Subjects pretreated with ice reported less pain from arterial puncture compared with subjects in the control group ( mean visual analog scale 13.8 16.9 vs 25 23 mm , P = .01 ; median visual analog scale 7 mm , interquartile range ( IQR ) 1.5-19 vs 20 mm , IQR 4.5-38 .5 mm , P = .01 ) .