Ivabradine was associated with a similar relative risk reduction of the composite outcome in the three SBP groups [ SBP < 115 mmHg , hazard ratio ( HR ) = 0.84 , 95 % confidence interval ( CI ) 0.72-0 .98 ; 115 SBP < 130 mmHg , HR = 0.86 , 95 % CI 0.72 to 1.03 ; SBP 130 mmHg , HR = 0.77 , 95 % CI 0.66 to 0.92 ; P interaction = 0.68 ] .