There was no significant difference in OS ( 3-year OS 94.3 % [ GCP ] vs 92.3 % [ control ] ; hazard ratio 1.05 ; 1-sided P = .494 ] ) , disease-free survival ( hazard ratio 0.77 , 95 % confidence interval 0.44-1 .35 , P = .362 ) , and distant metastases-free survival ( hazard ratio 0.80 , 95 % confidence interval 0.38-1 .67 , P = .547 ) between the 2 arms .