Including ONO no Imoko who became Kenzuishi (a Japanese envoy to Sui Dynasty China), many people from the Ono clan worked as officials who established relations with China such as Kentoshi (a Japanese envoy to Tang Dynasty China); also many people from the Ono clan worked as local officials in such regions as Tohoku and Kyushu regions.
小野氏は、遣隋使となった小野妹子をはじめ、遣唐使などを務めたものが多く、東北や九州などの地方官僚などを務めたものも多い。