The pressure flow studies demonstrated that silodosin had significantly enlarged the bladder capacity when the first non-voiding contraction was seen at 3 and 12 months ( 3M : 127.1 74.8 vs. 118.2 83.9 mL , p = 0.001 ; 12M : 123.7 79.3 vs. 100.3 73.4 mL , p = 0.01 ) ; however , there were no improvements in the bladder outlet obstruction index ( BOOI ) or urinary flow .