Nutrikinetic analysis using population-based modeling revealed the order of appearance of five genistein phase II metabolites in plasma : ( 1 ) genistein-4 ' ,7 - diglucuronide , ( 2 ) genistein-7-sulfate , ( 3 ) genistein-4 ' - sulfate-7-glucuronide , ( 4 ) genistein-4 ' - glucuronide , and ( 5 ) genistein-7-glucuronide , independent of the food matrix .