Both agents suppressed PTH effectively ( -52 % with paricalcitol and -46 % with calcitriol ; P = 0.17 ) , although the paricalcitol group reached a 40 % reduction in PTH sooner at a median 8 weeks ( interquartile range [ IQR ] , 4 , 12 ) versus 12 weeks ( IQR , 8 , 18 ; P = 0.02 ) and had a lower pill burden of 240 ( IQR , 180 , 298 ) versus 292 ( IQR , 231 , 405 ; P = 0.01 ) .