At month 3 , mean improvement in central retinal thickness ( CRT ) was 90.6 m ( laser ) ( -18.65 ; 199.8 ) , 379.5 m ( IVR ) ( 204.2 ; -554.8 ) , and 248 m ( 167.2 ; -328.8 ) ( combination ) ( IVR versus laser p = 0.005 , laser versus combination p = 0.02 ) .