66 chemonave patients with stage IIIB/IV NSCLC received oral vinorelbine ( first cycle 60 mg/m ( 2 ) , subsequent cycles : 80 mg/m ( 2 ) in the absence of any hematological toxicity grade 3 in cycle 1 ) once daily on days 1 and 8 of each cycle and cisplatin ( 80 mg/m ( 2 ) i.v. ) on day 1 of each cycle ( q3w ) .