The clinical indicators , including the initial Balthazar 's computed tomography ( CT ) score , acute physiology and chronic health evaluation II ( APACHE II ) scores on 1st , 3rd , 5th and 7th day , incidences and durations of complications and the serum C-reactive protein ( CRP ) , levels of MMP-9 on the 1st , 3rd , 5th and 7th day , were recorded and compared between the two groups .