Drug targeting nebulization delivered a large amount of drug into the peripheral part of the lung independent of the modality ( outer-to-inner deposition ratio of 1.24 0.21 vs. 1.22 0.14 for central and peripheral modalities , respectively ) , but there was no difference in lung deposition ( whole-body deposition , 83.3 6.5 % vs. 82.8 7.3 % , P = .86 ) or regional deposition ( P = .77 ) between both modalities .