The double-blind , randomised , placebo-controlled study was conducted in the Department of Obstetrics and Gynaecology of the Ondokuz Mayis University , Samsun , Turkey , from April 2013 to January 2014 , and comprised patients scheduled for in-office endometrial biopsy.They were divided into three groups : Group P , 5ml of 0.9 % saline intrauterine ; Group L , 5ml of 2 % lidocaine intrauterine ; and Group LD , 5ml of 2 % lidocaine intrauterine 10min before the procedure plus 50mg of rectal diclofenac sodium .