Compared with a mean yield of 0.49 % ( 0.13 % ) ( controls ) , yields were 1.07 % ( 0.20 % ) ( OR = 2.20 , 95 % CI = 1.26 , 3.84 , p = 0.006 ) and 1.16 % ( 0.22 % ) ( OR = 2.38 , 95 % CI = 1.38 , 4.13 , p = 0.002 ) for COPD-PS and COPD-PS + copd-6 study arms , respectively .