GMRs and 90 % CIs for hypericin , the active component of SJW , ( with boceprevir versus alone ) AUC ( 0-8 ) , C ( max ) and C ( 8 ) were 1.23 ( 1.10-1 .38 ) , 1.32 ( 1.16-1 .52 ) and 1.37 ( 1.19-1 .58 ) , respectively .