MIS-RDAVR was associated with significantly reduced aortic cross-clamp times compared with FS-AVR ( 41.3 20.3 vs 54.0 20.3 minutes , p < 0.001 ) , although cardiopulmonary bypass times were similar ( 68.8 29.0 vs 74.4 28.4 minutes , p = 0.21 ) .