After 2 doses of an H7N9 formulation containing 15 g of hemagglutinin given without adjuvant , with AS03 adjuvant , or with MF59 adjuvant , the proportion achieving an HIA titer of 40 or higher was 2 % ( 95 % CI , 0 % -7 % ) without adjuvant ( n = 94 ) , 84 % ( 95 % CI , 76 % -91 % ) with AS03 adjuvant ( n = 96 ) , and 57 % ( 95 % CI , 47 % -68 % ) with MF59 adjuvant ( n = 92 ) ( P < .001 for comparison of the AS03 and MF59 schedules ) .