HN at increased settings performed better than FM in decreasing inspiratory effort measured by pressure-time product of transdiaphragmatic pressure ( PTPdi ) / breath ( 10.79.9 versus 17.011.0 cmH2Os ) , and PTPdi/min ( 12896 versus 20481 cmH2Os/min ) , and PTPdi/L ( 12.69.9 versus 30.216.8 cmH2Os/L ) .