His children included Naoyuki NAGAI (eldest son), Naoyasu NAGAI (second son), Naotsune NAGAI (third son), Naosuke NAGAI (fourth son), Naoharu NAGAI (fifth son), Naonobu NAGAI (sixth son), Naomori NAGAI (eighth son), daughter (the legal wife of Tadashige TACHIBANA), daughter (the legal wife of Takanaga KORIKI), daughter (the legal wife of Tadanori MATSUDAIRA and later Yasunao MATSUDAIRA), daughter (the legal wife of Sadamasa MATSUDAIRA), daughter (the legal wife of Toshimasa MORINAGA and later the wife of Motomi OSAWA), daughter (the legal wife of Tadamori YONEKITSU), daughter (the wife of Shigetane KANBAYASHI), and daughter (the legal wife of Hirotaka KOHAMA).
子に永井尚征（長男）、永井尚保（次男）、永井尚庸（三男）、永井直右（四男）、永井尚春（五男）、永井尚申（六男）、永井尚盛（八男）、娘（立花忠茂正室）、娘（高力高長正室）、娘（松平忠憲正室のち松平康尚正室）、娘（松平定政正室）、娘（森長俊正室のち大沢基躬室）、娘（米津田盛正室）、娘（上林重胤室）、娘（小浜広隆正室）ら。