At the time of its publication, a book of "Kaitai Shinsho" was presented to O-oku (inner palace of Edo-jo Castle) through Hosan KATSURAGAWA who had feared of any possibility to violate taboo of bakufu (Japanese feudal government headed by a shogun).
『解体新書』刊行の際、幕府の禁に触れる可能性があったため、甫三を通じて大奥に献上されている。