This was the highest official rank among members from the Soga (or Ishikawa) clan after his grandfather Yasumaro, and he finally ended his life at the age of 74 in 762, when a dark sign began to be seen in the influence of Nakamaro due to Empress Komyo's death, which occurred shortly after Toshitari's taking office, and the rise of Dokyo, a priest who healed the Retired Empress Koken.
これは祖父・安麻呂以降の蘇我氏（石川氏）出身者としては最も高い官位であったが、直後の光明皇后の崩御、孝謙上皇の病を直した道鏡の台頭等仲麻呂の権勢に陰りが見え始めてきた762年に74歳の生涯を閉じた。