The patients ' heart rate ( HR ) and mean artery pressure ( MAP ) were recorded before anesthesia ( T0 ) , before intubation ( T1 ) , immediately after intubation ( T2 ) , at 2 min before pneumoperitoneum ( T3 ) , 2 min after pneumoperitoneum ( T4 ) , at the end of the surgery ( T5 ) and extubation ( T6 ) .