Charles IV died in 1378. During the reign of his son, King Wenceslaus IV (1378–1419), a period of intense turmoil ensued. During Easter 1389, members of the Prague clergy announced that Jews had desecrated the host (Eucharistic wafer) and the clergy encouraged mobs to pillage, ransack and burn the Jewish quarter. Nearly the entire Jewish population of Prague (3,000 people) was murdered.