This study is registered with ClinicalTrials.gov , number : NCT02090504 RESULTS : A significant decrease of the mean total CIWA-Ar score from baseline to the end of the study was found in both the SMO ( p < 0.0001 ) and the oxazepam group ( p < 0.0001 ) , with no significant differences between the two treatments ( p = 0.21 ) .