The primary outcomes were the changes from baseline to week 80 in scores on the 11-item cognitive subscale of the Alzheimer 's Disease Assessment Scale ( ADAS-cog11 ; range , 0 to 70 , with higher scores indicating greater cognitive impairment ) and the Alzheimer 's Disease Cooperative Study-Activities of Daily Living scale ( ADCS-ADL ; range , 0 to 78 , with lower scores indicating worse functioning ) .