In 1601, 53 shukuba from Shinagawa to Otsu were established along the Tokai-do Road, and it was here that the Tokaido Gojusan-tsugi (Fifty-Three Stations of the Tokaido) originated.
東海道では、1601年（慶長6）に品川から大津までを53駅と定め、ここに東海道五十三次が始まった。