PASI 75 response rates were lower in patients with nail psoriasis compared with patients without nail psoriasis at week 8 ( 53.0 % vs. 62.9 % ; OR , 0.68 ; P = 0.019 ) and week 16 ( 65.0 % vs. 73.0 % ; OR , 0.70 ; P = 0.052 ) .