Based on this assumption a novel treatment for tonal tinnitus - tailor-made notched music training ( TMNMT ) ( Proc Natl Acad Sci USA 107:1207 -1210 , 2010 ; Ann N Y Acad Sci 1252:253 -258 , 2012 ; Frontiers Syst Neurosci 6:50 , 2012 ) has been introduced and will be tested in this clinical trial on a large number of tinnitus patients .