Among these patients , 45.9 % ( 273 out of 595 ) had a family history of asthma , 30.6 % ( 182 out of 595 ) had allergic rhinitis , 23.9 % ( 142 out of 595 ) increased peripheral blood eosinophilia , 6.1 % ( 36 out of 595 ) exhibited total IgE increase , 40.0 % ( 238 out of 595 ) had a recurrent history of wheezing , and 64.0 % ( 381 out of 595 ) had a family history of eczema .