With median follow-up of 95 months , biopsy-proven cute rejection incidence was similar in the three groups ( 8/43 , 14/43 , and 12/42 , P = 0.34 ) , but biopsy-proven chronic allograft injury incidence was significantly higher in group B ( 19/43 ) in comparison with groups A ( 9/43 ) and C ( 7/42 ) combined ( P = 0.0008 ) .