The topics discussed in the Shoshikai covered a wide range of fields, not only merely medical science which was a mainstream of Western learning then, language, mathematics, astronomy, but also politics, economics, and national defense.
尚歯会で議論される内容は当時の蘭学の主流であった医学・語学・数学・天文学にとどまらず、政治・経済・国防など多岐にわたった。