After 2 weeks of treatment improvements in nasal patency , NSS and NOSE were seen ( NSS 4.13 1.38 vs 1.33 1.93 , p < 0.001 ; NOSE 34 17.97 vs 9 18.21 , p < 0.001 ; nasal patency -26.13 25.25 vs -11.83 11.31 , p < 0.001 ) .