Cases were randomly assigned to 1 of 6 groups receiving the following treatments : ( 1 ) diclofenac ( 0.1 % ) ; ( 2 ) pranoprofen ( 0.1 % ) ; ( 3 ) control , physiological normal saline solution ; ( 4 ) diclofenac ( 0.1 % ) and epinephrine ; ( 5 ) pranoprofen ( 0.1 % ) and epinephrine ; ( 6 ) control , physiological normal saline and epinephrine solutions .