The adjusted mean change in FGF23 from baseline to week 12 was 7.7 pg/ml in the TDF/VITD group , compared with -1.7 ( no-TDF/VITD , P = 0.010 ) , -1.3 ( TDF/PL , P = 0.006 ) and 1.1 ( no-TDF/PL , P = 0.035 ) .