In 2005 the Hokkaido town of Kamishihoro-cho under the jurisdiction of the Tokachi subprefectural claimed to be area unaffected by pollen and in 2006 the Amami Islands in Kagoshima Prefecture began to attract tourists (pollinosis patients) for the purpose of recuperation with the Ministry of Land, Infrastructure, Transport and Tourism taking applications and operating the trips on a trial basis.
2005年に北海道十勝支庁管内の上士幌町が避花粉地として名乗りをあげたほか、続いて2006年には鹿児島県の奄美諸島も療養や保養目的の観光客（花粉症患者）誘致を始め、これは国交省がモニターツアーの募集を行った。