In the 1500s, the Portuguese became acquainted with the Vietnamese coast, where they reportedly erected a stele on the Chàm Islands to mark their presence. By 1533, they began landing in the Vietnamese delta but were forced to leave because of local turmoil and fighting. They also had less interest in the territory than they did in China and Japan. After having successfully settled Macau and Nagasaki to begin the profitable Macau–Japan trade route, the Portuguese began to involve themselves in trade with Hội An. Portuguese traders and Jesuit missionaries under the ''Padroado'' system were active in both Vietnamese realms of ''Đàng Trong'' (Cochinchina or Quinan) and ''Đàng Ngoài'' (Tonkin) in the 17th century. The Dutch also tried to establish contact with Quinan in 1601 but failed to sustain a presence there after several violent encounters with the locals. The Dutch East India Company (VOC) only managed to establish official relations with Tonkin in the spring of 1637 after leaving Dejima in Japan to establish trade for silk. Meanwhile, in 1613, the first English attempt to establish contact with Hội An failed following a violent incident involving the Honourable East India Company. By 1672 the English managed to establish relations with Tonkin and were allowed to reside in Phố Hiến.