The hazard of Global Use of Strategies to Open Occluded Coronary Arteries bleeding with vorapaxar was not significantly different without clopidogrel ( HR 1.33 ; 95 % CI 0.81-2 .20 ) or with clopidogrel ( HR 1.09 ; 95 % CI 0.76-1 .56 ) ( interaction ; P = .53 ) .