There were no between-group differences in the Psychosocial Adjustment to Illness State-Self Report ( PAIS-SR ) or in the EuroQoL Group Five-Dimension Self-Report Index Questionnaire ( EQ-5D ) from baseline to week 60 ; however , PAIS-SR scores improved significantly over this period in the G + 3 group ( p = 0.0016 ) and EQ-5D scores worsened significantly in the PM-2 group ( p = 0.02 ) .