Furthermore, it was rumored that Okitsugu poisoned Ieharu due to the fact that Ieharu fell into critical condition after he took a medicine prescribed by the medical doctors (Toan HYUGA and Keijun WAKABAYASHI) whom Okitsugu recommended.
また、意次の薦めた医師（日向陶庵・若林敬順）の薬を飲んだ後に家治が危篤に陥ったため、意次が毒を盛ったのではないかという噂が流れた。