Pneumonia was radiologically confirmed by concordant reading in 277 ( 33.8 % ) cases , among whom treatment failure was registered in 25/133 ( 18.8 % ) and 27/144 ( 18.8 % ) participants from the thrice and twice daily doses subgroups , respectively ( risk difference -0.05 % ; 95 % CI : -9.3 % -9.2 % ) .