Significant differences were observed between the ET and the control groups in raw mean deltas ( = post - - pre-intervention ) : 6MWD , 81 m , p < 0.001 ; VO2 peak , 2.6 ml/kg/min , p = 0.002 ; work rate , 22 W , p < 0.001 ; anaerobic threshold , 3.1 ml/kg/min , p < 0.001 , and FVC % predicted , 6 % , p = 0.038 .