Analysis of HV , bone age and pubertal stage in 92 TS girls ( 7-13 years ) randomised to Ox ( 0.05 mg/kg/day ; max : 2.5 mg/day ) or placebo from 9 years , and EE2 ( year 1 : 2 g/day ; year 2 : 4 g/day ; year 3 : 6/8/10 g/day4 months ) or placebo at 12 years with EE2 at 14 years .