In a 26-week , double-blind trial , patients with type 2 diabetes ( A1C 7.5-10 .0 % [ 58-86 mmol/mol ] ) on basal insulin ( 20-40 units ) and metformin with or without sulfonylurea/glinides were randomized ( 1:1 ) to once-daily IDegLira + metformin or IDeg + metformin with titration aiming for fasting plasma glucose between 4 and 5 mmol/L .