A total of 226 patients with 293 intermediate coronary artery lesions ( stenosis of 40 % -70 % ) confirmed by coronary angiography were randomized into 3 groups to undergo PCI for a minimal lumen cross sectional area ( MLA ) < 4 mm ( 2 ) ( IVUS group , 98 lesions ) or for a FFR < 0.80 ( FFR group , 101 lesions ) , or to receive standard medical treatment ( medication group , 94 lesions ) .