Among patients with intermediate-thickness melanomas , the 10-year melanoma-specific survival rate was 62.1 4.8 % among those with metastasis versus 85.1 1.5 % for those without metastasis ( hazard ratio for death from melanoma , 3.09 ; P < 0.001 ) ; among patients with thick melanomas , the respective rates were 48.0 7.0 % and 64.6 4.9 % ( hazard ratio , 1.75 ; P = 0.03 ) .