At week 7 , mean SBP reductions from baseline were -37.5 mmHg ( 1 mmHg = 0.133 kPa ) and -26.9 mmHg in the T80/H25 and T80 groups ( adjusted mean difference , -10.6 mmHg ; 95 % confidence interval ( CI ) , -15.6 to -5.7 ) .