Patients with first-year nadir testosterone consistently > 0.7 nmol/L had significantly higher risks of dying as a result of disease ( 0.7 to 1.7 nmol/L : hazard ratio [ HR ] , 2.08 ; 95 % CI , 1.28 to 3.38 ; > 1.7 nmol/L : HR , 2.93 ; 95 % CI , 0.70 to 12.30 ) and developing hormone resistance ( 0.7 to 1.7 nmol/L : HR , 1.62 ; 95 % CI , 1.20 to 2.18 ; 1.7 nmol/L : HR , 1.90 ; 95 % CI , 0.77 to 4.70 ) .