Measurements were taken after each crossover arm including BP ( peripheral and central ) , adipokines ( inflammation markers and adiponectin ) , volume markers ( extracellular-to-intracellular [ E/I ] fluid ratio ; N-terminal pro-brain natriuretic peptide [ NT-proBNP ] ) , kidney function ( estimated Glomerular Filtration Rate [ eGFR ] ) and proteinuria ( urine protein-creatinine ratio [ PCR ] and albumin-creatinine ratio [ ACR ] ) .