Fewer water flushes [ mean 0.70.9 times ( range : 0-3 times ) in Group A vs 1.91.5 times ( range : 0-6 times ) in Group B , P < 0.05 ] in the pronase premedication group did not affect the endoscopic procedure times [ mean 766 s ( range : 647-866 s ) for Group A vs 760 s ( range : 678-854 s ) for Group B , P = 0.88 ] .