Adverse events were comparable between zirconium cyclosilicate and placebo , although edema was more common in the 15-g group ( edema incidence : 2/85 [ 2 % ] , 1/45 [ 2 % ] , 3/51 [ 6 % ] , and 8/56 [ 14 % ] patients in the placebo , 5-g , 10-g , and 15-g groups ) .