In the enhanced steroid arm there were significantly fewer days and individuals with seizures during antiparasitic treatment ( days 1-10 : 4 vs. 17 , p = 0.004 , and 1 vs. 10 , p = 0.003 , number needed to treat [ NNT ] 4.6 , relative risk [ RR ] 0.1013 , 95 % confidence interval [ CI ] 0.01-0 .74 ) and early after dexamethasone cessation ( days 11-21 : 6 vs. 27 , p = 0.014 , and 4 vs. 12 , p = 0.021 , NNT 4.0 , RR 0.33 , 95 % CI 0.12-0 .92 ) but not after day 21 .