3 months after radiotherapy , 73 ( 22 % ) patients in the standard fractionation group and 75 ( 23 % ) patients in the hypofractionation group reported grade 2 or worse genitourinary toxicity ; grade 2 or worse gastrointestinal toxicity was noted in 43 ( 13 % ) patients in the standard fractionation group and in 42 ( 13 % ) in the hypofractionation group .