30))/((-1044)/580)?
-2/47
88/(-539)*(-3339)/(-212)
-18/7
Evaluate (1295/(-1036))/((-2)/4 + 258/576).
24
((-6)/(-20) - (5 - (-4660)/200))*57/2622
-14/23
What is the value of 1*(-248)/2619 + -138*224/(-417312)?
-2/97
155454/2028 + -76 + (-10)/4
-24/13
What is 1648/224 - 1*14*(-12)/(-24)?
5/14
104/20 + 165312/2240 + 36
115
What is the value of -117 + 126/((-32508)/(-37066))?
80/3
((-68)/(-136))/(-4*2/288)
-18
Evaluate 22*5/10 + ((-2)/27 - 11).
-2/27
Evaluate 17 + 2 + -62 + 29.
-14
Calculate (-2487)/(-28186)*(-187)/(-110).
3/20
What is the value of (7/(-14) - 2/(-4)*11) + (-174 - -133)?
-36
What is the value of (-70)/(-24)*(-10140)/33800?
-7/8
Calculate -27 - (-56 + 59)*-6.
-9
(-2 - 3) + (13452/(-1900) - -12)
-2/25
What is -10 + (-37 - 3627/(-124) - 3/12)?
-18
What is 5 + 129/27 + -10 + (-202)/(-18)?
11
Calculate 240/75 + (-56)/56.
11/5
Calculate ((-15)/525)/(((-8)/(-192)*-4)/((-13)/(-13))).
6/35
(-7866)/(-230) - (46/80 - 6/16)
34
Evaluate -5*(-2)/12 + 16700/(-80)*6/1395.
-2/31
Calculate 1 - -1 - ((-85932)/1071)/(-31).
-10/17
3 - ((-2)/(-34)*-138 + -2 - (-38)/323)
13
What is 2/48*(-3100 + 3108)?
1/3
What is -10 - (-22 + 4) - ((28/6 - -2) + 2)?
-2/3
Calculate (-8)/54*54/(-36) - ((-8520)/54 + 8).
150
What is the value of ((-309)/7830 - 338/(-19604))/(-2)?
1/90
What is (-1 + -1 - (0 - 1))/(24 - 530600/22120)?
-79
What is the value of (124/168 - -1) + 45/(-9) + 50/15?
1/14
What is -10 + 3033/81 - (-10 - (-765)/81)?
28
What is the value of ((-45)/5 + 6)*((-5766)/527 + 11)?
-3/17
Evaluate 2 + 35/(-2) - (-95)/12160*64.
-15
(17/510*-153)/((-15)/(-25))
-17/2
Evaluate ((-9)/160)/(4355/325 - 14).
3/32
Evaluate (-739)/(-9) - ((-40)/(-100))/((-24)/140*-21).
82
Calculate 34 - 35/(-1820)*-52.
33
-43 + 3920/(185 - 105)
6
What is (-2)/(-3 - -5) + ((-4896)/(-66) - (-160)/(-880))?
73
(-28197)/9399*(-3*6/(-27) + (-13)/18)
1/6
Evaluate 2/(-4)*20/(-45) - (-3740)/99.
38
What is the value of -11 + ((-15)/6)/(-5 + (-27)/(-6))?
-6
Evaluate 176/24*384/(-176).
-16
-8 + -7*35880/(-13230) + 11/(-1)
-1/63
Evaluate (-9)/288*2188 - (494/304 + -1).
-69
What is the value of (24854/(-172) + 98)*(3 - 5)?
93
14/(-48)*(-1496)/154*-42
-119
Evaluate ((-125)/2375)/(-4*5/36860).
97
Calculate (2 - -8)/((-405)/5508).
-136
Evaluate 119 - (-1727661)/(-15252) - (-92)/(-16).
-1/41
Calculate 83426/(-2323) + (16/276)/((-12)/18).
-36
Calculate (-17 + (-39729)/(-2318))*128/1088.
1/61
What is 4/76 - 34/1615*2710?
-57
What is (264/(-1200))/(70/(-700)) + 342/(-10)?
-32
What is the value of 2*-2 - (3 + (-3278)/1078 + 21043/539)?
-43
Evaluate 22/(-539) + 92462/73206.
11/9
What is the value of (0 - -31) + 12308/(-476) - ((-1)/(-7) - 0)?
5
Evaluate (-17 + 1700/102)*(-20)/72*1/(-5).
-1/54
What is (-970)/(-15326)*101/(-505)?
-1/79
What is the value of (24 - (3302/(-127) + 1344/49))*7/(-2)?
-79
2 + (-39)/20 + 463/6482*(-38241)/30
-91
What is (-2200)/(-150)*(-21)/28?
-11
-8 + -2 + 0 - (-111)/((-23976)/(-528))
-68/9
((-287)/(-80))/7 + (3996/(-180) - -22)
5/16
What is the value of (36/(-33))/((-610)/(-3355))?
-6
What is the value of 640/224*147/(-66) - (-12)/33?
-6
What is the value of 10 + -11 - 10 - (-3465)/33?
94
What is (-2262)/(-104)*(-10)/45 + (-2)/(6/(-15))?
1/6
Calculate 110 - 97 - (-201)/(-15) - (-38)/20.
3/2
What is the value of 33*(-39)/(-1144)*(43 - (10 - -9))?
27
Evaluate -38 - ((-31 - -71) + -58).
-20
What is 80/(-28) + 53120/17920?
3/28
Evaluate -13 + ((-2656)/64 - -54).
-1/2
Calculate (3 - 0)*16833/1629.
31
What is (-1)/(-7 + (331200/1475)/32)?
-59
Evaluate (-192)/(-40)*19*85/102.
76
What is the value of 12/(-13 + 50/(15750/4165))?
54
Calculate (175/28 - 5)*12*(-2470)/475.
-78
What is (-3872)/(-154) + 33 + -67?
-62/7
(164/(-17))/(207/((-151317)/86))
82
Evaluate ((-17)/(9027/30))/((6380/264)/29).
-4/59
(38/(-114) + (-15)/(-36))*-171 - -14
-1/4
Calculate (6 - -82)/8 + 1647/(-27).
-50
What is the value of (((-81)/(-399))/27*7/(-2))/((-24)/144)?
3/19
What is ((-282093)/5130 - -50) + (1 - 2) + 6?
1/90
What is the value of (-45)/(-792)*360/200 + (18/33)/2?
3/8
(18/11)/((-476)/68 - -8)
18/11
Calculate (19351/(-6276) + 33/12)*-13.
13/3
What is (-62)/(-7) - 3322/(-1057)?
12
Calculate 2/(-59) + (-582777)/(-18408) + -31.
5/8
Evaluate ((-3374)/(-483) + -1 + -6)/(7/14).
-2/69
-77 - 91 - -103 - (-4 - 2/(-1))
-63
Evaluate 85/935*40 - (4 - 2).
18/11
31502/1311 + -5 + 874/(-46)
2/69
What is the value of -10 - ((3808/60)/(-8) + 5 + 160/(-24))?
-2/5
What is the value of (-148507)/(-1067) - ((-1846)/7029 - (-4)/9)?
139
What is the value of ((28 - 3) + -23)*(-55)/(-88)*(-60)/(-1)?
75
What is 1/2 - -36*((-200)/6 + (19 - -14))?
-23/2
What is (1303674/(-90954))/(1/6)?
-86
75/3 + ((-1737)/15)/(7613/1655)
-4/23
What is the value of 3/27 + ((-24025)/279 - 6) + (2 - 2)?
-92
What is the value of 2 - -1 - (49/(1372/(-252)) + 16)?
-4
What is ((-28)/(-3) + -1)*(-2677 + 2674)?
-25
Calculate -13*(-1 + 0) - (3125/5000)/((-440)/(-8384)).
12/11
What is (2/(-5))/((11396/(-220) - -54)*4/22)?
-1
Calculate (-2)/60 - 3014746/(-100380).
30
(2*(3 + -2))/(20723/(-530) - 195/(-5))
-20
Evaluate (-67 - 5352/(-80))/((-182)/(-35)).
-1/52
((-8772)/170 + 51)*345/63
-23/7
What is the value of ((-81)/54)/((-710)/(-12)*((-553)/(-70) + -7))?
-2/71
Calculate 22*3 + 41837588/(-633989).
2/223
((-396)/176*12/54)/(264/(-32))
2/33
What is ((-750)/(-3500))/((36 - 38)/(-1 + -531))?
57
(-3989 - -3979)*(-4)/10
4
Calculate ((-3 - -6) + -11 + (-185)/(-25))/((-26)/(-20)).
-6/13
What is the value of (2/11 - (-192)/880)/((-1106)/1120 + 1)?
32
Evaluate ((-154)/847 - 1096/264)/(3/(-63)).
91
Calculate 31 + -31 + 44/(-3) + (-24)/((-720)/(-10)).
-15
What is the value of (-6 - -13) + (-13)/((-858)/(-450)) - (-592)/11?
54
What is the value of 6/(-4)*(-240)/42*1176/(-11340)?
-8/9
Calculate 11122/6700 + 3/(-2).
4/25
Evaluate 2/(-7)*(5040/470)/(-72).
2/47
What is (-691)/(-24185) - (-2242)/(-70)?
-32
What is the value of ((-559)/86)/((-39)/12)?
2
What is the value of (6 - 4)*(-11 - -14) - (-140)/(-26)?
8/13
Calculate (-114)/(-494)*(-520)/(-144).
5/6
What is 3 + 38/(-7) - 225/(-525) - (-112 - -5)?
105
What is (1148/(-504) + 464/261)/((2/(-140))/(-1))?
-35
What is the value of 3260/652*(-3)/42?
-5/14
Calculate (-18)/(-42)*7 - (0 + (-440)/(-104)).
-16/13
Evaluate 11 - (((-22)/(-165))/((-3)/(-9)) + 3773/455).
30/13
What is (-25 - (1 + -1))/((-144)/(472032/1490))?
55
What is the value of (-118 + 181 + -65)*((-183)/(-6))/1?
-61
Evaluate 22/220 - 38/(-60)*3 - (16 - 5).
-9
What is the value of -67 + 24862/372 - 346/12?
-29
(13/(39/6))/((-168)/(-532)) + -2
13/3
Evaluate (-96)/594*57/76*11/(-30).
2/45
Evaluate ((17340/153)/17)/((-3)/((-36)/(-88))).
-10/11
Evaluate 6/20*25110/(-85374).
-3/34
Calculate (183/468)/((-30)/(-16)) - (-48 + (-30366)/(-630)).
1/117
What is the value of (406/8)/((-4662)/(-4440)*40/(-48))?
-58
Calculate (-5 - 6773/(-1183))/((-166)/(-2158)).
66/7
Calculate 228 + -134 + -104 - (1 - 19).
8
(230/(-10))/(105/95 + 4 + 312/(-76))
-23
Calculate (-11)/((-198)/240)*16*(-93)/992.
-20
Calculate 1069965/32240 + 15/(-80).
33
Evaluate (4 + 36/(-28))*(63 - -392)/13.
95
Evaluate (-2275)/(-52) + (-18)/(-8)*(-38)/(-342).
44
Calculate (68/10)/((1856/(-160))/(-29)).
17
Calculate (-1285)/1542*516/16985.
-2/79
What is 18/(-81) + (6*1 - 27700/4950)?
2/11
(-4)/((-252)/15*(-8400)/3024)
-3/35
What is (-8 - (-187)/30) + 584/365?
-1/6
Evaluate (5 - 44/10) + (40/(-160) - 1394/(-360)).
38/9
What is 16611/(-11319) - (-6)/21*189/42?
-2/11
(-1398)/36*312/(-156) - 3/(-9)
78
What is (420*90/2835)/((-4)/(-3) - 2)?
-20
(72/((-156)/(-13)))/(21/(-161))
-46
574/(-410)*45 - -39
-24
Evaluate 2/(-174)*37149/(-17934)*-24.
-4/7
What is the value of ((-400)/56 + 62764/7952)/(25/12 + -2)?
9
What is (40/(-128)*8 - ((-157)/6 + -5))*-3?
-86
What is (20 - -1) + 233 + -226 - (-7 - -1)?
34
What is the value of (-1002)/68 - (-2757)/(-187476)?
-59/4
Calculate (-110)/(-14) + (1 - 2) - (-505)/(-1818)*18.
13/7
Evaluate -20 + 222/9 + (-23)/6.
5/6
Evaluate (-12712)/931 + (-50400)/(-3528).
12/19
Calculate (5/(-6)*(-4)/26)/(14 - 3992/288).
12/13
Evaluate 36 + ((-150)/(135/27) - -50).
56
(-116 - 5) + (-38 - (-65 - -42))
-136
What is (24*(-120)/1728)/(1670/(-12))?
2/167
What is 36/(-28)*27720/(-1080)?
33
Calculate ((-7040)/(-200))/(36/45 - 0) + -13.
31
What is -130 + (12 + (-25)/2)/(((-150)/84)/25)?
-123
What is (-1 + 14/8


