In 1416 when Kanto Kanrei (a shogunal deputy for the Kanto region) Zenshu UESUGI rebelled against Kamakura Kubo (quasi-shogun of Kanto region) Mochiuji ASHIKAGA (War of Zenshu UESUGI) at Kamakurafu (Kamakura Government), Nobumitsu TAKEDA sided with his son-in-law Zenshu.
1416年に鎌倉府で関東管領の上杉禅秀が鎌倉公方の足利持氏に反旗を翻す（上杉禅秀の乱）と、武田信満は女婿にあたる禅秀に味方した。