He moved from Kyoto to Edo, together with a Chinese medicine doctor Tomohisa HASEGAWA, a Chinese medicine doctor Tomoharu KIMURA who was later adopted into Tomohisa by the marriage with his daughter and became a doctor of the Ogino Yamanaka Domain in 1853, and Eijiro TAKAHASHI who was later adopted into the Yamagishi family which had been running Kagaya (the master was known as Kagakyu), a wholesaler of glass and eyeglasses in Toriabura-cho, Nihonbashi.
漢方医長谷川友尚、漢方医木村友春（後に長谷川友尚の娘と結婚、友尚の養子となり、その後、嘉永6年（1853年）荻野山中藩医となる）、高橋栄次郎（後に日本橋通油町の硝子・眼鏡問屋加賀屋（加賀久）を営む山岸家の養子となる）とともに、京都から上京。