In 1387 after Yoriyasu's death, Yasuyuki TOKI, an adopted child took over the soryo position, however Yoshimitsu wanted to aggrandize power of the shogun and plotted an internal conflict in the Toki clan to weaken strong influence of the Toki clan, Yasuyuki was driven to raising an army but attacked by the army of the bakufu (Japanese feudal government headed by a shogun) and brought to ruin (The War of Yasuyuki TOKI).
嘉慶元年（1387年）に頼康が死ぬと、養子の土岐康行が惣領を継いだが、将軍権力の強化を図る義満は勢力の強すぎる土岐氏一族の内紛を画策し、康行は挙兵に追い込まれ、幕府軍の追討を受けて没落した（土岐康行の乱）。