Cinitapride significantly reduced the overall severity of postprandial fullness , early satiation , and bloating ( 4.33.9 vs. 17.86.6 , P < 0.001 ) ; and it was superior to the effects of domperidone ( 5.44.9 vs. 18.46.9 , P < 0.001 ; P = 0.021 between groups ) .