The Saionji clan in Iyo Province, was a samurai family that dominated the whole area of Uwa County (present vicinity of Seiyo City, Ehime Prefecture) of the southwestern part of Iyo Province, from the Muromachi period to the Sengoku Period (Period of Warring States) (Japan).
伊予の西園寺氏は、室町時代から戦国時代(日本)にかけて伊予国南西部の宇和郡一帯（愛媛県西予市周辺）に勢力を持った武家である。