Katsumoto HOSOKAWA became the commander-in-chief for the eastern army in the Onin War, and his son Masamoto HOSOKAWA took over the real power of the bakufu, ousting the 10th Shogun Yoshitane ASHIKAGA in the Meio Coup.
応仁の乱で細川勝元は東軍の総帥となり、その子細川政元は明応の政変で10代将軍足利義稙を退けて幕府の実権を掌握した。