In the multivariate analysis , history of migraine ( hazard ratio [ HR ] , 5.737 ; P = .012 ) , narrower neuroretinal rim width at baseline ( HR , 2.91 ; P = .048 ) , use of systemic - blockers ( HR , 5.585 ; P = .036 ) , low mean systolic blood pressure ( HR , 1.06 ; P = .02 ) , and low mean arterial ocular perfusion pressure during follow-up ( HR , 1.172 ; P = .007 ) were significant and independent risk factors for disc hemorrhage detection .