The clan was appointed to the shugo of both Kai Province and Aki Province during the Northern and Southern Court period after the tenth head Nobutake Takeda achieved distinguished war service under Takauji ASHIKAGA.
南北朝時代に10代武田信武が足利尊氏に属して戦功を上げた結果、甲斐国と安芸国の守護に任命された。