Addition of gemcitabine did not increase pCR : 70 ( 17 % , 95 % CI 14-21 ) of 404 patients in the epirubicin and cyclophosphamide then paclitaxel group achieved pCR compared with 71 ( 17 % , 14-21 ) of 408 patients who received additional gemcitabine ( p = 098 ) .