The levels of IL-1 ( 35 12 vs 47 18 , P < 0.05 ) ng/L , IL-6 ( 49 21 vs 62 27 , P < 0.05 ) ng/L , TNF - ( 39 16 vs 52 25 , P < 0.05 ) ng/L and CRP ( 95 41 vs 125 45 , P < 0.05 ) mg/L were also lower in the slight sedation group than those in the conventional group .