After treatment and follow-up , there were significant differences between two groups in the following : cough , sputum , pant , chest tightness , shortness of breath , lassitude score and symptom total score ( P < .05 ) ; physical , psychological , social and environment domain ( P < .05 ) of the WHOQOL-BREF ; daily living ability , social activity , depression symptoms and anxiety symptoms domain ( P < .05 ) of the COPD-QOL .