HEx decreased 24-hour systolic ( from 13723 to 12012 mmHg , p = 0.001 ) and diastolic BPs ( from 8113 to 7210 mmHg , p = 0.009 ) ; daytime systolic ( from 14124 to 12013 mmHg , p < 0.0001 ) and diastolic BPs ( from 8414 to 7311 mmHg , p = 0.003 ) ; and nighttime systolic ( from 12922 to 11412 mmHg , p = 0.006 ) and diastolic BPs ( from 7411 to 6610 mmHg , p < 0.0001 ) .