Supplementation of -3 PUFAs effectively decreased the LPS-induced PBMC expression of RANTES ( Regulated upon Activation , Normal T cell Expressed and Secreted ) and MCP-1 ( Monocyte Chemotactic Protein-1 ; unadjusted P = 0.04 and 0.06 ; adjusted for demographics P = 0.02 and 0.05 , respectively ) .