Serum from GA subjects reduced NK cell activating receptor CD16 [ from mean ( sem ) , 82 ( 2 ) % to 50 ( 4 ) % , P = 0.001 ] , IL-10 [ from 1700 ( 80 ) to 1200 ( 92 ) pg ml ( -1 ) , P = 0.001 ] , and IL-1 [ from 68 ( 12 ) to 19 ( 4 ) pg ml ( -1 ) , P = 0.01 ] .