This Phase 3 , international , randomized , single-blind , controlled trial ( FINISH-3 ) compared the efficacy and safety of Fibrocaps , a ready-to-use , dry-powder fibrin sealant containing human plasma-derived thrombin and fibrinogen , vs gelatin sponge alone for use as a hemostat for surgical bleeding in 4 indications ( ie , spinal , hepatic , vascular , soft tissue dissection ) .