The most common adverse events with everolimus were stomatitis ( 314 [ 67 % ] of 472 patients in the everolimus group vs 77 [ 32 % ] of 238 patients in the placebo group ) , diarrhoea ( 267 [ 57 % ] vs 111 [ 47 % ] patients ) , and alopecia ( 221 [ 47 % ] vs 125 [ 53 % ] ) .