The most frequently reported acute radiation-related toxicities at 14 days were lack of appetite ( 201 [ 56 % ] of 358 assessable patients who received 8 Gy vs 229 [ 66 % ] of 349 assessable patients who received 20 Gy ; p = 0011 ) and diarrhoea ( 81 [ 23 % ] of 357 vs 108 [ 31 % ] of 349 ; p = 0018 ) .