Also , cord neuroketal levels were significantly lower in girls treated with allopurinol as compared with placebo treated girls : 18.0 pg/mL ( 95 % CI 12.1 to 26.9 ) in the ALLO group versus 32.2 pg/mL ( 95 % CI 22.7 to 45.7 ) in the CONT group ( geometric mean difference -16.4 ( 95 % CI -24.6 to -1.64 ) ) .