Of patients who were treated with telaprevir twice daily , 74.3 % achieved SVR12 compared with 72.8 % of patients who were treated with telaprevir every 8 hours ( difference in response , 1.5 % ; 95 % confidence interval , -4.9 % to 12.0 % ) , so telaprevir twice daily is noninferior to telaprevir every 8 hours .