The caries increment for Group 1 was 1.342.99 ( meanSD ) , 1.242.84 for Group 2 , 1.072.66 for Group 3 and 1.252.75 for Group 4 , with no statically significant differences either between Bifluorid 12 and Duraphat with the same frequency of F varnish applications or between the F groups and the control group .