Meanwhile, the main group of the bakufu also put more oppression to the persons who took part in the Hitotsubashi group (group supporting Yoshinobu from the Hitotsubashi-Tokugawa family) in which the Mito Domain was playing the central role regarding the problem of a successor of the Seii Taishogun Iesada TOKUGAWA (Ansei no Taigoku ［suppression of extremists by the Shogunate］).
一方で、征夷大将軍徳川家定の後継者問題を巡る対立で水戸藩が中心となっていた、いわゆる一橋派に加担していた人物への弾圧を強めていった（「安政の大獄」）。