Case Report {#sec1}
===========

A 59-year-old man with medical history significant for vasculopathy and alcohol abuse presents with elevated lipases and diagnosed with pancreatitis. Because of pain out of proportion on physical examination, the patient was suspected of having mesenteric ischemia. Doppler imaging of the mesenteric vessels was ordered, and subsequently revealed multiple thrombi in the superior mesenteric vein, portal vein, and the splenic vein ([Fig. 1](#fig1){ref-type="fig"}). On hospital day 2, the patient experienced a drop in hemoglobin/hematocrit of 11.7 g dL^−1^/34.2-7.07 g dL^−1^/20.0 with associated decline of blood pressure to 85/45 mm Hg. The patient was transfused 3 units of packed red blood cells. Abdominal computed tomography (CT) demonstrated a large splenic subcapsular hematoma with a moderate amount of hemoperitoneum and active site of extravasation from the spleen ([Fig. 2](#fig2){ref-type="fig"}). In addition, a pseudoaneursym arising from the distal splenic artery was discovered, and the extent of portal and splenic venous thrombosis was appreciated ([Figs. 3](#fig3){ref-type="fig"} and [4](#fig4){ref-type="fig"}). Because of the patient's hemodynamic instability and comorbidities, the patient was an unfit candidate for general anesthesia and general surgery. Interventional radiology was consulted for splenic artery embolization.

Although no active contrast extravasation from the splenic artery was identified, splenic arteriography did discover a 6 to 7-mm pseudoaneurysm near the distal aspect of the splenic artery ([Fig. 5](#fig5){ref-type="fig"}). The catheter was positioned proximal to the pseudoaneurysm, and subsequently, a 7-mm Amplatzer vascular plug was deployed to staunch blood flow into the pseudoaneurysm. A 15-minute delayed angiography demonstrated very scant contrast opacification distal to the plug. Vascular flow was maintained proximal to the Amplatzer plug to ensure continued perfusion to the distal pancreatic territory ([Fig. 6](#fig6){ref-type="fig"}). On postprocedure day 1, the patient's hemoglobin and/or hematocrit returned to near baseline of 10.5 g dL^−1^/35.0 and blood pressure to 110/70 mm Hg. The patient maintained stable hemodynamics 1 week after embolization at which time a splenectomy was performed. The patient tolerated the splenectomy well and was subsequently discharged on postoperative day 14.

Discussion {#sec2}
==========

Atraumatic splenic rupture is a rare phenomenon, with estimates of its incidence between 0.1% and 0.5% [@bib1]. In the medical literature, atraumatic splenic rupture can refer to 2 possible cases, the first being a spontaneous rupture of a normal spleen, more appropriately termed as a spontaneous rupture, and the second being a spontaneous rupture of a diseased spleen, termed a pathologic rupture [@bib2]. A true spontaneous rupture is thought to be much less common [@bib3]. Atraumatic splenic rupture of a pathologic spleen is more extensively documented, and the rupture of the spleen is thought to manifest because of underlying diseases [@bib4].

Findings from a systematic review of atraumatic splenic rupture indicate that a vast majority of atraumatic splenic rupture patients have 1 etiologic factor that precipitates atraumatic splenic rupture. An abridged table from Renzulli et al listing common etiologies is provided in [Table 1](#tbl1){ref-type="table"}. The systematic review noted that approximately 7% of patients had no etiologic factor for atraumatic splenic rupture [@bib5]. Splenomegaly was seen in more than half (55%) of atraumatic splenic rupture patients, whereas a normal sized spleen was observed in approximately 15% of patients [@bib5]. This could lend credence to the possibility of splenomegaly being a common feature of atraumatic splenic rupture. Approximately 84% of atraumatic splenic rupture patients received treatment in the form of total splenectomy. Although transcatheter arterial embolization can be used in unstable patients, less than 1% of patients received this form of treatment. The study also found both an age greater than 40 years and splenomegaly to be significant factors for predicting atraumatic splenic rupture-related mortality [@bib5].

The most common reported cause of atraumatic splenic rupture is malignant hematologic disorders, followed by infectious and inflammatory disorders [@bib3], [@bib5]. Although unclear, potential pathophysiologic mechanisms for atraumatic splenic rupture have been hypothesized, such as distention of the spleen because of infiltration of splenic parenchyma and hemorrhage of the splenic capsule due to infarct [@bib6]. Infiltration of splenic parenchyma is thought to be a possible mechanism for malignant hematologic disorders [@bib6], [@bib7].

As presented in this case, pancreatitis is also thought to be a common cause of atraumatic splenic rupture [@bib3], [@bib5] because of the sequela of splenic vein thrombosis [@bib7]. Rupture of the spleen from splenic venous thrombosis revolves around gradual accumulation of pressure and congestion within the splenic parenchyma due to venous outflow obstruction. Increased intracapsular pressure will drop arterial perfusion pressure thereby causing the spleen to undergo necrotic dehiscence.

Aside from pancreatitis, there have been reported cases of splenic vein thromboses due to cardiac surgery, septic emboli from infective endocarditis, and atherosclerosis from chronic renal failure [@bib8], [@bib9], [@bib10], [@bib11]. There also has been a reported incidence of toxic megacolon from underlying ulcerative colitis, which can cause splenic venous thrombosis and lead to splenic rupture [@bib12]. Thrombophilia in patients afflicted with paroxysmal nocturnal hemoglobinuria has been documented to have caused splenic rupture through splenic venous thrombosis [@bib13]. Heparin-induced thrombocytopenia has also been implicated in development of splenic venous thrombosis that ultimately lead to splenic rupture [@bib14], [@bib15]. Furthermore, acquired amyloidosis due to injectable drugs and protein S deficiency were also observed as causes of atraumatic splenic rupture [@bib16], [@bib17].

It has been reported that a diagnosis of a ruptured spleen is frequently not considered in the absence of trauma, even in the presence of pain in the upper left quadrant and hemodynamic instability, which can lead to devastating outcomes [@bib18]. In these instances, the use of diagnostic tools may greatly increase an accurate diagnosis of atraumatic splenic rupture. The systematic review found that for a diagnosis of free-intraperitoneal fluid, ultrasonography was used in 24.6% of patients and CT was used in 23% of patients [@bib5]. Diagnosis of atraumatic splenic rupture was made by ultrasonography in 18.6% of patients and by CT in 32.4% of patients [@bib5]. Use of CT is the preeminent technique for diagnosis [@bib19], since CT can provide for a conclusive diagnosis of atraumatic splenic rupture [@bib20]. The use of ultrasound is also supported, with the literature purporting a sensitivity of 72%-78% and a specificity of 91%-100% for the diagnosis of atraumatic splenic rupture [@bib6], [@bib20], [@bib21].

The 2 most common forms of atraumatic splenic rupture treatment are total splenectomy and conservative treatment [@bib5]. Management via conservative and nonoperative means have low rates of success, and will ultimately later necessitate a splenectomy due to rebleeding [@bib6]. The atraumatic splenic rupture-related mortality rate tends to increase significantly if patients have to undergo secondary surgery after conservative treatment [@bib5]. The definitive treatment of atraumatic splenic rupture is splenectomy. From the systematic review by Renzulli et al [@bib5], there was a 7.4% atraumatic splenic rupture-related mortality rate in patients receiving a total splenectomy. Nonetheless, there are lifelong risks associated with the total splenectomy procedure, such as increased risk for sepsis and infections, and an increased risk for thromboembolic complications, arteriosclerosis, and coronary heart disease [@bib22]. When considering therapeutic options, assessment of hemodynamic stability, whether the patient is fit for general anesthesia, the amount of blood products used, degree of hemoperitoneum, and magnitude of splenic injury are paramount in guiding treatment [@bib5]. In the setting of atraumatic splenic rupture precipitated by splenic vein thrombosis, there has been documented utilization of conservative management and eventual regression of a chronic-appearing subcapsular splenic hematoma in an otherwise hemodynamically stable patient [@bib19].

This study has been exempted from IRB approval.

Competing Interests: The authors have declared that no competing interests exist.

![Ultrasound of the splenic vein demonstrates acute nonocclusive thrombus (arrow).](gr1){#fig1}

![Contrast-enhanced computed tomography abdomen demonstrates a small area of contrast extravasation (arrow) in an enlarged, heterogeneous spleen with multiple areas of parenchymal devascularization. Hemoperitoneum was also evident.](gr2){#fig2}

![Contrast-enhanced axial computed tomography abdomen pelvis shows thrombus formation at the portal confluence with extension into the splenic vein (arrow).](gr3){#fig3}

![Coronal maximum intensity projection shows pseudoaneursym at the distal splenic artery (arrow).](gr4){#fig4}

![A 6 to 7-mm pseudoaneurysm is seen at the distal splenic artery. No indication of active extravasation in the splenic parenchyma. Several subtle areas of nodular luminal irregularity could represent distal third and fourth order splenic artery pseudoaneurysms.](gr5){#fig5}

![The distal construct of the Amplatzer plug shows very minimal contrast opacification with significantly reduced flow seen in the splenic arterial bed distally. There is preserved perfusion of the distal pancreatic bed territory.](gr6){#fig6}

######

Common etiologies for atraumatic splenic rupture.

  Etiologies for atraumatic splenic rupture     Number of factors (%)[∗](#tbl1fnlowast){ref-type="table-fn"}
  --------------------------------------------- --------------------------------------------------------------
  Malignant hematologic disorders               152 (16.4)
   Acute myelogenous leukemia                   21 (2.3)
   Non-Hodgkin's lymphoma                       55 (5.9)
  Viral infectious disorders                    137 (14.8)
   Infectious mononucleosis                     102 (11.0)
   Cytomegalovirus infection                    13 (1.4)
  Local inflammatory and neoplastic disorders   101 (10.9)
   Chronic pancreatitis                         65 (7.0)
   Acute pancreatitis                           20 (2.2)
  Primary neoplastic disorders                  75 (8.1)
   Angiosarcoma                                 31 (3.3)
   Peliosis                                     18 (1.9)
  Normal spleen                                 59 (6.4)
   Normal spleen without triggering factor      41 (4.4)
   Normal spleen with triggering factor         18 (1.9)

A total of 926 etiologic factors were present in the 845 patients. A total of 711 patients had only one etiologic factor. Percentages are approximated and are calculated based on a total of 926 factors.


