Levels of interleukin ( IL ) -1 , IL-5 , IL-6 , IL-10 , IL-17 , interferon ( IFN ) - and tumor necrosis factor ( TNF ) - were measured from whole-blood assays stimulated with innate agonists to Toll-like receptor ( TLR ) -2 , -4 or -7 / 8 , or purified protein derivative ( PPD ) .