Patients with and without PAD had similar rates of stroke or systemic embolism [ HR : 1.04 , 95 % CI ( 0.72 , 1.50 ) , P = 0.84 ] and major or non-major clinically relevant ( NMCR ) bleeding [ HR : 1.11 , 95 % CI ( 0.96 , 1.28 ) , P = 0.17 ] , respectively .