The most frequently reported related adverse events were dizziness ( ranging from 33.9 % to 35.5 % after dose 1 ; and 16.0 % to 20.8 % after dose 2 ) and vomiting ( 30.2 % to 31.7 % , after dose 1 and 15.3 % to 17.4 % after dose 2 ) with similar proportions in the full and split MQ arms .