The primary outcome death and major bleeding occurred in 5.1 % with bivalirudin , 7.6 % with heparin plus routine GPI ( HR 0.67 and 95 % CI 0.46-0 .97 , P = 0.034 ) , and 9.8 % with heparins plus bailout GPI ( HR 0.52 and 95 % CI 0.35-0 .75 , P = 0.006 ) .