Empiric antibiotic therapy in FN episodes with bacteremia was highly effective if not only intrinsic and reported antimicrobial susceptibilities were considered but also the purposeful omission of coverage for coagulase-negative staphylococci and enterococci was taken into account [ 81 % ( 95 % confidence interval : 68-90 ) vs. 96.6 % ( 95 % confidence interval : 87-99 .4 ) , P = 0.004 ] .