Patients were randomly assigned ( 1:1 ) to either androgen deprivation therapy ( ADT ; goserelin 108 mg every 3 months for 3 years ) plus four cycles of docetaxel on day 2 at a dose of 70 mg/m ( 2 ) and estramustine 10 mg/kg per day on days 1-5 , every 3 weeks , or ADT only .