Another viewpoint claims that the Bakufu embarked on strengthening its quarantine practices in addition to establishing the Bakufu Seyaku-in (Pharmacy Institution), citing the threat of infectious diseases brought in by foreign ships entering ports in various regions in conditions that were no better than drifting ships.
漂着同然で各地に入港する外国船からの伝染病の脅威は幕府施薬院の成立と共に検疫強化に踏み切ったという見方もある。