We genotyped 16 candidate SNPs in IL1 , IL2 , IL4 , IL6 , IL8 , IL10 , IL12 ( p40 ) , IFNG , MSR1 , RNASEL , TLR4 , and TNFA and seven tagSNPs in IL10 in 881 prostate cancer cases and 848 controls negative for cancer on an end-of-study biopsy .