At six week , intention-to-treat and per-protocol analyses of the left-eye Schirmer I test results showed an improved difference of 1.36 mm/5 min ( 95 % CI : 0.03 to 2.69 mm/5 min ) and 1.35 mm/5 min ( 95 % CI : 0.04 to 2.73 mm/5 min ) , respectively , and those of the right-eye Schirmer I test results showed an improved difference of 1.12 mm/5 min ( 95 % CI : 0.02 to 2.22 mm/5 min ) and 1.12 mm/5 min ( 95 % CI : -0.02 to 2.27 mm/5 min ) , respectively .