The crude excess risk of death in non-eligible patients ( HR 1.96 ; 95 % CI 1.36 to 2.77 ; P < 0.001 ) was reduced after adjustment for risk factors which differed in the two cohorts including age , blood pressure , phosphate , CRP , smoking , diabetes , triglycerides , cardiovascular comorbidities and history of neoplasia ( HR 1.60 ; 95 % CI 1.10 to 2.35 ; P = 0.017 ) and almost nullified after including in the same model also information on deambulation impairment ( HR 1.16 ; 95 % CI 0.75 to 1.80 ; P = 0.513 ) .