impact of NMS on : patients ' understanding of their medicines , pharmacovigilance , interprofessional and patient-professional relationships and experiences of service users and stakeholders.Economic analysis : Trial-based economic analysis ( cost per extra adherent patient ) and long-term modeling of costs and health effects ( cost per quality-adjusted-life-year ) will be conducted from the perspective of National Health Service ( NHS ) England , comparing NMS with current practice.Qualitative analysis : a qualitative study of NMS implementation in different community settings , how organizational influences affect NMS delivery , patterns of NMS consultations and experiences of professionals and patients participating in NMS , and patients receiving current practice .