In this open , phase II , randomized study ( NCT01090453 ) , 480 infants from Germany , France and Canada received the heptavalent vaccine ( Hepta group ) or hexavalent and monovalent MenC control vaccines ( HexaMenC group ) co-administered with a 13-valent pneumococcal conjugate vaccine at 2 , 4 and 12 months of age .