In a comparative analysis , the HR was 1.27 ( 95 % CI = 1.00-1 .61 , p = 0.0497 ) for a 0.5 mg/dl genetically conferred decrease in serum urate , and 1.05 ( 95 % CI = 1.01-1 .10 , p = 0.0133 ) for a 0.5 mg/dl decrease in measured serum urate .