The primary aim of the trial is to compare ( 1 ) the patency rate ( primary , primary assisted , and secondary patency at 6 and 12 months ) , ( 2 ) improvement of quality of life , ( 3 ) clinical improvement ( at least 1 Rutherford category ) , and ( 4 ) wound healing and limb salvage in patients presenting with critical limb ischemia ; secondary aims include ( 1 ) cost-effectiveness by factoring procedure and hospital admission costs including rehabilitation , readmission , and reintervention costs , ( 2 ) amputation-free survival , ( 3 ) reintervention rate , and ( 4 ) 30-day operative mortality , morbidity , and wound and access complications .