We noted no significant difference in cumulative incidence by 120 days after radiotherapy of grade 2 or worse acute genitourinary toxicity ( 578 % [ 95 % CI 529-627 ] in the standard fractionation group vs 605 % ( 558-653 ) in the hypofractionation group ; difference 27 % , 90 % CI -299 to 848 ; odds ratio [ OR ] 112 , 95 % CI 084-149 ; p = 043 ) .