Especially, Masamoto HOSOKAWA expelled Yoshitane ASHIKAGA, seii taishogun (literally, "great general who subdues the barbarians"), backed up Yoshizumi ASHIKAGA who was still too young to become the next shogun, made Yoshizumi a puppet, and controlled the politics of the bakufu, and the Muromachi bakufu, in fact, became the administration of the Hosokawa clan.
特に管領細川政元は征夷大将軍足利義稙を追放し、次期将軍に幼い足利義澄を擁立しこれを傀儡化させ、幕政を牛耳っており、室町幕府は事実上、細川氏の政権となった。