The week 52 model-adjusted difference in change of glycated haemoglobin ( primary endpoint ) for albiglutide versus placebo was -0.87 [ 95 % confidence interval ( CI ) -1.07 , -0.68 ] % - units ( p < 0.001 ) , and for albiglutide versus pioglitazone it was 0.25 ( 95 % CI 0.10 , 0.40 ) % - units ; therefore , not non-inferior .