Compared with those with neither ( n = 972 ) , patients with VMT or VMA were younger ( mean standard error , 75.5 0.6 vs. 79.7 0.24 years ; P < 0.0001 ) and more likely to be male ( 52.4 % vs. 36.2 % ; P = 0.0003 ) , to be cigarette smokers ( 68.5 % vs. 55.3 % ; P = 0.003 ) , and to have subretinal fluid on OCT ( 86.7 % vs. 81.0 % ; P = 0.047 ) .