After adjustment on BP and HR , PWV significantly decreased with valsartan [ -0.37 m/s ( -0.70 to -0.08 ) at W8 and -0.43 ( -0.76 to -0.10 ) m/s at W24 ] , whereas no significant change was observed after atenolol [ -0.16 m/s ( -0.49 to 0.17 ) at W8 and -0.05 ( -0.35 to 0.44 ) m/s at W24 ] .