In this prospective , double-blind , parallel-group clinical trial , 97 consecutive subjects with MOH were randomized ( simple randomization using computer-generated numbers ) for treatment with either 400mg/day celecoxib ( for the first 5 days then decreased at a rate of 100mg every 5 days ) or prednisone 75 mg/day orally ( for the first 5 days then tapered off every 5 days ) .