Left ventricular hypertrophy ( adjusted hazard ratio , 1.52 ; 95 % confidence interval , 1.16-2 .00 ) , elevated left ventricular filling pressure ( E/E ' ; adjusted hazard ratio 1.05 per 1 integer increase ; 95 % confidence interval , 1.02-1 .07 ) , and higher pulmonary artery pressure assessed by the tricuspid regurgitation velocity ( hazard ratio , 1.23 per 0.5 m/s increase ; 95 % confidence interval , 1.02-1 .49 ) were associated with the composite outcome and heart failure hospitalization alone after adjusting for clinical and laboratory variables .