There was no difference in APACHEII score on day 1 and day 3 between control group and treatment group ( 1 day : 19.33 5.90 vs. 20.31 4.97 , t = 0.775 , P = 0.441 ; 3 days : 18.69 4.88 vs. 17.41 3.83 , t = 1.272 , P = 0.207 ) .