Remote ischaemic pre-conditioning in non-diabetic patients evoked a 41 % decrease in the troponin I concentration area under curve ( 514 ng/ml 72 h 600 vs. 302 190 , P = 0.001 ) but no change ( 404 ng/ml 72 h 224 vs. 471 383 , P = 0.62 ) in sulphonylurea-treated diabetics .