Ecuador was placed in 96th position of innovation in technology in a 2013 World Economic Forum study. Ecuador was ranked 99th in the Global Innovation Index in 2019 and 2020. The most notable icons in Ecuadorian sciences are the mathematician and cartographer Pedro Vicente Maldonado, born in Riobamba in 1707, and the printer, independence precursor, and medical pioneer Eugenio Espejo, born in 1747 in Quito. Among other notable Ecuadorian scientists and engineers are Lieutenant Jose Rodriguez Labandera, a pioneer who built the first submarine in Latin America in 1837; Reinaldo Espinosa Aguilar (1898–1950), a botanist and biologist of Andean flora; and José Aurelio Dueñas (1880–1961), a chemist and inventor of a method of textile serigraphy.