However, in 1574 Gansho-ji Temple in Nagashima-cho, Ise-no-kuni (Mie Prefecture) was destroyed by the Oda clan and the resistance movements in various regions settled as Ikko-ikki, which recovered Echizen from the Oda clan, were destroyed in 1575; and the navy of the Mori clan, which was allied with Hongan-ji Temple in Kizugawa-no kassen, was defeated by the navy of the Oda clan in 1578, assuming the defeat of Hongan-ji Temple in various places other than the premises of Hongan-ji Temple.
しかし、1574年には伊勢国長島町(三重県)の願證寺が織田氏によって滅ぼされ、1575年に越前を織田氏から奪還した一向一揆が覆滅されるなど各地の抵抗がそがれ、1578年には木津川の合戦で本願寺と同盟する毛利氏の水軍が織田水軍に敗れるなど、本願寺の外では敗北を重ねていった。