The least square ( LS ) mean change in HbA1c concentration from baseline was 035 % ( SE 0068 ; -20 mmol/mol ) for the placebo group , -037 % ( 0068 ; -28 mmol/mol ) for the 125 mg group , -032 % ( 0070 ; -27 mmol/mol ) for the 25 mg group , -042 % ( 0070 ; -28 mmol/mol ) for the 50 mg group , -054 % ( 0068 ; -29 mmol/mol ) for the 100 mg group , and -055 % ( 0069 ; -30 mmol/mol ) for the 200 mg group .