Nine children received insulin with dose escalations from 2.5 to 7.5 mg ( n = 3 ) , 2.5 to 22.5 mg ( n = 3 ) , or 7.5 to 67.5 mg ( n = 3 ) after 6 months ; 6 children only received doses of 22.5 mg ( n = 3 ) or 67.5 mg ( n = 3 ) .