Tafenoquine 300 mg and 600 mg had better efficacy than chloroquine alone ( treatment differences 517 % [ 95 % CI 35-69 ] , p < 00001 , with tafenoquine 300 mg and 545 % [ 38-71 ] , p < 00001 , with tafenoquine 600 mg ) , as did primaquine ( treatment difference 399 % [ 21-59 ] , p = 00004 ) .