Mochitsune HOSOKAWA, the fourth family head counting from Akiharu, gained trust from the sixth shogun, Yoshinori ASHIKAGA, and he served as an additional post of the Shugo of Mikawa Province, replacing Yoshitsura ISSHIKI who was said to have died in a battle in 1440.
詮春から数えて4代目の細川持常は、6代将軍足利義教の信任が厚く、永享12年（1440年）に戦死したとされる一色義貫に代わり三河国守護職も兼任した。