The section between Horikawa-dori Street and Senbon-dori Street contains two wide lanes in each direction, under which Kyoto City Subway Tozai Line runs and where Nijojo-mae Station and Nijo Station are located as well.
堀川通～千本通は片道2車線の広い道路で、京都市営地下鉄東西線が地下を通っており、二条城前駅、二条駅がある。