After two consecutive months consumption of Royal Jelly , PMS score had decreased from 23.17 17.43 to 11.42 14.58 ( mean change : 11.75 ; 95 % confidence interval [ CI ] : 8.31-15 .19 ) and in Placebo , PMS score changed from 21.48 16.39 to 20.27 15.76 ( mean change : 1.20 ; 95 % CI : -1.69 to 4.10 ) .