In the European Union study , the duration of pain-free time after 9 months was also longer in the afamelanotide group than in the placebo group ( median , 6.0 hours vs. 0.8 hours ; P = 0.005 ) , and the number of phototoxic reactions was lower in the the afamelanotide group ( 77 vs. 146 , P = 0.04 ) .