However, supported by the trend toward expulsion of foreigners and national isolation arising in reaction to the opening of Japan to the world, the bakufu promoted full-fledged enforcement of the law from 1863, and as a result it began to produce material results slowly such as the decreased exports of raw silk thread.
だが、開国の反動から攘夷鎖国への傾向が出てきたことを背景に、1863年（文久3年）から、幕府は同法令の本格施行を強め、その結果、生糸輸出が減少するなど次第に実効が現れていった。