Stage IIIB/IV untreated/relapsed patients with NS NSCLC received a 3-week cycle of pemetrexed 500 mg/m ( 2 ) and cisplatin 75 mg/m ( 2 ) on day 1 ( arm A ) or oral vinorelbine 80 mg/m ( 2 ) on days 1 and 8 ( first cycle 60 mg/m ( 2 ) ) and cisplatin 80 mg/m ( 2 ) on day 1 ( arm B ) .