Troops of the Oda clan might think that war capability of Ishiyama Hongan-ji Temple somehow decreased because of blockage of supply route and, on December 17, 1578, a troop of 50,000 soldiers charged forward to Oyamazaki-cho located on the border of Yamashiro Province and Settsu Province.
補給路が途絶えた石山本願寺の戦力は幾分和らいだとみたのか、同年11月9日山城国と摂津国の国境にある大山崎町に5万兵で進軍した。