At approximately 3-week follow-up ( 21.315.8 days ) , longitudinal and SR for the group with MR or PE had increased significantly compared with diagnosis ( : -16.44.3 % vs -18.60.5 % , P = .03 ; SR : -1.30.6 vs -1.80.4 sec ( -1 ) , P = .008 ) , coincident with resolution of MR or PE .