Consumption of a synbiotic food did not show any significant change regarding the impact of insulin actions in the synbiotic group ; nonetheless , compared to the control food , it resulted in a significant decrease in serum insulin levels ( -0.26 vs. 6.34 IU/mL , P = 0.014 ) and HOMA-IR ( -0.13 vs. 1.13 , P = 0.033 ) , a significant difference in HOMA-B ( 5.30 vs. 34.22 , P = 0.040 ) and a significant rise in QUICKI score ( 0.002 vs. -0.02 , P = 0.022 ) .