It was improved obviously at the each time point after treatment in the observation group as compared with that in the control group ( 3.34 + / - 2.41 vs 2.64 + / - 11.56 , 6.20 + / - 1.46 vs 4.34 + / - 1.64 , 11.26 + / - 2.63 vs 8.75 + / - 2.18 , all P < 0.05 ) .