After Yoshitaka was killed in a rebellion (the revolt of Daineiji) plotted by a retainer Harukata SUE in 1551, Yoshinaga OUCHI (younger brother of Yoshishige OTOMO), who had succeeded Yoshitaka as the lord of the Ouchi clan, issued orders with his brother Yoshishige OTOMO and sent an envoy to the Ming in 1556 and 1557 for seeking the resumption of trade (from "Ming jitsuroku" [authentic account on the Ming]).
1551年（天文(元号)20）に義隆が家臣の陶晴賢による謀反（大寧寺の変）によって滅亡すると、後を継いだ大内義長（大友義鎮の弟）は、1556年（弘治(日本)2）と翌年に兄・大友義鎮とともに貿易再開を求める使者を派遣した（『明実録』）。