Colombia has been inhabited by various indigenous peoples since at least 12,000 BCE, including the Muisca, Quimbaya, and the Tairona. The Spanish landed first in La Guajira in 1499 and by the mid-16th century colonized parts of the region, establishing the New Kingdom of Granada, with Santafé de Bogotá as its capital. Independence from the Spanish Empire was achieved in 1819, with what is now Colombia emerging as the United Provinces of New Granada. The new nation experimented with federalism as the Granadine Confederation (1858), and then the United States of Colombia (1863), before the Republic of Colombia was finally declared in 1886. Panama seceded in 1903, leading to Colombia's present borders. Beginning in the 1960s, the country has suffered from an asymmetric low-intensity armed conflict and political violence, both of which escalated in the 1990s. Since 2005, there has been significant improvement in security, stability, and rule of law, as well as unprecedented economic growth and development.