She had four children with Naoshige: the eldest daughter Chizuru (the wife of Yasutoshi TAKU, a chief retainer of the Saga domain), the second daughter Hikogiku (the wife of Naotaka ISAHAYA, a chief retainer of the Saga domain), the eldest son Katsushige NABESHIMA (the first lord of the Saga domain) and the second son Tadashige NABESHIMA (the first lord of the Kashima domain).
直茂の間には、長女千鶴（佐賀藩家老多久安順室）、次女彦菊（佐賀藩家老諫早直孝室）、長男鍋島勝茂（佐賀藩初代藩主）、次男鍋島忠茂（鹿島藩初代藩主）を儲けた。