Adjusted hazard ratios for modified Agatston score strata of 1 to 10 , 11 to 100 , 101 to 400 , and > 400 were 3.39 ( 95 % confidence interval [ CI ] , 1.20-9 .59 ) , 6.52 ( 95 % CI , 2.73-15 .60 ) , 6.58 ( 95 % CI , 2.75-15 .78 ) , and 12.58 ( 95 % CI , 5.42-29 .16 ) , respectively .