In a double-blind trial , patients were randomly assigned to echium oil ( intervention ( I ) group ; 7.5 ml bis in die ( b.i.d. ) , 235 mg/ml - linolenic acid ( ALA ) + 95 mg/ml stearidonic acid ( SDA ) + 79 mg/ml - linolenic acid ( GLA ) ) or n-3 FA deficient sunflower oil high oleic ( control ( C ) group ; 7.5 ml b.i.d. ) additional to standard nutritional support during treatment .