When Eisho Disturbance (also known as the assassination of Masamoto HOSOKAWA) happened in addition to Meio Coup, the war in and around the capital became complicated and prolonged because the battle for shogunate of the Ashikaga clan was related to the battle for Kanrei shoku (a post of shogunal deputy) of the Hosokawa clan.
明応の政変に加え、永正の錯乱まで勃発すると、足利氏の将軍職争いに細川氏の管領職争いまで絡んだため、畿内の戦乱は複雑化し、長引いた。