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House Democrats are threatening to force Trump administration officials’ compliance with their impeachment inquiry by targeting something they hold dear: their paychecks.

Democrats have twice referenced using an obscure provision in the annual Financial Services spending bill, referred to as Section 713, that says any federal employee who “prohibits or prevents, or attempts or threatens to prohibit or prevent” another official from communicating with lawmakers shouldn’t be paid during that time.

The process for carrying out such a threat is relatively simple. First, lawmakers request a Government Accountability Office investigation, after which the GAO would issue a legal opinion on whether administration officials have blocked certain federal employees from testifying or otherwise communicating with lawmakers or their aides.

If any wrongdoing is found, the GAO would inform the relevant agency and suggest it claw back salary paid during that time. The agency would then seek repayment from the offending federal employee — if timely payment wasn’t made, it could be sent to a collection agency.

The relatively unknown provision has rarely been used during its 22-year history, with at least two key exceptions.


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Industries

GUELPH, Ont.—A new report from Food and Beverage Ontario (FBO), the association representing Ontario’s food processors, says exports from Ontario have increased 12 per cent since 2013 to $7.6 billion per year.

The organization says this indicates that Ontario’s 3,000 food processors are export-oriented.

However, over the same period imports to Ontario increased by 20 per cent to $14.1 billion annually.

“We have learned from this report that there is opportunity for Ontario processors to replace imported finished products, commodities and ingredients, especially as the recent softening of the Canadian dollar assists our processors with more competitive pricing,” said Norm Beal, CEO, Food and Beverage Ontario.

It is important to note that trade agreements such as CETA and TPP have the potential to open significant new markets through removal of market tariffs and non-tariff barriers.

The Ontario food and beverage processing industry contributes more than $40 billion in revenue to the provincial economy. Together, food and beverage manufacturing and agriculture generate more revenue annually than the province’s motor vehicle manufacturing sector.

“This industry finds itself at the right time and the right place. We have a trade imbalance that can be nimbly corrected with the addition of new hires to maximize capacity utilization, new product and packaging innovation and marketing support that targets both domestic and export consumers,” says Michael Burrows, Treasurer of FBO and CEO of Maple Lodge Farms.

Canadianmanufacturing.com is the top source of daily industry-focused news in Canada. We cover the world for stories that impact your business each day with news, in-depth articles and expert commentary.

Cleantech Canada delivers the latest news and insight on the global green economy. Our award-winning editors and expert contributors connect businesses and entrepreneurs with information on cleantech financing, market development and growth strategies.

Find it on Frasers, your home for sourcing industrial suppliers of manufactured products, MRO equipment and components, and so much more.

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REDWIRE is News you can use from Leading Suppliers. Why? Suppliers realize that B2B Buyer behavior has changed and so must they.

Fact is buyers are doing a lot more upfront online research as part of their buying process today. Leading Suppliers want to support this buying process with useful facts, insights and newsworthy content – goes well beyond your typical press release or web site content.

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Introduction {#s0001}
============

During exercise-induced bronchoconstriction, an osmotic stimulus of the airway epithelium leads to a cascade of biomarker release from several inflammatory cells.[@cit0001] Controversy remains about the causative mediators in the bronchoconstrictive response to exercise in asthma, but there is clear evidence for mast cell activation during exercise-induced bronchoconstriction in asthmatics.[@cit0002] Mast cells and eosinophils release cysteinyl-leukotrienes (Cys-LT) and prostaglandins which are the most well-known mediators of exercise-induced bronchoconstriction.[@cit0003] Increased level of leuktrieneE~4~ (LTE~4~) in urine has been shown in several studies[@cit0004],[@cit0005] and explains the protective role of montelukast against exercise-induced bronchoconstriction.[@cit0006] Although the role of type 2 (T2) mediators in exercise-induced bronchoconstriction is not well characterized, it has been shown that sputum eosinophil percentage correlates to severity of exercise-induced bronchoconstriction,[@cit0007] and that increased serum periostin level predicts a positive exercise challenge.[@cit0008] In addition, polymorphism of the T2 cytokine IL-13 has shown to be associated to the severity of exercise-induced bronchoconstriction.[@cit0009] Thymus and activation-regulated chemokine (TARC) is associated with the allergic inflammation of asthma and has shown an inverse correlation to FEV1 in children with a positive response to exercise.[@cit0010]

Even though several T2 biomarkers are known to be associated with exercise-induced bronchoconstriction, the T2 response per se has not been described during exercise. The aim of this study was therefore to investigate T2 biomarkers (IL-13, TARC, periostin and Cys-LT) in plasma and urine from subjects with asthma and healthy controls before and after an exercise challenge.

Methods {#s0002}
=======

Subjects {#s0002-s2001}
--------

Twenty-two subjects with mild asthma (according to Gina guidelines)[@cit0011] and 18 healthy controls were investigated (see [Table 1](#t0001){ref-type="table"}). The controls had no respiratory symptoms or diagnosed asthma. All subjects were non-smokers without respiratory tract infection within three weeks prior to the investigation. All asthmatic subjects refrained from using β~2~-agonists and inhaled corticosteroids for at least 48 h before the study. The study was conducted in accordance with the Declaration of Helsinki and the Regional Ethical Review board in Lund approved the study. All subjects gave informed consent.Table 1Subject Characteristics and Baseline Biomarker Concentration in PlasmaHealthy Controls,\
n=18Asthmatics,\
n=22p-valueAge, years25 (22--35)26 (24--33)0.76Sex (male/female), n9/912/100.78^a^Atopy, n4120.04^a^FEV~1~, l4.0 (3.3--4.7)3.8 (2.9--4.5)0.67FEV~1~, %p101.3 (94.3--111.8)95.2 (87.5--109.4)0.25Positive exercise test, n190.013^b^Fall in FEV~1~ during test, %4.6 (0.0--6.8)6.1 (3.0--18.8)0.067ICS, n015\<0.001^b^FeNO, ppb15.8 (9.5--35.1)21.8 (15.1--37.3)0.31Biomarkers in plasma IL-13, pg/mL491 (413--104814)767 (352--12472)0.81 TARC, pg/mL75 (52--248)70 (19--98)0.26 Periostin, pg/mL495 (361--748)522 (329--857)0.76 Cys-LT, pg/mL559 (509--660)646 (521--815)0.23[^1][^2]

Study Design {#s0002-s2002}
------------

At arrival in the clinic, participants emptied their bladder and drank a glass of water. Atopy was defined as having a positive skin prick test (ALK-Abello, Hørsholm, Denmark) of airborne allergens (including house dust mite (*D. pteronyssinus* and *D. farinae*), cat, horse, dog, *A. alternata, C. herbarum*, grass, birch and ragweed pollen). Thereafter, exhaled NO was measured, spirometry performed and blood and urine samples were taken just prior to the exercise test. An exercise challenge test was performed and thereafter the subjects were resting for 60 min while repeated spirometry was performed (at 5, 10, 15, 20, 30, 45 and 60 min after the end of the exercise challenge test) and blood and urine samples were collected repeatedly (plasma samples were collected after 10, 30, 45 and 60 min, and urine samples were collected after 30 and 60 min).

Exercise Challenge {#s0002-s2003}
------------------

The exercise challenge test was conducted (as previously described)[@cit0012] on a treadmill: a) two minutes of running: speed and slope were set to increase the heart rate of the subject to approximately 90% of maximum capacity (defined as 220 beats per minute -- age in years), b) four minutes of running: at about 90% of maximum capacity, c) two minutes of running: the speed and slope were increased to induce a maximum exertion. A positive exercise test was defined as having ≥10% fall in FEV~1~ after the exercise challenge test.

Forced expiratory volume in 1 second (FEV~1~) was measured using a flow-volume spirometry (Jaeger MasterScope, Würzburg, Germany) and FEV~1~% predicted (%p) was calculated according to Crapo.[@cit0013]

Fractional Exhaled Nitric Oxide (FeNO) {#s0002-s2004}
--------------------------------------

FeNO measurements were performed at baseline using a NIOX Flex (Aerocrine, AB, Stockholm, Sweden). Patients were comfortably seated; inhaled NO depleted ambient air and exhaled at a flow rate of 50 mL/s. The manoeuvre was performed 3--4 times.

Biomarker Analysis {#s0002-s2005}
------------------

For biomarker analyses, ELISA kits from R&D systems (Abingdon, UK) were used to measure IL-13 (DY213), TARC (DY364) and periostin (DY3548B) and kits from Cayman Chemicals (Ann Arbor, MI) were used to measure CysLT (500 390) and LTE4 (501 060). All urine samples were corrected for creatinine.

Statistical Analyses {#s0002-s2006}
--------------------

All statistical calculations were performed using SPSS 25.0 for Windows (SPSS, Inc., Chicago, IL). Due to non-normally distributed data, all statistical analyses were done using non-parametric tests; Mann--Whitney U-test for unpaired data, Wilcoxon signed-rank test for paired data, Friedman test for repeated measures and correlations were calculated by Spearman correlation test. Chi square test was used for number comparisons, with Fisher's correction when necessary. A p-value of \<0.05 was considered statistically significant.

Results {#s0003}
=======

Baseline Characteristics {#s0003-s2001}
------------------------

Asthmatics and controls showed similar levels of IL-13, TARC, periostin and Cys-LT in plasma at baseline ([Table 1](#t0001){ref-type="table"}). Similarly, there were no differences in baseline levels between subjects with a negative and positive exercise challenge, between atopic and non-atopic subjects, or between subjects with or without inhaled corticosteroid treatment.

