The National Surgical Adjuvant Breast and Bowel Project ( NSABP ) menopausal symptoms questionnaire , the Center for Epidemiological Studies Depression ( CESD ) scale , the Hospital Anxiety and Depression Scale ( HADS ) , the Pittsburgh Sleep Quality Index ( PSQI ) , the hot flash daily diary , the Hot Flash-Related Daily Interference Scale ( HFRDI ) , and the European quality-of-life survey ( EuroQol ) were used to assess PROs at baseline and at 4weeks , 8 weeks , and 12 weeks .