Subjects were treated with ronacaleret 100mg ( n = 16 ) , 200mg ( n = 38 ) , 300mg ( n = 35 ) , or 400mg ( n = 32 ) once daily , alendronate 70mg ( n = 17 ) once weekly , or matching placebo ( n = 33 ) for 10-12months ; BMD was measured after discontinuation of ronacaleret or alendronate treatment .