In residual tumour patients ( n = 81 ) median PFS was 5.6 versus 4.0 months , ( hazard ratio ( HR ) , 0.87 ; 95 % confidence interval ( CI ) , 0.55-1 .37 ) , for patients without residual tumour ( n = 61 ) it was 10.6 versus 9.9 months , ( HR , 1.01 ; 95 % CI , 0.57-1 .77 ) .