At 24 weeks , mean total cholesterol had increased by 7.26 and 11.47 mg/dL in the atazanavir/ritonavir and darunavir/ritonavir arms , respectively [ estimated difference -4.21 mg/dL ; 95 % confidence interval ( CI ) -12.11 to +3.69 mg/dL ; P = 0.75 ] .