In 1493, the kanrei Masamoto HOSOKAWA established a dictatorship after overthrowing Yoshitane ASHIKAGA, the tenth seii taishogun (literally, "great general who subdues the barbarians") (this incident known as the Meio Coup).
明応2年（1493年）、管領・細川政元は、10代征夷大将軍・足利義稙を廃立し専制権力を樹立した（明応の政変）。