The Emperor Komei had suffered from hemorrhoid since around 1849 and other several doctors from Tenyakuryo provided medical care using Chinese herbal drugs, which, however, had no effect and indicated the limitations of internal treatment for his condition.
孝明天皇は嘉永2年（1849年）頃から痔に悩まされ、他の複数の典医たちが漢方薬を用いた治療を行ったが病状は好転せず、内科的治療に限界が見えていた。