During the Otate Disturbance, Kekeiin, who was Kagetora's wife and Kagekatsu's elder (or younger) sister, refused Kagekatsu's order for surrender and killed herself. Norimasa, Kagetora's adoptive grandfather, attempting to make overtures for peace was killed by a Kagekatsu soldier along with Domanmaru UESUGI, Kagetora's eldest son (alternative accounts have them surviving after receiving shelter from the Ichikawa clan, a powerful clan in Shinano Province).
乱中において、景虎正室である実姉（妹）華渓院は景勝の降伏命令を拒んで自害、和議を申し出ようとした養祖父の憲政が景虎の嫡男上杉道満丸（信濃国豪族市川氏に庇護され、生存していた説あり）とともに景勝の兵によって討たれるなど、