After returning to Osaka, he translated Dutch books for Koishi and others, and opened his private school and clinic, Shikan-do, where he both taught and practiced as a physician.
大坂へ戻ると小石らのため蘭書を翻訳し、医院と学塾を兼ねた私塾である絲漢堂を開き診療と教育活動に務める。