Significant reduction in the verum compared to the placebo group ( intention-to-treat , population , verum : n = 55 ; placebo : n = 47 ) was found regarding TCS ( P = 0.005 ) , rhinoconjunctivitis total symptom score ( RTSS , P = 0.006 ) , and total rescue medication score ( TRMS , P = 0.002 ) .