long-shot of the season. It won't happen. He didn't have any conversations with any of the jurors other than Paulie. He's been holed up in bed with Nicole the entire season.

I don't like the lack of talking either Jackie H. It does bother me. But, in all fairness, neither Natalie nor Nicole have spent any bonding time together! Natalie spent most of her time tied to others (3 girls B, M, then Bridget) and James. Nicole spent most of her time with C, Z, P, and Paulie.

Two of the remaining three Showmances have spent this season mainly by themselves, so they don't even know what they may have in common or what to talk about besides game talk... and that was even limited between Nic, C, J and Nat.

Neither one of the two girls have reached out to each other, nor have they really trusted each other... Which I feel made it difficult for Nicole to truly trust that James wouldn't side with Michelle and Natalie and turn on C and Nic. Especially with James telling Victor (in front of everyone) that Natalie wanted to vote out Corey rather than Victor AND that they even fought over it! That was a little stupid. That was when Corey and Nicole first started questioning should they trust their foursome... BEFORE they agreed to team up with Victor and Paul (just rewatched that).

Nicole was already goosy when it came to Michelle, but that slip of the tongue and the lack of communication between M, J, Nat, C, and Nic just opened the door wide for V and P to slip in! Victor and Paul have worked very hard to keep the others from having any bonding time or fun together!

I hope James wins POV. I would love to see Corey put on the block and sent home... But I think they would vote out Nat before C. Frustrating...

Thanks Monty, I forgot all 6 will play. Of course, that leaves even less chance for James to win, especially if it's something like the Comic or Morph comp.

James readily admits he's not good at those comps, but in both seasons, he hasn't spent any time studying for those. When your BB life is on the line, I don't understand that kind of thought process... or lack of it?

Silk, I agree that Corey isn't a threat to win the game and would be a great goat (hate even having to type that last word considering) to take to the end, but that in and of itself is the perfect reason to get rid of him. Why would anyone want to let a Victoria go to the final 3 again if they themselves have a shot at final 3? You have to get there to have a chance at final 2. I would never leave the "goat" in there myself.


Q:

Converting seq to string[] in F#

The example from this post has an example
open System.IO

let lines =
  File.ReadAllLines("tclscript.do")
  |> Seq.map (fun line ->
      let newLine = line.Replace("{", "{{").Replace("}", "}}")
      newLine )

File.WriteAllLines("tclscript.txt", lines)

that gives an error when compilation.
error FS0001: This expression was expected to have type
    string []
but here has type
    seq<string>

How to convert seq to string[] to remove this error message?

A:

Building on Jaime's answer, since ReadAllLines() returns an array, just use Array.map instead of Seq.map
open System.IO

let lines =
  File.ReadAllLines("tclscript.do")
  |> Array.map (fun line ->
      let newLine = line.Replace("{", "{{").Replace("}", "}}")
      newLine )

File.WriteAllLines("tclscript.txt", lines)

A:

You can use
File.WriteAllLines("tclscript.txt", Seq.toArray lines)

or alternatively just attach
|> Seq.toArray

after the Seq.map call.
(Also note that in .NET 4, there is an overload of WriteAllLines that does take a Seq)


Stanley, Perthshire

Stanley is a village on the north side of the River Tay in Perthshire, Scotland, around  north of Perth.

The section of the River Tay near the village is a popular location for canoeing and fishing.

Etymology
The village of Stanley gains its name from Lady Amelia Stanley, the daughter of James Stanley, 7th Earl of Derby. In the 1600s the area around Stanley was part of the estate of Earls of Atholl and was also the location of Inchbervis Castle. In 1659 the castle was renamed Stanley House in honour of  the wedding of John Murray, 1st Marquess of Atholl and Lady Stanley. When the village was built in the 1700s it took the name Stanley after the nearby house.

History
John Murray, the 4th Duke of Atholl, decided in the 18th century to harness of the nearby River Tay to power a cotton mill. Richard Arkwright, an inventor of cotton-spinning machinery was persuaded by George Dempster (the local MP), while Dempster was visiting Cromford in Derbyshire, to come to Scotland to set up a cotton mill in Stanley as well as one at New Lanark. Stanley Mills opened in 1787, and by its 10th year employed 350 people.

The village of Stanley was built to house the workers of the mill. Work on the village began in 1784. It was designed by the Duke of Atholl’s factor James Stobie. By 1799 the village’s population was around 400, and by 1831 it had reached around 2,000 residents, about 50% of whom worked in the mill.

Stanley Mill
Stanley was largely founded to house workers for a huge mill on the banks of the River Tay.

The mill was originally water-powered but was later converted to steam and finally to electric power. For most of its history it produced cotton thread, but in the 20th century changed to cigarette ribbon.  The Dempster & Co company was established in 1787 by seven men including Richard Arkwright, George Dempster and William Sandeman to build the mill on land feued from the Duke of Atholl to provide employment to Highlanders affected by the clearances. A fire in 1799 destroyed a large section of the mill and it reopened in 1802, partly with advice from David Dale of New Lanark (which it closely resembles).

