Worrying about Princess Kazunomiya, Emperor Komei made her real mother Kangyoin, her menoto Fujiko TSUCHIMIKADO and the court lady Tsuguko NIWATA (a court lady of the first rank to Emperor Ninko), Katsuko ICHO go with her in order to lessen her mental uneasiness, and several doctors of Bureau of Medicine (one of the doctors also resided in Edo after her down-ranking marriage) so that she could receive the same treatment as in the capital in case she might get sick in Kanto area by any chance.
孝明天皇は和宮に配慮し、江戸城へ生母の観行院、乳母の土御門藤子、女官の庭田嗣子（仁孝天皇の典侍）、鴨脚克子を同行させて精神的な不安を軽減させたほか、典薬寮の医師も数人付随させ（うち一人は降嫁後も江戸に常駐）、万が一関東の地で病を得ても都と同じ治療が受けられるようにした。