The Asthma Control Questionnaire score change over 1 year improved significantly more in the FENO-guided group ( -0.17 [ interquartile range { IQR } , -0.67 to 0.17 ] vs 0 [ -0.33 to 0.50 ] ; P = .045 ) , whereas the Mini Asthma Quality of Life Questionnaire score did not ( 0.23 [ IQR , 0.07-0 .73 ] vs 0.07 [ IQR , -0.20 to 0.80 ] ; P = .197 ) .