On July 22, 1690, Nagashige succeeded the territory of the late elder brother, Nagasuke and, on November 10th, was appointed as the fourth lord of the Yoshida Domain, which annually produced 45,000 koku (a unit of amount of rice: one koku of rice could feed one person for one year) in the Mikawa Province.
元禄3年(1690年)6月17日兄長祐の遺領を相続、同年10月10日に三河吉田藩4万5000石の第4代藩主となった。