As the Nijo family was close to samurai governments as seen in the fact that the heads of the Nijo family were granted use of a portion of the real name of seii taishogun (literally, "great general who subdues the barbarians") of Muromachi bakufu (Japanese feudal government headed by a shogun) and the Edo bakufu, however, the time period in which members of the Nijo family were in a position of Sekkan during the Muromachi period was longer than that of other members of gosekke.
ただ、歴代の当主が室町幕府と江戸幕府の征夷大将軍の偏諱を受けるなど武家政権と親密であった二条家は、室町時代において摂関を勤める期間が他の五摂家と比べて長かった。