When updating information on multivitamin use during the course of follow-up , no associations were observed for major CVD events ( HR : 0.91 ; 95 % CI : 0.82 , 1.02 ) , MI ( HR : 0.89 ; 95 % CI : 0.74 , 1.06 ) , stroke ( HR : 0.91 ; 95 % CI : 0.78 , 1.06 ) , and CVD death ( HR : 0.91 ; 95 % CI : 0.71 , 1.16 ) .