In addition , a significant reduction in serum LDL-cholesterol ( -0.23 0.79 vs +0.26 0.74 mmol/l , p = 0.02 ) and total cholesterol : HDL-cholesterol ratio ( -0.49 1.09 vs +0.18 0.37 , p = 0.003 ) and a significant elevation in HDL-cholesterol levels ( +0.15 0.25 vs -0.02 0.24 mmol/l , p = 0.01 ) was seen after intervention in the calcium-vitamin D group compared with placebo .