Results from a clinical study using the indocyanine green dilution method in 36 subjects with type 2 diabetes indicate that the estimated plasma volumes are considerably lower when using the traditional back-extrapolation method than when using the proposed back-extrapolation method ( mean ( standard deviation ) plasma volume = 26.8 ( 5.4 ) mL/kg for the traditional method vs 35.1 ( 7.0 ) mL/kg for the proposed method ) .