In additive genetic models , we identified nonsignificant associations with AMD for T280M ( RR , 0.87 ; P = .07 ) and 3 other SNPs , rs2853707 ( RR , 0.88 ; P = .07 ) , rs12636547 ( RR , 0.85 ; P = .10 ) , and rs1877563 ( RR , 0.84 ; P = .06 ) , 1 of which , rs2853707 , is positioned in the CX3CR1 promoter region and was associated with neovascular AMD ( RR , 0.75 ; P = .03 ) .