The following indicators were recorded and compared between the two groups before and 4 and 7 days after treatments : CD4 + , CD8 + , CD4 + / CD8 + , monocytes CD14 + / human leukocyte antigen-DR ( HLA-DR ) , score of acute physiology and chronic health evaluation II ( APACHE II ) , heart rate , white blood cells , body temperature , respiration rate , and MODS ( 7 d after treatment only ) .