Between 2 weeks and 18 months after LPI , a significant decrease in angle width was observed over time in treated eyes ( P < 0.001 for all variables ) , although the change over the first 5.5 months was not statistically significant for angle width measured under gonioscopy ( P = 0.18 ) , AOD250 ( P = 0.167 ) and ARA ( P = 0.83 ) .