A quadruple track section separates the Yamatoji Line and Osaka Loop Line between Tennoji and Shin-Imamiya, and from Shin-Imamiya, trains arriving and departing from JR Nanba also run on a track separated from the Osaka Loop Line.
天王寺-新今宮間は大阪環状線と別線（複々線）で、新今宮からも大阪環状線とは別線を進むJR難波発着の列車がある。