He also greatly contributed to the development of western studies by his wide-ranging exchanges with the central people of that time in politics, culture, diplomacy such as Toshiakira KAWAJI and Hidetatsu EGAWA (key Edo shogunate figures), Kazan WATANABE and Hoshu KATSURAGAWA (Dutch scholars), Shogo MITSUKURI (geographer), Kokan SHIBA and Buncho TANI (painters), Shuhan TAKASHIMA (ballistic specialist), Kodayu DAIKOKUYA (returnee from Russia), Sanai ADACHI, Kunpei EGAWA, Sakusaburo NAKAYAMA (Japanese-Dutch translator), Johan Willem de Sturler (curator of Dutch trading house).
また、川路聖謨、江川英龍などの幕府要人、渡辺崋山、桂川甫周などの蘭学者、箕作省吾などの地理学者、司馬江漢、谷文晁ら画家、砲術家　高島秋帆、海外渡航者の大黒屋光太夫、足立左内、潁川君平、中山作三郎ら和蘭通詞、オランダ商館長（カピタン）のスチュルレ（JohanWillemdeSturler）など、当時の政治、文化、外交の中枢にある人々と広く交流を持って洋学界にも大きく寄与した。