Bupropion appears less effective in long-term treatment of MDD than the other compared antidepressants , with exception of fluoxetine ( p = 0.09 ) , amitriptyline ( p = 0.13 ) , fluvoxamine ( p = 0.83 ) , venlafaxine ( p = 0.5 ) , and trazodone ( p = 0.58 ) .