Loaded regimen ameliorated the mean reduction of day 7 postoperative mean change of serum calcium level by 0.330.99 mg/dl and median change by 2.88 mg/dl ( min , max = -0.80 , 5.64 ) compared with titrate regimen mean change ofserum calcium level by 2.682.16 mg/dl ; median change 0.28 mg/dl ( min , max = -0.84 , 1.80 ) with significance , p = 0.036 .