Compared with the control group , cystatin C at 48 hours after treatment was significantly decreased , while CCr was significantly increased in treatment group ( cystatin C : 0.850.81 mg/L vs. 1.010.91 mg/L , t = 2.562 , P = 0.017 ; CCr : 0.930.64 mL/s vs. 0.690.40 mL/s , t = 2.155 , P = 0.033 ) .