The relative dose intensity of S1 ( 89.5 % 20.6 % vs 98.3 % 5.2 % , P = .005 ) and oxaliplatin ( 91.4 % 16.8 % vs 99.0 % 4.2 % , P = .007 ) during CCRT was lower in arm A compared with arm B. Three patients in arm A , compared with none in arm B , died within 90 days after surgery .