In those with moderate hyperkalemia , the reduction was 0.87 ( 95 % CI , 0.60-1 .14 ) mEq/L for the 8.4 g twice daily starting-dose group , 0.97 ( 95 % CI , 0.70-1 .23 ) mEq/L for the 12.6 g twice daily starting-dose group , and 0.92 ( 95 % CI , 0.67-1 .17 ) mEq/L for the 16.8 g twice daily starting-dose group ( P < .001 for all changes vs baseline by hyperkalemia starting-dose groups within strata ) .