The advantage was detected since the early 3 ( rd ) day evaluation ( 37.3 % vs 6.4 % for the rSK and active control groups , respectively ; P < 0.001 ) and was kept even at the late 10 ( th ) day assessment ( 83.6 % vs 58.2 % for rSK and phenylephrine , respectively ; P < 0.001 ) .