The doses of surfactant administered ( 1.10.3 vs. 1.50.5 , P = 0.027 ) , Lowest FiO2 ( 0.290.05 vs. 0.390.06 , P = 0.000 ) , time to lowest FiO2 [ ( 10318 ) vs. ( 368138 ) min , P = 0.000 ] and O2 dependency [ ( 7.61.0 ) vs. ( 8.81.3 ) days , P = 0.021 ] in LRM group were lower than that in control group ( all P < 0.05 ) .