This was a double-blind , placebo-controlled , 2 2 factorial multicenter randomized trial of 1,708 post-myocardial infarction ( MI ) patients 50 years of age and with creatinine 2.0 mg/dL randomized to receive 40 EDTA chelation or placebo infusions plus 6 caplets daily of a 28-component multivitamin-multimineral mixture or placebo .