Compared with twice-daily NPH , once-daily glargine treatment resulted in significantly lower adjusted odds ratios ( OR ) for all daytime hypoglycemia ( OR 0.74 ; p = 0.030 ) and any severe event ( OR 0.64 ; p = 0.035 ) , representing a 26 % and 36 % reduction in the odds of daytime and severe hypoglycemia , respectively .