In A-to-Z , the incidence of a 1.5-fold or 0.3 mg/dL rise in serum creatinine was 11.4 % for subjects randomized to a high-potency statin regimen versus 12.4 % for those on a delayed moderate-potency regimen ( odds ratio [ OR ] , 0.91 ; 95 % confidence interval [ CI ] , 0.76 to 1.10 ; P = 0.33 ) .