Among eyes with detailed evaluation of SHRM at weeks 56 ( n = 76 ) and 104 ( n = 66 ) , mean VA letter score was 73.5 ( standard error [ SE ] , 2.8 ) , 73.1 ( SE , 3.4 ) , 65.3 ( SE , 3.5 ) , and 63.9 ( SE , 3.7 ) when SHRM was absent , present outside the central 1 mm ( 2 ) , present within the central 1 mm ( 2 ) but not the foveal center , or present at the foveal center ( P = 0.02 ) , respectively .