In 1573, Yoshiaki ASHIKAGA stood against Oda by himself and Yoshitsugu MIYOSHI and Hisahide MATSUNAGA soon followed him, and this marked the first time for the entire Miyoshi clan to come together against Oda.
元亀4年（1573年）、足利義昭自身が決起し、これに三好義継、松永久秀らが呼応してはじめて三好一族の足並みが反織田で一致した。