25th head priest Mansai, who became the adopted son of Yoshimitsu ASHIKAGA, was appointed head priest of Godai-ji Temple in 1396 before being given the imperial title Ju-Sango and later going on to become referred to as 'Kokui no Saisho' (Buddhist priest who also serves as a government minister) for his backing of the Muromachi Shogun Yoshinori ASHIKAGA.
特に足利義満の猶子となった25世満済は、応永3年（1396年）に醍醐寺座主に任じられ、続いて准三后となり、後には足利義教の室町幕府征夷大将軍擁立にも活躍したため、「黒衣の宰相」と呼ばれた。