Baseline hyponatremia did not predict development of hypotension or worsening renal function after 1month in patients treated with trandolapril compared with placebo ( 12219.1 mm Hg vs 123.220.4 mm Hg [ P = .84 ] ; and creatinine clearance 57.421.4 mL/min vs 55.221.0 mL/min [ P = .8 ] ) .