Recruitment through a mailed study brochure at the time of booking-in to the hospital resulted in the largest number of participants in the RCT ( 16/32 ; 50 % ) , and resulted in considerably earlier recruitment ( 50 % in first trimester , 50 % second trimester ) compared to recruitment through the antenatal clinic waiting room ( 86 % in second trimester , 14 % third trimester ) .