In the Computer Assisted Management in Early RA ( CAMERA ) trials , patients with early RA , disease duration < 1 year , no prior use of DMARDs ) had been randomised to a methotrexate ( MTX ) - based tight control strategy or usual care ( CAMERA study ) or to 10 mg/d prednisone or placebo both added from start to a MTX-based tight control strategy ( CAMERA-II study ) .