Patients in the EGDT group received a larger mean ( SD ) volume of intravenous fluids in the first 6 hours after randomization than did those in the usual-care group ( 19641415 ml vs. 17131401 ml ) and were more likely to receive vasopressor infusions ( 66.6 % vs. 57.8 % ) , red-cell transfusions ( 13.6 % vs. 7.0 % ) , and dobutamine ( 15.4 % vs. 2.6 % ) ( P < 0.001 for all comparisons ) .