GRAVITY ( NCT00525824 ) compared efficacy , safety and effect on biomarkers of RSV10/EZE10 and RSV20/EZE10 vs. simvastatin 40 mg and 80 mg plus EZE10 ( SIM40/EZE10 and SIM80/EZE10 ) in patients with coronary heart disease ( CHD ) or CHD risk equivalent .