Lactate clearance rate in modified surviving sepsis bundle group was significantly higher than that of standard surviving sepsis bundle group [ 6 hours : ( 18.28.3 ) % vs. ( 10.87.5 ) % , t = -6.036 , P = 0.001 ; 12 hours : ( 22.67.3 ) % vs. ( 12.48.1 ) % , t = -4.536 , P = 0.001 ; 24 hours : ( 27.85.6 ) % vs. ( 16.49.5 ) % , t = -5.882 , P = 0.000 ] .