In patients with , compared with patients without MDI , fever [ median , 5 ( interquartile range : 3-8 ) vs. 2 ( interquartile range : 1-3 ) days , P < 0.001 ] and hospitalization [ 10 ( 6-14 ) vs. 5 ( 3-8 ) days , P < 0.001 ] lasted longer , transfer to the intensive care unit was more likely [ 13 of 95 ( 14 % ) vs. 7 of 346 ( 2.0 % ) , P < 0.001 ] , and antibiotics were given longer [ 10 ( 7-14 ) vs. 5 ( 4-7 ) days , P < 0.001 ] .