In patients treated with 2 GAD-alum doses , stimulated C-peptide area under the curve had decreased significantly less ( 9 m : p < 0.037 ; 15m : p < 0.032 ; 21m : p < 0.003 and 30 m : p < 0.004 ) , and a larger proportion of these patients were also able to achieve a peak stimulated C-peptide > 0.2 nmol/L ( p < 0.05 ) , as compared with placebo .