Twenty-seven sedentary men ( 52.1 9.5 years , body mass index 30.4 3.8 kg/m ( 2 ) , estimated glomerular filtration rate ( eGFR ) 27.5 11.6 mL/min ) were randomly assigned to a centre-based exercise group ( n = 10 ) , home-based exercise group ( n = 8 ) or control group ( n = 9 ) .