Baseline mean ( standard deviation ) values were pain visual analog scale of 6.1 ( 1.6 ) and 6.3 ( 1.7 ) , P = 0.562 ; swelling visual analog scale of 5.9 and 6.4 , P = 0.466 ; chronic disease activity index of 17.8 and 16.8 , P = 0.366 ; and Health Assessment Questionnaire of 0.8 and 0.7 , P = 0.238 , in the high - and low-dose groups , respectively .