This was a single-center , randomized , open-label , three-period crossover study conducted in 26 fasted healthy adults ( mean weightstandard deviation , 70.411.7 kg ) assigned to single-dose oral MPH-MLR 80mg capsule or sprinkles with applesauce , or Ritalin IR 25mg ( 15mg and 120mg tablet ) administered at 0 , 4 , and 8 hours .