For 26 % of the participants with both these characteristics , SRT resulted in 55 % fewer ranibizumab injections ( 2.08 vs. 4.60 ; P = 0.0002 ) , a mean visual acuity change that was 5.33 letters superior to sham ( +2.18 vs. -3.15 letters ; P = 0.0284 ) , and a 71.1-m greater reduction in mean central subfield thickness ( -122.6 vs. -51.5 m ; P = 0.027 ) .