127 ( 76 % ) patients assigned to the SAFETY intervention died or had an unplanned readmission ( median event-free survival 183 days [ IQR 116-409 ] ) and 137 ( 82 % ) people allocated standard management achieved a coprimary outcome ( 199 days [ 116-249 ] ; hazard ratio 097 , 95 % CI 076-123 ; p = 0851 ) .