NAKATOMI no Kamatari (Fujiwara no Kamatari) was appointed to this post for the first time in history after the head family of the Soga clan fell in Isshi Coup (the Murder of the Year of Isshi) which occurred in 645.
最初である中臣鎌足（のちの藤原鎌足）は、645年乙巳の変で蘇我氏宗家が滅亡した後に任じられた。