The mill used coal gas for lighting until 1921, when this was replaced by a hydroelectric power plant, which was built to also supply electricity to the village.  The power station was closed in 1965 but was reopened in 2003 by npower (UK).

From the 1960s the mill was in decline, and it finally closed down in 1989. After that the mill fell derelict. Historic Scotland bought the mill in 1995 and over the next ten years, in liaison with the Phoenix Trust, the buildings renovated and turned into private flats plus a museum depicting life in the 19th century and the story of the mill.

Railway
A railway station was built in Stanley in 1848. This later evolved into a junction station, as it lay at the point where the branch line to Forfar broke off from the Highland Main Line. The Highland Main Line still runs though the village, but the station was closed in 1956.

Ballathie House
Ballathie House was built during the 1850s near Stanley. It was built by the Robertson family, the land having originally been owned by the Drummond family, the Earls of Perth. Since 1972 it has operated as a country house hotel.

References

External links

  Jim Donaldson's Unofficial Stanley Website
 Princes Regeneration Stanley Mills Information
 A visit to Stanley Mills

Category:Villages in Perth and Kinross


The Huffington Post Australia spoke to Dr Katherine Johnson, a senior psychology lecturer at the University of Melbourne, to breakdown some myths about our attention spans and consequently, how we can help increase them.

Dr Johnson is studying attention control in children and adults over time, so there's probably no one in the country better to explain how to avoid reaching for our phones five minutes into a movie.

What is the exact definition of our attention span?

There are two different terms (and meanings) behind our attention spans in psychology.

Visual attention span: "It's literally how many things can you pay attention to on a screen in a particular amount of time," Johnson said.

Sustained attention span: "Which is concentrating on a task for a long period of time without getting distracted by anything else, and it's particularly difficult if the task is boring."

"Technology is just another example of a distraction. Ultimately it's under our control, so if we can recognise that we're allowing ourselves to be distracted, we can also convert it into a reward," Johnson said.

Also, contrary to belief, you cannot do two tasks at once. Johnson said when we think we're doing two things at once, like walking and texting, or watching a movie and trawling instagram, we're actually just quickly microswitching between tasks.

"It leads to a worse performance on both tasks, compared to just doing one task at a time."

What else can we do to improve our attention spans?

1. Find a quiet space

There is a network in the brain that is "aroused" when it's alerted to random noises, said Johnson, so finding a quiet space without distractions is best to clear your inbox.

Which is bad news for workers in open plan offices. However, regular noise is fine as the specific brain network adapts. If the open plan office is quiet, you'll have no problems, but if there's irregular noise, listening to music quietly may even help eradicate the loud outbursts of chatter.

"It's that irregular noise that will capture your attention and drag you away from your task," Johnson said.

"So if you have better aerobic fitness you are more likely to perform better. So there's another reason to go for a run."

So there is science behind exercising in the morning (and no, the below doesn't count)

Paul Bradbury

3. Buy a pot plant

Research conducted by Johnson and her colleagues at The University of Melbourne revealed when people are exposed to greenery performed long tasks better.

"It also helps people's cooperation in the workplace," Johnson said.

They don't yet know whether it's exposure to nature or the colour green that does wonderful things, but having a pot plant with greenery in your office or on your desk certainly helps. Or a photo of greenery in sight.

4. Drink green tea

"In green tea there's a little bit of caffeine but also an element called Theanine, and they improve sustained attention performance," Johnson said.

Dimitri Otis

5. Meditate

You can improve your attention control if you can meditate, said Johnson.

"It makes sense, because when you're meditating you're concentrating on either one thing or a blankness, so you're exercising that muscle in the brain."

That 'muscle' is a network in the brain which controls sustained attention (involving parts of the frontal cortex and parts of the parietal cortex in the back of the brain).


After the state originally announced that it would dump the tailings directly into the Berkeley Pit, and then decided to put the waste dirt on a ramp to the pit instead. Then, an alternate plan was announced in which the tailings would be dumped on Montana Resources property. Under that plan, MR would have moved the tailings to a leach pad eventually and processed them to remove the recoverable metals.

Last month, it was announced that the state and Montana Resources could not come to agreement on the specifics of the leaching plan, including indemnifying each other for potential legal liability. Then the state said it would go back to the Berkeley pit ramp plan. But that, too, required an agreement. Montana Resources has indicated it is willing to provide an access agreement to the state — but due to its contractual obligations, MR needs a sign-off from ARCO to grant that agreement. ARCO has refused to go along.

“In our view,” the ARCO spokesman said, “Placing the excavated material on the active mine site where it could be reprocessed, would be a safer and lower-cost solution than disposal on the ramp in the Berkeley Pit. Atlantic Richfield would strongly support reprocessing in the active mine site."

Harris said the state "is in contact with ARCO at just about every level" and expects to keep working toward an agreement.