By excluding the advanced patients from analysis , there were significant differences in Unified Parkinson 's Disease Rating Scale V2 ( P = 0.004 ) and V3 ( P = 0.040 ) , Hamilton Depression Rating Scale V1 ( P = 0.014 ) and V2 ( P = 0.047 ) , Neuropsychiatry Inventory V1 ( P = 0.002 ) and V2 ( P < 0.001 ) and Behavior Pathology in Alzheimer 's Disease Rating Scale V2 ( P = 0.025 ) in favor of sarcosine .