Change in the coronary artery score was -0.022 , -0.036 , -0.022 , and -0.015 mm ( nominal P = 0.25 , 0.99 , 0.55 ) , and change in the cumulative coronary stenosis score was -0.51 , 2.65 , 0.71 , and -0.77 % ( compared with placebo , nominal P = 0.85 for 12 mg/kg and nominal P = 0.01 for 3 mg/kg ) .