With Yoritsuna's support, Sadatoki established the tyranny of the patrimonial head of the main branch of the Hojo clan in which Sadatoki himself was the leader, but he came to be disturbed by Yoritsuna's reins of power and, finally in 1293, taking advantage of the turmoil caused by the Kamakura Earthquake, Sadatoki invaded Yoritsuna's house in Gyojigayatsu in Kamakura and made him commit suicide with his sword.
貞時は、頼綱に支えられて自らを頂点とする得宗専制体制を敷いたが、頼綱の権勢に不安を抱くようになり、ついに1293年（永仁元年）、鎌倉大地震の混乱に乗じて鎌倉・経師ヶ谷の頼綱邸を攻撃し、頼綱を自刃させた。