1. Field of the Invention
This invention relates to a novel and improved fluid tight sensor case and specifically to a fluid tight geophone case for use with a cable attached to a geophone wherein the cable is clamped within the case and is electrically connected to terminals on a geophone and the entire assembly of cable, geophone and case is fluid tight.
This invention has utility in the geophysical industry. Electrical cables with sensors, such as geophones, electrically connected thereto are used in seismic acquisition systems for generating and recording seismic data. The use of geophones in a wet or humid environment is required. Such environments include surface water, puddles, swamps, marsh lands or the like. The use of the fluid tight geophone case with an electrical cable and geophone results in a fluid tight assembly which prevents fluid from entering into the cable orifice, the case nose, and case top and into disruptive contact with the interior of the geophone case.
2. Disclosure of the Prior Art
It is known in the prior art to utilize fluid tight cases for electrical cable and geophone assemblies. One known prior art device is a Fluid-Tight Enclosure for Geophone and Cable disclosed in U.S. Pat. No. 3,993,859, wherein a flexible header, stress ring and housing form a fluid tight seal around a cable which passes through the flexible header and is electrically connected to the geophone. Other known prior art devices utilize threaded plastic members having O-ring seals and sealing means surrounding the cable which passes therethrough to form a fluid tight seal.


No More Breast Cancer campaign is based on the report Breast Cancer: an environmental disease. The case for primary prevention. We thank the following organisations for their funding and support of the report

Primary prevention is the answer

Breast cancer: Europe

Information on this webpage is drawn from our 2005 report: Breast Cancer
- an Environmental Disease: The Case for Primary Prevention, available free
as a pdf, see Downloads. For current statistics
and data, see our homepage.

This graph shows the estimated incidence and mortality rates per 100,000 of the population using age-standardised rates (ASRs). ASR allows the comparison of rates in populations that have different age structures and over different periods of time.

Breast Cancer in Europe 2006

Within the European Union, every 2.5 minutes a woman is diagnosed with breast cancer. Every 7.5 minutes a woman dies from the disease.Stella Kyriakides, President of Europa Donna, the European Breast Cancer Coalition. Sue Claridge, in 'The Beacon' (Breast Cancer Network Australia's magazine) Issue 29, Summer 2004 p10

We have strong scientific evidence about toxic chemicals in the environment that mimic female sex hormones and overload a woman's hormonal system, a known cause of breast cancer. We know how pesticides, industrial pollutants, radiation and other factors are linked - part of the social context of breast cancer. Yet, neither government agencies nor societies responsible for dealing with breast cancer acknowledge this context. WHY?
Professor Ross Hume Hall 'Female Biology, Toxic Chemicals and Preventing Breast Cancer: A Path Not Taken' International Conference on Breast Cancer and the Environment Ontario Canada November 1995


Blau’s Saukville Meats is a full-service butcher shop where you can buy ready-to-grill Wisconsin style brats (bratwurst), freshly made from beef, pork, pork and mustard, buffalo and – perhaps the most delicious of them all – chicken, which drips with juices when severed by a knife. The meat cases are also stocked with firm-fleshed summer sausage, smoked meats, and a wide variety of hand-cut beefsteaks, plus hamburger and stewing meat of all kind.

66% Approval Rating (3 votes)

