The mean percentage reduction from baseline at the end of eight minutes of tablet sucking was 39 % in the control group ( p < 0.001 ) and 62 % in the test group ( p < 0.001 ) ; one hour later it was 6 % in the control group and 30 % in the test group ( p < 0.001 ) , and two hours later it was 2 % in the control group and 18 % in the test group ( p < 0.001 ) .