With ST resolution ( STR ) group as a reference , G2 - > G2 , G2 - > G3 and G3 - > G3 were associated with larger IS ( B = 4.4 , p = 0.004 ; B = 5.4 , p = 0.01 ; B = 10.2 , p < 0.001 , respectively ) , whereas G3 - > G2 was not .