Furthermore , the mean dose of misoprostol required to achieve induction of labor and the mean duration of oxytocin augmentation when indicated were significantly less in the vaginal group than in the oral group ( 2.5 1.3 vs. 2.0 1.1 ; mean difference : 0.50 , 95 % CI 0.10-0 .90 ; p = 0.02 and 4.6 3.2 vs. 3.4 3.1 ; mean difference : 1.20 , 95 % CI 0.15-0 .23 ; p = 0.03 respectively ) .