Comprehensive care reduced ( per 100 child-years ) serious illnesses ( 16 vs 44 for usual care ; RR , 0.33 [ 95 % CI , 0.17-0 .66 ] ) , emergency department visits ( 90 vs 190 ; RR , 0.48 [ 95 % CI , 0.34-0 .67 ] ) , hospitalizations ( 69 vs 131 ; RR , 0.51 [ 95 % CI , 0.33-0 .77 ] ) , pediatric ICU admissions ( 9 vs 26 ; RR , 0.35 [ 95 % CI , 0.18-0 .70 ] ) , and number of days in a hospital ( 276 vs 635 ; RR , 0.36 [ 95 % CI , 0.19-0 .67 ] ) .