Moreover , in exploratory analyses , we identified a number of possible interactions including between V249I and rs2669845 and dietary intake of -3 fatty acids ( P = .004 and P = .009 , respectively ) for AMD ; between rs2669845 and obesity ( P = .03 ) for neovascular AMD ; between T280M and complement component 3 ( C3 ) R102G for AMD ( P = .03 ) ; between rs2669845 and Y402H in complement factor H for AMD ( P = .04 ) ; and between rs2669845 , rs2853707 , and V249I and C3 R102G for neovascular AMD ( P = .008 ; .04 ; and .002 , respectively ) .