Positive trends were found for parent-reported time at moderate-to-vigorous intensity ( between-group change ratio = 2.2 , 95 % CI 1.1 to 4.4 ) and GMFM-66 ( mean between-group difference = 2.8 points , 95 % CI 0.2 to 5.4 ) at 6 months , but not at 12 months .