He gained his fame by examining seii taishogun (literally, "great general who subdues the barbarians") Yoshiteru ASHIKAGA, and then such millitary commanders who were influential in Kyoto politics as Harumoto HOSOKAWA, Chokei MIYOSHI, and Hisahide MATSUNAGA, and established a medical school called Keiteki-in Medical Center in Kyoto.
征夷大将軍足利義輝を診察し、その後京都政界を左右した細川晴元・三好長慶・松永久秀などの武将にも診療を行い、名声を得て、京都に啓迪院（けいてきいん）と称する医学校を創建した。