At 48 weeks , the percentage of decline in total hip BMD was smaller in the vitamin D3 plus calcium group than in the placebo group : Medians were -1.36 % ( interquartile range [ IQR ] , -3.43 % to 0.50 % ) and -3.22 % ( IQR , -5.56 % to -0.88 % ) , respectively ( P = 0.004 ) .