Doses were 5 , 10 , 25 , 50 ( fed/fasted ) , 100 and 150mg ( Caucasian males , 18-55years ) , 25mg ( Caucasian males , > 65years and Caucasian females , 18-55years ) , 25 , 50 , 100 and 150mg ( Japanese males , 18-55years ) .