The maximum exercise-induced FEV1 fall was 27.9 1.4 % during the run-in period , 8.1 1.2 % ( 70.3 4.1 % bronchoprotection ) after the first salmeterol dose , and 22.8 3.2 % ( 18.9 11.5 % bronchoprotection ) after 2 weeks of salmeterol ( P = 0.0001 ) .