In Study 2 ( HZC112352 ) ( intent-to-treat n : FF/VI = 259 ; FP/SAL = 252 ) and Study 3 ( RLV116974 ) ( intent-to-treat n : FF/VI = 412 ; FP/SAL = 416 ) , the increase from baseline in 0-24 h wmFEV ( 1 ) was not significantly greater with FF/VI than FP/SAL ( 29 mL , P = 0.267 ; 25 mL , P = 0.137 ) .