Among HPV-positive women , informed cytology had cross-sectional sensitivity , specificity , PPV and 1-NPV for CIN2 + of 85.6 % ( 95 % confidence interval [ CI ] = 76.6 to 92.1 ) , 65.9 % ( 95 % CI = 63.1 to 68.6 ) , 16.2 % ( 95 % CI = 13.0 to 19.8 ) , and 1.7 ( 95 % CI = 0.9 to 2.8 ) , respectively .