Multivariate analyses confirmed age ( p = 0.005 , OR = 3.78 ) , female gender ( p = 0.003 , OR = 2.91 ) , longer cross-clamp time ( > 60 minutes ) ( p = 0.001 , OD = 0.97 ) , body surface area < 1.6 m2 ( p = 0.001 , OR = 6.01 ) and crystalloid cardioplegia ( p < 0.001 , OR = 0.19 ) as predictor of intraoperative hemodilution .