A total of 165 evaluable patients were randomly assigned at a 2:1 ratio to receive SC-PEG at 2,100 ( SC-PEG2100 ; n = 69 ) or 2,500 IU/m ( 2 ) ( SC-PEG2500 ; n = 42 ) versus SS-PEG 2,500 IU/m ( 2 ) ( SS-PEG2500 ; n = 54 ) as part of an otherwise identical chemotherapy regimen .