The phase III North American Intergroup E2496 Trial ( Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin 's Lymphoma ) compared doxorubicin , bleomycin , vinblastine , and dacarbazine ( ABVD ) with mechlorethamine , doxorubicin , vincristine , bleomycin , vinblastine , etoposide , and prednisone ( Stanford V ) .