The percentage of time with BIS40-60 was greater in the auto group ( 87 % [ 75 to 96 ] vs. 72 % [ 48 to 79 ] ; P = 0.002 ) , with a decrease in the percentage of BIS < 40 ( 7 % [ 2 to 17 ] vs. 21 % [ 11 to 38 ] ; P = 0.002 ) .