Non-high-density lipoprotein cholesterol ( non-HDL-C ) , total cholesterol-to-HDL-C ratio , very low-density lipoprotein cholesterol , remnant-like particle cholesterol , apolipoprotein CIII , lipoprotein-associated phospholipase A2 , and arachidonic acid were significantly lowered ( P < .05 at each OM3-FFA dosage vs OO ) ; and plasma eicosapentaenoic acid and docosahexaenoic acid were significantly elevated ( P < .001 at each OM3-FFA dosage vs OO ) .