In the first study of the Efficacy and Safety of 6-day Oral Tedizolid in Acute Bacterial Skin and Skin Structure Infections vs. 10-day Oral Linezolid Therapy ( ESTABLISH-1 ) , the sizes of ABSSSI lesions were evaluated with the two methodologies of : ( 1 ) Digital planimetry ( DP ) of photographed lesions , and ( 2 ) a ruler technique ( RT ) with measurement of the longest head-to-toe length and greatest perpendicular width of lesions , to compare the respective response rates of lesions to the two antimicrobial regimens in the study .