Exclusion criteria included the use of any PD medication within 60 days , the use of any symptomatic PD medication for more than 90 days , atypical or drug-induced parkinsonism , a Unified Parkinson 's Disease Rating Scale ( UPDRS ) rest tremor score of 3 or greater for any limb , a Mini-Mental State Examination score of 25 or less , a history of stroke , the use of certain supplements , and substantial recent exposure to CoQ10 .