Between-group differences in the changes in the ADAS-cog14 score were -1.7 points in patients with mild Alzheimer 's disease ( 95 % CI , -3.5 to 0.1 ; P = 0.06 ) and -1.5 in patients with moderate Alzheimer 's disease ( 95 % CI , -4.1 to 1.1 ; P = 0.26 ) .