After single-dose intravenous administration of 0.25 , 0.50 , and 0.75 mg/kg of pilsicainide hydrochloride , mean Cmax was 0.34 ( 0.11 ) , 0.54 ( 0.15 ) , and 1.05 ( 0.19 ) g/mL , respectively ; AUC0-24 was 0.76 ( 0.12 ) , 1.61 ( 0.37 ) , and 2.61 ( 0.46 ) h g/mL ; and AUC0 - was 0.79 ( 0.13 ) , 1.71 ( 0.46 ) , and 2.72 ( 0.50 ) h g/mL .