Patients were randomised to three courses of 5-FU/l-LV ( 5-FU 500 mg/m ( 2 ) , l-LV 250 mg/m ( 2 ) on days 1 , 8 , 15 , 22 , 29 , 36 every 8 weeks ) or five courses of UFT/LV ( UFT 300 mg m ( -2 ) day ( -1 ) , LV 75 mg/day on days 1-28 every 5 weeks ) .