The treatment in GEMOXEL arm consisted of GEM 1,000 mg/m ( 2 ) as a 30-min intravenous infusion on days 1 , 8 , 15 , 22 , L-OHP 100 mg/m ( 2 ) i.v. on day 2 , and CAP 1,500 mg/m ( 2 ) / day in two divided doses on days 1-14 , every 21 days ( one cycle ) .