Planned assessments included Montgomery-Asberg Depression Rating Scale ( MADRS ) , Young Mania Rating Scale ( YMRS ) , Clinical Global Impressions-Severity of Illness scale ( CGI-S ) , Clinical Global Impressions-Improvement scale ( CGI-I ) , Hamilton Depression scale ( HAMD ) , Hamilton Anxiety scale ( HAMA ) , and Treatment Emergent Symptom Scale ( TESS ) .