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FreeBSD Man Pages

MAKE.CONF(5) FreeBSD File Formats Manual MAKE.CONF(5)
NAMEmake.conf -- system build information
DESCRIPTION
The file make.conf contains system-wide settings that will apply to every
build using make(1) and the standard sys.mk file. This is achieved as
follows: make(1) processes the system makefile sys.mk before any other
file by default, and sys.mk includes make.conf.
The file make.conf uses the standard makefile syntax. However, make.conf
should not specify any dependencies to make(1). Instead, make.conf is to
set make(1) variables that control the actions of other makefiles.
The default location of make.conf is /etc/make.conf, though an alterna-
tive location can be specified in the make(1) variable __MAKE_CONF. You
may need to override the location of make.conf if the system-wide set-
tings are not suitable for a particular build. For instance, setting
__MAKE_CONF to /dev/null effectively resets all build controls to their
defaults.
The primary purpose of make.conf is to control the compilation of the
FreeBSD sources, documentation, and ported applications, which are usu-
ally found in /usr/src, /usr/doc, and /usr/ports. As a rule, the system
administrator creates make.conf when the values of certain control vari-
ables need to be changed from their defaults.
The system build procedures occur in four broad areas: the world, the
kernel, documentation and ports. Variables set in make.conf may be
applicable in one, two, or all four of these areas. In addition, control
variables can be specified for a particular build via the -D option of
make(1) or in environ(7).
The following lists provide a name and short description for each vari-
able you can use during the indicated builds. The values of variables
flagged as bool are ignored; the variable being set at all (even to
``FALSE'' or ``NO'') causes it to be treated as if it were set.
The following list provides a name and short description for variables
that are used for all builds, or are used by the makefiles for things
other than builds.
ALWAYS_CHECK_MAKE
(bool) Instructs the top-level makefile in the source tree
(normally /usr/src) to always check if make(1) is up-to-
date. Normally this is only done for the world and build-
world targets to handle upgrades from older versions of
FreeBSD.
CFLAGS (str) Controls the compiler setting when compiling C code.
Optimization levels other than -O and -O2 are not sup-
ported. BDECFLAGS is provided as a set of cc(1) settings
suggested by Bruce Evans <bde@FreeBSD.org> for developing
and testing changes. They can be used, if set, by:
CFLAGS+=${BDECFLAGS}
CPUTYPE (str) Controls which processor should be targeted for gen-
erated code. This controls processor-specific optimiza-
tions in certain code (currently only OpenSSL) as well as
modifying the value of CFLAGS and COPTFLAGS to contain the
appropriate optimization directive to cc(1). The automatic
setting of CFLAGS and COPTFLAGS may be overridden using the
NO_CPU_CFLAGS and NO_CPU_COPTFLAGS variables, respectively.
Refer to /usr/share/examples/etc/make.conf for a list of
recognized CPUTYPE options.
CXXFLAGS (str) Controls the compiler settings when compiling C++
code. CXXFLAGS is initially set to the value of CFLAGS.
If you want to add to the CXXFLAGS value, use ``+=''
instead of ``=''.
INSTALL (str) the default install command. To install only files
for which the target differs or does not exist, use
INSTALL+= -C
Note that some makefiles (including those in /usr/share/mk)
may hardcode options for the supplied install command.
LOCAL_DIRS (str) List any directories that should be entered when
doing make's in /usr/src in this variable.
MAKE_SHELL (str) Controls the shell used internally by make(1) to
process the command scripts in makefiles. sh(1), ksh(1),
and csh(1) all currently supported.
MAKE_SHELL?=sh
MTREE_FOLLOWS_SYMLINKS
(str) Set this to ``-L'' to cause mtree(8) to follow sym-
links.
NO_CPU_CFLAGS
(str) Setting this variable will prevent CPU specific com-
piler flags from being automatically added to CFLAGS during
compile time.
NO_CPU_COPTFLAGS
(str) Setting this variable will prevent CPU specific com-
piler flags from being automatically added to COPTFLAGS
during compile time.
NO_DOCUPDATE (bool) Set this to not update the doc tree during ``make
update''.
NO_PORTSUPDATE
(bool) Set this to not update the ports tree during ``make
update''.
SVN_UPDATE (bool) Set this to use svn(1) to update your src tree with
``make update''. Note that since a subversion client is
not included in the base system, you will need to set SVN
to the full path of a svn(1) binary.
BUILDINGTHEKERNEL
The following list provides a name and short description for variables
that are only used doing a kernel build:
BOOTWAIT (int) Controls the amount of time the kernel waits for a
console keypress before booting the default kernel. The
value is approximately milliseconds. Keypresses are
accepted by the BIOS before booting from disk, making it
possible to give custom boot parameters even when this is
set to 0.
COPTFLAGS (str) Controls the compiler settings when building the ker-
nel. Optimization levels above [-O (-O2, ...)] are not
guaranteed to work.
KERNCONF (str) Controls which kernel configurations will be built by
``${MAKE} buildkernel'' and installed by ``${MAKE}
installkernel''. For example,
KERNCONF=MINE DEBUG GENERIC OTHERMACHINE
will build the kernels specified by the config files MINE,
DEBUG, GENERIC, and OTHERMACHINE, and install the kernel
specified by the config file MINE. It defaults to GENERIC.
MODULES_OVERRIDE
(str) Set to a list of modules to build instead of all of
them.
NO_KERNELCLEAN
(bool) Set this to skip running ``${MAKE} clean'' during
``${MAKE} buildkernel''.
NO_KERNELCONFIG
(bool) Set this to skip running config(8) during ``${MAKE}
buildkernel''.
NO_KERNELDEPEND
(bool) Set this to skip running ``${MAKE} depend'' during
``${MAKE} buildkernel''.
NO_KERNELOBJ (bool) Set this to skip running ``${MAKE} obj'' during
``${MAKE} buildkernel''.
NO_MODULES (bool) Set to not build modules with the kernel.
PORTS_MODULES
Set this to the list of ports you wish to rebuild every
time the kernel is built.
WITHOUT_MODULES
(str) Set to a list of modules to exclude from the build.
This provides a somewhat easier way to exclude modules you
are certain you will never need than specifying
MODULES_OVERRIDE. This is applied afterMODULES_OVERRIDE.
BUILDINGTHEWORLD
The following list provides a name and short description for variables
that are used during the world build:
BOOT_COMCONSOLE_PORT
(str) The port address to use for the console if the boot
blocks have been configured to use a serial console instead
of the keyboard/video card.
BOOT_COMCONSOLE_SPEED
(int) The baud rate to use for the console if the boot
blocks have been configured to use a serial console instead
of the keyboard/video card.
BOOT_PXELDR_ALWAYS_SERIAL
(bool) Compile in the code into pxeboot(8) that forces the
use of a serial console. This is analogous to the -h
option in boot(8) blocks.
BOOT_PXELDR_PROBE_KEYBOARD
(bool) Compile in the code into pxeboot(8) that probes the
keyboard. If no keyboard is found, boot with the dual con-
sole configuration. This is analogous to the -D option in
boot(8) blocks.
ENABLE_SUID_K5SU
(bool) Set this if you wish to use the ksu utility. Other-
wise, it will be installed without the set-user-ID bit set.
ENABLE_SUID_NEWGRP
(bool) Set this to install newgrp(1) with the set-user-ID
bit set. Otherwise, newgrp(1) will not be able to change
users' groups.
LOADER_TFTP_SUPPORT
(bool) By default the pxeboot(8) loader retrieves the ker-
nel via NFS. Defining this and recompiling
/usr/src/sys/boot will cause it to retrieve the kernel via
TFTP. This allows pxeboot(8) to load a custom BOOTP disk-
less kernel yet still mount the server's / rather than load
the server's kernel.
LOADER_FIREWIRE_SUPPORT
(bool) Defining this and recompiling /usr/src/sys/boot/i386
will add dcons(4) console driver to loader(8) and allow
access over FireWire(IEEE1394) using dconschat(8). Cur-
rently, only i386 and amd64 are supported.
MALLOC_PRODUCTION
(bool) Set this to disable assertions and statistics gath-
ering in malloc(3). It also defaults the A and J runtime
options to off. Disabled by default on -CURRENT.
MODULES_WITH_WORLD
(bool) Set to build modules with the system instead of the
kernel.
NO_CLEAN (bool) Set this to disable cleaning during ``make
buildworld''. This should not be set unless you know what
you are doing.
NO_CLEANDIR (bool) Set this to run ``${MAKE} clean'' instead of
``${MAKE} cleandir''.
NO_MANCOMPRESS
(bool) Set to install manual pages uncompressed.
NO_SHARE (bool) Set to not build in the share subdir.
NO_SHARED (bool) Set to build /bin and /sbin statically linked, this
can be bad. If set, every utility that uses bsd.prog.mk
will be linked statically.
PPP_NO_NAT (bool) Build ppp(8) without support for network address
translation (NAT).
PPP_NO_NETGRAPH
(bool) Set to build ppp(8) without support for Netgraph.
PPP_NO_RADIUS
(bool) Set to build ppp(8) without support for RADIUS.
PPP_NO_SUID (bool) Set to disable the installation of ppp(8) as a set-
user-ID root program.
SENDMAIL_ADDITIONAL_MC
(str) Additional .mc files which should be built into .cf
files at build time. The value should include the full
path to the .mc file(s), e.g., /etc/mail/foo.mc,
/etc/mail/bar.mc.
SENDMAIL_ALIASES
(str) List of aliases(5) files to rebuild when using
/etc/mail/Makefile. The default value is
/etc/mail/aliases.
SENDMAIL_CFLAGS
(str) Flags to pass to the compile command when building
sendmail(8). The SENDMAIL_* flags can be used to provide
SASL support with setting such as:
SENDMAIL_CFLAGS=-I/usr/local/include -DSASL
SENDMAIL_LDFLAGS=-L/usr/local/lib
SENDMAIL_LDADD=-lsasl
SENDMAIL_CF_DIR
(str) Override the default location for the m4(1) configu-
ration files used to build a .cf file from a .mc file.
SENDMAIL_DPADD
(str) Extra dependencies to add when building sendmail(8).
SENDMAIL_LDADD
(str) Flags to add to the end of the ld(1) command when
building sendmail(8).
SENDMAIL_LDFLAGS
(str) Flags to pass to the ld(1) command when building
sendmail(8).
SENDMAIL_M4_FLAGS
(str) Flags passed to m4(1) when building a .cf file from a
.mc file.
SENDMAIL_MAP_PERMS
(str) Mode to use when generating alias and map database
files using /etc/mail/Makefile. The default value is 0640.
SENDMAIL_MAP_SRC
(str) Additional maps to rebuild when using
/etc/mail/Makefile. The access, bitdomain, domaintable,
genericstable, mailertable, uucpdomain, and virtusertable
maps are always rebuilt if they exist.
SENDMAIL_MAP_TYPE
(str) Database map type to use when generating map database
files using /etc/mail/Makefile. The default value is hash.
The alternative is btree.
SENDMAIL_MC (str) The default m4(1) configuration file to use at
install time. The value should include the full path to
the .mc file, e.g., /etc/mail/myconfig.mc. Use with cau-
tion as a make install will overwrite any existing
/etc/mail/sendmail.cf. Note that SENDMAIL_CF is now depre-
cated.
SENDMAIL_SET_USER_ID
(bool) If set, install sendmail(8) as a set-user-ID root
binary instead of a set-group-ID binary and do not install
/etc/mail/submit.{cf,mc}. Use of this flag is not recom-
mended and the alternative advice in /etc/mail/README
should be followed instead if at all possible.
SENDMAIL_START_SCRIPT
(str) The script used by /etc/mail/Makefile to start, stop,
and restart sendmail(8). The default value is
/etc/rc.sendmail. This value should match the
``mta_start_script'' setting in rc.conf(5).
SENDMAIL_SUBMIT_MC
(str) The default m4(1) configuration file for mail submis-
sion to use at install time. The value should include the
full path to the .mc file, e.g., /etc/mail/mysubmit.mc.
Use with caution as a make install will overwrite any
existing /etc/mail/submit.cf.
TOP_TABLE_SIZE
(int) top(1) uses a hash table for the user names. The
size of this hash can be tuned to match the number of local
users. The table size should be a prime number approxi-
mately twice as large as the number of lines in
/etc/passwd. The default number is 20011.
WANT_FORCE_OPTIMIZATION_DOWNGRADE
(int) Causes the system compiler to be built such that it
forces high optimization levels to a lower one. cc(1)-O2
and above is known to trigger known optimizer bugs at vari-
ous times. The value assigned is the highest optimization
value used.
BUILDINGDOCUMENTATION
The following list provides a name and short description for variables
that are used when building documentation.
DISTDIR (str) Where distfiles are kept. Normally, this is
distfiles in PORTSDIR.
DOC_LANG (str) The list of languages and encodings to build and
install.
PRINTERDEVICE (str) The default format for system documentation, depends
on your printer. This can be set to ``ascii'' for simple
printers, or ``ps'' for postscript or graphics printers
with a ghostscript filter, or both.
FILES
/etc/make.conf
/usr/doc/Makefile
/usr/ports/Makefile
/usr/share/examples/etc/make.conf
/usr/share/mk/sys.mk
/usr/src/Makefile
/usr/src/Makefile.inc1
SEE ALSOcc(1), install(1), make(1), src.conf(5), environ(7), ports(7),
sendmail(8)HISTORY
The make.conf file appeared sometime before FreeBSD 4.0.
AUTHORS
This manual page was written by Mike W. Meyer <mwm@mired.org>.
CAVEATS
Note, that MAKEOBJDIRPREFIX and MAKEOBJDIR are environment variables and
should not be set in make.conf but in make's environment.
BUGS
This manual page may occasionally be out of date with respect to the
options currently available for use in make.conf. Please check the
/usr/share/examples/etc/make.conf file for the latest options which are
available.
FreeBSD 10.1 May 28, 2013 FreeBSD 10.1


Systemic lupus erythematosus occurring in a patient with epidermolysis bullosa acquisita.
A dystrophic bullous eruption that met all the criteria for epidermolysis bullosa acquisita (EBA) developed in a 19-year-old woman five years before the onset of clinical and serologic evidence of systemic lupus erythematosus (SLE). Electron microscopic studies of skin lesions both before and after the development of SLE were consistent with the previously reported electron microscopic findings in patients with EBA. Direct immunofluorescence microscopic studies done on bullae before and after the diagnosis of SLE showed linear depositions of immunoglobulin and complement; indirect immunofluorescence microscopic study findings consistently showed no abnormalities. These findings have been noted in other cases of EBA and may implicate autoimmune, immunologic factors in the pathogenesis of the disease process. To our knowledge, the finding of SLE in association with EBA has not been previously reported.


Baur Treffpunkt Extra - one more summer Baur catalog in which the best models of women's clothing of the plus sizes of the season, become the real trends of this summer are presented.

In the catalog models of women's clothing from leading European producers, such as are presented to AJC, by s Oliver, KangaRoos, New Style, Buffalo, m.i.m., Basic World and others.

Also you will find bathing suits and beachwear in the catalog from Lascana.

The clothes for the stout women, presented in the catalog, are fashionable, stylishly practical, convenient and elegant. In Baur Treffpunkt Extra is both evening dresses, and casual clothes in sports style. There are in the catalog jeans clothes, and also things in ethnostyle, sea and romantic styles.

BAUR Treffpunkt Extra is an elegance, style and extravagance. In clothes from BAUR you will look always attractive and womanly, despite a full figure.


Trump kicks off his re-election bid in Florida this week, but the insurgent is now the incumbent. Will his time as president change his strategy?

When Donald Trump launches his presidential re-election campaign this week, he will do it at a rally in the Amway Center – home to sports teams Orlando Magic, Orlando Solar Bears and Orlando Predators – in a part of Florida better known for Cape Canaveral and Walt Disney World.

