After studying under a doctor of his native domain Seian TAKEBE, at the age of 25, he went to Edo to enter a private school called Shirando ran by a rangakusha Gentaku OTSUKI who was a senior pupil of TAKEBE in the same hometown.
郷里の藩医・建部清庵に学び、25歳で江戸へ出て、建部の弟子であり郷里の先輩でもある蘭学者・大槻玄沢の芝蘭堂に入塾。