After 8-week treatment , there was statistical difference in the overall fatality rate ( 15.63 % vs 34.15 % ) , the fatality rate in the mid-term ( 25.0 % vs 64.7 % ) , TBIL at week 8 ( 64.54 + / - 79.75 ) , AST [ at week 2 : ( 178.97 + / - 44.24 ) U/L vs ( 288.48 + / - 58.49 ) U/L ; at week 4 : ( 61.65 + / - 27.36 ) U/L vs ( 171.12 + / - 89.11 ) U/L ] and PTA [ at week 4 : ( 58.30 + / - 15.29 ) vs ( 42.56 + / - 15.27 ) ; at week 6 : ( 60.77 + / - 20.40 ) vs ( 43.08 + / - 12.79 ) ] ( all P < 0.05 ) .