Patients were randomly assigned either to conventional paclitaxel plus cisplatin ( TP ; paclitaxel 135 mg/m ( 2 ) over 24 hours on day 1 and cisplatin 50 mg/m ( 2 ) on day 2 , repeated every 3 weeks ) or paclitaxel plus carboplatin ( TC ; paclitaxel 175 mg/m ( 2 ) over 3 hours and carboplatin area under curve 5 mg/mL/min on day 1 , repeated every 3 weeks ) .