There were no differences in major bleeding ( 12 patients for tinzaparin vs 11 patients for warfarin ; HR , 0.89 [ 95 % CI , 0.40-1 .99 ] ; P = .77 ) or overall mortality ( 150 patients for tinzaparin vs 138 patients for warfarin ; HR , 1.08 [ 95 % CI , 0.85-1 .36 ] ; P = .54 ) .