It will be four years and two days since the property developer and reality TV star descended an escalator at Trump Tower in New York to launch the longest of long-shot campaigns by raging against unfair trade deals and promising to “build a great wall” on the US-Mexico border.

Can Trump win in 2020? This Pennsylvania county may hold the key Read more

He was dismissed. He was scorned. He was laughed at. But he had the last laugh. To the astonishment and consternation of the establishment, Trump went on to offer the ultimate proof that in America, anyone can be president. He beat 16 fellow Republicans, then Democrat Hillary Clinton, to become the first person to reach the Oval Office with no political or military experience.

Now he has to hope that lightning can strike twice. On Tuesday 18 June, Trump, accompanied by the first lady, Melania Trump, the vice-president, Mike Pence and the second lady, Karen Pence, will hold a Make America Great Again rally in Orlando, Florida, a state that is home to his Mar-a-Lago resort and is usually a pivotal battleground in presidential elections.

This time the insurgent is the incumbent, lacking outsider status or shock value, but boasting all the advantages of incumbency, a vast war chest and buy-in from Republican party mandarins. Will he run a more conventional campaign this time? Will he heed the advice of his well-paid advisers? Has the presidency changed him at all?

“Hell no!” said Michael Steele, former chair of the Republican National Committee (RNC). “I remember doing an interview the week of the inaugural and I said my assessment going into this new administration hinges on the answer to a question: will Donald Trump be changed by the presidency or will he change the presidency itself? And the answer is very clear at this point. He has fundamentally changed the presidency of the United States and it will take a man or woman of incredible character to restore it.”

Trump’s 2020 strategy

Back in 2016, which here in Washington feels like millennia ago, Trump ran as a celebrity businessman who glorified in trashing norms and expertise, hurling vulgar insults and sticking two fingers up to the political elite. In 2020, he will run as a celebrity businessman who glorifies in trashing norms and expertise, hurling vulgar insults and flipping off the political elite.

Once a blur on the horizon, the outlines of his next campaign are coming into sharp focus. He has laid out his strategy for re-election in his tweets, his interviews, his speeches and his presidency thus far. It will probably be a rerun of 2016, throwing red meat to red states in a series of high-octane rallies and Fox News interviews that lean in to America’s toxic tribalism.

Most conventionally, Trump and his allies will tout the economy. Trump seldom misses an opportunity to talk about stock market highs, growth topping 3% or unemployment hitting the lowest rate in half a century. The White House relishes recycling old comments from Democrat Nancy Pelosi likening Trump’s tax cuts to “Armageddon” or economist Paul Krugman’s prophecy of “global recession, with no end in sight”.

Ronna McDaniel, current chair of the RNC, told Fox News in May: “The case is gonna be the economy, economy, economy, period.”

Facebook Twitter Pinterest Michael Steele: ‘It’s going to be playing to his nationalistic tendencies because he’s an autocrat at heart and that’s the space he knows and occupies.’ Photograph: Alex Wong/Getty Images

Trump’s speechwriters are also likely to trumpet his two supreme court appointments, bipartisan criminal justice reform and an “America first” approach to foreign policy that he claims defeated Islamic State and brought the North Korean dictator, Kim Jong-un, to the negotiating table. But in the 2018 midterms, Trump tended to veer off teleprompter and trample on his own message.

He talked less conspicuously about the economy than immigration, whipping up fear of caravans from Central America pouring over the border. The nativist message, with its naked appeals to white nationalism at rallies resounding to chants of “Build the wall!”, seems certain to loom large again. Once again, critics say, Trump will adopt the politics of divide and rule, riling up his base rather than broadening his coalition.

“It’s going to be immigration all the time, scaring people about those brown folks coming across the border,” Steele said. “It’s going to be playing to his nationalistic tendencies because he’s an autocrat at heart and that’s the space he knows and occupies. And he’s reinforced now by an attorney general who also believes apparently in the autocracy of an untouchable president.

“So Trump, having been reinforced from a legal perspective, feels that he probably can go out there and keep swinging at the fences on these very delicate issues like immigration, which are tinged with race and xenophobia, and then in between throw in, ‘Yeah, the economy is doing great’. Because the truth of that, as I think the numbers have borne out, is while the economy is strong and GDP is great, most people aren’t necessarily realising the benefit.”

Progressive groups are braced for the onslaught. Maurice Weeks, co-executive director of the Action Center on Race and the Economy, said: “I expect a lot more talk about the wall. I expect a lot more talk about Muslims. I expect a lot more outwardly racist, sexist and homophobic things and that really won’t be a break from anything that’s happened since before he was elected up until now. I think that he’s just going to keep hammering on these things that have maintained his level of support at this scarily high level.”

Weeks added: “He’s never said this meme that we’ve heard from presidents, like after you get elected you’re going to reach across and heal the nation by bringing them together. That’s just not his game.”

Lessons from 2016

Trump’s first campaign thrived as much on what it was against as what it was for. He lambasted the political and media elites and, towards the end of the campaign, kept promising to “drain the swamp”. But enemy No 1 was his opponent, Clinton, whom he branded “Crooked Hillary” as he spoke endlessly about her emails amid chants of “Lock her up!” In 2020, Clinton will not be on the ballot.

Trump already has new ammunition, however. He has been quick to seize on the ascent of self-declared democratic socialists such as the 2020 Democratic candidate Bernie Sanders and millennial New York congresswoman Alexandria Ocasio-Cortez, as well as Democrats’ willingness to contemplate policies such as Medicare for All and a Green New Deal.

Whoever ultimately wins the Democratic nomination, expect to hear a reprise of Trump’s applause line at his 2019 State of the Union address: “We renew our resolve that America will never be a socialist country.”

Facebook Twitter Pinterest Donald Trump at a rally in Harrisburg, Pennsylvania, on 29 April 2017. Photograph: Carlo Allegri/Reuters

Erin Perrine, deputy communications director of the Trump 2020 campaign, said: “Democrats are, by their own admission, embracing socialism. Whoever comes out of the primary, they’re going to be broken, they’re going to be beaten up, they’re going to be saddled with all these policies.”

The red scare tactic was used against Barack Obama in the 2008 election after he suggested that “when you spread the wealth around, it’s good for everybody”, but to little effect. It may gain more traction if Democrats do not choose a centrist as their nominee. John Zogby, a pollster and author, said: “The socialism argument will try to go beyond his base to voters over 65 who do not like his behaviour but remember the cold war and worry the Democratic party may have moved too far left.”

If past is prologue, Trump will also traffic in falsehoods to win, portraying Democrats as favouring “open borders” and – to cement the crucial support of Christian evangelicals – as promoting late-term abortions and even “infanticide”.

He will try to turn the special counsel’s Russia investigation on its head, characterising it as a deep state “coup” intended to thwart the forgotten men and women of America and urging: “Investigate the investigators!” Although he holds the most powerful office in the world, he will revel in grievance and victimhood.

Resources and Russia

Whereas his 2016 campaign had an improvisational let’s-do-the-show-right-here quality, this time it will be a formidable machine that can build a database of supporters and donors. It has already raised more than $100m and hired about 40 staff led by Brad Parscale, a digital guru promising it will “bigger, better and badder” by “every single metric”.

Perrine said: “In 2016, they were building the plane in play but they also managed to land the plane; they did a fantastic job. This will be a campaign befitting an incumbent president. We’re going to have a massive ground game.”

Analysts agree the effort will be professionalised. Henry Olsen, a senior fellow at the Ethics and Public Policy Center thinktank in Washington, said: “It’s not going to be a mom-and-pop campaign like it was in 2016. Tactically, they’ll be much more sophisticated because he’s the incumbent. They will be better staffed with much more resources. He may go off script any time at a rally but the TV ads will be better produced.”

Most infamously, the 2016 election was scarred by the Trump team’s willingness to accept help from Russia, although the special counsel’s report did not identify a criminal conspiracy, despite not entirely exonerating Trump. Could it happen again?

I think after what everyone’s been through over the last three years, you’d have to be a complete idiot to go for something that foreigners provided Henry Olsen

Olsen said: “I think after what everyone’s been through over the last three years, you’d have to be a complete idiot to go for something that foreigners provided. They say once bitten, twice shy. Many people have been scorched and scorched again by this, and they don’t want to have third degree burns.”

But whatever guardrails are put in place, the great unknown is the candidate – capricious, mercurial, sometimes unhinged and always unconventional. Most presidents with his economic numbers would be polling much higher, but Trump’s approval rating has remained stubbornly well below 50%.

Rick Tyler, a political analyst and former spokesman for Ted Cruz’s 2016 campaign, said: “The campaign strategy should be, are you better off today than you were four years ago because, for many Americans, the answer would be yes. That’s what I would run on, but this president is incapable of doing that.

“So far, he’s the victim and everyone’s out to get to him and I don’t know why that would appeal to voters. He has no message discipline, he’s incapable of articulating a vision and his behaviour is obnoxious. All the economic trends point to him winning but he defies convention and I really am sceptical about his ability to cash in.”

Can Trump cash in?

Trump’s tenure in the Oval Office – where chiefs of staff, communications directors and others have come and gone with head-spinning speed – shows he is unlikely to listen to advice from his strategists. Tyler observed: “It bores him. There’s no fight there. He’s wired to fight. He’s got to pick a fight.”

But while the 45th president is notoriously hard to tame, his campaign is likely to remain tightly controlled, hoping to steer him to victory despite himself. Even Trump will not be able to control every ad and social media post going out on his behalf.

They’ll make the case that he’s an asshole, but he’s your asshole Larry Sabato

Larry Sabato, director of the Center for Politics at the University of Virginia, said: “The slogan they will try to sell is ‘You’ve never had it so good’. The campaign surrogates will concede he is obstreperous, outlandish and not a very nice person, and you may not love him, but you love his policies. They’ll make the case that he’s an asshole, but he’s your asshole.”

