Participants who received the HC/HC diet had a smaller total number of adverse events than did those in the other groups ( 23 in the HC/HC group vs 42 in the control group vs 48 in the HF/HC group ; overall , p = 0.06 ; HC/HC vs control , p = 0.06 ) and significantly fewer serious adverse events than did those on the control diet ( none vs nine ; p = 0.0005 ) .