In secondary analysis , there was no significant effect of the intervention on the risk for incident carotid disease during the 5 years of postintervention follow-up from 2005 to 2010 ( hazard ratio , 1.24 ; 95 % confidence interval , 0.9-1 .7 ) and no significant effect during cumulative follow-up from 1994 to 2010 ( hazard ratio , 1.13 ; 95 % confidence interval , 0.9-1 .4 ) .