Ninety consecutive acute anterior myocardial infarction patients with heavy thrombosis burden [ ( 59.8 11.5 ) years old ] were randomly assigned to thrombus aspiration group ( Group A , n = 30 ) , thrombus aspiration and intracoronary tirofiban bolus ( 25 g/kg prior to the first balloon inflation , Group B , n = 30 ) , thrombus aspiration and intracoronary tirofiban combined with nitroprusside bolus ( 200 g prior to the first balloon inflation , Group C , n = 30 ) with random number table .