Compared with EBUS-TBNA , EUS-FNA was associated with a shorter duration of procedure ( median , 15.3 min vs 11.3 min ; P < .001 ) , lower doses of IV midazolam ( mean , 4.4 mg vs 4 mg ; P = .02 ) and intraairway lidocaine ( mean , 303 mg vs 189 mg ; P < .001 ) , less frequent oxygen desaturations ( 23 of 55 vs two of 55 , P < .001 ) , and higher operator satisfaction ( P < .001 ) .