The intention-to-treat analysis of the 61 randomised patients showed that the exercise group had a greater increase in peak oxygen uptake ( 3.4 mL/kg/min between-group difference , p = 0.002 ) , carbon monoxide transfer factor ( Tlco ) ( 5.2 % predicted , p = 0.007 ) , 1RM leg press ( 29.5 kg , p < 0.001 ) , chair stand ( 2.1 times p < 0.001 ) , stair run ( 4.3 steps , p = 0.002 ) and total muscle mass ( 1.36 kg , p = 0.012 ) compared with the controls .