The proportion of neonates with detectable B. breve increased significantly post intervention : Placebo : [ S1 :2 / 66 ( 3 % ) , S2 : 25/66 ( 38 % ) , p < 0.001 ] Probiotic : [ S1 : 29/74 ( 40 % ) , S2 : 67/74 ( 91 % ) , p < 0.001 ] .