The rate and incidence of infections in subjects 60 days old were significantly increased in the TGC compared with the STD group ( rate : 13.5 versus 3.7 infections per 1000 cardiac intensive care unit days , P = 0.01 ; incidence : 13 % versus 4 % , P = 0.02 ) , whereas infections among those > 60 days of age were significantly reduced in the TGC compared with the STD group ( rate : 5.0 versus 14.1 infections per 1000 cardiac intensive care unit days , P = 0.02 ; incidence : 2 % versus 5 % , P = 0.03 ) ; the interaction of treatment group by age subgroup was highly significant ( P = 0.001 ) .