In 645, however, the head family of the Soga clan of Soga no Emishi, the father and his son, SOGA no Iruka was destroyed in Isshi-no-hen (the Murder in the Year of Isshi).
しかし、645年（皇極天皇4年）に乙巳の変で蘇我蝦夷・蘇我入鹿親子の宗本家が滅ぼされる。