After treatment with aspirin , the GMP-140 levels presented a clearly defined downward trend in the immediate postoperative period ( 3mg/kg/day aspirin : 18.303.42 vs. 13.371.80 , p < 0.05 ; 5mg/kg/day aspirin : 18.303.42 vs. 13.411.60 , p < 0.05 ) , but no obvious difference was observed considering the GMP-140 levels in the 4 days after occlusion ( all p > 0.05 ) .