Methylprednisolone , compared with placebo , did not reduce the risk of death at 30 days ( 154 [ 4 % ] vs 177 [ 5 % ] patients ; relative risk [ RR ] 087 , 95 % CI 070-107 , p = 019 ) or the risk of death or major morbidity ( 909 [ 24 % ] vs 885 [ 24 % ] ; RR 103 , 95 % CI 095-111 , p = 052 ) .