Weight loss greater than 10 % occurred in 25.2 % with liraglutide ( 3.0 mg ) and 15.9 % with liraglutide ( 1.8 mg ) vs 6.7 % with placebo ( estimated difference for liraglutide [ 3.0 mg ] vs placebo , 18.5 % [ 95 % CI , 12.7 % to 24.4 % ] , P < .001 ; for liraglutide [ 1.8 mg ] vs placebo , 9.3 % [ 95 % CI , 2.7 % to 15.8 % ] , P = .006 ) .