Adjusted DIT was faster in patients who arrived by ambulance ( 7.2 minutes ; 95 % confidence interval , 4.1-10 .2 ) , had severe strokes ( 1.0 minute per +5 - point National Institutes of Health Stroke Scale ; 95 % confidence interval , 0.1-2 .0 ) , and presented in the postintervention period ( 4.9 minutes ; 95 % confidence interval , 2.3-7 .4 ) .