The final favorable functional status ( mRS = 0-2 ) was 23 ( 65.7 % ) and 14 ( 40.0 % ) in the treated and placebo groups , respectively , which was strongly associated with allopurinol consumption ( OR = 4.646 , p = 0.014 ) and age 70 years ( OR = 0.139 , p = 0.005 ) in patients with ischemic stroke after adjusting for confounders .