At 6 months , there were significantly greater improvements in anxiety ( F ( 2,198 ) = 5.612 , P = 0.004 ) , depression ( F ( 1.8,176.1 ) = 10.697 , P0 .001 ) and dyspnoea ( F ( 2,198 ) = 18.170 , P0 .001 ) in the CM group .