His eldest daughter, Tsuru UESUGI, became a wife of Tsunataka SHIMAZU, the lord of the Satsuma domain, the second daughter, Akuri UESUGI, married Masatake TSUGARU, a kotaiyoriai (landholding liege vassals with alternate attendance obligations) hatamoto, and the third daughter, Kiku UESUGI, also became a wife of Tadahira SAKAI, a hatamoto (Princess Tsuru was divorced from Tsunataka, and Princess Kiku had lost her husband, but later she became a wife of Tsunenari OINOMIKADO, a court noble, and gave birth to a son and a daughter).
長女上杉鶴は薩摩藩主島津綱貴の室、次女上杉阿久利は交代寄合旗本津軽政たけの室、3女上杉菊も旗本酒井忠平の室となっている（鶴姫は綱貴に離縁され、菊姫も死別するが、のちに公家大炊御門経音の室となって1男1女を産む）。