When subjects were divided into NERD and RE , symptom relief in cont/on-demand were 33.3 % / 41.2 % at baseline ( n.s. ) , 43.8 % / 64.3 % at 8 weeks ( n.s. ) , 50.0 % / 42.9 % at 16 weeks ( n.s. ) , and 50.0 % / 69.2 % at 24 weeks ( n.s. ) in NERD , while those were 68.3 % / 51.2 % at baseline ( n.s. ) , 76.3 % / 51.3 % at 8 weeks ( p < 0.05 ) , 70.6 % / 59.0 % at 16 weeks ( n.s. ) , and 72.7 % / 75.7 % at 24 weeks ( n.s. ) in RE , respectively .