When military conflicts broke out between the Ottoman Empire and other states, Greeks usually took up arms against the Ottomans, with few exceptions. Prior to the Greek Revolution of 1821, there had been a number of wars which saw Greeks fight against the Ottomans, such as the Greek participation in the Battle of Lepanto in 1571, the Epirus peasants' revolts of 1600–1601 (led by the Orthodox bishop Dionysios Skylosophos), the Morean War of 1684–1699, and the Russian-instigated Orlov Revolt in 1770, which aimed at breaking up the Ottoman Empire in favour of Russian interests. These uprisings were put down by the Ottomans with great bloodshed. On the other side, many Greeks were conscripted as Ottoman citizens to serve in the Ottoman army (and especially the Ottoman navy), while also the Ecumenical Patriarchate of Constantinople, responsible for the Orthodox, remained in general loyal to the empire.