In AIDS Clinical Trials Group A5212 , a randomized , double-blind , placebo-controlled study , 99 HIV-infected patients on ART with plasma HIV-1 RNA levels 200 copies per milliliter for 6 months and CD4 lymphocyte counts < 200 cells per cubic milliliter were randomized 1:1:1:1 to receive once daily intravenous administration of placebo or 20 , 40 , or 60 g/kg of palifermin on 3 consecutive days .