Immunogenicity endpoints were rates of seroresponse to pertussis toxoid , filamentous hemagglutinin , pertactin and fimbriae types 2 and 3 ; rates of seroprotection against ( Hib ) polyribosylribitol phosphate capsular polysaccharide , hepatitis B surface antigen , diphtheria toxoid , tetanus toxoid and poliovirus types 1 , 2 and 3 ; and geometric mean titers to all vaccine antigens .