Data from 11,404 patients with chronic obstructive pulmonary disease ( COPD ) were pooled from 14 clinical studies of QVA149 , indacaterol and glycopyrronium of 3 month 's duration with at least two of the treatment groups : QVA149 110/50g , glycopyrronium 50g , indacaterol 150g , placebo or tiotropium 18g .