Those treated with mistletoe did better on all 6 functional scales and on 7 of 9 symptom scales , including pain ( 95 % confidence interval [ CI ] -29 to -17 ) , fatigue ( 95 % CI -36.1 to -25.0 ) , appetite loss ( 95 % CI -51 to -36.7 ) , and insomnia ( 95 % CI -45.8 to -28.6 ) .