Mean measured blood loss was 341.5 ml ( standard deviation [ SD ] 206.2 ) and 304.2 ml ( SD 190.8 , p = 0.002 ) at 2 h and 484.7 ml ( SD 213.3 ) and 432.8 ml ( SD 203.5 , p < 0.001 ) at 24 h in the misoprostol and oxytocin groups , respectively .