After treatment , serum levels of of IL-12 and TNF-alpha were 104.67 + / - 16.84 and 183.01 + / - 24.95 in the NG group , 109.04 + / - 16.81 and 179.87 + / - 23.45 in the combined treatment group , significantly lower than before treatment ( P < 0.05 ) .