In the intention-to-treat analysis , the risk of death was higher by 1.9 percentage points ( 90 % confidence interval [ CI ] , -0.6 to 4.4 ) with the beta-lactam-macrolide strategy than with the beta-lactam strategy and lower by 0.6 percentage points ( 90 % CI , -2.8 to 1.9 ) with the fluoroquinolone strategy than with the beta-lactam strategy .