The incidence of PONV at 2 , 24 , and 72 h periods was lower in the palonosetron group than the placebo group ( 29.2 , 45.8 , and 50.0 % in the palonosetron group vs. 50.0 , 62.2 , and 66.2 % in the placebo group , p = 0.010 , 0.048 , 0.047 , respectively ) .