In the place of immature Ietsuna TOKUGAWA, his uncles such as the lord of the Aizu Domain Masayuki HOSHINA and Tadakiyo SAKAI took charge of the political affaires to assist the shogunate government.
幼弱の徳川家綱に代わり、幕政を補佐したのが彼の叔父に当たる会津藩主保科正之や酒井忠清等であった。