However , the 2.5 mg nicotine film relieved cue-induced craving to a greater degree than the 2 mg nicotine lozenge at 50s ( mean difference : -4.9 , p = 0.014 ) , 3min ( mean difference : -6.7 , p = 0.011 ) , and 5min ( mean difference : -5.6 , p = 0.049 ) post-treatment .