Transfusion was associated with an increase in all-cause mortality among patients with < 6 % and 6 % -20 % predicted risk of death ( odds ratio [ OR ] 5.40 , 95 % CI 4.08-7 .13 , p < 0.0001 , and OR 2.31 , 95 % CI 1.96-2 .73 , p < 0.0001 , respectively ) , but with a decrease in all-cause mortality in patients with > 50 % predicted risk of death ( OR 0.59 , 95 % CI 0.47-0 .74 , p < 0.0001 ) .