At the Battle of Sekigahara after Hideyoshi's death, they sided with Mitsunari Ishida's Western Army, but after the battle they were pardoned by Ieyasu and continued to exist in the 300,000 koku Yonezawa domain in Dewa Province until the end of the Shogunate.
秀吉の死後、関ヶ原の戦いでは石田三成ら西軍に付いだが、戦後に家康から罪を許され、出羽国米沢藩30万石で幕末まで存続した。