The prospective , open , randomized controlled clinical trial ( n = 700 ) will compare Triple Pill-based strategy to usual care among individuals with persistent mild-to-moderate hypertension ( systolic BP > 140 mm Hg and/or diastolic BP > 90 mm Hg , or systolic BP > 130 mm Hg and/or diastolic BP > 80 mm Hg in patients with diabetes or chronic kidney disease ) on no or minimal drug therapy .