We explored the effect of randomization to atorvastatin 80 mg/d or placebo on the change in estimated glomerular filtration rate ( eGFR ; using the 4-component Modification of Diet in Renal Disease Study equation ) in SPARCL subjects ( n = 4731 ) with ( eGFR , < 60 mL/min per 1.73 m2 ; n = 3119 ) and without ( eGFR , 60 mL/min per 1.73 m2 ; n = 1600 ) chronic kidney disease overall and by glycemic status at baseline .