The increase ( 30 ) group showed a numerically but not significantly higher remission rate and a significantly greater decrease in the HDRS-17 total score at week 6 than the stay ( 15 ) group ( 34.7 % [ 8 of 23 patients ] vs 14.3 % [ 3 of 21 patients ] , P = .2 ; least squares mean , -15.8 vs -10.9 , P = .003 ) .