He was born to Ryosen TEZUKA (his father), who worked as a Ranpoi (a person who studied Western medicine by means of the Dutch language) in Edo (current Tokyo) and as a doctor at a public clinic of Hitachifuchu Domain in Hitachi Province.
江戸の蘭方医、常陸国常陸府中藩藩医手塚良仙(父)を父に生まれる。