The objectives of this analysis were : ( 1 ) to evaluate the pharmacokinetics of pregabalin controlled-release ( CR ) administered with food relative to the pregabalin IR formulation administered fasted ; ( 2 ) to evaluate the pharmacokinetics of a two-tablet dose of pregabalin CR compared with the equivalent one-tablet dose of pregabalin CR ; and ( 3 ) to determine the safety and tolerability of multiple-dose administration of pregabalin CR and IR .