The damage caused by the battle was so devastating that a number of samurais who played the central role in the Azai clan such as a senior vassal Naotsune ENDO, whom, they say, Nagamasa had trusted the most, Nagamasa's own younger brother Masayuki AZAI, Iezumi YUGE and the Imamura clan were killed.
姉川の合戦における浅井家の被害は甚大で、長政が最も信頼していたと言われている重臣遠藤直経や長政の実弟浅井政之をはじめ、弓削家澄、今村氏直ら浅井家で中心的役割を果たしていた多くの武将が戦死した。