In 1565, when Yoshiteru was assassinated by his retainers including Hisahide MATSUNAGA, with Yoshimasa NIKI he evacuated Yoshiteru's younger brother, Kakukei (Yoshiaki ASHIKAGA), who was blockaded in Ichijo-in, sheltered Kakukei at his residence temporarily, and he followed Yoshiaki who had to move from place to place later.
永禄8年（1565年）、義輝が家臣の松永久秀らによって暗殺されると、軟禁されていた義輝の弟・覚慶（足利義昭）を仁木義政とともに一乗院より救い出して一時は自身の屋敷にも匿い、のちに放浪する義昭に付き従っている。