In 1246, Tokiyori expelled a group of the former shogun FUJIWARA no Yoritsune and Mitsutoki NAGOE from the bakufu because they attempted to eliminate Tokiyori (Miya-sodo (failed attempt at rebellion)) and in 1247 he eradicated the family of Yasumura MIURA who was a senior vassal (Battle of Hoji).
1246年、時頼排除を企てた前将軍・藤原頼経と名越光時一派を幕府から追放する（宮騒動）と、1247年には有力御家人である三浦泰村の一族を討滅した（宝治合戦）。