As a result of the Siege of Odawara by Hideyoshi TOYOTOMI in 1590, however, the Gohojo clan and the Ashikaga-Nagao clan were overthrown and the Ashikaga School lost its patrons.
しかし1590年の豊臣秀吉による小田原の役の結果、後北条氏と足利長尾氏が滅び、足利学校は庇護者を失うことになった。