Nagayasu and the Miyoshi army, whose home bases were Noda Castle and Fukushima Castle, fiercely resisted in the continuous battles known as 'Genki Soran,' however, Nobunaga's attacks were so relentless that they triggered a sense of crisis in Ishiyama Hongwan-ji Temple, with their main base in Settsu, which was also opposed Nobunaga; finally they were prompted to join the anti-Nobunaga armies (outbreak of Ishiyama Gassen).
「元亀争乱」と呼ばれる一連の動乱において、野田城及び福島城を根拠地とする長逸ら三好軍の抵抗は激しかったが、これに対する信長の攻撃は苛烈なものであり、同じく信長と不仲な摂津に本拠をもつ石山本願寺の危機感を煽ることになり、ついには本願寺の反信長陣営への参加を促すことになる（石山合戦の勃発）。