In response to Mhyo stimulation , numbers of IFN secreting PBMC and levels of interleukin 8 ( IL8 ) and IL10 in PBMC supernatants were significantly higher in SF-pCD pigs , as were Mhyo antibody levels in sera , and levels of IL1 , IL8 and IL12 in supernatants of PMA/Iono stimulated PBMC .