No significant changes in the levels of NT-proBNP ( -2,6274,956 vs. -2,9816,951 pg/ml , P = 0.845 ) , hsCRP ( -6.116.4 vs. -2.116.2 mg/L , P = 0.105 ) , cystatin C ( 0.0020.185 vs. 0.0090.216 mg/L , P = 0.904 ) , ACR ( -886.31,984.9 vs. -165.6825.2 mg/day , P = 0.124 ) were observed in either group .