The sequential treatment ( AL-CML ) group was administrated amoxicillin 1g b.i.d. and lansoprazole 30mg b.i.d. for the first 5 days , followed by clarithromycin 500mg b.i.d. , metronidazole 500mg b.i.d. and lansoprazole 30mg b.i.d. for the second 5 days .