Squeeze bottle : SNOT-22 49.5 versus 23.6 , treatment effect 25.9 ( 95 % CI , 20.3-31 .6 ) , POSE 18.6 versus 9.2 , treatment effect 9.3 , ( 95 % CI 6.7-12 .0 ) , and NSS 9.0 versus 5.7 , treatment effect 3.3 ( 95 % CI , 2.3-4 .3 ) pre - and postoperatively , respectively ( all p < 0.0001 ) .