Like Steele, Sabato does not believe the presidency has changed Trump. “He’s just as obnoxious as when he was elected. In some ways he’s worse because he now has power. He’s not got any better. He hasn’t reached out in any way; we’ve never had a president like that. Every other president has tried to unite the country but he’s a divider, not a uniter.”

Days after Trump’s election, Obama warned “this office has a way of waking you up” and “reality has a way of asserting itself”. But not with Trump. Wendy Schiller, a political science professor at Brown University in Providence, Rhode Island, said: “He’s more self-aggrandising than he has ever been before and he’s gotten away with more,” she said. “But like many other presidents, he has become very focused on winning re-election. He’s not on the golf course as much as in the first year. That’s the only way in which he has changed.”

Some Democrats believe that Trump fluked his way to victory in 2016, losing the popular vote but prevailing in the electoral college based on 77,000 votes across three states, and will not be able to pull off the same trick twice. Bob Shrum, a veteran consultant on several presidential elections, said: “If it’s a rerun of 2016, he will certainly lose because it’s impossible to draw an inside straight twice in those three states, yet he shows no sign of broadening his appeal at all.”

Shrum, a political science professor at the University of Southern California, does think the office of the presidency has altered Trump. “It’s made him worse.

“We have a government undermining the law. It’s dangerous in the sense that he worries about what would happen to him and his family if he doesn’t get re-elected, so he’ll do anything.”

'No idea too lunatic': how Trump's shock troops attack US democracy Read more

Indeed, in 2016 Trump made great play of claiming the game was rigged against him, laying the groundwork so that if he lost, he could cry foul and claim the result would be illegitimate. It is a playbook he may well reach for again, especially if foreign powers seek to interfere. Trump’s spurious claim of “total exoneration” in the special counsel Robert Mueller’s report, and ongoing refusal to condemn Russia for its meddling, is an ominous sign.

Steele, the former RNC chairman, said: “Be afraid, be very afraid, be worried, be very worried, because here again the president has literally gotten away with allowing a foreign government to interfere in our election and his silence – and in some cases standing right next to [Russia’s president, Vladimir Putin] and pretty much putting his arm around saying I believe him over everybody else who has incontrovertible evidence – we should be very worried.

“So 2020 is probably the most unsafe election in our history. We haven’t even begun to seriously drill down on the depths of this … But unfortunately right now we don’t have the leadership in our government that is saying that nor taking steps to to do something about it.”


Brown will be Brooks' top assistant after working for the Nets the past two seasons, including 45 games as their interim head coach. He's also been an assistant with seven other NBA clubs.

Lowe coached the Grizzlies for two-plus seasons and also was an assistant elsewhere, most recently the Timberwolves. He played on of North Carolina State's 1983 NCAA championship team and was the school's head coach from 2006-11.


Get into holiday spirit with Wes Anderson

See the iconic director’s new holiday film for H&M – and find out what Adrien Brody thinks about it.

December 2, 2016

Wes Anderson is at the helm, Adrien Brody plays the lead, and we’re on board a train with strangers.

This year’s holiday film from H&M shares striking similarities with the director’s 2007 masterpiece The Darjeeling Limited – but this time Adrien Brody is not in India nor together with his brothers. Instead he portrays a conductor on a train stuck in a blizzard on Christmas Day, which ultimately forces everyone to delay their holiday plans and celebrate the big day with the people from the neighbouring compartments.

“Setting off by train with Wes was a lovely reminder of our days in Rajasthan together on The Darjeeling Limited. That experience was one of my most cherished memories on location. Shooting on a train creates an intimate and perfect backdrop to tell a story of travels and the unknown. In this case, our train was designed and built from scratch, the carriages are a beautiful canvas for this whimsical Christmas journey," says Adrien Brody.

The carriages are a beautiful canvas for this whimsical Christmas journey

Adrien Brody

Wes Anderson is one of the most notable directors of our time, acclaimed for films such as The Royal Tenenbaums, Rushmore and The Grand Budapest Hotel. He’s known for his great attention to detail, his unique way of working with sounds and colours – and his recurring pool of actors, where one is Academy Award winner Adrien Brody.

"Reuniting with Wes on this H&M film is a little like getting the band back together. He has assembled a tight team of talented and collaborative individuals that he has amassed from across the globe. It feels like one, big (very creative) family reunion. We had a blast bringing Wes' vision to life,” says Adrien Brody.

The theme of the film is “Come Together”, which is exactly what we all need to do as we’re wrapping up yet another year.

“The communal gathering of strangers on a train is a simple yet charming reminder of the holiday spirit. Perhaps the gesture resonates even more at a time in the world where we could all do with giving a stranger a hug,” says Adrien Brody.

H&M’s holiday collection is available in stores and online from the end of November.


CLIPPERS NOTEBOOK: Team knows they need a sense of urgency

This will go down as a record-setting season for the Clippers no matter what they do in the playoffs, but expectations have changed.

Expectations here are grand, and that's why coach Vinny Del Negro hasn't been pleased with his team in a couple of months. The Clippers lost four of five games before Wednesday's home game against Phoenix, which doesn't instill a lot of confidence with six regular-season games left.

"I understand where that comes from," Clippers coach Vinny Del Negro said. "We got off to such a hot start and were undefeated the month of December. Some people say we're complacent because we'd won the division.

"We just haven't played well enough. We have not played at a high enough level consistently enough. No, I'm not hpapy with the level of play, probably since All-Star break."

Players have been talking about the need to perform and get back on track, but those words are ringing hollow.

Tweeted Matt Barnes on Wednesday: "It's time for us to put up or shut up.. The Type of basketball WE'VE been playing lately is gonna have us on vacation in a couple of weeks."

Not exactly. There are two weeks left in the regular season, and the Clippers already have secured a playoff spot and are fourth in the standings. But if they want to improve from last year - in which the Clippers lost to San Antonio in the second round of the playoffs - they'll have to figure out how to get healthy and back in their December groove that had them on a 17-game win streak.

"I haven't seen the urgency overall," Del Negro said. "The guys know that. No one is going to feel sorry for you. You have to go out and stop talking about urgency. Go and do it. Get results."

Chauncey's time?

Chauncey Billups didn't play again Wednesday, but fans should be used to seeing him on the bench in a suit as he's battled mulitple injuries. Billups has played only 20 games because of foot, Achilles, back and groin injuries and isn't even practicing now.

"Hopefully, all these nagging things he has he can get back over (this) weekend and play the last handful of games," Del Negro said. "His minutes have always been monitored. We know what he brings to the team. His health hasn't cooperated."

Moment of silence

The Clippers paid tribute to NBA referee Greg Willard before Wednesday's game with a moment of silence. Willard died Monday at the age of 54 after a battle with pancreatic cancer.


Allen McKnight

Allen Darrell McKnight (born 27 January 1964) is a Northern Irish former international footballer who played professionally in Northern Ireland, Scotland, England, and Hong Kong as a goalkeeper.

Club career
Born in Antrim, McKnight played youth football for a number of local clubs including Crumlin Boys, Crumlin Rec., and Chimney Corner.

He began his senior career in 1984 with Distillery, and he also played for Celtic, Albion Rovers, West Ham United, Airdrieonians, Stockport County, Rotherham United, Walsall, South China and Exeter City.

Celtic
McKnight signed for Celtic in August 1986, joining up again with his former Distillery teammate Anton Rogan who had arrived at Parkhead a few months earlier. He did not feature in any first-team games in his first year, and was loaned out to Albion Rovers to gain experience of the Scottish game. With the departure of Peter Latchford in the summer of 1987, McKnight rose up in the pecking order at Celtic to second-choice keeper, behind first choice Packie Bonner. McKnight played several games for Celtic at the start of season 1987–88 in place of Bonner who had contracted a virus. He made his debut in a 5–1 win away to Dumbarton in a league cup tie on 26 August 1987 and went on to play in three Old firm league games, a 1–0 win at Parkhead, a 2–2 draw at Ibrox and a 2–0 win in the New Year game at Parkhead. Bonner regained his place in the team upon his recovery from illness, but McKnight's 12 league appearances and 5 clean sheets helped the club to win the League Championship.  An injury to Bonner in May 1988 saw McKnight play in the 1988 Scottish Cup Final against Dundee Utd, and he won another winner's medal as Celtic triumphed 2–1 at Hampden. McKnight left Parkhead for West Ham a couple of months later.

West Ham United
During his West Ham United career he was known by the fans as McKnightmare because of his frequent goalkeeping errors. Signed from Celtic in the summer of 1988 McKnight made his West Ham debut on 10 September 1988 in a 1–0 away win against Wimbledon. Competing for the goalkeeper's place with an ageing Phil Parkes, McKnight played all his 23 league games for West Ham in his first season. His last league game coming on 23 May 1989, a 5–1 away defeat to Liverpool which saw West Ham relegated to the Second Division. He had to wait eighteen months for his next game, also a 5–1 defeat, away to Luton Town in the Full Members Cup.

He later played non-league football with teams including Collier Row, Romford and Collier Row & Romford (a merger of his two previous teams).

International career
McKnight earned 10 caps for the Northern Ireland national football team between 1987 and 1989.

Honours
Celtic
Scottish League (1): 1987–88
Scottish Cup (1): 1987-88

References

External links

 NIFG

Category:1964 births
Category:Living people
Category:Association footballers from Northern Ireland
Category:Northern Ireland international footballers
Category:Chimney Corner F.C. players
Category:Lisburn Distillery F.C. players
Category:Celtic F.C. players
Category:West Ham United F.C. players
Category:Airdrieonians F.C. (1878) players
Category:Stockport County F.C. players
Category:Rotherham United F.C. players
Category:Walsall F.C. players
Category:South China AA players
Category:Expatriate sportspeople from Northern Ireland in Hong Kong
Category:Exeter City F.C. players
Category:Romford F.C. players
Category:People from Antrim, County Antrim
Category:Expatriate footballers in Hong Kong
Category:English Football League players
Category:Scottish Football League players
Category:Collier Row F.C. players
Category:Association football goalkeepers


Flyers top Devils 2-1 in shootout

PHILADELPHIA (AP) -- Ilya Bryzgalov made saves in all types of situations - and positions.

