Mean pharmacokinetic parameter values of RFP obtained for formulations A , B , C , and D products were 11.42 3.41 g/ml , 7.86 5.78 g/ml , 13.05 6.80 g/ml , and 16.18 3.87 g/ml , respectively , for peak plasma concentration ( C max ) , 91.43 30.82 gh-1ml-1 , 55.49 37.58 gh-1ml-1 , 96.50 47.24 gh-1ml-1 , 101.47 33.07 gh-1ml-1 , respectively , for area under the concentration-time curve ( AUC 0-24 h ) .