A single nucleotide polymorphism ( SNP ) of the patatin-like phospholipase-3 ( PNPLA3 ) / adiponutrin gene ( rs738409 C > G ) is strongly associated with nonalcoholic fatty liver disease ; to our knowledge , no data are available on the impact of this PNPLA3 SNP on liver and metabolic outcomes during pregnancy in patients with gestational diabetes ( GD ) .