During the Sengoku Period, the areas along Tosan-do Road were power base of various feudal lords such as theTakeda clan (Kai Province), the Ogasawara clan (Shinano Province), the Kanamori clan (Hida Province) and the Oda clan (Mino Province).
戦国時代の東山道は、武田氏（甲斐国）や小笠原氏（信濃国）や金森氏（飛騨国）や織田氏（美濃国）などの地盤であった。