In contrast , the number of circulating early differentiation stage EPCs CD45 - / 133 + / 34 + and CD45 - / CD34 + / KDR + raised significantly from 1 h preoperative values ( 57.39.3 ; 57.3 10.7 ) to 1 h postoperative ( ( 74.4 11.4 ; 78.8 16.2 ) , ( p < 0.05 ) ) and 6 h postoperative ( ( 93 16.9 ; 99.7 11.9 ) , ( p < 0.05 ) ) concentrations after coronary angioplasty in the 80mg Atorvastatin medication patients .