The mean and median survival times were 221.7 16.3 days [ 95 % confidence interval ( CI ) 189.8-253 .6 days ] and 210.0 17.5 days ( 95 % CI 175.8-244 .2 days ) in group A and 155.1 7.9 days ( 95 % CI 139.6-170 .5 days ) and 154.0 11.2 days ( 95 % CI 133.2-176 .0 days ) in group B ( P = 0.000 ) .