Mean A1C decreased from 8.0 0.9 % ( 64 10 mmol/mol ) to 7.6 0.9 % ( 60 10 mmol/mol ) ( P < 0.0001 ) , fasting glucose from 9.0 4.3 to 7.0 3.2 mmol/L ( P = 0.008 ) , symptomatic hypoglycemia ( < 3.0 mmol/L ) from 0.12 to 0.04 events per patient per day ( P = 0.0004 ) , and daily insulin dose from 54.7 20.4 to 45.8 18.8 units/day ( P < 0.0001 ) .