Yusai HOSOKAWA and Tadaoki HOSOKAWA, who succeeded the branch family which started from Yorinaga HOSOKAWA, the Shugo of the Izumi Province, survived under the Oda government as daimyo, and continued to exist as a lord in the Kumamoto Domain during the Edo period.
なお、分家の和泉国守護・細川頼長から始まる系統を継いでいた細川幽斎・細川忠興らは織田政権下を大名として生き延び、江戸時代には熊本藩として存続した。