Similar results for good MRD ( 3 < MRD < 5 ) were found in closed ( 54.5 % , 12/22 ) and open ( 54.5 % , 12/22 ) methods , while 40.9 % ( 9/22 ) and 45.5 % ( 10/22 ) of cases were attributed to the under correction group in the closed and open methods , respectively .