At the end of the trial , inhalation score ( Mean estimated difference [ delta ] , 13.5 % ; 95 % Confidence Interval [ CI ] , 10.8-16 .1 ; P < .0001 ] and medication adherence [ ( delta , 8.51 % ; 95 % CI , 4.63-12 .4 ; P < .0001 ) were significantly higher in the intervention group compared to the control group .