In 7 , 14 and 21 days of treatment , the total effective rates were 50.0 % ( 16/32 ) , 68.8 % ( 22/32 ) and 78.1 % ( 25/32 ) in the observation group and were 69.0 % ( 20/29 ) , 72.4 % ( 21/29 ) and 82.8 % ( 24/29 ) in the control group .