Pearl Indices ( 95 % confidence intervals ) for the intention-to-treat population ( cycles 1-6 ) were 4.45 ( 2.34-6 .57 ) for Patch and 4.02 ( 0.50-7 .53 ) for Pill ; excluding laboratory-verified noncompliant participants , Pearl Indices were 2.82 ( 0.98-4 .67 ) for Patch and 3.80 ( 0.08-7 .52 ) for Pill ( differences not statistically significant ) .