Mean reduction in glycemic parameters at Week 12 ( HbA1c : -0.56 % vs -0.72 % , p = 0.394 ; FBG : -0.99 mmol/L vs -1.05 mmol/L , p = 0.878 ; PPG : -1.93 mmol/L vs -1.52 mmol/L , p = 0.423 ) and Week 24 ( HbA1c : -0.87 % vs -0.90 % , p = 0.909 ; FBG : -0.79 mmol/L vs -1.02 mmol/L , p = 0.648 ; PPG : -1.77 mmol/L vs -1.36 mmol/L , p = 0.415 ) was not significantly different between the hydroxychloroquine and pioglitazone groups .