In all patients at baseline and after 12months we measured CA-IMT , total cholesterol ( TC ) , high-density lipoprotein cholesterol ( HDL-C ) , low-density lipoprotein cholesterol ( LDL-C ) , 25-hydroxyvitamin D ( 25OHD ) , bone alkaline phosphatase ( B-ALP ) , type I collagen carboxy telopeptide ( CTX ) , osteocalcin ( OC ) , fibroblast growth factor 23 ( FGF-23 ) and sclerostin .