Sengoku Period warlords, such as Dokan OTA and Ujitsuna HOJO, prayed to that diety for good fortune on the battlefield at Kanda Myojin; furthermore, at the occasion of the Battle of Sekigahara, the victory of Ieyasu TOKUGAWA was prayed there.
神田明神は戦国時代の太田道灌・北条氏綱等の武将が武運祈願のため崇敬するところとなり、さらに関ヶ原の戦いの際には徳川家康戦勝祈祷を行った。