Guorui Deng - Doctoral Candidate
Guorui Deng, BS
PhD Student (Department of Cancer Biology)
Education: BS – Biochemistry/Cell Biology, Bucknell University, Lewisburg, PA
Laboratory Department: Department of Cancer Biology, Hypertension and Vascular Research Center
Advisors: Dr. Ann Tallant and Dr. Patricia E. Gallagher
Current Research: My research focuses on determining the molecular mechanisms for the inhibition of triple negative breast cancer growth and progression by the heptapeptide hormone Angiotensin-(1-7), [Ang-(1-7)]. I am interested in identifying mechanisms of how the heptapeptide hormone exerts its anti-cancer effects on the oncogenic c-Met receptor tyrosine kinase and its downstream signaling to inhibit disease progression and subsequent metastasis. Successful completion of my studies will provide support for Ang-(1-7) to serve as a novel targeted therapeutic for these patients.
Guorui Deng, Patricia E. Gallagher, E. Ann Tallant. “Angiotensin-(1-7) Attenuates Triple Negative Breast Cancer Progression By Targeting C-Met Signaling and Downstream ERK1/2 Signaling,” (2014), RAS Oncogenes: From Biology to Therapy, Lake Buena Vista, FL, Poster Presentation.
Guorui Deng, Patricia E. Gallagher, E. Ann Tallant. “Angiotensin-(1-7) Attenuates Triple Negative Breast Cancer Progression By Targeting C-Met Signaling,” (2013), Wake Forest University Department of Surgical Sciences Research Day, Poster Presentation.
Honors and Awards:
Recipient of Department of Cancer Biology Training Grant, 08/2013
Bucknell University Full Tuition Scholarship Award, 2006-2010