One of the most notable hospitals is the Hôtel-Dieu, founded in 651, the oldest hospital in the city, although the current building is the product of a reconstruction of 1877. Other hospitals include Pitié-Salpêtrière Hospital (one of the largest in Europe), Hôpital Cochin, Bichat–Claude Bernard Hospital, Hôpital Européen Georges-Pompidou, Bicêtre Hospital, Beaujon Hospital, the Curie Institute, Lariboisière Hospital, Necker–Enfants Malades Hospital, Hôpital Saint-Louis, Hôpital de la Charité and the American Hospital of Paris.