There were no significant differences found in the levels of IL-6 and CRP between RIPC and control groups during the whole study Unexpectedly significant excess concentrations of IL-8 at 24 h were found when RIPC applied during sevoflurane anesthesia : 12.3 ( 10.6 , 14.4 ) pg/mL in RIPCsevo group vs 6.2 ( 4.8 , 11.1 ) pg/ml in CONTROLsevo group ( p = 0.02 ) .