More patients achieved at least a 30 % reduction in ADHD symptom severity in the medication groups ( 60 mg : 30 of 40 participants [ 75.0 % ] ; odds ratio [ OR ] = 5.23 ; 95 % CI , 1.98-13 .85 ; P < .001 ; and 80 mg : 25 of 43 participants [ 58.1 % ] ; OR = 2.27 ; 95 % CI , 0.94-5 .49 ; P = .07 ) compared with placebo ( 17 of 43 participants [ 39.5 % ] ) .