The last observation carried forward for the count of non-inflammatory lesions changed from 37.5 17.8 to 37.7 17.8 in the minocycline group and from 36.9 15.5 to 33.4 19.3 in the lymecycline group ( no significant changes ) ; corresponding changes in inflammatory lesions were from 19.4 12.4 to 12.2 10.0 in the minocycline group and from 20.1 11.3 to 12.6 8.4 in lymecycline group ( P < 0.05 comparing baseline vs. final in both groups ) .