Early in the morning of July 1, 1582, when Mitsuhide AKECHI raided Nobunaga ODA on Honno-ji Temple (in the so-called Honno-ji Incident), Sadaoki ISE led a 2000-strong force in attacking Nobunaga ODA's eldest son, Nobutada ODA, at Nijo-jo Castle and he himself fought hard, wielding his spear.
天正10年6月2日(旧暦)（1582年6月21日）の明朝、明智光秀は織田信長を本能寺に攻めた（所謂、本能寺の変）の際、伊勢貞興は麾下の二千の兵を率いて織田信長の長男、織田信忠を二条城に攻め、自ら槍を振るって奮戦した。