Plasma T2 Biomarkers After Exercise Challenge {#s0003-s2002}
---------------------------------------------

In plasma, there was an increase over time in interleukin-13 (IL-13) in all subjects (p\<0.001) during the 60 min following the exercise challenge ([Figure 1A](#f0001){ref-type="fig"}), with a peak at 10 min after the exercise challenge in both the asthmatic and control group (p=0.05 from pre to 10 min) and thereafter a decrease back to baseline again (from 10 to 30 min: p=0.011, and from 30 to 60 min: p =0.065).Figure 1Relative change in plasma levels of IL-13 (**A**), TARC (**B**), periostin (**C**) and Cys-LT (**D**) before (pre) and 10, 30 and 60 min after an exercise challenge test in controls and asthmatics. Medians and interquartiles are presented. \*\*\*=significant change over all time points in all subjects with p\<0.001 according to Friedman test.

An increase in thymus and activation-related chemokine (TARC) in plasma was also seen over all time points (p\<0.001), but only in the control subjects ([Figure 1B](#f0001){ref-type="fig"}). The increase in TARC in the control subjects peaked at 10--30 min after the exercise challenge, and the relative increase in TARC was significantly larger at both 10 and 30 min in the controls compared to the asthmatics (p=0.037 and 0.022, respectively).

Periostin in plasma did not change in either the asthmatics or in the controls after the exercise challenge ([Figure 1C](#f0001){ref-type="fig"}). In contrast, Cys-LT in plasma showed an overall decrease in all subjects (p\<0.001) during the 60 min following the exercise challenge ([Figure 1D](#f0001){ref-type="fig"}), and this decrease was seen in both asthmatics (p=0.040) and controls (p\<0.001).

Urine T2 Biomarkers After Exercise Challenge {#s0003-s2003}
--------------------------------------------

In conjunction with plasma, the level of IL-13 was increased in urine 30 min after the exercise challenge ([Figure 2A](#f0002){ref-type="fig"}, p=0.002). This increase was uniform in all samples that had detectable levels at baseline (n=10: 6 controls and 4 asthmatics), and decreased again at 60 min compared to 30 min (p=0.004). Similarly, leukotriene E~4~ (LTE~4~) was increased in urine samples (all: p\<0.001), with a peak at 60 min ([Figure 2B](#f0002){ref-type="fig"}). This increase was most pronounced in asthmatic subjects (p\<0.001), but was seen also in controls (p=0.008). TARC was not detectable in urine in any of the subjects. Periostin was detectable in urine from only a few subjects (n=7) at different time points. Although a tendency towards a decrease over time was discerned in these individuals, the trend was not significant (data not shown).Figure 2Urinary levels of IL-13 (**A**) and LTE~4~ (**B**) before (pre) and 30 and 60 min after an exercise challenge test in controls and asthmatics. Medians and interquartiles are presented and significant changes in all subjects are shown as \*\*=p\<0.01 and \*\*\*=p\<0.001 according to Wilcoxon signed-rank test.

Correlation Analyses of T2 Biomarkers {#s0003-s2004}
-------------------------------------

Baseline plasma levels of IL-13 correlated to baseline plasma levels of Cys-LT, TARC and periostin. In addition, baseline plasma levels of Cys-LT correlated to baseline plasma levels of TARC (see [Table 2](#t0002){ref-type="table"}). These associations remained at 10, 30 and 60 min after the exercise challenge. In addition, baseline levels of IL-13 and LTE~4~ in urine correlated significantly (r=0.66, p=0.027).Table 2Correlations Between Baseline Values of the Respective Biomarkers in Plasma or UrinePlasmaIL-13TARCPeriostinTARC**r=0.59, p=0.001**periostin**r=0.43, p=0.019**r=0.24, p=0.14Cys-LT**r=0.58, p=0.001r=0.33, p=0.040**r=0.27, p=0.087**Urine**IL-13TARCPeriostinPeriostinr=0.61, p=0.14n.d.LTE~4~**r=0.66, p=0.027**n.d.r=−0.45, p=0.85[^3]

In plasma, there was an inverse correlation between the change in TARC and the change in CysLT from baseline to 10 min after exercise (r=−0.47, p=0.050) within the healthy subjects (and almost significant from baseline to 30 min; r=−0.043, p=0.076) which was not seen within the asthmatics.

When investigating correlations between plasma and urine levels, there were no correlations between plasma and urine levels for any of the biomarkers during baseline. Though, after the exercise challenge test, IL-13 levels in plasma correlated at most time points to the post test levels of IL-13 in urine (r=0.77--0.81 and p=0.005--0.009).

There was no correlation between the levels of Club cell protein 16 (CC16), which are previously published,[@cit0012] and IL-13.

FeNO in Relation to T2 Biomarkers {#s0003-s2005}
---------------------------------

FeNO is a biomarker that most often reflects T2 status, and in this study a correlation between FeNO and baseline IL-13 concentrations in urine (r=0.68, p=0.029) was shown. This reflects to some extent a relationship between FeNO and T2 status, even though FeNO did not correlate to any of the other biomarker levels in plasma or urine at baseline. The levels of FeNO did however correlate clearly to urinary LTE~4~ at 60 min (r=0.57, p=0.001), and a non-significant tendency could be seen already at baseline and at 30 min.

There was no difference in FeNO between subjects with and without inhaled corticosteroids or between subjects with a positive and a negative exercise test.

Discussion {#s0004}
==========

In both plasma and urine, there was an increase in IL-13 after the exercise challenge in both the asthmatic and control group. Our finding of a rapid increase in IL-13 after exercise in all subjects could be linked to an endothelial response due to the increased cardiac output, and/or an epithelial response due to osmotic stress. There was however no correlation between IL-13 and the levels of CC16 (from previous publication)[@cit0012], which may suggest a different location of the response with a focus on the bronchial instead of bronchiolar segments. Seeing as IL-13 has previously been shown to be a mediator of normal epithelial repair,[@cit0014] epithelial release of IL-13 in response to exercise-induced osmotic trauma could be a useful physiological response. Moreover, IL-13 levels in plasma after the exercise challenge test correlated at most time points to the post test levels of IL-13 in urine. This reflects a homogenous systemic increase, and might be due to a non-metabolized excretion of IL-13.

The correlations seen between most of the T2 biomarkers at both baseline and later time points suggest a uniform baseline T2 status in the individuals. In addition, correlations also after the exercise challenge imply a coherent increase in T2.

The increase in plasma TARC in healthy controls, but not in asthmatics, could suggest an inadequate T2 response due to exercise in asthmatics. Furthermore, the decrease in CysLT in response to exercise was evident in both healthy controls and asthmatics, even though it was most prominent in healthy controls. In addition, the inverse correlation between the change in TARC and change in CysLT during the first 10 min was present only in the healthy controls, suggesting a common T2 response to exercise that was maybe pathologically impaired in asthmatics. This was separated from the IL-13 response since no correlations were found between change in IL-13 and change in TARC or CysLT.

In urine, there was a distinct increase in LTE~4~ after 60 min, while the levels of CysLT in plasma decreased. In a previous publication,[@cit0005] we have shown a small but significant decrease of LTE~4~ in urine in athletes after exercise, which can also be discerned in the healthy subjects in the present study. The decrease of CysLT after exercise seen in plasma in this study is in conjunction with the decrease of LTE~4~ seen in urine in that study.

The correlations between FeNO and leukotriene levels in urine suggest a common cellular source of FeNO and Cys-LT, tentatively the mast cells that are known to be involved in the process of exercise-induced bronchoconstriction.

When investigating all subjects, no differences were found between individuals with a negative and positive exercise challenge, between atopic and non-atopic subjects, or between subjects with or without inhaled corticosteroid treatment. If these analyses would have been investigated within an asthma group, there might have been other results. Unfortunately, we have too few subjects and do not have the power to do these sub-groupings.

Only mild asthmatics were included, which can explain the lack of any difference between asthmatics and controls and the response would maybe be different in a group of patients with more severe asthma. Many of the asthmatics were on daily treatment with mild/moderate dose of inhaled corticosteroids which might have impeded a T2 response in these asthmatics. There were though no difference in baseline levels or response to exercise in asthmatics with inhaled corticosteroids compared to without. Another limiting factor might be accuracy of the assays. For example, periostin has several isoforms that are involved in a variety of biological processes. A precise and well-characterized assay for detecting periostin is needed to be able to correctly analyze functional aspects of periostin, or the ability of periostin as potential biomarker in physiological and pathological conditions.[@cit0015]

In conclusion, circulating levels of IL-13 were increased after exercise to the same extent in asthmatics and healthy controls, which indicates a physiological rather than a pathophysiological response. In contrast, TARC in plasma was increased, but only in healthy controls, and CysLT in plasma was decreased after exercise, but increased in urine.

Disclosure {#s0005}
==========

None of the authors have any conflicts of interest related to the manuscript content.

[^1]: **Notes:** Data are presented as median (IQR) or number. Atopy was defined as having a positive skin prick-test of airborne allergens. Positive exercise test was defined as having ≥10% fall in FEV1 after the exercise challenge test. p-value= statistical difference between healthy controls and asthmatics using Mann--Whitney U-test, Chi^2^-test^a^ or Fisher's Exact test^b^.

[^2]: **Abbreviations:** FEV~1,~ forced expiratory volume in 1 s; ICS, inhaled corticosteroids; FeNO, fractional exhaled NO at flow 50 mL/s.

[^3]: **Notes:** Unit for all plasma biomarkers is pg/mL, and unit for all urine biomarkers is pg/mg creatinine. Significant correlations are shown in bold.


For indispensable reporting on the coronavirus crisis, the election, and more, subscribe to the Mother Jones Daily newsletter.

