Long-distance rail lines connect Berlin with all of the major cities of Germany and with many cities in neighboring European countries. Regional rail lines of the  provide access to the surrounding regions of Brandenburg and to the Baltic Sea. The  is the largest grade-separated railway station in Europe.  runs high speed Intercity-Express trains to domestic destinations like , Munich, Cologne, ,  and others. It also runs an airport express rail service, as well as trains to several international destinations like Vienna, Prague, , Warsaw, Wrocław, Budapest and Amsterdam.