Flat on his back, Bryzgalov held off one New Jersey push. Upright on skates, Brzy pushed aside a short-handed surge.

No matter how he stopped the puck, Bryzgalov and the Flyers showed they do indeed have some fight left in their playoff push.

Matt Read and Claude Giroux both scored goals in the shootout to lead the Philadelphia Flyers to a 2-1 win over the New Jersey Devils on Friday night.

The slumping Flyers badly need this win following a 5-2 loss to the Devils on Wednesday. The Flyers are still on the outside of the Eastern Conference playoff race.

''We needed to win a hockey game tonight,'' coach Peter Laviolette said. ''It was something that had to be done. We have to give ourselves a fighting chance.''

Read beat Johan Hedberg on the first shot and New Jersey's Ilya Kovalchuk matched him. Giroux scored the second shootout goal, and David Clarkson and Patrik Elias both failed in their attempts against Bryzgalov.

Max Talbot scored in regulation for the Flyers and Clarkson had a goal for the Devils.

Bryzgalov stopped all 10 shots in the first period and a whopping six in the 5-minute overtime.

''We had a couple good chances,'' Kovalchuk said. ''But The Bryz was playing real well tonight.''

The Flyers' penalty kill, which staved off a 5-on-3 in the first period, was clutch in the closing minutes of regulation. Brayden Schenn was whistled for charging with 1:42 left, but the Devils couldn't convert. They attacked Bryzgalov and one puck got loose and trickled just outside the post, that had Flyers fans gasping as the final seconds ticked off.

With every man advantage or easy looks, the Devils just couldn't convert.

With Bryzgalov flattened in the crease, Marek Zidlicky failed to flip the puck into the open the net. Zidlicky just didn't enough lift on his shot and pushed the puck smack into a sprawled out goalie.

''I think I need a bigger curve, probably,'' Zidlicky said.

No doubt, the Flyers had to have this one.

Flyers general manager Paul Holmgren ripped the team in a 15-minute meeting at practice Thursday. He then gave Laviolette a vote of confidence and said he hadn't considered firing him. Holmgren demanded the Flyers play hard and with purpose for all 60 minutes.

With every point so crucial, the Flyers got the message.

''I think we played much harder than we did the last game,'' forward Danny Briere said. ''We won a lot more battles.''

Holmgren's gamble to dismantle the Flyers after a run to the 2010 Stanley Cup finals has yet to produce a roster capable of a deep postseason run. Jeff Carter, Mike Richards, James van Riemsdyk were all traded and Bryzgalov has been maddeningly inconsistent in his two seasons in net.

The Flyers entered the night five points behind Winnipeg for the final playoff spot in the East.

Unlike Briere, Bryzgalov said there were more reasons than Holmgren's speech for the inspired play.

''We all are realizing how important every game is for us, every point,'' Bryzgalov said. ''It's not because someone walked in said, 'If you don't start playing better we're going to kill you.'''

Playing with the spirit they needed more of in this underachieving season, the Flyers played one of their better first periods of late.

With Philadelphia's Jakub Voracek in the penalty box for hooking and Wayne Simmonds serving time for roughing, the Devils had the early two-man advantage.

Bryzgalov came up with a pair of clutch stops, first on a pad save against Kovalchuk and then holding off Clarkson on the rebound. Bryzgalov heard a well-earned rousing ovation for keeping the Devils off the scoreboard.

''We had some chances, but you have to give Bryzgalov some credit,'' coach Peter DeBoer said. ''He made some really big saves and they were playing for their life out there.''

The Flyers backed up Bryzgalov when Talbot punched the puck in a wide-open net with Hedberg drawn out to the tip of the crease for a 1-0 lead. Simon Gagne was open on the wide side and made a perfect pass to Talbot on the low circle.

That left the Devils down a goal - and a player - and the end of one. The Devils lost center Andrei Loktionov for the game with an undisclosed injury after only 4:04 of ice time.

New Jersey tied it 1-all when Bryce Salvador's shot from the point was redirected by Clarkson for his 11th goal. Kovalchuk rang one off the post toward the end of the period. Salvador headed for the bench in the first after he was smacked blocking a shot.

The Flyers did enough to beat their division rivals. They'll need more of the same to make the playoffs.

''Sadly, we've put ourselves in a rough spot,'' Briere said. ''There's no other way around it. We're not going to be allowed to drop too many games from here going out.''

NOTES: The Devils fell to 3-1 vs. the Flyers this season. ... The Flyers don't have another home game until March 26. ... The Flyers blocked 16 shots. ... Hedberg said he'd be ready to handle back-to-backs and play against Montreal on Saturday night.


Q:

Python: How to make Reportlab move to next page in PDF output

I'm using the open source version Reportlab with Python on Windows.  My code loops through multiple PNG files & combines them to form a single PDF.  Each PNG is stretched to the full LETTER spec (8.5x11).
Problem is, all the images saved to output.pdf are sandwiched on top of each other and only the last image added is visible.  Is there something that I need to add between each drawImage() to offset to a new page?  Here's a simple linear view of what I'm doing -
WIDTH,HEIGHT = LETTER
canv = canvas.Canvas('output.pdf',pagesize=LETTER)
canv.setPageCompression(0)

page = Image.open('one.png')
canv.drawImage(ImageReader(page),0,0,WIDTH,HEIGHT)

page = Image.open('two.png')
canv.drawImage(ImageReader(page),0,0,WIDTH,HEIGHT)

page = Image.open('three.png')
canv.drawImage(ImageReader(page),0,0,WIDTH,HEIGHT)

canv.save()

A:

[Follow up of the post's comment]
Use canv.showPage() after you use canv.drawImage(...) each time.
( http://www.reportlab.com/apis/reportlab/dev/pdfgen.html#reportlab.pdfgen.canvas.Canvas.showPage )
Follow the source document(for that matter any tool you are using, you should dig into it's respective website documentation):
http://www.reportlab.com/apis/reportlab/dev/pdfgen.html


/****************************************************************
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 * or more contributor license agreements.  See the NOTICE file *
 * distributed with this work for additional information        *
 * regarding copyright ownership.  The ASF licenses this file   *
 * to you under the Apache License, Version 2.0 (the            *
 * "License"); you may not use this file except in compliance   *
 * with the License.  You may obtain a copy of the License at   *
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 *                                                              *
 * Unless required by applicable law or agreed to in writing,   *
 * software distributed under the License is distributed on an  *
 * "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY       *
 * KIND, either express or implied.  See the License for the    *
 * specific language governing permissions and limitations      *
 * under the License.                                           *
 ****************************************************************/
package org.apache.james.protocols.lib.netty;

import org.apache.james.util.concurrent.JMXEnabledThreadPoolExecutorMBean;

public interface JMXEnabledOrderedMemoryAwareThreadPoolExecutorMBean extends JMXEnabledThreadPoolExecutorMBean{

}


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Public Citizen Calls for 12 States to Investigate Insurers’ Use ofQuestionable Arbitration Firm

Insurance Commissioners Asked to Probe Firm Led by Disbarred Lawyer Consumer Group Also Seeks Investigation of Homebuilder Insurer

DENVER – Public Citizen has asked state insurance commissioners to investigate whether insurance companies have been improperly requiring homebuyers to arbitrate disputes using Construction Arbitration Services (CAS), a private firm that hears cases over defects in new homes. In letters released today, Public Citizen describes how CAS is co-owned by a former lawyer who was disbarred for stealing client funds and operates in apparent violation of 12 states’ laws.

The letters also request investigations of the Home Buyers Warranty (HBW) companies, which insure many homebuilders and have designated CAS as the sole legal forum available to tens of thousands of Americans who buy new homes each year.

Arbitration is a private legal system that is usually less favorable to consumers than the court system. The HBW companies have selected CAS to arbitrate cases filed against them, despite CAS’s co-ownership by Marshall Lippman, who was disbarred by the state of New York in 1997. Lippman has said to a Texas state legislator that CAS arbitrates such disputes in all 50 states — even though 11 states prohibit arbitration clauses in insurance contracts.

In addition, CAS is refusing to comply with California’s law requiring disclosure of all arbitration outcomes, according to a letter to Public Citizen signed by CAS’s other owner, Lester Wolff.

“Mandatory arbitration is already skewed against consumers even without the involvement of dishonest persons or illegal operations,” said Jackson Williams, legislative counsel for Public Citizen. “When arbitrators are selected by the business defending the lawsuit, the arbitrator’s bias will be to rule in the business’s favor or award less than full damages. In this instance, we see that the HBW companies have very low loss ratios, indicating that CAS may allow them to systematically deny or underpay valid claims from homeowners.”

Public Citizen’s letter to the commissioners in the four states where HBW companies are domiciled—Colorado (where HBW is headquartered), Hawaii, Nevada and Virginia—asks that HBW’s claims procedures be scrutinized for these patterns of unfair practices.

The letter tells commissioners that “Lippman’s position in CAS is analogous to that of a supervisory judge in a court system. If you are one of the many thousands of Americans who buy newly constructed homes each year, Mr. Lippman wields more influence over your life than the Chief Justice of the United States. It is simply shocking that someone with this record of dishonesty has been entrusted by insurers with so much power.”

Additional letters to commissioners in 11 states where arbitration clauses are banned from insurance contracts – Arkansas, Georgia, Hawaii, Kentucky, Louisiana, Nebraska, Oklahoma, South Carolina, South Dakota, Virginia and Washington – ask that those laws be enforced against HBW and CAS. Another letter asks California’s commissioner to order HBW and CAS to comply with that state’s disclosure law.