When you add up the true costs of junk mail —paper, printing, delivery, and disposal (44 percent winds up in landfills unopened)—you get 51.5 metric tons of greenhouse gases each year, the equivalent of 11 coal-fired plants or 9.4 million cars. But while there’s been a national Do Not Call registry since 2003, Congress has yet to do the same for paper solicitations. The USPS, in concert with the Direct Marketing Association, has successfully stalled efforts in at least 18 states to create Do Not Mail registries; Postmaster General John Potter has argued that “nothing is more targetable than the mail…And you don’t have to worry about filters.” The environmental group ForestEthics has launched an online petition (at DoNotMail.org) to push Congress to heed the majority of Americans (nearly 90 percent, according to a 2007 Zogby poll) who favor a registry; more than 64,000 have signed so far. For now, the junk-mail averse can remove their addresses from some lists via sites like GreenDimes.com—and by contacting individual credit card companies, magazines, and other businesses.


import Vue from 'vue';
import api from '../../api';
import * as types from '../mutation-types';

// const localStorageglobal.localStorage;
// const JSONglobal.JSON;

export default {
  state: {
    counts: {
      count: 0,
      unread_count: 0,
    },
    index: {
      notifications: {
        lists: [],
        pagination: null,
      },
    },
  },
  mutations: {
    NOTIFICATION_COUNTS_INIT: (state) => {
      Vue.set(state.counts, 'count', 0);
      Vue.set(state.counts, 'unread_count', 0);
    },
    NOTIFICATION_COUNTS_GET_DATA_SUCCESS: (state, { data }) => {
      Vue.set(state.counts, 'count', data.count);
      Vue.set(state.counts, 'unread_count', data.unread_count);
    },
    NOTIFICATION_INDEX_GET_LISTS_SUCCESS: (state, { data, pagination }) => {
      if (pagination.current_page === 1) {
        Vue.set(state.index.notifications, 'lists', []);
      }
      const lists = state.index.notifications.lists.concat(data);
      Vue.set(state.index.notifications, 'lists', lists);
      Vue.set(state.index.notifications, 'pagination', pagination);
    },
    NOTIFICATION_GET_ENTITY_SUCCESS: (state, { data }) => {
      Vue.set(state, 'entity', data);
    },
  },
  actions: {
    notificationCountsGetData({ commit }) {
      api.notification_get_counts().then((response) => {
        commit(types.NOTIFICATION_COUNTS_GET_DATA_SUCCESS, response.data);
      });
    },
    notificationIndexGetLists({ commit }, page) {
      api.notification_get_lists(page).then((response) => {
        commit(types.NOTIFICATION_INDEX_GET_LISTS_SUCCESS, response.data);
      });
    },
    notificationDeleteEntity({ commit }, id) {
      api.notification_delete_entity(id).then((response) => {
        commit(types.REQUEST_SUCCESS, response.data);
      });
    },
    notificationGetEntity({ commit }, id) {
      api.notification_get_entity(id).then((response) => {
        commit(types.NOTIFICATION_GET_ENTITY_SUCCESS, response.data);
      });
    },
    notificationMarkAsRead({ commit }) {
      api.notification_mark_as_read().then((response) => {
        commit(types.REQUEST_SUCCESS, response.data);
      });
    },
  },
};


first of all i wanna say thanks for this app, its really good, better than other nds emulators out there

so my problen right now is that i cannot save in-game if i do in any sloth and overwriting the main one, the game will close.. not even reseting!

and i cant save or quicksave too!, if i do they will IMEDIATLY gets deleted and replaced by the last 2 saves, i went to "manage savefiles" and its looks normal and it looks like these 2 savefiles have google drive backup.. so i delete them both and i go to the main menu, and BAM!!, they are there in the folder!, its like i cant overwrite them, delete them ... so i tried to move the actual files and start to look for solutions like moving the savefiles to other folders across my sdcard or my phone memory; i empty the savefiles folders and it wont let me create new savefiles.. it will get deleted right away.. so it did not work, the games runs normal, (one of my fav NDS and i have played the GBA version too).. so i can play it regular but i cant neither save in game or out game nor quicksaves...

another fact i have not played games since july of the last year.. and i think there was an update.. not big difference..then now i went back to play some FFTA GoR, and now this happens to me...

im really sad right now i putted over 130hours i need help to save my savefiles

i have a samsung galaxy s5 , but the sdcard i rooted from a samsung galaxy s2 skyrocket since 2015, so my s5 is not rooted all the way, only my sdcard, i did not wanted to unrooted because there is some exelent phone cleanup apps ("SDmaid pro" is the name) that help my phone memory to get clean due of "you cant install games AND STORE THEIR DATA IN YOUR SDCARD."

so i cant tell if because i stop playing my games and installed the new update, or my rooted sdcard will be interfering with the new updated, because i had this savefiles for a year and nothing happened, i start playing when i got my s5, i couldnt run it in my s2.. too laggy


Q:

Troubleshooting a DIY Ion Thruster

Been following a Make-Magazine article on how to make your own ion thruster:
https://makezine.com/projects/ionic-thruster/
Went through the tutorial step by step, not seeming to get any thrust out of my thruster. I've checked the conductivity between the nails and the copper wire, they all conduct. I've checked the conductivity between each copper tubing piece and the copper wire, they all conduct.  The distance between the nails and the copper tubing looks about the same at it is in the tutorial.
One suggestion I had is that my nails aren't perfectly perfectly centered, but I'm not sure if there's anything else besides this that leads to this setup not putting out any thrust.
Caution: Do not try this at home! It uses a 30 kV AC neon light power supply.
I've followed the instructions in this video, including the recommendations for safety:

Here's my build following the tutorial:

A:

The instructional video shows a 30kv transformer providing the electromotive force for the ion engine/desk fan.
The user-created make video provides a clear reading of a 10kv transformer. That appears to be a strong indicator for lack of strength in the build.
Chuck up a set of nails in an electric drill and sharpen the points as suggested by uhoh, then pump up the volume... oops, increase the voltage with a more powerful transformer.
The tutorial video suggests a one-inch spacing for the exhaust nozzles. The maker video appears to be proportionally similar, but I suspect that no harm would come from bringing the ion destination a bit closer to the emitter. Not too close, perhaps another five to six millimeters.
It's difficult to fathom science in Imperial units, but these videos show that it works too.

A:

I very strongly suspect the sharpness of the points on the nails is key. This relies on field ionization of the air, and that is caused by points on the nails sharp enough so that electric fields near the tip are sufficiently high (of order volts/Angstrom) that they will either rip an electron off of individual molecules or atoms in the air producing positive ions, or add an extra electron producing negative ions.

Field desorption (FD) is a method of ion formation used in mass spectrometry (MS) in which a high-potential electric field is applied to an emitter with a sharp surface, such as a razor blade, or more commonly, a filament from which tiny "whiskers" have formed.

See also for example:

electrostatic fluid acceleration; physical principles
air ionizer
electrostatic precipitator

Separating the electron from a neutral atom or molecule is hard work and usually has low efficiency. In real ion thrusters for space application, the majority of the weight and power consumption are a result of the ionizing aspects of the design, rather than the acceleration aspects.
You'll need to find a way to either sharpen the nails, or produce some whiskers on them. I think this was omitted from the tutorial you are following.

below: Slide 52 from Ion sources Ionization and desorption methods explains that the extremely strong field of order 1E+10 V/m needed to ionize atoms is obtained by a needle at 10 kV potential when the radius of curvature of the tip is decreased to 10 microns. As long as the distance to ground is large, it matters very little if it's 1cm or 10cm. From the point of view of the field at the sharp tip, that's nearly infinity. Almost all of the potential drop happens in the first millimeter or so, and the field is only high enough to ionize atoms or molecules at the very tip.

Field Emission Electric Propulsion (FEEP)
This principle is also used in some designs for electric thrusters for small spacecraft. The implementation is a little different though. Instead of a metal point in a gas, the needle is hollow and a liquid propellant is introduced into the capillary space. When there is a high field, the liquid naturally forms a cusp or point called a Taylor cone. Individual atoms will become ionized and leave the surface.
When operated differently, the Taylor cone will reach a mechanical instability and ionized droplets will be formed. This is called Electrospray ionization and is distinct from a field ionization ion source.
Here's one example of an electrospray thruster with an array of microfabricated sharp points.

Field-emission electric propulsion (FEEP) is an advanced electrostatic space propulsion concept, a form of ion thruster, that uses liquid metal (usually either caesium, indium or mercury) as a propellant. A FEEP device consists of an emitter and an accelerator electrode. A potential difference of the order of 10 kV is applied between the two, which generates a strong electric field at the tip of the metal surface. The interplay of electric force and surface tension generates surface instabilities which give rise to Taylor cones on the liquid surface. At sufficiently high values of the applied field, ions are extracted from the cone tip by field evaporation or similar mechanisms, which then are accelerated to high velocities (typically 100 km/s or more).


In a statement, Qantas said that about 65 per cent of the misclassified employees had missed out on one or more benefits owed to them, such as rostered days off or overtime.

Majority 'better off overall'

But most staff were also overpaid their base rates and received bonuses to which they would not have been entitled.

"In total, the majority of people (83 per cent) were better off overall than they would have been under the agreement, due to higher base salaries and bonuses," the airline said in a statement.

"Qantas will not recover money paid in excess of the agreement and has grandfathered current benefits (such as higher base salaries and bonuses) as well as adding entitlements required by the enterprise agreement, such as rostered days off."

The total staff underpaid their entitlements has blown out by more than 10 times since the airline first detected the errors in February last year.

At the time, Qantas said it had misclassified about 220 workers and that just 55 workers, on about $90,000 a year, were underpaid.

Unlike other major employers, such as Coles and Spotless, the airline failed to reveal the updated underpayment total in its earnings results last month, despite initiating its review more than a year ago and signing the enforceable undertaking with the regulator about a week later.

A spokesman said at the time that the underpayment was probably not material and that the overpayments exceeded the underpayments.

In its 2019 annual report, Qantas said the misclassifications had resulted in cuts to its executive bonuses.

The FWO's enforceable undertaking requires Qantas to conduct an independent review to determine whether there are further underpayments and if so, to pay an even higher contrition payment of 7 per cent, plus $2000 per employee. It must conduct audits for the next three years.

Despite describing the underpayments as "significant", Ombudsman Sandra Parker said an EU was appropriate after Qantas proactively notified the FWO and fully cooperated with the investigation.

“This independent analysis will reduce the burden on the Fair Work Ombudsman, and subsequent cost to the taxpayer, for ensuring that Qantas back-pays its staff correctly," she said.

“Viewed together, the back-payment bill, interest paid on underpayments, additional payments made to impacted staff and contrition payment impose a significant cost on Qantas."

However, Australian Services Union assistant secretary Linda White criticised the regulator's agreement as an incentive to underpay workers given Qantas made "record profits" and "significant earnings" during the period.

“If you can steal $9 million, which would have earned millions in interest over that period and only get fined $390,500, companies will keep doing it, because they profit from the practice," she said.

Ms White said Qantas had "deliberately put in place processes to avoid the enterprise bargaining agreement by abandoning the standard HR practice of having position descriptions attached to jobs, opening the door to underpayments".

“This was not a misclassification or ‘bungle’ – it was a deliberate and systemic abuse of workers."

Qantas Group executive Rob Marcolina said that the airline had put "a lot of resources into calculating the full impact, fixing it for those affected and putting systems in place to make sure it doesn’t happen again".

"We realise this type of conduct by companies doesn’t meet community expectations, and it doesn’t meet our own commitment to our people or compliance."

Qantas must rectify the underpayments by April 24 and complete the external review of the underpayments by October 14.


