In patients receiving 150 mg and 200 mg sarilumab , neutrophil counts of 0.5 to < 1.0 10 ( 9 ) / liter were observed in 5.1 % and 7.8 % of patients , respectively , while neutrophil counts of < 0.5 10 ( 9 ) / liter were observed in 0.9 % and 0.7 % of patients , respectively ; none of the patients receiving placebo experienced changes in neutrophil counts .