Of special note is that in 1553, the Miyoshi clan expelled Shogun Yoshiteru to Kuchiki, Omi Province, and reached the zenith of its power as the virtual ruler of the areas surrounding the capital.
特に天文(日本)22年（1553年）には将軍義輝を近江国朽木に追放し、三好氏は畿内の実力者として絶頂を極めた。