The Sano clan in Oniya, Hikami County (present Oniya, Kaibara-cho, Tanba City), was originally a distinguished family of a daimyo of the Edo bakufu after being gokenin (a lower-ranked direct retainer) of the Kamakura bakufu, a retainer of Kamakura kubo (the governor-general of the Kanto region) in the Muromachi bakufu, and a daimyo under the Toyotomi government.
氷上郡大新屋（現・丹波市柏原町大新屋）の佐野氏は、鎌倉幕府御家人、室町幕府鎌倉公方の家臣、豊臣政権下の大名などを経て江戸幕府の大名となった名家であった。