After 7 and 14 days , % COT , % POT , % DPL and % DPI were significantly lower with Na-MFP when compared to 10 % nHAP ( P < 0.01 ) , NovaMin ( P < 0.05 ) and 15 % nHAP ( P < 0.001 ) , the three of which were not significantly different from each other in those four variables .