In left bundle branch block ( LBBB ) patients with a CRT-D , weight loss was associated with an especially high risk of HF or death ( HR 2.23 , 95 % CI 1.36-3 .65 ; P = .002 ) and of death alone ( HR 2.33 , 95 % CI 1.07-5 .06 ; P = .03 ; interaction P = .26 ) .