Although Emperor Komei suffered from a malignant hemorrhoids for a long time, as it was previously mentioned, apart from this the Emperor was quite healthy and it was written in Tadayasu NAKAYAMA's diary, as mentioned before, he said, 'I was very shocked to know the Emperor suffered from unusual diseases like smallpox, since he had been very healthy and did not even get the flu recently.'
孝明天皇は前述の通り長年のあいだ悪性の痔に悩まされていたが、それ以外では至って壮健であり、前出の中山忠能日記にも「近年御風邪抔一向御用心モ不被為遊御壮健ニ被任趣存外之儀恐驚」（近年御風邪の心配など一向にないほどご壮健であらせられたので、痘瘡などと存外の病名を聞いて大変驚いた）との感想が記されている。