The medicinal vesiculation was applied at Feishu ( BL 13 ) , Gaohuang ( BL 43 ) , Fengmen ( BL 12 ) , Mingmen ( GV 4 ) on the dog days in the summer , one treatment on the 1st dog-day , 2nd dog-day and last dog-day respectively with an interval of 10 days between two treatments .