Muko City is located on the southwestern edge of the Kyoto Basin; to the west lies the Nishiyama Mountain Range including Mt. Oshio, and to the east outside the city flows the Katsura-gawa River (Yodo-gawa River system).
京都盆地の南西端に位置し、西方には小塩山をはじめとする西山連峰を望み、市外東方には桂川(淀川水系)が流れる。