This was a 3-month , multicenter , randomized , open-label study in 335 patients aged 45 years with a clinical diagnosis of BPH/LUTS by medical history and clinical examination , a total International Prostatic Symptom Score ( IPSS ) 8 points , a maximum flow rate > 5 mL/sec and 15 mL/sec , and a voided volume 120 mL .