Among patients taking carboplatin and pemetrexed , adding aprepitant significantly improved the complete response rate in the overall phase ( 83.8 % in the aprepitant group and 56.8 % in the control group ; OR , 0.26 ; 95 % CI , 0.08-0 .70 ; p < 0.01 ) and the delayed phase ( 86.5 % in the aprepitant group and 59.1 % in the control group ; OR , 0.23 ; 95 % CI , 0.07-0 .65 ; p < 0.01 ) .