The serum level of lipids , left ventricular end-diastolic diameter ( LVEDD ) , left ventricular end-systolic diameter ( LVESD ) , interventricular septum thickness ( IVST ) , left ventricular posterior wall thickness ( LVPWT ) , fractional shortening rate ( FS ) , left ventricular ejection fraction ( LVEF ) and E/A ratio were measured before , 6 month , 12 month and 2 years after treatment .