The mean CPS values before treatment and those for early , delayed and long-term response were 9.73.0 and 9.52.7 ( p = 0.31 ) ; 6.13.6 and 5.43.6 ( p = 0.10 ) ; 5.33.7 and 4.13.7 ( p = 0.05 ) and 4.03.9 and 5.34.4 ( p = 0.05 ) , respectively .