Significant differences were found in MPCI response for WOMAC pain ( 52 % vs 40 % , P < 0.001 ) , stiffness ( 47 % vs 39 % , P = 0.009 ) and physical function ( 46 % vs 37 % , P = 0.009 ) and in MCII response for WOMAC physical function ( 46 % vs 37 % , P = 0.013 ) .