The book received much criticism because doctors had strong hesitation to dissect a human body in koiho (school of ancient medicine) led by Todo YOSHIMASU, but the first human body dissection in Japan proved the accuracy of the Dutch medical literature, giving a strong impact on the medicine community.
吉益東洞ら古医方においても人体解剖には抵抗が強かったため批判を浴びるが、国内初の人体解剖は蘭書の正確性を証明し、医学界に大きな影響を与える。