Compared with ABVD , inferiority of the dacarbazine-deleted variants was detected with 5 year differences of -11.5 % ( 95 % CI -18.3 to -4.7 ; HR 2.06 [ 1.21 to 3.52 ] ) for ABV and -15.2 % ( -23.0 to -7.4 ; HR 2.57 [ 1.51 to 4.40 ] ) for AV .