Using analyses of covariance on a per-protocol sample , there were no differences noted between the MBCR and SET groups with regard to the telomere/single-copy gene ratio , but a trend effect was observed between the combined intervention group and controls ( F [ 1,84 ] , 3.82 ; P = .054 ; ( 2 ) = .043 ) ; TL in the intervention group was maintained whereas it was found to decrease for control participants .