ILI and DSE participants lost ( mean SE ) 4.7 % 0.2 % and 2.1 0.2 % of initial weight , respectively ( P < 0.001 ) at year 8 ; 50.3 % and 35.7 % , respectively , lost 5 % ( P < 0.001 ) , and 26.9 % and 17.2 % , respectively , lost 10 % ( P < 0.001 ) .