Reversal of diluted thrombin time ( dTT ) , ecarin clotting time ( ECT ) , activated partial thromboplastin time ( aPTT ) , and thrombin time ( TT ) were secondary endpoints assessed by measuring the area under the effect curve from 2 h to 12 h ( AUEC2-12 ) after dabigatran etexilate ingestion on days 3 and 4 .