/**
 * Copyright (c) 2015-present, Facebook, Inc.
 * All rights reserved.
 *
 * This source code is licensed under the BSD-style license found in the
 * LICENSE file in the root directory of this source tree. An additional grant
 * of patent rights can be found in the PATENTS file in the same directory.
 *
 * @flow
 */

/**
 * This is mirror from
 * https://github.com/facebook/react-native/blob/master/Libraries/Inspector/resolveBoxStyle.js
 *
 * Resolve a style property into it's component parts, e.g.
 *
 * resolveBoxStyle('margin', {margin: 5, marginBottom: 10})
 * ->
 * {top: 5, left: 5, right: 5, bottom: 10}
 *
 * If none are set, returns false.
 */
function resolveBoxStyle(prefix: string, style: Object): ?Object {
  var res = {};
  var subs = ['top', 'left', 'bottom', 'right'];
  var set = false;
  subs.forEach(sub => {
    res[sub] = style[prefix] || 0;
  });
  if (style[prefix]) {
    set = true;
  }
  if (style[prefix + 'Vertical']) {
    res.top = res.bottom = style[prefix + 'Vertical'];
    set = true;
  }
  if (style[prefix + 'Horizontal']) {
    res.left = res.right = style[prefix + 'Horizontal'];
    set = true;
  }
  subs.forEach(sub => {
    var val = style[prefix + capFirst(sub)];
    if (val) {
      res[sub] = val;
      set = true;
    }
  });
  if (!set) {
    return null;
  }
  return res;
}

function capFirst(text) {
  return text[0].toUpperCase() + text.slice(1);
}

module.exports = resolveBoxStyle;


Arsenal fullback Sagna: I feel back to my best

Sagna featured in Arsenal's 7-0 rout of the Indonesian Allstars on the weekend.

"I'm very happy. Last year I missed pre-season so I was struggling a bit during the season. I'm looking forward to getting back to my best - that's my aim and after that we'll see," he told arsenal.com.


Art © = IcePhoenix202 Doctor Who © BCCDoctor Whooves & Ditzy Doo © HasbroBackground © sulyo.deviantart.com/art/Everf... ~~~EDIT: I guess a layer was off so I put it back on.Well, I'm tired, I can tell that. U.UI love everything about this! I see no wrong.~~~Doctor Whooves (10th Doctor) has his Sonic Screwdriver in his ear and the TARDIS teleport/light thing is glowing-meaning it'll be taking off any moment with or without them.A dalek occupies their little time. :3~~~Layers: Probably over 70, last time I checkedTime: 6-8 hoursProgram: SAI


Bradford murders

The Bradford murders were the serial killings of three women in the city of Bradford, West Yorkshire, England in 2009 and 2010.

43-year-old Susan Rushworth disappeared on 22 June 2009, followed by 31-year-old Shelley Armitage on 26 April 2010 and 36-year-old Suzanne Blamires on 21 May of the same year. The women were all sex workers based in Bradford. Parts of Blamires's body were found in the River Aire in Shipley, near Bradford, on 25 May. Other human tissue found in the same river was later established to belong to Armitage. No remains of Rushworth have ever been found.

Stephen Shaun Griffiths, 40, was arrested on 24 May and subsequently charged with killing the three women. After being found guilty, he was sentenced to life imprisonment with a whole life order.

Conviction of Stephen Griffiths

Stephen Shaun Griffiths (born 24 December 1969 in Dewsbury, West Riding of Yorkshire) was arrested and in May 2010 he appeared in the magistrates' court giving his name as the Crossbow Cannibal.

At a crown court appearance that afternoon he was remanded in custody until his next court appearance. He made a second appearance at crown court on 7 June via a video link from Wakefield Prison where a trial date of 16 November 2010 was set.

On 21 December 2010, Griffiths was convicted of all three murders after pleading guilty. At Leeds Crown Court the same day, Mr Justice Openshaw sentenced Griffiths to life imprisonment with a whole life order, meaning he will not become eligible for parole and is likely to spend the rest of his life in prison. While in prison, Griffiths has attempted suicide on several occasions. He has also been on a 2-month hunger strike, during which time he avoided contact with other people.

Post trial statements
Griffiths' criminal history included a 3-year sentence, when aged 17, for an unprovoked knife attack on a supermarket manager. Whilst in custody he stated that he saw himself becoming a murderer, and psychiatrists warned that he fantasised about becoming a serial killer. In 1991 he was diagnosed as a "schizoid psychopath" and the following year received a two-year prison sentence for holding a knife to the throat of a girl.

In 2009, Griffiths was admitted to the University of Bradford to write a PhD in homicide studies.

Police had been watching Griffiths for two years before he killed his victims and had already seized hunting weapons. The police contacted the housing association which owns the flat in which Griffiths lived after Griffiths was observed reading books on dismemberment.  The housing association shared the police's concerns and fitted a better CCTV system in anticipation of an incident. At the time of the murders, police had no evidence for an Anti-Social Behaviour Order.

Government reaction
David Cameron, the then new Conservative prime minister, said the murders were a "terrible shock". He said the decriminalisation of offences related to prostitution should be "looked at again", but he also added that: "I don't think we should jump to conclusions on this – there are all sorts of problems that decriminalisation would bring." Later, aides close to Cameron strongly insisted he was concerned with addressing the social problems surrounding it such as encouraging agencies to work together to help women off the streets or to combat drug addiction. Cameron has also called for tougher action on kerb-crawling and drug abuse.
The debate as to whether a change in the law would protect sex workers continues.

References

Category:2009 murders in the United Kingdom
Category:2009 in England
Category:2010 murders in the United Kingdom
Category:2010 in England
Category:2000s in West Yorkshire
Category:Crime in Bradford
Category:History of Bradford
Category:Murder in West Yorkshire
Category:Serial murders in the United Kingdom
Category:Violence against sex workers in the United Kingdom
Category:Violence against women in England
Category:Incidents of violence against women
Category:Male serial killers
Category:English serial killers
Category:Female murder victims
Category:2010s in West Yorkshire


#Sat Jul 11 22:52:37 CEST 2009
eclipse.preferences.version=1
org.eclipse.jdt.core.compiler.codegen.inlineJsrBytecode=enabled
org.eclipse.jdt.core.compiler.codegen.targetPlatform=1.6
org.eclipse.jdt.core.compiler.compliance=1.6
org.eclipse.jdt.core.compiler.problem.assertIdentifier=error
org.eclipse.jdt.core.compiler.problem.enumIdentifier=error
org.eclipse.jdt.core.compiler.source=1.6


Tools released at Defcon can crack widely used PPTP encryption in under a day - lesterbuck
http://www.csoonline.com/article/712429/tools-released-at-defcon-can-crack-widely-used-pptp-encryption-in-under-a-day

======
gnyman
I wonder how the big VPN service providers are going to react to this, as far
as I know ipredator (<http://ipredator.se/>) uses only MSCAP-2.

Also, why is this news not on the top of "hacker-news", it really puts the
usefulness of HN into question if news like these are buried somewhere :-(


The long range aim of this research is to study the function of neurotransmitters in the maintenance of behavior and the mediation of the action of drugs affecting behavior. The research will focus on dopamine, norepinephrine and 5-hydroxytryptamine and their relationship to operant behavior. Feeding and drinking will also be considered as they relate to operant behavior. The neurotransmitters in the CNS will be modified by using drugs and/or neurotoxins. Behavior will be measured by using various operant techniques and the control and analysis of the data will be computer oriented. There are three major areas of interest upon which this research will focus. First, the effects of drugs acting on monoaminergic systems; second, describing interaction between behavioral, environmental and phamacological variables in affecting monoamine metabolism; and third, the behavioral, pharmacological and neurochemical aspects of tolerance to drugs affecting the monoaminergic system.


Music listening alleviates anxiety and physiological responses in patients receiving spinal anesthesia.
The aim of this study was to explore the effects of listening to music on the anxiety levels and physiological responses of surgical patients receiving spinal anesthesia. An experimental design was used in the study with an experimental group (n=50) and a control group (n=50). The experimental group received 30min of musical intervention and routine nursing care in the Post-Anesthesia Care Unit (PACU) while the control group received only routine nursing care. The study found significant differences in both anxiety and physiological indices between the two groups. The mean score of the State-Trait Anxiety Inventory (STAI) in the study group decreased from a pre-test score of 59.0 to a post-test score of 31.20 (t=28.63, p<0.001). Physiological indices such as heart rate (t=2.61, p=0.012), respiration rate (t=2.29, p=0.026), systolic blood pressure (t=2.30, p=0.026), and diastolic blood pressure (t=3.02, p=0.004) decreased significantly as well. Control group was not seeing significant changes from pre-op values. Listening to music while in the recovery room may decrease the level of anxiety in surgical patients receiving spinal anesthesia. The results of this study can serve as a reference for PACU nurses in utilizing music listening programs to achieve the goal of holistic care.


Q:

Open set generated by two equivalent norm

Suppose X is an vector space and $||.||_a$ and $||.||_b$ are two norm on it, how i can proof that ''This two norms are equivalent iff they generate same open sets."?
P.S.: Sense of question made by ''Principles of Real Analysis, C.D. Aliprantis, O. Burkinshaw, 3rd Edition, p220.".

A:

It is easy to see that equivalent norms yield the same open sets, because if $K \cdot \Vert x \Vert_a \leq \Vert x \Vert_b \leq M \Vert x \Vert_a$, you have
$$
B_r^{\Vert \cdot \Vert_a}(x_0) \subset B_{r \cdot M}^{\Vert \cdot \Vert_b}(x_0)
$$
and vice versa (show this!).
As a set $U$ is open (w.r.t. $\Vert \cdot \Vert$) iff for each $x \in U$ there is some $\varepsilon >0$ with $B_\varepsilon^{\Vert \cdot \Vert} (x) \subset U$, you should be able to show that $U$ is open w.r.t. $\Vert \cdot \Vert_a$ iff it is open w.r.t. the other norm.
For the converse, note that $B_1^{\Vert \cdot \Vert_a}(0)$ is open w.r.t. the first norm (why?), so by assumption also w.r.t. the second norm.
Thus, there is $\varepsilon > 0$ with
$$
B_\varepsilon^{\Vert \cdot \Vert_b}(0) \subset B_1^{\Vert \cdot \Vert_a}(0).
$$
This should allow you to conclude that $\Vert \cdot \Vert_a \leq \frac{1}{\varepsilon} \Vert \cdot \Vert_b$.


Engagement with China

The 2016 CDU Engagement with China Event showcased activities undertaken by the Confucius Institute; CDU’s diverse research collaboration, education and training initiatives with partner Chinese universities; Australian government funded in-country study programs for Australian students; and selected Chinese international student experiences at CDU.


It appears Osama bin Laden may not have been totally disconnected electronically.

Despite reports that he didn’t have Internet connection or mobile service, Reuters quotes high-ranking Pentagon officials saying the Navy SEALs found pornography --- and a lot of it -- at Bin Laden's compound in Abbottabad, Pakistan, consisting of “modern, electronically recorded video.”

[Updated, 4:35 p.m.] According to the report, there was no word on how the material got there or to whom it belonged, as other people also lived inside the compound with Bin Laden. The story relies on unnamed government officials who have not released any other details or other evidence to back the claims.

The report has prompted some analysts to speculate that the porn may have been brought into the compound using thumb-sized flash drives that Bin Laden allegedly used to send emails while in hiding. Or it could’ve been through the satellite television that he used to watch Al Jazeera.

Either way, it was there, according to the officials, who declined to disclose the titles of the “extensive” collection.

RELATED:

Bin Laden death is magnet for scammers on Facebook, Google

Timeline of Bin Laden raid

Photos: Death of Bin Laden

-- W.J. Hennigan

Photo: The U.S. government released five videos seized at Osama bin Laden's compound, including this image of the Al Qaeda leader watching himself on TV, with President Obama also seen. Credit: Reuters


Musings Post

Every month I send out a newsletter to subscribers with the most recent evidence and studies on specific body work topics. The newsletter may include summaries and links to studies and articles, videos that provide support information about exercises, new techniques or lectures. There are five main focuses for the newsletters and each newsletter is repeated twice a year. The six main focuses for the newsletters are: Shoulder and rotator cuff, fibromyalgia, fascia and trigger points, upper cross and neck, cupping and lymphatic drainage and business/ethics. If you would like to receive the newsletters with more complete information than is found in the excerpts, please sign up to receive the newsletter on my contact page.

