He had children including: Saneyoshi ICHIJO, Empress Dowager Shoken (empress consort to Emperor Meiji), Akiko (Yasunobu YANAGISAWA's lawful wife), an adopted daughter Mine (Yoshikuni HOSOKAWA's lawful wife) and an adopted daughter Mikako ICHIJO (Yoshinobu TOKUGAWA's midaidokoro [shogun's lawful wife]).
子に一条実良、昭憲皇太后（明治天皇皇后）、明子（柳沢保申正室）、養女・峯（細川韶邦正室）、養女・一条美賀子（徳川慶喜御台所）らがいる。