On univariable and multivariable analysis , both acute and chronic inflammation were found to be significantly associated with a lower PCa risk ( acute univariable : odds ratio [ OR ] , 0.65 [ P < .001 ] and multivariable : OR , 0.75 [ P = .012 ] and chronic univariable : OR , 0.61 [ P < .001 ] and multivariable : OR , 0.65 [ P < .001 ] ) .