PLEASE NOTE: This is the last edition of the Fibromyalgia newsletter. This newsletter will be converted to a newsletter with a focus on chronic pain conditions rather than the narrow focus of fibromyalgia.

Excerpt:

Tips & Tidbits

Patients with fibromyalgia show significantly lower levels of serum vitamin D than those of a control group.

Studies, Articles, and Resources

A study titled “A pilot study of myofascial release therapy compared to Swedish massage in Fibromyalgia” by Liptan, Mist, Wright, Arzt & Jones, published in Journal of Bodywork and Movement Therapies concluded: between-group differences in symptoms and physical function did not reach statistical significance. There were no consistent focal areas of improvement for the Swedish massage group while the MFR group reported consistent pain reductions in the neck and upper back regions. A larger randomized controlled trial is called for.

In a study in Man Ther 2015 by Yuan, Matsutani & Marques, titled “Effectiveness of different styles of massage therapy in fibromyalgia: a systematic review and meta-analysis”, the authors concluded: myofascial release had large, positive effects on pain and medium effects on anxiety and depression at the end of treatment; myofascial release also improves fatigue, stiffness and quality of life; connective tissue massage improves depression and quality of life; manual lymphatic drainage is superior to connective tissue massage regarding stiffness, depression and quality of life; Shiatsu improves pain, pressure pain threshold, fatigue, sleep and quality of life; and Swedish massage does not improve outcomes.

In a study, published in Rheumatol Int. 2017 titled “A comparison of the effects of exercises plus connective tissue massage to exercises alone in women with fibromyalgia syndrome: a randomized controlled trial” concluded: exercises with and without connective tissue massage might be effective for decreasing pain, fatigue and sleep problem whereas increasing health status and quality of life. However, exercises with CTM might be superior in improving pain, fatigue, sleep problem, and role limitations due to physical health compared to exercise alone.

A study, published in J Pain Res. 2017, titled “Caffeine as an opioid analgesic adjuvant in fibromyalgia” concluded: caffeine consumption was associated with decreased pain and symptom severity in opioid users, but not in opioid nonusers, indicating caffeine may act as an opioid adjuvant in fibromyalgia-like chronic pain patients. This data suggest that caffeine consumption concomitant with opioid analgesics could provide therapeutic benefits not seen with opioids or caffeine alone.

A study published in Complement Ther Clin Prati in Aug 2017, titled “Effects of whole-body vibration therapy in pain, function and depression of the patients with fibromyalgia” concluded: Whole body vibration therapy is found to be effective in reducing symptoms of fibromyalgia.

A study published in Clin Biomech titled “Effects of a 16-week hydrotherapy program on three-dimensional scapular motion and pain of women with fibromyalgia: a single-arm study” concluded: Hydrotherapy was effective to improve quality of life, pain intensity and fibromyalgia impact on women. However, scapular kinematics did not change after the period of treatment. Although symptoms improved, the lack of changes in scapular kinematics may indicate these women have an adaptive movement pattern due to their chronic painful condition.


Q:

Detect device screen size in craft cms

How can I get the screen size in craft cms? I mean the device width in px, so for example I can get a static map image with the exact size to fit the device screen

A:

I think you are going to struggle with this in Craft, you would need to do it through Javascript.
Craft runs off PHP which is a server side scripting language, you need a client side scripting language.
Here is a good question which should help you with this: Get the size of the screen, current web page and browser window


package sum_of_two_integers_371

import (
	"github.com/stretchr/testify/assert"
	"testing"
)

func Test_getSum(t *testing.T) {
	type args struct {
		a int
		b int
	}
	tests := []struct {
		name string
		args args
		want int
	}{
		{
			name: "sum of two integers",
			args: args{
				a: 2,
				b: 3,
			},
			want: 5,
		},
		{
			name: "sum of two integers",
			args: args{
				a: 1,
				b: 2,
			},
			want: 3,
		},
		{
			name: "sum of two integers",
			args: args{
				a: -2,
				b: 3,
			},
			want: 1,
		},
		{
			name: "sum of two integers",
			args: args{
				a: -2,
				b: -3,
			},
			want: -5,
		},
	}
	for _, tt := range tests {
		t.Run(tt.name, func(t *testing.T) {
			assert.Equal(t, tt.want, getSum(tt.args.a, tt.args.b))
		})
	}
}


Infective dermatitis associated with HTLV-1 mimics common eczemas in children and may be a prelude to severe systemic diseases.
Infective dermatitis associated with human T-cell lymphotropic virus type 1 (HTLV-1) (IDH) is a chronic dermatitis that has been observed in a variable proportion of HTLV-1-infected children. IDH may serve as an early clinical marker for HTLV-1 infection and an indicator of increased risk for developing other HTLV-1-associated conditions. Factors that lead only some infected children to develop IDH are poorly understood. The variable clinical presentation of IDH, in particular its chronicity, the morphology and distribution of the lesions, and its clinical resemblance to other cutaneous inflammatory conditions, make it necessary to distinguish it from other common dermatoses.


Does your Child Hate Tags and Jeans and…

If you scour the internet for seamless socks and buy multiple pairs of the same exact pants because your child will actually wear them, you are not alone. There are many of us out there, dealing with sensitive children who give us a long list of criteria for what they are willing to wear.

So what’s the deal? Since when did seamless socks become a thing?

Actually, this is not a new problem, we all have various degrees of sensitivities. It was even named a thing by Jean Ayres in the 1970s. But it wasn’t until the last decade or so, that we’ve begun to understand the depth and severity these sensitivities can cause.

These sensory issues can range from a mild nuisance to a debilitating Sensory Processing Disorder (SPD). SPD can go way beyond just clothing sensitivity and can impact all areas of a child’s sensory world.

Ever since I was a kid I hated collars and clothes that restrained me. My feet needed to “breathe” often. I avoided jeans like the plague. I got car sick if I didn’t keep my eyes on the road and you’d better hand me a barf bag if I went anywhere near an amusement ride. Little did I know, those are all signs of sensory issues.

Fast forward a zillion years (I am really old). Enter my first child. I was so excited to have a girl! I wanted to dress her up and do her hair. However, I quickly learned I would be lucky to get her dressed at all. And her hair, forget about it. Cute pigtails were replaced with a short haircut to minimize the disheveled look of a head that refused to be brushed.

Seamless socks, cotton pants and crocs became my daughter’s life. Buying shoes was a major battle. Some were too tight. Some were too loose. I would sit there on the floor of the store in a sea of rejected shoes overwhelmed and exhausted. “Forget it,” I would say. “I have had enough for today. We’ll try again next week.”

It took me many years to find my beat with my sensitive girl. It took her many years to get used to her skin.

I want to spare you the struggle. Spare you the battles I should have never had – and never won. Tell you what I tell parents who come into my therapy practice, looking worn out and baffled by their sensitive kids. Their kids who demand seamless socks. Their kids who demand to wear shorts in the winter or pants in the summer. Kids who look like they are literally tortured by their own skin.

Here are some words of wisdom from someone who has been where you are…

Your Child isn’t trying to be difficult when they ask for seamless socks & cotton pants.

Your child doesn’t want to itch and pull at their clothes. They don’t want to feel like they are wearing sandpaper disguised as a shirt. Their skin is literally more sensitive than yours. It’s not in their head, it’s in their skin.

Once you recognize this, your home will be much more peaceful.

Don’t fight with them, join them in the fight to find comfy clothes.

Give up your concept of fashion.

You know those cute studded jeans with the lace on the bottom. Forget about it. You know that adorable dress made of pink chiffon, it’s not going to happen. You need to grieve any preconceived notion of how you thought your child would dress. You need to release any expectation on how you want your child to look.

This was a hard one for me. I had to swallow my pride and not care how my child looked. I knew other people wouldn’t understand and I had to learn to not care. That was a good life lesson.

Buy in bulk.

Having a child with sensory issues can get costly. What felt good in the store, no longer feels good at home. Or worse, it only starts to feel bad after the tags are off and its been worn once or twice.

I watched money go down the drain. It was hard not to get mad.

One thing I learned early on was to buy in bulk. When my daughter found a comfy pair of pants, I bought them in every color. When she found a shirt she would actually wear, I bought several of them.

Wait a good week or two before you buy in bulk, just to make sure it passes the skin test several times.

Pay attention to brands.

You might not think there is a big difference between Fruit of the Looms and Hane’s underwear or socks, but trust me your kid does. Pay attention to what brands you buy. I learned to save the packaging of any socks and underwear I bought, so I could buy the exact brand again.

Sensitive kids get used to the way a particular brand feels and they have a hard time adjusting to a new brand. This is not your child being difficult, it is their skin.

Let your child battle themselves.

Kids with sensory issues get just as frustrated as you. They don’t always know how to manage this frustration and they often take it out on their parents.

Get out of the line of fire! There is no need for you to interject yourself in their clothing battle. That is between them and their skin.

Have your child pick out their own clothes. If they are really young, make two bins. One bin of shirts and one bin of bottoms. Have all the shirts and bottoms match. That way you can let them dress themselves, but they’ll at least match!

If your child has a hard time getting dressed in the morning, have them shower and get dressed the night before. I know that might sound gross, but sometimes it takes sensitive skin some time to get used to the clothes. By getting dressed the night before, your child won’t have to go through the “it doesn’t feel right” stage in the morning.

Explain sensory issues to your child.

Education goes a long way. Once my daughter learned why her clothes felt bad on her skin, she was able to adapt. She paid attention to what felt right and she learned to shop by touch, not by sight. As a teen, she now knows what works and what doesn’t for her skin. She also knows that she has sensory issues and that it isn’t her fault.

Educate yourself.

Sensory issues don’t go away, kids and parents just learn to adapt. The best thing you can do as a parent is to educate yourself on how sensory processing issues work and what you can do to help your child.

Do you have a child with these sensory issues? What’s your best tip for parents out there? Do you know someone who frequently shops for seamless socks and soft clothes? Share this article with them!

Other Articles on Sensory Processing:

This site is for informational purposes only and should not be used to replace the guidance of a qualified professional. This page may contain affiliate links. I receive a small commission for items purchased. I would never endorse any product I didn't recommend. Click here for my full disclosure statement.

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Page 2: Greyhounds for Sale in West Palm Beach, Florida

Basic Information: Kennel Name: Chester, Color: White and Brindle, DOB: 06/29/09 Chester is a recent return to the kennel through no fault of his own. His family was unable to keep him because Mom twisted her knee and could not leash walk him any longer and... see more at Petfinder.com. See more Greyhounds in Miami

Basic Information: Kennel Name: Chester, Color: White and Brindle, DOB: 06/29/09 Chester is a recent return to the kennel through no faul...

