There is still to learn from the DES tragedy
2011 Study Abstract
Synthetic oestrogens such as diethylstilbestrol (DES) or 17-alpha-ethinylestradiol (EE) administered to pregnant women during numerous years were demonstrated as responsible of severe ravages for children.
Perturbateurs endocriniens et troubles du comportement : non, nous n’avons pas encore tiré toutes les leçons de l’histoire du DES, ResearchGate publication/251710210, Médecine et Longévité 3(2):67-74, June 2011.
Image credit Pascal Böhme.
Regarding behavior disorders, works on mice or rat have shown the effects of these xeno-hormones used even at very weak dose, time of fetal exposition being crucial.
Works are less numerous for humans but recent analysis of the spontaneous Hhorages cohort brings demonstrative data. Analogy between animal and man is discussed as well as the effects of bisphenol A and organophosphate pesticides.