In multivariate analysis of time to CHD death , Agatston scores of 1-100 , 101-1000 , and greater than 1000 ( reference category 0 ) were associated with hazard ratios of 1.27 ( 95 % confidence interval : 0.69 , 2.53 ) , 3.57 ( 95 % confidence interval : 2.14 , 7.48 ) , and 6.63 ( 95 % confidence interval : 3.57 , 14.97 ) , respectively ; hazard ratios for summed segmented vessel-specific scores of 1-5 , 6-11 , and 12-30 ( reference category 0 ) were 1.72 ( 95 % confidence interval : 1.05 , 3.34 ) , 5.11 ( 95 % confidence interval : 2.92 , 10.94 ) , and 6.10 ( 95 % confidence interval : 3.19 , 14.05 ) , respectively ; and hazard ratios for overall visual assessment of mild , moderate , or heavy ( reference category none ) were 2.09 ( 95 % confidence interval : 1.30 , 4.16 ) , 3.86 ( 95 % confidence interval : 2.02 , 8.20 ) , and 6.95 ( 95 % confidence interval : 3.73 , 15.67 ) , respectively .