There were significant reductions in the median volume of fluid used ( 4,200 mL [ range 1,300-21 ,000 mL ] compared with 9,800 mL ( range 1,500-23 ,000 mL ; P = .004 ) and fluid intravasation ( 0 mL [ range 0-3 ,100 ] compared with 300 mL [ range -150 -3,150 mL ; P = .029 ) in the vasopressin group .