Increased levels of MTXGlu2 ( = -0.20 , P = 0.005 ) , MTXGlu3 ( = -0.31 , P < 0.001 ) , MTXGlu4 ( = -0.33 , P < 0.001 ) after treatment , MTXGlu5 ( = -0.39 , P < 0.001 ) , and total MTXGlu ( = -0.29 , P < 0.001 ) were associated with decreased levels of HBA1c .