After Tadatsune died on May 26, 1709 at the age of 49, his adopted heir, Tadanao HONDA succeeded to his position (the lord of Koriyama Domain in Yamato Province).
宝永6年（1709年）4月17日、49歳で死去し、後を養嗣子の本多忠直(大和国郡山藩主)が継いだ。