Reduction in risk , relative to Rq4 , of having sustained IOP > 21 mmHg over 96 weeks was 62 % ( 95 % confidence interval [ CI ] , 36 % -78 % ) , 50 % ( 95 % CI , 19 % -70 % ) , and 69 % ( 95 % CI , 45 % -84 % ) for 2q4 , 2q8 , and 0.5 q4 , respectively .