Another way that CAS arbitration is uniquely disadvantageous to consumers is CAS’s policy of making consumers pay the entire cost of the arbitration process – $500 or more. All other major arbitration providers limit the consumer’s filing fee to $375 or less, making the business that selects arbitration pay the biggest share of the cost.

The letters were made public at today’s session of the Insurance Regulatory Examiners Society (IRES) annual conference, held in Denver. One of the IRES conference workshops is devoted to the issue of mandatory arbitration. IRES members, who staff the various state insurance departments, are in the front lines of insurance regulation and have authority to conduct the investigations requested by Public Citizen.

Individuals who have feel they have been adversely affected by an unfair arbitration clause and are willing to be contacted by Public Citizen or enforcement authorities should e-mail their information to jkutch@citizen.org.

Public Citizen, Inc. and Public Citizen Foundation

Together, two separate corporate entities called Public Citizen, Inc. and Public Citizen Foundation, Inc., form Public Citizen. Both entities are part of the same overall organization, and this Web site refers to the two organizations collectively as Public Citizen.

Although the work of the two components overlaps, some activities are done by one component and not the other. The primary distinction is with respect to lobbying activity. Public Citizen, Inc., an IRS § 501(c)(4) entity, lobbies Congress to advance Public Citizen’s mission of protecting public health and safety, advancing government transparency, and urging corporate accountability. Public Citizen Foundation, however, is an IRS § 501(c)(3) organization. Accordingly, its ability to engage in lobbying is limited by federal law, but it may receive donations that are tax-deductible by the contributor. Public Citizen Inc. does most of the lobbying activity discussed on the Public Citizen Web site. Public Citizen Foundation performs most of the litigation and education activities discussed on the Web site.

You may make a contribution to Public Citizen, Inc., Public Citizen Foundation, or both. Contributions to both organizations are used to support our public interest work. However, each Public Citizen component will use only the funds contributed directly to it to carry out the activities it conducts as part of Public Citizen’s mission. Only gifts to the Foundation are tax-deductible. Individuals who want to join Public Citizen should make a contribution to Public Citizen, Inc., which will not be tax deductible.

To become a member of Public Citizen, click here. To become a member and make an additional tax-deductible donation to Public Citizen Foundation, click here.


Use of psychoactive substances among Zagreb University medical students: follow-up study.
To estimate the exposure of Zagreb University medical students to psychoactive substances in 2000 and compare it with data collected in 1989. Students were surveyed in 2000 (n=775) and 1989 (n=986) by means of a self-reporting questionnaire. The 2000 survey also included 136 non-medical students. General demographic data and data on experience with psychoactive substances were collected, analyzed, and presented as percentages with 95% CI. The lifetime prevalence of contact with illicit drugs (mostly marijuana) among medical students in 2000 was 35% vs 14% in 1989. Repeated use was reported by 3.9% students, and 6% confirmed the experience of simultaneous use of alcohol and drugs. The lifetime prevalence of contact with psychoactive medications (mostly benzodiazepines) was 33% in 2000 vs 15% in 1989. Medications were largely used without medical supervision, with 3.5% of the students explicitly stating non-medical reasons for consumption. The prevalence of smokers was 29% in 2000, compared with 31% in 1989, and prevalence of regular alcohol consumers (on monthly, weekly, or daily basis) was 50% vs 52% in 1989. Experience with all types of substances was more present among senior students, and less among medical students than their "non-medical" peers. Regular alcohol use was associated with the experience of illicit drugs use. In 2000, 40% of medical students and 53% of "non-medical" students voted for legalization of marijuana. Experience with psychoactive substances is common among Zagreb medical students. Experiences with illicit drugs and psychoactive medications have substantially increased over the past decade.


Fourth Squad detectives are investigating a Robbery that occurred in Lakeview on Friday, May 2, 2014 at 12:15 a.m.

According to detectives, a male victim, age 22, was walking home south on Cleveland Street in the vicinity of Glenwood Road when he was approached by 3 male blacks (no further description). The suspects turned the victim around and one subject displayed a black handgun in his waistband. The other subjects removed property from the victim. The subjects fled north on Cleveland Street onto Sylvan Drive. No injuries were reported.

Detectives ask anyone with information regarding this crime to contact Nassau County Crime Stoppers at 1-800-244-TIPS. All callers will remain anonymous.

Detail by: D/Lt. Decicco/ 4th Sqd 05/02/2014/0955/6574

*** UPDATE ***

Fourth Squad detectives report the arrest of Jeremy Freeman, 18, of 818 Harrison Street, Lakeview and Tylik Wilson, 18, of 515 Grant Avenue, West Hempstead in connection with the above incident. Both defendants were located on Eagle Avenue and Woodfield Road in Lakeview on 05/02/2014 at 6:50 pm and were placed under arrest.

Freeman is charged with Robbery 1st Degree and Resisting Arrest. Wilson is charged with Robbery 1stDegree and Assault 3rd Degree. Both defendants will be arraigned in First District Court, Hempstead on 05/03/2014.


This past weekend was Creative Action’s huge fall event I Spy Pie! located at Central Market. The weather was perfect for the family-fun activities offered such as crafts, games, face painting, live music, and of course, pie tasting!

The festivities kicked off at noon including a wonderful performance by the Emmy Award winning duo The Biscuit Brother’s, who did a great job getting the children up off their feet singing and dancing along to the music. One of my favorite parts of the performance was when they had a song about watermelons and needed a participant to count to ten in a language other than English. An adorable little girl stood up, took the microphone and started counting in Arabic and Chinese. It was very impressive.

By 12: 30 p.m., people were lining up to get their tickets to taste the wonderful pies that were offered by Central Market Bakery, Central Market Cooking School, Madison Street Desserts, Tiny Pies and Texas Pie Kitchen. Many UT student organizations, including Tower PR, were there to volunteer at the craft and pie tasting booths.

The two awards up for grabs were Judges Favorite and the People’s Choice. After everyone tasted the contestant’s pies, they were able to cast their vote for which they thought had the tastiest pies. Our three celebrity pie tasting judges Jim Swift, Nina Seely and John Bullington, Executive Chef had a really hard time awarding their favorite pie. They were all so delicious!

The enthusiasm at the event was lively and appetites for pie were at an ultimate high. As the pies underneath the tasting tent began to dwindle down to only crumbs, the awards were announced. Tiny Pies won the People’s Choice award for their delicious Bourbon Buttermilk Chess pie and Madison Street Desserts took home the Judges Favorite award for their Meyer Lemon Meringue pie (which was my personal favorite too!)

It was an amazing day for everyone and how could it get better when we get to taste the best pies in town! A huge thanks to Central Market and all of the bakeries involved for their support towards a great cause!

Creative Action (formerly Theatre Action Project) needs your pie-ness. This is creativeness with all things pie for our fall fundraiser,I Spy Pie! Saturday, October 20th at Central Market North. If you’re ready to roll up your sleeves and have fun and help us select the best pie in Austin, we’d love to have you sign up to volunteer. The event features fun family activities, arts and crafts for all ages, pie tastings, and bragging rights for the best pie in Austin. Sign up for 1 or 2 shifts. It’s easy as pie!

PS: My favorite pie is lemon meringue. I have a very distinct memory of being kid crying about something on my back porch and the next door neighbor lady had just made a fresh lemon meringue pie. No more tears after that!


Besides reading over the scriptural overview of the Menorah, we discussed what the possible significance of various details of the menorah, such as; The number of candlesticks, the almond tree detailing, it's position in the tabernacle and the fact that it is made of a sold, hammered work.Of course like other elements of the Tabernacle, the menorah is a shadow of good things to come- Jesus/Yeshua!(Hebrews 10:1, Colossians 2:17)Just as the priests needed the menorah and the light it gave to preform their duties unto YHWH, so it is with Yeshua. No one can come to the Father except through Him. Without the light from the menorah the priests would be in utter darkness and unable to find their way to the Father.(See John 1:6-9, John 8:12, John 14:6-7)Shalom shalom!!The HUB


Browse Nearby

General Info

Hours

Monday:

Closed

Tuesday:

12:00pm - 9:00pm

Wednesday:

12:00pm - 9:00pm

Thursday:

12:00pm - 9:00pm

Friday:

12:00pm - 9:30pm

Saturday:

12:00pm - 9:30pm

Sunday:

12:30pm - 9:00pm

About Us

You can’t go wrong with Chinese food, and now with our on-line ordering you’ll have it quick and easy too. Taste the flavours of stir frys that combine meats, poultry and seafood with the seasoning and spices that make Chinese food a favourite the world over. Vegetarians can also join in the goodness with their own selections that feature the same attention to taste.


Today's Paper
» NATIONAL
» ANDHRA PRADESH

SP’s complaint: police yet to register case

VISAKHAPATNAM: The police are yet to register a case on the complaint filed by Srikakulam Superintendent of Police Ch. Srikant, two days after he lodged a complaint against Deputy Inspector General (Visakha Range) Soumya Mishra.

It’s learnt that the officials are holding parleys with the two IPS officers to solve the issue amicably as registering a case would sully the image of the Department. Nonetheless, both officers and staff of the department expressed the view that it was “unbecoming on the part of the DIG to behave in that manner”. They were also sympathetic to Mr. Srikant, whom they view as a sincere officer and a ‘sensitive officer’.

It’s learnt that the police who had obtained a legal opinion to avoid booking of a case under the SC/ST Atrocities (Prevention) Act against the DIG were also planning to go for a second opinion from the designated court on the issue.

Meanwhile it’s learnt that Police Commissioner N. Sambasiva Rao, who is inquiring into the complaint, has recorded the statements of the Srikakulam SP, the DIG and another IPS officer Vinit Brij Lal. Mr. Sambasiva Rao is expected to submit his report to the DGP on Tuesday.

