During Honnoji Incident in 1582, Sadakatsu was at his own residence, on the opposite side of Honno-ji Temple, but he rushed to Myokaku-ji Temple, the residence of Nobunaga's legal son, Nobutada ODA.
天正10年（1582年）の本能寺の変では本能寺向かいの自邸にいたが、信長の嫡男・織田信忠の宿所の妙覚寺に駆け込んだ。