The results showed a significant difference in remission rate between risperidone monotherapy and risperidone plus sodium valproate at the 1st , 2nd and the 3rd week ( p = 0.012 , 0.023 , 0.027 respectively ) , It means the remission rate in risperidone plus valproate group was higher in the first three weeks , but at the end of the seventh week , the difference was not statistically significant .