In 540, when Emperor Kinmei ascended the throne, Iname was again appointed as a minister and made his two daughters, SOGA no Kitashihime and (Soga no) Oane no kimi, marry the emperor.
欽明天皇元年（540年）欽明天皇が即位すると引き続き大臣となり、娘の蘇我堅塩媛と小姉君を天皇の妃とした。