CoA plus statin was associated with significant reductions in TC ( -9.1 % vs -3.1 % ; p = 0.0033 ) , LDL-C ( -9.9 % vs 0.1 % ; p = 0.003 ) , and non - high-density lipoprotein cholesterol ( -13.5 % vs -5.7 % ; p = 0.0039 ) .