In addition , 38 genotype 1b patients received asunaprevir ( 200mg ) twice - ( DUAL A1 ) or once-daily ( DUAL A2 ) ; 36 genotype 1a and 5 genotype 1b patients received asunaprevir twice - ( QUAD B1 ) or once-daily ( QUAD B2 ) plus PegIFN/RBV ; and 18 genotype 1a and 4 genotype 1b patients received asunaprevir twice-daily plus ribavirin ( TRIPLE B3 ) .