The exercise training was designed with an intensity of 50-70 % heart rate reserve for 3 days a week in 60-minute-long sessions for 9 months , consisting of 30-minute treadmill and 30-minute bike exercises for aerobic group ; upper and lower body exercises with an intensity target of 2 sets and 8-12 repetitions for resistance group ; 30-minute resistance and consecutive 30-minute aerobic exercises for combination group .