Takeinadane no mikoto served two emperors, Emperor Keiko and Emperor Seimu, and he distinguished himself in the military expedition to the east lead by Yamato Takeru (a legendary hero and a son of Emperor Keiko), taking command of the army as vice shogun.
景行天皇と成務天皇の二代の間、朝廷に仕え、ヤマトタケル東征の際、副将軍として軍を従え、軍功を挙げたとされる。