Controversies have dogged IPS officer Soumya Mishra’s career. During her stint as SP of Vizianagaram, a constable attempted suicide as she reportedly beat him up over some issue. The Labour Department had registered a case as child labour was employed at her house in the past.


Fast investigations from biological matrices using CE--test of a blood-brain barrier model.
In order to adopt a general workflow for complex biological matrices with respect to a new blood-brain barrier (BBB) model, a micellar electrokinetic chromatography method has been developed. The cells forming the BBB have been cultivated in a special cell growth medium in which six drugs (acetaminophen, caffeine, carbamazepine, cimetidine, indometacin and propranolol) have been dissolved and tested for their penetration properties. The results showed good to very good accordance to the reference values. Samples were directly injected onto the capillary without any pretreatment (fused silica capillary, id: 50 μm, L: 48 cm, l: 40 cm). After method development, separations were carried out using a 60 mM borate buffer containing 200 mM of SDS at 30 kV, leading to an analysis time of less than 10 min. Between two runs the capillary was rinsed with a mixture of equal parts of running buffer and isopropanol (70% v/v), which proved to be very effective to remove matrix compounds. An appropriate choice of the detection wavelength (220 or 254 nm) could avoid major interferences between analytes and matrix. The typical RSD% for migration times was approximately 2%, for peak areas, it ranged from 2 to 6%, which was very well acceptable for the generic method used in this study and the low concentrations investigated. The LODs ranged from 10 to 30 ng/mL.


Q:

Getting Brilliantretail and Freeform Pro to play nice

So I was forwarded here by Solspace since this is apparently their "paid" support now for Freeform Pro users :P
c&p of my questions I posed to them:
I recently ran across a project that requires me to make an order form. I'm currently using BrilliantRetail for the storefront, and then a special member groups gets to expedite things using an order form as apposed to going through a standard checkout process.
I have this, somewhat, working with Freeform Pro and am hoping to get a little more help to finish things up.
What I'm doing now is populating the form with channel entries (really br_products, but it works the same). Each product has an qty option associated with it, which is simply a text field in the Freeform form. Now, I'm sort of getting the data I need, but not the details.
So I have a field named qty, then each product produces a tag like this:
<input id="qty" type="number" name="qty[]" value="" />

So the quantity gets passed along but I also needed the Title, SKU, and Price. So I added three hidden fields for this, and added this to my template:
<input id="title" type="hidden" name="title[]" value="{title}" />
<input id="sku" type="hidden" name="sku[]" value="{sku}" />
<input id="price" type="hidden" name="price[]" value="{price}" />

So this also works, but I'm getting product info for products not ordered (because all the hidden fields are now filled in they all get returned, not what I want). What I need to do is only see the "title", "sku", and "price" for products that actually have "qty" filled in. This is my problem, I don't know how to do this??
My idea was using data-attributes for the "qty" input, so the data is attached to the product being ordered, but I don't know how to do this??
Hoping someone here can help me figure this out! Thanks in advance!!

A:

So I, sort of, answered my question. Which only led to more questions!! See here: Solspace Freeform custom fieldtype and notifcation templates


// Copyright 2019 The Chromium Authors. All rights reserved.
// Use of this source code is governed by a BSD-style license that can be
// found in the LICENSE file.

#ifndef THIRD_PARTY_BLINK_RENDERER_CORE_CSS_CSSOM_CROSS_THREAD_UNPARSED_VALUE_H_
#define THIRD_PARTY_BLINK_RENDERER_CORE_CSS_CSSOM_CROSS_THREAD_UNPARSED_VALUE_H_

#include "base/macros.h"
#include "third_party/blink/renderer/core/core_export.h"
#include "third_party/blink/renderer/core/css/cssom/cross_thread_style_value.h"
#include "third_party/blink/renderer/platform/wtf/casting.h"
#include "third_party/blink/renderer/platform/wtf/text/wtf_string.h"

namespace blink {

class CSSStyleValue;

class CORE_EXPORT CrossThreadUnparsedValue final
    : public CrossThreadStyleValue {
 public:
  explicit CrossThreadUnparsedValue(const String& value) : value_(value) {}
  ~CrossThreadUnparsedValue() override = default;

  StyleValueType GetType() const override {
    return StyleValueType::kUnparsedType;
  }
  CSSStyleValue* ToCSSStyleValue() override;

  std::unique_ptr<CrossThreadStyleValue> IsolatedCopy() const override;

  bool operator==(const CrossThreadStyleValue&) const override;

 private:
  friend class CrossThreadStyleValueTest;

  String value_;
  DISALLOW_COPY_AND_ASSIGN(CrossThreadUnparsedValue);
};

template <>
struct DowncastTraits<CrossThreadUnparsedValue> {
  static bool AllowFrom(const CrossThreadStyleValue& value) {
    return value.GetType() ==
           CrossThreadStyleValue::StyleValueType::kUnparsedType;
  }
};

}  // namespace blink

#endif  // THIRD_PARTY_BLINK_RENDERER_CORE_CSS_CSSOM_CROSS_THREAD_UNPARSED_VALUE_H_


The Kinship of Private Equity and Small Business

“Every business is founded with the primary purpose of creating profit.” – Jim Blasingame, internationally recognized thought-leader on small business and entrepreneurship.

(PRWEB) June 14, 2012 –Mitt Romney's record in the private equity industry has become part of the election year political debate.

Weighing in with a passive-aggressive swipe, Steven Rattner, a former private equity executive and Barack Obama's "car czar" and loyal supporter, said in a television interview, "Bain Capital – like other private equity firms – was founded and managed for profit ... earned legally and legitimately. Any job creation was a welcome but a secondary byproduct."

In an article published on Forbes.com, and an associated video, internationally recognized small business expert Jim Blasingame reveals that Rattner, and others who say or infer that there is something wrong with the "profit first – jobs second" motivation, should understand that this is the same strategy of small businesses.

"As essential as employees are to accomplishing a business founder’s wealth-creation goal, no pre-start-up entrepreneurial dreamer ever thought, 'I want to commit all of my time, energy and resources – and risk everything – so I can create jobs,'" writes Blasingame. "Jobs are not just the byproduct of private equity firms and small businesses, they are the byproduct of capitalism – period."

Blasingame is available to discuss the historical and contemporary importance of the "profit first – jobs second" business motivation.

For an interview on the role of private equity in creating U.S. jobs, contact Davonna Hickman, 888-823-2366,dsb(at)jbsba(dot)com, to book Jim Blasingame.

ABOUT JIM BLASINGAME

Jim Blasingame is an internationally recognized thought-leader and expert on small business and entrepreneurship. He is president of Small Business Network, Inc. and creator and award-winning host of the nationally-syndicated, weekday radio program, The Small Business Advocate® Show since 1997.

In addition to his syndicated radio show, which is simulcast worldwide on the Internet, Blasingame is the author of two books and a syndicated columnist for newspapers, Forbes.com, Nasdaq.com, OPENForum.com and American City Business Journals. He is a high-energy keynote speaker on small business issues and the 21st century marketplace.


A close-up of the ESCRTs.
The ESCRT protein complexes assemble on the endosome into a protein network that sorts ubiquitinated transmembrane proteins into lumenal vesicles of the compartment. New structural information highlights the complexity of the ESCRT network.


Q:

Mac 10.8 bash_profile work weird

I follow some "setup cocos2dx and android on mac" tutorial. When I come to setup .bash_profile, I am ask to create .bash_profile and edit:
export COCOS2DX_ROOT=~/Documents/Cocos2dx/cocos2d-2.1rc0-x-2.1.2
export ANDROID_SDK_ROOT=/Users/Documents/Android/adt-bundle-mac-x86_64-20130219/sdk
export ANDROID_NDK_ROOT=/Users/Documents/Android/android-ndk-r8e
export NDK_ROOT=/Users/Documents/Android/android-ndk-r8e
export PATH=${PATH}:${ANDROID_NDK_ROOT}
export PATH=${PATH}:${ANDROID_SDK_ROOT}

after restart terminal:
echo $COCOS2DX_ROOT
export/AS/Documents/Cocos2dx/cocos2d-2.1rc0-x-2.1.2
cd $COCOS2DX_ROOT
export: No such file or directorycos2dx/cocos2d-2.1rc0-x-2.1.2

I have no idea how the "export" go into the path. I have tried "~/..." and "/User/..."(full path). But all go wrong.

A:

Somehow the lines got entered into your .bash_profile incorrectly - it looks like maybe a newline got removed somehow. Edit your .bash_profile again and ensure that it looks like what you posted above. Save and restart your terminal session, and you should be OK.


Q:

Clojure: How to add scalar type in lacinia Graphql schema in edn format?

I want to define scalar type such as Token
if I define Token in following format it fails to compile
:scalars
  {:Token }

According to https://lacinia.readthedocs.io/en/latest/custom-scalars.html , I need to give parse and seririase functions
So I have modified code below,
 :scalars
   {:Token
     {:parse #(str %)
      :serialize #(str %)
     }
   }

Now I am getting error as " No dispatch macro for: ("
How I can define scalar type token as "scalar Token"?

A:

Like nha says in the comments, you can't have function literals in edn files. If you move this to a .clj file it'll work.
If you do want to keep the schema as an .edn file though, there's the function com.walmartlabs.lacinia.util/attach-scalar-transformers for that.
schema.edn:
{,,,
 :scalars
 {:Token {:parse :token-parser
          :serialize :token-serializer}}}

schema.clj
(ns foo.schema
  (:require
   [??? :refer [slurp-edn]]
   [com.walmartlabs.lacinia.schema :as schema]
   [com.walmartlabs.lacinia.util :as util]))

(def transforms
  {:token-parser #(,,,)
   :token-serializer #(,,,)})

(defn schema []
  (-> (slurp-edn "schema.edn")
      (util/attach-scalar-transformers transforms)
      ;; ... attach resolvers, compile schema, etc
      ))