Intragastric pH percentage times greater than 4 , 5 , and 6 were 86.61 19.45 % , 83.30 22.06 % , and 76.86 25.35 % , respectively , in the pretreatment and 85.54 19.45 % , 84.08 27.11 % , and 81.53 27.81 % , respectively , in the placebo group , without significant differences .