Patients with venous thromboembolism had higher 5-year event rates for the composite of death , myocardial infarction , and stroke , as compared with patients without venous thromboembolism ( 10.7 % vs 5.9 % ; P < .001 ; adjusted hazard ratio 2.12 ; 95 % confidence interval , 1.36-3 .31 ; P = .001 ) .