Optimal predictors of durable sustained response to maintenance infliximab 5mg/kg were week 14 trough level 3.5 g/mL and 60 % CRP decrease ( ORs ( 95 % CI ) , 3.5 ( 1.1 to 11.4 ) and 7.3 ( 1.4 to 36.7 ) ) , respectively , in patients with raised baseline CRP ( > 8.0 mg/L ) ; area under the ROC curve was 0.75 for both predictors .