In the BRV 50 mg/day group , statistical significance was also seen for the 50 % responder rate ( BRV 32.7 % vs. PBO 16.7 % ; p = 0.008 ) and median percent reduction from baseline in partial-onset seizure frequency/week ( BRV 30.5 % vs. PBO 17.8 % ; p = 0.003 ) .