At week 12 , adjusted mean difference versus placebo in change from baseline in mean 24-h DBP ( ABPM ) was -1.36 mmHg ( 95 % CI -2.15 , -0.56 ) with 10 mg empagliflozin and -1.72 mmHg ( 95 % CI -2.51 , -0.93 ) with 25 mg empagliflozin ( both P < 0.001 ) .