Based on a Cox proportional hazards model , sex was not a significant predictor of recurrence during the first or second maintenance phase ( hazard ratio [ HR ] = 1.233 ; P = .3712 and HR = 1.103 ; P = .8075 , respectively ) , and neither was menopausal status at acute-phase baseline ( HR = 0.941 ; P = .8234 and HR = 0.531 ; P = .2065 , respectively ) .