( 2 ) After 8 weeks , LVFS was significantly increased ( from ( 34.62 5.76 ) % to ( 35.90 4.99 ) % , P = 0.027 ) and serum Hcy ( from ( 18.08 1.81 ) mol/L to ( 16.06 10.10 ) mol/L ) , PHQ-9 ( from 8.14 3.98 to 6.28 2.87 ) and GAD-7 ( from 9.52 4.98 to 6.48 3.84 ) were significantly reduced in treatment group ( all P < 0.05 ) compared to baseline .