Patients taking basal insulin ( with or without oral agents ) with HbA1c 7-10 .5 % ( 53-91 mmol/mol ) entered a glargine standardization period , followed by randomization to albiglutide , 30 mg weekly ( n = 282 ) , subsequently uptitrated to 50 mg , if necessary , or thrice-daily prandial lispro ( n = 281 ) while continuing metformin and/or pioglitazone .