Analysis of secondary outcomes showed a shorter time to first bleeding episode with no prophylaxis in the chemo/alloHSCT group ( hazard ratio , 1.84 ; 95 % confidence interval CI , 1.21-2 .79 ; p = 0.004 ) compared to the autoHSCT group ( hazard ratio , 1.12 ; 95 % CI , 0.85-1 .48 ; p = 0.4 ; interaction p = 0.08 ) .