When Kenmu Restoration began, Takasada led the army with his father Takasuke into Kyoto on August 2 ("Taiheiki" (The Record of the Great Peace)), however, Imperial Prince Morinaga was ousted and was sent to Kamakura as a criminal, so Takasada was killed in January 1335 (December 1334 in old calendar) by the Kenmu regime which intended to remove the remnants of the group related to the imperial prince.
建武の新政が始まると6月13日(旧暦)、父の隆資とともに兵を率いて入京した（『太平記』）が、護良親王が失脚して鎌倉に押送されると、その余党を取り除こうとした建武政権の手により1334年（建武(日本)元年）12月に殺害された。