Multivariate analyses identified five factors that were significantly associated in predicting SNR ( odds ratio [ OR ] > 1 indicated higher chances for being SNR ) : previous surgical procedure for CD ( OR 9.8 , p = 0.013 ) , previous BoNT-A related severe adverse event ( AE ) ( OR 5.6 p = 0.027 ) , physical therapy ( OR 4.6 , p = 0.028 ) , neuroleptic use ( OR 3.3 , p = 0.019 ) and average BoNT-A dose ( OR 2.7 , p = 0.010 ) .