In the second study , 18 subjects received a single dose of empagliflozin 10 mg , a single dose of empagliflozin 10 mg coadministered with a single dose of rifampicin 600 mg , and probenecid 500 mg BID for 4 days with a single dose of empagliflozin 10 mg on the second day in 1 of 6 randomized treatment sequences .