In 1629, when Iemitsu was stricken with smallpox, she visited Ise Jingu Shrine to pray that he would be cured, and in the tenth month of that year she went to Kyoto on her way back and tried to arrange an audience at court.
寛永6年（1629年）には、家光の天然痘治癒祈願のため伊勢神宮に参拝し、そのまま10月には上洛して御所への昇殿を図る。