Log TIMP1 , log MMP1 , and log MMP1/TIMP1 ratio levels were higher in the HTLEF group than the HTNEF group ( 12.3 0.3 vs 11.8 0.1 [ P < .0001 ] , 9.1 0.3 vs 8.0 0.2 [ P < .0001 ] , and -3.3 0.3 vs -3.8 0.2 [ P < .0001 ] , respectively ) .