Mean estimated pain scores on VAS ( SC : 69.0 , MA : 66.4 and EA : 68.5 ) , adjusted for : treatment , age , education , and time from baseline , with no interactions did not differ between the groups ( SC vs MA : mean difference 2.6 , 95 % confidence interval [ CI ] -1.7 -6.9 and SC vs EA : mean difference 0.6 [ 95 % CI ] -3.6 -4.8 ) .