The objectives of this analysis were : ( 1 ) to evaluate the effect of administration time and fat or caloric content of an accompanying meal on the pharmacokinetic properties of a single dose of pregabalin CR ( 330mg ) relative to a single dose of pregabalin IR ( 300mg ) ; ( 2 ) to evaluate the pharmacokinetic properties of a single dose of pregabalin CR administered fasted relative to a single dose of pregabalin CR administered immediately after food ; and ( 3 ) to determine the safety and tolerability of single-dose administration of pregabalin CR and IR with and without food .