Whole-body glucose counterregulation , the difference in glucose infusion rates required to maintain the glycaemic goal between the hypoglycaemic and euglycaemic clamps , was improved in T1DM/ITx ( + ) ( 7.81.3 mol kg ( -1 ) min ( -1 ) ) compared with T1DM/ITx ( - ) ( 0.30.9 mol kg ( -1 ) min ( -1 ) ) , but was ~ 45 % lower than in controls ( 14.12.1 mol kg ( -1 ) min ( -1 ) ) .