As Hidetsugu TOYOTOMI, who had been assigned to the position of Kanpaku (chief adviser to the Emperor) from Hideyoshi as his adopted heir and who was his cousin and brother-in-law, was ousted and forced to commit seppuku in 1595, Hideyori was brought up in Fushimi-jo Castle as the successor of the Toyotomi clan.
文禄4年（1595年）、秀吉から養嗣子として関白職を譲られていた従兄で義兄の豊臣秀次が失脚して切腹したため、秀頼が豊臣氏の後継者として伏見城で育てられた。