In all control children , FMD ( % ) associated inversely with Lp ( a ) concentration : ( [ % / 1000 mg/L ] = -3.74 , 95 % CI [ -6.43 , -1.45 ] ; P = .007 ) and in 68 familial risk children ( = -4.92 , 95 % CI [ -8.18 , -1.66 ] ; P = .0037 ) .