Localized clear cell renal cell carcinoma patients meeting 1 or both of the following criteria were enrolled in a prospective phase II trial , including radical or partial nephrectomy likely to yield a glomerular filtration rate of less than 30 ml/minute/1 .73 m ( 2 ) , or partial nephrectomy high risk due to high complexity ( R.E.N.A.L. 10 to 12 ) or tumor adjacent to hilar vessels .