In 2010, coronary artery disease, lung cancer, stroke, chronic obstructive pulmonary diseases, and traffic accidents caused the most years of life lost in the U.S. Low back pain, depression, musculoskeletal disorders, neck pain, and anxiety caused the most years lost to disability. The most harmful risk factors were poor diet, tobacco smoking, obesity, high blood pressure, high blood sugar, physical inactivity, and alcohol use. Alzheimer's disease, substance use disorders, kidney disease, cancer, and falls caused the most additional years of life lost over their age-adjusted 1990 per-capita rates. U.S. teenage pregnancy and abortion rates are substantially higher than in other Western nations, especially among blacks and Hispanics.