Pairwise t test comparisons revealed differences in change in cRT at both measurements between BIG and HOME groups ( intermediate : -52 ms ; 95 % confidence interval [ CI ] , -84 / -20 ; P = .002 ; follow-up : 55ms ; CI , -105 / -6 ; P = .030 ) and between WALK and HOME groups ( intermediate : -61 ms ; CI , -120 / -2 ; P = .042 ; follow-up : -78 ms ; CI , -136 / -20 ; P = .010 ) .