The combined group was found to have the longest operation time ( p < 0.02 ; p < 0.01 , respectively ) , larger blood loss ( p < 0.006 ; p < 0.005 , respectively ) , longer hospital stay ( p < 0.01 ; p < 0.003 , respectively ) and higher hospitalisation costs ( p < 0.004 ; p < 0.001 , respectively ) .