The mean dosages ( sd ) were significantly different between the ADRB2 genotypes [ Arg16Arg 357 g ( 326 ) , Arg16Gly 776 g ( 449 ) , Gly16Gly 600 g ( 443 ) , P = 0.036 ; Gln27Gln 356 g ( 254 ) , Gln27Glu 639 g ( 354 ) , Glu27Glu 577 g ( 388 ) , P = 0.007 ] .