At 48 months , achievement of the low-density lipoprotein cholesterol goal improved from 59.1 % to 73.6 % ( P < 0.001 ) , achievement of the systolic blood pressure goal improved from 51.6 % to 65.1 % ( P < 0.001 ) , achievement of the glucose goal improved from 74.9 % to 80.7 % ( P = 0.0101 ) , and nonsmoking improved from 74.4 % to 80.9 % ( P < 0.0001 ) .