Perioperative heart rate , blood pressure and oxygen saturation and postoperative pain at rest and during cough , side effects and rescue analgesic requirements were recorded at the 30 ( th ) and 60 ( th ) minutes and the 2 ( nd ) , 4 ( th ) , 6 ( th ) , 12 ( th ) , 24 ( th ) , 36 ( th ) , 48 ( th ) , and 72 ( nd ) hour .