Sasagawa Kubo was established when Mitsukane ASHIKAGA, the third Kamakura Kubo, sent his younger brother, Mitsunao ASHIKAGA, to Sasagawa in Asaka County in Mutsu Province for governing the Oshu region.
3代鎌倉公方足利満兼が奥州統治のため弟の足利満直を陸奥国安積郡の篠川（ささがわ）に派遣して成立。