However , the effect of GLP-1 on MGU was negatively correlated to baseline MGU both during normo - and hypoglycemia , ( P = 0.006 , r ( 2 ) = 0.64 and P = 0.018 , r ( 2 ) = 0.64 , respectively ) and changes in MGU correlated positively with the level of insulin resistance ( HOMA 2IR ) during hypoglycemia , P = 0.04 , r ( 2 ) = 0.54 .