Two-year mean reductions in initial body weight were 2.9 % ( 95 % Credible Interval = 1.7-4 .3 ) , 3.5 % ( 2.0-4 .8 ) , 6.7 % ( 5.3-7 .9 ) , and 6.8 % ( 5.5-8 .1 ) for the control , low - , moderate - , and high-dose conditions , respectively .