The aim of the current study was to analyze the type of variations in expression profiles of matrix metalloproteinase 2 ( MMP2 ) , matrix metalloproteinase 9 ( MMP9 ) , tissue inhibitor of metalloproteinase 2 ( TIMP2 ) , and vascular endothelial growth factor A ( VEGFA ) before and after radiochemotherapy in patients with locally advanced FIGO stage Ib-IIb cervical cancer .