The Train Series 221 is also mainly used for rapid trains that start from and terminate at Osaka Station; however, the JNR/JR Suburban Train Series 113 and the JR (West) Commuter Train Series 207 are often used during the rush hour, while the Train Series 113 and Series 221 are used for both local and rapid trains that go above Sasayamaguchi Station.
大阪発着の「快速」にも221系電車が中心的に使われるが、ラッシュ時には国鉄113系電車電車とJR西日本207系電車電車も使われ、篠山口以北に乗り入れる普通・快速には113系と221系が使われる。