The genealogy of the Sanponji-Uesugi family is not clear; therefore, it is not known whether they were related to Sadanaga UESUGI or Takanaga (Kagenaga) UESUGI, who served the Nagao clan in the Sengoku period.
山本寺上杉家の系譜ははっきり分かっておらず、戦国時代(日本)に長尾氏に仕えた上杉定長や上杉孝長（景長）などとの続柄は不明である。