Serum C-reactive protein concentrations > 0.6 mg/dL and Crohn 's disease activity index scores > 151 at baseline were associated with a reduced likelihood of treatment success ( odds ratio , 0.40 ; confidence interval , 0.19-0 .87 ; P = 0.02 ; and odds ratio , 0.45 ; confidence interval , 0.21-0 .97 ; P = 0.04 , respectively ) .