In CABG group , ET-1 levels were significantly elevated vs. baseline in arterial : ART-T2 vs. ART-T0 ( 1.83 1.81 vs. 0.76 1.07 fmol/mL , p = 0.05 ) , pulmonary : SG-T2 vs. SG-T0 ( 2.70 2.75 vs. 0.39 0.28 fmol/mL , p < 0.001 ) and SG-T3 vs. SG-T0 ( 1.56 0.28 vs. 0.39 0.28 fmol/mL , p < 0.001 ) , and coronary circulation CS-T2 vs. CS-T1 ( 1.12 0.49 vs. 0.27 0.09 fmol/mL , p = 0.01 ) .