He suffered a crushing defeat in the Battle of Imayama with his younger brother Chikasada being killed by Takanobu RYUZOJI after invading Hizen Province again in 1570 and had to reconcile with Takanobu in unfavorable conditions.
元亀元年（1570年）、再度肥前に侵攻するが今山の戦いで龍造寺隆信に弟の親貞を討たれるという大敗を喫し、隆信と不利な条件で和睦せざるを得なくなった。