Indication of lack of mucosal healing was found in the group treated with placebo/Nissle , since only 4 ( 29 % ) of the 14 patients , who completed the study , reported no blood in stools at week 12 ( p < 0.02 ) , compared to 63 % , 67 % and 65 % in groups treated with Cipro/Nissle , Cipro/placebo and placebo/placebo , respectively .