In comparison with controls , the intervention led to significant improvement of knowledge from baseline to 3-month follow-up ( caregivers : IG 3.2 / 13.2 improvement/baseline vs CG 0.7 / 12.6 ; P < 0.001 ; patients : IG 3.9 / 10.8 vs 1.3 / 12.6 ; P < 0.001 ) .