Baseline BMI was a statistically significant predictor of RFS ( adjusted hazard ratio [ HR ] for each five-unit increase in BMI = 1.08 , 95 % confidence interval [ CI ] = 1.02 to 1.14 , P = .01 ) and OS ( adjusted HR = 1.08 , 95 % CI = 1.01 to 1.14 , P = .02 ) BMI and molecular phenotypes were independent prognostic factors for RFS , with no statistically significant interactions detected .