Patients are evaluated with an extensive battery of tests assessing clinical and sociodemographic characteristics ( Positive and Negative Syndrome Scale , State-Trait Anxiety Inventory , Liebowitz Social Anxiety Scale , Hamilton Rating Scale for Depression , Scale to Assess Unawareness of Mental Disorders , Strauss and Carpenter Prognostic Scale , Global Assessment of Functioning Scale , Morisky Green Adherence Scale , Functioning Assessment Short Test , World Health Organization Quality of Life instrument WHOQOL-BREF ( an abbreviated version of the WHOQOL-100 ) , and EuroQoL questionnaire ) , and brain-derived neurotrophic factor levels are measured in peripheral blood at baseline and at 6 months .