Maternal TSH ( p = 0.276 ) and T4 ( p = 0.074 ) concentrations did not differ between the groups over the course of the study , nor did infant TSH ( p = 0.597 ) and T4 ( p = 0.184 ) concentrations , but the number of infants with thyroid hypofunction was lower ( p = 0.023 ) in the indirect supplementation group than the direct supplementation group .