In patients who did not receive amiodarone , the stroke or systemic embolism rate was 1.29 % / year versus 1.57 % / year ( HR : 0.82 , 95 % CI : 0.68 to 1.00 ) , death was 3.43 % / year versus 3.68 % / year ( HR : 0.93 , 95 % CI : 0.83 to 1.05 ) , and major bleeding was 2.18 % / year versus 3.03 % / year ( HR : 0.72 , 95 % CI : 0.62 to 0.84 ) .