Between May 22 , 2012 , and Oct 14 , 2013 , 1416 patients were screened for eligibility , 106 of those were randomly assigned to treatment ( 53 patients in each group , intention-to-treat population ) and 101 analysed because of patients with missing endpoints ( 48 in the renal denervation group , 53 in the control group , modified intention-to-treat population ) .