In the Tosa Domain, Tosa kinnoto (loyalist clique of Tosa) led by Zuizan TAKECHI gained power and was opposed to Toyo YOSHIDA, who was the koko no shin (a trusted retainer) of Yodo.
土佐藩でも武市瑞山を首領とする土佐勤王党が台頭し、容堂の股肱の臣である吉田東洋と対立。