Intention-to-treat analysis showed no improvement with respect to intention tremor severity ( mean [ SD ] values with memantine vs placebo : 1.05 [ 0.73 ] vs 1.89 [ 2.19 ] , P = .047 ) or BDS score ( 16.12 [ 5.43 ] vs 15.72 [ 3.93 ] , P = .727 ) at follow-up .