Basic Info: Kennel Name: Buddy, Color: Black, DOB: 11/22/11, Cat Test: no Buddy is a neat dog and learns the routine and rules quickly. He is very attractive and seems to get along with everyone but is content with a soft cushion and a toy. He s... see more at Petfinder.com. See more Greyhounds in Miami

Ramone is very playful boy. Good with all animals and children. He loves to play fetch.
He is an active boy extra sweet personality. Very verbal and social.... see more at Petfinder.com. See more Great Danes, Greyhounds in West Palm Beach

Ramone is very playful boy. Good with all animals and children. He loves to play fetch.
He is an active boy extra sweet personality. Very...

2/17/15 MEET SIERRA. Sierra came to us from a high kill shelter with her babies. She was a cute mother and all her babies have been adopted. Sierra unfortunately had heart worms when we took her in. We have spayed her and she has just finished the heart worm treatment program. Sierra is potty trained. We did a DNA test on her and it said she is a Boxer/Greyhound mixture. She is a adorable dog who loves just hanging around the house lazing on the couch. She sleeps in bed with me and does not move all night! She gets along well with the other dogs in the house but I do not know about cats. Sierra is about 7-9yrs old. She has had a broken jaw at 1 point in time that was not attended to and half of her bottom teeth are missing. We believe she was used as a hunting hog dog and not cared for. She has scars and tags all over her body but all her hair has grown back! YAY! She came to us with hardly any hair. She will need a home that loves her dearly and can show her lots of love as she has lots to give back!. See more Boxers, Greyhounds in West Palm Beach

2/17/15 MEET SIERRA. Sierra came to us from a high kill shelter with her babies. She was a cute mother and all her babies have been adopt...

Basic Information: Kennel Name: Kingsley, Color: Red Brindle, DOB: 07/18/13 Kingsley is almost 2 yrs young, and a attractive red brindle boy. He comes from a adorable bloodline of greyhound racers but this little boy is a very, very scardy cat. We named h... see more at Petfinder.com. See more Greyhounds in Miami

Lady is a 9yr old, 65lb girl and Sport is a nine year old, 72 lb boy who have been in a home together since 2009 but due to the unfortunate passing of their owner are now looking for a new home. They're both very adorable dogs that will need to be adopted together. Their racing names were Craigie O Mara and Joker Dodgem.. See more Greyhounds in West Palm Beach

Lady is a 9yr old, 65lb girl and Sport is a nine year old, 72 lb boy who have been in a home together since 2009 but due to the unfortuna...

2/17/15 MEET SIERRA. Sierra came to us from a high kill shelter with her babies. She was a sweet mother and all her babies have been adopted. Sierra unfortunately had heart worms when we took her in. We have spayed her and she has just finished th... see more at Petfinder.com. See more Boxers, Greyhounds in West Palm Beach

2/17/15 MEET SIERRA. Sierra came to us from a high kill shelter with her babies. She was a sweet mother and all her babies have been adop...

Lady and Sport are both 9 yrs old and have been in a home together since 2009 but due to the unfortunate passing of their owner are now looking for a new home. They're both extra sweet dogs that will need to be adopted together. Their racing name... see more at Petfinder.com. See more Greyhounds in West Palm Beach

Lady and Sport are both 9 yrs old and have been in a home together since 2009 but due to the unfortunate passing of their owner are now l...


[Brown tumor in hyperparathyroidism secondary to chronic renal failure].
Brown tumor (BT) is an uncommon condition that represents the terminal stage of the cystic osteitis fibrosa and have been increasingly reported in hyperparathyroidism secondary to renal failure, due to the increase of survival in patient with hemodialysis. The fine needle aspiration diagnosis is of great importance in the recognition of the BT, although it can be difficult to distinguish it of lesions as the aneurysmal bone cyst and giant-cell tumor. We describe the case of 20-year-old female with chronic renal failure undergoing hemodialysis during six years. Both x-rays and computer tomography revealed a tumor in head of right humerus and lytic images in scapula of the same side, clavicles and ribs. The patient was subjected to a fine needle aspiration biopsy of the tumor of humerus head and the sample was processed with the habitual technique of inclusion in paraffin and stained with hematoxilina and eosina. Histological preparations showed several multinucleate giant cells and spindly or fibrillary cells, feature that was pointed out as compatible, in a context of secondary hyperparathyroidism to chronic renal failure, with a BT. We consider that the radiological and tomographyc finds, besides the history of chronic renal failure with a long history of hemodialysis, were enough to link, with great approach, the histopathology with the diagnosis of BT.


Q:

directional derivative problem

for a point M(4,1) and a function $z  = x y^2 - (x^2/y^3)$ I was tasked with finding a directional derivative in the direction which creates a 30 degree angle with the $x$ axis....I find it a little hard to imagine and would like to get help on how this might be done..

A:

The directional derivative of a scalar function
$f(\mathbf{x}) = f(x_1, x_2, \ldots, x_n)$
along a vector
$\mathbf{v}$ is, by definition
$$\nabla_{\mathbf{v}}{f}(\mathbf{x}) = \lim_{h \rightarrow 0}{\frac{f(\mathbf{x} + h\mathbf{v}) - f(\mathbf{x})}{h}}\hbox{.}$$
In case when $\nabla{f}(\mathbf{x})$ exists, $\nabla_{\mathbf{v}}{f}(\mathbf{x}) = \nabla f(\mathbf{x}) \cdot \mathbf{v}$ if $|\mathbf{v}|=1$
where the $\nabla$ denotes the gradient and $\cdot$ is the dot product.
So one just takes the gradient (it exists in most cases); in the OP
$$\hbox{grad}\,z = \left(\frac{\partial}{\partial x}(x∗y^2−(x^2/y^3));
\frac{\partial}{\partial y}(x∗y^2−(x^2/y^3))\right)=\left(y^2-2x/y^3;2xy+3x^2/y^4\right),$$
takes the vector of norm $1$ pointing in given direction and multiplies them.
Substituting concrete variables, if necessary.
The result in the OP would be $(\hbox{grad}\, z).(\frac{\sqrt{3}}{2};\frac{1}{2})$ , the rest's up to you.


Sattam bin Abdulaziz Al Saud

Sattam bin Abdulaziz (21 January 1941 – 12 February 2013) was one of the senior members of the House of Saud and the 12th governor of the Riyadh Province.

Early life and education
Prince Sattam was born in Riyadh on 21 January 1941. He was the 30th son of King Abdulaziz. His mother was Mudhi Al Sudairi. He was the youngest and last surviving member of all of his full siblings - Prince Majid, Princess Sultana, and Princess Haya.

Sattam bin Abdulaziz began his early study in the Princes' School school in Riyadh and later joined Al Anjaal institute. He received a bachelor's degree in business administration from the University of San Diego, graduating in 1965. He received an honorary doctorate from the same university on 25 May 1975.

Career
Sattam bin Abdulaziz was the former deputy governor of Riyadh from 1979 to 2011. Prince Mohammad bin Saad succeeded him in the post. On 5 November 2011, Prince Sattam was appointed governor of Riyadh Province. He was the 12th governor of Riyadh and replaced Prince Salman, who was appointed defense minister.

Activities
In March 2012, Sattam bin Abdulaziz stated that single men would not be prevented from visiting malls in Riyadh on evenings and weekends. Previously, they were only allowed into malls at lunch time on weekdays.

Other positions
Prince Sattam was a member of the following committees: "Chairman of insolvent prisoners release committee; Deputy chairman of the executive committee of Saudization; Deputy chairman of the executive association of developing Riyadh; Deputy chairman of the board of directors of water and sanitation association at Riyadh Province; Deputy chairman of the board of directors of Al-Berr association at Riyadh; Deputy chairman of the committee of prince Salman project for charity housing; Deputy chairman of Ibn Baz charity for helping youth to marry; Deputy chairman of the orphans care association board at Riyadh region; Chairman of the local committee for gathering donations for Kosovo and Chechnya Muslims at Riyadh region; Deputy chairman of the civil defense committee; Honorary deputy chairman of the patients’ friends committee at Riyadh region; Deputy chairman of the renal failure patients care association at Riyadh region."

Awards
Prince Sattam was a recipient of the King Abdulaziz cordon from the first class which is considered the highest order in the Kingdom of Saudi Arabia.

Personal life
Sattam bin Abdulaziz was married to Sheikha bint Abdullah bin Abdul Rahman. His children are Hala, Abdulaziz, Najla and Faisal. One of his daughters, Najla, is married to Abdulaziz bin Majid. Prince Sattam donated his organs, being the first Saudi royal in this regard.

Death and funeral
On 12 February 2013, Prince Sattam died at the age of 72 following a lengthy illness in Riyadh. A funeral prayer was performed for him at Imam Turki bin Abdullah Mosque in Riyadh on 13 February 2013. The prayer, led by Sheikh Abdulaziz bin Abdullah Al al Shiekh, was also attended by King Abdullah and other senior princes and officials. Then his body was taken to Jeddah and was buried at the Al Adl cemetery in Mecca as per his will.

Ancestry

References

Category:1941 births
Category:2013 deaths
Category:University of San Diego alumni
Category:Governors of provinces in Saudi Arabia
Category:People from Riyadh Province
Category:Burials at al-Adl cemetery
Category:Recipients of the Order of Abdulaziz al Saud
Category:Sons of Ibn Saud


Tuesday, February 22, 2011

We must be in the middle of Sweeps Month or something, because I can't seem to turn on my TV of a Sunday evening without stumbling on some national broadcast of a highly anticipated annual event. First there was the Golden Globes all those weeks back. Then the Super Bowl. Then the Grammys. And this most recent Sunday, the NBA All-Star Game. And of course we all know what highly-politicized, celebration of the year's best in cinema happens next Sunday…

Living in Los Angeles, it was hard to escape the buzz of All-Star Weekend, the festivities of which took place at Staples Center, the home stadium of All-Star Game MVP Kobe Bryant (and fellow All-Stars Pau Gasol and Blake Griffin). The Staples Center has been playing double and triple duty later, as it was recently home to the aforementioned Grammys in addition to its role as home for the Lakers, Clippers, and Kings, as well as a happening venue for concerts and special events.

Events at the Staples Center are fun. I've been to a single Laker game and a single WWE Event there, and have enjoyed my time thoroughly. The LA Live center surrounding it is shiny and metallic and perpetually seems to have the mall equivalent of new car smell. And despite the havoc wrought by these events on the already legendary LA traffic, it's nice to know that there is never a dearth of culture and excitement in this, the entertainment capitol of the world.

Fortunately, the events downtown didn't impact the traffic to LAX, so I was able to make my flight for my surprise, late-notice business trip without any hassle. Unfortunately, said trip is taking up the majority of my time and energy right now, so I'll be back next week in full technicolor and with a full-length post.


