Per-protocol treatment effectiveness was 59 % ( 95 % CI 45 % to 73 % ) for PPI-CA and 73 % ( 95 % CI 58 % to 87 % ) for ST. Based on intention to treat , effectiveness was 55 % ( 95 % CI 41 % to 69 % ) for PPI-CA and 57 % ( 95 % CI 43 % to 71 % ) for ST. Of 77 participants ( 43 PPI-CA , 34 ST ) with 100 % adherence , effectiveness was 63 % ( 95 % CI 43 % to 82 % ) for PPI-CA and 81 % ( 95 % CI 63 % to 99 % ) for ST.