At the second interim analysis of overall survival ( 58 % maturity ) , overall survival did not significantly differ between the groups ( HR 088 [ 95 % CI 064-121 ] ; p = 044 ) ; similar findings were noted for patients with mutated BRCA ( HR 073 [ 045-117 ] ; p = 019 ) and wild-type BRCA ( HR 099 [ 063-155 ] ; p = 096 ) .