In 1367 (Shohei 22/Joji 6) he entrusted his heir, Yoshimitsu, who was born to him by his concubine, KI no Yoshiko, to Yoriyuki HOSOKAWA, then succumbed to illness and died.
1367年（正平22年/貞治6年）に、側室の紀良子との間に生まれた幼少の嫡男義満を細川頼之に託して、病により死去する。