In a multivariable Cox regression analysis mortality was independently associated with an r-ADP-agg 50 % [ HR 3.324 ( 1.542-7 .165 ) ; p = 0.0022 ] , ACS-setting [ HR 3.249 ( 1.322-7 .989 ) ; p = 0.0102 ] and severely reduced LV function [ HR 5.463 ( 2.098-14 .26 ) ; p = 0.0005 ] .