Six-car sets are mainly operated as local trains on the Yamatoji Line and the Osaka Higashi Line, but during rush hour they are also used as rapid trains on the Wakayama Line and Sakurai Line.
6両編成は主として大和路線普通列車およびおおさか東線での運用だが、ラッシュ時には快速や和歌山線、桜井線にも運用される。