The risk of VTA was reduced in patients with LVEF > 50 % ( hazard ratio [ HR ] , 0.24 ; 95 % confidence interval [ CI ] , 0.07-0 .82 ; P = 0.023 ) and LVEF of 36 % to 50 % ( HR , 0.44 ; 95 % CI , 0.28-0 .68 ; P < 0.001 ) .