The hypotheses were that WAI of uNTx/Cr would be > 40 % ( including > 40 % for the lower limit of the 90 % confidence intervals [ CIs ] ) for older men and postmenopausal women , that there would be no important differences in area under the curve from 0 to 168 hours ( AUC0-168 h ) between men and women , and that odanacatib would be safe and well tolerated .