50 patients in the 6-week group and 51 in the 12-week group had adverse events , the most common being death ( 14 [ 8 % ] in the 6-week group vs 12 [ 7 % ] in the 12-week group ) , antibiotic intolerance ( 12 [ 7 % ] vs 9 [ 5 % ] ) , cardiorespiratory failure ( 7 [ 4 % ] vs 12 [ 7 % ] ) , and neurological complications ( 7 [ 4 % ] vs 3 [ 2 % ] ) .