The mean ( standard deviation ) maximum plasma concentration ( C ( max ) ) and area under the plasma concentration-time curve from time zero to infinity ( AUC ( ) ) for the 2 mg dose were 214.8 ( 56.4 ) g/L and 2,251.3 ( 721.2 ) gh/L , respectively , and the corresponding values for the 4 mg dose were 310.0 ( 47.8 ) g/L and 6,942.6 ( 1,778.9 ) gh/L , respectively .