Using the prior 6-month cumulative dose of VDRA , we also found that a cumulative VDRA dose of less than 45 mcg ( OR , 1.05 ; 95 % CI , 0.92-1 .19 ) or greater than 45 mcg ( OR , 1.15 ; 95 % CI , 0.96-1 .36 ) was not associated with the IRH risk .