The levels of biochemical indicators including body mass index ( BMI ) , glucose hemoglobin A1C ( GHbA1C ) , insulin resistance ( HOMA-IR ) , fasting blood glucose ( FBG ) , fasting insulin ( FIns ) , and serum triglycerides ( TG ) as well as serum RBP-4 and APN level were measured pre-treatment and 12 weeks after treatments .