From April to December 2005 , 155 frail community-dwelling COPD patients were randomly allocated either to IC ( n = 76 , age 73 ( 8 ) years , forced expiratory volume during the first second , FEV1 41 ( 19 ) % predicted ) or usual care ( n = 84 , age 75 ( 9 ) years , FEV1 44 ( 20 ) % predicted ) and followed up for 12 months .