QMVC improved in both groups ( fosinopril : 1.1 kg ; 95 % CI , 0.03-2 .2 ; P = .045 vs placebo : 3.6 kg ; 95 % CI , 2.1-5 .0 ; P < .0001 ) with a greater increase in the placebo arm ( between-group , P = .009 ) .