Changes from baseline with dapagliflozin 10 mg by day 7 were as follows : -2.29 mmol/L ( 95 % CI -3.71 to -0.87 [ -41.3 mg/dL ; 95 % CI -66.9 to -15.7 ] ) for 24-h daily average blood glucose ; -3.77 mmol/L ( 95 % CI -6.09 to -1.45 [ -63.1 mg/dL ; 95 % CI -111.5 to -14.8 ] ) for mean amplitude of glycemic excursion ; and -16.2 % ( 95 % CI -29.4 to -0.5 ) for mean percent change in total daily insulin dose .