ESV reduction , EF increase , and NYHA class reduction relative to BASELINE were significantly greater in the MPP group than in the CONV group ( ESV : -21.0 13.9 vs. -12.6 11.1 % , P = 0.03 ; EF : +9.8 5.1 vs. +2.0 7.8 percentage points , P < 0.001 ; NYHA : -1.05 0.22 vs. -0.72 0.46 functional classes , P = 0.006 ) .