During the Edo period, when Waho Igaku (ancient Japanese medicine) became an active area of study along with the promotion of the study of Japanese classical literature, the Daidoruijuho was treated as a sacred textbook for Wahoka (doctors in ancient Japanese medicine).
江戸時代、国学の振興とともに和方医学が興隆すると、同書は和方家の聖典として考えられるようになった。