Compared with SBP 105-129 mmHg , the risk of ACR worsening increased significantly for SBP 130-139 mmHg ( HR 1.88 [ 95 % CI 1.28-2 .77 ] ; P = 0.001 ) and for SBP 140 mmHg ( 2.51 [ 1.66-3 .78 ] ; P < 0.0001 ) .