After his father died at the age of 55 in 1850, he, who aspired to the thought of Sonno Joi (antiforeigner faction), changed his name to Shimenosuke SANO and left for Edo.
嘉永3年父が55歳で死去した後、尊皇攘夷を志し、名前を佐野七五三之助と改めて江戸へ出奔。