Mitsuharu, Ujiharu's son, inherited the shugo family of Awaji province and the family continued for generations as one of powerful branch families of the Hosokawa clan, but was destroyed by the Miyoshi clan in the reign of Hisaharu HOSOKAWA at the beginning of the Sengoku period (the period of warring states) and the family line ended.
淡路守護家は子の満春が継ぎ、代々細川氏の有力な分家の一つとして存続したが、戦国時代(日本)初期の細川尚春の時代に三好氏滅ぼされ断絶した。