In 1858 Naosuke II became tairo (chief minister) and concluded the Treaty of Amity and Commerce between the United States and Japan and set the lord of Kii Province Iemochi TOKUGAWA up as the 14th shogun.
58年に大老に就任した井伊直弼は、日米修好通商条約を締結、紀伊国藩主徳川家茂を14代将軍にした。