The average maximum concentration ( Cmax ) and area under the concentration-time curve from time 0 to infinity ( AUC ) values of KM-023 for the 75-600 mg doses in the single-dose study ranged from 440.2 ng/mL to 1,245.4 ng/mL and 11,142.4 ng h/mL to 33,705.6 ng h/mL , respectively .