A better therapeutic response was found in group A patients , as shown by higher objective response rate ( ORR ) and clinical benefit rate ( CBR ) values in group A versus group B ( ORR , 81.96 % [ 95 % confidence interval ( CI ) , 72.32 % -91.62 % ] vs 59.37 % [ 95 % CI , 47.34 % -71.41 % ] , ( 2 ) = 7.650 , P < .05 ; CBR , 95.08 % [ 95 % CI , 89.66 % -100.00 % ] vs 81.25 % [ 95 % CI , 71.69 % -90.81 % ] , ( 2 ) = 5.659 , P < .05 ) .