The objective response rate ( ORR ) was 23 % ( 10/43 ) and 19 % ( 8/43 ) ( ( 2 ) = 0.281 , P = 0.596 ) , the disease control rate ( DCR ) was 79 % ( 34/43 ) and 77 % ( 33/43 ) ( ( 2 ) = 0.068 , P = 0.795 ) , and the median overall survival ( OS ) was 8.3 months and 7.5 months ( ( 2 ) = 0.756 , P = 0.385 ) , respectively ; the differences being not significant .