There was no significant difference ( treatment change versus no change ) with regards to interval from randomisation to symptomatic metastases - 23 ( 2-62 ) and 22 ( 1-63 ) months respectively ( p = 0.9 ) , as well as interval from randomisation to last follow-up/death - 36 ( 7-63 ) and 37 ( 10-63 ) months respectively ( p = 0.9 ) .