Watch out for Gale Sondergaard!
By 1945, Universal’s monster pictures had run their course and the studio was seeking new sources for thrillers. Drawing on a villain from one of its Sherlock Holmes films, the studio put a female version of a mad doctor at the center of “The Spider Woman Strikes Back.”<br /><br />Gale Sondergaard (“The Cat and the Canary”) returned in the role she originated as Adrea Spedding in the whodunit “The Spider Woman.” In “The Spider Woman Strikes Back,” she is given a completely different identity as Zenobia Dollard, a wealthy woman pretending to be blind in order to attract young women in search of employment as companions. With the help of her horribly deformed assistant Mario (Rondo Hatton), she drains their blood and uses it in her experiments with plants and insects. Her newest employee is Jean Kingsley (Brenda Joyce).<br /><br />Jean has been told that Dollard can’t seem to retain companions for long but disregards this danger sign. She is wary, however, of mute Mario, eerily lurking about. Dollard is very kind to her, even persuading her to drink a glass of milk every night for her health. Unbeknownst to Jean, the milk is drugged so that she will remain asleep while Dollard and Mario sneak into her bedroom and harvest her blood.<br /><br />This low-budget movie benefits considerably from Sondergaard’s performance. Her Zenobia Dollard is the perfect monster. In appearance she is kind, helpless, and vulnerable. In actuality she is obsessed with creating a death serum by feeding human blood to exotic plants and spiders. More self-controlled than her male movie counterparts, she exudes an aura of menace amplified by her low-keyed performance. This is not a woman you’d want to invite you to tea.<br /><br />Joyce is the requisite damsel in distress and does an adequate job of finding certain things around the large mansion odd, eliciting sympathy, and learning things about her employer along with the viewer. The role is one that any actress could play and Joyce adds nothing special in her performance.<br /><br />Rondo Hatton’s Mario is perhaps the most interesting character, even though he never speaks. Hatton was afflicted with a disease called acromegaly that caused his head to enlarge and his face to become deformed. Lit atmospherically, he takes on the appearance of a monster. Since the rest of the film is fairly light on horror, his presence is particularly important.<br /><br />Arthur Lubin, who had great success at Universal directing its Abbott & Costello films and the Technicolor remake of “The Phantom of the Opera,” relies mostly on creative use of shadows, Sondergaard’s sinister placidity, and Hatton’s creeping about to create a sense of foreboding. He uses sets and the studio backlot to keep costs down and exerts little imagination in staging scenes. He creates suspense only intermittently, even when the script offers opportunities to build and sustain it. Too often, dialogue is excessive yet characters are underdeveloped. The running time of just under an hour could have been expanded somewhat to flesh out their relationships. Sondergaard and Hatton are the main attractions.<br /><br />Bonus materials on the unrated Blu-ray release from Kino-Lorber include an audio commentary, a making-of featurette, and several theatrical trailers.<br /><br />Made and marketed as a B picture, “The Spider Woman Strikes Back” is a melodrama that holds the viewer’s attention. Zenobia Dollard and Mario are a menacing duo but never achieve the intensity or stature of Universal’s Frankenstein, Dracula, and Mummy movies. It remains a curious but failed attempt to establish yet another “monster” franchise.
The movie title "The Spider Woman Strikes Back," available on Movies & TV, has received an average rating of 3.9 from 65 reviewers. 
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 {"Genre": "Horror", "Format": "NTSC", "Contributor": "Kirby Grant, Rondo Hatton, Brenda Joyce, Arthur Lubin, Gale Sondergaard, Milburn Stone, Hobart CavanaughKirby Grant, Rondo Hatton, Brenda Joyce, Arthur Lubin, Gale Sondergaard, Milburn Stone, Hobart Cavanaugh  See more", "Language": "English, English", "Runtime": "59 minutes", "MPAA rating": "NR (Not Rated)", "Product Dimensions": "6.77 x 5.28 x 0.55 inches; 2.2 Ounces", "Director": "Arthur Lubin", "Media Format": "NTSC", "Run time": "59 minutes", "Release date": "November 2, 2021", "Actors": "Gale Sondergaard, Rondo Hatton, Brenda Joyce, Kirby Grant, Milburn Stone", "Subtitles": "English", "Studio": "Kl Studio Classics", "Country of Origin": "USA", "Number of discs": "1"}

Here is a brief synopsis of the title : Gale Sondergaard (The Cat and the Canary, The Mark of Zorro) returns as the sinister Spider Woman, a role she originated as the femme fatale Adrea Spedding in the Sherlock Holmes whodunit The Spider Woman. In this non-canonical spin-off, she is even more diabolical as Zenobia Dollard, a wealthy blind woman shrouded in mystery. Jean (Brenda Joyce, Jane in several Tarzan films) is hired as Zenobia’s caretaker after all the preceding caretakers vanish without a trace. She becomes entangled in a web of horror as she discovers that her employer, aided by a hideously deformed household servant played by legendary creeper Rondo Hatton (The Pearl of Death, The Brute Man), has used the blood of her predecessors to create a death serum when it is mixed with spider venom—and that her own blood is now being harvested at night, while she is in a drugged sleep, to continue the experiment. Veteran director Arthur Lubin (Hold That Ghost, Ali Baba and the Forty Thieves) delivers a terrifying tale chock-full of bizarre blood-drinking plants, old-dark-house spookiness and the wickedness of the Spider Woman!.