In 1832, Sanei became a doctor of Kishiwada in Izumi Province and was later appointed as a translator belonging to Tenmonkata (Astronomical Institute) of bakufu (Japanese feudal government headed by a shogun).
天保3年（1832年）、和泉国岸和田医となり、のち幕府の天文方阿蘭陀書籍和解御用、すなわち翻訳係となる。