Takakuni and Tadakata attacked their forces at the Katsura-gawa River but they were defeated and fled to Sakamoto in Omi with shogun Yoshiharu (The Battle of Katsura-gawa River).
高国・尹賢は桂川で迎え撃つが敗れ、将軍義晴を擁して近江坂本に逃亡（桂川の戦い）。