This family produced renowned roju, such as the Izumi no kami (Governor of Izumi Province) Tadayuki, who assisted Yoshimune TOKUGAWA during the Kyoho Reforms and Tadakuni MIZUNO, who led the Tenpo Reforms.
享保の改革で徳川吉宗を補佐した和泉守忠之や天保の改革を主導した水野忠邦等、著名な老中も輩出している。