Similarly , the distance score of the WIQ improved by 12.5 ( 95 % CI , 6.4 to 18.7 ) vs 4.8 ( 95 % CI , -0.2 to 9.8 ) with GM-CSF compared with placebo ( mean difference in change , 7.9 [ 95 % CI , 0.2 to 15.7 ] , P = .047 ) .