Around this time, the relationship between Kenshin UESUGI in Echigo Province and Nobunaga worsened and Kenshin made peace with the Ishiyama Hongan-ji Temple in 1576.
この頃、越後国の上杉謙信と信長との関係は悪化し、謙信は天正4年（1576年）に石山本願寺と和睦。