Of the four 40 cases in the medication , acupuncture , Tongxinluo and acupuncture + Tongxinluo groups , 6 , 7 , 7 and 12 patients were basically cured , 9 , 8 , 9 and 18 experienced marked improvement in their symptoms , 14 , 16 , 15 and 6 were improved , 6 , 5 , 4 and 2 were invalid , 5 , 4 , 5 and 2 got worsened , with the effective rates ( basically cured + improvement ) being 37.5 % , 37.5 % , 40.0 % and 75.0 % , respectively .