The authors evaluated teh following : daily number of hot flushes and Kupperman Index at baseline and after one and three months ; serum total , high-density lipoprotein ( HDL ) and low-density lipoprotein ( LDL ) cholesterol , triglycerides , prothrombin time ( PT ) , partial thromboplastin time ( PTT ) , fibrinogen , and antithrombin III ( ATIII ) at baseline and after three and six months .