Use of the combination of all four drug classes decreased from discharge to 1 year post-AMI from 74.1 to 37.8 % and was significantly reduced by age 75 years ( odds ratio [ OR ] 0.49 ; 95 % confidence interval [ CI ] 0.29-0 .85 ) and ten or more visits with general practitioners ( GPs ) over 1 year ( OR 0.29 ; 95 % CI 0.17-0 .51 ) .