From January 2001 to April 2011 , 194 patients with vulvar non-neoplastic epithelial disorders were divided into three groups according to therapy regimens received , ie , chlortetracycline treatment group ( 72 cases ) , chlortetracycline + beclomethasone treatment group ( 66 cases ) , and beclomethasone treatment group ( 56 cases ) ; their local changes of vulvar lesions were observed and efficacy of these treatment profiles was evaluated after one year .