Out-of-hospital time greater than 60 minutes was not associated with worse outcomes after accounting for important confounders in the shock cohort ( adjusted odds ratio [ aOR ] 1.42 ; 95 % confidence interval [ CI ] 0.77 to 2.62 ) or traumatic brain injury cohort ( aOR 0.77 ; 95 % CI 0.51 to 1.15 ) .