The significant impact of the reminders could be seen by prophylaxis orders placed 6-24h after admission ( increasing from 8.6 % ( 223/2579 ) to 12 % ( 307/2555 ) ; p < 0.0001 ) and transfer ( increasing from 2.4 % ( 39/1616 ) to 3.7 % ( 63/1682 ) ; p = 0.034 ) .