In August of 1516, Tomooki OGIGAYATSU-UESUGI attacked Tamanawa-jo Castle in support of the Miura clan but Soun crushed the assault and attacked Misaki-jo Castle, where Yoshiatsu and Yoshioki were hiding.
永正13年（1516年）7月、扇谷上杉朝興が三浦氏救援のため玉縄城を攻めるが早雲はこれを打ち破り、義同・義意父子の篭る三崎城に攻め寄せた。