The relative risk of hospitalization for heart failure with saxagliptin was similar ( P for interaction = 0.43 ) in patients with eGFR > 50 mL/min/1 .73 m ( 2 ) ( HR 1.23 [ 95 % CI 0.99-1 .55 ] ) , eGFR 30-50 mL/min/1 .73 m ( 2 ) ( HR 1.46 [ 95 % CI 1.07-2 .00 ] ) , and in patients with eGFR < 30 ( HR 0.94 [ 95 % CI 0.52-1 .71 ] ) .