Within a minimum inhibitory concentration ( MIC ) range of 1-4 mg/L , the median ( IQR ) time LNZ plasma concentration persisted above MIC ( % T > MIC ) was significantly higher in the CI than the II group [ 100 ( 100-100 ) vs 100 ( 89-100 ) , p = 0.05 ; 100 ( 100-100 ) vs 82 ( 54.8-98 .8 ) , p = 0.009 ; 100 ( 74.2-100 ) vs 33 ( 30.2-78 .5 ) , p = 0.005 ; respectively ] .