Compared with that before treatment , ACTH in Chinese herb group and corticoid groups began to decrease obviously on day 3 ( 29.903.31 ng/L vs. 33.103.31 ng/L , 28.202.45 ng/L vs. 33.303.84 ng/L , both P < 0.01 ) , while in control group declined ACTH appeared later ( on day 14 ) compared with before treatment ( 29.405.63 ng/L vs. 33.504.89 ng/L , P < 0.05 ) .