Since medieval times the episcopal see of Rome has been recognized as a sovereign entity. The Holy See (not the State of Vatican City) maintains formal diplomatic relations with and for the most recent establishment of diplomatic relations with  sovereign states, and also with the European Union, and the Sovereign Military Order of Malta, as well as having relations of a special character with the Palestine Liberation Organization; 69 of the diplomatic missions accredited to the Holy See are situated in Rome. The Holy See maintains 180 permanent diplomatic missions abroad, of which 74 are non-residential, so that many of its 106 concrete missions are accredited to two or more countries or international organizations. The diplomatic activities of the Holy See are directed by the Secretariat of State (headed by the Cardinal Secretary of State), through the Section for Relations with States. There are 13 internationally recognized states with which the Holy See does not have relations. The Holy See is the only European subject of international law that has diplomatic relations with the government of the Republic of China (Taiwan) as representing China, rather than the government of the People's Republic of China (see Holy See–Taiwan relations).