Key eligibility criteria are age 30 years , BMI of 24 ( 22.5 for Asian Americans ) to 42 kg/m ( 2 ) , increased risk for diabetes ( defined as meeting two of three glycemic criteria for prediabetes established by the American Diabetes Association [ fasting glucose 100-125 mg/dL ( 5.5-6 .9 mmol/L ) , 2-h postload glucose after 75-g glucose load 140-199 mg/dL ( 7.7-11 .0 mmol/L ) , hemoglobin Ac 5.7-6 .4 % ( 39-46 mmol/mol ) ] ) , and no hyperparathyroidism , nephrolithiasis , or hypercalcemia .