We examined changes in urine protein : creatinine ( UPCR ) and urine albumin : creatinine ( UACR ) ratios in 245 ART-naive participants in A5202 randomized in a substudy to blinded NRTI ( abacavir/lamivudine , ABC/3TC , n = 124 or TDF/emtricitabine , TDF/FTC , n = 121 ) with open-label protease inhibitor ( PI ) atazanavir/ritonavir or nonnucleoside reverse transcriptase inhibitor ( NNRTI ) efavirenz .