Italy has been the final destination of the Silk Road for many centuries. In particular, the construction of the Suez Canal intensified sea trade with East Africa and Asia from the 19th century. Since the end of the Cold War and increasing European integration, the trade relations, which were often interrupted in the 20th century, have intensified again and the northern Italian ports such as the deep-water port of Trieste in the northernmost part of the Mediterranean with its extensive rail connections to Central and Eastern Europe are once again the destination of government subsidies and significant foreign investment.