Further analyses highlighted improvements in apathy ( F = 5.3 , df = 1 ; 300 , p = 0.017 ) , night-time behaviours ( F = 3.1 , df = 1 ; 301 , p = 0.050 ) , and appetite items ( F = 11.6 , df = 1 ; 301 , p = 0.005 ) , but not irritability ( p = 0.092 ) and anxiety ( p = 0.125 ) .