Significant differences between the two groups were also found for changes in HAD anxiety scores ( 5.45 2.41 vs 3.34 2.43 , P < 0.05 ) , depression scores ( 5.47 2.47 vs 3.00 3.28 , P < 0.05 ) , and anxiety-depression scores ( 5.20 2.71 vs 3.60 2.56 , P < 0.05 ) .