To determine the moisture content in a sample, the sample is dried and the weight of the sample is measured before and after the drying process. Due to the extensive amount of work involved, this method is very expensive as well as error-prone.
In some cases, the weight loss can also be measured during the drying process. In a given sample, the decrease in weight is a function of the temperature, the length of the drying time, and the conditions in the test compartment, and it conforms to a curve representing the sample weight as a function of the elapsed drying time which asymptotically approaches the dry weight of the sample. The curve for the given sample is determined by comparative experiments and can be expressed mathematically through an approximation formula. A measuring instrument for gravimetric moisture determination which is appropriately equipped with available electronic technology can compute the moisture content of a sample based on the measured parameters of the aforementioned curve and based on the length of the drying time and indicate the result on a display unit. With this method, the substance to be dried does no longer need to be totally desiccated; it is sufficient to determine the coordinates of two measurement points in the weight-versus-time diagram.
As has already been mentioned at the beginning, the weight change of a sample is substantially a function of the temperature, the length of the drying time, and the conditions in the test compartment. Especially the stringent requirements imposed on the test compartment and its design features are setting a limit to the accuracy of the commercially available instruments.
The term “test compartment” in the present context means a space which is enclosed by the housing of the measuring instrument and which can be opened in order to insert or remove a sample. Also arranged inside the test compartment are a sample receiver and a means to heat the sample. The sample receiver is connected to a gravimetric measuring instrument.
Normally, the sample is spread in a thin layer onto a flat sample receiver, for example a sample tray. The tray is preferably arranged in the measuring instrument for gravimetric moisture determination in such a way that the sample-carrying area is horizontally leveled, so that samples of low viscosity cannot collect at the lowest point (relative to the direction of the load) of the sample tray.
As a means for heating the sample, a variety of radiation sources are used, such as heat radiators, microwave generators, halogen- and quartz lamps. A gravimetric moisture-determination instrument of the aforementioned type is disclosed in commonly-owned U.S. Pat. No. 5,485,684, issued 23 Jan. 1996 to Philipp, et al. In this instrument, the sample substance is put on the weighing pan while the latter is outside of the gravimetric moisture-determination instrument. To do this, the balance is pulled out of the housing of the measuring instrument on a sliding carrier like a drawer. For a radiation source, a ring-shaped halogen lamp is used which is located above the sample receiver when the instrument is in its operating condition.
As was found in experiments, the type and the design configuration of the radiation source being used are among the primary causes for inaccurate measurement results in existing gravimetric moisture-determination instruments. For example, radiators with perforations or radiators whose radiation originates substantially from a point or a line can cause a non-uniform irradiation of the sample with the result that the energy density in individual spots of the sample can be so high as to cause in some places a thermal breakdown of the sample.
If the radiator spans over the sample in a spread-out and largely flat configuration, it is possible that a moisture-saturated gas cushion will form between the sample and the radiator and remain in place, whereby a further escape of moisture from he sample is prevented. Such an obstruction to the drying process could have a significant effect on the drying time, wherein in particular the temperature-related random atmospheric convection between the radiator and the sample enter into the measuring result.
The errors in the drying time that are caused by the obstruction in the drying process, and/or the measurement errors in the sample weight values due to thermal decomposition impose a limit on the accuracy that can be obtained in an analysis with the aforementioned mathematical model. As an alternative to using the mathematical model, one can use the known method in which all of the moisture—to the extent that this is possible—has to be driven out of the sample. However, this requires a very long drying time, which increases the risk that a thermal decomposition or oxidation of the sample will occur as a result of the long, sustained exposure to the heat radiation of the radiators.
For the reasons that have just been explained, it is hardly possible to determine an absolute value for the moisture content with a gravimetric moisture-determination instrument. For a more accurate determination of the moisture content of a substance or for the calibration of dryers, the known Karl Fischer titration method is therefore still in use. This method is very labor-intensive, prone to user errors, and expensive.
It is therefore the object of the present invention to provide a gravimetric moisture-determination instrument with a radiator that has an improved distribution of the radiation over the sample. Furthermore, the escape of moisture from the sample should not be compromised as a result of the improved distribution of the radiation.


It’s good to see government agencies, departments and offices come up with innovative ideas to stretch taxpayer dollars as far as possible.

That’s why we were pleased to read about two separate initiatives undertaken recently by Laketran and the Painesville Township Fire Department.

At Laketran, an idea that will save money and potentially produce revenue arose after the transit agency began having difficulty finding vendors to perform alignments on its 35-foot transit buses and 40-foot commuter coaches.

“Our local vendor here in Lake County told us they did not want to continue to perform the service,” said Keith Bare, Laketran’s director of maintenance, on Nov. 27 during a presentation to the Laketran Board of Trustees. “We’re currently driving our buses to the west side of Cleveland, but the travel time is cost-prohibitive.”

As Bare considered alternatives, he came up with an idea that led back to Laketran’s own maintenance garage.

He suggested Laketran bring alignment service in-house with potential to sell the services through governmental agency contracts.

“We believe there are other governmental agencies, like the county or local school districts, that may be having the same difficulties,” said Laketran General Manager Ben Capelle. “Once our maintenance department is trained and we have a general idea of how much time the alignment will take, we plan to offer alignment services to governmental agencies within Lake County.

“The alignment machine will pay for itself in just four years, but selling alignment service to other government agencies that operate heavy-duty vehicles could at some point generate revenue for the agency,” he added.

Laketran’s board approved the purchase of the American-made Hunter Engineering three-axle alignment machine from New York-based, Mohawk Resources, Ltd., at a state contract price of $43,510.75.

New technology from Hunter Engineering provides three-axle wheel alignments with software that supports specialized truck, trailer and bus alignments to meet the needs of Laketran’s diversified bus fleet, and ability to service other customized government vehicles, the release stated.

So with a state-of-the art alignment machine and a staff of highly skilled mechanics, Laketran has positioned itself to not only save on maintenance expenses for its own bus fleet, but also to work with other governmental agencies who need similar work done on their buses or trucks.

The concept of regionalism — government entities from different nearby communities sharing services, personnel or programs to save money for all parties involved — has become quite popular in recent years. So give Laketran credit for seeing how doing alignment services in-house was a smart idea.

Meanwhile, the Painesville Township Fire Department recently came up with and carried out a cost-saving proposal of its own that deserves some extra attention.

The department recently welcomed two new emergency vehicles to its Station No. 3.

The rescue squad, which was recently placed in service, is a unique blend of a new engine and the “box” of the old unit.

Painesville Township Fire Chief Frank Huffman said the former 2006 Ford 6-Liter Diesel Squad had multiple engine problems and became costly to repair.

“It was basically a remodel,” Huffman said. “We bought a brand new chassis (2017 V10 gasoline) and put the old box on the new frame. We did it all under $50,000.”

Firefighter Shawn Forster, who served as the lead mechanic, said it was truly team effort.

“The whole department really helped out on this,” he said.

The firefighters did all the labor in about six weeks, which was a major cost savings.

The price for a new Squad is estimated to be $205,000, but the department was able to complete the entire job for just around $40,000, saving the township and residents over $160,000, according to the Painesville Township Fire Department’s Facebook post.

Talk about some impressive cost savings.

We commend the Painesville Township Fire Department for displaying its resourcefulness, mechanical expertise and ambition in completing this project.

It’s always a challenge for government entities to find ways to reduce costs without sacrificing the quality of services provided to the residents they serve. But Laketran and the Painesville Township Fire Department showed how it can be done, with projects such as ones highlighted above.


Extrusion of actin-positive strands from Hep-2 and Int 407 cells caused by outer membrane preparations of enteropathogenic Escherichia coil and specific attachment of wild type bacteria to the strands.
Enteropathogenic Escherichia coli (EPEC) causes persistent infantile diarrhoea. This nontoxigenic E. coli exhibits a complicated pathogenic mechanism in which its outer membrane proteins and type III secretory proteins damage intestinal epithelium and cause diarrhoea. In accordance with this, our previous study using HEp-2 cells demonstrated cytopathic effects caused by cell-free outer membrane preparations of EPEC. In this study, we report the extrusion of actin-positive strands from HEp-2 and Int 407 cells when treated with outer membrane preparations. An interesting observation of this work, perhaps relevant to the characteristic localized three-dimensional colony formation of EPEC, is the attachment of a wild type EPEC strain to these actin-positive strands.


package com.dslplatform.json.generated.types.Decimal;

import com.dslplatform.json.generated.types.StaticJson;
import com.dslplatform.json.generated.ocd.javaasserts.DecimalAsserts;

import java.io.IOException;

public class OneArrayOfOneDecimalsDefaultValueTurtle {
	private static StaticJson.JsonSerialization jsonSerialization;

	@org.junit.BeforeClass
	public static void initializeJsonSerialization() throws IOException {
		jsonSerialization = StaticJson.getSerialization();
	}

	@org.junit.Test
	public void testDefaultValueEquality() throws IOException {
		final java.math.BigDecimal[] defaultValue = new java.math.BigDecimal[0];
		final StaticJson.Bytes defaultValueJsonSerialized = jsonSerialization.serialize(defaultValue);
		final java.math.BigDecimal[] defaultValueJsonDeserialized = jsonSerialization.deserialize(java.math.BigDecimal[].class, defaultValueJsonSerialized.content, defaultValueJsonSerialized.length);
		DecimalAsserts.assertOneArrayOfOneEquals(defaultValue, defaultValueJsonDeserialized);
	}

	@org.junit.Test
	public void testBorderValue1Equality() throws IOException {
		final java.math.BigDecimal[] borderValue1 = new java.math.BigDecimal[] { java.math.BigDecimal.ZERO };
		final StaticJson.Bytes borderValue1JsonSerialized = jsonSerialization.serialize(borderValue1);
		final java.math.BigDecimal[] borderValue1JsonDeserialized = jsonSerialization.deserialize(java.math.BigDecimal[].class, borderValue1JsonSerialized.content, borderValue1JsonSerialized.length);
		DecimalAsserts.assertOneArrayOfOneEquals(borderValue1, borderValue1JsonDeserialized);
	}

	@org.junit.Test
	public void testBorderValue2Equality() throws IOException {
		final java.math.BigDecimal[] borderValue2 = new java.math.BigDecimal[] { new java.math.BigDecimal("1E28") };
		final StaticJson.Bytes borderValue2JsonSerialized = jsonSerialization.serialize(borderValue2);
		final java.math.BigDecimal[] borderValue2JsonDeserialized = jsonSerialization.deserialize(java.math.BigDecimal[].class, borderValue2JsonSerialized.content, borderValue2JsonSerialized.length);
		DecimalAsserts.assertOneArrayOfOneEquals(borderValue2, borderValue2JsonDeserialized);
	}

	@org.junit.Test
	public void testBorderValue3Equality() throws IOException {
		final java.math.BigDecimal[] borderValue3 = new java.math.BigDecimal[] { java.math.BigDecimal.ZERO, java.math.BigDecimal.ONE, new java.math.BigDecimal("3.1415926535897932384626433832795028841971693993751058209749445923078164062862089986280348253421170679").setScale(28, java.math.BigDecimal.ROUND_HALF_UP), new java.math.BigDecimal("-1E-28"), new java.math.BigDecimal("1E28") };
		final StaticJson.Bytes borderValue3JsonSerialized = jsonSerialization.serialize(borderValue3);
		final java.math.BigDecimal[] borderValue3JsonDeserialized = jsonSerialization.deserialize(java.math.BigDecimal[].class, borderValue3JsonSerialized.content, borderValue3JsonSerialized.length);
		DecimalAsserts.assertOneArrayOfOneEquals(borderValue3, borderValue3JsonDeserialized);
	}
}