The mean number of NCT-A and MMSE scores improved significantly in patients in the HMG ( 0 day , 102.0024.49 for NCT-A , 18.552.89 for MMSE ; 15 days , 78.3022.55 for NCT-A , 24.202.78 for MMSE ) compared with patients in the CG after 15 days of follow-up ( 0 day , 103.0024.98 for NCT-A , 17.902.99 for MMSE ; 15 days , 95.6524.34 for NCT-A , 18.853.12 for MMSE ) , P < 0.05 ; the mean number of P300 latency ( ms ) and wave amplitude ( V ) improved significantly among patients in the HMG after 15 days of treatment ( 0 day , 341.9014.04 for latency , 8.401.73 for wave amplitude ; 15 days , 305.4523.95 for latency , 13.003.80 for wave amplitude ) compared with patients in the CG after 15 days of follow-up ( 0 day , 343.8514.88 for latency , 8.291.77 for wave amplitude ; 15 days , 340.4013.06 for latency , 8.501.82 for wave amplitude ) , P < 0.05 .