Fifty-two subjects were supplemented and followed for 12 months , 17 of them were in intervention Group 1 ( 20 mg/day lutein and 2 mg/day zeaxanthin ) ; 21 in Group 2 ( 10 mg/day meso-zeaxanthin , 10 mg/day lutein , and 2 mg/day zeaxanthin ) ; and 14 in Group 3 ( 17 mg/day meso-zeaxanthin , 3 mg/day lutein , and 2 mg/day zeaxanthin ) .