After the Emperor Yomei died in 587, he was raised up as the successor to the throne, but the Soga clan, the opposition appeared, and no further activities of Oshisaka no Hikohito no Oenomiko is found in any historical documents; it is assumed that he was assassinated by the Soga clan.
用明天皇の崩御（587年）後に王位継承者として候補に挙がったらしいが、対立する蘇我系王族が台頭したため、以後の史料には活動が一切見えず、蘇我氏によって暗殺されたとの憶測もある。