Among them , 81 patients received non-bismuth quadruple therapy ( esomeprazole 20 mg , amoxicillin 1 000 mg , clarithromycin 500 mg and tinidazole 500 mg given twice daily for 7 days ) ; 82 standard triple therapy ( esomeprazole 20 mg , amoxicillin 1 000 mg and clarithromycin 500 mg given twice daily ) for 7 days and 83 standard triple therapy for 10 days .