However, their power gradually declined due to internal strife over hegemony in Kanto between the Yamanouchi-Uesugi family that was already based in Kanto and had been serving Kamakura-fu, and the Ogigayatsu-Uesugi family that originally lived in Kyoto and served Muromachi-fu.
しかし、従来より鎌倉府に仕え関東に拠点のあった山内上杉家と、当初は室町幕府に仕えて京都に在住した扇谷上杉家が、関東の覇権をかけて内紛を起こし次第に勢力を衰退させる。