Although he retreated as soon as he heard the report on Honnoji Incident, Ujinao HOJO in Odawara City marched aiming at to take Kozuke Province and Kazumasu tried to break through the enemy lines and badly defeated and came back to his territory, Ise Nagashima-jo Castle (the Battle of Kanna-gawa River).
本能寺の変の報を聞くとすぐさま撤退するが、小田原市の北条氏直が上野国奪取を目指して進出、敵中突破を試みた一益は大敗して領国の伊勢長島城へ帰還した（神流川の戦い）。