Rates in patients with HF-PEF were highest in the United States/Canada ( HF hospitalization rate 7.6 per 100 patient-years in I-Preserve ; 8.8 in CHARM-Preserved ) , intermediate in Western Europe ( 4.8 / 100 and 4.7 / 100 ) , and lowest in Eastern Europe/Russia ( 3.3 / 100 and 2.8 / 100 ) .