Significant improvement in BCVA over baseline was observed in both groups at all six study visits ( IVR group : p = 0.0003 , 0.0001 , 0.0018 , 0.0145 , 0.0107 , 0.005 ; IVR+IVTA group : p = 0.0001 , 0.0001 , 0.0004 , 0.0068 , 0.0007 , 0.0002 ) , with no significant BCVA differences between groups .