Patients with and without CADI cerebrovascular disease were differently treated with clopidogrel ( 27.3 % and 4.8 % , p < 0.001 ) , any antiplatelet/anticoagulant therapy ( 98.7 % and 83.3 % , p < 0.001 ) and beta-blockers ( 46.8 % and 16.0 % , p < 0.001 ) .