( 1 ) After treatment , effective rate of two groups was 91.2 % and 87.0 % , there was no obvious difference ( P > 0.05 ) ; After follow up about 1 year , effective rate of two groups was 76.5 % and 73.9 % , there was no obvious difference ( P > 0.05 ) ; ( 3 ) After follow up about 3 years and 5 years , disease free survival ( DFS ) of two groups was 61.3 % , 47.6 % and 43.5 % , 21.4 % , there was obvious difference ( P < 0.05 ) .