Mean weight loss was significantly ( P < .001 ) greater in the LI arm versus the comparison arm ( 4.3 v 0.6 kg or 5.3 % v 0.7 % at 6 months and 3.1 v 0.3 kg or 3.6 % v 0.4 % at 24 months ) and occurred consistently across strata ( BMI 24 to < 30 v 30 kg/m ( 2 ) ; prior v no prior adjuvant chemotherapy ) .