The incidences of nausea , vomiting and nephrotoxicity were significantly lower in the NDP group than in the DDP group ( 17.6 % vs 50.0 % , P = 0.031 ; 11.8 % vs 47.1 % , P = 0.016 ; 8.8 % vs 38.2 % , P = 0.039 ) .