Using the database of our ongoing randomised , placebo-controlled study ( ClinicalTrials.gov NCT01406678 ) , we assessed the troponin I concentration area under curve ( measurements : baseline , 1 , 6 , 12 , 24 , 48 , and 72 h post-operatively ) in sulphonylurea-treated diabetics ( n = 27 ) and non-diabetics ( n = 230 ) without and with remote ischaemic pre-conditioning ( three 5-min periods of left upper arm ischaemia with 5-min reperfusion each ) during isoflurane anaesthesia before two - to three-vessel coronary artery surgery .