We examined the effects of 12 wk of aerobic exercise combined with either a low-glycemic index diet ( 40 U ) plus exercise ( LoGIX ) or a high-glycemic index diet ( 80 U ) diet plus exercise ( HiGIX ) on plasma leptin and adiponectin ( total and high molecular weight [ HMW ] ) in 27 older obese adults ( age = 65 0.5 yr , body mass index = 34.5 0.7 kgm ) .