In univariate analyses , symptom severity was associated with a higher risk of CV death or HF hospital stay ( fatigue : group 3 , 49 % [ n = 810 ] , vs. group 1 , 30 % [ n = 160 ] ; dyspnea : group 3 , 50 % [ n = 918 ] , vs. group 1 , 28 % [ n = 82 ] ) and all-cause mortality ( fatigue : group 3 , 38 % [ n = 623 ] , vs. group 1 , 24 % [ n = 130 ] ; dyspnea : group 3 , 38 % [ n = 697 ] , vs. group 1 , 23 % [ n = 66 ] , log-rank p < 0.0001 for all ) .