All-cause mortality was reduced by EDTA chelation ( 10 % versus 16 % ; hazard ratio , 0.57 ; 95 % CI , 0.36-0 .88 ; P = 0.011 ) , as was the secondary end point ( cardiovascular death , reinfarction , or stroke ; 11 % versus 17 % ; hazard ratio , 0.60 ; 95 % CI , 0.39-0 .91 ; P = 0.017 ) .