Patients were subdivided regarding age ( < 64 versus > 70years , 14 % versus 35 % female ) , euroSCORE ( < 3 versus > 4 , 14 % versus 29 % female ) and sRAGE changes between sternotomy and end of the operation ( < 30 % versus > 45 % , 33 % versus 33 % female ) and subsequently analysed with respect of postoperative outcome parameters .