In multivariable analyses , multivitamin use compared with no use was not associated with major CVD events ( HR : 1.01 ; 95 % CI : 0.89 , 1.15 ) , MI ( HR : 1.04 ; 95 % CI : 0.84 , 1.27 ) , stroke ( HR : 0.99 ; 95 % CI : 0.83 , 1.18 ) , or CVD death ( HR : 1.10 ; 95 % CI : 0.84 , 1.45 ) .