Within the MRD intermediate-risk group , iAMP21 cases ( n = 27 ) had a worse 8-year EFS ( 56 11 % vs. 78 2 % , p = 0.0077 ) and CIR ( 44 11 % vs. 20 2 % , p = 0.003 ) with 6/10 relapses occurring after 2 years .