Mitsuhide was aghast at Hideyoshi's coming and fought for him at Yamazaki on June 13, but Mitsuhide's troops were severely defeated because Tuneoki IKEDA and Nagahide NIWA, and Kiyohide NAKAGAWA and Ukon TAKAYAMA, who were followers of Mitsuhide, turned to support Hideyoshi so that Mitsuhide's force became smaller than Hideyoshi's force, and Mitsuhide was killed by nameless warriors (the battle at Yamazaki).
秀吉勢の出現に驚愕した明智光秀は、6月13日、山崎において秀吉と戦ったが、池田恒興や丹羽長秀、さらに光秀の寄騎であった中川清秀や高山右近までもが秀吉を支持したため、兵力で劣る光秀方は大敗を喫し、光秀は落武者狩りにより討たれた（山崎の戦い）。