BMI was markedly higher in adolescence for those with very early AR ( by 3.5 years ; = 0.70 ; 95 % confidence interval [ CI ] : 0.33-1 .07 ; P .001 ) and was also higher for those with early AR ( between 3.5 and 5 years ; = 0.34 ; 95 % CI : 0.08-0 .59 ; P = .009 ) compared with those with later AR ( > 5 years ) after full adjustment for a range of potential confounders .