He followed Yoshiaki and fought against Nobunaga holing up in Ishiyama-jo Castle in Omi Province when the battle between Nobunaga and Yoshiaki began and Nobunaga was under siege.
信長包囲網が敷かれ信長と義昭の戦いが始まると義昭に従って信長と敵対し、近江石山城に立て籠もって抗戦した。