Factors independently associated with a larger decrease in the sCD14 level included random assignment to receive EVG/c/FTC / TDF , higher baseline sCD14 level , and larger decreases in hsCRP and sCD163 levels ; factors associated with a larger Lp-PLA2 decrease included higher baseline Lp-PLA2 and IL-6 levels , smaller increases in total cholesterol and triglycerides levels , a larger decrease in the sCD14 level , and a smaller decrease in the sCD163 level .