There was no significant difference between the study groups in the mean ( SD ) number of ventilator-free days ( 12.69.9 with simvastatin and 11.510.4 with placebo , P = 0.21 ) or days free of nonpulmonary organ failure ( 19.411.1 and 17.811.7 , respectively ; P = 0.11 ) or in mortality at 28 days ( 22.0 % and 26.8 % , respectively ; P = 0.23 ) .