Along the middle and lower Kizu-gawa River to the north of Kizugawa City run the Nara Line (West Japan Railway Company) and the National Route 24 on the east side of the river and the Katamachi Line (West Japan Railway Company) and the Kintetsu Kyoto Line (Kintetsu Railway) on the west side.
木津川市以北の中・下流域では、東岸をJR西日本奈良線と国道24号（奈良街道）が、西岸をJR西日本片町線と近畿日本鉄道近鉄京都線とが沿う。