This happened right after the Tenchugumi rebellion, so the reaction of the shogunate was quick, as soon as they received reports from the keeper of the magistrate's office, they set the Toyooka Domain, the Izushi Domain and the Himeji Domains, a day after the rising of the army on the thirteenth, nine hundred soldiers from the Toyooka Domain and one thousand soldiers from the Himeji Domain marched to Ikuno.
天誅組の変の直後とあって、幕府側の動きは早く、代官所留守から通報を受けるや豊岡藩、出石藩、姫路藩が動き、挙兵の翌13日には出石藩兵900人と姫路藩兵1000人が生野へ出動している。