In multivariate analysis , age 40 years ( OR 12.4 95 % CI 1.9-171 , p = 0.003 ) , genotype 2-3 versus 1-4 ( OR 8.1 95 % CI 8.1 1.2-97 , p = 0.002 ) and relapser status at first treatment ( OR 32.9 95 % CI 3.2-278 , p < 0.0001 ) were significantly associated with SVR .