The difference between the placebo group and the losmapimod groups for mean change of 6 min walk distance was not significant : -67 m ( 95 % CI -182 to 49 ) for losmapimod 25 mg , -47 m ( -161 to 68 ) for losmapimod 75 mg , and -34 m ( -151 to 82 ) for losmapimod 15 mg .