however , according to the may issue of rheumatic disease clinics of north america , this is of scientific interest but `` probably not very important clinically because non-steroidal inflammatory drugs -lrb- such as naprosyn , nuprin or advil -rrb- are more potent -lrb- than fish oil -rrb- and are well tolerated by the population at large. '' ; rheumatoid arthritis is a chronic disease characterized by symmetrical inflammation of the joints -- usually wrists and fingers , and often knees , shoulders , hips and the spine. ;