After the Meiji Restoration, Yodo assumed the position of naikoku jimu sosai (the director general of Domestic Affairs Office), but he did not get along with the others who used to be in ranks lower than himself, such as vassals and people of the domain, and resigned from the position in 1869.
明治維新後は内国事務総裁に就任したが、かつて家臣や領民であったような身分の者とは馴染まず、明治2年（1869年）に辞職。