During the 50-day Ottoman siege of the city in 1570, the cathedral provided refuge for a great number of people. When the city fell on 9 September, Francesco Contarini, the Bishop of Paphos, delivered the last Christian sermon in the building, in which he asked for divine help and exhorted the people. The cathedral was stormed by Ottoman soldiers, who broke the door and killed the bishop along with others. They smashed or threw out Christian items, such as furniture and ornaments in the cathedral and destroyed the choir as well as the nave. Then, they washed the interior of the mosque to make it ready for the first Friday prayer that it would host on 15 September, which was attended by the commander Lala Mustafa Pasha and saw the official conversion of the cathedral into a mosque. During the same year, the two minarets were added, as well as Islamic features such as the mihrab and the minbar.