The primary symptomatic improvement outcome did not differ between 65 patients randomized to nortriptyline vs 65 patients randomized to placebo : 15 ( 23 % [ 95 % CI , 14 % -35 % ] ) in the nortriptyline group vs 14 ( 21 % [ 95 % CI , 12 % -34 % ] ) in the placebo group ( P = .86 ) .