The median time to fever clearance was 4.70 days ( IQR 2.98-5 .90 ) in the ofloxacin group versus 3.31 days ( IQR 2.29-4 .75 ) in the gatifloxacin group ( HR = 1.59 , 95 % CI 1.16 to 2.18 , p = 0.004 ) .