However , the relapse rate in the observation group was significantly lower than that in control group at the end of the first ( 17.7 % vs. 50.0 % , P < 0.05 ) , second ( 29.4 % vs. 68.8 % , P < 0.05 ) and the third month ( 29.4 % vs. 87.5 % , P < 0.01 ) .