On the basis of intention-to-treat analyses , no significant group differences were observed in percentage of patients opting for a direct BLM ( 14.6 % for the RGCT group vs 9.2 % for the control group ; odds ratio ( OR ) 2.31 ; confidence interval ( CI ) 0.92-5 .81 ; P = 0.08 ) or for a delayed CPM ( 4.5 % for the RGCT group vs 5.7 % for the control group ; OR 0.89 ; CI 0.27-2 .90 ; P = 0.84 ) .