In both modules , the number of FUs per year was significantly reduced ( Module A HM-ON 0.29 0.6 FUs/year vs HM-OFF 0.53 0.5 FUs/year ; p b 0.001 ; Module B HM-ON 0.87 0.25 vs HM-OFF 1.73 0.53 FU/year , p b 0.001 ) .