In 1400, the Muslim Turco-Mongol conqueror Tamurlane invaded Syria, in which he sacked Aleppo, and captured Damascus after defeating the Mamluk army. The city's inhabitants were massacred, except for the artisans, who were deported to Samarkand. Tamurlane also conducted specific massacres of the Aramean and Assyrian Christian populations, greatly reducing their numbers. By the end of the 15th century, the discovery of a sea route from Europe to the Far East ended the need for an overland trade route through Syria.