The second head of the family, Sadayori NONOMIYA, an adopted son from the Nakanoin family, learned Japanese and Chinese culture from Banzan KUMAZAWA, and the third head of the family, Sadamoto NONOMIYA, also an adopted son from the Nakanoin family, was well known as one of the Yusoku-shitenno (the four specialists of the ancient practices) (Kinzumi SHIGENOI, Tokikata HIRAMATSU, Motokazu HIGASHIZONO and Sadamoto NONOMIYA) and a sponsor to restore the Kamo Festival.
2代野宮定縁・3代野宮定基は中院家からの養子で、定縁は熊沢蕃山に和漢の学を学び、定基は有職四天王（滋野井公澄・平松時方・東園基量・野宮定基）の一人として名高く、賀茂祭の復興にも尽力した。