Major bleeding was similar with ticagrelor vs clopidogrel among patients with ( 25.7 % vs 25.5 % , HR 1.02 [ 0.90-1 .15 ] ) and without ( 7.3 % vs 6.4 % , HR 1.14 [ 0.98-1 .33 ] , Pinteraction = .24 ) extensive CAD .