Acute infusion of capsaicin-contained red pepper sauce significantly increased pressure wave amplitudes of distal esophagus during slow ( p = 0.003 ) and rapid air injections ( p = 0.01 ) , but repeated infusion of capsaicin-contained red pepper sauce significantly decreased pressure wave amplitude of distal esophagus during slow ( p = 0.0005 ) and rapid air injections ( p = 0.003 ) .