The proportion of patients with a 50 % increase in alanine aminotransferase activity did not differ between the standard ( 9/110 ) and shorter modified ( 13/112 ) regimens ( adjusted odds ratio 060 , 975 % CI 020-183 ) ; however , the proportion was higher with ondansetron ( 16/111 ) than with placebo ( 6/111 ; 330 , 101-1072 ; p = 0024 ) .