The eradication rates of the hybrid and sequential therapy groups were 81.1 % ( 73/90 ; 95 % confidence interval [ CI ] = 73.0-89 .2 % ) and 79.8 % ( 75/94 ; 95 % CI = 71.7-87 .9 % ) , respectively , by intention-to-treat analysis ( P = 0.821 ) .