Median duration of response ( partial response or better ) was 1314 months ( 95 % CI 1176-1492 ) in the panobinostat group and 1087 months ( 923-1176 ) in the placebo group , and median time to response ( partial response or better ) was 151 months ( 141-164 ) in the panobinostat group and 200 months ( 161-279 ) in the placebo group .